Physician Interview: William Salt, M.D., and Edwin Season, M.D., on
Transcription
Physician Interview: William Salt, M.D., and Edwin Season, M.D., on
PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 YOUR PURCHASE FUNDS RESEARCH In this issue... • Physician Interview: William Salt, M.D., and Edwin Season, M.D., on Treating Fibromyalgia 1 • Physician Interview: Richard Shames, M.D., on Treating Thyroid Dysfunction, Chronic Fatigue Syndrome and Fibromyalgia 1 • Research and Drug News Briefs 2 • Interview with Dale Guyer, M.D., on Insulin Potentiation Therapy for Chronic Fatigue Syndrome & Fibromyalgia Patients 4 • Healing Chronic Illness at Home: Oxygen, Ozone, Sauna and Detoxification for Lyme Disease, Fibromyalgia, Chronic Fatigue Syndrome and MCS 9 Physician Interview: William Salt, M.D., and Edwin Season, M.D., on Treating Fibromyalgia Physician Interview: Richard Shames, M.D., on Treating Thyroid Dysfunction, Chronic Fatigue Syndrome and Fibromyalgia William B. Salt II, M.D., is board-certified in both internal medicine and gastroenterology. He received his M.D. degree from The Ohio State University in Columbus, Ohio, in 1972, where he currently holds an appointment as Clinical Associate Professor in Medicine. He trained for five more years in internal medicine and gastroenterology at Vanderbilt University Hospitals in Nashville, Tennessee, where he also served as a Chief Resident in Medicine. Edwin H. Season, M.D. Richard Shames, M.D., graduated Harvard and University of Pennsylvania, did research at the National Institutes of Health with Nobel Prize winner Marshall Nirenberg, and has been in private practice for twenty-five years. In addition to his medical office work, he has been a member of the Clinical Faculty of the University of California Medical Center in San Francisco, a founding member of the American Holistic Medical Association, a participant in the Carl Menninger Foundation, and a member of Who’s Who in California as well as nationally. Dr. Shames has published a number of health-related books and is well-known for his prominence and pioneering work in the holistic field. His newest book is “Thyroid Power.” William B. Salt II, M.D. Edwin H. Season, M.D., is board-certified in orthopedic surgery. He received his M.D. degree from The Ohio State University in Columbus, Ohio, in 1971, followed by internship at the University of Virginia. He then returned to Ohio State for his residency and upon its completion, taught orthopedic surgery as an assistant professor in The Ohio State University College of Medicine from 1976 to 1980. Karilee Shames R.N., Ph.D., is a Clinical Specialist in Psychiatric Nursing and a Certified Holistic Nurse.She has maintained a private practice in collaboration with Dr. Richard Shames for twenty years, specializing in comprehensive treatment aspects of energy-depletion illnesses. Before we begin, I (Dr. Salt) must issue a disclaimer. I am a gastroenterologist, which is a subspecialty of internal medicine in digestive and liver disease. I became interested in fibromyalgia, because up to two thirds of patients with functional gastrointestinal disorders - and irritable bowel syndrome in particular - also suffer with fibromyalgia. Science is confirming that these conditions share a common link, which is a disturbance or “dysregulation” in the central nervous system and in the connections between brain and body. ImmuneSupport.com: Dr. Shames, please provide a little background on how you came to specialize in the treatment of thyroid problems. Dr. Shames: I first was amazed at how important thyroid was during undergraduate training at Harvard. I was in a biochemistry class when the professor told us that all the energy reactions in the body depend on the presence of thyroid hormone. This surprised me, but was later confirmed in medical school when the professors in anatomy class called the thyroid “The True Master Gland”, not the pituitary. The reason that the digestive tract (or gut) is so commonly involved in this dysregulation is that there are two brains in the body and they are connected. One is the brain within the skull and is part of the central nervous system, or CNS. There is a second brain in the lining of the gastrointestinal tract called the enteric nervous system, or ENS. The professor explained that the pituitary is simply a relay station for brain signals. The thyroid however, secretes the hormone that allows DNA to be read, AND Dr. Jack Wood, a renowned physiologist at The Ohio Continued on page 4 ImmuneSupport.com Continued on page 8 1 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Research and Drug News Briefs dietary supplement, NT Factor™ (NTF). In addition, they determined whether mitochondrial function, as defined by transport of the redox dye Rhodamine-123, could be reduced in aging subjects with mild to moderately severe fatigue, and whether that could be reversed with NTF supplementation in concert with improvement in fatigue scores. Participants with mild to moderately severe fatigue, who fulfilled the entry requirements were admitted to the study when their fatigue could not be explained by an obvious clinical condition. Twenty of the respondents (mean age = 68.9 +/- 4.18) completed the first part of the study on NTF for 12 weeks, and 16 of these subjects who agreed to discontinue the product also completed a wash-out period for an additional 12 weeks. Fatigue and mitochondrial function were determined every four weeks during the study. There was a time-dependent reduction in overall fatigue in moderately fatigued subjects (P < .001) but not in mildly fatigued subjects. Milnacipran Clinical Study Demonstrates Effective Treatment of Fibromyalgia Pain is Distinct from Treatment of Mood In December 2003, Cypress Bioscience announced data from its Phase II Fibromyalgia Syndrome (FMS) study demonstrating that treatment with milnacipran was equally effective in reducing pain for both depressed and non-depressed patients. However, the response rate in patients treated with placebo was considerably lower in non-depressed patients than in those patients who met criteria for major depression at the time of entry into the trial. These data indicate that the therapeutic benefits of milnacipran observed in the study are a result of its analgesic (pain elimination) properties, rather than secondary to its ability to improve mood. Milnacipran is currently being evaluated in a Phase III program for the treatment of FMS, a complex widespread pain syndrome that affects an estimated 5 million to 11 million Americans. Mitochondrial function at four and eight weeks of NTF use in moderately fatigued subjects increased by 15% and 26.8%, respectively, and restored mitochondrial function to levels similar to those found in healthy young adults. No further increase was noted between 8 and 12 weeks. Post-NTF there was a slow redevelopment of fatigue and a fall in mitochondrial function in moderately fatigued subjects, indicating that continued use of NTF may be necessary to maintain lower fatigue scores and maintain mitochondrial function. The dietary supplement with NTF reduced moderate fatigue and increased mitochondrial function in aged subjects but had no effect upon mild fatigue expression. (Source: Journal of Chronic Fatigue Syndrome, Vol. 11(3) 2003, pp. 23-36. Read the complete abstract at http://www.ImmuneSupport.com/library/ showarticle.cfm/id/5179). Milnacipran is a novel dual-acting agent that acts on two key neurotransmitters in the human body, norepinephrine and serotonin, which are involved with the central modulation and processing of chronic pain. Previously announced data from the Phase II study provides evidence that milnacipran may be an effective treatment for the pain and other symptoms associated with FMS such as fatigue, sleep disturbances, and depression. “The patients in the Phase II study who were treated with milnacipran exhibited superior pain relief compared to the placebo-treated patients,” noted Jay D. Kranzler, M.D., Ph.D., chairman of the board and chief executive officer of Cypress. “The fact that milnacipran worked equally well for both non-depressed and depressed patients, whereas the non-depressed patients had a lower placebo response rate than the depressed group, is important to our understanding of FMS. It suggests that the pain experienced by these patients is not directly related to their mood. The effective treatment of FMSrelated pain is therefore distinct from the treatment of the patients’ depression.” (Read the complete study at http://www.ImmuneSupport.com/library/ showarticle.cfm/id/5251/). Topical Geranium Oil Proves Helpful for Easing Chronic Neuropathic Pain In 1992, geranium oil (the active ingredient in Neuragen™ PN) was tested in a multicenter, monitored, placebocontrolled study for safety and efficacy in the treatment of post-herpetic neuralgia (PHN). This is a chronic neuropathic pain condition caused by an outbreak of shingles (Herpes zoster). The study design applied one treatment per day in a single-blinded, randomized, prospective, balanced crossover study of five groups of six patients each (30 patients total). Five treatments were tested: 100% geranium oil, 50% geranium oil with mineral oil, 10% geranium oil, 0% geranium oil (placebo), and Zostrix (capsaicin 0.025%) as a positive control. Spontaneous and evoked (allodynia) pain were measured on two scales (5 point category scale and visual analog scale) several times during the hour following application. The trial was conducted at two centers: National Pain Institute, CA and Pennington Research Phospholipid Supplement Restores Mitochondrial Function and Reduces Moderately Severe Fatigue in Clinical Study Decreased mitochondrial function is a characteristic of aging and fatigue. Researchers recently determined whether mild to moderately severe fatigue in a group of aged subjects (mean age > 60 years), as defined by the validated Piper Fatigue Scale (PFS), could be significantly improved by use of a glycophospholipid (phospholipid) ImmuneSupport.com 2 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Institute, LA. vaccine directed toward these viruses could be indicated.” Also, an antiviral agent called pleconaril, “acting during the early phases of the viral cycle, could also be useful in muscular diseases clearly associated with enterovirus.” This is being tried in some cases of heart-muscle enlargement, Pozzetto said, but “it is too early to answer for muscular diseases.” (Source: Journal of Medical Virology, December 2003. Read the article at http://www.ImmuneSupport.com/library/ showarticle.cfm/id/5285/). The results are statistically significant, and showed that better than 3 out of 5 patients reported effective pain relief. Geranium oil began relieving pain within 5 to 15 minutes and relief was still increasing at the end of one hour. Pain returned to baseline by 24 hours. Side effects from geranium oil were minor and no different than mineral oil. Geranium oil was determined to be a safe and rapidly effective topical treatment for the pain of post-herpetic neuralgia. (Source: Origin BioMedicinals, Inc., 2003. Read the article at http:// www.ImmuneSupport.com/library/showarticle.cfm/id/ 5041/). Free Radicals and Antioxidants in Primary Fibromyalgia: An Oxidative Stress Disorder? The role of free radicals in fibromyalgia is controversial. In this study, 85 female patients with primary fibromyalgia and 80 age-, height-, and weight-matched healthy women were evaluated for oxidant/antioxidant balance. Malondialdehyde is a toxic metabolite of lipid peroxidation used as a marker of free radical damage. Superoxide dismutase is an intracellular antioxidant enzyme and shows antioxidant capacity. Pain was assessed by visual analog scale. Tender points were assessed by palpation. Age, smoking, body mass index (BMI), and duration of disease were also recorded. Malondialdehyde levels were significantly higher and superoxide dismutase levels significantly lower in fibromyalgic patients than controls. Age, BMI, smoking, and duration of disease did not affect these parameters. We found no correlation between pain and number of tender points. In conclusion, oxidant/antioxidant balances were changed in fibromyalgia. Increased free radical levels may be responsible for the development of fibromyalgia. These findings may support the hypothesis of fibromyalgia as an oxidative disorder. (Source: Rheumatol Int. 2003 Dec 20. Read the abstract at http: //www.ImmuneSupport.com/library/showarticle.cfm/ID/ 5269). HW Virus Seen in Muscles from Chronic Fatigue Syndrome Patients A persistent enterovirus infection in muscles may be to blame for some cases of chronic fatigue syndrome and others with chronic inflammatory muscle disease (including fibromyalgia), a French team reports. They detected genetic material (specifically RNA) from enteroviruses in 20 percent of muscle biopsies from patients with chronic inflammatory muscle diseases and 13 percent of patients with fibromyalgia/chronic fatigue syndrome, but not from healthy volunteers. The findings favor a persistent infection involving defective viral replication as a cause of these conditions. “The persistence of defective or infectious enteroviruses is well established for a lot of organs,” Dr. Bruno Pozzetto from the University Hospital Center of Saint-Etienne, France, told Reuters Health. Such infections have been documented in the heart, with possible involvement in heart enlargement; in pancreatic cells, possibly linked to juvenile diabetes; and in the central nervous system in association with a syndrome that afflicts aging survivors of polio, the researcher explained. “However, the link between these diseases, as well as chronic inflammatory muscle diseases, and viral persistence is not clear,” he said. Pozzetto and colleagues investigated the presence of enterovirus in skeletal muscle biopsies from 15 patients with chronic inflammatory muscle diseases, 30 patients with fibromyalgia/chronic fatigue syndrome, and 29 healthy subjects to test their hypothesis that skeletal muscle may play host to persistent enteroviral infection. Three patients with chronic inflammatory muscle disease and four patients with fibromyalgia/chronic fatigue syndrome were positive for enterovirus RNA, the team reports in the Journal of Medical Virology. None of the muscle biopsies in this study contained a particular viral protein, the researchers note, which “suggests a defective viral replication.” It is too early to derive implications for treatment from these results, Pozzetto said. However, he noted that so-called Coxsackie B viruses seem to play a key role in persistent muscular infections. “To prevent this persistence, an inactivated ImmuneSupport.com For the most current RESEARCH AND TREATMENT NEWS visit www.ImmuneSupport.com today and sign up for the WEEKLY EMAIL BULLETIN 3 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Salt, M.D., Season, M.D., continued from page 1 Interview with Dale Guyer, M.D., on Insulin Potentiation Therapy for Chronic Fatigue Syndrome & Fibromyalgia Patients State University calls the ENS “the little-brain-in-thegut.” The CNS and ENS closely resemble one another, because they both develop from the same embryonic tissue. Later, they take different developmental paths, but they continue to have similar nerve tissue and neurochemical communication receptor sites. All of the neurochemicals in the CNS are also found in the ENS (e.g., serotonin). The two brains function independently and interdependently and mutually influence one another. The brain affects the gut and the gut affects the brain. Dale Guyer, M.D., is a holistic family physician and Director of the Advanced Medical Center in Zionsville, Indiana, where patients are offered a unique blend of traditional and alternative therapies incorporating a mind-body-spirit approach for a variety of health issues, including Chronic Fatigue Syndrome and fibromyalgia. This is the mind/brain-gut connection, and when there is malfunction of the connection, functional symptoms that result in functional diagnoses, such as irritable bowel syndrome can occur. HEALTHwatch (HW): In a previous article we discussed a promising novel therapy called Insulin Potentiation Therapy (IPT) for the adjunctive treatment of Chronic Fatigue Syndrome (CFS) and Fibromyalgia Syndrome (FMS). Dr. Guyer, could you please explain again to our readers what IPT is and the rationale for its use in treating CFS/FMS? I believe that people are overwhelmed and confused by information - and much of it is misinformation - about their problems and that it is difficult for them to find comprehensive, contemporary and scientifically-based information that can be translated into knowledge (since information and knowledge are not the same). Dr. Guyer: In its simplest description, IPT uses a low dose of insulin to amplify or potentiate the activity of a drug or nutrient with which it is administered. This can be a significant advantage when using any pharmaceutical with potential side effects such as chemotherapy medicines. In this instance a low dose (about 1/10 the usual dose) of the drug can be given since its activity is modified by insulin (information is available about this treatment at www.IPTQ.com.) Although IPT has been used to treat many medical conditions, to my knowledge we are the first to be using this method to treat CFS/FMS. Furthermore, even if doctors shared a common understanding of functional symptoms and disorders (and they do not), most generally do not have sufficient time to provide adequate patient education and assist patients to help themselves. With this in mind, I have invited a well-respected musculoskeletal specialist to coauthor the answers here. Ed Season, M.D., is an orthopedic surgeon with a special interest in helping people without surgery. He is my coauthor in the book, “Fibromyalgia and the MindBodySpirit Connection.” The interesting thing is that this adjunctive inclusion (IPT) has had success in recalcitrant cases where other approaches have yielded negligible results, which has been an encouraging finding. As we are all aware, there remain many who suffer with CFS/FMS who have really tried everything, in terms of comprehensive therapies, but have had marginal success. I have found for many that we have treated, IPT has really been the ‘icing on the cake’ that has propelled them over the unwellness hump. ImmuneSupport.com: You have described fibromyalgia (FM) as a functional illness. Please explain what that means for patients seeking appropriate treatment. Bill Salt, M.D.: The medical term, “functional” refers to a disturbance in how the body works. Medical tests, such as X-rays, endoscopy, and blood tests either fail to explain the symptoms or show findings that are not the cause of the problem. All too commonly, a functional diagnosis leads to patient - physician misunderstanding, with the patient either thinking or saying, “Do you mean that the problem is all in my head?” We will examine this premise later in the interview. HW: This sounds promising. At this time how many patients have been treated with IPT and what approximate percentage has clinically improved? ImmuneSupport.com: Many of our readers are confused by the sometime classification of fibromyalgia as an autoimmune disease. Do you think FM is an autoimmune disorder? Dr. Guyer: To date we have treated about 45 patients using IPT as an adjunctive therapy. Most will, over time, receive anywhere from 3-12 treatments depending on individual need. Of these patients I have felt like there were about 2-3 people in whom I had not seen any favorable response. (They had only 2 treatments, however.) Otherwise, I would estimate about 80% Bill Salt, M.D.: No. On the website of the University of Michigan Chronic Pain & Fatigue Research Center (http: Continued on page 5 ImmuneSupport.com 4 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Salt, M.D., Season, M.D., continued from page 4 of patients treated with IPT experience a significant functional improvement. Dr. Guyer: Yes, that is an individual variable. Most will notice a significant boost with 2 or 3 treatments, but others will take 6 or 7 before noticing a clinical change. //www.med.umich.edu/painresearch/index.htm), Dr. Dan Clauw and colleagues discuss the differential diagnosis of fibromyalgia. Fibromyalgia may present similarly to a number of disorders or concurrently (at the same time) with other disorders - such as autoimmune disorders - that may confuse the diagnosis. Unlike fibromyalgia, autoimmune diseases include inflammation of the synovial membranes that line the spaces between bones and joints and secrete a thick, lubricating fluid. HW: These results seem very promising, especially given the fact that this initial group of patients were non-responders to other forms of therapy tried (both conventional and alternative.) Are you now starting to use this treatment as an initial therapy with your other CFS/FMS patients? ImmuneSupport.com: In addition to the primary symptom, pain, fatigue, refreshing sleep and IBS are common problems for FM patients. How do you go about treating these symptoms - do you utilize both traditional and alternative therapies? If so, what has worked best for most patients in your experience? Dr. Guyer: Yes. To date I am finding this approach even more promising with “typical” CFS/FMS patients. Bill Salt, M.D.: We take the position that the most important aspects of treatment include helping patients understand that, 1) their symptoms are real and not imagined, 2) science is revealing the reality of alterations and disturbances in the brain/body connection to account for them, 3) there can be a cognitive belief and spiritual dimension to health, coping and healing, 4) self-care - including exercise and healthy diet - are very important, and 5) there are medications that may be helpful in the management of predominant symptoms. HW: It seems that for some patients, there is a direct correlation between the total number of treatments they receive and the degree of improvement. HW: What are the patient criteria you have observed that tend to be associated with an increased likelihood of improvements? Dr. Guyer: Generally the pattern I have seen is that the typical IPT candidate would be a patient who tends to feel exhausted and flu-like most of the time. In addition, their mood may tend to be on the depressed side. Laboratory analysis will generally show elevated viral antibodies, or they may have a positive PCR test demonstrating chronic viral infection, such as EBV, CMV, HHV-6, and others. ImmuneSupport.com: You emphasize a mind-bodyspirit approach to treatment. Please explain this approach a little and describe how its benefits exceed those of traditional medicine alone. HW: How would you describe the typical response of the patients treated? Bill Salt, M.D.: The last century has brought remarkable advances in biomedical technology and treatment. As a society, we have come to expect that effective treatments and cure should be available for many to most medical conditions. Yet, most of the symptoms, syndromes, and illnesses that people experience cannot be explained by organic disease identifiable by currently available medical tests and the biomedical model of illness, disease, healing, and health. Dr. Guyer: The patient reports, from a symptom perspective, include a generalized improvement in mood (sometimes even euphoria), a significant improvement in energy levels and the ability to do things they would not generally have been able to previously accomplish. Also, a decrease in overall body pain. As you might expect these real world improvements have been the most satisfying for the patient and myself. When a mother can take her children to Disney World on vacation for the first time, it is a transformative experience and increases the individual’s faith in their own health potential. Secondly, we see positive changes on lab analysis including resolution of positive PCR results and in antibody levels of viruses returning to normal. Additionally, immune system abnormalities will usually return to normal range. Most of these medically unexplained “functional” symptoms and illnesses are related to medical labeling (medicalization) of functional symptoms as functional syndromes (e.g., fibromyalgia and irritable bowel syndrome), stress and the stress response, the emotional brain and emotional distress, negative thinking and beliefs, and unhealthy lifestyle choices and behaviors. These factors also cause or contribute to serious diseases, such as insulin resistance syndrome (metabolic syndrome X). HW: Could you discuss some individual cases in a little detail which you have treated lately? The mind, brain and body, and gut cannot be Dr. Guyer: This could help personalize the approach and Continued on page 6 ImmuneSupport.com Continued on page 6 5 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Guyer, M.D., continued from page 5 Salt, M.D., Season, M.D., continued from page 5 give your readers a real sense of the human character and results of this treatment. A first patient is John. I initially saw him in 1999 for CFS and he had previously been to a number of other health care providers. We worked nutritionally with him for some time with good results, but he was unable to get over the “hump”(i.e., he had a 50-60% improvement, but did not return to a baseline state of health). separated. There is a scientific and neurobiologic basis of this Mind/Brain-Body Connection that is common to all healing traditions. Understanding homeostasis (internal stability), the stress response, the emotional brain, distinctions between treatment, cure, and healing, the placebo response, and our innate capacity for self-healing represents the intersection and convergent common ground of ancient, traditional, complementary, alternative, and Western biomedical approaches to health, disease, illness, and healing. He lives here in Indianapolis and works as a T.V. production technician at a local station. He has had about 12 treatments over all. Initially his EBV antibody was 25 times higher then normal and as you might expect he felt tired and flu-like all of the time. After six treatments he improved about 80%. The additional benefit with John was that his mental focusing and concentration came back and even comprehension of mathematical skills which have helped in his vocational obligations considerably. John also has mentioned a profound improvement in mood (no depression) and selfconfidence. Finally, empiric and scientific evidence continues to confirm that there is a spiritual dimension to the Mind/Brain Body Connection and that spirituality can be beneficial to health. In this regard, an inclusive term is the Mind/BrainBodySpirit Connection and MindBodySpirit medicine. ImmuneSupport.com: For many people - and for FM and CFS patients, stress can mean triggering a flare up of their symptoms and a subsequent setback in healing. What is your advice for managing stress when you are living with a chronic illness like FM and/or CFS? HW: So, the insulin has a therapeutic effect as well, in that it has been used historically to treat depression. Bill Salt, M.D.: Every one of us - doctors included! - must have a self-care plan. There are many paths to coping and healing, but our suggestions include, Dr. Guyer: Yes, the concept is similar, but obviously much less invasive, completely controlled and without side effects. One of our other IPT patients, Jan, who works in the pharmaceutical industry, has told me she feels like the insulin therapy seems to “clear her body out” of all the negative feedback. Somewhat like what happens with a computer that is malfunctioning and resumes function after being rebooted. She also improved significantly. • Learn all that you can about the Mind/BrainBodySpirit Connection. • Accept that emotional feelings, such as anxiety, depression, and negative thoughts can be triggered through the stress response and that they can aggravate and worsen your symptoms. Medical treatment is available, but you should know your options. HW: When Dennis Schoen, our CEO, visited your office in Indiana he met Dan, who was feeling great after just two treatments that week. • Reduce your allostatic load (bad stress response) through the consistent application of: Dr. Guyer: Dan is from Illinois and had worked as a chiropractor, but he had been out of work for several years due to CFS. - various relaxation techniques, such as breathing exercises, progressive relaxation, meditation, yoga and hypnosis HW: How is he doing now? - positive thinking and recognition of the harmful effects of negative thinking (cognitive behavioral techniques) Dr. Guyer: Like Dan mentioned to Dennis, he had done wonderfully after just two treatments and he is now back at work. Still he plans to return to our office in February for additional treatment. Overall, Dan had an exceptional response and with a little fine tuning I would expect he could regain normal function. - endurance (aerobic) exercise and stretching - healthy eating (it is usually more important to focus upon overall healthy eating than upon avoidance of suspected food and dietary triggers) HW: And you had a case from New York – a patient who had mixed viral infections and Babesia. - achieving and maintaining a healthy weight - obtaining adequate and restorative sleep Dr. Guyer: Yes, James was a young man who competed on his school’s crew team. Unfortunately, he no longer - avoiding unhealthy behaviors, such as smoking, heavy Continued on page 7 ImmuneSupport.com 6 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Salt, M.D., Season, M.D., continued from page 6 had been able to participate in crew because of CFS. In addition he would experience cyclic periods of a very high fever and severe headaches. His lab analysis did show antibodies for Babesia, and a PCR test showed mycoplasma pneumoniae and HHV-6 A. alcohol consumption, high demand/low control stressors, and social isolation • In order that you can work efficiently and effectively with doctors and other health professionals, learn about medical treatment options that may be helpful. However, the beauty of IPT is that it can be used to amplify any other types of treatment with which it is administered. Often we administer supplements such as Transfer Factor, NT Factor and intravenous vitamin therapy or bio-oxidative therapy along with IPT. In this case with James, we combined IPT with IV peroxide and ozone (MAH) with very good results. He is back to school now and doing well. I might add we have maintained him on NT factor and MycoPlus and he has not had headaches or fevers in a year now, his functioning is back and his labs have normalized. ImmuneSupport.com: What natural approaches for managing FM do you feel are most effective? Bill Salt, M.D.: Developing a self-care plan, which includes cognitive - behavioral therapy (positive thinking and understanding what fibromyalgia is and is not), exercise, healthy eating, and stress management. ImmuneSupport.com: What do you think of the newer pain drugs for FM - such as Ultracet and Milnacipran? Bill Salt, M.D.: Rather than focus upon specific drugs, we prefer to underscore the fact that scientists and physicians are working very hard to develop medicines that help to relieve symptoms of functional disorders, such as fibromyalgia and irritable bowel syndrome. But remember to respect the symptoms. All healing traditions teach that symptoms mean we are out of balance. HW: Do you think IPT can help a variety of illnesses? Dr. Guyer: Yes, I have even seen a case of a patient with Primary Sclerosing Cholangitis (being treated for CFS) whose liver functions have returned to normal! Initial results in a disease process such as this are encouraging. Primarily, much of the experience of IPT is with cancer treatment. But, there is also considerable historical usage with a broad array of medical problems ranging from chronic back pain, asthma, arthritis, autoimmune problems and depression, to name a few. I (Dr. Salt) experience all of the symptoms of fibromyalgia during periods of high stress, most commonly when “on call” at the hospital with an 80 to 90 hour work week and much sleep interruption by phone calls and emergencies. I work very hard on self-care to reduce the harmful effects of the stress response. Symptoms can also reflect other imbalances: emotional distress - including depression and repressed anger, and spiritual and existential issues - such as questions about life meaning and purpose. Life is a journey, and symptoms are guideposts. HW: What are the adjunctive treatments you are finding useful with these and other patients? Dr. Guyer: I must say I have really come to like NT Factor. I have been using this for almost all of our patients and I have found that it works wonders for energy levels especially if given at higher doses until you start to get the fatigue reduction results. Additionally, MycoPlus has been a great addition since I am finding many patients with CFS have coexisting mycoplasmal and nanobacterial infections that are noted on PCR testing. ImmuneSupport.com: Self-care for FM patients is crucial in the successful management of the disease. If you had to choose one single piece of advice to give FM patients along these lines, what would it be? HW: You mentioned using cellular extracts with great success recently. Are you still finding good results with these additional therapies? Bill Salt, M.D.: Regular endurance exercise. Final Comment: Dr. Guyer: Definitely. I would say using the Live Cell Therapy has been an enormous boon with our CFS/FM patients. Generally, we use Atrium Biologics products orally which I believe Pro Health will soon be carrying, and in addition, I have been using injectable Live Cell Extracts from France and Germany. The concept that functional symptoms and syndromes - such as fibromyalgia and irritable bowel syndrome - are linked to stress and emotion, does not imply that there is nothing wrong and the problem is imagined or “all in the head.” The symptoms and suffering reflect real illness and can be associated with significant impairment of life functioning and even disability. While emotional feelings and distress - such as anxiety and depression - may be generated through the same Mind/BrainBody Connection dysfunction, can contribute HW: Thank you again for keeping us updated on the cutting-edge treatments you are successfully using in your practice. We look forward to future treatment developments and follow-ups to the continued use of the Continued on page 8 ImmuneSupport.com Continued on page 8 7 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Guyer, M.D., continued from page 7 Salt, M.D., Season, M.D., continued from page 7 therapies you have discussed here. to the symptom experience and illness, and can require treatment, the fundamental problem is not psychiatric and is “not all in the head.” Dr. Guyer: As always, I am happy if what I can share helps and encourages those with CFS/FMS. We both have seen that often many patients get discouraged by their doctors and the medical profession in general. If there is any single piece of advice I could give, it would be to keep the faith and keep searching with an open mind. Your answers are out there and all it takes is persistence and faith, and always trust your intuition. I have found it to be the most successful guide in my work with patients. They generally have a sense of what is the “right” path of healing for them. The book “Fibromyalgia and the MindBodySpirit Connection,” by William B. Salt II, MD and Edwin H. Season, MD can be obtained by calling (614) 445-4949. It is also available in bookstores and on the Internet at www.parkviewpub.com, www.amazon.com, and www.barnesandnoble.com. HW HW editor’s note: I encourage any patients who have undergone IPT treatment (as with any other traditional and alternative therapies tried) to share their experience with other patients on our message boards and chat rooms in the community area of ImmuneSupport.com, at http://www.ImmuneSupport.com/chat/. If you are interested in learning more about IPT and Dr. Guyer and the Advanced Medical Center, please visit: www.daleguyermd.com. HW Shames, M.D., continued from page 1 releases the mitochondria for the lion’s share of every cell’s energy. This information was tucked away until well after medical school, when my wife Karilee had a recurrence of her Hashimoto’s problem at the birth of our second child. I was amazed to see how many symptoms - and how much mischief - could be caused by a malfunctioning thyroid gland. Karilee was so exhausted she couldn’t get out of bed! We have been doing the “thyroid dance” ever since. In fact, all 3 of our children tested positive for thyroid at puberty. ImmuneSupport.com: What are some of the primary symptoms of thyroid dysfunction? Dr. Shames: There is a huge list of possible thyroid symptoms. Some people have one or more, some have many. They can be anything from fatigue, depression, overweight, dry hair, skin and eyes; low blood pressure, high cholesterol, aches and pains for no reason, and a whole host of female problems, including bad periods or PMS, infertility, difficult menopause, low libido (in men also) as well as constipation...and the list goes on. www.ImmuneSupport.com ImmuneSupport.com: Do you treat any Chronic Fatigue Syndrome and/or fibromyalgia patients? With both types of patient, whose symptoms frequently overlap, thyroid and adrenal problems are common and cause very low energy as well as adrenal burnout in some cases. Please describe how you go about diagnosing thyroid problems in CFS and FM patients and how you treat them. Your CFS & Fibromyalgia Health Resource • Chat rooms • Message boards • Doctors & support group listings Dr. Shames: I see both kinds of situations regularly in my San Rafael, CA office. There appears to be a wide overlap; one thing is quite common between them. Both of these medical conditions are intimately involved with thyroid and adrenal dysfunction. I treat them by first isolating for a thyroid problem, and treating that first. Then, once thyroid is as stable as we can get it, I check for and treat adrenal imbalance. • Hundreds of specialty products • Thousands of articles & abstracts • Much more! Many people are frustrated in dealing with the hormonal balance difficulty because they don’t Continued on page 9 ImmuneSupport.com 8 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Shames, M.D., continued from page 8 Healing Chronic Illness at Home: Oxygen, Ozone, Sauna and Detoxification for Lyme Disease, Fibromyalgia, Chronic Fatigue Syndrome and MCS isolate and treat the thyroid issue first. Thyroid is somewhat prominent and preemptory, it is primary among the endocrine glands, since it is the gas pedal for everything else. If you try to treat the adrenal imbalance first, in my experience, you can make the system further imbalanced, more difficult to diagnose properly, and success becomes more elusive. By Jill Neimark with Byron White, N.D. There is one situation, however, where thyroid and adrenal rebalancing need to take place concurrently. This occurs when the adrenal balance is severe and co-exists in tandem with a thyroid imbalance. In these situations, the procedure is to correct the thyroid a little, then correct for adrenal a little, then go back and correct a bit more for thyroid, then a bit more with adrenal corrections. The reason for this dual upward titration is that treating either one of these insufficiencies can “unmask” and exacerbate the insufficiency symptom of the other. Jill Neimark is an author and journalist who writes frequently on health and science for national publications. Ms. Neimark is also a lyme patient. Byron White, N.D., is a naturopath who suffers from lyme disease and employs a variety of home-based therapies to successfully manage chronic illness. Three and a half years ago, on a pleasant June afternoon, my life plunged off a cliff into free fall. I walked in a Connecticut garden and twelve days later had a big bull’s-eye rash on the back of my knee and a classic case of lyme disease. Even though I went on antibiotics at once, I slid into a nightmare of ill health. Antibiotics stemmed, but did not kill, the infection. As the spirochete relentlessly invaded my nerve tissue, I felt as if electronic buzzers were being pushed incessantly throughout my body. I suffered from vertigo, terrible thirst, and incredible pain in my neck and back. I was also crushed by a fatigue so profound I figured if it lasted, I’d eventually waste away and die. Most of the time, however, this is not the case. Even if low thyroid and low adrenal coexist, frequently correction of the thyroid alone will then throttle the rest of the body, including the adrenal gland, back into some semblance of normal function. Thus, many CFIDS and FM sufferers get a jump-start on their recovery process via careful and rigorous thyroid treatment first. To accurately diagnose a thyroid problem is crucial. We cannot simply rely on TSH and or Free T4 blood tests, even though this is the industry standard. Instead, we need to do a more complete panel of blood tests, which would include Total T3, Free T3, and thyroid antibodies. In addition to blood tests, we must also include the equally important basal body temperature evaluation, and family history. For more details, I recommend that anyone with CFS or FM look at this issue very carefully. The details of diagnosis and treatment are clearly defined in our book THYROID POWER: 10 STEPS TO TOTAL HEALTH (HarperCollins, 2001). Thus began an odyssey that has not yet ended although I am improving steadily and without using antibiotics. In the course of research, I met and befriended a knowledgeable naturopath who suffers from lyme himself, Dr. Byron White. Together we have put together an approach to healing therapies that you can do at home—all of which should be monitored by your doctor, of course. These therapies are intended to restore oxygen to hypoxic cells, kill pathogens, help detox the liver, colon and entire body, and use hyperthermia to improve immune function and metabolism and help the body sweat out toxins. These profound healing therapies employ both age-old naturopathic techniques and stateof-the-art modern tools, and they are ideal for the chemically sensitive who cannot tolerate drugs. What is often missed, especially in CFS or FM patients, is the critical four columns of a “temple of diagnosis” (see visual of this on our website www.ThyroidPower.com in cartoons for step 3) that includes using signs and symptoms, family history, associated conditions AS WELL AS blood testing. A hand-tailored approach in our own homes allows us to move from illness to health slowly, carefully, and with needed rest and ease. “It is important to fit the treatment to the person and not the person to the treatment,” explains Dr. White. Each person’s body goes through a natural building and detoxification cycle as it heals. ImmuneSupport.com: Do you use any alternative therapy methods for improving thyroid function in patients? Dr. Shames: Absolutely - this is a critical part of how I work. I have been involved in holistic medical care for almost 30 years. I often use relaxation therapies and hypnotic techniques, and teach them to my patients. I also send them to receive a great variety of therapies, HEALING AT HOME: THREE ESSENTIAL POINTS Before you begin a healing journey, it’s important to know that: Continued on page 10 ImmuneSupport.com Continued on page 10 9 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Neimark, White, N.D., continued from page 9 Shames, M.D., continued from page 9 1) No matter how bad it gets, you can get better. 2) Patience is key, because each body is different, and you must allow yourself time for trial and error, and for cycles of improvement as well as mistakes and setbacks. Think of yourself on a treasure hunt, picking up clues along the way. 3) If possible, seek therapies you can do at home in your own time, and on your own schedule, while listening to your body’s responses and discussing them with a trusted medical practitioner who will be your guide in healing. depending largely upon a number of factors, such as what they believe has been helpful, their ability to pay, etc. I recommend massage, energy healing or touch therapies, nutritional therapies, biofeedback, visualization and imagery, yoga, chi gung, and lots of fun and healthy exercise when they feel better! These are selected individually depending on who practices in the various areas. In fact, I provide thyroid coaching for people over the phone, and have the opportunity to “meet” people from all over the US and beyond. I help them to gather the proper materials and family history, seek the best possible testing (some is home-based, such as saliva testing), then learn to advocate better for better health care from their providers. I also do my best to help people from various locations to connect with practitioners in their area who are more open and “thyroid-friendly”. HYPERBARIC OXYGEN: Restoring The Entire Body The first therapy that both Dr. White and I use is hyperbaric oxygen. We both own portable hyperbaric oxygen chambers that have made a significant difference in our health. These home chambers are approved by the FDA, are available by prescription from your doctor, and pressurize to low, safe levels—4.5 psi, or about 10 feet below sea level. They are often called “mild” hyperbaric oxygen chambers. With the use of an oxygen concentrator and a medical pass-through, they can increase tissue oxygen levels up to 400%. Karilee, who is a holistic nurse, and I have been teaching seminars to health practitioners on Thyroid Power, so we are continuing to develop our practitioner database for various alternative and complementary therapies, as well as for physicians. We have also been moving more in the direction of home-based testing, so those whose pocketbooks or physical situation (or beliefs) allow them to work with these less medical, less standard, and less approved methods. Some people are having tremendous success using saliva and urine testing for thyroid and other concerns. Hyperbaric oxygen treatments trigger a marked increase in the ability of white blood cells to destroy bacteria, help new blood vessels grow, saturate tissues with healing oxygen that helps stop damage from toxins and inhibits the growth of anaerobic bacteria. They also improve brain function. One specialist in mild hyperbaric therapy, Gunnar Heuser, M.D., Ph.D., found that using these chambers, circulation and blood flow improved in the brain (using specializing scanning imagery), after only ten sessions. Rhett Bergeron, M.D. offers mild hyperbaric for patients in his two clinics outside Atlanta, Georgia. Most individuals with chronic illness suffer from hypoxia, he notes. “I have found that patients respond extremely favorably to the hyperbaric treatments,” says Dr. Bergeron. “Mild hyperbaric has been shown to be just as effective as treatments at greater pressures and the patients like how it makes them feel.” ImmuneSupport.com: How do you believe Omega-3 fatty acids and multivitamin supplements support and promote optimal thyroid function? Dr. Shames: The thyroid is the gas pedal for your body’s energy flow, but you need fuel and spark for the gas pedal to accomplish anything. Fuel would be optimal nutrients, and supplements add the spark. There are certain steps in the production and utilization of thyroid hormone that require specific nutrients in quantities that many people do not have. For instance, let’s consider the conversion of inactive T4 in the body. T4 is made by thyroid gland and transported in bloodstream or taken by synthetic pills, but is inactive in the body. It has to be converted to T3 . This conversion of T4 to T3 is dependent on a 5’ (prime) deiodinase enzyme. It turns out this enzyme is selenium dependent, so without selenium, it is hard to get active thyroid hormone. The first hyperbaric chamber in medicine was made by a British physician in 1662. However, hyperbaric treatments just recently became available for home use in a portable chamber. I learned about portable chambers through Lance Brubaker, who was diagnosed with lyme in 1990 and now works with Dr. Bergeron. I had benefited from hyperbaric at much higher pressures in clinics, but the cost was prohibitive, and I hated having to relocate to get my treatments, and I never was able to take off enough time to make a long-lasting Omega-3 fatty acids are helpful for inflammation (and thyroiditis has inflammation in the production phase). The omegas help to reduce this inflammation. Also, the receptor site on the lipid protein layer of the cell Continued on page 11 ImmuneSupport.com 10 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Shames, M.D., continued from page 10 difference in my health. surface seems to be enhanced with the addition of omega fatty acids to the diet. A good multivitamin provides a variety of the other nutrients known to be just as crucial, such as selenium, in other pathway bottlenecks. Thyroid status is controlled at seven different hierarchical levels in the body; this is more control than any other process, and taking key vitamins and co-factors will help to ensure proper function at each level. According to Lance, at his sickest, “I literally couldn’t walk 200 feet without passing out. I had countless disassociated symptoms, some life-threatening.” In 1994, he shut down his business and built his own home hyperbaric chamber. “I did hyperbaric three times a week for two months, and two times a week after that for two years. I also added in a low temperature sauna protocol, and did a lot of cleansing and detox.” Today, Lance is fully recovered. Last summer, at Lance’s invitation, I visited Dr. Bergeron’s clinic, tried just two sessions in the portable chamber and was delighted to feel improvement in energy and muscle strength, as well as lessening of the buzzing static that seems to accompany lyme, and that author Amy Tan (who suffers from late stage lyme) has called, “Dolby digital syndrome.” (I also got a look at Lance’s old chamber, which sits like a proud relic in his garage, a testament to his ingenuity and pure guts, as the thing is built out of butane tank and submarine hatch and has no windows. Today he has a state-of-the-art portable chamber in one of his extra bedrooms and still uses it if he feels a cold coming on or wants a tune-up.) ImmuneSupport.com: What traditional medicine approaches do you use to treat patients with thyroid problems? Dr. Shames: When practicing only using traditional medicine, I use thyroid hormone pills, and I monitor the results with blood tests and basal temperatures. This standard approach, when combined with the alternatives mentioned above, is your best shot at full thyroid recovery. ImmuneSupport.com: Do you think there is frequent misdiagnosis in the CFS patient population that could prevent thyroid problems among these patients from being properly treated? Before my home chamber I was suffering excruciating headaches that I call “lymegraines”—they were clobbering me once or twice a week. Since getting my chamber last July, the headaches have vanished. My energy, digestion and sleep are improved. But perhaps the greatest benefit is how I feel in the chamber: as if all my neurons, which had been unhitched and cut and were just dangling and doing the jitterbug, have been reconnected and are working properly. I even drift off to sleep at times. So, oddly, it has become my favorite place—a kind of womb of feel-good safety. I use my chamber about twice a week. Dr. Shames: Absolutely! Many of the thyroid symptoms are wrongly considered to be part of the CFS problem. Also many of the symptoms are similar. In fact, some people don’t have a thyroid problem until they have the immune system compromised from CFS, then the thyroid can go downhill. The thyroid is easy to treat compared to many aspects of CFS and FM, so it should be handled first. ImmuneSupport.com: What issues are you addressing in your new book? Dr. Shames: In our upcoming project, we are moving beyond strict thyroid care into a more holistic approach to thyroid, adrenal, and reproductive hormone balance. My response to the chamber is typical, according to Dr. Ignacio Fojgel, M.D., Founder & Head of the Complementary & Integrative Medicine Department at Maimonides University in Argentina, and Chief of the Hyperbaric Medicine Unit there. “The action of pressure on the autonomic nervous system has never been given its due attention. Many people sleep during the session or become relaxed and peaceful. Parasympathetic upregulation occurs, and a relatively high parasympathetic tone is needed for most healing processes to happen.” In fact, in chronic illness, the sympathetic nervous system is often dominant and can trigger nervousness, agitation, hyperactivity, sleep difficulties, and dysregulation of hormones and neurotransmitters. Hyperbaric treatment helps restore balance. After 30 years of practice, we have come up with a step-by-step process to work with these issues, and to help people uncover the roots of their health issues, one step at a time. We believe in slow, careful, methodical care that allows us to unpeel the layers of your condition, addressing them carefully and moving slowly enough that we don’t unmask other related conditions, thereby further muddying the waters. While we know that most people in our society are accustomed to fast food and fast medicine, we believe these underlying difficult to diagnose energy problems must be addressed carefully for optimal results. Barbara Kris, a 60 year old from North Carolina, suffers from post-polio syndrome and lupus, and nearly died a year ago from necrotizing fascitis, pneumonia and heart failure. Daily home treatments with hyperbaric ImmuneSupport.com: What is your advice to patients struggling with debilitating fatigue? Continued on page 12 ImmuneSupport.com Continued on page 12 11 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Neimark, White, N.D., continued from page 11 Shames, M.D., continued from page 11 oxygen, along with alternative therapies like chelation and glutathione, have brought her back to a normal life. “People tell me it’s miraculous. A year ago the weakness in my legs was so bad I couldn’t get up from a chair, and my doctor tells me without the hyperbaric treatments I would probably have lost my hand. I am thoroughly grateful and I would not be without my chamber.” Dr. Shames: My heartfelt advice to people struggling with CFS or fibromyalgia conditions is to do everything possible for diagnosis and treatment of a possible co-existent thyroid insufficiency. This will make the remedies and procedures for CFS and FM more effective, and more long-lasting. We’re not saying that CFS or FM are really being misdiagnosed; there are indeed some people who are truly thyro-compromised and diagnosed with CFS; when they are treated for the underlying thyroid problem, many of their symptoms, sometimes all of them, improve. For most others, however, the thyroid problem co-exists with the CFS/FM syndromes, and can help people to begin to feel better, so they then are more able to address the other more complex concerns. Our Bottom Line: Remember - YOU CAN STILL BE LOW THYROID, EVEN WITH NORMAL TESTS. Treat the thyroid first! With a home chamber you can calibrate your treatment to your schedule and need. You can also do treatments over a period of months and years, rather than a brief stay at a clinic. “When I first began hyperbaric,” says Dr. White, “I started with very low pressure and no additional oxygen. I was severely deconditioned from illness and twenty minutes was all my body wanted. As my body began to function at a higher level, it began to push out excess carbon monoxide. One of the things your body will do when it gets more oxygen, and thus more energy, is to begin to detox.” Over a period of months he built up to higher pressures and added in more oxygen, and watched neuropathic pain slowly vanish, while fatigue, balance and memory problems improved. Richard Shames, M.D., and Karilee Shames, Ph.D., R.N., are the authors of THYROID POWER: 10 STEPS TO TOTAL HEALTH (HarperCollins 2001) now available in paperback. This book can be purchased at www.amazon.com, www.barnesandnoble.com and at bookstores. HW There are other methods that may increase oxygen levels although the honest truth is, they are not nearly as powerful as they do not push oxygen into the tissues. Still, we know of one lyme patient who breathes in oxygen through a cannula while increasing his circulation by sitting in a hot bath. For those who are well enough, light exercise on a treadmill or stationery bicycle while breathing in oxygen is also helpful. Finally, one bedridden patient took an oxygen supplement called DiOxychlor along with a supplement called nattokinase, which helps clear fibrin from the blood and allow nutrients to access cells more readily. She noticed improvement after combining the two supplements (today, with many alternative therapy interventions she is 90% improved). fungidical, protozoacidal and virucidal. In short, it is a strong germicide. It also oxidizes toxins, certain metals, and pesticides—breaking them down so the body can excrete them (with help from naturopathic techniques which we will explain shortly). Ozone works as a free-radical. Our own neutrophils, which kill pathogens, actually manufacture ozone, according to recent research by the Scripps Institute. "Neutrophils are very small cells, but they are very nasty microbicidal agents," says Bernard Babior, professor at The Scripps Research Institute (TSRI) and an expert in neutrophils, which he has been studying for over 30 years. "An active neutrophil kills a bacterium in only a few seconds, using at least a dozen and a half mechanisms." Apparently the neutrophils feed singlet oxygen (01) to antibodies, which convert it to 03 and use it to poke holes in pathogens and kill them. OZONE: Killing Pathogens and Oxygenating Cells Although at times I feel evangelistic about my chamber, I know it is not a silver-bullet. In fact, there is no silver bullet in chronic illness, because it is a multisystemic breakdown. Usually a person with CFIDS, fibromyalgia, lyme, lupus, or any such chronic disorder has a number of chronic infections and toxic overload. “I tested positive for h. pylori four years ago and was suffering from gastritis and severe abdominal pain,” recalls Dr. White. “I drank four glasses of ozonated water daily for a month and my symptoms cleared up. When I was re-tested I was negative.” Dr. White also utilizes ozonal, ozone pumped through olive oil, in order to treat sinus and bronchial infection. This is considered safe to breathe. A great pioneer in ozone therapy is chiropractor Saul Pressman, of Vancouver. He grew up on a farm and unwittingly poisoned himself with pesticides several Another oxygen therapy that both Dr. White and I use is ozone, or 03. Ozone is known to be bactericidal, ImmuneSupport.com 12 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 times. “I developed fibromyalgia so bad that by age 33 I had to go on all fours to go up and down stairs,” he recalls. Adopting a naturopathic approach, he learned he had celiac disease and eliminated all gluten products, which improved his health. He also began to use ozone. Today he is completely healthy. “Now I am 50 and run up stairs two at a time.” time from the most recent to the oldest symptoms. Carlos LeClair considers himself well today: he has had no symptoms of lyme disease in the last two years. Ken Gullan, Director of the Institute for Research Integration (IRI) in San Diego, CA, has used ozone saunas for 18 months to eliminate asbestos poisoning from three years when he worked for a mining business in Africa. When he began the saunas, he had mild prostatitis, athlete’s foot, fatigue, and above all, over 450 fatty tumors called lipomas all over his body. “I used to joke that I looked like a bunch of grapes in a pair of pantyhose.” The lipomas were probably the body’s attempt to safely surround asbestos fibers with fatty tumors. “Initially I got a really bad rash. It seemed like I couldn’t detox any other way than out through the skin.” Today, his prostatitis is gone, his athlete’s foot has disappeared, and he has about 160 lipomas left. “I’ve got an incredible amount of energy now, I believe that is the biggest overall benefit.” In Saul’s world, ozone is forever—rather than diamonds, for the story his wife told me is half fairy-tale and half healing odyssey. Years ago, Sherri-Lee Pressman had chronic fatigue and fibromyalgia so extreme she was on disability. “I couldn’t lift my arms for the pain. I’d take a shower and be so exhausted I had to lie down and rest for an hour.” Determined to get well, she worked with a naturopath and over time recovered about 75%, returned to work, and met Saul Pressman. Three weeks later, for Christmas, he gave her an ozone generator. “I was really blown away,” she recalls. “I knew what it meant to him.” Another three weeks passed and he asked her to marry him; he also suggested she take time off and really heal herself with ozone. “I used it every day. It was intense, and it often made me feel like I had the flu, but I kept at it. I wanted to completely heal so I could get pregnant.” Slowly but surely she recovered total health, her chronic yeast infections vanished, robust good energy returned, and today they have a healthy daughter. I myself am at the beginning of my ozone therapy experiment. I have tried the sauna four times and found myself in an energized and peaceful state afterwards. I am about to embark on a more regular protocol, hoping that by combining it with my hyperbaric oxygen chamber, I will provide my body with a truly powerful two-pronged healing therapy that allows my cells to breathe (oxygen) and helps them kill pathogens (ozone). Ozone can be taken into the body through insufflation (gas that is infused for a few minutes either into the ear, the rectum, or the vagina), by ozonating water and drinking it, by ozonating olive oil and applying it topically, by using a funnel to ozonate a specific part of the body, or by using an ozone steam sauna, which is perhaps the most powerful method. These saunas utilize a fiberglass steam cabinet where you sit comfortably inside the cabinet up to your neck, with your head in the open air. HYPERTHERMIA: How Saunas Can Heal A third very powerful modality that can be carried out at home is sauna therapy. Human exposure to toxins has dramatically increased in the last century, and their residues can be reduced through sauna therapy. In addition, sauna increases circulation and improves lymph flow. By allowing the body to eliminate toxins through the skin, sauna therapy helps the liver, kidneys, and bowel. As you sit in the sauna, your body temperature goes up, mimicking the natural fever response—which boosts the immune system. Carlos LeClair, a 73-year-old living in Florida, is convinced that ozone saunas eliminated his lyme disease symptoms when 24 months of antibiotics did not. Like many who use ozone saunas, he developed a rash. It is thought that the rash is part of a detox reaction, since continued use of ozone results in fading of the rash, according to Pressman. LeClair agrees. “I am absolutely convinced that the itchiness and rash I experienced, mainly on my chest, was due to an interaction of the ozone with toxins in my body. The rash was gone after eight months of ozone saunas. When I had completed twelve months, twice a week, I decided to do a 30-minute sauna every day for ten days, just to make sure that I had finished off the lyme bug. By the sixth consecutive day of ozone saunas I woke up to find a 3-inch diameter bull’s-eye rash over my left kidney.” The bull’s-eye rash is unique among rashes and diagnostic of lyme disease all by itself. In naturopathic parlance, this bull’s-eye would be called ‘retracing’—an illness peels back symptomatically over Sauna therapy can be done at home. Dr. White has a top of the line Healthmate Far Infrared Sauna, while I have a very inexpensive near infrared bulb sauna designed by naturopath Larry Wilson. Others use far infrared heat lamps. Although there is much debate about the benefits Continued on page 14 ImmuneSupport.com 13 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Neimark, White, N.D., continued from page 13 of different types of saunas, and the depth that various forms of infrared penetrate into the body, we feel that most forms of sauna, used carefully, are helpful. Infrared saunas are easier to tolerate because they tend to heat the body and not the air, allowing people to tolerate much longer sauna time and achieve the same results. As mentioned previously, Lance Brubaker melded hyperbaric and sauna therapy to heal himself. “Spirochetes don’t like pressure, oxygen, or heat, so I offered them all three,” he recalls. Tissue oxygen levels remain elevated for hours after a hyperbaric chamber session, and the infrared sauna heat increases circulation and stimulates the immune system. The two can be synergistic. so dizzy, am using my walking frame less and managing to stay vertical for hours every day. I also had a blood test and the nurse used an adult needle and managed to get a whole vial of blood. This is one of the best things I’ve done for my health in years. I am feeling a lot more optimistic about getting well. My stamina is much better and I'm managing to do all sorts of things I haven't felt like doing for years. I am recommending it to many other chronic lymies and CFS patients, who are being told there is nothing they can do about their neurally-mediated hypotension. The bulb sauna is working wonders for me.” The length of time spent in the sauna varies with each individual. Most chronically ill individuals should start with about 10 minutes, and see how that impacts them over the next 24-48 hours. I overdid my sauna therapy in the beginning, staying in for 45 minutes and experienced an increase in muscle pain as a result. After Dr. Wilson performed hair mineral analysis on me he advised me to reduce my sauna to 20 minutes every other day. Building the body up and detoxifying at the same time are crucial to successfully improving a person’s health. “It is common to find people with chronic illness that have compromised ability to detoxify,” explains Dr. White. “Generally, the chronically ill body is in an acid state. It can be useful to eat and juice foods that are alkaline to help decrease acidity. These include any green vegetables, especially the leafy ones; as well as figs, lima beans, apricots, spinach and lemons.” DETOXIFICATION: Last But Not Least The colon, liver and kidneys are the most common routes of detoxification, but your lungs, lymph and skin can also rid the body of waste. “Most people I have worked with have very sluggish or stagnant lymph systems,” says Dr. White. To detox at home, drink clean water, along with electrolytes on a daily basis. Try to drink half your body weight in ounces, so if you weigh 100 pounds, try to drink 50 ounces over the course of the day. An electrolyte formula Dr. White recommends is E-Lyte. “Your whole body depends on water and minerals to function. I also recommend dry brush massage to encourage lymph flow.” “It is important to temper treatments like hyperbaric oxygen, ozone and sauna with your body’s ability to handle the treatment,” notes Dr. White. Colon cleansing, via enemas, home colemas, or professional colonics, can also be useful. Dr. White recommends a 48-ounce plastic enema bucket for those new to colon cleansing, rather than an enema bag (the latter are usually made out of rubber, a petroleum product). Liver flushes (using various formulas) can also decrease toxic load on the body by helping clear the liver and gallbladder of stones and sludge. Carlos LeClair recalls being advised to do liver flushes with ozone, and in retrospect, “I wish I had followed the advice derived from others' experiences and thoroughly flushed out my liver before beginning the saunas. I believe that if I had done this, the rash might not have lasted so long.” Rosemary Trudeau, an Australian woman who has been ill with some form of CFIDS or possibly lyme for 24 years, reports the bulb sauna has normalized her blood pressure for the first time in decades. “The first time I used the sauna,” she recalls, “I only coped with 5 minutes and then had to crawl into bed. Since then I have built up the time to twenty minutes, a ten minute rest, and another twenty minutes. My blood pressure had been 80/60 for twenty years. After ten weeks my blood pressure is up to 110/70. I am not ImmuneSupport.com Herbal support can also be useful. Two herbs that are receiving a lot of attention in the lyme and CFIDS community lately are artemisinin and samento. The former is a derivative of artemisia that is said to be useful in a tickborne infection called babesia. It also has a history in Chinese medicine of being antispirochetal. In addition, it is antifungal. The latter, samento, is a form of cat’s claw that seems to be immune modulating and 14 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 PRO HEALTH SCIENTIFIC ADVISORY BOARD antibacterial. It is wise to enlist the aid of a health care practitioner who is familiar with these procedures and herbs to help design a program of detoxification that is gentle but thorough. “As you heal and work on yourself it will be natural to have days that are worse and better,” explains Dr. White. “It is also common to have emotional responses triggered by the healing and detoxification cycles. It is natural to release what I call emotional toxins as well as physical toxins through this process. That gives us an opportunity to grow and heal in new ways.” Robert Bennett, M.D., Ph.D. Oregon Health and Science University, Portland, Oregon Jay A. Goldstein, M.D. Former Director, The Chronic Fatigue Syndrome Institute, Anaheim Hills, California Charles W. Lapp, M.D. Director, Hunter-Hopkins Center, P.A., Medical Consultations, Charlotte, North Carolina; Consulting Professor, Duke University Medical Center As emotional, and even spiritual issues, come to the surface, it is important to keep a positive attitude. One of the best books on healing through the power of the mind is available free on the web via download. Called Your Empowering Spirit (Y.E.S.), by Gary Sinclair, it is an inspiring book about healing from the inside out. Sinclair claims to have healed himself of severe multiple sclerosis. William Maguire, M.D., Ph.D. Harvard Medical School, New York Medical College Kenny De Meirleir, M.D., Ph.D. REFERENCES: Vrije Universiteit Brussel, Brussels, Belgium -Mild Portable Hyperbaric Chamber: Vita02, www.Vita02.com, Lance Brubaker, (706) 265-7449. Home chambers come in three sizes, and leasing plans are available. -Ozone Sauna: Dr. Saul Pressman, DCh, Plasmafire International, www.plasmafire.com or call (604) 5329596. Dr. Pressman is widely considered to have the most reliable, high quality ozone products available. -Yahoo Groups: mild hyperbaric and lyme disease: http:// health.groups.yahoo.com/group/lyme-mildhyperbaric/; ozonetherapy: http://health.groups.yahoo.com/group/ ozonetherapy/ -Infrared Bulb Sauna: Dr. Larry Wilson, email: [email protected] or call (928) 445-7690. Dr. Wilson also sells a book, Manual of Sauna Therapy, that is very useful, at www.drlwilson.com. -Far Infrared Lamps: http://www.ycyhealth.com/tdp_ index.shtml -Enema Bucket: http://shop.store.yahoo.com/ homecareessentials/ppi2562.html -Colema Board: http://store.awwwsome.com/ enema.html -Gary Sinclair’s Your Empowering Spirit: http:// www.cyberphysiology.com/ or call (760) 451-3099 Daniel Peterson, M.D. Email contact for Byron White, N.D.: naturalhealthcare_ [email protected]. HW supplements intended solely for nutritional support. Sierra Internal CFS Center, Incline, Nevada Jacob Teitelbaum, M.D. National Research Center, Annapolis, Maryland HEALTHwatch is published by: Pro Health, Inc., 2040 Alameda Padre Serra, Suite 101, Santa Barbara, CA 93103. 1-800-366-6056 Editor: Lee Ann Stiff Design: Jon Poole Disclaimer: HEALTHwatch is published for individuals, health professionals and others interested in CFS and Fibromyalgia. Any nutritional supplements discussed in HEALTHwatch are not intended to diagnose, treat, cure, or prevent a disease, but rather are dietary © 2004 HEALTHwatch For permission to reproduce any of the information contained in this publication, please contact the Editor at: [email protected]. ImmuneSupport.com 15 1.800.366.6056 PRO HEALTH’S CHRONIC FATIGUE SYNDROME & FIBROMYALGIA NEWSLETTER 2004 VOLUME XIII, NO.1 Your Support at Work in The CFS/FM Community Fifteen Years and Counting, Pro Health is Your Complete CFS & FM Resource Empower Yourself! We are proud and thankful to be celebrating our 15 year anniversary – a great landmark in our mission to be the premier source for health-related information, comprehensive treatment solutions and patient advocacy that empowers people to take control of their health. Specialty Products to Fit Your Needs Over the years, we’ve fine tuned our selection of products in response to customer needs. 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