Fact Sheet Array BioPharma
Transcription
Fact Sheet Array BioPharma
Fact Sheet Array BioPharma In the News About Array BioPharma 2/1/16 Array initiates Immuno‐Oncology research collaboration with Dana Farber Cancer Institute Array BioPharma Inc. is a biopharmaceutical 12/16/15 Array announces Phase 3 binimetinib trial meets primary endpoint for NRAS‐mutant melanoma 11/16/15 Array and Pierre Fabre announce collaboration for Binimetinib and Encorafenib Analysts Mara Goldstein Cantor Fitzgerald NASDAQ ARRY company focused on the discovery, Stock Price (2/9/16) $2.50 development and commercialization of Market Capitalization $357.5 million 52 Week Range $2.50‐8.59 Shares Outstanding 143 million cancer drugs. These programs include R&D Staff 100 binimetinib , encorafenib and selumetinib Cash (12/31/15) $185.4 million (partnered with AstraZeneca). Headquarters Boulder, CO targeted small molecule drugs to treat patients afflicted with cancer. Six phase 3 studies are currently advancing related to three Path to Commercialization Upcoming Catalysts for Array Eun Yang Jeffries & Co. Anupam Rama JP Morgan Michael Schmidt Leerink Swann Ted Tenthoff Piper Jaffray Stephen Willey Stifel Nicolaus Matthew Andrews Wells Fargo Major Shareholders Redmile Group, LLC Fidelity Management & Research OrbiMed Advisors, LLC Deerfield Management Co., L.P. Biotechnology Value Fund, Inc. BlackRock Inst’l Trust Co., N.A. T. Rowe Price Associates, Inc. Vanguard Group, Inc. State Street Global Advisors (US) Baker Bros .Advisors, LP Pinnacle Associates, Ltd. MILO: MEK Inhibitor in Low Grade Serous Ovarian Cancer; NEMO: NRAS melanoma and MEK inhibitor; COLUMBUS: Combination of LGX818 used with MEK162 in BRAF mutant unresectable skin cancer; ASTRA: Pivotal trial in differentiated thyroid cancer; SELECT-1: selumetinib + docetaxel in patients with KRAS NCSLC Strategy We are building a fully‐integrated, commercial‐stage biopharmaceutical company that discovers, develops and markets safe and effective small molecule drugs to treat patients afflicted with cancer. We intend to accomplish this through the following strategies: • Invent targeted small molecule drugs that are either first‐in‐class or second generation drugs that have little or no competition, or demonstrate a competitive advantage over drugs currently on the market or in clinical development. • Develop and commercialize our drugs to maximize their overall value. As our first drug nears approval, we plan to build a therapeutically‐focused sales force to commercialize or co‐promote drugs we wholly own, or for which we retain development rights in major geographic areas. • Implement a partnering strategy in which we out‐license drugs outside our therapeutic or geographic focus and partner select early‐stage programs for continued research and development to receive research funding plus significant milestone payments and royalties. Array’s Top Priority Binimetinib & Encorafenib Development & Commercialization Board of Directors Executive Team Ron Squarer CEO Ron Squarer CEO Charles M. Baum, M.D., Ph.D. President & CEO, Mirati Therapeutics Dave Horin Interim CFO Gwen A. Fyfe, M.D. Independent Consultant Genentech* Kimberly Pope VP Human Resources Kyle A. Lefkoff Chairman Boulder Ventures John A. Orwin CEO Relypsa John R. Moore VP & General Counsel Selected Collaborators AstraZeneca Biogen Idec Celgene Genentech/Roche Oncothyreon Pierre Fabre Andrew Robbins COO Nick Saccomano, Ph.D. CSO Victor Sandor, M.D. CMO Gil J. Van Lunsen KPMG* *prior employers 3200 Walnut Street Boulder, Colorado 80301 Phone: 303.381.6600 Fax: 303.381.1390 www.arraybiopharma.com [email protected] Safe Harbor Statement: This document contains forward‐looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 that involve significant risks and uncertainties, including those discussed in our annual report filed on Form 10‐K for the fiscal year ended June 30, 2015, and in other reports filed by Array with the Securities and Exchange Commission. In addition, we may make forward‐looking statements in our press releases or in other oral or written communications with the public. These statements do not relate to historical matters and reflect our current expectations concerning future events. Therefore our actual results could differ materially from those anticipated in these forward‐looking statements as a result of many factors. These factors include, but are not limited to, our ability to continue to fund and successfully progress internal research efforts and to create effective, commercially viable drugs, our ability to achieve and maintain profitability, the extent to which the pharmaceutical and biotechnology industries are willing to in‐license drug candidates for their product pipelines and to collaborate with and fund third parties on their drug discovery activities, our ability to out‐license our proprietary candidates on favorable terms, risks associated with our dependence on our collaborators for the clinical development and commercialization of our out‐licensed drug candidates, the ability of our collaborators and of Array to meet objectives tied to milestones and royalties, our ability to attract and retain experienced scientists and management, and the risk factors set forth below under the caption “Risk Factors.” We are providing this information as of the date of this report. We undertake no duty to update any forward‐looking statements to reflect the occurrence of events or circumstances after the date of such statements or of unanticipated events that alter any assumptions underlying such statements.