Publication List 2014 - PuSH - Publikationsserver des Helmholtz

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2015-11-23
Publication List 2014
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joint first authors
° corresponding authors
HMGU authors are given in bold letters
Comprehensive Pneumology Center
Almouzni, G., Altucci, L., Amati, B., Ashley, N., Baulcombe, D., Beaujean, N., Bock, C., Bongcam-Rudloff, E.,
Bousquet, J., Braun, S., de Paillerets, B.B., Bussemakers, M., Clarke, L., Conesa, A., Estivill, X., Fazeli, A.,
Grgurevi, N.A., Gut, I., Heijmans, B.T., Hermouet, S., Houwing Duistermaat, J., Iacobucci, I., Ila, J.,
Kandimalla, R., Krauss-Etschmann, S., Lasko, P., Lehmann, S., Lindroth, A., Majdi, G., Marcotte, E.,
Martinelli, G., Martinet, N., Meyer, E., Miceli, C., Mills, K., Moreno-Villanueva, M., Morvan, G., Nickel, D.,
Niesler, B., Nowacki, M., Nowak, J., Ossowski, S., Pelizzola, M., Pochet, R., Poto Nik, U., Radwanska, M.,
Raes, J., Rattray, M., Robinson, M.D., Roelen, B., Sauer, S., Schinzer, D., Slagboom, E., Spector, T.,
Stunnenberg, H.G., Tiligada, E., Torres-Padilla, M.E., Tsonaka, R., van Soom, A., Vidakovi, M.,
Widschwendter, M.°: Relationship between genome and epigenome - challenges and requirements for future
research. BMC Genomics 15:487 (2014)
Ballweg, K., Mutze, K., Königshoff, M., Eickelberg, O., Meiners, S.°: Cigarette smoke extract affects
mitochondrial function in alveolar epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol. 307, 895-907 (2014)
Banon-Maneus, E.°, Rovira, J., Ramirez-Bajo, M.J., Moya-Rull, D., Hierro-Garcia, N., Takenaka, S.,
Diekmann, F., Eickelberg, O., Königshoff, M., Campistol, J.M.: Wnt pathway activation in long term
remnant rat model. Biomed Res. Int. 2014:324713 (2014)
Barapatre, N., Symvoulidis, P., Möller, W., Prade, F., Deliolanis, N.C., Hertel, S., Winter, G., Yildirim,
A.Ö., Stöger, T., Eickelberg, O., Ntziachristos, V., Schmid, O.°: Quantitative detection of drug dose and
spatial distribution in the lung revealed by Cryoslicing Imaging. J. Pharm. Biomed. Anal. 102, 129-136 (2015)
[published online 2014]
Berschneider, B., Ellwanger, D.C., Baarsma, H.A., Thiel, C.T., Shimbori, C., White, E.S., Kolb, M., Neth,
P., Königshoff, M.°: miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis. Int. J.
Biochem. Cell Biol. 53, 432-441 (2014)
Berti, C., Cetin, I., Agostoni, C., Desoye, G., Devlieger, R., Emmett, P.M., Ensenauer, R., Hauner, H.,
Herrera, E., Hoesli, I., Krauss-Etschmann, S., Olsen, S.F., Schaefer-Graf, U., Schiessl, B., Symonds, M.E.,
Koletzko, B.°: Pregnancy and infants' outcome: Nutritional and metabolic implications. Crit. Rev. Food Sci.
Nutr., DOI: 10.1080/10408398.2012.745477 (2014)
de Jong, T.M., Jochens, A., Jockel-Schneider, Y., Harks, I., Dommisch, H., Graetz, C., Flachsbart, F.,
Staufenbiel, I., Eberhard, J., Folwaczny, M., Noack, B., Meyle, J., Eickholz, P., Gieger, C., Grallert, H., Lieb,
W., Franke, A., Nebel, A., Schreiber, S., Doerfer, C., Jepsen, S., Bruckmann, C., van der Velden, U., Loos,
B.G., Schäfer, A.S.°, KORA Study Group (Holle, R., Illig, T., John, J., Meisinger, C., Peters, A.,
Wichmann, H.-E.): SLC23A1 polymorphism rs6596473 in the vitamin C transporter SVCT1 is associated
with aggressive periodontitis. J. Clin. Periodontol. 41, 531-540 (2014)
Geiser, M.°, Stöger, T., Casaulta, M., Chen, S., Semmler-Behnke, M., Bolle, I., Takenaka, S., Kreyling,
W.G., Schulz, S.: Biokinetics of nanoparticles and susceptibility to particulate exposure in a murine model of
cystic fibrosis. Part. Fibre Toxicol. 11:19 (2014)
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Gesierich, W.°, Samitas, K., Behr, J.: Determining collateral ventilation during bronchoscopy: Unanswered
questions. Thorax 69, 289-290 (2014)
Gregor, M.#, Osmanagic-Myers, S.#, Burgstaller, G., Wolfram, M., Fischer, I., Walko, G., Resch, G.P., Jörgl,
A., Herrmann, H., Wiche, G.°: Mechanosensing through focal adhesion-anchored intermediate filaments.
FASEB J. 28, 715-729 (2014)
Guarino, C., Legowska, M., Epinette, C., Kellenberger, C., Dallet-Choisy, S., Sienczyk, M., Gabant, G.,
Cadène, M., Zoidakis, J., Vlahou, A., Wysocka, M., Marchand-Adam, S., Jenne, D., Lesner, A., Gauthier, F.,
Korkmaz, B.°: New selective peptidyl di(chlorophenyl)-phosphonate esters to visualize and block neutrophil
proteinase 3 in human diseases. J. Biol. Chem. 289, 31777-31791 (2014)
Guyot, N., Wartelle, J., Malleret, L., Todorov, A.A., Devouassoux, G., Pacheco, Y., Jenne, D., Belaaouaj,
A.°: Unopposed cathepsin G, neutrophil elastase, and proteinase 3 cause severe lung damage and
emphysema. Am. J. Pathol. 184, 985-995 (2014)
Herber-Jonat, S., Vuckovic, A., Mittal, R., Hilgendorff, A., Jani, J.C., Flemmer, A.W.°: Intrapulmonary
instillation of perflurooctylbromide improves lung growth, alveolarization, and lung mechanics in a fetal rabbit
model of diaphragmatic hernia. Pediatr. Crit. Care Med. 15, e379-e388 (2014)
Herder, C.#°, Nuotio, M.L.#, Shah, S.#, Blankenberg, S., Brunner, E.J., Carstensen, M., Gieger, C., Grallert,
H., Jula, A., Kähönen, M., Kettunen, J., Kivimaki, M., Koenig, W., Kristiansson, K., Langenberg, C.,
Lehtimäki, T., Luotola, K., Marzi, C., Müller, C., Peters, A., Prokisch, H., Raitakari, O., Rathmann, W.,
Roden, M., Salmi, M., Schramm, K., Swerdlow, D.I., Tabak, A.G., Thorand, B., Wareham, N., Wild, P.S.,
Zeller, T., Hingorani, A.D., Witte, D.R., Kumari, M., Perola, M., Salomaa, V.: Genetic determinants of
circulating interleukin-1 receptor antagonist levels and their association with glycemic traits. Diabetes 63,
4343-4359 (2014)
Hilgendorff, A., Parai, K., Ertsey, R., Navarro, E.F., Jain, N., Carandang, F., Peterson, J., Mokres, L.M.,
Milla, C., Preuss, S., Alejandre Alcazar, M.A., Khan, S., Masumi, J., Ferreira-Tojais, N., Mujahid, S.,
Starcher, B.C., Rabinovitch, M., Bland, R.D.°: Lung matrix and vascular remodeling in mechanically
+/ventilated elastin haplo-insufficient (Eln ) newborn mice. Am. J. Physiol. Lung Cell Mol. Physiol. 308,
L464-L478 (2015) [published online 2014]
Hofer, T.P.°, Frankenberger, M., Heimbeck, I., Burggraf, D., Wjst, M., Wright, A.K.A., Kerscher, M.,
Nährig, S., Huber, R., Fischer, R., Ziegler-Heitbrock, L.: Decreased expression of HLA-DQ and HLA-DR on
cells of the monocytic lineage in cystic fibrosis. J. Mol. Med. 92, 1293-1304 (2014)
Huber, K.°, Aichler, M., Sun, N., Buck, A., Li, Z., Fernandez, I.E., Hauck, S.M., Zitzelsberger, H.,
Eickelberg, O., Janssen, K.P., Keller, U., Walch, A.K.°: A rapid ex vivo tissue model for optimising drug
detection and ionisation in MALDI imaging studies. Histochem. Cell Biol. 142, 361-371 (2014)
John-Schuster, G.#, Hager, K.#, Conlon, T.M., Irmler, M., Beckers, J., Eickelberg, O., Yildirim, A.Ö.°:
Cigarette smoke-induced iBALT mediates macrophage activation in a B cell-dependent manner in COPD.
Am. J. Physiol. Lung Cell Mol. Physiol. 307, L692-L706 (2014)
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Kaeuferle, T., Bartel, S., Dehmel, S., Krauss-Etschmann, S.°: MicroRNA methodology: Advances in
miRNA technologies. Methods Mol. Biol. 1169, 121-130 (2014)
Keeney, J.G., O'Bleness, M.S., Anderson, N., Davis, J.M., Arevalo, N., Busquet, N., Chick, W., Rozman, J.,
Hölter, S.M., Garrett, L., Horsch, M., German Mouse Clinic Consortium (Adler, T., Aguilar-Pimentel, J.A.,
Amarie, O.V., Eickelberg, O., Gailus-Durner, V., Graw, J., Hans, W., Horsch, M., Janik, D., Neff, F.,
Ollert, M., Puk, O., Rácz, I., Rathkolb, B., Stöger, T., Yildirim, A.Ö.), Beckers, J., Wurst, W.,
Klingenspor, M., Restrepo, D., Sikela, J.M.°, Hrabě de Angelis, M.°: Generation of mice lacking DUF1220
protein domains: Effects on fecundity and hyperactivity. Mamm. Genome 26, 33-42 (2015) [published online
2014]
Knoll, N., Jarick, I., Volckmar, A.L., Klingenspor, M., Illig, T., Grallert, H., Gieger, C., Wichmann, H.-E.,
Peters, A., Wiegand, S., Biebermann, H., Fischer-Posovszky, P., Wabitsch, M., Völzke, H., Nauck, M.,
Teumer, A., Rosskopf, D., Rimmbach, C., Schreiber, S., Jacobs, G., Lieb, W., Franke, A., Hebebrand, J.,
Hinney, A.°: Mitochondrial DNA variants in obesity. PLoS ONE 9:e94882 (2014)
Kraus, P., Sivakamasundari, V., Yu, H.B., Xing, X., Lim, S.L., Adler, T., Aguilar-Pimentel, J.A., Becker, L.,
Bohla, A., Garrett, L., Hans, W., Hölter, S.M., Janas, E., Moreth, K., Prehn, C., Puk, O., Rathkolb, B.,
Rozman, J., Adamski, J., Bekeredjian, R., Busch, D.H., Graw, J., Klingenspor, M., Klopstock, T., Neff,
F., Ollert, M., Stöger, T., Yildirim, A.Ö., Eickelberg, O., Wolf, E., Wurst, W., Fuchs, H., Gailus-Durner,
V., Hrabě de Angelis, M., Lufkin, T., Stanton, L.W.°: Pleiotropic functions for transcription factor Zscan10.
PLoS ONE 9:e104568 (2014)
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Krinninger, P. , Ensenauer, R. , Ehlers, K., Rauh, K., Stoll, J., Krauss-Etschmann, S., Hauner, H.,
Laumen, H.°: Peripheral monocytes of obese women display increased chemokine receptor expression and
migration capacity. J. Clin. Endocrinol. Metab. 99:jc20132611 (2014)
Lenz, A.-G., Stöger, T., Cei, D., Schmidmeir, M., Pfister, N., Burgstaller, G., Lentner, B., Eickelberg, O.,
Meiners, S., Schmid, O.°: Efficient bioactive delivery of aerosolized drugs to human pulmonary epithelial
cells cultured at air-liquid interface conditions. Am. J. Respir. Cell Mol. Biol. 51, 526-535 (2014)
Loison, F., Zhu, H., Karatepe, K., Kasorn, A., Liu, P., Ye, K., Zhou, J., Cao, S., Gong, H., Jenne, D.,
Remold-O'Donnell, E., Xu, Y., Luo, H.R.°: Proteinase 3-dependent caspase-3 cleavage modulates neutrophil
death and inflammation. J. Clin. Invest. 124, 4445-4458 (2014)
Meinel, F.G., Yaroshenko, A., Hellbach, K., Bech, M., Müller, M., Velroyen, A., Bamberg, F., Eickelberg, O.,
Nikolaou, K., Reiser, M.F., Pfeiffer, F., Yildirim, A.Ö.°: Improved diagnosis of pulmonary emphysema using
in vivo dark-field radiography. Invest. Radiol. 49, 653-658 (2014)
Meiners, S.°, Keller, I.E., Semren, N., Caniard, A.: Regulation of the proteasome: Evaluating the lung
proteasome as a new therapeutic target. Antioxid. Redox Signal. 21, 2364-2382 (2014)
Meis, T., Behr, J.°: Riociguat for the treatment of pulmonary hypertension. Expert Opin. Pharmacother. 15,
2419-2427 (2014)
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Noskovicova, N., Petrek, M., Eickelberg, O.°, Heinzelmann, K.°: PDGF signaling in the lung - from lung
development and disease to clinical studies. Am. J. Respir. Cell Mol. Biol. 52, 263-284 (2015) [published
online 2014]
Pain, M.°, Bermudez, O., Lacoste, P., Royer, P.J., Botturi, K., Tissot, A., Brouard, S., Eickelberg, O.,
Magnan, A.: Tissue remodelling in chronic bronchial diseases: From the epithelial to mesenchymal
phenotype. Eur. Respir. Rev. 23, 118-130 (2014)
Schamberger, A.C., Mise, N., Meiners, S., Eickelberg, O.°: Epigenetic mechanisms in COPD: Implications
for pathogenesis and drug discovery. Expert Opin. Drug Discov. 9, 609-628 (2014)
Schirmer, L., Srivastava, R., Kalluri, S.R., Boettinger, S., Herwerth, M., Carassiti, D., Srivastava, B., Gempt,
J., Schlegel, J., Kuhlmann, T., Korn, T., Reynolds, R., Hemmer, B.°: Differential loss of KIR4.1
immunoreactivity in multiple sclerosis lesions. Ann. Neurol. 75, 810-828 (2014)
van Rijt, S.H.°, Bein, T., Meiners, S.: Medical nanoparticles for next generation drug delivery to the lungs.
Eur. Respir. J. 44, 765-774 (2014)
Velroyen, A., Bech, M., Zanette, I., Schwarz, J., Rack, A., Tympner, C., Herrler, T., Staab-Weijnitz, C.A.,
Braunagel, M., Reiser, M., Bamberg, F., Pfeiffer, F., Notohamiprodjo, M.°: X-ray phase-contrast tomography
of renal ischemia-reperfusion damage. PLoS ONE 9:e109562 (2014)
Wang, S.R., Agarwala, V., Flannick, J., Chiang, C.W., Altshuler, D., GoT2D Consortium (Gieger, C.,
Grallert, H., Hrabě de Angelis, M., Huth, C., Kriebel, J., Meisinger, C., Meitinger, T., Müller-Nurasyid,
M., Ried, J.S., Peters, A., Rathmann, W., Strauch, K., Strom, T.M.°), Hirschhorn, J.N.°: Simulation of
finnish population history, guided by empirical genetic data, to assess power of rare-variant tests in Finland.
Am. J. Hum. Genet. 94, 710-720 (2014)
Yaroshenko, A., Meinel, F.G., Hellbach, K., Bech, M., Velroyen, A., Müller, M., Bamberg, F., Nikolaou, K.,
Reiser, M.F., Yildirim, A.Ö., Eickelberg, O., Pfeiffer, F.: Small-animal dark-field radiography for pulmonary
emphysema evaluation. Proc. SPIE 9033:90331M (2014)
Ziegler-Heitbrock, L.°: Monocyte subsets in man and other species. Cell. Immunol. 289, 135-139 (2014)
Ziegler-Heitbrock, L.°: Subpopulationen peripherer blutmonozyten: Grundlagen, diagnostik, krankheitsbilder
und therapeutische konsequenzen. Nieren- Hochdruck-Krankh. 42, 510-511 (2013)
Zimmermann, G.S.°, von Wulffen, W., Huppmann, P., Meis, T., Ihle, F., Geiseler, J., Leuchte, H.H.,
Tufman, A., Behr, J., Neurohr, C.: Haemodynamic changes in pulmonary hypertension in patients with
interstitial lung disease treated with PDE-5 inhibitors. Respirology 19, 700-706 (2014)
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Cooperation Group Comprehensive Molecular Analytics
Breuer, D., Friedrich, C., Moehlmann, C., Dragan, G.-C.: Entwicklung eines miniaturisierten
Probenahmesystems zur gleichzeitigen Erfassung von Dampf-Tröpfchen-Gemischen bei schwerflüchtigen
Verbindungen. Gefahrstoffe Reinhalt. Luft 74, 129-134 (2014)
Crilley, L.R., Qadir, R.M., Ayoko, G.A.°, Schnelle-Kreis, J., Abbaszade, G., Orasche, J., Zimmermann,
R., Morawska, L.: Identification of the sources of primary organic aerosols at urban schools: A molecular
marker approach. Environ. Pollut. 191, 158-165 (2014)
Diab, J., Hertz-Schünemann, R., Streibel, T.°, Zimmermann, R.: Online measurement of volatile organic
compounds released during roasting of cocoa beans. Food Res. Int. 63, 344-352 (2014)
Dragan, G.-C., Breuer, D., Blaskowitz, M., Karg, E.W., Schnelle-Kreis, J.°, Arteaga-Salas, J.M.,
Nordsieck, H., Zimmermann, R.: An evaluation of the "GGP" personal samplers under semi-volatile
aerosols: Sampling losses and their implication on occupational risk assessment. Environ. Sci. Process
Impacts 17, 270-277 (2015) [published online 2014]
Dragan, G.-C., Karg, E.W., Nordsieck, H., Schnelle-Kreis, J.°, Breuer, D., Arteaga-Salas, J.M., Ferron,
G.A., Zimmermann, R.: Short-term evaporation of semi-volatile N-alkane aerosol particles: Experimental
and computational approach. Environ. Eng. Manag. J. 13, 1775-1785 (2014)
Fischer, M., Wohlfahrt, S., Varga, J., Saraji-Bozorgzad, M., Matuschek, G.°, Denner, T., Zimmermann,
R.: Evolved gas analysis by single photon ionization-mass spectrometry. J. Therm. Anal. Calorim. 116,
1461-1469 (2014)
Hertz-Schünemann, R., Dorfner, R., Yeretzian, C., Streibel, T., Zimmermann, R.°: On-line process
monitoring of coffee roasting by resonant laser ionisation time-of-flight mass spectrometry: Bridging the gap
from industrial batch roasting to flavour formation inside an individual coffee bean. J. Mass Spectrom. 48,
1253-1265 (2013)
Hölzer, J., Fischer, M., Gröger, T.M., Streibel, T., Saraji-Bozorgzad, M., Wohlfahrt, S., Matuschek, G.,
Zimmermann, R.°: Hyphenation of Thermogravimetry and Soft single Photon Ionization-Ion Trap Mass
Spectrometry (TG-SPI-ITMS) for evolved gas analysis. J. Therm. Anal. Calorim. 116, 1471-1479 (2014)
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Huang, R.J. , Zhang, Y., Bozzetti, C., Ho, K.F., Cao, J.J.°, Han, Y., Daellenbach, K.R., Slowik, J.G., Platt,
S.M., Canonaco, F., Zotter, P., Wolf, R., Pieber, S.M., Bruns, E.A., Crippa, M., Ciarelli, G., Piazzalunga, A.,
Schwikowski, M., Abbaszade, G., Schnelle-Kreis, J., Zimmermann, R., An, Z., Szidat, S., Baltensperger,
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U., Haddad, I.E. , Prevot, A.S.H.°: High secondary aerosol contribution to particulate pollution during haze
events in China. Nature 514, 218-222 (2014)
Jakobi, G.°, Kirchner, M., Henkelmann, B., Körner, W., Offenthaler, I., Moche, W., Weiß, P.S., Schaub, M.,
Schramm, K.-W.: Atmospheric bulk deposition measurements of organochlorine pesticides at three alpine
summits. Atmos. Environ. 101, 158-165 (2015)
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Jennerwein, M., Eschner, M., Gröger, T.M., Wilharm, T., Zimmermann, R.°: Complete group-type
quantification of petroleum middle distillates based on comprehensive two-dimensional Gas Chromatography
Time-of-Flight Mass Spectrometry (GCxGC-TOFMS) and visual basic scripting. Energy Fuels 28, 5670-5681
(2014)
Leskinen, J.°, Ihalainen, M., Torvela, T., Kortelainen, M., Lamberg, H., Tiitta, P., Jakobi, G., Grigonyte, J.,
Joutsensaari, J., Sippula, O., Tissari, J., Virtanen, A., Zimmermann, R., Jokiniemi, J.: Effective density and
morphology of particles emitted from small-scale combustion of various wood fuels. Environ. Sci. Technol.
48, 13298-13306 (2014)
Luebbe, C., Dumrath, A., Neumann, H., Schäffer, M., Zimmermann, R., Beller, M., Kadyrov, R.°: How
important are impurities in catalysis? An example from ring-closing metathesis. ChemCatChem 6, 684-688
(2014)
Ly-Verdú, S., Gröger, T.M.°, Arteaga-Salas, J.M., Brandmaier, S., Kahle, M., Neschen, S., Hrabě de
Angelis, M., Zimmermann, R.: Combining metabolomic non-targeted GC×GC-ToF-MS analysis and
chemometric ASCA-based study of variances to assess dietary influence on type 2 diabetes development in
a mouse model. Anal. Bioanal. Chem. 407, 343-354 (2015) [published online 2014]
Platt, S.M., Haddad, I.E., Pieber, S.M., Huang, R.J., Zardini, A.A., Clairotte, M., Suarez-Bertoa, R., Barmet,
P., Pfaffenberger, L., Wolf, R., Slowik, J.G., Fuller, S.J., Kalberer, M., Chirico, R., Dommen, J., Astorga, C.,
Zimmermann, R., Marchand, N., Hellebust, S., Temime-Roussel, B., Baltensperger, U., Prévôt, A.S.°:
Two-stroke scooters are a dominant source of air pollution in many cities. Nat. Commun. 5:3749 (2014)
Qadir, R.M.°, Schnelle-Kreis, J., Abbaszade, G., Arteaga-Salas, J.M., Diemer, J., Zimmermann, R.:
Spatial and temporal variability of source contributions to ambient PM10 during winter in Augsburg, Germany
using organic and inorganic tracers. Chemosphere 113, 263-273 (2014)
Reda, A.°, Schnelle-Kreis, J.°, Orasche, J., Abbaszade, G., Lintelmann, J., Arteaga-Salas, J.M.,
Stengel, B., Rabe, R., Harndorf, H., Sippula, O., Streibel, T., Zimmermann, R.: Gas phase carbonyl
compounds in ship emissions: Differences between diesel fuel and heavy fuel oil operation. Atmos. Environ.
94, 467-478 (2014)
Sánchez, J., Zimmermann, R., Yeretzian, C.°: Insight into the time-resolved extraction of aroma compounds
during espresso coffee preparation: Online monitoring by PTR-ToF-MS. Anal. Chem. 86, 11696-11704
(2014)
Schaumann, F., Frömke, C., Dijkstra, D., Alessandrini, F., Windt, H., Karg, E.W., Müller, M., Winkler, C.,
Braun, A., Koch, A., Hohlfeld, J., Behrendt, H., Schmid, O., Koch, W., Schulz, S., Krug, N.°: Effects of
ultrafine particles on the allergic inflammation in the lung of asthmatics: Results of a double-blinded
randomized cross-over clinical pilot study. Part. Fibre Toxicol. 11:39 (2014)
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Sippula, O.°, Stengel, B., Sklorz, M., Streibel, T., Rabe, R., Orasche, J., Lintelmann, J., Michalke, B.,
Abbaszade, G., Radischat, C., Gröger, T.M., Schnelle-Kreis, J., Harndorf, H., Zimmermann, R.: Particle
emissions from a marine engine: Chemical composition and aromatic emission profiles under various
operating conditions. Environ. Sci. Technol. 48, 11721-11729 (2014)
Streibel, T.°, Mühlberger, F., Geißler, R., Saraji-Bozorgzad, M.R., Adam, T.W., Zimmermann, R.:
Influence of sulphur addition on emissions of polycyclic aromatic hydrocarbons during biomass combustion.
Proc. Combust. Inst. 35, 1771-1777 (2015) [published online 2014]
Streibel, T.°, Zimmermann, R.°: Resonance-Enhanced Multiphoton Ionization Mass Spectrometry
(REMPI-MS): Applications for process analysis. Annu. Rev. Anal. Chem. 7, 361-381 (2014)
Weggler, B.A., Gröger, T.M.°, Zimmermann, R.: Advanced scripting for the automated profiling of
two-dimensional gas chromatography-time-of-flight mass spectrometry data from combustion aerosol. J.
Chromatogr. A 1364, 241-248 (2014)
Westmeyer, G.G., Emer, Y., Lintelmann, J., Jasanoff, A.°: MRI-based detection of alkaline phosphatase
gene reporter activity using a porphyrin solubility switch. Chem. Biol. 21, 422-429 (2014)
Winkler-Heil, R., Ferron, G.A., Hofmann, W.°: Calculation of hygroscopic particle deposition in the human
lung. Inhal. Toxicol. 26, 193-206 (2014)
Zhang, Y.°, Liu, J., Salazar, G.A., Li, J., Zotter, P., Zhang, G., Shen, R., Schäfer, K., Schnelle-Kreis, J.,
Prevot, A.S.H., Szidat, S.°: Micro-scale (µg) radiocarbon analysis of water-soluble organic carbon in aerosol
samples. Atmos. Environ. 97, 1-5 (2014)
Zotter, P., El-Haddad, I., Zhang, Y., Hayes, P.L., Zhang, X., Lin, Y., Wacker, L., Schnelle-Kreis, J.,
Abbaszade, G., Zimmermann, R., Surratt, J.D., Weber, R., Jimenez, J.L., Szidat, S., Baltensperger, U.,
Prevot, A.S.H.°: Diurnal cycle of fossil and nonfossil carbon using radiocarbon analyses during CalNex. J.
Geophys. Res. D-Atmos. 119, 6818-6835 (2014)
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German Center for Diabetes Reseach
Achenbach, P., Winkler, C., Haupt, F., Beyerlein, A., Ziegler, A.-G.°: Prädisposition, frühe Stadien und
Phänotypen des Typ-1-Diabetes. Dtsch. Med. Wochenschr. 139, 1100-1104 (2014)
Al-Massadi, O., Lear, P.V., Müller, T.D., Lopez, M.A., Dieguez, C., Tschöp, M.H., Nogueiras, R.°: Review of
novel aspects of the regulation of ghrelin secretion. Curr. Drug Metab. 15, 398-413 (2014)
Altmaier, E.°, Fobo, G., Heier, M., Thorand, B., Meisinger, C., Römisch-Margl, W., Waldenberger, M.,
Gieger, C., Illig, T., Adamski, J., Suhre, K., Kastenmüller, G.: Metabolomics approach reveals effects of
antihypertensives and lipid-lowering drugs on the human metabolism. Eur. J. Epidemiol. 29, 325-336 (2014)
Aoqui, C., Chmielewski, S., Scherer, E., Eissler, R., Sollinger, D., Heid, I., Braren, R., Schmaderer, C.,
Megens, R.T., Weber, C., Heemann, U., Tschöp, M.H., Baumann, M.°: Microvascular dysfunction in the
course of metabolic syndrome induced by high-fat diet. Cardiovasc. Diabetol. 13:31 (2014)
+
+
-
Arndt, B.°, Witkowski, L., Ellwart, J.W., Seissler, J.: CD8 CD122 PD-1 effector cells promote the
development of diabetes in NOD mice. J. Leukoc. Biol. 97, 111-120 (2015) [published online 2014]
Bender, C.°, Schlosser, M., Christen, U., Ziegler, A.-G., Achenbach, P.°: GAD autoantibody affinity in
schoolchildren from the general population. Diabetologia 57, 1911-1918 (2014)
Böhm, A.°, Halama, A., Meile, T., Zdichavsky, M., Lehmann, R., Weigert, C., Fritsche, A., Stefan, N.,
Königsrainer, A., Häring, H.-U., Hrabě de Angelis, M., Adamski, J., Staiger, H.: Metabolic signatures of
cultured human adipocytes from metabolically healthy versus unhealthy obese individuals. PLoS ONE
9:e93148 (2014)
Bongaerts, B.W.°, Ziegler, D., Shaw, J.E., Heier, M., Kowall, B., Herder, C., Roden, M., Peters, A.,
Meisinger, C., Rathmann, W.: A clinical screening score for diabetic polyneuropathy: KORA F4 and AusDiab
studies. J. Diab. Complic. 29, 44-49 (2015) [published online 2014]
Breier, M.°, Wahl, S., Prehn, S., Fugmann, M., Ferrari, U., Weise, M., Banning, F., Seissler, J., Grallert,
H., Adamski, J., Lechner, A.: Targeted metabolomics identifies reliable and stable metabolites in human
serum and plasma samples. PLoS ONE 9:e89728 (2014)
Broer, L.#°, Raschenberger, J.#, Deelen, J.#, Mangino, M., Codd, V., Pietiläinen, K.H., Albrecht, E., Amin, N.,
Beekman, M., De Craen, A.J.M., Gieger, C., Haun, M., Henneman, P., Herder, C., Hovatta, I., Laser, A.,
Kedenko, L., Koenig, W., Kollerits, B., Moilanen, E., Oostra, B.A., Paulweber, B., Quaye, L., Rissanen, A.,
Roden, M., Surakka, I., Valdes, A.M., Vuolteenaho, K., Thorand, B., van Dijk, K.W., Kaprio, J., Spector,
T.D., Slagboom, P.E., Samani, N.J., Kronenberg, F., van Duijn, C.M.°, Ladwig, K.-H.: Association of
adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448
participants. Eur. J. Epidemiol. 29, 629-638 (2014)
Busse, S., Lutter, D., Heldmaier, G., Jastroch, M., Meyer, C.W.°: Torpor at high ambient temperature in a
neotropical didelphid, the grey short-tailed opossum (Monodelphis domestica). Naturwissenschaften 101,
1003-1006 (2014)
page 8 of 247
2015-11-23
#
joint first authors
Cansell, C., Castel, J., Denis, R.G., Rouch, C., Delbes, A.S., Martinez, S., Mestivier, D., Finan, B.,
Maldonado-Aviles, J.G., Rijnsburger, M., Tschöp, M.H., Dileone, R.J., Eckel, R.H., la Fleur, S.E., Magnan,
C., Hnasko, T.S., Luquet, S.°: Dietary triglycerides act on mesolimbic structures to regulate the rewarding
and motivational aspects of feeding. Mol. Psychiatry 19, 1095-1105 (2014)
Claussnitzer, M.°, Dankel, S.N., Klocke, B., Grallert, H., Glunk, V., Berulava, T., Lee, H.K., Oskolkov, N.,
Fadista, J., Ehlers, K., Wahl, S., Hoffmann, C., Qian, K., Rönn, T., Riess, H., Müller-Nurasyid, M.,
Bretschneider, N., Schroeder, T., Skurk, T., Horsthemke, B., DIAGRAM Consortium (Gieger, C., Huth, C.,
Klopp, N., Meitinger, T., Petersen, A.-K., Thorand, B., Wichmann, H.-E.), Spieler, D., Klingenspor, M.,
Seifert, M., Kern, M.J., Mehjert, N., Dahlman, I., Hansson, O., Hauck, S.M., Blüher, M., Arner, P., Groop, L.,
Illig, T., Suhre, K., Hsu, Y.H., Mellgren, G., Hauner, H., Laumen, H.°: Leveraging cross-species
transcription factor binding site patterns: From diabetes risk loci to disease mechanisms. Cell 156, 343-358
(2014)
DIAGRAM Consortium (Gieger, C., Grallert, H., Illig, T., Klopp, N., Müller-Nurasyid, M., Peters, A.),
AGEN-T2D Consortium, SAT2D Consortium, MAT2D Consortium, T2D-GENES Consortium, Boehnke, M.°,
Parra, E.J.°, Chambers, J.C.°, Tai, E.S.°, McCarthy, M.I°, Morris, A.P.°: Genome-wide trans-ancestry
meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat. Genet. 46,
234-244 (2014)
Dick, K.J., Nelson, C.P., Tsaprouni, L., Sandling, J.K., Aïssi, D., Wahl, S., Meduri, E., Morange, P.E.,
Gagnon, F., Grallert, H., Waldenberger, M., Peters, A., Erdmann, J., Hengstenberg, C., Cambien, F.,
Goodall, A.H., Ouwehand, W.H., Schunkert, H., Thompson, J.R., Spector, T.D., Gieger, C., Tregouet, D.A.,
Deloukas, P., Samani, N.J.°: DNA methylation and body-mass index: A genome-wide analysis. Lancet 383,
1990-1998 (2014)
Dullaart, R.P., Al-Daghri, N.M., Ashina, M., Bouzas-Mosquera, A., Brunetti, N.D., Buechler, C., Chen, H.S.,
Corrales, J.J., D'Archivio, M., Cas, A.D., Pino, G.G., Gómez-Abril, S.A., Győri, D., Haslacher, H., Herder, C.,
Kerstens, M.N., Koutsilieris, M., Lombardi, C., Lupattelli, G., Mócsai, A., Msaouel, P., Orfao, A., Ormazabal,
P., Pacher, R., Perkmann, T., Peteiro, J., Plischke, M., Reynaert, N.L., Ricci, M.A., Robles, N.R., Rocha, M.,
Rutten, E.P., Sabico, S., Santamaria, F., Santoro, F., Schmid, A., Schmidt, M., Schytz, H.W., Shyu, K.G.,
Tada, H., Thorand, B., Valerio, G., Vesely, D.L., Wu, T.E., Yamagishi, M., Yeh, Y.T.: Research update for
articles published in EJCI in 2012. Eur. J. Clin. Invest. 44, 1010-1023 (2014)
#
#
Eichner, J. , Rosenbaum, L. °, Wrzodek, C., Häring, H.-U., Zell, A., Lehmann, R.°: Integrated enrichment
analysis and pathway-centered visualization of metabolomics, proteomics, transcriptomics, and genomics
data by using the InCroMAP software. J. Chromatogr. B 966, 77-82 (2014)
page 9 of 247
2015-11-23
#
joint first authors
Ellis, J., Lange, E.M., Li, J., Dupuis, J., Baumert, J.J., Walston, J.D., Keating, B.J., Durda, P., Fox, E.R.,
Palmer, C.D., Meng, Y.A., Young, T., Farlow, D.N., Schnabel, R.B., Marzi, C., Larkin, E., Martin, L.W., Bis,
J.C., Auer, P., Ramachandran, V.S., Gabriel, S.B., Willis, M.S., Pankow, J.S., Papanicolaou, G.J., Rotter,
J.I., Ballantyne, C.M., Gross, M.D., Lettre, G., Wilson, J.G., Peters, U., Koenig, W., Tracy, R.P., Redline, S.,
Reiner, A.P., Benjamin, E.J., Lange, L.A.°: Large multiethnic candidate gene study for C-reactive protein
levels: Identification of a novel association at CD36 in African Americans. Hum. Genet. 133, 985-995 (2014)
Ellwanger, D.C.°, Leonhardt, J., Mewes, H.-W.: Large-scale modeling of condition-specific gene regulatory
networks by information integration and inference. Nucleic Acids Res. 42:e166 (2014)
#
#
Endesfelder, D. , zu Castell, W. , Ardissone, A., Davis-Richardson, A.G., Achenbach, P., Hagen, M.,
Pflueger, M., Gano, K.A., Fagen, J.R., Drew, J.C., Brown, C.T., Kolaczkowski, B., Atkinson, M.J., Schatz,
D., Bonifacio, E., Triplett, E.W., Ziegler, A.-G.°: Compromised gut microbiota networks in children with
anti-islet cell autoimmunity. Diabetes 63, 2006-2014 (2014)
Ferreira, R.C., Guo, H., Coulson, R.M., Smyth, D.J., Pekalski, M.L., Burren, O.S., Cutler, A.J., Doecke, J.D.,
Flint, S., McKinney, E.F., Lyons, P.A., Smith, K.G., Achenbach, P., Beyerlein, A., Dunger, D.B., Wicker,
L.S., Todd, J.A.°, Bonifacio, E.°, Wallace, C.°, Ziegler, A.-G.°: A type I interferon transcriptional signature
precedes autoimmunity in children genetically at risk of type 1 diabetes. Diabetes 63, 2538-2550 (2014)
Finan, B.°, Yang, B., Ottaway, N., Smiley, D.L., Ma, T., Clemmensen, C., Chabenne, J., Zhang, L.,
Habegger, K.M., Fischer, K., Campbell, J.E., Sandoval, D.A., Seeley, R.J., Bleicher, K., Uhles, S., Riboulet,
W., Funk, J., Hertel, C., Belli, S., Sebokova, E., Conde-Knape, K., Konkar, A., Drucker, D.J., Gelfanov, V.,
Pfluger, P.T., Müller, T.D., Perez-Tilve, D., DiMarchi, R.D.°, Tschöp, M.H.°: A rationally designed
monomeric peptide triagonist corrects obesity and diabetes in rodents. Nat. Med. 21, 27-36 (2015) [published
online 2014]
Flaquer, A.°, Baumbach, C., Kriebel, J., Meitinger, T., Peters, A., Waldenberger, M., Grallert, H.,
Strauch, K.: Mitochondrial genetic variants identified to be associated with BMI in adults. PLoS ONE
9:e105116 (2014)
Floegel, A.°, Wientzek, A., Bachlechner, U., Jacobs, S., Drogan, D., Prehn, C., Adamski, J., Krumsiek, J.,
Schulze, M.B., Pischon, T., Boeing, H.: Linking diet, physical activity, cardiorespiratory fitness and obesity to
serum metabolite networks: Findings from a population-based study. Int. J. Obes. 38, 1388-1396 (2014)
Frank, S.°, Wilms, B., Veit, R., Ernst, B., Thurnheer, M., Kullmann, S., Fritsche, A., Birbaumer, N., Preissl,
H., Schultes, B.: Altered brain activity in severely obese women may recover after Roux-en Y gastric bypass
surgery. Int. J. Obes. 38, 341-348 (2014)
#
#
#
Friedrich, N. , Wolthers, O.D. , Arafat, A.M. , Emeny, R.T., Spranger, J., Roswall, J., Kratzsch, J., Grabe,
H.J., Hübener, C., Pfeiffer, A.F.H., Döring, A., Bielohuby, M., Dahlgren, J., Frystyk, J.J., Wallaschofski, H.,
Bidlingmaier, M.°: Age- and sex-specific reference intervals across life span for Insulin-like Growth Factor
Binding Protein 3 (IGFBP-3) and the IGF-i to IGFBP-3 ratio measured by new automated
chemiluminescence assays. J. Clin. Endocrinol. Metab. 99, 1675-1686 (2014)
page 10 of 247
2015-11-23
#
joint first authors
#
#
Fuchs, Y.F. , Adler, K. , Lindner, A., Karasinsky, A., Wilhelm, C., Weigelt, M., Balke, H., Förtsch, K.,
Mortler-Hildebrandt, L.F., Harlan, D.M., Pechhold, K., Ziegler, A.-G., Bonifacio, E.°: Igrp and insulin
+
vaccination induce CD8 T cell mediated autoimmune diabetes in the RIP-CD80GP mouse. Clin. Exp.
Immunol. 176, 199-206 (2014)
Gegg, M., Böttcher, A., Burtscher, I., Hasenöder, S., van Campenhout, C.A., Aichler, M., Walch, A.K.,
Grant, S.G., Lickert, H.°: Flattop regulates basal body docking and positioning in mono- and multiciliated
cells. eLife 3:e03842 (2014)
Gerdes, J.M., Christou-Safina, S., Xiong, Y., Moede, T., Moruzzi, N., Karlsson-Edlund, P., Leibiger, B.,
Leibiger, I., Ostenson, C.G., Beales, P., Berggren, P.O.°: Ciliary dysfunction impairs beta-cell insulin
secretion and promotes development of type 2 diabetes in rodents. Nat. Commun. 5:5308 (2014)
Goldman, O.#, Han, S.#, Hamou, W., Jodon de Villeroche, V., Uzan, G., Lickert, H., Gouon-Evans, V.°:
Endoderm generates endothelial cells during liver development. Stem Cell Rep. 3, 556-565 (2014)
Gutierrez-Aguilar, R., Kim, D., Casimir, M., Dai, X., Pfluger, P.T., Park, J., Haller, A., Donelan, E., D'Alessio,
D., Woods, S.C., MacDonald, P.E., Seeley, R.J.°: The role of the transcription factor ETV5 in insulin
exocytosis. Diabetologia 57, 383-391 (2014)
Heni, M., Wagner, R.°, Kullmann, S., Veit, R., Mat-Husin, H., Linder, K., Benkendorff, C., Peter, A., Stefan,
N., Häring, H.-U., Preissl, H., Fritsche, A.: Central insulin administration improves whole-body insulin
sensitivity via hypothalamus and parasympathetic outputs in men. Diabetes 63, 4083-4088 (2014)
#
#
#
Heni, M. , Schöpfer, P. , Peter, A. , Sartorius, T., Fritsche, A.°, Synofzik, M., Häring, H.-U., Maetzler, W.,
Hennige, A.M.: Evidence for altered transport of insulin across the blood-brain barrier in insulin-resistant
humans. Acta Diabetol. 51, 679-681 (2013)
Heni, M., Kullmann, S.°, Veit, R., Ketterer, C., Frank, S., Machicao, F., Staiger, H., Häring, H.-U., Preissl,
H., Fritsche, A.: Variation in the obesity risk gene FTO determines the postprandial cerebral processing of
food stimuli in the prefrontal cortex. Mol. Metab. 3, 109-113 (2014)
Herder, C.°, Bongaerts, B.W., Rathmann, W., Heier, M., Kowall, B., Koenig, W., Thorand, B., Roden, M.,
Meisinger, C.°, Ziegler, D.°: Differential association between biomarkers of subclinical inflammation and
painful polyneuropathy: Results from the KORA F4 study. Diabetes Care 38, 91-96 (2015) [published online
2014]
Herder, C.#°, Nuotio, M.L.#, Shah, S.#, Blankenberg, S., Brunner, E.J., Carstensen, M., Gieger, C., Grallert,
4343-4359 (2014)
page 11 of 247
2015-11-23
#
joint first authors
#
#
Hernandez, E.D. , Lee, S.J. , Kim, J.Y., Duran, A., Linares, J.F., Yajima, T., Müller, T.D., Tschöp, M.H.,
Smith, S.R., Diaz-Meco, M.T., Moscat, J.°: A macrophage NBR1-MEKK3 complex triggers JNK-mediated
adipose tissue inflammation in obesity. Cell Metab. 20, 499-511 (2014)
Hoene, M.#, Li, J.#, Häring, H.-U., Weigert, C., Xu, G., Lehmann, R.°: The lipid profile of brown adipose
tissue is sex-specific in mice. Biochim. Biophys. Acta-Mol. Cell Biol. Lipids 1841, 1563-1570 (2014)
Horsch, M., Beckers, J., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis, M., Rathkolb, B., Wolf, E.,
Aigner, B., Kemter, E.°: Uromodulin retention in thick ascending limb of Henle's loop affects SCD1 in
neighboring proximal tubule: Renal transcriptome studies in mouse models of uromodulin-associated kidney
disease. PLoS ONE 9:e113125 (2014)
Hunger, M.°, Holle, R., Meisinger, C., Rathmann, W., Peters, A., Schunk, M.: Longitudinal changes in
health-related quality of life in normal glucose tolerance, prediabetes and type 2 diabetes: Results from the
KORA S4/F4 cohort study. Qual. Life Res. 23, 2515-2520 (2014)
Huth, C., Thorand, B., Baumert, J.J., Kruse, J., Emeny, R.T., Schneider, A.E., Meisinger, C., Ladwig,
K.-H.°: Job strain as a risk factor for the onset of type 2 diabetes mellitus: Findings from the MONICA/KORA
Augsburg cohort study. Psychosom. Med. 76, 562-568 (2014)
International League Against Epilepsy Consortium on Complex Epilepsies (Gieger, C., Grallert, H.,
Heinrich, J., Holle, R., Leidl, R., Meisinger, C., Peters, A., Strauch, K.): Genetic determinants of common
epilepsies: A meta-analysis of genome-wide association studies. Lancet Neurol. 13, 893-903 (2014)
Islam, S.°, Lechner, A., Ferrari, U., Froeschl, G., Alam, D., Holle, R., Seissler, J., Niessen, L.W.: Mobile
phone intervention for increasing adherence to treatment for type 2 diabetes in an urban area of Bangladesh:
Protocol for a randomized controlled trial. BMC Health Serv. Res. 14:586 (2014)
Jacobs, S., Schiller, K., Jansen, E., Fritsche, A., Weikert, C., di Giuseppe, R., Boeing, H., Schulze, M.B.,
Kröger, J.°: Association between erythrocyte membrane fatty acids and biomarkers of dyslipidemia in the
EPIC-Potsdam study. Eur. J. Clin. Nutr. 68, 517-525 (2014)
Jacobs, S., Kröger, J., Floegel, A., Boeing, H., Drogan, D., Pischon, T., Fritsche, A., Prehn, C., Adamski,
J., Isermann, B., Weikert, C., Schulze, M.B.°: Evaluation of various biomarkers as potential mediators of the
association between coffee consumption and incident type 2 diabetes in the EPIC-Potsdam study. Am. J.
Clin. Nutr. 100, 891-900 (2014)
Jastroch, M.°, Keipert, S., Perocchi, F.: From explosives to physiological combustion: Next generation
chemical uncouplers. Mol. Metab. 3, 86-87 (2014)
Jastroch, M., Morin, S., Tschöp, M.H., Yi, C.-X.°: The hypothalamic neural-glial network and the metabolic
syndrome. Best Pract. Res. Clin. Endocrinol. Metab. 28, 661-671 (2014)
page 12 of 247
2015-11-23
#
joint first authors
Kahle, M., Schäfer, A., Seelig, A., Schultheiß, J., Wu, M., Aichler, M.°, Leonhardt, J., Rathkolb, B.,
Rozman, J., Sarioglu, H., Hauck, S.M., Ueffing, M., Wolf, E., Kastenmüller, G., Adamski, J., Walch,
A.K., Hrabě de Angelis, M., Neschen, S.: High fat diet-induced modifications in membrane lipid and
mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice.
Mol. Metab. 4, 39-50 (2015) [published online 2014]
Karp, N.A.°, Speak, A.O., White, J.K., Adams, D.J., Hrabě de Angelis, M., Herault, Y., Mott, R.F.: Impact of
temporal variation on design and analysis of mouse knockout phenotyping studies. PLoS ONE 9:e111239
(2014)
2014]
Keipert, S.°, Ost, M., Johann, K., Imber, F., Jastroch, M., van Schothorst, E.M., Keijer, J., Klaus, S.:
Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a
myokine. Am. J. Physiol. Endocrinol. Metab. 306, E469-E482 (2014)
Keller, J., Catala-Lehnen, P., Huebner, A.K., Jeschke, A., Heckt, T., Lueth, A., Krause, M., Koehne, T.,
Albers, J., Schulze, J., Schilling, S., Haberland, M., Denninger, H., Neven, M., Hermans-Borgmeyer, I.,
Streichert, T., Breer, S., Barvencik, F., Levkau, B., Rathkolb, B., Wolf, E., Calzada-Wack, J., Neff, F.,
Gailus-Durner, V., Fuchs, H., Hrabě de Angelis, M., Klutmann, S., Tsourdi, E., Hofbauer, L.C., Kleuser, B.,
Chun, J., Schinke, T., Amling, M.°: Calcitonin controls bone formation by inhibiting the release of sphingosine
1-phosphate from osteoclasts. Nat. Commun. 5:5215 (2014)
Kemter, E.#°, Sklenak, S.#, Rathkolb, B., Hrabě de Angelis, M., Wolf, E., Aigner, B., Wanke, R.: No
amelioration of uromodulin maturation and trafficking defect by sodium-4-phenylbutyrate in vivo: Studies in
mouse models of uromodulin-associated kidney disease. J. Biol. Chem. 289, 10715-10726 (2014)
Kemter, E., Rathkolb, B., Becker, L., Bolle, I., Busch, D.H., Dalke, C., Elvert, R., Favor, J., Graw, J.,
Hans, W., Ivandic, B., Kaladydjiev, S., Klopstock, T., Rácz, I., Rozman, J., Schrewe, A., Schulz, S.,
Zimmer, A., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis, M., Wolf, E., Aigner, B.°: Standardized,
I299F
systemic phenotypic analysis of Slc12a1
mutant mice. J. Biomed. Sci. 21:68 (2014)
Kenar, E., Franken, H., Forcisi, S., Wörmann, K., Häring, H.-U., Lehmann, R., Schmitt-Kopplin, P., Zell,
A., Kohlbacher, O.°: Automated label-free quantification of metabolites from liquid chromatography-mass
spectrometry data. Mol. Cell. Proteomics 13, 348-359 (2014)
page 13 of 247
2015-11-23
#
joint first authors
Ketterer, C., Heni, M., Stingl, K.T., Tschritter, O., Linder, K., Wagner, R., Machicao, F., Häring, H.-U.,
Preissl, H., Staiger, H., Fritsche, A.°: Polymorphism rs3123554 in CNR2 reveals gender-specific effects on
body weight and affects loss of body weight and cerebral insulin action. Obesity 22, 925-931 (2014)
Kim, J.G., Suyama, S., Koch, M., Jin, S., Argente-Arizon, P., Argente, J., Liu, Z.W., Zimmer, M.R., Jeong,
J.K., Szigeti-Buck, K., Gao, Y., García-Cáceres, C., Yi, C.-X., Salmaso, N., Vaccarino, F.M., Chowen, J.,
Diano, S., Dietrich, M.O., Tschöp, M.H., Horvath, T.L.°: Leptin signaling in astrocytes regulates
hypothalamic neuronal circuits and feeding. Nat. Neurosci. 17, 908-910 (2014)
#
#
Kistler, M. °, Szymczak, W. , Fedrigo, M., Fiamoncini, J., Höllriegl, V., Hoeschen, C., Klingenspor, M.,
Hrabě de Angelis, M., Rozman, J.°: Effects of diet-matrix on volatile organic compounds in breath in
diet-induced obese mice. J. Breath Res. 8:016004 (2014)
Koch, W.°, Forcisi, S., Lehmann, R., Schmitt-Kopplin, P.°: Sensitivity improvement in hydrophilic
interaction chromatography negative mode electrospray ionization mass spectrometry using
2-(2-methoxyethoxy)ethanol as a post-column modifier for non-targeted metabolomics. J. Chromatogr. A
1361, 209-216 (2014)
Koivula, R.W., Heggie, A., Barnett, A., Cederberg, H., Hansen, T.H., Koopman, A.D., Ridderstråle, M.,
Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M.W., Perry, M.H., Rauh, S., Siloaho, M.,
Teare, H.J., Thorand, B., Bell, J., Brunak, S., Frost, G., Jablonka, B., Mari, A., McDonald, T.J., Dekker, J.M.,
Hansen, T., Hattersley, A., Laakso, M., Pedersen, O., Koivisto, V., Ruetten, H., Walker, M., Pearson, E.,
Franks, P.W.°, DIRECT Consortium: Discovery of biomarkers for glycaemic deterioration before and after the
onset of type 2 diabetes: Rationale and design of the epidemiological studies within the IMI DIRECT
Consortium. Diabetologia 57, 1132-1142 (2014)
PLoS ONE 9:e104568 (2014)
Krause, S., Landherr, U., Agardh, C.-D., Hausmann, S., Link, K., Hansen, J.M., Lynch, K.F., Powell, M.,
Furmaniak, J., Rees-Smith, B., Bonifacio, E., Ziegler, A.-G., Lernmark, A., Achenbach, P.°: GAD
autoantibody affinity in adult patients with latent autoimmune diabetes, the study participants of a GAD65
vaccination trial. Diabetes Care 37, 1675-1680 (2014)
page 14 of 247
2015-11-23
#
joint first authors
Krause, S., Beyerlein, A., Winkler, C., Gavrisan, A., Kayser, C., Puff, R., Bonifacio, E., Ziegler, A.-G.°,
Achenbach, P.: Soluble interleukin-2 receptor alpha in preclinical type 1 diabetes. Acta Diabetol. 51,
517-518 (2014)
Kretschmer, A., Möller, G., Lee, H.K., Laumen, H., von Toerne, C., Schramm, K., Prokisch, H., Eyerich,
S., Wahl, S., Baurecht, H., Franke, A., Claussnitzer, M., Eyerich, K., Teumer, A., Milani, L., Klopp, N.,
Hauck, S.M., Illig, T., Peters, A., Waldenberger, M., Adamski, J., Reischl, E., Weidinger, S.°: A common
atopy-associated variant in the TH2 cytokine locus control region impacts transcriptional regulation and alters
SMAD3 and SP1 binding. Allergy 69, 632-642 (2014)
Kronenberg, F., Kollerits, B., Kiechl, S., Lamina, C., Kedenko, L., Meisinger, C., Willeit, J., Huth, C.,
Wietzorrek, G., Altmann, M.E., Thorand, B., Melmer, A., Dähnhardt, D., Santer, P., Rathmann, W.,
Paulweber, B., Koenig, W., Peters, A., Adham, I.M., Dieplinger, H.°: Plasma concentrations of afamin are
associated with the prevalence and development of metabolic syndrome. Circ. Cardiovasc. Genet. 7,
822-829 (2014)
Laxy, M.°, Mielck, A., Hunger, M., Schunk, M., Meisinger, C., Rückert, I.-M., Rathmann, W., Holle, R.:
The association between patient-reported self-management behavior, intermediate clinical outcomes, and
mortality in patients with type 2 diabetes: Results from the KORA-A study. Diabetes Care 37, 1604-1612
(2014)
Linder, K., Schleger, F., Ketterer, C., Fritsche, L., Kiefer-Schmidt, I., Hennige, A.M., Häring, H.-U.,
Preissl, H.°, Fritsche, A.: Maternal insulin sensitivity is associated with oral glucose-induced changes in
fetal brain activity. Diabetologia 57, 1192-1198 (2014)
Linder, K.#, Springer, F.#, Machann, J., Schick, F., Fritsche, A., Häring, H.-U., Blumenstock, G., Ranke,
M.B., Stefan, N., Binder, G., Ehehalt, S.°: Relationships of body composition and liver fat content with insulin
resistance in obesity-matched adolescents and adults. Obesity 13, 733-748 (2014)
Liu, X., Campillos, M.°: Unveiling new biological relationships using shared hits of chemical screening
assay pairs. Bioinformatics 30, i579-i586 (2014)
Lutz, S.Z., Staiger, H., Fritsche, A., Häring, H.-U.°: Antihyperglycaemic therapies and cancer risk. Diab.
Vasc. Dis. Res. 11, 371-389 (2014)
Lutz, S.Z., Franck, O., Böhm, A., Machann, J., Schick, F., Machicao, F., Fritsche, A., Häring, H.-U.°,
Staiger, H.: Common genetic variation in the human CTF1 locus, encoding cardiotrophin-1, determines
insulin sensitivity. PLoS ONE 9:e100391 (2014)
page 15 of 247
2015-11-23
#
joint first authors
Majithia, A.R., Flannick, J., Shahinian, P., Guo, M., Bray, M.A., Fontanillas, P., Gabriel, S.B., GoT2D
Consortium (Gieger, C., Hrabě de Angelis, M., Huth, C., Kriebel, J., Meisinger, C., Meitinger, T., Peters,
A., Rathmann, W., Ried, J.S., Strauch, K., Strom, T.M.), NHGRI JHS/FHS Allelic Spectrum Project,
SIGMA T2D Consortium, T2D-GENES Consortium, Rosen, E.D., Altshuler, D.°: Rare variants in PPARG with
decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes. Proc.
Natl. Acad. Sci. U.S.A. 111, 13127-13132 (2014)
Mathew, S., Krug, S., Skurk, T., Halama, A., Stank, A., Artati, A., Prehn, C., Malek, J.A., Kastenmüller, G.,
Römisch-Margl, W., Adamski, J., Hauner, H., Suhre, K.: Metabolomics of Ramadan fasting: An opportunity
for the controlled study of physiological responses to food intake. J. Transl. Med. 12:161 (2014)
#
#
#
Matthes, M. , Preusse, M. , Zhang, J. , Schechter, J., Mayer, D., Lentes, B., Theis, F.J., Prakash, N.,
Wurst, W.°, Trümbach, D.°: Mouse IDGenes: A reference database for genetic interactions in the
developing mouse brain. Database (Oxford) 2014:bau083 (2014)
Migliorini, A., Bader, E., Lickert, H.°: Islet cell plasticity and regeneration. Mol. Metab. 3, 268–274 (2014)
Mook-Kanamori, D.O., Römisch-Margl, W., Kastenmüller, G., Prehn, C., Petersen, A.K., Illig, T., Gieger,
C., Wang-Sattler, R., Meisinger, C., Peters, A., Adamski, J., Suhre, K.°: Increased amino acids levels and
the risk of developing hypertriglyceridemia in a 7-year follow-up. J. Endocrinol. Invest. 37, 369-374 (2014)
Moreth, K.°, Fischer, R., Fuchs, H., Gailus-Durner, V., Wurst, W., Katus, H.A., Bekeredjian, R., Hrabě de
Angelis, M.°: High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred
mouse strains. J. Comp. Physiol. B 184, 763-775 (2014)
Moruzzi, N.°, Del Sole, M., Fato, R., Gerdes, J.M., Berggren, P.O., Bergamini, C., Brismar, K.: Short and
prolonged exposure to hyperglycaemia in human fibroblasts and endothelial cells: Metabolic and osmotic
effects. Int. J. Biochem. Cell Biol. 53, 66-76 (2014)
Much, D.°, Beyerlein, A.°, Roßbauer, M.°, Hummel, S.°, Ziegler, A.-G.°: Beneficial effects of breastfeeding
in women with gestational diabetes mellitus. Mol. Metab. 3, 284-292 (2014)
Mühlenbruch, K., Ludwig, T., Jeppesen, C., Joost, H.G., Rathmann, W., Meisinger, C., Peters, A., Boeing,
H., Thorand, B., Schulze, M.B.°: Update of the German Diabetes Risk Score and external validation in the
German MONICA/KORA study. Diabetes Res. Clin. Pract. 104, 459-466 (2014)
Mullen, W.°, Saigusa, D., Abe, T., Adamski, J., Mischak, H.: Proteomics and metabolomics as tools to
unravel novel culprits and mechanisms of uremic toxicity: Instrument or hype? Semin. Nephrol. 34, 180-190
(2014)
Neschen, S.°, Scheerer, M., Seelig, A., Huypens, P., Schultheiss, J., Wu, M., Wurst, W., Rathkolb, B.,
Suhre, K., Wolf, E., Beckers, J., Hrabě de Angelis, M.: Metformin supports the antidiabetic effect of a
sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice.
Diabetes 64, 284-290 (2015) [published online 2014]
page 16 of 247
2015-11-23
#
joint first authors
Oelkrug, R., Götze, N., Meyer, C.W., Jastroch, M.°: Antioxidant properties of UCP1 are evolutionary
conserved in mammals and buffer mitochondrial reactive oxygen species. Free Radic. Biol. Med. 77,
210-216 (2014)
Ott, V., Lehnert, H., Staub, J., Wönne, K., Born, J., Hallschmid, M.°: Central nervous insulin administration
does not potentiate the acute glucoregulatory impact of concurrent mild hyperinsulinemia. Diabetes 64,
760-765 (2015) [published online 2014]
Pabst, G., Zimmermann, A.-K., Huth, C., Koenig, W., Ludwig, T., Zierer, A., Peters, A., Thorand, B.°:
Association of low 25-hydroxyvitamin D levels with the frailty syndrome in an aged population: Results from
the KORA-Age Augsburg study. J. Nutr. Health Aging 19, 258-264 (2015) [published online 2014]
Peter, A.°, Kovarova, M., Nadalin, S., Cermak, T., Königsrainer, A., Machicao, F., Stefan, N., Häring, H.-U.,
Schleicher, E.: PNPLA3 variant I148M is associated with altered hepatic lipid composition in humans.
Diabetologia 57, 2103-2107 (2014)
Poschmann, G.°, Seyfarth, K., Besong Agbo, D., Klafki, H.-W., Rozman, J., Wurst, W., Wiltfang, J., Meyer,
H.E., Klingenspor, M., Stühler, K.: High fat diet induced isoform changes of the Parkinson’s disease protein
DJ-1. J. Proteome Res. 13, 2339-2351 (2014)
Reinehr, T.°, Wolters, B., Knop, C., Lass, N., Hellmuth, C., Harder, U., Peissner, W., Wahl, S., Grallert, H.,
Adamski, J., Illig, T., Prehn, C., Yu, Z., Wang-Sattler, R., Koletzko, B.: Changes in the serum metabolite
profile in obese children with weight loss. Eur. J. Nutr. 54, 173-181 (2015) [published online 2014]
Richter, K.°, Breitner, S., Webb, A.R., Huth, C., Thorand, B., Kift, R., Linseisen, J., Schuh, A., Kratzsch,
J., Mielck, A., Weidinger, S., Peters, A., Schneider, A.E.: Influence of external, intrinsic and individual
behaviour variables on serum 25(OH)D in a German survey. J. Photochem. Photobiol. B-Biol. 140, 120-129
(2014)
Ried, J.S.°, Shin, S.Y., Krumsiek, J., Illig, T., Theis, F.J., Spector, T.D., Adamski, J., Wichmann, H.-E.,
Strauch, K., Soranzo, N., Suhre, K., Gieger, C.: Novel genetic associations with serum level metabolites
identified by phenotype set enrichment analyses. Hum. Mol. Genet. 23, 5847-5857 (2014)
Rodriguez, E., Baurecht, H., Wahn, A.F., Kretschmer, A., Hotze, M., Zeilinger, S., Klopp, N., Illig, T.,
Schramm, K., Prokisch, H., Kühnel, B., Gieger, C., Harder, J., Cifuentes, L., Novak, N., Weidinger, S.°: An
integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methylation
associated with atopic dermatitis. J. Invest. Dermatol. 134, 1873-1883 (2014)
Rozman, J.°, Klingenspor, M., Hrabě de Angelis, M.: A review of standardized metabolic phenotyping of
animal models. Mamm. Genome 25, 497-507 (2014)
Rückerl, R.°, Hampel, R., Breitner, S., Cyrys, J., Kraus, U., Carter, J., Dailey, L., Devlin, R.B.,
Diaz-Sanchez, D., Koenig, W., Phipps, R., Silbajoris, R., Soentgen, J., Soukup, J., Peters, A., Schneider,
A.E.: Associations between ambient air pollution and blood markers of inflammation and
coagulation/fibrinolysis in susceptible populations. Environ. Int. 70, 32-49 (2014)
page 17 of 247
2015-11-23
#
joint first authors
#
#
#
#
Schramm, K. , Marzi, C. , Schurmann, C. , Carstensen, M. , Reinmaa, E., Biffar, R., Eckstein, G.N.,
Gieger, C., Grabe, H.J., Homuth, G., Kastenmüller, G., Mägi, R., Metspalu, A., Mihailov, E., Peters, A.,
Petersmann, A., Roden, M., Strauch, K., Suhre, K., Teumer, A., Völker, U., Völzke, H., Wang-Sattler, R.,
Waldenberger, M., Meitinger, T., Illig, T., Herder, C., Grallert, H., Prokisch, H.°: Mapping the genetic
architecture of gene regulation in whole blood. PLoS ONE 9:e93844 (2014)
Schulte, E.C., Schramm, K., Schurmann, C., Lichtner, P., Herder, C., Roden, M., Gieger, C., Peters, A.,
Trenkwalder, C., Högl, B., Frauscher, B., Berger, K., Fietze, I., Gross, N., Stiasny-Kolster, K., Oertel, W.,
Bachmann, C.G., Paulus, W., Zimprich, A., Völzke, H., Schminke, U., Nauck, M., Illig, T., Meitinger, T.,
Müller-Myhsok, B., Prokisch, H., Winkelmann, J.°: Blood cis-eQTL analysis fails to identify novel
association signals among sub-threshold candidates from genome-wide association studies in restless legs
syndrome. PLoS ONE 9:e98092 (2014)
Seyfarth, K., Poschmann, G., Rozman, J., Fromme, T., Rink, N., Hofmann, A., Wurst, W., Stühler, K.,
Klingenspor, M.°: The development of diet-induced obesity and associated metabolic impairments in Dj-1
deficient mice. J. Nutr. Biochem. 26, 75-81 (2015) [published online 2014]
Shin, S.-Y.#, Petersen, A.-K.#, Wahl, S., Zhai, G., Römisch-Margl, W., Small, K.S., Döring, A., Kato, B.S.,
Peters, A., Grundberg, E., Prehn, C., Wang-Sattler, R., Wichmann, H.-E., Hrabě de Angelis, M., Illig, T.,
Adamski, J., Deloukas, P., Spector, T.D., Suhre, K., Gieger, C., Soranzo, N.°: Interrogating causal
pathways linking genetic variants, small molecule metabolites and circulating lipids. Genome Med. 6:25
(2014)
Sinreih, M., Anko, M., Zukunft, S., Adamski, J., Lanisnik Rizner, T.°: Important roles of the AKR1C2 and
SRD5A1 enzymes in progesterone metabolism in endometrial cancer model cell lines. Chem. Biol. Interact.
234, 297-308 (2014)
Spieler, D.#, Kaffe, M.#, Knauf, F.#, Bessa, J., Tena, J.J., Giesert, F.H.H., Schormair, B., Tilch, E., Lee, H.,
Horsch, M., Czamara, D., Karbalai, N., von Toerne, C., Waldenberger, M., Gieger, C., Lichtner, P.,
Claussnitzer, M., Naumann, R., Müller-Myhsok, B., Torres, M., Garrett, L., Rozman, J., Klingenspor, M.,
Gailus-Durner, V., Fuchs, H., Hrabě de Angelis, M., Beckers, J., Hölter, S.M., Meitinger, T., Hauck,
S.M., Laumen, H., Wurst, W., Casares, F., Gómez-Skarmeta, J.L., Winkelmann, J.°: Restless Legs
Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing
telencephalon. Genome Res. 24, 592-603 (2014)
Steiner, S., Daniel, C., Fischer, A., Atreya, I., Hirschmann, S., Waldner, M., Neumann, H., Neurath, M.F.,
Atreya, R., Weigmann, B.°: Cyclosporine A regulates pro-inflammatory cytokine production in ulcerative
colitis. Arch. Immunol. Ther. Exp. 63, 53-63 (2015) [published online 2014]
Stemmer, K.°, Kotzbeck, P., Zani, F., Bauer, M., Neff, C., Müller, T.D., Pfluger, P.T., Seeley, R.J.,
Divanovic, S.: Thermoneutral housing is a critical factor for immune function and diet-induced obesity in
C57BL/6 nude mice. Int. J. Obes. 39, 791-797 (2015) [published online 2014]
page 18 of 247
2015-11-23
#
joint first authors
Stöckl, D.°, Peters, A., Thorand, B., Heier, M., Koenig, W., Seissler, J., Thiery, J., Rathmann, W.,
Meisinger, C.: Reproductive factors, intima media thickness and carotid plaques in a cross-sectional study
of postmenopausal women enrolled in the population-based KORA F4 study. BMC Womens Health 14:17
(2014)
Stribl, C.B.#, Samara, A.#, Trümbach, D.#, Augustin, R., Neumann, M., Fuchs, H., Gailus-Durner, V.,
Hrabě de Angelis, M., Rathkolb, B., Wolf, E., Beckers, J., Horsch, M., Neff, F., Kremmer, E., Koob, S.,
Reichert, A.S., Hans, W., Rozman, J., Klingenspor, M., Aichler, M., Walch, A.K., Becker, L., Klopstock,
T., Glasl, L., Hölter, S.M., Wurst, W., Floss, T.°: Mitochondrial dysfunction and decrease in body weight of
a transgenic knock-in mouse model for TDP-43. J. Biol. Chem. 289, 10769-10784 (2014)
Stumpp, C., Beyerlein, A., Ziegler, A.-G., Bonifacio, E.°: Neonatal and infant beta cell hormone
concentrations in relation to type 1 diabetes risk. Pediatr. Diabetes 15, 528-533 (2014)
Tamayo, T., Claessen, H., Rückert, I.-M., Maier, W., Schunk, M., Meisinger, C., Mielck, A., Holle, R.,
Thorand, B., Narres, M., Moebus, S., Mahabadi, A.A., Pundt, N., Krone, B., Slomiany, U., Erbel, R., Jockel,
K.H., Rathmann, W., Icks, A.°: Treatment pattern of type 2 diabetes differs in two German regions and with
patients' socioeconomic position. PLoS ONE 9:e99773 (2014)
Then, C.°, Kowall, B., Lechner, A., Meisinger, C., Heier, M., Koenig, W., Peters, A., Rathmann, W.,
Seissler, J.: Plasma copeptin is associated with type 2 diabetes in men but not in women in the
population-based KORA F4 study. Acta Diabetol. 52, 103-112 (2015) [published online 2014]
Walker, A., Pfitzner, B., Neschen, S., Kahle, M., Harir, M., Lucio, M., Moritz, F., Tziotis, D., Witting, M.,
Rothballer, M., Engel, M., Schmid, M., Endesfelder, D., Klingenspor, M., Rattei, T., zu Castell, W.,
Hrabě de Angelis, M., Hartmann, A., Schmitt-Kopplin, P.°: Distinct signatures of host-microbial
meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet. ISME J. 8, 2380-2396
(2014)
Walker, A., Lucio, M., Pfitzner, B., Scheerer, M.F., Neschen, S., Hrabě de Angelis, M., Hartmann, A.,
Schmitt-Kopplin, P.°: The importance of sulfur-containing metabolites in discriminating fecal extracts
between normal and type 2 diabetic mice. J. Proteome Res. 13, 4220-4231 (2014)
Am. J. Hum. Genet. 94, 710-720 (2014)
Wientzek, A.°, Floegel, A., Knüppel, S., Vigl, M., Drogan, D., Adamski, J., Pischon, T., Boeing, H.: Serum
metabolites related to cardiorespiratory fitness, physical activity energy expenditure, sedentary time and
vigorous activity. Int. J. Sport Nutr. Exerc. Metab. 24, 215-226 (2014)
page 19 of 247
2015-11-23
#
joint first authors
#
#
Yang, D. , Lutter, D. , Burtscher, I., Uetzmann, L., Theis, F.J.°, Lickert, H.°: miR-335 promotes
mesendodermal lineage segregation and shapes a transcription factor gradient in the endoderm.
Development 141, 514-525 (2014)
Yousri, N.A., Kastenmüller, G., Gieger, C., Shin, S.-Y., Erte, I., Menni, C., Peters, A., Meisinger, C.,
Mohney, R.P., Illig, T., Adamski, J., Soranzo, N., Spector, T.D., Suhre, K.°: Long term conservation of
human metabolic phenotypes and link to heritability. Catal. Lett. 10, 1005-1017 (2014)
page 20 of 247
2015-11-23
#
joint first authors
German Center for Lung Research
Hoogendoorn, M.°, Feenstra, T.L., Asukai, Y., Borg, S., Hansen, R.N., Jansson, S.A., Samyshkin, Y.,
Wacker, M., Briggs, A.H., Lloyd, A., Sullivan, S.D., Rutten-van Mölken, M.P.: Cost-effectiveness models for
chronic obstructive pulmonary disease: Cross-model comparison of hypothetical treatment scenarios. Value
Health 17, 525-536 (2014)
online 2014]
Pokhrel, S.°, Evers, S., Leidl, R., Trapero-Bertran, M., Kalo, Z., Vries, H.d., Crossfield, A., Andrews, F.,
Rutter, A., Coyle, K., Lester-George, A., West, R., Owen, L., Jones, T., Vogl, M., Radu-Loghin, C., Voko, Z.,
Huic, M., Coyle, D.: EQUIPT: Protocol of a comparative effectiveness research study evaluating
cross-context transferability of economic evidence on tobacco control. BMJ Open 4:e006945 (2014)
Rottenkolber, M.°, Rottenkolber, D., Fischer, R., Ibáñez, L., Fortuny, J., Ballarin, E., Sabaté, M., Ferrer, P.,
Thürmann, P., Hasford, J., Schmiedl, S.: Inhaled beta-2-agonists/muscarinic antagonists and acute
myocardial infarction in COPD patients. Respir. Med. 108, 1075-1090 (2014)
Wacker, M.E.°, Hunger, M., Karrasch, S., Heinrich, J., Peters, A., Schulz, S., Holle, R.: Health-related
quality of life and chronic obstructive pulmonary disease in early stages - longitudinal results from the
population-based KORA cohort in a working age population. BMC Pulm. Med. 14:134 (2014)
page 21 of 247
2015-11-23
#
joint first authors
Institute for Allergy Research
#
#
Balzer, L. , Pennino, D. , Blank, S., Seismann, H., Darsow, U., Schnedler, M., McIntyre, M., Ollert, M.,
Durham, S.R., Spillner, E., Ring, J., Cifuentes, L.: Basophil activation test using recombinant allergens:
Highly specific diagnostic method complementing routine tests in wasp venom allergy. PLoS ONE 9:e108619
(2014)
Boehme, M.W.J.°, Kompauer, I., Weidner, U., Piechotowski, I., Gabrio, T., Behrendt, H.:
Atemwegsbeschwerden und Sensibilisierungen gegen Pollen von Ambrosia artemisiifolia und Beifuß bei
Erwachsenen in Süd-West-Deutschland. Dtsch. Med. Wochenschr. 138, 1651-1658 (2013)
#
#
Brosch, S. , Dietze-Schwonberg, K. , Lopez Kostka, S., Lorenz, B., Haak, S., Becher, B., von Stebut, E.°:
Disease control in cutaneous leishmaniasis is independent of IL-22. J. Invest. Dermatol. 135, 308-311 (2015)
Darsow, U., Brockow, K., Pfab, F., Jakob, T., Petersson, C.J., Borres, M.P., Ring, J., Behrendt, H.,
Huss-Marp, J.°: Heterogeneity of molecular sensitization profiles in grass pollen allergy - implications for
immunotherapy? Clin. Exp. Allergy 44, 778-786 (2014)
Derycke, L., Eyerich, S., van Crombruggen, K., Pérez-Novo, C., Holtappels, G., Deruyck, N., Gevaert, P.,
Bachert, C.°: Mixed T helper cell signatures in chronic rhinosinusitis with and without polyps. PLoS ONE
9:e97581 (2014)
Eberlein, B.°, Hann, R., Eyerich, S., Pennino, D., Ring, J., Schmidt-Weber, C.B., Buters, J.: Optimizing of
the basophil activation test: Comparison of different basophil identification markers. Cytometry B Clin.
Cytom. 88, 183-189 (2015) [published online 2014]
El-Kelish, A., Zhao, F., Heller, W., Durner, J., Winkler, J.B., Behrendt, H., Traidl-Hoffmann, C., Horres,
R., Pfeifer, M., Frank, U.°, Ernst, D.: Ragweed (Ambrosia artemisiifolia) pollen allergenicity: SuperSAGE
transcriptomic analysis upon elevated CO2 and drought stress. BMC Plant Biol. 14:176 (2014)
Eyerich, S.°, Zielinski, E.C.: Defining Th-cell subsets in a classical and tissue-specific manner: Examples
from the skin. Eur. J. Immunol. 44, 3475-3483 (2014)
Garzorz, N.°, Papanagiotou, V., Atenhan, A., Andres, C., Eyerich, S., Eyerich, K., Ring, J., Brockow, K.:
Pyoderma gangrenosum, Acne, Psoriasis, Arthritis and Suppurative Hidradenitis (PAPASH)-syndrome: A
new entity within the spectrum of autoinflammatory syndromes? J. Eur. Acad. Dermatol. Venereol., DOI:
10.1111/jdv.12631 (2014)
Gruzieva, O.°, Gehring, U., Aalberse, R., Agius, R.M., Beelen, R., Behrendt, H., Bellander, T., Birk, M., de
Jongste, J.C., Fuertes, E., Heinrich, J., Hoek, G., Klümper, C., Koppelman, G., Korek, M., Krämer, U.,
Lindley, S., Mölter, A., Simpson, A., Standl, M., van Hage, M., von Berg, A., Wijga, A., Brunekreef, B.,
Pershagen, G.: Meta-analysis of air pollution exposure association with allergic sensitization in European
birth cohorts. J. Allergy Clin. Immunol. 133, 767-776 (2014)
page 22 of 247
2015-11-23
#
joint first authors
Hummelsberger, J.°, Wullinger, M., Ortiz, M.R., Pfab, F., Irnich, D., Hauswald, B., Gleditsch, J.M., Hempen,
C.H., Binting, S., Brinkhaus, B.: Akupunktur bei Patienten mit allergischer Rhinitis - Analyse der
Studienintervention und Syndrommuster der randomisierten Multicenter-Studie ACUSAR. Chin. Med. 29,
63-77 (2014)
Hummelsberger, J.°, Wullinger, M., Ortiz, M.R., Pfab, F., Irnich, D., Hauswald, B., Gleditsch, J.M., Hempen,
C.H., Binting, S., Brinkhaus, B.: Akupunktur bei Patienten mit allergischer Rhinitis: Analyse der
Studienintervention und Syndrommuster der randomisierten Multicenter Studie (ACUSAR). Dt. Ztschr. f.
Akup. 57, 6-11 (2014)
#
#
Jaeger, T. °, Mourantchanian, V. , Gutermuth, J., Hein, R., Andres, C., Ring, J., Brockow, K.: Periorbital
edema. Int. J. Dermatol. 53, 937-939 (2014)
2014]
Kurz, C.°, Wunderlich, S., Spieler, D., Schwaiger, B.J., Andres, C., Traidl-Hoffmann, C., Ilg, R.: Acute
transverse myelitis and psoriasiform dermatitis associated with Sjoegren's syndrome: A case report. BMC
Res. Notes 7:580 (2014)
Marzaioli, V., Aguilar-Pimentel, J.A., Weichenmeier, I., Luxenhofer, G., Wiemann, M., Landsiedel, R.,
Wohlleben, W., Eiden, S., Mempel, M., Behrendt, H., Schmidt-Weber, C.B., Gutermuth, J., Alessandrini,
F.°: Surface modifications of silica nanoparticles are crucial for their inert versus proinflammatory and
immunomodulatory properties. Int. J. Nanomed. 9, 2815-2832 (2014)
Quaranta, M., Eyerich, S., Knapp, B., Nasorri, F., Scarponi, C., Mattii, M., Garzorz, N., Harlfinger, A.T.,
Jaeger, T., Grosber, M., Pennino, D., Mempel, M., Schnopp, C., Theis, F.J., Albanesi, C., Cavani, A.,
Schmidt-Weber, C.B., Ring, J., Eyerich, K.°: Allergic contact dermatitis in psoriasis patients: Typical,
delayed, and non-interacting. PLoS ONE 9:e101814 (2014)
page 23 of 247
2015-11-23
#
joint first authors
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Quaranta, M. , Knapp, B. , Garzorz, N., Mattii, M., Pullabhatla, V., Pennino, D., Andres, C.,
Traidl-Hoffmann, C., Cavani, A., Theis, F.J., Ring, J., Schmidt-Weber, C.B., Eyerich, S., Eyerich, K.°:
Intraindividual genome expression analysis reveals a specific molecular signature of psoriasis and eczema.
Sci. Transl. Med. 6:244ra90 (2014)
Raulf, M.°, Buters, J., Chapman, M., Cecchi, L., de Blay, F., Doekes, G., Eduard, W., Heederik, D.,
Jeebhay, M., Kespohl, S., Krop, E.J., Moscato, G., Pala, G., Quirce, S., Sander, I., Schlünssen, V.,
Sigsgaard, T., Walusiak-Skorupa, J., Wiszniewska, M., Wouters, I.M., Annesi-Maesano, I.: Monitoring of
occupational and environmental aeroallergens-EAACI position paper. Allergy 69, 1280-1299 (2014)
Spillner, E.°, Blank, S., Jakob, T.: Hymenoptera allergens: From venom to "venome". Front. Immunol. 5:77
(2014)
Staumont-Salle, D., Fleury, S., Lazzari, A., Molendi-Coste, O., Hornez, N., Lavogiez, C., Kanda, A., Wartelle,
J., Fries, A., Pennino, D., Mionnet, C., Prawitt, J., Bouchaert, E., Delaporte, E., Glaichenhaus, N., Staels, B.,
Julia, V., Dombrowicz, D.°: CX3CL1 (fractalkine) and its receptor CX3CR1 regulate atopic dermatitis by
controlling effector T cell retention in inflamed skin. J. Exp. Med. 211, 1185-1196 (2014)
van Vaerenbergh, M., de Smet, L., Rafei-Shamsabadi, D., Blank, S., Spillner, E., Ebo, D.G., Devreese, B.,
Jakob, T., de Graaf, D.C.°: IgE recognition of chimeric isoforms of the honeybee (Apis mellifera) venom
allergen Api m 10 evaluated by protein array technology. Mol. Immunol. 63, 449-455 (2015)
von Sonnenburg, F., Perona, P., Darsow, U., Ring, J., von Krempelhuber, A., Vollmar, J., Roesch, S.,
Baedeker, N., Kollaritsch, H., Chaplin, P.°: Safety and immunogenicity of modified vaccinia Ankara as a
smallpox vaccine in people with atopic dermatitis. Vaccine 32, 5696-5702 (2014)
Zink, A., Ring, J., Brockow, K.°: Kofaktorgetriggerte Nahrungsmittelanaphylaxie. Allergologie 37, 258-264
(2014)
Zirbs, M.°, Reindel, U., Hermann, K., Church, M.K., Behrendt, H., Ring, J., Brockow, K.: Reduced skin
reactivity to vasoconstrictor and vasodilator substances in atopic eczema. Eur. J. Dermatol. 23, 812-819
(2013)
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Institute for Pancreatic Beta Cell Research
Beyerlein, A., Chmiel, R., Hummel, S., Winkler, C., Bonifacio, E., Ziegler, A.-G.°: Timing of gluten
introduction and islet autoimmunity in young children: Updated results from the BABYDIET study. Diabetes
Care 37, e194-e195 (2014)
Chmiel, R., Giannopoulou, E.Z., Winkler, C., Achenbach, P., Ziegler, A.-G.°, Bonifacio, E.: Progression
from single to multiple islet autoantibodies often occurs soon after seroconversion: Implications for early
screening. Diabetologia 58, 411-413 (2015) [published online 2014]
Elding Larsson, H.°, Vehik, K., Gesualdo, P., Akolkar, B., Hagopian, W., Krischer, J.P., Lernmark, A.,
Rewers, M., Simell, O., She, J.-X., Ziegler, A.-G., Haller, M.J., TEDDY Study Group (Beyerlein, A.,
Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Kersting, M., Knopff, A., Koletzko, S., Peplow, C.,
Roth, R., Stock, J., Strauss, E., Warncke, K., Winkler, C.): Children followed in the TEDDY study are
diagnosed with type 1 diabetes at an early stage of disease. Pediatr. Diabetes 15, 118-126 (2014)
Endesfelder, D.#, zu Castell, W.#, Ardissone, A., Davis-Richardson, A.G., Achenbach, P., Hagen, M.,
Fuchs, Y.F.#, Adler, K.#, Lindner, A., Karasinsky, A., Wilhelm, C., Weigelt, M., Balke, H., Förtsch, K.,
vaccination induce CD8+ T cell mediated autoimmune diabetes in the RIP-CD80GP mouse. Clin. Exp.
Immunol. 176, 199-206 (2014)
Hummel, S.°, Vehik, K., Uusitalo, U., McLeod, W., Aronsson, C.A., Frank, N., Gesualdo, P., Yang, J., Norris,
J.M., Virtanen, S.M., TEDDY Study Group (Ziegler, A.-G., Beyerlein, A., Bonifacio, E., Hummel, M.,
Foterek, K., Kersting, M., Knopff, A., Koletzko, S., Peplow, C., Roth, R., Stock, J., Strauss, E.,
Warncke, K., Winkler, C.): Infant feeding patterns in families with a diabetes history - observations from The
Environmental Determinants of Diabetes in the Young (TEDDY) birth cohort study. Public Health Nutr. 17,
2853-2862 (2014)
Kemppainen, K.M., Ardissone, A.N., Davis-Richardson, A.G., Fagen, J.R., Gano, K.A., León-Novelo, L.G.,
Vehik, K., Casella, G., Simell, O., Ziegler, A.-G., Rewers, M.J., Lernmark, A., Hagopian, W., She, J.X.,
Krischer, J.P., Akolkar, B., Schatz, D.A., Atkinson, M.A., Triplett, E.W.°, TEDDY Study Group (Beyerlein, A.,
Roth, R., Stock, J., Strauss, E., Warncke, K., Winkler, C.): Early childhood gut microbiomes show strong
geographic differences among subjects at high risk for type 1 diabetes. Diabetes Care 38, 329-332 (2015)
page 25 of 247
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517-518 (2014)
Lee, H.S., Burkhardt, B.R., McLeod, W., Smith, S., Eberhard, C., Lynch, K., Hadley, D., Rewers, M., Simell,
O., She, J.X., Hagopian, B., Lernmark, A., Akolkar, B., Ziegler, A.-G., Krischer, J.P.°, TEDDY Study Group
(Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Kersting, M., Knopff, A., Koletzko,
S., Peplow, C., Roth, R., Stock, J., Strauss, E., Warncke, K., Winkler, C.): Biomarker discovery study
design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study.
Diabetes Metab. Res. Rev. 30, 424-434 (2014)
Liu, E., Lee, H.S., Aronsson, C.A., Hagopian, W.A., Koletzko, S., Rewers, M.J., Eisenbarth, G.S., Bingley,
P.J., Bonifacio, E., Simell, V., Agardh, D.°, TEDDY Study Group (Ziegler, A.-G., Beyerlein, A., Bonifacio,
E., Hummel, M., Hummel, S., Foterek, K., Kersting, M., Knopff, A., Koletzko, S., Peplow, C., Roth, R.,
Stock, J., Strauss, E., Warncke, K., Winkler, C.): Risk of pediatric celiac disease according to HLA
haplotype and country. N. Engl. J. Med. 371, 42-49 (2014)
Roth, R.°, Lynch, K., Lernmark, B., Baxter, J., Simell, T., Smith, L., Swartling, U., Ziegler, A.-G., Johnson,
S.B., TEDDY Study Group (Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Kersting,
M., Knopff, A., Koletzko, S., Peplow, C., Stock, J., Strauss, E., Warncke, K., Winkler, C.): Maternal
anxiety about a child's diabetes risk in the TEDDY study: The potential role of life stress, postpartum
depression, and risk perception. Pediatr. Diabetes 16, 287-298 (2014)
Törn, C.°, Hadley, D., Lee, H.S., Hagopian, W., Lernmark, A., Simell, O., Rewers, M., Ziegler, A.-G., Schatz,
D., Akolkar, B., Onengut-Gumuscu, S., Chen, W.M., Toppari, J., Mykkänen, J., Ilonen, J., Rich, S.S., She,
J.X., Steck, A.K., Krischer, J., TEDDY Study Group (Beyerlein, A., Bonifacio, E., Hummel, M., Hummel,
S., Foterek, K., Kersting, M., Knopff, A., Koletzko, S., Peplow, C., Roth, R., Stock, J., Strauss, E.,
Warncke, K., Winkler, C.): Role of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the
TEDDY study. Diabetes 64, 1818-1829 (2015) [published online 2014]
Winkler, C.#, Krumsiek, J.#, Buettner, F., Angermüller, C., Giannopoulou, E.Z., Theis, F.J., Ziegler,
A.-G.°, Bonifacio, E.°: Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1
diabetes. Diabetologia 57, 2521-2529 (2014)
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Yang, J.°, Lernmark, A., Uusitalo, U.M., Lynch, K.F., Veijola, R., Winkler, C., Larsson, H.E., Rewers, M.,
She, J.X., Ziegler, A.-G., Simell, O.G., Hagopian, W.A., Akolkar, B., Krischer, J.P., Vehik, K., TEDDY Study
Group (Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Kersting, M., Knopff, A.,
Koletzko, S., Peplow, C., Roth, R., Stock, J., Strauss, E., Warncke, K.): Prevalence of obesity was related
to HLA-DQ in 2-4 year old children at genetic risk for type 1 diabetes. Int. J. Obes. 38, 1491-1496 (2014)
page 27 of 247
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joint first authors
Institute of Biochemical Plant Pathology
Arango, L., Buddrus-Schiemann, K., Opelt, K., Lueders, T., Haesler, F., Schmid, M., Ernst, D.,
Hartmann, A.°: Effects of glyphosate on the bacterial community associated with roots of transgenic
®
Roundup Ready soybean. Eur. J. Soil Biol. 63, 41-48 (2014)
Breitenbach, H.H.#, Wenig, M.#, Wittek, F., Jordá, L., Maldonado-Alconada, A.M., Sarioglu, H., Colby,
T.V., Knappe, C., Bichlmeier, M., Pabst, E., Mackey, D.M., Parker, J.E., Vlot, A.C.°: Contrasting roles of
the apoplastic aspartyl protease APOPLASTIC, ENHANCED DISEASE SUSCEPTIBILITY1-DEPENDENT1
and LEGUME LECTIN-LIKE PROTEIN1 in arabidopsis systemic acquired resistance. Plant Physiol. 165,
791-809 (2014)
Chaki, M., Kovacs, I., Spannagl, M., Lindermayr, C.°: Computational prediction of candidate proteins for
S-nitrosylation in Arabidopsis thaliana. PLoS ONE 9:e110232 (2014)
Dey, S., Wenig, M., Langen, G., Sharma, S., Kugler, K.G., Knappe, C., Hause, B., Bichlmeier, M.,
Babaeizad, V., Imani, J., Janzik, I., Stempfl, T., Hueckelhoven, R., Kogel, K.H., Mayer, K.F.X., Vlot, A.C.°:
Bacteria-triggered systemic immunity in barley appears to be associated with WRKY and ETHYLENE
RESPONSIVE FACTORs but not with salicylic acid. Plant Physiol. 166, 2133-2151 (2014)
Gao, P.#, Loeffler, T.S.#, Honsel, A., Kruse, J.°, Krol, E., Scherzer, S., Kreuzer, I., Bemm, F., Buegger, F.,
Burzlaff, T., Hedrich, R., Rennenberg, H.: Integration of trap- and root-derived nitrogen nutrition of
carnivorous Dionaea muscipula. New Phytol. 205, 1320-1329 (2015) [published online 2014]
Ghirardo, A., Wright, L.P., Bi, Z., Rosenkranz, M., Pulido, P., Rodríguez-Concepción, M., Niinemets, U.,
Brüggemann, N., Gershenzon, J., Schnitzler, J.-P.°: Metabolic flux analysis of plastidic isoprenoid
biosynthesis in poplar leaves emitting and non-emitting isoprene. Plant Physiol. 165, 37-51 (2014)
Hofmann, A., Fischer, D., Hartmann, A., Schmid, M.°: Colonization of plants by human pathogenic
bacteria in the course of organic vegetable production. Front. Microbiol. 5:191 (2014)
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Holzmeister, C. , Gaupels, F. , Geerlof, A., Sarioglu, H., Sattler, M., Durner, J., Lindermayr, C.°:
Differential inhibition of Arabidopsis superoxide dismutases by peroxynitrite-mediated tyrosine nitration. J.
Exp. Bot. 66, 989-999 (2015) [published online 2014]
Kaling, M., Kanawati, B., Ghirardo, A., Albert, A., Winkler, J.B., Heller, W., Barta, C., Loreto, F.,
Schmitt-Kopplin, P., Schnitzler, J.-P.°: UV-B mediated metabolic rearrangements in poplar revealed by
non-targeted metabolomics. Plant Cell Environ. 38, 892-904 (2015) [published online 2014]
Kerner, R.C.°, Delgado-Eckert, E., Ernst, D., Dupuy, J.W., Thorsten Grams, E.E., Winkler, J.B.,
Lindermayr, C., Müller-Starck, G.: Large-scale protein analysis of European beech trees following four
vegetation periods of twice ambient ozone exposure. J. Proteomics 109, 417-435 (2014)
page 28 of 247
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Institute of Biochemical Plant Pathology
Kreuzwieser, J.°, Scheerer, U., Kruse, J., Burzlaff, T., Honsel, A., Alfarraj, S., Georgiev, P., Schnitzler, J.-P.,
Ghirardo, A., Kreuzer, I., Hedrich, R., Rennenberg, H.: The Venus flytrap attracts insects by the release of
volatile organic compounds. J. Exp. Bot. 65, 755-766 (2014)
Leiminger, J.H.°, Bäßler, E., Knappe, C., Bahnweg, G., Hausladen, H.: Quantification of disease
progression of Alternaria spp. on potato using real-time PCR. Eur. J. Plant Path. 141, 295-309 (2015)
Sambade, A., Findlay, K., Schäffner, A., Lloyd, C.W., Buschmann, H.°: Actin-dependent and -independent
functions of cortical microtubules in the differentiation of Arabidopsis leaf trichomes. Plant Cell 26, 1629-1644
(2014)
Vanzo, E., Ghirardo, A., Merl-Pham, J., Lindermayr, C., Heller, W., Hauck, S.M., Durner, J., Schnitzler,
J.-P.°: S-nitroso-proteome in poplar leaves in response to acute ozone stress. PLoS ONE 9:e106886 (2014)
Velikova, V.B., Ghirardo, A., Vanzo, E., Merl, J., Hauck, S.M., Schnitzler, J.-P.°: Genetic manipulation of
isoprene emissions in poplar plants remodels the chloroplast proteome. J. Proteome Res. 13, 2005-2018
(2014)
Wittek, F., Hoffmann, T., Kanawati, B., Bichlmeier, M., Knappe, C., Wenig, M., Schmitt-Kopplin, P.,
Parker, J.E., Schwab, W., Vlot, A.C.°: Arabidopsis ENHANCED DISEASE SUSCEPTIBILITY1 promotes
systemic acquired resistance via azelaic acid and its precursor 9-oxo nonanoic acid. J. Exp. Bot. 65,
5919-5931 (2014)
Wittek, F., Kanawati, B., Wenig, M., Hoffmann, T., Franz-Oberdorf, K., Schwab, W., Schmitt-Kopplin, P.,
Vlot, A.C.°: Folic acid induces salicylic acid-dependent immunity in Arabidopsis and enhances susceptibility
to Alternaria brassicicola. Mol. Plant Pathol. 16, 616-622 (2015) [published online 2014]
Wright, L.P.°, Rohwer, J.M., Ghirardo, A., Hammerbacher, A., Ortiz, M., Raguschke, B., Schnitzler, J.-P.,
Gershenzon, J., Phillips, M.A.°: 1-Deoxyxylulose 5-phosphate synthase controls flux through the
2-C-methylerythritol 4-phosphate pathway in Arabidopsis thaliana. Plant Physiol. 165, 1488-1504 (2014)
page 29 of 247
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Institute of Bioinformatics and Systems Biology
Andor, N., Harness, J.V., Müller, S., Mewes, H.-W., Petritsch, C.°: EXPANDS: Expanding ploidy and allele
frequency on nested subpopulations. Bioinformatics 30, 50-60 (2014)
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Arking, D.E. , Pulit, S.L. , Crotti, L., van der Harst, P., Munroe, P.B., Koopmann, T.T., Sotoodehnia, N.,
Rossin, E.J., Morley, M., Wang, X., Johnson, A.D., Lundby, A., Gudbjartsson, D.F., Noseworthy, P.A.,
Eijgelsheim, M., Bradford, Y., Tarasov, K.V., Dörr, M., Müller-Nurasyid, M., Lahtinen, A.M., Nolte, I.M.,
Smith, A.V., Bis, J.C., Isaacs, A., Newhouse, S.J., Evans, D.S., Post, W.S., Waggott, D., Lyytikäinen, L.P.,
Hicks, A.A., Eisele, L., Ellinghaus, D., Hayward, C., Navarro, P., Ulivi, S., Tanaka, T., Tester, D.J., Chatel, S.,
Gustafsson, S., Kumari, M., Morris, R.W., Naluai, A.T., Padmanabhan, S., Kluttig, A., Strohmer, B.,
Panayiotou, A.G., Torres, M., Knoflach, M., Hubácek, J.A., Slowikowski, K., Raychaudhuri, S., Kumar, R.D.,
Harris, T.B., Launer, L.J., Shuldiner, A.R., Alonso, A., Bader, J.S., Ehret, G., Huang, H., Kao, W.H., Strait,
J.B., Macfarlane, P.W., Brown, M., Caulfield, M.J., Samani, N.J., Kronenberg, F., Willeit, J., CARE
Consortium, COGENT Consortium, Smith, J.G., Greiser, K.H., Meyer zu Schwabedissen, H.E., Werdan, K.,
Carella, M., Zelante, L., Heckbert, S.R., Psaty, B.M., Rotter, J.I., Kolcic, I., Polasek, O., Wright, A.F., Griffin,
M., Daly, M.J., Arnar, D.O., Holm, H., Thorsteinsdottir, U., eMERGE Consortium, Denny, J.C., Roden, D.M.,
Zuvich, R.L., Emilsson, V., Plump, A.S., Larson, M.G., O'Donnell, C.J., Yin, X.Y., Bobbo, M., d'Adamo, A.P.,
Iorio, A., Sinagra, G., Carracedo, A., Cummings, S.R., Nalls, M.A., Jula, A., Kontula, K.K., Marjamaa, A.,
Oikarinen, L., Perola, M., Porthan, K., Erbel, R., Hoffmann, P., Jockel, K.H., Kälsch, H., Nöthen, M.M.,
HRGEN Consortium, den Hoed, M., Loos, R.J., Thelle, D.S., Gieger, C., Meitinger, T., Perz, S., Peters, A.,
Prucha, H., Sinner, M.F., Waldenberger, M., de Boer, R.A., Franke, L., van der Vleuten, P.A., Beckmann,
B.M., Martens, E., Bardai, A., Hofman, N., Wilde, A.A., Behr, E.R., Dalageorgou, C., Giudicessi, J.R.,
Medeiros-Domingo, A., Barc, J., Kyndt, F., Probst, V., Ghidoni, A., Insolia, R., Hamilton, R.M., Scherer, S.W.,
Brandimarto, J., Margulies, K., Moravec, C.E., Fabiola, C., Fuchsberger, C., O'Connell, J.R., Lee, W.K.,
Watt, G.C., Campbell, H., Wild, S.H., El Mokhtari, N.E., Frey, N., Asselbergs, F.W., Leach, I.M., Navis, G.,
van den Berg, M.P., van Veldhuisen, D.J., Kellis, M., Krijthe, B.P., Franco, O.H., Hofman, A., Kors, J.A.,
Uitterlinden, A.G., Witteman, J.C., Kedenko, L., Lamina, C., Oostra, B.A., Abecasis, G.R., Lakatta, E.G.,
Mulas, A., Orrù, M., Schlessinger, D., Uda, M., Markus, M.R., Völker, U., Snieder, H., Spector, T.D., Ärnlöv,
J., Lind, L., Sundström, J., Syvanen, A.C., Kivimaki, M., Kähönen, M., Mononen, N., Raitakari, O.T., Viikari,
J.S., Adamkova, V., Kiechl, S., Brion, M.J., Nicolaides, A.N., Paulweber, B., Haerting, J., Dominiczak, A.F.,
Nyberg, F., Whincup, P.H., Hingorani, A.D., Schott, J.J., Bezzina, C.R., Ingelsson, E., Ferrucci, L., Gasparini,
P., Wilson, J.F., Rudan, I., Franke, A., Mühleisen, T.W., Pramstaller, P.P., Lehtimäki, T.J., Paterson, A.D.,
Parsa, A., Liu, Y., van Duijn, C.M., Siscovick, D.S., Gudnason, V., Jamshidi, Y., Salomaa, V., Felix, S.B.,
Sanna, S., Ritchie, M.D., Stricker, B.H., Stefansson, K., Boyer, L.A., Cappola, T.P., Olsen, J.V., Lage, K.,
Schwartz, P.J., Kääb, S., Chakravarti, A., Ackerman, M.J., Pfeufer, A., de Bakker, P.I., Newton-Cheh, C.°:
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial
repolarization. Nat. Genet. 46, 826-836 (2014)
Arnold, M.#, Raffler, J.#, Pfeufer, A., Suhre, K., Kastenmüller, G.°: SNiPA: An interactive, genetic
variant-centered annotation browser. Bioinformatics 31, 1334-1336 (2015) [published online 2014]
page 30 of 247
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Arnold, R., Goldenberg, F., Mewes, H.-W., Rattei, T.°: SIMAP - the database of all-against-all protein
sequence similarities and annotations with new interfaces and increased coverage. Nucleic Acids Res. 42,
D279-D284 (2014)
Bettecken, T.°, Pfeufer, A., Sudbrak, R., Siddiqui, R., Franke, A., Wienker, T.F., Krawczak, M.: Next
Generation Sequencing in der diagnostischen Praxis. Med. Genet. 26, 21-27 (2014)
Budziszewska, M., Wieczorek, P., Zhang, Y., Frishman, D., Obrepalska-Steplowska, A.°: Genetic variability
within the Polish tomato torrado virus Kra isolate caused by deletions in the 3'-untranslated region of
genomic RNA1. Virus Res. 185, 47-52 (2014)
(2014)
Do, K.T., Kastenmüller, G., Mook-Kanamori, D.O., Yousri, N.A., Theis, F.J., Suhre, K., Krumsiek, J.°:
Network-based approach for analyzing intra- and interfluid metabolite associations in human blood, urine,
and saliva. J. Proteome Res. 14, 1183-1194 (2015) [published online 2014]
Ellwanger, D.C.°, Leonhardt, J., Mewes, H.-W.: Large-scale modeling of condition-specific gene regulatory
networks by information integration and inference. Nucleic Acids Res. 42:e166 (2014)
Frangoulidis, D.°, Walter, M., Antwerpen, M., Zimmermann, P., Janowetz, B., Alex, M., Böttcher, J.,
Henning, K., Hilbert, A., Ganter, M., Runge, M., Münsterkötter, M., Splettstoesser, W.D., Hanczaruk, M.:
Molecular analysis of Coxiella burnetii in Germany reveals evolution of unique clonal clusters. Int. J. Med.
Microbiol. 304, 868-876 (2014)
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Ganesh, S.K. °, Chasman, D.I. , Larson, M.G. , Guo, X. , Verwoert, G. , Bis, J.C. , Gu, X. , Smith, A.V. ,
Yang, M.L., Zhang, Y., Ehret, G., Rose, L.M., Hwang, S.J., Papanicolau, G.J., Sijbrands, E.J., Rice, K.,
Eiriksdottir, G., Pihur, V., Ridker, P.M., Vasan, R.S., Newton-Cheh, C., Global BPgen Consortium
(Chakravarti, A., Döring, A., Gieger, C., Illig, T., Meitinger, T., Pfeufer, A., Wichmann, H.-E.), Raffel, L.J.,
Amin, N., Rotter, J.I., Liu, K., Launer, L.J., Xu, M., Caulfield, M., Morrison, A.C., Johnson, A.D., Vaidya, D.,
Dehghan, A., Li, G., Bouchard, C., Harris, T.B., Zhang, H., Boerwinkle, E., Siscovick, D.S., Gao, W.,
Uitterlinden, A.G., Rivadeneira, F., Hofman, A., Willer, C.J., Franco, O.H., Huo, Y., Witteman, J.C., Munroe,
P.B., Gudnason, V., Palmas, W., van Duijn, C., Fornage, M., Levy, D., Psaty, B.M.: Effects of long-term
averaging of quantitative blood pressure traits on the detection of genetic associations. Am. J. Hum. Genet.
95, 49-65 (2014)
Grabe, H.J.°, Assel, H., Bahls, T.A., Dörr, M., Endlich, K.H., Endlich, N., Erdmann, P., Ewert, R., Felix, S.B.,
Fiene, B., Fischer, T., Fleßa, S., Friedrich, N., Gadebusch-Bondio, M., Salazar, M.G., Hammer, E., Haring,
R., Havemann, C., Hecker, M., Hoffmann, W.J., Holtfreter, B., Kacprowski, T., Klein, K., Kocher, T.M., Kock,
H., Krafczyk, J., Kuhn, J., Langanke, M., Lendeckel, U., Lerch, M.M., Lieb, W., Lorbeer, R., Mayerle, J.,
Meissner, K., Meyer zu Schwabedissen, H.E., Nauck, M.A., Ott, K., Rathmann, W.G., Rettig, R., Richardt,
C., Saljé, K., Schminke, U., Schulz, A., Schwab, M., Siegmund, W., Stracke, S., Suhre, K., Ueffing, M.,
Ungerer, S., Völker, U., Völzke, H., Wallaschofski, H., Werner, V., Zygmunt, M.T., Kroemer, H.K.: Cohort
profile: Greifswald approach to individualized medicine (GANI_MED). J. Transl. Med. 12:144 (2014)
Kapoor, A., Sekar, R.B., Hansen, N.F., Fox-Talbot, K., Morley, M., Pihur, V., Chatterjee, S., Brandimarto, J.,
Moravec, C.S., Pulit, S.L., QT Interval International GWAS Consortium, Pfeufer, A., Mullikin, J.C., Ross, M.,
Green, E.D., Bentley, D., Newton-Cheh, C., Boerwinkle, E., Tomaselli, G.F., Cappola, T.P., Arking, D.E.,
Halushka, M.K., Chakravarti, A.°: An enhancer polymorphism at the cardiomyocyte intercalated disc protein
NOS1AP locus is a major regulator of the QT interval. Am. J. Hum. Genet. 94, 854-869 (2014)
Kaufmann, S., Frishman, D.°: Analysis of micro-rearrangements in 25 eukaryotic species pairs by
SyntenyMapper. PLoS ONE 9:e112341 (2014)
Küffner, R.#°, Zach, N.#°, Norel, R., Hawe, J., Schoenfeld, D., Wang, L., Li, G., Fang, L., Mackey, L.,
Hardiman, O., Cudkowicz, M., Sherman, A., Ertaylan, G., Grosse-Wentrup, M., Hothorn, T., van Ligtenberg,
J., Macke, J.H., Meyer, T., Schölkopf, B., Tran, L., Vaughan, R., Stolovitzky, G., Leitner, M.L.: Crowdsourced
analysis of clinical trial data to predict amyotrophic lateral sclerosis progression. Nat. Biotechnol. 33, 51-57
(2015) [published online 2014]
Liu, X., Campillos, M.°: Unveiling new biological relationships using shared hits of chemical screening
assay pairs. Bioinformatics 30, i579-i586 (2014)
page 32 of 247
2015-11-23
#
joint first authors
#
#
Lundby, A. , Rossin, E.J. , Steffensen, A.B., Acha, M.R., Newton-Cheh, C., Pfeufer, A., Lynch, S.N.,
QT-IGC Consortium (Olsen, J.V.°), Olesen, S.P., Brunak, S., Ellinor, P.T., Jukema, J.W., Trompet, S., Ford,
I., Macfarlane, P.W., Krijthe, B.P., Hofman, A., Uitterlinden, A.G., Stricker, B.H., Nathoe, H.M., Spiering, W.,
Daly, M.J., Asselbergs, F.W., van der Harst, P., Milan, D.J., de Bakker, P.I., Lage, K.°: Annotation of loci
from genome-wide association studies using tissue-specific quantitative interaction proteomics. Nat. Methods
11, 868-874 (2014)
Mannil, D., Vogt, I., Prinz, J., Campillos, M.°: Organ system heterogeneity DB: A database for the
visualization of phenotypes at the organ system level. Nucleic Acids Res. 43, D900-D906 (2015) [published
online 2014]
Marozava, S., Röling, W.F., Seifert, J., Küffner, R., von Bergen, M., Meckenstock, R.U.°: Physiology of
Geobacter metallireducens under excess and limitation of electron donors. Part I. Batch cultivation with
excess of carbon sources. Syst. Appl. Microbiol. 37, 277-286 (2014)
Geobacter metallireducens under excess and limitation of electron donors. Part II. Mimicking environmental
conditions during cultivation in retentostats. Syst. Appl. Microbiol. 37, 287-295 (2014)
März, M.°, Beerenwinkel, N., Drosten, C., Fricke, M., Frishman, D., Hofacker, I.L., Hoffmann, D.,
Middendorf, M., Rattei, T., Stadler, P.F., Töpfer, A.: Challenges in RNA virus bioinformatics. Bioinformatics
30, 1793-1799 (2014)
Mathew, L. S., Spannagl, M., Al-Malki, A., George, B., Torres, M.F., Al-Dous, E. K., Al-Azwani, E. K.,
Hussein, E., Mathew, S., Mayer, K.F.X., Mohamoud, Y. A., Suhre, K., Malek, J. A.°: A first genetic map of
date palm (Phoenix dactylifera) reveals long-range genome structure conservation in the palms. BMC
Genomics 15:285 (2014)
Mehta, D.#, Newport, D.J.#, Frishman, G., Kraus, L., Rex-Haffner, M., Ritchie, J.C., Lori, A., Knight, B.T.,
Stagnaro, E., Ruepp, A., Stowe, Z.N., Binder, E.B.°: Early predictive biomarkers for postpartum depression
point to a role for estrogen receptor signaling. Psychol. Med. 44, 2309-2322 (2014)
#
#
Michielse, C.B. , Studt, L. , Janevska, S., Sieber, C.M.K., Arndt, B., Espino, J.J., Humpf, H.U., Güldener,
U., Tudzynski, B.°: The global regulator FfSge1 is required for expression of secondary metabolite gene
clusters, but not for pathogenicity in Fusarium fujikuroi. Environ. Microbiol. 17, 2690–2708 (2015) [published
online 2014]
Mira, N.P., Münsterkötter, M., Dias-Valada, F., Santos, J., Palma, M., Roque, F.C., Guerreiro, J.F.,
Rodrigues, F., Sousa, M.J., Leão, C., Güldener, U., Sá-Correia, I.°: The genome sequence of the highly
acetic acid-tolerant Zygosaccharomyces bailii-derived interspecies hybrid strain ISA1307, isolated from a
sparkling wine plant. DNA Res. 21, 299-313 (2014)
page 33 of 247
2015-11-23
#
joint first authors
Mook-Kanamori, D.O., Selim, M.M.E., Takiddin, A.H., Al-Homsi, H., Al-Mahmoud, K.A.S., Al-Obaidli, A.,
Zirie, M.A., Rowe, J., Yousri, N.A., Karoly, E.D., Kocher, T., Gherbi, W.S., Chidiac, O.M., Mook-Kanamori,
M.J., Kader, S.A., Al Muftah, W.A., McKeon, C., Suhre, K.°: 1,5-anhydroglucitol in saliva is a noninvasive
marker of short-term glycemic control. J. Clin. Endocrinol. Metab. 99, E479-E483 (2014)
Nasir, M.°, Rahman, S.B., Sieber, C.M.K., Mir, A., Latif, A., Ahmad, N., Malik, S.A., Hameed, A.:
Identification of recurrent c.742G>T nonsense mutation in ECM1 in Pakistani families suffering from lipoid
proteinosis. Mol. Biol. Rep. 41, 2085-2092 (2014)
#
#
Niehaus, E.M. , Janevska, S. , von Bargen, K.W., Sieber, C.M.K., Harrer, H., Humpf, H.U.°, Tudzynski, B.°:
Apicidin F: Characterization and genetic manipulation of a new secondary metabolite gene cluster in the rice
pathogen Fusarium fujikuroi. PLoS ONE 9:e103336 (2014)
Rafii, A.°, Touboul, C., Al Thani, H., Suhre, K., Malek, J.A.: Where cancer genomics should go next: A
clinician's perspective. Hum. Mol. Genet. 23, R69-R75 (2014)
Schramm, K.#, Marzi, C.#, Schurmann, C.#, Carstensen, M.#, Reinmaa, E., Biffar, R., Eckstein, G.N.,
Severin, F., Borry, P., Cornel, M.C., Daniels, N., Fellmann, F., Hodgson, S.V., Howard, H.C., John, J.,
Kääriäinen, H., Kayserili, H., Kent, A., Koerber, F., Kristoffersson, U., Kroese, M., Lewis, C.M., Marckmann,
G., Meyer, P., Pfeufer, A., Schmidtke, J., Skirton, H., Tranebjærg, L., Rogowski, W.H.°, EuroGentest
Consortium, ESHG/PPPC Priority Consortium: Points to consider for prioritizing clinical genetic testing
services: European consensus process oriented at accountability for reasonableness. Eur. J. Hum. Genet.
23, 729-735 (2014)
page 34 of 247
2015-11-23
#
joint first authors
#
#
Shin, S.-Y. , Petersen, A.-K. , Wahl, S., Zhai, G., Römisch-Margl, W., Small, K.S., Döring, A., Kato, B.S.,
(2014)
Shin, S.Y.#, Fauman, E.B.#, Petersen, A.-K.#, Krumsiek, J.#, Santos, R., Huang, J., Arnold, M., Erte, I.,
Forgetta, V., Yang, T.P., Walter, K., Menni, C., Chen, L., Vasquez, L., Valdes, A.M., Hyde, C.L., Wang, V.,
Ziemek, D., Roberts, P., Xi, L., Grundberg, E., Waldenberger, M., Richards, J.B., Mohney, R.P., Milburn,
M.V., John, S.L., Trimmer, J., Theis, F.J., Overington, J.P., Suhre, K., Brosnan, M.J., Gieger, C.,
Kastenmüller, G.°, Spector, T.D.°, Soranzo, N.°: An atlas of genetic influences on human blood metabolites.
Nat. Genet. 46, 543-550 (2014)
#
#
Sieber, C.M.K. , Lee, W. , Wong, P., Münsterkötter, M., Mewes, H.-W., Schmeitzl, C., Varga, E., Berthiller,
F., Adam, G., Güldener, U.°: The Fusarium graminearum genome reveals more secondary metabolite gene
clusters and hints of horizontal gene transfer. PLoS ONE 9:e110311 (2014)
Suhre, K.°: Metabolic profiling in diabetes. J. Endocrinol. 221, R75-R85 (2014)
Vinnikov, I.A.°, Hajdukiewicz, K., Reymann, J., Beneke, J., Czajkowski, R., Roth, L.C., Novak, M., Roller, A.,
Dörner, N., Starkuviene, V., Theis, F.J., Erfle, H., Schütz, G., Grinevich, V.°, Konopka, W.°: Hypothalamic
miR-103 protects from hyperphagic obesity in mice. J. Neurosci. 34, 10659-10674 (2014)
Vogt, I., Prinz, J., Campillos, M.°: Molecularly and clinically related drugs and diseases are enriched in
phenotypically similar drug-disease pairs. Genome Med. 6:52 (2014)
#
#
Vogt, I. , Prinz, J. , Worf, K., Campillos, M.°: Systematic analysis of gene properties influencing organ
system phenotypes in mammalian perturbations. Bioinformatics 30, 3093-3100 (2014)
Wahl, S.°, Fenske, N., Zeilinger, S., Suhre, K., Gieger, C., Waldenberger, M., Grallert, H., Schmid, M.: On
the potential of models for location and scale for genome-wide DNA methylation data. BMC Bioinformatics
15:232 (2014)
Witting, M.°, Lucio, M., Tziotis, D., Wägele, B., Suhre, K., Voulhoux, R., Garvis, S., Schmitt-Kopplin, P.:
DI-ICR-FT-MS-based high-throughput deep metabotyping: A case study of the Caenorhabditis
elegans-Pseudomonas aeruginosa infection model. Anal. Bioanal. Chem. 407, 1059-1073 (2015) [published
online 2014]
Yang, D.#, Lutter, D.#, Burtscher, I., Uetzmann, L., Theis, F.J.°, Lickert, H.°: miR-335 promotes
Development 141, 514-525 (2014)
page 35 of 247
2015-11-23
#
joint first authors
Institute of Biological and Medical Imaging
Aguirre, J.°, Schwarz, M., Soliman, D., Bühler, A., Omar, M., Ntziachristos, V.: Broadband mesoscopic
optoacoustic tomography 2 reveals skin layers. Opt. Lett. 39, 6297-6300 (2014)
Arking, D.E.#, Pulit, S.L.#, Crotti, L., van der Harst, P., Munroe, P.B., Koopmann, T.T., Sotoodehnia, N.,
page 36 of 247
2015-11-23
#
joint first authors
Bay, E., Dean-Ben, X.L., Pang, G.A., Douplik, A., Razansky, D.°: Real-time monitoring of incision profile
during laser surgery using shock wave detection. J. Biophotonics 8, 102-111 (2015) [published online 2014]
Bay, E., Dean-Ben, X.L., Pang, G.A., Douplik, A.Y., Razansky, D.°: Three-dimensional tracking of lesion
profile during laser surgery based on shock wave detection. Proc. SPIE 8943:89431N (2014)
Bayer, C., Liebhardt, M.E., Schmid, T.E., Trajkovic-Arsic, M., Hube, K., Specht, H.M., Schilling, D.,
Gehrmann, M., Stangl, S., Siveke, J.T., Wilkens, J.J., Multhoff, G.°: Validation of heat shock protein 70 as a
tumor-specific biomarker for monitoring the outcome of radiation therapy in tumor mouse models. Int. J.
Radiat. Oncol. Biol. Phys. 88, 694-700 (2014)
Bézière, N., Lozano, N., Nunes, A., Salichs, J., Queirós, D., Kostarelos, K.°, Ntziachristos, V.°: Dynamic
imaging of PEGylated Indocyanine Green (ICG) liposomes within the tumor microenvironment using
Multi-Spectral Optoacoustic Tomography (MSOT). Biomaterials 37, 415-424 (2014)
Bézière, N.°, von Schacky, C., Kosanke, Y., Kimm, M., Nunes, A., Licha, K., Aichler, M., Walch, A.K.,
Rummeny, E.J., Ntziachristos, V., Meier, R.: Optoacoustic imaging and staging of arthritic inflammation.
Arthritis Rheum. 66, 2071-2078 (2014)
Choi, S.°, Mandelis, A., Guo, X., Lashkari, B., Kellnberger, S., Ntziachristos, V.: Wavelength-Modulated
Differential Photoacoustic Spectroscopy (WM-DPAS): Theory of a high-sensitivity methodology for the
detection of early-stage tumors in tissues. Int. J. Thermophys. 36, 1305-1311 (2015) [published online 2014]
Dean-Ben, X.L., Razansky, D.°: Adding fifth dimension to optoacoustic imaging: Volumetric time-resolved
spectrally enriched tomography. Light Sci. Appl. 3:e137 (2014)
Dean-Ben, X.L., Ntziachristos, V., Razansky, D.°: Effects of small variations of speed of sound in
optoacoustic tomographic imaging. Med. Phys. 41:073301 (2014)
Dean-Ben, X.L., Bühler, A., Razansky, D., Ntziachristos, V.°: Estimation of optoacoustic contrast agent
concentration with self-calibration blind logarithmic unmixing. Phys. Med. Biol. 59, 4785-4797 (2014)
Dean-Ben, X.L., Deliolanis, N.C., Ntziachristos, V., Razansky, D.°: Fast unmixing of multispectral
optoacoustic data with vertex component analysis. Opt. Laser Eng. 58, 119-125 (2014)
Dean-Ben, X.L., Bay, E., Razansky, D.°: Functional optoacoustic imaging of moving objects using
microsecond-delay acquisition of multispectral three-dimensional tomographic data. Sci. Rep. 4:5878 (2014)
Dean-Ben, X.L., Fehm, T., Razansky, D.°: Universal hand-held three-dimensional optoacoustic imaging
probe for deep tissue human angiography and functional preclinical studies in real time. J. Vis. Exp.
93:e51864 (2014)
Deliolanis, N.C.°, Ale, A., Morscher, S., Burton, N.C., Schaefer, K., Radrich, K., Razansky, D.,
Ntziachristos, V.: Deep-tissue reporter-gene imaging with fluorescence and optoacoustic tomography: A
performance overview. Mol. Imaging Biol. 16, 652-660 (2014)
page 37 of 247
2015-11-23
#
joint first authors
Dima, A., Burton, N.C., Ntziachristos, V.°: Multispectral optoacoustic tomography at 64, 128, and 256
channels. J. Biomed. Opt. 19:36021 (2014)
Dobosz, M.°, Ntziachristos, V., Scheuer, W., Strobel, S.: Multispectral fluorescence ultramicroscopy:
Three-dimensional visualization and automatic quantification of tumor morphology, drug penetration, and
antiangiogenic treatment response. Neoplasia 16, 1-13 (2014)
Ermolayev, V., Mohajerani, P., Ale, A., Sarantopoulos, A., Aichler, M., Kayser, G., Walch, A.K.,
Ntziachristos, V.°: Early recognition of lung cancer by integrin targeted imaging in K-ras mouse model. Int.
J. Cancer 137, 1107-1118 (2015) [published online 2014]
Estrada, H., Soboll, S., Baum, O., Razansky, D.°: Hybrid optoacoustic and ultrasound biomicroscopy
monitors' laser-induced tissue modifications and magnetite nanoparticle impregnation. Laser Phys. Lett.
11:125601 (2014)
Estrada, H., Turner, J.E., Kneipp, M., Razansky, D.°: Real-time optoacoustic brain microscopy with hybrid
optical and acoustic resolution. Laser Phys. Lett. 11:045601 (2014)
Fehm, T., Dean-Ben, X.L., Razansky, D.°: Four dimensional hybrid ultrasound and optoacoustic imaging
via passive element optical excitation in a hand-held probe. Appl. Phys. Lett. 105:173505 (2014)
Gaipl, U.S.°, Multhoff, G., Scheithauer, H.R., Lauber, K., Hehlgans, S., Frey, B.R., Rödel, F.: Kill and
spread the word: Stimulation of antitumor immune responses in the context of radiotherapy. Immunotherapy
6, 597-610 (2014)
Garcia-Allende, P.°, Glatz, J., Koch, M., Tjalma, J.J., Hartmans, E., Terwisscha van Scheltinga, A.G.,
Symvoulidis, P., van Dam, G.M., Nagengast, W.B., Ntziachristos, V.: Towards clinically translatable NIR
fluorescence molecular guidance for colonoscopy. Biomed. Opt. Express 5, 78-92 (2014)
Gehrmann, M., Cervello, M., Montalto, G., Cappello, F., Gulino, A., Knape, C., Specht, H.M., Multhoff, G.°:
Heat shock protein 70 serum levels differ significantly in patients with chronic hepatitis, liver cirrhosis, and
hepatocellular carcinoma. Front. Immunol. 5:307 (2014)
Gehrmann, M., Specht, H.M., Bayer, C., Brandstetter, M., Chizzali, B., Duma, M., Breuninger, S., Hube, K.,
Lehnerer, S., van Phi, V., Sage, E.H., Schmid, T.E., Sedelmayr, M., Schilling, D., Sievert, W., Stangl, S.,
Multhoff, G.°: Hsp70 - a biomarker for tumor detection and monitoring of outcome of radiation therapy in
patients with squamous cell carcinoma of the head and neck. Radiat. Oncol. 9:131 (2014)
Gehrmann, M., Stangl, S., Foulds, G.A., Oellinger, R., Breuninger, S., Rad, R., Pockley, A.G., Multhoff, G.°:
Tumor imaging and targeting potential of an Hsp70-derived 14-Mer peptide. PLoS ONE 9:e105344 (2014)
Glatz, J., Symvoulidis, P., Garcia-Allende, P., Ntziachristos, V.°: Robust overlay schemes for the fusion of
fluorescence and color channels in biological imaging. J. Biomed. Opt. 19:40501 (2014)
page 38 of 247
2015-11-23
#
joint first authors
Ho, C.J., Balasundaram, G., Driessen, W.H.P., McLaren, R., Wong, C.L., Dinish, U.S., Attia, A.B.,
Ntziachristos, V., Olivo, M.°: Multifunctional photosensitizer-based contrast agents for photoacoustic
imaging. Sci. Rep. 4:5342 (2014)
Jin, A.°, Yazici, B.°, Ntziachristos, V.°: Light illumination and detection patterns for fluorescence diffuse
optical tomography based on compressive sensing. IEEE Trans. Image Process. 23, 2609-2624 (2014)
#
#
Kang, N.Y. , Park, S.J. , Ang, X.W., Samanta, A., Driessen, W.H.P., Ntziachristos, V., Vasquez, K.O.,
Peterson, J.D., Yun, S.W.°, Chang, Y.T.: A macrophage uptaking near-infrared chemical probe for in vivo
imaging of inflammation. Chem. Commun. 50, 6589-6591 (2014)
Karopka, T.°, Schmuhl, H.-H., Demski, H.: Free/libre open source software in health care: A review.
Healthc. Inform. Res. 20, 11-22 (2014)
#
#
#
Kneipp, M. , Turner, J.E. , Hambauer, S. , Krieg, S.M., Lehmberg, J., Lindauer, U., Razansky, D.°:
Functional real-time optoacoustic imaging of middle cerebral artery occlusion in mice. PLoS ONE 9:e96118
(2014)
Koch, M., Glatz, J., Ermolayev, V., de Vries, E.G., van Dam, G.M., Englmeier, K.-H., Ntziachristos, V.°:
Video-rate optical flow corrected intraoperative functional fluorescence imaging. J. Biomed. Opt. 19:46012
(2014)
Lozano, N., Al-Ahmady, Z.S., Bézière, N., Ntziachristos, V.°, Kostarelos, K.°: Monoclonal antibody-targeted
PEGylated liposome-ICG encapsulating doxorubicin as a potential theranostic agent. Int. J. Pharm. 482, 2-10
Lutzweiler, C., Dean-Ben, X.L., Razansky, D.°: Expediting model-based optoacoustic reconstructions with
tomographic symmetries. Med. Phys. 41:013302 (2014)
Lutzweiler, C.°, Meier, R., Rummeny, E., Ntziachristos, V., Razansky, D.°: Real-time optoacoustic
tomography of indocyanine green perfusion in human vasculature. Opt. Lett. 39, 4061-4064 (2014)
Mandal, S.#, Nasonova, E.#, Dean-Ben, X.L., Razansky, D.°: Optimal self-calibration of tomographic
reconstruction parameters in whole-body small animal optoacoustic imaging. Photoacoustics 2, 128-136
(2014)
Mohajerani, P., Kellnberger, S., Ntziachristos, V.°: Fast Fourier backprojection for frequency-domain
optoacoustic tomography. Opt. Lett. 39, 5455-5458 (2014)
Mohajerani, P., Koch, M., Thürmel, K., Haller, B., Rummeny, E.J., Ntziachristos, V., Meier, R.°:
Fluorescence-aided tomographic imaging of synovitis in the human finger. Radiology 272, 865-874 (2014)
Mohajerani, P., Hipp, A., Willner, M., Marschner, M., Trajkovic-Arsic, M., Ma, X., Burton, N.C., Klemm, U,,
Radrich, K., Ermolayev, V., Tzoumas, S., Siveke, J., Bech, M., Pfeiffer, F., Ntziachristos, V.°: FMT-PCCT:
Hybrid fluorescence molecular tomography-X-ray phase-contrast CT imaging of mouse models. IEEE Trans.
Med. Imaging 33, 1434-1446 (2014)
page 39 of 247
2015-11-23
#
joint first authors
Mohajerani, P., Kellnberger, S., Ntziachristos, V.°: Frequency domain optoacoustic tomography using
amplitude and phase. Photoacoustics 2, 111-118 (2014)
Multhoff, G.°, Radons, J.R., Vaupel, P.W.: Critical role of aberrant angiogenesis in the development of
tumor hypoxia and associated radioresistance. Cancers 6, 813-823 (2014)
Ntziachristos, V.°: Optoacoustics as a bioengineering model for neuroscience discovery. Adv. Exp. Med.
Biol. 820, DOI: 10.1007/978-3-319-09012-2_1 (2015)
Omar, M.°, Gateau, J., Ntziachristos, V.: High-resolution raster scan optoacoustic mesoscopy of genetically
modified drosophila pupae. Proc. SPIE 8943:89431F (2014)
Omar, M., Soliman, D., Gateau, J., Ntziachristos, V.°: Ultrawideband reflection-mode optoacoustic
mesoscopy. Opt. Lett. 39, 3911-3914 (2014)
Pang, G.A., Bay, E., Dean-Ben, X.L., Razansky, D.°: Three-dimensional optoacoustic monitoring of lesion
formation in real time during radiofrequency catheter ablation. J. Cardiovasc. Electrophysiol. 26, 339-345
Peter, L., Mateus, D., Chatelain, P., Schworm, N., Stangl, S., Multhoff, G., Navab, N.: Leveraging random
forests for interactive exploration of large histological images. Lecture Notes Comp. Sci. 8673, 1-8 (2015)
Pleijhuis, R.G., Timmermans, A., de Jong, J.S., de Boer, E., Ntziachristos, V., van Dam, G.M.°:
Tissue-simulating phantoms for assessing potential near-infrared fluorescence imaging applications in breast
cancer surgery. J. Vis. Exp. 91:e51776 (2014)
Pockley, A.G.°, Henderson, B., Multhoff, G.: Extracellular cell stress proteins as biomarkers of human
disease. Biochem. Soc. Trans. 42, 1744-1751 (2014)
Press, A.T.#, Traeger, A.#, Pietsch, C., Mosig, A., Wagner, M., Clemens, M.G., Jbeily, N., Koch, N.,
Gottschaldt, M., Bézière, N., Ermolayev, V., Ntziachristos, V., Popp, J., Kessels, M.M., Qualmann, B.,
Schubert, U.S., Bauer, M.°: Cell type-specific delivery of short interfering RNAs by dye-functionalised
theranostic nanoparticles. Nat. Commun. 5:5565 (2014)
Radrich, K., Mohajerani, P., Bussemer, J., Schwaiger, M., Beer, A.J., Ntziachristos, V.°:
Limited-projection-angle hybrid fluorescence molecular tomography of multiple molecules. J. Biomed. Opt.
19:46016 (2014)
Rosenthal, A.°, Ntziachristos, V., Razansky, D.: Acoustic inversion in optoacoustic tomography: A review.
Curr. Med. Imaging Rev. 9, 318-336 (2013)
Rosenthal, A.°, Omar, M., Estrada, H., Kellnberger, S., Razansky, D., Ntziachristos, V.: Embedded
ultrasound sensor in a silicon-on-insulator photonic platform. Appl. Phys. Lett. 104:021116 (2014)
page 40 of 247
2015-11-23
#
joint first authors
Rosenthal, A.°, Kellnberger, S., Bozhko, D., Chekkoury, A., Omar, M., Razansky, D., Ntziachristos, V.:
Sensitive interferometric detection of ultrasound for minimally invasive clinical imaging applications. Laser
Photon. Rev. 8, 450-457 (2014)
Rosenthal, A., Kellnberger, S., Omar, M., Razansky, D., Ntziachristos, V.: Wideband optical detector of
ultrasound for medical imaging applications. J. Vis. Exp. 87:e50847 (2014)
Schilling, D., Tetzlaff, F., Konrad, S., Li, W., Multhoff, G.°: A hypoxia-induced decrease of either MICA/B or
Hsp70 on the membrane of tumor cells mediates immune escape from NK cells. Cell Stress Chaperones 20,
139-147 (2014)
Schwarz, M., Omar, M., Bühler, A., Aguirre, J., Ntziachristos, V.°: Implications of ultrasound frequency in
optoacoustic mesoscopy of the skin. IEEE Trans. Med. Imaging 34, 672-677 (2015) [published online 2014]
Schwarz, M., Bühler, A., Ntziachristos, V.°: Isotropic high resolution optoacoustic imaging with linear
detector arrays in bi-directional scanning. J. Biophotonics 8, 60-70 (2015) [published online 2014]
Seemann, K.M.°, Luysberg, M., Revay, Z., Kudejova, P., Sague, B.S., Cassinelli, N., Loidl, A., Ilicic, K.,
Multhoff, G., Schmid, T.E.: Magnetic heating properties and neutron activation of tungsten-oxide coated
biocompatible FePt core-shell nanoparticles. J. Control. Release 197, 131-137 (2014)
Sievert, W., Tapio, S., Breuninger, S., Gaipl, U., Andratschke, N., Trott, K.R., Multhoff, G.°: Adhesion
molecule expression and function of primary endothelial cells in benign and malignant tissues correlates with
proliferation. PLoS ONE 9:e91808 (2014)
Stangl, S., Varga, J., Freysoldt, B., Trajkovic-Arsic, M., Siveke, J.T., Greten, F.R., Ntziachristos, V.,
Multhoff, G.°: Selective in vivo imaging of tumors with a tumor cell-specific Hsp70 peptide-based probe.
Cancer Res. 74, 6903-6912 (2014)
Stranic, I.°, Pang, G.A., Hanson, R.K., Golden, D.M., Bowman, C.T.: Shock tube measurements of the rate
constant for the reaction ethanol + OH. J. Phys. Chem. A 118, 822-828 (2014)
Symvoulidis, P., Jentoft, K., Garcia-Allende, P., Glatz, J., Ripoll, J., Ntziachristos, V.°: Steady-state total
diffuse reflectance with an exponential decaying source. Opt. Lett. 39, 3919-3922 (2014)
Taruttis, A., Rosenthal, A., Kacprowicz, M., Burton, N.C., Ntziachristos, V.°: Multiscale multispectral
optoacoustic tomography by a stationary wavelet transform prior to unmixing. IEEE Trans. Med. Imaging 33,
1194-1202 (2014)
Taruttis, A., Lozano, N., Nunes, A., Jasim, D.A., Bézière, N., Herzog, E., Kostarelos, K.°, Ntziachristos,
V.°: siRNA liposome-gold nanorod vectors for multispectral optoacoustic tomography theranostics.
Nanoscale 6, 13451-13456 (2014)
page 41 of 247
2015-11-23
#
joint first authors
Trajkovic-Arsic, M., Mohajerani, P., Sarantopoulos, A., Kalideris, E., Steiger, K., Esposito, I., Ma, X.,
Themelis, G., Burton, N.C., Michalski, C.W., Kleeff, J., Stangl, S., Beer, A.J., Pohle, K., Wester, H.J.,
Schmid, R.M., Braren, R., Ntziachristos, V., Siveke, J.T.°: Multimodal molecular imaging of integrin αvβ3 for
in vivo detection of pancreatic cancer. J. Nucl. Med. 55, 446-451 (2014)
Tserevelakis, G.J., Soliman, D., Omar, M., Ntziachristos, V.°: Hybrid multiphoton and optoacoustic
microscope. Opt. Lett. 39, 1819-1822 (2014)
Turner, J.E., Estrada, H., Kneipp, M., Razansky, D.°: Improved optoacoustic microscopy through
three-dimensional spatial impulse response synthetic aperture focusing technique. Opt. Lett. 39, 3390-3393
(2014)
Tzoumas, S., Nunes, A., Deliolanis, N.C., Ntziachristos, V.°: Effects of multispectral excitation on the
sensitivity of molecular optoacoustic imaging. J. Biophotonics 8, 629–637 (2015) [published online 2014]
#
#
Tzoumas, S. °, Zaremba, A. , Klemm, U., Nunes, A., Schaefer, K., Ntziachristos, V.: Immune cell
imaging using multi-spectral optoacoustic tomography. Opt. Lett. 39, 3523-3526 (2014)
Tzoumas, S.°, Rosenthal, A., Lutzweiler, C., Razansky, D., Ntziachristos, V.: Spatiospectral denoising
framework for multispectral optoacoustic imaging based on sparse signal representation. Med. Phys.
41:113301 (2014)
Veres, I.A.°, Burgholzer, P., Berer, T., Rosenthal, A., Wissmeyer, G., Ntziachristos, V.: Characterization of
the spatio-temporal response of optical fiber sensors to incident spherical waves. J. Acoust. Soc. Am. 135,
1853-1862 (2014)
Vonnemann, J.°, Bézière, N.°, Böttcher, C., Riese, S.B., Kuehne, C., Dernedde, J., Licha, K., von Schacky,
C., Kosanke, Y., Kimm, M., Meier, R., Ntziachristos, V., Haag, R.: Polyglycerolsulfate functionalized gold
nanorods as optoacoustic signal nanoamplifiers for in vivo bioimaging of rheumatoid arthritis. Theranostics 4,
629-641 (2014)
page 42 of 247
2015-11-23
#
joint first authors
Institute of Clinical Molecular Biology and Tumor Genetics
Alachkar, H., Mutonga, M.B., Metzeler, K.H., Fulton, N., Malnassy, G., Herold, T., Spiekermann, K.,
Bohlander, S.K., Hiddemann, W., Matsuo, Y., Stock, W., Nakamura, Y.°: Preclinical efficacy of Maternal
Embryonic Leucine-zipper Kinase (MELK) inhibition in acute myeloid leukemia. Oncotarget 5, 12371-12382
(2014)
Boldt, K.°, Gloeckner, C.J., Texier, Y., von Zweydorf, F., Ueffing, M.°: Applying SILAC for the differential
analysis of protein complexes. Methods Mol. Biol. 1188, 177-190 (2014)
Bösken, C.A., Farnung, L., Hintermair, C., Merzel Schachter, M., Vogel-Bachmayr, K., Blazek, D., Anand,
K., Fisher, R.P., Eick, D., Geyer, M.°: The structure and substrate specificity of human Cdk12/Cyclin K. Nat.
Commun. 5:3505 (2014)
Coordes, B., Brünger, K.M., Burger, K., Soufi, B., Horenk, J., Eick, D., Olsen, J.V., Sträßer, K.°: Ctk1
function is necessary for full translation initiation activity in Saccharomyces cerevisiae. Eukaryot. Cell 14,
Davari, K., Frankenberger, S., Schmidt, A., Tomi, N.S., Jungnickel, B.°: Checkpoint kinase 2 is required for
efficient immunoglobulin diversification. Cell Cycle 13, 3659-3669 (2014)
Descostes, N.#, Heidemann, M.#, Spinelli, L., Schüller, R., Maqbool, M.A., Fenouil, R., Koch, F., Innocenti,
C., Gut, M., Gut, I., Eick, D.°, Andrau, J.C.°: Tyrosine phosphorylation of RNA polymerase II CTD is
associated with antisense promoter transcription and active enhancers in mammalian cells. eLife 3:e02105
(2014)
#
#
Frankenberger, S. , Davari, K. , Fischer-Burkart, S., Böttcher, K., Tomi, N.S., Zimber-Strobl, U.,
Jungnickel, B.°: Checkpoint kinase 1 negatively regulates somatic hypermutation. Nucleic Acids Res. 42,
3666-3674 (2014)
Friedmann Angeli, J.P., Schneider, M., Proneth, B., Tyurina, Y.Y., Tyurin, V.A., Hammond, V.J., Herbach,
N., Aichler, M., Walch, A.K., Eggenhofer, E., Basavarajappa, D., Rådmark, O., Kobayashi, S., Seibt, T.,
Beck, H., Neff, F., Esposito, I., Wanke, R., Förster, H., Yefremova, O., Heinrichmeyer, M., Bornkamm,
G.W., Geissler, E.K., Thomas, S.B., Stockwell, B.R., O'Donnell, V.B., Kagan, V.E., Schick, J.°, Conrad, M.°:
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat. Cell Biol. 16,
1180-1191 (2014)
Heinrich, D.A.°, Weinkauf, M., Hutter, G., Zimmermann, Y., Jurinovic, V., Hiddemann, W., Dreyling, M.:
Differential regulation patterns of the anti-CD20 antibodies obinutuzumab and rituximab in mantle cell
lymphoma. Br. J. Haematol. 168, 606-610 (2015) [published online 2014]
Herold, T., Metzeler, K.H., Vosberg, S., Hartmann, L., Röllig, C., Stölzel, F., Schneider, S., Hubmann, M.,
Zellmeier, E., Ksienzyk, B., Jurinovic, V., Pasalic, Z., Kakadia, P.M., Dufour, A., Graf, A., Krebs, S., Blum, H.,
Sauerland, M.C., Büchner, T., Berdel, W.E., Woermann, B.J., Bornhäuser, M., Ehninger, G., Mansmann, U.,
Hiddemann, W., Bohlander, S.K., Spiekermann, K., Greif, P.A.°: Isolated trisomy 13 defines a genetically
homogenous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis.
Blood 124, 1304-1311 (2014)
page 43 of 247
2015-11-23
#
joint first authors
Hubmann, M.°, Köhnke, T., Hoster, E., Schneider, S., Dufour, A., Zellmeier, E., Fiegl, M., Braess, J.,
Bohlander, S.K., Subklewe, M., Sauerland, M.C., Berdel, W.E., Büchner, T., Wörmann, B., Hiddemann, W.,
Spiekermann, K.: Molecular response assessment by quantitativerael-time polymerase chain reaction after
induction therapy in NPM1-mutated patients identifies patients at high risk for relapse. Haematologica 99,
1317-1325 (2014)
Janke, H.°, Pastore, F., Schumacher, D., Herold, T., Hopfner, K.P., Schneider, S., Berdel, W.E., Büchner,
T., Woermann, B.J., Subklewe, M., Bohlander, S.K., Hiddemann, W., Spiekermann, K., Polzer, H.:
Activating FLT3 mutants show distinct gain-of-function phenotypes in vitro and a characteristic signaling
pathway profile associated with prognosis in acute myeloid leukemia. PLoS ONE 9:e89560 (2014)
Jin, S., Kim, J., Willert, T., Klein-Rodewald, T., Garcia-Dominguez, M., Mosqueira, M., Fink, R., Esposito,
I., Hofbauer, L.C., Charnay, P., Kieslinger, M.°: Ebf factors and MyoD cooperate to regulate muscle
relaxation via Atp2a1. Nat. Commun. 5:3793 (2014)
Köhnke, T., Sauter, D., Ringel, K., Hoster, E., Laubender, R.P., Hubmann, M., Bohlander, S.K., Kakadia,
P.M., Schneider, S., Dufour, A., Sauerland, M.C., Berdel, W.E., Büchner, T., Wörmann, B., Braess, J.,
Hiddemann, W., Spiekermann, K., Subklewe, M.°: Early assessment of minimal residual disease in aml by
flow cytometry during aplasia identifies patients at increased risk of relapse. Leukemia 29, 377-386 (2015)
Lehmann, F.M.°, Maurberger, A., Feicht, S., Helm, F., Ladinig, C., Kieback, E., Uckert, W., Kammertöns, T.,
Kremmer, E., Mautner, J., Gerbitz, A., Bornkamm, G.W.°: Targeting high-grade B cell lymphoma with
CD19-specific T cells. Int. J. Cancer 135, 1153-1164 (2014)
Lichtenegger, F.S., Lorenz, R., Gellhaus, K., Hiddemann, W., Beck, B., Subklewe, M.°: Impaired NK cells
and increased T regulatory cell numbers during cytotoxic maintenance therapy in AML. Leuk. Res. 38,
964-969 (2014)
Lichtenegger, F.S.°, Schnorfeil, F.M., Emmerig, K., Schlueter, M., Neitz, J.S., Draenert, R., Hiddemann,
W., Subklewe, M.: Pseudo-exhaustion of T cells in relapsed AML. Haematologica 99, 288-289 (2014)
Linnerbauer, S., Behrends, U., Adhikary, D., Witter, K., Bornkamm, G.W., Mautner, J.°: Virus and
autoantigen-specific CD4+ T cells are key effectors in a SCID mouse model of EBV-associated
post-transplant lymphoproliferative disorders. PLoS Pathog. 10:e1004068 (2014)
Neumann, M., Seehawer, M., Schlee, C., Vosberg, S., Heesch, S., von der Heide, E.K., Graf, A., Krebs, S.,
Blum, H., Gökbuget, N., Schwartz, S., Hoelzer, D., Greif, P.A., Baldus, C.D.°: FAT1 expression and
mutations in adult acute lymphoblastic leukemia. Blood Cancer J. 4:e224 (2014)
page 44 of 247
2015-11-23
#
joint first authors
Pastore, F.°, Dufour, A., Benthaus, T., Metzeler, K.H., Maharry, K.S., Schneider, S., Ksienzyk, B., Mellert,
G., Zellmeier, E., Kakadia, P.M., Unterhalt, M., Feuring-Buske, M., Buske, C., Braess, J., Sauerland, M.C.,
Heinecke, A., Krug, U., Berdel, W.E., Buechner, T., Woermann, B.J., Hiddemann, W., Bohlander, S.K.,
Marcucci, G., Spiekermann, K., Bloomfield, C.D., Hoster, E.: Combined molecular and clinical prognostic
index for relapse and survival in cytogenetically normal acute myeloid leukemia. J. Clin. Oncol. 32,
1586-1594 (2014)
Pastore, F.°, Greif, P.A., Schneider, S., Ksienzyk, B., Mellert, G., Zellmeier, E., Braess, J., Sauerland, C.M.,
Heinecke, A., Krug, U., Berdel, W.E., Buechner, T., Woermann, B.J., Hiddemann, W., Spiekermann, K.:
The NPM1 mutation type has no impact on survival in cytogenetically normal AML. PLoS ONE 9:e109759
(2014)
Peng, X., Mandal, P.K., Kaminskyy, V.O., Lindqvist, A., Conrad, M., Arner, E.S.J.°: Sec-containing TrxR1 is
essential for self-sufficiency of cells by control of glucose-derived H2O2. Cell Death Dis. 5:e1235 (2014)
Rachner, T.D.°, Thiele, S., Goebel, A., Browne, A., Fuessel, S., Erdmann, K., Wirth, M.P., Froehner, M.,
Todenhoefer, T., Muders, M.H., Kieslinger, M., Rauner, M., Hofbauer, L.C.: High serum levels of Dickkopf-1
are associated with a poor prognosis in prostate cancer patients. BMC Cancer 14:649 (2014)
Sandhöfer, N., Metzeler, K.H., Carlet, M., Dufour, A., Fröhling, S., Groiß, V., Grunert, M., Herold, T.,
Hinrichsen, T., Hiddemann, W., Klein, H.G., Rothenburg, M., Schneider, S., Subklewe, M., Tiedt, S.,
Wachter, O., Walter, G., Jeremias, I., Spiekermann, K.°: Dual PI3K/mTOR inhibition shows antileukemic
activity in MLL rearranged acute myeloid leukemia. Leukemia 29, 828-838 (2015) [published online 2014]
Stadler, C.R.#, Vegi, N.#, Mulaw, M.A., Edmaier, K.E., Rawat, V.P.S., Dolnik, A., Bullinger, L., Heilmeier, B.,
Quintanilla-Fend, L., Spiekermann, K., Hiddemann, W., Döhner, K., Döhner, H., Feuring-Buske, M., Buske,
C.°: The leukemogenicity of Hoxa9 depends on alternative splicing. Leukemia 28, 1838-1843 (2014)
Tomi, N.S., Davari, K., Grotzky, D., Loos, F., Böttcher, K., Frankenberger, S., Jungnickel, B.°: Analysis of
SHPRH functions in DNA repair and immunoglobulin diversification. DNA Repair 24, 63-72 (2014)
Yoda, A., Adelmant, G., Tamburini, J., Chapuy, B., Shindoh, N., Yoda, Y., Weigert, O., Kopp, N., Wu, S.C.,
Kim, S.S., Liu, H., Tivey, T., Christie, A.L., Elpek, K.G., Card, J., Gritsman, K., Gotlib, J., Deininger, M.W.,
Makishima, H., Turley, S.J., Javidi-Sharifi, N., Maciejewski, J.P., Jaiswal, S., Ebert, B.L., Rodig, S.J., Tyner,
J.W., Marto, J.A., Weinstock, D.M.°, Lane, A.A.°: Mutations in G protein β subunits promote transformation
and kinase inhibitor resistance. Nat. Med. 21, 71-75 (2015) [published online 2014]
page 45 of 247
2015-11-23
#
joint first authors
Institute of Computational Biology
Aichler, M., Motschmann, M., Jütting, U., Luber, B., Becker, K., Ott, K., Lordick, F., Langer, R., Feith, M.,
Siewert, J.R., Walch, A.K.°: Epidermal Growth Factor Receptor (EGFR) is an independent adverse
prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant
chemotherapy. Oncotarget 5, 6620-6632 (2014)
Alfonso, J.C.L., Jagiella, N., Nuñez, L., Herrero, M.A.°, Drasdo, D.: Estimating dose painting effects in
radiotherapy: A mathematical model. PLoS ONE 9:e89380 (2014)
Altschuh, J.°, Lenoir, D., Rehfeldt, F., Brüggemann, R.: Applicability domain of nonlinear property-property
relationships - example: Estimation of vapour pressure. Match-Commun. Math. Comput. Chem. 73, 303-326
(2015)
Bajikar, S.S.#, Fuchs, C.#, Roller, A., Theis, F.J.°, Janes, K.A.°: Parameterizing cell-to-cell regulatory
heterogeneities via stochastic transcriptional profiles. Proc. Natl. Acad. Sci. U.S.A. 111, E626-E635 (2014)
Bergmann, R.°, Weinmann, A.°: Inpainting of cycling data using first and second order differences. Lecture
Notes Comp. Sci. 8932, 155-168 (2015)
Brüggemann, R.°, Scherb, H., Schramm, K.-W., Cok, I., Voigt, K.: CombiSimilarity, an innovative method to
compare environmental and health data sets with different attribute sizes example: Eighteen organochlorine
pesticides in soil and human breast milk samples. Ecotoxicol. Environ. Saf. 105, 29-35 (2014)
Buddrus-Schiemann, K., Rieger, M., Mühlbauer, M., Barbarossa, M.V., Kuttler, C., Hense, B.A.,
Rothballer, M., Uhl, J., Fonseca, J.R., Schmitt-Kopplin, P., Schmid, M., Hartmann, A.°: Analysis of
N-acylhomoserine lactone dynamics in continuous cultures of Pseudomonas putida IsoF by use of ELISA
and UHPLC/qTOF-MS-derived measurements and mathematical models. Anal. Bioanal. Chem. 406,
6373-6383 (2014)
Buettner, F.°, Moignard, V., Göttgens, B., Theis, F.J.: Probabilistic PCA of censored data: Accounting for
uncertainties in the visualisation of high-throughput single-cell qPCR data. Bioinformatics 30, 1867-1875
(2014)
Carvalho, A.N.°, Sonner, S.: Pullback exponential attractors for evolution processes in Banach spaces:
Properties and applications. Commun. Pure Appl. Anal. 13, 1141-1165 (2014)
Chui, C.K.°, Filbir, F., Mhaskar, H.N.: Representation of functions on big data: Graphs and trees. Appl.
Comput. Harmon. Anal. 38, 489-509 (2014)
Do, K.T., Kastenmüller, G., Mook-Kanamori, D.O., Yousri, N.A., Theis, F.J., Suhre, K., Krumsiek, J.°:
Network-based approach for analyzing intra- and interfluid metabolite associations in human blood, urine,
and saliva. J. Proteome Res. 14, 1183-1194 (2015) [published online 2014]
Dong, Y.°, Görner, T.°, Kunis, S.°: An algorithm for total variation regularized photoacoustic imaging. Adv.
Comput. Math. 41, 423-438 (2015) [published online 2014]
page 46 of 247
2015-11-23
#
joint first authors
Ebert, M.A.°, Gulliford, S.L., Buettner, F., Foo, K., Haworth, A., Kennedy, A., Joseph, D.J., Denham, J.W.:
Two non-parametric methods for derivation of constraints from radiotherapy dose-histogram data. Phys.
Med. Biol. 59, N101-N111 (2014)
Ehler, M.°, Filbir, F.: ξ-coverings of Hölder-Zygmund type spaces on data-defined manifolds. Abstract Appl.
Anal. 2014:402918 (2014)
Eisenhofer, S.°, Efendiyev, M.A., Otani, M., Schulz, S., Zischka, H.: On the ODE-PDE coupling model of
the mitochondrial swelling process. Discrete Contin. Dyn. Syst.-Ser. B 20, 1031-1057 (2015) [published
online 2014]
Fehringer, A., Lasser, T., Zanette, I., Noel, P.B., Pfeiffer, F.°: A versatile tomographic forward- and
back-projection approach on multi-GPUs. Proc. SPIE 9034:90344F (2014)
Feigelman, J., Theis, F.J., Marr, C.°: MCA: Multiresolution Correlation Analysis, a graphical tool for
subpopulation identification in single-cell gene expression data. BMC Bioinformatics 15:240 (2014)
Feuchtinger, A.°, Stiehler, T., Jütting, U., Marjanovic, G., Luber, B., Langer, R., Walch, A.K.: Image
analysis of immunohistochemistry is superior to visual scoring as shown for patient outcome of esophageal
adenocarcinoma. Histochem. Cell Biol. 143, 1-9 (2014)
Filbir, F.°, Kunis, S.°, Seyfried, R.°: Effective discretization of direct reconstruction schemes for
photoacoustic imaging in spherical geometries. SIAM J. Numer. Anal. 52, 2722-2742 (2014)
Fröhlich, F.°, Hross, S.°, Theis, F.J.°, Hasenauer, J.°: Radial basis function approximations of Bayesian
parameter posterior densities for uncertainty analysis. Lecture Notes Comp. Sci. 8859, 73-85 (2014)
Fröhlich, F.°, Theis, F.J.°, Hasenauer, J.°: Uncertainty analysis for non-identifiable dynamical systems:
Profile likelihoods, bootstrapping and more. Lecture Notes Comp. Sci. 8859, 61-72 (2014)
Gölgeli Matur, M.°, Müller, J., Kuttler, C., Hense, B.A.: An approximative approach for single cell spatial
modeling of quorum sensing. J. Comput. Biol. 22, 227-235 (2015) [published online 2014]
Grote, J., Krysciak, D., Schorn, A., Dahlke, R.I., Soonvald, L., Müller, J., Hense, B.A., Schwarzfischer, M.,
Sauter, M., Schmeisser, C., Streit, W.R.°: Evidence of autoinducer-dependent and autoinducer-independent
heterogeneous gene expression in Sinorhizobium fredii NGR234. Appl. Environ. Microbiol. 80, 5572-5582
(2014)
Hartmann, A., Rothballer, M., Hense, B.A., Schröder, P.: Bacterial quorum sensing compounds are
important modulators of microbe-plant interactions. Front. Plant Sci. 5:131 (2014)
page 47 of 247
2015-11-23
#
joint first authors
Hasenauer, J.°, Hasenauer, C., Hucho, T., Theis, F.J.: ODE constrained mixture modelling: A method for
unraveling subpopulation structures and dynamics. PLoS Comput. Biol. 10:e1003686 (2014)
Hennersperger, C.°, Mateus, D., Baust, M., Navab, N.A.: A quadratic energy minimization framework for
signal loss estimation from arbitrarily sampled ultrasound data. Lecture Notes Comp. Sci. 8674, 373-380
(2014)
#
#
#
Hentzschel, F. , Hammerschmidt-Kamper, C. , Börner, K. , Heiss, K., Knapp, B., Sattler, J.M., Kaderali, L.,
Castoldi, M., Bindman, J.G., Malato, Y., Willenbring, H., Mueller, A.K.°, Grimm, D.°: AAV8-mediated in vivo
overexpression of miR-155 enhances the protective capacity of genetically-attenuated malarial parasites.
Mol. Ther. 22, 2130-2141 (2014)
Illner, K., Fuchs, C., Theis, F.J.°: Bayesian blind source separation for data with network structure. J.
Comput. Biol. 21, 855-865 (2014)
Kämmerer, L.°, Kunis, S.°, Melzer, I.°, Potts, D.°, Volkmer, T.°: Computational methods for the Fourier
analysis of sparse high-dimensional functions. Lecture Notes Comp. Sci. Eng. 102, 347-363 (2014)
Khakhutskyy, V.°, Schwarzfischer, M.°, Hubig, N.°, Plant, C.°, Marr, C.°, Rieger, M.A.°, Schröder, T.°,
Theis, F.J.°: Centroid clustering of cellular lineage trees. Lecture Notes Comp. Sci. 8649, 15-29 (2014)
Landsberger, P., Boenke, V., Gorbushina, A.A., Rodenacker, K., Pierce, B.F., Kratz, K., Lendlein, A.°:
Bacterial attachment on poly[acrylonitrile-co-(2-methyl-2-propene-1- sulfonic acid)] surfaces. Mat. Res. Soc.
Symp. Proc. 1569, 85-90 (2013)
Löhning, M.°, Reble, M.°, Hasenauer, J.°, Yu, S.°, Allgöwer, F.°: Model predictive control using reduced
order models: Guaranteed stability for constrained linear systems. J. Process Contr. 24, 1647-1659 (2014)
Lukowiak, M.C., Wettmarshausen, S., Hidde, G., Landsberger, P., Boenke, V., Rodenacker, K., Braun, U.,
Friedrich, J.F., Gorbushina, A.A., Haag, R.°: Polyglycerol coated polypropylene surfaces for protein and
bacteria resistance. Polym. Chem. 6, 1350-1359 (2015) [published online 2014]
Matthes, M.#, Preusse, M.#, Zhang, J.#, Schechter, J., Mayer, D., Lentes, B., Theis, F.J., Prakash, N.,
Meyer, S.U., Stoecker, K., Sass, S., Theis, F.J., Pfaffl, M.W.°: Posttranscriptional regulatory networks: From
expression profiling to integrative analysis of mRNA and microRNA data. Methods Mol. Biol. 1160, 165-188
(2014)
Müller, J.°, Hense, B.A., Marozava, S., Kuttler, C., Meckenstock, R.U.: Model selection for microbial
nutrient uptake using a cost-benefit approach. Math. Biosci. 255, 52-70 (2014)
Neumann, S., Hasenauer, J., Pollak, N., Scheurich, P.°: Dominant negative effects of TNF-Related
Apoptosis-Inducing Ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric
complexes. J. Biol. Chem. 289, 16576-16587 (2014)
page 48 of 247
2015-11-23
#
joint first authors
Nielsen, T.H., Diaz, Z., Christodoulopoulos, R., Charbonneau, F., Qureshi, S., Rousseau, C., Benlimame, N.,
Camlioglu, E., Constantin, A.M., Oros, K.K., Krumsiek, J., Crump, M., Morin, R.D., Cerchietti, L., Johnson,
N.A., Petrogiannis-Haliotis, T., Miller, W.H., Assouline, S.E., Mann, K.K.°: Methods for sample acquisition
and processing of serial blood and tumor biopsies for multicenter diffuse large B-cell lymphoma clinical trials.
Cancer Epidemiol. Biomarkers Prev. 23, 2688-2693 (2014)
Pauly, O.°, Diotte, B., Fallavollita, P., Weidert, S., Euler, E., Navab, N.: Machine learning-based augmented
reality for improved surgical scene understanding. Comput. Med. Imaging Graph. 41, 55-60 (2014)
Peng, T., Wang, L., Bayer, C., Conjeti, S., Baust, M., Navab, N.A.: Shading correction for whole slide image
using low rank and sparse decomposition. Lecture Notes Comp. Sci. 8673, 33-40 (2014)
Peter, L., Mateus, D., Chatelain, P., Schworm, N., Stangl, S., Multhoff, G., Navab, N.: Leveraging random
forests for interactive exploration of large histological images. Lecture Notes Comp. Sci. 8673, 1-8 (2015)
Quaranta, M., Eyerich, S., Knapp, B., Nasorri, F., Scarponi, C., Mattii, M., Garzorz, N., Harlfinger, A.T.,
Jaeger, T., Grosber, M., Pennino, D., Mempel, M., Schnopp, C., Theis, F.J., Albanesi, C., Cavani, A.,
Schmidt-Weber, C.B., Ring, J., Eyerich, K.°: Allergic contact dermatitis in psoriasis patients: Typical,
delayed, and non-interacting. PLoS ONE 9:e101814 (2014)
Quaranta, M.#, Knapp, B.#, Garzorz, N., Mattii, M., Pullabhatla, V., Pennino, D., Andres, C.,
Traidl-Hoffmann, C., Cavani, A., Theis, F.J., Ring, J., Schmidt-Weber, C.B., Eyerich, S., Eyerich, K.°:
Intraindividual genome expression analysis reveals a specific molecular signature of psoriasis and eczema.
Sci. Transl. Med. 6:244ra90 (2014)
Röck, K., Tigges, J., Sass, S., Schütze, A., Florea, A.M., Fender, A.C., Theis, F.J., Krutmann, J., Boege, F.,
Fritsche, E., Reifenberger, G., Fischer, J.W.°: miR-23a-3p causes cellular senescence by targeting
hyaluronan synthase2: Possible implication for skin aging. J. Invest. Dermatol. 135, 369-377 (2014)
Roselius, L., Langemann, D., Müller, J., Hense, B.A., Filges, S., Jahn, D., Münch, R.°: Modeling and
analysis of a gene-regulatory feed-forward loop with basal expression of the second regulator. J. Theor. Biol.
363, 290-299 (2014)
Sass, S., Buettner, F., Müller, N.S., Theis, F.J.°: RAMONA: A web application for gene set analysis on
multilevel omics data. Bioinformatics 31, 128-130 (2015) [published online 2014]
Schmidt, A.M., Fagerer, S.R., Jefimovs, K., Buettner, F., Marro, C., Siringil, E.C., Boehlen, K.L., Pabst, M.,
Ibáñez, A.J.°: Molecular phenotypic profiling of a Saccharomyces cerevisiae strain at the single-cell level.
Analyst 139, 5709-5717 (2014)
page 49 of 247
2015-11-23
#
joint first authors
Shen, H.°, Xu, W., Peng, S., Scherb, H., She, J., Voigt, K., Alamdar, A., Schramm, K.-W.°: Pooling
samples for "top-down" molecular exposomics research: The methodology. Environ. Health 13:8 (2014)
Shin, S.Y.#, Fauman, E.B.#, Petersen, A.-K.#, Krumsiek, J.#, Santos, R., Huang, J., Arnold, M., Erte, I.,
Nat. Genet. 46, 543-550 (2014)
Storath, M., Weinmann, A.°: Fast partitioning of vector-valued images. SIAM J. Imaging Sci. 7, 1826-1852
(2014)
Storath, M.°, Weinmann, A.°, Frikel, J.°, Unser, M.°: Joint image reconstruction and segmentation using the
Potts model. Inverse Probl. 31:025003 (2015) [published online 2014]
Storath, M.°, Weinmann, A.°, Demaret, L.°: Jump-sparse and sparse recovery using potts functionals. IEEE
Trans. Signal Process. 62, 3654-3666 (2014)
Thalheimer, F.B., Wingert, S., de Giacomo, P., Haetscher, N., Rehage, M., Brill, B., Theis, F.J.,
Hennighausen, L., Schroeder, T., Rieger, M.A.°: Cytokine-regulated GADD45G induces differentiation and
lineage selection in hematopoietic stem cells. Stem Cell Rep. 3, 34-43 (2014)
Uecker, H., Müller, J.°, Hense, B.A.: Individual-based model for quorum sensing with background flow. Bull.
Math. Biol. 76, 1727-1746 (2014)
Vehlow, C.#°, Hasenauer, J.#°, Krämer, A., Raue, A., Hug, S., Timmer, J., Radde, N., Theis, F.J., Weiskopf,
D.: iVUN: Interactive Visualization of Uncertain biochemical reaction Networks. BMC Bioinformatics 14:S2
(2013)
Vinnikov, I.A.°, Hajdukiewicz, K., Reymann, J., Beneke, J., Czajkowski, R., Roth, L.C., Novak, M., Roller, A.,
Dörner, N., Starkuviene, V., Theis, F.J., Erfle, H., Schütz, G., Grinevich, V.°, Konopka, W.°: Hypothalamic
miR-103 protects from hyperphagic obesity in mice. J. Neurosci. 34, 10659-10674 (2014)
Vogel, J., Duliu, A.°, Oyamada, Y., Gardiazabal, J., Lasser, T., Ziai, M., Hein, R., Navab, N.A.: Towards
robust identification and tracking of nevi in sparse photographic time series. Proc. SPIE 9035:90353D (2014)
Waldera-Lupa, D.M., Kalfalah, F., Florea, A.M., Sass, S., Kruse, F.E., Rieder, V., Tigges, J., Fritsche, E.,
Krutmann, J., Busch, H., Boerries, M., Meyer, H.E., Boege, F., Theis, F.J., Reifenberger, G., Stühler, K.°:
Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts.
Aging 6, 856-878 (2014)
Weinmann, A., Demaret, L., Storath, M.°: Total variation regularization for manifold-valued data. SIAM J.
Imaging Sci. 7, 2226-2257 (2014)
page 50 of 247
2015-11-23
#
joint first authors
#
#
Winkler, C. , Krumsiek, J. , Buettner, F., Angermüller, C., Giannopoulou, E.Z., Theis, F.J., Ziegler,
Development 141, 514-525 (2014)
page 51 of 247
2015-11-23
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joint first authors
Institute of Developmental Genetics
Beckervordersandforth, R.°, Deshpande, A., Schäffner, I., Huttner, H.B., Lepier, A., Lie, D.C., Götz, M.: In
vivo targeting of adult neural stem cells in the dentate gyrus by a split-cre approach. Stem Cell Rep. 2,
153-162 (2014)
Blanco, S., Dietmann, S., Flores, J.V., Hussain, S., Kutter, C., Humphreys, P., Lukk, M., Lombard, P., Treps,
L., Popis, M., Kellner, S., Hölter, S.M., Garrett, L., Wurst, W., Becker, L., Klopstock, T., Fuchs, H.,
Gailus-Durner, V., Hrabě de Angelis, M., Káradóttir, R.T., Helm, M., Ule, J., Gleeson, J.G., Odom, D.T.,
Frye, M.°: Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders. EMBO J.
33, 2020-2039 (2014)
Conrad, M.°, Ingold, I., Buday, K., Kobayashi, S., Angeli, J.P.: ROS, thiols and thiol-regulating systems in
male gametogenesis. Biochim. Biophys. Acta-Gen. Subj. 1850, 1566-1574 (2015) [published online 2014]
Cremer, J.N.°, Amunts, K., Graw, J., Piel, M., Rösch, F., Zilles, K.: Neurotransmitter receptor density
changes in Pitx3AK mice - a model relevant to Parkinson's disease. Neuroscience 285, 11-23 (2014)
Dykes, I.M., van Bueren, K.L., Ashmore, R.J., Floß, T., Wurst, W., Szumska, D., Bhattacharya, S.,
Scambler, P.J.°: HIC2 is a novel dosage-dependent regulator of cardiac development located within the
distal 22q11 deletion syndrome region. Circ. Res. 115, 23-31 (2014)
Flinn, L.J., Keatinge, M., Bretaud, S., Mortiboys, H., Matsui, H., de Felice, E., Woodroof, H.I., Brown, L.,
McTighe, A., Soellner, R., Allen, C.E., Heath, P.R., Milo, M., Muqit, M.M.K., Reichert, A.S., Köster, R.W.,
Ingham, P.W., Bandmann, O.°: TigarB causes mitochondrial dysfunction and neuronal loss in PINK1
deficiency. Ann. Neurol. 74, 837-847 (2013)
1180-1191 (2014)
Gewies, A.#, Gorka, O.#, Bergmann, H., Pechloff, K., Petermann, F., Jeltsch, K.M., Rudelius, M.,
Kriegsmann, M., Weichert, W., Horsch, M., Beckers, J., Wurst, W., Heikenwälder, M., Korn, T.,
Heissmeyer, V., Ruland, J.°: Uncoupling Malt1 threshold function from paracaspase activity results in
destructive autoimmune inflammation. Cell Rep. 9, 1292-1305 (2014)
Giusti, S.A., Vogl, A.M., Brockmann, M.M., Vercelli, C.A., Rein, M.L., Trümbach, D., Wurst, W., Cazalla, D.,
Stein, V., Deussing, J.M., Refojo, D.°: MicroRNA-9 controls dendritic development by targeting REST. eLife
3:e02755 (2014)
Graw, J.°: Genetic models for cataracts. Drug Discov. Today Dis. Models 10, e189-e194 (2014)
page 52 of 247
2015-11-23
#
joint first authors
Huang, H., Koelle, P., Fendler, M., Schröttle, A., Czihal, M., Hoffmann, U., Conrad, M., Kuhlencordt, P.J.°:
Induction of inducible Nitric Oxide Synthase (iNOS) expression by oxLDL inhibits macrophage derived foam
cell migration. Atherosclerosis 235, 213-222 (2014)
Hüttl, R.E., Huber, A.B.°: Quantitative analysis of axonal outgrowth in mice. Neuromethods 87, 145-162
(2014)
Kandasamy, M., Lehner, B., Kraus, S., Sander, P.R., Marschallinger, J., Rivera, F.J., Trümbach, D.,
Ueberham, U., Reitsamer, H.A., Strauss, O., Bogdahn, U., Couillard-Despres, S., Aigner, L.°: TGF-beta
signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new
neurons. J. Cell. Mol. Med. 18, 1444-1459 (2014)
2014]
I299F
Knier, B., Rothhammer, V., Heink, S., Puk, O., Graw, J., Hemmer, B., Korn, T.°: Neutralizing IL-17 protects
the optic nerve from autoimmune pathology and prevents retinal nerve fiber layer atrophy during
experimental autoimmune encephalomyelitis. J. Autoimmun. 56, 34-44 (2015) [published online 2014]
PLoS ONE 9:e104568 (2014)
Lewerenz, J.°, Baxter, P.S., Kassubek, R., Albrecht, P., van Liefferinge, J., Westhoff, M.A., Halatsch, M.E.,
Karpel-Massler, G., Meakin, P.J., Hayes, J.D., Aronica, E.M., Smolders, I., Ludolph, A.C., Methner, A.,
Conrad, M., Massie, A., Hardingham, G.E., Maher, P.A.°: Phosphoinositide 3-kinases upregulate system xc via eukaryotic initiation factor 2α and activating transcription factor 4-A pathway active in glioblastomas and
epilepsy. Antioxid. Redox Signal. 20, 2907-2922 (2014)
page 53 of 247
2015-11-23
#
joint first authors
Matsui, H.°, Namikawa, K., Babaryka, A., Köster, R.W.: Functional regionalization of the teleost cerebellum
analyzed in vivo. Proc. Natl. Acad. Sci. U.S.A. 111, 11846-11851 (2014)
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Matthes, M. , Preusse, M. , Zhang, J. , Schechter, J., Mayer, D., Lentes, B., Theis, F.J., Prakash, N.,
Meier, F.#, Giesert, F.H.H.#, Delic, S.#, Faus-Kessler, T., Matheus, F., Simeone, A., Hölter, S.M., Kühn,
R., Vogt Weisenhorn, D.M., Wurst, W.°, Prakash, N.°: FGF/FGFR2 signaling regulates the generation and
correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS ONE 9:e101124 (2014)
Nehls, J., Koppensteiner, H., Brack-Werner, R., Floss, T., Schindler, M.: HIV-1 replication in human
immune cells is independent of TAR DNA binding Protein 43 (TDP-43) expression. PLoS ONE 9:e105478
(2014)
O'Flanagan, C.H., Morais, V.A., Wurst, W., de Strooper, B., O'Neill, C.°: The Parkinson's gene PINK1
regulates cell cycle progression and promotes cancer-associated phenotypes. Oncogene 34, 1363-1374
Peng, X., Mandal, P.K., Kaminskyy, V.O., Lindqvist, A., Conrad, M., Arner, E.S.J.°: Sec-containing TrxR1 is
essential for self-sufficiency of cells by control of glucose-derived H2O2. Cell Death Dis. 5:e1235 (2014)
Pertek, A., Meier, F., Irmler, M., Beckers, J., Skylaki, S., Endele, M., Wurst, W., Prakash, N., Kühn, R.°:
Simple derivation of transgene-free iPS cells by a dual recombinase approach. Mol. Biotechnol. 56, 697-713
(2014)
Piccoli, G., Onofri, F., Cirnaru, M.D., Kaiser, C.J., Jagtap, P.K., Kastenmüller, A., Pischedda, F., Marte, A.,
von Zweydorf, F., Vogt, A., Giesert, F.H.H., Pan, L., Antonucci, F., Kiel, C., Zhang, M., Weinkauf, S.,
Sattler, M., Sala, C., Matteoli, M., Ueffing, M., Gloeckner, C.J.°: Leucine-rich repeat kinase 2 binds to
neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain. Mol. Cell. Biol. 34,
2147-2161 (2014)
page 54 of 247
2015-11-23
#
joint first authors
Pischedda, F., Szczurkowska, J., Cirnaru, M.D., Giesert, F.H.H., Vezzoli, E., Ueffing, M., Sala, C.,
Francolini, M., Hauck, S.M., Cancedda, L., Piccoli, G.°: A cell surface biotinylation assay to reveal
membrane-associated neuronal cues: Negr1 regulates dendritic arborization. Mol. Cell. Proteomics 13,
733-748 (2014)
Polzer, H., Volkmer, E., Saller, M., Prall, W.C., Haasters, F., Drosse, I., Wilhelmi, A., Mutschler, W.,
Schieker, M.: Comparison of different strategies for in vivo seeding of prevascularized scaffolds. Tissue Eng.
Part C Meth. 20, 11-18 (2014)
DJ-1. J. Proteome Res. 13, 2339-2351 (2014)
Ramin, M., Bürger, A., Hörlein, A., Kerkau, D., von Walcke-Wulffen, V., Nicklas, W., Schenkel, J.°: Stability
of cryopreserved samples of mutant mice. Biopreserv. Biobank. 12, 343-350 (2014)
Schötz, U., Deliolanis, N., Ng, D., Pauli, J., Resch-Genger, U., Kühn, E., Heuer, S., Beisker, W., Köster,
R.W., Zitzelsberger, H., Caldwell, R.B.°: Usefulness of a darwinian system in a biotechnological
application: Evolution of optical window fluorescent protein variants under selective pressure. PLoS ONE
9:e107069 (2014)
Sotnikov, S.°, Wittmann, A., Bunck, M., Bauer, S., Deussing, J.M., Schmidt, M., Touma, C., Landgraf, R.,
Czibere, L.: Blunted HPA axis reactivity reveals glucocorticoid system dysbalance in a mouse model of high
anxiety-related behavior. Psychoneuroendocrinol. 48, 41-51 (2014)
Sotnikov, S.V.°, Chekmareva, N.Y., Schmid, B., Harbich, D., Malik, V., Bauer, S., Kuehne, C., Markt, P.O.,
Deussing, J.M., Schmidt, M.V., Landgraf, R.: Enriched environment impacts trimethylthiazoline-induced
anxiety-related behavior and immediate early gene expression: Critical role of Crhr1. Eur. J. Neurosci. 40,
2691-2700 (2014)
page 55 of 247
2015-11-23
#
joint first authors
#
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Spieler, D. , Kaffe, M. , Knauf, F. , Bessa, J., Tena, J.J., Giesert, F.H.H., Schormair, B., Tilch, E., Lee, H.,
Steib, K., Schäffner, I., Jagasia, R., Ebert, B., Lie, D.C.°: Mitochondria modify exercise-induced
development of stem cell-derived neurons in the adult brain. J. Neurosci. 34, 6624-6633 (2014)
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Stribl, C.B. , Samara, A. , Trümbach, D. , Augustin, R., Neumann, M., Fuchs, H., Gailus-Durner, V.,
Thor, T.°, Künkele, A., Pajtler, K.W., Wefers, A.K., Stephan, H., Mestdagh, P., Heukamp, L., Hartmann, W.,
Vandesompele, J., Sadowski, N., Becker, L., Garrett, L., Hölter, S.M., Horsch, M., Calzada-Wack, J.,
Klein-Rodewald, T., Rácz, I., Zimmer, A., Beckers, J., Neff, F., Klopstock, T., de Antonellis, P., Zollo, M.,
Wurst, W., Fuchs, H., Gailus-Durner, V., Schüller, U., Hrabě de Angelis, M., Eggert, A., Schramm, A.,
Schulte, J.H.°: MiR-34a deficiency accelerates medulloblastoma formation in vivo. Int. J. Cancer 136,
2293-2303 (2014)
Tiedemann, H.B., Schneltzer, E., Zeiser, S., Wurst, W., Beckers, J., Przemeck, G.K.H., Hrabě de
Angelis, M.°: Fast synchronization of ultradian oscillators controlled by Delta-Notch signaling with
Cis-inhibition. PLoS Comput. Biol. 10:e1003843 (2014)
Toyoda, Y.#, Erkut, C.#, Pan-Montojo, F.#, Boland, S., Stewart, M.P., Müller, D.J., Wurst, W., Hyman, A.A.°,
Kurzchalia, T.V.°: Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate,
support mitochondrial membrane potential and neuronal survival. Biol. Open 3, 777-784 (2014)
Trümbach, D., Prakash, N.°: The conserved miR-8/miR-200 microRNA family and their role in invertebrate
and vertebrate neurogenesis. Cell Tissue Res. 359, 161-177 (2015) [published online 2014]
Wefers, B., Ortiz, O., Wurst, W., Kühn, R.°: Generation of targeted mouse mutants by embryo
microinjection of TALENs. Methods 69, 94-101 (2014)
Wirth, E.K., Bharathi, B.S., Hatfield, D.L., Conrad, M., Brielmeier, M., Schweizer, U.°: Cerebellar hypoplasia
in mice lacking selenoprotein biosynthesis in neurons. Biol. Trace Elem. Res. 158, 203-210 (2014)
page 56 of 247
2015-11-23
#
joint first authors
Yan, X., Sabrautzki, S., Horsch, M., Fuchs, H., Gailus-Durner, V., Beckers, J., Hrabě de Angelis, M.,
Graw, J.°: Peroxidasin is essential for eye development in the mouse. Hum. Mol. Genet. 23, 5597-5614
(2014)
Zimprich, A., Garett, L., Deussing, J.M., Wotjak, C.T., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis,
M., Wurst, W., Hölter, S.M.°: A robust and reliable non-invasive test for stress responsivity in mice. Front.
Behav. Neurosci. 8:125 (2014)
Zumbrennen-Bullough, K.B., Becker, L., Garrett, L., Hölter, S.M., Calzada-Wack, J., Mossbrugger, I.,
Quintanilla-Fend, L., Rácz, I., Rathkolb, B., Klopstock, T., Wurst, W., Zimmer, A., Wolf, E., Fuchs, H.,
Gailus-Durner, V., Hrabě de Angelis, M., Romney, S.J., Leibold, E.A.°: Abnormal brain iron metabolism in
Irp2 deficient mice is associated with mild neurological and behavioral impairments. PLoS ONE 9:e98072
(2014)
page 57 of 247
2015-11-23
#
joint first authors
Institute of Diabetes and Obesity
Al-Massadi, O., Lear, P.V., Müller, T.D., Lopez, M.A., Dieguez, C., Tschöp, M.H., Nogueiras, R.°: Review of
novel aspects of the regulation of ghrelin secretion. Curr. Drug Metab. 15, 398-413 (2014)
Aoqui, C., Chmielewski, S., Scherer, E., Eissler, R., Sollinger, D., Heid, I., Braren, R., Schmaderer, C.,
Megens, R.T., Weber, C., Heemann, U., Tschöp, M.H., Baumann, M.°: Microvascular dysfunction in the
course of metabolic syndrome induced by high-fat diet. Cardiovasc. Diabetol. 13:31 (2014)
Care 37, e194-e195 (2014)
Brockmann, A., Strittmatter, T., May, S., Stemmer, K., Marx, A., Brunner, T.°: Structure-function relationship
of thiazolide-induced apoptosis in colorectal tumor cells. ACS Chem. Biol. 9, 1520-1527 (2014)
Busse, S., Lutter, D., Heldmaier, G., Jastroch, M., Meyer, C.W.°: Torpor at high ambient temperature in a
neotropical didelphid, the grey short-tailed opossum (Monodelphis domestica). Naturwissenschaften 101,
1003-1006 (2014)
Cansell, C., Castel, J., Denis, R.G., Rouch, C., Delbes, A.S., Martinez, S., Mestivier, D., Finan, B.,
Maldonado-Aviles, J.G., Rijnsburger, M., Tschöp, M.H., Dileone, R.J., Eckel, R.H., la Fleur, S.E., Magnan,
C., Hnasko, T.S., Luquet, S.°: Dietary triglycerides act on mesolimbic structures to regulate the rewarding
and motivational aspects of feeding. Mol. Psychiatry 19, 1095-1105 (2014)
Divakaruni, A.S., Paradyse, A., Ferrick, D.A., Murphy, A.N., Jastroch, M.°: Analysis and interpretation of
microplate-based oxygen consumption and pH data. Methods Enzymol. 547, 309-354 (2014)
page 58 of 247
2015-11-23
#
joint first authors
Finan, B.°, Yang, B., Ottaway, N., Smiley, D.L., Ma, T., Clemmensen, C., Chabenne, J., Zhang, L.,
Habegger, K.M., Fischer, K., Campbell, J.E., Sandoval, D.A., Seeley, R.J., Bleicher, K., Uhles, S., Riboulet,
W., Funk, J., Hertel, C., Belli, S., Sebokova, E., Conde-Knape, K., Konkar, A., Drucker, D.J., Gelfanov, V.,
Pfluger, P.T., Müller, T.D., Perez-Tilve, D., DiMarchi, R.D.°, Tschöp, M.H.°: A rationally designed
monomeric peptide triagonist corrects obesity and diabetes in rodents. Nat. Med. 21, 27-36 (2015) [published
online 2014]
Fuchs, Y.F.#, Adler, K.#, Lindner, A., Karasinsky, A., Wilhelm, C., Weigelt, M., Balke, H., Förtsch, K.,
vaccination induce CD8+ T cell mediated autoimmune diabetes in the RIP-CD80GP mouse. Clin. Exp.
Immunol. 176, 199-206 (2014)
Gustems, M.°, Woellmer, A., Rothbauer, U., Eck, S.H., Wieland, T., Lutter, D., Hammerschmidt, W.:
c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence
motifs. Nucleic Acids Res. 42, 3059-3072 (2014)
Gutierrez-Aguilar, R., Kim, D., Casimir, M., Dai, X., Pfluger, P.T., Park, J., Haller, A., Donelan, E., D'Alessio,
D., Woods, S.C., MacDonald, P.E., Seeley, R.J.°: The role of the transcription factor ETV5 in insulin
exocytosis. Diabetologia 57, 383-391 (2014)
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Hernandez, E.D. , Lee, S.J. , Kim, J.Y., Duran, A., Linares, J.F., Yajima, T., Müller, T.D., Tschöp, M.H.,
Smith, S.R., Diaz-Meco, M.T., Moscat, J.°: A macrophage NBR1-MEKK3 complex triggers JNK-mediated
adipose tissue inflammation in obesity. Cell Metab. 20, 499-511 (2014)
Jastroch, M.°, Keipert, S., Perocchi, F.: From explosives to physiological combustion: Next generation
chemical uncouplers. Mol. Metab. 3, 86-87 (2014)
Jastroch, M., Morin, S., Tschöp, M.H., Yi, C.-X.°: The hypothalamic neural-glial network and the metabolic
syndrome. Best Pract. Res. Clin. Endocrinol. Metab. 28, 661-671 (2014)
Keipert, S., Jastroch, M.°: Brite/beige fat and UCP1 - is it thermogenesis? Biochim. Biophys.
Acta-Bioenerg. 1837, 1075-1082 (2014)
Keipert, S.°, Ost, M., Johann, K., Imber, F., Jastroch, M., van Schothorst, E.M., Keijer, J., Klaus, S.:
Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a
myokine. Am. J. Physiol. Endocrinol. Metab. 306, E469-E482 (2014)
Kim, J.G., Suyama, S., Koch, M., Jin, S., Argente-Arizon, P., Argente, J., Liu, Z.W., Zimmer, M.R., Jeong,
J.K., Szigeti-Buck, K., Gao, Y., García-Cáceres, C., Yi, C.-X., Salmaso, N., Vaccarino, F.M., Chowen, J.,
Diano, S., Dietrich, M.O., Tschöp, M.H., Horvath, T.L.°: Leptin signaling in astrocytes regulates
hypothalamic neuronal circuits and feeding. Nat. Neurosci. 17, 908-910 (2014)
page 59 of 247
2015-11-23
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joint first authors
Morselli, E., Fuente-Martin, E., Finan, B., Kim, M., Frank, A., García-Cáceres, C., Navas, C.R., Gordillo, R.,
Neinast, M., Paretzke, H.G., Li, D.L., Gao, Y., Yi, C.-X., Hahner, L., Palmer, B.F., Tschöp, M.H., Clegg,
D.J.°: Hypothalamic PGC-1α protects against high-fat diet exposure by regulating ERα. Cell Rep. 9, 633-645
(2014)
Mühlhaus, J., Dinter, J., Nürnberg, D., Rehders, M., Depke, M., Golchert, J., Homuth, G., Yi, C.-X., Morin,
S., Köhrle, J., Brix, K., Tschöp, M.H., Kleinau, G., Biebermann, H.: Analysis of human TAAR8 and murine
Taar8b mediated signaling pathways and expression profile. Int. J. Mol. Sci. 15, 20638-20655 (2014)
Müller, A., Leinweber, B., Fischer, J., Müller, T.D., Grüters, A., Tschöp, M.H., Knäuper, V., Biebermann, H.°,
Kleinau, G.°: The extracellular N-terminal domain of G-protein coupled receptor 83 regulates signaling
properties and is an intramolecular inverse agonist. BMC Res. Notes 7:913 (2014)
Oelkrug, R., Götze, N., Meyer, C.W., Jastroch, M.°: Antioxidant properties of UCP1 are evolutionary
conserved in mammals and buffer mitochondrial reactive oxygen species. Free Radic. Biol. Med. 77,
210-216 (2014)
Schwenk, R.W.°, Baumeier, C., Finan, B., Kluth, O., Brauer, C., Joost, H.G., DiMarchi, R.D., Tschöp, M.H.,
Schürmann, A.: GLP-1–oestrogen attenuates hyperphagia and protects from beta cell failure in
diabetes-prone New Zealand Obese (NZO) mice. Diabetologia 58, 604-614 (2015) [published online 2014]
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Stemmer, K.°, Kotzbeck, P., Zani, F., Bauer, M., Neff, C., Müller, T.D., Pfluger, P.T., Seeley, R.J.,
Divanovic, S.: Thermoneutral housing is a critical factor for immune function and diet-induced obesity in
C57BL/6 nude mice. Int. J. Obes. 39, 791-797 (2015) [published online 2014]
Tong, J.°, Davis, H.W., Summer, S., Benoit, S.C., Haque, A., Bidlingmaier, M., Tschöp, M.H., D'Alessio, D.:
Acute administration of unacylated ghrelin has no effect on basal or stimulated insulin secretion in healthy
humans. Diabetes 63, 2309-2319 (2014)
Ussar, S., Lee, K.Y., Dankel, S.N., Boucher, J., Haering, M.-F., Kleinridders, A., Thomou, T., Xue, R.,
Macotela, Y., Cypess, A.M., Tseng, Y.H., Mellgren, G., Kahn, C.R.°: ASC-1, PAT2, and P2RX5 are cell
surface markers for white, beige, and brown adipocytes. Sci. Transl. Med. 6:245ra94 (2014)
Ussar, S.°, Tschöp, M.H.°: [Br]eaking FAt. Cell 159, 238-240 (2014)
Winkler, C.#, Krumsiek, J.#, Buettner, F., Angermüller, C., Giannopoulou, E.Z., Theis, F.J., Ziegler,
Wolf, M.J., Adili, A., Piotrowitz, K., Abdullah, Z., Boege, Y., Stemmer, K., Ringelhan, M., Simonavicius,
N., Egger, M., Wohlleber, D., Lorentzen, A.R., Einer, C., Schulz, S., Clavel, T., Protzer, U., Thiele, C.,
Zischka, H., Moch, H., Tschöp, M.H., Tumanov, A.V., Haller, D., Unger, K., Karin, M., Kopf, M., Knolle, P.,
+
Weber, A.°, Heikenwälder, M.°: Metabolic activation of intrahepatic CD8 T cells and NKT cells causes
nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes. Cancer Cell 26, 549-564 (2014)
Development 141, 514-525 (2014)
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Institute of Diabetes and Regeneration Research
cells. eLife 3:e03842 (2014)
Gerdes, J.M., Christou-Safina, S., Xiong, Y., Moede, T., Moruzzi, N., Karlsson-Edlund, P., Leibiger, B.,
Leibiger, I., Ostenson, C.G., Beales, P., Berggren, P.O.°: Ciliary dysfunction impairs beta-cell insulin
secretion and promotes development of type 2 diabetes in rodents. Nat. Commun. 5:5308 (2014)
#
#
Goldman, O. , Han, S. , Hamou, W., Jodon de Villeroche, V., Uzan, G., Lickert, H., Gouon-Evans, V.°:
Endoderm generates endothelial cells during liver development. Stem Cell Rep. 3, 556-565 (2014)
Matthes, M.#, Preusse, M.#, Zhang, J.#, Schechter, J., Mayer, D., Lentes, B., Theis, F.J., Prakash, N.,
Moruzzi, N.°, Del Sole, M., Fato, R., Gerdes, J.M., Berggren, P.O., Bergamini, C., Brismar, K.: Short and
prolonged exposure to hyperglycaemia in human fibroblasts and endothelial cells: Metabolic and osmotic
effects. Int. J. Biochem. Cell Biol. 53, 66-76 (2014)
#
#
Development 141, 514-525 (2014)
page 62 of 247
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Institute of Diabetes Research and Metabolic Diseases
Besedovsky, L., Linz, B., Dimitrov, S., Groch, S., Born, J., Lange, T.°: Cortisol increases CXCR4 expression
but does not affect CD62L and CCR7 levels on specific T cell subsets in humans. Am. J. Physiol. Endocrinol.
Metab. 306, E1322-E1329 (2014)
9:e93148 (2014)
#
#
Eichner, J. , Rosenbaum, L. °, Wrzodek, C., Häring, H.-U., Zell, A., Lehmann, R.°: Integrated enrichment
analysis and pathway-centered visualization of metabolomics, proteomics, transcriptomics, and genomics
data by using the InCroMAP software. J. Chromatogr. B 966, 77-82 (2014)
Frank, S.°, Wilms, B., Veit, R., Ernst, B., Thurnheer, M., Kullmann, S., Fritsche, A., Birbaumer, N., Preissl,
H., Schultes, B.: Altered brain activity in severely obese women may recover after Roux-en Y gastric bypass
surgery. Int. J. Obes. 38, 341-348 (2014)
Hege, M.A.°, Stingl, K.T., Kullmann, S., Schag, K., Giel, K.E., Zipfel, S., Preissl, H.: Attentional impulsivity
in binge eating disorder modulates response inhibition performance and frontal brain networks. Int. J. Obes.
39, 353-360 (2015) [published online 2014]
Hege, M.A., Stingl, K.T., Ketterer, C., Häring, H.-U., Heni, M., Fritsche, A.°, Preissl, H.: Working
memory-related brain activity is associated with outcome of lifestyle intervention. Obesity 21, 2488-2494
(2013)
Heni, M., Wagner, R.°, Kullmann, S., Veit, R., Mat-Husin, H., Linder, K., Benkendorff, C., Peter, A., Stefan,
N., Häring, H.-U., Preissl, H., Fritsche, A.: Central insulin administration improves whole-body insulin
sensitivity via hypothalamus and parasympathetic outputs in men. Diabetes 63, 4083-4088 (2014)
Heni, M.#, Schöpfer, P.#, Peter, A.#, Sartorius, T., Fritsche, A.°, Synofzik, M., Häring, H.-U., Maetzler, W.,
Hennige, A.M.: Evidence for altered transport of insulin across the blood-brain barrier in insulin-resistant
humans. Acta Diabetol. 51, 679-681 (2013)
Heni, M., Kullmann, S.°, Veit, R., Ketterer, C., Frank, S., Machicao, F., Staiger, H., Häring, H.-U., Preissl,
H., Fritsche, A.: Variation in the obesity risk gene FTO determines the postprandial cerebral processing of
food stimuli in the prefrontal cortex. Mol. Metab. 3, 109-113 (2014)
Hoene, M.#, Li, J.#, Häring, H.-U., Weigert, C., Xu, G., Lehmann, R.°: The lipid profile of brown adipose
tissue is sex-specific in mice. Biochim. Biophys. Acta-Mol. Cell Biol. Lipids 1841, 1563-1570 (2014)
Jacobs, S., Schiller, K., Jansen, E., Fritsche, A., Weikert, C., di Giuseppe, R., Boeing, H., Schulze, M.B.,
Kröger, J.°: Association between erythrocyte membrane fatty acids and biomarkers of dyslipidemia in the
EPIC-Potsdam study. Eur. J. Clin. Nutr. 68, 517-525 (2014)
page 63 of 247
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Clin. Nutr. 100, 891-900 (2014)
Ketterer, C., Heni, M., Stingl, K.T., Tschritter, O., Linder, K., Wagner, R., Machicao, F., Häring, H.-U.,
Preissl, H., Staiger, H., Fritsche, A.°: Polymorphism rs3123554 in CNR2 reveals gender-specific effects on
body weight and affects loss of body weight and cerebral insulin action. Obesity 22, 925-931 (2014)
Klement, J.°, Mergelkuhl, B., Born, J., Lehnert, H., Hallschmid, M.: Role of γ-aminobutyric acid signalling in
the attenuation of counter-regulatory hormonal responses after antecedent hypoglycaemia in healthy men.
Diabetes Obes. Metab. 16, 1274-1278 (2014)
1361, 209-216 (2014)
Kullmann, S.°, Giel, K.E., Teufel, M., Thiel, A., Zipfel, S., Preissl, H.: Aberrant network integrity of the
inferior frontal cortex in women with anorexia nervosa. Neuroimage: Clin. 4, 615-652 (2014)
Kullmann, S.°, Giel, K.E., Hu, X., Bischoff, S.C., Teufel, M., Thiel, A., Zipfel, S., Preissl, H.: Impaired
inhibitory control in anorexia nervosa elicited by physical activity stimuli. Soc. Cogn. Affect. Neurosci. 9,
917-923 (2014)
Kullmann, S.°, Heni, M., Linder, K., Zipfel, S., Häring, H.-U., Veit, R., Fritsche, A., Preissl, H.:
Resting-state functional connectivity of the human hypothalamus. Hum. Brain Mapp. 35, 6088-6096 (2014)
Linder, K., Schleger, F., Ketterer, C., Fritsche, L., Kiefer-Schmidt, I., Hennige, A.M., Häring, H.-U.,
Preissl, H.°, Fritsche, A.: Maternal insulin sensitivity is associated with oral glucose-induced changes in
fetal brain activity. Diabetologia 57, 1192-1198 (2014)
Linder, K.#, Springer, F.#, Machann, J., Schick, F., Fritsche, A., Häring, H.-U., Blumenstock, G., Ranke,
M.B., Stefan, N., Binder, G., Ehehalt, S.°: Relationships of body composition and liver fat content with insulin
resistance in obesity-matched adolescents and adults. Obesity 13, 733-748 (2014)
Lutz, S.Z., Staiger, H., Fritsche, A., Häring, H.-U.°: Antihyperglycaemic therapies and cancer risk. Diab.
Vasc. Dis. Res. 11, 371-389 (2014)
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Lutz, S.Z., Franck, O., Böhm, A., Machann, J., Schick, F., Machicao, F., Fritsche, A., Häring, H.-U.°,
Staiger, H.: Common genetic variation in the human CTF1 locus, encoding cardiotrophin-1, determines
insulin sensitivity. PLoS ONE 9:e100391 (2014)
Ott, V., Lehnert, H., Staub, J., Wönne, K., Born, J., Hallschmid, M.°: Central nervous insulin administration
does not potentiate the acute glucoregulatory impact of concurrent mild hyperinsulinemia. Diabetes 64,
Peter, A.°, Kovarova, M., Nadalin, S., Cermak, T., Königsrainer, A., Machicao, F., Stefan, N., Häring, H.-U.,
Schleicher, E.: PNPLA3 variant I148M is associated with altered hepatic lipid composition in humans.
Diabetologia 57, 2103-2107 (2014)
Sartorius, T.°, Peter, A., Schulz, N., Drescher, A., Bergheim, I., Machann, J., Schick, F., Siegel-Axel, D.,
Schürmann, A., Weigert, C., Häring, H.-U., Hennige, A.M.: Cinnamon extract improves insulin sensitivity in
the brain and lowers liver fat in mouse models of obesity. PLoS ONE 9:e92358 (2014)
Schleger, F.°, Landerl, K., Muenssinger, J., Draganova, R., Reinl, M., Kiefer-Schmidt, I., Weiss, M.,
Wacker-Gussmann, A., Huotilainen, M., Preissl, H.: Magnetoencephalographic signatures of numerosity
discrimination in fetuses and neonates. Dev. Neuropsychol. 39, 316-329 (2014)
Siegel-Axel, D.I.°, Ullrich, S., Stefan, N., Rittig, K., Gerst, F., Klingler, C., Schmidt, U., Schreiner, B.,
Randrianarisoa, E., Schaller, H.E., Stock, U.A., Weigert, C., Königsrainer, A., Häring, H.-U.: Fetuin-a
influences vascular cell growth and production of proinflammatory and angiogenic proteins by human
perivascular fat cells. Diabetologia 57, 1057-1066 (2014)
Stefan, N.°, Sun, Q., Fritsche, A., Machann, J., Schick, F., Gerst, F., Jeppesen, C., Joost, H.G., Hu, F.B.,
Boeing, H., Ullrich, S., Häring, H.-U., Schulze, M.B.: Impact of the adipokine adiponectin and the
hepatokine fetuin-a on the development of type 2 diabetes: Prospective cohort- and cross-sectional
phenotyping studies. PLoS ONE 9:e92238 (2014)
Stefan, N.°, Ramsauer, M., Jordan, P., Nowotny, B., Kantartzis, K., Machann, J., Hwang, J.H., Nowotny,
P., Kahl, S., Harreiter, J., Hornemann, S., Sanyal, A.J., Stewart, P.M., Pfeiffer, A.F., Kautzky-Willer, A.,
Roden, M., Häring, H.-U., Fürst-Recktenwald, S.: Inhibition of 11β-HSD1 with RO5093151 for non-alcoholic
fatty liver disease: A multicentre, randomised, double-blind, placebo-controlled trial. Lancet Diabet.
Endocrinol. 2, 406-416 (2014)
Teutsch, C.A., Panse, M., Grundmann, M., Kaiser, G., Kostenis, E., Häring, H.-U., Ullrich, S.°: Detection of
free fatty acid receptor 1 expression: The critical role of negative and positive controls. Diabetologia 57,
776-780 (2014)
Veit, R.#°, Kullmann, S.#, Heni, M., Machann, J., Häring, H.-U., Fritsche, A., Preissl, H.: Reduced cortical
thickness associated with visceral fat and BMI. Neuroimage: Clin. 6, 307-311 (2014)
page 65 of 247
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Wagner, R., Li, J., Kenar, E., Kohlbacher, O., Machicao, F., Häring, H.-U., Fritsche, A., Xu, G.°, Lehmann,
R.°: Clinical and non-targeted metabolomic profiling of homozygous carriers of transcription factor 7-like 2
variant rs7903146. Sci. Rep. 4:5296 (2014)
Wagner, R., Hieronimus, A., Lamprinou, A., Heni, M., Hatziagelaki, E., Ullrich, S., Stefan, N., Staiger, H.,
Häring, H.-U., Fritsche, A.°: Peroxisome Proliferator-Activated Receptor Gamma (PPARG) modulates Free
Fatty Acid Receptor 1 (FFAR1) dependent insulin secretion in humans. Mol. Metab. 3, 676-680 (2014)
Wagner, R., Häring, H.-U., Fritsche, A.: Phänotypen des Prädiabetes und des Typ-2-Diabetes. Dtsch. Med.
Wochenschr. 139, 1109-1113 (2014)
Wagner, R., Staiger, H., Ullrich, S., Stefan, N., Fritsche, A., Häring, H.-U.°: Untangling the interplay of
genetic and metabolic influences on beta-cell function: Examples of potential therapeutic implications
involving TCF7L2 and FFAR1. Mol. Metab. 3, 261-267 (2014)
Weigert, C., Lehmann, R., Hartwig, S., Lehr, S.°: The secretome of the working human skeletal muscle - a
promising opportunity to combat the metabolic disaster? Proteomics Clin. Appl. 8, 5-18 (2014)
page 66 of 247
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Institute of Diabetes Research Type 1
Achenbach, P., Winkler, C., Haupt, F., Beyerlein, A., Ziegler, A.-G.°: Prädisposition, frühe Stadien und
Phänotypen des Typ-1-Diabetes. Dtsch. Med. Wochenschr. 139, 1100-1104 (2014)
Bender, C.°, Schlosser, M., Christen, U., Ziegler, A.-G., Achenbach, P.°: GAD autoantibody affinity in
schoolchildren from the general population. Diabetologia 57, 1911-1918 (2014)
Beyerlein, A., Thiering, E., Pflueger, M., Bidlingmaier, M., Stock, J., Knopff, A., Winkler, C., Heinrich, J.,
Ziegler, A.-G.°: Early infant growth is associated with the risk of islet autoimmunity in genetically susceptible
children. Pediatr. Diabetes 15, 534-542 (2014)
Beyerlein, A.°: Quantile regression-opportunities and challenges from a user's perspective. Am. J.
Epidemiol. 180, 330-331 (2014)
Care 37, e194-e195 (2014)
Chmiel, R., Beyerlein, A., Knopff, A., Hummel, S., Ziegler, A.-G.°, Winkler, C.: Early infant feeding and
risk of developing islet autoimmunity and type 1 diabetes. Acta Diabetol. 52, 621-624 (2015) [published
online 2014]
Couper, J.J.°, Haller, M.J., Ziegler, A.-G., Knip, M., Ludvigsson, J., Craig, M.E.: Phases of type 1 diabetes in
children and adolescents. Pediatr. Diabetes 15, 18-25 (2014)
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#
Fuchs, Y.F. , Adler, K. , Lindner, A., Karasinsky, A., Wilhelm, C., Weigelt, M., Balke, H., Förtsch, K.,
+
vaccination induce CD8 T cell mediated autoimmune diabetes in the RIP-CD80GP mouse. Clin. Exp.
Immunol. 176, 199-206 (2014)
Giannopoulou, E.Z., Puff, R., Beyerlein, A., von Luettichau, I., Boerschmann, H., Schatz, D., Atkinson, M.,
Haller, M.J., Egger, D., Burdach, S., Ziegler, A.-G.°: Effect of a single autologous cord blood infusion on
beta-cell and immune function in children with new onset type 1 diabetes: A non-randomized, controlled trial.
Pediatr. Diabetes 15, 100-109 (2014)
Hummel, S.°, Vehik, K., Uusitalo, U., McLeod, W., Aronsson, C.A., Frank, N., Gesualdo, P., Yang, J., Norris,
J.M., Virtanen, S.M., TEDDY Study Group (Ziegler, A.-G., Beyerlein, A., Bonifacio, E., Hummel, M.,
Foterek, K., Kersting, M., Knopff, A., Koletzko, S., Peplow, C., Roth, R., Stock, J., Strauss, E.,
Warncke, K., Winkler, C.): Infant feeding patterns in families with a diabetes history - observations from The
Environmental Determinants of Diabetes in the Young (TEDDY) birth cohort study. Public Health Nutr. 17,
2853-2862 (2014)
Johnson, S.B.°, Lynch, K.F., Lee, H.-S., Smith, L., Baxter, J., Lernmark, B., Roth, R., Simell, T.: At high risk
for early withdrawal: Using a cumulative risk model to increase retention in the first year of the TEDDY study.
J. Clin. Epidemiol. 67, 609-611 (2014)
Jung, N.°, Pereira, B., Nehring, I., Brix, O., Bernius, P.A., Schroeder, S.A., Kluger, G.J., Koehler, T.,
Beyerlein, A., Weir, S., von Kries, R., Narayanan, U.G., Berweck, S., Mall, V.: Does hip displacement
influence health-related quality of life in children with cerebral palsy? Dev. Neurorehabil. 17, 420-425 (2014)
Jung, N.H., Brix, O., Bernius, P., Schroeder, A.S., Kluger, G.J., Beyerlein, A., Weir, S., von Kries, R.,
Narayanan, U.G., Mall, V., Berweck, S.°: German translation of the caregiver priorities and child health index
of life with disabilities questionnaire: Test-retest reliability and correlation with gross motor function in
children with cerebral palsy. Neuropediatrics 45, 289-293 (2014)
Kemppainen, K.M., Ardissone, A.N., Davis-Richardson, A.G., Fagen, J.R., Gano, K.A., León-Novelo, L.G.,
Vehik, K., Casella, G., Simell, O., Ziegler, A.-G., Rewers, M.J., Lernmark, A., Hagopian, W., She, J.X.,
Krischer, J.P., Akolkar, B., Schatz, D.A., Atkinson, M.A., Triplett, E.W.°, TEDDY Study Group (Beyerlein, A.,
Roth, R., Stock, J., Strauss, E., Warncke, K., Winkler, C.): Early childhood gut microbiomes show strong
geographic differences among subjects at high risk for type 1 diabetes. Diabetes Care 38, 329-332 (2015)
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517-518 (2014)
Much, D.°, Beyerlein, A.°, Roßbauer, M.°, Hummel, S.°, Ziegler, A.-G.°: Beneficial effects of breastfeeding
in women with gestational diabetes mellitus. Mol. Metab. 3, 284-292 (2014)
Raab, J., Giannopoulou, E.Z., Schneider, S., Warncke, K., Krasmann, M., Winkler, C., Ziegler, A.-G.°:
Prevalence of vitamin D deficiency in pre-type 1 diabetes and its association with disease progression.
Diabetologia 57, 902-908 (2014)
Warncke, K.°, Engelsberger, I.: Erschwerte Differenzialdiagnose bei einem 17-jährigen Patienten :
Typ-1-Diabetes? Typ-2-Diabetes? Oder „Doppel-Diabetes“? Dtsch. Med. Wochenschr. 139, 1097-1099
(2014)
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Warncke, K.°, Dressel, P., Ziegler, A.-G., Steinborn, M., Bonfig, W., Burdach, S., Engelsberger, I.: Severe
pretreatment cerebral edema in newly diagnosed type 1 diabetes. Horm. Res. Paediatr. 81, 285-288 (2014)
Weber, K.S.C., Raab, J., Haupt, F., Aschemeier, B., Wosch, A., Ried, C., Kordonouri, O., Ziegler, A.-G.,
Winkler, C.°: Evaluating the diet of children at increased risk for type 1 diabetes: First results from the
TEENDIAB study. Public Health Nutr. 18, 50-58 (2015) [published online 2014]
#
#
Winkler, C. , Krumsiek, J. , Buettner, F., Angermüller, C., Giannopoulou, E.Z., Theis, F.J., Ziegler,
page 70 of 247
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Institute of Epidemiology I
Adam, M., Schikowski, T., Carsin, A.E., Cai, Y., Jacquemin, B., Sanchez, M., Vierkötter, A., Marcon, A.,
Keidel, D., Sugiri, D., Al Kanani, Z., Nadif, R., Siroux, V., Hardy, R., Kuh, D., Rochat, T., Bridevaux, P.O.,
Eeftens, M., Tsai, M.Y., Villani, S., Phuleria, H.C., Birk, M., Cyrys, J., Cirach, M., de Nazelle, A.,
Nieuwenhuijsen, M.J., Forsberg, B., de Hoogh, K., Declerq, C., Bono, R., Piccioni, P., Quass, U., Heinrich,
J., Jarvis, D., Pin, I., Beelen, R., Hoek, G., Brunekreef, B., Schindler, C., Sunyer, J., Krämer, U., Kauffmann,
F., Hansell, A.L., Künzli, N., Probst-Hensch, N.°: Adult lung function and long-term air pollution exposure.
ESCAPE: A multicentre cohort study and meta-analysis. Eur. Respir. J. 45, 38-50 (2015) [published online
2014]
Amaral, A.F.°, Ramasamy, A., Castro-Giner, F., Minelli, C., Accordini, S., Sørheim, I.C., Pin, I., Kogevinas,
M., Jõgi, R., Balding, D.J., Norbäck, D., Verlato, G., Olivieri, M., Probst-Hensch, N., Janson, C., Zock, J.P.,
Heinrich, J., Jarvis, D.L.: Interaction between gas cooking and GSTM1 null genotype in bronchial
responsiveness: Results from the European Community Respiratory Health Survey. Thorax 69, 558-564
(2014)
Babisch, W.°, Wolf, K., Petz, M., Heinrich, J., Cyrys, J., Peters, A.°: Associations between traffic noise,
particulate air pollution, hypertension, and isolated systolic hypertension in adults: The KORA study. Environ.
Health Perspect. 122, 492-498 (2014)
Babisch, W.°, Wölke, G., Heinrich, J., Straff, W.: Road traffic noise and hypertension - accounting for the
location of rooms. Environ. Res. 133, 380-387 (2014)
Bakolis, I.°, Heinrich, J., Zock, J.P., Norbäck, D., Svanes, C., Chen, C.M., Accordini, S., Verlato, G.E.,
Olivieri, M., Jarvis, D.L.: House dust-mite allergen exposure is associated with serum specific IgE but not
with respiratory outcomes. Indoor Air 25, 235-244 (2015) [published online 2014]
Beelen, R.°, Stafoggia, M., Raaschou-Nielsen, O., Andersen, Z.J., Xun, W.W., Katsouyanni, K.,
Dimakopoulou, K., Brunekreef, B., Weinmayr, G., Hoffmann, B., Wolf, K., Samoli, E., Houthuijs, D.,
Nieuwenhuijsen, M., Oudin, A., Forsberg, B., Olsson, D., Salomaa, V., Lanki, T., Yli-Tuomi, T., Oftedal, B.,
Aamodt, G., Nafstad, P., de Faire, U., Pedersen, N.L., Ostenson, C.G., Fratiglioni, L., Penell, J., Korek, M.,
Pyko, A., Eriksen, K.T., Tjønneland, A., Becker, T., Eeftens, M., Bots, M.L., Meliefste, K., Wang, M.,
Bueno-de-Mesquita, B., Sugiri, D., Krämer, U., Heinrich, J., de Hoogh, K., Key, T., Peters, A., Cyrys, J.,
Concin, H., Nagel, G., Ineichen, A., Schaffner, E., Probst-Hensch, N., Dratva, J., Ducret-Stich, R., Vilier, A.,
Clavel-Chapelon, F., Stempfelet, M., Grioni, S., Krogh, V., Tsai, M.Y., Marcon, A., Ricceri, F., Sacerdote, C.,
Galassi, C., Migliore, E., Ranzi, A., Cesaroni, G., Badaloni, C., Forastiere, F., Tamayo, I., Amiano, P.,
Dorronsoro, M., Katsoulis, M., Trichopoulou, A., Vineis, P., Hoek, G.: Long-term exposure to air pollution and
cardiovascular mortality : An analysis of 22 European cohorts. Epidemiology 25, 368-378 (2014)
Beyerlein, A., Thiering, E., Pflueger, M., Bidlingmaier, M., Stock, J., Knopff, A., Winkler, C., Heinrich, J.,
Ziegler, A.-G.°: Early infant growth is associated with the risk of islet autoimmunity in genetically susceptible
children. Pediatr. Diabetes 15, 534-542 (2014)
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joint first authors
Bousquet, J., Gern, J.E., Martinez, F.D., Antò, J.M., Johnson, C.C., Holt, P.G., Lemanske Jr., R.F., Le Souëf,
P.N., Tepper, R.S., von Mutius, E., Arshad, S.H., Bacharier, L.B., Becker, A., Belanger, K., Bergström, A.,
Bernstein, D.I., Cabana, M.D., Carroll, K.N., Castro, M., Cooper, P.J., Gillman, M.W., Gold, D.R., Henderson,
J., Heinrich, J., Hong, S.-J., Jackson, D.J., Keil, T., Kozyrskyj, A.L., Carlsen, K.L., Miller, R.L., Momas, I.,
Morgan, W.J., Noel, P., Ownby, D.R., Pinart, M., Ryan, P.H., Schwaninger, J.M., Sears, M.R., Simpson, A.,
Smit, H.A., Stern, D.A., Subbarao, P., Valenta, R., Wang, X., Weiss, S.T., Wood, R.D., Wright, A.L., Wright,
R.J., Togias, A., Gergen, P.J.°: Birth cohorts in asthma and allergic diseases: Report of a
NIAID/NHLBI/MeDALL joint workshop. J. Allergy Clin. Immunol. 133, 1535-1546 (2014)
Bousquet, J., Addis, A., Adcock, I., Agache, I., Agusti, A., Alonso, A., Annesi-Maesano, I., Antò, J.M.,
Bachert, C., Baena-Cagnani, C.E., Bai, C., Baigenzhin, A., Barbara, C., Barnes, P.J., Bateman, E.D., Beck,
L., Bedbrook, A.°, Bel, E.H., Benezet, O., Bennoor, K.S., Benson, M., Bernabeu-Wittel, M., Bewick, M.,
Bindslev-Jensen, C., Blain, H., Blasi, F., Bonini, M., Bonini, S., Boulet, L.P., Bourdin, A., Bourret, R.,
Bousquet, P.J., Brightling, C.E., Briggs, A., Brozek, J.L., Buhl, R., Bush, A., Caimmi, D., Calderon, M.,
Calverley, P., Camargos, P.A.M., Camuzat, T., Canonica, G.W., Carlsen, K.H., Casale, T.B., Cazzola, M.,
Cepeda Sarabia, A.M., Cesario, A., Chen, Y.Z., Chkhartishvili, E., Chavannes, N.H., Chiron, R., Chuchalin,
A., Chung, K.F., Cox, L., Crooks, G., Crooks, M.G., Cruz, A.A., Custovic, A., Dahl, R., Dahlen, S.E., de Blay,
F., Dedeu, T., Deleanu, D., Demoly, P., Devillier, P., Didier, A., Dinh-Xuan, A.T., Djukanovic, R., Dokic, D.,
Douagui, H., Dubakiene, R., Eglin, S., Elliot, F., Emuzyte, R., Fabbri, L., Fink Wagner, A., Fletcher, M.,
Fokkens, W.J., Fonseca, J., Franco, A., Frith, P., Furber, A., Gaga, M., Garcés, J., Garcia-Aymerich, J.,
Gamkrelidze, A., Gonzales-Diaz, S., Gouzi, F., Guzman, M.A., Haahtela, T., Harrison, D., Hayot, M.,
Heaney, L.G., Heinrich, J., Hellings, P.W., Hooper, J., Humbert, M., Hyland, M., Iaccarino, G., Jakovenko,
D., Jardim, J.R., Jeandel, C., Jenkins, C., Johnston, S.L., Jonquet, O., Joos, G., Jung, K.S., Kalayci, O.,
Karunanithi, S., Keil, T., Khaltaev, N., Kolek, V., Kowalski, M.L., Kull, I., Kuna, P., Kvedariene, V., Le, L.T.,
Lodrup Carlsen, K.C., Louis, R., MacNee, W., Mair, A., Majer, I., Manning, P., de Manuel Keenoy, E.,
Masjedi, M.R., Melén, E., Melo-Gomes, E., Menzies-Gow, A., Mercier, G., Mercier, J., Michel, J.P., Miculinic,
N., Mihaltan, F., Milenkovic, B., Molimard, M., Momas, I., Montilla-Santana, A., Morais-Almeida, M., Morgan,
M., N'Diaye, M., Nafti, S., Nekam, K., Neou, A., Nicod, L.P., O'Hehir, R.E., Ohta, K., Paggiaro, P., Palkonen,
S., Palmer, S., Papadopoulos, N.G., Papi, A., Passalacqua, G., Pavord, I.D., Pigearias, B., Plavec, D.,
Postma, D.S., Price, D., Rabe, K.F., Radier Pontal, F., Redon, J., Rennard, S., Roberts, J., Robine, J.M.,
Roca, J., Roche, N., Rodenas, F., Roggeri, A., Rolland, C., Rosado-Pinto, J., Ryan, D., Samolinski, B.,
Sanchez-Borges, M., Schünemann, H.J., Sheikh, A., Shields, M., Siafakas, N.M., Sibille, Y., Similowski, T.,
Small, I., Sola-Morales, O., Sooronbaev, T., Stelmach, R., Sterk, P.J., Stiris, T., Sud, P., Tellier, V., To, T.,
Todo-Bom, A., Triggiani, M., Valenta, R., Valero, A.L., Valiulis, A., Valovirta, E., van Ganse, E., Vandenplas,
O., Vasankari, T., Vestbo, J., Vezzani, G., Viegi, G., Visier, L., Vogelmeier, C., Vontetsianos, T., Wagstaff,
R., Wahn, U., Wallaert, B., Whalley, B., Wickman, M., Williams, D.M., Wilson, N., Yawn, B.P., Yiallouros,
P.K., Yorgancioglu, A., Yusuf, O.M., Zar, H.J., Zhong, N., Zidarn, M., Zuberbier, T.: Integrated care pathways
for airway diseases (AIRWAYS-ICPs). Eur. Respir. J. 44, 304-323 (2014)
Brüske, I.°, Flexeder, C., Heinrich, J.: Body mass index and the incidence of asthma in children. Curr.
Opin. Allergy Clin. Immunol. 14, 155-160 (2014)
page 72 of 247
2015-11-23
#
joint first authors
Brüske, I.°, Thiering, E., Heinrich, J., Huster, K.M., Nowak, D.: Respirable quartz dust exposure and
airway obstruction: A systematic review and meta-analysis. Occup. Environ. Med. 71, 583-589 (2014)
Cai, Y.#, Schikowski, T.#, Adam, M.#, Buschka, A., Carsin, A.E., Jacquemin, B., Marcon, A., Sanchez, M.,
Vierkötter, A., Al-Kanaani, Z., Beelen, R., Birk, M., Brunekreef, B., Cirach, M., Clavel-Chapelon, F.,
Declercq, C., de Hoogh, K., de Nazelle, A., Ducret-Stich, R.E., Ferretti, V., Forsberg, B., Gerbase, M.W.,
Hardy, R., Heinrich, J., Hoek, G., Jarvis, D., Keidel, D., Kuh, D., Nieuwenhuijsen, M.J., Ragettli, M.S., Ranzi,
A., Rochat, T., Schindler, C., Sugiri, D., Temam, S., Tsai, M.Y., Varraso, R., Kauffmann, F., Krämer, U.,
Sunyer, J., Künzli, N., Probst-Hensch, N., Hansell, A.L.°: Cross-sectional associations between air pollution
and chronic bronchitis: An ESCAPE meta-analysis across five cohorts. Thorax 69, 1005-1014 (2014)
Cheelo, M., Lodge, C.J., Dharmage, S.C., Simpson, J.A., Matheson, M.C., Heinrich, J., Lowe, A.J.°:
Paracetamol exposure in pregnancy and early childhood and development of childhood asthma: A
systematic review and meta-analysis. Arch. Dis. Childhood 100, 81-89 (2015) [published online 2014]
Cheng, G., Bolzenius, K., Joslowski, G., Günther, A.L., Kroke, A., Heinrich, J., Buyken, A.E.°: Velocities of
weight, height and fat mass gain during potentially critical periods of growth are decisive for adult body
composition. Eur. J. Clin. Nutr. 69, 262-268 (2015) [published online 2014]
(2014)
Consonni, D.°, De Matteis, S., Pesatori, A.C., Bertazzi, P.A., Olsson, A.C., Kromhout, H., Peters, S.,
Vermeulen, R.C., Pesch, B., Brüning, T., Kendzia, B., Behrens, T., Stücker, I., Guida, F., Wichmann, H.-E.,
Brüske, I., Landi, M.T., Caporaso, N.E., Gustavsson, P., Plato, N., Tse, L.A., Yu, I.T., Jockel, K.H., Ahrens,
W., Pohlabeln, H., Merletti, F., Richiardi, L., Simonato, L., Forastiere, F., Siemiatycki, J., Parent, M., Tardón,
A., Boffetta, P., Zaridze, D., Chen, Y., Field, J.K., 't Mannetje, A., Pearce, N., McLaughlin, J., Demers, P.,
Lissowska, J., Szeszenia-Dabrowska, N., Bencko, V., Foretova, L., Janout, V., Rudnai, P., Fabianova, E.,
Stanescu Dumitru, R., Bueno-de-Mesquita, H.B., Schüz, J., Straif, K.: Lung cancer risk among bricklayers in
a pooled analysis of case-control studies. Int. J. Cancer 136, 360-371 (2015) [published online 2014]
Denholm, R., Schüz, J., Straif, K., Stücker, I., Jockel, K.H., Brenner, D.R., De Matteis, S., Boffetta, P., Guida,
F., Brüske, I., Wichmann, H.-E., Landi, M.T., Caporaso, N., Siemiatycki, J., Ahrens, W., Pohlabeln, H.,
Zaridze, D., Field, J.K., McLaughlin, J., Demers, P., Szeszenia-Dabrowska, N., Lissowska, J., Rudnai, P.,
Fabianova, E., Dumitru, R.S., Bencko, V., Foretova, L., Janout, V., Kendzia, B., Peters, S., Behrens, T.,
Vermeulen, R., Brüning, T., Kromhout, H., Olsson, A.C.°: Is previous respiratory disease a risk factor for lung
cancer? Am. J. Respir. Crit. Care Med. 190, 549-559 (2014)
page 73 of 247
2015-11-23
#
joint first authors
Dias, A.°, Gorzelniak, L., Schultz, K., Wittmann, M., Rudnik, J., Jörres, R.A., Horsch, A.: Classification of
exacerbation episodes in chronic obstructive pulmonary disease patients. Methods Inf. Med. 53, 108-114
(2014)
Diethelm, K., Günther, A.L., Schulze, M.B., Standl, M., Heinrich, J., Buyken, A.E.°: Prospective relevance of
dietary patterns at the beginning and during the course of primary school to the development of body
composition. Br. J. Nutr. 111, 1488-1498 (2014)
Dimakopoulou, K., Samoli, E., Beelen, R., Stafoggia, M., Andersen, Z.J., Hoffmann, B., Fischer, P.,
Nieuwenhuijsen, M., Vineis, P., Xun, W., Hoek, G., Raaschou-Nielsen, O., Oudin, A., Forsberg, B., Modig, L.,
Jousilahti, P., Lanki, T., Turunen, A., Oftedal, B., Nafstad, P., Schwarze, P.E., Penell, J., Fratiglioni, L.,
Andersson, N., Pedersen, N., Korek, M., de Faire, U., Eriksen, K.T., Tjonneland, A., Becker, T., Wang, M.,
Bueno-de-Mesquita, B., Tsai, M., Eeftens, M., Peeters, P.H., Meliefste, K., Marcon, A., Krämer, U.,
Kuhlbusch, T.A.J., Vossoughi, M., Key, T., de Hoogh, K., Hampel, R., Peters, A., Heinrich, J., Weinmayr,
G., Concin, H., Nagel, G., Ineichen, A., Jacquemin, B., Stempfelet, M., Vilier, A., Ricceri, F., Sacerdote, C.,
Pedeli, X., Katsoulis, M., Trichopoulou, A., Brunekreef, B., Katsouyanni, K.°: Air pollution and nonmalignant
respiratory mortality in 16 cohorts within the ESCAPE project. Am. J. Respir. Crit. Care Med. 189, 684-696
(2014)
Durant, J.L.°, Beelen, R., Eeftens, M., Meliefste, K., Cyrys, J., Heinrich, J., Bellander, T., Lewne, M.,
Brunekreef, B., Hoek, G.: Comparison of ambient airborne PM2.5, PM2.5 absorbance and nitrogen dioxide
ratios measured in 1999 and 2009 in three areas in Europe. Sci. Total Environ. 487, 290-298 (2014)
Eeftens, M.°, Hoek, G., Gruzieva, O., Mölter, A., Agius, R.M., Beelen, R., Brunekreef, B., Custovic, A.,
Cyrys, J., Fuertes, E., Heinrich, J., Hoffmann, B., de Hoogh, K., Jedynska, A., Keuken, M., Klümper, C.,
Kooter, I.M., Krämer, U., Korek, M., Koppelman, G.H., Kuhlbusch, T.A.J., Simpson, A., Smit, H.A., Tsai,
M.Y., Wang, M., Wolf, K., Pershagen, G., Gehring, U.: Elemental composition of particulate matter and the
association with lung function. Epidemiology 25, 648-657 (2014)
Fensterer, V.°, Küchenhoff, H., Maier, V., Wichmann, H.-E., Breitner, S., Peters, A., Gu, J., Cyrys, J.:
Evaluation of the impact of low emission zone and heavy traffic ban in Munich (Germany) on the reduction of
PM10 in ambient air. Int. J. Environ. Res. Public Health 11, 5094-5112 (2014)
#
#
Freytag, S. °, Manitz, J. , Schlather, M., Kneib, T., Amos, C.I., Risch, A., Chang-Claude, J., Heinrich, J.,
Bickeböller, H.: A network-based kernel kachine test for the identification of risk pathways in genome-wide
association studies. Hum. Hered. 76, 64-75 (2014)
Fuertes, E., Macintyre, E., Agius, R.M., Beelen, R., Brunekreef, B., Bucci, S., Cesaroni, G., Cirach, M.,
Cyrys, J., Forastiere, F., Gehring, U., Gruzieva, O., Hoffmann, B., Jedynska, A., Keuken, M., Klümper, C.,
Kooter, I.M., Korek, M., Krämer, U., Mölter, A., Nieuwenhuijsen, M., Pershagen, G., Porta, D., Postma, D.S.,
Simpson, A., Smit, H.A., Sugiri, D., Sunyer, J., Wang, M., Heinrich, J.°: Associations between particulate
matter elements and early-life pneumonia in seven birth cohorts: Results from the ESCAPE and
TRANSPHORM projects. Int. J. Hyg. Environ. Health 217, 819-829 (2014)
page 74 of 247
2015-11-23
#
joint first authors
Fuertes, E., Söderhäll, C., Acevedo, N., Becker, A., Brauer, M., Chan-Yeung, M., Dijk, N.F., Heinrich, J., de
Jongste, J., Koppelman, G.H., Postma, D.S., Kere, J., Kozyrskyj, A.L., Pershagen, G., Sandford, A.J.,
Standl, M., Tiesler, C.M., Waldenberger, M., Westman, M., Carlsten, C., Melén, E.°: Associations between
the 17q21 region and allergic rhinitis in 5 birth cohorts. J. Allergy Clin. Immunol. 135, 573-576 (2015)
Fuertes, E.°, Butland, B.K., Anderson, H.R., Carlsten, C., Strachan, D.P., Brauer, M., ISAAC Phase Three
Study Group: Childhood intermittent and persistent rhinitis prevalence and climate and vegetation : A global
ecologic analysis. Ann. Allerg. Asthma Immunol. 113, 386-392 (2014)
Fuertes, E., Markevych, I., von Berg, A., Bauer, C.P., Berdel, D., Koletzko, S., Sugiri, D., Heinrich, J.°:
Greenness and allergies: Evidence of differential associations in two areas in Germany. J. Epidemiol.
Community Health 68, 787-790 (2014)
Gallmeier, K., Becker, E., Kirsten, A., Woelke, G., Manuwald, O., Meyer, H., Magnussen, H., Nowak, D.,
Heinrich, J.°: Prediction of new-onset asthma and nasal allergy by skin prick test and RAST in a cohort of
adults. Eur. Respir. J. 43, 92-102 (2014)
#
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#
#
#
#
#
95, 49-65 (2014)
Ganguly, K.°, Martin, T.M., Concel, V.J., Upadhyay, S., Bein, K., Brant, K.A., George, L., Mitra, A., Thimraj,
T.A., Fabisiak, J.P., Vuga, L.J., Fattman, C., Kaminski, N., Schulz, S., Leikauf, G.D.: Secreted
phosphoprotein 1 is a determinant of lung function development in mice. Am. J. Respir. Cell Mol. Biol. 51,
637-651 (2014)
Gruzieva, O.°, Gehring, U., Aalberse, R., Agius, R.M., Beelen, R., Behrendt, H., Bellander, T., Birk, M., de
Jongste, J.C., Fuertes, E., Heinrich, J., Hoek, G., Klümper, C., Koppelman, G., Korek, M., Krämer, U.,
Lindley, S., Mölter, A., Simpson, A., Standl, M., van Hage, M., von Berg, A., Wijga, A., Brunekreef, B.,
Pershagen, G.: Meta-analysis of air pollution exposure association with allergic sensitization in European
birth cohorts. J. Allergy Clin. Immunol. 133, 767-776 (2014)
page 75 of 247
2015-11-23
#
joint first authors
Guxens, M.°, García-Esteban, R., Giorgis-Allemand, L., Forns, J., Badaloni, C., Ballester, F., Beelen, R.,
Cesaroni, G., Chatzi, L., de Agostini, M., de Nazelle, A., Eeftens, M., Fernández, M.F., Fernández-Somoano,
A., Forastiere, F., Gehring, U., Ghassabian, A., Heude, B., Jaddoe, V.W., Klümper, C., Kogevinas, M.,
Krämer, U., Larroque, B., Lertxundi, A., Lertxuni, N., Murcia, M., Navel, V., Nieuwenhuijsen, M., Porta, D.,
Ramos, R., Roumeliotaki, T., Slama, R., Sørensen, M., Stephanou, E.G., Sugiri, D., Tardón, A., Tiemeier, H.,
Tiesler, C.M., Verhulst, F.C., Vrijkotte, T.G., Wilhelm, M., Brunekreef, B., Pershagen, G., Sunyer, J.: Air
pollution during pregnancy and childhood cognitive and psychomotor development: Six European birth
cohorts. Epidemiology 25, 636-647 (2014)
Heinrich, J.°, Koletzko, B., Koletzko, S.: Timing and diversity of complementary food introduction for
prevention of allergic diseases. How early and how much? Expert Rev. Clin. Immunol. 10, 701-704 (2014)
Hinney, A., Albayrak, Ö., Antel, J., Volckmar, A.L., Sims, R., Chapman, J., Harold, D., Gerrish, A., Heid, I.M.,
Winkler, T.W., Scherag, A., Wiltfang, J., Williams, J., Hebebrand, J.°, GERAD Consortium, IGAP
Consortium, GIANT Consortium (Albrecht, E., Gieger, C., Grallert, H., Heid, I.M., Illig, T.,
Müller-Nurasyid, M., Peters, A., Thorand, B., Wichmann, H.-E.): Genetic variation at the CELF1 (CUGBP,
elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity. Am.
J. Med. Genet. B 165, 283-293 (2014)
Hohmann, C.°, Pinart, M., Tischer, C.G., Gehring, U., Heinrich, J., Kull, I., Melén, E., Smit, H.A., Torrent,
M., Wijga, A.H., Wickman, M., Bachert, C., Lødrup Carlsen, K.C., Carlsen, K.H., Bindslev-Jensen, C., Eller,
E., Esplugues, A., Fantini, M.P., Annesi-Maesano, I., Momas, I., Porta, D., Vassilaki, M., Waiblinger, D.,
Sunyer, J., Antò, J.M., Bousquet, J., Keil, T.°: The development of the MeDALL core questionnaires for a
harmonized follow-up assessment of eleven European birth cohorts on asthma and allergies. Int. Arch.
Allergy Immunol. 163, 215-224 (2014)
Husemann, K.°, Berg, N., Engel, J., Port, J., Joppek, C., Tao, Z., Singer, F., Schulz, S., Kohlhäufl, M.:
Double tracer gas single-breath washout: Reproducibility in healthy subjects and COPD. Eur. Respir. J. 44,
1210-1222 (2014)
I299F
page 76 of 247
2015-11-23
#
joint first authors
Kraja, A.T.°, Chasman, D.I., North, K.E., Reiner, A.P., Yanek, L.R., Kilpeläinen, T.O., Smith, J.A., Dehghan,
A., Dupuis, J., Johnson, A.D., Feitosa, M.F., Tekola-Ayele, F., Chu, A.Y., Nolte, I.M., Dastani, Z., Morris, A.,
Pendergrass, S.A., Sun, Y.V., Ritchie, M.D., Vaez, A., Lin, H., Ligthart, S., Marullo, L., Rohde, R., Shao, Y.,
Ziegler, M.A., Im, H.K., Cross Consortia Pleiotropy (XC-Pleiotropy), CHARGE Consortium, GIANT
Consortium (Albrecht, E., Grallert, H., Thorand, B., Gieger, C., Peters, A., Wichmann, H.-E., Illig, T.,
Müller-Nurasyid, M., Heid, I.M.), Global Lipids Genetics Consortium, MAGIC Consortium, Global BPgen
Consortium (Eyheramendy, S., Döring, A., Meitinger, T., Pfeufer, A.), ADIPOGen Consortium, Women's
Genome Health Study, Howard University Family Study, Schnabel, R.B., Jorgensen, T., Jorgensen, M.E.,
Hansen, T., Pedersen, O., Stolk, R.P., Snieder, H., Hofman, A., Uitterlinden, A.G., Franco, O.H., Ikram, M.A.,
Richards, J.B., Rotimi, C.N., Wilson, J.G., Lange, L.A., Ganesh, S.K., Nalls, M., Rasmussen-Torvik, L.J.,
Pankow, J.S., Coresh, J., Tang, W., Kao, W.H.L., Boerwinkle, E., Morrison, A.C., Ridker, P.M., Becker, D.M.,
Rotter, J.I., Kardia, S.L.R., Loos, R.J.F., Larson, M.G., Hsu, Y.H., Province, M.A., Tracy, R., Voight, B.F.,
Vaidya, D., O'Donnell, C.J., Benjamin, E.J., Alizadeh, B.Z., Prokopenko, I., Meigs, J.B., Borecki, I.B.:
Pleiotropic genes for metabolic syndrome and inflammation. Mol. Genet. Metab. 112, 317-338 (2014)
Kühnisch, J.°, Mach, D., Thiering, E., Brockow, I., Hoffmann, U., Neumann, C., Heinrich-Weltzien, R.,
Bauer, C.P., Berdel, D., von Berg, A., Koletzko, S., Garcia-Godoy, F., Hickel, R., Heinrich, J., GINIplus
Study Group (Chen, C.M., Filipiak, B., Franke, K., Gehring, U., Laubereau, B., Popescu, M.,
Sausenthaler, S., Schoetzau, A., Wichmann, H.-E., Zutavern, A.): Respiratory diseases are associated
with molar-incisor hypomineralizations. Swiss Dent. J. 124, 286-293 (2014)
Liu, C., Fuertes, E., Flexeder, C., Hofbauer, L.C., Berdel, D., Hoffmann, B.H., Kratzsch, J.K., von Berg, A.,
Heinrich, J.°, GINIplus Study Group (Chen, C.M., Filipiak, B., Franke, K., Gehring, U., Laubereau, B.,
Popescu, M., Sausenthaler, S., Schoetzau, A., Wichmann, H.-E., Zutavern, A.), LISAplus Study Group
(Schnappinger, M.): Associations between ambient air pollution and bone turnover markers in 10-year old
children: Results from the GINIplus and LISAplus studies. Int. J. Hyg. Environ. Health 218, 58-65 (2015)
Liu, C.-T.°, Buchkovich, M.L., Winkler, T.W., Heid, I.M., African Ancestry Anthropometry Genetics
Consortium, GIANT Consortium (Albrecht, E., Gieger, C., Grallert, H., Illig, T., Müller-Nurasyid, M.,
Peters, A., Thorand, B., Wichmann, H.-E.), Borecki, I.B., Fox, C.S., Mohlke, K.L., North, K.E., Cupples,
L.A.°: Multi-ethnic fine-mapping of 14 central adiposity loci. Hum. Mol. Genet. 23, 4738-4744 (2014)
page 77 of 247
2015-11-23
#
joint first authors
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Loth, D.W. , Artigas, M.S. , Gharib, S.A. , Wain, L.V. , Franceschini, N. , Koch, B. , Pottinger, T.D. , Smith,
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A.V. , Duan, Q. , Oldmeadow, C., Lee, M.K., Strachan, D.P., James, A.L., Huffman, J.E., Vitart, V.,
Ramasamy, A., Wareham, N.J., Kaprio, J., Wang, X.Q., Trochet, H., Kähönen, M., Flexeder, C., Albrecht,
E., Lopez, L.M., de Jong, K., Thyagarajan, B., Alves, A.C., Enroth, S., Omenaas, E., Joshi, P.K., Fall, T.,
Viñuela, A., Launer, L.J., Loehr, L.R., Fornage, M., Li, G., Wilk, J.B., Tang, W., Manichaikul, A., Lahousse,
L., Harris, T.B., North, K.E., Rudnicka, A.R., Hui, J., Gu, X., Lumley, T., Wright, A.F., Hastie, N.D., Campbell,
S., Kumar, R., Pin, I., Scott, R.A., Pietiläinen, K.H., Surakka, I., Liu, Y., Holliday, E.G., Schulz, S., Heinrich,
J., Davies, G., Vonk, J.M., Wojczynski, M.K., Pouta, A., Johansson, A., Wild, S.H., Ingelsson, E.,
Rivadeneira, F., Völzke, H., Hysi, P.G., Eiriksdottir, G., Morrison, A.C., Rotter, J.I., Gao, W., Postma, D.S.,
White, W.B., Rich, S.S., Hofman, A., Aspelund, T., Couper, D., Smith, L.J., Psaty, B.M., Lohman, K.,
Burchard, E.G., Uitterlinden, A.G., Garcia, M., Joubert, B.R., McArdle, W.L., Musk, A.B., Hansel, N.N.,
Heckbert, S.R., Zgaga, L., van Meurs, J.B., Navarro, P., Rudan, I., Oh, Y.M., Redline, S., Jarvis, D.L., Zhao,
J.H., Rantanen, T., O'Connor, G.T., Ripatti, S., Scott, R.J., Karrasch, S., Grallert, H., Gaddis, N.C., Starr,
J.M., Wijmenga, C., Minster, R.L., Lederer, D.J., Pekkanen, J., Gyllensten, U., Campbell, H., Morris, A.P.,
Gläser, S., Hammond, C.J., Burkart, K.M., Beilby, J., Kritchevsky, S.B., Gudnason, V., Hancock, D.B.,
Williams, O.D., Polasek, O., Zemunik, T., Kolcic, I., Petrini, M.F., Wjst, M., Kim, W.J., Porteous, D.J.,
Scotland, G., Smith, B.H., Viljanen, A., Heliövaara, M., Attia, J.R., Sayers, I., Hampel, R., Gieger, C., Deary,
I.J., Boezen, H.M., Newman, A., Jarvelin, M.R., Wilson, J.F., Lind, L., Stricker, B.H., Teumer, A., Spector,
T.D., Melén, E., Peters, M.J., Lange, L.A., Barr, R.G., Bracke, K.R., Verhamme, F.M., Sung, J., Hiemstra,
P.S., Cassano, P.A., Sood, A., Hayward, C., Dupuis, J., Hall, I.P., Brusselle, G.G., Tobin, M.D.°, London,
S.J.°: Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nat.
Genet. 46, 669-677 (2014)
MacIntyre, E.A., Brauer, M., Melén, E., Bauer, C.P., Bauer, M., Berdel, D., Bergström, A., Brunekreef, B.,
Chan-Yeung, M., Klümper, C., Fuertes, E., Gehring, U., Gref, A., Heinrich, J., Herbarth, O., Kerkhof, M.,
Koppelman, G.H., Kozyrskyj, A.L., Pershagen, G., Postma, D.S., Thiering, E., Tiesler, C.M., Carlsten, C.°:
GSTP1 and TNF gene variants and associations between air pollution and incident childhood asthma: The
Traffic, Asthma and Genetics (TAG) study. Environ. Health Perspect. 122, 418-424 (2014)
MacIntyre, E.A., Gehring, U., Mölter, A., Fuertes, E., Klümper, C., Krämer, U., Quass, U., Hoffmann, B.,
Gascon, M., Brunekreef, B., Koppelman, G.H., Beelen, R., Hoek, G., Birk, M., de Jongste, J.C., Smit, H.A.,
Cyrys, J., Gruzieva, O., Korek, M., Bergström, A., Agius, R.M., de Vocht, F., Simpson, A., Porta, D.,
Forastiere, F., Badaloni, C., Cesaroni, G., Esplugues, A., Fernández-Somoano, A., Lerxundi, A., Sunyer, J.,
Cirach, M., Nieuwenhuijsen, M.J., Pershagen, G., Heinrich, J.°: Air pollution and respiratory infections
during early childhood: An analysis of 10 European birth cohorts within the ESCAPE project. Environ. Health
Perspect. 122, 107-113 (2014)
Malzahn, D.°, Müller-Nurasyid, M., Heid, I.M., Wichmann, H.-E., Bickeböller, H., KORA Study Group
(Gieger, C., Grallert, H., Heinrich, J., Holle, R., Leidl, R., Meisinger, C., Peters, A., Strauch, K.):
Controversial association results for INSIG2 on body mass index may be explained by interactions with age
and with MC4R. Eur. J. Hum. Genet. 22, 1217-1224 (2014)
page 78 of 247
2015-11-23
#
joint first authors
Markevych, I., Thiering, E., Fuertes, E., Sugiri, D., Berdel, D., Koletzko, S., von Berg, A., Bauer, C.P.,
Heinrich, J.°: A cross-sectional analysis of the effects of residential greenness on blood pressure in 10-year
old children: Results from the GINIplus and LISAplus studies. BMC Public Health 14:477 (2014)
Markevych, I., Tiesler, C.M., Fuertes, E., Romanos, M., Dadvand, P., Nieuwenhuijsen, M.J., Berdel, D.,
Koletzko, S., Heinrich, J.°: Access to urban green spaces and behavioural problems in children: Results
from the GINIplus and LISAplus studies. Environ. Int. 71, 29-35 (2014)
Markevych, I., Fuertes, E., Tiesler, C.M., Birk, M., Bauer, C.P., Koletzko, S., von Berg, A., Berdel, D.,
Heinrich, J.°: Surrounding greenness and birth weight: Results from the GINIplus and LISAplus birth cohorts
in Munich. Health Place 26, 39-46 (2013)
Medici, M.#°, Porcu, E.#, Pistis, G.#, Teumer, A., Brown, S.J., Jensen, R.A., Rawal, R., Roef, G.L., Plantinga,
T.S., Vermeulen, S.H., Lahti, J., Simmonds, M.J., Husemoen, L.L., Freathy, R.M., Shields, B.M., Pietzner,
D., Nagy, R., Broer, L., Chaker, L., Korevaar, T.I., Plia, M.G., Sala, C., Völker, U., Richards, J.B., Sweep,
F.C., Gieger, C., Corre, T., Kajantie, E., Thuesen, B., Taes, Y.E., Visser, W.E., Hattersley, A.T., Kratzsch, J.,
Hamilton, A., Li, W., Homuth, G., Lobina, M., Mariotti, S., Soranzo, N., Cocca, M., Nauck, M., Spielhagen, C.,
Ross, A., Arnold, A., van de Bunt, M., Liyanarachchi, S., Heier, M., Grabe, H.J., Masciullo, C., Galesloot,
T.E., Lim, E.M., Reischl, E., Leedman, P.J., Lai, S., Delitala, A., Bremner, A.P., Philips, D.I., Beilby, J.P.,
Mulas, A., Vocale, M., Abecasis, G., Forsen, T., James, A., Widen, E., Hui, J., Prokisch, H., Rietzschel,
E.E., Palotie, A., Feddema, P., Fletcher, S.J., Schramm, K., Rotter, J.I., Kluttig, A., Radke, D., Traglia, M.,
Surdulescu, G.L., He, H., Franklyn, J.A., Tiller, D., Vaidya, B., de Meyer, T., Jørgensen, T., Eriksson, J.G.,
O'Leary, P.C., Wichmann, H.-E., Hermus, A.R., Psaty, B.M., Ittermann, T., Hofman, A., Bosi, E.,
Schlessinger, D., Wallaschofski, H., Pirastu, N., Aulchenko, Y.S., de la Chapelle, A., Netea-Maier, R.T.,
Gough, S.C., Meyer zu Schwabedissen, H.E., Frayling, T.M., Kaufman, J.M., Linneberg, A., Räikkönen, K.,
Smit, J.W.A., Kiemeney, L.A., Rivadeneira, F., Uitterlinden, A.G., Walsh, J.P., Meisinger, C., Den Heijer, M.,
Visser, T.J., Spector, T.D., Wilson, S.G., Völzke, H., Cappola, A., Toniolo, D., Sanna, S., Naitza, S., Peeters,
R.P.: Identification of novel genetic loci associated with thyroid peroxidase antibodies and clinical thyroid
disease. PLoS Genet. 10:e1004123 (2014)
Mölter, A.°, Simpson, A., Berdel, D., Brunekreef, B., Custovic, A., Cyrys, J., de Jongste, J., de Vocht, F.,
Fuertes, E., Gehring, U., Gruzieva, O., Heinrich, J., Hoek, G., Hoffmann, B., Klümper, C., Korek, M.,
Kuhlbusch, T.A.J., Lindley, S., Postma, D., Tischer, C.G., Wijga, A., Pershagen, G., Agius, R.M.: A
multicentre study of air pollution exposure and childhood asthma prevalence: The ESCAPE project. Eur.
Respir. J. 45, 610-624 (2015) [published online 2014]
Moltó-Puigmartí, C.°, van Dongen, M.C., Dagnelie, P.C., Plat, J., Mensink, R.P., Tan, F.E., Heinrich, J.,
Thijs, C.: Maternal but not fetal FADS gene variants modify the association between maternal long-chain
PUFA intake in pregnancy and birth weight. J. Nutr. 144, 1430-1437 (2014)
page 79 of 247
2015-11-23
#
joint first authors
Obayashi, M., Stevanin, G., Synofzik, M., Monin, M.L., Duyckaerts, C., Sato, N., Streichenberger, N.,
Vighetto, A., Desestret, V., Tesson, C., Wichmann, H.-E., Illig, T., Huttenlocher, J., Kita, Y., Izumi, Y.,
Mizusawa, H., Schöls, L., Klopstock, T., Brice, A.°, Ishikawa, K., Durr, A.: Spinocerebellar ataxia type 36
exists in diverse populations and can be caused by a short hexanucleotide GGCCTG repeat expansion. J.
Neurol. Neurosurg. Psychiatr. 86, 986-995 (2015) [published online 2014]
Ortlieb, S., Gorzelniak, L., Nowak, D., Strobl, R., Grill, E., Thorand, B., Peters, A., Kuhn, K.A., Karrasch,
S., Horsch, A., Schulz, H.°: Associations between multiple accelerometry-assessed physical activity
parameters and selected health outcomes in elderly people - results from the KORA-Age study. PLoS ONE
9:e111206 (2014)
Ortlieb, S., Dias, A., Gorzelniak, L., Nowak, D., Karrasch, S., Peters, A., Kuhn, K.A., Horsch, A., Schulz,
S.°: Exploring patterns of accelerometry-assessed physical activity in elderly people. Int. J. Behav. Nutr.
Phys. Act. 11:28 (2014)
Ortlieb, S., Gorzelniak, L., Dias, A., Schulz, S., Horsch, A.°: Recommendations for collecting and
processing accelerometry data in elderly people. Stud. Health Technol. Inform. 192, 1175 (2013)
Park, S.L.°, Fesinmeyer, M.D., Timofeeva, M., Caberto, C.P., Kocarnik, J.M., Han, Y., Love, S.A., Young, A.,
Dumitrescu, L., Lin, Y., Goodloe, R., Wilkens, L.R., Hindorff, L., Fowke, J.H., Carty, C., Buyske, S.,
Schumacher, F.R., Butler, A., Dilks, H., Deelman, E., Cote, M.L., Chen, W., Pande, M., Christiani, D.C.,
Field, J.K., Bickebller, H., Risch, A., Heinrich, J., Brennan, P., Wang, Y., Eisen, T., Houlston, R.S., Thun, M.,
Albanes, D., Caporaso, N., Peters, U., North, K.E., Heiss, G., Crawford, D.C., Bush, W.S., Haiman, C.A.,
Landi, M.T., Hung, R.J., Kooperberg, C., Amos, C.I., Le Marchand, L., Cheng, I.: Pleiotropic associations of
risk variants identified for other cancers with lung cancer risk: The PAGE and TRICL consortia. J. Natl.
Cancer Inst. 106:dju061 (2014)
Pei, Z., Heinrich, J., Fuertes, E., Flexeder, C., Hoffmann, B., Lehmann, I., Schaaf, B., von Berg, A.,
Koletzko, S.°: Cesarean delivery and risk of childhood obesity. J. Pediatr. 164, 1068-1073 (2014)
Pei, Z., Flexeder, C., Fuertes, E., Standl, M., Buyken, A., Berdel, D., von Berg, A., Lehmann, I., Schaaf, B.,
Heinrich, J.°: Food intake and overweight in school-aged children in Germany: Results of the GINIplus and
LISAplus studies. Ann. Nutr. Metab. 64, 60-70 (2014)
Pei, Z., Flexeder, C., Fuertes, E., Standl, M., Berdel, D., von Berg, A., Koletzko, S., Schaaf, B., Heinrich,
J.°, GINIplus Study Group (Chen, C.-M., Filipiak, B., Franke, K., Gehring, U., Laubereau, B., Popescu,
M., Sausenthaler, S., Schoetzau, A., Wichmann, H.-E., Zutavern, A.), LISAplus Study Group: Mother's
body mass index and food intake in school-aged children: Results of the GINIplus and the LISAplus studies.
Eur. J. Clin. Nutr. 68, 898-906 (2014)
page 80 of 247
2015-11-23
#
joint first authors
#
#
Pinart, M. , Benet, M. , Annesi-Maesano, I., von Berg, A., Berdel, D., Carlsen, K.C.L., Carlsen, K.H.,
Bindslev-Jensen, C., Eller, E., Fantini, M.P., Lenzi, J., Gehring, U., Heinrich, J., Hohmann, C., Just, J., Keil,
T., Kerkhof, M., Kogevinas, M., Koletzko, S., Koppelman, G.H., Kull, I., Lau, S., Melén, E., Momas, I., Porta,
D., Postma, D.S., Ranciere, F., Smit, H.A., Stein, R.T., Tischer, C.G., Torrent, M., Wickman, M., Wijga, A.H.,
Bousquet, J., Sunyer, J., Basagana, X., Guerra, S., Garcia-Aymerich, J., Antò, J.M.°: Comorbidity of
eczema, rhinitis, and asthma in IgE-sensitised and non-IgE-sensitised children in MeDALL: A
population-based cohort study. Lancet Resp. Med. 2, 131-140 (2014)
#
#
#
Schikowski, T. °, Adam, M. , Marcon, A. , Cai, Y., Vierkötter, A., Carsin, A.E., Jacquemin, B., Al Kanani, Z.,
Beelen, R., Birk, M., Bridevaux, P.O., Brunekeef, B., Burney, P., Cirach, M., Cyrys, J., de Hoogh, K., de
Marco, R., de Nazelle, A., Declercq, C., Forsberg, B., Hardy, R., Heinrich, J., Hoek, G., Jarvis, D., Keidel,
D., Kuh, D., Kuhlbusch, T., Migliore, E., Mosler, G., Nieuwenhuijsen, M.J., Phuleria, H., Rochat, T.,
Schindler, C., Villani, S., Tsai, M.Y., Zemp, E., Hansell, A., Kauffmann, F., Sunyer, J., Probst-Hensch, N.,
Krämer, U., Künzli, N.: Association of ambient air pollution with the prevalence and incidence of COPD. Eur.
Respir. J. 44, 614-626 (2014)
(2014)
Simpson, C.L., Wojciechowski, R., Oexle, K., Murgia, F., Portas, L., Li, X., Verhoeven, V.J.M., Vitart, V.,
Schache, M., Hosseini, S.M., Hysi, P.G., Raffel, L.J., Cotch, M.F., Chew, E., Klein, B.E.K., Klein, R., Wong,
T.Y., van Duijn, C.M., Mitchell, P., Saw, S.M., Fossarello, M., Wang, J.J., DCCT/EDIC Research Group,
Polasek, O., Campbell, H., Rudan, I., Oostra, B.A., Uitterlinden, A.G., Hofman, A., Rivadeneira, F., Amin, N.,
Karssen, L.C., Vingerling, J.R., Döring, A., Bettecken, T., Bencic, G., Gieger, C., Wichmann, H.-E.,
Wilson, J.F., Venturini, C., Fleck, B., Cumberland, P.M., Rahi, J.S., Hammond, C.J., Hayward, C., Wright,
A.F., Paterson, A.D., Baird, P.N., Klaver, C.C., Rotter, J.I., Pirastu, M., Meitinger, T., Bailey-Wilson, J.E.°:
Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. PLoS
ONE 9:e107110 (2014)
Standl, M.°, Thiering, E., Demmelmair, H., Koletzko, B., Heinrich, J.: Age-dependent effects of cord blood
long-chain PUFA composition on BMI during the first 10 years of life. Br. J. Nutr. 111, 2024-2031 (2014)
Standl, M.°, Demmelmair, H., Koletzko, B., Heinrich, J.: Cord blood LC-PUFA composition and allergic
diseases during the first 10 yr. Results from the LISAplus study. Pediatr. Allergy Immunol. 35, 344-350
(2014)
page 81 of 247
2015-11-23
#
joint first authors
#
#
#
#
#
#
#
Tang, W. , Kowgier, M. , Loth, D.W. , Soler Artigas, M. , Joubert, B.R. , Hodge, E. , Gharib, S.A. , Smith,
A.V., Ruczinski, I., Gudnason, V., Mathias, R.A., Harris, T.B., Hansel, N.N., Launer, L.J., Barnes, K.C.,
Hansen, J.G., Albrecht, E., Aldrich, M.C., Allerhand, M., Barr, R.G., Brusselle, G.G., Couper, D.J., Curjuric,
I., Davies, G., Deary, I.J., Dupuis, J., Fall, T., Foy, M., Franceschini, N., Gao, W., Gläser, S., Gu, X.,
Hancock, D.B., Heinrich, J., Hofman, A., Imboden, M., Ingelsson, E., James, A., Karrasch, S., Koch, B.,
Kritchevsky, S.B., Kumar, A., Lahousse, L., Li, G., Lind, L., Lindgren, C., Liu, Y., Lohman, K., Lumley, T.,
McArdle, W.L., Meibohm, B., Morris, A.P., Morrison, A.C., Musk, B., North, K.E., Palmer, L.J.,
Probst-Hensch, N.M., Psaty, B.M., Rivadeneira, F., Rotter, J.I., Schulz, S., Smith, L.J., Sood, A., Starr, J.M.,
Strachan, D.P., Teumer, A., Uitterlinden, A.G., Völzke, H., Voorman, A., Wain, L.V., Wells, M.T., Wilk, J.B.,
Williams, O.D., Heckbert, S.R., Stricker, B.H., London, S.J., Fornage, M., Tobin, M.D., O'Connor, G.T., Hall,
I.P., Cassano, P.A.°: Large-scale genome-wide association studies and meta-analyses of longitudinal
change in adult lung function. PLoS ONE 9:e100776 (2014)
Thaler-Kall, K.°, Döring, A., Peters, A., Thorand, B., Grill, E., Koenig, W., Horsch, A., Meisinger, C.:
Association between anemia and falls in community-dwelling older people: Cross-sectional results from the
KORA-Age study. BMC Geriatr. 14:29 (2014)
Tiesler, C.M.°, Heinrich, J.: Prenatal nicotine exposure and child behavioural problems. Eur. Child Adolesc.
Psych. 23, 913-929 (2014)
Tischer, C.G.°, Casas, L., Wouters, I.M., Doekes, G., García-Esteban, R., Gehring, U., Hyvärinen, A.,
Oldenwening, M., Kerkhof, M., Sunyer, J., Standl, M., Thiering, E., Torrent, M., Heinrich, J., HITEA Study
Group: Early exposure to bio-contaminants and asthma up to 10 years of age: Results of the HITEA study.
Eur. Respir. J. 54, 328-337 (2015) [published online 2014]
Upadhyay, S.°, Stöger, T., George, L., Schladweiler, M.C., Kodavanti, U.P., Ganguly, K., Schulz, H.°:
Ultrafine carbon particle mediated cardiovascular impairment of aged spontaneously hypertensive rats. Part.
Fibre Toxicol. 11:36 (2014)
page 82 of 247
2015-11-23
#
joint first authors
#
#
#
#
#
van der Valk, R.J. , Kreiner-Møller, E. , Kooijman, M.N. , Guxens, M. , Stergiakouli, E. , Saaf, A., Bradfield,
J.P., Geller, F., Hayes, M.G., Cousminer, D.L., Körner, A., Thiering, E., Curtin, J.A., Myhre, R., Huikari, V.,
Joro, R., Kerkhof, M., Warrington, N.M., Pitkänen, N., Ntalla, I., Horikoshi, M., Veijola, R., Freathy, R.M., Teo,
Y.Y., Barton, S.J., Evans, D.M., Kemp, J.P., St Pourcain, B., Ring, S.M., Smith, G.D., Bergström, A., Kull, I.,
Hakonarson, H., Mentch, F.D., Bisgaard, H., Chawes, B., Stokholm, J., Waage, J., Eriksen, P., Sevelsted, A.,
Melbye, M., van Duijn, C.M., Medina-Gomez, C., Hofman, A., de Jongste, J.C., Taal, H.R., Uitterlinden, A.G.,
Armstrong, L.L., Eriksson, J., Palotie, A., Bustamante, M., Estivill, X., Gonzalez, J.R., Llop, S., Kiess, W.,
Mahajan, A., Flexeder, C., Tiesler, C.M., Murray, C.S., Simpson, A., Magnus, P., Sengpiel, V., Hartikainen,
A.L., Keinanen-Kiukaanniemi, S., Lewin, A., da Silva Couto Alves, A., Blakemore, A.I., Buxton, J.L.,
Kaakinen, M., Rodriguez, A., Sebert, S., Vaarasmaki, M., Lakka, T., Lindi, V., Gehring, U., Postma, D.S.,
Ang, W., Newnham, J.P., Lyytikäinen, L.P., Pahkala, K., Raitakari, O.T., Panoutsopoulou, K., Zeggini, E.,
Boomsma, D.I., Groen-Blokhuis, M., Ilonen, J., Franke, L., Hirschhorn, J.N., Pers, T.H., Liang, L., Huang, J.,
Hocher, B., Knip, M., Saw, S.M., Holloway, J.W., Melén, E., Grant, S.F., Feenstra, B., Lowe, W.L., Widen, E.,
Sergeyev, E., Grallert, H., Custovic, A., Jacobsson, B., Jarvelin, M.R., Atalay, M., Koppelman, G.H., Pennell,
C.E., Niinikoski, H., Dedoussis, G.V., McCarthy, M.I., Frayling, T.M., Sunyer, J., Timpson, N.J., Rivadeneira,
F., Bønnelykke, K., Jaddoe, V.W.°: A novel common variant in DCST2 is associated with length in early life
and height in adulthood. Hum. Mol. Genet. 24, 1155-1168 (2015) [published online 2014]
Vimaleswaran, K.S.#°, Cavadino, A.#°, Berry, D.J., Jorde, R., Dieffenbach, A.K., Lu, C., Alves, A.C.,
Heerspink, H.J., Tikkanen, E., Eriksson, J., Wong, A., Mangino, M., Jablonski, K.A., Nolte, I.M., Houston,
D.K., Ahluwalia, T.S., van der Most, P.J., Pasko, D., Zgaga, L., Thiering, E., Vitart, V., Fraser, R.M.,
Huffman, J.E., de Boer, R.A., Schöttker, B., Saum, K.U., McCarthy, M.I., Dupuis, J., Herzig, K.H., Sebert, S.,
Pouta, A., Laitinen, J., Kleber, M.E., Navis, G., Lorentzon, M., Jameson, K., Arden, N., Cooper, J.A.,
Acharya, J., Hardy, R., Raitakari, O., Ripatti, S., Billings, L.K., Lahti, J., Osmond, C., Penninx, B.W.,
Rejnmark, L., Lohman, K.K., Paternoster, L., Stolk, R.P., Hernandez, D.G., Byberg, L., Hagström, E.,
Melhus, H., Ingelsson, E., Mellström, D., Ljunggren, O., Tzoulaki, I., McLachlan, S., Theodoratou, E.,
Tiesler, C.M., Jula, A., Navarro, P., Wright, A.F., Polasek, O., ICBP Consortium, CHARGE Consortium,
Global BPgen Consortium, Wilson, J.F., Rudan, I., Salomaa, V., Heinrich, J., Campbell, H., Price, J.F.,
Karlsson, M., Lind, L., Michaelsson, K., Bandinelli, S., Frayling, T.M., Hartman, C.A., Sørensen, T.I.,
Kritchevsky, S.B., Langdahl, B.L., Eriksson, J.G., Florez, J.C., Spector, T.D., Lehtimäki, T., Kuh, D.,
Humphries, S.E., Cooper, C., Ohlsson, C., Marz, W., de Borst, M.H., Kumari, M., Kivimaki, M., Wang, T.J.,
Power, C., Brenner, H., Grimnes, G., van der Harst, P., Snieder, H., Hingorani, A.D., Pilz, S., Whittaker, J.C.,
Jarvelin, M.R., Hyppönen, E.°: Association of vitamin D status with arterial blood pressure and hypertension
risk: A mendelian randomisation study. Lancet Diabet. Endocrinol. 2, 719-729 (2014)
page 83 of 247
2015-11-23
#
joint first authors
Vlaanderen, J.°, Portengen, L., Schüz, J., Olsson, A., Pesch, B., Kendzia, B., Stücker, I., Guida, F., Brüske,
I., Wichmann, H.-E., Consonni, D., Landi, M.T., Caporaso, N., Siemiatycki, J., Merletti, F., Mirabelli, D.,
Richiardi, L., Gustavsson, P., Plato, N., Jöckel, K.-H., Ahrens, W., Pohlabeln, H., Tardón, A., Zaridze, D.,
Field, J.K., 't Mannetje, A., Pearce, N., McLaughlin, J., Demers, P., Szeszenia-Dabrowska, N., Lissowska, J.,
Rudnai, P., Fabianova, E., Dumitru, R.S., Bencko, V., Foretova, L., Janout, V., Boffetta, P., Forastiere, F.,
Bueno-de-Mesquita, B., Peters, S., Brüning, T., Kromhout, H., Straif, K., Vermeulen, R.: Effect modification
of the association of cumulative exposure and cancer risk by intensity of exposure and time since exposure
cessation: A flexible method applied to cigarette smoking and lung cancer in the SYNERGY study. Am. J.
Epidemiol. 179, 290-298 (2014)
Wang, M.°, Beelen, R., Stafoggia, M., Raaschou-Nielsen, O., Andersen, Z.J., Hoffmann, B., Fischer, P.,
Houthuijs, D., Nieuwenhuijsen, M., Weinmayr, G., Vineis, P., Xun, W.W., Dimakopoulou, K., Samoli, E.,
Laatikainen, T., Lanki, T., Turunen, A.W., Oftedal, B., Schwarze, P., Aamodt, G., Penell, J., de Faire, U.,
Korek, M., Leander, K., Pershagen, G., Pedersen, N.L., Ostenson, C.G., Fratiglioni, L., Eriksen, K.T.,
Sørensen, M., Tjønneland, A., Bueno-de-Mesquita, B., Eeftens, M., Bots, M.L., Meliefste, K., Krämer, U.,
Heinrich, J., Sugiri, D., Key, T., de Hoogh, K., Wolf, K., Peters, A., Cyrys, J., Jaensch, A., Concin, H.,
Nagel, G., Tsai, M.Y., Phuleria, H., Ineichen, A., Künzli, N., Probst-Hensch, N., Schaffner, E., Vilier, A.,
Clavel-Chapelon, F., Declerq, C., Ricceri, F., Sacerdote, C., Marcon, A., Galassi, C., Migliore, E., Ranzi, A.,
Cesaroni, G., Badaloni, C., Forastiere, F., Katsoulis, M., Trichopoulou, A., Keuken, M., Jedynska, A., Kooter,
I.M., Kukkonen, J.V.K., Sokhi, R.S., Brunekreef, B., Katsouyanni, K., Hoek, G.: Long-term exposure to
elemental constituents of particulate matter and cardiovascular mortality in 19 European cohorts: Results
from the ESCAPE and TRANSPHORM projects. Environ. Int. 66, 97-106 (2014)
Wang, M.°, Beelen, R., Bellander, T., Birk, M., Cesaroni, G., Cirach, M., Cyrys, J., de Hoogh, K., Declercq,
C., Dimakopoulou, K., Eeftens, M., Eriksen, K.T., Forastiere, F., Galassi, C., Grivas, G., Heinrich, J.,
Hoffmann, B., Ineichen, A., Korek, M., Lanki, T., Lindley, S., Modig, L., Mölter, A., Nafstad, P.,
Nieuwenhuijsen, M.J., Nystad, W., Olsson, D., Raaschou-Nielsen, O., Ragettli, M., Ranzi, A., Stempfelet, M.,
Sugiri, D., Tsai, M.Y., Udvardy, O., Varró, M.J., Vienneau, D., Weinmayr, G., Wolf, K., Yli-Tuomi, T., Hoek,
G., Brunekreef, B.: Performance of multi-city land use regression models for nitrogen dioxide and fine
particles. Environ. Health Perspect. 122, 843-849 (2014)
Wawro, N., Heinrich, J., Thiering, E., Kratzsch, J., Schaaf, B., Hoffmann, B., Lehmann, I., Bauer, C.P.,
Koletzko, S., von Berg, A., Berdel, D., Linseisen, J.°: Serum 25(OH)D concentrations and atopic diseases at
age 10: Results from the GINIplus and LISAplus birth cohort studies. BMC Pediatr. 14:286 (2014)
Winkler, V.°, Leitzmann, M., Obi, N., Ahrens, W., Edinger, T., Giani, G., Linseisen, J., Löffler, M., Michels,
K., Nöthlings, U., Schipf, S., Kluttig, A., Wichmann, H.-E., Hoffmann, B., Jockel, K.H., Becher, H.: Response
in individuals with and without foreign background and application to the National Cohort in Germany: Which
factors have an effect? Int. J. Public Health 59, 555-563 (2014)
page 84 of 247
2015-11-23
#
joint first authors
Wood, A.R., Esko, T., Yang, J., Vedantam, S., Pers, T.H., Gustafsson, S., Chu, A.Y., Estrada, K., Luan, J.,
Kutalik, Z., Amin, N., Buchkovich, M.L., Croteau-Chonka, D.C., Day, F.R., Duan, Y., Fall, T., Fehrmann,
R.S.N., Ferreira, T., Jackson, A.U., Karjalainen, J., Lo, K.S., Locke, A.E., Mägi, R., Mihailov, E., Porcu, E.,
Randall, J.C., Scherag, A., Vinkhuyzen, A.A., Westra, H.J., Winkler, T.W., Workalemahu, T., Zhao, J.H.,
Absher, D., Albrecht, E., Anderson, D., Baron, J.A., Beekman, M., Demirkan, A., Ehret, G.B., Feenstra, B.,
Feitosa, M.F., Fischer, K., Fraser, R.M., Goel, A., Gong, J., Justice, A.E., Kanoni, S., Kleber, M.E.,
Kristiansson, K., Lim, U., Lotay, V., Lui, J.C., Mangino, M., Leach, I.M., Medina-Gomez, C., Nalls, M.A.,
Nyholt, D.R., Palmer, C.D., Pasko, D., Pechlivanis, S., Prokopenko, I., Ried, J.S., Ripke, S., Shungin, D.,
Stancáková, A., Strawbridge, R.J., Sung, Y.J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S.W., van
Setten, J., van Vliet-Ostaptchouk, J.V., Wang, Z., Yengo, L., Zhang, W., Afzal, U., Ärnlöv, J., Arscott, G.M.,
Bandinelli, S., Barrett, A., Bellis, C., Bennett, A.J., Berne, C., Blüher, M., Bolton, J.L., Böttcher, Y., Boyd,
H.A., Bruinenberg, M., Buckley, B.M., Buyske, S., Caspersen, I.H., Chines, P.S., Clarke, R., Claudi-Boehm,
S., Cooper, M.N., Daw, E.W., De Jong, P.A., Deelen, J., Delgado, G., Denny, J.C., Dhonukshe-Rutten, R.,
Dimitriou, M., Doney, A.S., Dörr, M., Eklund, N., Eury, E., Folkersen, L., Garcia, M.E., Geller, F., Giedraitis,
V., Go, A.S., Grallert, H., Grammer, T.B., Gräßler, J., Grönberg, H., de Groot, L.C., Groves, C.J., Haessler,
J., Hall, P., Haller, T., Hallmans, G., Hannemann, A., Hartman, C.A., Hassinen, M., Hayward, C.,
Heard-Costa, N.L., Helmer, Q., Hemani, G., Henders, A.K., Hillege, H.L., Hlatky, M.A., Hoffmann, W.,
Hoffmann, P., Holmen, O.L., Houwing-Duistermaat, J.J., Illig, T., Isaacs, A., James, A.L., Jeff, J., Johansen,
B., Johansson, A., Jolley, J., Juliusdottir, T., Junttila, J., Kho, A.N., Kinnunen, L., Klopp, N., Kocher, T.,
Kratzer, W., Lichtner, P., Lind, L., Lindstrom, J., Lobbens, S., Lorentzon, M., Lu, Y., Lyssenko, V.,
Magnusson, P.K., Mahajan, A., Maillard, M., McArdle, W.L., McKenzie, C.A., McLachlan, S., McLaren, P.J.,
Menni, C., Merger, S., Milani, L., Moayyeri, A., Monda, K.L., Morken, M.A., Müller, G., Müller-Nurasyid, M.,
Musk, A.W., Narisu, N., Nauck, M., Nolte, I.M., Nöthen, M.M., Oozageer, L., Pilz, S., Rayner, N.W.,
Renström, F., Robertson, N.R., Rose, L.M., Roussel, R., Sanna, S., Scharnagl, H., Scholtens, S.,
Schumacher, F.R., Schunkert, H., Scott, R.A., Sehmi, J., Seufferlein, T., Shi, J., Silventoinen, K., Smit, J.H.,
Smith, A.V., Smolonska, J., Stanton, A.V., Stirrups, K., Stott, D.J., Stringham, H.M., Sundström, J., Swertz,
M.A., Syvanen, A.C., Tayo, B.O., Thorleifsson, G., Tyrer, J.P., van Dijk, S., van Schoor, N.M., van der Velde,
N., van Heemst, D., van Oort, F.V., Vermeulen, S.H., Verweij, N., Vonk, J.M., Waite, L.L., Waldenberger,
M., Wennauer, R., Wilkens, L.R., Willenborg, C., Wilsgaard, T., Wojczynski, M.K., Wong, A., Wright, A.F.,
Zhang, Q., Arveiler, D., Bakker, S.J., Beilby, J., Bergman, R.N., Bergmann, S., Biffar, R., Blangero, J.,
Boomsma, D.I., Bornstein, S.R., Bovet, P., Brambilla, P., Brown, M.J., Campbell, H., Caulfield, M.J.,
Chakravarti, A., Collins, R., Collins, F.S., Crawford, D.C., Cupples, L.A., Danesh, J., de Faire, U., den Ruijter,
H.M., Erbel, R., Erdmann, J., Eriksson, J.G., Farrall, M., Ferrannini, E., Ferrieres, J., Ford, I., Forouhi, N.G.,
Forrester, T., Gansevoort, R.T., Gejman, P.V., Gieger, C., Golay, A., Gottesman, O., Gudnason, V.,
Gyllensten, U., Haas, D.W., Hall, A.S., Harris, T.B., Hattersley, A.T., Heath, A.C., Hengstenberg, C., Hicks,
A.A., Hindorff, L.A., Hingorani, A.D., Hofman, A., Hovingh, G.K., Humphries, S.E., Hunt, S.C., Hyppönen, E.,
Jacobs, K.B., Jarvelin, M.R., Jousilahti, P., Jula, A.M., Kaprio, J., Kastelein, J.J., Kayser, M., Kee, F.,
Keinanen-Kiukaanniemi, S.M., Kiemeney, L.A., Kooner, J.S., Kooperberg, C., Koskinen, S., Kovacs, P.,
Kraja, A.T., Kumari, M., Kuusisto, J., Lakka, T.A., Langenberg, C., Le Marchand, L., Lehtimäki, T., Lupoli, S.,
Madden, P.A., Männisto, S., Manunta, P., Marette, A., Matise, T.C., McKnight, B., Meitinger, T., Moll, F.L.,
Montgomery, G.W., Morris, A.D., Morris, A.P., Murray, J.C., Nelis, M., Ohlsson, C., Oldehinkel, A.J., Ong,
K.K., Ouwehand, W.H., Pasterkamp, G., Peters, A., Pramstaller, P.P., Price, J.F., Qi, L., Raitakari, O.T.,
page 85 of 247
2015-11-23
#
joint first authors
Rankinen, T., Rao, D.C., Rice, T.K., Ritchie, M.D., Rudan, I., Salomaa, V., Samani, N.J., Saramies, J.,
Sarzynski, M.A., Schwarz, P.E., Sebert, S., Sever, P., Shuldiner, A.R., Sinisalo, J., Steinthorsdottir, V., Stolk,
R.P., Tardif, J.C., Tönjes, A., Tremblay, A., Tremoli, E., Virtamo, J., Vohl, M.C., Amouyel, P., Asselbergs,
F.W., Assimes, T.L., Bochud, M., Boehm, B.O., Boerwinkle, E., Bottinger, E.P., Bouchard, C., Cauchi, S.,
Chambers, J.C., Chanock, S.J., Cooper, R.S., de Bakker, P.I., Dedoussis, G., Ferrucci, L., Franks, P.W.,
Froguel, P., Groop, L.C., Haiman, C.A., Hamsten, A., Hayes, M.G., Hui, J., Hunter, D.J., Hveem, K., Jukema,
J.W., Kaplan, R.C., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Martin, N.G., Marz, W., Melbye, M., Moebus,
S., Munroe, P.B., Njølstad, I., Oostra, B.A., Palmer, C.N., Pedersen, N.L., Perola, M., Perusse, L., Peters, U.,
Powell, J.E., Power, C., Quertermous, T., Rauramaa, R., Reinmaa, E., Ridker, P.M., Rivadeneira, F., Rotter,
J.I., Saaristo, T.E., Saleheen, D., Schlessinger, D., Slagboom, P.E., Snieder, H., Spector, T.D., Strauch, K.,
Stumvoll, M., Tuomilehto, J., Uusitupa, M., van der Harst, P., Völzke, H., Walker, M., Wareham, N.J.,
Watkins, H., Wichmann, H.-E., Wilson, J.F., Zanen, P., Deloukas, P., Heid, I.M., Lindgren, C.M., Mohlke,
K.L., Speliotes, E.K., Thorsteinsdottir, U., Barroso, I., Fox, C.S., North, K.E., Strachan, D.P., Beckmann, J.S.,
Berndt, S.I., Boehnke, M., Borecki, I.B., McCarthy, M.I., Metspalu, A., Stefansson, K., Uitterlinden, A.G., van
Duijn, C.M., Franke, L., Willer, C.J., Price, A.L., Lettre, G., Loos, R.J., Weedon, M.N., Ingelsson, E.,
O'Connell, J.R., Abecasis, G.R., Chasman, D.I., Goddard, M.E., Visscher, P.M.°, Hirschhorn, J.N.°, Frayling,
T.M.°: Defining the role of common variation in the genomic and biological architecture of adult human
height. Nat. Genet. 46, 1173-1186 (2014)
Yoneyama, S.#, Guo, Y.#, Lanktree, M.B.#, Barnes, M.R.#, Elbers, C.C., Karczewski, K.J., Padmanabhan, S.,
Bauer, F., Baumert, J.J., Beitelshees, A.L., Berenson, G.S., Boer, J.M., Burke, G.L., Cade, B., Chen, W.,
Cooper-DeHoff, R.M., Gaunt, T.R., Gieger, C., Gong, Y., Gorski, M., Heard-Costa, N., Johnson, T.,
Lamonte, M.J., McDonough, C., Monda, K.L., Onland-Moret, N.C., Nelson, C.P., O'Connell, J.R., Ordovas,
J., Peter, I., Peters, A., Shaffer, J., Shen, H., Smith, E., Speilotes, L., Thomas, F., Thorand, B., Monique
Verschuren, W.M., Anand, S.S., Dominiczak, A., Davidson, K.W., Hegele, R.A., Heid, I.M., Hofker, M.H.,
Huggins, G.S., Illig, T., Johnson, J.A., Kirkland, S.A., Look AHEAD Research Group, König, W., Langaee,
T.Y., McCaffery, J., Melander, O., Mitchell, B.D., Munroe, P., Murray, S.S., Papanicolaou, G.J., Redline, S.,
Reilly, M., Samani, N.J., Schork, N.J., van der Schouw, Y.T., Shimbo, D., Shuldiner, A.R., Tobin, M.D.,
Wijmenga, C., Yusuf, S., GIANT Consortium (Grallert, H., Heinrich, J., Thiering, E., Wichmann, H.-E.),
CARe IBC Consortium, Hakonarson, H., Lange, L.A., Demerath, E.W., Fox, C.S., North, K.E., Reiner, A.P.,
Keating, B.J., Taylor, K.C.°: Gene-centric meta-analyses for central adiposity traits in up to 57412 individuals
of European descent confirm known loci and reveal several novel associations. Hum. Mol. Genet. 23,
2498-2510 (2014)
page 86 of 247
2015-11-23
#
joint first authors
Institute of Epidemiology II
Abbas, S., Linseisen, J.°, Rohrmann, S., Beulens, J.W.J., Buijsse, B., Amiano, P., Ardanaz, E., Balkau, B.,
Boeing, H., Clavel-Chapelon, F., Fagherazzi, G., Franks, P.W., Gavrila, D., Grioni, S., Kaaks, R., Key, T.J.,
Khaw, K.T., Kuhn, T., Mattiello, A., Molina-Montes, E., Nilsson, P.M., Overvad, K., Quirós, J.R., Rolandsson,
O., Sacerdote, C., Saieva, C., Slimani, N., Sluijs, I., Spijkerman, A.M.W., Tjonneland, A., Tumino, R., van der
A, D.L., Zamora-Ros, R., Sharp, S.J., Langenberg, C., Forouhi, N.G., Riboli, E., Wareham, N.J.: Dietary
vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and
Nutrition: The EPIC-InterAct study. Eur. J. Clin. Nutr. 68, 196-202 (2014)
Adam, M., Schikowski, T., Carsin, A.E., Cai, Y., Jacquemin, B., Sanchez, M., Vierkötter, A., Marcon, A.,
Keidel, D., Sugiri, D., Al Kanani, Z., Nadif, R., Siroux, V., Hardy, R., Kuh, D., Rochat, T., Bridevaux, P.O.,
Eeftens, M., Tsai, M.Y., Villani, S., Phuleria, H.C., Birk, M., Cyrys, J., Cirach, M., de Nazelle, A.,
Nieuwenhuijsen, M.J., Forsberg, B., de Hoogh, K., Declerq, C., Bono, R., Piccioni, P., Quass, U., Heinrich,
J., Jarvis, D., Pin, I., Beelen, R., Hoek, G., Brunekreef, B., Schindler, C., Sunyer, J., Krämer, U., Kauffmann,
F., Hansell, A.L., Künzli, N., Probst-Hensch, N.°: Adult lung function and long-term air pollution exposure.
ESCAPE: A multicentre cohort study and meta-analysis. Eur. Respir. J. 45, 38-50 (2015) [published online
2014]
Agarwala, V., Flannick, J., Sunyaev, S.R., GoT2D Consortium (Gieger, C., Grallert, H., Hrabě de Angelis,
M., Huth, C., Kriebel, J., Meisinger, C., Meitinger, T., Müller-Nurasyid, M., Peters, A., Rathmann, W.,
Ried, J.S., Strauch, K., Strom, T.M.), Altshuler, D.°: Evaluating empirical bounds on complex disease
genetic architecture. Nat. Genet. 45, 1418-1427 (2013)
Ahlberg, S., Antonopulos, A., Diendorf, J., Dringen, R., Epple, M.°, Flöck, R., Goedecke, W., Graf, C.,
Haberl, N., Helmlinger, J., Herzog, F., Heuer, F., Hirn, S., Johannes, C., Kittler, S., Köller, M., Korn, K.,
Kreyling, W.G., Krombach, F., Lademann, J., Loza, K., Luther, E.M., Malissek, M., Meinke, M.C.,
Nordmeyer, D., Pailliart, A., Raabe, J., Rancan, F., Rothen-Rutishauser, B., Rühl, E., Schleh, C., Seibel, A.,
Sengstock, C., Treuel, L., Vogt, A., Weber, K., Zellner, R.: PVP-coated, negatively charged silver
nanoparticles: A multi-center study of their physicochemical characteristics, cell culture and in vivo
experiments. Beilstein J. Nanotechnol. 5, 1944-1965 (2014)
Ahrens, W.°, Greiser, H., Linseisen, J., Kluttig, A., Schipf, S., Schmidt, B., Günther, K.: Das Design der
Machbarkeitsstudien für eine bundesweite Kohortenstudie in Deutschland : Die Pretests der Nationalen
Kohorten (NAKO). Bundesgesundheitsbl.-Gesund. 57, 1246-1254 (2014)
Al-Khadra, S., Meisinger, C., Amann, U., Holle, R., Kuch, B., Seidl, H., Kirchberger, I.°: Secondary
prevention medication after myocardial infarction: Persistence in elderly people over the course of 1 year.
Drugs Aging 31, 513-525 (2014)
Albus, C., Ladwig, K.-H., Herrmann-Lingen, C.°: Psychokardiologie: Praxisrelevante Erkenntnisse und
Handlungsempfehlungen. Dtsch. Med. Wochenschr. 139, 596-601 (2014)
Allebrandt, K.V.°, Teder-Laving, M., Kantermann, T., Peters, A., Campbell, H., Rudan, I., Wilson, J.F.,
Metspalu, A., Roenneberg, T.: Chronotype and sleep duration: The influence of season of assessment.
Chronobiol. Int. 31, 731-740 (2014)
page 87 of 247
2015-11-23
#
joint first authors
Almontashiri, N., Chen, H.-H., Mailloux, R., Tatsuta, T, Teng, A., Mahmoud, A, Ho, T., Stewart, N.A.,
Rippstein, P., Harper, M.E., Roberts, R., Willenborg, C., Erdmann, J., CARDIoGRAM Consortium (Döring,
A., Illig, T., Klopp, N., Meisinger, C., Meitinger, T., Peters, A., Wichmann, H.-E.), Pastore, A., McBride,
H., Langer, T., Stewart, A.F.R.°: SPG7 variant escapes phosphorylation-regulated processing by AFG3L2,
elevates mitochondrial ROS, and is associated with multiple clinical phenotypes. Cell Rep. 7, 834-847 (2014)
Altmaier, E.M.°, Emeny, R.T.: Use of metabolomics and proteomics to reveal pathophysiological pathways
in anxiety disorders. Adv. Biol. Psychiatry 29, 128-138 (2014)
Amann, U.°, Kirchberger, I., Heier, M., Zirngibl, A., von Scheidt, W., Kuch, B., Peters, A., Meisinger, C.:
Effect of renin-angiotensin system inhibitors on long-term survival in patients treated with beta blockers and
antiplatelet agents after acute mocardial infarction (from the MONICA/KORA Myocardial Infarction Registry).
Am. J. Cardiol. 114, 329-335 (2014)
Amann, U.°, Kirchberger, I., Heier, M., Golueke, H., von Scheidt, W., Kuch, B., Peters, A., Meisinger, C.:
Long-term survival in patients with different combinations of evidence-based medications after incident acute
myocardial infarction: Results from the MONICA/KORA Myocardial Infarction Registry. Clin. Res. Cardiol.
103, 655-664 (2014)
Analitis, A.°, Michelozzi, P., D'Ippoliti, D., de'Donato, F., Menne, B., Matthies, F., Atkinson, R.W., Iñiguez, C.,
Basagana, X., Schneider, A.E., Lefranc, A., Paldy, A., Bisanti, L., Katsouyanni, K.: Effects of heat waves on
mortality: Effect modification and confounding by air pollutants. Epidemiology 25, 15-22 (2014)
André, R., Bongard, V., Elosua, R., Kirchberger, I., Farmakis, D., Häkkinen, U., Fusco, D., Torre, M., Garel,
P., Araujo, C., Meisinger, C., Lekakis, J., Malmivaara, A., Dovali, M., Pereira, M., Marrugat, J., Ferrieres, J.°:
International differences in acute coronary syndrome patients’ baseline characteristics, clinical management
and outcomes in Western Europe: The EURHOBOP study. Heart 100, 1201-1207 (2014)
page 88 of 247
2015-11-23
#
joint first authors
#
#
Babisch, W.°, Wolf, K., Petz, M., Heinrich, J., Cyrys, J., Peters, A.°: Associations between traffic noise,
particulate air pollution, hypertension, and isolated systolic hypertension in adults: The KORA study. Environ.
Health Perspect. 122, 492-498 (2014)
#
#
Backes, C. , Rühle, F. , Stoll, M., Haas, J., Frese, K., Franke, A., Lieb, W., Wichmann, H.-E., Weis, T.,
Kloos, W., Lenhof, H.P., Meese, E., Katus, H.A., Meder, B., Keller, A.°: Systematic permutation testing in
GWAS pathway analyses: Identification of genetic networks in dilated cardiomyopathy and ulcerative colitis.
BMC Genomics 15:622 (2014)
page 89 of 247
2015-11-23
#
joint first authors
Baumert, J.J., Meisinger, C., Lukaschek, K., Emeny, R.T., Rückert, I.-M., Kruse, J., Ladwig, K.-H.°: A
pattern of unspecific somatic symptoms as long-term premonitory signs of type 2 diabetes: Findings from the
population-based MONICA/KORA cohort study, 1984-2009. BMC Endocr. Disord. 14:87 (2014)
Baumert, J.J., Schneider, B., Lukaschek, K., Emeny, R.T., Meisinger, C., Erazo, N., Dragano, N., Ladwig,
K.-H.°: Adverse conditions at the workplace are associated with increased suicide risk. J. Psychiatr. Res. 57,
90-95 (2014)
Beelen, R.°, Stafoggia, M., Raaschou-Nielsen, O., Andersen, Z.J., Xun, W.W., Katsouyanni, K.,
Dimakopoulou, K., Brunekreef, B., Weinmayr, G., Hoffmann, B., Wolf, K., Samoli, E., Houthuijs, D.,
Nieuwenhuijsen, M., Oudin, A., Forsberg, B., Olsson, D., Salomaa, V., Lanki, T., Yli-Tuomi, T., Oftedal, B.,
Aamodt, G., Nafstad, P., de Faire, U., Pedersen, N.L., Ostenson, C.G., Fratiglioni, L., Penell, J., Korek, M.,
Pyko, A., Eriksen, K.T., Tjønneland, A., Becker, T., Eeftens, M., Bots, M.L., Meliefste, K., Wang, M.,
Bueno-de-Mesquita, B., Sugiri, D., Krämer, U., Heinrich, J., de Hoogh, K., Key, T., Peters, A., Cyrys, J.,
Concin, H., Nagel, G., Ineichen, A., Schaffner, E., Probst-Hensch, N., Dratva, J., Ducret-Stich, R., Vilier, A.,
Clavel-Chapelon, F., Stempfelet, M., Grioni, S., Krogh, V., Tsai, M.Y., Marcon, A., Ricceri, F., Sacerdote, C.,
Galassi, C., Migliore, E., Ranzi, A., Cesaroni, G., Badaloni, C., Forastiere, F., Tamayo, I., Amiano, P.,
Dorronsoro, M., Katsoulis, M., Trichopoulou, A., Vineis, P., Hoek, G.: Long-term exposure to air pollution and
cardiovascular mortality : An analysis of 22 European cohorts. Epidemiology 25, 368-378 (2014)
Beilina, A., Rudenko, I.N., Kaganovich, A., Civiero, L., Chau, H., Kalia, S.K., Kalia, L.V., Lobbestael, E., Chia,
R., Ndukwe, K., Ding, J., Nalls, M.A., EUMODIC Consortium (Illig, T., Lichtner, P.), Olszewski, M., Hauser,
D.N., Kumaran, R., Lozano, A.M., Baekelandt, V., Greene, L.E., Taymans, J.-M., Greggio, E., Cookson,
M.R.°: Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for
sporadic and familial Parkinson disease. Proc. Natl. Acad. Sci. U.S.A. 111, 2626-2631 (2014)
Benyamin, B., Esko, T., Ried, J.S., Radhakrishnan, A., Vermeulen, S.H., Traglia, M., Gögele, M., Anderson,
D., Broer, L., Podmore, C., Luan, J., Kutalik, Z., Sanna, S., van der Meer, P., Tanaka, T., Wang, F., Westra,
H.J., Franke, L., Mihailov, E., Milani, L., Hälldin, J., Winkelmann, J., Meitinger, T., Thiery, J., Peters, A.,
Waldenberger, M., Rendon, A., Jolley, J., Sambrook, J., Kiemeney, L.A., Sweep, F.C., Sala, C.F.,
Schwienbacher, C., Pichler, I., Hui, J., Demirkan, A., Isaacs, A., Amin, N., Steri, M., Waeber, G., Verweij, N.,
Powell, J.E., Nyholt, D.R., Heath, A.C., Madden, P.A., Visscher, P.M., Wright, M.J., Montgomery, G.W.,
Martin, N.G., Hernandez, D., Bandinelli, S., van der Harst, P., Uda, M., Vollenweider, P., Scott, R.A.,
Langenberg, C., Wareham, N.J., van Duijn, C., Beilby, J., Pramstaller, P.P., Hicks, A.A., Ouwehand, W.H.,
Oexle, K., Gieger, C., Metspalu, A., Camaschella, C., Toniolo, D., Swinkels, D.W., Whitfield, J.B.°: Novel loci
affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nat. Commun. 5:4926
(2014)
page 90 of 247
2015-11-23
#
joint first authors
Bidlingmaier, M.°, Friedrich, N., Emeny, R.T., Spranger, J., Wolthers, O.D., Roswall, J., Koerner, A.,
Obermayer-Pietsch, B., Hübener, C., Dahlgren, J., Frystyk, J., Pfeiffer, A.F., Döring, A., Bielohuby, M.,
Wallaschofski, H., Arafat, A.M.: Reference intervals for Insulin-like Growth Factor-1 (IGF-1) from birth to
senescence: Results from a multicenter study using a new automated chemiluminescence IGF-1
immunoassay conforming to recent international recommendations. J. Clin. Endocrinol. Metab. 9, 1712-1721
(2014)
Bind, M.A., Zanobetti, A., Gasparrini, A., Peters, A., Coull, B., Baccarelli, A., Tarantini, L., Koutrakis, P.,
Vokonas, P., Schwartz, J.°: Effects of temperature and relative humidity on DNA methylation. Epidemiology
25, 561-569 (2014)
Birmili, W.°, Rückerl, R., Hoffmann, B., Weinmayr, G., Schins, R., Kuhlbusch, T.A.J., Vogel, A., Weber, K.,
Franck, U., Cyrys, J., Peters, A.: Ultrafeine Aerosolpartikel in der Außenluft: Perspektiven zur Aufklärung
ihrer Gesundheitseffekte. Gefahrstoffe Reinhalt. Luft 74, 492-500 (2014)
Blozik, E.°, Scherer, M., Lacruz, M.E., Ladwig, K.-H.: Diagnostic utility of a one-item question to screen for
depressive disorders: Results from the MONICA/KORA F3 study. BMC Fam. Pract. 14:198 (2013)
Bongaerts, B.W.°, Ziegler, D., Shaw, J.E., Heier, M., Kowall, B., Herder, C., Roden, M., Peters, A.,
Meisinger, C., Rathmann, W.: A clinical screening score for diabetic polyneuropathy: KORA F4 and AusDiab
studies. J. Diab. Complic. 29, 44-49 (2015) [published online 2014]
page 91 of 247
2015-11-23
#
joint first authors
#
#
#
#
Boraska, V. , Franklin, C.S. , Floyd, J.A. , Thornton, L.M. , Huckins, L.M., Southam, L., Rayner, N.W.,
Tachmazidou, I., Klump, K.L., Treasure, J., Lewis, C.M., Schmidt, U., Tozzi, F., Kiezebrink, K., Hebebrand,
J., Gorwood, P., Adan, R.A., Kas, M.J., Favaro, A., Santonastaso, P., Fernández-Aranda, F., Gratacos, M.,
Rybakowski, F., Dmitrzak-Weglarz, M., Kaprio, J., Keski-Rahkonen, A., Raevuori, A., van Furth, E.F.,
Slof-Op 't Landt, M.C., Hudson, J.I., Reichborn-Kjennerud, T., Knudsen, G.P., Monteleone, P., Kaplan, A.S.,
Karwautz, A., Hakonarson, H., Berrettini, W.H., Guo, Y., Li, D., Schork, N.J., Komaki, G., Ando, T., Inoko, H.,
Esko, T., Fischer, K., Männik, K., Metspalu, A., Baker, J.H., Cone, R.D., Dackor, J., DeSocio, J.E., Hilliard,
C.E., O'Toole, J.K., Pantel, J., Szatkiewicz, J.P., Taico, C., Zerwas, S., Trace, S.E., Davis, O.S., Helder, S.,
Bühren, K., Burghardt, R., de Zwaan, M., Egberts, K., Ehrlich, S., Herpertz-Dahlmann, B., Herzog, W.,
Imgart, H., Scherag, A., Scherag, S., Zipfel, S., Boni, C., Ramoz, N., Versini, A., Brandys, M.K., Danner,
U.N., de Kovel, C., Hendriks, J., Koeleman, B.P., Ophoff, R.A., Strengman, E., van Elburg, A.A., Bruson, A.,
Clementi, M., Degortes, D., Forzan, M., Tenconi, E., Docampo, E., Escaramís, G., Jiménez-Murcia, S.,
Lissowska, J., Rajewski, A., Szeszenia-Dabrowska, N., Slopien, A., Hauser, J., Karhunen, L., Meulenbelt, I.,
Slagboom, P.E., Tortorella, A., Maj, M., Dedoussis, G., Dikeos, D., Gonidakis, F., Tziouvas, K., Tsitsika, A.,
Papezova, H., Slachtova, L., Martaskova, D., Kennedy, J.L., Levitan, R.D., Yilmaz, Z., Huemer, J., Koubek,
D., Merl, E., Wagner, G., Lichtenstein, P., Breen, G., Cohen-Woods, S., Farmer, A., McGuffin, P., Cichon, S.,
Giegling, I., Herms, S., Rujescu, D., Schreiber, S., Wichmann, H.-E., Dina, C., Sladek, R., Gambaro, G.,
Soranzo, N., Julià, A., Marsal, S., Rabionet, R., Gaborieau, V., Dick, D.M., Palotie, A., Ripatti, S., Widen, E.,
Andreassen, O.A., Espeseth, T., Lundervold, A., Reinvang, I., Steen, V.M., le Hellard, S., Mattingsdal, M.,
Ntalla, I., Bencko, V., Foretova, L., Janout, V., Navratilova, M., Gallinger, S., Pinto, D., Scherer, S.W.,
Aschauer, H., Carlberg, L., Schosser, A., Alfredsson, L., Ding, B., Klareskog, L., Padyukov, L., Courtet, P.,
Guillaume, S., Jaussent, I., Finan, C., Kalsi, G., Roberts, M., Logan, D.W., Peltonen, L., Ritchie, G.R.,
Barrett, J.C., Estivill, X., Hinney, A., Sullivan, P.F., Collier, D.A., Zeggini, E., Bulik, C.M.°: A genome-wide
association study of anorexia nervosa. Mol. Psychiatry 19, 1085-1094 (2014)
Brandmaier, S., Peijnenburg, W., Durjava, M.K., Kolar, B., Gramatica, P., Papa, E., Bhhatarai, B., Kovarich,
S., Cassani, S., Roy, P.P., Rahmberg, M., Öberg, T., Jeliazkova, N., Golsteijn, L., Comber, M., Charochkina,
L., Novotarskyi, S., Sushko, I., Abdelaziz, A., D'Onofrio, E., Kunwar, P., Ruggiu, F., Tetko, I.V.°: The
QSPR-THESAURUS: The online platform of the CADASTER project. ATLA-Altern. Lab. Anim. 42, 13-24
(2014)
Breitner, S.°, Wolf, K., Peters, A., Schneider, A.E.: Short-term effects of air temperature on cause-specific
cardiovascular mortality in Bavaria, Germany. Heart 100, 1272-1280 (2014)
Breitner, S.°, Wolf, K., Devlin, R.B., Diaz-Sanchez, D., Peters, A., Schneider, A.E.: Short-term effects of
air temperature on mortality and effect modification by air pollution in three cities of Bavaria, Germany: A
time-series analysis. Sci. Total Environ. 485-486, 49-61 (2014)
page 92 of 247
2015-11-23
#
joint first authors
#
#
#
Broer, L. °, Raschenberger, J. , Deelen, J. , Mangino, M., Codd, V., Pietiläinen, K.H., Albrecht, E., Amin, N.,
Budin-Ljosne, I.°, Isaeva, J., Knoppers, B.M., Tassé, A.M., Shen, H.Y., McCarthy, M., ENGAGE Consortium
(Döring, A., Gieger, C., Nitz, B., Rawal, R., Wichmann, H.-E.), Harris, J.M.: Data sharing in large research
consortia: Experiences and recommendations from ENGAGE. Eur. J. Hum. Genet. 22, 317-321 (2014)
Burkart, K.°, Breitner, S., Schneider, A.E., Khan, M.M., Krämer, A., Endlicher, W.: An analysis of heat
effects in different subpopulations of Bangladesh. Int. J. Biometeorol. 58, 227-237 (2014)
Burkart, K.°, Khan, M.M., Schneider, A.E., Breitner, S., Langner, M., Krämer, A., Endlicher, W.: The effects
of season and meteorology on human mortality in tropical climates: A systematic review. Trans. Roy. Soc.
Trop. Med. Hyg. 108, 393-401 (2014)
Burkhardt, K., Kirchberger, I., Heier, M., Zirngibl, A., Kling, E., von Scheidt, W., Kuch, B., Meisinger, C.°:
Hyponatraemia on admission to hospital is associated with increased long-term risk of mortality in survivors
of myocardial infarction. Eur. J. Prev. Cardiol. 22, 1419-1426 (2015) [published online 2014]
Burkhardt, K., Ittermann, T., Heier, M., Kirchberger, I., Völzke, H., Wallaschofski, H., Below, H., Nauck, M.,
Meisinger, C.°: TSH-Referenzbereich bei süddeutschen Erwachsenen: Ergebnisse aus der
bevölkerungsbasierten KORA F4-Studie. Dtsch. Med. Wochenschr. 139, 317-322 (2014)
Byrne, E.M.°, Gehrman, P.R., Medland, S.E., Nyholt, D.R., Heath, A.C., Madden, P.A., Hickie, I.B., van
Duijn, C.M., Henders, A.K., Montgomery, G.W., Martin, N.G., Wray, N.R., Chronogen Consortium
(Meitinger, T., Wichmann, H.-E.): A genome-wide association study of sleep habits and insomnia. Am. J.
Med. Genet. B 162B, 439-451 (2013)
Cesaroni, G.°, Forastiere, F., Stafoggia, M., Andersen, Z.J., Badaloni, C., Beelen, R., Caracciolo, B., de
Faire, U., Erbel, R., Eriksen, K.T., Fratiglioni, L., Galassi, C., Hampel, R., Heier, M., Hennig, F., Hilding, A.,
Hoffmann, B., Houthuijs, D., Jöckel, K.-H., Korek, M., Lanki, T., Leander, K., Magnusson, P.K.E., Migliore,
E., Östenson, C.-G., Overvad, K., Pedersen, N.L., Pekkanen, J.J., Penell, J., Pershagen, G., Pyko, A.,
Raaschou-Nielsen, O., Ranzi, A., Ricceri, F., Sacerdote, C., Salomaa, V., Swart, W., Turunen, A.W., Vineis,
P., Weinmayr, G., Wolf, K., de Hoogh, K., Hoek, G., Brunekreef, B., Peters, A.: Long term exposure to
ambient air pollution and incidence of acute coronary events: Prospective cohort study and meta-analysis in
11 European cohorts from the ESCAPE project. Br. Med. J. 348:f7412 (2014)
page 93 of 247
2015-11-23
#
joint first authors
Chan, Y., Lim, E.T., Sandholm, N., Wang, S.R., McKnight, A.J., Ripke, S., DIAGRAM Consortium (Gieger,
C., Grallert, H., Illig, T., Klopp, N., Müller-Nurasyid, M., Peters, A.), GENIE Consortium, IIBDGC
Consortium, GIANT Consortium (Albrecht, E., Heid, I.M., Thorand, B., Wichmann, H.-E.), Daly, M.J.,
Neale, B.M., Salem, R.M., Hirschhorn, J.N.°: An excess of risk-increasing low-frequency variants can be a
signal of polygenic inheritance in complex diseases. Am. J. Hum. Genet. 94, 437-452 (2014)
Cheng, T.H., Gorman, M., Martin, L., Barclay, E., Casey, G., Colon Cancer Family Registry, CGEMS
(Linseisen, J.), Saunders, B., Thomas, H., Clark, S., Tomlinson, I.°: Common colorectal cancer risk alleles
contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP. Eur.
J. Hum. Genet. 23, 260-263 (2015) [published online 2014]
(2014)
Clement, B.°, Yuille, M., Zaltoukal, K., Wichmann, H.-E., Anton, G., Parodi, B., Kozera, L., Bréchot, C.,
Hofman, P., Dagher, G.: Public biobanks: Calculation and recovery of costs. Sci. Transl. Med. 6:261fs45
(2014)
page 94 of 247
2015-11-23
#
joint first authors
Coffee and Caffeine Genetics Consortium, Cornelis, M.C., Byrne, E.M., Esko, T., Nalls, M.A., Ganna, A.,
Paynter, N., Monda, K.L., Amin, N., Fischer, K., Renström, F., Ngwa, J.S., Huikari, V., Cavadino, A., Nolte,
I.M., Teumer, A., Yu, K., Marques-Vidal, P., Rawal, R., Manichaikul, A., Wojczynski, M.K., Vink, J.M., Zhao,
J.H., Burlutsky, G., Lahti, J., Mikkilä, V., Lemaitre, R.N., Eriksson, J., Musani, S.K., Tanaka, T., Geller, F.,
Luan, J., Hui, J., Mägi, R., Dimitriou, M., Garcia, M.E., Ho, W.K., Wright, M.J., Rose, L.M., Magnusson, P.K.,
Pedersen, N.L., Couper, D., Oostra, B.A., Hofman, A., Ikram, M.A., Tiemeier, H.W., Uitterlinden, A.G., van
Rooij, F.J., Barroso, I., Johansson, I., Xue, L., Kaakinen, M., Milani, L., Power, C., Snieder, H., Stolk, R.P.,
Baumeister, S.E., Biffar, R., Gu, F., Bastardot, F., Kutalik, Z., Jacobs, D.R., Forouhi, N.G., Mihailov, E., Lind,
L., Lindgren, C., Michaelsson, K., Morris, A., Jensen, M., Khaw, K.T., Luben, R.N., Wang, J.J., Männisto, S.,
Perälä, M.M., Kähönen, M., Lehtimäki, T., Viikari, J., Mozaffarian, D., Mukamal, K.J., Psaty, B.M., Döring,
A., Heath, A.C., Montgomery, G.W., Dahmen, N., Carithers, T., Tucker, K.L., Ferrucci, L., Boyd, H.A.,
Melbye, M., Treur, J.L., Mellström, D., Hottenga, J.J., Prokopenko, I., Tönjes, A., Deloukas, P., Kanoni, S.,
Lorentzon, M., Houston, D.K., Liu, Y., Danesh, J., Rasheed, A., Mason, M.A., Zonderman, A.B., Franke, L.,
Kristal, B.S., International Parkinson's Disease Genomics Consortium (IPDGC) (Illig, T., Lichtner, P.), North
American Brain Expression Consortium, UK Brain Expression Consortium, Karjalainen, J., Reed, D.R.,
Westra, H.J., Evans, M.K., Saleheen, D., Harris, T.B., Dedoussis, G., Curhan, G., Stumvoll, M., Beilby, J.,
Pasquale, L.R., Feenstra, B., Bandinelli, S., Ordovas, J.M., Chan, A.T., Peters, U., Ohlsson, C., Gieger, C.,
Martin, N.G., Waldenberger, M., Siscovick, D.S., Raitakari, O., Eriksson, J.G., Mitchell, P., Hunter, D.J.,
Kraft, P., Rimm, E.B., Boomsma, D.I., Borecki, I.B., Loos, R.J., Wareham, N.J., Vollenweider, P., Caporaso,
N., Grabe, H.J., Neuhouser, M.L., Wolffenbuttel, B.H., Hu, F.B., Hyppönen, E., Jarvelin, M.R., Cupples, L.A.,
Franks, P.W., Ridker, P.M., van Duijn, C.M., Heiss, G., Metspalu, A., North, K.E., Ingelsson, E., Nettleton,
J.A., van Dam, R.M., Chasman, D.I.°: Genome-wide meta-analysis identifies six novel loci associated with
habitual coffee consumption. Mol. Psychiatry 20, 647-656 (2015) [published online 2014]
Consonni, D.°, De Matteis, S., Pesatori, A.C., Bertazzi, P.A., Olsson, A.C., Kromhout, H., Peters, S.,
Vermeulen, R.C., Pesch, B., Brüning, T., Kendzia, B., Behrens, T., Stücker, I., Guida, F., Wichmann, H.-E.,
Brüske, I., Landi, M.T., Caporaso, N.E., Gustavsson, P., Plato, N., Tse, L.A., Yu, I.T., Jockel, K.H., Ahrens,
W., Pohlabeln, H., Merletti, F., Richiardi, L., Simonato, L., Forastiere, F., Siemiatycki, J., Parent, M., Tardón,
A., Boffetta, P., Zaridze, D., Chen, Y., Field, J.K., 't Mannetje, A., Pearce, N., McLaughlin, J., Demers, P.,
Lissowska, J., Szeszenia-Dabrowska, N., Bencko, V., Foretova, L., Janout, V., Rudnai, P., Fabianova, E.,
Stanescu Dumitru, R., Bueno-de-Mesquita, H.B., Schüz, J., Straif, K.: Lung cancer risk among bricklayers in
a pooled analysis of case-control studies. Int. J. Cancer 136, 360-371 (2015) [published online 2014]
Cyrys, J.°, Peters, A., Soentgen, J., Wichmann, H.-E.: Low emission zones reduce PM10 mass
concentrations and diesel soot in German cities. J. Air Waste Manag. Assoc. 64, 481-487 (2014)
page 95 of 247
2015-11-23
#
joint first authors
de Hoogh, K.°, Korek, M., Vienneau, D., Keuken, M., Kukkonen, J.V.K., Nieuwenhuijsen, M.J., Badaloni, C.,
Beelen, R., Bolignano, A., Cesaroni, G., Pradas, M.C., Cyrys, J., Douros, J., Eeftens, M., Forastiere, F.,
Forsberg, B., Fuks, K., Gehring, U., Gryparis, A., Gulliver, J., Hansell, A.L., Hoffmann, B., Johansson, C.,
Jonkers, S., Kangas, L., Katsouyanni, K., Künzli, N., Lanki, T., Memmesheimer, M., Moussiopoulos, N.,
Modig, L., Pershagen, G., Probst-Hensch, N., Schindler, C., Schikowski, T., Sugiri, D., Teixidó, O., Tsai,
M.Y., Yli-Tuomi, T., Brunekreef, B., Hoek, G., Bellander, T.: Comparing land use regression and dispersion
modelling to assess residential exposure to ambient air pollution for epidemiological studies. Environ. Int. 73,
382-392 (2014)
Debette, S.°, Kamatani, Y., Metso, T.M., Kloss, M., Chauhan, G., Engelter, S.T., Pezzini, A., Thijs, V.,
Markus, H.S., Dichgans, M., Wolf, C., Dittrich, R., Touzé, E., Southerland, A.M., Samson, Y., Abboud, S.,
Béjot, Y., Caso, V., Bersano, A., Gschwendtner, A., Sessa, M., Cole, J., Lamy, C., Medeiros, E., Beretta, S.,
Bonati, L.H., Grau, A.J., Michel, P., Majersik, J.J., Sharma, P., Kalashnikova, L., Nazarova, M., Dobrynina,
L., Bartels, E., Guillon, B., van den Herik, E.G., Fernandez-Cadenas, I., Jood, K., Nalls, M.A., de Leeuw,
F.E., Jern, C., Cheng, Y.C., Werner, I., Metso, A.J., Lichy, C., Lyrer, P.A., Brandt, T., Boncoraglio, G.B.,
Wichmann, H.-E., Gieger, C., Johnson, A.D., Böttcher, T., Castellano, M., Arveiler, D., Ikram, M.A., Breteler,
M.M., Padovani, A., Meschia, J.F., Kuhlenbäumer, G., Rolfs, A., Worrall, B.B., Ringelstein, E.B., Zelenika,
D., Tatlisumak, T., Lathrop, M., Leys, D.: Common variation in PHACTR1 is associated with susceptibility to
cervical artery dissection. Nat. Genet. 47, 78-83 (2015) [published online 2014]
Deckert, A.°, Winkler, V., Meisinger, C., Heier, M., Becher, H.: Myocardial infarction incidence and ischemic
heart disease mortality: Overall and trend results in repatriates, Germany. Eur. J. Public Health 24, 127-133
(2014)
Deffner, V.°, Küchenhoff, H., Maier, V., Pitz, M., Cyrys, J., Breitner, S., Schneider, A.E., Gu, J.,
Geruschkat, U., Peters, A.: Personal exposure to ultrafine particles: Two-level statistical modeling of
background exposure and time-activity patterns during three seasons. J. Expo. Sci. Environ. Epidemiol.,
DOI: 10.1038/jes.2014.73 (2014)
Denholm, R., Schüz, J., Straif, K., Stücker, I., Jockel, K.H., Brenner, D.R., De Matteis, S., Boffetta, P., Guida,
F., Brüske, I., Wichmann, H.-E., Landi, M.T., Caporaso, N., Siemiatycki, J., Ahrens, W., Pohlabeln, H.,
Zaridze, D., Field, J.K., McLaughlin, J., Demers, P., Szeszenia-Dabrowska, N., Lissowska, J., Rudnai, P.,
Fabianova, E., Dumitru, R.S., Bencko, V., Foretova, L., Janout, V., Kendzia, B., Peters, S., Behrens, T.,
Vermeulen, R., Brüning, T., Kromhout, H., Olsson, A.C.°: Is previous respiratory disease a risk factor for lung
cancer? Am. J. Respir. Crit. Care Med. 190, 549-559 (2014)
page 96 of 247
2015-11-23
#
joint first authors
234-244 (2014)
Dias, A.°, Gorzelniak, L., Rudnik, J., Stojanovic, D., Horsch, A.: Detecting periodic limb movements with
off-the-shelf accelerometers: A feasibility study. Stud. Health Technol. Inform. 192, 152-156 (2013)
1990-1998 (2014)
Dimakopoulou, K., Samoli, E., Beelen, R., Stafoggia, M., Andersen, Z.J., Hoffmann, B., Fischer, P.,
Nieuwenhuijsen, M., Vineis, P., Xun, W., Hoek, G., Raaschou-Nielsen, O., Oudin, A., Forsberg, B., Modig, L.,
Jousilahti, P., Lanki, T., Turunen, A., Oftedal, B., Nafstad, P., Schwarze, P.E., Penell, J., Fratiglioni, L.,
Andersson, N., Pedersen, N., Korek, M., de Faire, U., Eriksen, K.T., Tjonneland, A., Becker, T., Wang, M.,
Bueno-de-Mesquita, B., Tsai, M., Eeftens, M., Peeters, P.H., Meliefste, K., Marcon, A., Krämer, U.,
Kuhlbusch, T.A.J., Vossoughi, M., Key, T., de Hoogh, K., Hampel, R., Peters, A., Heinrich, J., Weinmayr,
G., Concin, H., Nagel, G., Ineichen, A., Jacquemin, B., Stempfelet, M., Vilier, A., Ricceri, F., Sacerdote, C.,
Pedeli, X., Katsoulis, M., Trichopoulou, A., Brunekreef, B., Katsouyanni, K.°: Air pollution and nonmalignant
respiratory mortality in 16 cohorts within the ESCAPE project. Am. J. Respir. Crit. Care Med. 189, 684-696
(2014)
#
#
Dong, J. , Gao, J. , Nalls, M., Gao, X., Huang, X., Han, J., Singleton, A.B., Chen, H.°, International
Parkinson's Disease Genomics Consortium (IPDGC) (Illig, T., Lichtner, P.): Susceptibility loci for
pigmentation and melanoma in relation to Parkinson's disease. Neurobiol. Aging 35, 1512.e5-1512.e10
(2014)
Dullaart, R.P., Al-Daghri, N.M., Ashina, M., Bouzas-Mosquera, A., Brunetti, N.D., Buechler, C., Chen, H.S.,
Corrales, J.J., D'Archivio, M., Cas, A.D., Pino, G.G., Gómez-Abril, S.A., Győri, D., Haslacher, H., Herder, C.,
Kerstens, M.N., Koutsilieris, M., Lombardi, C., Lupattelli, G., Mócsai, A., Msaouel, P., Orfao, A., Ormazabal,
P., Pacher, R., Perkmann, T., Peteiro, J., Plischke, M., Reynaert, N.L., Ricci, M.A., Robles, N.R., Rocha, M.,
Rutten, E.P., Sabico, S., Santamaria, F., Santoro, F., Schmid, A., Schmidt, M., Schytz, H.W., Shyu, K.G.,
Tada, H., Thorand, B., Valerio, G., Vesely, D.L., Wu, T.E., Yamagishi, M., Yeh, Y.T.: Research update for
articles published in EJCI in 2012. Eur. J. Clin. Invest. 44, 1010-1023 (2014)
Durant, J.L.°, Beelen, R., Eeftens, M., Meliefste, K., Cyrys, J., Heinrich, J., Bellander, T., Lewne, M.,
Brunekreef, B., Hoek, G.: Comparison of ambient airborne PM2.5, PM2.5 absorbance and nitrogen dioxide
ratios measured in 1999 and 2009 in three areas in Europe. Sci. Total Environ. 487, 290-298 (2014)
page 97 of 247
2015-11-23
#
joint first authors
Eeftens, M.°, Hoek, G., Gruzieva, O., Mölter, A., Agius, R.M., Beelen, R., Brunekreef, B., Custovic, A.,
Cyrys, J., Fuertes, E., Heinrich, J., Hoffmann, B., de Hoogh, K., Jedynska, A., Keuken, M., Klümper, C.,
Kooter, I.M., Krämer, U., Korek, M., Koppelman, G.H., Kuhlbusch, T.A.J., Simpson, A., Smit, H.A., Tsai,
M.Y., Wang, M., Wolf, K., Pershagen, G., Gehring, U.: Elemental composition of particulate matter and the
association with lung function. Epidemiology 25, 648-657 (2014)
Eichholzer, M.°, Richard, A., Nicastro, H.L., Platz, E.A., Linseisen, J., Rohrmann, S.: Urinary lignans and
inflammatory markers in the US National Health and Nutrition Examination Survey (NHANES) 1999-2004
and 2005-2008. Cancer Causes Control 25, 395-403 (2014)
Eichholzer, M.°, Richard, A., Walser-Domjan, E., Linseisen, J., Rohrmann, S.: Urinary phytoestrogen levels
and frailty in older American women of the National Health and Nutrition Examination Survey (NHANES)
1999-2002: A cross-sectional study. Ann. Nutr. Metab. 63, 269-276 (2013)
Ellis, J., Lange, E.M., Li, J., Dupuis, J., Baumert, J.J., Walston, J.D., Keating, B.J., Durda, P., Fox, E.R.,
Palmer, C.D., Meng, Y.A., Young, T., Farlow, D.N., Schnabel, R.B., Marzi, C., Larkin, E., Martin, L.W., Bis,
J.C., Auer, P., Ramachandran, V.S., Gabriel, S.B., Willis, M.S., Pankow, J.S., Papanicolaou, G.J., Rotter,
J.I., Ballantyne, C.M., Gross, M.D., Lettre, G., Wilson, J.G., Peters, U., Koenig, W., Tracy, R.P., Redline, S.,
Reiner, A.P., Benjamin, E.J., Lange, L.A.°: Large multiethnic candidate gene study for C-reactive protein
levels: Identification of a novel association at CD36 in African Americans. Hum. Genet. 133, 985-995 (2014)
Emeny, R.T., Bidlingmaier, M., Lacruz, M.E., Linkohr, B., Peters, A., Reincke, M., Ladwig, K.-H.°: Mind
over hormones: Sex differences in associations of well-being with IGF-I, IGFBP-3 and physical activity in the
KORA-Age study. Exp. Gerontol. 59, 58-64 (2014)
Emerging Risk Factors Collaboration (Meisinger, C.), di Angelantonio, E., Gao, P., Khan, H., Butterworth,
A.S., Wormser, D., Kaptoge, S., Kondapally Seshasai, S.R., Thompson, A., Sarwar, N., Willeit, P., Ridker,
P.M., Barr, E.L., Khaw, K.T., Psaty, B.M., Brenner, H., Balkau, B., Dekker, J.M., Lawlor, D.A., Daimon, M.,
Willeit, J., Njølstad, I., Nissinen, A., Brunner, E.J., Kuller, L.H., Price, J.F., Sundström, J., Knuiman, M.W.,
Feskens, E.J., Verschuren, W.M., Wald, N., Bakker, S.J., Whincup, P.H., Ford, I., Goldbourt, U., Gómez de
la Cámara, A., Gallacher, J., Simons, L.A., Rosengren, A., Sutherland, S.E., Björkelund, C., Blazer, D.G.,
Wassertheil-Smoller, S., Onat, A., Marin Ibañez, A., Casiglia, E., Jukema, J.W., Simpson, L.M., Giampaoli,
S., Nordestgaard, B.G., Selmer, R., Wennberg, P., Kauhanen, J., Salonen, J.T., Dankner, R.,
Barrett-Connor, E., Kavousi, M., Gudnason, V., Evans, D., Wallace, R.B., Cushman, M., D'Agostino, R.B.,
Umans, J.G., Kiyohara, Y., Nakagawa, H., Sato, S., Gillum, R.F., Folsom, A.R., van der Schouw, Y.T.,
Moons, K.G., Griffin, S.J., Sattar, N., Wareham, N.J., Selvin, E., Thompson, S.G., Danesh, J.°: Glycated
hemoglobin measurement and prediction of cardiovascular disease. JAMA 311, 1225-1233 (2014)
Fan, Y.M.°, Hernesniemi, J., Oksala, N., Levula, M., Raitoharju, E., Collings, A., Hutri-Kähönen, N., Juonala,
M., Marniemi, J., Lyytikäinen, L.P., Seppälä, I., Mennander, A., Tarkka, M., Kangas, A.J., Soininen, P.,
Salenius, J.P., Klopp, N., Illig, T., Laitinen, T., Ala-Korpela, M., Laaksonen, R., Viikari, J., Kähönen, M.,
Raitakari, O.T., Lehtimäki, T.: Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein
metabolism in women and USF1 expression in atherosclerotic plaque. Sci. Rep. 4:4650 (2014)
page 98 of 247
2015-11-23
#
joint first authors
Fensterer, V.°, Küchenhoff, H., Maier, V., Wichmann, H.-E., Breitner, S., Peters, A., Gu, J., Cyrys, J.:
Evaluation of the impact of low emission zone and heavy traffic ban in Munich (Germany) on the reduction of
PM10 in ambient air. Int. J. Environ. Res. Public Health 11, 5094-5112 (2014)
Ferrario, M.M.°, Veronesi, G., Chambless, L.E., Tunstall-Pedoe, H.D., Kuulasmaa, K.A., Salomaa, V.V.,
Borglykke, A., Hart, N., Söderberg, S., Cesana, G.C., MORGAM Project (Döring, A., Wichmann, H.-E.):
The contribution of educational class in improving accuracy of cardiovascular risk prediction across
European regions: The MORGAM Project Cohort Component. Heart 100, 1179-1187 (2014)
Flannick, J., Thorleifsson, G., Beer, N.L., Jacobs, S.B., Grarup, N., Burtt, N.P., Mahajan, A., Fuchsberger, C.,
Atzmon, G., Benediktsson, R., Blangero, J., Bowden, D.W., Brandslund, I., Brosnan, J., Burslem, F.,
Chambers, J., Cho, Y.S., Christensen, C., Douglas, D.A., Duggirala, R., Dymek, Z., Farjoun, Y., Fennell, T.,
Fontanillas, P., Forsen, T., Gabriel, S., Glaser, B., Gudbjartsson, D.F., Hanis, C., Hansen, T., Hreidarsson,
A.B., Hveem, K., Ingelsson, E., Isomaa, B., Johansson, S., Jørgensen, T., Jørgensen, M.E., Kathiresan, S.,
Kong, A., Kooner, J., Kravic, J., Laakso, M., Lee, J.Y., Lind, L., Lindgren, C.M., Linneberg, A., Masson, G.,
Meitinger, T., Mohlke, K.L., Molven, A., Morris, A.P., Potluri, S., Rauramaa, R., Ribel-Madsen, R., Richard,
A.M., Rolph, T., Salomaa, V., Segrè, A.V., Skärstrand, H., Steinthorsdottir, V., Stringham, H.M., Sulem, P.,
Tai, E.S., Teo, Y.Y., Teslovich, T.M., Thorsteinsdottir, U., Trimmer, J.K., Tuomi, T., Tuomilehto, J.,
Vaziri-Sani, F., Voight, B.F., Wilson, J.G., Boehnke, M., McCarthy, M.I., Njølstad, P.R., Pedersen, O., GoT2D
Consortium (Stefansson, K.°, Altshuler, D.°, Grallert, H., Huth, C., Kriebel, J., Meisinger, C.,
Müller-Nurasyid, M., Peters, A., Ried, J.S., Strauch, K., Strom, T.M.), T2D-GENES Consortium, Groop,
L., Cox, D.R.: Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nat. Genet. 46,
357-363 (2014)
9:e105116 (2014)
Fowkes, F.G.R.°, Murray, G.D., Butcher, I., Folsom, A.R., Hirsch, A.T., Couper, D.J., Debacker, G.,
Kornitzer, M., Newman, A.B., Sutton-Tyrrell, K.C., Cushman, M., Lee, A.J., Price, J.F., D'Agostino, R.B.,
Murabito, J.M., Norman, P.E., Masaki, K.H., Bouter, L.M., Heine, R.J., Stehouwer, C.D.A., McDermott, M.M.,
Stoffers, H.E.J.H., Knottnerus, J.A., Ogren, M., Hedblad, B., Koenig, W., Meisinger, C., Cauley, J.A.,
Franco, O.H., Hunink, M.G.M., Hofman, A., Witteman, J.C., Criqui, M.H., Langer, R.D., Hiatt, W.R.,
Hamman, R.F.: Development and validation of an ankle brachial index risk model for the prediction of
cardiovascular events. Eur. J. Prev. Cardiol. 21, 310-320 (2014)
Freese, J.°, Feller, S., Harttig, U., Kleiser, C., Linseisen, J., Fischer, B., Leitzmann, M.F., Six-Merker, J.,
Michels, K.B., Nimptsch, K., Steinbrecher, A., Pischon, T., Heuer, T., Hoffmann, I., Jacobs, G., Boeing, H.,
Nöthlings, U.: Development and evaluation of a short 24-h food list as part of a blended dietary assessment
strategy in large-scale cohort studies. Eur. J. Clin. Nutr. 68, 324-329 (2014)
page 99 of 247
2015-11-23
#
joint first authors
Freitag-Wolf, S., Dommisch, H., Graetz, C., Jockel-Schneider, Y., Harks, I., Staufenbiel, I., Meyle, J.,
Eickholz, P., Noack, B., Bruckmann, C., Gieger, C., Jepsen, S., Lieb, W., Schreiber, S., König, I.R., Schäfer,
A.S.°: Genome-wide exploration identifies sex-specific genetic effects of alleles upstream NPY to increase
the risk of severe periodontitis in men. J. Clin. Periodontol. 41, 1115-1121 (2014)
Friedrich, N.#, Wolthers, O.D.#, Arafat, A.M.#, Emeny, R.T., Spranger, J., Roswall, J., Kratzsch, J., Grabe,
H.J., Hübener, C., Pfeiffer, A.F.H., Döring, A., Bielohuby, M., Dahlgren, J., Frystyk, J.J., Wallaschofski, H.,
Bidlingmaier, M.°: Age- and sex-specific reference intervals across life span for Insulin-like Growth Factor
Binding Protein 3 (IGFBP-3) and the IGF-i to IGFBP-3 ratio measured by new automated
chemiluminescence assays. J. Clin. Endocrinol. Metab. 99, 1675-1686 (2014)
Fuertes, E., Macintyre, E., Agius, R.M., Beelen, R., Brunekreef, B., Bucci, S., Cesaroni, G., Cirach, M.,
Cyrys, J., Forastiere, F., Gehring, U., Gruzieva, O., Hoffmann, B., Jedynska, A., Keuken, M., Klümper, C.,
Kooter, I.M., Korek, M., Krämer, U., Mölter, A., Nieuwenhuijsen, M., Pershagen, G., Porta, D., Postma, D.S.,
Simpson, A., Smit, H.A., Sugiri, D., Sunyer, J., Wang, M., Heinrich, J.°: Associations between particulate
matter elements and early-life pneumonia in seven birth cohorts: Results from the ESCAPE and
TRANSPHORM projects. Int. J. Hyg. Environ. Health 217, 819-829 (2014)
Fuertes, E., Söderhäll, C., Acevedo, N., Becker, A., Brauer, M., Chan-Yeung, M., Dijk, N.F., Heinrich, J., de
Jongste, J., Koppelman, G.H., Postma, D.S., Kere, J., Kozyrskyj, A.L., Pershagen, G., Sandford, A.J.,
Standl, M., Tiesler, C.M., Waldenberger, M., Westman, M., Carlsten, C., Melén, E.°: Associations between
the 17q21 region and allergic rhinitis in 5 birth cohorts. J. Allergy Clin. Immunol. 135, 573-576 (2015)
Fuks, K., Weinmayr, G., Foraster, M., Dratva, J., Hampel, R., Houthuijs, D., Oftedal, B., Oudin, A.,
Panasevich, S., Penell, J., Sommar, J.N., Sørensen, M., Tiittanen, P., Wolf, K., Xun, W.W., Aguilera, I.,
Basagana, X., Beelen, R., Bots, M.L., Brunekreef, B., Bueno-de-Mesquita, H.B., Caracciolo, B., Cirach, M.,
de Faire, U., de Nazelle, A., Eeftens, M., Elosua, R., Erbel, R., Forsberg, B., Fratiglioni, L., Gaspoz, J.M.,
Hilding, A., Jula, A., Korek, M., Krämer, U., Künzli, N., Lanki, T., Leander, K., Magnusson, P.K., Marrugat, J.,
Nieuwenhuijsen, M.J., Ostenson, C.G., Pedersen, N.L., Pershagen, G., Phuleria, H.C., Probst-Hensch, N.M.,
Raaschou-Nielsen, O., Schaffner, E., Schikowski, T., Schindler, C., Schwarze, P.E., Søgaard, A.J., Sugiri,
D., Swart, W.J., Tsai, M.Y., Turunen, A.W., Vineis, P., Peters, A., Hoffmann, B.°: Arterial blood pressure and
long-term exposure to traffic-related air pollution: An analysis in the European Study of Cohorts for Air
Pollution Effects (ESCAPE). Environ. Health Perspect. 122, 896-905 (2014)
page 100 of 247
2015-11-23
#
joint first authors
#
#
#
#
#
#
#
#
95, 49-65 (2014)
German National Cohort (GNC) Consortium (Linseisen, J., Peters, A.): The German National Cohort: Aims,
study design and organization. Eur. J. Epidemiol. 29, 371-382 (2014)
Gorski, M., Tin, A., Garnaas, M., McMahon, G.M., Chu, A.Y., Tayo, B.O., Pattaro, C., Teumer, A., Chasman,
D.I., Chalmers, J., Hamet, P., Tremblay, J., Woodward, M., Aspelund, T., Eiriksdottir, G., Gudnason, V.,
Harris, T.B., Launer, L.J., Smith, A.V., Mitchell, B.D., O'Connell, J.R., Shuldiner, A.R., Coresh, J., Li, M.,
Freudenberger, P., Hofer, E., Schmidt, H., Schmidt, R., Holliday, E.G., Mitchell, P., Wang, J.J., de Boer, I.H.,
Li, G., Siscovick, D.S., Kutalik, Z., Corre, T., Vollenweider, P., Waeber, G., Gupta, J., Kanetsky, P.A.,
Hwang, S.J., Olden, M., Yang, Q., de Andrade, M., Atkinson, E.J., Kardia, S.L., Turner, S.T., Stafford, J.M.,
Ding, J., Liu, Y., Barlassina, C., Cusi, D., Salvi, E., Staessen, J.A., Ridker, P.M., Grallert, H., Meisinger, C.,
Müller-Nurasyid, M., Krämer, B.K., Kramer, H., Rosas, S.E., Nolte, I.M., Penninx, B.W., Snieder, H., Fabiola
Del Greco, M., Franke, A., Nöthlings, U., Lieb, W., Bakker, S.J., Gansevoort, R.T., van der Harst, P.,
Dehghan, A., Franco, O.H., Hofman, A., Rivadeneira, F., Sedaghat, S., Uitterlinden, A.G., Coassin, S., Haun,
M., Kollerits, B., Kronenberg, F., Paulweber, B., Aumann, N., Endlich, K., Pietzner, M., Völker, U., Rettig, R.,
Chouraki, V., Helmer, C., Lambert, J.C., Metzger, M., Stengel, B., Lehtimäki, T., Lyytikäinen, L.P., Raitakari,
O., Johnson, A., Parsa, A., Bochud, M., Heid, I.M., Goessling, W., Köttgen, A., Kao, W.H., Fox, C.S., Böger,
C.A.°: Genome-wide association study of kidney function decline in individuals of European descent. Kidney
Int. 87, 1017–1029 (2015) [published online 2014]
Gorski, M., Winkler, T.W., Stark, K., Müller-Nurasyid, M., Ried, J.S., Grallert, H., Weber, B.H.F., Heid,
I.M.°: Harmonization of study and reference data by PhaseLift: Saving time when imputing study data.
Genet. Epidemiol. 38, 381-388 (2014)
Gorzelniak, L., Dias, A., Bakhirev, A., Knoll, A., Horsch, A.°: Does the low power mode of the actigraph
GT3X+ accelerometer influence the device output in sleep research in healthy subjects? Stud. Health
Technol. Inform. 192, 1172 (2013)
page 101 of 247
2015-11-23
#
joint first authors
Gu, J.°, Kraus, U., Schneider, A.E., Hampel, R., Pitz, M., Breitner, S., Wolf, K., Hänninen, O., Peters, A.,
Cyrys, J.: Personal day-time exposure to ultrafine particles in different microenvironments. Int. J. Hyg.
Environ. Health 218, 188-195 (2015) [published online 2014]
Haberl, N.°, Hirn, S., Wenk, A., Diendorf, J., Epple, M., Johnston, B.D., Krombach, F., Kreyling, W.G.,
Schleh, C.: Cytotoxic and proinflammatory effects of PVP-coated silver nanoparticles after intratracheal
instillation in rats. Beilstein J. Nanotechnol. 4, 933-940 (2013)
Hartiala, J., Bennett, B.J., Tang, W.H.W., Wang, Z., Stewart, A.F.R., Roberts, R., McPherson, R.,
CARDIoGRAM Consortium (Döring, A., Illig, T., Klopp, N., Meisinger, C., Meitinger, T., Peters, A.,
Wichmann, H.-E.), Lusis, A., Hazen, S.L., Allayee, H.°: Comparative genome-wide association studies in
mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and l-carnitine.
Arterioscler. Thromb. Vasc. Biol. 34, 1307-1313 (2014)
Herder, C.°, Bongaerts, B.W., Rathmann, W., Heier, M., Kowall, B., Koenig, W., Thorand, B., Roden, M.,
Meisinger, C.°, Ziegler, D.°: Differential association between biomarkers of subclinical inflammation and
painful polyneuropathy: Results from the KORA F4 study. Diabetes Care 38, 91-96 (2015) [published online
2014]
#
#
#
Herder, C. °, Nuotio, M.L. , Shah, S. , Blankenberg, S., Brunner, E.J., Carstensen, M., Gieger, C., Grallert,
4343-4359 (2014)
J. Med. Genet. B 165, 283-293 (2014)
page 102 of 247
2015-11-23
#
joint first authors
Hoggart, C.J., Venturini, G., Mangino, M., Gomez, F., Ascari, G., Zhao, J.H., Teumer, A., Winkler, T.W.,
Tsernikova, N., Luan, J., Mihailov, E., Ehret, G.B., Zhang, W., Lamparter, D., Esko, T., Mace, A., Rüeger, S.,
Bochud, P.Y., Barcella, M., Dauvilliers, Y., Benyamin, B., Evans, D.M., Hayward, C., Lopez, M.F., Franke, L.,
Russo, A., Heid, I.M., Salvi, E., Vendantam, S., Arking, D.E., Boerwinkle, E., Chambers, J.C., Fiorito, G.,
Grallert, H., Guarrera, S., Homuth, G., Huffman, J.E., Porteous, D.J., Generation Scotland Consortium
(Loos, R.J.), LifeLines Cohort Study (Rivolta, C.), GIANT Consortium (Albrecht, E., Gieger, C., Heid, I.M.,
Illig, T., Kutalik, Z.°, Müller-Nurasyid, M., Thorand, B., Wichmann, H.-E.), Moradpour, D., Iranzo, A.,
Hebebrand, J., Kemp, J.P., Lammers, G.J., Aubert, V., Heim, M.H., Martin, N.G., Montgomery, G.W.,
Peraita-Adrados, R., Santamaría, J., Negro, F., Schmidt, C.O., Scott, R.A., Spector, T.D., Strauch, K.,
Völzke, H., Wareham, N.J., Yuan, W., Bell, J.T., Chakravarti, A., Kooner, J.S., Peters, A., Matullo, G.,
Wallaschofski, H., Whitfield, J.B., Paccaud, F., Vollenweider, P., Bergmann, S., Beckmann, J.S., Tafti, M.,
Hastie, N.D., Cusi, D., Bochud, M., Frayling, T.M., Metspalu, A., Jarvelin, M.R., Scherag, A., Smith, G.D.,
Borecki, I.B., Rousson, V., Hirschhorn, J.N.: Novel approach identifies SNPs in SLC2A10 and KCNK9 with
evidence for parent-of-origin effect on Body Mass Index. PLoS Genet. 10:e1004508 (2014)
Holmes, M.V.#°, Asselbergs, F.W.#, Palmer, T.M.#, Drenos, F., Lanktree, M.B., Nelson, C.P., Dale, C.E.,
Padmanabhan, S., Finan, C., Swerdlow, D.I., Tragante, V., van Iperen, E.P., Sivapalaratnam, S., Shah, S.,
Elbers, C.C., Shah, T., Engmann, J., Giambartolomei, C., White, J., Zabaneh, D., Sofat, R., McLachlan, S.,
Doevendans, P.A., Balmforth, A.J., Hall, A.S., North, K.E., Almoguera, B., Hoogeveen, R.C., Cushman, M.,
Fornage, M., Patel, S.R., Redline, S., Siscovick, D.S., Tsai, M.Y., Karczewski, K.J., Hofker, M.H.,
Verschuren, W.M., Bots, M.L., van der Schouw, Y.T., Melander, O., Dominiczak, A.F., Morris, R.W.,
Ben-Shlomo, Y., Price, J.F., Kumari, M., Baumert, J.J., Peters, A., Thorand, B., Koenig, W., Gaunt, T.R.,
Humphries, S.E., Clarke, R., Watkins, H., Farrall, M., Wilson, J.G., Rich, S.S., de Bakker, P.I., Lange, L.A.,
Davey Smith, G., Reiner, A.P., Talmud, P.J., Kivimaki, M., Lawlor, D.A., Dudbridge, F., Samani, N.J.,
Keating, B.J., Hingorani, A.D., Casas, J.P.: Mendelian randomization of blood lipids for coronary heart
disease. Eur. Heart J. 36, 539-550 (2015) [published online 2014]
Holmes, M.V., Exeter, H.J., Folkersen, L., Nelson, C.P., Guardiola, M., Cooper, J.A., Sofat, R., Boekholdt,
S.M., Khaw, K.T., Li, K.W., Smith, A.J., van't Hooft, F.M., Eriksson, P., Franco-Cereceda, A., Asselbergs,
F.W., Boer, J.M., Onland-Moret, N.C., Hofker, M.H., Erdmann, J., Kivimaki, M., Kumari, M., Reiner, A.P.,
Keating, B.J., Humphries, S.E., Hingorani, A.D., Mallat, Z., Samani, N.J., Talmud, P.J.°, CARDIoGRAM
Consortium (Döring, A., Illig, T., Klopp, N., Meisinger, C., Meitinger, T., Peters, A., Wichmann, H.-E.):
Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA(2))-V isoenzyme
in coronary heart disease modified mendelian randomization analysis using PLA2G5 expression levels. Circ.
Cardiovasc. Genet. 7, 144-150 (2014)
Hornhardt, S.°, Rößler, U., Sauter, W., Rosenberger, A., Illig, T., Bickeböller, H., Wichmann, H.-E.,
Gomolka, M.: Genetic factors in individual radiation sensitivity. DNA Repair 16, 54-65 (2014)
Huckins, L.M.°, Boraska, V., Franklin, C.S., Floyd, J.A.B., Southam, L., EUMODIC Consortium (Wichmann,
H.-E.), Sullivan, P.F., Bulik, C.M., Collier, D.A., Tyler-Smith, C., Zeggini, E., Tachmazidou, I.: Using
ancestry-informative markers to identify fine structure across 15 populations of European origin. Eur. J. Hum.
Genet. 22, 1190-1200 (2014)
page 103 of 247
2015-11-23
#
joint first authors
Hunger, M.°, Kirchberger, I., Holle, R., Seidl, H., Kuch, B., Wende, R., Meisinger, C.: Does nurse-based
case management for aged myocardial infarction patients improve risk factors, physical functioning and
mental health? The KORINNA trial. Eur. J. Prev. Cardiol. 22, 442-450 (2015) [published online 2014]
Huth, C., Thorand, B., Baumert, J.J., Kruse, J., Emeny, R.T., Schneider, A.E., Meisinger, C., Ladwig,
K.-H.°: Job strain as a risk factor for the onset of type 2 diabetes mellitus: Findings from the MONICA/KORA
Augsburg cohort study. Psychosom. Med. 76, 562-568 (2014)
Icks, A.°, Claessen, H.°, Kirchberger, I., Heier, M., Peters, A., Trentinaglia, I., Giani, G., von Scheidt, W.,
Meisinger, C.: Mortality after first myocardial infarction in diabetic and non-diabetic people between 1985
and 2009. The MONICA/KORA registry. Eur. J. Epidemiol. 29, 899-909 (2014)
Jedynska, A.°, Hoek, G., Wang, M., Eeftens, M., Cyrys, J., Keuken, M., Ampe, C., Beelen, R., Cesaroni, G.,
Forastiere, F., Cirach, M., de Hoogh, K., de Nazelle, A., Nystad, W., Declercq, C., Eriksen, K.T.,
Dimakopoulou, K., Lanki, T., Meliefste, K., Nieuwenhuijsen, M.J., Yli-Tuomi, T., Raaschou-Nielsen, O.,
Brunekreef, B., Kooter, I.M.: Development of land use regression models for elemental, organic carbon, PAH
and hopanes/steranes in 10 ESCAPE/TRANSPHORM European study areas. Environ. Sci. Technol. 48,
14435-14444 (2014)
Jedynska, A.°, Hoek, G.V.D., Wang, M., Eeftens, M., Cyrys, J., Beelen, R.M.J., Cirach, M., de Nazelle, A.,
Keuken, M.P., Visschedijk, A.J.H., Nystad, W., Akhlaghi, H.M., Meliefste, K., Nieuwenhuijsen, M.J., de
Hoogh, K., Brunekreef, B., Kooter, I.M.: Spatial variations of levoglucosan in four European study areas. Sci.
Total Environ. 505, 1072-1081 (2015) [published online 2014]
Jedynska, A.°, Hoek, G., Eeftens, M., Cyrys, J., Keuken, M., Ampe, C., Beelen, R., Cesaroni, G., Forastiere,
F., Cirach, M., de Hoogh, K., de Nazelle, A., Madsen, C., Declercq, C., Eriksen, K.T., Katsouyanni, K.,
Akhlaghi, H.M., Lanki, T., Meliefste, K., Nieuwenhuijsen, M., Oldenwening, M., Pennanen, A.,
Raaschou-Nielsen, O., Brunekreef, B., Kooter, I.M.: Spatial variations of PAH, hopanes/steranes and EC/OC
concentrations within and between European study areas. Atmos. Environ. 87, 239-248 (2014)
Jobski, K., Amann, U., Suzart, K., Wallander, M.A., Schink, T., Garbe, E.°: Use of rivaroxaban in Germany:
A database drug utilization study of a drug started in hospital. Eur. J. Clin. Pharmacol. 70, 975-981 (2014)
Johar, H., Emeny, R.T., Bidlingmaier, M., Reincke, M., Thorand, B., Peters, A., Heier, M., Ladwig, K.-H.°:
Blunted diurnal cortisol pattern is associated with frailty: A cross-sectional study of 745 participants aged 65
to 90 years. J. Clin. Endocrinol. Metab. 99, E464-E468 (2014)
page 104 of 247
2015-11-23
#
joint first authors
Johar, H., Emeny, R.T., Bidlingmaier, M., Lacruz, M.E., Reincke, M., Peters, A., Heier, M., Ladwig, K.-H.°:
Lower morning to evening cortisol ratio is associated with cognitive impairment in men but not women: An
analysis of 733 older subjects of the cross-sectional KORA-Age study. Psychoneuroendocrinol. 51, 296-306
Kälsch, H., Hennig, F., Moebus, S., Möhlenkamp, S., Dragano, N., Jakobs, H., Memmesheimer, M.°, Erbel,
R., Jockel, K.H., Hoffmann, B.°, Heinz Nixdorf Recall Study Investigative Group (Löwel, H.): Are air pollution
and traffic noise independently associated with atherosclerosis: The Heinz Nixdorf Recall Study. Eur. Heart
J. 35, 853-860 (2014)
Kirchberger, I.°, Braitmayer, K., Coenen, M., Oberhauser, C., Meisinger, C.: Feasibility and psychometric
properties of the German 12-item WHO Disability Assessment Schedule (WHODAS 2.0) in a
population-based sample of patients with myocardial infarction from the MONICA/KORA myocardial
infarction registry. Popul. Health Metr. 12:27 (2014)
Kirchberger, I.°, Meisinger, C., Golüke, H., Heier, M., Kuch, B., Peters, A., Quinones, P.A., von Scheidt,
W., Mielck, A.: Long-term survival among older patients with myocardial infarction differs by educational
level: Results from the MONICA/KORA myocardial infarction registry. Int. J. Equity Health 13:19 (2014)
Klug, G., Lacruz, M.E., Emeny, R.T., Häfner, S., Ladwig, K.-H., Huber, D.°: Aging without depression: A
cross-sectional study. Psychodyn. Psychiatry 42, 5-22 (2014)
Koivula, R.W., Heggie, A., Barnett, A., Cederberg, H., Hansen, T.H., Koopman, A.D., Ridderstråle, M.,
Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M.W., Perry, M.H., Rauh, S., Siloaho, M.,
Teare, H.J., Thorand, B., Bell, J., Brunak, S., Frost, G., Jablonka, B., Mari, A., McDonald, T.J., Dekker, J.M.,
Hansen, T., Hattersley, A., Laakso, M., Pedersen, O., Koivisto, V., Ruetten, H., Walker, M., Pearson, E.,
Franks, P.W.°, DIRECT Consortium: Discovery of biomarkers for glycaemic deterioration before and after the
onset of type 2 diabetes: Rationale and design of the epidemiological studies within the IMI DIRECT
Consortium. Diabetologia 57, 1132-1142 (2014)
page 105 of 247
2015-11-23
#
joint first authors
Kreyling, W.G.°, Fertsch-Gapp, S., Schäffler, M., Johnston, B.D., Haberl, N., Pfeiffer, C., Diendorf, J.,
Schleh, C., Hirn, S., Semmler-Behnke, M., Epple, M., Parak, W.J.: In vitro and in vivo interactions of
selected nanoparticles with rodent serum proteins and their consequences in biokinetics. Beilstein J.
Nanotechnol. 5, 1699-1711 (2014)
Kreyling, W.G.°, Hirn, S., Möller, W., Schleh, C., Wenk, A., Celik, G., Lipka, J., Schäffler, M., Haberl, N.,
Johnston, B.D., Sperling, R.A., Schmid, G., Simon, U., Parak, W.J., Semmler-Behnke, M.: Air-blood barrier
translocation of tracheally instilled gold nanoparticles inversely depends on particle size. ACS Nano 8,
222-233 (2014)
Kronenberg, F., Kollerits, B., Kiechl, S., Lamina, C., Kedenko, L., Meisinger, C., Willeit, J., Huth, C.,
Wietzorrek, G., Altmann, M.E., Thorand, B., Melmer, A., Dähnhardt, D., Santer, P., Rathmann, W.,
Paulweber, B., Koenig, W., Peters, A., Adham, I.M., Dieplinger, H.°: Plasma concentrations of afamin are
associated with the prevalence and development of metabolic syndrome. Circ. Cardiovasc. Genet. 7,
822-829 (2014)
Kühn, A., Nieters, A., Köttgen, A., Goek, O.N., Michels, K., Nöthlings, U., Jacobs, G., Meisinger, C.,
Pessler, F., Akmatov, M.F., Kühnisch, J., Moebus, S., Glocker, E., Naus, S., Keimling, M., Leitzmann, M.,
Linseisen, J., Sarioglu, H., von Toerne, C., Hauck, S.M., Wallaschofski, H., Wichmann, H.-E., Illig, T.°:
Feasibility and quality development of biomaterials in the pretest studies of the German National Cohort.
Bundesgesundheitsbl.-Gesund. 57, 1255-1263 (2014)
page 106 of 247
2015-11-23
#
joint first authors
Ladwig, K.-H.°, Waller, C.: Geschlechtsspezifische
Aspekte
bei
der
koronaren
Herzkrankheit.
Ladwig, K.-H.°: Kritische Lebensereignisse. Public Health Forum 22, 10-12 (2014)
Ladwig, K.-H.°, Lederbogen, F., Albus, C., Angermann, C., Borggrefe, M., Fischer, D., Fritzsche, K., Haass,
M., Jordan, J., Jünger, J., Kindermann, I., Köllner, V., Kuhn, B., Scherer, M., Seyfarth, M., Völler, H., Waller,
C., Herrmann-Lingen, C.: Position paper on the importance of psychosocial factors in cardiology: Update
2013. GMS Psycho-Social-Medicine 12:Doc09 (2014)
Lamina, C., Haun, M., Coassin, S., Kloss-Brandstätter, A., Gieger, C., Peters, A., Grallert, H., Strauch, K.,
Meitinger, T., Kedenko, L., Paulweber, B., Kronenberg, F.°: A systematic evaluation of short tandem repeats
in lipid candidate genes: Riding on the SNP-wave. PLoS ONE 9:e102113 (2014)
Lamina, C., Linsenmeyer, J., Weissensteiner, H., Kollerits, B., Meisinger, C., Rantner, B., Stöckl, D.,
Stadler, M., Klein-Weigel, P., Peters, A., Fraedrich, G., Kronenberg, F.°: Correlation between a positive
family risk score and peripheral artery disease in one case-control and two population-based studies.
Atherosclerosis 237, 243-250 (2014)
Lanzinger, S.°, Hampel, R., Breitner, S., Rückerl, R., Kraus, U., Cyrys, J., Geruschkat, U., Peters, A.,
Schneider, A.E.: Short-term effects of air temperature on blood pressure and pulse pressure in potentially
susceptible individuals. Int. J. Hyg. Environ. Health 217, 775-784 (2014)
Lanzinger, S.°, Breitner, S., Neas, L., Cascio, W., Diaz-Sanchez, D., Hinderliter, A., Peters, A., Devlin,
R.B., Schneider, A.E.: The impact of decreases in air temperature and increases in ozone on markers of
endothelial function in individuals having type-2 diabetes. Environ. Res. 134, 331-338 (2014)
Laschkolnig, A., Kollerits, B., Lamina, C., Meisinger, C., Rantner, B., Stadler, M., Peters, A., Koenig, W.,
Stöckl, A., Dähnhardt, D., Böger, C.A., Krämer, B.K., Fraedrich, G., Strauch, K., Kronenberg, F.°:
Lipoprotein (a) concentrations, apolipoprotein (a) phenotypes, and peripheral arterial disease in three
independent cohorts. Cardiovasc. Res. 103, 28-36 (2014)
(2014)
Lee, K.W., Abrahamowicz, M., Leonard, G.T., Richer, L., Perron, M., Veillette, S., Reischl, E., Bouchard, L.,
Gaudet, D., Paus, T., Pausova, Z.°: Prenatal exposure to cigarette smoke interacts with OPRM1 to modulate
dietary preference for fat. J. Psychiatry Neurosci. 39:130263 (2015) [published online 2014]
page 107 of 247
2015-11-23
#
joint first authors
Lee, K.W., Richmond, R., Hu, P., French, L., Shin, J.T., Bourdon, C., Reischl, E., Waldenberger, M.,
Zeilinger, S., Gaunt, T.R., McArdle, W., Ring, S., Woodward, G., Bouchard, L., Gaudet, D., Davey-Smith,
G., Relton, C., Paus, T., Pausova, Z.°: Prenatal exposure to maternal cigarette smoking and DNA
methylation: Epigenome-wide association in a discovery sample of adolescents and replication in an
independent cohort at birth through 17 years of age. Environ. Health Perspect. 123, 193-199 (2015)
Li, Q., Wojciechowski, R., Simpson, C.L., Hysi, P.G., Verhoeven, V.J., Ikram, M.K., Höhn, R., Vitart, V.,
Hewitt, A.W., Oexle, K., Mäkelä, K.M., MacGregor, S., Pirastu, M., Fan, Q., Cheng, C.Y., St. Pourcain, B.,
McMahon, G., Kemp, J.P., Northstone, K., Rahi, J.S., Cumberland, P.M., Martin, N.G., Sanfilippo, P.G., Lu,
Y., Wang, Y.X., Hayward, C., Polasek, O., Campbell, H., Bencic, G., Wright, A.F., Wedenoja, J., Zeller, T.,
Schillert, A., Mirshahi, A., Lackner, K.J., Yip, S.P., Yap, M.K.H., Ried, J.S., Gieger, C., Murgia, F., Wilson,
J.F., Fleck, B., Yazar, S., Vingerling, J.R., Hofman, A., Uitterlinden, A., Rivadeneira, F., Amin, N., Karssen,
L.C., Oostra, B.A., Zhou, X., Teo, Y.Y., Tai, E.S., Vithana, E., Barathi, V.A., Zheng, Y., Siantar, R.G.,
Neelam, K., Shin, Y.K., Lam, J.S.Y., Yonova-Doing, E., Venturini, C., Hosseini, S.M., Wong, H.S., Lehtimäki,
T., Kähönen, M., Raitakari, O., Timpson, N.J., Evans, D.M., Khor, C.C., Aung, T., Young, T.L., Mitchell, P.,
Klein, B., van Duijn, C.M., Meitinger, T., Jonas, J.B., Baird, P.N., Mackey, D.A., Wong, T.Y., Saw, S.M.,
Pärssinen, O., Stambolian, D., Hammond, C.J., Klaver, C.C., Williams, C., Paterson, A.D., Bailey-Wilson,
J.E., Guggenheim, J.A.°: Genome-wide association study for refractive astigmatism reveals genetic
co-determination with spherical equivalent refractive error: The CREAM consortium. Hum. Genet. 134,
Lieb, W., Chen, M.H., Teumer, A., de Boer, R.A., Lin, H., Fox, E.R., Musani, S.K., Wilson, J.G., Wang, T.J.,
Völzke, H., Petersen, A.K., Meisinger, C., Nauck, M., Schlesinger, S., Li, Y., Ménard, J., Hercberg, S.,
Wichmann, H.-E., Völker, U., Rawal, R., Bidlingmaier, M., Hannemann, A., Dörr, M., Rettig, R., van Gilst,
W.H., van Veldhuisen, D.J., Bakker, S.J., Navis, G., Wallaschofski, H., Meneton, P., van der Harst, P.,
Reincke, M., Vasan, R.S.°, CKDGen Consortium, ICBP Consortium, EchoGen Consortium: Genome-wide
meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and
prekallikrein genes. Circ. Cardiovasc. Genet. 8, 131-140 (2015) [published online 2014]
Little, M.H.R.°, Reitmeir, P., Peters, A., Leidl, R.: The impact of differences between patient and general
population EQ-5D-3L values on the mean tariff scores of different patient groups. Value Health 17, 364-371
(2014)
Lluis, A., Ballenberger, N., Illi, S., Schieck, M., Kabesch, M., Illig, T., Schleich, I., von Mutius, E., Schaub,
B.°: Regulation of TH17 markers early in life through maternal farm exposure. J. Allergy Clin. Immunol. 133,
864-871 (2014)
page 108 of 247
2015-11-23
#
joint first authors
#
#
#
#
#
#
#
#
#
Genet. 46, 669-677 (2014)
Lubitz, S.A.°, Lunetta, K.L., Lin, H., Arking, D.E., Trompet, S., Li, G., Krijthe, B.P., Chasman, D.I., Barnard,
J., Kleber, M.E., Dörr, M., Ozaki, K., Smith, A.V., Müller-Nurasyid, M., Walter, S., Agarwal, S.K., Bis, J.C.,
Brody, J.A., Chen, L.Y., Everett, B.M., Ford, I., Franco, O.H., Harris, T.B., Hofman, A., Kääb, S., Mahida, S.,
Kathiresan, S., Kubo, M., Launer, L.J., Macfarlane, P.W., Magnani, J.W., McKnight, B., McManus, D.D.,
Peters, A., Psaty, B.M., Rose, L.M., Rotter, J.I., Silbernagel, G., Smith, J.D., Sotoodehnia, N., Stott, D.J.,
Taylor, K.D., Tomaschitz, A., Tsunoda, T., Uitterlinden, A.G., van Wagoner, D.R., Völker, U., Völzke, H.,
Murabito, J.M., Sinner, M.F., Gudnason, V., Felix, S.B., Marz, W., Chung, M., Albert, C.M., Stricker, B.H.,
Tanaka, T., Heckbert, S.R., Jukema, J.W., Alonso, A., Benjamin, E.J., Ellinor, P.T.: Novel genetic markers
associate with atrial fibrillation risk in Europeans and Japanese. J. Am. Coll. Cardiol. 63, 1200-1210 (2014)
Lukaschek, K., Baumert, J.J., Krawitz, M., Erazo, N., Förstl, H., Ladwig, K.-H.°: Determinants of
completed railway suicides by psychiatric in-patients: Case-control study. Br. J. Psychiatry 205, 398-406
(2014)
Lukaschek, K., Baumert, J.J., Erazo, N., Ladwig, K.-H.°: Stable time patterns of railway suicides in
Germany: Comparative analysis of 7,187 cases across two observation periods (1995-1998; 2005-2008).
BMC Public Health 14:124 (2014)
Lukaschek, K.: Suizidprävention. Public Health Forum 22, 46-48 (2014)
page 109 of 247
2015-11-23
#
joint first authors
Lüneburg, N.°, Lieb, W., Zeller, T., Chen, M.H., Maas, R., Carter, A.M., Xanthakis, V., Glazer, N.L.,
Schwedhelm, E., Seshadri, S., Ikram, M.A., Longstreth, W.T. J.r., Fornage, M., König, I.R., Loley, C., Ojeda,
F.M., Schillert, A., Wang, T.J., Sticht, H., Kittel, A., König, J., Benjamin, E.J., Sullivan, L.M., Bernges, I.,
Anderssohn, M., Ziegler, A., Gieger, C., Illig, T., Meisinger, C., Wichmann, H.-E., Wild, P.S., Schunkert, H.,
Psaty, B.M., Wiggins, K.L., Heckbert, S.R., Smith, N., Lackner, K.J., Lunetta, K.L., Blankenberg, S.,
Erdmann, J., Münzel, T., Grant, P.J., Vasan, R.S., Böger, R.H.: Genome-wide association study of L-arginine
and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine. Circ. Cardiovasc.
Genet. 7, 864-872 (2014)
Ma, C., Blackwell, T., Boehnke, M., Scott, L.J.°, GoT2D Consortium (Gieger, C., Grallert, H., Hrabě de
Angelis, M., Huth, C., Kriebel, J., Meisinger, C., Meitinger, T., Müller-Nurasyid, M., Peters, A.,
Rathmann, W., Ried, J.S., Strauch, K., Strom, T.M.): Recommended joint and meta-analysis strategies for
case-control association testing of single low-count variants. Genet. Epidemiol. 37, 539-550 (2013)
MacIntyre, E.A., Gehring, U., Mölter, A., Fuertes, E., Klümper, C., Krämer, U., Quass, U., Hoffmann, B.,
Gascon, M., Brunekreef, B., Koppelman, G.H., Beelen, R., Hoek, G., Birk, M., de Jongste, J.C., Smit, H.A.,
Cyrys, J., Gruzieva, O., Korek, M., Bergström, A., Agius, R.M., de Vocht, F., Simpson, A., Porta, D.,
Forastiere, F., Badaloni, C., Cesaroni, G., Esplugues, A., Fernández-Somoano, A., Lerxundi, A., Sunyer, J.,
Cirach, M., Nieuwenhuijsen, M.J., Pershagen, G., Heinrich, J.°: Air pollution and respiratory infections
during early childhood: An analysis of 10 European birth cohorts within the ESCAPE project. Environ. Health
Perspect. 122, 107-113 (2014)
Natl. Acad. Sci. U.S.A. 111, 13127-13132 (2014)
Maron, J.°, Hunger, M., Kirchberger, I., Peters, A., Mielck, A., KORA Study Group (Heinrich, J., Holle,
R., Leidl, R., Meisinger, C., Strauch, K.): Nimmt die gesundheitliche Ungleichheit zu?
page 110 of 247
2015-11-23
#
joint first authors
#
#
#
Medici, M. °, Porcu, E. , Pistis, G. , Teumer, A., Brown, S.J., Jensen, R.A., Rawal, R., Roef, G.L., Plantinga,
Meisinger, C.°, Ittermann, T., Tiller, D., Agger, C., Nauck, M., Schipf, S., Wallaschofski, H., Jørgensen, T.,
Linneberg, A., Thiery, J., Kluttig, A., Greiser, K.H., Werdan, K., Burkhardt, K., Völzke, H.: Sex-specific
associations between thyrotropin and serum lipid profiles. Thyroid 24, 424-432 (2014)
Missios, P., Zhou, Y., Guachalla, L.M., von Figura, G., Wegner, A., Chakkarappan, S.R., Binz, T., Gompf, A.,
Hartleben, G., Burkhalter, M.D., Wulff, V., Günes, C., Wang-Sattler, R., Song, Z., Illig, T., Klaus, S., Böhm,
B.O., Wenz, T., Hiller, K., Rudolph, K.L.°: Glucose substitution prolongs maintenance of energy homeostasis
and lifespan of telomere dysfunctional mice. Nat. Commun. 5:4924 (2014)
Mölter, A.°, Simpson, A., Berdel, D., Brunekreef, B., Custovic, A., Cyrys, J., de Jongste, J., de Vocht, F.,
Fuertes, E., Gehring, U., Gruzieva, O., Heinrich, J., Hoek, G., Hoffmann, B., Klümper, C., Korek, M.,
Kuhlbusch, T.A.J., Lindley, S., Postma, D., Tischer, C.G., Wijga, A., Pershagen, G., Agius, R.M.: A
multicentre study of air pollution exposure and childhood asthma prevalence: The ESCAPE project. Eur.
Respir. J. 45, 610-624 (2015) [published online 2014]
Mueller, M.°, Strobl, R., Jahn, K., Linkohr, B., Ladwig, K.-H., Mielck, A., Grill, E.: Impact of vertigo and
dizziness on self-perceived participation and autonomy in older adults: Results from the KORA-Age study.
Qual. Life Res. 23, 2301-2308 (2014)
page 111 of 247
2015-11-23
#
joint first authors
#
#
Muendlein, A. °, Kinz, E. , Gasser, K., Leiherer, A., Rein, P., Saely, C.H., Grallert, H., Peters, A.,
Fraunberger, P., Drexel, H., Lang, A.H.: Occurrence of the JAK2 V617F mutation in patients with peripheral
arterial disease. Am. J. Hematol. 90, E17-E21 (2015) [published online 2014]
Mühlenbruch, K., Ludwig, T., Jeppesen, C., Joost, H.G., Rathmann, W., Meisinger, C., Peters, A., Boeing,
H., Thorand, B., Schulze, M.B.°: Update of the German Diabetes Risk Score and external validation in the
German MONICA/KORA study. Diabetes Res. Clin. Pract. 104, 459-466 (2014)
Nassab, M.H., Rhein, M., Heese, P., Glahn, A., Frieling, H., Linnebank, M., Bleich, S., Kornhuber, J.,
Heberlein, A., Grallert, H., Peters, A., Rawal, R., Strauch, K., Hillemacher, T.: No association between the
ALDH2 promoter polymorphism rs886205, alcohol dependence, and risky alcohol consumption in a German
population. Psychiatr. Genet. 25, 41-42 (2015) [published online 2014]
Newby, D.E., Mannucci, P.M., Tell, G.S., Baccarelli, A.A., Brook, R.D., Donaldson, K., Forastiere, F.,
Franchini, M., Franco, O.H., Graham, I., Hoek, G., Hoffmann, B., Hoylaerts, M.F., Künzli, N., Mills, N.L.,
Pekkanen, J., Peters, A., Piepoli, M.F., Rajagopalan, S., Storey, R.F.°: Expert position paper on air pollution
and cardiovascular disease. Eur. Heart J. 36, 83-93 (2015) [published online 2014]
#
#
Ng, M.C.Y. , Shriner, D. , Chen, B.H., Li, J., Chen, W., Guo, X., Liu, J., Bielinski, S.J., Yanek, L.R., Nalls,
M.A., Comeau, M.E., Rasmussen-Torvik, L.J., Jensen, R.A., Evans, D.S., Sun, Y.V., An, P., Patel, S.R., Lu,
Y., Long, J., Armstrong, L.L., Wagenknecht, L., Yang, L., Snively, B.M., Palmer, N.D., Mudgal, P., Langefeld,
C.D., Keene, K.L., Freedman, B.I., Mychaleckyj, J.C., Nayak, U., Raffel, L.J., Goodarzi, M.O., Chen, Y.I.,
Taylor, H.A., Correa, A., Sims, M., Couper, D., Pankow, J.S., Boerwinkle, E., Adeyemo, A., Doumatey, A.,
Chen, G., Mathias, R.A., Vaidya, D., Singleton, A.B., Zonderman, A.B., Igo, R.P., Sedor, J.R., FIND
Consortium, Kabagambe, E.K., Siscovick, D.S., McKnight, B., Rice, K., Liu, Y., Hsueh, W.C., Zhao, W.,
Bielak, L.F., Kraja, A., Province, M.A., Bottinger, E.P., Gottesman, O., Cai, Q., Zheng, W., Blot, W.J., Lowe,
W.L., Pacheco, J.A., Crawford, D.C., eMERGE Consortium, DIAGRAM Consortium (Gieger, C., Grallert, H.,
Illig, T., Klopp, N., Müller-Nurasyid, M., Peters, A.), Grundberg, E., MuTHER Consortium, Rich, S.S.,
Hayes, M.G., Shu, X., Loos, R.J.F., Borecki, I.B., Peyser, P.A., Cummings, S.R., Psaty, B.M., Fornage, M.,
Iyengar, S.K., Evans, M.K., Becker, D.M., Kao, W.H.L., Wilson, J.G., Rotter, J.I., Sale, M.M., Liu, S.°, Rotimi,
C.N.°, Bowden, D.W.°, MEDIA Consortium: Meta-analysis of genome-wide association studies in African
Americans provides insights into the genetic architecture of type 2 diabetes. PLoS Genet. 10:e100451
(2014)
Obayashi, M., Stevanin, G., Synofzik, M., Monin, M.L., Duyckaerts, C., Sato, N., Streichenberger, N.,
Vighetto, A., Desestret, V., Tesson, C., Wichmann, H.-E., Illig, T., Huttenlocher, J., Kita, Y., Izumi, Y.,
Mizusawa, H., Schöls, L., Klopstock, T., Brice, A.°, Ishikawa, K., Durr, A.: Spinocerebellar ataxia type 36
exists in diverse populations and can be caused by a short hexanucleotide GGCCTG repeat expansion. J.
Neurol. Neurosurg. Psychiatr. 86, 986-995 (2015) [published online 2014]
Ortlieb, S., Gorzelniak, L., Nowak, D., Strobl, R., Grill, E., Thorand, B., Peters, A., Kuhn, K.A., Karrasch,
S., Horsch, A., Schulz, H.°: Associations between multiple accelerometry-assessed physical activity
parameters and selected health outcomes in elderly people - results from the KORA-Age study. PLoS ONE
9:e111206 (2014)
page 112 of 247
2015-11-23
#
joint first authors
Ortlieb, S., Dias, A., Gorzelniak, L., Nowak, D., Karrasch, S., Peters, A., Kuhn, K.A., Horsch, A., Schulz,
S.°: Exploring patterns of accelerometry-assessed physical activity in elderly people. Int. J. Behav. Nutr.
Phys. Act. 11:28 (2014)
Pabst, G., Zimmermann, A.-K., Huth, C., Koenig, W., Ludwig, T., Zierer, A., Peters, A., Thorand, B.°:
Association of low 25-hydroxyvitamin D levels with the frailty syndrome in an aged population: Results from
the KORA-Age Augsburg study. J. Nutr. Health Aging 19, 258-264 (2015) [published online 2014]
Pechlaner, R., Willeit, P., Summerer, M., Santer, P., Egger, G., Kronenberg, F., Demetz, E., Weiss, G.,
Tsimikas, S., Witztum, J.L., Willeit, K., Iglseder, B., Paulweber, B., Kedenko, L., Haun, M., Meisinger, C.,
Gieger, C., Müller-Nurasyid, M., Peters, A., Willeit, J., Kiechl, S.°: Heme oxygenase-1 gene promoter
microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular
disease. Arterioscler. Thromb. Vasc. Biol. 35, 229-236 (2015) [published online 2014]
Pennells, L., Kaptoge, S., White, I.R., Thompson, S.G., Wood, A.M.°, Emerging Risk Factors Collaboration
(Meisinger, C.): Assessing risk prediction models using individual participant data from multiple studies. Am.
J. Epidemiol. 179, 621-632 (2014)
#
#
Perry, J.R. °, Hsu, Y.H. , Chasman, D.I., Johnson, A.D., Elks, C.E., Albrecht, E., Andrulis, I.L., Beesley, J.,
Berenson, G.S., Bergmann, S., Bojesen, S.E., Bolla, M.K., Brown, J., Buring, J.E., Campbell, H.,
Chang-Claude, J., Chenevix-Trench, G., Corre, T., Couch, F.J., Cox, A., Czene, K., d'Adamo, A.P., Davies,
G., Deary, I.J., Dennis, J., Easton, D.F., Engelhardt, E.G., Eriksson, J.G., Esko, T., Fasching, P.A., Figueroa,
J.D., Flyger, H., Fraser, A., Garcia-Closas, M., Gasparini, P., Gieger, C., Giles, G.G., Guénel, P., Hägg, S.,
Hall, P., Hayward, C., Hopper, J.L., Ingelsson, E., kConFab Investigators, Kardia, S.L., Kasiman, K., Knight,
J.A., Lahti, J., Lawlor, D.A., Magnusson, P.K., Margolin, S., Marsh, J.A., Metspalu, A., Olson, J.E., Pennell,
C.E., Polasek, O., Rahman, I., Ridker, P.M., Robino, A., Rudan, I., Rudolph, A., Salumets, A., Schmidt, M.K.,
Schoemaker, M.J., Smith, E.N., Smith, J.A., Southey, M., Stöckl, D., Swerdlow, A.J., Thompson, D.J.,
Truong, T., Ulivi, S., Waldenberger, M., Wang, Q., Wild, S., Wilson, J.F., Wright, A.F., Zgaga, L., RepoGen
Consortium, Ong, K.K., Murabito, J.M., Karasik, D., Murray, A.°: DNA mismatch repair gene MSH6
implicated in determining age at natural menopause. Hum. Mol. Genet. 23, 2490-2497 (2014)
page 113 of 247
2015-11-23
#
joint first authors
#
#
#
#
Perry, J.R.B. °, Day, F. , Elks, C.E. , Sulem, P. , Thompson, D.J., Ferreira, T., He, C., Chasman, D.I., Esko,
T., Thorleifsson, G., Albrecht, E., Ang, W.Q., Corre, T., Cousminer, D.L., Feenstra, B., Franceschini, N.,
Ganna, A., Johnson, A.D., Kjellqvist, S., Lunetta, K.L., McMahon, G., Nolte, I.M., Paternoster, L., Porcu, E.,
Smith, A.V., Stolk, L., Teumer, A., Tsernikova, N., Tikkanen, E., Ulivi, S., Wagner, E.K., Amin, N., Bierut,
L.J., Byrne, E.M., Hottenga, J.-J., Koller, D.L., Mangino, M., Pers, T.H., Yerges-Armstrong, L.M, Zhao, J.H.,
Andrulis, I.L., Anton-Culver, H., Atsma, F., Bandinelli, S., Beckmann, M.W., Benítez, J., Blomqvist, C.,
Bojesen, S.E., Bolla, M.K., Bonanni, B., Brauch, H., Brenner, H., Buring, J.E., Chang-Claude, J., Chanock,
S., Chen, J., Chenevix-Trench, G., Collee, J.M., Couch, F.J., Couper, D., Coviello, A.D., Cox, A., Czene, K.,
D’adamo, A.P., Smith, G.D., de Vivo, I., Demerath, E.W., Dennis, J., Devilee, P., Dieffenbach, A.K., Dunning,
A.M., Eiriksdottir, G., Eriksson, J.G., Fasching, P.A., Ferrucci, L., Flesch-Janys, D., Flyger, H., Foroud, T.,
Franke, L., Garcia, M.E., Garcia-Closas, M., Geller, F., de Geus, E.J., Giles, G.G., Gudbjartsson, D.F.,
Gudnason, V., Guénel, P., Guo, S., Hall, P., Hamann, U., Haring, R., Hartman, C.A., Heath, A.C., Hofman,
A., Hooning, M.J., Hopper, J.L., Hu, F.B., Hunter, D.J., Karasik, D., Kiel, D.P., Knight, J.A., Kosma, V.M.,
Kutalik, Z., Lai, S., Lambrechts, D., Lindblom, A., Mägi, R., Magnusson, P.K., Mannermaa, A., Martin, N.G.,
Masson, G., McArdle, P.F., McArdle, W.L., Melbye, M., Michailidou, K., Mihailov, E., Milani, L., Milne, R.L.,
Nevanlinna, H., Neven, P., Nohr, E.A., Oldehinkel, A.J., Oostra, B.A., Palotie, A., Peacock, M., Pedersen,
N.L., Peterlongo, P., Peto, J., Pharoah, P.D.P., Postma, D.S., Pouta, A., Pylkäs, K., Radice, P., Ring, S.,
Rivadeneira, F., Robino, A., Rose, L.M., Rudolph, A., Salomaa, V., Sanna, S., Schlessinger, D., Schmidt,
M.K., Southey, M.C., Sovio, U., Stampfer, M., Stöckl, D., Storniolo, A., Timpson, N.J., Tyrer, J., Visser, J.A.,
Vollenweider, P., Völzke, H., Waeber, G., Waldenberger, M., Wallaschofski, H., Wang, Q., Willemsen, G.,
Winqvist, R., Wolffenbuttel, B.H.R., Wright, M.J., Boomsma, D.I., Econs, M.J., Khaw, K.-T., Loos, R.J.F.,
McCarthy, M.I., Montgomery, G.W., Rice, J.P., Streeten, E.A., Thorsteinsdottir, U., van Duijn, C.M., Alizadeh,
B.Z., Bergmann, S., Boerwinkle, E., Boyd, H.A., Crisponi, L., Gasparini, P., Gieger, C., Harris, T.B.,
Ingelsson, E., Järvelin, M.-R., Kraft, P., Lawlor, D., Metspalu, A., Pennell, C.E., Ridker, P.M., Snieder, H.,
Sørensen, T.I., Spector, T.D., Strachan, D.P., Uitterlinden, A.G., Wareham, N.J., Widen, E., Zygmunt, M.,
Murray, A., Easton, D.F., Stefansson, K., Murabito, J.M.°, Ong, K.K.: Parent-of-origin specific allelic
associations among 106 genomic1 loci for age at menarche. Nature 514, 92-97 (2014)
Pichler, I.#, del Greco, M.F.#, Gögele, M., Lill, C.M., Bertram, L., Do, C.B., Eriksson, N., Foroud, T., Myers,
R.H., PD GWAS Consortium, Nalls, M., Keller, M.F., International Parkinson's Disease Genomics
Consortium (IPDGC) (Illig, T., Lichtner, P., Winkelmann, J.), Wellcome Trust Case Consortium (WTCCC),
Benyamin, B., Whitfield, J.B., Genetics of Iron Status Consortium, Pramstaller, P.P., Hicks, A.A., Thompson,
J.R., Minelli, C.°: Serum iron levels and the risk of Parkinson disease: A mendelian randomization study.
PLoS Med. 10:e1001462 (2013)
Polonikov, A.V.°, Ivanov, V.P., Bogomazov, A.D., Freidin, M.B., Illig, T., Solodilova, M.A.: Antioxidant
defense enzyme genes and asthma susceptibility: Gender-specific effects and heterogeneity in gene-gene
interactions between pathogenetic variants of the disease. Biomed Res. Int. 2014:708903 (2014)
Quinones, P.A.°, Kirchberger, I., Heier, M., Kuch, B., Trentinaglia, I., Mielck, A., Peters, A., von Scheidt,
W., Meisinger, C.: Marital status shows a strong protective effect on long-term mortality among first acute
myocardial infarction-survivors with diagnosed hyperlipidemia - findings from the MONICA/KORA Myocardial
Infarction Registry. BMC Public Health 14:98 (2014)
page 114 of 247
2015-11-23
#
joint first authors
Quinones, P.A.°, Seidl, H., Holle, R., Kuch, B., Meisinger, C., Hunger, M., Kirchberger, I.: New potential
determinants of disability in aged persons with myocardial infarction: Results from the KORINNA-study. BMC
Geriatr. 14:34 (2014)
Raedler, D., Ballenberger, N., Klucker, E., Böck, A., Otto, R., Prazeres da Costa, O., Holst, O., Illig, T.,
Buch, T., von Mutius, E., Schaub, B.°: Identification of novel immune phenotypes for allergic and nonallergic
childhood asthma. J. Allergy Clin. Immunol. 135, 81-91 (2015) [published online 2014]
Raitoharju, E.°, Seppälä, I., Oksala, N., Lyytikäinen, L.P., Raitakari, O., Viikari, J., Ala-Korpela, M., Soininen,
P., Kangas, A.J., Waldenberger, M., Klopp, N., Illig, T., Leiviskä, J., Loo, B.M., Hutri-Kähönen, N.,
Kähönen, M., Laaksonen, R., Lehtimäki, T.: Blood microRNA profile associates with the levels of serum lipids
and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways
underlying metabolic syndrome : The Cardiovascular Risk in Young Finns study. Mol. Cell. Endocrinol. 389,
41-49 (2014)
Ramin, M., Bürger, A., Hörlein, A., Kerkau, D., von Walcke-Wulffen, V., Nicklas, W., Schenkel, J.°: Stability
of cryopreserved samples of mutant mice. Biopreserv. Biobank. 12, 343-350 (2014)
Reinthaler, E.M.#, Lal, D.#, Lebon, S., Hildebrand, M.S., Dahl, H.H., Regan, B.M., Feucht, M., Steinböck, H.,
Neophytou, B., Ronen, G.M., Roche, L., Gruber-Sedlmayr, U., Geldner, J., Haberlandt, E., Hoffmann, P.,
Herms, S., Gieger, C., Waldenberger, M., Franke, A., Wittig, M., Schoch, S., Becker, A.J., Hahn, A.,
Männik, K., Toliat, M.R., Winterer, G., Lerche, H., Nürnberg, P., Mefford, H.C., Scheffer, I.E., Berkovic, S.F.,
Beckmann, J.S., EPICURE Consortium (Reymond, A.), EuroEPINOMICS Consortium (Zimprich, F.°),
Sander, T., Jacquemont, S., Neubauer, B.A.: 16p11.2 600 kb duplications confer risk for typical and atypical
Rolandic epilepsy. Hum. Mol. Genet. 23, 6069-6080 (2014)
(2014)
#
#
Rivas, M.A. , Pirinen, M. , Neville, M.J., Gaulton, K.J., Moutsianas, L., GoT2D Consortium (Gieger, C.,
M., Peters, A., Rathmann, W., Ried, J.S., Strauch, K., Donnelly, P.°), Lindgren, C.M., Karpe, F.,
McCarthy, M.I.: Assessing association between protein truncating variants and quantitative traits.
Bioinformatics 29, 2419-2426 (2013)
page 115 of 247
2015-11-23
#
joint first authors
Rohrmann, S., Linseisen, J.°, Overvad, K., Lund Würtz, A.M., Roswall, N., Tjonneland, A., Boutron-Ruault,
M.C., Racine, A., Bastide, N., Palli, D., Agnoli, C., Panico, S., Tumino, R., Sacerdote, C., Weikert, S.,
Steffen, A., Kuhn, T., Li, K., Khaw, K.T., Wareham, N.J., Bradbury, K.E., Peppa, E., Trichopoulou, A.,
Trichopoulos, D., Bueno-de-Mesquita, H.B., Peeters, P.H., Hjartåker, A., Skeie, G., Weiderpass, E., Jakszyn,
P., Dorronsoro, M., Barricarte, A., Santiuste de Pablos, C., Molina-Montes, E., de la Torre, R.A., Ericson, U.,
Sonestedt, E., Johansson, M., Ljungberg, B., Freisling, H., Romieu, I., Cross, A.J., Vergnaud, A.C., Riboli,
E., Boeing, H.: Meat and fish consumption and the risk of renal cell carcinoma in the European prospective
investigation into cancer and nutrition. Int. J. Cancer 136, E423–E431 (2015) [published online 2014]
Rückerl, R.°, Hampel, R., Breitner, S., Cyrys, J., Kraus, U., Carter, J., Dailey, L., Devlin, R.B.,
Diaz-Sanchez, D., Koenig, W., Phipps, R., Silbajoris, R., Soentgen, J., Soukup, J., Peters, A., Schneider,
A.E.: Associations between ambient air pollution and blood markers of inflammation and
coagulation/fibrinolysis in susceptible populations. Environ. Int. 70, 32-49 (2014)
Ruf, E., Baumert, J.J., Meisinger, C., Döring, A., Ladwig, K.-H.°: Are psychosocial stressors associated
with the relationship of alcohol consumption and all-cause mortality? BMC Public Health 14:312 (2014)
Schäfer, A.S.°, Bochenek, G., Jochens, A., Ellinghaus, D., Dommisch, H., Guzeldemir-Akcakana, E., Graetz,
C., Harks, I., Jockel-Schneider, Y., Weinspach, K., Meyle, J., Eickholz, P., Linden, G.J., Cine, N., Nohutcu,
R., Weiss, E., Houri-Haddad, Y., Iraqi, F., Folwaczny, M., Noack, B., Strauch, K., Gieger, C.,
Waldenberger, M., Peters, A., Wijmenga, C., Yilmaz, E., Lieb, W., Rosenstiel, P., Doerfer, C., Bruckmann,
C., Erdmann, J., König, I., Jepsen, S., Loos, B.G., Schreiber, S.: Genetic evidence for PLASMINOGEN as a
shared genetic risk factor of coronary artery disease and periodontitis. Circ. Cardiovasc. Genet. 8, 159-167
Schäffler, M., Sousa, F., Wenk, A., Sitia, L., Hirn, S., Schleh, C., Haberl, N., Violatto, M., Canovi, M.,
Andreozzi, P., Salmona, M., Bigini, P., Kreyling, W.G.°, Krol, S.°: Blood protein coating of gold nanoparticles
as potential tool for organ targeting. Biomaterials 35, 3455-3466 (2014)
#
#
#
Schieck, M. , Sharma, V. , Michel, S. , Toncheva, A.A., Worth, L., Potaczek, D.P., Genuneit, J.,
Kretschmer, A., Depner, M., Dalphin, J.C., Riedler, J., Frei, R., Pekkanen, J.J., Tost, J., Kabesch, M.°: A
polymorphism in the TH2 locus control region is associated with changes in DNA methylation and gene
expression. Allergy 69, 1171-1180 (2014)
page 116 of 247
2015-11-23
#
joint first authors
#
#
#
Schikowski, T. °, Adam, M. , Marcon, A. , Cai, Y., Vierkötter, A., Carsin, A.E., Jacquemin, B., Al Kanani, Z.,
Beelen, R., Birk, M., Bridevaux, P.O., Brunekeef, B., Burney, P., Cirach, M., Cyrys, J., de Hoogh, K., de
Marco, R., de Nazelle, A., Declercq, C., Forsberg, B., Hardy, R., Heinrich, J., Hoek, G., Jarvis, D., Keidel,
D., Kuh, D., Kuhlbusch, T., Migliore, E., Mosler, G., Nieuwenhuijsen, M.J., Phuleria, H., Rochat, T.,
Schindler, C., Villani, S., Tsai, M.Y., Zemp, E., Hansell, A., Kauffmann, F., Sunyer, J., Probst-Hensch, N.,
Krämer, U., Künzli, N.: Association of ambient air pollution with the prevalence and incidence of COPD. Eur.
Respir. J. 44, 614-626 (2014)
Schipf, S°, Ittermann, T., Tamayo, T., Holle, R., Schunk, M., Maier, W., Meisinger, C., Thorand, B., Kluttig,
A., Greiser, K.H., Berger, K., Müller, G., Moebus, S., Slomiany, U., Icks, A., Rathmann, W., Völzke, H.:
Regional differences in the incidence of self-reported type 2 diabetes in Germany: Results from five
population-based studies in Germany (DIAB-CORE Consortium) J. Epidemiol. Community Health 68,
1088-1095 (2014)
Schöttker, B.°, Jorde, R., Peasey, A., Thorand, B., Jansen, E.H.J.M., de Groot, L., Streppel, M., Gardiner,
J.R., Ordóñez-Mena, J.M., Perna, L., Wilsgaard, T., Rathmann, W., Feskens, E., Kampman, E., Siganos, G.,
Njølstad, I., Mathiesen, E.B., Kubínová, R., Pajak, A., Topor-Madry, R., Tamosiunas, A., Hughes, M., Kee,
F., Bobak, M., Trichopoulou, A., Boffetta, P., Brenner, H.: Vitamin D and mortality: Meta-analysis of individual
participant data from a large consortium of cohort studies from Europe and the United States. Br. Med. J.
348:g3656 (2014)
Schulte, E.C.#, Kousi, M.#, Tan, P.L., Tilch, E., Knauf, F., Lichtner, P., Trenkwalder, C., Högl, B.,
Frauscher, B., Berger, K., Fietze, I., Hornyak, M., Oertel, W.H., Bachmann, C.G., Zimprich, A., Peters, A.,
Gieger, C., Meitinger, T., Müller-Myhsok, B., Katsanis, N., Winkelmann, J.°: Targeted resequencing and
systematic in vivo functional testing identifies rare variants in MEIS1 as significant contributors to restless
legs syndrome. Am. J. Hum. Genet. 95, 85-95 (2014)
Seibold, P., Vrieling, A., Johnson, T.S., Buck, K., Behrens, S., Kaaks, R., Linseisen, J., Obi, N., Heinz, J.,
Flesch-Janys, D., Chang-Claude, J.°: Enterolactone concentrations and prognosis after postmenopausal
breast cancer: Assessment of effect modification and meta-analysis. Int. J. Cancer 135, 923-933 (2014)
page 117 of 247
2015-11-23
#
joint first authors
Seidl, H.°, Hunger, M., Leidl, R., Meisinger, C., Wende, R., Kuch, B., Holle, R.: Cost-effectiveness of
nurse-based case management versus usual care for elderly patients with myocardial infarction: Results
from the KORINNA study. Eur. J. Health Econ. 16, 671-681 (2015) [published online 2014]
Semmler-Behnke, M., Lipka, J., Wenk, A., Hirn, S., Schäffler, M., Tian, F., Schmid, G., Oberdörster, G.,
Kreyling, W.G.°: Size dependent translocation and fetal accumulation of gold nanoparticles from maternal
blood in the rat. Part. Fibre Toxicol. 11:33 (2014)
Sharma, V., Michel, S., Gaertner, V., Franke, A., Vogelberg, C., von Berg, A., Bufe, A., Heinzmann, A., Laub,
O., Rietschel, E., Simma, B., Frischer, T.H., Genuneit, J., Zeilinger, S., Illig, T., Schedel, M., Potaczek, D.P.,
Kabesch, M.°: Fine-mapping of IgE-associated loci 1q23, 5q31, and 12q13 using 1000 Genomes Project
data. Allergy 69, 1077-1084 (2014)
(2014)
#
#
#
#
Shin, S.Y. , Fauman, E.B. , Petersen, A.-K. , Krumsiek, J. , Santos, R., Huang, J., Arnold, M., Erte, I.,
Nat. Genet. 46, 543-550 (2014)
Simkó, M.°, Nosske, D., Kreyling, W.G.: Metrics, dose, and dose concept: The need for a proper dose
concept in the risk assessment of nanoparticles. Int. J. Environ. Res. Public Health 11, 4026-4048 (2014)
ONE 9:e107110 (2014)
page 118 of 247
2015-11-23
#
joint first authors
#
#
#
#
#
#
#
#
Sinner, M.F. , Tucker, N.R. , Lunetta, K.L. , Ozaki, K. , Smith, J.G. , Trompet, S. , Bis, J.C. , Lin, H. , Chung,
#
#
#
#
#
M.K. , Nielsen, J.B. , Lubitz, S.A. , Krijthe, B.P. , Magnani, J.W. , Ye, J., Gollob, M.H., Tsunoda, T.,
Müller-Nurasyid, M., Lichtner, P., Peters, A., Dolmatova, E., Kubo, M., Smith, J.D., Psaty, B.M., Smith,
N.L., Jukema, J.W., Chasman, D.I., Albert, C.M., Ebana, Y., Furukawa, T., Macfarlane, P.W., Harris, T.B.,
Darbar, D., Dörr, M., Holst, A.G., Svendsen, J.H., Hofman, A., Uitterlinden, A., Gudnason, V., Isobe, M.,
Malik, R., Dichgans, M., Rosand, J., van Wagoner, D.R., METASTROKE Consortium (Kääb, S.), AFGen
Consortium (Ellinor, P.T.°), Benjamin, E.J., Milan, D.J., Melander, O., Heckbert, S.R, Ford, I., Liu, Y.,
Barnard, J., Olesen, M.S., Stricker, B.H., Tanaka, T.: Integrating genetic, transcriptional, and functional
analyses to identify five novel genes for atrial fibrillation. Circulation 130, 1225-1235 (2014)
#
#
Spyroglou, A. , Bozoglu, T. , Rawal, R., de Leonardis, F., Sterner, C., Boulkroun, S., Benecke, A.G., Monti,
L., Zennaro, M.C., Petersen, A.-K., Döring, A., Rossi, A., Bidlingmaier, M., Warth, R., Gieger, C., Reincke,
#
#
M. , Beuschlein, F. °: Diastrophic dysplasia sulfate transporter (SLC26A2) is expressed in the adrenal cortex
and regulates aldosterone secretion. Hypertension 63, 1102-1109 (2014)
Stafoggia, M., Cesaroni, G., Peters, A., Andersen, Z.J., Badaloni, C., Beelen, R., Caracciolo, B., Cyrys, J.,
de Faire, U., de Hoogh, K., Eriksen, K.T., Fratiglioni, L., Galassi, C., Gigante, B., Havulinna, A.S., Hennig, F.,
Hilding, A., Hoek, G., Hoffmann, B., Houthuijs, D., Korek, M., Lanki, T., Leander, K., Magnusson, P.K.,
Meisinger, C., Migliore, E., Overvad, K., Ostenson, C.G., Pedersen, N.L., Pekkanen, J., Penell, J.,
Pershagen, G., Pundt, N., Pyko, A., Raaschou-Nielsen, O., Ranzi, A., Ricceri, F., Sacerdote, C., Swart, W.J.,
Turunen, A.W., Vineis, P., Weimar, C., Weinmayr, G., Wolf, K., Brunekreef, B., Forastiere, F.°: Long-term
exposure to ambient air pollution and incidence of cerebrovascular events: Results from 11 European
cohorts within the ESCAPE project. Environ. Health Perspect. 122, 919-925 (2014)
Stang, A.°, Kluttig, A., Moebus, S., Völzke, H., Berger, K., Greiser, K.H., Stöckl, D., Jockel, K.H., Meisinger,
C.: Educational level, prevalence of hysterectomy, and age at amenorrhoea: A cross-sectional analysis of
9536 women from six population-based cohort studies in Germany. BMC Womens Health 14:10 (2014)
Starkbaum, J.°, Gottweis, H., Gottweis, U., Kleiser, C., Linseisen, J., Meisinger, C., Kamtsiuris, P.,
Moebus, S., Jockel, K.H., Boerm, S., Wichmann, H.-E.: Public perceptions of cohort studies and biobanks in
Germany. Biopreserv. Biobank. 12, 121-130 (2014)
(2014)
page 119 of 247
2015-11-23
#
joint first authors
#
#
#
Stratmann, B. , Xu, T. , Meisinger, C. , Menart, B., Roden, M., Herder, C., Grallert, H., Peters, A., Koenig,
W., Illig, T., Wichmann, H.-E., Wang-Sattler, R., Rathmann, W., Tschoepe, D.°: PLA1A2 platelet
polymorphism predicts mortality in prediabetic subjects of the population based KORA S4-cohort.
Cardiovasc. Diabetol. 13:90 (2014)
Strobl, R.°, Müller, M., Thorand, B., Linkohr, B., Autenrieth, C.S., Peters, A., Grill, E.: Men benefit more
from midlife leisure-time physical activity than women regarding the development of late-life disability results of the KORA-Age study. Prev. Med. 62, 8-13 (2014)
Struja, T., Richard, A., Linseisen, J., Eichholzer, M., Rohrmann, S.°: The association between urinary
phytoestrogen excretion and components of the metabolic syndrome in NHANES. Eur. J. Nutr. 53,
1371-1381 (2013)
Szafranski, S.P., Wos-Oxley, M.L., Vilchez-Vargas, R., Jáuregui, R., Plumeier, I., Klawonn, F., Tomasch, J.,
Meisinger, C., Kühnisch, J., Sztajer, H., Pieper, D.H., Wagner-Döbler, I.°: High resolution taxonomic profiling
of the subgingival microbiome for biomarker discovery and periodontitis diagnosis. Appl. Environ. Microbiol.
Tamayo, T.°, Schipf, S., Meisinger, C., Schunk, M., Maier, W., Herder, C., Roden, M., Nauck, M., Peters,
A., Völzke, H., Rathmann, W.: Regional differences of undiagnosed type 2 diabetes and prediabetes
prevalence are not explained by known risk factors. PLoS ONE 9:e113154 (2014)
#
#
#
#
TG and HDL Working Group (Crosby, J.R. , Peloso, G.M. , Auer, P.L. , Peters, A., Reiner, A.P. ,
#
Boerwinkle, E. , Kathiresan, S.°): Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
N. Engl. J. Med. 371, 22-31 (2014)
Thaler-Kall, K.°, Döring, A., Peters, A., Thorand, B., Grill, E., Koenig, W., Horsch, A., Meisinger, C.:
Association between anemia and falls in community-dwelling older people: Cross-sectional results from the
KORA-Age study. BMC Geriatr. 14:29 (2014)
page 120 of 247
2015-11-23
#
joint first authors
#
#
#
Tragante, V. , Barnes, M.R. , Ganesh, S.K. , Lanktree, M.B., Guo, W., Franceschini, N., Smith, E.N.,
Johnson, T., Holmes, M.V., Padmanabhan, S., Karczewski, K.J., Almoguera, B., Barnard, J., Baumert, J.J.,
Chang, Y.-P., Elbers, C.C., Farrall, M., Fischer, M.E., Gaunt, T.R., Gho, J.M.I.H., Gieger, C., Goel, A., Gong,
Y., Isaacs, A., Kleber, M.E., Leach, I.M., McDonough, C.W., Meijs, M.F.L., Melander, O., Nelson, C.P., Nolte,
I.M., Pankratz, N., Price, T.S., Shaffer, J., Shah, S., Tomaszewski, M., van der Most, P.J., Van Iperen,
E.P.A., Vonk, J.M., Witkowska, K., Wong, C.O.L., Zhang, L., Beitelshees, A.L., Berenson, G.S., Bhatt, D.L.,
Brown, M., Burt, A., Cooper-DeHoff, R.M., Connell, J.M., Cruickshanks, K.J., Curtis, S.P., Davey-Smith, G.,
Delles, C., Gansevoort, R.T., Guo, X., Haiqing, S., Hastie, C.E., Hofker, M.H., Hovingh, G.K., Kim, D.S.,
Kirkland, S.A., Klein, B.E., Klein, R., Li, Y.R., Maiwald, S., Newton-Cheh, C., O'Brien, E.T., Onland-Moret,
N. ., Palmas, W., Parsa, A., Penninx, B.W., Pettinger, M., Vasan, R.S., Ranchalis, J.E., Ridker, P.M., Rose,
L.M., Sever, P., Shimbo, D., Steele, L., Stolk, R.P., Thorand, B., Trip, M.D., van Duijn, C.M., Verschuren,
W.M., Wijmenga, C., Wyatt, S., Young, J., Zwinderman, A.H., Bezzina, C.R., Boerwinkle, E., Casas, J.P.,
Caulfield, M.J., Chakravarti, A., Chasman, D.I., Davidson, K.W., Doevendans, P.A., Dominiczak, A.F.,
Fitzgerald, G.A., Gums, J.G., Fornage, M., Hakonarson, H., Halder, I., Hillege, H.L., Illig, T., Jarvik, G.P.,
Johnson, J.A., Kastelein, J.J.P., Koenig, W., Kumari, M., Marz, W., Murray, S.S., O'Connell, J.R., Oldehinkel,
A.J., Pankow, J.S., Rader, D.J., Redline, S., Reilly, M.P., Schadt, E.E., Kottke-Marchant, K., Snieder, H.,
Snyder, M., Stanton, A.V., Tobin, M.D., Uitterlinden, A.G., van der Harst, P., van der Schouw, Y.T., Samani,
N.J., Watkins, H., Johnson, A.D., Reiner, A.P., Zhu, X., de Bakker, P.I.W., Levy, D., Asselbergs, F.W.,
Munroe, P.B.°, Keating, B.J.°: Gene-centric meta-analysis in 87,736 individuals of European ancestry
identifies multiple blood-pressure-related loci. Am. J. Hum. Genet. 94, 349-360 (2014)
Tsepilov, Y.A., Ried, J.S., Strauch, K., Grallert, H., van Duijn, C.M., Axenovich, T.I., Aulchenko, Y.S.°:
Development and application of genomic control methods for genome-wide association studies using
non-additive models. PLoS ONE 8:e81431 (2013)
#
#
#
#
#
van der Valk, R.J. , Kreiner-Møller, E. , Kooijman, M.N. , Guxens, M. , Stergiakouli, E. , Saaf, A., Bradfield,
J.P., Geller, F., Hayes, M.G., Cousminer, D.L., Körner, A., Thiering, E., Curtin, J.A., Myhre, R., Huikari, V.,
Joro, R., Kerkhof, M., Warrington, N.M., Pitkänen, N., Ntalla, I., Horikoshi, M., Veijola, R., Freathy, R.M., Teo,
Y.Y., Barton, S.J., Evans, D.M., Kemp, J.P., St Pourcain, B., Ring, S.M., Smith, G.D., Bergström, A., Kull, I.,
Hakonarson, H., Mentch, F.D., Bisgaard, H., Chawes, B., Stokholm, J., Waage, J., Eriksen, P., Sevelsted, A.,
Melbye, M., van Duijn, C.M., Medina-Gomez, C., Hofman, A., de Jongste, J.C., Taal, H.R., Uitterlinden, A.G.,
Armstrong, L.L., Eriksson, J., Palotie, A., Bustamante, M., Estivill, X., Gonzalez, J.R., Llop, S., Kiess, W.,
Mahajan, A., Flexeder, C., Tiesler, C.M., Murray, C.S., Simpson, A., Magnus, P., Sengpiel, V., Hartikainen,
A.L., Keinanen-Kiukaanniemi, S., Lewin, A., da Silva Couto Alves, A., Blakemore, A.I., Buxton, J.L.,
Kaakinen, M., Rodriguez, A., Sebert, S., Vaarasmaki, M., Lakka, T., Lindi, V., Gehring, U., Postma, D.S.,
Ang, W., Newnham, J.P., Lyytikäinen, L.P., Pahkala, K., Raitakari, O.T., Panoutsopoulou, K., Zeggini, E.,
Boomsma, D.I., Groen-Blokhuis, M., Ilonen, J., Franke, L., Hirschhorn, J.N., Pers, T.H., Liang, L., Huang, J.,
Hocher, B., Knip, M., Saw, S.M., Holloway, J.W., Melén, E., Grant, S.F., Feenstra, B., Lowe, W.L., Widen, E.,
Sergeyev, E., Grallert, H., Custovic, A., Jacobsson, B., Jarvelin, M.R., Atalay, M., Koppelman, G.H., Pennell,
C.E., Niinikoski, H., Dedoussis, G.V., McCarthy, M.I., Frayling, T.M., Sunyer, J., Timpson, N.J., Rivadeneira,
F., Bønnelykke, K., Jaddoe, V.W.°: A novel common variant in DCST2 is associated with length in early life
and height in adulthood. Hum. Mol. Genet. 24, 1155-1168 (2015) [published online 2014]
page 121 of 247
2015-11-23
#
joint first authors
#
#
#
#
van Vliet-Ostaptchouk, J.V. , Nuotio, M.L. , Slagter, S.N. , Doiron, D. , Fischer, K., Foco, L., Gaye, A.,
Gögele, M., Heier, M., Hiekkalinna, T., Joensuu, A., Newby, C., Pang, C.P., Partinen, E., Reischl, E.,
Schwienbacher, C., Tammesoo, M.L., Swertz, M.A., Burton, P.R, Ferretti, V., Fortier, I., Giepmans, L., Harris,
J.R., Hillege, H.L., Holmen, J., Jula, A., Kootstra-Ros, J.E., Kvaløy, K., Holmen, T.L., Männisto, S., Metspalu,
A., Midthjell, K., Murtagh, M.J., Peters, A., Pramstaller, P.P., Saaristo, T., Salomaa, V., Stolk, R.P.,
Uusitupa, M., van der Harst, P., van der Klauw, M.M., Waldenberger, M., Perola, M., Wolffenbuttel, B.H.°:
The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: A collaborative analysis
of ten large cohort studies. BMC Endocr. Disord. 14:9 (2014)
von Eisenhart Rothe, A., Goette, A., Kirchhof, P., Breithardt, G., Limbourg, T., Calvert, M., Baumert, J.J.,
Ladwig, K.-H.°: Depression in paroxysmal and persistent atrial fibrillation patients: A cross-sectional
comparison of patients enroled in two large clinical trials. Europace 16, 812-819 (2014)
15:232 (2014)
Walsh, K.M.°, Codd, V., Smirnov, I.V., Rice, T., Decker, P.A., Hansen, H.M., Kollmeyer, T., Kosel, M.L.,
Molinaro, A.M., McCoy, L.S., Bracci, P.M., Cabriga, B.S., Pekmezci, M., Zheng, S., Wiemels, J.L., Pico, A.R.,
Tihan, T., Berger, M.S., Chang, S.M., Prados, M.D., Lachance, D.H., O'Neill, B.P., Sicotte, H.,
Eckel-Passow, J.E., ENGAGE Consortium Telomere Group (Albrecht, E., Klopp, N., Peters, A.,
Wichmann, H.-E., Gieger, C.), van der Harst, P., Wiencke, J.K., Samani, N.J., Jenkins, R.B., Wrensch,
M.R.: Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.
Nat. Genet. 46, 731-735 (2014)
Wang, M.°, Beelen, R., Stafoggia, M., Raaschou-Nielsen, O., Andersen, Z.J., Hoffmann, B., Fischer, P.,
Houthuijs, D., Nieuwenhuijsen, M., Weinmayr, G., Vineis, P., Xun, W.W., Dimakopoulou, K., Samoli, E.,
Laatikainen, T., Lanki, T., Turunen, A.W., Oftedal, B., Schwarze, P., Aamodt, G., Penell, J., de Faire, U.,
Korek, M., Leander, K., Pershagen, G., Pedersen, N.L., Ostenson, C.G., Fratiglioni, L., Eriksen, K.T.,
Sørensen, M., Tjønneland, A., Bueno-de-Mesquita, B., Eeftens, M., Bots, M.L., Meliefste, K., Krämer, U.,
Heinrich, J., Sugiri, D., Key, T., de Hoogh, K., Wolf, K., Peters, A., Cyrys, J., Jaensch, A., Concin, H.,
Nagel, G., Tsai, M.Y., Phuleria, H., Ineichen, A., Künzli, N., Probst-Hensch, N., Schaffner, E., Vilier, A.,
Clavel-Chapelon, F., Declerq, C., Ricceri, F., Sacerdote, C., Marcon, A., Galassi, C., Migliore, E., Ranzi, A.,
Cesaroni, G., Badaloni, C., Forastiere, F., Katsoulis, M., Trichopoulou, A., Keuken, M., Jedynska, A., Kooter,
I.M., Kukkonen, J.V.K., Sokhi, R.S., Brunekreef, B., Katsouyanni, K., Hoek, G.: Long-term exposure to
elemental constituents of particulate matter and cardiovascular mortality in 19 European cohorts: Results
from the ESCAPE and TRANSPHORM projects. Environ. Int. 66, 97-106 (2014)
page 122 of 247
2015-11-23
#
joint first authors
Wang, M.°, Beelen, R., Bellander, T., Birk, M., Cesaroni, G., Cirach, M., Cyrys, J., de Hoogh, K., Declercq,
C., Dimakopoulou, K., Eeftens, M., Eriksen, K.T., Forastiere, F., Galassi, C., Grivas, G., Heinrich, J.,
Hoffmann, B., Ineichen, A., Korek, M., Lanki, T., Lindley, S., Modig, L., Mölter, A., Nafstad, P.,
Nieuwenhuijsen, M.J., Nystad, W., Olsson, D., Raaschou-Nielsen, O., Ragettli, M., Ranzi, A., Stempfelet, M.,
Sugiri, D., Tsai, M.Y., Udvardy, O., Varró, M.J., Vienneau, D., Weinmayr, G., Wolf, K., Yli-Tuomi, T., Hoek,
G., Brunekreef, B.: Performance of multi-city land use regression models for nitrogen dioxide and fine
particles. Environ. Health Perspect. 122, 843-849 (2014)
Am. J. Hum. Genet. 94, 710-720 (2014)
Wawro, N., Heinrich, J., Thiering, E., Kratzsch, J., Schaaf, B., Hoffmann, B., Lehmann, I., Bauer, C.P.,
Koletzko, S., von Berg, A., Berdel, D., Linseisen, J.°: Serum 25(OH)D concentrations and atopic diseases at
age 10: Results from the GINIplus and LISAplus birth cohort studies. BMC Pediatr. 14:286 (2014)
Weidenhammer, W.°, Lacruz, M.E., Emeny, R.T., Linde, K., Peters, A., Thorand, B., Mielck, A., Ladwig,
K.-H.: Prevalence of use and level of awareness of CAM in older people - results from the KORA-Age study.
Forsch. Komplementmed. 21, 294-301 (2014)
#
#
Wieczorek, D. °, Newman, W.G. , Wieland, T., Berulava, T., Kaffe, M., Falkenstein, D., Beetz, C., Graf, E.,
Schwarzmayr, T., Douzgou, S., Clayton-Smith, J., Daly, S.B., Williams, S.G., Bhaskar, S.S., Urquhart, J.E.,
Anderson, B., O'Sullivan, J., Boute, O., Gundlach, J., Czeschik, J.C., van Essen, A.J., Hazan, F., Park, S.,
Hing, A., Kuechler, A., Lohmann, D.R., Ludwig, K.U., Mangold, E., Steenpaß, L., Zeschnigk, M., Lemke, J.R.,
Lourenco, C.M., Hehr, U., Prott, E.C., Waldenberger, M., Böhmer, A.C., Horsthemke, B., O'Keefe, R.T.,
Meitinger, T., Burn, J., Lüdecke, H.J., Strom, T.M.: Compound heterozygosity of low-frequency promoter
deletions and rare loss-of-function mutations in TXNL4A causes Burn-McKeown syndrome. Am. J. Hum.
Genet. 95, 698-707 (2014)
Winkler, T.W., Day, F.R., Croteau-Chonka, D.C., Wood, A.R., Locke, A.E., Mägi, R., Ferreira, T., Fall, T.,
Graff, M., Justice, A.E., Luan, J., Gustafsson, S., Randall, J.C., Vedantam, S., Workalemahu, T., Kilpeläinen,
T.O., Scherag, A., Esko, T., Kutalik, Z., Heid, I.M.°, Loos, R.J.°, GIANT Consortium (Albrecht, E.,
Müller-Nurasyid, M., Grallert, H., Peters, A., Thorand, B., Gieger, C., Illig, T., Wichmann, H.-E.): Quality
control and conduct of genome-wide association meta-analyses. Nat. Protoc. 9, 1192-1212 (2014)
Winkler, V.°, Leitzmann, M., Obi, N., Ahrens, W., Edinger, T., Giani, G., Linseisen, J., Löffler, M., Michels,
K., Nöthlings, U., Schipf, S., Kluttig, A., Wichmann, H.-E., Hoffmann, B., Jockel, K.H., Becher, H.: Response
in individuals with and without foreign background and application to the National Cohort in Germany: Which
factors have an effect? Int. J. Public Health 59, 555-563 (2014)
page 123 of 247
2015-11-23
#
joint first authors
page 124 of 247
2015-11-23
#
joint first authors
height. Nat. Genet. 46, 1173-1186 (2014)
Xi, B., Takeuchi, F., Meirhaeghe, A., Kato, N., Chambers, J.C., Morris, A.P., Cho, Y.S., Zhang, W., Mohlke,
K.L., Kooner, J.S., Shu, X.O., Pan, H., Tai, E.S., Pan, H., Wu, J., Zhou, D.°, Chandak, G.R., DIAGRAM
Consortium (Gieger, C., Grallert, H., Illig, T., Klopp, N., Müller-Nurasyid, M., Peters, A.), AGEN-T2D
Consortium, SAT2D Consortium: Associations of genetic variants in/near body mass index-associated genes
with type 2 diabetes: A systematic meta-analysis. Clin. Endocrinol. 81, 702-710 (2014)
#
#
#
#
Yoneyama, S. , Guo, Y. , Lanktree, M.B. , Barnes, M.R. , Elbers, C.C., Karczewski, K.J., Padmanabhan, S.,
2498-2510 (2014)
page 125 of 247
2015-11-23
#
joint first authors
Zebhauser, A., Baumert, J.J., Emeny, R.T., Ronel, J., Peters, A., Ladwig, K.-H.°: What prevents old
people living alone from feeling lonely? Findings from the KORA-Age-study. Aging Ment. Health 19, 773-780
Zech, M.#, Castrop, F.#, Schormair, B., Jochim, A., Wieland, T., Gross, N., Lichtner, P., Peters, A.,
Gieger, C., Meitinger, T., Strom, T.M., Oexle, K., Haslinger, B.°, Winkelmann, J.°: DYT16 revisited:
Exome sequencing identifies PRKRA mutations in a European dystonia family. Mov. Disord. 29, 1504-1510
(2014)
Zech, M., Nübling, G., Castrop, F., Jochim, A., Schulte, E.C., Mollenhauer, B., Lichtner, P., Peters, A.,
Gieger, C., Marquardt, T., Vanier, M.T., Latour, P., Klünemann, H.H., Trenkwalder, C., Diehl-Schmid, J.,
Perneczky, R., Meitinger, T., Oexle, K., Haslinger, B., Lorenzl, S., Winkelmann, J.°: Niemann-pick C
disease gene mutations and age-related neurodegenerative disorders. PLoS ONE 8:e82879 (2013)
Zeller, T.#°, Hughes, M.#, Tuovinen, T., Schillert, A., Conrads-Frank, A., Ruijter, H.D., Schnabel, R.B., Kee,
F., Salomaa, V., Siebert, U., Thorand, B., Ziegler, A., Breek, H., Pasterkamp, G., Kuulasmaa, K., Koenig,
W., Blankenberg, S.°: BiomarCaRE: Rationale and design of the European BiomarCaRE project including
300,000 participants from 13 European countries. Eur. J. Epidemiol. 29, 777-790 (2014)
page 126 of 247
2015-11-23
#
joint first authors
Institute of Experimental Genetics
+
+
-
Arndt, B.°, Witkowski, L., Ellwart, J.W., Seissler, J.: CD8 CD122 PD-1 effector cells promote the
Blanco, S., Dietmann, S., Flores, J.V., Hussain, S., Kutter, C., Humphreys, P., Lukk, M., Lombard, P., Treps,
L., Popis, M., Kellner, S., Hölter, S.M., Garrett, L., Wurst, W., Becker, L., Klopstock, T., Fuchs, H.,
Gailus-Durner, V., Hrabě de Angelis, M., Káradóttir, R.T., Helm, M., Ule, J., Gleeson, J.G., Odom, D.T.,
Frye, M.°: Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders. EMBO J.
33, 2020-2039 (2014)
9:e93148 (2014)
#
#
Dunkel, J. , Aguilar-Pimentel, J.A. , Ollert, M., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis, M.,
Jalkanen, S., Salmi, M., Veres, T.Z.°: Endothelial amine oxidase AOC3 transiently controbutes to adaptive
immune responses in the airways. Eur. J. Immunol. 44, 3232-3239 (2014)
Ehninger, D.°, Neff, F., Xie, K.: Longevity, aging and rapamycin. Cell. Mol. Life Sci. 71, 4325-4346 (2014)
page 127 of 247
2015-11-23
#
joint first authors
Horsch, M., Beckers, J., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis, M., Rathkolb, B., Wolf, E.,
Aigner, B., Kemter, E.°: Uromodulin retention in thick ascending limb of Henle's loop affects SCD1 in
neighboring proximal tubule: Renal transcriptome studies in mouse models of uromodulin-associated kidney
disease. PLoS ONE 9:e113125 (2014)
INFRAFRONTIER Consortium (de Castro, A., Fessele, S., Steinkamp, R., Hagn, M., Raess, M., Hrabě de
Angelis, M., Meehan, T.F.°): INFRAFRONTIER - providing mutant mouse resources as research tools for
the international scientific community. Nucleic Acids Res. 53, D1171-D1175 (2015) [published online 2014]
Clin. Nutr. 100, 891-900 (2014)
#
#
John-Schuster, G. , Hager, K. , Conlon, T.M., Irmler, M., Beckers, J., Eickelberg, O., Yildirim, A.Ö.°:
Karp, N.A.°, Speak, A.O., White, J.K., Adams, D.J., Hrabě de Angelis, M., Herault, Y., Mott, R.F.: Impact of
temporal variation on design and analysis of mouse knockout phenotyping studies. PLoS ONE 9:e111239
(2014)
2014]
page 128 of 247
2015-11-23
#
joint first authors
Kemter, E.#°, Sklenak, S.#, Rathkolb, B., Hrabě de Angelis, M., Wolf, E., Aigner, B., Wanke, R.: No
amelioration of uromodulin maturation and trafficking defect by sodium-4-phenylbutyrate in vivo: Studies in
mouse models of uromodulin-associated kidney disease. J. Biol. Chem. 289, 10715-10726 (2014)
I299F
Keyhani-Nejad, F., Irmler, M., Isken, F., Wirth, E.K., Beckers, J., Birkenfeld, A.L., Pfeiffer, A.F.H.°:
Nutritional strategy to prevent fatty liver and insulin resistance independent from obesity by reducing
glucose-dependent insulinotropic polypeptide responses in mice. Diabetologia 58, 374-383 (2015) [published
online 2014]
#
#
PLoS ONE 9:e104568 (2014)
page 129 of 247
2015-11-23
#
joint first authors
Natl. Acad. Sci. U.S.A. 111, 13127-13132 (2014)
Mishra, A., Traut, M.H., Becker, L., Klopstock, T., Stein, V., Klein, R.°: Genetic evidence for the adhesion
protein IgSF9/Dasm1 to regulate inhibitory synapse development independent of its intracellular domain. J.
Neurosci. 34, 4187-4199 (2014)
Mullen, W.°, Saigusa, D., Abe, T., Adamski, J., Mischak, H.: Proteomics and metabolomics as tools to
unravel novel culprits and mechanisms of uremic toxicity: Instrument or hype? Semin. Nephrol. 34, 180-190
(2014)
page 130 of 247
2015-11-23
#
joint first authors
Patrício, P., Mateus-Pinheiro, A., Irmler, M., Alves, N.D., Machado-Santos, A.R., Morais, M., Correia, J.S.,
Korostynski, M., Piechota, M., Stoffel, R., Beckers, J., Bessa, J.M., Almeida, O.F., Sousa, N.°, Pinto, L.°:
Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate
gyrus. Neuropsychopharmacol. 40, 338-349 (2015) [published online 2014]
(2014)
DJ-1. J. Proteome Res. 13, 2339-2351 (2014)
Rabenstein, H.#, Behrendt, A.C.#, Ellwart, J.W., Naumann, R., Horsch, M., Beckers, J., Obst, R.°:
Differential kinetics of antigen dependency of CD4+ and CD8+ T cells. J. Immunol. 192, 3507-3517 (2014)
#
#
Rosemann, M.°, Gonzalez-Vasconcellos, I., Domke, T., Kuosaite, V., Schneider, R., Kremer, M., Favor,
J., Nathrath, M., Atkinson, M.J.: A Rb1 promoter variant with reduced activity contributes to osteosarcoma
susceptibility in irradiated mice. Mol. Cancer 13:182 (2014)
Rozman, J.°, Klingenspor, M., Hrabě de Angelis, M.: A review of standardized metabolic phenotyping of
animal models. Mamm. Genome 25, 497-507 (2014)
page 131 of 247
2015-11-23
#
joint first authors
#
#
(2014)
Sinreih, M., Anko, M., Zukunft, S., Adamski, J., Lanisnik Rizner, T.°: Important roles of the AKR1C2 and
SRD5A1 enzymes in progesterone metabolism in endometrial cancer model cell lines. Chem. Biol. Interact.
234, 297-308 (2014)
#
#
#
(2014)
#
#
#
2293-2303 (2014)
Tiedemann, H.B., Schneltzer, E., Zeiser, S., Wurst, W., Beckers, J., Przemeck, G.K.H., Hrabě de
Angelis, M.°: Fast synchronization of ultradian oscillators controlled by Delta-Notch signaling with
Cis-inhibition. PLoS Comput. Biol. 10:e1003843 (2014)
page 132 of 247
2015-11-23
#
joint first authors
(2014)
Am. J. Hum. Genet. 94, 710-720 (2014)
Wientzek, A.°, Floegel, A., Knüppel, S., Vigl, M., Drogan, D., Adamski, J., Pischon, T., Boeing, H.: Serum
metabolites related to cardiorespiratory fitness, physical activity energy expenditure, sedentary time and
vigorous activity. Int. J. Sport Nutr. Exerc. Metab. 24, 215-226 (2014)
Yan, X., Sabrautzki, S., Horsch, M., Fuchs, H., Gailus-Durner, V., Beckers, J., Hrabě de Angelis, M.,
Graw, J.°: Peroxidasin is essential for eye development in the mouse. Hum. Mol. Genet. 23, 5597-5614
(2014)
Zimprich, A., Garett, L., Deussing, J.M., Wotjak, C.T., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis,
M., Wurst, W., Hölter, S.M.°: A robust and reliable non-invasive test for stress responsivity in mice. Front.
Behav. Neurosci. 8:125 (2014)
(2014)
page 133 of 247
2015-11-23
#
joint first authors
Institute of Genetic Epidemiology
Altmaier, E.M.°, Emeny, R.T.: Use of metabolomics and proteomics to reveal pathophysiological pathways
in anxiety disorders. Adv. Biol. Psychiatry 29, 128-138 (2014)
page 134 of 247
2015-11-23
#
joint first authors
#
#
page 135 of 247
2015-11-23
#
joint first authors
(2014)
Broer, L.#°, Raschenberger, J.#, Deelen, J.#, Mangino, M., Codd, V., Pietiläinen, K.H., Albrecht, E., Amin, N.,
Budin-Ljosne, I.°, Isaeva, J., Knoppers, B.M., Tassé, A.M., Shen, H.Y., McCarthy, M., ENGAGE Consortium
(Döring, A., Gieger, C., Nitz, B., Rawal, R., Wichmann, H.-E.), Harris, J.M.: Data sharing in large research
consortia: Experiences and recommendations from ENGAGE. Eur. J. Hum. Genet. 22, 317-321 (2014)
Chan, Y., Lim, E.T., Sandholm, N., Wang, S.R., McKnight, A.J., Ripke, S., DIAGRAM Consortium (Gieger,
C., Grallert, H., Illig, T., Klopp, N., Müller-Nurasyid, M., Peters, A.), GENIE Consortium, IIBDGC
Consortium, GIANT Consortium (Albrecht, E., Heid, I.M., Thorand, B., Wichmann, H.-E.), Daly, M.J.,
Neale, B.M., Salem, R.M., Hirschhorn, J.N.°: An excess of risk-increasing low-frequency variants can be a
signal of polygenic inheritance in complex diseases. Am. J. Hum. Genet. 94, 437-452 (2014)
(2014)
page 136 of 247
2015-11-23
#
joint first authors
234-244 (2014)
1990-1998 (2014)
357-363 (2014)
9:e105116 (2014)
page 137 of 247
2015-11-23
#
joint first authors
#
#
#
#
#
#
#
#
95, 49-65 (2014)
Gong, G., Quante, A.S., Terry, M.B., Whittemore, A.S.°: Assessing the goodness of fit of personal risk
models. Stat. Med. 33, 3179-3190 (2014)
Gorski, M., Tin, A., Garnaas, M., McMahon, G.M., Chu, A.Y., Tayo, B.O., Pattaro, C., Teumer, A., Chasman,
D.I., Chalmers, J., Hamet, P., Tremblay, J., Woodward, M., Aspelund, T., Eiriksdottir, G., Gudnason, V.,
Harris, T.B., Launer, L.J., Smith, A.V., Mitchell, B.D., O'Connell, J.R., Shuldiner, A.R., Coresh, J., Li, M.,
Freudenberger, P., Hofer, E., Schmidt, H., Schmidt, R., Holliday, E.G., Mitchell, P., Wang, J.J., de Boer, I.H.,
Li, G., Siscovick, D.S., Kutalik, Z., Corre, T., Vollenweider, P., Waeber, G., Gupta, J., Kanetsky, P.A.,
Hwang, S.J., Olden, M., Yang, Q., de Andrade, M., Atkinson, E.J., Kardia, S.L., Turner, S.T., Stafford, J.M.,
Ding, J., Liu, Y., Barlassina, C., Cusi, D., Salvi, E., Staessen, J.A., Ridker, P.M., Grallert, H., Meisinger, C.,
Müller-Nurasyid, M., Krämer, B.K., Kramer, H., Rosas, S.E., Nolte, I.M., Penninx, B.W., Snieder, H., Fabiola
Del Greco, M., Franke, A., Nöthlings, U., Lieb, W., Bakker, S.J., Gansevoort, R.T., van der Harst, P.,
Dehghan, A., Franco, O.H., Hofman, A., Rivadeneira, F., Sedaghat, S., Uitterlinden, A.G., Coassin, S., Haun,
M., Kollerits, B., Kronenberg, F., Paulweber, B., Aumann, N., Endlich, K., Pietzner, M., Völker, U., Rettig, R.,
Chouraki, V., Helmer, C., Lambert, J.C., Metzger, M., Stengel, B., Lehtimäki, T., Lyytikäinen, L.P., Raitakari,
O., Johnson, A., Parsa, A., Bochud, M., Heid, I.M., Goessling, W., Köttgen, A., Kao, W.H., Fox, C.S., Böger,
C.A.°: Genome-wide association study of kidney function decline in individuals of European descent. Kidney
Int. 87, 1017–1029 (2015) [published online 2014]
Gorski, M., Winkler, T.W., Stark, K., Müller-Nurasyid, M., Ried, J.S., Grallert, H., Weber, B.H.F., Heid,
I.M.°: Harmonization of study and reference data by PhaseLift: Saving time when imputing study data.
Genet. Epidemiol. 38, 381-388 (2014)
Grassmann, F., Heid, I.M., Weber, B.H.F.°: Genetic risk models in age-related macular degeneration. Adv.
Exp. Med. Biol. 801, 291-300 (2014)
page 138 of 247
2015-11-23
#
joint first authors
#
#
#
4343-4359 (2014)
J. Med. Genet. B 165, 283-293 (2014)
Hirsch, O., Strauch, K., Held, H., Redaelli, M., Chenot, J.F., Leonhardt, C., Keller, S., Baum, E., Pfingsten,
M., Hildebrandt, J., Basler, H.D., Kochen, M.M., Donner-Banzhoff, N., Becker, A.°: Low back pain patient
subgroups in primary care - pain characteristics, psychosocial determinants and health care utilization. Clin.
J. Pain 30, 1023-1032 (2014)
Hoggart, C.J., Venturini, G., Mangino, M., Gomez, F., Ascari, G., Zhao, J.H., Teumer, A., Winkler, T.W.,
Tsernikova, N., Luan, J., Mihailov, E., Ehret, G.B., Zhang, W., Lamparter, D., Esko, T., Mace, A., Rüeger, S.,
Bochud, P.Y., Barcella, M., Dauvilliers, Y., Benyamin, B., Evans, D.M., Hayward, C., Lopez, M.F., Franke, L.,
Russo, A., Heid, I.M., Salvi, E., Vendantam, S., Arking, D.E., Boerwinkle, E., Chambers, J.C., Fiorito, G.,
Grallert, H., Guarrera, S., Homuth, G., Huffman, J.E., Porteous, D.J., Generation Scotland Consortium
(Loos, R.J.), LifeLines Cohort Study (Rivolta, C.), GIANT Consortium (Albrecht, E., Gieger, C., Heid, I.M.,
Illig, T., Kutalik, Z.°, Müller-Nurasyid, M., Thorand, B., Wichmann, H.-E.), Moradpour, D., Iranzo, A.,
Hebebrand, J., Kemp, J.P., Lammers, G.J., Aubert, V., Heim, M.H., Martin, N.G., Montgomery, G.W.,
Peraita-Adrados, R., Santamaría, J., Negro, F., Schmidt, C.O., Scott, R.A., Spector, T.D., Strauch, K.,
Völzke, H., Wareham, N.J., Yuan, W., Bell, J.T., Chakravarti, A., Kooner, J.S., Peters, A., Matullo, G.,
Wallaschofski, H., Whitfield, J.B., Paccaud, F., Vollenweider, P., Bergmann, S., Beckmann, J.S., Tafti, M.,
Hastie, N.D., Cusi, D., Bochud, M., Frayling, T.M., Metspalu, A., Jarvelin, M.R., Scherag, A., Smith, G.D.,
Borecki, I.B., Rousson, V., Hirschhorn, J.N.: Novel approach identifies SNPs in SLC2A10 and KCNK9 with
evidence for parent-of-origin effect on Body Mass Index. PLoS Genet. 10:e1004508 (2014)
page 139 of 247
2015-11-23
#
joint first authors
Laschkolnig, A., Kollerits, B., Lamina, C., Meisinger, C., Rantner, B., Stadler, M., Peters, A., Koenig, W.,
Stöckl, A., Dähnhardt, D., Böger, C.A., Krämer, B.K., Fraedrich, G., Strauch, K., Kronenberg, F.°:
Lipoprotein (a) concentrations, apolipoprotein (a) phenotypes, and peripheral arterial disease in three
independent cohorts. Cardiovasc. Res. 103, 28-36 (2014)
Lemaitre, R.N.°, Johnson, C.O., Hesselson, S., Sotoodhenia, N., McKnight, B., Sitlani, C.M., Rea, T.D., King,
I.B., Kwok, P., Mak, A., Li, G., Brody, J., Larson, E., Mozaffarian, D., Psaty, B.M., Huertas-Vazquez, A.,
Tardif, J.C., Albert, C.M., Lyytikaeinen, L., Arking, D.E., Kääb, S., Huikuri, H.V., Krijthe, B.P., Eijgelsheim, M.,
Wang, Y.A., Reinier, K., Lehtimaeki, T., Pulit, S.L., Brugada, R., Müller-Nurasyid, M., Newton-Cheh, C.H.,
Karhunen, P.J., Stricker, B.H., Goyette, P., Rotter, J.I., Chugh, S.S., Chakravarti, A., Jouven, X., Siscovick,
D.S.: Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest. Heart
Rhythm 11, 471-477 (2014)
page 140 of 247
2015-11-23
#
joint first authors
Lieb, W., Chen, M.H., Teumer, A., de Boer, R.A., Lin, H., Fox, E.R., Musani, S.K., Wilson, J.G., Wang, T.J.,
Völzke, H., Petersen, A.K., Meisinger, C., Nauck, M., Schlesinger, S., Li, Y., Ménard, J., Hercberg, S.,
Wichmann, H.-E., Völker, U., Rawal, R., Bidlingmaier, M., Hannemann, A., Dörr, M., Rettig, R., van Gilst,
W.H., van Veldhuisen, D.J., Bakker, S.J., Navis, G., Wallaschofski, H., Meneton, P., van der Harst, P.,
Reincke, M., Vasan, R.S.°, CKDGen Consortium, ICBP Consortium, EchoGen Consortium: Genome-wide
meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and
prekallikrein genes. Circ. Cardiovasc. Genet. 8, 131-140 (2015) [published online 2014]
page 141 of 247
2015-11-23
#
joint first authors
#
#
#
#
#
#
#
#
#
Genet. 46, 669-677 (2014)
Lubitz, S.A.°, Lunetta, K.L., Lin, H., Arking, D.E., Trompet, S., Li, G., Krijthe, B.P., Chasman, D.I., Barnard,
J., Kleber, M.E., Dörr, M., Ozaki, K., Smith, A.V., Müller-Nurasyid, M., Walter, S., Agarwal, S.K., Bis, J.C.,
Brody, J.A., Chen, L.Y., Everett, B.M., Ford, I., Franco, O.H., Harris, T.B., Hofman, A., Kääb, S., Mahida, S.,
Kathiresan, S., Kubo, M., Launer, L.J., Macfarlane, P.W., Magnani, J.W., McKnight, B., McManus, D.D.,
Peters, A., Psaty, B.M., Rose, L.M., Rotter, J.I., Silbernagel, G., Smith, J.D., Sotoodehnia, N., Stott, D.J.,
Taylor, K.D., Tomaschitz, A., Tsunoda, T., Uitterlinden, A.G., van Wagoner, D.R., Völker, U., Völzke, H.,
Murabito, J.M., Sinner, M.F., Gudnason, V., Felix, S.B., Marz, W., Chung, M., Albert, C.M., Stricker, B.H.,
Tanaka, T., Heckbert, S.R., Jukema, J.W., Alonso, A., Benjamin, E.J., Ellinor, P.T.: Novel genetic markers
associate with atrial fibrillation risk in Europeans and Japanese. J. Am. Coll. Cardiol. 63, 1200-1210 (2014)
Lüneburg, N.°, Lieb, W., Zeller, T., Chen, M.H., Maas, R., Carter, A.M., Xanthakis, V., Glazer, N.L.,
Schwedhelm, E., Seshadri, S., Ikram, M.A., Longstreth, W.T. J.r., Fornage, M., König, I.R., Loley, C., Ojeda,
F.M., Schillert, A., Wang, T.J., Sticht, H., Kittel, A., König, J., Benjamin, E.J., Sullivan, L.M., Bernges, I.,
Anderssohn, M., Ziegler, A., Gieger, C., Illig, T., Meisinger, C., Wichmann, H.-E., Wild, P.S., Schunkert, H.,
Psaty, B.M., Wiggins, K.L., Heckbert, S.R., Smith, N., Lackner, K.J., Lunetta, K.L., Blankenberg, S.,
Erdmann, J., Münzel, T., Grant, P.J., Vasan, R.S., Böger, R.H.: Genome-wide association study of L-arginine
and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine. Circ. Cardiovasc.
Genet. 7, 864-872 (2014)
page 142 of 247
2015-11-23
#
joint first authors
Natl. Acad. Sci. U.S.A. 111, 13127-13132 (2014)
Medici, M.#°, Porcu, E.#, Pistis, G.#, Teumer, A., Brown, S.J., Jensen, R.A., Rawal, R., Roef, G.L., Plantinga,
Nassab, M.H., Rhein, M., Heese, P., Glahn, A., Frieling, H., Linnebank, M., Bleich, S., Kornhuber, J.,
Heberlein, A., Grallert, H., Peters, A., Rawal, R., Strauch, K., Hillemacher, T.: No association between the
ALDH2 promoter polymorphism rs886205, alcohol dependence, and risky alcohol consumption in a German
population. Psychiatr. Genet. 25, 41-42 (2015) [published online 2014]
page 143 of 247
2015-11-23
#
joint first authors
#
#
Ng, M.C.Y. , Shriner, D. , Chen, B.H., Li, J., Chen, W., Guo, X., Liu, J., Bielinski, S.J., Yanek, L.R., Nalls,
M.A., Comeau, M.E., Rasmussen-Torvik, L.J., Jensen, R.A., Evans, D.S., Sun, Y.V., An, P., Patel, S.R., Lu,
Y., Long, J., Armstrong, L.L., Wagenknecht, L., Yang, L., Snively, B.M., Palmer, N.D., Mudgal, P., Langefeld,
C.D., Keene, K.L., Freedman, B.I., Mychaleckyj, J.C., Nayak, U., Raffel, L.J., Goodarzi, M.O., Chen, Y.I.,
Taylor, H.A., Correa, A., Sims, M., Couper, D., Pankow, J.S., Boerwinkle, E., Adeyemo, A., Doumatey, A.,
Chen, G., Mathias, R.A., Vaidya, D., Singleton, A.B., Zonderman, A.B., Igo, R.P., Sedor, J.R., FIND
Consortium, Kabagambe, E.K., Siscovick, D.S., McKnight, B., Rice, K., Liu, Y., Hsueh, W.C., Zhao, W.,
Bielak, L.F., Kraja, A., Province, M.A., Bottinger, E.P., Gottesman, O., Cai, Q., Zheng, W., Blot, W.J., Lowe,
W.L., Pacheco, J.A., Crawford, D.C., eMERGE Consortium, DIAGRAM Consortium (Gieger, C., Grallert, H.,
Illig, T., Klopp, N., Müller-Nurasyid, M., Peters, A.), Grundberg, E., MuTHER Consortium, Rich, S.S.,
Hayes, M.G., Shu, X., Loos, R.J.F., Borecki, I.B., Peyser, P.A., Cummings, S.R., Psaty, B.M., Fornage, M.,
Iyengar, S.K., Evans, M.K., Becker, D.M., Kao, W.H.L., Wilson, J.G., Rotter, J.I., Sale, M.M., Liu, S.°, Rotimi,
C.N.°, Bowden, D.W.°, MEDIA Consortium: Meta-analysis of genome-wide association studies in African
Americans provides insights into the genetic architecture of type 2 diabetes. PLoS Genet. 10:e100451
(2014)
Pechlaner, R., Willeit, P., Summerer, M., Santer, P., Egger, G., Kronenberg, F., Demetz, E., Weiss, G.,
Tsimikas, S., Witztum, J.L., Willeit, K., Iglseder, B., Paulweber, B., Kedenko, L., Haun, M., Meisinger, C.,
Gieger, C., Müller-Nurasyid, M., Peters, A., Willeit, J., Kiechl, S.°: Heme oxygenase-1 gene promoter
microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular
disease. Arterioscler. Thromb. Vasc. Biol. 35, 229-236 (2015) [published online 2014]
#
#
Perry, J.R. °, Hsu, Y.H. , Chasman, D.I., Johnson, A.D., Elks, C.E., Albrecht, E., Andrulis, I.L., Beesley, J.,
Berenson, G.S., Bergmann, S., Bojesen, S.E., Bolla, M.K., Brown, J., Buring, J.E., Campbell, H.,
Chang-Claude, J., Chenevix-Trench, G., Corre, T., Couch, F.J., Cox, A., Czene, K., d'Adamo, A.P., Davies,
G., Deary, I.J., Dennis, J., Easton, D.F., Engelhardt, E.G., Eriksson, J.G., Esko, T., Fasching, P.A., Figueroa,
J.D., Flyger, H., Fraser, A., Garcia-Closas, M., Gasparini, P., Gieger, C., Giles, G.G., Guénel, P., Hägg, S.,
Hall, P., Hayward, C., Hopper, J.L., Ingelsson, E., kConFab Investigators, Kardia, S.L., Kasiman, K., Knight,
J.A., Lahti, J., Lawlor, D.A., Magnusson, P.K., Margolin, S., Marsh, J.A., Metspalu, A., Olson, J.E., Pennell,
C.E., Polasek, O., Rahman, I., Ridker, P.M., Robino, A., Rudan, I., Rudolph, A., Salumets, A., Schmidt, M.K.,
Schoemaker, M.J., Smith, E.N., Smith, J.A., Southey, M., Stöckl, D., Swerdlow, A.J., Thompson, D.J.,
Truong, T., Ulivi, S., Waldenberger, M., Wang, Q., Wild, S., Wilson, J.F., Wright, A.F., Zgaga, L., RepoGen
Consortium, Ong, K.K., Murabito, J.M., Karasik, D., Murray, A.°: DNA mismatch repair gene MSH6
implicated in determining age at natural menopause. Hum. Mol. Genet. 23, 2490-2497 (2014)
page 144 of 247
2015-11-23
#
joint first authors
#
#
#
#
Perry, J.R.B. °, Day, F. , Elks, C.E. , Sulem, P. , Thompson, D.J., Ferreira, T., He, C., Chasman, D.I., Esko,
T., Thorleifsson, G., Albrecht, E., Ang, W.Q., Corre, T., Cousminer, D.L., Feenstra, B., Franceschini, N.,
Ganna, A., Johnson, A.D., Kjellqvist, S., Lunetta, K.L., McMahon, G., Nolte, I.M., Paternoster, L., Porcu, E.,
Smith, A.V., Stolk, L., Teumer, A., Tsernikova, N., Tikkanen, E., Ulivi, S., Wagner, E.K., Amin, N., Bierut,
L.J., Byrne, E.M., Hottenga, J.-J., Koller, D.L., Mangino, M., Pers, T.H., Yerges-Armstrong, L.M, Zhao, J.H.,
Andrulis, I.L., Anton-Culver, H., Atsma, F., Bandinelli, S., Beckmann, M.W., Benítez, J., Blomqvist, C.,
Bojesen, S.E., Bolla, M.K., Bonanni, B., Brauch, H., Brenner, H., Buring, J.E., Chang-Claude, J., Chanock,
S., Chen, J., Chenevix-Trench, G., Collee, J.M., Couch, F.J., Couper, D., Coviello, A.D., Cox, A., Czene, K.,
D’adamo, A.P., Smith, G.D., de Vivo, I., Demerath, E.W., Dennis, J., Devilee, P., Dieffenbach, A.K., Dunning,
A.M., Eiriksdottir, G., Eriksson, J.G., Fasching, P.A., Ferrucci, L., Flesch-Janys, D., Flyger, H., Foroud, T.,
Franke, L., Garcia, M.E., Garcia-Closas, M., Geller, F., de Geus, E.J., Giles, G.G., Gudbjartsson, D.F.,
Gudnason, V., Guénel, P., Guo, S., Hall, P., Hamann, U., Haring, R., Hartman, C.A., Heath, A.C., Hofman,
A., Hooning, M.J., Hopper, J.L., Hu, F.B., Hunter, D.J., Karasik, D., Kiel, D.P., Knight, J.A., Kosma, V.M.,
Kutalik, Z., Lai, S., Lambrechts, D., Lindblom, A., Mägi, R., Magnusson, P.K., Mannermaa, A., Martin, N.G.,
Masson, G., McArdle, P.F., McArdle, W.L., Melbye, M., Michailidou, K., Mihailov, E., Milani, L., Milne, R.L.,
Nevanlinna, H., Neven, P., Nohr, E.A., Oldehinkel, A.J., Oostra, B.A., Palotie, A., Peacock, M., Pedersen,
N.L., Peterlongo, P., Peto, J., Pharoah, P.D.P., Postma, D.S., Pouta, A., Pylkäs, K., Radice, P., Ring, S.,
Rivadeneira, F., Robino, A., Rose, L.M., Rudolph, A., Salomaa, V., Sanna, S., Schlessinger, D., Schmidt,
M.K., Southey, M.C., Sovio, U., Stampfer, M., Stöckl, D., Storniolo, A., Timpson, N.J., Tyrer, J., Visser, J.A.,
Vollenweider, P., Völzke, H., Waeber, G., Waldenberger, M., Wallaschofski, H., Wang, Q., Willemsen, G.,
Winqvist, R., Wolffenbuttel, B.H.R., Wright, M.J., Boomsma, D.I., Econs, M.J., Khaw, K.-T., Loos, R.J.F.,
McCarthy, M.I., Montgomery, G.W., Rice, J.P., Streeten, E.A., Thorsteinsdottir, U., van Duijn, C.M., Alizadeh,
B.Z., Bergmann, S., Boerwinkle, E., Boyd, H.A., Crisponi, L., Gasparini, P., Gieger, C., Harris, T.B.,
Ingelsson, E., Järvelin, M.-R., Kraft, P., Lawlor, D., Metspalu, A., Pennell, C.E., Ridker, P.M., Snieder, H.,
Sørensen, T.I., Spector, T.D., Strachan, D.P., Uitterlinden, A.G., Wareham, N.J., Widen, E., Zygmunt, M.,
Murray, A., Easton, D.F., Stefansson, K., Murabito, J.M.°, Ong, K.K.: Parent-of-origin specific allelic
associations among 106 genomic1 loci for age at menarche. Nature 514, 92-97 (2014)
Reinthaler, E.M.#, Lal, D.#, Lebon, S., Hildebrand, M.S., Dahl, H.H., Regan, B.M., Feucht, M., Steinböck, H.,
Neophytou, B., Ronen, G.M., Roche, L., Gruber-Sedlmayr, U., Geldner, J., Haberlandt, E., Hoffmann, P.,
Herms, S., Gieger, C., Waldenberger, M., Franke, A., Wittig, M., Schoch, S., Becker, A.J., Hahn, A.,
Männik, K., Toliat, M.R., Winterer, G., Lerche, H., Nürnberg, P., Mefford, H.C., Scheffer, I.E., Berkovic, S.F.,
Beckmann, J.S., EPICURE Consortium (Reymond, A.), EuroEPINOMICS Consortium (Zimprich, F.°),
Sander, T., Jacquemont, S., Neubauer, B.A.: 16p11.2 600 kb duplications confer risk for typical and atypical
Rolandic epilepsy. Hum. Mol. Genet. 23, 6069-6080 (2014)
page 145 of 247
2015-11-23
#
joint first authors
#
#
Schäfer, A.S.°, Bochenek, G., Jochens, A., Ellinghaus, D., Dommisch, H., Guzeldemir-Akcakana, E., Graetz,
C., Harks, I., Jockel-Schneider, Y., Weinspach, K., Meyle, J., Eickholz, P., Linden, G.J., Cine, N., Nohutcu,
R., Weiss, E., Houri-Haddad, Y., Iraqi, F., Folwaczny, M., Noack, B., Strauch, K., Gieger, C.,
Waldenberger, M., Peters, A., Wijmenga, C., Yilmaz, E., Lieb, W., Rosenstiel, P., Doerfer, C., Bruckmann,
C., Erdmann, J., König, I., Jepsen, S., Loos, B.G., Schreiber, S.: Genetic evidence for PLASMINOGEN as a
shared genetic risk factor of coronary artery disease and periodontitis. Circ. Cardiovasc. Genet. 8, 159-167
Schulte, E.C.#, Kousi, M.#, Tan, P.L., Tilch, E., Knauf, F., Lichtner, P., Trenkwalder, C., Högl, B.,
#
#
(2014)
page 146 of 247
2015-11-23
#
joint first authors
#
#
#
#
Shin, S.Y. , Fauman, E.B. , Petersen, A.-K. , Krumsiek, J. , Santos, R., Huang, J., Arnold, M., Erte, I.,
Nat. Genet. 46, 543-550 (2014)
Simino, J.°, Shi, G., Bis, J.C., Chasman, D.I., Ehret, G., Gu, X., Guo, X., Hwang, S.J., Sijbrands, E.J.G.,
Smith, A.C.M., Verwoert, G., Bragg-Gresham, J.L., Cadby, G., Chen, P., Cheng, C., Corre, T., de Boer, R.,
Goel, A.K., Johnson, T., Khor, C.C., Lluís-Ganella, C., Luan, J., Lyytikäinen, L.P., Nolte, I.M., Sim, X., Sõber,
S., van der Most, P.J., Verweij, N., Zhao, J., Amin, N., Boerwinkle, E.E., Bouchard, C., Dehghan, A.,
Eiriksdottir, G., Elosua, R., Franco, O.H., Gieger, C., Harris, T.B., Hercberg, S., Hofman, A.F., James, A.L.,
Johnson, A.D., Kähönen, M., Khaw, K.T., Kutalik, Z., Larson, M.G., Launer, L.J., Li, G., Liu, J., Liu, K.,
Morrison, A.C., Navis, G.J., Ong, R.T.H., Papanicolau, G.J., Penninx, B.W.J.H., Psaty, B.M., Raffel, L.J.,
Raitakari, O.T., Rice, K., Rivadeneira, F.F., Rose, L.M., Sanna, S., Scott, R.A., Siscovick, D.S., Stolk, R.P.,
Uitterlinden, A.G., Vaidya, D., van der Klauw, M.M., Vasan, R.S., Vithana, E.N., Völker, U., Völzke, H.,
Watkins, H.C., Young, T.L., Aung, T., Bochud, M., Farrall, M., Hartman, C.A., Laan, M., Lakatta, E.G.,
Lehtimäki, T., Loos, R.J.F., Lucas, G., Meneton, P., Palmer, L.J., Rettig, R., Snieder, H., Tai, E.S., Teo, Y.Y.,
van der Harst, P., Wareham, N.J., Wijmenga, C., Wong, T.Y., Fornage, M., Gudnason, V.G., Levy, D.,
Palmas, W.R., Ridker, P.M., Rotter, J.I., van Duijn, C.M., Witteman, J.C.M., Chakravarti, A.°, Rao, D.C.:
Gene-age interactions in blood pressure regulation: A large-scale investigation with the CHARGE, Global
BPgen, and ICBP consortia. Am. J. Hum. Genet. 95, 24-38 (2014)
ONE 9:e107110 (2014)
Sinner, M.F.#, Tucker, N.R.#, Lunetta, K.L.#, Ozaki, K.#, Smith, J.G.#, Trompet, S.#, Bis, J.C.#, Lin, H.#, Chung,
M.K.#, Nielsen, J.B.#, Lubitz, S.A.#, Krijthe, B.P.#, Magnani, J.W.#, Ye, J., Gollob, M.H., Tsunoda, T.,
Müller-Nurasyid, M., Lichtner, P., Peters, A., Dolmatova, E., Kubo, M., Smith, J.D., Psaty, B.M., Smith,
N.L., Jukema, J.W., Chasman, D.I., Albert, C.M., Ebana, Y., Furukawa, T., Macfarlane, P.W., Harris, T.B.,
Darbar, D., Dörr, M., Holst, A.G., Svendsen, J.H., Hofman, A., Uitterlinden, A., Gudnason, V., Isobe, M.,
Malik, R., Dichgans, M., Rosand, J., van Wagoner, D.R., METASTROKE Consortium (Kääb, S.), AFGen
Consortium (Ellinor, P.T.°), Benjamin, E.J., Milan, D.J., Melander, O., Heckbert, S.R, Ford, I., Liu, Y.,
Barnard, J., Olesen, M.S., Stricker, B.H., Tanaka, T.: Integrating genetic, transcriptional, and functional
analyses to identify five novel genes for atrial fibrillation. Circulation 130, 1225-1235 (2014)
page 147 of 247
2015-11-23
#
joint first authors
Slater, E.P.°, Strauch, K., Rospleszcz, S., Ramaswamy, A., Esposito, I., Klöppel, G., Mätthai, E., Heeger,
K., Fendrich, V., Langer, P., Bartsch, D.K.: MicroRNA-196a and -196b as potential biomarkers for the early
detection of familial pancreatic cancer. Transl. Oncol. 7, 464-471 (2014)
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Spyroglou, A. , Bozoglu, T. , Rawal, R., de Leonardis, F., Sterner, C., Boulkroun, S., Benecke, A.G., Monti,
L., Zennaro, M.C., Petersen, A.-K., Döring, A., Rossi, A., Bidlingmaier, M., Warth, R., Gieger, C., Reincke,
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M. , Beuschlein, F. °: Diastrophic dysplasia sulfate transporter (SLC26A2) is expressed in the adrenal cortex
and regulates aldosterone secretion. Hypertension 63, 1102-1109 (2014)
Sundqvist, E., Buck, D., Warnke, C., Albrecht, E., Gieger, C., Khademi, M., Lima Bomfim, I., Fogdell-Hahn,
A., Link, J., Alfredsson, L., Søndergaard, H.B., Hillert, J., Oturai, A.B., Hemme, B., Kockum, I.°, Olsson, T.:
JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants. PLoS Pathog.
10:e1004084 (2014)
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Tang, W. , Kowgier, M. , Loth, D.W. , Soler Artigas, M. , Joubert, B.R. , Hodge, E. , Gharib, S.A. , Smith,
A.V., Ruczinski, I., Gudnason, V., Mathias, R.A., Harris, T.B., Hansel, N.N., Launer, L.J., Barnes, K.C.,
Hansen, J.G., Albrecht, E., Aldrich, M.C., Allerhand, M., Barr, R.G., Brusselle, G.G., Couper, D.J., Curjuric,
I., Davies, G., Deary, I.J., Dupuis, J., Fall, T., Foy, M., Franceschini, N., Gao, W., Gläser, S., Gu, X.,
Hancock, D.B., Heinrich, J., Hofman, A., Imboden, M., Ingelsson, E., James, A., Karrasch, S., Koch, B.,
Kritchevsky, S.B., Kumar, A., Lahousse, L., Li, G., Lind, L., Lindgren, C., Liu, Y., Lohman, K., Lumley, T.,
McArdle, W.L., Meibohm, B., Morris, A.P., Morrison, A.C., Musk, B., North, K.E., Palmer, L.J.,
Probst-Hensch, N.M., Psaty, B.M., Rivadeneira, F., Rotter, J.I., Schulz, S., Smith, L.J., Sood, A., Starr, J.M.,
Strachan, D.P., Teumer, A., Uitterlinden, A.G., Völzke, H., Voorman, A., Wain, L.V., Wells, M.T., Wilk, J.B.,
Williams, O.D., Heckbert, S.R., Stricker, B.H., London, S.J., Fornage, M., Tobin, M.D., O'Connor, G.T., Hall,
I.P., Cassano, P.A.°: Large-scale genome-wide association studies and meta-analyses of longitudinal
change in adult lung function. PLoS ONE 9:e100776 (2014)
page 148 of 247
2015-11-23
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joint first authors
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Tragante, V. , Barnes, M.R. , Ganesh, S.K. , Lanktree, M.B., Guo, W., Franceschini, N., Smith, E.N.,
Johnson, T., Holmes, M.V., Padmanabhan, S., Karczewski, K.J., Almoguera, B., Barnard, J., Baumert, J.J.,
Chang, Y.-P., Elbers, C.C., Farrall, M., Fischer, M.E., Gaunt, T.R., Gho, J.M.I.H., Gieger, C., Goel, A., Gong,
Y., Isaacs, A., Kleber, M.E., Leach, I.M., McDonough, C.W., Meijs, M.F.L., Melander, O., Nelson, C.P., Nolte,
I.M., Pankratz, N., Price, T.S., Shaffer, J., Shah, S., Tomaszewski, M., van der Most, P.J., Van Iperen,
E.P.A., Vonk, J.M., Witkowska, K., Wong, C.O.L., Zhang, L., Beitelshees, A.L., Berenson, G.S., Bhatt, D.L.,
Brown, M., Burt, A., Cooper-DeHoff, R.M., Connell, J.M., Cruickshanks, K.J., Curtis, S.P., Davey-Smith, G.,
Delles, C., Gansevoort, R.T., Guo, X., Haiqing, S., Hastie, C.E., Hofker, M.H., Hovingh, G.K., Kim, D.S.,
Kirkland, S.A., Klein, B.E., Klein, R., Li, Y.R., Maiwald, S., Newton-Cheh, C., O'Brien, E.T., Onland-Moret,
N. ., Palmas, W., Parsa, A., Penninx, B.W., Pettinger, M., Vasan, R.S., Ranchalis, J.E., Ridker, P.M., Rose,
L.M., Sever, P., Shimbo, D., Steele, L., Stolk, R.P., Thorand, B., Trip, M.D., van Duijn, C.M., Verschuren,
W.M., Wijmenga, C., Wyatt, S., Young, J., Zwinderman, A.H., Bezzina, C.R., Boerwinkle, E., Casas, J.P.,
Caulfield, M.J., Chakravarti, A., Chasman, D.I., Davidson, K.W., Doevendans, P.A., Dominiczak, A.F.,
Fitzgerald, G.A., Gums, J.G., Fornage, M., Hakonarson, H., Halder, I., Hillege, H.L., Illig, T., Jarvik, G.P.,
Johnson, J.A., Kastelein, J.J.P., Koenig, W., Kumari, M., Marz, W., Murray, S.S., O'Connell, J.R., Oldehinkel,
A.J., Pankow, J.S., Rader, D.J., Redline, S., Reilly, M.P., Schadt, E.E., Kottke-Marchant, K., Snieder, H.,
Snyder, M., Stanton, A.V., Tobin, M.D., Uitterlinden, A.G., van der Harst, P., van der Schouw, Y.T., Samani,
N.J., Watkins, H., Johnson, A.D., Reiner, A.P., Zhu, X., de Bakker, P.I.W., Levy, D., Asselbergs, F.W.,
Munroe, P.B.°, Keating, B.J.°: Gene-centric meta-analysis in 87,736 individuals of European ancestry
identifies multiple blood-pressure-related loci. Am. J. Hum. Genet. 94, 349-360 (2014)
Tsepilov, Y.A., Ried, J.S., Strauch, K., Grallert, H., van Duijn, C.M., Axenovich, T.I., Aulchenko, Y.S.°:
Development and application of genomic control methods for genome-wide association studies using
non-additive models. PLoS ONE 8:e81431 (2013)
Viniol, A.°, Jegan, N., Hirsch, O., Leonhardt, C., Brugger, M., Strauch, K., Barth, J.A.C., Baum, E., Becker,
A.: Chronic low back pain patient groups in primary care - a cross sectional cluster analysis. BMC
Musculoskelet. Disord. 14:294 (2013)
Viniol, A.°, Jegan, N., Leonhardt, C., Brugger, M., Strauch, K., Barth, J., Baum, E., Becker, A.: Differences
between patients with chronic widespread pain and local chronic low back pain in primary care - a
comparative cross-sectional analysis. BMC Musculoskelet. Disord. 14:351 (2013)
15:232 (2014)
page 149 of 247
2015-11-23
#
joint first authors
Walsh, K.M.°, Codd, V., Smirnov, I.V., Rice, T., Decker, P.A., Hansen, H.M., Kollmeyer, T., Kosel, M.L.,
Molinaro, A.M., McCoy, L.S., Bracci, P.M., Cabriga, B.S., Pekmezci, M., Zheng, S., Wiemels, J.L., Pico, A.R.,
Tihan, T., Berger, M.S., Chang, S.M., Prados, M.D., Lachance, D.H., O'Neill, B.P., Sicotte, H.,
Eckel-Passow, J.E., ENGAGE Consortium Telomere Group (Albrecht, E., Klopp, N., Peters, A.,
Wichmann, H.-E., Gieger, C.), van der Harst, P., Wiencke, J.K., Samani, N.J., Jenkins, R.B., Wrensch,
M.R.: Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.
Nat. Genet. 46, 731-735 (2014)
Am. J. Hum. Genet. 94, 710-720 (2014)
Winkler, T.W., Day, F.R., Croteau-Chonka, D.C., Wood, A.R., Locke, A.E., Mägi, R., Ferreira, T., Fall, T.,
Graff, M., Justice, A.E., Luan, J., Gustafsson, S., Randall, J.C., Vedantam, S., Workalemahu, T., Kilpeläinen,
T.O., Scherag, A., Esko, T., Kutalik, Z., Heid, I.M.°, Loos, R.J.°, GIANT Consortium (Albrecht, E.,
Müller-Nurasyid, M., Grallert, H., Peters, A., Thorand, B., Gieger, C., Illig, T., Wichmann, H.-E.): Quality
control and conduct of genome-wide association meta-analyses. Nat. Protoc. 9, 1192-1212 (2014)
page 150 of 247
2015-11-23
#
joint first authors
page 151 of 247
2015-11-23
#
joint first authors
height. Nat. Genet. 46, 1173-1186 (2014)
Work, M.E., Reimers, L.L., Quante, A.S., Crew, K.D., Whiffen, A., Terry, M.B.°: Changes in mammographic
density over time in breast cancer cases and women at high risk for breast cancer. Int. J. Cancer 135,
1740-1744 (2014)
Xi, B., Takeuchi, F., Meirhaeghe, A., Kato, N., Chambers, J.C., Morris, A.P., Cho, Y.S., Zhang, W., Mohlke,
K.L., Kooner, J.S., Shu, X.O., Pan, H., Tai, E.S., Pan, H., Wu, J., Zhou, D.°, Chandak, G.R., DIAGRAM
Consortium (Gieger, C., Grallert, H., Illig, T., Klopp, N., Müller-Nurasyid, M., Peters, A.), AGEN-T2D
Consortium, SAT2D Consortium: Associations of genetic variants in/near body mass index-associated genes
with type 2 diabetes: A systematic meta-analysis. Clin. Endocrinol. 81, 702-710 (2014)
Yoneyama, S.#, Guo, Y.#, Lanktree, M.B.#, Barnes, M.R.#, Elbers, C.C., Karczewski, K.J., Padmanabhan, S.,
2498-2510 (2014)
page 152 of 247
2015-11-23
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joint first authors
Zech, M.#, Castrop, F.#, Schormair, B., Jochim, A., Wieland, T., Gross, N., Lichtner, P., Peters, A.,
(2014)
page 153 of 247
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Institute of Groundwater Ecology
®
Ballarini, E.°, Beyer, C., Bauer, R.D., Griebler, C., Bauer, S.°: Model based evaluation of a contaminant
plume development under aerobic and anaerobic conditions in 2D bench-scale tank experiments.
Biodegradation 25, 351-371 (2013)
Bosch, J.°, Lee, K.Y., Hong, S.F., Harnisch, F., Schröder, U., Meckenstock, R.U.: Metabolic efficiency of
Geobacter sulfurreducens growing on anodes with different redox potentials. Curr. Microbiol. 68, 763-768
(2014)
Braunschweig, J., Klier, C., Schröder, C., Händel, M., Bosch, J., Totsche, K.U., Meckenstock, R.U.°:
Citrate influences microbial Fe hydroxide reduction via a dissolution-disaggregation mechanism. Geochim.
Cosmochim. Acta 139, 434-446 (2014)
Cretnik, S., Bernstein, A., Shouakar-Stash, O., Löffler, F.E., Elsner, M.°: Chlorine isotope effects from
isotope ratio mass spectrometry suggest intramolecular C-Cl bond competition in Trichloroethene (TCE)
reductive dehalogenation. Molecules 19, 6450-6473 (2014)
Deng, L.#, Krauss, S.#, Feichtmayer, J., Hofmann, R., Arndt, H., Griebler, C.°: Grazing of heterotrophic
flagellates on viruses is driven by feeding behaviour. Environ. Microbiol. Rep. 6, 325-330 (2014)
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Deng, L. °, Ignacio-Espinoza, J.C. , Gregory, A.C., Poulos, B.T., Weitz, J.S., Hugenholtz, P., Sullivan, M.B.:
Viral tagging reveals discrete populations in Synechococcus viral genome sequence space. Nature 513,
242-245 (2014)
Dibbern, D., Schmalwasser, A., Lüders, T.°, Totsche, K.U.: Selective transport of plant root-associated
bacterial populations in agricultural soils upon snowmelt. Soil Biol. Biochem. 69, 187-196 (2014)
Frank-Fahle, B., Yergeau, E., Greer, C.W., Lantuit, H., Wagner, D.°: Microbial functional potential and
community composition in permafrost-affected soils of the NW Canadian Arctic. PLoS ONE 9:e84761 (2014)
Griebler, C.°, Malard, F., Lefebure, T.: Current developments in groundwater ecology - from biodiversity to
ecosystem function and services. Curr. Opin. Biotechnol. 27, 159-167 (2014)
Herzyk, A., Maloszewski, P., Qiu, S., Elsner, M., Griebler, C.°: Intrinsic potential for immediate
biodegradation of toluene in a pristine, energy-limited aquifer. Biodegradation 25, 325-336 (2014)
Hose, G.C.°, Bailey, J., Stumpp, C., Fryirs, K.: Groundwater depth and topography correlate with vegetation
structure of an upland peat swamp, Budderoo Plateau, NSW, Australia. Ecohydrology 7, 1392-1402 (2014)
Kármán, K.°, Maloszewski, P., Deák, J., Fórizs, I., Szabo, C.: Transit time determination for a riverbank
filtration system using oxygen isotope data and the lumped-parameter model. Hydrol. Sci. J. 59, 1109-1116
(2014)
page 154 of 247
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joint first authors
Karwautz, C., Lueders, T.°: Impact of hydraulic well restoration on native bacterial communities in drinking
water wells. Microbes Environ. 29, 363-369 (2014)
Klaus, J.°, Zehe, E., Elsner, M., Palm, J., Schneider, D., Schröder, B., Steinbeiss, S., van Schaik, L., West,
S.: Controls of event-based pesticide leaching in natural soils: A systematic study based on replicated field
scale irrigation experiments. J. Hydrol. 512, 528-539 (2014)
Kleindienst, S., Herbst, F.A., Stagars, M., von Netzer, F., von Bergen, M., Seifert, J., Peplies, J., Amann, R.,
Musat, F., Lueders, T., Knittel, K.°: Diverse sulfate-reducing bacteria of the Desulfosarcina/Desulfococcus
clade are the key alkane degraders at marine seeps. ISME J. 8, 2029-2044 (2014)
Koenig, J.C.°, Groissmeier, K.D., Manefield, M.J.: Tolerance of anaerobic bacteria to chlorinated solvents.
Microbes Environ. 29, 23-30 (2014)
Kübeck, C.°, Maloszewski, P., Benischke, R.: Modellbasierte Berechnung der AbflussStofftransportprozesse in hierarchisch organisierten Karstnetzwerken. Grundwasser 19, 61-71 (2014)
und
Kuppardt, A.°, Kleinsteuber, S., Vogt, C., Lüders, T., Harms, H., Chatzinotas, A.: Phylogenetic and
functional diversity within toluene-degrading, sulphate-reducing consortia enriched from a contaminated
aquifer. Microb. Ecol. 68, 222-234 (2014)
Madioune, D.H., Faye, S., Orban, P., Brouyère, S., Dassargues, A., Mudry, J., Stumpp, C., Maloszewski,
P.°: Application of isotopic tracers as a tool for understanding hydrodynamic behavior of the highly exploited
Diass aquifer system (Senegal). J. Hydrol. 511, 443-459 (2014)
Magalhães, C.M.°, Machado, A., Frank-Fahle, B., Lee, C.K., Cary, S.C.: The ecological dichotomy of
ammonia-oxidizing archaea and bacteria in the hyper-arid soils of the Antarctic Dry Valleys. Front. Microbiol.
5:515 (2014)
Maier, M., d,e Corte, S., Nitsche, S., Spaett, T., Boon, N., Elsner, M.°: C & N isotope analysis of diclofenac
to distinguish oxidative and reductive transformation and to track commercial products. Environ. Sci.
Technol. 48, 2312-2320 (2014)
Geobacter metallireducens under excess and limitation of electron donors. Part I. Batch cultivation with
excess of carbon sources. Syst. Appl. Microbiol. 37, 277-286 (2014)
Geobacter metallireducens under excess and limitation of electron donors. Part II. Mimicking environmental
conditions during cultivation in retentostats. Syst. Appl. Microbiol. 37, 287-295 (2014)
Meckenstock, R.U.°, von Netzer, F., Stumpp, C., Lueders, T., Himmelberg, A.M., Hertkorn, N.,
Schmitt-Kopplin, P., Harir, M., Hosein, R., Haque, S., Schulze-Makuch, D.: Water droplets in oil are
microhabitats for microbial life. Science 345, 673-676 (2014)
page 155 of 247
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joint first authors
Meyer, A.H., Dybala-Defratyka, A., Alaimo, P.J., Geronimo, I., Sanchez, A.D., Cramer, C.J., Elsner, M.°:
Cytochrome P450-catalyzed dealkylation of atrazine by Rhodococcus sp. strain NI86/21 involves hydrogen
atom transfer rather than single electron transfer. Dalton Trans. 43, 12175-12186 (2014)
Müller, J.°, Hense, B.A., Marozava, S., Kuttler, C., Meckenstock, R.U.: Model selection for microbial
nutrient uptake using a cost-benefit approach. Math. Biosci. 255, 52-70 (2014)
Müller, M.H.°, Alaoui, A., Kuells, C., Leistert, H., Meusburger, K., Stumpp, C., Weiler, M., Alewell, C.:
18
Tracking water pathways in steep hillslopes by δ O depth profiles of soil water. J. Hydrol. 519, 340-352
(2014)
Palau, J.°, Cretnik, S., Shouakar-Stash, O., Höche, M., Elsner, M., Hunkeler, D.: C and Cl isotope
fractionation of 1,2-dichloroethane displays unique δ13C/δ37Cl patterns for pathway identification and reveals
surprising C-Cl bond involvement in microbial oxidation. Environ. Sci. Technol. 48, 9430-9437 (2014)
Pérez-de-Mora, A.°, Zila, A., McMaster, M.L., Edwards, E.A.: Bioremediation of chlorinated ethenes in
fractured bedrock and associated changes in dechlorinating and nondechlorinating microbial populations.
Environ. Sci. Technol. 48, 5770-5779 (2014)
Pérez-de-Mora, A., Laquitaine, L., Gaspard, S.°: Microorganisms for soil treatment. RSC Green Chem.,
144-221 (2014)
Qiu, S., Gözdereliler, E., Weyrauch, P., Lopez, E.C., Kohler, H.P., Sørensen, S.R., Meckenstock, R.U.,
13
12
Elsner, M.°: Small
C/ C fractionation contrasts with large enantiomer fractionation in aerobic
biodegradation of phenoxy acids. Environ. Sci. Technol. 48, 5501-5511 (2014)
Renpenning, J., Keller, S., Cretnik, S., Shouakar-Stash, O., Elsner, M., Schubert, T., Nijenhuis, I.°:
Combined C and Cl isotope effects indicate differences between corrinoids and enzyme (Sulfurospirillum
multivorans PceA) in reductive dehalogenation of tetrachloroethene, but not trichloroethene. Environ. Sci.
Technol. 48, 11837-11845 (2014)
Rühle, F., Zentner, N., Stumpp, C.°: Changes in water table level influence solute transport in uniform
porous media. Hydrol. Process. 29, 875-888 (2015) [published online 2014]
Ssebugere, P., Sillanpää, M., Wang, P., Li, Y., Kiremire, B.T., Kasozi, G.N., Zhu, C., Ren, D., Shang, H.,
Zhang, Q.°, Jiang, G.: Polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and polybrominated
diphenyl ethers in sediments and fish species from the Murchison Bay of Lake Victoria, Uganda. Sci. Total
Environ. 500-501, 1-10 (2014)
Stumpp, C.°, Klaus, J., Stichler, W.: Analysis of long-term stable isotopic composition in German
precipitation. J. Hydrol. 517, 351-361 (2014)
Stumpp, C.°, Ekdal, A., Gönenc, I.E., Maloszewski, P.: Hydrological dynamics of water sources in a
Mediterranean lagoon. Hydrol. Earth Syst. Sci. 18, 4825-4837 (2014)
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Institute of Health Economics and Health Care Management
Al-Khadra, S., Meisinger, C., Amann, U., Holle, R., Kuch, B., Seidl, H., Kirchberger, I.°: Secondary
prevention medication after myocardial infarction: Persistence in elderly people over the course of 1 year.
Drugs Aging 31, 513-525 (2014)
Aljutaili, M., Becker, C., Witt, S., Holle, R., Leidl, R., Block, M., Brachmann, J., Silber, S., Bestehorn, K.,
Stollenwerk, B.°: Should health insurers target prevention of cardiovascular disease? A cost-effectiveness
analysis of an individualised programme in Germany based on routine data. BMC Health Serv. Res. 14:263
(2014)
Bauer, K., Schwarzkopf, L.°, Graessel, E., Holle, R.: A claims data-based comparison of comorbidity in
individuals with and without dementia. BMC Geriatr. 14:10 (2014)
Becker, C.°: Cost-of-illness studies of atrial fibrillation: Methodological considerations. Expert Rev.
Pharmacoecon. Outcomes Res. 14, 661-684 (2014)
Bock, J.O.°, Brettschneider, C., Seidl, H., Bowles, D., Holle, R., Greiner, W., König, H.H.: Ermittlung
standardisierter Bewertungssätze aus gesellschaftlicher Perspektive für die gesundheitsökonomische
Evaluation. Gesundheitswesen 77, 53-61 (2015) [published online 2014]
Eickholz, P., Röllke, L., Schacher, B., Wohlfeil, M., Dannewitz, B., Kaltschmitt, J., Krieger, J.K., Krigar, D.M.,
Reitmeir, P.°, Kim, T.: Enamel matrix derivative in propylene glycol alginate for treatment of infrabony
defects with or without systemic doxycycline: 12- and 24-month results. J. Periodontol. 85, 669-675 (2014)
Fischer, K.E.°, Rogowski, W.H.: Funding decisions for newborn screening: A comparative review of 22
decision processes in Europe. Int. J. Environ. Res. Public Health 11, 5403-5430 (2014)
Grintsova, O., Maier, W., Mielck, A.°: Inequalities in health care among patients with type 2 diabetes by
individual Socio-Economic Status (SES) and regional deprivation: A systematic literature review. Int. J.
Equity Health 13:43 (2014)
Grundmann, N.°, Mielck, A.°, Siegel, M.°, Maier, W.°: Area deprivation and the prevalence of type 2
diabetes and obesity: Analysis at the municipality level in Germany. BMC Public Health 14:1264 (2014)
Hatz, M.H.M.°, Leidl, R., Yates, N.A., Stollenwerk, B.: A systematic review of the quality of economic
models comparing thrombosis inhibitors in patients with acute coronary syndrome undergoing percutaneous
coronary intervention. Pharmacoeconomics 32, 377-393 (2014)
page 157 of 247
2015-11-23
#
joint first authors
Hatz, M.H.M.°, Schremser, K., Rogowski, W.H.°: Is individualized medicine more cost-effective? A
systematic review. Pharmacoeconomics 32, 443-455 (2014)
Hess, W.°, Schwarzkopf, L., Hunger, M., Holle, R.: Competing-risks duration models with correlated
random effects: An application to dementia patients' transition histories. Stat. Med. 33, 3919-3931 (2014)
Hofmann, M., Mielck, A.°: Gesundheitliche Chancengleichheit und Kosten-Effektivität: Was sagen wichtige
gesundheitspolitische Akteure zu diesem potentiellen Zielkonflikt? Gesundheitswesen 77, 81-85 (2015)
Hollederer, A.°, Braun, G.E., Dahlhoff, G., Drexler, H., Engel, J., Gräßel, E., Häusler, E., Heide, H.,
Heuschmann, P.U., Hörl, G., Imhof, H., Kaplan, M., Kasperbauer, R., Klemperer, D., Kolominsky-Rabas, P.,
Kuhn, J., Lang, M., Langejürgen, R., Lankes, A., Leidl, R., Liebl, B., Loss, J., Ludewig, K., Mansmann, U.,
Melcop, N., Nagels, K., Nowak, D., Pfundner, H., Reuschenbach, B., Schneider, A., Schneider, W.,
Schöffski, O., Schreiber, W., Voigtländer, S., Wildner, M., Zapf, A., Zellner, A.: Memorandum
„Weiterentwicklung
der
Gesundheitsversorgungsforschung
in
Bayern
aus
Sicht
der
Landesarbeitsgemeinschaft Gesundheitsversorgungsforschung: Status quo – Entwicklungspotenziale –
Strategien“. Gesundheitswesen 77, 180-185 (2015) [published online 2014]
Hoogendoorn, M.°, Feenstra, T.L., Asukai, Y., Borg, S., Hansen, R.N., Jansson, S.A., Samyshkin, Y.,
Wacker, M., Briggs, A.H., Lloyd, A., Sullivan, S.D., Rutten-van Mölken, M.P.: Cost-effectiveness models for
chronic obstructive pulmonary disease: Cross-model comparison of hypothetical treatment scenarios. Value
Health 17, 525-536 (2014)
Hunger, M.°, Kirchberger, I., Holle, R., Seidl, H., Kuch, B., Wende, R., Meisinger, C.: Does nurse-based
case management for aged myocardial infarction patients improve risk factors, physical functioning and
mental health? The KORINNA trial. Eur. J. Prev. Cardiol. 22, 442-450 (2015) [published online 2014]
Italia, S., Wolfenstetter, S.B., Teuner, C.M.: Patterns of Complementary and Alternative Medicine (CAM)
use in children: A systematic review. Eur. J. Pediatr. 173, 1413-1428 (2014)
page 158 of 247
2015-11-23
#
joint first authors
Kirchberger, I.°, Meisinger, C., Golüke, H., Heier, M., Kuch, B., Peters, A., Quinones, P.A., von Scheidt,
W., Mielck, A.: Long-term survival among older patients with myocardial infarction differs by educational
level: Results from the MONICA/KORA myocardial infarction registry. Int. J. Equity Health 13:19 (2014)
Koerber, F.°, Waidelich, R., Stollenwerk, B., Rogowski, W.H.: The cost-utility of open prostatectomy
compared with active surveillance in early localised prostate cancer. BMC Health Serv. Res. 14:163 (2014)
Korber, K.°: Potential transferability of economic evaluations of programs encouraging physical activity in
children and adolescents across different countries - a systematic review. Int. J. Environ. Res. Public Health
11, 10606-10621 (2014)
Laxy, M., Holle, R.°: Selbstmanagement der Patienten: Intensive Einbindung lohnt. Dtsch. Ärztebl. 111,
20-22 (2014)
(2014)
Little, M.H.R.°, Reitmeir, P., Peters, A., Leidl, R.: The impact of differences between patient and general
population EQ-5D-3L values on the mean tariff scores of different patient groups. Value Health 17, 364-371
(2014)
Maier, W.°, Scheidt-Nave, C., Holle, R., Kroll, L.E., Lampert, T., Du, Y., Heidemann, C., Mielck, A.: Area
level deprivation is an independent determinant of prevalent type 2 diabetes and obesity at the national level
in Germany. Results from the national telephone health interview surveys 'German Health Update' GEDA
2009 and 2010. PLoS ONE 9:e89661 (2014)
Maron, J.°, Hunger, M., Kirchberger, I., Peters, A., Mielck, A., KORA Study Group (Heinrich, J., Holle,
R., Leidl, R., Meisinger, C., Strauch, K.): Nimmt die gesundheitliche Ungleichheit zu?
Maron, J., Mielck, A.°: Nimmt die gesundheitliche Ungleichheit zu? Ergebnisse eines Literaturreviews und
Empfehlungen für die weitere Forschung. Gesundheitswesen 77, 137-147 (2015) [published online 2014]
Mensch, A.°, Stock, S., Stollenwerk, B., Müller, D.: Cost effectiveness of rivaroxaban for stroke prevention
in German patients with atrial fibrillation. Pharmacoeconomics 33, 271-283 (2015) [published online 2014]
Mielck, A.°, Vogelmann, M., Leidl, R.: Health-related quality of life and socioeconomic status: Inequalities
among adults with a chronic disease. Health Qual. Life Outcomes 12:58 (2014)
page 159 of 247
2015-11-23
#
joint first authors
Mueller, M.°, Strobl, R., Jahn, K., Linkohr, B., Ladwig, K.-H., Mielck, A., Grill, E.: Impact of vertigo and
dizziness on self-perceived participation and autonomy in older adults: Results from the KORA-Age study.
Qual. Life Res. 23, 2301-2308 (2014)
Müller, D.J.°, Stock, S., Stollenwerk, B.: Cost-effectiveness of a multifactorial fracture prevention program
for elderly people admitted to nursing homes. Eur. J. Health Econ. 16, 517-527 (2015) [published online
2014]
Pokhrel, S.°, Evers, S., Leidl, R., Trapero-Bertran, M., Kalo, Z., Vries, H.d., Crossfield, A., Andrews, F.,
Rutter, A., Coyle, K., Lester-George, A., West, R., Owen, L., Jones, T., Vogl, M., Radu-Loghin, C., Voko, Z.,
Huic, M., Coyle, D.: EQUIPT: Protocol of a comparative effectiveness research study evaluating
cross-context transferability of economic evidence on tobacco control. BMJ Open 4:e006945 (2014)
Quinones, P.A.°, Kirchberger, I., Heier, M., Kuch, B., Trentinaglia, I., Mielck, A., Peters, A., von Scheidt,
W., Meisinger, C.: Marital status shows a strong protective effect on long-term mortality among first acute
myocardial infarction-survivors with diagnosed hyperlipidemia - findings from the MONICA/KORA Myocardial
Infarction Registry. BMC Public Health 14:98 (2014)
Quinones, P.A.°, Seidl, H., Holle, R., Kuch, B., Meisinger, C., Hunger, M., Kirchberger, I.: New potential
determinants of disability in aged persons with myocardial infarction: Results from the KORINNA-study. BMC
Geriatr. 14:34 (2014)
(2014)
Rogowski, W.H.°, Payne, K., Schnell-Inderst, P., Manca, A., Rochau, U., Jahn, B., Alagoz, O., Leidl, R.,
Siebert, U.: Concepts of 'personalization' in personalized medicine: Implications for economic evaluation.
Pharmacoeconomics 33, 49-59 (2015) [published online 2014]
Rogowski, W.H.°, Schleidgen, S.°: Using needs-based frameworks for evaluating new technologies: An
application to genetic tests. Health Policy 119, 147-155 (2015) [published online 2014]
Rottenkolber, M.°, Rottenkolber, D., Fischer, R., Ibáñez, L., Fortuny, J., Ballarin, E., Sabaté, M., Ferrer, P.,
Thürmann, P., Hasford, J., Schmiedl, S.: Inhaled beta-2-agonists/muscarinic antagonists and acute
myocardial infarction in COPD patients. Respir. Med. 108, 1075-1090 (2014)
Schipf, S°, Ittermann, T., Tamayo, T., Holle, R., Schunk, M., Maier, W., Meisinger, C., Thorand, B., Kluttig,
A., Greiser, K.H., Berger, K., Müller, G., Moebus, S., Slomiany, U., Icks, A., Rathmann, W., Völzke, H.:
Regional differences in the incidence of self-reported type 2 diabetes in Germany: Results from five
population-based studies in Germany (DIAB-CORE Consortium) J. Epidemiol. Community Health 68,
1088-1095 (2014)
page 160 of 247
2015-11-23
#
joint first authors
Schmiedl, S., Rottenkolber, M., Hasford, J., Rottenkolber, D., Farker, K., Drewelow, B., Hippius, M., Saljé,
K., Thürmann, P.°: Self-medication with over-the-counter and prescribed drugs causing
adverse-drug-reaction-related hospital admissions: Results of a prospective, long-term multi-centre study.
Drug Saf. 37, 225-235 (2014)
Schwarzkopf, L.°, Hao, Y., Holle, R., Graessel, E.: Health care service utilization of dementia patients
before and after institutionalization: A claims data analysis. Dement. Geriatr. Cogn. Disord. 4, 195-208
(2014)
Seidl, H.°, Hunger, M., Leidl, R., Meisinger, C., Wende, R., Kuch, B., Holle, R.: Cost-effectiveness of
nurse-based case management versus usual care for elderly patients with myocardial infarction: Results
from the KORINNA study. Eur. J. Health Econ. 16, 671-681 (2015) [published online 2014]
Seidl, H.°, Bowles, D., Bock, J.O., Brettschneider, C., Greiner, W., König, H.H., Holle, R.: FIMA –
Fragebogen zur Erhebung von Gesundheitsleistungen im Alter: Entwicklung und Pilotstudie.
Gesundheitswesen 77, 46-52 (2015) [published online 2014]
Severin, F., Borry, P., Cornel, M.C., Daniels, N., Fellmann, F., Hodgson, S.V., Howard, H.C., John, J.,
Kääriäinen, H., Kayserili, H., Kent, A., Koerber, F., Kristoffersson, U., Kroese, M., Lewis, C.M., Marckmann,
G., Meyer, P., Pfeufer, A., Schmidtke, J., Skirton, H., Tranebjærg, L., Rogowski, W.H.°, EuroGentest
Consortium, ESHG/PPPC Priority Consortium: Points to consider for prioritizing clinical genetic testing
services: European consensus process oriented at accountability for reasonableness. Eur. J. Hum. Genet.
23, 729-735 (2014)
Severin, F.°, Hess, W., Schmidtke, J., Mühlbacher, A., Rogowski, W.H.: Value judgments for priority setting
criteria in genetic testing: A discrete choice experiment. Health Policy 119, 164-173 (2015) [published online
2014]
Siegel, M.°, Mielck, A., Maier, W.: Individual income, area deprivation, and health: Do income-related health
equalities vary by small area deprivation? Health Econ. 24, 1523-1530 (2015) [published online 2014]
Stollenwerk, B., Lhachimi, S.K.°, Briggs, A., Fenwick, E., Caro, J.J., Siebert, U., Danner, M., Gerber-Grote,
A.: Communicating the parameter uncertainty in the IQWIG efficiency frontier to decision-makers. Health
Econ. 24, 481-490 (2014)
Stollenwerk, B., Waldeyer, R., Klein-Meding, C., Müller, D., Stock, S.°: Cost effectiveness of external hip
protectors in the hospital setting: A modeling study. Nurs. Econ. 32, 89-98 (2014)
Strobl, R.°, Maier, W., Mielck, A., Fuchs, J., Richter-Kornweitz, A., Gostomzyk, J.G., Grill, E.: Wohnumfeld Stolperstein oder Weg zum gesunden Altern? : Ergebnisse der Augsburger Regionalkonferenz
"Wohnumfeld, Alter und Gesundheit". Bundesgesundheitsbl.-Gesund. 57, 1120-1126 (2014)
Tamayo, T.°, Schipf, S., Meisinger, C., Schunk, M., Maier, W., Herder, C., Roden, M., Nauck, M., Peters,
A., Völzke, H., Rathmann, W.: Regional differences of undiagnosed type 2 diabetes and prediabetes
prevalence are not explained by known risk factors. PLoS ONE 9:e113154 (2014)
page 161 of 247
2015-11-23
#
joint first authors
Vogl, M.°, Leidl, R., Plötz, W., Gutacker, N.: Comparison of pre- and post-operative health-related quality of
life and length of stay after primary total hip replacement in matched English and German patient cohorts.
Qual. Life Res. 24, 513-520 (2015) [published online 2014]
Vogl, M.°: Hospital financing: Calculating inpatient capital costs in Germany with a comparative view on
operating costs and the English costing scheme. Health Policy 115, 141-151 (2014)
Vogl, M.°, Wilkesmann, R., Lausmann, C., Hunger, M., Ploetz, W.: The impact of preoperative patient
characteristics on health states after total hip replacement and related satisfaction thresholds: A cohort
study. Health Qual. Life Outcomes 12:108 (2014)
Vogl, M.°, Wilkesmann, R., Lausmann, C., Plötz, W.: The impact of preoperative patient characteristics on
the cost-effectiveness of total hip replacement: A cohort study. BMC Health Serv. Res. 14:342 (2014)
Voigtländer, S.°, Vogt, V., Mielck, A., Razum, O.: Explanatory models concerning the effects of small-area
characteristics on individual health. Int. J. Public Health 59, 427-438 (2014)
Weidenhammer, W.°, Lacruz, M.E., Emeny, R.T., Linde, K., Peters, A., Thorand, B., Mielck, A., Ladwig,
K.-H.: Prevalence of use and level of awareness of CAM in older people - results from the KORA-Age study.
Forsch. Komplementmed. 21, 294-301 (2014)
Witt, S., Leidl, R., Becker, C., Holle, R., Block, M., Brachmann, J., Silber, S., Stollenwerk, B.°: The
effectiveness of the cardiovascular disease prevention programme 'KardioPro' initiated by a German
sickness fund: A time-to-event analysis of routine data. PLoS ONE 9:e114720 (2014)
Wu, L., Piotrowski, K., Rau, T.T., Waldmann, E., Broedl, U.C., Demmelmair, H., Koletzko, B., Stark, R.G.,
Nagel, J.M., Mantzoros, C.S., Parhofer, K.G.°: Walnut-enriched diet reduces fasting non-HDL-cholesterol
and apolipoprotein B in healthy Caucasian subjects: A randomized controlled cross-over clinical trial.
Metab.-Clin. Exp. 63, 382-391 (2014)
page 162 of 247
2015-11-23
#
joint first authors
Institute of Human Genetics
Almontashiri, N., Chen, H.-H., Mailloux, R., Tatsuta, T, Teng, A., Mahmoud, A, Ho, T., Stewart, N.A.,
Rippstein, P., Harper, M.E., Roberts, R., Willenborg, C., Erdmann, J., CARDIoGRAM Consortium (Döring,
A., Illig, T., Klopp, N., Meisinger, C., Meitinger, T., Peters, A., Wichmann, H.-E.), Pastore, A., McBride,
H., Langer, T., Stewart, A.F.R.°: SPG7 variant escapes phosphorylation-regulated processing by AFG3L2,
elevates mitochondrial ROS, and is associated with multiple clinical phenotypes. Cell Rep. 7, 834-847 (2014)
page 163 of 247
2015-11-23
#
joint first authors
#
#
Ashraf, S.#, Gee, H.Y.#, Woerner, S., Xie, L.T.X., Vega-Warner, V., Lovric, S., Fang, H., Song, X.W., Cattran,
D.C., Avila-Casado, C., Paterson, A.D., Nitschke, P., Bole-Feysot, C., Cochat, P., Esteve-Rudd, J.,
Haberberger, B., Allen, S.J., Zhou, W.B., Airik, R., Otto, E.A., Barua, M., Al-Hamed, M.H., Kari, J.A., Evans,
J., Bierzynska, A., Saleem, M.A., Bockenhauer, D., Kleta, R., El Desoky, S., Hacihamdioglu, D.O., Gok, F.,
Washburn, J., Wiggins, R.C., Choi, M., Lifton, R.P., Levy, S., Han, Z.G., Salviati, L., Prokisch, H., Williams,
D.S., Pollak, M., Clarke, C.F., Pei, Y., Antignac, C., Hildebrandt, F.°: ADCK4 mutations promote
steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption. J. Clin. Invest. 123, 5179-5189
(2013)
page 164 of 247
2015-11-23
#
joint first authors
Banka, S.°, de Goede, C.G., Yue, W.W., Morris, A.A., von Bremen, B., Chandler, K.E., Feichtinger, R.G.,
Hart, C., Khan, N., Lunzer, V., Matakovic, L., Marquardt, T., Makowski, C.C., Prokisch, H., Debus, O.,
Nosaka, K., Sonwalkar, H., Zimmermann, F.A., Sperl, W.J., Mayr, J.A.: Expanding the clinical and molecular
spectrum of thiamine pyrophosphokinase deficiency: A treatable neurological disorder caused by TPK1
mutations. Mol. Genet. Metab. 113, 301-306 (2014)
Baquero-Montoya, C., Gil-Rodríguez, M.C., Braunholz, D., Teresa-Rodrigo, M.E., Obieglo, C., Gener, B.,
Schwarzmayr, T., Strom, T.M., Gómez-Puertas, P., Puisac, B., Gillessen-Kaesbach, G., Musio, A., Ramos,
F.J., Kaiser, F.J., Pié, J.°: Somatic mosaicism in a Cornelia de Lange syndrome patient with NIPBL mutation
identified by different next generation sequencing approaches. Clin. Genet. 86, 595-597 (2014)
Bari, V., Marchi, A., de Maria, B., Girardengo, G., George, A.L., Brink, P.A., Cerutti, S., Crotti, L., Schwartz,
P.J., Porta, A.: Low-pass filtering approach via empirical mode decomposition improves short-scale
entropy-based complexity estimation of QT interval variability in long QT syndrome type 1 patients. Entropy
16, 4839-4854 (2014)
Bari, V., Valencia, J.F., Vallverdú, M., Girardengo, G., Marchi, A., Bassani, T., Caminal, P., Cerutti, S.,
George, A.L., Brink, P.A., Crotti, L., Schwartz, P.J., Porta, A.°: Multiscale complexity analysis of the cardiac
control identifies asymptomatic and symptomatic patients in long QT syndrome type 1. PLoS ONE 9:e93808
(2014)
Bari, V.°, Bassani, T., Marchi, A., Girardengo, G., Calvillo, L., Cerutti, S., Brink, P.A., Crotti, L., Schwartz,
P.J., Porta, A.: Symbolic analysis of heart period and QT interval variabilities in LQT1 patients. IFMBE Proc.
41, 531-534 (2014)
(2014)
Beryozkin, A., Zelinger, L., Bandah-Rozenfeld, D., Shevach, E., Harel, A., Strom, T.M., Sagi, M., Eli, D.,
Merin, S., Banin, E., Sharon, D.°: Identification of mutations causing inherited retinal degenerations in the
Israeli and Palestinian populations using homozygosity mapping. Invest. Ophthalmol. Vis. Sci. 55, 1149-1160
(2014)
page 165 of 247
2015-11-23
#
joint first authors
#
#
#
#
#
Beuschlein, F. , Fassnacht, M. °, Assié, G. , Calebiro, D. , Stratakis, C.A. , Osswald, A., Ronchi, C.L.,
Wieland, T., Sbiera, S., Faucz, F.R., Schaak, K., Schmittfull, A., Schwarzmayr, T., Barreau, O., Vezzosi,
D., Rizk-Rabin, M., Zabel, U., Szarek, E., Salpea, P., Forlino, A., Vetro, A., Zuffardi, O., Kisker, C., Diener,
S., Meitinger, T., Lohse, M.J., Reincke, M., Bertherat, J., Strom, T.M., Allolio, B.: Constitutive activation of
PKA catalytic subunit in adrenal Cushing's syndrome. N. Engl. J. Med. 370, 1019-1028 (2014)
Boczek, N.J.#, Ye, D.#, Johnson, E.K., Wang, W., Crotti, L., Tester, D.J., Dagradi, F., Mizusawa, Y., Torchio,
M., Alders, M., Giudicessi, J.R., Wilde, A.A.M., Schwartz, P.J., Nerbonne, J.M., Ackerman, M.J.°:
Characterization of SEMA3A-encoded semaphorin as a naturally occurring Kv4.3 protein inhibitor and its
contribution to Brugada syndrome. Circ. Res. 115, 460-469 (2014)
Bürk, K., Kaiser, F.J., Tennstedt, S., Schöls, L., Kreuz, F.R., Wieland, T., Strom, T.M., Büttner, T., Hollstein,
R., Braunholz, D., Plaschke, J., Gillessen-Kaesbach, G., Zühlke, C.°: A novel missense mutation in
CACNA1A evaluated by in silico protein modeling is associated with non-episodic spinocerebellar ataxia with
slow progression. Eur. J. Med. Genet. 57, 207-211 (2014)
Calvillo, L., Spazzolini, C., Vullo, E., Insolia, R., Crotti, L., Schwartz, P.J.°: Propranolol prevents
life-threatening arrhythmias in LQT3 transgenic mice: Implications for the clinical management of LQT3
patients. Heart Rhythm 11, 126-132 (2014)
(2014)
page 166 of 247
2015-11-23
#
joint first authors
Coffee and Caffeine Genetics Consortium, Cornelis, M.C., Byrne, E.M., Esko, T., Nalls, M.A., Ganna, A.,
Paynter, N., Monda, K.L., Amin, N., Fischer, K., Renström, F., Ngwa, J.S., Huikari, V., Cavadino, A., Nolte,
I.M., Teumer, A., Yu, K., Marques-Vidal, P., Rawal, R., Manichaikul, A., Wojczynski, M.K., Vink, J.M., Zhao,
J.H., Burlutsky, G., Lahti, J., Mikkilä, V., Lemaitre, R.N., Eriksson, J., Musani, S.K., Tanaka, T., Geller, F.,
Luan, J., Hui, J., Mägi, R., Dimitriou, M., Garcia, M.E., Ho, W.K., Wright, M.J., Rose, L.M., Magnusson, P.K.,
Pedersen, N.L., Couper, D., Oostra, B.A., Hofman, A., Ikram, M.A., Tiemeier, H.W., Uitterlinden, A.G., van
Rooij, F.J., Barroso, I., Johansson, I., Xue, L., Kaakinen, M., Milani, L., Power, C., Snieder, H., Stolk, R.P.,
Baumeister, S.E., Biffar, R., Gu, F., Bastardot, F., Kutalik, Z., Jacobs, D.R., Forouhi, N.G., Mihailov, E., Lind,
L., Lindgren, C., Michaelsson, K., Morris, A., Jensen, M., Khaw, K.T., Luben, R.N., Wang, J.J., Männisto, S.,
Perälä, M.M., Kähönen, M., Lehtimäki, T., Viikari, J., Mozaffarian, D., Mukamal, K.J., Psaty, B.M., Döring,
A., Heath, A.C., Montgomery, G.W., Dahmen, N., Carithers, T., Tucker, K.L., Ferrucci, L., Boyd, H.A.,
Melbye, M., Treur, J.L., Mellström, D., Hottenga, J.J., Prokopenko, I., Tönjes, A., Deloukas, P., Kanoni, S.,
Lorentzon, M., Houston, D.K., Liu, Y., Danesh, J., Rasheed, A., Mason, M.A., Zonderman, A.B., Franke, L.,
Kristal, B.S., International Parkinson's Disease Genomics Consortium (IPDGC) (Illig, T., Lichtner, P.), North
American Brain Expression Consortium, UK Brain Expression Consortium, Karjalainen, J., Reed, D.R.,
Westra, H.J., Evans, M.K., Saleheen, D., Harris, T.B., Dedoussis, G., Curhan, G., Stumvoll, M., Beilby, J.,
Pasquale, L.R., Feenstra, B., Bandinelli, S., Ordovas, J.M., Chan, A.T., Peters, U., Ohlsson, C., Gieger, C.,
Martin, N.G., Waldenberger, M., Siscovick, D.S., Raitakari, O., Eriksson, J.G., Mitchell, P., Hunter, D.J.,
Kraft, P., Rimm, E.B., Boomsma, D.I., Borecki, I.B., Loos, R.J., Wareham, N.J., Vollenweider, P., Caporaso,
N., Grabe, H.J., Neuhouser, M.L., Wolffenbuttel, B.H., Hu, F.B., Hyppönen, E., Jarvelin, M.R., Cupples, L.A.,
Franks, P.W., Ridker, P.M., van Duijn, C.M., Heiss, G., Metspalu, A., North, K.E., Ingelsson, E., Nettleton,
J.A., van Dam, R.M., Chasman, D.I.°: Genome-wide meta-analysis identifies six novel loci associated with
habitual coffee consumption. Mol. Psychiatry 20, 647-656 (2015) [published online 2014]
Crotti, L.°, Ghidoni, A., Insolia, R., Schwartz, P.J.: The role of the cardiac sodium channel in perinatal early
infant mortality. Card. Electrophysiol. Clin. 6, 749-759 (2014)
Dallabona, C., Diodato, D., Kevelam, S.H., Haack, T.B., Wong, L.J., Salomons, G.S., Baruffini, E.,
Melchionda, L., Mariotti, C., Strom, T.M., Meitinger, T., Prokisch, H., Chapman, K., Colley, A., Rocha, H.,
Ounap, K., Schiffmann, R., Salsano, E., Savoiardo, M., Hamilton, E.M., Abbink, T.E.M., Wolf, N.I., Ferrero, I.,
Lamperti, C., Zeviani, M., Vanderver, A., Ghezzi, D.°, van der Knaap, M.S.°: Novel (ovario) leukodystrophy
related to AARS2 mutations. Neurology 82, 2063-2071 (2014)
de Villiers, C.P.°, van der Merwe, L., Crotti, L., Goosen, A., George, A.L. Jr., Schwartz, P.J., Brink, P.A.,
Moolman-Smook, J.C., Corfield, V.A.: AKAP9 is a genetic modifier of congenital long-QT syndrome type 1.
Circ. Cardiovasc. Genet. 7, 599-606 (2014)
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#
Derikx, M.H. , Kovacs, P. , Scholz, M. , Masson, E. , Chen, J.M., Ruffert, C., Lichtner, P., Te Morsche,
R.H., Cavestro, G.M., PanEuropean Working group on Alcoholic Chronic Pancreatitis, Férec, C., Drenth,
#
J.P. , Witt, H., Rosendahl, J.°: Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with
alcoholic and non-alcoholic chronic pancreatitis in a European replication study. Gut 64, 1426-1433 (2015)
page 167 of 247
2015-11-23
#
joint first authors
#
#
Diodato, D. , Melchionda, L. , Haack, T.B., Dallabona, C., Baruffini, E., Donnini, C., Granata, T., Ragona, F.,
Balestri, P., Margollicci, M., Lamantea, E., Nasca, A., Powell, C.A., Minczuk, M., Strom, T.M., Meitinger, T.,
Prokisch, H., Lamperti, C., Zeviani, M., Ghezzi, D.°: VARS2 and TARS2 mutations in patients with
mitochondrial encephalomyopathies. Hum. Mutat. 35, 983-989 (2014)
Dusi, S., Valletta, L., Haack, T.B., Tsuchiya, Y., Venco, P., Pasqualato, S., Goffrini, P., Tigano, M.,
Demchenko, N., Wieland, T., Schwarzmayr, T., Strom, T.M., Invernizzi, F., Garavaglia, B., Gregory, A.,
Sanford, L., Hamada, J., Bettencourt, C., Houlden, H., Chiapparini, L., Zorzi, G., Kurian, M.A., Nardocci, N.,
Prokisch, H., Hayflick, S., Gout, I., Tiranti, V.°: Exome sequence reveals mutations in CoA synthase as a
cause of neurodegeneration with brain iron accumulation. Am. J. Hum. Genet. 94, 11-22 (2014)
#
#
Eichenmüller, M. , Trippel, F. , Kreuder, M., Beck, A., Schwarzmayr, T., Häberle, B., Cairo, S., Leuschner,
I., von Schweinitz, D., Strom, T.M., German Cancer Consortium (DKTK), Heidelberg, (Kappler, R.°): The
genomic landscape of hepatoblastoma and their progenies with HCC-like features. J. Hepatol. 61,
1312-1320 (2014)
Fernandes-Rosa, F.L.#, Williams, T.A.#, Riester, A.#, Steichen, O., Beuschlein, F., Boulkroun, S., Strom,
T.M., Monticone, S., Amar, L., Meatchi, T., Mantero, F., Cicala, M.V., Quinkler, M., Fallo, F., Allolio, B.,
Bernini, G., Maccario, M., Giacchetti, G., Jeunemaitre, X., Mulatero, P.#, Reincke, M.#, Zennaro, M.C.°:
Genetic spectrum and clinical correlates of somatic mutations in aldosterone-producing adenoma.
Hypertension 64, 354-361 (2014)
Fischer, D., Schabhüttl, M., Wieland, T., Windhager, R., Strom, T.M., Auer-Grumbach, M.°: A novel
missense mutation confirms ATL3 as a gene for hereditary sensory neuropathy type 1. Brain 137:e286
(2014)
357-363 (2014)
9:e105116 (2014)
page 168 of 247
2015-11-23
#
joint first authors
#
#
Frey, U.H. °, Muehlschlegel, J.D. , Ochterbeck, C., Fox, A.A., Shernan, S.K., Collard, C.D., Lichtner, P.,
Peters, J., Body, S.: GNAS gene variants affect β-blocker-related survival after coronary artery bypass
grafting. Anesthesiology 120, 1109-1117 (2014)
Gess, B.°, Auer-Grumbach, M., Schirmacher, A., Strom, T.M., Zitzelsberger, M., Rudnik-Schöneborn, S.,
Röhr, D., Halfter, H., Young, P., Senderek, J.: HSJ1-related hereditary neuropathies: Novel mutations and
extended clinical spectrum. Neurology 83, 1726-1732 (2014)
Haack, T.B., Klee, D., Strom, T.M., Mayatepek, E., Meitinger, T., Prokisch, H.°, Distelmaier, F.°: Infantile
Leigh-like syndrome caused by SLC19A3 mutations is a treatable disease. Brain 137:e295 (2014)
Haack, T.B., Gorza, M., Danhauser, K., Mayr, J.A., Haberberger, B., Wieland, T., Kremer, L.S., Strecker,
V., Graf, E., Memari, Y., Ahting, U., Kopajtich, R., Wortmann, S.B., Rodenburg, R.J., Kotzaeridou, U.,
Hoffmann, G.F., Sperl, W., Wittig, I., Wilichowski, E., Schottmann, G., Schuelke, M., Plecko, B., Stephani, U.,
Strom, T.M., Meitinger, T., Prokisch, H., Freisinger, P.°: Phenotypic spectrum of eleven patients and five
novel MTFMT mutations identified by exome sequencing and candidate gene screening. Mol. Genet. Metab.
111, 342-352 (2014)
Haghighi, A.°, Haack, T.B., Atiq, M., Mottaghi, H., Haghighi-Kakhki, H., Bashir, R.A., Ahting, U., Feichtinger,
R.G., Mayr, J.A., Rotig, A., Lebre, A.S., Klopstock, T., Dworschak, A., Pulido, N., Saeed, M.A., Saleh-Gohari,
N., Holzerova, E., Chinnery, P.F., Taylor, R.W., Prokisch, H.: Sengers syndrome: Six novel AGK mutations
in seven new families and review of the phenotypic and mutational spectrum of 29 patients. Orphanet J.
Rare Dis. 9:119 (2014)
Han, F., Lin, L., Schormair, B., Pizza, F., Plazzi, G., Ollila, H.M., Nevsimalova, S., Jennum, P., Knudsen, S.,
Winkelmann, J., Coquillard, C., Babrzadeh, F., Strom, T.M., Wang, C., Mindrinos, M., Vina, M.F., Mignot,
E.°: HLA DQB1*06:02 negative narcolepsy with hypocretin/orexin deficiency. Sleep 37, 1601-1608 (2014)
Hartiala, J., Bennett, B.J., Tang, W.H.W., Wang, Z., Stewart, A.F.R., Roberts, R., McPherson, R.,
CARDIoGRAM Consortium (Döring, A., Illig, T., Klopp, N., Meisinger, C., Meitinger, T., Peters, A.,
Wichmann, H.-E.), Lusis, A., Hazen, S.L., Allayee, H.°: Comparative genome-wide association studies in
mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and l-carnitine.
Arterioscler. Thromb. Vasc. Biol. 34, 1307-1313 (2014)
Hennessey, J.A., Marcou, C.A., Wang, C., Wei, E.Q., Wang, C.J., Tester, D.J., Torchio, M., Dagradi, F.,
Crotti, L., Schwartz, P.J., Ackerman, M.J., Pitt, G.S.°: FGF12 is a candidate Brugada syndrome locus. Heart
Rhythm 10, 1886-1894 (2013)
page 169 of 247
2015-11-23
#
joint first authors
#
#
#
4343-4359 (2014)
Hermann, M.M., van Asten, F., Muether, P.S., Smailhodzic, D., Lichtner, P., Hoyng, C.B., Kirchhof, B.,
Grefkes, C., den Hollander, A.I., Fauser, S.°: Polymorphisms in vascular endothelial growth factor receptor 2
are associated with better response rates to ranibizumab treatment in age-related macular degeneration.
Ophthalmology 121, 905-910 (2014)
Holmes, M.V., Exeter, H.J., Folkersen, L., Nelson, C.P., Guardiola, M., Cooper, J.A., Sofat, R., Boekholdt,
S.M., Khaw, K.T., Li, K.W., Smith, A.J., van't Hooft, F.M., Eriksson, P., Franco-Cereceda, A., Asselbergs,
F.W., Boer, J.M., Onland-Moret, N.C., Hofker, M.H., Erdmann, J., Kivimaki, M., Kumari, M., Reiner, A.P.,
Keating, B.J., Humphries, S.E., Hingorani, A.D., Mallat, Z., Samani, N.J., Talmud, P.J.°, CARDIoGRAM
Consortium (Döring, A., Illig, T., Klopp, N., Meisinger, C., Meitinger, T., Peters, A., Wichmann, H.-E.):
Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA(2))-V isoenzyme
in coronary heart disease modified mendelian randomization analysis using PLA2G5 expression levels. Circ.
Cardiovasc. Genet. 7, 144-150 (2014)
Iuso, A., Sibon, O.C., Gorza, M., Heim, K., Organisti, C., Meitinger, T., Prokisch, H.°: Impairment of
Drosophila orthologs of the human orphan protein c19orf12 induces bang sensitivity and neurodegeneration.
PLoS ONE 9:e89439 (2014)
#
#
Jackson, C.B. , Nuoffer, J.-M. , Hahn, D., Prokisch, H., Haberberger, B., Gautschi, M., Häberli, A., Gallati,
S., Schaller, A.°: Mutations in SDHD lead to autosomal recessive encephalomyopathy and isolated
mitochondrial complex II deficiency. J. Med. Genet. 51, 170-175 (2014) [published online 2013]
systemic phenotypic analysis of Slc12a1 I299F mutant mice. J. Biomed. Sci. 21:68 (2014)
page 170 of 247
2015-11-23
#
joint first authors
Khan, S., Greco, D., Michailidou, K., Milne, R.L., Muranen, T.A., Heikkinen, T., Aaltonen, K., Dennis, J.,
Bolla, M.K., Liu, J., Hall, P., Irwanto, A., Humphreys, K., Li, J., Czene, K., Chang-Claude, J., Hein, R.,
Rudolph, A., Seibold, P., Flesch-Janys, D., Fletcher, O., Peto, J., Dos Santos Silva, I., Johnson, N., Gibson,
L., Aitken, Z., Hopper, J.L., Tsimiklis, H., Bui, M., Makalic, E., Schmidt, D.F., Southey, M.C., Apicella, C.,
Stone, J., Waisfisz, Q., Meijers-Heijboer, H., Adank, M.A., van der Luijt, R.B., Meindl, A., Schmutzler, R.K.,
Müller-Myhsok, B., Lichtner, P., Turnbull, C., Rahman, N., Chanock, S.J., Hunter, D.J., Cox, A., Cross, S.S.,
Reed, M.W., Schmidt, M.K., Broeks, A., Veer, L.J., Hogervorst, F.B., Fasching, P.A., Schrauder, M.G., Ekici,
A.B., Beckmann, M.W., Bojesen, S.E., Nordestgaard, B.G., Nielsen, S.F., Flyger, H., Benítez, J., Zamora,
P.M., Perez, J.I.A., Haiman, C.A., Henderson, B.E., Schumacher, F., Le Marchand, L., Pharoah, P.D.,
Dunning, A.M., Shah, M., Luben, R., Brown, J., Couch, F.J., Wang, X., Vachon, C., Olson, J.E., Lambrechts,
D., Moisse, M., Paridaens, R., Christiaens, M.R., Guénel, P., Truong, T., Laurent-Puig, P., Mulot, C., Marme,
F., Burwinkel, B., Schneeweiss, A., Sohn, C., Sawyer, E.J., Tomlinson, I., Kerin, M.J., Miller, N., Andrulis,
I.L., Knight, J.A., Tchatchou, S., Mulligan, A.M., Dörk, T., Bogdanova, N.V., Antonenkova, N.N.,
Anton-Culver, H., Darabi, H., Eriksson, M., Garcia-Closas, M., Figueroa, J., Lissowska, J., Brinton, L.,
Devilee, P., Tollenaar, R.A., Seynaeve, C., van Asperen, C.J., Kristensen, V.N., Slager, S., Toland, A.E.,
Ambrosone, C.B., Yannoukakos, D., Lindblom, A., Margolin, S., Radice, P., Peterlongo, P., Barile, M.,
Mariani, P., Hooning, M.J., Martens, J.W.M., Collee, J.M., Jäger, A., Jakubowska, A., Lubinski, J.,
Jaworska-Bieniek, K., Durda, K., Giles, G.G., McLean, C., Brauch, H., Brüning, T., Ko, Y.D., Brenner, H.,
Dieffenbach, A.K., Arndt, V., Stegmaier, C., Swerdlow, A., Ashworth, A., Orr, N., Jones, M., Simard, J.,
Goldberg, M.S., Labreche, F., Dumont, M., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Kataja,
V., Kosma, V.M., Hartikainen, J.M., Mannermaa, A., Hamann, U., Chenevix-Trench, G., Blomqvist, C.,
Aittomäki, K., Easton, D.F., Nevanlinna, H.°: MicroRNA related polymorphisms and breast cancer risk. PLoS
ONE 9:e109973 (2014)
Kopajtich, R.#, Nicholls, T.J.#, Rorbach, J.#, Metodiev, M.D.#, Freisinger, P., Mandel, H., Vanlander, A.,
Ghezzi, D., Carrozzo, R., Taylor, R.W., Marquard, K., Murayama, K., Wieland, T., Schwarzmayr, T., Mayr,
J.A., Pearce, S.F., Powell, C.A., Saada, A., Ohtake, A., Invernizzi, F., Lamantea, E., Sommerville, E.W.,
Pyle, A., Chinnery, P.F., Crushell, E., Okazaki, Y., Kohda, M., Kishita, Y., Tokuzawa, Y., Assouline, Z., Rio,
M., Feillet, F., Mousson de Camaret, B., Chretien, D., Munnich, A., Menten, B., Sante, T., Smet, J., Régal, L.,
Lorber, A., Khoury, A., Zeviani, M., Strom, T.M., Meitinger, T., Bertini, E.S., van Coster, R., Klopstock, T.,
Rotig, A., Haack, T.B., Minczuk, M.°, Prokisch, H.°: Mutations in GTPBP3 cause a mitochondrial translation
defect associated with hypertrophic cardiomyopathy, lactic acidosis, and encephalopathy. Am. J. Hum.
Genet. 59, 708-720 (2014)
page 171 of 247
2015-11-23
#
joint first authors
Kuechler, A.°, Willemsen, M.H., Albrecht, B., Bacino, C.A., Bartholomew, D.W., van Bokhoven, H., van den
Boogaard, M.J., Bramswig, N., Büttner, C., Cremer, K., Czeschik, J.C., Engels, H., van Gassen, K., Graf, E.,
van Haelst, M.M., He, W., Hogue, J.S., Kempers, M., Koolen, D.A., Monroe, G., de Munnik, S., Pastore, M.,
Reis, A., Reuter, M.S., Tegay, D.H., Veltman, J.A., Visser, G., van Hasselt, P., Smeets, E.E., Vissers, L.E.,
Wieland, T., Wissink, W., Yntema, H., Zink, A.M., Strom, T.M., Lüdecke, H.J., Kleefstra, T., Wieczorek, D.:
De novo mutations in beta-catenin (CTNNB1) appear to be a frequent cause of intellectual disability:
Expanding the mutational and clinical spectrum. Hum. Genet. 134, 97-109 (2015) [published online 2014]
Kuechler, A., Zink, A.M., Wieland, T., Lüdecke, H.J., Cremer, K., Salviati, L., Magini, P., Najafi, K., Zweier,
C., Czeschik, J.C., Aretz, S., Endele, S., Tamburrino, F., Pinato, C., Clementi, M., Gundlach, J., Maylahn,
C., Mazzanti, L., Wohlleber, E., Schwarzmayr, T., Kariminejad, R., Schlessinger, A., Wieczorek, D., Strom,
T.M., Novarino, G., Engels, H.°: Loss-of-function variants of SETD5 cause intellectual disability and the core
phenotype of microdeletion 3p25.3 syndrome. Eur. J. Hum. Genet. 23, 753-760 (2014)
Kurz, C.°, Wunderlich, S., Spieler, D., Schwaiger, B.J., Andres, C., Traidl-Hoffmann, C., Ilg, R.: Acute
transverse myelitis and psoriasiform dermatitis associated with Sjoegren's syndrome: A case report. BMC
Res. Notes 7:580 (2014)
page 172 of 247
2015-11-23
#
joint first authors
#
#
#
Lange, L.A. , Hu, Y. , Zhang, H. , Xue, C., Schmidt, E.M., Tang, Z.Z., Bizon, C., Lange, E.M., Smith, J.D.,
Turner, E.H., Jun, G., Kang, H.M., Peloso, G., Auer, P., Li, K.P., Flannick, J., Zhang, J., Fuchsberger, C.,
Gaulton, K., Lindgren, C., Locke, A., Manning, A., Sim, X., Rivas, M.A., Holmen, O.L., Gottesman, O., Lu, Y.,
Ruderfer, D., Stahl, E.A., Duan, Q., Li, Y., Durda, P., Jiao, S., Isaacs, A., Hofman, A., Bis, J.C., Correa, A.,
Griswold, M.E., Jakobsdottir, J., Smith, A.V., Schreiner, P.J., Feitosa, M.F., Zhang, Q., Huffman, J.E.,
Crosby, J., Wassel, C.L., Do, R., Franceschini, N., Martin, L.W., Robinson, J.G., Assimes, T.L., Crosslin,
D.R., Rosenthal, E.A., Tsai, M., Rieder, M.J., Farlow, D.N., Folsom, A.R., Lumley, T., Fox, E.R., Carlson,
C.S., Peters, U., Jackson, R.D., van Duijn, C.M., Uitterlinden, A.G., Levy, D., Rotter, J.I., Taylor, H.A.,
Gudnason, V., Siscovick, D.S., Fornage, M., Borecki, I.B., Hayward, C., Rudan, I., Chen, Y.E., Bottinger,
E.P., Loos, R.J., Sætrom, P., Hveem, K., Boehnke, M., Groop, L., McCarthy, M., Meitinger, T., Ballantyne,
C.M., Gabriel, S.B., O'Donnell, C.J., Post, W.S., North, K.E., Reiner, A.P., Boerwinkle, E., Psaty, B.M.,
Altshuler, D., Kathiresan, S., Lin, D.Y., Jarvik, G.P., Cupples, L.A., Kooperberg, C., Wilson, J.G., Nickerson,
D.A., Abecasis, G.R., Rich, S.S., Tracy, R.P., Willer, C.J.°, NHLBI Grand Opportunity Exome Sequencing
Project: Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL
cholesterol. Am. J. Hum. Genet. 94, 233-245 (2014)
Makita, N., Yagihara, N., Crotti, L., Johnson, C.N., Beckmann, B.M., Roh, M.S., Shigemizu, D., Lichtner, P.,
Ishikawa, T., Aiba, T., Homfray, T., Behr, E.R., Klug, D., Denjoy, I., Mastantuono, E., Theisen, D., Tsunoda,
T., Satake, W., Toda, T., Nakagawa, H., Tsuji, Y., Tsuchiya, T., Yamamoto, H., Miyamoto, Y., Endo, N.,
Kimura, A., Ozaki, K., Motomura, H., Suda, K., Tanaka, T., Schwartz, P.J., Meitinger, T., Kääb, S.,
Guicheney, P., Shimizu, W., Bhuiyan, Z.A., Watanabe, H., Chazin, W.J., George, A.L.°: Novel calmodulin
(CALM2) mutations associated with congenital arrhythmia susceptibility. Circ. Cardiovasc. Genet. 7, 466-474
(2014)
page 173 of 247
2015-11-23
#
joint first authors
#
#
#
Medici, M. °, Porcu, E. , Pistis, G. , Teumer, A., Brown, S.J., Jensen, R.A., Rawal, R., Roef, G.L., Plantinga,
Melchionda, L., Haack, T.B., Hardy, S., Abbink, T.E.M., Fernandez-Vizarra, E., Lamantea, E., Marchet, S.,
Morandi, L., Moggio, M., Carrozzo, R., Torraco, A., Diodato, D., Strom, T.M., Meitinger, T., Tekturk, P.,
Yapici, Z., Al-Murshedi, F., Stevens, R., Rodenburg, R.J., Lamperti, C., Ardissone, A., Moroni, I., Uziel, G.,
Prokisch, H., Taylor, R.W., Bertini, E., van der Knaap, M.S., Ghezzi, D.°, Zeviani, M.: Mutations in APOPT1,
encoding a mitochondrial protein, cause cavitating leukoencephalopathy with cytochrome c oxidase
deficiency. Am. J. Hum. Genet. 95, 315-325 (2014)
Müller, K., Andersen, P.M., Hübers, A., Marroquin, N., Volk, A.E., Danzer, K.M., Meitinger, T., Ludolph,
A.C., Strom, T.M., Weishaupt, J.H.°: Two novel mutations in conserved codons indicate that CHCHD10 is a
gene associated with motor neuron disease. Brain 137:e309 (2014)
Müller-Höcker, J., Schäfer, S.G., Krebs, S., Blum, H., Zsurka, G., Kunz, W.S., Prokisch, H., Seibel, P., Jung,
A.°: Oxyphil cell metaplasia in the parathyroids is characterized by somatic mitochondrial DNA mutations in
NADH dehydrogenase genes and cytochrome c oxidase activity-impairing genes. Am. J. Pathol. 184,
2922-2935 (2014)
Navon Elkan, P., Pierce, S.B., Segel, R., Walsh, T., Barash, J., Padeh, S., Zlotogorski, A., Berkun, Y., Press,
J.J., Mukamel, M., Voth, I., Hashkes, P.J., Harel, L., Hoffer, V., Ling, E., Yalcinkaya, F., Kasapcopur, O., Lee,
M.K., Klevit, R.E., Renbaum, P., Weinberg-Shukron, A., Sener, E.F., Schormair, B., Zeligson, S.,
Marek-Yagel, D., Strom, T.M., Shohat, M., Singer, A., Rubinow, A., Pras, E., Winkelmann, J., Tekin, M.,
Anikster, Y., King, M.C., Levy-Lahad, E.°: Mutant adenosine deaminase 2 in a polyarteritis nodosa
vasculopathy. N. Engl. J. Med. 370, 921-931 (2014)
page 174 of 247
2015-11-23
#
joint first authors
Nyholt, D.R., Palotie, A., Anttila, V., Winsvold, B.S., Kurth, T., Stefansson, H., Kallela, M., Malik, R., Vries,
B.D., Terwindt, G.M., Ikram, M.A., Stam, A.H., Ligthart, L., Freilinger, T., Alexander, M., Müller-Myhsok, B.,
Schreiber, S., Meitinger, T., Aromaa, A., Eriksson, J.G., Kaprio, J., Boomsma, D.I., van Duijn, C., Raitakari,
O., Jarvelin, M.R., Zwart, J.A., Quaye, L., Strachan, D.P., Kubisch, C., Ferrari, M.D., van den Maagdenberg,
A.M., Dichgans, M., Wessman, M., Smith, G.D., Stefansson, K., Chasman, D.I.°: Concordance of genetic risk
across migraine subgroups: Impact on current and future genetic association studies. Cephalalgia 35,
Oláhová, M., Haack, T.B., Alston, C.L., Houghton, J.A., He, L., Morris, A.A., Brown, G.K., McFarland, R.,
Chrzanowska-Lightowlers, Z.M., Lightowlers, R.N., Prokisch, H., Taylor, R.W.°: A truncating PET100 variant
causing fatal infantile lactic acidosis and isolated cytochrome c oxidase deficiency. Eur. J. Hum. Genet. 23,
#
#
Opherk, C. , Gonik, M. , Duering, M., Malik, R., Jouvent, E., Hervé, D., Adib-Samii, P., Bevan, S., Pianese,
L., Silvestri, S., Dotti, M.T., De Stefano, N., Liem, M., Boon, E.M., Pescini, F., Pachai, C., Bracoud, L.,
Müller-Myhsok, B., Meitinger, T., Rost, N., Pantoni, L., Oberstein, S.L., Federico, A., Ragno, M., Markus,
H.S., Tournier-Lasserve, E., Rosand, J., Chabriat, H., Dichgans, M.°: Genome-wide genotyping
demonstrates a polygenic risk score associated with white matter hyperintensity volume in CADASIL. Stroke
45, 968-972 (2014)
Pekkarinen, T.A.°, Lorenz-Depiereux, B., Lohman, M., Mäkitie, O.M.: Unusually severe hypophosphatemic
rickets caused by a novel and complex re-arrangement of the PHEX gene. Am. J. Med. Genet. A 164,
2931-2937 (2014)
#
#
Pichler, I. , del Greco, M.F. , Gögele, M., Lill, C.M., Bertram, L., Do, C.B., Eriksson, N., Foroud, T., Myers,
R.H., PD GWAS Consortium, Nalls, M., Keller, M.F., International Parkinson's Disease Genomics
Consortium (IPDGC) (Illig, T., Lichtner, P., Winkelmann, J.), Wellcome Trust Case Consortium (WTCCC),
Benyamin, B., Whitfield, J.B., Genetics of Iron Status Consortium, Pramstaller, P.P., Hicks, A.A., Thompson,
J.R., Minelli, C.°: Serum iron levels and the risk of Parkinson disease: A mendelian randomization study.
PLoS Med. 10:e1001462 (2013)
Platzer, K., Hüning, I., Obieglo, C., Schwarzmayr, T., Gabriel, R., Strom, T.M., Gillessen- Kaesbach, G.,
Kaiser, F.J.°: Exome sequencing identifies compound heterozygous mutations in C12orf57 in two siblings
with severe intellectual disability, hypoplasia of the corpus callosum, chorioretinal coloboma, and intractable
seizures. Am. J. Med. Genet. A 164, 1976-1980 (2014)
Qanbari, S.°, Pausch, H., Jansen, S., Somel, M., Strom, T.M., Fries, R., Nielsen, R., Simianer, H.: Classic
selective sweeps revealed by massive sequencing in cattle. PLoS Genet. 10:e1004148 (2014)
Reincke, M.#°, Sbiera, S.#, Hayakawa, A.#, Theodoropoulou, M.#, Osswald, A., Beuschlein, F., Meitinger, T.,
Mizuno-Yamasaki, E., Kawaguchi, K., Saeki, Y., Tanaka, K., Wieland, T., Graf, E., Saeger, W., Ronchi, C.L.,
Allolio, B., Buchfelder, M., Strom, T.M., Fassnacht, M.°, Komada, M.: Mutations in the deubiquitinase gene
USP8 cause Cushing's disease. Nat. Genet. 47, 31-38 (2015) [published online 2014]
page 175 of 247
2015-11-23
#
joint first authors
#
#
Rorbach, J., Boesch, P., Gammage, P.A., Nicholls, T.J.J., Pearce, S.F., Patel, D., Hauser, A., Perocchi, F.,
Minczuk, M.°: MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial
ribosome. Mol. Biol. Cell 25, 2542-2555 (2014)
Savastano, S., Rordorf, R., Vicentini, A., Petracci, B., Taravelli, E., Castelletti, S., D'Errico, A., Torchio, M.,
Dossena, C., Novara, P., Dagradi, F., Landolina, M., Spazzolini, C., Crotti, L., Schwartz, P.J.°: A
comprehensive electrocardiographic, molecular and echocardiographic study of the Brugada Syndrome:
Validation of the 2013 diagnostic criteria. Heart Rhythm 11, 1176-1183 (2014)
Schabhüttl, M., Wieland, T., Senderek, J., Baets, J., Timmerman, V., de Jonghe, P., Reilly, M.M.,
Stieglbauer, K., Laich, E., Windhager, R., Erwa, W., Trajanoski, S., Strom, T.M., Auer-Grumbach, M.°:
Whole-exome sequencing in patients with inherited neuropathies: Outcome and challenges. J. Neurol. 261,
970-982 (2014)
#
#
#
#
Schramm, K. , Marzi, C. , Schurmann, C. , Carstensen, M. , Reinmaa, E., Biffar, R., Eckstein, G.N.,
page 176 of 247
2015-11-23
#
joint first authors
#
#
Schulte, E.C. , Kousi, M. , Tan, P.L., Tilch, E., Knauf, F., Lichtner, P., Trenkwalder, C., Högl, B.,
Shafique, S.#, Siddiqi, S.#, Schraders, M., Oostrik, J., Ayub, H., Bilal, A., Ajmal, M., Seco, C.Z., Strom, T.M.,
Mansoor, A., Mazhar, K., Shah, S.T., Hussain, A., Azam, M., Kremer, H.°, Qamar, R.: Genetic spectrum of
autosomal recessive non-syndromic hearing loss in Pakistani families. PLoS ONE 9:e100146 (2014)
ONE 9:e107110 (2014)
Struhal, W.°, Presslauer, S., Spielberger, S., Zimprich, A., Auff, E., Bruecke, T., Poewe, W.H., Ransmayr,
G.N., Wolf, E.L., Seppi, K., Schmidegg, S., Guger, M., Steffelbauer, M., Javor, A., Hoedl, S., Tomantschger,
V., Grantl-Pühringer, H., Fahrner, A., Hoegler, S., Memelauer, F., Strom, T.M.: VPS35 Parkinson's disease
phenotype resembles the sporadic disease. J. Neural Transm. 121, 755-759 (2014)
Synofzik, M.#°, Gonzalez, M.A.#, Lourenco, C.M.#, Coutelier, M., Haack, T.B., Rebelo, A., Hannequin, D.,
Strom, T.M., Prokisch, H., Kernstock, C., Durr, A., Schöls, L., Lima-Martínez, M.M., Farooq, A., Schüle, R.,
Stevanin, G., Marques, W., Zuchner, S.°: PNPLA6 mutations cause Boucher-Neuhauser and Gordon
Holmes syndromes as part of a broad neurodegenerative spectrum. Brain 137, 69-77 (2014)
#
#
#
Synofzik, M. °, Haack, T.B. , Kopajtich, R. , Gorza, M., Rapaport, D., Greiner, M., Schönfeld, C., Freiberg,
C., Schorr, S., Holl, R.W., Gonzalez, M.A., Fritsche, A., Fallier-Becker, P., Zimmermann, R., Strom, T.M.,
Meitinger, T., Zuchner, S., Schule, R., Schöls, L.°, Prokisch, H.: Absence of BiP co-chaperone DNAJC3
causes diabetes mellitus and multisystemic neurodegeneration. Am. J. Hum. Genet. 95, 689-697 (2014)
page 177 of 247
2015-11-23
#
joint first authors
Synofzik, M.°, Kernstock, C., Haack, T.B., Schöls, L.: Ataxia meets chorioretinal dystrophy and
hypogonadism: Boucher-Neuhäuser syndrome due to PNPLA6 mutations. J. Neurol. Neurosurg. Psychiatr.
Texier, Y., Toedt, G., Gorza, M., Mans, D.A., van Reeuwijk, J., Horn, N., Willer, J., Katsanis, N., Roepman,
R., Gibson, T.J., Ueffing, M., Boldt, K.°: Elution profile analysis of SDS-induced subcomplexes by
quantitative mass spectrometry. Mol. Cell. Proteomics 13, 1382-1391 (2014)
Unterseer, S., Bauer, E., Haberer, G., Seidel, M., Knaak, C., Ouzunova, M., Meitinger, T., Strom, T.M.,
Fries, R., Pausch, H., Bertani, C., Davassi, A., Mayer, K.F.X., Schön, C.C.°: A powerful tool for genome
analysis in maize: Development and evaluation of the high density 600k SNP genotyping array. BMC
Genomics 15:823 (2014)
van der Zee, J., van Langenhove, T., Kovacs, G.G., Dillen, L., Deschamps, W., Engelborghs, S., Matěj, R.,
Vandenbulcke, M., Sieben, A., Dermaut, B., Smets, K., van Damme, P.V., Merlin, C., Laureys, A., van den
Broeck, M.V., Mattheijssens, M., Peeters, K., Benussi, L., Binetti, G., Ghidoni, R., Borroni, B., Padovani, A.,
Archetti, S., Pastor, P., Razquin, C., Ortega-Cubero, S., Hernández, I., Boada, M., Ruiz, A., de Mendonca,
A., Miltenberger-Miltényi, G., do Couto, F.S., Sorbi, S., Nacmias, B., Bagnoli, S., Graff, C., Chiang, H.,
Thonberg, H., Perneczky, R., Diehl-Schmid, J., Alexopoulos, P., Frisoni, G.B., Bonvicini, C., Synofzik, M.,
Maetzler, W., Vom Hagen, J.M., Schöls, L., Haack, T.B., Strom, T.M., Prokisch, H., Dols-Icardo, O.,
Clarimõn, J., Lleõ, A., Santana, I., Almeida, M.R., Santiago, B., Heneka, M.T., Jessen, F., Ramirez, A.,
Sánchez-Valle, R., Lladó, A., Gelpi, E., Sarafov, S., Tournev, I., Jordanova, A., Parobková, E., Fabrizi, G.M.,
Testi, S., Salmon, E., Ströbel, T., Santens, P., Robberecht, W., de Jonghe, P., Martín, J.J.R., Cras, P.,
Vandenberghe, R.R.C., de Deyn, P.P., Cruts, M., Sleegers, K., van Broeckhoven, C.L.°: Rare mutations in
SQSTM1 modify susceptibility to frontotemporal lobar degeneration. Acta Neuropathol. 128, 397-410 (2014)
Am. J. Hum. Genet. 94, 710-720 (2014)
Wieczorek, D.#°, Newman, W.G.#, Wieland, T., Berulava, T., Kaffe, M., Falkenstein, D., Beetz, C., Graf, E.,
Schwarzmayr, T., Douzgou, S., Clayton-Smith, J., Daly, S.B., Williams, S.G., Bhaskar, S.S., Urquhart, J.E.,
Anderson, B., O'Sullivan, J., Boute, O., Gundlach, J., Czeschik, J.C., van Essen, A.J., Hazan, F., Park, S.,
Hing, A., Kuechler, A., Lohmann, D.R., Ludwig, K.U., Mangold, E., Steenpaß, L., Zeschnigk, M., Lemke, J.R.,
Lourenco, C.M., Hehr, U., Prott, E.C., Waldenberger, M., Böhmer, A.C., Horsthemke, B., O'Keefe, R.T.,
Meitinger, T., Burn, J., Lüdecke, H.J., Strom, T.M.: Compound heterozygosity of low-frequency promoter
deletions and rare loss-of-function mutations in TXNL4A causes Burn-McKeown syndrome. Am. J. Hum.
Genet. 95, 698-707 (2014)
page 178 of 247
2015-11-23
#
joint first authors
page 179 of 247
2015-11-23
#
joint first authors
height. Nat. Genet. 46, 1173-1186 (2014)
Yin, G.#, Hassan, F.#, Haroun, A.R., Murphy, L.L., Crotti, L., Schwartz, P.J., George, A.L. Jr., Satin, J.°:
Arrhythmogenic calmodulin mutations disrupt intracellular cardiomyocyte Ca2+ regulation by distinct
mechanisms. J. Am. Heart Assoc. 3:e000996 (2014)
#
#
Zech, M. , Castrop, F. , Schormair, B., Jochim, A., Wieland, T., Gross, N., Lichtner, P., Peters, A.,
(2014)
page 180 of 247
2015-11-23
#
joint first authors
Institute of Lung Biology
Aanerud, M.°, Carsin, A.E., Sunyer, J., Dratva, J., Gislason, T., Jarvis, D., deMarco, R., Raherison, C., Wjst,
M., Dharmage, S.C., Svanes, C.: Interaction between asthma and smoking increases the risk of adult airway
obstruction. Eur. Respir. J. 45, 635-643 (2015) [published online 2014]
Ballweg, K., Mutze, K., Königshoff, M., Eickelberg, O., Meiners, S.°: Cigarette smoke extract affects
mitochondrial function in alveolar epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol. 307, 895-907 (2014)
Banon-Maneus, E.°, Rovira, J., Ramirez-Bajo, M.J., Moya-Rull, D., Hierro-Garcia, N., Takenaka, S.,
Diekmann, F., Eickelberg, O., Königshoff, M., Campistol, J.M.: Wnt pathway activation in long term
remnant rat model. Biomed Res. Int. 2014:324713 (2014)
Cao, Y., Jacobsen, N.R., Danielsen, P.H., Lenz, A.-G., Stöger, T., Loft, S., Wallin, H., Roursgaard, M.,
-/Mikkelsen, L., Møller, P.°: Vascular effects of multiwalled carbon nanotubes in dyslipidemic ApoE mice and
cultured endothelial cells. Toxicol. Sci. 138, 104-116 (2014)
Endes, C.°, Schmid, O., Kinnear, C., Mueller, S., Camarero-Espinosa, S., Vanhecke, D., Foster, E.J.,
Petri-Fink, A., Rothen-Rutishauser, B.M., Weder, C., Clift, M.J.D.: An in vitro testing strategy towards
mimicking the inhalation of high aspect ratio nanoparticles. Part. Fibre Toxicol. 11:40 (2014)
Gregor, M.#, Osmanagic-Myers, S.#, Burgstaller, G., Wolfram, M., Fischer, I., Walko, G., Resch, G.P., Jörgl,
A., Herrmann, H., Wiche, G.°: Mechanosensing through focal adhesion-anchored intermediate filaments.
FASEB J. 28, 715-729 (2014)
Haberl, N.°, Hirn, S., Wenk, A., Diendorf, J., Epple, M., Johnston, B.D., Krombach, F., Kreyling, W.G.,
Schleh, C.: Cytotoxic and proinflammatory effects of PVP-coated silver nanoparticles after intratracheal
instillation in rats. Beilstein J. Nanotechnol. 4, 933-940 (2013)
Hofer, T.P.°, Frankenberger, M., Heimbeck, I., Burggraf, D., Wjst, M., Wright, A.K.A., Kerscher, M.,
Nährig, S., Huber, R., Fischer, R., Ziegler-Heitbrock, L.: Decreased expression of HLA-DQ and HLA-DR on
cells of the monocytic lineage in cystic fibrosis. J. Mol. Med. 92, 1293-1304 (2014)
page 181 of 247
2015-11-23
#
joint first authors
#
#
John-Schuster, G. , Hager, K. , Conlon, T.M., Irmler, M., Beckers, J., Eickelberg, O., Yildirim, A.Ö.°:
2014]
PLoS ONE 9:e104568 (2014)
Kreyling, W.G.°, Fertsch-Gapp, S., Schäffler, M., Johnston, B.D., Haberl, N., Pfeiffer, C., Diendorf, J.,
Schleh, C., Hirn, S., Semmler-Behnke, M., Epple, M., Parak, W.J.: In vitro and in vivo interactions of
selected nanoparticles with rodent serum proteins and their consequences in biokinetics. Beilstein J.
Nanotechnol. 5, 1699-1711 (2014)
Kreyling, W.G.°, Hirn, S., Möller, W., Schleh, C., Wenk, A., Celik, G., Lipka, J., Schäffler, M., Haberl, N.,
Johnston, B.D., Sperling, R.A., Schmid, G., Simon, U., Parak, W.J., Semmler-Behnke, M.: Air-blood barrier
translocation of tracheally instilled gold nanoparticles inversely depends on particle size. ACS Nano 8,
222-233 (2014)
Lenz, A.-G., Stöger, T., Cei, D., Schmidmeir, M., Pfister, N., Burgstaller, G., Lentner, B., Eickelberg, O.,
Meiners, S., Schmid, O.°: Efficient bioactive delivery of aerosolized drugs to human pulmonary epithelial
cells cultured at air-liquid interface conditions. Am. J. Respir. Cell Mol. Biol. 51, 526-535 (2014)
Lomnicki, S., Gullett, B., Stöger, T., Kennedy, I.R., Díaz, J., Dugas, T.R., Varner, K., Carlin, D.J., Dellinger,
B., Cormier, S.A.°: Combustion by-products and their health effects - combustion engineering and global
health in the 21st century: Issues and challenges. Int. J. Toxicol. 33, 3-13 (2014)
page 182 of 247
2015-11-23
#
joint first authors
#
#
#
#
#
#
#
#
#
Genet. 46, 669-677 (2014)
Möller, W.°, Schuschnig, U., Bartenstein, P., Meyer, G., Häussinger, K., Schmid, O., Becker, S.: Drug
delivery to paranasal sinuses using pulsating aerosols. J. Aerosol Med. Pulm. Drug Deliv. 27, 255-263
(2014)
online 2014]
Schäffler, M., Sousa, F., Wenk, A., Sitia, L., Hirn, S., Schleh, C., Haberl, N., Violatto, M., Canovi, M.,
Andreozzi, P., Salmona, M., Bigini, P., Kreyling, W.G.°, Krol, S.°: Blood protein coating of gold nanoparticles
as potential tool for organ targeting. Biomaterials 35, 3455-3466 (2014)
page 183 of 247
2015-11-23
#
joint first authors
Schamberger, A.C., Mise, N., Meiners, S., Eickelberg, O.°: Epigenetic mechanisms in COPD: Implications
for pathogenesis and drug discovery. Expert Opin. Drug Discov. 9, 609-628 (2014)
Semmler-Behnke, M., Lipka, J., Wenk, A., Hirn, S., Schäffler, M., Tian, F., Schmid, G., Oberdörster, G.,
Kreyling, W.G.°: Size dependent translocation and fetal accumulation of gold nanoparticles from maternal
blood in the rat. Part. Fibre Toxicol. 11:33 (2014)
Upadhyay, S.°, Stöger, T., George, L., Schladweiler, M.C., Kodavanti, U.P., Ganguly, K., Schulz, H.°:
Ultrafine carbon particle mediated cardiovascular impairment of aged spontaneously hypertensive rats. Part.
Fibre Toxicol. 11:36 (2014)
Velroyen, A., Bech, M., Zanette, I., Schwarz, J., Rack, A., Tympner, C., Herrler, T., Staab-Weijnitz, C.A.,
Braunagel, M., Reiser, M., Bamberg, F., Pfeiffer, F., Notohamiprodjo, M.°: X-ray phase-contrast tomography
of renal ischemia-reperfusion damage. PLoS ONE 9:e109562 (2014)
Yaroshenko, A., Meinel, F.G., Hellbach, K., Bech, M., Velroyen, A., Müller, M., Bamberg, F., Nikolaou, K.,
Reiser, M.F., Yildirim, A.Ö., Eickelberg, O., Pfeiffer, F.: Small-animal dark-field radiography for pulmonary
emphysema evaluation. Proc. SPIE 9033:90331M (2014)
page 184 of 247
2015-11-23
#
joint first authors
Institute of Molecular Immunology
Albert, M.H., Mannert, J., Fleischmann, K.K., Schiemann, M., Pagel, P., Schmid, I., Magg, T.°: MiRNome
and transcriptome aided pathway analysis in human regulatory T cells. Genes Immun. 15, 303-312 (2014)
Arndt, B.°, Witkowski, L., Ellwart, J.W., Seissler, J.: CD8+ CD122+ PD-1- effector cells promote the
#
#
Avci, D. , Fuchs, S. , Schrul, B., Fukumori, A., Breker, M., Frumkin, I., Chen, C.Y., Biniossek, M.L.,
Kremmer, E., Schilling, O., Steiner, H., Schuldiner, M.°, Lemberg, M.K.°: The yeast ER-intramembrane
protease Ypf1 refines nutrient sensing by regulating transporter abundance. Mol. Cell 56, 630-640 (2014)
Beaufort, N.#, Scharrer, E.#, Kremmer, E., Lux, V., Ehrmann, M., Huber, R.°, Houlden, H., Werring, D.,
Haffner, C.°, Dichgans, M.°: Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β
binding protein 1 and facilitates TGF-β signaling. Proc. Natl. Acad. Sci. U.S.A. 111, 16496-16501 (2014)
#
#
Bohne, F. , Londoño, M.C. , Benítez, C., Miquel, R., Martínez-Llordella, M., Russo, C., Ortiz, C.,
Bonaccorsi-Riani, E., Brander, C., Bauer, T., Protzer, U., Jaeckel, E., Taubert, R., Forns, X., Navasa, M.,
Berenguer, M., Rimola, A., Lozano, J.J., Sánchez-Fueyo, A.°: HCV-induced immune responses influence the
development of operational tolerance after liver transplantation in humans. Sci. Transl. Med. 6:242ra81
(2014)
Borgstahl, G.E.°, Brader, K., Mosel, A., Liu, S., Kremmer, E., Goettsch, K.A., Kolar, C., Nasheuer, H.P.,
Oakley, G.G.: Interplay of DNA damage and cell cycle signaling at the level of human replication protein A.
DNA Repair 21, 12-23 (2014)
Chiozzini, C., Collacchi, B., Nappi, F., Bauer, T., Arenaccio, C., Tripiciano, A., Longo, O., Ensoli, F., Cafaro,
+
A., Ensoli, B., Federico, M.°: Surface-bound Tat inhibits antigen-specific CD8 T-cell activation in an
integrin-dependent manner. Aids 28, 2189-2200 (2014)
Doppler, S.A.°, Werner, A., Barz, M., Lahm, H., Deutsch, M.A., Dreßen, M., Schiemann, M., Voss, B.,
Gregoire, S., Kuppusamy, R., Wu, S.M., Lange, R., Krane, M.: Myeloid zinc finger 1 (Mzf1) differentially
modulates murine cardiogenesis by interacting with an Nkx2.5 cardiac enhancer. PLoS ONE 9:e113775
(2014)
Edelmann, S.L., Heissmeyer, V.°: Tfh cell differentiation: Missing stat3 uncovers interferons' interference.
Immunity 40, 307-330 (2014)
Götzl, J.K., Mori, K., Damme, M., Fellerer, K., Tahirovic, S., Kleinberger, G., Janssens, J., van der Zee, J.,
Lang, C.M., Kremmer, E., Martin, J.J., Engelborghs, S., Kretzschmar, H.A., Arzberger, T., van Broeckhoven,
C., Haass, C.°, Capell, A.°: Common pathobiochemical hallmarks of progranulin-associated frontotemporal
lobar degeneration and neuronal ceroid lipofuscinosis. Acta Neuropathol. 127, 845-860 (2014)
page 185 of 247
2015-11-23
#
joint first authors
#
#
Graef, P. , Buchholz, V.R. , Stemberger, C., Flossdorf, M., Henkel, L., Schiemann, M., Drexler, I., Höfer, T.,
Riddell, S.R., Busch, D.H.°: Serial transfer of single-cell-derived immunocompetence reveals stemness of
+
CD8 central memory T cells. Immunity 41, 116-126 (2014)
Höfig, K.P.°, Heissmeyer, V.°: Degradation of oligouridylated histone mRNAs: See UUUUU and goodbye.
Wiley Interdiscip. Rev. RNA 5, 577-589 (2014)
Hömberg, N., Adam, C., Riedel, T., Brenner, C., Flatley, A., Röcken, M., Mocikat, R.°: CD40-independent
NK-cell help promotes dendritic cell vaccine-induced T-cell immunity against endogenous B-cell lymphoma.
Int. J. Cancer 135, 2825-2833 (2014)
Huang, Y., Wolf, S., Beck, B., Köhler, L.-M., Khoury, K., Popowicz, G.M., Goda, S.K., Subklewe, M.,
Twarda, A., Holak, T.A., Dömling, A.°: Discovery of highly potent p53-MDM2 antagonists and structural basis
for anti-acute myeloid leukemia activities. ACS Chem. Biol. 9, 802-811 (2014)
Hubmann, M.°, Köhnke, T., Hoster, E., Schneider, S., Dufour, A., Zellmeier, E., Fiegl, M., Braess, J.,
Bohlander, S.K., Subklewe, M., Sauerland, M.C., Berdel, W.E., Büchner, T., Wörmann, B., Hiddemann, W.,
Spiekermann, K.: Molecular response assessment by quantitativerael-time polymerase chain reaction after
induction therapy in NPM1-mutated patients identifies patients at high risk for relapse. Haematologica 99,
1317-1325 (2014)
Janke, H.°, Pastore, F., Schumacher, D., Herold, T., Hopfner, K.P., Schneider, S., Berdel, W.E., Büchner,
T., Woermann, B.J., Subklewe, M., Bohlander, S.K., Hiddemann, W., Spiekermann, K., Polzer, H.:
Activating FLT3 mutants show distinct gain-of-function phenotypes in vitro and a characteristic signaling
pathway profile associated with prognosis in acute myeloid leukemia. PLoS ONE 9:e89560 (2014)
#
#
#
Jeltsch, K. , Hu, D. , Brenner, S. , Zöller, J., Heinz, G.A., Nagel, D., Vogel, K.U., Rehage, N., Warth,
S.C., Edelmann, S.L., Gloury, R., Martin, N., Lohs, C., Lech, M., Stehklein, J.E., Geerlof, A., Kremmer,
E., Weber, A., Anders, H.J., Schmitz, I., Schmidt-Supprian, M., Fu, M., Holtmann, H., Krappmann, D.,
Ruland, J., Kallies, A., Heikenwälder, M., Heissmeyer, V.°: Cleavage of roquin and regnase-1 by the
paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation. Nat.
Immunol. 15, 1079-1089 (2014)
systemic phenotypic analysis of Slc12a1 I299F mutant mice. J. Biomed. Sci. 21:68 (2014)
Klar, R., Schober, S., Rami, M., Mall, S., Merl, J., Hauck, S.M., Ueffing, M., Admon, A., Slotta-Huspenina,
J., Schwaiger, M., Stevanovic, S., Oostendorp, R.A., Busch, D.H., Peschel, C., Krackhardt, A.M.°:
Therapeutic targeting of naturally presented myeloperoxidase-derived HLA peptide ligands in myeloid
leukemia cells by TCR-transgenic T cells. Leukemia 28, 2355-2366 (2014)
page 186 of 247
2015-11-23
#
joint first authors
Kobold, S., Steffen, J., Chaloupka, M., Grassmann, S., Henkel, J., Castoldi, R., Zeng, Y., Chmielewski, M.,
Schmollinger, J.C., Schnurr, M., Rothenfußer, S., Schendel, D.J., Abken, H., Sustmann, C., Niederfellner,
G., Klein, C., Bourquin, C., Endres, S.°: Selective bispecific T cell recruiting antibody and antitumor activity of
adoptive T cell transfer. J. Natl. Cancer Inst. 107:dju364 (2015) [published online 2014]
PLoS ONE 9:e104568 (2014)
Lichtenegger, F.S., Lorenz, R., Gellhaus, K., Hiddemann, W., Beck, B., Subklewe, M.°: Impaired NK cells
and increased T regulatory cell numbers during cytotoxic maintenance therapy in AML. Leuk. Res. 38,
964-969 (2014)
Lichtenegger, F.S.°, Schnorfeil, F.M., Emmerig, K., Schlueter, M., Neitz, J.S., Draenert, R., Hiddemann,
W., Subklewe, M.: Pseudo-exhaustion of T cells in relapsed AML. Haematologica 99, 288-289 (2014)
Limmer, S., Hahn, J., Schmidt, R., Wachholz, K., Zengerle, A., Lechner, K., Eibl, H., Issels, R.D.,
Hossann, M.°, Lindner, L.H.: Gemcitabine treatment of rat soft tissue sarcoma with
phosphatidyldiglycerol-based thermosensitive liposomes. Pharm. Res. 31, 2276-2286 (2014)
Luteijn, R.D., Hoelen, H., Kruse, E., van Leeuwen, W.F., Grootens, J., Horst, D., Koorengevel, M., Drijfhout,
J.W., Kremmer, E., Früh, K., Neefjes, J.J., Killian, A., Lebbink, R.J., Ressing, M.E., Wiertz, E.J.°: Cowpox
virus protein CPXV012 eludes CTLs by blocking ATP binding to TAP. J. Immunol. 193, 1578-1589 (2014)
Ma, H.C., Liu, Y., Wang, C., Strauss, M., Rehage, N., Chen, Y.H., Altan-Bonnet, N., Hogle, J., Wimmer, E.,
Mueller, S., Paul, A.V., Jiang, P.°: An interaction between glutathione and the capsid is required for the
morphogenesis of c-cluster enteroviruses. PLoS Pathog. 10:e1004052 (2014)
May, S., Hornburg, D., Schludi, M.H., Arzberger, T., Rentzsch, K., Schwenk, B.M., Grässer, F.A., Mori, K.,
Kremmer, E., Banzhaf-Strathmann, J., Mann, M., Meissner, F., Edbauer, D.°: C9orf72
FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration.
Acta Neuropathol. 128, 485-503 (2014)
page 187 of 247
2015-11-23
#
joint first authors
#
#
#
Mohanta, S.K. , Yin, C. , Peng, L., Srikakulapu, P., Bontha, V., Hu, D., Weih, F., Weber, C., Gerdes, N. ,
#
Habenicht, A.J.R. °: Artery tertiary lymphoid organs contribute to innate and adaptive immune responses in
advanced mouse atherosclerosis. Circ. Res. 114, 1772-1787 (2014)
Naujoks, M.#, Weiß, J.#, Riedel, T., Hömberg, N., Przewoznik, M., Nößner, E., Röcken, M., Mocikat, R.°:
Alterations of costimulatory molecules and instructive cytokines expressed by dendritic cells in the
microenvironment of an endogenous mouse lymphoma. Cancer Immunol. Immunother. 63, 491-499 (2014)
Niess, H., Camaj, P., Renner, A., Ischenko, I., Zhao, Y., Krebs, S., Mysliwietz, J., Jäckel, C., Nelson, P.J.,
Blum, H., Jauch, K.W., Ellwart, J.W., Bruns, C.J.°: Side population cells of pancreatic cancer show
characteristics of cancer stem cells responsible for resistance and metastasis. Target. Oncol. 10, 215-227
Odendahl, M.#, Grigoleit, G.U.#, Bönig, H., Neuenhahn, M., Albrecht, J., Anderl, F., Germeroth, L., Schmitz,
M., Bornhäuser, M., Einsele, H., Seifried, E., Busch, D.H., Tonn, T.°: Clinical-scale isolation of 'minimally
manipulated' cytomegalovirus-specific donor lymphocytes for the treatment of refractory cytomegalovirus
disease. Cytotherapy 16, 1245-1256 (2014)
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Pichlo, M. , Bungert-Plümke, S. , Weyand, I., Seifert, R., Bönigk, W., Strünker, T., Kashikar, N.D., Goodwin,
N., Müller, A., Pelzer, P., Van, Q., Enderlein, J., Klemm, C., Krause, E., Trötschel, C., Poetsch, A.,
Kremmer, E., Kaupp, U.B.°: High density and ligand affinity confer ultrasensitive signal detection by a
guanylyl cyclase chemoreceptor. J. Cell Biol. 206, 541-557 (2014)
Pinto, S., Sommermeyer, D., Michel, C., Wilde, S., Schendel, D.J., Uckert, W., Blankenstein, T., Kyewski,
B.°: Misinitiation of intrathymic MART-1 transcription and biased TCR usage explain the high frequency of
MART-1-specific T cells. Eur. J. Immunol. 44, 2811-2821 (2014)
Prinz, P.U., Mendler, A.N., Brech, D., Masouris, I., Oberneder, R., Nößner, E.°: NK-cell dysfunction in
human renal carcinoma reveals diacylglycerol kinase as key regulator and target for therapeutic intervention.
Int. J. Cancer 135, 1832-1841 (2014)
Rabenstein, H.#, Behrendt, A.C.#, Ellwart, J.W., Naumann, R., Horsch, M., Beckers, J., Obst, R.°:
Differential kinetics of antigen dependency of CD4+ and CD8+ T cells. J. Immunol. 192, 3507-3517 (2014)
Ranjan, P.°, Singh, N., Kumar, A., Neerincx, A., Kremmer, E., Cao, W., Davis, W.G., Katz, J.M., Gangappa,
S., Lin, R., Kufer, T.A.°, Sambhara, S.: NLRC5 interacts with RIG-I to induce a robust antiviral response
against influenza virus infection. Eur. J. Immunol. 45, 758-772 (2015) [published online 2014]
Rascher, D., Geerlof, A., Kremmer, E., Krämer, P., Michael, S., Hartmann, A., Rieger, M.°: Total Internal
Reflection (TIRF)-based quantification of procalcitonin for sepsis diagnosis - a point-of-care testing
application. Biosens. Bioelectron. 59, 251-258 (2014)
Rieger, M.°, Kochleus, C., Teschner, D., Rascher, D., Barton, A.K., Geerlof, A., Kremmer, E., Schmid,
M., Hartmann, A., Gehlen, H.: A new ELISA for the quantification of equine procalcitonin in plasma as
potential inflammation biomarker in horses. Anal. Bioanal. Chem. 406, 5507-5512 (2014)
page 188 of 247
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Ritter, M., Straubinger, K., Schmidt, S., Busch, D.H., Hagner, S., Garn, H., da Costa, C.P., Layland, L.E.°:
Functional relevance of NLRP3 inflammasome-mediated interleukin (IL)-1 beta during acute allergic airway
inflammation. Clin. Exp. Immunol. 178, 212-223 (2014)
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Schlundt, A. , Heinz, G.A. , Janowski, R. , Geerlof, A., Stehle, R., Heissmeyer, V.°, Niessing, D.°,
Sattler, M.°: Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Nat. Struct. Mol. Biol. 21, 671-678 (2014)
Stemberger, C., Graef, P., Odendahl, M., Albrecht, J., Doessinger, G., Anderl, F., Buchholz, V.R.,
Gasteiger, G., Schiemann, M., Grigoleit, G.U., Schuster, F.R., Borkhardt, A., Versluys, B., Tonn, T.,
Seifried, E., Einsele, H., Germeroth, L., Busch, D.H., Neuenhahn, M.°: Lowest numbers of primary CD8+ T
cells can reconstitute protective immunity upon adoptive immunotherapy. Blood 124, 628-637 (2014)
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Subklewe, M., Geiger, C.°, Lichtenegger, F.S., Javorovic, M., Kvalheim, G., Schendel, D.J., Bigalke, I.:
New generation dendritic cell vaccine for immunotherapy of acute myeloid leukemia. Cancer Immunol.
Immunother. 63, 1093-1103 (2014)
Ullius, A., Luscher-Firzlaff, J., Costa, I.G., Walsemann, G., Forst, A.H., Gusmao, E.G., Kapelle, K., Kleine,
H., Kremmer, E., Vervoorts, J.°, Lüscher, B.°: The interaction of MYC with the trithorax protein ASH2L
promotes gene transcription by regulating H3K27 modification. Nucleic Acids Res. 42, 6901-6920 (2014)
van de Weijer, M.L., Bassik, M.C., Luteijn, R.D., Voorburg, C.M., Lohuis, M.A., Kremmer, E., Hoeben, R.C.,
Leproust, E.M., Chen, S., Hoelen, H., Ressing, M.E., Patena, W., Weissman, J.S., McManus, M.T.°, Wiertz,
E.J.°, Lebbink, R.J.°: A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in
ER-associated protein degradation. Nat. Commun. 5:3832 (2014)
van Gent, M., Braem, S.G., de Jong, A., Delagic, N., Peeters, J.G., Boer, I.G., Moynagh, P.N., Kremmer, E.,
Wiertz, E.J., Ovaa, H., Griffin, B.D., Ressing, M.E.°: Epstein-Barr virus large tegument protein BPLF1
contributes to innate immune evasion through interference with toll-like receptor signaling. PLoS Pathog.
10:e1003960 (2014)
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Vogt, V. , Walcher, T. , Ansprenger, C., Braeu, M., Kroell, T., Kraemer, D.M., Köhne, C.H., Hausmann, A.,
Buhmann, R., Tischer, J., Schmetzer, H.M.: Profiles of activation, differentiation-markers, or β-integrins on
T cells contribute to predict T cells' antileukemic responses after stimulation with leukemia-derived dendritic
cells. J. Immunother. 37, 331-347 (2014)
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Institute of Molecular Toxicology and Pharmacology
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Dolga, A.M. °, de Andrade, A. , Meissner, L., Knaus, H.G., Höllerhage, M., Christophersen, P., Zischka, H.,
Plesnila, N., Höglinger, G.U., Culmsee, C.: Subcellular expression and neuroprotective effects of SK
channels in human dopaminergic neurons. Cell Death Dis. 5:e999 (2014)
Eisenhofer, S.°, Efendiyev, M.A., Otani, M., Schulz, S., Zischka, H.: On the ODE-PDE coupling model of
the mitochondrial swelling process. Discrete Contin. Dyn. Syst.-Ser. B 20, 1031-1057 (2015) [published
online 2014]
Foerster, F., Braig, S., Moser, C., Kubisch, R., Busse, J., Wagner, E., Schmoeckel, E., Mayr, D., Schmitt, S.,
Huettel, S., Zischka, H., Mueller, R., Vollmar, A.M.°: Targeting the actin cytoskeleton: Selective antitumor
action via trapping PKCɛ. Cell Death Dis. 5:e1398 (2014)
Gul, S., Hadian, K.°: Protein-protein interaction modulator drug discovery: Past efforts and future
opportunities using a rich source of low- and high-throughput screening assays. Expert Opin. Drug Discov. 9,
1393-1404 (2014)
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Heim, A. , Grimm, C. , Müller, U., Häußler, S., Mackeen, M.M., Merl, J., Hauck, S.M., Kessler, B.M.,
Schofield, C.J., Wolf, A.°, Böttger, A.°: Jumonji domain containing protein 6 (Jmjd6) modulates splicing and
specifically interacts with arginine-serine-rich (RS) domains of SR- and SR-like proteins. Nucleic Acids Res.
42, 7833-7850 (2014)
Jeltsch, K.#, Hu, D.#, Brenner, S.#, Zöller, J., Heinz, G.A., Nagel, D., Vogel, K.U., Rehage, N., Warth,
Immunol. 15, 1079-1089 (2014)
Loenarz, C., Sekirnik, R., Thalhammer, A., Ge, W., Spivakovsky, E., Mackeen, M.M., McDonough, M.A.,
Cockman, M.E., Kessler, B.M., Ratcliffe, P.J., Wolf, A., Schofield, C.J.°: Hydroxylation of the eukaryotic
ribosomal decoding center affects translational accuracy. Proc. Natl. Acad. Sci. U.S.A. 111, 4019-4024
(2014)
Mc Guire, C., Elton, L., Wieghofer, P., Staal, J., Voet, S., Demeyer, A., Nagel, D., Krappmann, D., Prinz, M.,
Beyaert, R.°, van Loo, G.°: Pharmacological inhibition of MALT1 protease activity protects mice in a mouse
model of multiple sclerosis. J. Neuroinflamm. 11:124 (2014)
Nagel, D., Vincendeau, M., Eitelhuber, A.C., Krappmann, D.°: Mechanisms and consequences of
constitutive NF-κB activation in B-cell lymphoid malignancies. Oncogene 33, 5655-5665 (2014)
Schimmack, G., Eitelhuber, A.C., Vincendeau, M., Demski, K., Shinohara, H., Kurosaki, T., Krappmann,
D.°: AIP augments CARMA1-BCL10-MALT1 complex formation to facilitate NF-kappa B signaling upon T cell
activation. Cell Commun. Signal. 12:49 (2014)
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Institute of Molecular Toxicology and Pharmacology
Schmitt, S., Schulz, S., Schropp, E.-M., Eberhagen, C., Simmons, A., Beisker, W., Aichler, M., Zischka,
H.°: Why to compare absolute numbers of mitochondria. Mitochondrion 19, 113-123 (2014)
Schorpp, K.K.#, Rothenaigner, I.#, Salmina, E., Reinshagen, J., Low, T., Brenke, J.K., Gopalakrishnan, J.,
Tetko, I.V., Gul, S., Hadian, K.°: Identification of small-molecule frequent hitters from AlphaScreen
high-throughput screens. J. Biomol. Screen. 19, 715-726 (2013)
Schorpp, K.K.°, Hadian, K.°: Small molecule screening at Helmholtz Zentrum München - from biology to
molecules. Comb. Chem. High Throughput Screen. 7, 266-271 (2014)
9:e107069 (2014)
Singleton, R.S., Liu-Yi, P., Formenti, F., Ge, W., Sekirnik, R., Fischer, R., Adam, J., Pollard, P.J., Wolf, A.,
Thalhammer, A., Loenarz, C., Flashman, E., Yamamoto, A., Coleman, M.L., Kessler, B.M., Wappner, P.,
Schofield, C.J., Ratcliffe, P.J.°, Cockman, M.E.°: OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is
involved in translation control and stress granule formation. Proc. Natl. Acad. Sci. U.S.A. 111, 4031-4036
(2014)
Takaku, Y.#, Hwang, J.S.#, Wolf, A.#, Böttger, A., Shimizu, H., David, C.N., Gojobori, T.°: Innexin gap
junctions in nerve cells coordinate spontaneous contractile behavior in Hydra polyps. Sci. Rep. 4:3573
(2014)
Tassara, M., Döhner, K., Brossart, P., Held, G., Götze, K.S., Horst, H.A., Ringhoffer, M., Köhne, C.H.,
Kremers, S., Raghavachar, A.N., Wulf, G.G., Kirchen, H.G., Nachbaur, D.M., Derigs, H.G., Wattad, M.,
Koller, E.A., Brugger, W., Matzdorff, A.C., Greil, R.F., Heil, G., Paschka, P., Gaidzik, V.I., Göttlicher, M.,
Döhner, H., Schlenk, R.F.°: Valproic acid in combination with all-trans retinoic acid and intensive therapy for
acute myeloid leukemia in older patients. Blood 123, 4027-4036 (2014)
Vierling, C., Baumgartner, C.M., Bollerhey, M., Erhardt, W.D., Stampfl, A., Vierling, W.: The vasodilating
effect of a Hintonia latiflora extract with antidiabetic action. Phytomedicine 21, 1582-1586 (2014)
+
Zischka, H.°, Lichtmannegger, J.: Pathological mitochondrial copper overload in livers of Wilson's disease
patients and related animal models. Ann. NY Acad. Sci. 1315, 6-15 (2014)
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Institute of Pathology
Aichler, M., Motschmann, M., Jütting, U., Luber, B., Becker, K., Ott, K., Lordick, F., Langer, R., Feith, M.,
Siewert, J.R., Walch, A.K.°: Epidermal Growth Factor Receptor (EGFR) is an independent adverse
prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant
chemotherapy. Oncotarget 5, 6620-6632 (2014)
Aichler, M., Luber, B., Lordick, F., Walch, A.K.°: Proteomic and metabolic prediction of response to therapy
in gastric cancer. World J. Gastroenterol. 20, 13648-13657 (2014)
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Arabi, L. , Gsponer, J.R. , Smida, J., Nathrath, M., Perrina, V., Jundt, G., Ruiz, C., Quagliata, L., Baumhoer,
D.°: Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma - reasons and
consequences. Genes Cancer 5, 56-63 (2014)
Avitzur, Y.#, Guo, C.#, Mastropaolo, L.A.#, Bahrami, E., Chen, H., Zhao, Z., Elkadri, A., Dhillon, S., Murchie,
R., Fattouh, R., Huynh, H., Walker, J.L., Wales, P.W., Cutz, E., Kakuta, Y., Dudley, J., Kammermeier, J.,
Powrie, F., Shah, N., Walz, C., Nathrath, M., Kotlarz, D., Puchaka, J., Krieger, J., Racek, T., Kirchner, T.,
Walters, T.D., Brumell, J.H., Griffiths, A.M., Rezaei, N., Rashtian, P., Najafi, M., Monajemzadeh, M., Pelsue,
S., McGovern, D.P., Uhlig, H.H., Schadt, E., Klein, C., Snapper, S.B., Muise, A.M.°: Mutations in
tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease.
Gastroenterology 146, 1028-1039 (2014)
#
Balluff, B. , Frese, C.K., Maier, S.K., Schöne, C., Kuster, B., Schmitt, M., Aubele, M., Höfler, H., Deelder,
#
A.M., Heck, A.J., Hogendoorn, P.C.W., Morreau, J., Altelaar, A.F., Walch, A.K.°, McDonnell, L.A. °: De novo
discovery of phenotypic intra-tumor heterogeneity using imaging mass spectrometry. J. Pathol. 235, 3-13
(2014)
Baumgart, A.#, Mazur, P.K.#, Anton, M., Rudelius, M., Schwamborn, K., Feuchtinger, A., Behnke, K.,
Walch, A.K., Braren, R., Peschel, C., Duyster, J., Siveke, J.T.°, Dechow, T.: Opposing role of Notch1 and
Notch2 in a KrasG12D-driven murine non-small cell lung cancer model. Oncogene 34, 578–588 (2015)
Baumgart, S., Chen, N., Siveke, J.T., König, A.O., Zhang, J., Singh, S.K., Wolf, E., Bartkuhn, M., Esposito,
I., Heßmann, E., Reinecke, J., Nikorowitsch, J., Brunner, M., Singh, G.P., Fernández-Zapico, M.E., Smyrk,
T.C., Bamlet, W.R., Eilers, M., Neeße, A., Gress, T.M., Billadeau, D.D., Tuveson, D.A., Urrutia, R.A.°,
Ellenrieder, V.: Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer
G12D
. Cancer Discov. 4, 688-701 (2014)
initiation by Kras
Berchtold, S., Grünwald, B., Krüger, A., Reithmeier, A., Hähl, T., Cheng, T., Feuchtinger, A., Born, D.,
Erkan, M., Kleeff, J., Esposito, I.°: Collagen type V promotes the malignant phenotype of pancreatic ductal
adenocarcinoma. Cancer Lett. 356, 721-732 (2015) [published online 2014]
Bézière, N.°, von Schacky, C., Kosanke, Y., Kimm, M., Nunes, A., Licha, K., Aichler, M., Walch, A.K.,
Rummeny, E.J., Ntziachristos, V., Meier, R.: Optoacoustic imaging and staging of arthritic inflammation.
Arthritis Rheum. 66, 2071-2078 (2014)
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Boeckh-Behrens, T.°, Schubert, M.I., Forschler, A., Prothmann, S., Kreiser, K., Zimmer, C., Riegger, J.,
Bauer, J., Neff, F., Kehl, V., Pelisek, J., Schirmer, L., Mehr, M., Poppert, H.: The impact of histological clot
composition in embolic stroke. Clin. Neuroradiol., DOI: 10.1007/s00062-014-0347-x (2014)
Buck, A., Walch, A.K.°: In situ drug and metabolite analyzes in biological and clinical research by
MALDI MS imaging. Bioanalysis 6, 1241-1253 (2014)
Buck, A., Halbritter, S., Späth, C., Feuchtinger, A., Aichler, M., Zitzelsberger, H., Janssen, K.P., Walch,
A.K.°: Distribution and quantification of irinotecan and its active metabolite SN-38 in colon cancer murine
model systems using MALDI MSI. Anal. Bioanal. Chem. 407, 2107-2116 (2015) [published online 2014]
Dekker, T.J., Balluff, B.D., Jones, E.A., Schöne, C.D., Schmitt, M., Aubele, M., Kroep, J.R., Smit, V.T.,
Tollenaar, R.A., Mesker, W.E., Walch, A.K., McDonnell, L.A.°: Multicenter Matrix-Assisted Laser
Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) identifies proteomic differences in
breast-cancer-associated stroma. J. Proteome Res. 13, 4730-4738 (2014)
Ehninger, D.°, Neff, F., Xie, K.: Longevity, aging and rapamycin. Cell. Mol. Life Sci. 71, 4325-4346 (2014)
Ermolayev, V., Mohajerani, P., Ale, A., Sarantopoulos, A., Aichler, M., Kayser, G., Walch, A.K.,
Ntziachristos, V.°: Early recognition of lung cancer by integrin targeted imaging in K-ras mouse model. Int.
J. Cancer 137, 1107-1118 (2015) [published online 2014]
Ewald, F., Annemann, M., Pils, M.C., Plaza-Sirvent, C., Neff, F., Erck, C., Reinhold, D., Schmitz, I.°:
Constitutive expression of murine c-FLIPR causes autoimmunity in aged mice. Cell Death Dis. 5:e1168
(2014)
Falkenberg, N., Anastasov, N., Höfig, I., Bashkueva, K., Lindner, K., Höfler, H., Rosemann, M., Aubele,
M.°: Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast
cancer progression in vivo. Mol. Oncol. 9, 282-294 (2015) [published online 2014]
Feuchtinger, A.°, Stiehler, T., Jütting, U., Marjanovic, G., Luber, B., Langer, R., Walch, A.K.: Image
analysis of immunohistochemistry is superior to visual scoring as shown for patient outcome of esophageal
adenocarcinoma. Histochem. Cell Biol. 143, 1-9 (2014)
1180-1191 (2014)
cells. eLife 3:e03842 (2014)
page 194 of 247
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joint first authors
Gorzolka, K., Walch, A.K.°: MALDI mass spectrometry imaging of formalin-fixed paraffin-embedded tissues
in clinical research. Histol. Histopathol. 29, 1365-1376 (2014)
Graf, N., Li, Z., Herrmann, K., Weh, D., Aichler, M., Slawska, J., Walch, A.K., Peschel, C., Schwaiger, M.,
Buck, A.K., Dechow, T., Keller, U.°: Positron emission tomographic monitoring of dual
phosphatidylinositol-3-kinase and mTOR inhibition in anaplastic large cell lymphoma. OncoTargets Ther. 7,
789-798 (2014)
Heimesaat, M.M.°, Fischer, A., Plickert, R., Wiedemann, T., Loddenkemper, C., Göbel, U.B., Bereswill, S.,
Rieder, G.: Helicobacter pylori induced gastric immunopathology is associated with distinct microbiota
changes in the large intestines of long-term infected Mongolian gerbils. PLoS ONE 9:e100362 (2014)
Huber, K., Feuchtinger, A., Borgmann, D.M., Li, Z., Aichler, M., Hauck, S.M., Zitzelsberger, H.,
Schwaiger, M., Keller, U., Walch, A.K.°: A novel approach of MALDI drug imaging, immunohistochemistry,
and digital image analysis for drug distribution studies in tissues. Anal. Chem. 86, 10568-10575 (2014)
Icheva, V., Kayser, S., Wolff, D., Tuve, S., Kyzirakos, C., Bethge, W.A., Greil, J., Albert, M.H., Schwinger,
W., Nathrath, M., Schumm, M.A., Stevanovic, S., Handgretinger, R., Lang, P., Feuchtinger, T.°: Adoptive
transfer of Epstein-Barr Virus (EBV) nuclear antigen 1-specific T cells as treatment for EBV reactivation and
lymphoproliferative disorders after allogeneic stem-cell transplantation. J. Clin. Oncol. 31, 39-48 (2013)
Jin, S., Kim, J., Willert, T., Klein-Rodewald, T., Garcia-Dominguez, M., Mosqueira, M., Fink, R., Esposito,
I., Hofbauer, L.C., Charnay, P., Kieslinger, M.°: Ebf factors and MyoD cooperate to regulate muscle
relaxation via Atp2a1. Nat. Commun. 5:3793 (2014)
2014]
page 195 of 247
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Kempf, S.J., Casciati, A., Buratovic, S., Janik, D., von Toerne, C., Ueffing, M., Neff, F., Mörtl, S.,
Stenerlöw, B., Saran, A., Atkinson, M.J., Eriksson, P., Pazzaglia, S., Tapio, S.°: The cognitive defects of
neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and
neuroinflammation. Mol. Neurodegener. 9:57 (2014)
PLoS ONE 9:e104568 (2014)
Kucharska, J., del Río, P., Arango-González, B., Gorza, M., Feuchtinger, A., Hauck, S.M.°, Ueffing, M.:
Cyr61 activates retinal cells and prolongs photoreceptor survival in rd1 mouse model of retinitis pigmentosa.
J. Neurochem. 130, 227-240 (2014)
Lee, M.S., Lupp, A., Mendoza, N.M., Martin, N.M., Beschorner, R., Honegger, J., Schlegel, J., Shively, T.,
Pulz, E., Schulz, S., Roncaroli, F.°, Pellegata, N.S.°: SSTR3 is a putative target for the medical treatment of
gonadotroph adenomas of the pituitary. Endocr.-Relat. Cancer 22, 111-119 (2015) [published online 2014]
Longuini, V.C., Lourenco-Jr, D.M., Sekiya, T., Meirelles, O.D., Goncalves, T.D., Coutinho, F.L., Francisco,
G., Osaki, L.H., Chammas, R., Alves, V.A., Siqueira, S.A., Schlesinger, D., Naslavsky, M.S., Zatz, M.,
Duarte, Y.A., Lebrao, M.L., Gama, P., Lee, M.S., Molatore, S., Pereira, M.A., Jallad, R.S., Bronstein, M.D.,
Cunha Neto, M.B., Liberman, B., Fragoso, M.C., Toledo, S.P., Pellegata, N.S., Toledo, R.A.°: Association
between the p27 rs2066827 variant and tumor multiplicity in patients harboring MEN1 germline mutations.
Eur. J. Endocrinol. 171, 335-342 (2014)
Ly, A.°, Schöne, C., Becker, M., Rattke, J., Meding, S., Aichler, M., Suckau, D., Walch, A.K., Hauck, S.M.,
Ueffing, M.°: High-resolution MALDI mass spectrometric imaging of lipids in the mammalian retina.
Histochem. Cell Biol. 143, 453-462 (2015) [published online 2014]
Maier, S.K., Bashkueva, K., Rösli, C., Skerra, A., Kuster, B.°: PAS-cal: A repetitive peptide sequence
calibration standard for MALDI mass spectrometry. Proteomics 14, 2427-2431 (2014)
Malinowsky, K., Nitsche, U., Janssen, K.P., Bader, F.G., Späth, C., Drecoll, E., Keller, G., Höfler, H.,
Slotta-Huspenina, J., Becker, K.F.°: Activation of the PI3K/AKT pathway correlates with prognosis in stage II
colon cancer. Br. J. Cancer 110, 2081-2089 (2014)
page 196 of 247
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McDonnell, L.A.°, Römpp, A., Balluff, B.D., Heeren, R.M.A., Albar, J.P., Andrén, P.E., Corthals, G.L., Walch,
A.K., Stoeckli, M.: Discussion point: Reporting guidelines for mass spectrometry imaging. Anal. Bioanal.
Chem. 407, 2035-2045 (2015) [published online 2014]
Meier, R.°, Braren, R., Kosanke, Y., Bussemer, J., Neff, F., Wildgruber, M., Schwarzenböck, S., Frank, A.,
Haller, B., Hohlbaum, A.M., Schwaiger, M., Gille, H., Rummeny, E.J., Beer, A.J.°: Multimodality
multiparametric imaging of early tumor response to a novel antiangiogenic therapy based on anticalins. PLoS
ONE 9:e94972 (2014)
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Mengel, D. , Röskam, S. , Neff, F., Balakrishnan, K., Deuster, O., Gold, M., Oertel, W.H., Bacher, M., Bach,
J.P., Dodel, R.°: Naturally occurring autoantibodies interfere with β-amyloid metabolism and improve
cognition in a transgenic mouse model of Alzheimer's disease 24 h after single treatment. Transl. Psychiatry
3:e236 (2013)
Niedzielska, M., Bodendorfer, B., Münch, S., Eichner, A., Derigs, M., da Costa, O.P., Schweizer, A., Neff, F.,
Nitschke, L., Sparwasser, T., Keyse, S.M., Lang, R.°: Gene trap mice reveal an essential function of dual
specificity phosphatase Dusp16/MKP-7 in perinatal survival and regulation of Toll-Like Receptor
(TLR)-induced cytokine production. J. Biol. Chem. 289, 2112-2126 (2014)
Pardi, E., Mariotti, S., Pellegata, N.S., Benfini, K., Borsari, S., Saponaro, F., Torregrossa, L., Cappai, A.,
Satta, C., Mastinu, M., Marcocci, C., Cetani, F.°: Functional characterization of a CDKN1B mutation in a
Sardinian kindred with Multiple Endocrine Neoplasia type 4 (MEN4). Endocr. Connect. 4, 1-8 (2015)
Poos, K., Smida, J., Nathrath, M., Maugg, D., Baumhoer, D., Neumann, A., Korsching, E.°: Structuring
osteosarcoma knowledge: An osteosarcoma-gene association database based on literature mining and
manual annotation. Database (Oxford) 2014:bau042 (2014)
Schenck, T.L.°, Stewart, J., Lin, S., Aichler, M., Machens, H.G., Giunta, R.E.: Anatomical and
histomorphometric observations on the transfer of the anterior interosseous nerve to the deep branch of the
ulnar nerve. J. Hand Surg. Eur. 40, 591-596 (2015) [published online 2014]
Schmitt, S., Schulz, S., Schropp, E.-M., Eberhagen, C., Simmons, A., Beisker, W., Aichler, M., Zischka,
H.°: Why to compare absolute numbers of mitochondria. Mitochondrion 19, 113-123 (2014)
Sekiya, T., Bronstein, M.D., Benfini, K., Longuini, V.C., Jallad, R.S., Machado, M.C., Goncalves, T.D.,
Osaki, L.H., Higashi, L., Lima-Jr, J.V., Kater, C.E., Lee, M., Molatore, S., Francisco, G., Chammas, R.,
Naslavsky, M., Schlesinger, D., Gama, P., Duarte, Y.A., Lebrao, M.L., Zatz, M., Meirelles, O., Liberman, B.,
Fragoso, M.C., Toledo, S.P., Pellegata, N.S., Toledo, R.A.°: p27 variant and corticotropinoma susceptibility:
A genetic and in vitro study. Endocr.-Relat. Cancer 21, 395-404 (2014)
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Selmansberger, M., Feuchtinger, A., Zurnadzhy, L., Michna, A., Kaiser, J.C., Abend, M., Brenner, A.,
Bogdanova, T., Walch, A.K., Unger, K., Zitzelsberger, H., Heß, J.°: CLIP2 as radiation biomarker in
papillary thyroid carcinoma. Oncogene 34, 3917-3925 (2015) [published online 2014]
Slotta-Huspenina, J., Becker, K.F., Feith, M., Walch, A.K., Langer, R.°: Heat Shock Protein 90 (HSP90) and
Her2 in adenocarcinomas of the esophagus. Cancers 6, 1382-1393 (2014)
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Sun, N.#, Ly, A.#, Meding, S., Witting, M., Hauck, S.M., Ueffing, M., Schmitt-Kopplin, P., Aichler, M.,
Walch, A.K.°: High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass
spectrometry. Proteomics 14, 913-923 (2014)
2293-2303 (2014)
Weber, E.#, Finsterbusch, K.#, Lindquist, R., Nair, S., Lienenklaus, S., Gekara, N.O., Janik, D., Weiss, S.,
Kalinke, U., Overby, A.K., Kröger, A.: Type I interferon protects mice from fatal neurotropic infection with
Langat virus by systemic and local anti-viral response. J. Virol. 88, 12202-12212 (2014)
(2014)
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Institute of Radiation Biology
Bakshi, M.V., Azimzadeh, O., Barjaktarovic, Z., Kempf, S.J., Merl-Pham, J., Hauck, S.M., Buratovic, S.,
Eriksson, P., Atkinson, M.J., Tapio, S.°: Total body exposure to low-dose ionizing radiation induces
long-term alterations to the liver proteome of neonatally exposed mice. J. Proteome Res. 14, 366-373 (2015)
Falkenberg, N., Anastasov, N., Höfig, I., Bashkueva, K., Lindner, K., Höfler, H., Rosemann, M., Aubele,
M.°: Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast
cancer progression in vivo. Mol. Oncol. 9, 282-294 (2015) [published online 2014]
González, F.°, Kirwan, J.P., Rote, N.S., Minium, J., O'Leary, V.B.: Glucose and lipopolysaccharide regulate
proatherogenic cytokine release from mononuclear cells in polycystic ovary syndrome. J. Reprod. Immunol.
103, 38-44 (2014)
Höfig, I., Barth, S., Salomon, M., Jagusch, V., Atkinson, M.J., Anastasov, N., Thirion, C.°: Systematic
improvement of lentivirus transduction protocols by antibody fragments fused to VSV-G as envelope
glycoprotein. Biomaterials 35, 4204-4212 (2014)
Kempf, S.J., Buratovic, S., von Toerne, C., Mörtl, S., Stenerlöw, B., Hauck, S.M., Atkinson, M.J.,
Eriksson, P., Tapio, S.°: Ionising radiation immediately impairs synaptic plasticity-associated cytoskeletal
signalling pathways in HT22 cells and in mouse brain: An in vitro/in vivo comparison study. PLoS ONE
9:e110464 (2014)
Kraemer, A., Chen, I.P., Henning, S., Faust, A., Volkmer, B., Atkinson, M.J., Mörtl, S., Greinert, R.°: UVA
and UVB irradiation differentially regulate microRNA expression in human primary keratinocytes. PLoS ONE
8:e83392 (2013)
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Institute of Radiation Biology
Kulka, U.°, Ainsbury, L., Atkinson, M.J., Barnard, S., Smith, R., Barquinero, J.F., Barrios, L., Bassinet, C.,
Beinke, C., Cucu, A., Darroudi, F., Fattibene, P., Bortolin, E., Monaca, S.D., Gil, O., Gregoire, E.,
Hadjidekova, V., Haghdoost, S., Hatzi, V., Hempel, W., Herranz, R., Jaworska, A., Lindholm, C., Lumniczky,
K., M'kacher, R., Mörtl, S., Montoro, A., Moquet, J., Moreno, M., Noditi, M., Ogbazghi, A., Oestreicher, U.,
Palitti, F., Pantelias, G., Popescu, I., Prieto, M.J., Roch-Lefevre, S., Roessler, U., Romm, H., Rothkamm, K.,
Sabatier, L., Sebastià, N., Sommer, S., Terzoudi, G., Testa, A., Thierens, H., Trompier, F., Turai, I.,
Vandevoorde, C., Vaz, P., Voisin, P., Vral, A., Ugletveit, F., Wieser, A., Woda, C., Wojcik, A.: Realising the
European network of biodosimetry: RENEB - status quo. Radiat. Prot. Dosim. 164, 42-45 (2015) [published
online 2014]
Litzenburger, U.M., Opitz, C.A.°, Sahm, F., Rauschenbach, K.J., Trump, S., Winter, M., Ott, M., Ochs, K.,
Lutz, C., Liu, X., Anastasov, N., Lehmann, I., Höfer, T., von Deimling, A., Wick, W., Platten, M.°: Constitutive
IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the
AHR. Oncotarget 5, 1038-1051 (2014)
Maroschik, B., Gürtler, A., Krämer, A., Rößler, U., Gomolka, M., Hornhardt, S., Mörtl, S., Friedl, A.A.°:
Radiation-induced alterations of histone post-translational modification levels in lymphoblastoid cell lines.
Radiat. Oncol. 9:15 (2014)
Ovsepian, S.V.°, Antyborzec, I., O'Leary, V.B., Zaborszky, L., Herms, J., Dolly, J.O.: Neurotrophin receptor
p75 mediates the uptake of the amyloid beta (A β) peptide, guiding it to lysosomes for degradation in basal
forebrain cholinergic neurons. Brain Struct. Funct. 219, 1527-1541 (2014)
Rombouts, C., Aerts, A.L.°, Quintens, R., Baselet, B., El-Saghire, H., Harms-Ringdahl, M., Haghdoost, S.,
Janssen, A., Michaux, A., Yentrapalli, R., Benotmane, M.A., van Oostveldt, P.M., Baatout, S.:
Transcriptomic profiling suggests a role for IGFBP5 in premature senescence of endothelial cells after
chronic low dose rate irradiation. Int. J. Radiat. Biol. 90, 560-574 (2014)
Sievert, W., Tapio, S., Breuninger, S., Gaipl, U., Andratschke, N., Trott, K.R., Multhoff, G.°: Adhesion
molecule expression and function of primary endothelial cells in benign and malignant tissues correlates with
proliferation. PLoS ONE 9:e91808 (2014)
Sriharshan, A., Azimzadeh, O., Caldwell, R.B., Tapio, S.°: Proteomic strategies: SILAC and 2D-DIGE powerful tool to investigate cellular alterations. Methods Mol. Biol. 1101, 369-392 (2014)
Sriharshan, A., Krämer, A., Atkinson, M.J., Mörtl, S., Tapio, S.°: Radiation-induced crosstalk between
microRNAs and proteins of the endothelium: In silico analysis. J. Proteomics Bioinf. 7, 327-331 (2014)
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Institute of Radiation Protection
Ainsbury, E.A.°, Barnard, S., Barrios, L., Fattibene, P., de Gelder, V., Gregoire, E., Lindholm, C., Lloyd, D.,
Nergaard, I., Rothkamm, K., Romm, H., Scherthan, H., Thierens, H., Vandevoorde, C., Woda, C., Wojcik, A.:
Multibiodose radiation emergency triage categorization software. Health Phys. 107, 83-89 (2014)
Alloni, D.°, Cutaia, C., Mariotti, L., Friedland, W., Ottolenghi, A.: Modeling dose deposition and DNA
damage due to low-energy β- emitters. Radiat. Res. 182, 322-330 (2014)
Barros, S.°, Mares, V., Bedogni, R., Reginatto, M., Esposito, A., Goncalves, I.F., Vaz, P., Rühm, W.:
Comparison of unfolding codes for neutron spectrometry with Bonner spheres. Radiat. Prot. Dosim. 161,
46-52 (2014)
Bassinet, C.°, Woda, C., Bortolin, E., Della Monaca, S., Fattibene, P., Quattrini, M.C., Bulanek, B., Ekendahl,
D., Burbidge, C.I., Cauwels, V., Kouroukla, E.C., Geber-Bergstrand, T., Mrozik, A., Marczewska, B., Bilski,
P.X., Sholom, S.V., McKeever, S.W.S., Smith, R.W., Veronese, I., Galli, A., Panzeri, L., Martini, M.:
Retrospective radiation dosimetry using OSL of electronic components: Results of an inter-laboratory
comparison. Radiat. Meas. 71, 475-479 (2014)
Bergmeier, F.°, Volnhals, M., Wielunski, M., Rühm, W.: Simulation and calibration of an active neutron
dosemeter. Radiat. Prot. Dosim. 161, 126-129 (2014)
Brudecki, K.°, Li, W.B.°, Meisenberg, O., Tschiersch, J., Hoeschen, C., Oeh, U.: Age-dependent
inhalation doses to members of the public from indoor short-lived radon progeny. Radiat. Environ. Biophys.
53, 535-549 (2014)
Caresana, M.°, Denker, A., Esposito, A., Ferrarini, M., Golnik, N., Hohmann, E., Leuschner, A.,
Luszik-Bhadra, M., Manessi, G., Mayer, S., Ott, K., Röhrich, J., Silari, M., Trompier, F., Volnhals, M.,
Wielunski, M.: Intercomparison of radiation protection instrumentation in a pulsed neutron field. Nucl.
Instrum. Methods Phys. Res. Sect. A 737, 203-213 (2014)
Chege, M.W.°, Hashim, N.O., Merenga, A.S., Tschiersch, J.: Lead contamination of traditional hand-dug
wells in parts. Int. J. Phys. Sci. 8, 835-839 (2013)
Discher, M.°, Greiter, M.B., Woda, C.: Photon energy dependence and angular response of glass display
used in mobile phones for accident dosimetry. Radiat. Meas. 71, 471-474 (2014)
Discher, M.°, Woda, C.: Thermoluminescence emission spectrometry of glass display in mobile phones and
resulting evaluation of the dosimetric properties of a specific type of display glass. Radiat. Meas. 71, 480-484
(2014)
Fattibene, P.°, Trompier, F., Wieser, A., Brai, M., Ciesielski, B., de Angelis, C., Monaca, S.D., Garcia, T.,
Gustafsson, H., Hole, E.O., Juniewicz, M., Krefft, K., Longo, A., Leveque, P., Lund, E., Marrale, M., Michalec,
B., Mierzwińska, G., Rao, J.L., Romanyukha, A.A., Tuner, H.: EPR dosimetry intercomparison using smart
phone touch screen glass. Radiat. Environ. Biophys. 53, 311-320 (2014)
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Gierl, S. , Meisenberg, O. °, Haninger, T., Wielunski, M., Tschiersch, J.: An unattended device for
high-voltage sampling and passive measurement of thoron decay products Rev. Sci. Instruments 85:022103
(2014)
Gierl, S., Meisenberg, O.°, Feistenauer, P., Tschiersch, J.: Thoron and thoron progeny measurements in
German clay houses. Radiat. Prot. Dosim. 160, 160-163 (2014)
Hofmann, W.°, Winkler-Heil, R., Truta, L.A., Tschiersch, J.: Application of a Monte Carlo lung dosimetry
code to the inhalation of thoron progeny. Radiat. Prot. Dosim. 160, 96-99 (2014)
Irlinger, J.°, Wielunski, M., Rühm, W.: Thoron detection with an active Radon exposure meter - first results.
Rev. Sci. Instruments 85:022106 (2014)
Ivanov, D.V.°, Wieser, A., Shishkina, E.A., Ustinov, V.V.: Effect of spectrum processing procedure on the
linearity of EPR dose reconstruction in tooth enamel. Radiat. Meas. 68, 7-13 (2014)
Jacob, P.°, Kaiser, J.C., Ulanovsky, A.: Ultrasonography survey and thyroid cancer in the Fukushima
prefecture. Radiat. Environ. Biophys. 53, 391-401 (2014)
Jaworska, A.°, Ainsbury, E.A., Fattibene, P., Lindholm, C., Oestreicher, U., Rothkamm, K., Romm, H.,
Thierens, H., Trompier, F., Voisin, P., Vral, A., Woda, C., Wojcik, A.: Operational guidance for radiation
emergency response organisations in Europe for using biodosimetric tools developed in EU Multibiodose
project. Radiat. Prot. Dosim. 164, 165-169 (2015) [published online 2014]
Kaiser, J.C.°, Meckbach, R., Jacob, P.: Genomic instability and radiation risk in molecular pathways to
colon cancer. PLoS ONE 9:e111024 (2014)
Karamitros, M.°, Luan, S., Bernal, M.A., Allison, J.P., Baldacchino, G., Davidkova, M., Francis, Z., Friedland,
W., Ivantchenko, V., Ivantchenko, A., Mantero, A., Nieminem, P., Santin, G., Tran, H.N., Stepan, V., Incerti,
S.°: Diffusion-controlled reactions modeling in Geant4-DNA. J. Comput. Phys. 274, 841-882 (2014)
Kulka, U.°, Ainsbury, L., Atkinson, M.J., Barnard, S., Smith, R., Barquinero, J.F., Barrios, L., Bassinet, C.,
Beinke, C., Cucu, A., Darroudi, F., Fattibene, P., Bortolin, E., Monaca, S.D., Gil, O., Gregoire, E.,
Hadjidekova, V., Haghdoost, S., Hatzi, V., Hempel, W., Herranz, R., Jaworska, A., Lindholm, C., Lumniczky,
K., M'kacher, R., Mörtl, S., Montoro, A., Moquet, J., Moreno, M., Noditi, M., Ogbazghi, A., Oestreicher, U.,
Palitti, F., Pantelias, G., Popescu, I., Prieto, M.J., Roch-Lefevre, S., Roessler, U., Romm, H., Rothkamm, K.,
Sabatier, L., Sebastià, N., Sommer, S., Terzoudi, G., Testa, A., Thierens, H., Trompier, F., Turai, I.,
Vandevoorde, C., Vaz, P., Voisin, P., Vral, A., Ugletveit, F., Wieser, A., Woda, C., Wojcik, A.: Realising the
European network of biodosimetry: RENEB - status quo. Radiat. Prot. Dosim. 164, 42-45 (2015) [published
online 2014]
Pan, Y., Qiu, R., Li, J.°, Bi, L., Shang, B., Tschiersch, J.: Integrating high voltage electric field detector for
220Rn progeny. J. Tsinghua Univ. 53, 1380-1384 (2013)
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Rühm, W.°, Mares, V., Pioch, C., Agosteo, S., Endo, A., Ferrarini, M., Rakhno, I., Rollet, S., Satoh, D.,
Vincke, H.: Comparison of Bonner sphere responses calculated by different Monte Carlo codes at energies
between 1 MeV and 1 GeV - potential impact on neutron dosimetry at energies higher than 20 MeV. Radiat.
Meas. 67, 24-34 (2014)
Shinonaga, T.°, Steier, P., Lagos, M., Ohkura, T.: Airborne plutonium and non-natural uranium from the
Fukushima DNPP found at 120 km distance a few days after reactor hydrogen explosions. Environ. Sci.
Technol. 48, 3808-3814 (2014)
Simonetto, C.°, Azizova, T.V., Grigoryeva, E.S., Kaiser, J.C., Schöllnberger, H., Eidemüller, M.: Ischemic
heart disease in workers at Mayak PA: Latency of incidence risk after radiation exposure. PLoS ONE
9:e96309 (2014)
Träber, S.C., Höllriegl, V.°, Li, W.B., Czeslik, U., Rühm, W., Oeh, U., Michalke, B.: Estimating the
absorption of soil-derived uranium in humans. Environ. Sci. Technol. 48, 14721-14727 (2014)
Ulanovsky, A.°: Absorbed doses in tissue-equivalent spheres above radioactive sources in soil. Radiat.
Environ. Biophys. 53, 729-737 (2014)
Vrba, T.°, Nogueira, P., Broggio, D., Caldeira, M., Capello, K., Fantínová, K., Figueira, C., Hunt, J., Leone,
D., Murugan, M., Marzocchi, O., Moraleda, M., Shutt, A.L., Suh, S., Takahashi, M., Tymińska, K., Antonia
Lopez, M., Tanner, R.: EURADOS intercomparison exercise on MC modeling for the in-vivo monitoring of
Am-241 in skull phantoms (Part I). Radiat. Phys. Chem. 104, 332-338 (2014)
Walsh, L.°, Zhang, W., Shore, R.E., Auvinen, A., Laurier, D., Wakeford, R., Jacob, P., Gent, N., Anspaugh,
L.R., Schüz, J., Kesminiene, A., van Deventer, E.T., Tritscher, A.M., del Rosarion Pérez, M.: A framework for
estimating radiation-related cancer risks in Japan from the 2011 Fukushima nuclear accident. Radiat. Res.
182, 556-572 (2014)
Wieser, A.°, Vasilenko, E., Aladova, E., Fattibene, P., Semiochkina, N., Smetanin, M.: Electron
paramagnetic resonance measurements of absorbed dose in teeth from citizens of Ozyorsk. Radiat. Environ.
Biophys. 53, 321-333 (2014)
Wittmaack, K.°, Gnaser, H.: Comprehensive modelling of secondary-ion energy spectra measured with a
magnetic sector field instrument: II. Evaluation of experimental data. Int. J. Mass Spectrom. 358, 49-58
(2014)
Wittmaack, K.°: Novel model of negative secondary ion formation and its use to refine the electronegativity
of almost fifty elements. Anal. Chem. 86, 5962-5968 (2014)
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Institute of Soil Ecology
Bai, M.°, Wilske, B., Buegger, F., Bruun, E.W., Bach, M., Frede, H.-G., Breuer, L.: Biodegradation
measurements confirm the predictive value of the O:C-ratio for biochar recalcitrance. J. Plant Nutr. Soil Sci.
177, 633-637 (2014)
Bai, M., Wilske, B.°, Buegger, F., Esperschütz, J., Bach, M., Frede, H.-G., Breuer, L.: Relevance of
nonfunctional linear polyacrylic acid for the biodegradation of superabsorbent polymer in soils. Environ. Sci.
Pollut. Res. 22, 5444-5452 (2015) [published online 2014]
Bassu, S., Brisson, N., Durand, J.L.°, Boote, K.J., Lizaso, J., Jones, J.W., Rosenzweig, C., Ruane, A.C.,
Adam, M., Baron, C., Basso, B., Biernath, C.J., Boogaard, H., Conijn, S., Corbeels, M., Deryng, D., de
Sanctis, G., Gayler, S., Grassini, P., Hatfield, J.L., Hoek, S., Izaurralde, C., Jongschaap, R., Kemanian, A.R.,
Kersebaum, C.K., Kumar, N.S., Makowski, D., Müller, C., Nendel, C., Priesack, E., Pravia, M.V., Kim, S.H.,
Sau, F., Shcherbak, I., Tao, F., Teixeira, E., Timlin, D., Waha, K.: How do various maize crop models vary in
their responses to climate change factors? Glob. Change Biol. 20, 2301-2320 (2014)
Breulmann, M.°, Masyutenko, N.P., Maratovich Kogut, B., Schroll, R., Dörfler, U., Buscot, F., Schulz, E.:
Short-term bioavailability of carbon in soil organic matter fractions of different particle sizes and densities in
grassland ecosystems. Sci. Total Environ. 497-498, 29-37 (2014)
Eibisch, N., Schroll, R.°, Fuß, R., Mikutta, R., Helfrich, M., Flessa, H.: Pyrochars and hydrochars differently
alter the sorption of the herbicide isoproturon in an agricultural soil. Chemosphere 119, 155-162 (2014)
Hentschel, R., Rosner, S., Kayler, Z.E.°, Andreassen, K., Børja, I., Solberg, S., Tveito, O.E., Priesack, E.,
Gessler, A.: Norway spruce physiological and anatomical predisposition to dieback. Forest Ecol. Manag.
322, 27-36 (2014)
Kastl, E.-M., Schloter-Hai, B., Buegger, F., Schloter, M.°: Impact of fertilization on the abundance of
nitrifiers and denitrifiers at the root-soil interface of plants with different uptake strategies for nitrogen. Biol.
Fertil. Soils 51, 57-64 (2015) [published online 2014]
Mayor, J.°, Bahram, M., Henkel, T., Buegger, F., Pritsch, K., Tedersoo, L.: Ectomycorrhizal impacts on
plant nitrogen nutrition: Emerging isotopic patterns, latitudinal variation and hidden mechanisms. Ecol. Lett.
18, 96-107 (2014)
Mumbo, J., Henkelmann, B., Abdelaziz, A., Pfister, G., Nguyen, N., Schroll, R., Munch, J.-C., Schramm,
K.-W.°: Persistence and dioxin-like toxicity of carbazole and chlorocarbazoles in soil. Environ. Sci. Pollut.
Res. 22, 1344-1356 (2015) [published online 2014]
Pretzsch, H.°, Rötzer, T.°, Matyssek, R., Grams, T.E.E., Häberle, K.-H., Pritsch, K., Kerner, R.C., Munch,
J.-C.: Mixed Norway spruce (Picea abies [L.] Karst) and European beech (Fagus sylvatica [L.]) stands under
drought: From reaction pattern to mechanism. Trees-Struct. Funct. 28, 1305-1321 (2014)
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Institute of Soil Ecology
Steinauer, K.°, Tilman, D., Wragg, P.D., Cesarz, S., Cowles, J.M., Pritsch, K., Reich, P.B., Weisser, W.W.,
Eisenhauer, N.: Plant diversity effects on soil microbial functions and enzymes are stronger than warming in
a grassland experiment. Ecology 96, 99-112 (2015) [published online 2014]
Tedersoo, L.°, Bahram, M., Polme, S., Koljalg, U., Yorou, N.S., Wijesundera, R., Villarreal Ruiz, L.,
Vasco-Palacios, A.M., Thu, P.Q., Suija, A., Smith, M.E., Sharp, C., Saluveer, E., Saitta, A., Rosas, M., Riit,
T., Ratkowsky, D., Pritsch, K., Poldmaa, K., Piepenbring, M., Phosri, C., Peterson, M., Parts, K., Pärtel, K.,
Otsing, E., Nouhra, E., Njouonkou, A.L., Nilsson, R.H., Morgado, L.N., Mayor, J., May, T.W., Majuakim, L.,
Lodge, D.J., Lee, S.S., Larsson, K.H., Kohout, P., Hosaka, K., Hiiesalu, I., Henkel, T.W., Harend, H., Guo,
L.D., Greslebin, A., Grelet, G., Geml, J., Gates, G., Dunstan, W., Dunk, C., Drenkhan, R., Dearnaley, J., de
Kesel, A., Dang, T., Chen, X., Buegger, F., Brearley, F.Q., Bonito, G., Anslan, S., Abell, S., Abarenkov, K.:
Global diversity and geography of soil fungi. Science 346:1256688 (2014)
Tedersoo, L.°, Harend, H., Buegger, F., Pritsch, K., Saar, I., Koljalg, U.: Stable isotope analysis, field
observations and synthesis experiments suggest that Odontia is a non-mycorrhizal sister genus of
Tomentella and Thelephora. Fungal Ecol. 11, 80-90 (2014)
Vogel, C.°, Mueller, C.W., Höschen, C., Buegger, F., Heister, K., Schulz, S., Schloter, M., Kögel-Knabner,
I.: Submicron structures provide preferential spots for carbon and nitrogen sequestration in soils. Nat.
Commun. 5:2947 (2014)
Wöhling, T.°, Gayler, S., Priesack, E., Ingwesen, J., Wizemann, H.-D., Högy, P., Cuntz, M., Attinger, S.,
Wulfmeyer, V., Streck, T.: Multiresponse, multiobjective calibration as a diagnostic tool to compare accuracy
and structural limitations of five coupled soil-plant models and CLM3.5. Water Resour. Res. 49, 8200-8221
(2013)
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joint first authors
Institute of Stem Cell Research
Beckervordersandforth, R.°, Deshpande, A., Schäffner, I., Huttner, H.B., Lepier, A., Lie, D.C., Götz, M.: In
vivo targeting of adult neural stem cells in the dentate gyrus by a split-cre approach. Stem Cell Rep. 2,
153-162 (2014)
Bedi, U., Kumar Mishra, V., Wasilewski, D., Scheel, C., Johnsen, S.A.°: Epigenetic plasticity: A central
regulator of epithelial-tomesenchymal transition in cancer. Oncotarget 5, 2016-2029 (2014)
Borrell, V.°, Götz, M.°: Role of radial glial cells in cerebral cortex folding. Curr. Opin. Neurobiol. 27C, 39-46
(2014)
Cabrera, M.C., Tilahun, E., Nakles, R., Diaz-Cruz, E.S., Charabaty, A., Suy, S., Jackson, P., Ley, L., Slack,
R., Jha, R., Collins, S.P., Haddad, N., Kallakury, B.V., Schroeder, T., Pishvaian, M.J., Furth, P.A.°: Human
pancreatic cancer-associated stellate cells remain activated after in vivo chemoradiation. Front. Oncol. 4:102
(2014)
(2014)
Dimou, L., Götz, M.°: Glial cells as progenitors and stem cells: New roles in the healthy and diseased brain.
Physiol. Rev. 94, 709-737 (2014)
Draganova, K., Zemke, M., Zurkirchen, L., Valenta, T., Cantù, C., Okoniewski, M., Schmid, M.-T., Hoffmans,
R., Götz, M., Basler, K., Sommer, L.°: Wnt/β-catenin signaling regulates sequential fate decisions of murine
cortical precursor cells. Stem Cells 33, 170-182 (2015) [published online 2014]
Heinrich, C., Bergami, M., Gascón, S., Lepier, A., Viganò, F., Dimou, L., Sutor, B., Berninger, B.°, Götz,
M.°: Sox2-mediated conversion of NG2 glia into induced neurons in the injured adult cerebral cortex. Stem
Cell Rep. 3, 1000-1014 (2014)
Johansson, P.A.: The choroid plexuses and their impact on developmental neurogenesis. Front. Neurosci.
8:340 (2014)
Keitel, U., Scheel, A., Thomale, J., Halpape, R., Kaulfuß, S., Scheel, C., Dobbelstein, M.°: Bcl-xL mediates
therapeutic resistance of a mesenchymal breast cancer cell subpopulation. Oncotarget 5, 11778-11791
(2014)
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Institute of Stem Cell Research
Ninkovic, J.°, Götz, M.: How to make neurons-thoughts on the molecular logic of neurogenesis in the
central nervous system. Cell Tissue Res. 359, 5-16 (2015) [published online 2014]
(2014)
Schmid, M.-T., Weinandy, F., Wilsch-Bräuninger, M., Huttner, W.B., Cappello, S.°, Götz, M.°: The role of
α-E-catenin in cerebral cortex development: Radial glia specific effect on neuronal migration. Front. Cell.
Neurosci. 8:215 (2014)
Xapelli, S.#°, Agasse, F.#, Grade, S., Bernardino, L., Ribeiro, F.F., Schitine, C.S., Heimann, A.S., Ferro, E.S.,
Sebasti, A.M., de Melo Reis, R.A., Malva, J.O.°: Modulation of subventricular zone oligodendrogenesis: A
role for hemopressin? Front. Cell. Neurosci. 8:59 (2014)
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Development 141, 514-525 (2014)
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Institute of Structural Biology
Akimoto, M., Zhang, Z., Boulton, S., Selvaratnam, R., van Schouwen, B., Gloyd, M., Accili, E.A., Lange,
O.F., Melacini, G.°: A mechanism for the auto-inhibition of Hyperpolarization-activated Cyclic
Nucleotide-gated (HCN) channel opening and its relief by cAMP. J. Biol. Chem. 289, 22205-22220 (2014)
Ammon, T., Mishra, S.K., Kowalska, K., Popowicz, G.M., Holak, T.A., Jentsch, S.°: The conserved
ubiquitin-like protein Hub1 plays a critical role in splicing in human cells. J. Mol. Cell Biol. 6, 312-323 (2014)
Arciniega, M.°, Lange, O.F.: Improvement of virtual screening results by docking data feature analysis. J.
Chem. Inf. Model. 54, 1401-1411 (2014)
Brandmaier, S.°, Tetko, I.V.: Robustness in experimental design: A study on the reliability of selection
approaches. Comp. Struc. Biotech. J. 7:e201305002 (2013)
Brandmaier, S., Peijnenburg, W., Durjava, M.K., Kolar, B., Gramatica, P., Papa, E., Bhhatarai, B., Kovarich,
S., Cassani, S., Roy, P.P., Rahmberg, M., Öberg, T., Jeliazkova, N., Golsteijn, L., Comber, M., Charochkina,
L., Novotarskyi, S., Sushko, I., Abdelaziz, A., D'Onofrio, E., Kunwar, P., Ruggiu, F., Tetko, I.V.°: The
QSPR-THESAURUS: The online platform of the CADASTER project. ATLA-Altern. Lab. Anim. 42, 13-24
(2014)
Cassotti, M., Ballabio, D.°, Consonni, V., Mauri, A., Tetko, I.V., Todeschini, R.: Prediction of acute aquatic
toxicity toward Daphnia magna by using the GA-kNN method. ATLA-Altern. Lab. Anim. 42, 31-41 (2014)
Dallmann, A., Sattler, M.: Detection of hydrogen bonds in dynamic regions of RNA by NMR spectroscopy.
Curr. Protoc. Nucleic Acid Chem., DOI: 10.1002/0471142700.nc0722s59 (2014)
Feige, M.J.#°, Gräwert, M.A.#, Marcinowski, M.#, Hennig, J.#, Behnke, J., Ausländer, D., Herold, E.M.,
Peschek, J., Castro, C.D., Flajnik, M., Hendershot, L.M., Sattler, M., Groll, M., Buchner, J.: The structural
analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins. Proc. Natl. Acad. Sci.
U.S.A. 111, 8155-8160 (2014)
Göbl, C., Madl, T.°, Simon, B., Sattler, M.°: NMR approaches for structural analysis of multidomain proteins
and complexes in solution. Prog. Nucl. Magn. Reson. Spectrosc. 80, 26-63 (2014)
Hennig, J., Gebauer, F., Sattler, M.°: Breaking the protein-RNA recognition code. Cell Cycle 13, 3619-3620
(2014)
Hennig, J., Militti, C., Popowicz, G.M., Wang, I., Sonntag, M., Geerlof, A., Gabel, F., Gebauer, F.°, Sattler,
M.°: Structural basis for the assembly of the Sxl-Unr translation regulatory complex. Nature 515, 287-290
(2014)
Hennig, J., Sattler, M.°: The dynamic duo: Combining NMR and small angle scattering in structural biology.
Protein Sci. 23, 669-682 (2014)
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Huang, J., Warner, L.R., Sanchez, C., Gabel, F., Madl, T., Mackereth, C.D., Sattler, M.°, Blackledge,
M.J.°: Transient electrostatic interactions dominate the conformational equilibrium sampled by multidomain
splicing factor U2AF65: A combined NMR and SAXS study. J. Am. Chem. Soc. 136, 7068-7076 (2014)
Huang, Y., Wolf, S., Beck, B., Köhler, L.-M., Khoury, K., Popowicz, G.M., Goda, S.K., Subklewe, M.,
Twarda, A., Holak, T.A., Dömling, A.°: Discovery of highly potent p53-MDM2 antagonists and structural basis
for anti-acute myeloid leukemia activities. ACS Chem. Biol. 9, 802-811 (2014)
Jacso, T., Bardiaux, B., Broecker, J., Fiedler, S., Baerwinkel, T., Mainz, A., Fink, U., Vargas, C., Oschkinat,
H., Keller, S.°, Reif, B.°: The mechanism of denaturation and the unfolded state of the α-helical
membrane-associated protein Mistic. J. Am. Chem. Soc. 135, 18884-18891 (2013)
Jansen, R.P., Niessing, D., Baumann, S., Feldbrügge, M.°: MRNA transport meets membrane traffic.
Trends Genet. 30, 408-417 (2014)
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Jeltsch, K. , Hu, D. , Brenner, S. , Zöller, J., Heinz, G.A., Nagel, D., Vogel, K.U., Rehage, N., Warth,
Immunol. 15, 1079-1089 (2014)
Karagöz, G.E., Duarte, A.M., Akoury, E., Ippel, H., Biernat, J., Morán Luengo, T., Radli, M., Didenko, T.,
Nordhues, B.A., Veprintsev, D.B., Dickey, C.A., Mandelkow, E.-M., Zweckstetter, M., Boelens, R., Madl, T.°,
Rüdiger, S.G.°: Hsp90-tau complex reveals molecular basis for specificity in chaperone action. Cell 156,
963-974 (2014)
Kireeva, N.V.°, Ovchinnikova, S.I., Tetko, I.V., Asiri, A.M., Balakin, K.V., Tsivadze, A.Y.: Nonlinear
dimensionality reduction for visualizing toxicity data: Distance-based versus topology-based approaches.
ChemMedChem 9, 1047-1059 (2014)
Lange, O.F.°: Automatic NOESY assignment in CS-RASREC-Rosetta. J. Biomol. NMR 59, 147-159 (2014)
Linser, R., Sarkar, R., Krushelnitzky, A., Mainz, A., Reif, B.°: Dynamics in the solid-state: Perspectives for
the investigation of amyloid aggregates, membrane proteins and soluble protein complexes. J. Biomol. NMR
59, 1-14 (2014)
Loedige, I.°, Stotz, M., Qamar, S., Kramer, K., Hennig, J., Schubert, T., Loeffler, P., Längst, G., Merkl, R.,
Urlaub, H., Meister, G.°: The NHL domain of BRAT is an RNA-binding domain that directly contacts the
hunchback mRNA for regulation. Genes Dev. 28, 749-764 (2014)
Lopez del Amo, J.M., Agarwal, V., Sarkar, R., Porter, J., Asami, S., Rübbelke, M., Fink, U., Xue, Y.,
Lange, O.F., Reif, B.°: Site-specific analysis of heteronuclear Overhauser effects in microcrystalline
proteins. J. Biomol. NMR 59, 241-249 (2014)
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Lorenz, O.R., Freiburger, L., Rutz, D.A., Krause, M., Zierer, B.K., Alvira, S., Cuéllar, J., Valpuesta, J.M.,
Madl, T.°, Sattler, M.°, Buchner, J.°: Modulation of the Hsp90 chaperone cycle by a stringent client protein.
Mol. Cell 53, 941-953 (2014)
Lou, C., Dallmann, A., Geo, R., Brown, T.C.°: Enhanced H-bonding and π-stacking in DNA: A potent
duplex-stabilizing and mismatch sensing nucleobase analogue. Chem. Sci. 5, 3836-3844 (2014)
Muda, K., Bertinetti, D., Gesellchen, F., Hermann, J.S., von Zweydorf, F., Geerlof, A., Jacob, A., Ueffing,
M., Gloeckner, C.J., Herberg, F.W.°: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA
phosphorylation of LRRK2 and disrupts its interaction with 14-3-3. Proc. Natl. Acad. Sci. U.S.A. 111,
E34-E43 (2014)
Niedner, A., Edelmann, F, Niessing, D.°: Of social molecules: The interactive assembly of ASH1
mRNA-transport complexes in yeast. RNA Biol. 11, 998-1009 (2014)
2147-2161 (2014)
Potukuchi, H.K., Bach, T.°: Selective C-2 alkylation of tryptophan by a Pd(II)/norbornene-promoted C-H
activation reaction. J. Org. Chem. 78, 12263-12267 (2013)
Pustelny, K., Zdzalik, M., Stach, N., Stec-Niemczyk, J., Cichon, P., Czarna, A., Popowicz, G.M., Mak, P.,
Dra̧g, M., Salvesen, G.S., Władyka, B., Potempa, J.S., Dubin, A., Dubin, G.°: Staphylococcal SplB serine
protease utilizes a novel molecular mechanism of activation. J. Biol. Chem. 289, 15544-15553 (2014)
Rodriguez Camargo, D.C., Tripsianes, K., Kapp, T.G., Mendes, J., Schubert, J., Cordes, B., Reif, B.°:
Cloning, expression and purification of the human Islet Amyloid Polypeptide (hIAPP) from Escherichia coli.
Protein Expr. Purif. 106, 49-56 (2015)
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Schilling, F. , Warner, L.R. , Gershenzon, N.I., Skinner, T.E.°, Sattler, M.°, Glaser, S.J.°: Next-generation
heteronuclear decoupling for high-field biomolecular NMR spectroscopy. Angew. Chem.-Int. Edit. 53,
4475-4479 (2014)
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Schlundt, A. , Heinz, G.A. , Janowski, R. , Geerlof, A., Stehle, R., Heissmeyer, V.°, Niessing, D.°,
Sattler, M.°: Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Nat. Struct. Mol. Biol. 21, 671-678 (2014)
Schorpp, K.K.#, Rothenaigner, I.#, Salmina, E., Reinshagen, J., Low, T., Brenke, J.K., Gopalakrishnan, J.,
Tetko, I.V., Gul, S., Hadian, K.°: Identification of small-molecule frequent hitters from AlphaScreen
high-throughput screens. J. Biomol. Screen. 19, 715-726 (2013)
Sommer, L.A., Dames, S.A.°: Characterization of residue-dependent differences in the peripheral membrane
association of the FATC domain of the kinase 'target of rapamycin' by NMR and CD spectroscopy. FEBS
Lett. 588, 1755-1766 (2014)
Sommer, L.A., Janke, J., Bennett, W.F., Bürck, J., Ulrich, A.S., Tieleman, D.P., Dames, S.A.°:
Characterization of the immersion properties of the peripheral membrane anchor of the FATC domain of the
kinase "Target of rapamycin" by NMR, oriented CD spectroscopy, and MD simulations. J. Phys. Chem. B
118, 4817-4831 (2014)
Tetko, I.V.°, Sushko, Y., Novotarskyi, S., Patiny, L., Kondratov, I., Petrenko, A.E., Charochkina, L., Asiri,
A.M.: How accurately can we predict the melting points of drug-like compounds? J. Chem. Inf. Model. 54,
3320-3329 (2014)
Tripsianes, K.°, Friberg, A., Barrandon, C., Brooks, M., van Tilbeurgh, H., Séraphin, B., Sattler, M.°: A novel
protein-protein interaction in the RES (REtention and Splicing) complex. J. Biol. Chem. 289, 28640-28650
(2014)
Vorberg, S., Tetko, I.V.°: Modeling the biodegradability of chemical compounds using the Online Chemical
Modeling environment (OCHEM). Mol. Inf. 33, 73-85 (2014)
Wang, I., Hennig, J., Jagtap, P.K., Sonntag, M., Valcárcel, J., Sattler, M.°: Structure, dynamics and RNA
binding of the multi-domain splicing factor TIA-1. Nucleic Acids Res. 42, 5949-5966 (2014)
Zhang, Z., Porter, J., Tripsianes, K., Lange, O.F.°: Robust and highly accurate automatic NOESY
assignment and structure determination with Rosetta. J. Biomol. NMR 59, 135-145 (2014)
Zierer, B.K., Weiwad, M., Rübbelke, M., Freiburger, L., Fischer, G.S., Lorenz, O.R., Sattler, M., Richter,
K.H.°, Buchner, J.°: Artificial accelerators of the molecular chaperone Hsp90 facilitate rate-limiting
conformational transitions. Angew. Chem.-Int. Edit. 53, 12257-12262 (2014)
page 211 of 247
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Institute of Virology
Boettcher, S., Gerosa, R., Radpour, R., Bauer, J., Ampenberger, F., Heikenwälder, M., Kopf, M., Manz,
M.G.°: Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis. Blood 124,
1393-1403 (2014)
Bohne, F.#, Londoño, M.C.#, Benítez, C., Miquel, R., Martínez-Llordella, M., Russo, C., Ortiz, C.,
Bonaccorsi-Riani, E., Brander, C., Bauer, T., Protzer, U., Jaeckel, E., Taubert, R., Forns, X., Navasa, M.,
Berenguer, M., Rimola, A., Lozano, J.J., Sánchez-Fueyo, A.°: HCV-induced immune responses influence the
development of operational tolerance after liver transplantation in humans. Sci. Transl. Med. 6:242ra81
(2014)
Bolduan, S., Reif, T., Schindler, M.°, Schubert, U.°: HIV-1 Vpu mediated downregulation of CD155 requires
alanine residues 10, 14 and 18 of the transmembrane domain. Virology 464-465, 375-384 (2014)
Eisele, Y.S.#°, Fritschi, S.K.#, Hamaguchi, T.#, Obermüller, U., Füger, P., Skodras, A., Schäfer, C., Odenthal,
J., Heikenwälder, M., Staufenbiel, M., Jucker, M.°: Multiple factors contribute to the peripheral induction of
cerebral β-amyloidosis. J. Neurosci. 34, 10264-10273 (2014)
Franceschi, V., Stellari, F.F., Mangia, C., Jacca, S., Lavrentiadou, S., Cavirani, S., Heikenwälder, M.,
Donofrio, G.°: In vivo image analysis of BoHV-4-based vector in mice. PLoS ONE 9:e95779 (2014)
Friemel, J., Rechsteiner, M.P., Frick, L., Boehm, F., Struckmann, K., Sigg, M., Moch, H., Heikenwälder, M.,
Weber, A.°: Intratumor heterogeneity in hepatocellular carcinoma. Clin. Cancer Res. 21, 1951-1961 (2015)
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Gautheron, J. , Vucur, M. , Reisinger, F. , Cardenas, D.V., Roderburg, C., Koppe, C., Kreggenwinkel, K.,
Schneider, A.T., Bartneck, M., Neumann, U.P., Canbay, A., Reeves, H.L., Luedde, M., Tacke, F., Trautwein,
C., Heikenwälder, M., Luedde, T.°: A positive feedback loop between RIP3 and JNK controls non-alcoholic
steatohepatitis. EMBO Mol. Med. 6, 1062-1074 (2014)
Gnirß, K., Fiedler, M., Krämer-Kühl, A., Bolduan, S., Mittler, E., Becker, S., Schindler, M., Pöhlmann, S.°:
Analysis of determinants in filovirus glycoproteins required for tetherin antagonism. Viruses 6, 1654-1671
(2014)
Graef, P.#, Buchholz, V.R.#, Stemberger, C., Flossdorf, M., Henkel, L., Schiemann, M., Drexler, I., Höfer, T.,
Riddell, S.R., Busch, D.H.°: Serial transfer of single-cell-derived immunocompetence reveals stemness of
CD8+ central memory T cells. Immunity 41, 116-126 (2014)
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Hagen, N. , Bayer, K. , Roesch, K., Schindler, M.°: The intra viral protein interaction network of hepatitis C
virus. Mol. Cell. Proteomics 13, 1676-1689 (2014)
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Heikenwälder, M.°, Protzer, U.°: LINE(1)s of evidence in HBV-driven liver cancer. Cell Host Microbe 15,
249-250 (2014)
Helfer, M., Koppensteiner, H., Schneider, M., Rebensburg, S., Forcisi, S., Müller, C., Schmitt-Kopplin,
P., Schindler, M., Brack-Werner, R.°: The root extract of the medicinal plant Pelargonium sidoides is a
potent HIV-1 attachment inhibitor. PLoS ONE 9:e87487 (2014)
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Hösel, M. , Lucifora, J. , Michler, T., Holz, G., Gruffaz, M., Stahnke, S., Zoulim, F., Durantel, D.,
Heikenwälder, M., Nierhoff, D., Millet, R., Salvetti, A., Protzer, U.°, Buning, H.°: Hepatitis B virus infection
enhances susceptibility towards adeno-associated viral vector transduction in vitro and in vivo. Hepatology
59, 2110-2120 (2014)
Jeltsch, K.#, Hu, D.#, Brenner, S.#, Zöller, J., Heinz, G.A., Nagel, D., Vogel, K.U., Rehage, N., Warth,
Immunol. 15, 1079-1089 (2014)
Kremb, S.°, Helfer, M., Kraus, B., Wolff, H., Wild, C., Schneider, M., Voolstra, C.R., Brack-Werner, R.:
Aqueous extracts of the marine brown alga Lobophora variegata inhibit HIV-1 infection at the level of virus
entry into cells. PLoS ONE 9:e103895 (2014)
Lucifora, J.°, Xia, Y., Reisinger, F., Stadler, D., Heikenwälder, M., Protzer, U.°: Dégradation spécifique de
l´ADN nucléaire responsable de la persistance du virus de l´hépatite B. Med. Sci. (Paris) 30, 724-726 (2014)
Lucifora, J.#, Xia, Y.#, Reisinger, F., Zhang, K., Stadler, D., Cheng, X., Sprinzl, M.F., Koppensteiner, H.,
Makowska, Z., Volz, T., Remouchamps, C., Chou, W.-M., Thasler, W.E., Hüser, N., Durantel, D., Liang, T.J.,
Münk, C., Heim, M.H., Browning, J.L., Dejardin, E., Dandri, M., Schindler, M., Heikenwälder, M.°, Protzer,
U.°: Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA. Science 343, 1221-1228
(2014)
Nehls, J., Koppensteiner, H., Brack-Werner, R., Floss, T., Schindler, M.: HIV-1 replication in human
immune cells is independent of TAR DNA binding Protein 43 (TDP-43) expression. PLoS ONE 9:e105478
(2014)
Odendahl, M.#, Grigoleit, G.U.#, Bönig, H., Neuenhahn, M., Albrecht, J., Anderl, F., Germeroth, L., Schmitz,
M., Bornhäuser, M., Einsele, H., Seifried, E., Busch, D.H., Tonn, T.°: Clinical-scale isolation of 'minimally
manipulated' cytomegalovirus-specific donor lymphocytes for the treatment of refractory cytomegalovirus
disease. Cytotherapy 16, 1245-1256 (2014)
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Protzer, U., Böhm, F., Longerich, T., Seebach, J., Heidary Navid, M., Friemel, J., Marques-Maggio, E.,
Bawohl, M., Heikenwälder, M., Schirmacher, P., Dutkowski, P., Clavien, P.A., Schemmer, P., Schnitzler, P.,
Gotthardt, D., Müllhaupt, B., Weber, A.°: Molecular detection of Hepatitis E Virus (HEV) in liver biopsies after
liver transplantation. Mod. Pathol. 28, 523-532 (2015) [published online 2014]
Ringelhan, M., Protzer, U., O'Connor, T., Heikenwälder, M.°: The direct and indirect role of HBV in liver
cancer: Prospective markers for HCC-screening and potential therapeutic targets. J. Pathol. 235, 355-367
Roth, S., Rottach, A., Lotz-Havla, A.S., Laux, V., Muschaweckh, A., Gersting, S.W., Muntau, A.C., Hopfner,
K.P., Jin, L., Vanness, K., Petrini, J.H., Drexler, I., Leonhardt, H., Ruland, J.°: Rad50-CARD9 interactions
link cytosolic DNA sensing to IL-1β production. Nat. Immunol. 15, 538-545 (2014)
Schittl, B., Bruss, V.°: Mutational profiling of the variability of individual amino acid positions in the hepatitis
B virus matrix domain. Virology 458-459, 183-189 (2014)
Schölzel, K., Schildberg, F.A., Welz, M., Borner, C., Geiger, S., Kurts, C., Heikenwälder, M., Knolle, P.A.,
Wohlleber, D.: Transfer of MHC-class-I molecules among liver sinusoidal cells facilitates hepatic immune
surveillance. J. Hepatol. 61, 600-608 (2014)
Seleznik, G.M., Zöller, J., O'Connor, T., Graf, R., Heikenwälder, M.°: The role of lymphotoxin signaling in
the development of autoimmune pancreatitis and associated secondary extra-pancreatic pathologies.
Cytokine Growth Factor Rev. 25, 125-137 (2014)
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Seubert, B. , Cui, H. , Simonavicius, N., Honert, K., Schafer, S., Reuning, U., Heikenwälder, M., Mari, B.,
Krüger, A.°: Tetraspanin CD63 acts as a pro-metastatic factor via β-catenin stabilization. Int. J. Cancer 136,
Seubert, B.#, Grünwald, B.#, Kobuch, J.#, Cui, H.#, Schelter, F., Schaten, S., Siveke, J.T., Lim, N.H., Nagase,
H., Simonavicius, N., Heikenwälder, M., Reinheckel, T., Sleeman, J.P., Janssen, K.P., Knolle, P.A.,
Krüger, A.°: TIMP-1 creates a pre-metastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil
recruitment in mice. Hepatology 61, 238-248 (2015) [published online 2014]
Sprinzl, M.F., Puschnik, A., Schlitter, A.M., Schad, A., Ackermann, K., Esposito, I., Lang, H., Galle, P.R.,
Weinmann, A., Heikenwälder, M., Protzer, U.°: Sorafenib inhibits macrophage-induced growth of hepatoma
cells by interference with insulin-like growth factor-1 secretion. J. Hepatol. 62, 863-870 (2015) [published
online 2014]
Stemberger, C., Graef, P., Odendahl, M., Albrecht, J., Doessinger, G., Anderl, F., Buchholz, V.R.,
Gasteiger, G., Schiemann, M., Grigoleit, G.U., Schuster, F.R., Borkhardt, A., Versluys, B., Tonn, T.,
Seifried, E., Einsele, H., Germeroth, L., Busch, D.H., Neuenhahn, M.°: Lowest numbers of primary CD8+ T
cells can reconstitute protective immunity upon adoptive immunotherapy. Blood 124, 628-637 (2014)
Unger, K., Heikenwälder, M.°: Analysis of chromosomal aberrations in murine HCC. Methods Mol. Biol.
1193, 213-226 (2014)
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Waldschmitt, N., Berger, E., Rath, E., Sartor, R.B., Weigmann, B., Heikenwälder, M., Gerhard, M., Janssen,
K.P., Haller, D.°: C/EBP homologous protein inhibits tissue repair in response to gut injury and is inversely
regulated with chronic inflammation. Mucosal Immunol. 7, 1452-1466 (2014)
Wisskirchen, K., Lucifora, J., Michler, T., Protzer, U.°: New pharmacological strategies to fight enveloped
viruses. Trends Pharmacol. Sci. 35, 470-478 (2014)
+
Wuestenberg, A.#, Kah, J.#, Singethan, K., Sirma, H., Keller, A.D., Rosal, S.R., Schrader, J., Loscher, C.,
Volz, T., Bartenschlager, R., Lohmann, V., Protzer, U., Dandri, M., Lohse, A.W., Tiegs, G., Sass, G.°: Matrix
conditions and KLF2-dependent induction of heme oxygenase-1 modulate inhibition of HCV replication by
fluvastatin. PLoS ONE 9:e96533 (2014)
Yabal, M., Müller, N., Adler, H., Knies, N., Groß, C.J., Damgaard, R.B., Kanegane, H., Ringelhan, M.,
Kaufmann, T., Heikenwälder, M., Strasser, A., Groß, O., Ruland, J., Peschel, C., Gyrd-Hansen, M., Jost,
P.J.°: XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation. Cell Rep. 7,
1796-1808 (2014)
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Research Unit Analytical BioGeoChemistry
Boncompain, G., Müller, C., Meas-Yedid, V., Schmitt-Kopplin, P., Lazarow, P.B.°, Subtil, A.: The
intracellular bacteria Chlamydia hijack peroxisomes and utilize their enzymatic capacity to produce
bacteria-specific phospholipids. PLoS ONE 9:e86196 (2014)
Börjesson, K., Ćoso, D., Gray, V., Grossman, J.C., Guan, J., Harris, C.B., Hertkorn, N., Hou, Z., Kanai, Y.,
Lee, D., Lomont, J.P., Majumdar, A.K., Meier, S.K., Moth-Poulsen, K., Myrabo, R.L., Nguyen, S.C.,
Segalman, R.A., Srinivasan, V.S., Tolman, W.B., Vinokurov, N.A., Vollhardt, K.P.C.°, Weidman, T.W.:
Exploring the potential of fulvalene dimetals as platforms for molecular solar thermal energy storage:
Computations, syntheses, structures, kinetics, and catalysis. Chem. Eur. J. 20, 15587-15604 (2014)
6373-6383 (2014)
Cortés-Francisco, N.°, Harir, M., Lucio, M., Ribera, G., Martínez-Lladó, X., Rovira, M., Schmitt-Kopplin, P.,
Hertkorn, N.°, Caixach, J.: High-field FT-ICR mass spectrometry and NMR spectroscopy to characterize
DOM removal through a nanofiltration pilot plant. Water Res. 67, 154-165 (2014)
Dubinenkov, I.V.°, Flerus, R., Schmitt-Kopplin, P., Kattner, G.G., Koch, B.P.: Origin-specific molecular
signatures of dissolved organic matter in the Lena Delta. Biogeochemistry 123, 1-14 (2015) [published online
2014]
Fernsebner, K.°, Zorn, J., Kanawati, B., Walker, A., Michalke, B.: Manganese leads to an increase in
markers of oxidative stress as well as to a shift in the ratio of Fe(ιι)/(ιιι) in rat brain tissue. Metallomics 6,
921-931 (2014)
Gonsior, M.°, Schmitt-Kopplin, P., Stavklint, H., Richardson, S.D., Hertkorn, N., Bastviken, D.: Dissolved
organic matter changes along treatments of a drinking water plant in Sweden and the formation of previously
unknown DBPs. Environ. Sci. Technol. 48, 12714-12722 (2014)
Gonsior, M.°, Hertkorn, N., Conte, M.H., Cooper, W.J., Bastviken, D., Druffel, E., Schmitt-Kopplin, P.:
Photochemical production of polyols arising from significant photo-transformation of dissolved organic matter
in the oligotrophic surface ocean. Mar. Chem. 163, 10-18 (2014)
Green, N.W., McInnis, D., Hertkorn, N., Maurice, P.A., Perdue, E.M.°: Suwannee River natural organic
matter: Isolation of the 2R101N reference sample by reverse osmosis. Environ. Eng. Sci. 32, 38-44 (2015)
He, Y., Harir, M., Chen, G., Gougeon, R.D., Zhang, L., Huang, X., Schmitt-Kopplin, P.°: Capillary
Electrokinetic Fractionation Mass Spectrometry (CEkF/MS): Technology setup and application to metabolite
fractionation from complex samples coupled at-line with ultrahigh resolution mass spectrometry.
Electrophoresis 35, 1965-1975 (2014)
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joint first authors
Helfer, M., Koppensteiner, H., Schneider, M., Rebensburg, S., Forcisi, S., Müller, C., Schmitt-Kopplin,
P., Schindler, M., Brack-Werner, R.°: The root extract of the medicinal plant Pelargonium sidoides is a
potent HIV-1 attachment inhibitor. PLoS ONE 9:e87487 (2014)
Herzsprung, P.°, Hertkorn, N., von Tümpling, W., Harir, M., Friese, K., Schmitt-Kopplin, P.: Understanding
molecular formula assignment of Fourier transform ion cyclotron resonance mass spectrometry data of
natural organic matter from a chemical point of view. Anal. Bioanal. Chem. 406, 7977-7987 (2014)
Jenniskens, P.°, Rubin, A.E., Yin, Q.Z., Sears, D.W.G, Sandford, S.A., Zolensky, M.E., Krot, A.N., Blair, L.,
Kane, D., Utas, J., Verish, R., Friedrich, J.M., Wimpenny, J., Eppich, G.R., Ziegler, K., Verosub, K.L.,
Rowland, D.J., Albers, J., Gural, P.S., Grigsby, B., Fries, M.D., Matson, R., Johnston, M., Silber, S., Brown,
P., Yamakawa, A., Sanborn, M.E., Laubenstein, M., Welten, K.C., Nishiizumi, K., Meier, M.M.M, Busemann,
H., Clay, P., Caffee, M.W., Schmitt-Kopplin, P., Hertkorn, N., Glavin, D.P., Callahan, M.P., Dworkin, J.P.,
Wu, Q., Zare, R.N., Grady, M., Verchovsky, S., Emel'yanenko, V., Naroenkov, S., Clark, D.L., Girten, B.,
Worden, P.S., Novato Meteorite Consortium: Fall, recovery, and characterization of the Novato L6 chondrite
breccia. Meteorit. Planet. Sci. 49, 1388-1425 (2014)
Kanawati, B.°, Wanczek, K.-P.: Phosphoranide production and decomposition in the gas phase. Int. J. Mass
Spectrom. 362, 18-23 (2014)
1361, 209-216 (2014)
Lechtenfeld, O.J., Kattner, G., Flerus, R., McCallister, S.L., Schmitt-Kopplin, P., Koch, B.P.°: Molecular
transformation and degradation of refractory dissolved organic matter in the Atlantic and Southern Ocean.
Geochim. Cosmochim. Acta 126, 321-337 (2014)
Lyubenova, L., Bipuah, H., Belford, E.J., Michalke, B., Winkler, B., Schröder, P.°: Comparative study on
the impact of copper sulphate and copper nitrate on the detoxification mechanisms in Typha latifolia.
Environ. Sci. Pollut. Res. 22, 657-666 (2015) [published online 2014]
Meckenstock, R.U.°, von Netzer, F., Stumpp, C., Lueders, T., Himmelberg, A.M., Hertkorn, N.,
Schmitt-Kopplin, P., Harir, M., Hosein, R., Haque, S., Schulze-Makuch, D.: Water droplets in oil are
microhabitats for microbial life. Science 345, 673-676 (2014)
page 217 of 247
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Michalke, B.°: Anwendung der Platinspeziation zum Nachweis einer Aktivierung oder Inhibierung von Pt
enthaltenden Krebsmedikamenten. Perspect. Med. 2, 79-90 (2014)
Michalke, B., Witte, H.: Characterization of a rapid and reliable method for iodide biomonitoring in serum
and urine based on ion chromatography-ICP-mass spectrometry. J. Trace Elem. Med. Biol. 29, 63-68 (2014)
Michalke, B., Fernsebner, K.°: Neue Einsichten in die Toxizität und die Speziation von Mangan. Perspect.
Med. 2, 109-124 (2014)
Michalke, B., Rossbach, B., Göen, T.°, Schäferhenrich, A., Scherer, G.: Saliva as a matrix for human
biomonitoring in occupational and environmental medicine. Int. Arch. Occup. Environ. Health 88, 1-44 (2015)
Mubark Ebrahim, A.°, Etayeb, M.A., Khalid, H., Noun, M., Roumie, M., Michalke, B.: PIXE as a complement
to ICP-OES trace metal analysis in Sudanese medicinal plants. Appl. Radiat. Isot. 90, 218-224 (2014)
Müller, C.#, Kanawati, B.#, Rock, T.#, Forcisi, S.#, Moritz, F.#, Schmitt-Kopplin, P.#: Dimer ion formation
and intermolecular fragmentation of 1,2-diacylglycerols revealed by electrospray ionization Fourier transform
ion cyclotron resonance mass spectrometry for more comprehensive lipid analysis. Rapid Commun. Mass
Spectrom. 28, 1735-1744 (2014)
Roullier-Gall, C., Boutegrabet, L., Gougeon, R.D.°, Schmitt-Kopplin, P.°: A grape and wine chemodiversity
comparison of different appellations in Burgundy: Vintage vs terroir effects. Food Chem. 152, 100-107 (2014)
Roullier-Gall, C., Lucio, M., Noret, L., Schmitt-Kopplin, P.°, Gougeon, R.D.°: How subtle is the "Terroir"
effect? Chemistry-related signatures of two "Climats de Bourgogne". PLoS ONE 9:e97615 (2014)
Sippula, O.°, Stengel, B., Sklorz, M., Streibel, T., Rabe, R., Orasche, J., Lintelmann, J., Michalke, B.,
Abbaszade, G., Radischat, C., Gröger, T.M., Schnelle-Kreis, J., Harndorf, H., Zimmermann, R.: Particle
emissions from a marine engine: Chemical composition and aromatic emission profiles under various
operating conditions. Environ. Sci. Technol. 48, 11721-11729 (2014)
Tang, Z., Li, S., Guan, X., Schmitt-Kopplin, P., Lin, S., Cai, Z.°: Rapid assessment of the coenzyme Q10
redox state using ultrahigh performance liquid chromatography tandem mass spectrometry. Analyst 139,
5600-5604 (2014)
Thondamal, M., Witting, M., Schmitt-Kopplin, P., Aguilaniu, H.°: Steroid hormone signalling links
reproduction to lifespan in dietary-restricted Caenorhabditis elegans. Nat. Commun. 5:4879 (2014)
page 218 of 247
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(2014)
Wittek, F., Hoffmann, T., Kanawati, B., Bichlmeier, M., Knappe, C., Wenig, M., Schmitt-Kopplin, P.,
Parker, J.E., Schwab, W., Vlot, A.C.°: Arabidopsis ENHANCED DISEASE SUSCEPTIBILITY1 promotes
systemic acquired resistance via azelaic acid and its precursor 9-oxo nonanoic acid. J. Exp. Bot. 65,
5919-5931 (2014)
Wittek, F., Kanawati, B., Wenig, M., Hoffmann, T., Franz-Oberdorf, K., Schwab, W., Schmitt-Kopplin, P.,
Vlot, A.C.°: Folic acid induces salicylic acid-dependent immunity in Arabidopsis and enhances susceptibility
to Alternaria brassicicola. Mol. Plant Pathol. 16, 616-622 (2015) [published online 2014]
Witting, M.°, Lucio, M., Tziotis, D., Wägele, B., Suhre, K., Voulhoux, R., Garvis, S., Schmitt-Kopplin, P.:
DI-ICR-FT-MS-based high-throughput deep metabotyping: A case study of the Caenorhabditis
elegans-Pseudomonas aeruginosa infection model. Anal. Bioanal. Chem. 407, 1059-1073 (2015) [published
online 2014]
Witting, M.°, Maier, T.V., Garvis, S., Schmitt-Kopplin, P.: Optimizing a ultrahigh pressure liquid
chromatography-time of flight-mass spectrometry approach using a novel sub-2µm core-shell particle for in
depth lipidomic profiling of Caenorhabditis elegans. J. Chromatogr. A 1359, 91-99 (2014)
Witting, M., Schmitt-Kopplin, P.°: Transcriptome and metabolome data integration-technical perquisites for
successful data fusion and visualization. Compr. Anal. Chem. 63, 421-442 (2014)
Yassine, M.M.°, Harir, M., Dabek-Zlotorzynska, E., Schmitt-Kopplin, P.: Structural characterization of
organic aerosol using Fourier transform ion cyclotron resonance mass spectrometry: Aromaticity equivalent
approach. Rapid Commun. Mass Spectrom. 28, 2445-2454 (2014)
Zhang, F., Harir, M., Moritz, F., Zhang, J., Witting, M., Wu, Y., Schmitt-Kopplin, P., Fekete, A., Gáspár,
A., Hertkorn, N.°: Molecular and structural characterization of dissolved organic matter during and post
cyanobacterial bloom in Taihu by combination of NMR spectroscopy and FTICR mass spectrometry. Water
Res. 57, 280-294 (2014)
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Research Unit Comparative Medicine
Feistenauer, S., Sander, I., Schmidt, J., Zahradnik, E., Raulf, M., Brielmeier, M.°: Influence of 5 different
caging types and the use of cage-changing stations on mouse allergen exposure. J. Amer. Assoc. Lab.
Anim. Sci. 53, 356-363 (2014)
Fernsebner, K.°, Zorn, J., Kanawati, B., Walker, A., Michalke, B.: Manganese leads to an increase in
markers of oxidative stress as well as to a shift in the ratio of Fe(ιι)/(ιιι) in rat brain tissue. Metallomics 6,
921-931 (2014)
Price, P.J., Luckow, B., Torres-Domínguez, L.E., Brandmüller, C., Zorn, J., Kirschning, C.J., Sutter, G.,
Lehmann, M.H.°: Chemokine (C-C motif) receptor 1 (CCR1) is required for efficient recruitment of neutrophils
during respiratory infection with Modified Vaccinia virus Ankara. J. Virol. 88, 10840-10850 (2014)
Price, P.J., Bánki, Z., Scheideler, A., Stoiber, H., Verschoor, A., Sutter, G., Lehmann, M.H.°: Complement
component C5 recruits neutrophils in the absence of C3 during respiratory infection with modified vaccinia
virus Ankara. J. Immunol. 194, 1164-1168 (2015) [published online 2014]
Rowshanravan, B., Woodcock, S.A., Botella, J.A., Kiermayer, C., Schneuwly, S., Hughes, D.A.°: RasGAP
mediates neuronal survival in Drosophila through direct regulation of Rab5-dependent endocytosis. J. Cell
Sci. 127, 2849-2861 (2014)
Schönhuber, N.#, Seidler, B.#, Schuck, K.#, Veltkamp, C.#, Schachtler, C., Zukowska, M., Eser, S.,
Feyerabend, T.B., Paul, M.C., Eser, P., Klein, S., Lowy, A.M., Banerjee, R., Yang, F., Lee, C.L., Moding,
E.J., Kirsch, D.G., Scheideler, A., Alessi, D.R., Varela, I., Bradley, A., Kind, A., Schnieke, A.E., Rodewald,
H.R., Rad, R., Schmid, R.M., Schneider, G., Saur, D.°: A next-generation dual-recombinase system for timeand host-specific targeting of pancreatic cancer. Nat. Med. 20, 1340-1347 (2014)
Wirth, E.K., Bharathi, B.S., Hatfield, D.L., Conrad, M., Brielmeier, M., Schweizer, U.°: Cerebellar hypoplasia
in mice lacking selenoprotein biosynthesis in neurons. Biol. Trace Elem. Res. 158, 203-210 (2014)
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Research Unit Environmental Genomics
®
Babin, D., Vogel, C., Zühlke, S., Schloter, M., Pronk, G.J., Heister, K., Spiteller, M., Kögel-Knabner, I.,
Smalla, K.°: Soil mineral composition matters: Response of microbial communities to phenanthrene and
plant litter addition in long-term matured artificial soils. PLoS ONE 9:e106865 (2014)
Bai, M., Wilske, B.°, Buegger, F., Esperschütz, J., Bach, M., Frede, H.-G., Breuer, L.: Relevance of
nonfunctional linear polyacrylic acid for the biodegradation of superabsorbent polymer in soils. Environ. Sci.
Pollut. Res. 22, 5444-5452 (2015) [published online 2014]
Berg, G.°, Grube, M., Schloter, M., Smalla, K.: The plant microbiome and its importance for plant and
human health. Front. Microbiol. 5:491 (2014)
Berg, G.°, Grube, M., Schloter, M., Smalla, K.: Unraveling the plant microbiome: Looking back and future
perspectives. Front. Microbiol. 5:148 (2014)
Bimüller, C.°, Müller, C.W.°, Lützow, M., Kreyling, O., Kölbl, A., Haug, S., Schloter, M., Knabner, I.K.:
Decoupled carbon and nitrogen mineralization in soil particle size fractions of a forest topsoil. Soil Biol.
Biochem. 78, 263-273 (2014)
Dalkmann, P., Siebe, C., Amelung, W., Schloter, M., Siemens, J.°: Does long-term irrigation with untreated
wastewater accelerate the dissipation of pharmaceuticals in soil? Environ. Sci. Technol. 48, 4963-4970
(2014)
Ding, G.-C., Radl, V., Schloter-Hai, B., Jechalke, S., Heuer, H., Smalla, K.°, Schloter, M.: Dynamics of soil
bacterial communities in response to repeated application of manure containing sulfadiazine. PLoS ONE
9:e92958 (2014)
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Fuchslueger, L. °, Kastl, E.-M. , Bauer, F., Kienzl, S., Hasibeder, R., Ladreiter-Knauss, T., Schmitt, M.,
Bahn, M., Schloter, M., Richter, A., Szukics, U.: Effects of drought on nitrogen turnover and abundances of
ammonia-oxidizers in mountain grassland. Biogeosciences 11, 6003-6015 (2014)
Gschwendtner, S., Tejedor, J., Bimueller, C., Dannenmann, M., Knabner, I.K., Schloter, M.°: Climate
change induces shifts in abundance and activity pattern of bacteria and archaea catalyzing major
transformation steps in nitrogen turnover in a soil from a Mid-European beech forest. PLoS ONE 9:e114278
(2014)
Gschwendtner, S., Leberecht, M., Engel, M., Kublik, S., Dannenmann, M., Polle, A., Schloter, M.: Effects
of elevated atmospheric CO2 on microbial community structure at the plant-soil interface of young beech
trees (Fagus sylvatica L.) grown at two sites with contrasting climatic conditions. Microb. Ecol. 69, 867-878
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Haesler, F., Hagn, A., Engel, M., Schloter, M.°: Impact of elevated atmospheric O3 on the actinobacterial
community structure and function in the rhizosphere of European beech (Fagus sylvatica L.). Front.
Microbiol. 5:36 (2014)
Kastl, E.-M., Schloter-Hai, B., Buegger, F., Schloter, M.°: Impact of fertilization on the abundance of
nitrifiers and denitrifiers at the root-soil interface of plants with different uptake strategies for nitrogen. Biol.
Fertil. Soils 51, 57-64 (2015) [published online 2014]
Legay, N.°, Baxendale, C., Grigulis, K., Krainer, U., Kastl, E.-M., Schloter, M., Bardgett, R.D., Arnoldi, C.,
Bahn, M., Dumont, M., Poly, F., Pommier, T., Clément, J.C., Lavorel, S.: Contribution of above- and
below-ground plant traits to the structure and function of grassland soil microbial communities. Ann. Bot. 114,
1011-1021 (2014)
Purahong, W.°, Hoppe, B., Kahl, T., Schloter, M., Schulze, E.-D., Bauhus, J., Buscot, F., Krüger, D.°:
Changes within a single land-use category alter microbial diversity and community structure: Molecular
evidence from wood-inhabiting fungi in forest ecosystems. J. Environ. Manage. 139, 109-119 (2014)
Purahong, W.°, Kahl, T., Schloter, M., Bauhus, J., Buscot, F., Krüger, D.: Comparing fungal richness and
community composition in coarse woody debris in Central European beech forests under three types of
management. Mycol. Prog. 13, 959-964 (2014)
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Purahong, W. °, Kapturska, D. , Pecyna, M.J. , Schulz, E., Schloter, M., Buscot, F., Hofrichter, M., Kruger,
D.: Influence of different forest system management practices on leaf litter decomposition rates, nutrient
dynamics and the activity of ligninolytic enzymes: A case study from central European forests. PLoS ONE
9:e93700 (2014)
Purahong, W., Schloter, M., Pecyna, M.J., Kapturska, D., Däumlich, V., Mital, S., Buscot, F., Hofrichter, M.,
Gutknecht, J.L.°, Krüger, D.°: Uncoupling of microbial community structure and function in decomposing litter
across beech forest ecosystems in Central Europe. Sci. Rep. 4:7014 (2014)
Radl, V.°, Chronakova, A., Cuhel, J., Simek, M., Elhottova, D., Welzl, G., Schloter, M.: Bacteria dominate
ammonia oxidation in soils used for outdoor cattle overwintering. Appl. Soil Ecol. 77, 68-71 (2014)
Regan, K.M.°, Nunan, N., Boeddinghaus, R.S., Baumgartner, V., Berner, D., Boch, S., Oelmann, Y.,
Overmann, J., Prati, D., Schloter, M., Schmitt, B., Sorkau, E., Steffens, M., Kandeler, E., Marhan, S.:
Seasonal controls on grassland microbial biogeography: Are they governed by plants, abiotic properties or
both? Soil Biol. Biochem. 71, 21-30 (2014)
Reichel, R., Radl, V., Rosendahl, I., Albert, A., Amelung, W., Schloter, M., Thiele-Bruhn, S.°: Soil microbial
community responses to antibiotic-contaminated manure under different soil moisture regimes. Appl.
Microbiol. Biotechnol. 89, 6487-6495 (2014)
page 222 of 247
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Uksa, M., Fischer, D., Welzl, G., Kautz, T., Köpke, U., Schloter, M.°: Community structure of prokaryotes
and their functional potential in subsoils is more affected by spatial heterogeneity than by temporal
variations. Soil Biol. Biochem. 75, 197-201 (2014)
Vogel, C.°, Mueller, C.W., Höschen, C., Buegger, F., Heister, K., Schulz, S., Schloter, M., Kögel-Knabner,
I.: Submicron structures provide preferential spots for carbon and nitrogen sequestration in soils. Nat.
Commun. 5:2947 (2014)
(2014)
Wallisch, S., Gril, T., Dong, X., Welzl, G., Bruns, C., Heath, E., Engel, M., Suhaldoc, M., Schloter, M.°:
Effects of different compost amendments on the abundance and composition of alkB harboring bacterial
communities in a soil under industrial use contaminated with hydrocarbons. Front. Microbiol. 5:96 (2014)
Zoennchen, C.°, Schaaf, W., Esperschütz, J.: Effect of plant litter addition on element leaching in young
sandy soils. J. Plant Nutr. Soil Sci. 177, 585-595 (2014)
page 223 of 247
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Research Unit Environmental Simulation
Ghirardo, A., Wright, L.P., Bi, Z., Rosenkranz, M., Pulido, P., Rodríguez-Concepción, M., Niinemets, U.,
Brüggemann, N., Gershenzon, J., Schnitzler, J.-P.°: Metabolic flux analysis of plastidic isoprenoid
biosynthesis in poplar leaves emitting and non-emitting isoprene. Plant Physiol. 165, 37-51 (2014)
Julkunen-Tiitto, R.°, Nenadis, N., Neugart, S., Robson, M., Agati, G., Vepsäläinen, J., Zipoli, G., Nybakken,
L., Winkler, J.B., Jansen, M.A.K.: Assessing the response of plant flavonoids to UV radiation: An overview
of appropriate techniques. Phytochem. Rev. 14, 273-297 (2015) [published online 2014]
Kreuzwieser, J.°, Scheerer, U., Kruse, J., Burzlaff, T., Honsel, A., Alfarraj, S., Georgiev, P., Schnitzler, J.-P.,
Ghirardo, A., Kreuzer, I., Hedrich, R., Rennenberg, H.: The Venus flytrap attracts insects by the release of
volatile organic compounds. J. Exp. Bot. 65, 755-766 (2014)
Loreto, F., Dicke, M., Schnitzler, J.-P., Turling, T.°: Plant volatiles and the environment. Plant Cell Environ.
37, 1905-1908 (2014)
Müller, V., Lankes, C., Albert, A., Winkler, J.B., Zimmermann, B.F., Noga, G.J., Hunsche, M.°:
Concentration of hinokinin, phenolic acids and flavonols in leaves and stems of Hydrocotyle leucocephala is
differently influenced by PAR and ecologically relevant UV-B level. J. Plant Physiol. 173, 105-115 (2015)
Penuelas, J., Asensio, D., Tholl, D., Wenke, K., Rosenkranz, M., Piechulla, B., Schnitzler, J.-P.°: Biogenic
volatile emissions from the soil. Plant Cell Environ. 37, 1866-1891 (2014)
Reichel, R., Radl, V., Rosendahl, I., Albert, A., Amelung, W., Schloter, M., Thiele-Bruhn, S.°: Soil microbial
community responses to antibiotic-contaminated manure under different soil moisture regimes. Appl.
Microbiol. Biotechnol. 89, 6487-6495 (2014)
Ritter, W., Lehmeier, C.A., Winkler, J.B., Matyssek, R., Grams, T.E.E.°: Contrasting carbon allocation
responses of juvenile European beech (Fagus sylvatica) and Norway spruce (Picea abies) to competition
and ozone. Environ. Pollut. 196, 534-543 (2015) [published online 2014]
page 224 of 247
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Research Unit Environmental Simulation
Rosenkranz, M.°, Pugh, T.A., Schnitzler, J.-P., Arneth, A.: Effect of land-use change and management on
BVOC emissions - selecting climate-smart cultivars. Plant Cell Environ. 38, 1896–1912 (2015) [published
online 2014]
(2014)
Vidovic, M., Morina, F., Milić, S., Zechmann, B., Albert, A., Winkler, J.B., Veljović Jovanović, S.°: "UV-SI"
UV-B component of sunlight stimulates photosynthesis and flavonoid accumulation in
variegated Plectranthus coleoides leaves depending on background light. Plant Cell Environ. 38, 968-979
Wright, L.P.°, Rohwer, J.M., Ghirardo, A., Hammerbacher, A., Ortiz, M., Raguschke, B., Schnitzler, J.-P.,
Gershenzon, J., Phillips, M.A.°: 1-Deoxyxylulose 5-phosphate synthase controls flux through the
2-C-methylerythritol 4-phosphate pathway in Arabidopsis thaliana. Plant Physiol. 165, 1488-1504 (2014)
page 225 of 247
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Research Unit Gene Vector
Ameres, S., Besold, K., Plachter, B., Moosmann, A.°: CD8 T cell-evasive functions of human
cytomegalovirus display pervasive MHC allele specificity, complementarity, and cooperativity. J. Immunol.
192, 5894-5905 (2014)
Baumann, U.#, Fernández-Sáiz, V.#, Rudelius, M., Lemeer, S., Rad, R., Knorn, A.M., Slawska, J., Engel, K.,
Jeremias, I., Li, Z., Tomiatti, V., Illert, A.L., Targosz, B.S., Braun, M., Perner, S., Leitges, M., Klapper, W.,
Dreyling, M., Miething, C., Lenz, G., Rosenwald, A., Peschel, C., Keller, U., Kuster, B., Bassermann, F.:
Disruption of the PRKCD-FBXO25-HAX-1 axis attenuates the apoptotic response and drives
lymphomagenesis. Nat. Med. 20, 1401-1409 (2014)
Bazot, Q., Deschamps, T., Tafforeau, L., Siouda, M., Leblanc, P., Harth-Hertle, M.L., Rabourdin-Combe, C.,
Lotteau, V., Kempkes, B., Tommasino, M., Gruffat, H., Manet, E.°: Epstein-Barr virus nuclear antigen 3A
protein regulates CDKN2B transcription via interaction with MIZ-1. Nucleic Acids Res. 42, 9700-9716 (2014)
Bussey, K., Reimer, E., Todt, H., Denker, B., Gallo, A., Konrad, A., Ottinger, M., Adler, H., Stürzl, M., Brune,
W., Brinkmann, M.M.°: The gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and murine
gammaherpesvirus 68 modulate the toll-like receptor-induced proinflammatory cytokine response. J. Virol.
88, 9245-9259 (2014)
Davari, K., Frankenberger, S., Schmidt, A., Tomi, N.S., Jungnickel, B.°: Checkpoint kinase 2 is required for
efficient immunoglobulin diversification. Cell Cycle 13, 3659-3669 (2014)
Fiebiger, B.M., Pfister, H., Behrends, U., Mautner, J.°: Polyubiquitination of lysine-48 is an essential but
indirect signal for MHC Class I antigen processing. Eur. J. Immunol. 45, 716-727 (2014)
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Frankenberger, S. , Davari, K. , Fischer-Burkart, S., Böttcher, K., Tomi, N.S., Zimber-Strobl, U.,
Jungnickel, B.°: Checkpoint kinase 1 negatively regulates somatic hypermutation. Nucleic Acids Res. 42,
3666-3674 (2014)
Gabaev, I., Elbasani, E., Ameres, S., Steinbrück, L., Stanton, R., Döring, M., Lenac Rovis, T., Kalinke, U.,
Jonjic, S., Moosmann, A., Messerle, M.°: Expression of the human cytomegalovirus UL11 glycoprotein in
viral infection and evaluation of its effect on virus-epecific CD8 T cells. J. Virol. 88, 14326-14339 (2014)
Ghasemi, A., Jeddi-Tehrani, M.°, Mautner, J., Salari, M.H., Zarnani, A.H.°: Immunization of mice with a
novel recombinant molecular chaperon confers protection against Brucella melitensis infection. Vaccine 32,
6659-6666 (2014)
Hojer, C., Frankenberger, S., Strobl, L.J., Feicht, S., Djermanovic, K., Jagdhuber, F., Hömig-Hölzel, C.,
Ferch, U., Ruland, J., Rajewsky, K., Zimber-Strobl, U.°: B cell expansion and lymphomagenesis induced by
chronic CD40 signaling is strictly dependent on CD19. Cancer Res. 74, 4318-4328 (2014)
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Kim, D.K., Lee, J., Kim, S.R., Choi, D.S., Yoon, Y.J., Kim, J.H., Go, G., Nhung, D., Hong, K., Jang, S.C.,
Kim, S.H., Park, K.S., Kim, O.Y., Park, H.T., Seo, J.H., Aikawa, E., Baj-Krzyworzeka, M., van Balkom, B.W.,
Belting, M., Blanc, L., Bond, V., Bongiovanni, A., Borràs, F.E., Buée, L., Buzás, E.I., Cheng, L., Clayton, A.,
Cocucci, E., Dela Cruz, C.S., Desiderio, D.M., di Vizio, D., Ekström, K., Falcón-Pérez, J.M., Gardiner, C.,
Giebel, B., Greening, D.W., Gross, J.C., Gupta, D., Hendrix, A., Hill, A.F., Hill, M.M., Nolte-'t Hoen, E.,
Hwang, D.W., Inal, J., Jagannadham, M.V., Jayachandran, M., Jee, Y.K., Jørgensen, M., Kim, K.P., Kim,
Y.K., Kislinger, T., Lässer, C., Lee, D.S., Lee, H., van Leeuwen, J., Lener, T., Liu, M.L., Lötvall, J., Marcilla,
A., Mathivanan, S., Möller, A., Morhayim, J., Mullier, F., Nazarenko, I., Nieuwland, R., Nunes, D.N., Pang,
K., Park, J., Patel, T., Pocsfalvi, G., del Portillo, H., Putz, U., Ramirez, M.I., Rodrigues, M.L., Roh, T.Y.,
Royo, F., Sahoo, S., Schiffelers, R., Sharma, S., Siljander, P., Simpson, R.J., Soekmadji, C., Stahl, P.,
Stensballe, A., Stępień, E., Tahara, H., Trummer, A., Valadi, H., Vella, L.J., Wai, S.N., Witwer, K., Yáñez-Mó,
M., Youn, H., Zeidler, R., Gho, Y.S.°: EVpedia: A community web portal for extracellular vesicles research.
Bioinformatics 31, 933-939 (2015) [published online 2014]
Kulic, I., Robertson, G., Chang, L., Baker, J.H., Lockwood, W.W., Mok, W., Fuller, M., Fournier, M., Wong,
N., Chou, V., Robinson, M.D., Chun, H.J., Gilks, B., Kempkes, B., Thomson, T.A., Hirst, M., Minchinton, A.I.,
Lam, W.L., Jones, S., Marra, M., Karsan, A.°: Loss of the Notch effector RBPJ promotes tumorigenesis. J.
Exp. Med. 212, 37-52 (2015) [published online 2014]
Lehnert, C., Weiswange, M., Jeremias, I., Bayer, C., Grunert, M., Debatin, K.M., Strauss, G.P.°:
TRAIL-receptor costimulation inhibits proximal TCR signaling and suppresses human T cell activation and
proliferation. J. Immunol. 193, 4021-4031 (2014)
Linnerbauer, S., Behrends, U., Adhikary, D., Witter, K., Bornkamm, G.W., Mautner, J.°: Virus and
autoantigen-specific CD4+ T cells are key effectors in a SCID mouse model of EBV-associated
post-transplant lymphoproliferative disorders. PLoS Pathog. 10:e1004068 (2014)
Maetzig, T., Kuehle, J., Schwarzer, A., Turan, S., Rothe, M., Chaturvedi, A., Morgan, M., Ha, T.C., Heuser,
M., Hammerschmidt, W., Baum, C., Schambach, A.°: All-in-One inducible lentiviral vector systems based
on drug controlled FLP recombinase. Biomaterials 35, 4345-4356 (2014)
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Mohr, C.F. , Kalmer, M.A. , Gross, C., Mann, M.C., Sterz, K., Kieser, A., Fleckenstein, B.W., Kress, A.K.°:
The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in
lymphocytes and contributes to their invasive migration. Cell Commun. Signal. 12:46 (2014)
page 227 of 247
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joint first authors
Tomi, N.S., Davari, K., Grotzky, D., Loos, F., Böttcher, K., Frankenberger, S., Jungnickel, B.°: Analysis of
SHPRH functions in DNA repair and immunoglobulin diversification. DNA Repair 24, 63-72 (2014)
Weller, P., Bankfalvi, A., Gu, X., Dominas, N., Lehnerdt, G.F., Zeidler, R., Lang, S., Brandau, S., Dumitru,
C.A.°: The role of tumour FoxP3 as prognostic marker in different subtypes of head and neck cancer. Eur. J.
Cancer 50, 1291-1300 (2014)
Yabal, M., Müller, N., Adler, H., Knies, N., Groß, C.J., Damgaard, R.B., Kanegane, H., Ringelhan, M.,
Kaufmann, T., Heikenwälder, M., Strasser, A., Groß, O., Ruland, J., Peschel, C., Gyrd-Hansen, M., Jost,
P.J.°: XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation. Cell Rep. 7,
1796-1808 (2014)
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Research Unit Medical Radiation Physics and Diagnostics
Braun, C., Schlattl, H., Tischenko, O., Dietrich, O., Hoeschen, C.°: Development and evaluation of a novel
designed breast CT system. Proc. SPIE 9033:903311 (2014)
Brudecki, K.°, Li, W.B.°, Meisenberg, O., Tschiersch, J., Hoeschen, C., Oeh, U.: Age-dependent
inhalation doses to members of the public from indoor short-lived radon progeny. Radiat. Environ. Biophys.
53, 535-549 (2014)
Discher, M.°, Greiter, M.B., Woda, C.: Photon energy dependence and angular response of glass display
used in mobile phones for accident dosimetry. Radiat. Meas. 71, 471-474 (2014)
Kastl, M., Giussani, A.°, Blanchardon, E., Breustedt, B., Fritsch, P., Hoeschen, C., López, M.A.: Developing
a physiologically based approach for modeling plutonium decorporation therapy with DTPA. Int. J. Radiat.
Biol. 90, 1062-1067 (2014)
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Li, W.B.°, Müllner, M., Greiter, M.B., Bissardon, C., Xie, W.Z., Schlattl, H., Oeh, U., Li, J.L., Hoeschen,
C.: Monte Carlo simulations of dose enhancement around gold nanoparticles used as X-ray imaging contrast
agents and radiosensitizers. Proc. SPIE 9033:90331K (2014)
McMillan, K.L.°, Bostani, M., Cagnon, C.H., Zankl, M., Sepahdari, A.R., McNitt-Gray, M.F.: Size-specific,
scanner-independent organ dose estimates in contiguous axial and helical head CT examinations. Med.
Phys. 41:121909 (2014)
Müller, B.H., Hoeschen, C., Grüner, F.J., Johnson, T.R.C.°: X-ray fluorescence molecular imaging of high-Z
tracers: Investigation of a novel analyzer based setup. Proc. SPIE 9033:90331J (2014)
Müllner, M., Schlattl, H., Oeh, U., Hoeschen, C., Dietrich, O.°: Feasibility study of spectral Computed
Tomography (CT) with gold as a new contrast agent. Proc. SPIE 9033:90334A (2014)
Petoussi-Henß, N., Becker, J., Greiter, M.B., Schlattl, H., Zankl, M., Hoeschen, C.°: Construction of
anthropomorphic hybrid, dual-lattice voxel models for optimizing image quality and dose in radiography.
Proc. SPIE 9033:90331W (2014)
Petoussi-Henß, N.°, Bolch, W.E., Eckerman, K.F., Endo, A., Hertel, N., Hunt, J., Menzel, H.G., Pelliccioni,
M., Schlattl, H., Zankl, M.: The first ICRP/ICRU application of the male and female adult reference
computational phantoms. Phys. Med. Biol. 59, 5209-5224 (2014)
Saito, K.°, Petoussi-Henß, N.: Ambient dose equivalent conversion coefficients for radionuclides
exponentially distributed in the ground. J. Nucl. Sci. Technol. 51, 1274-1287 (2014)
Seidenbusch, M.°, Harder, D., Regulla, D.F.: Systematic survey of the dose enhancement in
tissue-equivalent materials facing medium- and high-Z backscatterers exposed to X-rays with energies from
5 to 250 keV. Radiat. Environ. Biophys. 53, 437-453 (2014)
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Research Unit Medical Radiation Physics and Diagnostics
Seidenbusch, M.C.°, Harder, D., Regulla, D.F., Schneider, K.°: Conversion factors for determining organ
doses received by paediatric patients in high-resolution single slice computed tomography with narrow
collimation. Z. Med. Phys. 24, 123-137 (2014)
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Research Unit Microbe-Plant Interactions
®
Bartha, B.°, Huber, C.A.°, Schröder, P.°: Uptake and metabolism of diclofenac in Typha latifolia - how
plants cope with human pharmaceutical pollution. Plant Sci. 227, 12-20 (2014)
6373-6383 (2014)
Budiharjo, A.#, Chowdhury, S.P.#, Dietel, K., Beator, B., Dolgova, O., Fan, B., Bleiss, W., Ziegler, J.T.,
Schmid, M., Hartmann, A., Borriss, R.°: Transposon mutagenesis of the plant-associated Bacillus
amyloliquefaciens ssp. plantarum FZB42 revealed that the nfrA and RBAM17410 genes are involved in
plant-microbe-interactions. PLoS ONE 9:e98267 (2014)
Cui, H., Wang, S.-P.°, Fu, J., Zhou, Z.-Q., Zhang, N., Guo, L.: Influence of ciprofloxacin on microbial
community structure and function in soils. Biol. Fertil. Soils 50, 939-947 (2014)
Hartmann, A., Rothballer, M., Hense, B.A., Schröder, P.: Bacterial quorum sensing compounds are
important modulators of microbe-plant interactions. Front. Plant Sci. 5:131 (2014)
Kröber, M., Wibberg, D., Grosch, R., Eikmeyer, F., Verwaaijen, B., Chowdhury, S.P., Hartmann, A., Pühler,
A., Schlüter, A.°: Effect of the strain Bacillus amyloliquefaciens FZB42 on the microbial community in the
rhizosphere of lettuce under field conditions analyzed by whole metagenome sequencing. Front. Microbiol.
5:252 (2014)
Macherius, A., Seiwert, B., Schröder, P., Huber, C.A., Lorenz, W., Reemtsma, T.°: Identification of plant
metabolites of environmental contaminants by UPLC-QToF-MS: The in vitro metabolism of triclosan in
horseradish. J. Agric. Food Chem. 62, 1001-1009 (2014)
Montero-Calasanz, M.D.°, Göker, M., Rohde, M., Spröer, C., Schumann, P., Busse, H.J., Schmid, M., Klenk,
H.P., Tindall, B.J.°, Camacho, M.: Chryseobacterium oleae sp. nov., an efficient plant growth promoting
bacterium in the rooting induction of olive tree (Olea europaea L.) cuttings and emended descriptions of the
genus Chryseobacterium, C. daecheongense, C. gambrini, C. gleum, C. joostei, C. jejuense, C. luteum, C.
shigense, C. taiwanense, C. ureilyticum and C. vrystaatense. Syst. Appl. Microbiol. 37, 342-350 (2014)
page 231 of 247
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Research Unit Microbe-Plant Interactions
Nabti, E., Bensidhoum, L., Tabli, N., Dahel, D., Weiss, A., Rothballer, M., Schmid, M., Hartmann, A.°:
Growth stimulation of barley and biocontrol effect on plant pathogenic fungi by a Cellulosimicrobium sp.
strain isolated from salt-affected rhizosphere soil in northwestern Algeria. Eur. J. Soil Biol. 61, 20-26 (2014)
Oufdou, K.°, Benidire, L.°, Lyubenova, L.°, Daoui, K.°, El Abidine Fatemi, Z.°, Schröder, P.°: Enzymes of
the glutathione-ascorbate cycle in leaves and roots of rhizobia-inoculated faba bean plants (Vicia faba L.)
under salinity stress. Eur. J. Soil Biol. 60, 98-103 (2014)
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Seubert, B. , Grünwald, B. , Kobuch, J. , Cui, H. , Schelter, F., Schaten, S., Siveke, J.T., Lim, N.H., Nagase,
H., Simonavicius, N., Heikenwälder, M., Reinheckel, T., Sleeman, J.P., Janssen, K.P., Knolle, P.A.,
Krüger, A.°: TIMP-1 creates a pre-metastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil
recruitment in mice. Hepatology 61, 238-248 (2015) [published online 2014]
(2014)
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Research Unit Molecular Exposomics
Altschuh, J.°, Lenoir, D., Rehfeldt, F., Brüggemann, R.: Applicability domain of nonlinear property-property
relationships - example: Estimation of vapour pressure. Match-Commun. Math. Comput. Chem. 73, 303-326
(2015)
Brüggemann, R.°, Scherb, H., Schramm, K.-W., Cok, I., Voigt, K.: CombiSimilarity, an innovative method to
compare environmental and health data sets with different attribute sizes example: Eighteen organochlorine
pesticides in soil and human breast milk samples. Ecotoxicol. Environ. Saf. 105, 29-35 (2014)
Deyerling, D.°, Wang, J., Hu, W., Westrich, B., Peng, C., Bi, Y., Henkelmann, B., Schramm, K.-W.: PAH
distribution and mass fluxes in the Three Gorges Reservoir after impoundment of the Three Gorges Dam.
Sci. Total Environ. 491-492, 123-130 (2014)
Ehret, J.°, Vijver, M., Peijnenburg, W.: The application of QSAR approaches to nanoparticles. ATLA-Altern.
Lab. Anim. 42, 43-50 (2014)
Gajewska, M.°, Paini, A., Sala Benito, J.V., Burton, J., Worth, A.P., Urani, C., Briesen, H., Schramm, K.-W.:
In vitro-to-in vivo correlation of the skin penetration, liver clearance and hepatotoxicity of caffeine. Food
Chem. Toxicol. 75, 39-49 (2015)
Gajewska, M.°, Worth, A., Urani, C., Briesen, H., Schramm, K.-W.: Application of physiologically-based
toxicokinetic modelling in oral-to-dermal extrapolation of threshold doses of cosmetic ingredients. Toxicol.
Lett. 227, 189-202 (2014)
Gajewska, M.°, Worth, A., Urani, C., Briesen, H., Schramm, K.-W.: The acute effects of daily nicotine intake
on heart rate - a toxicokinetic and toxicodynamic modelling study. Regul. Toxiol. Pharmacol. 70, 312-324
(2014)
Galvao, P.°, Henkelmann, B., Longo, R., Dorneles, P.R., Torres, J.P., Malm, O., Schramm, K.-W.: Partition
of organochlorine concentrations among suspended solids, sediments and brown mussel Perna perna, in
tropical bays. Chemosphere 114, 9-15 (2014)
Jakobi, G.°, Kirchner, M., Henkelmann, B., Körner, W., Offenthaler, I., Moche, W., Weiß, P.S., Schaub, M.,
Schramm, K.-W.: Atmospheric bulk deposition measurements of organochlorine pesticides at three alpine
summits. Atmos. Environ. 101, 158-165 (2015)
Katchy, A.#, Pinto, C.#, Jonsson, P., Nguyen-Vu, T., Pandelova, M., Riu, A., Schramm, K.-W., Samarov, D.,
Gustafsson, J.-A., Bondesson, M., Williams, C.°: Coexposure to phytoestrogens and bisphenol a mimics
estrogenic effects in an additive manner. Toxicol. Sci. 138, 21-35 (2014)
Levy, W.°, Brena, B.M.°, Henkelmann, B., Bernhöft, S., Pirez, M., González-Sapienza, G.°, Schramm,
K.-W.°: Screening of dioxin-like compounds by complementary evaluation strategy utilising ELISA,
micro-EROD, and HRGC-HRMS in soil and sediments from Montevideo, Uruguay. Toxicol. Vitro 28,
1036-1045 (2014)
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Mahugija, J.A.°, Henkelmann, B., Schramm, K.-W.: Levels and patterns of organochlorine pesticides and
their degradation products in rainwater in Kibaha Coast Region, Tanzania. Chemosphere 118, 12-19 (2015)
Mahugija, J.A.°, Henkelmann, B., Schramm, K.-W.: Levels, compositions and distributions of
organochlorine pesticide residues in soil 5-14 years after clean-up of former storage sites in Tanzania.
Chemosphere 117, 330-337 (2014)
Mumbo, J., Henkelmann, B., Abdelaziz, A., Pfister, G., Nguyen, N., Schroll, R., Munch, J.-C., Schramm,
K.-W.°: Persistence and dioxin-like toxicity of carbazole and chlorocarbazoles in soil. Environ. Sci. Pollut.
Res. 22, 1344-1356 (2015) [published online 2014]
Okay, O.S.°, Karacik, B., Güngördü, A., Ozmen, M., Yilmaz, A., Koyunbaba, N.C., Yakan, S.D., Korkmaz, V.,
Henkelmann, B., Schramm, K.-W.: Micro-organic pollutants and biological response of mussels in marinas
and ship building/breaking yards in Turkey. Sci. Total Environ. 496, 165-178 (2014)
Omwoma, S.°, Owuor, P.O., Ongeri, D.M.K., Umani, M., Lalah, J.O., Schramm, K.-W.: Declining commercial
fish catches in Lake Victoria's Winam Gulf: The importance of restructuring Kenya's aquaculture programme.
Lakes & Reservoirs 19, 206-210 (2014)
Omwoma, S., Lalah, J.O.°, Virani, M., Schramm, K.-W., Henkelmann, B.: Dioxin-like PCBs and PCDD/Fs in
surface sediments near the shore of Winam Gulf, Lake Victoria. Chemosphere 118, 143-147 (2014)
Omwoma, S., Lalah, J.O.°, Ongeri, D.M.K., Schramm, K.-W.: The impact of agronomic inputs on selected
physicochemical features and their relationships with heavy metals levels in surface sediment and water in
sugarcane farms in Nzoia, Kenya. Environ. Earth Sci. 71, 4297-4308 (2014)
Otieno, P.O.°, Okinda Owuor, P., Lalah, J.O., Pfister, G., Schramm, K.-W.: Monitoring the occurrence and
distribution of selected organophosphates and carbamate pesticide residues in the ecosystem of Lake
Naivasha, Kenya. Toxicol. Environ. Chem. 97, 51-61 (2015) [published online 2014]
Quick, M., Berndt, F., Dobryakov, A.L., Ioffe, I.N., Granovsky, A.A., Knie, C., Mahrwald, R., Lenoir, D.,
Ernsting, N.P.°, Kovalenko, S.A.°: Photoisomerization dynamics of stiff-stilbene in solution. J. Phys. Chem. B
118, 1389-1402 (2014)
Rathore, R.°, Schramm, K.-W.: Ethoxyresorufin-O-Deethylase (EROD) activity modulation of
2,3,7,8-tetrachlorodibenzo-p-dioxin and 3,3',4,4',5-pentachlorobiphenyl (PCB 126) in the presence of
aqueous suspensions of nano-C60. ATLA-Altern. Lab. Anim. 42, 71-80 (2014)
Shen, H.°, Xu, W., Peng, S., Scherb, H., She, J., Voigt, K., Alamdar, A., Schramm, K.-W.°: Pooling
samples for "top-down" molecular exposomics research: The methodology. Environ. Health 13:8 (2014)
Wang, J.°, Song, G., Li, A., Henkelmann, B., Pfister, G., Tong, A.Z., Schramm, K.-W.°: Combined
chemical and toxicological long-term monitoring for AhR agonists with SPMD-based virtual organisms in
drinking water Danjiangkou Reservoir, China. Chemosphere 108, 306-313 (2014)
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Wang, J.°, Bernhöft, S., Pfister, G., Schramm, K.-W.°: Water exposure assessment of aryl hydrocarbon
receptor agonists in Three Gorges Reservoir, China using SPMD-based virtual organisms. Sci. Total
Environ. 496, 26-34 (2014)
Yilmaz, A., Karacik, B., Henkelmann, B., Pfister, G., Schramm, K.-W., Yakan, S.D., Barlas, B.°, Okay,
O.S.°: Use of passive samplers in pollution monitoring: A numerical approach for marinas. Environ. Int. 73,
85-93 (2014)
Zhu, N., Schramm, K.-W., Wang, T., Henkelmann, B., Zheng, X., Fu, J., Gao, Y., Wang, Y.°, Jiang, G.:
Environmental fate and behavior of persistent organic pollutants in Shergyla Mountain, southeast of the
Tibetan Plateau of China. Environ. Pollut. 191, 166-174 (2014)
Zhu, X.°, Shi, T., Henkelmann, B., Pfister, G., Wang, W., Mu, J., Schramm, K.-W.°: Monitoring of
organochlorine pesticides in the urban air of Dalian, China with semipermeable membrane devices. Chin.
Sci. Bull. 59, 2957-2965 (2014)
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Research Unit Plant Genome and Systems Biology
Banaei-Moghaddam, A.M., Martis, M.M., Macas, J., Gundlach, H., Himmelbach, A., Altschmied, L., Mayer,
K.F.X., Houben, A.°: Genes on B chromosomes: Old questions revisited with new tools. Biochim. Biophys.
Acta-Gene Regul. Mech. 1849, 64-70 (2014)
Behringer, C., Bastakis, E., Ranftl, Q., Mayer, K.F.X., Schwechheimer, C.°: Functional diversification within
the family of B-GATA transcription factors through the LLM-domain. Plant Physiol. 166, 293-305 (2014)
Chaki, M., Kovacs, I., Spannagl, M., Lindermayr, C.°: Computational prediction of candidate proteins for
S-nitrosylation in Arabidopsis thaliana. PLoS ONE 9:e110232 (2014)
Choulet, F.°, Alberti, A., Theil, S., Glover, N., Barbe, V., Daron, J., Pingault, L., Sourdille, P., Couloux, A.,
Paux, E., Leroy, P., Mangenot, S., Guilhot, N., Le Gouis, J., Balfourier, F., Alaux, M., Jamilloux, V., Poulain,
J., Durand, C., Bellec, A., Gaspin, C., Safar, J., Dolezel, J., Rogers, J., Vandepoele, K., Aury, J.M., Mayer,
K.F.X., Bergès, H., Quesneville, H., Wincker, P., Feuillet, C.°: Structural and functional partitioning of bread
wheat chromosome 3B. Science 345:1249721 (2014)
Demko, V., Perroud, P.F., Johansen, W., Delwiche, C.F., Cooper, E.D., Remme, P., Ako, A.E., Kugler, K.G.,
Mayer, K.F.X., Quatrano, R.S., Olsen, O.A.°: Genetic analysis of DEK1 loop function in three-dimensional
body patterning in physcomitrella patens. Plant Physiol. 166, 903-919 (2014)
Dey, S., Wenig, M., Langen, G., Sharma, S., Kugler, K.G., Knappe, C., Hause, B., Bichlmeier, M.,
Babaeizad, V., Imani, J., Janzik, I., Stempfl, T., Hueckelhoven, R., Kogel, K.H., Mayer, K.F.X., Vlot, A.C.°:
Bacteria-triggered systemic immunity in barley appears to be associated with WRKY and ETHYLENE
RESPONSIVE FACTORs but not with salicylic acid. Plant Physiol. 166, 2133-2151 (2014)
Gläßer, C., Haberer, G., Finkemeier, I., Pfannschmidt, T., Kleine, T., Leister, D., Dietz, K.J., Häusler, R.E.,
Grimm, B., Mayer, K.F.X.°: Meta-analysis of retrograde signaling in Arabidopsis thaliana reveals a core
module of genes embedded in complex cellular signaling networks. Mol. Plant 7, 1167-1190 (2014)
Guo, H., Wang, X., Gundlach, H., Mayer, K.F.X., Peterson, D.G., Scheffler, B.E., Chee, P.W., Paterson,
A.H.°: Extensive and biased intergenomic non-reciprocal DNA exchanges shaped a nascent polyploid
genome, Gossypium (cotton). Genetics 197, 1153-1163 (2014)
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International Wheat Genome Sequencing Consortium, Mayer, K.F.X.°, Rogers, J., Dolezel, J., Pozniak, C.,
Eversole, K., Feuillet, C., Gill, B., Friebe, B., Lukaszewski, A.J., Sourdille, P., Endo, T.R., Kubaláková, M.,
Cihalikova, J., Dubska, Z., Vrana, J., Sperkova, R., Simková, H., Febrer, M., Clissold, L., McLay, K., Singh,
K., Chhuneja, P., Singh, N.K., Khurana, J.P., Akhunov, E.D., Choulet, F., Alberti, A., Barbe, V., Wincker, P.,
Kanamori, H., Kobayashi, F., Itoh, T., Matsumoto, T., Sakai, H., Tanaka, T., Wu, J., Ogihara, Y., Handa, H.,
Maclachlan, P.R., Sharpe, A., Klassen, D., Edwards, D., Batley, J., Olsen, O.A., Sandve, S.R., Lien, S.,
Steuernagel, B., Wulff, B., Caccamo, M., Ayling, S., Ramirez-Gonzalez, R.H., Clavijo, B.J., Wright, J.,
Pfeifer, M., Spannagl, M., Martis, M.M., Mascher, M., Chapman, J., Poland, J.A., Scholz, U., Barry, K.,
Waugh, R., Rokhsar, D.S., Muehlbauer, G.J., Stein, N., Gundlach, H., Zytnicki, M., Jamilloux, V.,
Quesneville, H., Wicker, T., Faccioli, P., Colaiacovo, M., Stanca, A.M., Budak, H., Cattivelli, L., Glover, N.,
Pingault, L., Paux, E., Sharma, S., Appels, R., Bellgard, M., Chapman, B., Nussbaumer, T., Bader, K.C.,
Rimbert, H., Wang, S., Knox, R., Kilian, A., Alaux, M., Alfama, F., Couderc, L., Guilhot, N., Viseux, C., Loaec,
M., Keller, B., Praud, S.: A chromosome-based draft sequence of the hexaploid bread wheat (Triticum
aestivum) genome. Science 345:1251788 (2014)
Keilwagen, J., Kilian, B.°, Özkan, H., Babben, S., Perovic, D., Mayer, K.F.X., Walther, A., Poskar, C.H.,
Ordon, F., Eversole, K., Börner, A., Ganal, M., Knüpffer, H., Graner, A., Friedel, S.: Separating the wheat
from the chaff - a strategy to utilize plant genetic resources from ex situ genebanks. Sci. Rep. 4:5231 (2014)
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Marcussen, T. , Sandve, S.R. °, Heier, L., Spannagl, M., Pfeifer, M., International Wheat Genome
Sequencing Consortium, Jakobsen, K.S., Wulff, B.B., Steuernagel, B., Mayer, K.F.X., Olsen, O.A.: Ancient
hybridizations among the ancestral genomes of bread wheat. Science 345:1250092 (2014)
Mathew, L. S., Spannagl, M., Al-Malki, A., George, B., Torres, M.F., Al-Dous, E. K., Al-Azwani, E. K.,
Hussein, E., Mathew, S., Mayer, K.F.X., Mohamoud, Y. A., Suhre, K., Malek, J. A.°: A first genetic map of
date palm (Phoenix dactylifera) reveals long-range genome structure conservation in the palms. BMC
Genomics 15:285 (2014)
Nussbaumer, T., Kugler, K.G., Schweiger, W., Bader, K.C., Gundlach, H., Spannagl, M., Poursarebani,
N., Pfeifer, M., Mayer, K.F.X.°: chromoWIZ: A web tool to query and visualize chromosome-anchored genes
from cereal and model genomes. BMC Plant Biol. 14:348 (2014)
Nussbaumer, T., Kugler, K.G., Bader, K.C., Sharma, S., Seidel, M., Mayer, K.F.X.°:
RNASeqExpressionBrowser - a web interface to browse and visualize high-throughput expression data.
#
#
Pfeifer, M. , Kugler, K.G. , Sandve, S.R., Zhan, B., Rudi, H., Hvidsten, T.R., International Wheat Genome
Sequencing Consortium, Mayer, K.F.X., Olsen, O.A.°: Genome interplay in the grain transcriptome of
hexaploid bread wheat. Science 345:1250091 (2014)
Poursarebani, N.#, Nussbaumer, T.#, Simková, H., Safar, J., Witsenboer, H., van Oeveren, J., International
Wheat Genome Sequencing Consortium (Schnurbusch, T.°), Dolezel, J., Mayer, K.F.X., Stein, N.: Whole
Genome Profiling (WGP™) and shotgun sequencing delivers an anchored, gene-decorated, physical map
assembly of bread wheat chromosome 6A. Plant J. 79, 334-347 (2014)
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joint first authors
Schlicke, H., Hartwig, A.S., Firtzlaff, V., Richter, A.S., Glässer, C., Mayer, K.F.X., Finkemeier, I., Grimm, B.°:
Induced deactivation of genes encoding chlorophyll biosynthesis enzymes disentangles
tetrapyrrole-mediated retrograde signalling. Mol. Plant 7, 1211-1227 (2014)
Tang, H., Krishnakumar, V., Bidwell, S., Rosen, B., Chan, A., Zhou, S., Gentzbittel, L., Childs, K.L., Yandell,
M.D., Gundlach, H., Mayer, K.F.X., Schwartz, D.C., Town, C.D.°: An improved genome release (version
Mt4.0) for the model legume Medicago truncatula. BMC Genomics 15:312 (2014)
Unterseer, S., Bauer, E., Haberer, G., Seidel, M., Knaak, C., Ouzunova, M., Meitinger, T., Strom, T.M.,
Fries, R., Pausch, H., Bertani, C., Davassi, A., Mayer, K.F.X., Schön, C.C.°: A powerful tool for genome
analysis in maize: Development and evaluation of the high density 600k SNP genotyping array. BMC
Genomics 15:823 (2014)
Wang, M.#, Yu, Y.#, Haberer, G.#, Marri, P.R.#, Fan, C., Goicoechea, J.L., Zuccolo, A., Song, X., Kudrna, D.,
Ammiraju, J.S., Cossu, R.M., Maldonado, C., Chen, J., Lee, S., Sisneros, N., de Baynast, K., Golser, W.,
Wissotski, M., Kim, W.J., Sanchez, P., Ndjiondjop, M.N., Sanni, K., Long, M., Carney, J., Panaud, O.,
Wicker, T., Machado, C.A., Chen, M.°, Mayer, K.F.X.°, Rounsley, S.°, Wing, R.A.°: The genome sequence of
African rice (Oryza glaberrima) and evidence for independent domestication. Nat. Genet. 46, 982-988 (2014)
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Wang, W. , Haberer, G. , Gundlach, H., Gläßer, C., Nussbaumer, T., Luo, M.C., Lomsadze, A.,
Borodovsky, M., Kerstetter, R.A., Shanklin, J., Byrant, D.W., Mockler, T.C., Appenroth, K.J., Grimwood, J.,
Jenkins, J., Chow, J., Choi, C., Adam, C., Cao, X.H., Fuchs, J., Schubert, I., Rokhsar, D., Schmutz, J.,
Michael, T.P., Mayer, K.F.X., Messing, J.°: The Spirodela polyrhiza genome reveals insights into its
neotenous reduction fast growth and aquatic lifestyle. Nat. Commun. 5:3311 (2014)
Weßling, R., Epple, P., Altmann, S., He, Y., Yang, L., Henz, S.R., McDonald, N., Wiley, K., Bader, K.C.,
Gläßer, C., Mukhtar, M.S., Haigis, S., Ghamsari, L., Stephens, A.E., Ecker, J.R., Vidal, M., Jones, J.D.,
Mayer, K.F.X., ver Loren van Themaat, E., Weigel, D., Schulze-Lefert, P., Dangl, J.L.°, Panstruga, R.°,
Braun, P.°: Convergent targeting of a common host protein-network by pathogen effectors from three
kingdoms of life. Cell Host Microbe 16, 364-375 (2014)
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joint first authors
Research Unit Protein Science
Bakshi, M.V., Azimzadeh, O., Barjaktarovic, Z., Kempf, S.J., Merl-Pham, J., Hauck, S.M., Buratovic, S.,
Eriksson, P., Atkinson, M.J., Tapio, S.°: Total body exposure to low-dose ionizing radiation induces
long-term alterations to the liver proteome of neonatally exposed mice. J. Proteome Res. 14, 366-373 (2015)
Becirovic, E.#, Nguyen, O.N.#, Paparizos, C., Butz, E.S., Stern-Schneider, G., Wolfrum, U., Hauck, S.M.,
Ueffing, M., Wahl-Schott, C., Michalakis, S., Biel, M.°: Peripherin-2 couples rhodopsin to the CNG channel
in outer segments of rod photoreceptors. Hum. Mol. Genet. 23, 5989-5997 (2014)
Boldt, K.°, Gloeckner, C.J., Texier, Y., von Zweydorf, F., Ueffing, M.°: Applying SILAC for the differential
analysis of protein complexes. Methods Mol. Biol. 1188, 177-190 (2014)
Breitenbach, H.H.#, Wenig, M.#, Wittek, F., Jordá, L., Maldonado-Alconada, A.M., Sarioglu, H., Colby,
T.V., Knappe, C., Bichlmeier, M., Pabst, E., Mackey, D.M., Parker, J.E., Vlot, A.C.°: Contrasting roles of
the apoplastic aspartyl protease APOPLASTIC, ENHANCED DISEASE SUSCEPTIBILITY1-DEPENDENT1
and LEGUME LECTIN-LIKE PROTEIN1 in arabidopsis systemic acquired resistance. Plant Physiol. 165,
791-809 (2014)
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Cevik, S. , Sanders, A.A.W.M. , van Wijk, E. , Boldt, K. , Clarke, L., van Reeuwijk, J., Hori, Y., Horn, N.,
Hetterschijt, L., Wdowicz, A., Mullins, A., Kida, K., Kaplan, O.I., van Beersum, S.E.C., Wu, K.M., Letteboer,
S.J.F., Mans, D.A., Katada, T., Kontani, K., Ueffing, M., Roepman, R., Kremer, H., Blacque, O.E.°: Active
transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary
membrane subdomain. PLoS Genet. 9:e1003977 (2013)
(2014)
Degroote, R.L., Hauck, S.M., Amann, B., Hirmer, S., Ueffing, M., Deeg, C.A.°: Unraveling the equine
lymphocyte proteome: Differential septin 7 expression associates with immune cells in equine recurrent
uveitis. PLoS ONE 9:e91684 (2014)
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joint first authors
Grabe, H.J.°, Assel, H., Bahls, T.A., Dörr, M., Endlich, K.H., Endlich, N., Erdmann, P., Ewert, R., Felix, S.B.,
Fiene, B., Fischer, T., Fleßa, S., Friedrich, N., Gadebusch-Bondio, M., Salazar, M.G., Hammer, E., Haring,
R., Havemann, C., Hecker, M., Hoffmann, W.J., Holtfreter, B., Kacprowski, T., Klein, K., Kocher, T.M., Kock,
H., Krafczyk, J., Kuhn, J., Langanke, M., Lendeckel, U., Lerch, M.M., Lieb, W., Lorbeer, R., Mayerle, J.,
Meissner, K., Meyer zu Schwabedissen, H.E., Nauck, M.A., Ott, K., Rathmann, W.G., Rettig, R., Richardt,
C., Saljé, K., Schminke, U., Schulz, A., Schwab, M., Siegmund, W., Stracke, S., Suhre, K., Ueffing, M.,
Ungerer, S., Völker, U., Völzke, H., Wallaschofski, H., Werner, V., Zygmunt, M.T., Kroemer, H.K.: Cohort
profile: Greifswald approach to individualized medicine (GANI_MED). J. Transl. Med. 12:144 (2014)
Griciuc, A., Roux, M.J., Merl, J., Giangrande, A., Hauck, S.M., Aron, L.°, Ueffing, M.°: Proteomic survey
reveals altered energetic patterns and metabolic failure prior to retinal degeneration. J. Neurosci. 34,
2797-2812 (2014)
Hauck, S.M.°, von Toerne, C., Ueffing, M.: The neuroprotective potential of retinal Müller glial cells. Adv.
Exp. Med. Biol. 801, 381-387 (2014)
Heim, A.#, Grimm, C.#, Müller, U., Häußler, S., Mackeen, M.M., Merl, J., Hauck, S.M., Kessler, B.M.,
Schofield, C.J., Wolf, A.°, Böttger, A.°: Jumonji domain containing protein 6 (Jmjd6) modulates splicing and
specifically interacts with arginine-serine-rich (RS) domains of SR- and SR-like proteins. Nucleic Acids Res.
42, 7833-7850 (2014)
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Kempf, S.J., Buratovic, S., von Toerne, C., Mörtl, S., Stenerlöw, B., Hauck, S.M., Atkinson, M.J.,
Eriksson, P., Tapio, S.°: Ionising radiation immediately impairs synaptic plasticity-associated cytoskeletal
signalling pathways in HT22 cells and in mouse brain: An in vitro/in vivo comparison study. PLoS ONE
9:e110464 (2014)
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joint first authors
Kucharska, J., del Río, P., Arango-González, B., Gorza, M., Feuchtinger, A., Hauck, S.M.°, Ueffing, M.:
Cyr61 activates retinal cells and prolongs photoreceptor survival in rd1 mouse model of retinitis pigmentosa.
J. Neurochem. 130, 227-240 (2014)
Kühn, A., Nieters, A., Köttgen, A., Goek, O.N., Michels, K., Nöthlings, U., Jacobs, G., Meisinger, C.,
Pessler, F., Akmatov, M.F., Kühnisch, J., Moebus, S., Glocker, E., Naus, S., Keimling, M., Leitzmann, M.,
Linseisen, J., Sarioglu, H., von Toerne, C., Hauck, S.M., Wallaschofski, H., Wichmann, H.-E., Illig, T.°:
Feasibility and quality development of biomaterials in the pretest studies of the German National Cohort.
Ly, A.°, Schöne, C., Becker, M., Rattke, J., Meding, S., Aichler, M., Suckau, D., Walch, A.K., Hauck, S.M.,
Ueffing, M.°: High-resolution MALDI mass spectrometric imaging of lipids in the mammalian retina.
Histochem. Cell Biol. 143, 453-462 (2015) [published online 2014]
Menzler, J., Channappa, L., Zeck, G.°: Rhythmic ganglion cell activity in bleached and blind adult mouse
retinas. PLoS ONE 9:e106047 (2014)
Molin, S.#, Merl, J.#, Dietrich, K.A., Regauer, M., Flaig, M., Letulé, V., Saucke, T., Herzinger, T., Ruzicka, T.,
Hauck, S.M.°: The hand eczema proteome: Imbalance of epidermal barrier proteins. Br. J. Dermatol. 172,
Muda, K., Bertinetti, D., Gesellchen, F., Hermann, J.S., von Zweydorf, F., Geerlof, A., Jacob, A., Ueffing,
M., Gloeckner, C.J., Herberg, F.W.°: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA
phosphorylation of LRRK2 and disrupts its interaction with 14-3-3. Proc. Natl. Acad. Sci. U.S.A. 111,
E34-E43 (2014)
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joint first authors
2147-2161 (2014)
Pischedda, F., Szczurkowska, J., Cirnaru, M.D., Giesert, F.H.H., Vezzoli, E., Ueffing, M., Sala, C.,
Francolini, M., Hauck, S.M., Cancedda, L., Piccoli, G.°: A cell surface biotinylation assay to reveal
membrane-associated neuronal cues: Negr1 regulates dendritic arborization. Mol. Cell. Proteomics 13,
733-748 (2014)
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Sabag, A.D. , Smolkin, T. , Mumblat, Y., Ueffing, M., Kessler, O., Gloeckner, C.J., Neufeld, G.°: The role of
the plexin-A2 receptor in semaphorin-3A and semaphorin-3B signal transduction. J. Cell Sci. 127, 5240-5252
(2014)
Sacco, F.°, Boldt, K., Calderone, A., Panni, S., Paoluzi, S., Castagnoli, L., Ueffing, M., Cesareni, G.°:
Combining affinity proteomics and network context to identify new phosphatase substrates and adapters in
growth pathways. Front. Genet. 5:115 (2014)
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Texier, Y., Toedt, G., Gorza, M., Mans, D.A., van Reeuwijk, J., Horn, N., Willer, J., Katsanis, N., Roepman,
R., Gibson, T.J., Ueffing, M., Boldt, K.°: Elution profile analysis of SDS-induced subcomplexes by
quantitative mass spectrometry. Mol. Cell. Proteomics 13, 1382-1391 (2014)
Uhl, P.B., Szober, C.M., Amann, B., Alge-Priglinger, C., Ueffing, M., Hauck, S.M., Deeg, C.A.°: In situ cell
surface proteomics reveals differentially expressed membrane proteins in retinal pigment epithelial cells
during autoimmune uveitis. J. Proteomics 109, 50-62 (2014)
(2014)
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joint first authors
von Toerne, C., Menzler, J., Ly, A., Senninger, N., Ueffing, M., Hauck, S.M.°: Identification of a novel
neurotrophic factor from primary retinal Müller cells using SILAC. Mol. Cell. Proteomics 13, 2371-2381
(2014)
Waschbüsch, D.°, Michels, H., Strassheim, S., Ossendorf, E., Kessler, D., Gloeckner, C.J., Barnekow, A.:
LRRK2 transport is regulated by its novel interacting partner Rab32. PLoS ONE 9:e111632 (2014)
page 243 of 247
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joint first authors
Research Unit Radiation Cytogenetics
Abend, M.°, Azizova, T.V., Müller, K., Dörr, H., Senf, S., Kreppel, H., Rusinova, G., Glazkova, I.,
Vyazovskaya, N., Schmidl, D., Unger, K., Meineke, V.: Gene expression analysis in Mayak workers with
prolonged occupational radiation exposure. Health Phys. 106, 664-676 (2014)
Abend, M.°, Azizova, T.V., Müller, K., Dörr, H., Senf, S., Kreppel, H., Rusinova, G., Glazkova, I.,
Vyazovskaya, N., Unger, K., Meineke, V.: Independent validation of candidate genes identified after a whole
genome screening on Mayak workers exposed to prolonged occupational radiation. Radiat. Res. 182,
299-309 (2014)
Buck, A., Halbritter, S., Späth, C., Feuchtinger, A., Aichler, M., Zitzelsberger, H., Janssen, K.P., Walch,
A.K.°: Distribution and quantification of irinotecan and its active metabolite SN-38 in colon cancer murine
model systems using MALDI MSI. Anal. Bioanal. Chem. 407, 2107-2116 (2015) [published online 2014]
Maroschik, B., Gürtler, A., Krämer, A., Rößler, U., Gomolka, M., Hornhardt, S., Mörtl, S., Friedl, A.A.°:
Radiation-induced alterations of histone post-translational modification levels in lymphoblastoid cell lines.
Radiat. Oncol. 9:15 (2014)
9:e107069 (2014)
Sriharshan, A., Azimzadeh, O., Caldwell, R.B., Tapio, S.°: Proteomic strategies: SILAC and 2D-DIGE powerful tool to investigate cellular alterations. Methods Mol. Biol. 1101, 369-392 (2014)
Unger, K., Heikenwälder, M.°: Analysis of chromosomal aberrations in murine HCC. Methods Mol. Biol.
1193, 213-226 (2014)
+
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joint first authors
Research Unit Scientific Computing
Ceruto, T.°, Lapeira, O.°, Tonch, A.°, Plant, C.°, Espín, R.A.°, Rosete, A.°: Mining medical data to obtain
fuzzy predicates. Lecture Notes Comp. Sci. 8649, 103-117 (2014)
Endesfelder, D., Burrell, R.A., Kanu, N., McGranahan, N., Howell, M., Parker, P.J., Downward, J., Swanton,
C., Kschischo, M.°: Chromosomal instability selects gene copy number variants encoding core regulators of
proliferation in ER+ breast cancer. Cancer Res. 74, 4853-4863 (2014)
#
#
Endesfelder, D. , zu Castell, W. , Ardissone, A., Davis-Richardson, A.G., Achenbach, P., Hagen, M.,
Feng, J.°, He, X.°, Hubig, N.°, Böhm, C.°, Plant, C.°: Compression-based graph mining exploiting structure
primitives. Proc. IEEE Inst. Electr. Electron. Eng., 181-190 (2013)
Goebl, S.°, Meyer-Baese, A.C.°, Lobbes, M.B.I.°, Plant, C.°: Segmentation and kinetic analysis of breast
lesions in DCE-MR imaging using ICA. Lecture Notes Comp. Sci. 8649, 45-59 (2014)
Grigoriev, I.#, zu Castell, W.#, Tsvetkov, P., Antonov, A.V.°: AERS spider: An online interactive tool to mine
statistical associations in Adverse Event Reporting System. Pharmacoepidemiol. Drug Saf. 23, 795-801
(2014)
Khakhutskyy, V.°, Schwarzfischer, M.°, Hubig, N.°, Plant, C.°, Marr, C.°, Rieger, M.A.°, Schröder, T.°,
Theis, F.J.°: Centroid clustering of cellular lineage trees. Lecture Notes Comp. Sci. 8649, 15-29 (2014)
Mai, S.T.°, He, X.°, Hubig, N.°, Plant, C.°, Böhm, C.°: Active density-based clustering. Proc. IEEE Inst.
Electr. Electron. Eng., 508-517 (2013)
Pasquini, L., Tonch, A., Plant, C., Zherdin, A., Ortner, M., Kurz, A., Förstl, H., Zimmer, C., Grimmer, T.,
Wohlschäger, A., Riedl, V., Sorg, C.°: Intrinsic brain activity of cognitively normal older persons resembles
more that of patients both with and at-risk for Alzheimer's disease than that of healthy younger persons.
Brain Connect. 4, 323-336 (2014)
Roylance, R.#, Endesfelder, D.#, Jamal-Hanjani, M.#, Burrell, R.A.#, Gorman, P.A., Sander, J., Murphy, N.C.,
Birkbak, N.J., Hanby, A.M., Speirs, V., Johnston, S.D., Kschischo, M., Swanton, C.°: Expression of
regulators of mitotic fidelity are associated with intercellular heterogeneity and chromosomal instability in
primary breast cancer. Breast Cancer Res. Treat. 148, 221-229 (2014)
(2014)
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joint first authors
Research Unit Sensory Biology and Organogenesis
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#
Pujol-Martí, J. , Faucherre, A. , Aziz-Bose, R., Asgharsharghi, A., Colombelli, J., Trapani, J.G.,
López-Schier, H.°: Converging axons collectively initiate and maintain synaptic selectivity in a constantly
remodeling sensory organ. Curr. Biol. 24, 2968-2974 (2014)
page 246 of 247

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