Oogenesis Key Concepts Female Reproductive Tract 1 2 3

Oogenesis Key Concepts Female Reproductive Tract 1 2 3

Oogenesis
Animal Development
1
Key Concepts
Female Reproductive Tract
Ovary
Oogenesis
Follicles
Ovulation
Corpus Luteum
Molecular Activity
Primordial Germ Cells (PGCs)
Animal Development
2
Female Reproductive Tract
Ovary
Oviduct
Uterus
Vagina
Animal Development
3
Ovary
Medulla
Cortex
Follicles
Primordial
Germ Cells
Animal Development
4
Oogenesis: Overview
Embryogenesis
Adults
Animal Development
5
Oogenesis: Part 1
Primordial Germ
Cells
Oogonia
Primary Oocytes
Primary Follicle
Animal Development
6
Oogenesis: Part 2
Primary
Oocytes
Secondary
Oocytes
Polar Body
Ovulation
Fertilization
Zygote
7
Animal Development
Follicle Development
Primordial Follicle-> Primary Follicle-> Secondary Follicle-> Graafian
Follicle-> Ovulation-> Corpus Luteum-> Corpus Albicans
8
Animal Development
Primary Follicle
Oocyte
Follicle Cells
Primordial Follicle
Primary Follicle
Animal Development
9
Secondary Follicle
Stratum
granulosum
Theca folliculi
Theca interna
Theca externa
Zona pellucida
Secondary
Follicle
Animal Development
10
Graafian Follicle
Antrum
Graafian
Follicle
Animal Development
11
Ovulation
Ovulation
Oviduct
Animal Development
12
Corpus Luteum
Corpus lutem
Animal Development
13
Corpus Luteum
Corpus lutem
Lutein cells
Ovarian cycles
Granulosa lutein cells
Theca lutein cells
Animal Development
14
Molecular Activity
Lampbrush Chromosomes
Selective gene amplification
Nucleolus
Animal Development
15
Molecular Activity: Nurse Cells
Nurse cells
Oocyte
Follicle cells
Drosophila
Animal Development
16
Molecular Activity: Nurse Cells
Tritiated Cytodine
Time
Location
1 hour
Nucleus (nurse cells)
5 hours
Cytoplasm (nurse cells)
Cytoplasm (oocyte)
Source: Bier
Animal Development
17
Molecular Activity: Bloodstream
Protein Yolk
Fatty Yolk
Follicle cells
Microvilli
Zona pellucida
Oocyte
Pinocytosis
Animal Development
18
Molecular Activity: Yolk
Yolk
Oocyte
RER of Oocyte
Liver
Yolk plateletes
Mitochondria of
oocyte
19
Animal Development
Molecular Activity: Yolk
Protein
kinase
Hypothalamus
stimulates anterior
pituitary
Calcium
Anterior Pituitary
secretes LH & FSH
LH & FSH
stimulates gonads to
produce estrogen
Estrogen
stimulates liver to
produce vitellogenin
Oocyte
converts vitellogenin to
Phosvitin & Lipovitellin
Mitochondria
converts (phosvitin + ATP)
to Yolk Platelets
20
Animal Development
Molecular Activity: Yolk
P32 in NaH2PO4
Time
Liver
Blood
Oocyte
6 hours
164
38
0.22
12 hours
101
45
4.10
Source: Flicksinger & Rounds
Animal Development
21
Molecular Activity
Glycogen
Lipids
Microfilaments
Various cell
organelles
Cortical
granules
Animal Development
22
Molecular Activity: Egg Coats
Primary
Membranes
-
oocyte
-
chorion
vitelline
membrane
zona pellucida
Animal Development
23
Molecular Activity: Egg Coats
Secondary
Membranes
-
nurse cells
follicle cells
accessory
cells
Animal Development
24
Molecular Activity: Egg Coats
Tertiary
Membranes
-
reproductive
tract
-
inner shell
membrane
-
jelly coat
Animal Development
25
Origin of Primordial Germ Cells
Gonads
-
-
mesoderm (germinal ridge)
germinal ridge--> lateral plate mesoderm
male vs female
-
male--> PGCs + sex cords = seminiferous tubules
female--> PGCs + cortex = ovary
Male Bufo
-
Bidders organ
Animal Development
26
Origin of Primordial Germ Cells
Primordial Germ Cells
-
originate outside of the gonads
site of origin varies
-
frogs: endoderm (germ plasm)
-
Drosophila: posterior pole
salamanders: lateral plate mesoderm
birds & reptiles: germinal crescent (hypoblast)
mammals: posterior wall of yolk sac; near
allantois
Animal Development
27
Origin of Primordial Germ Cells
Primordial Germ Cells
-
-
originate outside of the gonads
site of origin varies
move to gonads by:
-
invasion (migration)
metastasis (blood transport)
teratoma
Animal Development
28