Synthe sche Biologie: Ethik und Forschungsförderung in Europa
Transcription
Synthe sche Biologie: Ethik und Forschungsförderung in Europa
!"#$%&'()%&*+,-.-/,&0*1$%,2 3#4*5-6()%3#/(7864&63#/*,# 136-9: !"#$%&!'()*"+,-./0%#' !"#$%&'()*+,-./'01,'21,'34567/'(,89::1';",&&1# <,=&">1.9'?=#$,@A';#=%B ;<=>?*@,&# =A*B3#,*C>=> ?"&',&.'&9@.*1C&)*1'<,=:=A,1D E F,1:1'51G@,C=@1@/'"81#'H1@.#":',&.'-,1 E I@J1@-%@A',@A1@,1%#&KJ,&&1@&)*"L:,)*1# 2#,@H,B,1@',@'-1#'<,=:=A,1M E N1#&.1::%@A'O=@'@1%1@'%@-'%@@".P#:,)*1@ 8,=:=A,&)*1@'(9&.1+1@M (9@.*1C&)*1'<,=:=A,1 Q=#&)*%@A&"$CO,.R.'(< 4;S! !==#1T&)*1';1&1.H'-1#'5UI'(9@.*1&1 Carlson 2009. Nat Biotech. [email protected]#V'A:=8":1&'!1-,1@,@.1#1&&1 W!"#$%&%'(&%"&%)*%+#"#$,#"#$% -&%+./%01,2"3(44.++.(0"'(& #$%"5#*/6"('"7.(%#$.8,2".++*%+ *0/%&#,9%:",+"#$%.&";&+# (&/%&"('"<*+.0%++:","+#*/6"(' #$.+"+8.%01;8"4.2%+#(0%MMMX <"#")$'Y8"+"'=@'(< !"9'Z[.*/'Z[\[ ]('^=@A#1&&'I@*_#%@A'H% U%.H1@`a,&,$1@'-1#'(< S%#=B1"@';#=%B'=@'S.*,)&',@ (),1@)1'"@-'U1J'b1)*@=:=A,1& I&,:=+"#'^=@>1#1@H'\cde ]('2#=f1$.1'H%'(<KS0(I'b*1+1@ Synthetic Aesthetics Science/Society understanding JCVI Ethics non-physical harm: Hastings Synbioproject: WWCIS Web portal dual use/biosecurity OECD-NAS-RS Symposium SynbERC: Thrust IV - Human Practices JCVI-MIT-CSIS Risks and benefits of synthetic genomics Several biosecurity related activities, e.g. NSABB, guidelines SB 1.0 2004 SB 2.0 2005 2006 SB 3.0 2007 SB 4.0 2008 2009 2010 and beyond S%#=BR,&)*1'2#=f1$.1'H%'(<KS0(I'b*1+1@ ESF: SYNMOD (WP5) CISYNBIO: cinema and SB Synth-Ethics: general ELSI FUGE: ethics, STS, complexity SYBHEL: ethics - human health Biosafety Austria/EU - China BBSRC Networks incl. ELSA TARPOL: WP1 + WP5 COSY Communicating SB TESSY Towards a SB Roadmap SYNBIOSAFE Safety and ethical aspects of SB PACE: incl. ethical considerations concerning artificial cells SB 1.0 2004 SB 2.0 2005 2006 SB 3.0 2007 SB 4.0 2008 2009 2010 and beyond g'b*1+1@>1:-1# 1) System assembly and molecular and cellular complexity in a context of Darwinian evolution 2) Computational design tools 3) The biosystems design laboratory 4) The social context S(Q'S]aY(hU<4Y Zg'2#=B=&":&'(.%>1'\ \i'1,@A1:"-1@',@'(.%>1'Z c'B=&,CO'81J1#.1. e'2#=f1$.1'J1#-1@'A1>_#-1#. Kj')"'k['4@-,O,-%":'2#=f1).&/'-"O=@'@%#'\'S0(I 1$%,2*3#4*5-6()%3#/(7864&63#/ ,#*136-9: E I%&J"*:'#1:1O"@.1#`,@.1#1&&"@.1#'0R@-1# E ]^/'5S/'Qa/'U0/'6N/'Ib E [email protected]#O,1J&'+,.'@"C=@":1@ Q=#&)*%@A&>_#-1#1#@'3f1J1,:&'Z'B#='0"@-7 Q=#&)*%@A&"$CO,.R.1@',@'S%#=B" AT-1 AT-2 CH-1 DE-1 DE-1 FR-1 FR-2 NL-1 NL-2 UK-1 UK-2 (<V'S,@1'51G@,C=@&>#"A1 biocircuits using standard biological parts + + + + + + + + ? + + biocircuits without standard biological parts? + + + + + + + + ? + + engineering cells to produce fine chemicals + - + + + + + + + + + creating artificial life - + + - - + + - ? + + computer software for biocircuit design - + + + + + + + - + - artificial ecosystems - - + ? ? + + - - + - enlarged genetic alphabet + + + + + + + + + + + DNA with chemically different backbone + + + + + + + + + + + minimal genome - - + + + + + + ? + + understanding the origin of life + - - + + + + - + + + S#A18@,&&1'Q_#-1#&,.%"C=@ SB community ELSA community Austria – + – + + France + +/– – – – Germany + + + + – Netherlands + + + +/– + Switzerland + +/– + +/– + UK + + + + + Land SB Förderu n g ELSA Förderu n g Link Förderung / community lV'NQ0(']#&B#%@A/'(":H8%#A 2#=.1,@1'ZM[ I+9:"&1`^".":"&1'+,.'@,)*.K$"@=@,&)*1@'I+,@=&R%#1@ Ethionine Catalase Bacillus subtilis 1A55 Methionine Norleucine m%A1@-',@@=O"COV <%@-1&+,@,&.1#'!,n1#:1*@1#'H1,)*@1.1'-,1 81&.1@'()*P:1#Kb1"+&'"%& 6,@1+"'"@-'(9@.*1C)'<,=:=A9 Orthosome Text www.cisynbio.com Bio:fiction bringt alle zusammen: Filmemacher Kunst- & Kulturschaffende Civil Journalists Presse und Medien Wirtschaft, Biotechunternehmen Wissenschafter O,-1= Danke !