Dalhousie University R e
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Dalhousie University R e
Dalhousie University Faculty of Medicine Department of Surgery Research and Education Report 2010 Table of Contents Agility and Accountability Dr. David Kirkpatrick, Head, Department of Surgery 1 Research and Education Drive Quality Care Dr. Greg Hirsch, Director of Research, Department of Surgery 2 Training a Surgeon, a Complex Task Dr. Brock Vair, Director of Education, Department of Surgery 3 Every Donated Organ Counts Dr. Ian Alwayn, Transplant Surgeon 4 Restoring Confidence and Energy Dr. James Ellsmere, Gastrointestinal Surgeon 6 Kids – Returning to their Sports and Activities Dr. Ron El-Hawary, Pediatric Orthopaedic Surgeon 8 A More Precise Diagnosis and Treatment Dr. Drew Bethune, Thoracic Surgeon 10 You Never Stop Learning Dr. Jason Williams, Educator, Plastic Surgeon 12 Finding Answers That Will Improve Patient Care Resident Researcher, Dr. Devon Richardson 13 Research and Teaching, Integral to a Surgical Career Resident Teacher, Dr. Dafydd Davies 13 Measurable Indicators in Research and Education 14 Catalogue of Accomplishments: Appendix 17 Cover Photo: Dr. Jason Williams (centre), teaching unit with residents Dr. Reza Ahmadzadeh (far left) and Dr. Amanda Murphy (far right). Medical student Adam Harris is left of Dr. Williams. Department of Surgery Annual Research & Education Report 2010, is an annual publication of the Department of Surgery. Production: Elaine Marsh Editors: Dr. Greg Hirsch, Dr. Adrian Park and Dr. David Kirkpatrick Contributors: Melanie Jollymore Photography: Jamie Crosby Printing: The Printer Ltd. Dalhousie University | 1 Agility and Accountability in Changing Times Dr. David Kirkpatrick, Head, Department of Surgery I n surgery, as in any health care discipline, we are constantly evolving how we do things. This is not change for the sake of change, but for the sake of improving the quality of care we provide. Only through research can we know what to change and how to change it, and only through education can we transfer new methods and ways of thinking to our trainees and colleagues in the field. Research and education are the dual pillars that support our mission to lead the way to highly effective patient care and the best possible health outcomes. The challenge today is to fulfill our mission in the face of rising demand for our clinical services and declining human and financial resources to deliver them. To do so requires the agility to adapt to a changing environment, the foresight to anticipate emerging needs, and the creativity to devise workable solutions. I’m optimistic about the future, because I see that we are developing the culture of flexibility we need to re-structure our health care teams and streamline our processes for maximum effectiveness and efficiency. For example, we are now collaborating with hospitals across Atlantic Canada to save money on surgical supplies by purchasing as a group. We’re also sharing specialists across institutions so their skills can be fully utilized and smaller communities can benefit from their services. In the past year, we have developed systems for measuring our productivity in research and education. We can now generate detailed reports to demonstrate our accountability to government for the research and education funds we receive through our alternative funding plan (AFP). The AFP is fundamental to our mission, as it allows us to conduct the research and teaching that are essential to advancing patient care. You will see many fine examples of the progress we are making as you read through this report. These are exciting times. We are working in the midst of an explosion of knowledge and technology that makes our job more complex than ever, but also provides us with the tools, insights and inspiration to make major improvements in patient care. And this is what we’re determined to do. For ultimately our highest accountability is to the people we serve. 2 | Department of Surgery Research and Education Drive Quality Care Dr. Greg Hirsch, Director of Research T his year our Department of Surgery report broadens beyond last year’s focus on research to highlight the importance of education in the department. Research and education feed directly into one another and both are essential to our task of advancing patient care through knowledge. Of course, the success of all this research training relies on the vibrancy of our facultyled research programs. We are fortunate to have extremely talented and dedicated researchers among our faculty. Many are global and national leaders in sophisticated specialties like heart, liver and multi-organ transplant, minimally invasive techniques, spinal surgery, deep-brain stimulation, and reconstructive surgery. One of our key missions is to train the next generation of research-minded surgeons. All medical students, residents and fellows learn research skills as they go through our clinical training programs. They often take part in clinical research studies that show them firsthand how research is woven into the fabric of high-quality clinical care. Last year, our researchers shared their findings in more than 160 peerreviewed publications. They continued to demonstrate stellar performance in funding competitions, capturing more than $15 million in new research grants. I am proud to report that the department now holds grants totaling more than $55 million. Exposure to research helps clinical trainees develop the skills and attitudes they need to incorporate research into their future surgery careers. It is the attitude, as much as anything, we seek to foster. We want our trainees to learn how to question why things are done a particular way, demand solid evidence, and go about finding answers themselves if that’s what needs to be done to ensure our practices are really evidence-based. The researchers you will meet in this report take a step beyond the expected. For example, Dr. James Ellsmere is working with a team of biomedical engineers to develop new devices for minimally-invasive gastrointestinal surgeries. Meanwhile, Dr. Ron El-Hawary is pioneering a sophisticated means of assessing the stability of spinal fusion surgery and working with a clinical psychologist to understand the impact of post-operative pain. Our Clinician Investigator Program (CIP) is designed for those surgery residents who plan to make laboratory-based scientific research a major part of their work. The CIP provides them with funding and supervision to complete a masters or doctoral degree over the course of an extended residency. Our CIP residents learn how to conduct successful laboratory research programs that directly address the challenges they face in their work as surgeons. The kind of expertise and leadership you will read about in this report attracts top trainees and professional staff who want to learn, teach and practice highly advanced procedures in a research-rich environment where they can help generate new knowledge for even better care in the future. Dalhousie University | 3 The Multi-faceted Pursuit of Training New Surgeons Dr. Brock Vair, Director of Education T he role of surgeons today extends far beyond the operating theatre. In addition to our work as skilled and knowledgeable clinicians, today’s surgeons must be accomplished communicators, productive researchers, and effective leaders, teachers and advocates for healthier lifestyles and policies. The question for us, as a department, is how do we educate the next generation of surgeons to perform in all these roles? And, how do we evaluate their performance as they progress through the stages of their training? It’s a complex task, further complicated by new national regulations that significantly reduce the number of hours residents are allowed to work on clinical duty each week. We are working closely with the Postgraduate Dean’s office to address the challenges posed by reduced resident work hours, in terms of training, evaluation, staffing and professionalism. Teaching procedures on simulators in the Skills Centre for Health Sciences is one important way we provide technical training outside clinical work hours. Simulator training has the added benefit of ensuring trainees are proficient—in skills as basic as suturing and as complex as removing tumours—before working with real patients. In communication, teaching and collaborative skills, we need to teach by example and by providing clear guidelines, lots of opportunities for practice, and ongoing constructive feedback. To this last end, we’ve introduced a new ‘360-degree’ evaluation process, which continuously gathers feedback from everyone on the health care team who interacts with our trainees. As we refine our programs for the future, we can look with pride at our accomplishments of the past. For example, Dalhousie’s undergraduate medical ‘Class of 2009’ placed first in Canada in the surgery section of the LMCC (Licentiate of the Medical Council of Canada) exams. Our residents consistently achieve high marks in the Royal College exams. And, we continue to attract talented surgeons and scientists from around the world to pursue fellowship training in areas of excellence such as minimally invasive surgery, otolaryngology, transplant surgery, orthopaedics, and thoracic surgery. Our dynamic training environment is further enhanced by our department’s keen interest in research, as you will see in the research stories on the pages that follow. 4 | Department of Surgery Transplant Surgery: Making the Most of Each Precious Donation Dr. Ian Alwayn, Dalhousie Abdominal Transplant Surgeon Researchers look for new ways to optimize transplant outcomes T ransplant surgery has come a long way in the past decade, but there are still many challenges for surgeons and their patients. Chief among these is the shortage of healthy organs for transplant. Every year in Canada, hundreds of people die while waiting for an organ. And, many donated organs are not in perfect condition, especially by the time they reach their intended recipient. The graduate students are developing a novel way to deliver protective agents into the cells of the organ to minimize this damage (see sidebar). Keeping the donated organ as healthy as possible is one side of the equation. Keeping the recipient healthy is the other. “We need to make every donated organ count,” says Dr. Ian Alwayn, a Dalhousie transplant surgeon who heads the kidney and multi-organ transplant programs at the QEII Health Sciences Centre. “We need to do everything we can to ensure the best possible outcomes for transplant patients, so we do not waste this precious gift of life.” “Organ recipients must take anti-rejection drugs, but these promote weight gain, which can lead to obesity and diabetes,” notes Dr. Alwayn. He and his colleagues in the transplant programs encourage patients to be physically active, but they want to take the exercise one step further. They are collaborating with Dalhousie exercise psychologist Dr. Melanie Keats on a pilot study to introduce active video gaming to their transplant patients. Dr. Alwayn is working with graduate students to devise new ways of preserving the healthy function of transplanted organs from deceased donors. “Removing an organ from its blood supply triggers a process of oxidative damage and inflammation,” explains Dr. Alwayn. “Putting the organ on ice slows this process down, but the organ sustains further injury when it is re-perfused with the recipient’s blood.” “People are more likely to exercise if they perceive the activity to be fun,” says Dr. Alwayn, who has involved a physiotherapist and nurse practitioner in the project. “The system we’re using allows people to create online communities, which is motivating, and it also allows us to monitor how often and how intensely they are exercising. The better their overall health, the better they will do with their transplanted organ.” Preserving quality of donor organs • Transplant surgeon Dr. Ian Alwayn is leading a research effort to develop means of protecting donated organs from oxidative damage that occurs between the time the organ is removed from the donor and transplanted into the recipient. He is supervising surgery resident Dr. Scott Livingstone—a masters student through the Department of Surgery’s Clinician Investigator Program—and graduate student Kimberley Savage in these labbased investigations. The researchers have engineered a cell-penetrating peptide to carry protective agents into Dalhousie University | 5 Sisters Share Profound Gift of Life M anon Landry did not hesitate for a second when faced with the decision to donate one of her kidneys to her sister, Dominique. “I had to do it,” says Manon. “There was no question.” Dr. Ian Alwayn performed the successful transplant in August 2009, using a laparoscopic technique with the donor to minimize the impact of the surgery on this healthy individual. This was not Dominique’s first kidney transplant—her kidneys failed dramatically when she was only 19. “The doctors told me I would have died within a day, if I hadn’t received medical attention when I did,” she recalls, adding that Manon rushed her to the hospital after finding her literally dying in their Moncton apartment on a Friday afternoon. “It was so sudden. I had no symptoms, apart from lack of energy, before that day.” Dominique received a kidney from an anonymous donor in 1986. By 2000, it was wearing out due to the long-term effects of her immune system’s attempts to reject it. Her situation became critical again in 2008, forcing her onto dialysis. Hemodialysis in the hospital was so hard on her, Dominique switched to peritoneal dialysis. This involved filling her own abdominal cavity with fluid, through an implanted catheter, four times a day for a year. Meanwhile, Manon underwent a battery of tests in Moncton to confirm her kidney would be a match and that she was healthy enough to thrive with one kidney. The results were sent to Halifax, where Dr. Alwayn and his team determined that Manon’s kidney was a perfect match. As a result, it is working very well for Dominique and she doesn’t need to take as much anti-rejection medication as she did with her first donor kidney. “I have more energy and feel stronger than I have in years,” says Dominique. “Manon has given me such an incredible gift.” the organs’ cells. They are currently working with a protein that may protect the organ from oxidative damage... but the same technology could be used to deliver proteins for preventing rejection or infection of the donor organ. • Dr. Alwayn is also working with Canadian Blood Services and colleagues nationwide to develop the Living Donor Paired Exchange Registry. The registry helps people who need a kidney transplant—but do not have a relative who’s compatible or able to donate—connect with a match more quickly. Photo captions: Page 4: Dr. Ian Alwayn Page 5, Top: Dominique and Manon celebrate following their recoveries. 6 | Department of Surgery Bariatric Surgery: An Effective Approach to Obesity Dr. James Ellsmere, Dalhousie Gastrointestinal Surgeon S tomach-reduction surgery helps people lose the weight and the medications. Over the past two years, Dalhousie surgeons Drs. James Ellsmere and Dennis Klassen have performed stomach-reduction surgery on more than 170 morbidly obese people. The results have been dramatic. On average, these patients have lost an astounding 65% of their excess body weight. Many have been able to stop taking medication for diabetes, high blood pressure, high cholesterol and other conditions that go hand-in-hand with obesity. “The procedure we use is incredibly effective,” says Dr. Ellsmere, explaining that the ‘vertical sleeve gastrectomy’ permanently removes 85% of the stomach. He performs the surgery laparoscopically, so it is minimally invasive. “When combined with a healthy diet and physical exercise, it transforms people’s lives.” To qualify for the surgery, candidates must prove they are motivated to change their eating and lifestyle habits. As Dr. Ellsmere explains, people who are referred to him first meet with nurse practitioner Diana Lawlor, dietitian Deanne Ortman and clinical psychologist Dr. Michael Vallis. “We are all working together through Capital Health’s Obesity Network,” notes Dr. Ellsmere. “This multi-disciplinary team involves health care professionals, researchers, educators and government in a concerted effort to address the obesity epidemic.” If people commit to the necessary changes, they can enroll in the weight-loss surgery program. A dietitian works with them to help them lose weight before the surgery— it is high risk to operate on anyone over 400 lbs—and supports them to eat properly after surgery, as well. “We’re assessing short- and long-term outcomes in terms of weight loss, diabetes and health economics,” Dr. Ellsmere says. “So far we’re seeing a tremendous impact.” Within 18 months of surgery, patients have lost more than half of their excess weight and regained their blood-sugar control. Some are saving $3,000 a year, or more, because they no longer need medication. According to Dr. Ellsmere, the surgery produces far better results than weight-loss drugs. “Studies show that a combination of drugs, diet and exercise helps people lose about 5% of their excess weight… compared to 65% through our approach.” For morbidly obese people, weight loss of this magnitude gives them confidence and energy to re-engage in society. The benefits, however, go far beyond the individual. As Dr. Ellsmere notes, “We’re substantially reducing the overall burden of disease on our health care system and society as a whole.” Advancing minimally invasive gastrointestinal surgery • A general surgeon, Dr. James Ellsmere specializes in endoscopic and laparoscopic approaches to gastrointestinal surgeries, including weight-loss, anti-reflux, biliary and pancreatic procedures. • Dr. Ellsmere is working with collaborators and trainees in Dalhousie’s School of Biomedical Engineering to create new tools and implants for making various endoscopic and laparoscopic procedures safer and more effective. As director of the Skills Centre for Health Sciences, he has been involved in testing experimental devices in pre-clinical models. Dalhousie University | 7 Lifesaving Surgery for Dwayne MacDonald I t’s no exaggeration when Dwayne MacDonald says weight-loss surgery saved his life. At 545 lbs, he was plagued by recurring bouts of severe cellulitis, a potentially fatal skin infection to which obese people are vulnerable. At the same time, he suffered from sleep apnea and intense hip pain. Unable to work, he was living with his parents on their farm near Port Hawkesbury, NS. “I felt hopeless, beyond repair,” recalls Dwayne, only 41 at the time. “I began writing farewell letters to my family and friends.” In early 2009, concerned for Dwayne’s life, his family doctor referred him to Dr. James Ellsmere for weight-loss surgery. “The call to come to an information session was like a life preserver,” says Dwayne. The recent death of his sister had Dwayne re-evaluating his own life. He knew it would be difficult to lose 120 lbs to qualify for stomach-reduction surgery, but he was determined. “I told myself ‘I can do anything for a day’,” he says. “I committed myself to following the diet they gave me, one day at a time.” By the time his surgery rolled around in October 2009, he had lost 175 lbs. Less than a-year-and-half later, he is approaching his goal of 220 lbs, a healthy weight for his large frame. “I’m on a voyage of self discovery,” says Dwayne, who is actively working on his parents’ farm and has started his own business, ‘I Know A Guy,’ doing all manner of odd jobs. Unlike his previous isolation, he’s involved in community organizations and events, coaching other people through weight-loss surgery, making friends and getting out. “I’m so grateful to the staff in the weight-loss surgery program, they’re there for me 100%.” • With colleagues at Harvard Medical School, Dr. Ellsmere is running a clinical trial to assess a novel surgical navigation system to improve laparoscopic ultrasound in assessing pancreatic cancer. • Dr. Ellsmere directs the Division of General Surgery’s fellowship program in minimally invasive surgery, and teaches/supervises medical students, residents and fellows. He teaches advanced endoscopic techniques to surgeons and trainees across North America through courses offered by the Society of American Gastrointestinal and Endoscopic Surgeons, the American Society of Gastrointestinal Endoscopy and the Canadian Association of General Surgeons. Photo captions: Page 6: Dr. James Ellsmere Page 7, Top: Dwayne MacDonald’s campaign photo; he recently ran for county council. Page 7, Bottom: Dwayne enjoys working outdoors on the family farm. 8 | Department of Surgery Orthopaedics: Solutions for Scoliosis Dr. Ron El-Hawary, Dalhousie Pediatric Orthopaedic Surgeon Dr. Ron El-Hawary pioneers a new way to monitor spinal fusion stability M any young people with severe scoliosis need spinal fusion surgery to prevent their spines from continuing to curve and twist. “If we don’t surgically stop the scoliosis from progressing, the misaligned spine will eventually put pressure on the heart, lungs and other organs,” says Dalhousie orthopaedic surgeon Dr. Ron El-Hawary. “This can be dangerous.” Dr. El-Hawary performs about 70 spinal surgeries on children and adolescents each year at the IWK Health Centre in Halifax, implanting rods into the vertebrae to reduce the curvature and holding the spine’s position in place with screws and a bone-grafting compound. He and his research team are exploring how a technique called RSA (radio stereometric analysis) can best be used to monitor the stability of the spine and its implants following fusion surgery. “If any of the parts are moving even a little bit, the spine will continue to deform and we will need to do another surgery,” Dr. ElHawary says. “One the other hand, once we know the spine is solidly fused, the kids can return to their sports and activities.” Dalhousie orthopaedic surgeon Dr. Michael Dunbar is a global leader in developing RSA for predicting implant failure in kneereplacement patients. Dr. El-Hawary and his team are collaborating with Dr. Dunbar to adapt the technology to the more complex structure of the spine. RSA involves putting tiny metal beads into the bone—and often into prosthetic implants as well—during surgery. The threedimensional motion of the beads can then be traced with x-rays to measure the joint’s stability after surgery. Last year Dalhousie biomedical engineering graduate student Antony Francis worked with Dr. El-Hawary to identify key locations in the vertebrae where the metal beads can safely be placed. Now another biomedical engineering student, Alan Spurway, is working with patient x-rays to develop software that takes the variations of individual spines into account. “This software will let us determine the optimal placement of each bead in the unique spine of each patient,” Dr. El-Hawary explains. “We need to place them so our x-ray view will not be blocked by the other metal implants, so we can detect and accurately measure any movement.” He expects to begin enrolling patients in a clinical pilot study of RSA in the fall of 2011. Diverse research interests, strong educational role • One of Canada’s top spinal surgeons, Dr. Ron El-Hawary is involved in multi-site research studies through the international Chest Wall and Spine Deformity Study Group, which examines the effects of scoliosis on the growing spine and chest wall. He also heads the Canadian Pediatric Spine Deformity Study Group, which is part of the Canadian Spine Society. This relatively new group is collecting data and analyzing the results of treatments used for children with scoliosis. • Dr. El-Hawary and his partner, Dr. Jason Howard, are co-investigators on a Canadian Institutes of Health Researchfunded study of pain in children following spinal fusion surgery. Clinical psychologist Dr. Jill Chorney (IWK Health Centre) Dalhousie University | 9 Spinal Fusion Keeps Leslie Barnhart Healthy and Active L eslie Barnhart of Halifax did not know she had scoliosis until one day her soccer coach spotted the misalignment in her spine. When Dr. Ron El-Hawary examined her, he found that her spine was severely curved from side to side, creating a ‘S’ shape down her back. “The curve of my spine was putting pressure on my lungs,” says Leslie, who was 15 at the time. “Dr. El-Hawary said it would start putting pressure on my heart as well, and that the pressure on my organs would get worse, unless I had surgery.” Dr. El-Hawary implanted several titanium rods in Leslie’s spine, twisted them to reduce the curve, and secured her spine’s new position with screws and a bonegrafting compound. “I was an inch and a half taller after the surgery!” she says. “My spine was still curved but it wasn’t putting pressure on anything anymore.” Leslie recovered well from the surgery and was back to playing soccer one year later. She went on to play intramural soccer at Memorial University of Newfoundland, where she has been studying to become a teacher. She plans to return to Nova Scotia later this year to complete her education degree at Mount Saint Vincent University. is heading the five-year study. The researchers want to learn more about the pain scoliosis causes for some children, how anxiety about their upcoming surgery affects their postoperative pain experience, and how to moderate the children’s anxiety and post-operative pain. They are also interested in parents’ influence on their children’s ability to cope with pain, and the economic consequences of the children’s pain. • Dr. El-Hawary plays an active role in education, supervising the research projects of more than a dozen Dalhousie trainees. These include medical students and surgery residents and fellows, as well as graduate students and postdoctoral fellows in biomedical engineering. Photo captions: Page 8: Dr. Ron El-Hawary Page 9, Top: Leslie Barnhart Page 9, Bottom: Leslie walking with dogs Delilah (in arms) and Ernie & Charlie. 10 | Department of Surgery Thoracic Surgery: New Approaches for Better Outcomes Dr. Drew Bethune, Dalhousie Thoracic Surgeon Lung tumour tissue bank holds key to early, precise diagnosis and treatment A collaborative research venture in Halifax could open the door to new ways of diagnosing early lung cancers and customizing treatment for the greatest effect. The cornerstones of the new effort are a lung tumour tissue bank and patient database established by Dalhousie thoracic surgeon Dr. Drew Bethune and pathologist Dr. Zhaolin Xu at Capital Health. “We have banked more than 300 tumour samples from patients so far and will be able to collect new samples and data for many years to come,” says Dr. Bethune, head of Dalhousie’s Division of Thoracic Surgery and the Cancer Care Program at the QEII Health Sciences Centre. Drs. Bethune and Xu have joined forces with Dalhousie molecular biologist Dr. Neale Ridgway and National Research Council scientists to take analysis of the tumour samples to a new, highly sophisticated level. “These scientists have the equipment and know-how to analyze 45,000 genes at a time, or extract individual cancer cells from blood samples containing millions of cells,” says Dr. Bethune. He notes that the researchers are investigating such possibilities as bloodborne biomarkers and even a technique of rinsing the lungs to detect cancer cells early. They are also examining tiny strands of genetic matter called ‘micro RNA,’ which they believe will help them better classify lung cancers. “Traditional pathology studies cannot tell us all we need to know,” explains Dr. Bethune. “Cancers that look the same under the microscope may actually behave quite differently. Defining the molecular characteristics of real people’s cancer cells—and comparing these to what we know about the patients’ treatments and outcomes—will reveal certain patterns. These will help us predict how aggressive a person’s cancer will be, and how likely to metastasize, so we can provide the right treatments at the right time.” Earlier detection and more precise diagnosis and treatment are essential to overcoming lung cancer, the leading cause of cancer deaths in Canada. Cure rates for lung cancer hover at 15%, because it is rarely detected in the early stages and can be difficult to predict and eradicate. In addition to Dr. Bethune’s work with laboratory scientists, Dalhousie thoracic surgeon Dr. Michael Johnston is involved in a national clinical trial of a multi-faceted approach to detecting early lung cancers in high-risk populations. Found early, lung cancer can be cured 80 to 90% of the time. New techniques and treatments for thoracic cancers • Although he is a surgeon, Dr. Drew Bethune explores and uses a wide variety of techniques and treatments for patients with cancers of the lung and esophagus. He works with medical oncologists, radiation oncologists and many others to provide the best possible care. • Dr. Bethune is involved in a large clinical trial of a targeted molecular therapy designed to prevent post-surgical recurrence of a type of lung cancer that tends to strike female non-smokers. Dalhousie University | 11 Laser Treatment Saves John Fenerty’s Life J ohn Fenerty’s brush with death began with a persistent cough. An initial CT scan and subsequent bronchoscopy and biopsy tested negative for lung cancer, so the cough remained a mystery. As an active 49-year-old who had never smoked, John was not a typical candidate for the disease. A month or so later, during a conference in Las Vegas, John began coughing up large quantities of blood. An enhanced CT now revealed a bleeding lesion in the airways, and multiple blood clots in the arteries, of his lungs. Doctors were just able to stabilize the bleeding from the lesion until he could get airlifted home. “Not long after I made it to hospital in Halifax, the bleeding started again… but a lot more than before…and next thing I knew I was in the OR,” says John. “Thankfully, Dr. Bethune was able to stop the bleeding with the laser and get a tissue sample.” This time, the biopsy revealed a rare and aggressive form of lung cancer. John’s fate was balanced on a knife’s edge. The cancer was growing fast, invading more blood vessels and causing further bleeding made worse by the fact that John still needed blood thinners to treat the clots in his lungs. With a second round of laser treatments and coiling of the bleeding blood vessels, the bleeding stopped. The oncology team decided to shrink the tumour and stop further bleeding with radiation and chemotherapy while John remained on blood thinners until it was safe for Dr. Bethune to operate. After finishing the treatments, Dr. Bethune successfully removed John’s left lung to eradicate the cancer. Now, with all the treatments and surgery behind him, John is cancer free and recovering well. “Lung cancer can strike anyone, and quickly,” says John. “The laser equipment saved my life twice. It was the only lifesaving option that was available when it was not safe to do the big lung operation due to the clots. If it wasn’t for the laser, and the skill and dedication of the team at the QEII, I wouldn’t be alive today.” • Dr. Bethune and general surgeon Dr. James Ellsmere are investigating high-frequency ablation of abnormal tissues in the esophagus, to see if this can prevent the lethal form of esophageal cancer that often arises in such tissue. • Dr. Giovanni Luca Carboni, a thoracic surgeon from Switzerland, spent 2010 in Halifax learning advanced techniques of laser surgery, thoracic oncology, and minimally invasive surgery with Dr. Bethune and other members of the Department of Surgery. Photo captions: Page 10: Dr. Drew Bethune Page 11: John Fenerty (2nd from the right) enjoys vacation time with his family. 12 | Department of Surgery Focus on Education Dr. Jason Williams, Educator, Plastic Surgeon Dr. Jason Williams makes surgery education a top priority T he smile of triumph on a student or resident’s face as they master a new skill is one of Dr. Jason Williams’ greatest rewards. An assistant professor in the Division of Plastic Surgery, Dr. Williams devotes a great deal of his time and energy to educating the next generation of surgeons in his field. “I am very committed to our education programs,” says Dr. Williams. “I derive tremendous satisfaction and pride from seeing our trainees succeed.” As a surgeon and surgeon educator, Dr. Williams trains undergraduate medical students and residents in the techniques and procedures of plastic surgery, including postcancer-surgery reconstruction and the repair of burns and hand injuries. On top of his busy clinical and teaching schedule, Dr. Williams is pursuing a Masters degree in medical education through the University of Cincinnati. “I want to gain a deeper understanding of what goes into an effective education program,” he says. “How we structure the program, set objectives, deliver the training, and evaluate our trainees has a profound impact on how well they perform their future roles.” Dr. Williams officially takes the reins as director of the Division of Plastic Surgery’s undergraduate and resident education programs later this year when he completes his Masters. This is a natural progression of his longstanding passion for education, which began while he was in training himself. “I had many inspiring role models during my time as a medical student and resident at Dalhousie,” Dr. Williams notes. “I saw and respected the enormous impact they had on myself and my peers and knew I wanted to play the same role.” He didn’t hesitate to act on his inspiration. As a resident, he won teaching awards for his work with medical students. Soon after joining the faculty, in 2007, he won an excellence award from the Department of Surgery for his undergraduate teaching. As a Masters student, Dr. Williams is designing and evaluating a different kind of education program. He is working with Dalhousie’s Division of Continuing Medical Education to create an online training module so family and emergency physicians can learn how to best manage patients who present with burns and hand injuries. “As a physician or surgeon, you never stop learning,” he says. “Education—of ourselves and others—is an essential part of what we do every day.” Committing to education • Once Dr. Williams completes his Masters degree in Medical Education, he will step into the role of Residency Progam Director for the Division of Plastic Surgery. • Dr. Williams won the Department of Surgery’s award for Faculty Excellence in Undergraduate Training in 2007, his first year of practice. He won the Faculty of Medicine Resident Teaching Award in 2005, and was the first recipient of the Dr. Winston Parkhill Award––given annually in recognition of excellence in medical student teaching by plastic surgery residents. Photo captions: Page 12: Dr. Jason Williams Page 13, Top: Dr. Dafydd Davies Page 13, Bottom: Dr. Devon Richardson Dalhousie University | 13 Spotlight on: Resident Educator Teaching and learning go hand-in-hand for Dr. Dafydd Davies F or surgery resident Dr. Dafydd Davies, teaching is as much a part of his day-to-day life as learning. “As residents learn more and gain skills and confidence, sharing that knowledge with other residents and medical students becomes an important part of our role,” says Dr. Davies. As chief resident in the Division of General Surgery, he has a particular part to play in his fellow residents’ education. “There is a well-defined body of knowledge that we need to gain throughout our residency, but it’s a challenge to track because we’re learning through an apprenticeship model,” notes Dr. Davies. “I work with the other residents to make sure they’re being exposed to all the necessary experiences.” He also coordinates the resident call and operating room schedules, organizes journal discussions, and creates opportunities for other trainees to practice new techniques in the Skills Centre for Health Sciences. Learning by example is the key not only for technical skills, but also for the communication skills that are so important for surgeons. “It takes a lot of sensitivity and diplomacy to develop a trusting relationship with a patient over a few short clinic visits,” Dr. Davies says. “Senior residents and faculty have to consistently demonstrate these skills. We then observe residents’ interactions with patients and provide them with feedback and the opportunity to analyze the situation.” Dr. Davies also teaches research skills to some of his peers. Partway through his residency at Dalhousie, he took a leave of absence to complete a research fellowship in pediatric trauma at the SickKids Hospital/University of Toronto, and obtain a Masters degree in epidemiology from the University of Cambridge, UK. When he finishes his residency this June, he will head back to the University of Toronto for fellowship training in pediatric general surgery. “I would like to return to Halifax to work as an academic surgeon at Dalhousie and the IWK,” he says. “Research and teaching will definitely continue to be integral to my career as a surgeon.” Spotlight on: Resident Researcher Dr. Devon Richardson seeks path to better care for rectal cancer A third-year resident in general surgery, Dr. Devon Richardson has already jumpstarted her research career with a comprehensive study of rectal cancer in Nova Scotia. As she mines the data and produces manuscripts, her findings will have a growing impact on the management of rectal cancer in the province. “I wanted to reveal a clear picture of the incidence, management and outcomes of rectal cancer all across Nova Scotia,” says Dr. Richardson, who examined the health records of everyone in the province who presented with rectal cancer between 2002 and 2006. “I also want to shed light on any disparities in the quality of care.” After gleaning a wealth of information from more than 700 health records, Dr. Richardson is working on a series of papers. These will describe the demographics of rectal cancer in Nova Scotia, what stage it has usually reached by the time of diagnosis, how it is detected, diagnosed, and treated, and how patients fare in terms of recurrence, survival and quality of life in health districts across Nova Scotia. “As a surgery resident, I’m particularly interested in issues related to surgical treatment,” notes Dr. Richardson. “I’m exploring how surgeons’ knowledge influences their surgical practices and how this in turn impacts such important outcomes as sphincter preservation, lymph node harvest and local cancer recurrence.” She will share her findings with Cancer Care Nova Scotia’s Surgical Oncology Network, which ensures surgeons in the province are trained in the latest evidence-based techniques. Dr. Richardson’s research endeavours will soon earn her a Masters degree in community health and epidemiology. She was able to pursue this degree through the Department of Surgery’s Clinician Investigator Program. This is open to surgery residents who want to work towards a researchoriented graduate degree while they’re completing their residency training. “I want to be able to find the answers that will lead the way to improved surgical care for our patients,” Dr. Richardson says. “I see research as fundamental to my career as a surgeon.” 14 | Department of Surgery Re search Pr oduct i vi t y – Report from the Dal Surgery Research Office D al Surgery is charged with a series of formidable challenges. Not only must we deliver the highestquality clinical care, we must play a leadership role in defining what this means. This task demands constant questioning, discovery, innovation, and testing to determine what truly makes the most effective evidence-based care. And, to ensure that evidence continues to guide and refine clinical practice in the future, we must foster the next generation of researchers. Grant Capture in Millions 2006-2010 In addition to our dedication to research, we must devote ourselves to our stewardship of the next 18 16 generation of physicians and surgeons. We feel a deep sense of 14responsibility and commitment to transferring 12 our knowledge of skills, and clinical wisdom gained through experience, to our surgical residents and 10 8 undergraduate medical students. 6 4 2 By tracking our accomplishments in the areas of research productivity and teaching activities, we have 0 2006 2007 2008 2009 2010 established a concrete record of our performance in these vital domains. RESEARCH DELIVERABLES Peer-reviewed manuscripts: Our peer-reviewed track record establishes us as investigators, research teams and as an academic department of surgery. In 2010, we published 172 peer-reviewed manuscripts. Dal Surgery’s number of peerreviewed publications has steadily increased, as support for research within the department’s budget allows for investigatordriven research. Publications 180 160 140 120 100 80 60 40 20 0 2006 2007 2008 2009 2010 YEAR Abstracts and presentations: Abstracts are tied to presentations at national and international meetings. They remain the key to translating the latest discoveries or findings to new observers and other investigators. In 2010 our abstracts/presentations numbered 389. International 153 National 162 Local 74 Grant capture: In 2010, faculty in Dal Surgery were awarded 19 new grants, totalling $15,362,791. This influx of new grants brought the total number of grants—held by faculty as primary investigators, co-applicants or members of multi-institutional studies or teams—up to 85. The total value of these grants is $55,367,203. Grant Capture in Millions 2006-2010 18 16 14 12 10 8 6 4 2 0 2006 2007 2008 2009 2010 Dalhousie University | 15 Research grants fuel the engines of research here in Dal Surgery. They also stimulate the local economy by funding good-quality jobs. Dal Surgery research-driven programs employ more than 125 Nova Scotians, in such roles as research technician, analyst, research nurse, research coordinator, graduate student and administrative support. Participation in peer-review work: Taking part in peer-review work provides essential support to the wider academic enterprise, while raising the stature of the researchers involved. Our investigators give freely of their time to review research grant applications and manuscripts submitted for publication. Dal Surgery faculty members act as peer reviewers or editors of more than 40 high-quality journals. Dal Surgery Research Funds Clinical trials: Dal Surgery investigators and research support staff are currently engaged in more than 60 clinical trials. These rigourously designed and conducted studies often involve multiple centres across Canada 200,000.00 Programme 33 or around the world. 253,000.00 Resident 42 38,500.00 Bridge 6.4 52,000.00 Admin 8.6 Dal Surgery Fund: Our department continues to support the research efforts of our faculty 24,500.00Research promo 4.5 members and residents. This is an essential part of our mandate that serves to expand our research capacity and 32,000.00 Seed 5.5 productivity. In 2010 Dal Surgery invested $600,000.00 towards the research mission of the Department. 600,000.00 100 2010 Dal Surgery Research Fund Promotion and Publications 4% Administration 9% Seed Funding 6% Programme Support 33% Bridge Funding 6% Resident Research Support 42% Clinician Investigator Program: Supporting surgery residents’ research studies sets them on the path to becoming clinician scientists in their future careers. Such investigators are poised to ask the most clinically relevant questions and pursue research that makes significant impacts on patient care and outcomes. Dal Surgery embraces the multi-faceted role of the clinician scientist, both by recruiting these in-demand professionals, and by training the next generation of clinician scientists. Seven surgery residents were enrolled in our Clinician Investigator Program in 2010: Dr. Christine Herman Dr. Lindsay McDonald Dr. Scott Livingstone Dr. Matthew Smith Dr. Paul Yaffe Dr. Phillipe Magown Dr. Devon Richardson 16 | Department of Surgery E d u c ation Product ivi t y – Report from the Dal Surgery Education Office A group of dedicated faculty educators guide the teaching of residents and medical students in the Department of Surgery. All faculty members participate through teaching and mentoring, which results in an educational environment of the highest calibre. The Department of Surgery has residency training programs in six surgical specialties, which in 2010/11 totalled 85 residents and 15 fellows: Resident Programs Cardiac Surgery (4) General Surgery (31) Neurosurgery (8) Orthopaedics (20) Otolaryngology (12) Plastic Surgery (10) Fellowships in Subspecialties Cardiac Surgery (3) General Surgery (2) Orthopaedics (6) Otolaryngology (2) Plastic Surgery (2) Dal Surgery has a longstanding history of training its graduates to be qualified leaders in surgery. The Department’s faculty members are actively involved in the education and training of residents. Education programs include: Surgical Foundations Program: This program starts in July, and offers skills sessions for the PGY1s throughout the summer. The seminar series begins in September for PGY1s and PGY2s, which covers a range of topics outlined in the Royal College Objectives of Surgical Foundations Training. Skills sessions are also offered throughout the year as part of the Surgical Foundations Program. Hours taught by faculty for the Surgical Foundations Program: 50 HOURS Academic Half Days: Every residency program has a designated academic half day. The academic half days cover topics from the objectives of training provided by the Royal College for each specialty. Hours taught by faculty for Academic Half Days: 440 HOURS Skills Centre Teaching: The Skills Centre’s training equipment and models give residents and faculty the opportunity to practice new skills and techniques in a virtual OR setting. Training of manual skills is done using synthetic models, virtual reality simulation, cadaveric human tissue and animal tissue. Undergraduate Education: Faculty members are actively involved in undergraduate teaching including Med 1 and Med 2 Clinical Skills, Professional Competencies, Case Based Learning, and electives. Additionally, each third year clerk will rotate through the nine week surgical clerkship. Hours taught by faculty for Undergraduate Education: 1165 HOURS Clerkship Seminar Series: Dal Surgery faculty members are committed to undergraduate medical education. Faculty members prepare and deliver seminars based on the surgical clerkship objectives. Hours taught by faculty for the Clerkship Seminar Series: 192 HOURS Dalhousie University | 17 A pp end i x Publications 2010 Ahmed A, Ali IM, Ali IS, Cookey J. Simple techniques to manage the patent internal mammary artery in re-do cardiac surgery. Open Journal of Cardiovascular and Thoracic Surgery. 2010. 3:1-4. Imran S, Ransom T, Buth K, Clayton D, Al-Shaeri B, Ur E, Ali IS. Impact of admission serum glucose level on in-hospital outcomes following coronary artery bypass grafting surgery. Canadian Journal of Cardiology. 2010. 26(3): 151-54. Kalavrouziotis D, Buth K, Ali IS. Reply to Ngage. European Journal of Cardiothoracic Surgery. 2010. 37: 981-82. Kalavrouziotis D, Légaré JF, Baskett R, Dickieson A, Ali IM, Ali IS, Rapchuk I. A case of massive pulmonary embolism after cardiac surgery: the role of epicardial echocardiography. Journal of Cardiothoracic and Vascular Anesthesia. 2010. 24 (2): 309-31. Ouzounian M, Buth KJ, MacPherson C, Ali IM, Hirsch G, Ali IS. The impact of endoscopic vs open saphenous vein harvest techniques on outcomes following coronary artery bypass grafting. Annals of Thoracic Surgery. 2010. 89: 403-9. Ali IS. Insulin-induced myocardial protection: beyond metabolic modulation. World Journal of Cardiology. 2010. Ali IS. Impact of pre-operative and new-onset post-operative atrial fibrillation on outcomes of cardiac surgery. World Journal of Cardiology. 2010. Kiberd B, Skedgel C, Alwayn IP, Peltekian K. Simultaneous liver kidney transplantation: a medical decision analysis. Transplantation. 2010. Oct 20. Dols LF, Kok NF, Terkivatan T, Tran KT, Alwayn IP, Weimar W, Ijzermans JN. Optimizing left-sided live kidney donation: hand-assisted retroperitoneoscopic as alternative to standard laparoscopic donor nephrectomy. Transplant International. 2010. 1;23(4):358-63. Dols LF, Kok NF, Terkivatan T, Tran TK, d’Ancona FC, Langenhuijsen JF, Mertens Zur Borg R, Alwayn IP, Hendriks MP, Dooper IM, Weimar W, Ijzermans JN. Hand-assisted retroperitoneoscopic vs standard laparoscopic donor nephrectomy: HARP-trial. BMC Surgery. 2010. 10(1):11. Stevens MS, Legay D, Glazebrook MA, Amirault D. The evidence for hip arthroscopy: grading the current indications. Arthroscopy. 2010. 26-10:1370-83. patulous eustachian tube. Journal of Otolaryngology-Head and Neck Surgery. 2010. Jun: 39(3):259-68. Torbatian Z, Adamson R, Bance M, Brown JA. A split-aperture transmit beamforming technique with phase coherence grating lobe suppression. IEEE Trans Ultrason Ferroelectr Freq Control. 2010. Nov: 57(11):2588-95. Adamson RB, Bance M, Brown JA. A piezoelectric bone-conduction bending hearing actuator. Journal Acoustical Society of America. 2010. Oct: 128(4):2003-8. Deas RW, Adamson RB, Curran LL, Makki FM, Bance M, Brown JA. Audiometric thresholds measured with single and dual BAHA transducers: the effect of phase inversion. International Journal of Audiology. 2010. Dec: 49(12):933-9. Wang J, Menchenton T, Yin S, Yu Z, Bance M, Morris DP, Moore CS, Korneluk RG, Robertson GS. Over-expression of x-linked inhibitor of apoptosis protein slows presbycusis in C57BL/6J mice. Neurobiology Aging. 2010. Jul: 31(7):1238-49. Martin BJ, Buth KJ, Arora RC, Baskett R. Delirium as a predictor of sepsis in post-coronary after bypass grafting patients: a retrospective cohort study. Critical Care Medicine. 2010. 27;14(5): R171. Lala Y, Légaré JF, Baskett R. Clinical review of short-term ventricular assist device (VAD) use. Canadian Journal of Cardiology. 2010. Vol 26 Supple D, 61. Komatsu T, Coulter L, Henteleff H, Johnston M, Bethune D. Considering the feasibility of introducing nurse practitioners into Japanese thoracic services. Annals of Thoracic and Cardiovascular Surgery. 2010. Vol 16, No 4, 303-4. Bonjer J, et al. International Rectal Cancer Study Group (IRCSG). International preoperative rectal cancer management: staging, treatment and impact of multidisciplinary teams. World Journal Surgery. 2010. Nov: 34(11): 2689-700. McNeil M, Amoodi, Hosam, Brown T. Delayed presentation of hyoid strangulation fracture. The Journal of Otolaryngology . 2010. Oct. Brake M, Lee B, Savoury L, Cavanagh J, Burrage K, Smith T, Brown T. A survey of nasopharyngoscope decontamination methods in Canada. The Journal of Otolaryngology. 2010. Feb. Wilson JM, Blagovechtchenski E, Brownstone R. Genetically-defined inhibitory neurons in the mouse spinal cord dorsal horn: a possible source of rhythmic inhibition of motoneurons during fictive locomotion. Journal of Neuroscience. 2010. 30(3): 1137-1148. Pennings RJ, Morris DP, Clarke L, Allen S, Walling S, Bance M. Natural history of hearing deterioration in intracanalicular vestibular schwannoma. Neurosurgery. 2010. Nov 19. Brownstone R, Bui TV. Spinal interneurons providing input to the final common path during locomotion. Progressive Brain Research. 2010. 187: 81-95. Massoud S, Aiken SJ, Newman AJ, Phillips DP, Bance M. Sensitivity of the human binaural cortical steady state response to interaural level differences. Ear and Hearing. 2010. Aug 30. Brownstone R, Krawitz S, Jordan LM. Reversal of the late phase of spike frequency adaptation in cat spinal motoneurons during fictive locomotion. Journal Neurophysiology. 2010. Dec 22. McNeil ML, Gulliver M, Morris DP, Bance M. Quality of life improvement for BAHA users and their partners. Journal of Laryngology and Otology. 2010. Sep. Ref :103822. Buduhan, G, Orlina J, Louie B, Vallieres E, Aye R. Endoscopic and manometric position-related characteristics of the normal gastroesophageal junction. Surgical Endoscopy. 2010. Sep: 24(9): 2165-9. Amoodi H, Bance M, Thamboo A. Magnetic resonance imaging illustrating change in the Ostmann fat pad with age. Journal of Otolaryngology-Head and Neck Surgery. 2010. Aug: 39(4):440-1. Al-Habib AF, Attabib N, Ball J, Bajammal S, Casha S, Hurlburt RJ. Clinical predictors of recovery following blunt spinal cord trauma: systematic review. Journal of Neurotrauma. 2010. Apr 8. Pennings RJ, Ho A, Brown J, van Wijhe RG, Bance M. Analysis of vibrant sound-bridge placement against the round window membrane in a human cadaveric temporal bone model. Otology and Neurotology. 2010. Aug: 31(6):998-1003. Carnini A, Casha S, Yong VW, Hurlburt RJ, Braun JEA. Reduction of PrPc in human cerebrospinal fluid after spinal cord injury. Prion. 2010. Apr-Jun 4(2): 80-86. Bartlett C, Pennings R, Ho A, Kirkpatrick D, van Wijhe R, Bance M. Simple mass loading of the tympanic membrane to alleviate symptoms of Casha S, Christie S. A systematic review of intensive cardiopulmonary management after spinal cord injury. Journal of Neurotrauma. 2010. Apr. 18 | Department of Surgery McMorland G, Suter E, Casha S, du Plessis SJ, Hurlbert RJ. Manipulation or microdiskectomy for sciatica? A prospective randomized controlled pilot study. Journal of Manipulative and Physiological Therapeutics. 2010. Oct: 33(8): 576-84. Kwon BK, Casha S, Hurlbert RJ, Yong VW. Review: Inflammatory and structural biomarkers in acute traumatic spinal cord injury. Clinical Chem Lab Medicine. 2010. Dec 23. T Xue M, Mikliaeva E, Casha S, Zygun D, Demchuk A, Yong VW. Improving outcomes of neuroprotection by minocycline: guides from cell culture and intracerebral hemorrhage in mice. American Journal of Pathology. 2010. 176(3) 1193-202. Christie S, Thibault-Halman G, Casha S. Acute pharmacological DVT prophylaxis following SCI. Journal of Neurotrauma. 2010. Aug: 27: 1-6. Thibault-Halman G, Casha S, Singer S, Christie S. Acute management of nutritional demands following spinal cord injury. Journal of Neurotrauma. 2010. 27;1-11. Kiberd MB, MacAulay RJ, Christie S. Skull base hemangiopericytoma: treatment options. Canadian Journal of Neurological Sciences. 2010. 37(1): 131-124. Arnason T, Clarke DB, Imran SI. Thyroid-stimulating hormone secreting pituitary adenoma. Canadian Medical Association Journal. 2010. In Press. O’Reilly AM, Currie RW, Clarke DB. HspBI (Hsp 27) expression and neuroprotection in the retina. Molecular Neurobiology. 2010. 42:124-132. McGrath BM, Maloney WJ, Wolfsberger S, Hill R, Massoud E, Imran SI, Clarke DB. Carotid artery visualization during anterior skull base surgery: a novel protocol for neuronavigation. Pituitary. 2010. 13(3):215-22. Ironside S, Gonzalez F, Sadler M, Rahey S, Clarke, DB. Long-term effectiveness of vagus nerve stimulation for refractory epilepsy. The Journal of the Canadian Neurological Sciences Federation. 2010. Imran SA, Pelkey M, Clarke DB, Clayton D, Trainer P, Ezzat Shereen. Spuriously elevated serum IGF-1 in individuals with delayed puberty - a diagnostic pitfall. International Journal of Endocrinology. 2010. DOI 10.1155, 370692. PRAISE Investigators (Coles C). PRevalance of Abuse and Intimate Partner Violence Surgical Evaluation (PRAISE): Rationale and design of a multi-centre cross-sectional study. 2010. BMC Musculoskeletal Discord. 23: 11-77. Dunbar MJ. The proximal modular neck in THA: a bridge too far: Affirms. Orthopaedics. 2010. Sep. Padmos JD, Duchesne P, Dunbar MJ, Zhang P. Gold nanoparticles on titanium and interaction with prototype protein. Journal of Biomedical Materials Research. 2010. Part A, 95A: 146–155. Sanmartin C, McGrail K, Dunbar MJ, Bohm E. Using population data to measure outcomes of care: the case of hip and knee replacements. Statistics Canada, Catalogue. 2010. no. 82-003-XPE- Health Reports, Vol. 21, no 2, June. Wilson DAJ, Dunbar MJ, Amirault JD, Farhat Z. Early failure of a modular femoral neck total hip arthroplasty component: a case report. Journal of Bone and Joint Surgery AM. 2010. 92: 1514-1517. El-Hawary R, Maclellan B, Cook C, Leahey L, Hyndman JC. Extension type II supracondylar humerus fractures: a radiographic outcomes study of closed reduction and cast immobilization. Journal of Paediatric Orthopaedics. 2010. MacNeil J, Francis J, El-Hawary R. A systematic review of rigid, locked, intramedullary nail insertion sites and avascular necrosis of the femoral head in the skeletally immature. Journal of Paediatric Orthopaedics. 2010. Lewington M, El-Hawary R. Legge Calve-Perthes Disease in a patient with Albright’s hereditary osteodystrophy: a case report. Journal of Bone & Joint Surgery. 2010. Feb: 92(2):450-5. Gould J, Ellsmere J, Fanellie R, Hutter M, Jones S, Pratt J, Schauer P, Schirmer B, Schwaitzberg S, Jones DB. Panel report: best practices for the surgical treatment of obesity. Surgical Endoscopy. 2010. Dec 7. Soundararajan P, Fawcett JP, Rafuse V. Directed growth of postural motor axons requires activation of the MAPK/ERK signaling pathway. Journal of Neuroscience. 2010. 30:6595-6606. Richier L, Williton K, Clattenburg L, Colwill K, O’Brien M, Tsang C, Kola A, Zinck N, Metalnikov P, Trimble WS, Krueger S, Pawson T, Fawcett JP. NOS1AP associates with scribble and regulates dendritic spine development. Journal of Neuroscience. 2010. 30:4796- 4805. Glazebrook M. End-stage ankle arthritis: magnitude of the problem and solutions. Instructional Course Lecture. 2010. 59:359-65. Slobogean GP, Younger A, Apostle KL, Marra CA, Wing K, Penner M, Daniels T, Glazebrook M. Preference-based quality of life of endstage ankle arthritis treated with arthroplasty or arthrodesis. Foot Ankle International. 2010. 31-7:563-6. Chiodo CP, Glazebrook M, Bluman EM, Cohen BE, Femino JE, Giza E, Watters WC, Goldberg MJ, Keith M, Haralson RH, 3rd, Turkelson CM, Wies JL, Hitchcock K, Raymond L, Anderson S, Boyer K, Sluka P. American Academy of Orthopaedic Surgeons clinical practice guideline on treatment of Achilles tendon rupture. Journal Bone Joint Surgery American. 2010. 92-14:2466-8. Chiodo CP, Glazebrook M, Bluman EM, Cohen BE, Femino JE, Giza E, Watters WC, Goldberg MJ, Keith M, Haralson RH, 3rd, Turkelson CM, Wies JL, Raymond L, Anderson S, Boyer K, Sluka P. Diagnosis and treatment of acute Achilles tendon rupture. Journal American Academy of Orthopaedic Surgeons. 2010.18-8:503-10. Krause FG, Di Silvestro M, Penner MJ, Wing KJ, Glazebrook M, Daniels TR, Lau JT, Stothers K, Younger AS. Inter- and intraobserver reliability of the COFAS end-stage ankle arthritis classification system. Foot Ankle International. 2010. 31-2:103-8. Devitt J, King C, Lee T, Hancock Friesen C. Early innate immune events induced by prolonged cold ischemia exacerbate allograft vasculopathy. Journal of Cardiothoracic Surgery. 2010. Robertson M, Liu D, Burton H, Fleming K, Jackson S, Warren A, Hancock Friesen C. Follow up of tetralogy of fallout patients: tertiary center versus satellite clinic. Cardiology in the Young. 2010. Jun 10:141. Conte J, Weissman N, Dearani JA, Bavaria J, Heimansohn D, Dembitsky W, Doyle D, Hancock Friesen C. A North American, prospective, multicenter assessment of the mitroflow aortic pericardial prosthesis. Annals of Thoracic Surgery. 2010. 90:144-52. King C, Devitt JJ, Lee T, Hancock Friesen C. Neutrophil mediated medial smooth muscle cell loss precedes allograft vasculopathy. Journal of Cardiothoracic Surgery. 2010. Jun 22: 5:52. Robertson M, Liu D, Hancock Friesen C. Division of the inferior vena cava for access to post-repair pulmonary venous obstruction. Annals of Thoracic Surgery. 2010. 89(4):1310-11. Shahanavaz A, Taylor SM, Trites J, Harris J, Seikaly H, Henry E, Hart R. The double fat plane of the forearm: implications for the microvascular surgeon. Journal of Otolaryngology –Head and Neck Surgery. 2010. Jun: 39(3):288-91. Dalhousie University | 19 Brace M, Taylor SM, Bethune D, Attia E, Trites J, Hart R. Endoscopic stapling versus external transcervical approach for the treatment of Zenkers diverticulum. Journal of Otolaryngology –Head and Neck Surgery. 2010. Feb: 1;39(1):102-6. Macdonald K, Taylor SM, Cavanagh J, Trites J, Bullock M, Hart R. Level VI node size as a predictor of malignancy in papillary thyroid cancer. Journal of Otolaryngology–Head and Neck Surgery. 2010. Apr: 39(2):136-41. Amoodi HA, Makki F, Taylor SM, Trites J, Bullock M, Hart R. Lateral ectopic thyroid goiter with a normally located thyroid. Thyroid. 2010. Feb: 20(2):217-20. Marcato P, Dean C, Pan D, Araslanova R, Gillis M, Joshi M, Helyer L, Pan L, Leidal A, Giacomantonio CA, Lee P. Aldehyde dehydrogenase activity of breast cancer stem cells is primarily due to isoform ALDH1A3 and its expression is predictive of metastasis. Stem Cells. 2010. Nov 23. Coburn N, Lourenco L, Rossi S, Gunraj N, Mahar A, Helyer L, Law C, Rabeneck L, Paszat L. Management of gastric cancer in Ontario. Journal Surgical Oncology. Jul 1: 102(1): 54-63. Wright FC, Chakraborty A, Helyer L, Moravan V, Shelby D. Predictors of survival in patients with a non-curative stage IV cancer and malignant bowel obstruction. Journal of Surgical Oncology. 2010. 1: 101(5): 425-29. Helyer L, Varnic M, Le L, Leong W, McCready D. Obesity is a risk factor for developing postoperative lymphedema in breast cancer patients. Breast Journal. 2010. Jan-Feb: 16(1): 48-54. Latosinsky S, Thirlby R, Urbach D, Henteleff, H, for members of the Evidence Based Reviews in Surgery Group. Canadian Association of General Surgeons and American College of Surgeons Evidence Based Reviews in Surgery. 32. Canadian Journal of Surgery. 2010. Vol 53, No. 1 Lee D, Buth K, Martin B, Yip A, Hirsch G. Frail patients are at increased risk for mortality and prolonged institutional care after cardiac surgery. Circulation. 2010. Mar 2: 121(8): 973-8. Hassan A, Newman A, Ko DT, Rinfret S, Hirsch G, Ghali W, Tu JV. Increasing rates of angioplasty vs bypass surgery in Canada 1994-2005. American Heart Journal. 2010. Nov: 160(5): 958-65. Herman C, Buth K, Kent B, Hirsch G. Clopidogrel increases blood transfusion and hemorrhagic complications in patients undergoing cardiac surgery. Annals of Thoracic Surgery. 2010. Feb: 89(2): 397-402. Hong P, Smith N, Johnson L, Corsten G. A randomized doubleblind controlled trial of phosphorylcholine-coated tympanostomy tube vs standard tympanostomy tube in children with recurrent acute and chronic otitis media. Laryngoscope. 2010. August. Hilchie A, Furlong S, Sutton K, Richardson A, Robichaud MR, Giacomantonio C, Ridgway N, Hoskin D. Curcumin-induced apoptosis in PC3 prostate carcinoma cells is caspase-independent and involves cellular ceramide accumulation and damage to mitochondria. Nutrition and Cancer. 2010. Apr: 62(3): 379-89. Watson J, Hill R, Yaffe P, Greenshields A, Walsh M, Lee P, Giacomantonio C, Hoskin D. Curcumin causes superoxide anion production and p53-independent apoptosis in human colon cancer cells. Cancer Letter. 2010. Nov: 1:297(1): 1-8. Watson J, Greenshields A, Hill R, Hilchie A, Lee P, Giacomantonio C, Hoskin D. Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and surviving expression and Akt signaling. Molecular Carcinology. 2010. Jan: 49(1): 13-24. Komatsu T, Henteleff H. Colopleural fistula with atypical presentation as a complication of ciaphragmatic hernia repair. Annals of Thoracic Surgery. 2010. 90: 662-3. Furlong S, Mader J, Hoskin D. Bovine lactoferricin induces caspaseindependent apoptosis in human B-lymphoma cells and extends the survival of immune-deficient mice bearing B-lymphoma xenografts. Experimental Molecular Pathology. 2010. Jun: 88(3): 371-5. Neumayer L, Maraccio M, Visser B, Henteleff H, for Members of the Evidence Based Reviews in Surgery Group. Canadian association of general surgeons and American college of surgeons evidence based reviews in surgery. Journal of the American College of Surgeons. 2010. Vol 210, No 3. Conrad D, Furlong S, Doucette C, West K, Hoskin D. The Ca(2+) channel blocker flunarizine induces caspase-10-dependent apoptosis in Jurkat T-leukemia cells. Apoptosis. 2010. May: 15(5): 597-607. Kirkpatrick A, Britt L, Kortbeek K, Tallon J, Henteleff H, for members of the Evidence Based Reviews in Surgery Group. Canadian Association of General Surgeons and American College of Surgeons Evidence Based Reviews in Surgery. Journal of the American College of Surgeons. 2010. Vol 210, No 6. Brasel K, Gottesman L, Vasilevsky C, Hentellef H, for members of the Evidence Based Reviews in Surgery Group. Canadian Association of General Surgeons and American College of Surgeons Evidence Based Reviews in Surgery. Journal of the American College of Surgeons. 2010. Vol 211, No 3. Mastracci T, Aarts M, Cassivi S, Garcia S, McLean R, McFalls E, Henteleff H, for members of the Evidence Based Reviews in Surgery Group. Canadian Association of General Surgeons and American College of Surgeons Evidence Based Reviews in Surgery. 34. Canadian Journal of Surgery. 2010. Vol 53, No 5. Chaudhury P, Marshall J, Solomkin J Henteleff H, for members of the Evidence Based Reviews in Surgery Group. Canadian Association of General Surgeons and American College of Surgeons Evidence Based Reviews in Surgery. 35. Canadian Journal of Surgery. 2010. Vol 53, No 6. Ouzounian M, Hassan A, Yip AM, Buth KJ, Baskett R, Ali IS, Hirsch G. The impact of sequential grafting on clinical outcomes following coronary artery bypass grafting. European Journal Cardiothoracic Surgery. 2010. Nov: 38950:579-84. Forward N, Furlong S, Yang Y, Lin T, Hoskin D. Signaling through TLR7 enhances the immunosuppressive activity of murine CD4+CD25+ T regulatory cells. Journal of Leukocyte Biology. 2010. Jan: 87(1): 117-25. Watson J, Yaffe P, Walsh M, Giacomantonio C, Hoskin D. Oncogenic BRAF in cutaneous melanoma: Mutational status and implications for targeted therapy. Canadian Journal of Pathology. 2010. 2:27-33. Borugian M, Robson P, Fortier I, Parker L, McLaughlin J, Knoppers B, Bedard K, Gallagher R, Sinclair S, Ferretti V, Whelan H, Hoskin D, Potter JD. The Canadian Partnership for Tomorrow Project: building a panCanadian research platform for disease prevention. Canadian Medical Association Journal. 2010. 182: 1197-1201. Comstock S, Cook C, Leahey L, El-Hawary R, Hyndman J. Posterior kyphectomy for myelomeningocele with anterior placement of fixation: a retrospective review. Clinical Orthopaedics and Related Research. 2010. Sporici R, Issekutz TB. CXCR3 blockade inhibits T-cell migration into the CNS during EAE and prevents development of adoptively transferred, but not actively induced disease. European Journal of Immunology. 2010. Oct: 40(10): 2751-61. Shehata N, Palda V, Bowen T, Haddad E, Issekutz TB, Maser B, Schellenberg R, Warrington R, Easton D, Anderson D, Hume H. The use of immunoglobin therapy for patients with primary immune deficiency: an evidence-based practice guideline. Transfusion Medicine Reviews. 2010. Jan: 24 Suppl 1: S28-50. 20 | Department of Surgery Dokouhaki P, Han M, Joe B, Li M, Johnston MR, Tsao MS, Zhang L. Adoptive immunotherapy of cancer using ex vivo expanded human T cells: a new approach. Cancer Letters. 2010. May 25. Anraku M, Tagawa T, Wu L, Yun Z, Keshavjee S, Zhang L, Johnston MR, dePerrot M. Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignant mesothelioma. Journal of Immunology. 2010.185:956-66. Brenner DR, Hung RJ, Tsao MS, Shepherd FA, Johnston MR, Narod S, Rubenstein W, McLaughlin JR. Lung cancer risk in never-smokers: a population-based case-control study of epidemiologic risk factors. BMC Cancer. 2010. 10:285. Jaskolka JD, Kachura JR, Hwang DM, Tsao MS, Waddell TK, Asch MR, Darling GE, Johnston MR. Pathologic assessment of radiofrequency ablation of pulmonary metastases. Journal of Vascular Interventional Radiology. 2010. 21: 1689-96. Richardson DP, Porter G, Johnson PM. Self-reported patterns of rectal cancer care among general surgeons in Canada. Canadian Journal of Surgery. 2010. 53 (suppl):S97. Richardson DP, Porter G, Johnson PM. A population-based description of the presentation and management of recurrent rectal cancer. Canadian Journal of Surgery. 2010. 53 (suppl):S65. Hart-Matyas M, Nejat S, Jordan JL, Hirsch G, Lee T. IFN-gamma and fas/fasL pathways cooperate to induce medical cell loss and neointimal lesion formation in allograft vasculopathy. Transplant Immunology. 2010. Feb: 22(3-4): 157-164. Kulkarni AV, Shamas I, Cochrane DD, McNeely PD. Does treatment with endoscopic third ventriculostomy result in less concern among parents of children with hydrocephalus? Child’s Nervous System. 2010. 26(11): 1529-34. Kulkarni AV, Shamas I, Cochrane DD, McNeely PD. Quality of life after endoscopic third ventriculostomy and cerebrospinal fluid shunting: an adjusted multivariable analysis in a large cohort. Journal of Neurosurgery: Pediatrics. 2010. 6(1): 11-16. Baghbaderani B, Mukhida K, Sen A, Kallos M, Hong M, Mendez I, Behie LA. Bioreactor expansion of human neural precursors cells in serum-free media retains neurogenic potential. Biotechnology and Bioengineering. 2010. 105(4) 823-33. Baghbaderani BA, Mukhida K, Hong M, Mendez I, Behie LA. Overcoming bioengineering problems for human neural precurser cell expansion in preparation for clinical trials. Stem Cell. 2010. In press. Atlaf A, Ellsmere J, Bonjer H, Klassen D. Hand-assisted laparascopic splenectomy compared to conventional laparoscopic splenectomy. Canadian Journal of Surgery. 2010. Alsohaibani F, Porter G, Al-Ashgar H, Walsh M, Berry R, Molinari M, Peltekian KM. Comparison of cancer care for hepatocellular carcinoma at two tertiary-care referral centers from high and low endemic regions for viral hepatitis. Journal Gastrointestinal Cancer. 2010. Sep. Biosvert R, Bethune D, Action D, Klassen D. Bilateral Killan-Jamieson diverticula: A case report and literature review. Canadian Journal of Gastroenterology. 2010. Mar: 24(3): 173-4. Molinari M, Renfrew PD, Petri N, Walsh MJ, Peltekian K, Alwayn I. The predictive mortality of MELD and MELDNa is underestimated for patients living in rural areas. Transplant International. 2010. Sep. Gelinas L, Falkenham A, Oxner A, Sopel M, Lee TDG, Légaré JF. Human peripheral blood monocytes produce IL-6 in response to AngII. Journal Renin Angiotensin System. 2010. Sharma C, Eltawil K, Renfrew PD, Walsh MJ, Molinari M. Advances in diagnosis, treatment and palliation of pancreatic carcinoma: 1990-2010. World Journal of Gastroenterology. 2010. Sopel M, Lee TDG, Légaré JF. Myocardial fibrosis in response to angiotensin II is preceded by the recruitment of mesenchymal progenitor cells. Laboratory Investigations. 2010. Aljiffry M, Renfrew PD, Walsh MJ, Lareya M, Molinari M. Dominant bile duct strictures in patients with primary sclerosing cholangitis. Journal of Hepatobiliary and Pancreatic Surgery. 2010. Elghobary T, Légaré JF. What has happened to multiple arterial grafting in coronary artery bypass grafting surgery? Expert Review of Cardiovascular Therapy. 2010. Aug: 8(8):1099-105. Morris DP, Van Wijhe RG. Cholesteatoma in three dimensions: a teaching tool and an aid to improved pre-operative consent. Journal Laryngology Otology. 2010. Feb: 124(2):126-31. Sopel M, Ma I, Gelinas L, Oxner A, Myers T, Légaré JF. Integrins and monocyte migration to the ischemic myocardium. Journal of Investigative Surgery. 2010. Apr: 23(2):79-86. O’Blenes M, Lee C, Walsh JP, Morris SF. An unusal case of turban tumor syndrome treated with total scalp excision and advancement flap and skin graft reconstruction. Annals of Plastic Surgery. 2010. 65(1); 107-109. Hawkins JL, Myers GJ, Légaré JF, Swyer W. Arterial filter bypass loop: what occurs during cardiopulmonary bypass, and are there potential patient implications? Perfusion Journal. JECT 2010; 42: 71-74. Morris SF, Tang M, Almutairi K, Geddes C, Yang D. The anatomic basis of perforator flaps. Annals of Plastic Surgery. 2010. Oct: 37(4); 553-570. Légaré JF, Li D, Buth KJ. How established wait time standards significantly underestimate wait times for cardiac surgery. Canadian Journal of Cardiology. 2010. Jan: 26(1):e17-21. Légaré JF, Baskett RJF. Clinical review of short-term Ventricular Assist Device (VAD) use. Canadian Journal of Cardiology. 2010. Oct: Vol 26 supple D, 61. Freed DH, Henzler D, White CW, Fowler R, Zarychanski R, Hutchison J, Arora RC, Manji RA, Légaré JF, Drews T, Veroukis S, Kesselman M, Guerguerian AM, Kumar A, The Canadian Critical Care Trials Group. Extracorporeal lung support for patients who had severe respiratory failure secondary to influenza A (H1N1) 2009 infection in Canada. Canadian Journal of Anaesthesia. 2010. Jan 16. Tang M, Ding M, Almutari K, Morris SF. The three dimensional angiography of the submental artery perforator flap. Journal of Plastic, Reconstructive & Aesthetic Surgery. 2010. Sep 24. Alqahtani M, Howlett A, Morris SF. Immediate great toe to hand transfer for reconstruction of amputated thumb. Journal of Reconstructive Microsurgery. 2010. Tang M, Morris SF. Three-dimensional angiography of the deep circumflex iliac artery osteocutaneous perforator flap. A cadaver study. In press. Plastic and Reconstructive Surgery. 2010 Appleton S, Ngan A, Kent B, Morris SF. Risk factors influencing transfusion rates in DIEP flap breast reconstruction. Plastic Reconstructive Surgery. 2010. Dalhousie University | 21 Almutairi K, Tang M, Morris SF. Three-dimensional anatomical study of the vascular supply to the tensor fascia lata and overlying skin. Canadian Journal of Plastic Surgery. 2010. 18(2), 47. Mendez AI, Hart R, Bullock MJ, Taylor SM. Undifferentiated high-grade pleomorphic sarcoma of the face. Journal of Otolaryngology–Head and Neck Surgery. 2010. Oct: 39(5):E61-62. Bezuhly M, Cullen R, Esmon C, Morris SF, West K, Johnston B, Liwski R. Role of activated protein C and its receptor in inhibition of melanoma metastasis. Canadian Journal of Plastic Surgery. 2010. 18(2), 51. O’Brien JD, Belyea J, Hart R, Trites J, Taylor SM. CO2 laser resection of a supraglottic rhabdomyosarcoma: case report and review. Dalhousie Medical Journal. 2010. Spring 37(1):26-28. Chung B, Morris SF. Factors affecting privatization for consultation regarding carpal tunnel syndrome. Canadian Journal of Plastic Surgery. 2010. 18(2), 71. McNeil ML, Bullock MJ, Trites J, Hart R, Taylor SM. Oncocytic lipoadenoma of the parotid gland with sebaceous differentiation in a 73-year-old male. Journal of Otolaryngology–Head and Neck Surgery. 2010. Oct: 39(5):E48-50. Appleton SE, Ngan A, Kent B, Morris SF. Risk factors influencing transfusion rates in DIEP flap breast reconstruction. Canadian Journal of Plastic Surgery. 2010. 18(2), 16. Arnason T, Hart R, Taylor SM, Trites J, Nasser J, Bullock MJ. Diagnostic accuracy and safety of fine-needle aspiration biopsy of the parapharyngeal space. Diagnostic Cytopathology. 2010. Nov 9. O’Blenes S, LI A. Chen R, Arora R, Horackova M. Engraftment is optimal when myoblasts are replanted early. The role of hepatocyte growth factor. Annals of Thoracic Surgery. 2010. Mar: 89(3): 829-35. Sader C, Hart R, Trites J, Rigby M, Phillips T, Taylor SM. The communicating vein in the radial forearm free flap. Plastic and Reconstructive Surgery. 2010 Aug: 126(2):105-107. Vyas T, Hart R, Trites J, Phillips T, Archibald K, Phillips J, Taylor SM. Use of complementary medicine in head and neck cancer patients. Head and Neck. 2010. Jun: 32(6):793-9. Sader C, Hart R, Trites J, Phillips T, Rigby M, Taylor SM. Fat graft pedicle stabilization in head and neck microvascular reconstruction. Plastic and Reconstructive Surgery. 2010. Mar: 125(3):893-5. O’Blenes S, Hancock Friesen C, Ali A, Howlett S. Protecting the aged heart during cardiac surgery: the potential benefits of delNido cardioplegia. Journal of Thoracic and Cardiovascular Surgery. 2010. Jul 23. Makki F, Williams B, Rajaraman M, Hart R, Trites J, Brown T, Taylor SM. Current practice patterns in the management of glottic cancer in Canada: results of a national survey. The Journal of Otolaryngology. 2010. Dec. Porter G, Urquhart R, Bu J, Johnson P, Grunfeld E. The impact of audit and feedback on nodal harvest in colorectal cancer. BMC Cancer. 2010. In press. Taylor SM. Letter to the editor. Oral Oncology. 2010. Jun. Alsohaibani F, Porter G, Al-Ashgar H, Walsh MJ, Berry R, Molinari M, Peltekian KM. Comparison of cancer care for hepatocellular carcinoma at two tertiary-care referral centers from high and low endemic regions for viral hepatitis. International Journal of Gastrointestinal Cancer. 2010 In Press Holmes M, Porter G, Tarasuk J, Sullivan J, Trudeau M, Bodie K. Process analysis and reorganization in three chemotherapy outpatient clinics. Healthcare Quarterly. 2010. 13:48-55. Vickers M, Samson B, Colwell B, Cripps C, Jalink D, El-Sayed S, Chen E, Porter G, Goel R, Villeneuve J, Sundaresan S, Asselah J, Biagi J, Jonker D, Dawson L, Letourneau R, Rother M, Maroun J, Thirlwell M, Hussein M, Tehfe M, Perrin N, Michaud N, Hammad N, Champion P, Rajan R, Burkes R, Barrette S, Welch S, Yarom N, Asmis T. Eastern Canadian Colorectal Cancer Consensus Conference: setting the limits of resectable disease. Current Oncology. 2010. 17:70-77. McConnell Y, Inglis KM, Porter G. Timely access and quality of care in colorectal cancer: are they related? International Journal Health Care. 2010. 22:219-28. PRAISE Investigators, Bhandari M, Sprague S, Dosanjh S, Wu V, Schemitsch EH. Prevalance of Abuse and Intimate Partner Violence Surgical Evaluation (PRAISE): Rationale and design of a multi-center crosssectional study. BMC Musculoskeletal Disorders. 2010. Apr: 23;11:77. Rutherford DJ, Hubley-Kozey CL, Stanish W. The neuromuscular demands of altering foot progression angle during gait in asymptomatic individuals and those with knee osteoarthritis. Osteoarthritis and Cartilage. 2010. 18: 654-661. Yepes H, Tang M, Geddes C, Glazebrook M, Morris S, Stanish W. Digital vascular mapping of the integument about the Achilles tendon. Journal of Bone and Joint Surgery. 2010. 92:1215-1220. Rutherford D, Hubley-Kozey CL, Stanish W. The neuromuscular demands of altering foot progression angle during gait in asymptomatic individuals and those with knee osteoarthritis. Osteoarthritis and Cartilage. 2010. 18(5):654-61. Sowerby LJ, Taylor SM, Moore CC. The double hatchet flap: a workhorse in head and neck local flap reconstruction. Archives of Facial Plastic Surgery. 2010. May-Jun: 12(3):198-201. Taylor SM. Multidose of restylane for facial augmentation. Archives of Facial Plastic Surgery. 2010. Nov-Dec: 12(6):433-4. Taylor SM, Drover C, Maceachern R, Bullock M, Hart RD, Psooy B, Trites J. Is preoperative ultrasonography accurate in measuring tumor thickness and predicting the incidence of cervical metastasis in oral cancer? Oral Oncology. 2010. Jan: 46(2010): 38-41. Amoodi HA, Makki FM, Taylor MS, Bullock MJ, Hart RD, Trites J. Synchronous thyroid/parathyroid carcinoma. Journal of Otolaryngology –Head and Neck Surgery. 2010. Oct: 39(5):E42-7. Valani R, Hancock BJ, Grant V, Yanchar N. The development of a national pediatric trauma curriculum. Medical Teacher. 2010. 32(3):e115-9. Oliveira C, Himidan S, Pastor AC, Nasr A, Manson D, Taylor G, Yanchar N, Brisseau G, Kim PC. Discriminating preoperative features of pleuropulmonary blastomas (PPB) from congenital cystic adenomatoid malformations (CCAM): a retrospective, age-matched study. European Journal of Pediatric Surgery. 2010. Nov 22. Hameed SM, Schuurman N, Razek T, Boone D, Van Heest R, Taulu T, Lakha N, Evans DC, Brown DR, Kirkpatrick AW, Stelfox HT, Dyer D, van Wijngaarden-Stephens M, Logsetty S, Nathens AB, Charyk-Stewart T, Rizoli S, Tremblay LN, Brenneman F, Ahmed N, Galbraith E, Parry N, Girotti MJ, Pagliarello G, Tze N, Khwaja K, Yanchar N, Tallon JM, Trenholm JA, Tegart C, Amram O, Berube M, Hameed U, Simons RK. Access to trauma systems in Canada. Journal of Trauma. 2010. 69(6):1350-1361. Pike I, Piedt S, WardaL, Yanchar N, MacArthur C, Babul S, MacPherson A. Developing injury indicators for Canadian children and youth: a modified-Delphi approach. Injury Prevention. 2010. 16:154-160. 22 | Department of Surgery Abstracts & Presentations 2010 Ali IM, Carver D. The role of the pulmonary artery catheter (Swan– Ganz) in the early diagnosis of post-cardiac surgery right ventricular dysfunction. The 59th International Congress of the European Society of Cardiovascular Surgery. Ali IM, Fomenko A. Avoidance of fibrillation /defibrillation testing at the time of internal defibrillator insertion: Is it safe? The 59th International Congress of the European Society of Cardiovascular Surgery. Ali IS. Update on the STITCH trial: Should the door remain open? Canadian Society of Cardiac Surgeons. Michler R, Pohost GM, Wrobel K Ali IS (STICH Investigators). Influence of left ventricular volume reduction on outcome after coronary artery bypass grafting with or without surgical ventricular restoration. American College of Cardiology. Bance M. Superior canal dehiscence. Otology on the Nile, Egyptian Otolaryngology Society. Bance M. Bilateral cochlear implants. Otology on the Nile, Egyptian Otolaryngology Society. Bance M. BAHA mini-course. Otology on the Nile, Egyptian Otolaryngology Society. Bance M. Bone conduction hearing devices. 11th International Conference on Cochlear Implants and Other Auditory Implantable Technologies. Bance M. Bone conduction hearing aids. Annual Meeting, Canadian Association of Speech Language Pathologists and Audiologists. Bance M. Eustachian tube dysfunction. Annual Meeting, Canadian Association of Speech Language Pathologists and Audiologists. Bance M. Vertigo assessment. Annual Meeting, Canadian Association of Speech Language Pathologists and Audiologists. Bance M. Future imaging technologies for the temporal bone. OtologyNeurotology Days. Ouzounian M, Buth K, Ali IS. Does preoperative angiotensin converting enzyme inhibitor use impact the outcomes of CABG surgery? Canadian Cardiovascular Conference. Bance M. Cartilage tympanoplasty. Otology-Neurotology Days. Savage K, Lee T, Alwayn I. Matrix metalloproteinase-9 is a potential target for therapies aimed at reducing ischemia/reperfusion injury in the liver. 45th Annual Congress of the European Society for Surgical Research. Bance M. Bone conduction hearing. Otology-Neurotology Days. Savage K, Lee T, Alwayn I. In vitro silencing of MMP-9 may alleviate hepatic IR injury. 16th Annual Congress of the International Liver Transplant Society. Bance M. Invited panelist: Ossiculoplasty. Otology-Neurotology Days. Livingstone S, Savage K, Alwayn I. Optimizing steatotic livers for transplantation using cell-penetrating HEM oxygenase protein. 61st Annual Meeting, American Association for the Study of Liver Diseases. Bance M. Middle ear reflectance in various middle disease states. 2nd Pan-American/Iberian Meeting on Acoustics. Bance M. Combining auditory and tactile inputs to create a sense of auditory space. 2nd Pan-American/Iberian Meeting on Acoustics. Bance M. Miniature, ultrasonic transcutaneous energy transmission system for powering implantable medical devices. 2nd Pan-American/ Iberian Meeting on Acoustics. Bance M. High-frequency ultrasound Doppler velocimetry measurements of intracochlear structures in human temporal bones. 2nd Pan-American/Iberian Meeting on Acoustics. Bance M. Microanatomy of the middle ear. Otology-Neurotology Days. Bance M. Invited panelist: Revision stapedectomy. Otology-Neurotology Days. Bance M. Future trends in otology. 2nd David Tomlinson Visiting Professor, University of Toronto Department of Otolaryngology. Bance M. Bone conduction mechanics. 2nd David Tomlinson Visiting Professor, University of Toronto Department of Otolaryngology. Bance M. Future otologic evaluation. Visiting Professor, University of Western Ontario, Grand Rounds. Baskett R. LVAD treatment: An overview of our clinical experience for acute and chronic heart failure. Atlantic Canadian Cardiovascular Congress. Baskett R. The Levitronix short-term ventricular assist device. Annual Meeting, Canadian Society of Cardiac Surgeons. Baskett R. Long-term ventricular assist device experience and management. Annual Meeting, Canadian Society of Cardiac Surgeons. Baskett R. The Levitronix VAD: The Canadian Experience. Edmonton AB. Bance M. Three-dimensional laser Doppler vibrometry of the dry human skull. 2nd Pan-American/Iberian Meeting on Acoustics. Brown T. Chair, laryngology forum discussion. 64th Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Bance M. Lumped parameter mechanical model of tensor tympani muscle contraction of the middle ear. 2nd Pan-American/Iberian Meeting on Acoustics. Brown T. Chair, paper session for laryngology. 64th Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Bance M. 3D skull vibrations in bone conduction hearing. 11th International Conference on Cochlear Implants and Other Auditory Implantable Technologies. Bance, M. Cochlear implants in the presence of acoustic neuromas: another treatment option. 11th International Conference on Cochlear Implants and Other Auditory Implantable Technologies. Bance M. Ossiculoplasty and middle ear mechanics. Otology on the Nile, Egyptian Otolaryngology Society. Bance M. New otologic imaging techniques. Otology on the Nile, Egyptian Otolaryngology Society. Hilal A, Makki F, Taylor SM, Trites J, Hart RD, Brown T. Accuracy of laryngoscopic photodocumentation in establishing the diagnosis of early laryngeal cancer. Annual Otolaryngology Research Day, Dalhousie University. Brown T. Laryngeal papillomatosis: Virology and transmission. 64th Annual Meeting, Canadian Society of Otolaryngology, Head & Neck Surgery. Bhatawadekar S, Chen Y, Ohishi J, Hernandez P, Brown T, Mcparland C, Maksym G. A study of artifacts and their removal during forced oscillation. Annual Meeting, Biomedical Engineering Society. Chen, Y, Brown T, Bhatawadekar S, Leary D, Peters U, Maksym G. A method for assessing glottis aperture variation on airway resistance by forced oscillation. Annual Meeting, Biomedical Engineering Society. Dalhousie University | 23 McNeil M, Brown T. Laryngology practice in Canada: Current trends and future directions. 64th Annual Meeting, Canadian Society of OtolaryngologyHead & Neck Surgery. Jaggi R, Massoud E, Bullock M, Brown T: A rare case of laryngeal Crohn’s disease with airway obstructive symptoms: Presentation and management. 64th Annual Meeting, Canadian Society of OtolaryngologyHead & Neck Surgery. Hilal A, Brown T, Taylor M. Accuracy of flexible versus rigid laryngoscopic photo-documentation. 64th Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Brownstone R. In search of lost motoneurons or “A la recherche du motoneuruone perdu.” Motoneuron Meeting. Brownstone R. Towards north-south integration: Possible contributions of dorsal interneurons to motoneuron output during locomotion. Department of Neuroscience, Karolinska Institute. Brownstone R. It makes sense: Characterization of spinal sensorimotor microcircuit involved in locomotion. Rexed Lecture, Uppsala, Stockholm. Christie S. Neuromonitoring as it applies to the direct lateral approach. MAST Course. Christie S. Interspinous process device concepts. MAST Course. Christie S. Minimally-invasive decompression and fixation for lumbar degenerative and traumatic spine. 8th Annual Caribbean Neurosciences Symposium. Christie S. Minimally-invasive decompression of lumbar spine. 8th Annual Caribbean Neurosciences Symposium. Christie S. Percutaneous instrumentation techniques in the lumbar spine. 8th Annual Caribbean Neurosciences Symposium. Christie S. A pilot project to study the effects of conservative treatment for low back pain. 11th Annual Scientific Conference, Canadian Spine Society. Christie S. Accelerometric gait analysis of cervical myelopathy. Annual Scientific Meeting, Canadian Spine Society. Clarke D. Rubber hose, nose and brain surgery. Dalhousie Department of Surgery Grand Rounds. Brownstone R. Probing spinal microcircuits involved in motor activity. Institute of Experimental Medicine. Clarke D. Surgical simulation. Annual Meeting, Oregon Neurosurgical Society. Brownstone R. Spinal locomotor networks: Identification of a cutaneous reflex microcircuit. Department of Physiology, University of Manitoba. Clarke D. Getting head-injured patients to neurosurgical care: How are we doing? Trauma 2010 Conference. Brownstone R. It makes sense: Characterization of a spinal sensorimotor microcircuit involved in locomotion. Department of Physiology, University of Copenhagen. Clarke D. Diagnosis and treatment in epilepsy: Epilepsy surgery. Capital District Health Authority Educational Course for Health Professionals. Casha S. Clinical predictors of recovery following blunt spinal cord trauma: A systematic review. Annual Meeting, Congress of Neurological Surgeons. Casha S. Benefit of minocycline in spinal cord injury: Results of a doubleblind randomized placebo-controlled pilot study. Clinically Isolated Syndrome & Multiple Sclerosis Trial Investigator Meeting. Casha S. Thoracolumbar fracture dislocation. Annual Meeting, American Association of Neurological Surgeons. Casha S. Evaluation of Fusion. Annual Meeting, American Association of Neurological Surgeons. Christie S. Spinal cord injury. MD Trauma Telehealth Education Session. Christie S. Spine controversies: Course-role of lumbar interbody fusion. Canadian Neuroscience Federation. Christie S. Spinal cord injury. Annual Meeting, Trauma Association of Canada. Christie S. Spinal injuries. Annual Meeting, Trauma Registry Information Specialists of Canada. Christie S. Current surgical techniques and approaches to minimallyinvasive spine surgery. 78th Annual Meeting, American Association of Neurological Surgeons. Christie S. Complications of cervical fusion. Canadian Motion Focus Group. Christie S. Best clinical scenario for cervical artificial disc replacement (ADR). Canadian Motion Focus Group. Christie S. Failure modes of cervical ADR. Canadian Motion Focus Group. Christie S. Osteoporotic compression fractures: Overview, radiographic considerations. Approaches and Techniques. MAST Course. Christie S. Clinical evidence regarding kyphoplasty. MAST Course. Clarke D. Qualitative and quantitative analysis of ski and snowboard helmet use in Nova Scotia. Recreation Nova Scotia Research Symposium. Clarke D. The effects of helmet use pre- and post-mandatory helmets for skating: The Halifax experience. Recreation Nova Scotia Research Symposium. Clarke D. White matter functional MRI in callosotomy patient. 16th Annual Meeting, Organization for Human Brain Mapping. Clarke D. Pre-hospital care pathways for major head injury. Annual Scientific Meeting, Trauma Association of Canada. Clarke D. Long-term functional outcomes following major traumatic brain injury. Annual Scientific Meeting, Trauma Association of Canada. Clarke D. NCAM is important for retinal ganglion cell function throughout aging. Canadian Association for Neuroscience. Clarke D. NCAM is important for retinal ganglion cell function throughout aging. 14th International Symposium on Retinal Degeneration. Clarke D. Head injury in Nova Scotia. Trauma Rounds, Dalhousie University. Clarke D. Virtual reality brain surgery: Training the next generation of neurosurgeons. Halifax Brain Tumour Information Day Conference. Clarke D. Helmet safety. Media: Breakfast Television, CTV Atlantic. Clarke D. Mandatory helmet regulation. Media: Live At 5, CTV Atlantic and CBC Radio Nova Scotia. Dunbar MJ. Femoral neck modularity in total hip arthroplasty: The missing link-opposes. Current Concepts in Joint Replacement. Dunbar MJ. Minimizing infection risk: Fortune favors the prepared mind. Current Concepts in Joint Replacement. Dunbar MJ. Hip and knee arthroplasty: What’s new, what’s true, does it matter? Current Concepts in Joint Replacement. 24 | Department of Surgery Dunbar MJ. Moderator, Orthopaedic crossfire: Controversies in knee arthroplasty. Current Concepts in Joint Replacement. Dunbar MJ. The introduction and evaluation of new technologies in surgery. Department of Surgery Grand Rounds, University of Saskatchewan. Dunbar MJ. Computer-assisted total knee arthroplasty: Where are we now and where are we going with this? Residents’ Research Day, University of Saskatchewan. Dunbar MJ. Alternate bearings in total hip arthroplasty. Residents’ Research Day, University of Saskatchewan. Dunbar MJ. Modern advances in hip and knee arthroplasty. Arthritis Society Public Forum. Dunbar MJ. Chair, Symposium II: Innovation in bearing surfaces. Atlantic Provinces Orthopaedic Society. Dunbar MJ. Alternate bearing surfaces. Atlantic Provinces Orthopaedic Society. Dunbar MJ. Keep people moving. Dalhousie Surgery Research Information Day. Dunbar MJ. Symposium moderator, Joint replacement registries: An international perspective. Canadian Orthopaedic Association. Dunbar MJ. Paper session moderator, COA/CORS combined knee arthroplasty. Canadian Orthopaedic Association. Dunbar MJ. Instructional course lectures moderator, Alternate bearings in total hip arthroplasty. Canadian Orthopaedic Association. Dunbar MJ. Patellar resurfacing in total knee arthroplasty (TKA). Total Knee Solutions: Complex Primary & Revision Knee. Dunbar MJ. Rethinking patella replacement: Is it really necessary? Current Concepts in Joint Replacement. Dunbar MJ. Femoral neck modularity in total hip arthroplasty: The missing link-opposes. Current Concepts in Joint Replacement. Dunbar MJ. Moderator, Revision knee arthroplasty: Doin’ the right thing. Current Concepts in Joint Replacement. Dunbar MJ. Case presentations: Revision TKA. Continuing Orthopaedic Education Meeting. Dunbar MJ. Moderator, Revision TKA techniques. Continuing Orthopaedic Education Meeting. Dunbar MJ. Bearing surfaces in modern TKA. Continuing Orthopaedic Education Meeting. Dunbar MJ. Outcomes of primary TKA. Continuing Orthopaedic Education Meeting. Dunbar MJ. Choice of implants in revision TKA. Continuing Orthopaedic Education Meeting. Dunbar MJ. Revision TKA for periprosthetic fractures. Continuing Orthopaedic Education Meeting. Dunbar MJ. Form follows function in TKA: An update on new advances in total knee surgery. Rheumatology Rounds. Dunbar MJ. Fractures of the femoral neck: Management and outcomes. Geriatric Academic Rounds, Dalhousie University. Wilson DAJ, Hubley-Kozey C, Dunbar MJ, Astephen Wilson JL. Preoperative muscle-activation patterns affect implant migration. Canadian Orthopaedic Association. Dunbar MJ. Trends and updates in total knee arthroplasty: Navigation and TKA. Canadian Orthopaedic Association. Bohm E, Dunbar MJ, Frood J, Johnson T, Morris K. Re-hospitalizations, early revisions, infections and costs following joint replacement surgery. Annual Meeting, American Academy of Orthopaedic Surgeons. Dunbar MJ. Techniques in revision total knee arthroplasty. Annual Meeting, American Academy Of Orthopaedic Surgeons. El-Hawary R, Sturm, Patrick PF, Cahill J, Samdani AF, Vitale MG, Gabos P, Bodin N, d’Amato R. Sagittal spinopelvic parameters of children with early-onset scoliosis. 4th International Congress of Early Onset Scoliosis. El-Hawary R, Maclellan B, Cook C, Leahey L, Hyndman JC. Extension type II supracondylar humerus fractures: A radiographic outcomes study of closed reduction and cast immobilization. 65th Annual Meeting, Canadian Orthopaedic Association. El-Hawary R, Francis A, MacNeil J. Systematic review of rigid, locked, intramedullary nail insertion sites and avascular necrosis of the femoral head in the skeletally immature. 65th Annual Meeting, Canadian Orthopaedic Association. El-Hawary R, Sturm P, Cahill P, Samdani A, Vitale M, Gabos P, Bodin N, d’Amato C. Sagittal spinopelvic parameters of children with early-onset scoliosis. 45th Annual Meeting, Scoliosis Research Society. El-Hawary R, Sturm R, Cahill P, Samdani A, Vitale M, Gabos P, Bodin, d’Amato C. Sagittal spinopelvic parameters of children with early-onset scoliosis. 17th International Meeting on Advanced Spine Techniques. El-Hawary R, Howard J, Cowan K, Sturm P, d’Amato C. Variability in the measurement of sagittal spinopelvic parameters in children with earlyonset scoliosis. 17th International Meeting on Advanced Spine Techniques. Douglas H, Goytan M, Lewis S, Jarvis J, Carey T, Gurr K, Labelle H, Parent S, Abraham E, Manson N, El-Hawary R, Howard J. The barriers to performing spinal surgery for deformity in Canada: A crosscountry perspective. 60th Annual Meeting, Canadian Spine Society. El-Hawary R, Francis A, Lee J, Lane R. Pressure distribution of intraoperative chest pad designs in patients with adolescent idiopathic scoliosis. 65th Annual Meeting, Canadian Orthopaedic Association. El-Hawary R, Francis A, Lee J. Bead placement protocol for follow-up of thoracic spinal fusion using roentgen stereophotogrammetric analysis (RSA). 65th Annual Meeting, Canadian Orthopaedic Association. El-Hawary R, Camus T, Maclellan B, Cook C, Leahey L, Hyndman J. Extension type II supracondylar humerus fractures: A radiographic outcomes study of closed reduction and cast immobilization. Annual Meeting, Pediatric Orthopaedic Society of North America. El-Hawary R, Francis A, Lee M. Bead placement protocol for follow-up of thoracic spinal fusion using roentgen stereophotogrammetric analysis (RSA). Upstate New York Biomedical Engineering Career Conference. Wiebe S, Klassen D, Bonjer J, Lawlor D, Plowman J, Ransom T, Vallis M, Ellsmere J. Starting a laparoscopic sleeve gastrectomy program: Short-term outcomes. Society of American Gastrointestinal Endoscopic Surgeons. Wiebe S, Klassen D, Bonjer J, Lawlor D, Plowman J, Ransom T, Vallis M, Ellsmere J. Laparoscopic sleeve gastrectomy in type II diabetic patients: Promising early results. Society of American Gastrointestinal Endoscopic Surgeons. Ellsmere J, Stoll J, San José Estépar R, Vosburgh K. Tracking laparoscopic ultrasound probe improves surgeon performance: Early clinical experience. Society of American Gastrointestinal Endoscopic Surgeons. Berzin T, Majumder S, Mahadevan A, Pawa R, Ellsmere J, Sepe P, La Rosa S, Pleskow D, Chuttani R, Sawhney M. Comparison of EUS vs. surgery for placement of fiducials in patients with pancreatic cancer. American Society of Gastrointestinal Endoscopy. Dalhousie University | 25 Alawashez A, Ellsmere J. Interventional radiology-assisted endoscopic transgastric peripancreatic fluid collection drainage. Society for Surgery of the Alimentary Tract. Fleetwood I. Asymptomatic aneurysms and arteriovenous malformations. 10th Stroke Review Course for Neurology Residents. Fleetwood I. Emergency room diagnosis and subarachnoid hemorrhage. 10th Stroke Review Course for Neurology Residents. Fleetwood I. Management of other stroke subtypes: Intracerebral hemorrhage malignant MCA infarction, carotid dissection, cerebellar stroke. 45th Annual Congress, Canadian Neurological Sciences Federation. Fleetwood I. Surgical management of arteriovenous malformation. 45th Annual Congress, Canadian Neurological Sciences Federation. Fleetwood I. Clinical trials update: Carotid endarterectomy vs. stenting. 6th Atlantic Canada Stroke Conference. Fleetwood I. Update on Canadian best practice guidelines for stroke. Dalhousie Clinical Neuroscience Grand Rounds. Glazebrook M, Boyd G, Lalond K, Daniels T, Copithorne P. Openingwedge versus proximal chevron osteotomy for hallux valgus with increased intermetatarsal angle. 26th Annual Summer Meeting, American Orthopaedic Foot & Ankle Society. Copithorne P, Boyd G, Lalond K, Daniels T, Glazebrook M. Openingwedge versus proximal chevron osteotomy for hallux valgus with increased intermetatarsal angle. American Academy of Orthopaedic Surgeons. Glazebrook, M. Evidence-based medicine: What is it and how should it be used? 26th Annual Summer Meeting Evidence-Based Medicine Symposium, American Orthopaedic Foot & Ankle Society. Glazebrook, M. Developing a scoring system for the clinical use of Augment® (biomimetic) bone graft substitute in hind foot arthrodesis. 26th Annual Summer Meeting Precourse: Satellite Symposium, American Orthopaedic Foot & Ankle Society. Glazebrook, M. Operative treatment of end-stage ankle arthritis: Fusion vs. replacement…which is best? Visiting Professor, Annual Meeting, Canadian Physical Therapy Orthopaedic Division. Glazebrook, M. Combined paper session: Arthroplasty knee. Canadian Orthopaedics Association and Canadian Orthopaedic Research Association. Glazebrook, M. Evidence-based medicine for treatment of tendon pathology: Achilles. Annual Meeting, Canadian Orthopaedics Association. Glazebrook, M. Evidence-based treatment of Achilles tendon ruptures. Annual Meeting, Canadian Orthopaedics Association. Glazebrook, M. Update on ankle arthritis clinical care and research. Visiting Professor, Division of Orthopaedic Surgery, Campbell Clinic—Grand Rounds Presentation. Glazebrook M. The diagnosis and treatment of acute Achilles tendon ruptures: Guideline and evidence report. American Academy of Orthopaedic Surgeons: AAOS Guidelines and Media Briefing. Gross M, Amirault D, Hennigar A, Dunbar MJ. One-year results of an RCT using RSA to compare minimally-invasive surgery to standard exposure in primary uncemented modular total hip arthroplasty. Canadian Orthopaedic Association. Gross M, Amirault D, Dunbar MJ. Femoral neck fractures with a modular THR System. Canadian Orthopaedic Association. Hancock Friesen C, O’Blenes S. Morbidity in pediatric cardiac surgery: A standardized approach for classification and weighting. Congenital Heart Surgeons’ Society. Hancock Friesen C, O’Blenes S. Continuous quality improvement in cardiac surgery: Morbidity workshop. Canadian Cardiovascular Congress. Hancock Friesen C. Mitral valve surgery: Options and challenges. Pediatric Cardiology Symposium: Canadian Cardiovascular Congress. Spencer R, Bower J, Yates G, Miller J, Kirk S, Hancock Friesen C. The role of peer mentors in enhancing school-based physical activity: Phase I. Canadian Cardiovascular Congress. Hancock Friesen C. Improving pediatric cardiac surgical morbidity capture and classification. Canadian Cardiovascular Congress. Shanmugam G, Hancock Friesen C. Exploring our horizons: Changes, challenges and future directions of health research. Interdisciplinary Research Conference. Spencer B, Bower J, Miller J, Yates G, Mullenger R, Kirk S, Hancock Friesen C. Advancing population health intervention research to promote health equity. Canadian Institutes of Health Research Population Health Symposium. Burton H, Morrison S, Mahon K, Soder C, O’Blenes S, Hancock Friesen C. Extracorporeal membrane oxygenation in a low-volume program: The role of RRTs and RNs. 21st Annual Conference, Extracorporeal Life Support Organization. Shanmugam G, Clark L, Burton H, Warren A, O’Blenes S, Hancock Friesen C. The new horizon for improving patient outcomes: Morbidity. Pediatric Cardiac Surgery, IWK. King C, Devitt J, Lee T, Hancock Friesen C. Neutrophil-mediated smooth muscle loss precedes allograft vasculopathy. American Transplantation Congress. Devitt J, King C, Lee T, Hancock Friesen C. Prolonged cold ischemia exacerbates cardiac allograft vasculopathy through an enhanced innate immune response. American Transplantation Congress. Spencer R, Xei W, Hoyt J, Yates G, Miller J, Hancock Friesen C. Results of an intensive physical activity intervention in an urban elementary school. Integrated Health Research Training Program Research Day. Abonowara A, Quraishi A, Sapp J, Hart RD, Alaqambar M, Saric A, Rajaraman M, Imran A. Patients with thyroid cancer on TSH suppression have a high risk of atrial fibrillation. Endo 2010: The 92nd Annual Meeting. Hart RD. Technology in thyroid surgery. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Macdonald K, Hart RD, Taylor SM, Mendez A. Eyelid and brow asymmetry in patients evaluated for blepharoplasty. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Al-Gilani M, Taylor SM, Williams B, Trites J, Bullock M, Hart RD. A case of sarcomatoid carcinoma of the maxilla. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Belyea J, Taylor SM, Rigby M, Trites J, Hart RD. Wait times for head and neck cancer patients in the Maritime provinces. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Annamalai S, Taylor SM, Trites J, Hart RD. A Canadian-based survey on pre and postoperative microvascular free flap management. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Amoodi H, Hart RD. Causes of otolaryngology same-day surgery cancellation at two Canadian centres. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Macdonald K, Taylor SM, Trites J, Dunbar M, Henigar A, Hart RD. The effect of fibula and anterolateral thigh free flaps on the gait of head and neck cancer patients. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. 26 | Department of Surgery Williams B, Al-Gilani M, Taylor SM, Trites J, Bullock M, Hart RD. Intraoperative factors associated with adverse outcomes in head and neck cancer patients. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Shahnavaz A, Taylor SM, Trites J, Nasser J, Bullock M, Hart RD. Molecular biology of well-differentiated thyroid cancers. Annual Otolaryngology Research Day, Dalhousie University. Fung E, Taylor M, Bullock M, Rajaraman M, Trites J, Hart RD. The role of PET-CT scans in directing neck dissections in oropharyngeal squamous cell carcinoma following primary radiation. Annual Otolaryngology Research Day, Dalhousie University. Williams B, Taylor SM, Gilani M, Trites J, Hart RD. Factors affecting morbidity and mortality in free flap patients. Annual Otolaryngology Research Day, Dalhousie University. Smith M, Giacomantonio C, Hoskin D. Fisetin-induced apoptosis in breast cancer cell lines involves cell-cycle arrest and mitochondrial destabilization. Beatrice Hunter Cancer Research Institute Cancer Research Symposium. Conrad C, Hilchie A, Hoskin D, Liwski R. Human hepcidin is cytotoxic to multiple myeloma cells. Beatrice Hunter Cancer Research Institute Cancer Research Symposium. Conrad C, Doucette C, Hilchie A, Hoskin D, Liwski R. Pleurocidinderived cationic antimicrobial peptides are cytotoxic to multiple myeloma cells in vitro and in vivo. Beatrice Hunter Cancer Research Institute Cancer Research Symposium. Greenshields A, Hoskin D. The anti-malarial compound artesunate induces reactive oxygen species-dependent anti-breast cancer activity. Beatrice Hunter Cancer Research Institute Cancer Research Symposium. Cavanagh J, Taylor SM, Bullock M, Trites J, Hart RD. Hypercalcemia after level VI neck dissections completed for papillary thyroid cancer. Annual Otolaryngology Research Day, Dalhousie University. Hilchie A, Doucette C, Patrzykat A, Douglas S, Hoskin D. The cationic antimicrobial peptides NRC-03 and NRC-07 cause cytolysis in breast cancer cells and exhibit anti-tumour activity in vivo. Beatrice Hunter Cancer Research Institute Cancer Research Symposium. Gilani M, Taylor M, Brake M, Trites J, Hart RD. Reconstruction using free flaps in total laryngectomy patients: Does it decrease the incidence of pharyngocutaneous fistulae? Annual Otolaryngology Research Day, Dalhousie University. Setog, Moore J, Hoskin D, Wang J. IL-17A and IL-17F inhibit breast cancer cell growth in vitro. Beatrice Hunter Cancer Research Institute Cancer Research Symposium. Grandy M, Taylor M, Trites J, Bullock M, Hart RD. Parotid masses and malignancy at the QEII: A 20-year perspective. Annual Otolaryngology Research Day, Dalhousie University. Shahanavaz A, Trites J, Taylor M, Bullock M, Pinto D, Karakach T, Douglas S, Singh R, Hart RD. Quantitative analysis of serum markers for welldifferentiated thyroid cancer. Annual Meeting, American Head & Neck Society. Abonowara A, Quraishi A, Sapp J, Hart RD, Alaqambar M, Saric A, Rajaraman M, Imran A. Prevalence of atrial fibrillation in patients taking thyroid/TSH suppression therapy for the management of thyroid cancer. Research Day, Dalhousie University Department of Medicine. Jordan J, Zaki A, Ross B, Hirsch G, Lee TD. Contribution of pre-existing vascular disease to allograft vasculopathy in a murine model. International Society for Heart & Lung Transplantation. Maher A, Helyer L, Coburn N. A systematic review of the benefits of palliative or non-curative surgery in gastric cancer management. International Congress on Palliative Care. Helyer L. Gastric cancer; advances in treatment. Dalhousie General Surgery Refresher Course. Helyer L. Prevention of the contra-lateral breast cancer; what is the risk and what can we do? Cape Breton Cancer Update. Helyer L. Peri-operataive breast cancer considerations. ACOG Charlottetown. Hirsch G. The etiology of allograft vasculopathy. International Society for Heart & Lung Transplantation. Hirsch G. The role of CD8+ T cells in the development of allograft vasculopathy. Dalhousie Department of Surgery Research Day. Hirsch G. The etiology of allograft vasculopathy. Dalhousie Department of Pathology Research Day. Hirsch G. The etiology of allograft vasculopathy. Dalhousie Department of Medicine Research Day. Yaffe P, Walsh M, Hoskin D. The dietary phytochemical piperine inhibits HT-29 human colon cancer cell growth. Annual Meeting, American Society of Colon and Rectal Surgeons. Smith M, Giacomantonio C, Hoskin D. Exploring the flavonoid fisetin as a novel treatment for breast cancer. Canadian Surgery Forum. Johnson M. Update on the Terry Fox Research Institute. Atlantic Cancer Research Institute. Johnson, M. Mesothelioma: Can we cure the incurable? Flanders Visiting Lectureship in Lung Oncology, McGill University. Johnson, M. National lung screening study. Terry Fox Research Institute Atlantic Node Research Symposium. Johnson M. Terry Fox Research Institute Atlantic Node. Beatrice Hunter Cancer Research Institute. Richardson DP, Porter GA, Johnson P. Self-reported patterns of rectal cancer care among general surgeons in Canada. Canadian Surgery Forum, Canadian Association of General Surgeons. Richardson DP, Porter GA, Johnson P. A population-based description of the presentation and management of recurrent rectal cancer. Canadian Surgery Forum, Canadian Association of General Surgeons. Altaf A, Ellsmere J, Bonjer J, Klassen D. Hand-assisted laparoscopic splenectomy compared to conventional laparoscopic splenectomy. Society of American Gastrointestinal Endoscopic Surgeons. Sopel M, Lee T, Légaré JF. Fibrocytes, a novel cellular mediator, infiltrate the myocardium prior to the development of myocardial fibrosis. Canadian Cardiology Society. Kelly R, Buth K, Heimrath O, Basta M, Légaré JF. Under-utilization of implantable cardioverter-defibrillators after coronary artery bypass grafting in patients with impaired left ventricular function. American Heart Association. Rosin N, Sopel M, Lee T, Légaré JF. The role of connective tissue growth factor in fibrosis after angiotensin II exposure. Canadian Cardiology Society. Kelly R, Buth K, Légaré JF. Completeness of revascularization predicts long-term survival benefit in CABG surgery. Canadian Cardiology Society. Kelly R, Buth K, Légaré JF. BIMA grafting as compared to multiple arterial grafts without BIMA confers improved long-term survival after CABG. Canadian Cardiology Society. Rosin N, Sopel M, Oxner A, Ma I, Falkenham A, Darosa M, Lee T, Légaré JF. Mesenchymal progenitor cells play a role in the development of cardiac fibrosis secondary to angiotensin II exposure. Young Investigator Forum. Sopel M, Lee T, Légaré JF. The role of activated protein C (APC) in myocardial fibrosis. Young Investigator Forum. Dalhousie University | 27 LeGay D. Rehabilitation of the post-op rotator cuff repair concepts. Nova Scotia Orthopaedic Physiotherapy Association. Mendez I. Survival and function of grafter cells in Parkinson’s disease and Huntington’s disease animal models in the clinic. NeuroStemcell Workshop. LeGay D. The evidence for hip arthroscopy: Grading the current indications. Clearwater Innovative Arthroscopy Meeting 2010. Mendez I. Brain repair and robotics: Medicine of the future. Government House Public Lecture Series. Fieldhouse E, Campbell-Yeo M, Yanchar NL, Lopushinsky S. A clinical practice update on the Nova Scotia experience with sutureless nonoperative closure of gastroschisis performed in the NICU. Neonatal Advanced Nursing Practice Forum. Mendez I. Robotics in medicine: Explore innovation and technology for medical work in remote and isolated communities. Department of Health and Community Services. McNeely D. Surgical management of sagittal carniosynostosis. Craniosynostosis Symposium. Molinari M. Familial pancreatic cancer registry: A framework for clinical epidemiological and genetic studies. Queen Elizabeth II Foundation Presentation. McNeely D. Tethered cord syndrome: Pediatric and adult considerations. Atlantic Spine Meeting. Molinari M. Biliary leaks after laparoscopic cholecystectomy. Nova Scotia General Surgery Refresher Course. McNeely D. Pediatric neurotrauma. Pediatric Intensive Care Unit Nursing Education Day, IWK. Molinari M. Limitation of liver resection for primary and secondary liver tumours: GIANT Meeting. McNeely D. Transition of care to an adult spina bifida clinic: Patient perspectives and medical outcomes. National Conference, American Academy of Pediatrics. Molinari M. Evidence-based approach to hepatocellular carcinoma: Resection, ablation, liver transplantation. Live-Right Public Forum Session. McNeely D. Distraction osteogenesis for expansion cranioplasty in symptomatic craniostenosis. AANS/CNS Pediatric Section Meeting. Molinari M. Surgical management of colorectal liver metastases. Surgical Oncology Education Day, Dalhousie University. Mendez I. Art and science: Two sides of the human brain. Academia Nacional De Bellas Artes. Molinari M. Evidence-based evaluation of ablation therapy for primary and secondary hepatic tumours. Gastrointestinal Medicine Rounds, Dalhousie University. Mendez I. Neurosurgery of the 21st century: Brain repair and robotics. Medtronic Headquarters. Mendez I. Neurosurgical techniques for cell transplantation into the human brain. National Institute of Health – Sham Neurosurgical Procedures in Clinical Trials. Mendez I. The Halifax Injector: A computer system for cell transplantation. Transeuro Research Consortium Meeting. Mendez I. Clinical neural transplantation for Parkinson’s disease: Methodological considerations. International Conference of Stem Cells and Regenerative Medicine. Mendez I. Neurosurgery of the future: Robotics and brain repair. Visiting Professor, Havana, Cuba. Mendez I. Science, art and humanities: A neurosurgeon’s journey. The Kris Kumar Lecture. Mendez I. Neurosurgery of the future: Brain repair and robotics. Canadian Orthopaedic Nurses Association. Mendez I. Beautiful Minds series with Dr. Norman Cornett. Guest Speaker, Montreal. Mendez I. Brain injury and repair. Neuroscience in the Courtroom Conference. Mendez I. New advances in brain repair. Department of Ophthalmology, Dalhousie University. Mendez I. Narrowing the gap of inequality: A physician’s personal responsibility. Global Health Lecture Series, Dalhousie International Health Office. Mendez I. Activa rechargeable battery. CBC Radio. Mendez I. Activa rechargeable battery. CBC Television. Mendez I. School laptop program in Nain, Labrador. CBC Radio. Mendez I. Brain repair in Parkinson’s disease: The clinical challenge. Activated Egg Symposium. Molinari M. The predictive mortality of MELD And MELDNA is underestimated for patients living in rural areas. International Hepatobiliary and Pancreatic Association Meeting. Molinari M. Evidence-based medicine for ablation of hepatic masses. International Hepatobiliary and Pancreatic Association. Alhawsawi A, Molinari M, Aljiffry M, Walsh M, Alwayn I, Peltekian K. Meta-analysis of ischemic pre-conditioning in liver transplantation. International Hepatobiliary and Pancreatic Association. Hilal A, Van Wijhe R, Morris DP. Joint knives in stapes surgery: Are they fit for purpose? 64th Annual Meeting, Canadian Society of Otolaryngology. Morris, DP. Cholesteatoma: The science. Meeting of the Section of Otology, Royal Society of Medicine. Morris DP. BAHA and unilateral sensorineural hearing loss. BAHA UK Professionals Group Annual Meeting. Yohn DC, Van Wijhe R, Morris DP. Transcranial transmission with the BAHA after graded temporal bone resections. 64th Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Desrosiers M, Kelty, S, Morris DP. Biofilms and the ear. 64th Annual Meeting, Canadian Society of Otolaryngology. Bezuhly M, Cullen R, Esmon C, Morris SF, West K, Johnston B, Liwski R. Activated protein C and over-expression of its receptor inhibit tumour metastasis. Plastic Surgery Research Council Annual Meeting. Chung B, Morris SF. Validation of the Michigan hand questionnaire in Canadian Maritime population. Plastic Surgery Research Council Annual Meeting. Almutairi K, Tang M, Morris SF. Three-dimensional anatomical study of the vascular supply to the tensor fascialata and overlying skin. Annual Meeting, Canadian Society of Plastic Surgeons. Bezuhly M, Cullen R, Esmon C, Morris SF, West KA, Johnston B, Liwski R. Role of activated protein C and its receptor in inhibition of melanoma metastasis. Canadian Society of Plastic Surgeons Annual Meeting. 28 | Department of Surgery Chung B, Morris SF. Factors affecting privatization for consultation regarding carpal tunnel syndrome. Annual Meeting, Canadian Society of Plastic Surgeons. Daigle R, Urquhart R, Cox M, Grunfeld E, Porter GA. A populationbased study of emergency room presentation in colorectal cancer. Canadian Surgical Forum. Appleton S, Ngan A, Kent B. Morris SF. Risk factors influencing transfusion rates in DIEP flap breast reconstruction. Annual Meeting, Canadian Society of Plastic Surgeons. Urquhart R, Bu J, Porter GA, Dewar R, Moineddin R, Grunfeld E. Relationship between survival and lymph node assessment from a populationbased study of colorectal cancer patients. Annual Meeting, American Society of Clinical Oncology. Morris SF. Basic anatomical knowledge of skin perforators. 13th International Course Perforator Flaps. Prasad V, Almutairi K, Kinble F, Stewart F, Morris SF. Dorsolateral musculocutaneous perforators of the posterior intercostal artery— anatomical study. 13th International Course Perforator Flaps. Morris SF. Disasters of the masters. 13th International Course Perforator Flaps. Morris SF. Live surgery ALT flap to lower leg defect. 13th International Course Perforator Flaps. Bezuhly M, Cullen R, Esmon C, Morris SF, West K, Johnston B, Liwski R. Activated protein C and over-expression of its receptor inhibit tumour metastasis. Plastic Surgery Research Council. Chung B, Morris SF. Validation of the Michigan hand questionnaire in a Canadian Maritime population. Plastic Surgery Research Council. Morris SF. Vascular anatomy of the integument and its importance to reconstructive surgery. Department of Anatomy & Neurobiology, Dalhousie University. Morris SF. Research update in plastic surgery. Dalhousie University Research Information Day. Morris, SF. Panelist, Perforator flaps. QMP Reconstructive Surgery Symposium. Morris, SF. Panelist, moderator, upper extremity reconstruction. QMP Reconstructive Surgery Symposium. Morris, SF. Panelist, moderator, lower extremity reconstruction. QMP Reconstructive Surgery Symposium. Ali A, Hancock Friesen C, Howlett S, O’Blenes S. The sodium-calcium exchange inhibitor SEA0400 prevents myocardial injury and enhances myofilament sensitivity to Ca2+ when used as a cardioplegia additive. American Heart Association. Ali A, Hancock Friesen C, Howlett S, O’Blenes S. Impact of the sodium/calcium exhchage inhibitor SEA0400 on intracellular calcium and contraction amplitude in an isolated cardiomyocyte model of cardioplegic arrest and reperfusion. Canadian Cardiovascular Congress. Porter GA, Urquhart R, Bu J, Johnson P, Grunfeld E. The impact of audit and feedback on nodal harvest in colorectal cancer (CRC). Annual Meeting, American Society of Clinical Oncology. Porter GA, Urquhart R, Bu J, McConnell Y, Grunfeld E. Timely access and quality of care in colorectal cancer: A population-based analysis. Annual Meeting, Society of Surgical Oncology. Urquhart R, Bu J, Porter GA, Dewar R, Moineddin R, Grunfeld E. Relationship between survival and lymph node assessment from a population-based study of colorectal cancer patients. Annual Meeting, Canadian Digestive Diseases. Donahoe L, Druhan K, Inglis K, Porter GA. Patient satisfaction with timeliness of care in surgically treated gastric cancer. Annual Meeting, Society of Surgical Oncology. Porter GA, Urquhart R, Bu J, McConnell Y, Grunfeld E. Timely access and quality of care in colorectal cancer: A population-based analysis GI cancer symposium. American Society of Clinical Oncology. Porter GA. Quality in cancer surgery: What is it and how do we measure it? HTG Williams Visiting Professor, University of Alberta Department of Surgery. Porter GA. How does science get into clinical cancer care? An open dialogue. Launch, Terry Fox Research Institute Atlantic Node. Porter GA. Colorectal liver metastases. Symposium for Surgical Treatment of Metastatic Disease, Cancer Care Nova Scotia Surgical Oncology Symposium. Stanish WD. Osteoarthritis of the knee. The Community Hospital Program, Faculty of Medicine, Dalhousie University. Stanish WD. An Olympic experience. Gaspers Senior Group. Stanish WD. Cartilage and bone transplantation. Academic Rounds, Dalhousie University. Stanish WD. University sports: Their importance. Annual Fundraising Dinner, University of Prince Edward Island Hockey. O’Blenes S. Continuous quality improvement in cardiac surgery. Canadian Cardiovascular Conference. Harris AA, Smith TD, Stanish WD, Sun J, Marchand C, Carli A, Henderson, J, Hoemann CD. Optimization of pre-solidified hybrid implants for subchondral bone reconstruction. Dal Surgery Research Day. Maddison A, Asada Y, Burge F, Johnston G, Urquhart R, Porter GA. Inequity in access to cancer care: A review of the Canadian literature. Canadian Association for Health Services and Policy Research Conference. Rutherford D, Hubley-Kozey C, Stanish WD. Knee-joint effusion affects periarticular muscle function during gait in moderate knee osteoarthritis. Dal Surgery Research Day. Urquhart R, Porter GA, Sargeant J, Grunfeld E. Exploring factors that influence the use of an innovation—synoptic reporting—in cancer care. Canadian Association for Health Services and Policy Research Conference. Restrepo A, Stanish WD, Hoemann CD, Buschmann MD, Shive M. Challenges in designing randomized clinical trials for cartilage repair: The BST-CarGel experience. National Orthopaedic Educational Society Meeting. Urquhart R, Bu J, Porter GA, Dewar R, Moineddin R, Grunfeld E. Relationship between survival and lymph node assessment from a population-based study of colorectal cancer patients. Canadian Digestive Diseases Annual Meeting. Stanish WD. The evolution of orthopaedic nursing: One surgeon’s perspective. 33rd Annual Conference, Canadian Orthopaedic Nurses Association. Gordon ML, Cornacchi S, Farrokhyar F, Hodgson N, Porter GA, Quan ML, Wright F, Lovrics. Practice patterns and perceptions of margin status for breast-conserving surgery: A national survey of Canadian general surgeons. Canadian Surgical Forum. Stanish WD. Glenohumeral instability and SLAP. Academic Rounds, Dalhousie University. Stanish WD. Labral repair. Rotator cuff repair. 2nd Annual Meeting, Atlantic Arthroscopy Society. Dalhousie University | 29 Stanish WD. Cartilage regeneration: Recent advances, and Shoulder: Hands-on Assessment. Cutting Edge Sport Medicine Symposium. Rutherford D, Landry S, Hubley-Kozey C, Stanish WD. Toe-out gait affects knee biomechanics and neuromuscular function in asymptomatic individuals and those with moderate knee osteoarthritis. 44th Annual Meeting, Canadian Orthopaedic Research Society. Stanish WD. Arthroscopic management of shoulder instability. Shoulder Arthroscopy Symposium. Stanish WD. Forty years of sport medicine. Dalhousie Medical School Reunion. Restrepo A, MacDonald P, Mohtadi N, Marks P, Malo M, McCormack R, Desnoyers J, Pelet, Stanish WD. Randomized multi-centre clinical trial comparing BST-CarGel to microfracture in repair of the femoral condyle: Interim results from 41 patients. 9th World Congress, International Cartilage Repair Society. Methot S, Hoemann CD, Rossomacha E, Restrepo A, Stanish WD, MacDonald P, Mohtadi N. ICRS histology scores of biopsies from an interim analysis of a randomized controlled clinical trial show significant improvement in tissue quality at 13 months for BST-CarGel versus microfracture. International Cartilage Repair Society. Changoor A, Nelea M, Tran-Khanh N, Methot S, Restrepo A, Stanish WD. BST-CarGel treatment shows trend of improved collagen architecture and stratified hyaline structure compared to microfracture in 13-month biopsies from an interim analysis of a randomized controlled clinical trial. International Cartilage Repair Society. Hoemann CD, Tran-Khanh N, Methot S, Chen G, Marchand C, LascauComan V, Rossomacha E, Jarry C, Restrepo A, Stanish WD. Correlation of tissue histomorphometry with ICRS histology scores in biopsies obtained from a randomized controlled clinical trial comparing BST-CarGel versus microfracture. International Cartilage Repair Society. Lafantaisie Favreau CH, Guzman-Morales J, Sun J, Harris A, Smith TD, Carli A, Henderson J, Stanish WD. Novel pre-solidified chitosan/ blood implant provides local bone-marrow stimulation-associated biological activity in skeletally aged rabbits after a three-week treatment. International Cartilage Repair Society. Hoemann CD, Sun J, Gosselin Y, Hurtig MB, Carli A, Chen H, Stanish WD. Effect of microfracture and Jamshidi needle biopsy on ex vivo symptomatic OA knee condyles. International Cartilage Repair Society. Stanish WD. CarGel: A prospective study. Symposium, Innovation in Cartilage Regeneration, 49th Annual Meeting, Atlantic Provinces Orthopaedic Society. Stanish WD. Implications for return to work: Case management and clinical decision making. Knowledge translation workshop, “Why people keep hurting their backs: Recurrent low back injury: New directions through multi-disciplinary research.” Workers Compensation Board of Nova Scotia. Macdonald K, Taylor SM, Fung EW, Trites J, Barnsley P, Dunbar M, Leahey L, Hart RD. Effect of fibula free flap harvest on the gait of head and neck cancer patients. Annual Otolaryngology Research Day, Dalhousie University. Belyea J, Hart RD, Trites J, Taylor SM. Post-cancer treatment: Whistle deformity of the lip reconstruction. Annual Meeting, American Academy of Otolaryngology-Head & Neck Surgery. Hilal M, Brown T, Taylor M. Accuracy of flexible versus rigid laryngoscopic photo-documentation. Annual Otolaryngology Research Day, Dalhousie University. Mendez A, Taylor SM, Hart RD, Trites J, Bullock M. Undifferentiated high-grade pleomorphic sarcoma of the face. Annual Meeting, American Academy of Otolaryngology-Head & Neck Surgery. Reynolds L, Taylor SM, Rigby M, Trites J, Hart RD, MacLean M. Outcomes of endoscopic CO2 laser surgery for recurrent head and neck cancer. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Mendez A, Taylor SM, Hart RD, Trites J. Malignant carotid body tumours. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Brake M, Taylor SM, Al-Gilani M, Hart RD, Trites J. Submental liposuction: A new treatment option for lymphedema in head and neck cancer patients. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Brake M, Hart RD, Jain L, Trites J, Taylor SM. Submental liposuction for post-treatment lymphedema in the head and neck cancer patient. Annual Otolaryngology Research Day, Dalhousie University. Jaggi R, Hart RD, Trites J, Taylor SM. Donor site morbidity following para-median forehead flap reconstruction. Annual Otolaryngology Research Day, Dalhousie University. Belyea J, Hart RD, Rigby M, Trites J, Taylor SM. Wait times for head and neck cancer patients in the Maritime provinces. Annual Otolaryngology Research Day, Dalhousie University. Hilal A, Hart RD, Brown T, Taylor SM. Accuracy of flexible versus rigid laryngoscopic photo-documentation in diagnosing confusing laryngeal pathology. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. McNeil M, Bullock M, Hart RD Trites J, Taylor SM. The impact of multi-focal pattern of invasion on patient outcomes in oral squamous cell carcinoma. Annual Meeting, Canadian Society of Otolaryngology-Head & Neck Surgery. Bartlett C, Hart RD, Trites J, Taylor SM. Incidence of pulmonary complications in head and neck surgery patients. Annual Otolaryngology Research Day, Dalhousie University. Makki F, Hart RD, Rajaraman M, Trites J, Brown T, Taylor SM. Current practice patterns in the management of glottic cancer in Canada: Results of a national survey. Annual Otolaryngology Research Day, Dalhousie University. Restrepo A, MacDonald P, Mohtadi N Stanish WD. BST-CarGel and microfracture in repair of focal articular cartilage lesions on the femoral condyle. Clearwater Innovative Arthroscopy Meeting. McNeil Ml, Hart RD, Bullock M, Trites J, Taylor SM. The impact of multi-focal pattern of invasion on patient outcomes in oral squamous cell carcinoma. Annual Otolaryngology Research Day, Dalhousie University. Baker N, Buth K, Sullivan J. The relationship between left ventricular end-diastolic dimension and patient outcomes in isolated aortic valve replacement surgery: A retrospective study of cardiac cases in Nova Scotia. Canadian Cardiovascular Congress. Rigby M, Orlic J, Hong P, Broen T, Trites J, Hart RD, Taylor SM. Stroboscopy in the staging of laryngeal carcinomas. Annual Meeting, American Head & Neck Society. Sullivan J. Percutaneous valve implantation. Atlantic Canada Cardiovascular Symposium. T Rigby M, Hart RD, Reynolds L, Bullock M, Trites J, Taylor SM. Glottic carcinoma: Analysis of recurrences. Annual Otolaryngology Research Day, Dalhousie University. Rajaraman S, Taylor SM, Hart RD, Trites J, Bullock M, Hollenhorst H, Wilke D, Rajaraman M. PET scanning in head and neck cancer. 2010 Beatrice Hunter Cancer Research Institute Cancer Research Symposium. McNeil M, Bullock M, Hart RD, Trites J, Taylor SM. The impact of multi-focal pattern of invasion on patient outcomes in oral squamous cell carcinoma. Annual Meeting, American Head & Neck Society. 30 | Department of Surgery Arnason At, Hart RD, Nasser J, Trites J, Taylor SM, Bullock M. Diagnostic accuracy of fine needle aspiration biopsy of the parapharyngeal space. US & Canadian Academy of Pathology. Walling S. The effects of enforcement and education on helmet use in rural and urban Nova Scotia. Recreation NS Research Symposium. Walling S. The effects of enforcement and education on helmet use in rural and urban Nova Scotia. Annual Scientific Meeting, Trauma Association of Canada. Walling S. Long-term function outcomes after major traumatic brain injury. Annual Scientific Meeting, Trauma Association of Canada. Bance M. New bone-conduction technologies. Atlantic Innovation Fund (AIF), with team of six co-investigators. $3.1 million. 2006-2011. Bance M. XIAP transfection protection against age-related hearing loss. CIHR. $587,000. 2008-2013. Bance M, Dunbar M, Kozey C, Ellsmere J. Biomedical devices innovation. NSERC CREATE grant. $2.1 million. 2009-2014. Bance M. Tactile transducers in unilateral hearing loss. NSHRF. $150,000. 2008-2011. Bance M. Brain imaging of hearing deficit. NSHRF. $150,000. 2007-2010. Oliveira C, Pastor AC, Nasr A, Himidan S, Manson D, Yanchar NL, Brisseau G, Kim PCW. Discriminating preoperative features of pleuroplumonary blastomas (PPB) from congenital cystic adenomatoid malformations (CCAM): A retrospective age-matched study. American Pediatric Surgery Association Meeting. Bance M. Binaural integration and asymmetric hearing loss. Hearing Foundation of Canada. $25,000. 2009-2010. Parker JA, Chambers CT, Kalousek KS, Mcgrath PJ, Yanchar NL, Moore C, Von Baeyer CL. Are you okay? Parents’ responses to their children’s everyday pains. 8th International Symposium on Pediatric Pain. Bance M. Program support competition: Otology research program. Department of Surgery Research Fund, Dalhousie University. $150,000. 2009-2012. Yanchar NL. Management of major pediatric trauma cases. Pediatric Emergency Care Conference. Bance M. New tools for auditory imaging. Dalhousie Medical Research Foundation (DMRF). $10,000. 2009-2010. Yanchar NL. Acute abdominal pain and appendicitis in children. Dalhousie Videoconference CME Lecture Series. Bance M. Neural integration: Effect of stimulus level. CDHA. $15,000. 2009-2010. Currently Held Grants 2010 Alwayn I. Faculty of Medicine Clinical Scholar Award, Dalhousie University. $400,000. 2008-2013. Alwayn I. Optimizing steatotic livers for transplantation using a novel gene therapeutic approach. Canada Foundation for Innovation (CFI). $277,000. 2010-2011. Alwayn I, Légaré JF. Impact of obesity on transplantation. Nova Scotia Health Research Foundation (NSHRF). $10,000. 2010. Alwayn I. Optimizing steatotic livers for transplantation using a novel gene therapeutic approach. Capital District Health Authority (CDHA). $15,000. 2010. Brown J, Adamson R, Bance M. A high-resolution ultrasound endoscope for imaging the ear and auditory system. InNovacorp Early Stage Commercialization Fund. $33,000. 2010-2011. Brown J, Adamson R, Bance M. Beamformer for high-frequency ultrasound imaging of the auditory system. Natural Sciences and Engineering Research Council (NSERC). $150,000. 2010-2011. Adamson R, Bance M, Brown J, Wang J, Filliagi M. An implantable subcutaneous, piezoelectric hearing aid. NSHRF. $150,000. 2010-2013. Brown J, Bance M, Adamson R, Wang J. A high-resolution endoscopic ultrasound for the ear. Canadian Institutes of Health Research (CIHR). $118,600. 2010-2011. Brown J, Adamson R, Bance M. Technique for miniaturizing an ultrasonic endoscope for the auditory system. CDHA. $15,000. 2010. Adamson R, Brown J, Bance M. An optical coherence tomography system for high-resolution imaging of the middle ear. CDHA. $15,000. 2010. Bance M. Binaural integration: Effect of stimulus level. CDHA. $15,000. 2009-2010. Baskett R. Reducing post-operative major adverse cardiac events in cardiac surgery: Towards a prospective intervention. Heart and Stroke Foundation of Canada (HSFC). $42,025. 2010-2013. Baskett R. Reducing post-operative major adverse cardiac events in cardiac surgery: Towards a prospective intervention. CDHA. $14,060. 2010. Brownstone R. Control of movement: Regulation of spinal muscular circuits. CIHR. $833,775. 2010-2015. Brownstone R. Control of movement: Regulation of the pattern of locomotion. CIHR. $773,392. 2009-2014. Brownstone R. Control of movement: Brain stem control of locomotion. CIHR. $643,654. 2008-2013. Brownstone R. (PI). Brain Repair Centre: An integrative approach for functional restoration. CFI. $13,943,657. 2007-2010. Brownstone R. Control of movement: Regulation of motoneuron excitability. CIHR. $553,010. 2005-2010. Brownstone R, Fawcett J. Barbara Turnbull Award for highest-ranking spinal cord grant (tied in the rankings). CIHR. $50,000 (shared award). 2010. Casha S. Cerebrospinal fluid and MRI determinants of recovery from acute spinal cord injury in humans. Alberta Paraplegic Foundation. $200,000. 2010-2012. Casha S. Minocycline in acute spinal cord injury—a Canadian multicentre study. Alberta Paraplegic Foundation. $140,256. 2010-2012. Casha S. Post-traumatic NO-GAPDH-Siah 1-mediated apoptosis in the spinal cord. AO Spine North America. $31,558. 2009-2010. Casha S. A translational approach to neuro-inflammation and functional outcomes after human spinal cord injury. CIHR. $351,444. 2009-2012. Christie S. The legacy project. QEII Foundation. $5,000. 2010. Clarke DB. Influence of cell-adhesion molecules on neuron survival and plasticity in the adult central nervous system. NSERC. $132,500. 2006-2011. Dalhousie University | 31 Coles CP. Hip fracture evaluation with alternative of total hip arthroplasty versus hemi-arthroplasty (HEALTH): A multi-centre randomized trial comparing total hip arthroplasty and hemi-arthroplasty on re-operations and quality of life in patients with femoral neck fractures. CIHR. $140,721. 2008-2010. Glazebrook M. Feasibility trial to evaluate the safety and effectiveness of carticept MTP hemi-arthroplasty compared to MTP arthrodesis. Cartiva. $75,000. 2009-2010. Dunbar M. Preventing mobility and physical activity impairments: A longitudinal, multifactorial investigation of knee osteoarthritis progression. CIHR. $10,000. 2009-2010. Glazebrook M. A prospective, randomized, controlled, multicentre pivotal human clinical feasibility trial to evaluate the safety and effectiveness of Augment™ compared to autologous bone graft as a bone regeneration device in foot and ankle fusions. Biomimetic Therapeutics contracted research grant. $150,000. 2009-2010. Dunbar M. Conservative and surgical management of knee osteoarthritis based on an objective patho-mechanical framework. Department of Surgery Research Fund, Dalhousie University. $150,000. 2009-2012. Glazebrook M. A multi-centre, prospective, parallel group, randomized pilot study evaluating safety and preliminary effectiveness of Amplex compared to autograft bone in subjects undergoing foot and ankle fusion surgery. Bioset Therapeutics contracted research grant. $200,000. 2010. Dunbar M. Collaborative research and training experience program. NSERC. $2,000,000. 2009-2014. Hancock Friesen C. H2K: The role of peer mentors in enhancing school-based physical activity. NSHRF. $150,000. 2009-2012. Dunbar M. Co-investigator access to appropriate care across the continuum: Strategic management for timely treatment. CIHR. $2,500,000. 2008-2013. Hancock Friesen C. H2K: Expanding the program. Pfizer Canada Inc. $10,000. 2010. Dunbar M. Development of a clinical diagnostic system for assessing orthopaedic implant stability. AIF. $5,000,000. 2008-2013. Dunbar M. Extended prophylaxis in total hip replacements. CIHR. $2,900,000. 2006-2011. Dunbar M. Biomechanical and neuromuscular characteristics during gait in moderate knee osteoarthritis: A framework for developing and evaluating non-invasive interventions. NSHRF. $39,500. 2007-2010. Dunbar M. Biomechanical and neuromuscular characteristics during gait in moderate knee osteoarthritis: A framework for developing and evaluating non-invasive interventions. CIHR. $118,500. 2007-2010. Dunbar M. Psychosocial predictors of prolonged pain and disability following total knee arthroplasty. CIHR. $275,442. 2006-2011. El-Hawary R, Howard J. Pain at home in children following major surgery: Physical, psychological, and economic consequences. CIHR. $878,775. 2010 – 2015. El-Hawary R, Howard J. Validity of TcMEPs and SSEPs as early indicators of neural compromise in rat model of spinal cord compression. American Society of Neurophysiological Monitoring. $5,000. 2010. El-Hawary R, Howard J. Validity of TcMEPs and SSEPs as early indicators of neural compromise in rat model of spinal cord compression. IWK Health Centre. $4,000. 2010. Fawcett J. Maud Menten Finalist Award for highest-ranking CIHR grant for a new investigator. CIHR. $1,000. 2010. Fawcett J. Developing specific motoneuron subtypes from embryonic stem cells and induced pluripotent stem cells to treat neuromuscular disorders and paralysis due to injury. CIHR. $653,700. 2010-2015. Hancock Friesen C. H2K: Expanding the program. GlaxoSmithKline. $10,000. 2010. Hancock Friesen C. H2K: Anthropomorphic data endpoints. IWK. $4,000. 2010. Hancock Friesen C. Faculty of Medicine Clinical Scholar Award, Dalhousie University. $405,000. 2007-2012. Hancock Friesen C. Early innate events in allograft vasculopathy are exacerbated by ischemia reperfusion. CIHR. $102,375. 2009-2012. Hancock Friesen C. Follow-up of tetralogy of fallout patients: Transition from pediatric to adult care. IWK. $3,430/year, ongoing. Hancock Friesen C. Assembling a multi-disciplinary team to study the role of obesity in impaired solid organ transplant outcomes. NSHRF. $20,000. 2010. Hart R, Taylor SM, Trites J. Biomarkers for human health and wellness: Thyroid cancer. NSERC. $210,000. 2009-2010. Hoskin D. Thy-1: a T cell molecule with novel T cell receptor-like and costimulatory signaling properties. NSERC. $312,000. 2005-2010. Hoskin D. Molecular basis of selective killing of human breast cancer cells by the pleurocidin-like cationic antimicrobial peptides NRC-03 and NRC07. Canadian Breast Cancer Foundation (CBCF). $116,000. 2008-2010. Hoskin D. Treatment of intestinal inflammation with piperine, a dietary phytochemical with immune-modulating activity. CIHR. $239,781. 2008-2011. Hoskin D. Shared equipment for counting and sizing of cell populations. NSERC. $74,000. 2009-2010. Fawcett J. Elucidating the development of neural circuits involved in locomotion. CIHR. $804,170. 2010-2015. Hoskin D, Porter G, Johnston M. Cancer Research Training Program: A research legacy for Atlantic Canada. The Terry Fox Foundation Strategic Health Research Training Program in Cancer Research at CIHR. $1,950,000. 2009-2015. Fawcett J. YFP laser for spinning disk microscope. DMRF equipment grant. $30,000. 2010. Johnston M. (Halifax site PI) Pan-Canadian early lung cancer detection study. Terry Fox Research Institute. $6,500,000. 2008-2013. Fawcett J. Defining a role for CAPOM in the synapse. EJLB Foundation. $350,000. 2009-2012. Johnston M. Controlled trans-lymphatic delivery of chemotherapeutic agents for treating lymphatic metastasis in lung cancer. CIHR. $150,000. 2007-2010. Fawcett J. Elucidating the development of neural circuits involved in locomotion. NSERC. $290,115. 2007-2010. Giacomantonio C. Faculty of Medicine Clinical Scholar Award, Dalhousie University. $400,000. 2009-2014. Lee T. CD8+ T cell activation and effector mechanisms. NSERC. $250,000. 2009-2014. Lee T. Role of antibody in allograft vasculopathy. HSFC. $150,000. 2009-2012. 32 | Department of Surgery Lee T. The role of angiotensin II in myocardial inflammation. NSHRF. $150,000. 2008-2011. Stanish W. The effect of Car-Gel on knee cartilage regeneration. Private anonymous donor. $250,000. 2005-2010. Lee T. Etiology of allograft vasculopathy after cardiac transplantation: Role of pre-existing disease. HSFC. $150,000. 2008-2011. Stanish W. Effect of knee bracing on proprioception. Private anonymous donor. $50,000. 2002-2010. Lee T. Novel immunotherapy for the treatment of breast cancer metastases. CBCF. $120,000. 2008-2010. Stanish W. Biomechanical and neuromuscular characteristics during gait in moderate knee osteoarthritis. CIHR. $118,500. 2007-2010. Lee T, Alwayn I, Hirsch G, Hancock Friesen C, Légaré JF. Building research capacity at the Atlantic Centre for Tranplantation Research. Department of Surgery Program Support Grant. $150,000. 2009-2011. Stanish W. Biomechanical and neuromuscular characteristics during gait in moderate knee osteoarthritis: A framework for developing and evaluating non-invasive interventions. NSHRF. $39,500. 2007-2010. Légaré JF. Development of a quality report card in cardiac surgery. Capital Health Innovation Fund. $50,000. 2009-2010. Stanish W. Biomechanical assessment of the effect of BMP on bone and tendon healing. Private anonymous donor. $150,000. 2007-2010. Légaré JF. Role of angiotensin II in myocardial inflammation. NSHRF. $150,000. 2008-2011. Yanchar N. Canadian Injury Indicators Development Team: Policy indicators for children and youth. CIHR operating grant: Partnerships for Child and Youth Health Indicators. $150,000. 2008-2011. Légaré JF. SIRS steroids in cardiac surgery, randomized controlled trial. CIHR. $1,500,000. 2010-2014. Légaré JF. Mobilization of fibrocytes after cardiac surgery. CDHA. $15,000. 2010. Leighton R. Prospective randomized clinical study to evaluate the effects of less invasive stabilization system (LISS) plating techniques in distal femoral fractures. AO North America. $198,000. 2008-2010. McNeely D, Walling S. Butyrylcholinesterase: A potential diagnostic and therapeutic target for primary brain tumours. $14,994. 2009-2010. Morris DP. Assessment of bone-anchored hearing aid performance after temporal bone resection. Dalhousie Summer Studentship Grant Award. $20,000. 2009-2010. Morris DP. Faculty of Medicine Clinical Scholar Award, Dalhousie University. $400,000. 2006-2011. Morris SF. The vascular anatomy of bone flaps. CDHA. $15,000. 2010. Morris SF. Microsurgical breast reconstruction. BCF. $50,000. 2010. O’Blenes S. The importance of timing in the repair of myocardial infarction by transplantation of skeletal myoblasts: Defining the role and therapeutic potential of hepatocyte growth factor. Heart and Stroke Foundation. $100,000. 2008-2010. O’Blenes S, Hancock Friesen C, Légaré JF. Building a capacity for multidisciplinary translational research with the Cardiovascular Research Group. Department of Surgery Program Support Grant. $150,000. 20102012. Porter G. Towards improving access to quality colorectal cancer services across the cancer control continuum. CIHR. $1,497,513. 2007-2012. Porter G. A randomized trial of a patient-centred strategy to facilitate transition of breast cancer survivors’ routine follow-up from specialist to primary care. Canadian Breast Cancer Research Alliance. $740,662. 2006-2011. Porter G. Knowledge sharing award: Colorectal cancer research in Nova Scotia. NSHRF. $11,500. 2010. Porter G. Showcase and strategy: Moving forward with colorectal cancer research in Nova Scotia. CIHR. $11,500. 2010-2011. Porter G. Towards understanding and improving cancer screening practices in cancer survivors: systematic review and meta-analyisis. CIHR. $31,900. 2010-2011. Yanchar N. Faculty of Medicine Clinical Scholar Award, Dalhousie University. $400,000. 2008-2013. Yanchar N. IWK Research Associateship for the Department of Surgery and Division of Pediatric Opthalmology. $114,750. 2007-2010. Dal Surgery Research Committee Dal Surgery Undergraduate Education Committee Dal Surgery Postgraduate Education Committee Chair: Dr. Greg Hirsch Head, Cardiac Surgery Members: Dr. Ian Alwayn General Surgery Dr. Robert Brownstone Neurosurgery Dr. Michael Dunbar Orthopaedics Dr. James Fawcett Pharmacology Dr. Mark Glazebrook Orthopaedics Dr. Robert Hart ENT Dr. David Hoskin Pathology Dr. Thomas Issekutz Pediatrics /Immunology Dr. Paul Johnson General Surgery Dr. J.F. Légaré Cardiac Surgery Dr. Tim Lee Microbiology & Immunology Dr. Steve Morris Plastic Surgery Dr. Natalie Yanchar Pediatric General Surgery Elaine Marsh Coordinatior Chairs: Dr. Brock Vair General Surgery Dr. Chad Coles Orthopaedics Members: Dr. John Grantmyre Urology Dr. Greg Hirsch Cardiac Surgery Dr. Timothy Brown ENT Dr. Jason Williams Plastic Surgery Dr. Simon Walling Neurosurgery Dr. Gordon Buduhan Thoracic Surgery Dr. Min Lee Vascular Surgery Dr. Guy Brisseau Pediatric General Surgery Sheila Reid Coordinator Resident Member: Dr. Maria Brake ENT Student Member: Coleman Black Chair: Dr. Brock Vair General Surgery Members: Dr. Greg Bailly Urology Dr. Roger Baskett Cardiac Surgery Dr. Mark Walsh General Surgery Dr. Emad Massoud ENT Dr. William Oxner Orthopaedics Dr. Ken Wilson Plastic Surgery Dr. Daniel McNeely Neurosurgery Dr. Min Lee Vascular Surgery Dr. Guy Brisseau CORE Dr. James Ellsmere Atlantic Skills Centre Sheila Reid Coordinator Resident Members: Dr. Simon Frank General Surgery Dr. Lindsay McDonald General Surgery Dr. Greg Hirsch and Elaine Marsh would like to thank everyone for their advice, feedback and editing. We would like to thank our department’s leaders, Dr. David Kirkpatrick and Dr. Adrian Park, our contributing faculty profiled in this report, and most importantly the patients and their families for sharing so unselfishly their stories. A very special thanks to Heather Travis, RN (Kidney Transplant), Diana Lawlor, NP (Bariatric Clinic), Jennifer Muirhead, RN (Pediatric Orthopaedics) and Sheila Reid (Education Office). Printed by The Printer, Dartmouth, NS Dalhousie University – Faculty of Medicine Department of Surgery Research Office RM: 8-846, VG Site, 1278 Tower Road Halifax, Nova Scotia B3H 2Y9 TEL: 902-473-4615 • FAX: 902-473-7969