Material Safety Data Sheet

H0186
Material Safety Data Sheet
PROTECTIVE CLOTHING
RISK PHRASES
HAZARD WARNINGS
Toxic compound, do not ingest or inhale. Avoid all contact
with this material.
Environmental hazard.
This material is very toxic to aquatic organisms.
Irritating to skin, eyes, and the respiratory system.
CARCINOGEN. MINIMIZE EXPOSURE.
POSSIBLE MUTAGEN. MINIMIZE EXPOSURE.
Air and light sensitive material.
Section I.
Chemical Product and Company Identification
Chemical Name
Hydroquinone
Catalog Number
Supplier
H0186
TCI America
9211 N. Harborgate St.
Synonym
Portland OR
1,4-Dihydroxybenzene
1-800-423-8616
Chemical Formula
C 6H 6O 2
CAS Number
Section II.
In case of
Emergency
Call
123-31-9
Chemtrec®
(800) 424-9300 (U.S.)
(703) 527-3887
(International)
Composition and Information on Ingredients
Chemical Name
CAS Number
Hydroquinone
Percent (%)
Min. 99.0 (T)
123-31-9
Toxicology Data
TLV/PEL
This chemical is classified as a
Rat LD
carcinogen. There is no
Mouse LD
acceptable exposure limit for
Rat LD
a carcinogen.
mg/kg
This compound is classified as
Rat LD
50
(oral) 302 mg/kg
50
(oral) 245 mg/kg
50
(intraperitoneal) 170
50
(intravenous) 115 mg/kg
a possible mutagen. There is
no acceptable exposure limit
for a mutagen.
Section III.
Acute Health Effects
Hazards Identification
T o x ic if in g e s t e d o r in h a le d .
A v o id p r o lo n g e d c o n t a c t w it h t h is m a t e r ia l.
O v e r e x p o s u r e m a y r e s u lt in s e r io u s illn e s s o r
death.
Ir r it a t in g t o e y e s a n d s k in o n c o n t a c t . In h a la t io n c a u s e s ir r it a t io n o f t h e lu n g s a n d r e s p ir a t o r y s y s t e m . In f la m m a t io n o f
t h e e y e is c h a r a c t e r iz e d b y r e d n e s s , w a t e r in g , a n d it c h in g .
S k in in f la m m a t io n is c h a r a c t e r iz e d b y it c h in g , s c a lin g ,
reddening, or, occasionally, blistering.
Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
Chronic Health Effects
CARCINOGENIC EFFECTS : Carcinogenic by RTECS criteria.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Tumorigenic Effects.
Rat TDLo Oral 12875 mg/kg/103 weeks intermittent
TOXIC Effects:
Tumorigenic - Carcinogenic by RTECS criteria
Blood - Leukemia
Rat TDLo Oral 25750 mg/kg/2 years continuous
TOXIC Effects:
Tumorigenic - Carcinogenic by RTECS criteria
Blood - Leukemia
Rat TDLo Oral 174720 mg/kg/26 weeks continuous
TOXIC Effects:
Tumorigenic - Carcinogenic by RTECS criteria
Lung, Thorax, or Respiration - Tumors
Liver - Tumors
DEVELOPMENTAL TOXICITY : Reproductive Effects.
Rat TDLo Oral 667 mg/kg, female 11 days of pregnancy
TOXIC Effects:
Effects on Fertility - Post implantation mortality
Rat TDLo Subcutaneous 550 mg/kg, female 11 days prior to mating
TOXIC Effects:
Maternal Effects - Menstrual cycle changes or disorders
TDLo Subcutaneous 5100 mg/kg, male 51 days prior to mating
TOXIC Effects:
Paternal Effects - Testes, epididymis, sper duct
Paternal Effects - Prostate, seminal vessicale, Cowper's gland, accessory glands
Effects on Fertility - Male fertility index
Continued on Next Page
Printed 2/6/2007.
Emergency phone number
(800) 424-9300
H0186
Section IV.
Eye Contact
Hydroquinone
Page 2
First Aid Measures
C h e c k f o r a n d r e m o v e a n y c o n t a c t le n s e s . In c a s e o f c o n t a c t , im m e d ia t e ly f lu s h e y e s w it h p le n t y o f w a t e r f o r a t le a s t 1 5
minutes. Get medical attention.
Skin Contact
In c a s e o f c o n t a c t , im m e d ia t e ly f lu s h s k in w it h p le n t y o f w a t e r f o r a t le a s t 1 5 m in u t e s w h ile r e m o v in g c o n t a m in a t e d
c lo th in g a n d s h o e s .
W a s h c lo th in g b e fo r e r e u s e .
T h o r o u g h ly c le a n s h o e s b e fo r e r e u s e .
G e t m e d ic a l a tte n tio n
immediately.
Inhalation
If t h e v ic t im is n o t b r e a t h in g , p e r f o r m m o u t h - t o - m o u t h r e s u s c it a t io n . L o o s e n t ig h t c lo t h in g s u c h a s a c o lla r , t ie , b e lt o r
w a is t b a n d .
If b r e a t h in g is d if f ic u lt , o x y g e n c a n b e a d m in is t e r e d .
S e e k m e d ic a l a t t e n t io n if r e s p ir a t io n p r o b le m s d o n o t
improve.
Ingestion
IN D U C E V O M IT IN G b y s t ic k in g f in g e r in t h r o a t .
L o w e r t h e h e a d s o t h a t t h e v o m it w ill n o t r e e n t e r t h e m o u t h a n d t h r o a t .
L o o s e n t ig h t c lo t h in g s u c h a s a c o lla r , t ie , b e lt o r w a is t b a n d .
r e s u s c it a t io n .
If t h e v ic t im is n o t b r e a t h in g , p e r f o r m m o u t h - t o - m o u t h
E x a m in e t h e lip s a n d m o u t h t o a s c e r t a in w h e t h e r t h e t is s u e s a r e d a m a g e d , a p o s s ib le in d ic a t io n t h a t t h e
toxic material was ingested; the absence of such signs, however, is not conclusive.
Section V.
Flammability
Flash Points
Combustion Products
Fire Hazards
Explosion Hazards
Fire and Explosion Data
Auto-Ignition
May be combustible at high temperature.
165°C (329°F)
Flammable Limits
.
These products are toxic carbon oxides (CO, CO
2
499°C (930.2°F)
Not available.
).
Not available.
Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media
and Instructions
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
Consult with local fire authorities before attempting large scale fire-fighting operations.
Section VI.
Spill Cleanup
Instructions
Accidental Release Measures
T o x ic m a t e r ia l. E n v r io n m e n t a lly h a z a r d o u s m a t e r ia l. Ir r it a t in g m a t e r ia l. C a r c in o g e n ic m a t e r ia l. P o s s ib le m u t a g e n ic
material. Air and light sensitive material.
S t o p le a k if w it h o u t r is k . D O N O T g e t w a t e r in s id e c o n t a in e r . D O N O T t o u c h s p ille d m a t e r ia l. U s e w a t e r s p r a y t o r e d u c e
vap o rs.
P r e v e n t e n t r y in t o s e w e r s , b a s e m e n t s o r c o n f in e d a r e a s ; d ik e if n e e d e d .
E lim in a t e a ll s o u r c e s o f ig n it io n .
Consult federal, state, and/or local authorities for assistance on disposal.
Section VII.
Handling and Storage
Information
Handling and Storage
T O X IC . E N V IR O N M E N T A L H A Z A R D . IR R IT A N T . C A R C IN O G E N . P O S S IB L E M U T A G E N . A IR A N D L IG H T S E N S IT IV E . K e e p lo c k e d
up.
K e e p a w a y fro m h e a t.
c o o l p la c e .
M e c h a n ic a l e x h a u s t r e q u ir e d .
W h e n n o t in u s e , t ig h t ly s e a l t h e c o n t a in e r a n d s t o r e in a d r y ,
A v o id e x c e s s iv e h e a t a n d lig h t . D O N O T in g e s t . D o n o t b r e a t h e d u s t . W e a r s u it a b le p r o t e c t iv e c lo t h in g . If
ingested, seek medical advice immediately and show the container or the label. Treat symptomatically and supportively.
Always store away from incompatible compounds such as oxidizing agents, alkalis (bases).
Section VIII.
Engineering Controls
Exposure Controls/Personal Protection
U s e p r o c e s s e n c lo s u r e s , lo c a l e x h a u s t v e n tila tio n , o r o th e r e n g in e e r in g c o n tr o ls to k e e p a ir b o r n e le v e ls b e lo w
r e c o m m e n d e d e x p o s u r e lim it s .
If u s e r o p e r a t io n s g e n e r a t e d u s t , f u m e o r m is t , u s e v e n t ila t io n t o k e e p e x p o s u r e t o
airborne contaminants below the exposure limit.
Personal Protection
S p la s h g o g g le s .
L a b c o a t.
in h a la t io n o f t h e p r o d u c t .
D u s t r e s p ir a t o r .
B o o ts .
G lo v e s .
A M S H A / N IO S H a p p r o v e d r e s p ir a t o r m u s t b e u s e d t o a v o id
S u g g e s t e d p r o t e c t iv e c lo t h in g m ig h t n o t b e s u f f ic ie n t ; c o n s u lt a s p e c ia lis t B E F O R E h a n d lin g
this product.
Exposure Limits
This chemical is classified as a carcinogen. There is no acceptable exposure limit for a carcinogen.
This compound is classified as a possible mutagen. There is no acceptable exposure limit for a mutagen.
Section IX.
Physical state @ 20°C
Physical and Chemical Properties
S o lid . (W h ite , C ry s ta l to C ry s ta llin e
Solubility
Not available.
Powder.)
Specific Gravity
Molecular Weight
1.332 (water=1)
110.11
Partition Coefficient
Log K
ow
: 0.59
Boiling Point
285°C (545°F)
Vapor Pressure
1 mmHg @ 132°C
Melting Point
171°C (339.8°F)
Vapor Density
3.81 (Air = 1)
Not available.
Volatility
Not available.
Not available.
Odor
Not available.
Not available.
Taste
Not available.
Refractive Index
Critical Temperature
Viscosity
Continued on Next Page
Printed 2/6/2007.
Emergency phone number
(800) 424-9300
H0186
Section X.
Stability
Conditions of Instability
Incompatibilities
Section XI.
RTECS Number
Routes of Exposure
Toxicity Data
Hydroquinone
Stability and Reactivity Data
This material is stable if stored under proper conditions. (See Section VII for instructions)
Avoid excessive heat and light.
Reactive with strong oxidizing agents, strong alkalis (bases).
Toxicological Information
MX3500000
Eye Contact. Ingestion. Inhalation.
Rat LD
50
Mouse LD
Chronic Toxic Effects
Page 3
(oral) 302 mg/kg
50
(oral) 245 mg/kg
Rat LD
50
(intraperitoneal) 170 mg/kg
Rat LD
50
(intravenous) 115 mg/kg
CARCINOGENIC EFFECTS : Carcinogenic by RTECS criteria.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Tumorigenic Effects.
Rat TDLo Oral 12875 mg/kg/103 weeks intermittent
TOXIC Effects:
Tumorigenic - Carcinogenic by RTECS criteria
Blood - Leukemia
Rat TDLo Oral 25750 mg/kg/2 years continuous
TOXIC Effects:
Tumorigenic - Carcinogenic by RTECS criteria
Blood - Leukemia
Rat TDLo Oral 174720 mg/kg/26 weeks continuous
TOXIC Effects:
Tumorigenic - Carcinogenic by RTECS criteria
Lung, Thorax, or Respiration - Tumors
Liver - Tumors
DEVELOPMENTAL TOXICITY : Reproductive Effects.
Rat TDLo Oral 667 mg/kg, female 11 days of pregnancy
TOXIC Effects:
Effects on Fertility - Post implantation mortality
Rat TDLo Subcutaneous 550 mg/kg, female 11 days prior to mating
TOXIC Effects:
Maternal Effects - Menstrual cycle changes or disorders
TDLo Subcutaneous 5100 mg/kg, male 51 days prior to mating
TOXIC Effects:
Paternal Effects - Testes, epididymis, sper duct
Paternal Effects - Prostate, seminal vessicale, Cowper's gland, accessory glands
Effects on Fertility - Male fertility index
Acute Toxic Effects
T o x ic if in g e s t e d o r in h a le d .
A v o id p r o lo n g e d c o n t a c t w it h t h is m a t e r ia l.
O v e r e x p o s u r e m a y r e s u lt in s e r io u s illn e s s o r
death.
Ir r it a t in g t o e y e s a n d s k in o n c o n t a c t .
In h a la t io n c a u s e s ir r it a t io n o f t h e lu n g s a n d r e s p ir a t o r y s y s t e m .
t h e e y e is c h a r a c t e r iz e d b y r e d n e s s , w a t e r in g , a n d it c h in g .
In f la m m a t io n o f
S k in in f la m m a t io n is c h a r a c t e r iz e d b y it c h in g , s c a lin g ,
reddening, or, occasionally, blistering.
Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
Section XII.
Ecotoxicity
Environmental Fate
Ecological Information
Not available.
H y d r o q u in o n e is b o t h a n a t u r a l a n d a n a n t h r o p o g e n ic c o m p o u n d . It m a y b e r e le a s e d t o t h e e n v ir o n m e n t a s a f u g it iv e
e m is s io n d u r in g it s p r o d u c t io n , f o r m u la t io n , a n d u s e , a s a c h e m ic a l in t e r m e d ia t e , p h o t o g r a p h ic c h e m ic a l, a n d s t a b iliz e r .
If r e le a s e d to s o il, h y d r o q u in o n e m a y b io d e g r a d e u n d e r a e r o b ic c o n d itio n s . It m a y a ls o b e r e m o v e d fr o m s o il b y
o x id a t io n p r o c e s s e s o r b y d ir e c t p h o t o ly s is o n t h e s u r f a c e . V o la t iliz a t io n o f h y d r o q u in o n e f r o m e it h e r m o is t o r d r y s o il is
n o t e x p e c t e d t o o c c u r t o a n y s ig n if ic a n t e x t e n t . H y d r o q u in o n e s h o u ld h a v e h ig h t o v e r y h ig h m o b ilit y in s o il. If r e le a s e d
t o w a t e r , h y d r o q u in o n e m a y d e g r a d e u n d e r b o t h a e r o b ic a n d a n a e r o b ic c o n d it io n s . B io c o n c e n t r a t io n in f is h a n d a q u a t ic
o r g a n is m s is n o t e x p e c t e d t o b e a n im p o r t a n t f a t e p r o c e s s , n o r w ill it a d s o r b t o s e d im e n t a n d s u s p e n d e d o r g a n ic m a t t e r .
H y d r o q u in o n e w ill u n d e r g o d ir e c t p h o to ly s is in w a te r , a n d it m a y b e d e g r a d e d in w a te r b y o x id a tiv e p r o c e s s e s .
V o la t iliz a t io n o f h y d r o q u in o n e f r o m w a t e r t o t h e a t m o s p h e r e w ill b e t o o s lo w t o b e e n v ir o n m e n t a lly im p o r t a n t . If r e le a s e d
t o t h e a t m o s p h e r e , h y d r o q u in o n e w ill u n d e r g o d ir e c t p h o t o c h e m ic a l d e g r a d a t io n . It m a y u n d e r g o a t m o s p h e r ic r e m o v a l
b y t h e r e a c t io n w it h p h o t o c h e m ic a lly p r o d u c e d h y d r o x y l r a d ic a ls a t a n e s t im a t e d h a lf - lif e o f 1 6 .8 h r s . H y d r o q u in o n e m a y
a ls o b e r e m o v e d f r o m t h e a t m o s p h e r e b y w e t d e p o s it io n p r o c e s s e s . O c c u p a t io n a l e x p o s u r e t o h y d r o q u in o n e m a y o c c u r
by dermal contact. Members of the general population who develop their own film may be exposed to hydroquinone.
Section XIII.
Waste Disposal
Disposal Considerations
R e c y c le t o p r o c e s s , if p o s s ib le . C o n s u lt y o u r lo c a l r e g io n a l a u t h o r it ie s . Y o u m a y b e a b le t o d is s o lv e o r m ix m a t e r ia l w it h
a c o m b u s t ib le s o lv e n t a n d b u r n in a c h e m ic a l in c in e r a t o r e q u ip p e d w it h a n a f t e r b u r n e r a n d s c r u b b e r s y s t e m . O b s e r v e a ll
federal, state and local regulations when disposing of the substance.
Continued on Next Page
Printed 2/6/2007.
Emergency phone number
(800) 424-9300
H0186
Section XIV.
DOT Classification
Hydroquinone
Page 4
Transport Information
Not a DOT controlled material (United States).
PIN Number
Not available.
Proper Shipping Name
Not available.
Packing Group (PG)
Not available.
DOT Pictograms
Section XV.
TSCA Chemical Inventory
(EPA)
WHMIS Classification
(Canada)
EINECS Number (EEC)
EEC Risk Statements
Other Regulatory Information and Pictograms
This compound is
ON the EPA Toxic Substances Control Act (TSCA) inventory list.
On DSL
204-617-8
R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.
R36/37/38- Irritating to eyes, respiratory system and skin.
R45- May cause cancer.
R46- May cause heritable genetic damage.
R47- May cause birth defects.
R50- Very toxic to aquatic organisms.
Japanese Regulatory Data
Section XVI.
ENCS No. 3-543
Other Information
Version 1.0
Validated on 2/6/2007.
Printed 2/6/2007.
Notice to Reader
TCI laboratory chemicals are for research purposes only and are NOT intended for use as drugs, food additives, households, or pesticides. The information herein is believed to be correct, but does not
claim to be all inclusive and should be used only as a guide. Neither the above named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the
information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All chemical reagents must be handled with the recognition that their chemical,
physiological, toxicological, and hazardous properties have not been fully investigated or determined. All chemical reagents should be handled only by individuals who are familiar with their potential
hazards and who have been fully trained in proper safety, laboratory, and chemical handling procedures. Although certain hazards are described herein, we can not guarantee that these are the only hazards
which exist. Our MSDS sheets are based only on data available at the time of shipping and are subject to change without notice as new information is obtained. Avoid long storage periods since the
product is subject to degradation with age and may become more dangerous or hazardous. It is the responsibility of the user to request updated MSDS sheets for products that are stored for extended
periods. Disposal of unused product must be undertaken by qualified personnel who are knowledgeable in all applicable regulations and follow all pertinent safety precautions including the use of
appropriate protective equipment (e.g. protective goggles, protective clothing, breathing equipment, facial mask, fume hood). For proper handling and disposal, always comply with federal, state, and local
regulations.
Printed 2/6/2007.