UNIVERSITY OF PENNSYLVANIA PERELMAN SCHOOL OF MEDICINE Curriculum Vitae

Transcription

UNIVERSITY OF PENNSYLVANIA – PERELMAN SCHOOL OF MEDICINE
Curriculum Vitae
October, 2012
Andrea Beth Troxel, Sc.D.
Office Address:
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania, School of Medicine
632 Blockley Hall, 423 Guardian Drive
Philadelphia, Pennsylvania 19104-6021
Telephone:
FAX:
E-mail:
(215) 573-0659
(215) 573-4865
[email protected]
Education:
1991
1995
B.S.
Sc.D.
Yale University (Applied Mathematics) cum laude
Harvard School of Public Health (Biostatistics)
Postgraduate Training and Fellowship Appointments:
1995 – 1997
Postdoctoral Fellow and Statistical Research Associate, Southwest Oncology
Group, Fred Hutchinson Cancer Research Center, Seattle, Washington
Military Service:
None
Faculty Appointments:
1997 – 2000
Assistant Professor of Clinical Public Health, Herbert Irving Comprehensive
Cancer Center, Division of Biostatistics, Mailman School of Public Health,
Columbia University, New York, NY
2000 – 2003
Assistant Professor of Biostatistics, Department of Biostatistics, Mailman
School of Public Health, Columbia University, New York, NY
2003 – 2006
Assistant Professor of Biostatistics at the Hospital of the University of
Pennsylvania, Department of Biostatistics and Epidemiology, University of
Pennsylvania School of Medicine
2006 – 2011
Associate Professor of Biostatistics at the Hospital of the University of
Pennsylvania, Department of Biostatistics and Epidemiology, University of
2011 – present
Professor of Biostatistics at the Hospital of the University of Pennsylvania,
Department of Biostatistics and Epidemiology, University of Pennsylvania
School of Medicine
Troxel, Andrea B., Sc.D.
2
Hospital and Administrative Appointments:
2003 – present
Member, Graduate Group in Epidemiology and Biostatistics, Biomedical
Graduate Studies Program, University of Pennsylvania School of Medicine
2003 – present
Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University
of Pennsylvania School of Medicine
2008 – present
Director of Biostatistics, Leonard Davis Institute Center for Health Incentives
and Behavioral Economics, University of Pennsylvania School of Medicine
2011 – present
Associate Fellow, Center for Health Behavior Research, University of
2011 – present
Associate Director for Faculty Affairs, Division of Biostatistics, Department of
Biostatistics and Epidemiology, University of Pennsylvania School of Medicine
2012 – present
Investigator, Center for Pharmacoepidemiology Research and Training,
University of Pennsylvania School of Medicine
Specialty Certification:
n/a
Licensure:
n/a
Awards, Honors and Membership in Honorary Societies:
1991 – 1993
1992 – 1994
2002 – 2006
2006
2008 – 2009
2010
2010
2010
National Institutes of Health Training Grant
Harvard University Teaching Fellow
Sigma Xi
Circulation Best Paper Award in Population Science, for Stettler, N., Stallings
V.A., Troxel A.B., Zhao J., Schinnar R., Nelson S.E., Ziegler E.E. and Strom
B.L. Weight gain in the first week of life and overweight in adulthood: a cohort
study of European-American subjects fed infant formula. Circulation, 111:
1897-903, 2005.
Fellow, Columbia University Institute for Scholars at Reid Hall, Paris, France
British Medical Journal Group Award for “Getting Research Into Practice,” for
Volpp K.G., Troxel A.B., Pauly M.V., Glick H.A., Puig A., Asch D.A., Galvin
R., Zhu J., Wan F., DeGuzman J., Corbett E., Weiner J. and Audrain-McGovern
J. A randomized, controlled trial of financial incentives for smoking cessation.
New England Journal of Medicine, 360: 699-709, 2009.
Society of General Internal Medicine Research Paper of the Year, for Volpp
K.G., Troxel A.B., Pauly M.V., Glick H.A., Puig A., Asch D.A., Galvin R., Zhu
J., Wan F., DeGuzman J., Corbett E., Weiner J. and Audrain-McGovern J. A
randomized, controlled trial of financial incentives for smoking cessation. New
England Journal of Medicine, 360: 699-709, 2009.
The National Psoriasis Foundation Top Research Findings for 2010, Mehta
N.N., Azfar R.S., Shin D.B., Neimann A.L., Troxel A.B. and Gelfand J.M.
Patients with severe psoriasis are at increased risk of cardiovascular mortality:
Cohort study using General Practice Research Database. European Heart
2010
2010
2012
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Journal, 31: 1000-6, 2010.
The National Psoriasis Foundation Top Research Findings for 2010, Kurd
S.K., Troxel A.B., Crits-Christoph P. and Gelfand J.M. The risk of depression,
anxiety and suicidality in patients with psoriasis: A population-based cohort
study. Archives of Dermatology, 146: 891-5, 2010.
Excellence in Teaching Epidemiology Award, Center for Clinical Epidemiology
and Biostatistics, University of Pennsylvania School of Medicine
Elected Fellow, American Statistical Association
Membership in Professional and Scientific Societies and Other Professional Activities:
International:
1996
Member, Workshop on Missing Data in Quality of Life Research in Cancer
Clinical Trials: Practical and Methodological Issues, Swiss Group for Clinical
Cancer Research
1999 – present
International Biometrics Society
National:
1997
1999 – present
2001
2002 – 2004
2003
2005 – 2006
2005
2005
2005 – 2009
2007 – present
2008 – 2012
2008 – present
2009 – 2011
Member, Phase II Clinical Trials of New Chemopreventive Agents, NIH Review
Panel and Board, NCI
Member, American Statistical Association
Member, Minimally Invasive Surgical Therapies for Benign Prostatic
Hypertrophy, NIH Review Panel and Board, NIDDK
Member, Chronic Prostatitis Collaborative Research Network (CPCRN),
External Advisory Committee, NIDDK
Member, Avon/NCI Progress for Patients Award Program
Ad hoc member, Biostatistical Methods and Research Design study section,
Health of Populations IRG, NIH
Ad hoc member, Developmental Therapeutics study section, Oncological
Sciences IRG, NIH
Ad hoc member, Subcommittee E (Cancer Epidemiology, Prevention and
Control), National Cancer Institute IRG, NIH
Ad hoc member, Epidemiology of Cancer (EPIC) study section, Health of
Populations IRG, NIH
Chair, Data and Safety Monitoring Board, DAIDS-ES 10401 (Antiviral Activity
of Peg-IFN-a-2A in Chronic HIV-1 Infection; L. Montaner, PI)
Member, Blood Products Advisory Committee, Food and Drug Administration
Member, Data and Safety Monitoring Board, Terumo Heart DH-003 (Evaluation
of the Safety and Effectiveness of the DuraHeart Left Ventricular Assist System
in Patients Awaiting Transplantation)
Member, EPIC Member Conflict Special Emphasis Panel (ZRG1 PSE-B 03 M)
2010
2010 – 2011
2011 – present
2011 – present
4
Member, Education Advisory Committee, ENAR
Ad hoc member, Cancer Biomarkers study section, Oncology 2 – Translational
Clinical IRG, NIH
Chair, Data and Safety Monitoring Board, PNAT (Pharmacogenetics of Nicotine
Addiction Treatment; C. Lerman, PI)
Chair, TREC Randomized Clinical Trials Methods Working Group
Local:
2004 – 2009
2004 – present
2009 – 2011
2009 – present
2009 – 2011
2011 – present
2011 – present
Member, Data and Safety Monitoring Board, UPCC 11102/03104 (R.
Vonderheide, PI)
Member, Philadelphia Chapter, American Statistical Association
Member, Scientific Monitoring Committee, UPCC 08107 (R. Vonderheide, PI)
Member, Safety Monitoring Committee, UPCC 05609 (R. Vonderheide, PI)
Chair, Data and Safety Monitoring Board, Smart Steps/Mind
Your Body (N. Stettler, PI)
Member, Safety Monitoring Committee, UPCC 03111 (R. Vonderheide, PI)
Member, Data and Safety Monitoring Board, UPCC 14211 (R. Vonderheide, PI)
Editorial Positions:
1998 – present
1998 – present
1998 – present
1998 – present
1998 – present
1999 – present
1999 – present
1999 – present
2000 – present
2000 – present
2002 – present
2005 – present
2005 – present
2006 – present
2006 – present
2007 – present
2007 – present
2007 – present
2008 – present
Reviewer
Reviewer
Reviewer
Reviewer
Reviewer
Reviewer
Reviewer
Reviewer
Reviewer
Reviewer
Reviewer
Reviewer
Associate Editor
Reviewer
Reviewer
Reviewer
Reviewer
Reviewer
Reviewer
Applied Statistics
Biometrics
Journal of the American Medical Women’s Association
Journal of Clinical Oncology
Journal of the American Statistical Association
American Journal of Public Health
Quality of Life Research
Statistics in Medicine
Communication in Statistics
Controlled Clinical Trials
Biometrical Journal
Fertility and Sterility
Statistics in Medicine
Journal of the National Cancer Institute
Scandinavian Journal of Statistics
Journal of Clinical Investigation
Journal of Biopharmaceutical Statistics
Pharmacoepidemiology and Drug Safety
Journal of the Royal Statistical Society, Series B
2010 – present
2010 – present
2011 – present
2012 – present
Reviewer
Reviewer
Associate Editor
Statistical Editor
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Biostatistics
Computational Statistics and Data Analysis
BMC Medical Research Methodology
Journal of Clinical Oncology
Academic and Institutional Committees:
2003 – 2008
Member, Admissions Committee, Division of Biostatistics, Department of
2004 – 2006
Member (Chair, 2005-2006), Curriculum Committee, Division of Biostatistics,
School of Medicine
Member, Appointments Committee, Center for Clinical Epidemiology and
Biostatistics, University of Pennsylvania School of Medicine
2004 – present
(on leave
2008 – 2009)
2005
2006 – present
(on leave
2008 – 2009)
2006 – 2008
2011 – present
2006 – present
(on leave
2008 – 2009)
2010 – present
2011 – present
2011 – present
2011 – 2014
Member, Summer Fellowship Committee, Center for Clinical Epidemiology and
Biostatistics, University of Pennsylvania School of Medicine
Chair, Qualifying Examination Committee, Division of Biostatistics,
School of Medicine
Member, Committee on Appointments and Promotions (COAP), Department of
Member, Gender Equity Council, University of Pennsylvania School of
Medicine
Member, Recruitment Committee, Division of Biostatistics, Department of
Member, Committee on Appointments and Promotions (COAP), Department of
Member, Student-Faculty Relations Committee, Division of Biostatistics,
School of Medicine
Member, Hearings List, Faculty Grievance Commission, University of
Pennsylvania
2012 – present
Member, Qualifying Examination Committee, Department of Biostatistics
2012 – present
Member, Graduate Programs Executive Committee, Department of Biostatistics,
6
Major Academic and Clinical Teaching Responsibilities:
2003 – 2006
2003 – 2006
2004 – 2006
2004 – 2005
PhD Thesis Committee Member for Jiameng Zhang, Department of Biostatistics
and Epidemiology, University of Pennsylvania School of Medicine
PhD Thesis Director for Denise A. Esserman, Columbia University Mailman
School of Public Health
MSCE Thesis Committee Member for Andrea Cheville, MD, Department of
Academic Advisor for Michal Magid-Slav, Department of Biostatistics and
Epidemiology, University of Pennsylvania School of Medicine
2004 – 2005
MSCE Thesis Committee Member for Andrew Ochroch, MD, Department of
2004 – 2006
MSCE Thesis Committee Member for Andrea Neimann, MD, Department of
2004 – 2008
MSCE Thesis Committee Member for Nananamibia Smith, MD, Department of
Spring 2004
Instructor, Consulting II (BSTA 691), Department of Biostatistics and
Course Director, Applied Regression Models for Categorical Data (EP 622),
School of Medicine
Course Director, Independent Study: Applied Regression Models for
Categorical Data (EP 999), Department of Biostatistics and Epidemiology,
Lecturer, Unequal Treatment: Health in America (HSOC 015), Health and
Societies Program, University of Pennsylvania School of Arts and Sciences
Lecturer, Independent Study: Ameliorating Health Disparities One Step at a
Time (HSOC 499.036), Health and Societies Program, University of
Pennsylvania School of Arts and Sciences
Fall 2004
Fall 2004
Fall 2004
Fall 2004
2005 – 2008
Academic Advisor for Hanjoo Kim, Department of Biostatistics and
2005 – 2008
MSCE Thesis Committee Member for Noelle Frey, MD, Department of
Spring 2005
Lecturer, Independent Study: Ameliorating Health Disparities One Step at a
Time (HSOC 499.036), Health and Societies Program, University of
Pennsylvania School of Arts and Sciences
Spring 2005
Lecturer, Undergraduate Urban Research Course (CPLN 528/URBS 428),
Institute for Urban Research, University of Pennsylvania School of Arts and
Sciences
Spring 2005
Instructor, Consulting II (BSTA 691), Department of Biostatistics and
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Spring 2005
Facilitator, BGS Bioethics Workshop for 3rd Year Students, University of
Fall 2005
School of Medicine
2006 – 2008
MSCE Thesis Committee Member for Daniel Elliott, MD, Department of
2006 – 2008
MSCE Thesis Committee Member for Kimberly Forde, MD, Department of
2006 – 2008
MSCE Thesis Committee Member for Steven Halbert, MD, Department of
2006 – 2009
MSCE Thesis Committee Member for Chrysalyne Schmults, MD, Department
of Biostatistics and Epidemiology, University of Pennsylvania School of
Medicine
2006 – 2011
Secondary Mentor, Scarlett Bellamy, ScD, Department of Biostatistics and
Spring 2006
Course Director, Independent Study: Longitudinal Data Analysis (EP 999),
School of Medicine
Fall 2006
School of Medicine
2007 – 2008
MSCE Thesis Committee Member for Robert Sutton, MD, Department of
2007 – 2009
MSCE Thesis Committee Member for Shanu Kohli Kurd, MD, Department of
2007 – present
Primary Mentor, Wei-Ting Hwang, PhD, Department of Biostatistics and
Spring 2007
Lecturer, Clinical Trials (EP 630), Department of Biostatistics and
Spring 2007
Lecturer, Fundamentals of Pharmacology II (Pharm 623), Department of
Pharmacology, University of Pennsylvania School of Medicine
Summer 2007
Lecturer, Advanced Topics in Clinical Epidemiology (EP 640), Department of
Fall 2007
School of Medicine
Fall 2007
Course Director, Applied Survival Analysis (EP 623), Department of
8
2008
MSCE Thesis Committee Member for Stephen Keefe, MD, Department of
2008 – present
PhD Thesis Committee Member for Kimberly Forde, MD, Department of
Spring 2008
Lecturer, Clinical Trials (EP 630), Department of Biostatistics and
Spring 2008
Lecturer, Fundamentals of Pharmacology II (Pharm 623), Department of
Pharmacology, University of Pennsylvania School of Medicine
Summer 2008
2009 – present
MSCE Thesis Committee Member for Peter de Blank, MD, Department of
2009 – 2010
PhD Thesis Co-Director for Seunghee Baek, MS, Department of Biostatistics
2009 – 2011
Academic Advisor for Cristin Scott, Department of Biostatistics and
Fall 2009
School of Medicine
2010 – present
MSCE Thesis Committee Member for Alexis Ogdie, MD, Department of
2010 – 2011
PhD Thesis Committee Member for Steffanie Halberstadt, MS, Department of
2010 – 2011
PhD Thesis Committee Member for Hong Wan, MS, Department of Biostatistics
2010 – 2012
PhD Thesis Director for Kaijun Liao, MS, Department of Biostatistics and
Spring 2010
Lecturer, Applied Regression Analysis for Health Policy Research (HPR 608),
Master of Science in Health Policy Program, University of Pennsylvania School
of Medicine
Spring 2010
Facilitator, Biomedical Graduate Studies Responsible Conduct in Research
Workshop for 4th Year Students, University of Pennsylvania School of Medicine
Summer 2010
2011 – present
Primary Mentor, Scarlett Bellamy, ScD, Department of Biostatistics and
2011 – present
PhD Thesis Director for Kay-See Tan, MS, Department of Biostatistics and
2011 – present
MSCE Thesis Committee Member for Junko Takeshita, MD, Department of
9
2011 – present
MSCE Thesis Committee Member for Meera Nair, MD, Department of
Spring 2011
Course Director, Longitudinal Data Analysis (BSTA 656), Department of
Summer 2011
Spring 2012
Course Director, Longitudinal Data Analysis (BSTA 656), Department of
Fall 2012
School of Medicine
2012 – present
Academic Advisor for Pixu Shi, Department of Biostatistics and Epidemiology,
2012 – present
MSCE Thesis Committee Member for Ashley Ford, MD, Department of
2012 – present
MSCE Thesis Committee Member for Tamara Miller, MD, Department of
Lectures by invitation: (past five years only)
2/28/2005
3/2/2005
3/5/2005
8/9/2005
7/29/2007
8/3/2008
10/7/2008
“Frailty Models for Quality of Life Data in Oncology” – Fred Hutchinson
Cancer Research Center, Seattle, WA
“Modeling Quality of Life Data with Missing Values” – Division of Cancer
Prevention and Control, National Cancer Institute, Bethesda, MD
“Modeling Quality of Life Data with Missing Values” – Connecticut Chapter of
the American Statistical Association, Wallingford, CT
“Frailty Models for Quality of Life Data in Oncology” – Joint Statistical
Meetings, Minneapolis, MN
“Multivariate Normal Frailty Models for Multiple QOL Outcomes” – Joint
Statistical Meetings, Salt Lake City, UT
“Extensions of Frailty Models for Multivariate Grouped Survival Data” – Joint
Statistical Meetings, Denver, CO
“Early Phase Clinical Trials in Oncology” – Columbia University Institute for
Scholars at Reid Hall, Paris, France
10/17/2008
“An Index of Sensitivity to Nonignorability” – Ecole Doctorale “Epidémiologie
Sciences Sociales et Santé Publique,” Villejuif, France
1/6/2009
“Frailty Models for Quality of Life in Oncology” – Unit 780, Institut National de
la Santé et de la Récherche Médicale, Villejuif, France
“A New Pseudo-Likelihood for Longitudinal Binary Data with Nonignorable
Missingness” – Interuniversity Institute for Biostatistics and Statistical
Bioinformatics, Universiteit Hasselt, Diepenbeek, Belgium
1/16/2009
2/3/2009
2/26/2009
3/5/2009
3/10/2009
12/3/2010
4/13/2011
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“Pseudo-Likelihood Approaches for Binary Longitudinal Data with
Nonignorable Missingness” – Unit 897, Institut National de la Santé et de la
Récherche Médicale, Université Victor Segalen Bordeaux 2, Bordeaux, France
“Modeling Quality of Life Data with Missing Values” – Unitat de
Bioestadística I Bioinformàtica, Institut Català d’Oncologia, Barcelona, Spain
“Analysis of Quality of Life Data when Some Responses are Missing” –
Columbia University Institute for Scholars at Reid Hall, Paris, France
“Modeling Quality of Life Data with Missing Values” – International Agency
for Research on Cancer, Lyons, France
“A New Pseudo-Likelihood for Longitudinal Binary Data with Nonignorable
Missingness” – Department of Statistics, Florida State University, Tallahassee,
FL
“New Incentive Approaches for Adherence” – Department of Biostatistics,
University of Pennsylvania, Annual Conference on Statistical Issues in Clinical
Trials, Philadelphia, PA
Organizing roles in Scientific Meetings:
3/1999
8/14/2002
8/9/2005
ENAR meeting, Organized Invited Session 45, “New Developments in Analysis
of Quality of Life in Clinical Trials,” Atlanta, GA
JSM, Organized Invited Session 340, “Sensitivity Analysis for Longitudinal
Data,” New York, NY
JSM, Organized Topic Contributed Session 309, “Analyzing Quality of Life
Data in Clinical Trials,” Minneapolis, MN
Bibliography:
Research publications, peer reviewed:
1. Gribben J.G., Neuberg D., Freedman A.S., Pesek K., Troxel A.B. and Nadler L.M.:
Detection of residual lymphoma cells by PCR in peripheral blood is significantly less
predictive for relapse than evaluation of bone marrow. Blood 80: 337, 1992.
2. Saphner T., Troxel A.B., Tormey D.C., Neuberg D., Robert N.J., Pandya K.J.,
Edmonson J.H., Rosenbluth R.J. and Abeloff, M.D.: Phase II study of goserelin for
patients with postmenopausal metastatic breast cancer. Journal of Clinical Oncology
11: 1529-1535, 1993.
3. Bennett J.M., Troxel A.B., Gelman R., Falkson G., Coccia-Portugal M.D., Dreicer
R., Tormey D.C. and Rushing D.: Myelodysplastic syndrome and acute myeloid
leukemia secondary to mitolactol treatment in patients with breast cancer. Journal of
Clinical Oncology 12: 874-875, 1994.
4. Ramsey S.D., Etzioni R., Troxel A.B. and Urban N.: Optimizing sampling strategies
for estimating quality-adjusted life years. Medical Decision Making 17: 431-438,
1997.
5. Troxel A.B., Lipsitz S.R. and Brennan T.A.: Weighted estimating equations with
nonignorably missing response data. Biometrics 53: 857-869, 1997.
6. Monipour C.M., Savage M.J., Troxel A.B., Lovato L.C., Eisenberger M., Veith R.B.,
Higgins B., Skeel R., Yee M., Blumenstein B., Crawford E.D. and Meyskens F.L.:
Quality of life in advanced prostate cancer: results of a randomized therapeutic trial.
Journal of the National Cancer Institute 90: 1537-1544, 1998.
7. Troxel A.B.: A comparative analysis of quality of life data from a Southwest
Oncology Group randomized trial of advanced colorectal cancer. Statistics in
Medicine 17: 767-779, 1998.
8. Troxel A.B., Fairclough D.L., Curran D. and Hahn E.A.: Statistical analysis of
quality of life with missing data in cancer clinical trials. Statistics in Medicine 17:
653-666, 1998.
9. Troxel A.B., Harrington D.P. and Lipsitz S.R.: Analysis of longitudinal data with
non-ignorable non-monotone missing values. Applied Statistics 74: 425-438, 1998.
10. Troxel A.B., Lipsitz S.R. and Harrington D.P.: Marginal models for the analysis of
longitudinal measurements with nonignorable non-monotone missing data.
Biometrika 85: 661-672, 1998.
11. Grann V.R., Jacobson J.S., Sundararajan V., Albert S.M., Troxel A.B. and Neugut
A.I.: The quality of life associated with prophylactic treatment for women with
BRCA1/2 mutations. Cancer Journal from Scientific American 5: 283-292, 1999.
12. Kambham N., Taylor J.A., Troxel A.B. and Rubin M.A.: Atypical small acinar
proliferation in prostate needle biopsies: a clinically significant category. Journal of
Urologic Pathology 10: 177-179, 1999.
13. Papadopoulos K.P., Ayello J., Reiss R.F., Troxel A., Kaufman E., Vahdat L.T.,
Antman K.H. and Hesdorffer C.S.: CD34+ cell dose requirements for rapid
engraftment in a sequential high dose chemotherapy regimen of paclitaxel,
melphalan and cyclophosphamide, thiotepa and carboplatin (CTCb) with PBPC
support in metastatic breast cancer. Journal of Hematotherapy and Stem Cell
Research 8: 357-363, 1999.
14. Papadopoulos K.P., Balmaceda C., Fetell M., Kaufman E., Vahdat L.T., Bruce J.,
Sisti M., Isaacson S., DeLaPaz R., Savage D.G., Troxel A., Antman K.H. and
Hesdorffer C.S.: A Phase I study of BCNU, etoposide, and escalating-dose thiotepa
(BTE) with hematopeietic progenitor cell support in adults with recurrent and highrisk brain tumors. Journal of Neurooncology 44: 155-162, 1999.
11
15. Rowe D.R., Huang J., Kayton M.L., Thompson R., Troxel A., O'Toole K.M.,
Yamashiro D., Stolar C.J.H. and Kandel J.: Anti-VEGF antibody suppresses primary
tumor growth and metastasis in an experimental model of Wilms' tumor. Journal of
Pediatric Sugery 35: 30-33, 2000.
16. Brenin D.R., Manasseh D.M., El-Tamer M., Troxel A., Schnabel F., Ditkoff B.A.
and Kinne D.: Factors correlating with lymph node metastases in patients with T1
breast cancer. Annals of Surgical Oncology 8: 432-437, 2001.
17. Jacbson J.S., Troxel A.B., Evans J., Klaus L., Vahdat L.T., Kinne D., Lo K.M.,
Moore A., Rosenman P.J., Kaufman E.L., Neugut A.I. and Grann V.R.: Randomized
trial of black cohosh for the treatment of hot flashes among women with a history of
breast cancer. Journal of Clinical Oncology 19: 2739-2745, 2001.
18. Ovchinnikov I., Troxel A.B. and Swergold G.D.: Genomic characterization of recent
human LINE-1 insertions: evidence supporting random insertion. Genome Research
11: 2050-2058, 2001.
19. Papadopoulos K.P., Gorin M.J., Huang M., Troxel A.B., Kaufman E., Balmaceda
C.M., Vahdat L.T. and Hesdorffer C.S.: The pharmacokinetics and
pharmacodynamics of high-dose paclitaxel monotherapy (825 mg/m2 continuous
infusion over 24h) with hematopoietic support in women with metastatic breast
cancer. Cancer Chemotherapy Pharmacology 47: 45-60, 2001.
20. Nichols G., deCastro K., Wei L.X., Griffin M., Lin M., Oratzi A., Murty A.V.V.S.,
Troxel A., Vahdat L. and Hesdorffer C.: Therapy-related myelodysplastic syndrome
after autologous stem cell transplantation for breast cancer. Leukemia 16: 1673-1679,
2002.
21. Troxel A.B.: Techniques for incorporating longitudinal measurements into analyses
of survival data from clinical trials. Statistical Methods in Medical Research 11: 237245, 2002.
22. Vahdat L.T., Balmaceda C., Papadopoulos K., Frederick D., Donovan D., Sharpe E.,
Kaufman E., Savage D., Tiersten A., Nichols G., Haythe J., Troxel A., Antman K.
and Hesdorffer C.S.: Phase II trial of sequential high-dose chemotherapy with
paclitaxel, melphalan and cyclophosphamide, thiotepa and carboplatin with
peripheral blood progenitor support in women with responding metastatic breast
cancer. Bone Marrow Transplantation 30(3): 149-155, 2002.
23. El-Tamer M., Komenaka I., Curry S., Troxel A.B., Ditkoff B.A. and Schnabel F.R.:
Pulse oximeter changes with sentinel lymph node biopsy in breast cancer. Archives
of Surgery 138: 1257-1260, 2003.
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24. Hershman D., Weinberg M., Rosner Z., Alexis K., Tiersten A., Grann V.R., Troxel
A. and Neugut A.I.: Ethnic neutropenia and treatment delay in African American
women undergoing chemotherapy for early-stage breast cancer. Journal of the
National Cancer Institute 95: 1545-1548, 2003.
25. Qu X., Yu J., Bhagat G., Furuya N., Hibshoosh H., Troxel A.B., Rosen J., Eskeline
E.L., Mizushima N., Ohsumi Y., Cattoetti G. and Levine B.: Promotion of
tumorigenesis by heterozygous disruption of the beclin1 autophagy gene. Journal of
Clinical Investigation 11: 1809-1820, 2003.
26. Talbot S.M., Keohan M.L., Hesdorffer M., Orrico R., Bagiella E., Troxel A.B., and
Taub R.N.: A Phase II trial of temozolomide in patients with unresectable or
metastatic soft tissue sarcoma. Cancer 98: 1942-1946, 2003.
27. Tiersten A.D., Nelson C., Talbot S., Vahdat L., Fine R., Troxel A., Brafman L.,
Shriberg L., Antman K. and Petrylak D.P.: A Phase II trial of docetaxel and
estramustine in patients with refractory metastatic breast carcinoma. Cancer 97: 537544, 2003.
28. El-Tamer M., Russo D., Troxel A., Bernadino L.P., Mazziotta R., Estabrook A.,
Ditkoff B.A. Schnabel R. and Mansukhani, M.: Survival and recurrence after breast
cancer in BRCA/2 mutation carriers. Annals of Surgical Oncology 11: 157-164,
2004.
29. El-Tamer M.B., Komenaka I.K., Troxel A., Li H., Joseph K.A., Ditkoff B.A.,
Schnabel F.R. and Kinne D.W.: Men with breast cancer have better disease-specific
survival than women. Archives of Surgery 139: 1079-1082, 2004.
30. Joseph K.A., El-Tamer M., Komenaka I., Troxel A., Ditkoff B.A., Schnabel F.:
Predictors of nonsentinel node metastasis in patients with breast cancer after sentinel
node metastasis. Archives of Surgery 139: 648-351, 2004.
31. Komenaka S.K., El-Tamer M.B., Troxel A., Hamele-Bena D., Joseph K.A.,
Horowitz E., Ditkoff B.A. and Schnabel R.: Pure mucinous carcinoma of the breast.
American Journal of Surgery 187: 528-532, 2004.
32. Tiersten A., Ng Y.Y., Pile-Spellman E., Nelsen C., Noguera-Irizarry W., Brafman R.,
Russo D., Troxel A. and Johnson A.: Relationship between mammographic breast
density and tamoxifen in women with breast cancer. Breast Journal 10: 313-317,
2004.
33. Tiersten A., Wo J., Jacobson C., Weitzman A., Horwich T., Hesdorffer C., Savage D.
and Troxel A.: Cardiac toxicity observed in association with high-dose
cyclophosphamide-based chemotherapy for metastatic breast cancer. Breast 13: 341346, 2004.
13
34. Tiersten A.D., Selleck M.J., Hershman D.L., Smith D., Resnik E.E., Troxel A.B.,
Brafman L.B. and Shriberg L.: Phase II study of topotecan and paclitaxel for
recurrent, persistent or metastatic cervical carcinoma. Gynecologic Oncology 92:
635-638, 2004.
35. Troxel A.B. and Esserman D.A.: Frailty models for quality of life in oncology.
Journal of Biopharmaceutical Statistics 14: 145-154, 2004.
36. Troxel A.B., Ma G. and Heitjan D.F.: An index of sensitivity to nonignorability
Statistica Sinica 14: 1221-1237, 2004.
37. Grann V.R., Jacobson J.S., Karp J., Hershman D., Troxel A.B., Myers K. and
Neugut A.I.: Barriers to minority participation in breast cancer prevention trials.
Cancer 104: 374-379, 2005.
38. Grann V.R., Troxel A.B., Zojwalla N., Jacobson J.S., Hershman D. and Neugut A.I.:
Hormone receptor status and survival in a population-based cohort of patients with
breast cancer. Cancer 103: 2241-2251, 2005.
39. Joe A.K., Memeo L., McKoy J., Mansukhani M., Liu H., Avila-Bront A., Romero J.,
Li H., Troxel A. and Hibshoosh H.: Cyclin D1 overexpression is associated with
estrogen receptor expression in Caucasian but not African-American breast cancer.
Anticancer Research 25: 273-281, 2005.
40. Ma G., Troxel A.B. and Heitjan D.F.: An index of local sensitivity to nonignorable
dropout in longitudinal modeling. Statistics in Medicine 24: 2129-2150, 2005.
41. Park J.H., Gopishetty S., Szewczuk L.M., Troxel A.B., Harvey R.G. and Penning
T.M.: Formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dGuo) by PAH oquinones: involvement of reactive oxygen species and copper(II)/copper(I) redox
cycling. Chemical Research in Toxicology 18: 1026-1037, 2005.
42. Stettler N., Stallings V.A., Troxel A.B., Zhao J., Schinnar R., Nelson S.E., Ziegler
E.E. and Strom B.L.: Weight gain in the first week of life and overweight in
adulthood: a cohort study of European-American subjects fed infant formula.
Circulation 111: 1897-903, 2005.
43. Stubblefield M.S., Vahdat L.T., Balmaceda C.M., Troxel A.B., Hesdorffer C.S. and
Gooch C.L.: Glutamine as a neuroprotective agent in high-dose paclitaxel-induced
peripheral neuropathy: a clinical and electrophysiologic study. Clinical Oncology 17:
271-276, 2005.
14
44. Brown T.T., Quain R.D., Troxel A.B. and Gelfand J.M.: The epidemiology of
sunburn in the U.S. population in 2003. Journal of the American Academy of
Dermatology 55: 577-583, 2006.
45. Clark J., Lambertson C., Gelfand R. and Troxel A.: Optimization of oxygen tolerance
extension in rats by intermittent exposure. Journal of Applied Physiology 100: 869879, 2006.
46. Fisher J.A., Fikry C.R. and Troxel A.B.: Cutting cost and increasing access to
colorectal cancer screening: another approach to following the guidelines. Cancer
Epidemiology, Biomarkers and Prevention 15: 108-113, 2006.
47. Gelfand J.M., Neimann A.L., Shin D.B., Wang X., Margolis D.J. and Troxel A.B.:
The risk of myocardial infarction in patients with psoriasis. Journal of the American
Medical Association 296: 1735-1741, 2006.
48. Gelfand J.M., Shin D.B., Neimann A.L., Wang X., Margolis D.J. and Troxel A.B.:
The risk of lymphoma in patients with psoriasis. Journal of Investigative
Dermatology 126: 2194-2201, 2006.
49. Gorin S.S., Ashford A.R., Lantigua R., Hossain A., Desai M., Troxel A., Neugut A.I.
and Gemson D.: Effectiveness of academic detailing on breast cancer screening
among primary care physicians in an underserved community. Journal of the
American Board of Family Medicine 19: 110-121, 2006.
50. Grann V.R., Troxel A.B., Jacobson J.S., Zojwalla N., Hershman D., Glied S.A. and
Neugut, A.I.: Regional and racial disparities in breast cancer-specific and all-cause
mortality. Social Science and Medicine 62: 337-347, 2006.
51. Jacobson J.S., Grann V.R., Hershman D., Troxel A.B., Li H. and Neugut A.I.: Breast
biopsy and race/ethnicity among women without breast cancer. Cancer Detection and
Prevention 30: 129-133, 2006.
52. Ma G., Troxel A.B. and Heitjan D.F.: Author's reply. Statistics in Medicine 25:
3218-3220, 2006.
53. Neimann A.N., Shin D.B., Wang X., Margolis D.J., Troxel A.B. and Gelfand J.M.:
Prevalence of cardiovascular risk factors in patients with psoriasis. Journal of the
American Academy of Dermatology 55: 829-835, 2006.
54. Ochroch E.A., Troxel A.B. and Farrar J.T.: Women suffer more short and longterm
pain than men after major thoracotomy. Journal of Clinical Pain 22: 491-498, 2006.
15
55. Park J-H., Troxel A.B., Harvey R.G. and Penning T.M.: PAH o-quinones produced
by the Aldo-Keto-Reductases (AKRs) generate abasic sites, oxidized pyrimidines
and 8-oxo-dGuo via reactive oxygen species. Chemical Research in Toxicology 19:
719-728, 2006.
56. Parzen M., Lipstiz S.R., Fitzmaurice G.M., Ibrahim J.G. and Troxel A.: Pseudolikelihood methods for longitudinal binary data with non-ignorable missing
responses and covariates. Statistics in Medicine 25: 2784-2796, 2006.
57. Rebbeck T.R., Troxel A.B., Wan Y., Walker A.H., Panossian S., Gallagher S.,
Shatalova E.G, Blanchard R.M, Bunin G., DeMichele A., Rubin S.C., Baumgarten
M., Berlin M., Schinnar R., Berlin J.A. and Strom B.L.: Estrogen sulfation genes,
hormone replacement therapy, and endometrial cancer risk. Journal of the National
Cancer Institute 98: 1311-1120, 2006.
58. Shen Y-M., Troxel A.B., Vedantam S., Penning T.M. and Field J.: Comparison of
p53 mutations inducted by PAH o-quinones with those caused by antibenzo[a]pyrene diol epoxide in vitro: role of reactive oxygen and biological
selection. Chemical Research in Toxicology 19: 1441-1450, 2006.
59. Strom B.L, Schinnar R, Weber A.L, Bunin G.R., Berlin J.A., Baumgarten M.,
DeMichele A.M., Rubin S., Troxel A.B. and Rebbeck T.A.: Protective effect of
postmenopausal use of combined estrogen plus progestin hormone therapy on
endometrial cancer risk. American Journal of Epidemiology 165: 778-786, 2006.
60. Brauer J.A., Shin D.B, Troxel A.B., Shapiro M., Levy M. and Ming M.E.:
Characteristics of dermatologists who read dermatopathology slides. Journal of
Cutaneous Pathology 34: 687-692, 2007.
61. Clark L.N., Shin D.B., Troxel A.B., Khan S., Sober A.J. and Ming M.E.:
Association between the anatomic distribution of melanoma and sex. Journal of the
62. Gelfand J.M., Kurd S.K., Neimann A.L., Shin D.B., Margolis D.J. and Troxel, A.B.:
Psoriasis and the risk of myocardial infarction -‐ reply. Journal of the American
63. Gelfand J.M., Troxel A.B., Lewis J.D., Kurd S.K., Shin D.B., Wang X., Margolis
D.J. and Strom B.L: The risk of mortality in patients with psoriasis: Results from a
population-based study. Archives of Dermatology 143: 1493-1499, 2007.
64. Gorin S.S., Ashford A.R., Lantigua R., Desai M., Troxel A. and Gemson D.:
Implementing academic detailing for breast cancer screening in underserved
communities. Implementation Science 2: 43, 2007.
16
65. Klein R.Q., Teal V., Taylor L., Troxel A.B. and Werth V.P.: Number,
characteristics, and classification of patients with dermatomyositis seen by
dermatology and rheumatology departments at a large tertiary medical center.
Journal of the American Academy of Dermatology 57: 937-943, 2007.
66. Ochroch E.A., Troxel A.B., Frogel J.K. and Farrar J.T: The influence of race and
socioeconomic factors on patient acceptance of perioperative epidural analgesia
Anesthesia and Analgesia 105: 1787-1792, 2007.
67. Parzen M., Lipsitz S.R., Fitzmaurice G.M., Ibrahim J.G., Troxel A. and Molenberghs
G.: Pseudo-likelihood methods for the analysis of longitudinal binary data subject to
nonignorable non-monotone missingness. Journal of Data Science 5: 1-21, 2007.
68. Rebbeck T.R., Troxel A.B., Norman S., Bunin G.R., DeMichele A., Baumgarten M.,
Berlin M., Schinnar R. and Strom B.L: A retrospective case-control study of the use
of hormone-related supplements and association with breast cancer. International
Journal of Cancer 120: 1523-1528, 2007.
69. Rebbeck T.R., Troxel A.B., Norman S., Bunin G.R., DeMichele A., Schinnar R.,
Berlin J. and Strom B.: Pharmacogenetic modulation of combined hormone
replacement therapy by progesterone-metabolism genotypes in postmenopausal
breast cancer risk. American Journal of Epidemiology 166: 1392-1399, 2007.
70. Rebbeck T.R., Troxel A.B., Shatalova E.G., Blanchard R., Norman S., Bunin G.,
DeMichele A., Baumgarten M., Berlin M., Schinnar R., Berlin J.A. and Strom B.L.:
Lack of effect modification between estrogen metabolism genotypes and combined
hormone replacement therapy in post-menopausal breast cancer risk. Cancer
Epidemiology, Biomarkers, and Prevention 16: 1318-1320, 2007.
71. Rebbeck T.R., Troxel A.B., Walker A.H., Panossian S., Gallagher S., Shatalova
E.G., Blanchard R., Norman S., Bunin G., DeMichele A., Baumgarten M., Berlin M.,
Schinnar R., Berlin J.A. and Strom B.L: Pairwise combinations of estrogen
metabolism genotypes in post menopausal breast cancer etiology. Cancer
Epidemiology Biomarkers, and Prevention 16: 444-450, 2007.
72. Vahdat L.T., Cohen D.J., Zipin D., Lo K.S., Donovan D., Savage D., Tiersten A.,
Nichols G., Troxel A. and Hesdorffer C.S.: Randomized trial of low-dose
interleukin-2 vs cyclosporine A and interferon-gamma after high-dose chemotherapy
with peripheral blood progenitor support in women with high-risk primary breast
cancer. Bone Marrow Transplantation 40: 267-272, 2007.
73. Bonilla-Martinez Z.L., Albrecht J., Troxel A.B., Taylor L., Okawa J., Dulay S. and
Werth V.P.: The cutaneous lupus erythematosus disease area and severity index: a
responsive instrument to measure activity and damage in patients with cutaneous
lupus erythematosus. Archives of Dermatology 144: 173-180, 2008.
17
74. Cheville A.L., Troxel A.B., Basford J.R. and Kornblith A.B.: Prevalence and
treatment patterns of physical impairments in patients with metastatic breast cancer.
Journal of Clinical Oncology 26: 2621-29, 2008.
75. DeMichele A., Troxel A.B., Berlin J.A., Weber A.L., Bunin G.R., Turzo E.,
Schinnar R., Burgh D., Berlin M., Rubin S.C., Rebbeck T.R. and Strom B.L.: Impact
of raloxifene or tamoxifen use on endometrial cancer risk: a population-based casecontrol study. Journal of Clinical Oncology 26: 4151-4159, 2008.
76. Farrar J.T., Troxel A.B., Stott C., Duncombe P. and Jensen M.P.: Validity,
reliability, and clinical importance of change in a 0-10 numeric rating scale measure
of spasticity: a post hoc analysis of a randomized, double-blind, placebo-controlled
trial. Clinical Therapeutics 30: 974-985, 2008.
77. Gaines E., Bonilla-Martinez Z., Albrecht J., Taylor L., Okawa J., Troxel A.B. and
Werth V.P.: Quality of life and disease severity in a cutaneous lupus erythematosus
pilot study. Archives of Dermatology 144: 1062-2, 2008.
78. Gupta-Abramson V., Troxel A.B., Nellore A., Puttaswamy K., Redlinger M.,
Ransone K., Mandel S.J., Flaherty K.T., Loevner L.A., O'Dwyer P.J. and Brose
M.S.: Phase II trial of sorafenib in advanced thyroid cancer. Journal of Clinical
Oncology 26: 4714-4719, 2008.
79. Hormes J.M., Lytle L.A., Gross C.R., Ahmed R.L., Troxel A.B. and Schmitz K.H.:
The body image and relationships scale: development and validation of a measure of
body image in female breast cancer survivors. Journal of Clinical Oncology 26:
1269-1274, 2008.
80. Klein R.Q., Bangert C.A., Costner M., Connolly M.K., Tanikawa A., Okawa J., Rose
M., Fakharzadeh S.S., Fiorentino D., Lee L.A., Sontheimer R.D., Taylor L., Troxel
A.B. and Werth V.P.: Comparison of the reliability and validity of outcome
instruments for cutaneous dermatomyositis. British Journal of Dermatology 159:
887-894, 2008.
81. Krathan M., Dunham J., Gaines E., Junkins-Hopkins J., Kim E., Kolasinksi S.,
Kovarik C., Kwan-Morley J., Okawa J., Propert K., Rogers N., Rose M., Thomas P.,
Troxel A., Van Vorhees A., Von Feldt J., Weber A. and Werth V.: The cutaneous
lupus erythematosus disease activity and severity index (CLASI) expansion for
rheumatology and dermatology. Arthritis Care and Research 59: 338-344, 2008.
82. Kurd S.K., Smith N., VanVorhees A., Troxel A.B., Badmaev V., Seykora J.T. and
Gelfand J.M.: Oral curcumin in the treatment of moderate to severe psoriasis
vulgaris: a prospective clinical trial Journal of the American Academy of
Dermatology 58: 625-631, 2008.
18
83. Lewis J.D, Gelfand J.M., Troxel A.B., Forde K.A., Newcomb C., Kim H., Margolis
D.J. and Strom B.L.: Immunosuppressant medications and mortality in inflammatory
bowel disease. American Journal of Gastroenterology 103: 1428-1435, 2008.
84. Mirza N., Machtay M., Devine P.A., Troxel A., Abboud S.K. and Doty R.L.:
Gustatory impairment in patients undergoing head and neck irradiation.
Laryngoscope 118: 24-31, 2008.
85. Park J.-H., Gelhaus S., Vedantam S., Oliva A., Batra A., Blair I., Troxel A., Field J.
and Penning T.: The pattern of p53 mutations caused by PAH o-quinones is driven
by 8-oxo-dGuo formation while the spectrum of mutations is determined by
biological selection for dominance. Clinical Research in Toxicology 21: 1039-49,
2008.
86. Volpp K.G., John L.K., Troxel A.B., Norton L., Fassbender J. and Loewenstein G.:
Financial incentive-based approaches for weight loss: a randomized trial. Journal of
the American Medical Association 300: 2631-2637, 2008.
87. Volpp K.G., Loewenstein G., Troxel A.B., Doshi J., Price M., Laskin M. and
Kimmel S.E.: A test of financial incentives to improve warfarin adherence. BMC
Health Services Research 8: 272, 2008.
88. Yoon J.S., Newton S.M., Wysocka M., Troxel A.B., Hess S.D., Richardson S.K.,
Lin J.H., Benoit B.M., Kasprzycka M., Wasik N.A. and Rook A.H.: IL-21 enhances
antitumor responses without stimulating proliferation of malignant T cells of patients
with Sezary syndrome. Journal of Investigative Dermatology 128: 473-480, 2008.
89. Amaravadi R.K., Schuchter L.M., McDermott D.F., Kramer A., Giles L., Gramlich
K., Carberry M., Troxel A.B., Letrero R., Nathanson K.L., Atkins M.B., O'Dwyer
P.J. and Flaherty K.T.: Phase II trial of temozolomide and sorafenib in advanced
melanoma patients with or without brain metastases. Clinical Cancer Research 15:
7711-8, 2009.
90. Bacik P.R., Carton A.K., Zhang C., Troxel A.B. and Maidment A.D.: Breast percent
density: Estimation on digital mammograms and central tomosynthesis projections.
Radiology 252: 40-49, 2009.
91. Cheville A.L., Basford J.L, Troxel A.B. and Kornblith A.B.: Performance of
common clinician- and self-report measures in assessing the function of community
dwelling people with metastatic breast cancer. Archives of Physical Medicine and
Rehabilitation 90: 2116-24, 2009.
92. Elliott D.J., Zaoutis T.E., Troxel A.B., Loh A. and Keren R.: Empiric antimicrobial
therapy for pediatric skin and soft-tissue infections in the era of methicillin-resistant
Staphylococcus aureus. Pediatrics 123: 959-966, 2009.
19
93. Forde K.A., Reddy K.R., Troxel A.B., Sanders C.M. and Lee W.M.: Racial and
ethnic differences in presentation, etiology, and outcomes of acute liver failure in the
United States. Clinical Gastroenterology and Hepatology 7: 1121-26, 2009.
94. Gelfand J.M, Dommasch E.D., Shin D.B., Azfar R.S., Kurd S.K., Wang X. and
Troxel A.B.: The risk of stroke in patients with psoriasis. Journal of Investigative
Dermatology 129: 2411-18, 2009.
95. Kontos D., Bakic P.R., Carton A.K., Troxel A.B., Conant E.F. and Maidment A.D.:
Parenchymal texture analysis in digital breast tomosynthesis for breast cancer risk
estimation: A preliminary study. Academic Radiology 16: 283-98, 2009.
96. Nellore A., Paziana K., Ma C., Tsygankova O.M., Wang Y., Puttaswamy K., Iqbal
A.U., Franks S.R., Lv Y., Troxel A.B., Feldman M.D., Meinkoth J.L. and Brose
M.S.: Loss of Rap1GAP in papillary thyroid cancer. Molecular Endocrinology 23:
277, 2009.
97. Rebbeck T.R., DeMichele A., Tran T.V., Panossian S., Bunin G.R., Troxel A.B. and
Strom B.L.: Hormone-dependent effects of FGFR2 and MAP3K1 in breast cancer
susceptibility in a population-based sample of post-menopausal African-American
and European-American women. Carcinogenesis 30: 269-74, 2009.
98. Rosenbach M., Murrell D.F., Bystryn J.C., Dulay S., Dick S., Farkharzadeh S., Hall
R., Korman N.J., Lin J., Okawa J., Pandya A.G., Payne A.S., Rose M., Rubenstein
D., Woodley D., Vittorio C., Werth B.B., Williams E.A., Taylor L., Troxel A.B. and
Werth V.P.: Reliability and convergent validity of two outcome instruments for
pemphigus. Journal of Investigative Dermatology 129: 2404-10, 2009.
99. Ross A.S., Whalen F.M., Elenitsas R., Xu X., Troxel A.B. and Schmults C.D.:
Diameter of involved nerves predicts outcomes in cutaneous squamous cell
carcinoma with perineural invasion: An investigator-blinded retrospective cohort
study. Dermatologic Surgery 35: 1859-66, 2009.
100.Schmitz K.H., Ahmed R.L., Troxel A., Cheville A., Smith R., Lewis-Grant L.,
Bryan C.J., Williams-Smith C.T. and Greene Q.A.: A randomized trial of weight
lifting among women with breast cancer-related lymphedema. New England Journal
of Medicine 361: 664-73, 2009.
101. Schmitz K.H., Troxel A.B., Cheville A., Grant L.L., Bryan C.J., Gross C.R., Lytle
L.A. and Ahmed R.L.: Physical activity and lymphedema (the PAL trial): Assessing
the safety of progressive strength training in breast cancer survivors. Contemporary
Clinical Trials 30: 233-245, 2009.
20
102. Volpp K.G., Troxel A.B., Pauly M.V., Glick H.A., Puig A., Asch D.A., Galvin R.,
Zhu J., Wan F., DeGuzman J., Corbett E., Weiner J. and Audrain-McGovern J.: A
randomized, controlled trial of financial incentives for smoking cessation. New
England Journal of Medicine 360: 699-709, 2009.
103. Abramson V.G., Troxel A.B., Feldman M., Mies C., Wang Y., Sherman L.,
McNally S., Diehl A. and DeMichele A.: Cyclin D1b in human breast carcinoma
and coexpression with cyclin D1a is associated with poor outcome. Anticancer
Research 30: 1279-85, 2010.
104. Abuabara K., Azfar R.S., Shin D.B., Neimann A.L., Troxel A.B. and Gelfand J.M.:
Cause-specific mortality in patients with severe psoriasis: A population-based
cohort study in the United Kingdom. British Journal of Dermatology 163: 586-92,
2010.
105. Brauer J.A., Wriston C.C., Troxel A.B., Elenitsas R., Shin D.B., Guerry D. and
Ming M.E.: Characteristics associated with early and late melanoma metastases.
Cancer 116: 415-23, 2010.
106. Dommasch E., Shin D.B., Troxel A.B., Margolis D.J. and Gelfand J.M.: Reliability,
validity, and responsiveness to change of the Patient Report of Extent of Psoriasis
Involvement (PREPI) for measuring body surface area affected by psoriasis. British
Journal of Dermatology 162: 835-42, 2010.
107. Halbert C.H., Coyne J., Weathers B., Mahler B., Delmoor E., Vaughn D.,
Malkowicz S.B., Lee D. and Troxel A.B.: Racial differences in quality of life
following prostate cancer diagnosis. Urology 76: 559-64, 2010.
108. Halbert C.H., Kessler L., Troxel A.B., Stopfer J.E. and Domchek S.: Effect of
genetic counseling and testing for BRCA1 and BRCA2 mutations in African
American women: A randomized trial. Public Health Genomics 13: 440-8, 2010.
109. Hormes J.M., Bryan C., Lytle L.A., Gross C.R., Ahmed R.L., Troxel A.B. and
Schmitz K.H.: Impact of lymphedema and arm symptoms on quality of life in breast
cancer survivors. Lymphology 43: 1-13, 2010.
110. Kurd S.K., Gelfand J.M., Crits-Cristoph P. and Troxel A.B.: The risk of depression,
anxiety, and suicidality in patients with psoriasis: A population-based cohort study.
Archives of Dermatology 146: 891-5, 2010.
111. Mehta N.N., Azfar R.S., Shin D.B., Neimann A.L., Troxel A.B. and Gelfand J.M.:
Patients with severe psoriasis are at increased risk of cardiovascular mortality: A
cohort study using the General Practice Research Database. European Heart Journal
31: 1000-6, 2010.
21
112. Schmitz K.H., Ahmed R.L., Troxel A., Cheville A., Lewis-Grant L., Smith R.,
Bryan C.J., Williams-Smith C.T. and Chitthams J. Weight lifting for women at risk
for breast cancer-related lymphedema: a randomized trial. Journal of the American
113. Spiotta A.M., Stiefel M.F., Gracias V.H., Garuffe A.M., Kofke W.A., MaloneyWilensky E., Troxel A.B., Levine J.M. and Le Roux P.D.: Brain tissue oxygendirected management and outcome in patients with severe traumatic brain injury.
Journal of Neurosurgery 113: 571-80, 2010.
114. Thom S.R., Bhopale V.M., Milovanova T.M., Hardy K.R., Logue C.J., Lambert
D.S., Troxel A.B., Ballard K. and Eisinger D.: Plasma biomarkers in carbon
monoxide poisoning. Clinical Toxicology 48: 47-56, 2010.
115. Troxel A.B., Lipsitz S.R., Fitzmaurice G.M., Ibrahim J.G., Sinha D. and
Molenberghs G.A.: A weighted combination of pseudo-likelihood estimators for
longitudinal binary data subject to non-ignorable non-monotone missingness.
Statistics in Medicine 29: 1511-21, 2010.
116. Yassaee M., Fiorentino D., Okawa J., Taylor L., Coley C., Troxel A.B. and Werth
V.P.: Modification of the Cutaneous Dermatomyositis Disease Area and Severity
Index, an outcome instrument. British Journal of Dermatology 162: 669-73, 2010.
117. Dommasch E.D., Abuabara K., Shin D.B., Nguyen J., Troxel A.B. and Gelfand
J.M.: The risk of infection and malignancy with tumor necrosis factor antagomists
in adult patients with psoriatic disease: A systematic review and meta-analysis of
randomized controlled trials. Journal of the American Academy of Dermatology
64(6): 1035-50, 2011.
118. Evans K.G., Troxel A.B., DeNardo B.J., Introcaso C.E., Rook A.H. and Kim E.J. :
Validity assessment of the cutaneous T-cell lymphoma severity index to predict
prognosis in advanced mycosis fungoides/Sezary syndrome. Journal of the
American Academy of Dermatology 64(4): 682-9, 2011.
119. Halbert C.H., Barg F.K., Guerra C.E., Shea J.A., Armstrong K., Ferguson M.,
Weathers B., Coyne J. and Troxel A.B.: Cultural, economic, and psychological
predictors of colonoscopy in a national sample. Journal of General Internal
Medicine 26(11): 1311-6, 2011.
120. Halbert C.H., Stopfer J.E., McDonald J., Weathers B., Collier A., Troxel A.B. and
Domchek S. : Long-term reactions to genetic testing for BRCA1 and BRCA2
mutations: Does time heal women's concerns? Journal of Clinical Oncology 29:
4302-6, 2011.
22
121. John L.K., Loewenstein G., Troxel A.B., Norton L., Fassbender J.E. and Volpp
K.G.: Financial incentives for extended weight loss: A randomized, controlled trial.
Journal of General Internal Medicine 26(6): 621-6, 2011.
122. Klein R., Maghadam-Kia S., Lomonico J., Okawa J., Coley C., Taylor L., Troxel
A.B. and Werth V.P.: Development of the CLASI as a tool to measure disease
severity and responsiveness to therapy in cutaneous lupus erythematosus. Archives
of Dermatology 147(2): 203-8, 2011.
123. Kontos D., Ikejimba L.C., Bakic P.R., Troxel A.B., Conant E.F. and Maidment
A.D.A.: Analysis of parenchymal texture with digital breast tomosynthesis:
Comparison with digital mammography and implications for cancer risk assessment.
Radiology 26(1): 80-91, 2011.
124. Mehta N.N., Yu Y., Pinnelas R., Krishnamoorthy P., Shin D.B., Troxel A.B., and
Gelfand J.M.: Attributable risk estimate of severe psoriasis on major cardiovascular
events. American Journal of Medicine 124(8): 775.e1-6, 2011.
125. Seminara N.S., Abuabara K., Shin D.B., Langan S.M., Kimmel S.E., Margolis D.,
Troxel A.B., and Gelfand J.M.: Validity of the health improvement network (THIN)
for the study of psoriasis. British Journal of Dermatology 164(3): 602-9, 2011.
126. Sinha S.K., Troxel A.B., Lipsitz S.R., Sinha D., Fitzmaurice G.M., Molenberghs
G., Ibrahim J.G.: A bivariate pseudo-likelihood for incomplete longitudinal binary
data with nonignorable non-monotone missingness. Biometrics 67(3): 1119-26,
2011.
127. Wysocka M., Dawany N., Benoit B., Kossenkov A.V., Troxel A.B., Gelfand J.M.,
Sell M.K., Showe L.C. and Rook A.H. : Synergistic enhancement of cellular
immune responses by the novel Toll receptor 7/8 agonist 3M-007 and interferongamma: implications for therapy of cutaneous T-cell lymphoma. Leukemia &
Lymphoma 52(10): 1970-9, 2011.
128. Abuabara K., Wan J, Troxel A.B., Shin D.B., Van Voorhees A.S., Bebo B.F.,
Krueger G.G., Callis Duffin K., and Gelfand J.M.: Variation in dermatologist beliefs
about the safety and effectiveness of treatments for moderate-to-severe psoriasis.
Journal of the American Academy of Dermatology 2012, In press.
129. Azfar R.S., Seminara N.M., Shin D.B., Troxel A.B., Margolis D.J., Gelfand J.M.:
Increased risk of diabetes mellitus and likelihood of receiving diabetes mellitus
treatment in patients with psoriasis. Archives of Dermatology, 148:995-1000, 2012.
23
130. Brown J.C., Troxel A.B. and Schmitz K.H.: Safety of weightlifting among women
with or at risk for breast cancer-related lymphedema: Musculoskeletal injuries and
health care use in a weightlifting rehabilitation trial. The Oncologist, 17:1120-8,
2012.
131. Forde K.A., Haynes K., Troxel A.B., Trooskin S., Osterman M.T., Kimmel S.E.,
Lewis J.F. and Lo Re V.: Risk of myocardial infarction associated with chronic
hepatitis C virus infection: A population-based cohort study. Journal of Viral
Hepatitis, 19, 2012.
132. Gelfand J.M., Wan J., Callis Duffin K., Krueger G.G., Kalb R.E., Weisman J.D.,
Sperber B.R., Stierstorfer M.B., Brod B.A., Schleicher S.M., Bebo B.F. Jr, Troxel
A.B., Shin D.B., Steinemann J.M., Goldfarb J., Yeung H. and Van Voorhees A.S.:
Comparative effectiveness of commonly used systemic treatments or phototherapy
for moderate to severe plaque psoriasis in the clinical practice setting. Archives of
Dermatology 148(4): 487-94, 2012.
133. Kimmel S.E. and Troxel A.B.: Novel incentive-based approaches to adherence.
Journal of the Society for Clinical Trials 2012, In press.
134. Kimmel S.E., Troxel A.B., Loewenstein G., Brensinger C.M., Jaskowiak J., Doshi
J.A., Laskin M. and Volpp K.: Randomized trial of lottery-based incentives to
improve warfarin adherence. American Heart Journal 164(2): 268-74, 2012.
135. Langan S.M., Seminara N.M., Shin D.B., Troxel A., Kimmel S.E., Mehta N.N.,
Margolis D.J. and Gelfand J.M.: Prevalence of metabolic syndrome in patients with
psoriasis: A population-based study in the United Kingdom. Journal of Investigative
Dermatology 132: 556-62, 2012.
136. Liao K., Freres D. and Troxel A.B.: A transition model for quality of life data with
non-ignorable non-monotone missing data Statistics in Medicine 2012, In press.
137. McDonald J.A., Barg F., Weathers B., Guerra C., Troxel A.B., Domchek S., Bowen
D., Shea J. and Halbert C.H.: Understanding African American participation in
cancer genetics research. Journal of the National Medical Association 2012, In
press.
138. McDonald J.A., Weathers B., Barg F.K., Troxel A.B., Shea J.A., Bowen D., Guerra
C.E. and Halbert C.H.: Donation intentions for cancer genetics research among
African Americans. Genetic Testing and Molecular Biomarkers 16: 252-8, 2012.
139. Mehta N.N., Krishnamoorthy P., Yu Y., Khan O., Raper A., Van Voorhees A.,
Troxel A.B. and Gelfand J.M.: The impact of psoriasis on 10-year Framingham
risk. Journal of the American Academy of Dermatology 67: 796-8, 2012.
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25
140. Speck R.M., Sammel M.D., Troxel A.B., Cappola A.R., Williams-Smith C.T.,
Chittams J., Scott P., Tuton L.W.and Abbuhl S.B.: Factors impacting the departure
rate of female and male junior medical school faculty: Evidence from a longitudinal
analysis. Journal of Women's Health 21(10): 1059-65, 2012
141. Troxel, A.B., Volpp, K.G.: Effectiveness of financial incentives for longer-term
smoking cessation: Evidence of absence or absence of evidence? American Journal
of Health Promotion 26(4): 204-7, 2012.
142. Wan J., Abuabara K., Shin D.B., Troxel A.B., Bebo B.F. and Gelfand J.M.:
Dermatologist response rates to a mailed questionnaire: a randomized trial of
monetary incentives. Journal of the American Academy of Dermatology 66(1): e1820, 2012.
143. Wan J., Abuabara K., Troxel A.B., Shin D.B., Van Vorhees A.S., Bebo B.F.,
Kruger G.G., Duffin K.C. and Gelfand J.M.: Dermatologist preferences for first-line
therapy of moderate to severe psoriasis in healthy adult patients. Journal of the
144. Wan J., Abuabara, K., Troxel A.B., Shin D.B., Van Voorhees A.S., Bebo B.F. Jr.,
Kruger G.G., Duffin K.C., and Gelfand J.M.: Dermatologist preferences for
treatments to compare in future randomized controlled comparative effectiveness
trials for moderate to severe psoriasis. Archives of Dermatology 148(4): 539-41.
2012.
145. Yeung H., Wan J., Van Voorhees A.S., Callis-Duffin K., Krueger G.G., Kalb R.E.,
Weisman J.D., Sperber B.R., Brod B.A., Bebo F., Schleicher S.M., Shin D.B.,
Troxel A.B. and Gelfand J.M. : Patient-reported reasons for the discontinuation of
commonly used treatments for moderate-to-severe psoriasis. Journal of the
American Academy of Dermatology 2012, In press.
Research Publications: peer-reviewed reviews:
None
Contributions to peer-reviewed clinical research publications, participation cited but not by
authorship:
None
Research publications, non-peer reviewed:
1. Troxel, A.B. and Blumenstein, B. Time to event (TTE) methods as a way of analyzing
quality of life (QOL) and/or symptom data. American Statistical Association, Proceedings of
the Biopharmaceutical Section 73-8, 1997.
Abstracts: (past three years only)
1. Abuabara K., Azfar R.S., Shin D.B., Neimann A.L., Troxel A.B. and Gelfand J.M.:
Cause-specific mortality in patients with severe psoriasis: A cohort study using the
general practice research database. (oral presentation). Society of Investigative
Dermatology 2009.
2. Azfar R.S., Neimann A.L., Shin D.B., Troxel A.B. and Gelfand J.M.: Risk of
cardiovascular mortality in patients with severe psoriasis. (poster presentation). Society
for Investigative Dermatology 2009.
3. Brose M.S., Troxel A.B., Redlinger M., Harklacker K., Redlinger C., Chalian A.A.,
Flaherty K.T., Loevner L.A., Mandel S.J. and O'Dwyer P.J.: Effect of BRAF v600E on
response to sorafenib in advanced thyroid cancer patients. (poster presentation).
American Society of Clinical Oncology 2009.
4. Cetnar J.P., Rosen M.A., Vaughn D.J., Haas N.B., Troxel A.B., Song H., Adluru G.,
Flaherty K.T., O'Dwyer P.J. and Amaravadi R.K.: Phase II study of sorafenib and
docetaxel in men with metastatic castration resistant prostate cancer (mCRPC). (poster
presentation). American Society of Clinical Oncology 2009.
5. Cheville A.L., Basford J., Troxel A.B. and Kornblith A.: Determinants of functional
disability in stage IV breast cancer. (poster presentation). Society of Clinical Oncology
2009.
6. Dommasch E., Shin D., Troxel A.B., Margolis D.J., Chren M.M. and Gelfand J.M.:
Reliability and validity of the Patient Report of Extent of Psoriasis Involvement
(PREPI) for determining psoriasis severity. (poster presentation). Society for
Investigative Dermatology 2009.
7. Kurd S.K., Troxel A.B. and Gelfand J.M.: The risk of depression in patients with
psoriasis. (poster presentation). International Society for Pharmacoepidemiology 2009.
8. Mehta N.N., Azfar R.S., Shin D.B., Neimann A.L., Troxel A.B. and Gelfand J.M.:
Patients with severe psoriasis and no history of cardiovascular disease are at increased
risk of cardiovascular mortality. (poster presentation). American Heart Association
2009.
9. Seminara N., Abuabara K., Shin D., Kimmel S., Margolis D.J., Troxel A.B. and
Gelfand J.M.: Prevalence of psoriasis severity and predictive value of psoriasis codes
in The Health Improvement Network (THIN)-‐ a population based study. (oral
presentation). Society of Investigative Dermatology 2009.
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10. Wriston C.C., Troxel A.B., Shin D.B., Schaffer A., Rubin A.I., Brauer J.A. and
Ming M.E.: Tumor infiltrating lymphocytes are a prognostic marker for survival in
patients who develop melanoma metastases. (poster presentation). Society of
11. Baek S., Bellamy S.L., Troxel A.B., Ten Have T.R. and Jemmott J.B.: Extension of
Max-ID copula to longitudinal binary couples' data. (oral presentation). Joint
Statistical Meetings 2010.
12. Baek S., Bellamy S.L., Troxel A.B., TenHave T.R. and Jemmott J.B.: A coupla
approach for estimating correlation of shared couple behaviors. (poster presentation).
ENAR Annual Meeting 2010.
13. Brose M.S., Troxel A.B. and Mamtani R.: Phase II trial of everolimus + sorafenib
for patients with differentiated thyroid cancer (DTC) who progress on sorafenib alone.
(oral presentation). ASCO Annual Meeting 2010.
14. De Blank P.M.K., Zaoutis T., Fisher B., Troxel A.B., Kim J. and Aplenc R.: Risk
factors for clostridium difficile infection in children with malignancy (oral
presentation). ASCO Annual Meeting 2011.
15. Keefe S.M., Troxel A.B., Rhee S., Puttaswamy K., O'Dwyer P.J., Loevner L.A.,
Mandel S.J. and Brose M.S.: Phase II trial of sorafenib in patients with advanced
thyroid cancer. (oral presentation). ASCO Annual Meeting 2011.
16. Langan S., Seminara N.M., Troxel A.B., Shin D.B., Margolis, D.J., Kimmel S.,
Mehta N.N. and Gelfand, J.M. : Prevalence of metabolic syndrome in patients with
psoriasis: A population-based study in the United Kingdom. (oral presentation).
Society of Investigative Dermatology 2011.
17. Seminara N.M, Azfar R.S., Shin D.B., Troxel A.B., Margolis D.J. and Gelfand J.M.:
Patients with psoriasis are at increased risk of diabetes: A population based study. (oral
presentation). Society of Investigative Dermatology 2011.
18. Wan J., Abuabara K., Troxel A.B., Shin D.B., Van Voorhees A.S., Bebo B.F. Jr.,
Krueger G.G., Callis Duffin K. and Gelfand J.M.: Dermatologist preferences for firstline therapy of moderate-to-severe psoriasis in healthy adults. (poster presentation).
Society of Investigative Dermatology 2011.
19. Yu Y., Mehta N.N., Male S., Krishnamoorthy P., Haynes K., Seminara N., Shin D.,
Troxel A.B., Sanford Schwartz J. and Gelfand J.M.: The risk of myocardial infarction
in patients with psoriasis: results from a large population-based cohort study. (oral
presentation). American Heart Association Scientific Sessions 2011.
27
20. Abuabara K., Wan J., Troxel A.B., Shin D.B., Van Vorhees A.S., Bebo B.F.,
Krueger G.G., Duffin K.C. and Gelfand J.M. : Variation in dermatologist beliefs about
the safety and effectiveness of psoriasis treatments (oral presentation). Society of
21. Brown J., Schmitz K. and Troxel A.B.: Musculoskeletal injuries in weight lifting
among women with or at-risk for breast-cancer-related lymphedema. (poster
presentation). Society of Behavioral Medicine 2012.
22. Brown J.C., Troxel A.B. and Schmitz K. : Musculoskeletal injuries and healthcare
needs among women with or at-risk for lymphedema in a weight lifting exercise trial
(oral presentation). American College of Sports Medicine 2012.
23. Kimmel S.R., Troxel A.B., Brensinger C., French B., Liu Q., Lowenstein G. and
Volpp K.G. : A randomized trial of interventions to improve warfarin adherence
(poster presentation). Institute on Aging Annual Retreat, University of Pennsylvania
2012.
24. Ogdie A., Haynes K., Troxel A.B, Love T., Hennessy S., Choi H. and Gelfand J. :
Mortality in patients with psoriatic arthritis compared to patients with rheumatoid
arthritis, psoriasis alone, and the general population. American College of
Rheumatology conference 2012.
25. Ranganathan A., Schwed-Lustgarten D., Aggarwal C., Werner L., Torigian D.A.,
Troxel A.B., Evans T.L., Stevenson J., Cohen R.B., Vaidya B., Rao C., Connelly
M.C., Albelda S. and Langer C.J. : Circulating tumor cells (CTCs) in patients with
small cell lung cancer (SCLC): A marker of disease burden, therapeutic response, and
predictor of disease relapse (oral presentation). ASCO 2012.
26. Troxel A.B. and Volpp K.G.: Effectiveness of financial incentives for longer-term
smoking cessation (poster presentation). Institute on Aging Annual Retreat, University
of Pennsylvania 2012.
27. Yeung H., Duffin C.K., Wan J., Troxel A.B., Shin D. and Gelfand J.M. : Patientreported reasons for discontinuation of commonly used treatments for moderate to
severe psoriasis. (oral presentation). Society of Investigative Dermatology 2012.
28. Troxel A.B.: Mortality in Patients with Psoriatic Arthritis Compared to Patients with
Rheumatoid Arthritis, Psoriasis Alone, and the General Population (oral presentation).
ACR/ARHP Annual Meeting 2012.
Editorials, Reviews, Book Chapters, Including Participation in Committee Reports (print or
other media:
1. Troxel A.B. and Moinpour C.M. Statistical analysis of quality of life data. In Handbook of
Statistics in Clinical Oncology, J. Crowley, ed. New York: Marcel Dekker, Inc., 2001.
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2. Troxel A.B. and Moinpour C.M. Design and analysis of quality of life data. In Handbook of
Statistics in Clinical Oncology, 2nd ed., J. Crowley and D. Ankerst, eds. Boca Raton: CRC
Press, Inc. 2005.
3. Troxel A.B. A review of Missing Data in Clinical Studies, by G. Molenberghs and M. G.
Kenward. Journal of Biopharmaceutical Statistics, 18: 588-9, 2008.
4. Troxel A.B. and Moinpour C.M. Design and analysis of quality of life data. In Handbook of
Statistics in Clinical Oncology, 3rd ed., J. Crowley and A Hoering, eds. Boca Raton: CRC
Press, Inc. 2012.
Books:
None
Alternative Media:
None
Patents:
None

UNIVERSITY OF PENNSYLVANIA PERELMAN SCHOOL OF MEDICINE Curriculum Vitae

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