Golden Herbs used in Piles Treatment: A Concise Report Rajani Chauhan
Transcription
Golden Herbs used in Piles Treatment: A Concise Report Rajani Chauhan
International Journal of Drug Development & Research | October-December 2012 | Vol. 4 | Issue 4 | ISSN 0975-9344 | Available online http://www.ijddr.in Covered in Official Product of Elsevier, The Netherlands SJR Impact Value 0.03 & H index 2 ©2012 IJDDR Golden Herbs used in Piles Treatment: A Concise Report Rajani Chauhan2, Km. Ruby1*, Jaya Dwivedi1 1 Department of Chemistry, Banasthali University, Tonk, Rajasthan, 304022, India. Department of Pharmacy, Banasthali University, Tonk, Rajasthan, 304022, India 2 Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 Abstract Copyright © 2012 IJDDR, Km. Herbal medicine is also called phytomedicine. It is is an open access paper distributed under the refers to using a plant's seeds, berries, roots, copyright agreement with Serials Publication, which leaves, disease permits golden reproduction in any medium, provided the original bark, or treatment.Herbs flowers have for many phytochemicals or secondary metabolites to treat unrestricted use, Ruby et al. This distribution, and work is properly cited. disease. They have a long tradition of use outside of conventional medicine. Hemorrhoids or Piles Article History:------------------------ treatment through Herbs has been effective and a Date of Submission: 08-10-2012 golden treatment without any side-effects. There Date of Acceptance: 09-11-2012 are some herbs which is useful in piles treatment Conflict of Interest: NIL such as Aesculus hippocastanum, Allium cepa, Source of Support: NONE Bergenia ligulata, Bergenia ciliata, Bergenia stracheyi, Hamamelis aculeatus, Terminalia virginiana chebula Ruscus Vaccinium myrtillus, Verbascum thapus etc. INTRODUCTION Piles or a hemorrhoid is a varicose and often inflamed condition of the veins, inside or just outside the rectum or hemorrhoids are swollen dilated or bulging inflamed veins that develop in the lower *Corresponding author, Mailing address: Km. Ruby E-Mail: [email protected] rectum caused by increased pressure in the rectal veins. There are two types of hemorrhoids external hemorrhoids and internal hemorrhoids. There are many natural treatments for hemorrhoids or piles, Key words: herbs are one of them. 1, 2 Herbs, Golden treatment, Piles, Phytomedicine Phytochemicals Golden herb used in Piles treatment 1. Aesculus hippocastanum How to Cite this Paper: Rajani Chauhan2, Km. Ruby1*, Jaya Dwivedi1 “Golden Herbs used in Piles Treatment: A Concise Report” Int. J. Drug Dev. & Res., October-December 2012, 4(4): 50-68 PREFACE Aesculus hippocastanum is commonly known as horse chestnut. It is large deciduous, rapidly-growing trees have height of 36 meters. It is native to the Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier 50 Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 countries of the Balkan Peninsula, but because of its 2. Allium cepa large, showy flower clusters the tree is cultivated PREFACE worldwide for its beauty. Flowers are white or pink The Allium cepa resembles the greens of a leek and with a small red spot. Leaves are large, consisting of produces soft, white flowers. The onion itself grows either five or seven leaflets and the fruit is round as a bulb under the soil with the plant's roots with a thick, green, spiny husk containing a glossy extending from its base. Allium cepa is an evergreen brown seed (chestnut or conker). While the common Bulb name for the tree is horse chestnut, it is also known hermaphrodite (have both male and female organs) as buckeye, and like other buckeyes, is a member of and are pollinated by Bees, insects. The plant prefers the Hippocastanaceae family, rather than the light (sandy) and medium (loamy) soils and requires chestnut horse well-drained soil. The plant prefers acid, neutral and chestnut, is believed to be derived from the brown basic (alkaline) soils. and can grow in very alkaline conkers that look similar to chestnuts and because a soils. It cannot grow in the shade. It requires moist horseshoe shaped with spots soil. Bulb - raw or cooked. A very versatile food, the resembling horseshoe nails) is left on the twig when bulb can be 10cm or more in diameter and is widely autumn.3-5 used in most countries of the world. Eaten raw, it can family (Castanea). the leaves drop off in mark The name, (complete growing to 0.6 m. The flowers are be sliced up and used in salads, sandwich fillings etc, it can be baked or boiled as a vegetable in its own right and is also commonly used as a flavouring in soups, stews and many other cooked dishes. Some cultivars have been selected for their smaller and often hotter bulbs and these are used for making Fig 1: Aesculus hippocastanum pickles. Leaves - raw or cooked. There are some Secondary metabolites cultivars, the spring onions, that have been selected Aaescin, Quercetin, Kaempferol, Proanthocyanidin, for their leaves and are used in salads whilst still Coumarins, Fraxin and Aesculin.5-8 young and actively growing - the bulb is much smaller than in other cultivars and is usually eaten Therapeutic use in piles with the leaves. By successional sowing, they can be Piles can also be healed completely using horse available at any time of the year. The flowers are chestnut which is found to be one of the excellent somewhat dry and are less pleasant than many other herbal cures for the problem of same. The extract of species.12 this particular herb is found to contain an excellent The seeds are sprouted and eaten. They have a enzyme, namely aescin is known to show anti delicious onion, flavour.12 inflammatory properties which can be used in curing the problem of piles. Taking small quantity of horse chestnut extract can be beneficial in keeping the vein walls healthier and hence preventing the problem of piles. Being a toxic herb, it should not be consumed in large quantities.9-11 Fig 2: Allium cepa 51 Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report Secondary metabolites glutamyl-L-valine (+)L-S-Prop-1-enyl-cysteine-s-oxide.,1(F)-beta- carboxy-N-propyl)cysteine Gamma-L-glutamyl-S-(2- fructosyl-sucrose ., 2-Methyl-but-2-en-1-al Methyl-butyr-2-aldehyde zymostenol .,2- .,Gamma-L-glutamyl-S-(2- carboxy-propyl)-L-cysteinyl glycine ethyl ester 4-Alpha-methyl- .,Gamma-L-glutamyl-S-propenyl cysteine sulfoxide .,4-S-Oxide(trans)dec-2-ene,5-ethyl- .,Glucofructan (Allium cepa) .,Glucose .,Glutamic Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 4,6,7-Trithia (diastereomer) .,4-S-Oxide(trans)dec-2- acid ene,5-ethyl-4,6,7-trithia .,4-S-Oxide(trans/cis)deca- .,Gramisterol .,Iso-quercitrin 2,8-diene,5-ethyl-4,6,7-thithia(diastereomer).,4- beta-D-glucoside SOxide (trans/ trans)deca-2,8-diene,5-ethyl-4,6,7- .,Kaempferol-3,4’-di-O-beta-D-glucoside thithia(diastereomer).,4-S .,Kaempferol-4’,7-di-O-beta-D-glucoside Oxide(trans/trans)deca- .,Glutathione .,Glycine .,Iso-rhamnetin .,Kaempferol-4’-0-beta-D-glucoside sucrose2,3-Dimethylbicyclo(2,2,1)hexan cysteine sulfoxide acid Iso-rhamnetin 4’-O- 2,8-diene,5-ethyl-4,6,7-thithia.,6(G)-Beta-fructosyle-5-oxide- .,Glycolic .,Kaempferol .,L-2-Propenyl- .,L-Gamma-glutamyl- 5,6-dithia(1,2,3,4-alpha-5-beta).,2,3-Dimethyl- phenylalanine thiophene.,2,4-Dimethylthioph phenylalanine .,Gamma-L-glutamyl-L-arginine .,L- ene.,24- ethyl ester .,L-Gamma-glutamyl- Methylenecycloartanol28-Iso-fucosterol.,31-Nor- Methyl-cysteine sulfoxide .,Lophenol .,Leutein.,Malic cycloartenol.,31-Nor-lanoste acid .,Melatonin.,Methionine methylsulfonium salt nol.,9,10,13- Trihydroxy-octadec-11-enoicacid.,9,12,13Trihydroxy-octadec-10-enoic acid .,Methionine .,Abscisic acid sulfone .,Methionine (methyl-sulfinyl).,propyl-disulfide .,Methyl, 1- .,Mevalonic Acetal .,Acetic acid .,Adenosine .,Allicin .,Alliin acid.,N-Propyl gamma-glutamyl-peptide cepa .,Oleanolic acid .,Oleic acid: .,Onion coat colorant polysaccharide .,Allyl-propyl-disulfide .,Alpha amyrin .,Oxalic acid .,Palmitic acid .,Para-coumaric acid .,Alpha linolenic acid .,Para-hydroxybenzoic .,Ascorbic acid .,Alliin Allium Alpha-sitosterol .,Arabinose .,Benzyl-iso-thiocyanate .,Beta mercaptan monoglycoside .,Nonadecanoic acid acid .,Pelargonidin Phloroglucinol carboxylic carotene Beta-sitosterol .,Butane-cis-1-cis-4-dithial- acid.,Phloroglucinol.,Prop-cis-enyl-disulfide S-S-dioxide,2,3-dimethyl.,Caffeic (trans)-enyl propyl-trisulfide .,Propan-1-ol .,Propane- oxalate .,Catechol .,Cepaene acid 1 .,Calcium .,Cepaene 2-A .,Prop- 1-thiol .,Propional .,Propionaldehyde .,Prostaglandin .,Cepaene 2-B .,Cepaene 3 .,Cepaene 4-A .,Cepaene 4- A B .,Prostaglandin E-1 .,Prostaglandin F .,Protocatechuic .,Cholest-7-en-3-beta-ol.,Cholesterol .,Choline .,Prostaglandin A-1 .,Prostaglandin .,Cis-Propanethial-s-oxide .,Cis-zweibelane .,Citric acid:.,Pyrocatechol acid.,Cyanidin Quercetin-3,4’-di-O-Beta-D-glucoside.,Quercetin- .,Cyanidin bioside .,Cyanidin monoglycoside diglycoside .,Pyruvic B acid.,Quercetin: .,Cyanidin-3-O- 4’,7-di-O-Beta-D-glucoside.,Quercetin -4-di-O-Beta- laminariobioside .,Cyclo-(2,1,1)-heptane-5-oxide,cis- Dglucoside .,Raffinose .,Rhamnose .,Ribose .,Rutin 2,3-dimethyl-5,6-dithia.,Cyclo-(2,1,1)-heptane-5- .,S-(2-Carboxy-propyl) glutathione.,S-(beta-carboxy- oxide,trans-2,3-dimethyl-5,6- beta-methyl-L-ethyl)cysteine .,S-1-cis-propenyl ester dithia.,Cycloalliin.,Cycloartanol., methyl sulfinothioic acid .,S-1-Cis-propenyl ester Cycloartenol.,Cycloeucalenol .,Cysteine Di-n-propyl- propyl sulfinothioic acid S-1-Propenyl ester n-propyl disulfide .,Dimethyl-trisulfide .,Diphenylamine ., sulfinothioic acid(cis) .,S-1-Propenyl ester n-propyl Ferulic acid., Fructose .,Gamma-gultamyl leucine sulfinothioic acid(trans) .,S-1-Trans-propenyl ester .,Gamma-glutamyl-S-(Beta-carboxy-Beta-methyl- methyl sulfinothioic acid .,S-1-Trans-propenyl ester ethyl)-cysteinyl glycine .,Gamma-L-glutamyl cysteine propyl sulfinothioic acid.,S-Allyl-cysteine.,S-Methyl- .,Gamma-L-glutamyl-L-iso-leucine cysteine sulfoxide Gamma-L- S-N-Propyl ester N-propyl Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier 52 Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report sulphinothioic sulfinothioic acid acid .,S-Propyl ester S-Propyl-cysteine propyl sulfoxide .,Satiomem .,Sinapic acid .,Sodium prop-(cis)-1-enylthiosulfate .,Sodium prop-(trans)-1-enyl-thiosulfate .,Sodium propyl-thiosulfate .,Spiraeoside.,Stearic acid.,Stigmasterol .,Succinic acid .,Sucrose .,Sugars Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 .,Thiopropanal-S-oxide Fig. 3: Bergenia ciliate .,Thiopropional-S-oxide Secondary metabolites .,Valine .,Xylitol .,Xylose .,Zeaxanthin 13 Tannic acid, Gallic acid, Glucose, Mucilage, Wax, Therapeutic use in piles Metarbin, Albumen, Mineral Salts, Bergenin, (+)- Onions are valuable in bleeding piles. About thirty Catechin, Gallicin. 14-16 grams of this vegetable should be finely rubbed in water and sixty grams of sugar added to it. It should Therapeutic use in piles be taken twice daily by the Patient. Onion is also Bergenia ciliata used in piles treatment in the form useful in the treatment of dry piles. A crushed onion, of tinctures and powder. 14-16 skinned and roasted in aches, may be applied with 4. Bergenia ligulata beneficial results.9-13 PREFACE 3. Bergenia ciliata Bergenia ligulata syn. Saxifraga ligulata is being PREFACE widely accepted under this name. the use of various Bergenia ciliata is the source of Pashanbheda after names attributed to it, viz., Pashanbheda, Pashana, Bergenia ligulata. Bergenia ciliata leaves are Zakhmehayat, suborbicular or broadly obovate, rounded at base and Ashmabhed, Nagabhid, Upalbhedak, Parwatbhed apex, margin finely denticulate and densely ciliata, and Shilabhed (dissolving or piercing stones or slabs) leaves otherwise glaborous. Flowers green, lobes etc. It belongs to family saxifragaceae. Its medicinally acute, denticulate near apex; petals obovate, white used part is rhizome. The plant Bergenia ligulata is tinged pink. Flowering time of Bergenia ciliata is chief botanical source of pashanbheda drug used in February to April and fruiting time is March to indigenous system of medicine and incorporated in July.It is found in Afghanistan, South Tibet, Bhutan medical texts and material media. It is a perennial, (Phuntsoling district, Deothang district, Ha district climbing plant that grows well in moist and shady and Mongar district. in areas, especially in the foothills of the Himalayas and Himalayas (Kumaon), Meghalaya, Lushai hills West the Khasi hills Assam. The stems show thick, ovate Bengal and bright red leaves seasonally. The flowers are (Darjeeling, In India it is found Labha, Takdah, Rimbick( Kalimpong), Arunachal Pradesh (Nyam Jang Chu), Kyongnosla, Changu, Karponanag, Lachen Asmaribheda, white, pink or purple.14, 16, 17 to Thongu, Nathang, Prekchu-Tsokha, PangolakhaSubaney Dara, Gangtok (domesticated) in sikkim.14-16 Fig.4: Bergenia ligulata 53 Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier Ashmabhid, Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report Secondary metabolites PREFACE Bergenin, Catechin Brassica rapa commonly known as turnip is one of Gallic acid, Starch, Minerals, Vitamins, Albumin, the most commonly grown and widely adapted root Glucose, Mucilage, Coumarin, Tannic acid, Steroids, crops, as general farm crop, truck crop, or home- Flavonoids, Glycosides, garden crop. Roots eaten raw or cooked as a β-Sitosterol, vegetable, and tops as potherb like spinach. Roots Paashaanolactone, Arbutin, Terpenoids, Carbohydrates and Tannins, Saponins , Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 Stigmesterol. 14, 16, 17 also grown for feeding to livestock during fall and winter. Biennial herb with swollen tuberous white- Therapeutic use in piles fleshed taproot, lacking a neck; leaves light to Bergenia ligulata root, rhizome and leaf powder and extract in water is used by local tribes. 14, 16, 17 medium green, hairy or bristly, stalked, lyratepinnatifid, 30–50 cm long, stem-leaves sometimes glaucous with clasping base; flowers bright yellow, 5. Bergenia stracheyi sepals spreading: petals 6–10 mm long, those in PREFECE anthesis close together and commonly overtopping Bergenia stracheyi (HK.) is a rhizometic herb species the unopened buds; outer 2 stamens curved found in Afghanistan to Uttarakhand, between 3300- outwards at base and much shorter than inner 4500 m in alpine slopes. W. Himalayas from 2700- stamens; fruit 4–6.5 cm long, with long tapering 4700 m, Afghanistan, Tadzhikistan. Commonly beak, on divaricate-ascending pedicels 3.2–6.5 cm growing on moist rocky slopes in Kashmir, Baltistan, long; seeds blackish or reddish-brown, 1.5–2 mm in Gilgit, Chitral and Upper Kaghan areas on much diameter. Fl. and fr. second spring. Cultivated in higher and colder altitudes. The plant, rather small in Europe for over 4000 years, probably native to stature, is very attractive in autumn when the leaf central and southern Europe, now spread throughout colour changes to red.14,16,18 Fig. 5: Bergenia stracheyi Secondary metabolites Free anthraquinone, Ascorbic acid, Carbohydrates, Phenolics, Saponins, Steroids, Bergecins A, Bergecins B, Bergenin. 14,16,18 Therapeutic use in piles Bergenia stracheyi used in piles as a form of powder and tincture by the local tribes of Pithoragarh. 14,16,18 world, including most parts of the tropics.19 Fig 6: Brassica rapa Secondary metabolites Protein, Fat, Total carbohydrate, Fiber, Ash, Ca, Fe, Na, K, Thiamine, Riboflavin, Niacin, Ascorbic acid , Erucic, Linoleic, and Linolenic acids.20,21 Therapeutic use in piles The leaves of turnip have been found useful in this disease. The juice of these leaves should be extracted and 150 ml given to the patient. It is, however, 6. Brassica rapa necessary to take a proper diet of raw fruits and Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier 54 Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report vegetables while taking this juice. For better results, setosterols, 50 ml of the juice should be mixed with equal Hentriacontanol, , Stigmasterol, Euphorbol and its quantities of juices of watercress, spinach, and Hexacosanate, Iingenol Taraxerone, Bergaptene, carrots. Stigmasterol, 9-13 Xanthotoxol, Sitosterol Campesterol, Tyrosine. Ficusin, Taraxasterol, Rutin, Sapogenin, Calotropenyl acetate, Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 7. Ficus carica Lepeolacetate, PREFACE Albumin, Ficus constituted one of the largest genera of Proteolytic enzymes, Diastase, Esterase, Lipase, medicinal plants with about 750 species of woody Catalase, Peroxidase. 33-36 Oleanolic Cerin, Sugar, Caoutchouc, Malic acid, Resin, Rennin, plants, trees, and shrubs primarily occurring in subtropical and tropical regions through out the Therapeutic use in piles world. The genus is remarkable for the large Three of four figs should be soaked overnight in In India, the water after being cleaned thoroughly in hot water. most important species of Ficus are F. bengalensis, F. They should be taken first thing in the morning along carica, Ficus racemosa and F. elastica. Ficus carica with the water in which they were soaked. They is commonly referred as “ Fig". Various parts of the should also be taken in evening in the similar plant like bark, leaves, tender shoots, fruits, seeds, manner.2, 9-11 variation in the habits of its species.22 and latex are medicinally important. The fig is a very nourishing food and used in industrial products. The 8. Hamamelis virginiana fig is a deciduous tree, to 50 ft tall, PREFACE but more typically to a height of 10 - 30 ft. The large, Hamamelis virginiana is commonly known as wavy-margined leaves are usually 5 lobed but may Witch-Hazel grows best in sun or partial shade and in have only 4 or 3 lobes. The leaves are conspicuously light, moist soil. The plant tolerates some drought palmately veined. Their branches are muscular and and grows slowly. It grows 20 to 30 feet tall and twisting, spreading wider than they are tall. Fig wood spreads 15 to 25 feet forming a multistemmed, is weak and decays rapidly. The trunk often bears shrubby, large nodal tumors, where branches have been shed Removing the lower branches helps produce a more or removed. The twigs are terete and pithy rather tree-form multistemmed specimen but regular minor latex.23- pruning will be required to maintain it in this form than woody. The sap contains copious milky round, somewhat asymmetrical ball. since the plant suckers freely from the base of the 32 trunk. The fragrant flowers are produced in late fall to mearly winter and have straplike, yellow petals and is the last shrub to flower during the year. The flowers are more interesting than ornamental, however, there are selections with more showy flowers. The fall color is yellow and often is at its Fig 7: Ficus carica peak when the flowers are out. Plants are found along Secondary metabolites stream banks in the shade in its native range where Fiber, Copper, Manganese, Magnesium, Potassium, they appear open and poorly branched. However, Calcium, Polyphenols, under cultivation in full or partial sun they develop a Arabinose, β-amyrins, β-carotines, Glycosides, β- fuller, rounded crown. Probably not for clay soils. 55 Vitamin K, Flavonoids, Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report Although galls are frequently found on the leaves, they are usually not serious pests on the plant.37 tropics and subtropics. Much of the spread and naturalization has occurred in conjunction with the spread of human populations, and as such, the mango plays an important part in the diet and cuisine of many diverse cultures. There are over 1000 named mango varieties throughout the world, which Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 is a testament to their value to humankind. Mango is a common garden tree throughout the tropics. When ripe, this delicious dessert fruit is particularly high in Fig 8: Hamamelis virginiana vitamin A. The fruit is also eaten green, processed Secondary metabolites into pickles, pulps, jams, and chutneys, and is frozen Tannin, Gallic acid, Catechins, Proanthocyanins, Kaempferol, Quercetin, Carvacro leugenol, Hexenol, Choline, and Saponins.38 or dried. The fruit is also an important source of sustenance for birds, bats, insects, and mammals. Although grown widely, mangos prefer a warm, frostfree climate with a well defined winter dry season. Therapeutic use in piles Witch hazel gel can also be used in curing hemorrhoids or bleeding piles entirely. Applying a little of witch hazel around the rectum can be advantageous in reducing the inflammation as well as hemorrhage. Witch hazel is proved to be efficient in curing the pain, burning sensation, swelling and discomfort caused due to piles. This herb is known to be one of the best astringents which can also be used Rain and high humidity during flowering and fruit development reduces fruit yields. The tree generally flowers in mid- to late winter, with fruit maturing in the early to mid-summer months. Mango trees are usually between 3 and 10 m (10–33 ft) tall but can reach up to 30 m (100 ft) in some forest situations. The canopy is evergreen with a generally spreading habit. The heavy canopy of the mango is a source of shelter and shade for both animals and human.39-41 in curing several other ailments like piles.2, 49 9. Mangifera indica PREFACE The genus Mangifera originates in tropical Asia, with the greatest number of species found in Borneo, Java, Sumatra, and the Malay Peninsula. The mostcultivated Mangifera Fig 9: Mangifera indica species, M. indica (mango), has its origins in India and Myanmar. Mangos belong to the genus Mangifera of the family Anacardiaceae. The genus Mangifera contains several species that bear edible fruit. Most of the fruit trees that are Secondary metabolites Alkaloids, Saponins, Amino acids, Carbohydrates, Glycosides, Sterols, Flavonoids, Phenolic and Tannins.42 commonly known as mangos belong to the species Mangifera indica. The other edible Mangifera species generally have lower quality fruit and are commonly referred to as wild mangos. Mango has become naturalized and adapted throughout the Therapeutic use in piles Mango seeds are an effective remedy for bleeding piles. The seeds should be collected during the mango season, dried in the shade, powdered, and kept stored for use as medicine. This powder should Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier 56 Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report be given in doses of about one and a half to two grams with or without honey, twice daily.2 scales at base, stamens usually 3, inserted toward base of hypanthium, filaments distinct, broad, anthers distinct or coherent, 2 of them dithecal, the Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 10. Momordica charantia other monothecal, cells curved or flexuous; pistillate PREFACE flowers usually solitary on a bracteate Momordica Charantia (Bitter melon or Bitter guard) hypanthium ovoid to spindle shaped, perianth is a flowering vine in the family Cucurbitaceae. usually Leaves: simple, usually palmately 5-7 lobed, tendrils staminodes absent or 3, ovules numerous, horizontal, unbranched or 2 branched. The herbaceous, stigmas 3, 2 lobed. Seeds few to numerous, ovate, tendrilbearing vine grows to 5 m. It bears simple, usually sculptured. Each plant bears separate yellow alternate leaves 4–12 cm across, with 3–7 deeply male and female flowers. Though it has been claimed separated lobes. that bitter melon’s bitterness comes from quinine, Fruit: ovoid, ellipsoid, or spindle shaped, usually no evidence could be located ridged or warty, dehiscent irregularly as a 3 valved claim.2,43 smaller than in staminate scape, flowers, supporting this fleshy capsule or indehiscent. The fruit has a distinct warty looking exterior and an oblong shape. It is hollow in cross-section, with a relatively thin layer of flesh surrounding a central seed cavity filled with large flat seeds and pith. Seeds and pith appear white in unripe fruits, ripening to red; the flesh is crunchy and watery in texture, similar to cucumber, chayote Fig 10: Momordica charantia or green bell pepper. The skin is tender and edible. The fully ripe fruit turns orange and mushy. Bitter melon comes in a variety of shapes and sizes. The Secondary metabolites typical Chinese phenotype is 20–30 cm long, oblong Glycosides, Saponins, Alkaloids, with bluntly tapering ends and pale green in color, Resins, Phenolic constituents, Fixed oil , Free acids, with a gently undulating, warty surface. The bitter Charantin, melon more typical of India has a narrower shape Cucurbitacins, with pointed ends, and a surface covered with jagged, Diosgenin, triangular "teeth" and ridges. Coloration is green or Galacturonic acids, Gentisic acid, Goyaglycosides, white. Between these two extremes is any number of Goyasaponins, intermediate forms. Some bear miniature fruit of Gypsogenin, only 6–10 cm in length, which may be served Lanosterol, Lauric acid, Linoleic acid, Linolenic acid, individually as stuffed vegetables. These miniature Momorcharasides, fruit are popular in Southeast Asia as well as India. In Momordicilin, Panama bitter melon is known as Balsamino. The Momordicosides, pods are smaller and bright orange when ripe with Multiflorenol, very sweet red seeds. acid, Oleic acid, Oxalic acid, Pentadecans, Peptides, Flowers: Staminate flowers usually solitary on a Petroselinic acid, Polypeptides, Proteins, Ribosome- bracteate scape, hypanthium shallow, calyx 5 lobed, inactivating proteins, Rosmarinic acid, Rubixanthin, petals 5, usually yellow, distinct, 1-3 with incurved Spinasterol, Steroidal glycosides, Stigmastadiols, 57 Reducing sugars, Charine, Cryptoxanthin, Cucurbitins, Cucurbitanes, Elaeostearic Guanylate acids, Cycloartenols, Erythrodiol, cyclase inhibitors, Hydroxytryptamines, Karounidiols, Momorcharins, Momordicins, Momordin, Momordenol, Momordicinin, Momordolo, Myristic acid, Nerolidol, Oleanolic Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report Stigmasterol, Taraxerol, Trehalose, Trypsin inhibitors, Uracil, Vacine, V-insulin, Verbascoside, Vicine, Zeatin, Zeatin riboside, Zeaxanthin, Zeinoxanthin, Amino acids, Aspartic acid, Serine, Glutamic acid, Thscinne, Alanine, Pipecolic acid, Ascorbigen, Beta-sitosterol-d-glucoside, Citrulline, Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 Fig 11: Oryza sativa Elasterol, Flavochrome, Lutein, Lycopene, Pipecolic acid. 44,45 Secondary metabolites Orizaterpenol, Therapeutic use in piles The juice of the fresh leaves of bitter gourd is also benzoate, Orizaterpenoid, Orizanor-diterpenyl Orizaditerpenyl benzoate Orizaterpenyl benzoate, 47-48 valuable in piles. Three teaspoons of the leaf juice, mixed with a glass of buttermilk, should be taken every morning for treating this condition. A paste of the roots of the bitter gourd plant can also be applied over piles with beneficial results.2,9-11 Therapeutic use in piles Rice has a very low fiber content and is, therefore, extremely soothing to the digestive system. A thick gruel of rice, mixed with a glass of buttermilk and a ripe banana, given twice a day, is a very nutritious 11. Oryza sativa diet for a patient with piles. 2,9-11 PREFACE An annual grass with erect culms 0.6-2 m tall usually with four to five tillers. Inflorescence a loose terminal panicle of perfect flowers; each panicle branch bearing a number of spikelets, each with a single floret. Each flower is surrounded by a lemma and palea at the base of which are two small glumes. The lemmas may be awnless or variously awned. The rice grain enclosed by the lemma and palea (hull) varies in size, texture and colour. Each panicle holds 100150 seeds. Practically all the paddy straw from rice crops in the tropics is conserved as hay for animal feeding and is usually stacked around poles in the house compound. Medling, (1972) under high rainfall 12. Ruscus aculeatus PREFACE Ruscus aculeatus (butcher’s broom) is a member of the Liliaceae family and is native to Mediterranean Europe and Africa. It has tough, green, erect, striated stems that send out numerous short branches and very rigid leaves that are actually extensions of the stem and terminate in a single sharp spine. The small greenish-white flowers grow from the center of the leaves and bloom in the early spring. The thick root, typically collected in autumn, is used medicinally. The root has no odor, but has an initially sweetish taste that then turns slightly acrid.2 conditions (3 997 mm) at Gualaca, Panama, found that baling the straw with large roller balers was effective and that the straw bales would stay in the field without major deterioration, while grass hay (Hyparrhenia rufa and other grasses) suffered serious deterioration.46 Fig 12: Ruscus aculeatus Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier 58 Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report Secondary metabolites months. Each flower is replaced by a silique that Steroidal sapogenins, Saponins, Sterols, Triterpenes, contains 2-3 seeds. This silique is rather short and Flavonoids, spongy, but it has a long beak. There is very little Glycolic acid. Coumarins, Sparteine, Tyramine, constriction between the seeds, if any. The seeds are 49-54 oval-shaped, slightly flattened, and reddish brown. Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 Therapeutic use in piles The root system consists of a stout taproot that is Butcher’s broom is proved to be one of the commonly somewhat fleshy. It is often reddish, but other color used herbs in the case of piles. Steroids like forms occur. This plant spreads by reseeding itself. ruscogenins are found to be present in this herb, The preference is full sun and moist to mesic soil that namely butcher’s broom. Studies have revealed that is fertile and loamy. The Garden Radish also does these steroids can very effectively help in reducing well in slightly sandy soil if it is sufficiently moist and the tenderness as well as bleeding due to the problem fertile. It develops rapidly from seed during the of piles. Taking small quantities of its extract spring and bolts during hot summer weather. The everyday can be helpful in strengthening the blood leaves often have holes from various insect pests.56 vessels as well as preventing the problem to an extent.55 13. Raphanus sativus PREFACE Raphanus sativus introduced annual or biennial Fig 13: Raphanus sativus plant consists of a rosette of leaves; somewhat later, it bolts and produces flowering stems up to 2½' tall. Secondary metabolites The basal leaves are up to 7" long and 2½" across; Raphanin, Glucosilinates, Vitamin C, Volatile oil.57 they are oblanceolate, coarsely crenate, and pinnately lobed. These lobes may be shallow or deep; the Therapeutic use in piles terminal lobe is always the largest. The surface of the White radish is considered highly valuable in piles; basal leaves is usually rough from stiff hairs. The 100 mg of grated radish mixed with a teaspoon of central stem is often reddish at the base, but light honey may be taken twice daily. This vegetable can green elsewhere; it is either glabrous or covered with also be taken in the form of juice mixed with a pinch scattered stiff hairs. The upper side stems are very of salt. White radish, well ground into a paste in milk similar, except that there is often a red ring where can also be applied over inflamed pile masses to they branch from the central stem. The alternate relieve pain and swelling. 57 leaves on the stems are similar in appearance to the basal leaves, except that they are smaller, less likely 14. Sesamum indicum to be deeply lobed, and narrowly ovate in shape. The PREFACE central and upper stems terminate in racemes of Sesamum indicum Linn. (Pedaliaceae) is an annual flowers. Each flower is about 1/3" across, consisting shrub with white bell-shaped flowers with a hint of of 4 pink or light purple petals, 4 light green sepals blue,red or yellow with branches or without that are linear-oblong, a central pistil, and several branches.It is grown for the production of seeds stamens with yellow anthers. The blooming period which is rich in oil content. It comes in a variety of occurs during the summer and lasts about 1–1½ colors, cream-white to charcoal-black. In general, the 59 Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 paler varieties ofsesame seem to be more valued in Therapeutic use in piles West and Middle East, while the black varieties are Sesame seeds are also valuable in piles. They can be prized in the Far East. It is commonly known as Til taken in the form of a decoction by boiling twenty (Hindi), hu ma (Chinese), sésame (French), goma grams of seeds in 500 ml of water till it is reduced by (Japanese), gergelim (Portuguese) ajonjolí one-third, or as sweetmeats. Ground to paste with (Spanish). Sesame is found in tropical, subtropical, water, they can be given with butter for bleeding and piles.2,9-11 southern temperate areas and of the world, particularly in India,China, SouthAmerica and Africa. It has utmost economical importance and is 15. Syzygium cumini primarily grown by small farmers in developing PREFACE countries. The plant grows best in tropical climates The genus Syzygium is one of the genera of the (spring to fall). Sesame grows best in sandy myrtle family Myrtaceae which is native to the welldrained soil with hot climate and moderate tropics, rainfall. It is propagated by seed sown in spring and Australia. It has a worldwide, although highly it takes about four months for the seeds to ripen fully. uneven, distribution in tropical and subtropical Depending on conditions, varieties grow from about regions. The genus comprises about 1 100 species, 0.5 to 2.5 m tall. The leaves are ovate, opposite, grow and has a native range that extends from Africa and alternately up the stem and are deeply veined. The Madagascar through southern Asia east through the flowers are white, shaped like a trumpet, on short Pacific. Its highest levels of diversity occur from peduncles in axils of leaves. The fruit, is about 2.5 cm Malaysia to northeastern Australia, where many (l) is an oblong capsule with small seeds. Each plant species are very poorly known and many more have may grow 15-20 fruits, which contain 70-100 seeds. not been described taxonomically. Plants of this Plants and fruits mature in 80-100 days after sowing. family are known to be rich in volatile oils which are In threshing, capsule bursts open and seeds are reported for their uses in medicine65 and many fruits scattered. Finally the seeds are cleaned, dried and of the family have a rich history of uses both as packed in gunny bags.58 particularly to tropical America and edibles and as traditional medicines in divergent ethnobotanical practices throughout the tropical and subtropical world.66 Some of the edible species of Syzygium are planted throughout the tropics worldwide. Jambolan is a large evergreen and densely foliaceous mtree with greyish-brown thick bark, exfoliating in woody scales. The wood is Fig 14: Sesamum indicum whitish, close grained and durable; affords brown dyes and a kind of a gum Kino. The leaves are Secondary metabolites Sesamin , Sesamolin, Chlorosesamone Sesaminol, leathery, oblong-ovate to elliptic or obovate-elliptic 8-dihydroxy-3- with 6 to 12 centimeters long (extremely variable in Sesamol, (2-chloro- 5, 3methyl-2-butenyl)-1,4-naphthoquinone), shape, smooth and shining with numerous nerves Phenylethanoid uniting within the margin), the tip being broad and glycosides, Sugarsequence, Sesamolinol, Anthrasesamones A, B and C 59-64 less acuminate. The panicles are borne mostly from the branchlets below the leaves, often being axillary or terminal, and are 4 to 6 centimeters long. Flowers Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier 60 Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report are scented, greenish-white, in clusters of just a few every morning for two or three months during its or 10 to 40 and are round or oblong in shape and season.2 found in dichotomous paniculate cymes. The calyx is funnel-shaped, about 4 millimeters long, and 16. Triticum aestivum Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 toothed. The petals cohere and fall all together as a PREFACE small disk. The stamens are numerous and about as T. aestivum known only under cultivation; its long as the calyx. Several types, which differ in colour nativity has been lost. Wheat evolved from wild and size of fruits, including some improved races grasses, probably somewhere in the Near East. A very bearing purple to violet or white coloured flesh and likely place of origin is the area known in early seedless fruits have been developed. The fruits are historical times as the Fertile Crescent, a region with berries and are often obviously oblong, 1.5 to 3.5 rich soils in the upper reaches of the Tigris- centimeters long, dark-purple or nearly black, Euphrates luscious, fleshy, and edible; it contains a single large simple, erect, hollow or pithy, glabrous, up to 1.2 m The plant produces small purple plums, tall; leaves flat, narrow, 20–38 cm long, about 1.3 cm which have a very sweet flavor, turning slightly broad; spikes long, slender, dorsally compressed, astringent on the edges of the pulp as the fruit somewhat flattened; rachis tough, not separating becomes mature. The dark violet colored ripe fruits from spikelet at maturity; spikelets 2–5-flowered, give the impression the fruit of the olive tree both in relatively far apart on stem, slightly overlapping, weight and shape and have an astringent taste. The nearly erect, pressed close to rachis; glumes keeled in fruit has a combination of sweet, mildly sour and upper half, firm, glabrous, shorter than the lemmas; astringent flavour and tends to colour the tongue lemmas awned or awnless, less than 1.3 cm long; purple. 69 palea as long as the lemma, remaining entire at seed67,68 drainage basin.Annual grass; culms maturity; caryopsis free-threshing, soft or hard, red or white. Hexaploid.74 Fig 15: Syzygium cumini Secondary metabolites Anthocyanins, Glucoside, Ellagic acid, Isoquercetin, Kaemferol myrecetin, Alkaloid, Jambosine, Glycoside jambolin or Antimellin Protein Calcium. Sugar, Mineral salts, Vitamins C, Vitamin C, Anthocyanins, Flavonoids.67, 70-73 Fig 16: Triticum aestivum Secondary metabolites Tocopherols (vit. E), Essential fatty acids, Sitosterol, Ergosterol, Campesterol, Phospatidic, Glyceroinositophosphatidic acids, Phytoglycolipid, Serine 74,75 Therapeutic use in piles The jambul fruit is another effective remedy for bleeding piles. The fruit should be taken with salt Therapeutic use in piles Wheat grass juice used as an enema helps detoxify the walls of the piles. The general procedure is to give 61 Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report an enema with lukewarm or neem water. After spreading branched found throughout the greater waiting for twenty minutes, 90 to 120 ml of the wheat parts of India. Bark dark brown often longitudinally grass juice enema is given. This should be retained cracked, exfoliating in woody scales, Leaves ovate or for fifteen elliptic with a pair of large gland at the tip of the minutes.2,9-11 pedicel Flowers yellowish white; in terminal spikes, Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 17. Terminalia chebula drupes ellipsoidal, obovoid or ovoid, yellow to orange PREFACE brown, sometimes tinged with red or black and hard Terminalia Chebula is called the "king of medicines" when ripe. 3-5cm long becomes 5 ribbed on in Tibet and is always listed first in the Ayurvedic drying. Fruits the ovoid, yellow to orange brown meteria medica because of its extraordinary powers fruits are 2.5 to 4.0cms long. Usually 5- angled when of healing. In Ayurveda it is considered to destroy all dry, stone very think, bony, obsurely angled, rough, diseases and eliminate all waste from the body. At the grooved, having gum vessels on the wall.76 same time, it is known to promote tissue growth and health. Modern science has found that Terminalia Chebula has a strong effect against the herpes simplex virus HSV, has antibacterial activity, and exhibits strong cardio tonic properties. Terminalia Chebula also has antioxidant components, which indicates it can increase the life of tissues. Yet Fig 17: Terminalia chebula another study shows the anti-tumor activity of Terminalia Chebula and another study shows that it Secondary metabolites has considerable effect in inhibiting the HIV virus Tannic which ultimately results in AIDS Thus, Terminalia Anthraquinone, Sennoside, Ellagic acid, Chebulic Chebula can be seen to be a valuable addition to acid, Gallotannins such as 1,6 di-O-galloyl-β-D- anyone's herbal collection. With its rejuvenating and glucose, cleansing properties, Terminalia Chebula is excellent tetra-O-galloyl-β-D-glucose, 1,2,3,4,6 penta-Ogalloyl- for β-D-glucose. Ellagitannin such the digestive system. As a preventative acid, Chebulinic acid, Gallic acid, 3,4,6 tri-O-galloyl-β-D-glucose, 2,3,4,6 as Punacalagin, supplement it has great anti viral attributes, as Casurarinin, Corilagin and Terchebulin Chebulanin, shown by its anti tumor and HIV action. It is also Neochebulinic acid, Chebulagic acid, chebulinic acid. effective for alleviating constipation in general, and is 77-83 helpful for vata persons because it works in the Triphala formula which is a well balanced digestive Therapeutic use in piles and rejuvenating aid. Terminalia chebula is found in The herb chebulic myroblan is a popular remedy for the sub Himalayan tracks form Ravi eastwards to piles. The fruit should be roasted to a brown color in west Bengal and Assam, ascending up to at altitude of cluster oil, and then powdered and stored. Half a 1500m in the Himalayas, In the This tree is wild in teaspoon of this powder at bedtime will bring about the forests of Northern India, central provinces And normal bowel movements in the morning. A Bengal, common in madras, Mysore and in the decoction of the herb prepared by boiling six 10 seven southern presidency. dry fruits in half a litre of water should be used for A tree 15.24m in height & 1.5-2.4m in girth with a washing bleeding piles. The paste of the fruit mixed cylindrical bole of 4-9m, a rounded crown and in bland oil is good as an external application.2,50 Parts of the Bombay Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier 62 Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report 18. Vaccinium myrtillus Therapeutic use in piles PREFACE Bilberry can also be used in the treatment of piles Vaccinium myrtillus (bilberry) is a member of the which is a unanimously used herbal remedy for the Ericaceae family, and is also known as European problem of same. The presence of bioflavonoid blueberry, huckleberry, whortleberry, or blueberry. It makes the herb useful in curing bleeding piles by is a shrubby perennial plant one to two feet in height improving the blood flow very efficiently.2 Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 and can be found in the mountains and forests of Europe and the northern United States. Its branches 19. Verbascum thapus L. contain alternating, elliptical, bright green leaves, PREFACE and its flowers, which appear from April to June, are Verbascum thapsus is an herbaceous plant native to reddish or pink, and bell-shaped. The fruit of the Europe that bilberry plant is blue-black or purple and differs from temperate areas of the world, including North the American blueberry in that the meat of the fruit is America, Hawai'i, Reunion, Australia, and New purple, rather than cream or white. Fruit is harvested Zealand. The plant can become invasive by quickly July through September, and time of ripeness is colonizing disturbed areas. V. thapsus plants produce somewhat dependent on plant elevation. Plants numerous seeds that may remain dormant in the soil growing at higher elevations generally ripen later for over 100 years. V. thapsus is a state noxious weed than those at lower elevations. Bilberry has been used in Colorado and Hawai'I. as food for centuries due to its high nutritive value, In Hawai'i, V. thapsus is known from the Island of and today represents a precious wild delicacy. Hawai'i, where it infests roadsides at elevations from Bilberry’s history of medicinal use dates back to the 5,000-10,000 ft (1,524-3,048 m) and is particularly Middle Ages, but it did not become widely known to dense around 6,562 ft (2,000 m) forming a herbalists until the 16th century when its use was monotypic cover that can out-compete native documented for treating bladder stones, biliary vegetation. It is feared that V. thapsus could do the disorders, scurvy, coughs, and lung tuberculosis. same in similar native alpine ecosystems on Maui. In More recently, bilberry fruit extracts have been used the 1980's, two plants were detected and eradicated for the treatment of diarrhea, dysentery, and mouth in Haleakala National Park. In addition, plants were and throat inflammations. Bilberry leaf decoctions being cultivated by a plant grower in Kula. All plants have been used to lower blood sugar in diabetes.84 is cultivated and naturalized in have been destroyed. Recently, V. thapsus was again observed being cultivated in Kula. Early detection and control in natural areas as well as public education on noxious weed species are both needed to help keep V. thapsus from invading on Maui. "Stout biennial herbs 3-20 dm tall in the second year, densely yellowish wooly tomentose throughout, the hairs stellate or dendritic. Basal leaves obovate to Fig 18: Vaccinium myrtillus Secondary metabolites Anthocyanins, Vitamins, Sugars, Pectins, Quercetin, Catechins, Tannins, Iridoids. 85-90 63 oblanceolate, 8-50 cm long, 2.5-14 cm wide, densely yellowish or whitish wooly tomentose, margins entire to shallowly crenate; cauline leaves becoming progressively smaller toward the inflorescence, oblanceolate, sessile and decurrent on stem. Flowers Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 in compact, spikelike panicles, pedicels partly adnate commercial crop for the ginger root in Latin America to the stem; calyx (5-)8-12 mm long, the lobes and Africa as well as South East Asia. Fifty percent of lanceolate; corolla yellow, rarely white, 8-15 mm worldwide ginger production is in India. The best long, scurfy pubescent externally, sometimes also quality ginger comes from Jamaica. The common ciliate, the hairs stellate; upper 3 staminal filaments cooking ginger is an herbaceous perennial with villous with yellow hairs, the lower 2 glabrous to upright stems and narrow medium green leaves sparsely villous. Capsules broadly ovoid to elliptic- arranged in two ranks on each stem. The plant gets ovoid, 0.7-1 cm long, densely tomentose with stellate about 4 ft (1.2 m) tall with leaves about 3/4 in (1.9 or branched hairs. cm) wide and 7 (17.8 cm) long. Ginger grows from an 91,92 aromatic tuber like rhizome (underground stem) which is warty and branched. The inflorescence grows on a separate stem from the foliage stem, and forms a dense spike, to 3 in (7.6 cm) tall. The bracts are green with translucent margins and the small flowers are yellow green with purple lips and cream colored blotches. Most gingers in cultivation are Fig 19: Verbascum thapus L. sterile cultivars grown for the edible rhizome, and the Secondary metabolites Saponins, Iridoid, Monoterpene flower is rarely seen.There is a cultivar of Zingiber Phenylethanoid glucoside, Neolignan glycosides, glucosides, Flavonoids, Steroids, Spermine, alkaloids. Phenolic acids and rhamnoside, fatty acids Luteolin, such as Apigenin-4’- Verbacoside, dihydroxyflavon-4-rhamnoside, 7,4’- 5-hydroxy-6,7- dimeth oxyflavone-3-ol 93 officinale known as 'Sunti', which comes from Java and is similar to the common cooking ginger, but forms smaller rhizomes. It is used in the same way as common ginger but is said to have better medicinal qualities. Ginger root is widely used around the world as a spice or food additive. Ginger is fried and eaten plain, and used in curry pastes and other sauces in India; it is grilled and used to flavor fish and meats or Therapeutic use in piles Mullein flower extract is considered as an effective alleviating substance which can be used in treating the problem of piles and other ailments. Mullein leaf extract can also be utilized in curing piles very effectively. The anti inflammatory properties of mullein extract is found to be beneficial in reducing the dilation of veins and hence relieving from the for making ginger tea in Indonesia; it is boiled or fried in Chinese cookery; used to baste chicken or eaten as pickled ginger (beni shoga) and served with sushi in Japan; and used in Jamaica to make Jamaican jerk paste. A ginger extracts with carbonated water makes the popular drink we call ginger ale. Ginger was used in the middle ages in Europe to flavor beer. 94-99 discomfort caused due to the same. This is one of the widely used herbal tonics for curing hemorrhoids.2, 911 20. Zingiber officinale PREFACE Zingiber officinale or common cooking ginger originated in tropical Asia, but is now grown as a Fig 20: Zingiber officinale Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier 64 Km. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report 9) Secondary metabolites al/mgmh/c/chehor58.html Zingerone, Shogaolsand gingerols, Volatile oils, [6]gingerol(1-[4'-hydroxy-3'-methoxy of ginger. 10) CR Review Paper Covered in Index Copernicus with IC Value 4.68 for 2010 Bisabolene, Arnesene , 11) β-phelladrene, Cineol, 13) of honey, constitutes an effective 14) 15) http://www.permanente.net/homepage/kaiser/pdf Modern Medicinal Km. Ruby, R Chauhan, S Sharma, J Dwivedi. R Chauhan, Km. Ruby, J Dwivedi. Bergenia ciliata Pharm. Sci. Rev. Res. .2012; 15(2):4: 20-23. 16) Km. Ruby, R Chauhan, J Dwivedi. Cure of Hemorrhoids Using Indian Medicinal Academic Publishing, Germany. 17) Lambert Academic Publishing Germany. Aesculus hippocastanum http:// plants L. (horse .usda Chauhan R, Km. Ruby, Dwivedi J. Natural Product Part-I Berginia: A complete study. 2012. Lambert Plants: Hemorrhoids Cure With The Help Of Herbs.2012. Chauhan R, Km. Ruby, Dwivedi J. Pashanbheda a golden herb of Himalaya: A Review. Int. J. Pharm. chestnut). .gov /jav Sci. Rev. Res..2012;15(2):5: 24-30. 18) R Chauhan, Km. Ruby, J Dwivedi. Himalayan a/profile?symbol=AEHI [Accessed June 16, 2009] Bergenia a comprehensive review. Int. J. Pharm. Aesculushippocastanum.http://en.wikipedia.org/wi Sci. Rev. Res. 2012;14(2):24:139-141 ki/Aesculus_hippocastanum 19) Alternative Medicine Review Volume 14, Number 3 2009 Aesculus hippocastanum (Horse Bombardelli E, http://www.hort.purdue.edu/newcrop/duke_energ y/brassica_rapa.html 20) BK Watt AL Merrill. Composition of foods. USDA, chestnut).monograph ARS, Washington, DC. Agr. Handb. 8.1963 Morazzoni P. Aesculus 21) W Leung, W Tsuen, RR Butrum, FH Chang. Part I. hippocastanum L. Fitoterapia 1996:67;483-511. Proximate D Lorenz, ML Marek. The active therapeutic contents of east Asian foods. In: Food composition principle table for use in east Asia. FAO & U.S. Dept. of horse chestnut (Aesculus hippocastanum). Part 1. Classification of the active substance. Arzneimittelforschung 1960;10:263- composition mineral and vitamin HEW.1972 22) EA Jander, KC Machado. Evolutionary ecology of 272. figs and their associates: Recent progress and U Mrwa, K Guth, C Haist. Calcium-requirement for outstanding activation of skinned vascular smooth muscle from 2008:39;439-458 spontaneously normotensive 196. 65 Ross IA. Medicinal Plants of the world: Chemical mine of medicinal properties:A Review. Int. J. /5272.pdf 8) http://www.pfaf.org/user/Plant.aspx?LatinName= Int. J. Pharm. Sci. Rev. Res.2012;13(1):100-110. References 7) 11.Horsechestnut(AesculushippocastanumL.).http:/ Polypharmacological activity of Bergenia species. medicine for piles. 2,9-11 6) profile. Uses, Humana Press, Totowa,2001:2;19. fresh lime juice and fresh mint juice, and a 5) therapeutic Constituents, Traditional and of fresh ginger juice, mixed with one teaspoon each of 4) and pharmacology, Allium+cepa Ginger is also useful in this disease. Half a teaspoon 3) Aescin: patient-horsechestnut [Accessed June 16, 2009] Therapeutic use in piles 2) 16, /www.mayoclinic.com/health/horse-chestnut/NS_ 12) 1) June Pharmacol Res 2001:44;183-193. Andcitral.94-99 tablespoon Sirtori. pharmacokinetics Aresesquiterpenoids, (-)- Zingiberene sesquiterpenoids,β-sesquiphellandrene, [Accessed 2009] phenyl]-5- hydroxy-3-decanone) is the major pungent principle Chestnut,Horse.http://www.botanical.com/botanic hypertensive (SHRSP) puzzles. Ann Rev Evol. Syst. , and 23) JA Vinson, L Zubik, P Bose, N Samman, J Proch. control rats. Life Sci 1986:38;191- Dried fruits: excellent in vitro and in vivo antioxidants. J. Am. Coll. Nutr.2005: 24(1); 44-50. Int. J. Drug Dev. & Res., October-December 2012, 4 (4): 50-68 Covered in Scopus & Embase, Elsevier K. M. Ruby et al: Golden Herbs used in Piles Treatment: A Concise Report 24) McGovern TW. The fig-Ficus carica L. Cutis 2002: 36) JA 69;339-40. 25) S CM Kasum. 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