NPUAP - EPUAP Pressure Ulcer Prevention & Treatment Guidelines
Transcription
NPUAP - EPUAP Pressure Ulcer Prevention & Treatment Guidelines
NPUAP-EPUAP Pressure Ulcer Prevention & Treatment Guidelines [ [ Janet Cuddigan, PhD, RN, CWCN Associate Professor & Department Chair University of Nebraska Medical Center Omaha, NE USA Editor-in-Chief, EPUAP-NPUAP Guideline Walk Through the Treatment Guidelines with Us! ©NPUAP & EPUAP, 2009 2 Treatment Topics • Classification • Assessment & Monitoring Healing • Nutrition for Healing • Pain Assessment & Management • Support Surfaces • Cleansing • Debridement • Dressings • Assessment & Treatment of Infection…. ©NPUAP & EPUAP, 2009 3 Treatment Topics • Biophysical Agents • Biological Dressings • Growth Factors • Surgery for Pressure Ulcers • Pressure Ulcer Management in Individuals Receiving Palliative Care ©NPUAP & EPUAP, 2009 4 Treatment Topics ©NPUAP & EPUAP, 2009 5 Classification of Pressure Ulcers • New Components – Use validated system • NPUAP Staging & EPUAP Grading • NPUAP-EPUAP International System – Educate professionals (B) – Confirm inter-rater reliability (B) – Do not classify pressure ulcers on mucous membranes ©NPUAP & EPUAP, 2009 6 Educate professionals about special assessment techniques in individuals with darkly pigmented skin. (B) 1. Skin Intact: Stage I and suspected deep tissue injury may be difficult to detect with visual inspection alone. Assess differences in skin temperature, skin color, tissue consistency (i.e. boggy or firm) and pain between affected areas and normal tissue. 2. Skin Open: Inflammatory redness of the surrounding skin may be difficult to detect in Stage II through IV pressure ulcers. Assess for heat, tenderness, pain or change in tissue consistency to identify the extent of inflammation and possible cellulitis and/or undermining. • Baumgarten M, Margolis D, van Doorn C, Gruber-Baldini AL, Hebel JR, Zimmerman S, et al. Black/White differences in pressure ulcer incidence in nursing home residents. J Am Geriatr Soc. 2004 Aug;52(8):1293-8 ©NPUAP & EPUAP, 2009 7 Stage/Category II - IV ©NPUAP & EPUAP, 2009 8 NPUAP-EPUAP International Classification System© • We agree on: – Definition of pressure ulcers – Definition of four “stages, grades, or categories” – Additional categories for USA • Suspected Deep Tissue Injury • The “Unstageables” – Stage? Grade? Category? ©NPUAP & EPUAP, 2009 9 I: Non-blanchable erythema of intact skin Intact skin with nonblanchable erythema of a localized area usually over a bony prominence. Discoloration of the skin, warmth, edema, hardness or pain may also be present. Darkly pigmented skin may not have visible blanching. ©NPUAP & EPUAP, 2009 10 II: Partial thickness skin loss or blister • Partial thickness loss of dermis presenting as a shallow open ulcer with a red pink wound bed, without slough. May also present as an intact or open/ruptured serum or sero-sanguinous-filled blister. ©NPUAP & EPUAP, 2009 11 III: Full thickness skin loss • Full thickness skin loss. Subcutaneous fat may be visible but bone, tendon or muscle are not exposed. Some slough may be present. May include undermining and tunneling. ©NPUAP & EPUAP, 2009 12 IV: Full thickness tissue loss • Full thickness tissue loss with exposed bone, tendon or muscle. Slough or eschar may be present. Often includes undermining and tunneling. ©NPUAP & EPUAP, 2009 13 Full thickness skin or tissue loss – Depth unknown • Full thickness tissue loss in which actual depth of the ulcer is completely obscured by slough (yellow, tan, gray, green or brown) and/or eschar (tan, brown or black) in the wound bed. ©NPUAP & EPUAP, 2009 14 Suspected deep tissue injury – depth unknown • Purple or maroon localized area of discolored intact skin or blood-filled blister due to damage of underlying soft tissue from pressure and/or shear. ©NPUAP & EPUAP, 2009 15 Assessment & Monitoring Healing • New Components – Holistic patient assessment – Pressure ulcer assessment (at least weekly) – How to measure (B) – Expect some signs of healing in 2 weeks (B) – Assessment findings should guide treatment – Changing assessment → changing treatment – Assess progress toward healing with a validated tool (B) • Bates-Jensen Wound Assessment Tool (BWAT) • Pressure Ulcer Scale for Healing (PUSH) ©NPUAP & EPUAP, 2009 16 Nutrition for Pressure Ulcer Healing • Most patients with PU suffer from undernutrition • Nutritional requirements usually increase to support PU healing. • Assess nutritional status – Mini-Nutritional Assessment (MNA) validated & easy to use in multi-morbid geriatric patients. – MUST (Malnutrition Universal Screening Tool) – to ID risk of undernutrition – Child: assess weight, height, head circumference, body mass index, skin fold plot, compare to age – Miffin-St Jeor equation for bariatric patients ©NPUAP & EPUAP, 2009 17 Nutrition for Pressure Ulcer Healing • Provide sufficient nutrients & fluids. – Kilocalories (B) (30- 35 kcal/kg/day) – Protein to promote anabolism (B) (1.25 – 1.5 gm/kg/day). Assess renal function – Vitamins & minerals with balanced diet; supplements with deficiencies. (B) – Enhanced foods or oral supplements (B) – Fluids. Assess for dehydration. (Hartgrink, et. al, 1998; Lee, et al, 2006; Langenkamp-Henken, et al, 2000; Langer, et al, 2003) ©NPUAP & EPUAP, 2009 18 Pain Assessment & Management • Minimal evidence for management of PrU pain • Individuals with a PrU experience pain; individuals with a Stage IV PrU experience greater pain than those with ↓stage PrU • Only 2% of patients in 1 study who reported PrU pain had received timely analgesia after c/o pain (Dallam et al., 1995) ©NPUAP & EPUAP, 2009 19 Pain Assessment & Management • Assess for pain • Prevent pain • Manage general pain • Reduce debridement pain • Manage chronic pain • Educate Individuals, Family and Professionals ©NPUAP & EPUAP, 2009 20 Prevent Pain - Avoid postures that increase pressure, such as Fowlers >30° or 90° side lying position, or the semirecumbent position. -Use dressings less likely to cause pain (HD, HDG, hydrofiber, alginates, foam, polymeric foam, soft silicone, ibuprofenimpregnated [not available everywhere]). ©NPUAP & EPUAP, 2009 21 Local Treatment of Pain • Consider topical opioids (diamorphine or benzydamine 3%) to reduce or eliminate PU pain. (B) – Topical anesthetics act on opioid receptors in peripheral nerves that are activated during inflammation – Morphine or Diamorphine gel, foam dressing with ibuprofen [not available everywhere] (Flock, et al, 2003; Twillman, et al, 1999; Gottrup, et al, 2007) ©NPUAP & EPUAP, 2009 22 Chronic Pain - For chronic pain, follow the World Health Organization Dosing Ladder - Refer the individual with chronic pain related to PU to the appropriate pain and/or wound clinic resources. ©NPUAP & EPUAP, 2009 23 Support Surfaces for Treatment of Pressure Ulcers • New Components – S3I Terms & Definitions – Pressure Redistribution – Growing Appreciation of Microclimate • Local tissue temperature & moisture at bodysupport surface interface. – Need for Standards: ISO Initiative – Need to match patient needs to support surface features ©NPUAP & EPUAP, 2009 24 The term, “upgraded support surface” is used throughout this document to prompt the professional to consider replacing the existing support surface only one of several strategies. The individual and pressure ulcer should be re-evaluated. Preventive interventions and local wound care should also b Support Surfaces for Treatment of Pressure Ulcers • Replace the existing support surface with one that provides better pressure redistribution if the individual – – – – – can’t be turned off the ulcer, has PU on 2 or > surfaces, fails to heal or shows deterioration, I is at hi risk for additional PU, or bottoms out on existing surface. ©NPUAP & EPUAP, 2009 25 The term, “upgraded support surface” is used throughout this document to prompt the professional to consider replacing the existing support surface only one of several strategies. The individual and pressure ulcer should be re-evaluated. Preventive interventions and local wound care should also b Support Surfaces for Treatment of Pressure Ulcers • When pressure ulcers deteriorate or fail to heal, changing the support surface is only one of several strategies. The individual and pressure ulcer should be re-evaluated. Preventive interventions and local wound care should also be changed as needed. ©NPUAP & EPUAP, 2009 26 The term, “upgraded support surface” is used throughout this document to prompt the professional to consider replacing the existing support surface only one of several strategies. The individual and pressure ulcer should be re-evaluated. Preventive interventions and local wound care should also b Support Surfaces for Treatment of Pressure Ulcers • General recommendations – Support surfaces – Positioning • Support surfaces for: • • • • Stage I & II (bed & chair) Stage I & II of heels Deep tissue injury Stage III, IV & unstageable (bed & chair, heels) ©NPUAP & EPUAP, 2009 27 The term, “upgraded support surface” is used throughout this document to prompt the professional to consider replacing the existing support surface only one of several strategies. The individual and pressure ulcer should be re-evaluated. Preventive interventions and local wound care should also b Support Surfaces for Treatment of Pressure Ulcers • Special Populations – Critically ill • Hemodynamic instability – Spinal cord injury – Bariatric • Fit individual to bed at admission ©NPUAP & EPUAP, 2009 28 Wound Bed Preparation and Biofilms • Guiding Principles of Wound Bed Preparation – – – – Tissue Infection/ inflammation Moisture Epithelium/edges Schultz GS, Sibbald RG, Falanga V, Ayello EA, Dowsett C, Harding K, Romanelli M, Stacey MC, Teot L, Vanscheidt W. Wound bed preparation: a systematic approach to wound management. Wound Repair Regen 11 Suppl 1:S1-S28, 2003 ©NPUAP & EPUAP, 2009 29 Cultures & Biofilms • Do standard specimen processing procedures detect biofilms and the organisms encased in biofilms? • How do we remove biofilms? • Once removed, how to we prevent biofilms from re-forming? ©NPUAP & EPUAP, 2009 30 po ly mi cro bi al bi of i lm ma tu re re ve rs ib le att ac hm en irr ev t ers ib le att ac m icr hm oc en ol o t ni e s bi of ilm How Do Bacterial Biofilms Form? Five stages of biofilm development in Pseudomonas aeruginosa. In Stage 1, bacterial cells attach reversibly to the surface. At Stage 2, the cells attach irreversibly, mediated by exopolymeric substances, and loose flagella-driven motility. In Stage 3, the first biofilm architecture occurs, forming microcolonies, while in Stage 4 the fully mature biofilm architecture is achieved. In Stage 5, dispersion of single motile cells occurs from the mature biofilm, which ‘seed’ other surfaces, re-initiating the process. Graphic and photos by Peg Dirckx, David Davies and Karin Sauer ©NPUAP & EPUAP, 2009 31 Cleansing • New Components – Cleanse pressure ulcer & surrounding skin (B) – Normal saline or potable water – Consider solutions with surfactants and antimicrobials with • Debris • Confirmed or Suspected Infection • High levels of bacterial contamination – Konya, et al. 2005 ©NPUAP & EPUAP, 2009 32 Debridement • Debride devitalized tissue when appropriate to individuals condition and goals – – – – – Appropriate method Choice of methods, but surgical for spreading infection Manage pain Vascular assessment Stable heel ulcers • Maintenance debridement until wound bed is covered with granulation tissue and devoid of necrotic. • Pain management related to debridement ©NPUAP & EPUAP, 2009 33 Dressings • • Ulcer should be assessed at every dressing change & the appropriateness of the current dressing regimen should be confirmed. Evidence was summarized for the following dressing types: – Hydrocolloid (B) – Transparent film – Hydrogel (B) – Alginate (B) – Foam (B) – Polymeric membrane dressings (B) – Impregnated dressings (silver, honey, cadexomer iodine) (B) – Gauze dressings – Silicone coated dressings (B) – Collagen dressings – Composite dressings ©NPUAP 11th National & EPUAP, NPUAP2009 Biennial Conference • February 27–28, 2009 34 Dressing Highlights Protection from Friction & Shear • Consider using dressings to protect body areas at risk for friction injury or risk of injury from tape. • Consider placing foam dressings on body areas & PUs at risk for shear injury. Reduction of Bioburden • Consider using silver dressings in infected or heavily colonized ulcers (B) (Munter, et al, 2006) – may be toxic to keratinocytes & fibroblasts – Silver resistant strains of bacteria may be emerging – Avoid prolonged use; discontinue when infection controlled • • Consider medical grade honey for II & III (Gunes & Esser, 2007) Consider cadexomer iodine dressings in moderately to heavily exudating wounds (Moberg, et al., 1983) ©NPUAP & EPUAP, 2009 35 Dressings - Highlights • When other forms of moisture retentive dressings are not available, continually moist gauze is preferable to dry gauze. • Consider silicone dressings to promote atraumatic dressing changes, especially when tissue is friable. (Meamue, 2003) • Consider collagen matrix dressings for non healing full thickness PrUs. ©NPUAP 11th National & EPUAP, NPUAP2009 Biennial Conference • February 27–28, 2009 36 Assessment & Treatment of Infection • Infected ulcers don’t heal! • Have a high index of suspicion for likelihood of infection if: Ulcer has necrotic tissue or foreign body; large and deep; long duration; frequently contaminated – Individual has undernutrition, diabetes mellitus, hypoxemia, poor tissue perfusion, autoimmune disease or immunosuppression – ©NPUAP & EPUAP, 2009 37 Assessment & Treatment of Infection Have a high index of suspicion for local infection in pressure ulcers when there are no signs of healing for 2 weeks, friable granulation tissue, foul odor, increased pain in the ulcer, increased heat in the tissue around the ulcer, increased drainage from the wound, an ominous change in the nature of the wound drainage (e.g., new onset of bloody drainage, purulent drainage), increased necrotic tissue in the wound bed, pocketing or bridging. (Strength of Evidence = B.) Cutting KF, Harding KG. Criteria for identifying wound infection. J Wound Care. 1994;3(4):198-201. Gardner SE, Frantz RA, Doebbeling BN. The validity of the clinical signs and symptoms used to identify localized chronic wound infection. Wound Repair Regen. 2001;9(3):178-86. ©NPUAP & EPUAP, 2009 1 38 How do we assess wound infection? ©NPUAP & EPUAP, 2009 39 Assessment & Treatment of Infection: Diagnosis • • • Early diagnosis of spreading acute infection: erythema beyond ulcer edge, induration, new or increasing pain, warmth, purulent drainage, crepitus or discoloration of skin, increasing ulcer size, signs of systemic infection. Determine bacterial bioburden: – Quantitative tissue culture (Gold Standard) – Quantitative swab technique (Levine technique) Consider the diagnosis of pressure ulcer infection if the culture results indicate bacterial bioburden of > 105 CFU/g of tissue and/or the presence of beta hemolytic streptococci. ©NPUAP & EPUAP, 2009 40 Assessment & Treatment of Infection: Management • • • • • Optimize host. Prevent contamination. Reduce bacterial load with cleansing & debridement. Drain local abscesses. Consider the use of topical antiseptics that are properly diluted and appropriate for pressure ulcers. Antiseptics should be used for a limited time period to control the bacterial bioburden, to clean the ulcer and reduce surrounding inflammation. The professional should be knowledgeable of proper dilutions, as well as risks of toxicity and adverse reactions. Consider topical antiseptics for pressure ulcers that are not expected to heal and are critically colonized. Consider the use of topical antimicrobial silver or medical-grade honey dressings for pressure ulcers infected with multiple organisms because these dressings offer broad antimicrobial coverage. ©NPUAP & EPUAP, 2009 41 Assessment & Treatment of Infection: Management • • • Limit the use topical antibiotics on infected pressure ulcers except in special situations. Use systemic antibiotics for individuals with clinical evidence of systemic infection, such as positive blood cultures, cellulitis, fasciitis, osteomyelitis, systemic inflammatory response syndrome (SIRS) or sepsis if consistent with the individual’s goals. Evaluate the individual for osteomyelitis if exposed bone is present; the bone feels rough or soft or the ulcer has failed to heal with prior therapy. ©NPUAP & EPUAP, 2009 42 Biophysical Agents • Consider a course of electrical stimulation for Stage III & IV and recalcitrant Stage II pressure ulcers. (A) • Consider pulsed electromagnetic treatment for recalcitrant Stage II-IV PUs. • Consider NPWT as an early adjuvant for deep, full thickness PUs. (B) ©NPUAP & EPUAP, 2009 43 Biophysical Agents • Consider infrared therapy for recalcitrant full thickness ulcers. • Consider low frequency ultrasound spray for the treatment of clean recalcitrant full thickness PUs and low frequency ultrasound for debridement of soft devitalized tissue. • Consider a course of hydrotherapy & pulsed lavage. • There is insufficient peer reviewed, published evidence to recommend topical oxygen, hyperbaric oxygen, laser or ultraviolet light therapies for the treatment of pressure ulcers. ©NPUAP & EPUAP, 2009 44 Biological Dressings & Growth Factors • Insufficient evidence to support biological dressings • PDGF-BB may improve healing – insufficient evidence to support recommendations. – Lacks FDA approval for pressure ulcers – Approved for diabetic foot ulcers ©NPUAP & EPUAP, 2009 45 Surgery for Pressure Ulcers • • • • • Validate end-of-life decisions if anticipating surgery. Optimize physical & psychological factors that may impair surgical wound healing. Assess for osteomyelitis; if present infected bone must be resected prior to or during surgical closure. (B) Initiate a program of progressive sitting according to surgeon’s orders & position the individual on a pressureredistributing chair cushion. Ensure the individual has a positive social network at home (B) as well as needed equipment, and the ability to maintain the equipment and adhere to postoperative needs. ©NPUAP & EPUAP, 2009 46 PU Management in Individuals Requiring Palliative Care • Dearth of RCTs comparing approaches in human subjects • Impossible to eradicate PrU due to multiple risk factors & co-morbidities • Healing of PU may be unrealistic goal & new ones may occur. • Goals of care to be established in collaboration with individual & family. To the extent possible, allow the individual to direct care. ©NPUAP & EPUAP, 2009 47 PU Management in Individuals Requiring Palliative Care – Risk Assessment • Patient and Risk Assessment • Pressure Redistribution • Nutrition and Hydration • Skin Care • Pain Assessment and Management • Pressure Ulcer Care – Exudate – Odor – Pain ©NPUAP & EPUAP, 2009 48 Guideline Availability (www.npuap.org) EPUAP Free on web* Quick Reference Printed copy Clinical Practice Guideline through NPUAP Printed copy through NPUAP NPUAP Free on web Printed copy from NPUAP website Printed copy from NPUAP website *Translations will be available in multiple languages. ©NPUAP & EPUAP, 2009 84 “Spin-offs” ©NPUAP & EPUAP, 2009 85 Implementation & Dissemination ©NPUAP & EPUAP, 2009 86 The End ©NPUAP & EPUAP, 2009 52