Document 6532880

ASSET™ EZ4-NCO Dry
Sampler for Isocyanates
Providing Ultimate Sensitivity for Vapor Phase and Particulate Isocyanates
Isocyanates are used in the production of polyurethane (PUR) materials, one of the most
widely used plastics in the world. Workers who are exposed to these compounds are at risk
for respiratory disorders, asthma and other health conditions. Particulates form incomplete
reactions with the reagent as well as with the isocyanate monomers and oligomers being
measured, which results in underestimation of exposure.
Isocyanates exposure is frequently underestimated with
other air sampling devices because the particulates form
incomplete reactions with both, the reagents and the
isocyanate compounds.
Features
to achieve low detection limits
• Ability
for both vapor and particulate phase
isocyanates
• Sampling from 5 minutes to > 8 hours
derivatization reactions into stable
• Fast
derivatives
• No field extraction/desorption
• High capacity
• No interferences
special storage requirements before
• No
and after sampling
The ASSET EZ4-NCO sampling device is a unique dry sampler based on derivatization of
isocyanate groups with di-n-butylamine (DBA). The sampler consists of a denuder and a filter,
both impregnated with DBA. The extract is analyzed using LC-MS or LC-MS-MS offering the
ultimate sensitivity and low detection limits not capable with other methods.
Isocyanate
Dibutylamine
Isocyanate dibutylamine derivative
(urea derivative)
Ordering Information
Product Description
Sampling Device
ASSET EZ4-NCO Dry Sampler
Analytical Columns
LC-MS-MS Ascentis® Express C18, 5 cm x 2.1 mm, 2.7 μm particles
LC-MS Ascentis Express C18, 15 cm x 4.6 mm, 2.7 μm particles
Analytical Standard
DBA Isocyanate Mix (acetonitrile:methanol, 99:1, varied conc)
Qty.
Cat. No.
10
50
5027-U
5028-U
1
1
53822-U
53829-U
6 x 1 mL
40141-U
6 x 1 mL
40142-U
2 x 1 mL
40143-U
Isocyanic acid-di-n-butylamine (ICA-DBA) 1 μg/mL
Ethyl isocyanate-di-n-butylamine (EIC-DBA) 1 μg/mL
Hexamethylene diisocyanate-2(di-n-butylamine) (HDI-2(DBA)) 1 μg/mL
Isophorone isocyanate-2(di-n-butyl amine) isomer 1 (IPDI-2(DBA)) 1 μg/mL
Isophorone isocyanate-2(di-n-butyl amine) isomer 2 (IPDI2-2(DBA)) 0.4 μg/mL
4,4’-Methylenediphenyl diisocyanate-2(di-n-butylamine) (4,4’-MDI-2(DBA)) 1 μg/mL
Methyl isocyanate-di-n-butylamine (MIC-DBA) 1 μg/mL
Phenyl isocyanate-di-n-butylamine (PhI-DBA) 1 μg/mL
Propyl isocyanate-di-n-butylamine (PIC-DBA) 1 μg/mL
2,4-Toluene diisocyanate-di-n-butylamine (2,4-TDI-2(DBA)) 1 μg/mL
2,6-Toluene diisocyanate-2(di-n-butylamine) (2,6-TDI-2(DBA)) 1 μg/mL
d9-DBA Isocyanate Internal Standard Mix
Isocyanic acid-di-n-butylamine-d9 (ICA-DBA- d9) 1 μg/mL
Ethyl isocyanate-di-n-butylamine-d9 (EIC-DBA-d9) 1 μg/mL
Hexamethylene diisocyanate-2(di-n-butylamine-d9) (HDI-2(DBA-d9)) 1 μg/mL
Isophorone diisocyanate-2(di-n-butylamine-d9) isomer 1 (IPDI-2(DBA-d9)) 1 μg/mL
Isophorone diisocyanate-2(di-n-butylamine-d9) isomer 2 (IPDI2-2(DBA-d9)) 0.28 μg/mL
4,4-Methylenediphenyl diisocyanate-2(di-n-butylaine-d9) (4,4’-MDI-2(DBA-d9)) 1 μg/mL
Methyl isocyanate-di-n-butylamine-d9 (MIC-DBA-d9) 1 μg/mL
Phenyl isocyanate-di-n-butylamine-d9 (PhI-DBA-d9) 1 μg/mL
Propyl isocyanate-di-n-butylamine-d9 (PIC-DBA-d9) 1 μg/mL
2,4-Toluene diisocyanate-2(di-n-butylamine-d9) (2,4-TDI-2(DBA-d9)) 1 μg/mL
2,6-Toluene diisocyanate-2(di-n-butylamine-d9) (2,6-TDI-2(DBA-d9)) 1 μg/mL
DBA Isocyanate Standard Kit
Includes 1 mL of DBA Isocyanate Mix and 1 mL of d9-DBA Internal Standard Mix
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Analytical Service:
References
Methods:
1. ISO 17734-1:2006, Determination of organonitrogen compounds in air using liquid chromatography and mass
spectrometry — Part 1: Isocyanates using dibutylamine derivatives.
2. ISO 17734-2:2006, Determination of organonitrogen compounds in air using liquid chromatography and mass
spectrometry — Part 2: Amines and aminoisocyanates using dibutylamine and ethyl chloroformate derivatives.
Institutet För Kemisk Analys Norden AB
Esplanadgatan 9
SE-281 38 Hässleholm
Sweden
Contact: Mikael Adamsson
Office: +46-451-655-61
Email: [email protected]
3. In a technical ISO report, the technology is described as the only methodology that covers all situations.
ISO/TR 17737:2007, Workplace air – Guidelines for selecting analytical methods for sampling and analyzing
isocyanates in air.
Publications:
1. Title: Solvent-Free Sampling with Di-n-Butylamine for Monitoring of Isocyanates in Air
Authors: Asa Marand, Daniel Karlsson, Marianne Dalene and Gunnar Skarping
Affiliation: Department of Analytical Chemistry, Work Environment Chemistry, Stockholm University, P.O. Box
460, S-28124 Hassleholm, Sweden
Journal: Journal of Environmental Monitoring, 2005, 7, pg. 335-343
Bureau Veritas
Industrial Hygiene
22345 Roethel Drive
Novi, MI 48375
US Calls: (800) 806-5887
International and US Calls: (248) 344-1770
Fax: (248) 344-2656
[email protected]
2. Title: Determination of Airborne Isocyanates as Di-n-Butylamine Derivatives Using Liquid Chromatography
and Tandem Mass Spectrometry
Authors: Daniel Karlsson, Jakob Dahlin, Asa Marand, Gunnar Skarping and Marianne Dalene
Affiliation: Department of Analytical Chemistry, Work Environment Chemistry, Stockholm University, P.O. Box 460,
S-28124 Hassleholm, Sweden
Journal: Analytica Chimica Acta 534 (2005) 263-269
For more information, visit
sigma-aldrich.com/asset
For more information or if you would like to
become an Analytical Service partner, contact:
Kristen Schultz
Environmental Arena Team Leader
Air Monitoring Product Manager
Phone: (814) 359-5718
[email protected]
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Safety-related Information sigma-aldrich.com/safetycenter
©2012 Sigma-Aldrich Co. LLC. All rights reserved. SIGMA-ALDRICH and SUPELCO are trademarks of Sigma-Aldrich Co. LLC, registered in the US and other countries. ASSET is a trademark of SigmaAldrich Co. LLC. Supelco brand products are sold through Sigma-Aldrich, Inc. Purchaser must determine the suitability of the product(s) for their particular use. Additional terms and conditions may
apply. Please see product information on the Sigma-Aldrich website at www.sigmaaldrich.com and/or on the reverse side of the invoice or packing slip.
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