Prescribable liquid (sip feed) supplements Table A10.1.1 Note
Transcription
Prescribable liquid (sip feed) supplements Table A10.1.1 Note
Table A10.1.1 Prescribable liquid (sip feed) supplements Note: Many sip feed supplements are available in a variety of flavours to offset taste fatigue. Some, but not all, are nutritionally complete; check compositional details before use. Some products can also be used for tube feeding. Product type Standard energy (1 kcal/mL) Juice type (low fat) (1.25–1.5 kcal/mL) High energy (1.5–2.4 kcal/mL) High energy + fibre (1.5–2.0 kcal/mL) High protein (1.0–1.5 kcal/mL) Product name (manufacturer) Quantity Ensure (Abbott) 250 mL Fresubin Original (Fresenius Kabi) 200 mL Ensure Plus Juce (Abbott) 220 mL Fortijuce (Nutricia Clinical) 200 mL Provide Xtra Juice Drink (Fresenius Kabi) 200 mL Resource Fruit (Nestlé) 200 mL Ensure Plus Milkshake style (Abbott) 220 mL Ensure Plus Savoury (Abbott) 220 mL Ensure Plus Yoghurt style (Abbott) 220 mL Ensure Twocal (Abbott) 200 mL Fortisip Bottle (Nutricia Clinical) 200 mL Fortisip Compact (Nutricia Clinical) 125 mL Fortisip Extra (Nutricia Clinical) 200 mL Fortisip Yogurt Style (Nutricia Clinical) 200 mL Fresubin 2 kcal Drink (Fresenius Kabi) 200 mL Fresubin Energy (Fresenius Kabi) 200 mL Renilon 7.5 (Nutricia Clinical) 125 mL Ensure Plus Fibre (Abbott) 200 mL Fresubin 2 kcal Fibre Drink (Fresenius Kabi) 200 mL Fresubin Energy Fibre (Fresenius Kabi) 200 mL Fortisip Compact Fibre (Nutricia Clinical) 125 mL Fortisip Multi Fibre (Nutricia Clinical) 200 mL Resource 2.0 Fibre (Nestlé) 200 mL Fortimel Regular (Nutricia Clinical) 200 mL Fresubin Protein Energy Drink (Fresenius Kabi) 200 mL Resource Protein (Nestlé) 200 mL Per bottle/can kJ kcal Protein (g) Fibre (g) 1058 251 10.0 0.0 840 200 7.6 0.0 1404 330 10.6 0.0 1280 300 8.0 0.0 1260 250 7.5 0.0 1040 250 8.0 0.0 1390 330 13.8 0.0 1390 330 14.0 0.0 1390 330 13.8 0.0 1675 400 16.8 2.0 1260 300 12.0 0.0 1250 300 12.0 0.0 1350 320 20.0 0.0 1260 300 12.0 0.4 1680 400 20.0 0.0 1260 300 11.2 0.0 1050 250 9.4 0.0 1284 300 13.0 5.0 1680 400 20 3.2 1260 300 11.2 4.0 1250 300 11.8 4.5 1260 300 12.0 4.6 1672 400 18.0 5.0 840 200 20.0 0.0 1260 300 20.0 0.0 1060 250 18.8 0.0 (Continued) Manual of Dietetic Practice, Fifth Edition. Edited by Joan Gandy. © 2014 The British Dietetic Association. Published 2014 by John Wiley & Sons, Ltd. Companion Website: www.manualofdieteticpractice.com Table A10.1.1 (Continued) Product type Thickened (1.5–2.4 kcal/mL) Powdered Product name (manufacturer) Quantity Per bottle/can Fresubin Thickened (Fresenius Kabi) 200 mL Syrup (stage 1) and custard (stage 2) Nutilis Complete Stage 1 (Nutricia) 125 mL Resource Thickened Drink (Nestlé) 114 mL Syrup and custard consistencies SLO Drinks (SLO Drinks) Syrup, custard and pudding consistencies Thick & Easy Thickened Juices (Fresubin Kabi) 118-mL pot or 1.42-L bottle Custard consistency Complan Shake In 250 mL of water (Complan Foods) In 200 mL of whole milk 57-g sachet Foodlink Complete (Foodlink) 3 heaped tablespoonfuls in 250 mL of water Foodlink Complete with Fibre (Foodlink) 4 heaped tablespoonfuls in 250 mL of water Oral Impact (Nestlé) 74 g in 250 mL of water Vegenat-med Balanced Protein (Vegenat) 110-g sachet Vegenat-med High Protein (Vegenat) 110-g sachet kJ kcal Protein (g) Fibre (g) 1260 300 20.0 * 1263 300 12.0 4.0 435 103 0.0 0.0 * * * * * * 1057 1621 251 387 8.8 15.6 0.0 0.0 1048 249* 12.5* 0.0 1137 270 12.3 5.0 * * * 1924 458 18.0 5.8 1940 463 23.3 6.0 *Exact composition varies – see manufacturer’s data. Table A10.1.2 Non-prescribable liquid supplements These products can be purchased by patients from supermarkets and chemists, and are useful at times when dietary intake is poor. None is nutritionally complete. Product name (manufacturer) Quantity Per sachet + 200 mL of whole milk kJ kcal Protein (g) Fibre (g) Build-Up Nutrition Shake (Nestlé) 38-g sachet in 200 mL of whole milk Complan (Complan Foods) 57-g sachet in 200 mL of whole milk 1105 263 14.9 3.0 1596 380 14.9 0.2 Table A10.1.3 Prescribable solid/semi solid supplements Dessert style – also useful for dysphagic patients. Product type Solid/semi solid desserts Product name (manufacturer) Quantity Per bottle/can kJ kcal Protein (g) Fibre (g) Clinutren Dessert (Nestlé) 125 g Ensure Plus Crème (Abbott) 125 g Forticreme Complete (Nutricia Clinical) 125 g Fortisip Fruit Dessert (Nutricia Clinical) 150 g Fresubin Crème (Fresenius Kabi) 125 g Resource Dessert Energy (Nestlé) 125 g Resource Dessert Fruit (Nestlé) 125 g 650 156 11.9 0.0 718 171 7.1 0.0 844 200 11.9 0.0 840 200 10.5 3.9 945 225 12.5 2.5 839 200 6.0 0.0 848 200 6.3 1.8 Table A10.1.4 Single nutrient component supplements Component Product name (manufacturer) Notes, ACBS indications and nutritional values Carbohydrate Caloreen (Nestlé) Powder Maxijul Liquid (SHS) Liquid Maxijul Super Soluble (SHS) Powder Polycal (Nutricia Clinical) Powder Polycal Liquid (Nutricia Clinical) Liquid Resource Optifibre (Nestlé) Powder S.O.S. 10, 15, 20, 25 (Vitaflo) Powder Vitajoule (Vitaflo) Powder Calogen (Nutricia Clinical) Liquid (100% LCTs fat emulsion) Fresubin 5kcal Shot (Fresenius Kabi) Liquid Liquigen (SHS) Liquid (97% MCTs) Medium-Chain Triglyceride (MCT) Oil (SHS) Liquid (100% MCTs) 1640 kJ (390 kcal)/100 g Casilan 90 (Heinz) Powder (90% protein) Protifar (Nutricia Clinical) Powder (89% protein) Vitapro (Vitaflo) Powder (75% protein) 1572 kJ (370 kcal)/100 g Fat Protein 850 kJ (200 kcal)/100 mL 1615 kJ (380 kcal)/100 g Disease related malnutrition or malabsorption states or other conditions requiring fortification with a high or readily available carbohydrate supplement 1630 kJ (384 kcal)/100 g 1050 kJ (247 kcal)/100 mL 323 kJ (76 kcal) and 78 g of fibre/100 g 1590 kJ (380 kcal)/100 g 1610 kJ (380 kcal)/100 g 1850 kJ (450 kcal)/100 mL 2100 kJ (500 kcal)100 mL 1850 kJ (450 kcal)/100 mL 3515 kJ (855 kcal)/100 mL 1580 kJ (373 kcal)/100 g 1506 kJ (360 kcal)/100 g LCTs, long chain triglycerides; MCTs, medium chain triglycerides. Disease related malnutrition or malabsorption states or other conditions requiring fortification with a high fat supplement Steatorrhoea associated with cystic fibrosis (pancreas), intestinal lymphangiectasia, intestinal surgery, chronic liver disease/ cirrhosis and other proven malabsorption syndromes Disease related malnutrition or malabsorption states or other conditions requiring fortification with a high protein supplement Protein energy malnutrition or malabsorption states, hypoproteinaemia and as a protein source in modular feed Table A10.1.5 Multiple nutrient component supplements Components Product name (manufacturer) Notes, ACBS indications and nutritional values Fat/ carbohydrate MCT Duocal (SHS) Powder Protein/ carbohydrate Duocal (SHS) Liquid ProSource (Nutrinovo) Liquid Protein/fat/ carbohydrate Calogen Extra (Nutricia Clinical) Liquid Calshake (Fresenius Kabi) Powder Conditions requiring extra calories, e.g. fat malabsorption or where assimilation of LCTs is impaired Conditions requiring extra calories Protein energy malnutrition and patients on a fluid restricted diet High energy fat emulsion with protein, carbohydrate, vitamins and minerals For increased energy requirements, e.g. patients with cystic fibrosis, cancer or HIV/AIDS High energy, high protein drink for patients with involuntary weight loss Disease related malnutrition or malabsorption states and other conditions requiring fortification with energy and protein, e.g. burns Enshake (Abbott) Powder Pro-Cal (Vitaflo) Powder Pro-Cal Shot (Vitaflo) Liquid QuickCal (Vitaflo) Powder Scandishake Mix (Nutricia Clinical) Powder Vitasavoury 200 (Vitaflo) Powder Vitasavoury 300 (Vitaflo) Powder High energy supplement for disease related malnutrition based on skimmed milk powder, carbohydrate and fat Low volume, high energy supplements for disease related malnutrition or malabsorption states or other conditions requiring additional energy and protein 50 g in 150 mL of water provides 1041 kJ (249 kcal), 36 g of CHO and 11.6 g of fat Per 100 mL: 695 kJ (166 kcal), 23.7 g of CHO and 7.9 g of fat (30% MCTs) Per 30 mL: 420 kJ (100 kcal), 10 g of protein and 15 g of CHO Per 100 mL: 1650 kJ (400 kcal), 5.0 g of protein, 4.5 g of CHO and 40.3 g of fat 87-g sachet + 240 mL of whole milk provides approx. 2495 kJ (596 kcal), 11.6 g of protein, 68.4 g of CHO and 30.8 g of fat 96.5-g sachet + 240 mL of whole milk provides approx. 2519 kJ (600 kcal), 16 g of protein, 78.4 g of CHO and 24.7 g of fat 15-g sachet provides 418 kJ (/100 kcal), 2 g of protein, 4 g of CHO and 8.4 g of fat Per 30 mL: 418 kJ (/100 kcal), 2 g of protein, 4 g of CHO and 8.5 g of fat 13-g sachet provides 418 kJ (100 kcal), 0.6 g of protein, 2.2 g of CHO and 10 g of fat 85-g sachet + 240 mL of whole milk provides 2457 kJ (588 kcal), 11.7 g of protein, 66.8 g of CHO and 30.4 g of fat 33-g sachet provides 855 kJ (200 kcal), 4 g of protein, 7.4 g of CHO and 17.2 g of fat 50-g sachet provides 1295 kJ (300 kcal), 6 g of protein, 11.3 g of CHO and 26.0 g of fat CHO, carbohydrate; MCTs, medium chain triglycerides; LCTs, long chain triglycerides. Table A10.1.6 Food and fluid thickeners For thickening of food and drinks of patients with dysphagia. Type of product Product name (manufacturer) Modified maize starch powder* Multi Thick (Abbott) Nutilis (Nutricia Clinical) Resource ThickenUp (Nestlé) Thick and Easy (Fresenius Kabi) Thixo-D (Sutherland) Vitaquick (Vitaflo) Resource ThickenUp Clear (Nestlé) Maltodextrin and xanthan gum *See individual manufacturer’s recommendations for the quantities required to achieve various textures. Table A10.1.7 Enteral feeds – standard indications Product type Standard energy (1 kcal/mL) Nutritionally complete (1.0–1.2 kcal/mL) Medium energy (1.2–1.3 kcal/mL) High energy (1.5–2.0 kcal/mL) Product name (manufacturer) Per 100 mL Fresubin Original (Fresenius Kabi) Fresubin Original Fibre (Fresenius Kabi) Isosource Fibre (Nestlé) Isosource Standard (Nestlé) Jevity (Abbott) Jevity Promote (Abbott) Novasource GI Control (Nestlé) 40% MCTs Nutrison (Nutricia Clinical) Nutrison MCT (Nutricia Clinical) 61% MCTs Nutrison Multi Fibre (Nutricia Clinical) Osmolite (Abbott) Fresubin 1000 Complete (Fresenius Kabi) Complete in 1000 mL Fresubin 1200 Complete (Fresenius Kabi) Complete in 1000 mL Fresubin 1800 Complete (Fresenius Kabi) Complete in 1500 mL Fresubin 2250 Complete (Fresenius Kabi) Complete in 1500 mL Nutrison 1000 Complete Multi Fibre (Nutricia Clinical) Complete in 1000 mL Nutrison 1200 Complete Multi Fibre (Nutricia Clinical) Complete in 1000 mL Jevity Plus (Abbott) Jevity Plus HP (Abbott) Nutrison Protein Plus (Nutricia Clinical) Nutrison Protein Plus Multi Fibre (Nutricia Clinical) Osmolite Plus (Abbott) Ensure Twocal (Abbott) Fresubin Energy (Fresenius Kabi) Fresubin Energy Fibre (Fresenius Kabi) Fresubin HP Energy (Fresenius Kabi) Isosource Energy (Nestlé) Isosource Energy Fibre (Nestlé) Jevity 1.5 kcal (Abbott) Novasource GI Forte (Nestlé) Nutrison Energy (Nutricia Clinical) Nutrison Energy Multi Fibre (Nutricia Clinical) Osmolite 1.5 kcal (Abbott) Resource Energy (Nestlé) kJ kcal Protein (g) Fibre (g) 420 420 422 420 441 427 444 100 100 100 100 106 101 106 3.8 3.8 3.8 4.0 4.0 5.6 4.1 0.0 2.0 1.4 0.0 1.8 1.7 2.2 420 420 100 100 4.0 5.0 0.0 0.0 420 424 420 500 500 630 420 100 100 100 120 120 150 100 4.0 4.0 5.5 6.0 6.0 5.6 5.5 1.5 0.0 2.0 2.0 2.0 2.0 2.0 505 120 5.5 2.0 504 547 525 525 508 838 630 630 630 670 630 640 631 630 630 632 630 120 130 125 125 121 200 150 150 150 160 150 152 150 150 150 150 150 5.5 8.1 6.3 6.3 5.6 8.4 5.6 5.6 7.5 5.7 4.9 6.4 6.0 6.0 6.0 6.3 5.6 2.2 1.5 0.0 1.5 0.0 1.0 0.0 2.0 0.0 0.0 1.5 2.2 2.2 0.0 1.5 0.0 <0.5 MCTs, medium chain triglycerides. Table A10.1.8 Specialist indication enteral feeds and supplements Product type Amino acid liquid formula Low sodium liquid formula Peptide based liquid formula Soya protein liquid formula Product name (manufacturer) Elemental 028 Extra (SHS) Sip feed Nutrison Low Sodium (Nutricia Clinical) Peptamen (Nestlé) Peptamen HN (Nestlé) Peptisorb (Nutricia Clinical) Perative (Abbott) Survimed OPD (Fresenius Kabi) Fresubin Soya Fibre (Fresenius Kabi) Nutrison Soya (Nutricia Clinical) Nutrison Soya Multi Fibre (Nutricia Clinical) Per 100 mL kJ kcal Protein (g) Fibre (g) 360 86 2.5 0.0 420 420 556 425 552 420 420 420 420 100 100 133 100 131 100 100 100 100 4.0 4.0 6.6 4.0 6.7 4.5 3.8 4.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 1.5 Table A10.1.9 Specialised formulae for specific clinical conditions Condition Product (manufacturer) Notes and ACBS indications Cancer Forticare (Nutricia Clinical) Liquid Supportan (Fresenius Kabi) Liquid ProSure (Abbott) Liquid Alicalm (SHS) Powder Modulen IBD (Nestlé) Powder Can be flavoured with Flavour Mix (Nestlé) Powder KetoCal (SHS) Powder Pancreatic cancer Lung cancer undergoing chemotherapy Generaid (SHS) Powder Oxepa (Abbott) Liquid Pulmocare (Abbott) Liquid Respifor (Nutricia Clinical) Liquid Nepro (Abbott) Liquid Whey protein + BCAA Chronic liver disease and/or portohepatic encephalopathy Acute lung injury, ARDS and SIRS Crohn’s disease Epilepsy Liver disease Pulmonary disease Renal disease Renal/liver disease Short bowel syndrome Synthetic diets Renamil (KoRa) Powder Renapro (KoRa) Powder Duocal Super Soluble (SHS) Powder Suplena (Abbott) Liquid Elemental 028 Extra (SHS) Powder Metabolic Mineral Mixture (SHS) Powder Pancreatic cancer Contains EPA Crohn’s disease Active Crohn’s disease/nutritional support during Crohn’s remission Part of ketogenic diet in management of drug therapy resistant epilepsy COPD, cystic fibrosis or respiratory failure Disease related malnutrition in COPD + BMI <20 kg/m2 Chronic renal failure with haemodialysis or continuous ambulatory peritoneal dialysis Cirrhosis Chronic renal failure Biochemically proven hypoproteinaemia Patients on dialysis For use where a high energy, low fluid and low electrolyte diet is required Chronic/acute renal failure without dialysis Chronic/acute liver disease with fluid restriction Intractable malabsorption and proven irritable bowel disease Mineral and trace element supplement for synthetic diets ARDS, acute respiratory distress syndrome; BCAA, branched chain amino acids; COPD, chronic obstructive pulmonary disease; SIRS, systemic inflammatory response syndrome; BMI, body mass index; EPA, eicosapentaenoic acid. Table A10.1.10 Nutritional supplements for metabolic diseases Condition Product (manufacturer) Notes and ACBS indications Glutaric aciduria XLYS, TRY Glutaridon* (SHS) Powder Glycosade (Vitaflo) Powder HCU cooler (Vitaflo) Liquid HCU Express (Vitaflo) Powder HCU LV (SHS) Powder XMET Homidon* (SHS) Powder XMET Maxamum (SHS) Powder XLEU Faladon (SHS) Powder Isoleucine Amino Acid Supplement (Vitaflo) Powder Valine Amino Acid Supplement (Vitaflo) Powder MSUD Aid III (SHS) Powder MSUD cooler (Vitaflo) Liquid MSUD express (Vitaflo) Powder MSUD Maxamum (SHS) Powder XMTVI Asadon (SHS) Powder XMTVI Maxamum (SHS) Powder Cystine Amino Acid Supplement (Vitaflo) Powder Leucine Amino Acid Supplement (Vitaflo) Powder Phenylalanine Amino Acid Supplement (Vitaflo) Powder DocOmega (Vitaflo) Powder KeyOmega (Vitaflo) Powder Add-Ins (SHS) Powder Easiphen (SHS) Liquid Lophlex (SHS) Powder L-Tyrosine (SHS) Powder Milupa PKU 3-advanta (Milupa) Powder Phlexy-10 Exchange System (SHS) Capsule/tablet/drink PK Aid-4 (SHS) Powder Type 1 glutaric aciduria Glycogen storage diseases Homocystinuria Hypermethioninaemia Hypermethioninaemia or homocystinuria Isovaleric acidaemia Maple syrup urine disease Methylmalonic acidaemia Propionic acidaemia Other errors of protein metabolism Other inborn errors of metabolism Phenylketonuria (PKU) Plus other metabolic conditions where a constant glucose supply is essential Methionine free protein substitute And vitamin B6 non-responsive homocystinuria Essential and non-essential amino acids except methionine Essential and non-essential amino acids except leucine Use in low protein diets by mixing with protein substitute, adding to modular feeds, or incorporating into other permitted food or drink Essential and non-essential amino acids except isoleucine, leucine and valine Essential and non-essential amino acids except methionine, threonine, valine and low isoleucine Use in low protein diets by mixing with protein substitute, adding to modular feeds, or incorporating into other permitted food or drink n-3 supplement containing DHA n-3 and supplement containing AA and DHA Phenylalanine free protein substitute Ready to drink phenylalanine free liquid product Phenylalanine free drink mix For use in maternal PKU where there are low plasma tyrosine concentrations Phenylalanine free protein supplement Each unit (1 sachet, 10 tablets or 20 capsules) provides 10 g of amino acids except phenylalanine Unflavoured blend of essential and non-essential amino acids (Continued) Table A10.1.10 (Continued) Condition Tyrosinaemia Urea cycle disorders Low protein milk replacement drinks Vitamin and mineral component Flavouring preparations Product (manufacturer) Notes and ACBS indications PKU cooler10 (Vitaflo) Liquid Provides 10 g of protein equivalent PKU cooler15 (Vitaflo) Liquid Provides 15 g of protein equivalent PKU cooler20 (Vitaflo) Liquid Provides 20 g of protein equivalent PKU express (Vitaflo) powder 1 × 25 g sachet provides 15 g of protein equivalent PKU Lophlex LQ 10 (SHS) Liquid Provides 10 g of protein equivalent PKU Lophlex LQ 20 (SHS) Liquid Provides 20 g of protein equivalent Tyrosine Amino Acid Supplement (Vitaflo) Powder XP Maxamum (SHS) Powder TYR cooler (Vitaflo) Liquid TYR express (Vitaflo) powder 25-g sachet provides 15 g of protein equivalent XPHEN TYR Tyrosidon (SHS) Powder XPTM Tyrosidon (SHS) Powder L-Arginine (SHS) Powder Dialamine (SHS) Powder EAA Supplement (Vitaflo) Powder Loprofin PKU Drink (SHS) Liquid Milupa lp-drink (Milupa) Powder ProZero (Vitaflo) Liquid Sno-Pro (SHS) Liquid Phlexy-Vits (SHS) Powder/tablet FlavourPac (Vitaflo) Powder Blackcurrant, lemon, orange, tropical, raspberry Modjul Flavour System (SHS) Powder Blackcurrant, orange, pineapple Ready to drink phenylalanine free protein substitutes, including n-3 LCPs, DHA and EPA Phenylalanine free protein substitute Phenylalanine free liquid containing a balanced mixture of essential and non-essential amino acids, carbohydrates, vitamins, trace elements and some minerals For use in low protein diets Phenylalanine free protein substitute drink mix Ready to drink tyrosine and phenylalanine free protein substitute Unflavoured, powdered tyrosine and phenylalanine free protein substitute Normal plasma methionine concentrations Above normal plasma methionine concentrations Except arginase deficiency Essential amino acid supplement Low protein, low phenylalanine drink based on cow’s milk Suitable for dietary management of amino acid metabolism disorders Liquid blend of carbohydrate and fat Low protein, low phenylalanine drink based on milk extracts For use with restricted diets for PKU and similar amino acid abnormalities For use with unflavoured protein substitutes *A source of vitamins, minerals and trace elements is also required, e.g. Phlexy-Vits. AA, arachidonic acid; DHA, docosahexaenoic acid; EPA, eicosapentanoic acid; LCPs, long chain polyunsaturated fatty acids. Table A10.1.11 Manufacturers’ websites Abbott, Abbott Laboratories Ltd Complan Foods, Complan Foods Ltd Foodlink, Foodlink (UK) Ltd Fresenius Kabi, Fresenius Kabi Ltd Heinz, H. J. Heinz Company Ltd KoRa, KoRa Healthcare Ltd Milupa, Milupa Aptamil Nestlé, Nestlé Nutrition Nutricia Clinical, Nutricia Clinical Care Nutrinovo, Nutrinovo Ltd SHS, SHS International Ltd SLO Drinks, SLO Drinks Ltd Sutherland, Sutherland Health Ltd Vegenat, Vegenat Vitaflo, Vitaflo International Ltd www.abbott.co.uk www.complanfoods.com www.foodlinkltd.co.uk www.fresenius-kabi.co.uk/ www.heinz.co.uk www.kora-health.com/ www.milupa-metabolics.com www.nestlenutrition.com www.nutricia.co.uk www.nutrinovo.com www.shs-nutrition.com www.slodrinks.com www.sutherlandhealth.com www.vegenat.es/e_default.asp www.vitaflo.co.uk Table A10.2.1 Paediatric sip feeds Product type Product name (manufacturer) Per 100 mL of ready to drink product/standard dilution kJ Low energy (<1 kcal/mL) Standard energy (1 kcal/mL) kcal Protein (g) Fibre (g) Nutriprem 1 (Cow & Gate) Liquid 201 48 1.5 0.5 Nutriprem 2 (Cow & Gate) Liquid SMA Gold Prem 2 (SMA Nutrition) Powder SMA High Energy (SMA Nutrition) Liquid 310 75 2.0 0.6 305 73 1.9 0.0 382 91 2.0 0.0 Clinutren Junior (Nestlé) Powder Infatrini (Nutricia Clinical) Liquid 420 100 3.0 0.0 415 100 2.6 0.8 Paediasure (Abbott) Liquid Paediasure Fibre (Abbott) Liquid Paediasure Peptide (Abbott) Liquid Similac High Energy (Abbott) Liquid 422 100 2.8 0.0 420 100 2.8 0.8 420 100 3.0 0.0 419 100 2.6 0.4 Notes 60-mL bottle, formula for low birth weight babies <1.8 kg only available in hospital Catch-up growth in preterm infants (<35 weeks’ gestation at birth) and small for gestational age infants up to 6 months corrected age 250-mL carton, disease related malnutrition, malabsorption, growth failure from birth to 18 months Growth failure*† 100-mL bottle, failure to thrive, disease related malnutrition and malabsorption, from birth up to body weight of 8 kg 200-mL bottle*† 120-mL bottle, increased energy requirements, faltering growth and/or need for fluid restriction, body weight up to 8 kg (Continued) Table A10.2.1 (Continued) Product type High energy (1.5 kcal/mL) Product name (manufacturer) Fortini (Nutricia Clinical) Liquid Fortini Multifibre (Nutricia Clinical) Liquid Fortini Smoothie Multifibre (Nutricia Clinical) Liquid Frebini Energy Drink (Fresenius Kabi) Liquid Frebini Energy Fibre Drink (Fresenius Kabi) Liquid Paediasure Plus (Abbott) Liquid Paediasure Plus Fibre (Abbott) Liquid Paediasure Plus Juce (Abbott) Liquid Resource Junior (Nestlé) Liquid Per 100 mL of ready to drink product/standard dilution Notes kJ kcal Protein (g) Fibre (g) 630 150 3.4 0.0 630 150 3.4 1.5 625 150 3.4 1.4 630 150 3.8 0.0 630 150 3.8 1.1 Disease related malnutrition and growth failure in children aged 1–10 years,* body weight 8–30 kg 632 151 4.2 0.0 *† 626 150 4.2 1.1 *† 638 150 4.2 0.0 Low fat*† 630 150 3.0 0.0 For children aged 1–10 years* Disease related malnutrition and growth failure in children aged 1–6 years,* body weight 8–20 kg *Not suitable for use in children under 1 year of age. †For children aged 1–10 years, body weight 8–30 kg. Table A10.2.2 Feed thickener Product name (manufacturer) Notes Carobel Instant (Cow & Gate) Instant thickening agent, prepared from carob seed flour, suitable from birth. Prescribable for thickening feeds in the treatment of habitual and recurrent vomiting Table A10.2.3 Paediatric enteral feeds – standard indications Product type Product name (manufacturer) Per 100 mL kJ kcal Notes Protein (g) Fibre (g) Low energy (<1 kcal/mL) Nutrini Low Energy Multi Fibre (Nutricia Clinical) Liquid 315 75 2.1 0.8 Standard energy (1 kcal/mL) Clinutren Junior (Nestlé) Powder Frebini Original (Fresenius Kabi) Liquid Frebini Original Fibre (Fresenius Kabi) Liquid Infatrini (Nutricia Clinical) Liquid 420 100 3.0 0.0 420 100 2.5 0.0 420 100 2.5 0.8 415 100 2.6 0.8 Nutrini (Nutricia Clinical) Liquid Nutrini Multi Fibre (Nutricia Clinical) Liquid Paediasure (Abbott) Liquid Paediasure Fibre (Abbott) Liquid Similac High Energy (Abbott) Liquid 420 100 2.8 0.0 420 100 2.8 0.8 Failure to thrive, disease related malnutrition and malabsorption, from birth up to body weight 8 kg For growth failure in children aged 1–6 years, body weight 8–20 kg* 422 100 2.8 0.0 *† 420 100 2.8 0.8 419 100 2.6 0.4 Tentrini (Nutricia Clinical) Liquid Tentrini Multi Fibre (Nutricia Clinical) Liquid Isosource Junior (Nestlé) Liquid 420 100 3.3 0.0 420 100 3.3 1.1 512 122 2.7 0.0 Frebini Energy (Fresenius Kabi) Liquid Frebini Energy Fibre (Fresenius Kabi) Liquid Nutrini Energy (Nutricia Clinical) Liquid 630 150 3.8 0.0 630 150 3.8 1.1 630 150 4.1 0.0 Nutrini Energy Multi Fibre (Nutricia Clinical) Liquid) 630 150 4.1 0.8 Paediasure Plus (Abbott) Liquid Paediasure Plus Fibre (Abbott) Liquid Tentrini Energy (Nutricia Clinical) Liquid 632 151 4.2 0.0 626 150 4.2 1.1 630 150 4.9 0.0 Tentrini Energy Multi Fibre (Nutricia Clinical) Liquid 630 150 4.9 1.1 Medium energy (1.2 kcal/mL) High energy (1.5 kcal/mL) *Not suitable for use in children under 1 year of age. †For children aged 1–10 years, body weight 8–30 kg. For children aged 1–6 years, except bowel fistula, body weight 8–20 kg For growth failure*† Increased energy requirements, faltering growth and/or need for fluid restriction, body weight up to 8 kg For growth failure in children aged 7–12 years, body weight 21–45 kg For growth failure in children aged 1–6 years, body weight 8–20 kg* For growth failure in children aged 1–10 years, body weight 8–30 kg* For growth failure in children aged 1–6 years, body weight 8–20 kg* For children aged 1–6 years, body weight 8–20 kg* and total gastrectomy, not with bowel fistula *† For growth failure in children aged 7–12 years, body weight 21–45 kg For children aged 7–12 years, body weight 21–45 kg and proven inflammatory bowel disease Table A10.2.4 Specialist paediatric formulae Formula type Product name (manufacturer) Per 100 mL of ready to drink product (standard dilution) kJ Amino acid based Fructose based Hydrolysate Low calcium kcal Protein (g) Fibre (g) Emsogen (SHS) Powder 368 88 2.5 0.0 Neocate Active (SHS) Powder Neocate Advance (SHS) Powder Neocate LCP (SHS) Powder Nutramigen AA (Mead Johnson) Powder Galactomin 19 (SHS) Powder Aptamil Pepti 1 (Allergy) (Milupa) Powder 418 100 2.8 0.0 420 100 2.5 0.0 293 70 1.9 0.0 286 68 4.9 0.0 288 69 1.9 0.0 280 67 1.6 0.6 Aptamil Pepti 2 (Allergy) (Milupa) Powder 285 68 1.6 0.6 Cow & Gate Pepti-Junior (Cow & Gate) Powder 275 66 1.8 0.0 Nutramigen Lipil 1 (Mead Johnson) Powder 280 68 1.9 0.0 Nutramigen Lipil 2 (Mead Johnson) Powder 285 68 1.7 0.0 Nutrini Peptisorb (Nutricia Clinical) Liquid Pepdite (SHS) Powder Pepdite 1+ (SHS) Powder 420 100 2.8 0.0 297 71 2.1 0.0 423 100 3.1 0.0 Peptamen Junior (Nestlé) Liquid 420 100 3.0 0.0 Pregestimil Lipil (Mead Johnson) Powder 280 68 1.9 0.0 Locasol (SHS) Powder 278 66 1.9 0.0 Notes Short bowel syndrome, intractable malabsorption, proven inflammatory bowel disease, bowel fistula. Not suitable as sole source of nutrition for children aged 1–5 years* For children aged 1–12 years* ‡ Conditions of glucose plus galactose intolerance Established cow’s milk protein intolerance with or without secondary lactose intolerance‡ Established cow’s milk protein allergy or intolerance. Not suitable for children aged <6 months; suitable for children aged 6 months–12 years Disaccharide and/or whole protein intolerance, or where amino acids and peptides are indicated in conjunction with MCTs‡ Disaccharide and/or whole protein intolerance where additional MCTs are not indicated‡ Established disaccharide and/or whole protein intolerance where additional MCTs are not indicated. Not suitable for children aged <6 months; suitable for children aged 6 months–12 years For growth failure in children aged 1–6 years,* body weight 8–20 kg Disaccharide and/or whole protein intolerance‡ Disaccharide and/or whole protein intolerance, or where amino acids or peptides are indicated in conjunction with MCTs. For children aged 1–12 years* Short bowel syndrome, intractable malabsorption, proven inflammatory bowel disease, bowel fistula, in children aged 1–10 years* Disaccharide and/or whole protein intolerance, or where amino acids or peptides are indicated in conjunction with MCTs and hydrolysed casein‡ Conditions of calcium intolerance requiring restriction of calcium and vitamin D intake‡ Table A10.2.4 (Continued) Formula type Product name (manufacturer) Per 100 mL of ready to drink product (standard dilution) kJ MCT enhanced Caprilon (SHS) Powder MCT Pepdite (SHS) Powder MCT Pepdite +1 (SHS) Powder Monogen (SHS) Powder kcal Protein (g) Fibre (g) Notes 277 66 1.5 0.0 Fat 3.6 g (MCTs 75%)d‡ 286 68 2.0 0.0 Fat 2.7 g, (MCTs 75%)d‡ 381 91 2.8 0.0 313 74 2.0 0.0 Fat 3.6 g, (MCTs 75%)d for children aged 1–12 years* LCAD , CPTD, and primary and secondary lipoprotein lipase deficiency. Fat 2.1 g (MCTs 90%)‡ *† Peptidebased Paediasure Peptide (Abbott) Liquid Peptamen Junior (Nestlé) Liquid 420 100 3.0 0.0 420 100 3.0 0.0 Prethickened infant feeds Residual lactose Enfamil AR (Mead Johnson) Powder SMA Staydown (SMA Nutrition) Powder Enfamil O-Lac (Mead Johnson) Powder Galactomin 17 (SHS) Powder 285 68 1.7 0.0 279 67 1.6 0.0 280 68 1.4 0.0 Proven lactose intolerance‡ 295 70 1.7 0.0 SMA LF (SMA Nutrition) Powder InfaSoy (Cow & Gate) Powder SMA Wysoy (SMA Nutrition) Powder 281 67 1.5 0.0 Proven lactose intolerance in preschool children, galactosaemia and galactokinase deficiency‡ Proven lactose intolerance‡ 275 66 1.6 0.0 280 66 1.8 0.0 Soya based Short bowel syndrome, intractable malabsorption, proven inflammatory bowel disease, bowel fistula*† Significant gastro-oesophageal reflux‡ Proven lactose and associated sucrose intolerance in preschool children, galactokinase deficiency, galactosaemia and proven whole cow’s milk sensitivity‡ *Not suitable for use in children under 1 year of age. †For children aged 1–10 years, body weight 8–30 kg. ‡Suitable from birth to 12 years of age. d Disorders in which a high intake of MCTs is beneficial (MCTs 75%). MCT, medium chain triglycerides; LCAD, long chain acyl-CoA deficiency; CPTD, carnitine palmitoyl transferase deficiency. Table A10.2.5 Nutritional supplements for metabolic diseases (products in italics are also listed in the adult Appendix A10.1) Metabolic disease Product name (manufacturer) Age range Notes Glutaric aciduria (type 1) GA1 Anamix Infant (SHS) Powder GA Gel (Vitaflo) Gel XLYS, Low TRY, Maxamaid (SHS) Powder Glycosade (Vitaflo) Powder Cystine Amino Acid Supplement (Vitaflo) Powder HCU cooler (Vitaflo) Liquid HCU Express (Vitaflo) Liquid HCU gel (Vitaflo) Powder XMET Homidon (SHS) Powder XMET Maxamaid (SHS) Powder XMET Maxamum (SHS) Powder HCU Anamix Infant (SHS) Powder Birth–3 years Contains vitamins, minerals, trace elements, essential and non-essential amino acids except lysine and low tryptophan HCU LV (SHS) Powder Energivit (SHS) Powder >8 years HYPER LYS Anamix Infant (SHS) Powder XLYS Maxamaid (SHS) Powder IVA Anamix Infant (SHS) Powder XLEU Faladon (SHS) Powder Birth–3 years XLEU Maxamaid (SHS) Powder Loprofin PKU Drink (SHS) Liquid Low protein drink (Milupa) Powder Milupa lp-drink (Milupa) Powder ProZero (Vitaflo) Liquid Sno-Pro (SHS) Liquid 1–8 years Glycogen storage disease Homocystinuria Hypermethioninaemia or homocystinuria High energy fat/carbohydrate supplement Hyperlysinaemia Isovaleric acidaemia Low protein milk replacement drinks 1–10 years 1–8 years >2 years Also other metabolic conditions where a constant glucose supply is essential >1 year >3 years >8 years Methionine free protein substitutes for use as nutritional supplements 1–10 years 1–8 years >8 years Birth–3 years 1–8 years Birth–3 years >1 year >1 year >1 year >6 months Methionine free, unflavoured, powdered drink mixes Methionine free, unflavoured, powdered drink mix with vitamins, minerals and trace elements Essential and non-essential amino acids except methionine for proven vitamin B6 non-responsive homocystinuria or hypermethioninaemia For hypermethioninaemia or vitamin B6 nonresponsive homocystinuria For children requiring additional energy, vitamins, minerals and trace elements following a protein restricted diet Essential and non-essential amino acids except lysine Isovaleric acidaemia and other proven disorders of leucine metabolism XLEU Faladon can be used as part of a modular feed or added as an amino acid supplement to XLEU Analog in the latter stages of weaning Low protein, low phenylalanine drink based on cow’s milk for use in PKU For inborn errors of amino acid metabolism For dietary management of amino acid metabolism disorders Liquid blend of carbohydrate and fat Low protein, low phenylalanine drink based on milk extracts for PKU, chronic renal failure and other inborn errors of amino acid metabolism Table A10.2.5 (Continued) Metabolic disease Product name (manufacturer) Maple syrup urine disease MSUD Aid III (SHS) Powder MSUD Anamix Infant (SHS) Powder MSUD Anamix Junior (SHS) Powder MSUD Anamix Junior LQ (SHS) Liquid MSUD cooler (Vitaflo) Liquid MSUD express (Vitaflo) Powder MSUD Gel (Vitaflo) Powder MSUD Maxamaid (SHS) Powder MSUD Maxamum (SHS) Powder MMA/PA Anamix Infant (SHS) Powder XMTVI Asadon (SHS) Powder XMTVI Maxamaid (SHS) Powder XMTVI Maxamum (SHS) Powder Add-Ins (SHS) Powder Easiphen (SHS) Liquid Lophlex (SHS) Powder Milupa PKU 2-prima (Milupa) Powder Milupa PKU 2-secunda (Milupa) Powder Milupa PKU 3-advanta (Milupa) Powder Phlexy-10 Exchange System (SHS) Capsule/tablet/drink Phlexy-Vits (SHS) Powder/tablet Methylmalonic acidaemia and propionic acidaemia Phenylketonuria (PKU) PKU PKU Anamix First Spoon (SHS) Powder PKU Anamix Infant (SHS) Powder PKU Anamix Junior (SHS) Powder PKU Anamix Junior LQ (SHS) Liquid PKU cooler 10, 15, 20 (Vitaflo) Liquid Age range Birth–3 years Notes Also related conditions where intake of branched chain amino acids must be limited 1–10 years 1–10 years >3 years >8 years 1–10 years 1–8 years >8 years Birth–3 years Infants and children 1–8 years Essential and non-essential amino acids except methionine, threonine, and valine, low isoleucine content >8 years >4 years >8 years Essential and non-essential amino acids except phenylalanine >8 years 1–8 years 9–15 years >15 years >8 years Each unit (1 sachet, 10 tablets or 20 capsules) provides 10 g of amino acids except phenylalanine >11 years 6 months–5 years Birth–3 years Vitamin and mineral component of restricted therapeutic diets in PKU and similar amino acid abnormalities Contains DHA, essential and non-essential amino acids except phenylalanine Contains prebiotic oligosaccharides, AA and DHA 1–10 years Contains AA, DHA, vitamins and minerals 1–10 years >3 years Ready to drink phenylalanine free protein substitute containing DHA and EPA, vitamins, minerals and trace elements. (Continued) Table A10.2.5 (Continued) Metabolic disease Phenylketonuria Tyrosinaemia Flavouring preparations Product name (manufacturer) Age range Notes PKU express (Vitaflo) Powder PKU gel (Vitaflo) Powder PKU Lophlex LQ 10, 20 (SHS) Liquid >3 years Contains essential and non-essential amino acids except phenylalanine, carbohydrate, vitamins, minerals and trace elements PKU Start (Vitaflo) Liquid <12 months XP Maxamaid (SHS) Powder XP Maxamum (SHS) Powder Methionine-free TYR Anamix Infant (SHS) Powder TYR Anamix Infant (SHS) Powder TYR Anamix Junior (SHS) Powder TYR Anamix Junior LQ (SHS) Liquid TYR cooler (Vitaflo) Liquid TYR express (Vitaflo) Powder TYR Gel (Vitaflo) Gel XPHEN TYR Maxamaid (SHS) Powder FlavourPac (Vitaflo) Powder Modjul Flavour System (SHS) Powder 1–8 years 1–10 years >4 years >8 years Ready to drink, phenylalanine free protein substitute containing essential and non-essential amino acids, carbohydrates, vitamins, trace elements and some minerals Ready to feed phenylalanine free infant formula containing essential and non-essential amino acids, carbohydrate, fat, vitamins, minerals, trace elements, AA and DHA Phenylalanine free drink mix containing essential and non-essential amino acids, carbohydrate, vitamins, minerals and trace elements Birth–3 years For proven tyrosinaemia type 1 Birth–3 years Proven tyrosinaemia where plasma methionine concentrations are normal Proven tyrosinaemia 1–10 years >1 year >3 years >8 years Tyrosinaemia type 1 (when NTBC is used), type 2 and type 3 Contains carbohydrates, minerals, trace elements and vitamins, essential and non-essential amino acids except tyrosine and phenylalanine 1–10 years 1–8 years Tyrosinaemia type 1 (when NTBC is used), type 2 and type 3 For use with unflavoured protein substitutes AA, arachidonic acid; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; NTBC, nitisone. Table A10.2.6 Manufacturers’ websites Abbott, Abbott Laboratories Ltd Cow & Gate, Nutricia Ltd Fresenius Kabi, Fresenius Kabi Ltd Mead Johnson, Mead Johnson Nutrition Milupa, Milupa Aptamil Nestlé, Nestlé Nutrition Nutricia Clinical, Nutricia Clinical Care SHS, SHS International Ltd SMA Nutrition, Pfizer Ltd Vitaflo, Vitaflo International Ltd www.abbott.co.uk www.cowandgate.co.uk www.fresenius-kabi.co.uk/ www.meadjohnson.com www.milupa-metabolics.com www.nestlenutrition.com www.nutricia.co.uk www.shs-nutrition.com www.smanutrition.co.uk www.vitaflo.co.uk