Red List Last updated 2014/10/07
Transcription
Red List Last updated 2014/10/07
Red List Last updated 2014/10/07 Medicine Indication Decision Rationale for inclusion in the List Circumstances in which use might be appropriate Abatacept Rheumatoid Arthritis Hospital only Refer to NICE Guidelines None foreseen Acetylcysteine Mucolytic - CF, bronchiectasis and pulmonary fibrosis Hospital only Acitretin Capsules Psoriasis Hospital only Adalimumab All indications NICE TA 130, 143, 146, 187, 199 Hospital only Alicalm Aliskiren Food supplement Hypertension, to be reviewed by NICE under hypertensive guidelines ACBS APC Feb 2009 Alitretinoin Capsules Chronic hand eczema NICE TA 177 Aug 2009 Hospital only All antiretrovirals HIV Infection Hospital only London HIV Consortium Guidelines None foreseen Alprazolam Anxiety NEPFT None foreseen Alteplase Fibrinolytic NICE TA 122 Jun 2007 Hospital only Amoxapine Antidepressant NEPFT Nonformulary for NEPFT Refer to NICE Guidelines Nonformulary for NEPFT , may cause Dr Rob Gerlis, Chair Clare Morris, Chief Officer Safety concerns, strict monitoring requiremen ts and restricted availability Refer to NICE Guidelines No robust evidence to support use in place of exisitng drugs Refer to NICE Guidelines Possibly shared care with tertiary hospital None foreseen None foreseen None foreseen None foreseen None foreseen None foreseen None foreseen tardive dyskinesia Amphetamines mixed (Adderall) ADHD NEPFT Amphotericin Anagrelide Antifungal Reduction of elevated platelet counts Hospital only Hospital only Anti-coagulant test strips (CoaguChek) Anti-coagulant test strips Apraclonidine Intra ocular pressure Hospital only None foreseen Aprepitant Chemo induced nausea Hospital only None foreseen Arachis Oil Laxative and bowel cleansing solution Hospital only Aripiprazole injection IM Agitation and disturbed behaviour in schizoprenia NEPFT prescribers only RED Formulary for NEPFT None foreseen Asenapine (Sycrest) Acute phase Bipolar NEPFT Nonformulary for NEPFT Form B applications to MMG only. Atovaquone Pneumocystis pneumonia Hospital only Beclometasone tablets (Clipper) Ulcerative colitis Betaine Beta-interferon Bevacizumab Homocystinuria MS All indications Biotene Oral Balance Artifical saliva Gel Dr Rob Gerlis, Chair Clare Morris, Chief Officer Nonformulary for NEPFT None foreseen None foreseen GP or hospital managed services to be used in preference Palliative care use Rarely, by prior agreement None foreseen Clinical case not demonstrat ed Hospital only Hospital only Hospital only None foreseen ABN 2009 Refer to NICE Guidelines None foreseen None foreseen None foreseen None foreseen None foreseen Biphosphonates IV Osteoporosis, Pagets disease, hypercalcaemia of malignancy NICE TA 160/161 Jan 2011 Hospital only Bosentan Pulmonary arterial hypertension Hospital only None foreseen Botulinum Toxin A and B All indications Specialist use only None foreseen Buprenorphine Injection Analgesic Palliative use only Buspirone Anxiolytic - short term use only NEPFT prescribers only Possibily if part of a palliative care package None foreseen Butobarbital Caffeine Hypnotic Stimulants Hospital only Hospital only None foreseen None foreseen Hypercalcaemia of malignancy, Paget's disease Capreomycin TB Capsaicin patches Neuralgia, NICE CG96 Mar (Qutenza) 2010 not recommended Hospital only None foreseen Hospital only Hospital only None foreseen Carglumic acid Hyperammonaemia Hospital only None foreseen Carnitine Carnitine deficiency Hospital only None foreseen Caspofungin Certolizumab Antifungal Rheumatic disease NICE TA 186 Feb 2010 Hospital only Hospital only None foreseen None foreseen Calcitonin injection Cetrorelix Chemotherapy and IV) Female infertility (oral Cytotoxic drugs Chloroquine injection Malaria Chlorpromazine Antipsychotic injection (Largactil and generic) Dr Rob Gerlis, Chair Clare Morris, Chief Officer Refer to NICE Guidelines NEPFT None foreseen Refer to NICE Guidelines Refer to NICE Guidelines Hospital only Hospital only None foreseen None foreseen Specialist prescribing None foreseen NEPFT Nonformulary for NEPFT Erratic unpredictab le absorption. Cardiac risk. Choriogonadotropin alfa Female infertility Hospital only Chorionic gonadotropin Female infertility Hospital only Cilostazol Intermittent claudication NICE TA 223 May 2011 does not advocate use Cinacalcet Hyperparathyroidism NICE TA 117 Jan 2007 Clomethiazole None foreseen Refer to NICE Guidelines None foreseen Hospital only Refer to NICE Guidelines None foreseen Addiction/ withdrawal. NICE CG 115 Feb 2011 NEPFT prescribers only Refer to NICE Guidelines None foreseen Clonazepam injection Rapid tranquillisation Anxiety Clozapine Treatment resistant schizophrenia. AMBER for people with LD. NICE CG 82 Mar 2009 RED Formulary for NEPFT Nonformulary for NEPFT RED Formulary for NEPFT Refer to NICE guidelines. None foreseen Clorazepate NEPFT prescribers only NEPFT Co-careldopa intestinal gel (Duodopa) Drugs used in parkinsonism and related disorder None foreseen Colesevelam Lipid regulating drugs None foreseen Co-proxamol Analgesic Dr Rob Gerlis, Chair Clare Morris, Chief Officer NEPFT prescribers only Highly toxic in even small overdoses. The MHRA has withdrawn the marketing authorisatio n for coproxamol due to the poor risk/benefit profile of the drug None foreseen None foreseen None foreseen. For patients currently receiving the drug and unable to switch to an alternative, continued provision of the unlicensed product may be made on the prescribers responsibility Cosmofer parenteral Anaemia Hospital only None foreseen Cyclizine inj Chemo induced nausea Palliative care use Possibily if part of a palliative care package Cytotoxic drugs parenteral and oral Cytotoxic drugs Hospital only None foreseen Daclatasvir (Daklinza film coated tablets) Liver disorders – licensed for use as part of combination therapy for treating chronic HCV infection in adults. Pneumocystis pneumonia, dermatitis herpetiformis Hospital only Specialist prescribing None foreseen Daptomycin Antibiotic Specialist prescribing None foreseen Darbepoetin Alfa Anaemia of chronic renal failure NICE TA 142 May 2008 Hospital only Refer to NICE Guidelines None foreseeen Darifenacin Urinary frequency, urgency and incontinence. NICE CG 40 Oct 2006 Little benefit over oxybutynin Refer to NICE Guidelines None foreseen Deferasirox Deferiprone Degarelix Anaemia Anaemia Advanced Prostate cancer Hospital only Hospital only Hospital only Dapsone Dr Rob Gerlis, Chair Clare Morris, Chief Officer APC April 2010, Not approved on basis of:Inconclusive evidence of outcome benefit; No independen t comparative studies: No direction from NICE; Lack of outcome data None foreseen None foreseen None foreseen Degludec insulin Type 1 & Type 2 diabetes mellitus Depigmentation treatments Hospital only Individual care protocol required under the specialist Hospital only None foreseen None foreseen None foreseen Desferrioxamine Desmopressin 15mcg/ml inj Anaemia All indications Hospital only Hospital only Dexamethasone Intravitreal implant for the treatment of macular oedema, secondary to retinal vein occlusion Hosptal only DHEA (Dehydroepiandroste rone) APC July 2014, not approved on basis of:is noninferior to other longacting insulin analogues; need for holistic review of patient. NICE TA229 July 2011 Hospital only None foreseen Dialamine Diamorphine intranasal and topical (unlicensed) Food supplement Analgesic ACBS Hospital only None foreseen None foreseen Diazepam Injection Hypnotic Hospital only None foreseen Diazoxide Emergency hypertension Hospital only None foreseen Dibotermin Bone morphogenic protein Hospital only None foreseen Diloxanide Diphenylcyopropeno ne Amoebiasis Alopecia Hospital only Hospital only None foreseen None foreseen Disodium edetate eye Chelating agent drops Hospital only None foreseen Dolasetron Chemo induced nausea Hospital only None foreseen Dornase Alpha CF Hospital only None foreseen Dr Rob Gerlis, Chair Clare Morris, Chief Officer Dosulepin, Dothiepin (formerly Prothiaden) NEPFT Drugs affecting Drugs affecting gonadrophins gonadrophins (Cetrorelix, ganirelix, buserelin, nafarelin, goserelin Hospital only Duloxetine Stress urinary incontinence See document list Eculizumab Eflornithine cream Anaemia Female facial hair Hospital only Elemental 028 extra Enteral Feeds Hospital only Eltrombopag ITP NICE TA 205 Oct 2010 Hospital only Enzyme replacement CF therapy Dr Rob Gerlis, Chair Clare Morris, Chief Officer Hospital only Nonformlary for NEPFT Toxic in overdose. Cardiotoxic. Except existing patients with no CI. Alternatives include lofepramine , amitriprtylin e, trazodone mirtazepine. Not recommend ed in NICE CG 90 2010 Existing patients with no contra indications continuing care guidance to be used None foreseen Only modest enefit seen in women with severe SUI, and no benefit in mild SUI NICE CG 40 Oct 2006 No substantial evidence of benefit ACBS Refer to NICE Guidelines None foreseen None foreseen None foreseen None foreseen None foreseen None foreseen Erdosteine Acute exacerbations of chronic bronchitis Initiated by specialist Support from secondary care Ergocalciferol 300, 000 IU inj Vitamin D deficiency Hospital only None foreseen Ergometrine Drugs used in obstetrics Hospital only None foreseen Erythropoietin Anaemia NICE TA 142 May 2008 Hospital only Escitalopram (Cipralex) Antidepressant NEPFT prescribers only Etanercept Rheumatic disease Hospital only Etanercept Psoriasis NICE TA 103 Jul 2006 Hospital only Ethambutal TB Specialist prescribing Ethosuximide Epilepsy NEPFT Fansidar Malaria Specialist prescribing Fesoterodine Urinary frequency, enuresis and incontinence Filgrastim Fingolimod Anaemia MS, NICE TA 254 April 2012 Dr Rob Gerlis, Chair Clare Morris, Chief Officer Refer to NICE Guidelines RED formulary for NEPFT. Please prescribe citalopram instead unless there are strong clinical reasons. NICE TA 35, 130, 143, 199 Refer to NICE Guidelines Named patient, consultant inititation only using Form B. None foreseen None foreseen None foreseen Discontinue d by manufactur ers. Existing patients to be reviewed by specialist care None foreseen, refer exisitng patients back to specialist care None foreseen Non formulary West & Mid Essex Hospital only Hospital only None foreseen Refer to NICE Guidelines None foreseen None foreseen None foreseen Flavoxate Female urinary incontinence & OAB. NICE CG 40 Oct 2006 NHS West Essex Female Urinary Incontinence Formulary April 2010 Hospital only Refer to NICE Guidelines None foreseen Flecainide Injection Anti arrhythmic NICE CG 36 Jun 2006 REfer to NICE Guidelines None foreseen Fludroxycortide Tape Haelan® Recalcitrant dermatoses Hospital only NHS West Essex Dermatolog y Formulary None foreseen Flunitrazepam Hypnotic NEPFT None foreseen Fluocinolone Intravitreal implant (Iiuvien) Vision impairment associated with chronic diabetes macular oedema Hospital only Nonformlary for NEPFT . Hypnotic of misuse. Refer to NICE Guidelines Fluorouracil cream Photodamage and basal cell carcinoma Hospital only Fluphenazine (Moditen 1mg) oral Anti-psychotic None foreseen None foreseen NEPFT Nonformulary for NEPFT Discontinued, review exisitng patients Flurazepam (formerly Insomnia Dalmane) NEPFT Nonformulary for NEPFT None foreseen Fluvoxamine Antidepressant. NICE CG 90 2010 Hospital only Refer to NICE Guidelines None foreseen Folic acid Injection Anaemia Hospital only None foreseen Follitropin alfa and Female infertility beta Hospital only None foreseen Fondaparinux Fosphenytoin Anti-coagulant Epilepsy NICE CG 137 Jan 2012 Hospital only Hospital only None foreseen None foreseen Fulvestrant Advanced breast cancer. NICE TA 239 Dec 2011, not recommended Hospital only Fumaric acid esters Psoriasis Hospital only Dr Rob Gerlis, Chair Clare Morris, Chief Officer Refer to NICE Guidelines Refer to NICE Guidelines None foreseen None foreseen Galantamine TABLETS Alzheimer's disease NEPFT Galsulfase Mucopolysaccharidosis VI Hospital only None foreseen Gelclair mouthwash Stomatitis Hospital only None foreseen Generaid standard or Plus Specialised formualtions Hospital only ACBS None foreseen Gingko Biloba Alzheimers disease NEPFT Risk of cerebral haemorrhage. Glatiramer Glycopyrronium Bromide Powder MS Hyperhidrosis Hospital only Hospital only Nonformulary NEPFT. Not available on NHS. ABN 2009 Glycopyrronium Bromide Tablets Hyperhidrosis Hospital only None foreseen Golimumab RA, AS, PsA Hospital only NHS West Essex Dermatolog y Formulary NICE TA 220 April 2011, TA 225 Jun 2011, TA 233 Aug 2011. Granisetron Chemo induced nausea Hospital only Grazax Grass pollen allergy Gut decontamination regimen Dr Rob Gerlis, Chair Clare Morris, Chief Officer Nonformulary NEPFT. USE SR CAPSULES (ONCE DAILY) or LIQUID to avoid prescribing errors. None foreseen None foreseen None foreseen None foreseen JPG Nov 2010- not prescribed in primary or secondary care Hospital only None foreseen None foreseen None foreseen Haloperidol injection Antipsychotic NEPFT prescribers only Hepatitis therapy Hepatitis Hospital only HIV treatments Human arginate HIV Infection Metabolic disorders Hospital only Hospital only None foreseen None foreseen Human chorionic gonadotropins Female infertility Hospital only None foreseen Human menapausal gonadotropins Female infertility Hospital only None foreseen Human papilloma virus vaccine Prevention of cervical cancer Hyaluronic Acid Hyaluronidase Osteoarthritis Extravasation Hospital only Hospital only None foreseen None foreseen Hydromorphone Hydroxycarbamide Analgesic CML Hospital only Initiated by specialist None foreseen Support from secondary care Hydroxycarbamide Chemotherapy Sickle cell disease Hospital only Possibly shared care arrangement with teritary centres Dr Rob Gerlis, Chair Clare Morris, Chief Officer RED formulary for NEPFT. Should have ECG before use. Alternatives for community include risperidone quicklets, olanzapine velotabs NICE TA 173 July 2009, TA 153, Aug 2008, TA 154 Aug 2008, TA 96 Feb 2006, TA 106 Aug 2006, To be prescribed as part of the nationally agreed vaccination programme only None foreseen None foreseen None foreseen Hyoscine Hydrobromide Injection Palliative care Hospital only Possibly if part of a palliative care package Hypertonic Saline Mucolytic for CF/ bronchiectasis Hospital only Possibly shared care arrangement with teritary centres Hospital only None foreseen Ibandronic injection acid All indications Idursulfase Mucopolysaccharidosis VI Hospital only None foreseen Imiglucerase Mucopolysaccharidosis VI Hospital only None foreseen Imiquimod External/perianal wats Hospital only NHS West Essex Dermatolog y Formulary None foreseen Immunoglobulins Immunoglobulin Hospital only DoH Clinical Guidelines for the use of Ig Aug 2011 None foreseen In vitro fertilization – all medicines Hospital only None foreseen Infliximab Inositol nicotinate All indications Peripheral vascular disease. NICE TA 223 May 2011 does not advocate use Hospital only NICE Refer to NICE Guidelines None foreseen None foreseen Insulin pumps Diabetes NICE TA 151 July 2008 Hospital only Refer to NICE Guidelines None foreseen Interferon Alfa-2B Interferon Beta Interferon gamma Iodine Aqueous Solution All indications All indications All indications Thyrotoxicosis pre-op Hospital only Hospital only Hospital only Hospital only Isocarboxazid Antidepressant MAOI NEPFT Isotretinoin Capsules Acne Hospital only Dr Rob Gerlis, Chair Clare Morris, Chief Officer None foreseen None foreseen None foreseen None foreseen Nonformualry for NEPFT NHS West Essex Dermatolog y Formulary None foreseen None foreseen Ivermectin Parasitic Infections IVF drugs for private patients Infertility KetoCal Specialised formualtions Hospital only Ketorolac Kindergen Eye drops Specialised formualtions Hospital only Hospital only Lariam Laronidase Malaria Mucopolysaccharidosis VI Hospital only Hospital only Lenalidomide Multiple myeloma NICE TA 171 Jun 2009 Hospital only Lenograstim Levofloxacin (oral) Neutropenia Antibiotic Hospital only Hospital only Levomepromazine injection and oral Antipsychotic, anxiety in terminal care May be prescribed caution with use Lidocaine (Versatis) Patches Diabetic neuropathy. NICE CG 96 Mar 2010 Linezolid Antibiotic Liothyronine Injection Hypothyroid Dr Rob Gerlis, Chair Clare Morris, Chief Officer Hospital only WE Pain Formlary 2010. For use by GP only whilst awaiting referral Hospital only Hospital only NHS West Essex Dermatolog y Formulary If the patient does not meet the criteria for NHS IVF treatment thent he whole treatment is private and the drugs can not be prescribed on the NHS ACBS ACBS None foreseen None foreseen. Where NHS funds IVF, all drugs to be provided by specialists None foreseen None foreseen None foreseen None foreseen None foreseen Refer to NICE Guidelines None foreseen None foreseen None foreseen NEPFT Caution do not use in ambulant patients over 50 yrs Refer to NICE Guidelines Possibly part of a palliative care package Only for use in localised pain in patients unable to take oral medication due to a medical condition/ disability None foreseen None foreseen Lofexidine Opioid dependence NICE CG 52 2008 NEPFT prescribers only Loprazolam Insomnia NEPFT Lorazepam Injection All indications Hospital only Lormetazepam Insomnia NEPFT RED formulary for NEPFT. Refer to NICE Guidelines Nonformulary NEPFT. None foreseen None foreseen None foreseen Nonformulary NEPFT. Low molecular Treatment of VTE in cancer Initiated by weight heparins patient. specialist None foreseen CHECK PAH Low molecular Prophylaxis, NICE CG 92 weight heparins Jun 2011 Hospital only Lutropin alfa Malaria prophylaxis Female infertility Travel Hospital only Malarone Maprotiline Malaria Antidepressant Hospital only NEPFT Mecasermin Medium-Chain Triglyceride (MCT) oil Somatomedins Specialised formualtions Hospital only Hospital only Mefloquine Melatonin SR (Circadin) for adults Malaria short course for people over 55 with primary insomnia. Hospital only NEPFT Melperone Meprobamate Anti-psychotic Anxiety Hospital only NEPFT Mercaptamine Mucopolysaccharidosis VI Hospital only None foreseen Mercaptopurine Metabolic Mineral Mixture All indications Food supplements Hospital only Hospital only None foreseen None foreseen Dr Rob Gerlis, Chair Clare Morris, Chief Officer Refer to NICE Guidelines Not reimbursabl e under the NHS Nonformulary NEPFT. ACBS Nonformulary NEPFT. Nonformulary for NEPFT ACBS Support from secondary care None foreseen Provide a private prescription None foreseen May cause convulsions. None foreseen None foreseen None foreseen Form B applications to MMG only. CHILDREN - See yellow list, continuing care guidance. None foreseen None foreseen Methacholine Inhalation Respiratory (other) Hospital only None foreseen Methadone injection Opioid dependence ( Physeptone) NEPFT Nonformulary for NEPFT Refer to local CDAT. Methadone tablet Opioid dependence ( Physeptone) NEPFT Nonformulary for NEPFT Refer to local CDAT. Methotrexate Cancer Methoxsalen Psoriasis Methoxypolyethylene Anaemia glycol epoetin beta Hospital only Hospital only Hospital only Methyl Aminolevulinate Cream or gel Photodynamic therapy Hospital only 5-Methoxypsoralen Psoriasis Hospital only 8-Methoxypsoralen Psoriasis Hospital only Mianserin Bolvidon) (formerly Antidepressant Midazolam oral liq. (As Epistat 10mg/ml) Epilepsy (alternative to rectal diazepam) Dr Rob Gerlis, Chair Clare Morris, Chief Officer NEPFT NEPFT None foreseen None foreseen None foreseen NHS West Essex Dermatolog y Formulary NHS West Essex Dermatolog y Formulary NHS West Essex Dermatolog y Formulary Nonformulary for NEPFT None foreseen Nonformulary for NEPFT. Prescribe Buccolam 5mg/ml in preference by brand name only. Buccolam is licensed for children. Epistat is unlicensed, CARE with strengths. Individual care protocol required. None foreseen None foreseen S/E blood dyscrasias Midodrine Hypotension associated with haemodialysis or heptorenal syndrome Hospital only Miglustat Metabolic disorders Hospital only None foreseen Minoxidil Hypertension Hospital only None foreseen Misoprostol Modafinil Obstetric use narcolepsy only Hospital only Neurologist initiation, not usually mental health. None foreseen Moxifloxacin Nalmefene Antibiotic for alchohol use reduction. Hospital only NEPFT Natalizumab MS NICE TA 127 Aug 2007 Hospital only Neostigmine Neuromuscular disorders Hospital only None foreseen Hospital only None foreseen New fill for facial lipodystrophy Unlicensed None foreseen Nonformulary for NEPFT Nonformulary for NEPFT Refer to NICE Guidelines None foreseen None foreseen None foreseen Nicotinamide Nimodipine Vitamin Celebral vascular spasm Hospital only Hospital only None foreseen None foreseen Nitisinone Nitrazepam Tyrosinaemia Insomia Hospital only long half life, muscle relaxant, increases reaction time, leads to falls in elderly/debilita ted. None foreseen Review existing patients. Refer to Trust 'Guidance for Medicines for sleeplessness' for planned withdrawal/cha nge to shorteracting drug. Novorapid Vial Ofloxacin 0.3% Insulins Anti-infective eye preperation Hospital only Hospital only Olanzapine embonate long acting injection Antipsychotic Requires at least 3 hours observation after each administration Dr Rob Gerlis, Chair Clare Morris, Chief Officer Nonformulary for NEPFT None foreseen None foreseen Nonformulary for NEPFT Do not apply on form B unless training is done. Olanzapine IM injection (Zyprexa) Antipsychotic NEPFT prescribers only RED formulary for NEPFT None foreseen Omalizumab Asthma NICE TA 133 Nov 2007, TA 201 Oct 2010 Hospital only Refer to NICE Guidelines None foreseen Omega-3-acid (Omacor) Schizoprenia, bipolar disorders, psychosis, Alzheimer's NEPFT prescribers only. None foreseen Omega-3-acid (Omacor) Hypertriglyceridaemia Omega-3-marine (Maxepa) Schizoprenia, bipolar disorders, psychosis, Alzheimer's NEPFT prescribers only RED formulary for NEPFT. Advise patient to purchase if possible. Review concordanc e. Reviewed by APC and not recommend ed RED formulary for NEPFT. Advise to purchase and check concordanc e. Ondansetron Injection Chemo induced nausea Hospital only Possibly part of a palliative care package Ondansetron oral Chemo induced nausea Hospital only None foreseen Oseltamivir for influenza treatment outside of NICE guidelines Hospital only None foreseen Osteogenic factor-1 (OP1) Hospital only None foreseen None foreseen Possibly part of a palliative care package bone Oxandrolone Oxycodone Injection Anabolic steroids Analgesic Hospital only Hospital only Paediatric Seravit Palonosetron Food supplements Chemo induced nausea Hospital only Hospital only Dr Rob Gerlis, Chair Clare Morris, Chief Officer ACBS If initiated by cardiologist None foreseen None foreseen None foreseen Paraldehyde injn Epilepsy Hospital only Parecoxib Peri operative analgesic Hospital only Paricalcitol Hyperparathyroidism Hospital only Pegaptanib Ocular disorders Hospital only Pegfilgrastim Pegvisomant Pegylaytd interferon Neutropenia Acromegaly All indications Hospital only Hospital only Hospital only None foreseen None foreseen None foreseen Penicillamine Metabolic Disorders Hospital only None foreseen Pentamidine Pneumocystis pneumonia Hospital only None foreseen Pentoxifylline Peripheral vascular disease NICE TA223 may 2011 does not advocate use Peptamen HN Perative Phenoxybenzamine Enteral Feeds Enteral Feeds Phaeochromocytoma Hospital only Hospital only Hospital only Pigmanorm Melanin induced hyperpigmentation Hospital only Pilocarpine tablets Xerostomia Hospital only Pimozide Antipsychotic NEPFT prescribers only Pirenzepine Antipsychotic Posaconazole Antifungal NEPFT prescribers only. Not licensed. For side effects of Clozapine Hospital only Dr Rob Gerlis, Chair Clare Morris, Chief Officer Nonformulary for NEPFT. Glass or plastipak syringes only. Form B application. None foreseen NICE TA 155 Aug 2008 None foreseen Refer to NICE Guidelines None foreseen ACBS ACBS None foreseen None foreseen None foreseen RED formulary for NEPFT. Marked side effects. Annual ECG recommend ed. RED formulary for NEPFT None foreseen None foreseen None foreseen Povidone iodine eye drops Antibacterial Primaquine Malaria Primidone (formerly Epilepsy Mysoline) Probenacid patient) (named Gout and cytotoxic induced hyperuricaemia Hospital only None foreseen Hospital only Prodrug for phenobarbiton e. Except existing patients. Difficulties with supply. Hospital only None foreseen None foreseen Prochlorperazine Antipsychotic NEPFT Proguanil Malaria Antipsychotic Hospital only Difficult to obtain. Unlicensed in UK. erratic unpredictable absorption, not recommended by BNF. Alternatives include promethazine, levomepromazi ne, pericyazine, chlorpromazine , fluphenazine Promazine IM Promazine oral (formerly Sparine) Antipsychotic Propantheline Female urinary incontinence & OAB. NICE CG 40 OCT 2006 does not recommend Propiverine Female urinary incontinence. NICE CG 40 OCT 2006 does not recommend ProSource Pulmonary hypertension treatments Food supplements Pulmonary arterial hypertension Dr Rob Gerlis, Chair Clare Morris, Chief Officer NHS West Essex Female Urinary Incontinence Formulary April 2010 NHS West Essex Female Urinary Incontinence Formulary April 2010 Hospital only Hospital only Nonformulary for NEPFT None foreseen Not recommend ed for psychosis Nonformulary for NEPFT None foreseen None foreseen None foreseen Nonformulary for NEPFT None foreseen Refer to NICE Guidelines None foreseen Refer to NICE Guidelines None foreseen ACBS None foreseen PUVASoralen-8 1.2% Bath Additive Psoriasis Hospital only Pyrazinamide Pyrimethamine Quinagolide TB Malaria Hyperprolactinaemia Hospital only Hospital only Hospital only None foreseen None foreseen Quinine Injection and Oral Malaria Hospital only None foreseen Ranibizumab Ocular disorders Hospital only NICE TA 155 Aug 2008 None foreseen Ranolazine Angina. NICE CG 126 Jul 2011 Refer to NICE Guidelines None foreseen Ribavirin Risperidone oral All indications Antipsychotic children and adolescents Check Cardiac network position. Hospital only Hospital only Rituximab Cancer, haematology, rheumatology Hospital only Roflumilast COPD NICE TA 244 Jan 2012 use in clinical trials only Hospital only Refer to NICE Guidelines None foreseen Romiplostim ITP NICE TA 221 April 2011 Hospital only None foreseen Ropinirole Restless legs syndrom Rotigotine Parkinsons Hospital only Refer to NICE Guidelines APC reviewed and not recommend ed JPG Nov 2010 - short term use in secondary care only Saccromyces boulardi Prevention of clostridium difficile Hospital only None foreseen Salicylic Acid 40% in WSP Ointment All indications Hospital only None foreseen Sativex spray Secobarbital cannabis MS Hypnotic Dr Rob Gerlis, Chair Clare Morris, Chief Officer Hospital only Hospital only NHS West Essex Dermatolog y Formulary Adults NEPFT None foreseen None foreseen Adults None foreseen JPG Sept 2010 - not recommend ed None foreseen None foreseen None foreseen None foreseen Sertindole Antipsychotic Sildenafil Pulmonary arterial hypertension Silver Nitrate 75% or 95% applicator Warts Hospital only Sodium Acid Phosphate 1mmol/ 1ml oral liquid Phosphate supplement Hospital only None foreseen Sodium Bicarbonate Chronic acidosis 8.4% oral solution Hospital only None foreseen Sodium Irrigation Hospital only None foreseen Sodium Citrate Constipation Sodium hyaluronate Interstitial cystitis & chondroitin iAluRil® Hospital only Hospital only None foreseen Sodium oxybate Nacolepsy with cataplexy Hospital only None foreseen Sodium Phenylbutyrate Metabolic disorders Hospital only None foreseen Sodium Phenylbutyrate Metabolic disorders Hospital only None foreseen Sodium Picosulfate Bowel cleansing Hospital only None foreseen Somatokine Growth hormone insensitivity in children Hospital only None foreseen Spectinomycin Streptomycin Survimed OPD St. Johns Wort (Natures Aid 333mg or 500mg, Power 200mg, 500mg, Complex caps 334mg by Vega, or FSC 500mg) Antibiotic TB Enteral Feeds Antidepressant. Hospital only Hospital only Hospital only CARE with bioavailability and interactions. None foreseen None foreseen None foreseen None foreseen Tadalafil Pulmonary arterial hypertension Hospital only Chloride Bladder clot retention Dr Rob Gerlis, Chair Clare Morris, Chief Officer NEPFT prescribers only Hospital only RED formulary for NEPFT None foreseen None foreseen Non formulary for NEPFT. Patients may be advised to purchase. See NICE guidelines for mild depression. None foreseen Tamoxifen oral Hospital only None foreseen Initiated by Specialist None foreseen Sclerosing peritonitis in patients with end stage renal failure Tapentadol SR Unresolved pain and oncology pain Targinact Teriparitide Analgesic Osteoporosis, Pagets disease, hypercalcaemia of malignancy NICE TA 160/161 Jan 2011 Hospital only Refer to NICE Guidelines Testosterone patch Low libido in women with surgically induced menopausal who are receiving oestrogen Tetrabenazine Drugs used in parkinsonism and related disorder Hospital only None foreseen Tetracosactide Injection/ Depo Hypothalamic and pituritary hormones and anti-oestrogens Hospital only None foreseen Tetrahydobiotin Metabolic disorders Hospital only None foreseen Thalidomide Ticagrelor All indications ACS + aspirin. NICE TA 236 Oct 2011 Hospital only Initiated by specialist None foreseen Check cardiac network Tocilizumab RA & JIA, NICE TA 238 Dec 2011 & TA 247 Feb 2012 Hospital only Tolterodine Female urinary incontinence. NICE CG 40 OCT 2006 NHS West Essex Female Urinary Incontinence Formulary April 2010 Hospital only Hospital only REfer to NICE Guidelines NEPFT Nonformulary Tolvaptan Low sodium Total Parenteral IV feed Nutrition Tranylcypromine Antidepressant MAOI Dr Rob Gerlis, Chair Clare Morris, Chief Officer Risk-benefit ratio not assessed, APC < 2009 None foreseen check formulary None foreseen Refer to NICE Guidelines Refer to NICE Guidelines None foreseen check formulary None foreseen None foreseen None foreseen None foreseen None foreseen for NEPFT Travel vaccines Travel Tretinoin Triclofos Leukaemia Paediatric insomnia Hospital only NEPFT Trifluoperazine Anxiety. Antipsychotic. All preparations are discontinued NEPFT Triumeq (dolutegravir, abacavir, lamivudine) 50mg, 300mg, 600mg tablets Tropisetron Treatment of HIV infected adults and adolescents above 12 years of age weighing at least 40kg. Hospital Only. Chemo induced nausea Hospital only Trospium Female urinary incontinence NICE CG 40 2006 Tryptophan Antidepressant Unfractionated Heparin Anti-coagulant NHS West Essex Female Urinary Incontinence Formulary April 2010 NEPFT prescribers only Hospital only Urofollitrophin Ustekinumab Female infertility Psoriasis. NICE TA 180 Sept 2009 Hospital only Hospital only Vardenafil Erectile dysfunction NEPFT Vibro-Pulse Cellulitis, Venous leg ulcers disposable covers Vibro-Pulse devise non-prescribable on fp10 Dr Rob Gerlis, Chair Clare Morris, Chief Officer Not to be prescribed on the NHS except for designated exceptions see Green Book Nonformulary for NEPFT Nonformulary for NEPFT None foreseen None foreseen None foreseen None foreseen None foreseen Refer to NICE Guidelines None foreseen RED formulary for NEPFT None foreseen None foreseen Refer to NICE Guidelines Nonformulary for NEPFT. Cochrane review finds insufficient evidence on CV therapy None foreseen None foreseen Restricted in NHS. See BNF. None foreseen Vigabactrin Epilepsy NEPFT Vitamin B Intravenous Injection Vitamin B Hospital only Voriconazole Zaleplon (Sonata) Antifungal Insomnia. NICE TA 77 April 2004 Hospital only NEPFT Ziconotide Zoledronic Acid Zotepine (Zoleptil) Analgesic All indications Antipsychotic (for Schizophrenia) Hospital only Hospital only NEPFT Zuclopenthixol acetate injection Antipsychotic NEPFT prescribers only Dr Rob Gerlis, Chair Clare Morris, Chief Officer Nonformulary for NEPFT Except for existing patients None foreseen None foreseen Refer to NICE Guidelines APC <2009 Nonformulary for NEPFT , high side effect profile. Discontinue d. RED formulary for NEPFT None foreseen None foreseen None foreseen None foreseen None foreseen None foreseen