STUDY PROGRAM 2015/2016 Elective and Optional subjects
Transcription
STUDY PROGRAM 2015/2016 Elective and Optional subjects
University of Pécs Medical School GENERAL MEDICINE Major STUDY PROGRAM 2015/2016 Elective and Optional subjects UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 1st Semester OAE-BFA ______ Physical Basis of Biophysics ____________________________________________________________ 7 OAE-BO1 ______ Biophysics Seminars 1 _________________________________________________________________ 9 OAE-H1A ______ Medical Hungarian 1A - Communication Skills ____________________________________________ 10 OAE-H1B ______ Medical Hungarian 1B - Language Points _________________________________________________ 12 OAE-MS1 ______ Experiments in Molecular Cell Biology 1 _________________________________________________ 14 OAE-N06 _______ Medical Terminology _________________________________________________________________ 16 OAE-ORE ______ Medical Rehabilitation in Daily Practice __________________________________________________ 18 OAE-OTT ______ History of Medicine __________________________________________________________________ 20 OAF-BAL ______ Mineral and Spa Waters, Balneology_____________________________________________________ 22 OAF-BBM ______ Introduction to Biometrics _____________________________________________________________ 24 OAF-BFM ______ Problem Solving in Biometrics _________________________________________________________ 26 OAF-DME ______ Cancer is Preventable! ________________________________________________________________ 28 OAF-FJE _______ Health Promotion ____________________________________________________________________ 30 OAF-GOM ______ Poisonous Mushrooms ________________________________________________________________ 32 OAF-KEF ______ Physical Basis and Application of Medical Imaging Techniques _______________________________ 34 OAF-KKN ______ The Environment and the Environmental Monitoring Public Health Relevance____________________ 36 OAF-MPR ______ Marketing in Different Levels of Prevention _______________________________________________ 38 OAF-MUV ______ Psychiatry and Art ___________________________________________________________________ 40 OAF-NET ______ Internet (Computer Applications 2) ______________________________________________________ 42 OAF-SL1 _______ Stanford Lectures I: Behavioural Genetics ________________________________________________ 43 OAF-TMR ______ University Learning Skills _____________________________________________________________ 46 OAF-VB1 ______ How to Take the Exam in Molecular Cell Biology? 1 ________________________________________ 48 2nd Semester OAE-ABI _______ Applied Biometrics __________________________________________________________________ 49 OAE-ANA ______ Medical English 2/a - Presentation Techniques _____________________________________________ 51 OAE-ANB ______ Medical English 2/b - Taking Medical Case Histories in English _______________________________ 53 OAE-BO2 ______ Biophysics Seminars 2 ________________________________________________________________ 55 OAE-BVK ______ Chemistry of Bioactive Organic Compounds ______________________________________________ 56 OAE-ELH ______ Obesity - The „Epidemic” of the Modern Age _____________________________________________ 58 OAE-EMA ______ Basic Principles of Electron Microscopy in Clinical Practice and Biological Research ______________ 59 OAE-H2A ______ Medical Hungarian 2A - Communication Skills ____________________________________________ 61 OAE-H2B ______ Medical Hungarian 2B - Language Points _________________________________________________ 63 OAE-MOM _____ Molecular Medicine __________________________________________________________________ 65 OAE-MS2 ______ Experiments in Molecular Cell Biology 2 _________________________________________________ 67 OAE-TAR ______ Nutrition and Cancer _________________________________________________________________ 69 OAE-TBG ______ Dissection Practices in Regional Anatomy ________________________________________________ 71 OAF-ATS ______ Health Effects of Alternative Dietary Habits _______________________________________________ 73 OAF-BET ______ Health Science of Wine _______________________________________________________________ 75 OAF-CIR _______ The Cytoskeletal System ______________________________________________________________ 77 OAF-EGN ______ Epigenetics - Non-genetic Inheritance and its Medical Aspects ________________________________ 79 OAF-EPR _______ Use of the EPR Spectroscopy on Biological Structures_______________________________________ 81 OAF-EUA ______ Basic Principles of Health Care Provision in the European Union ______________________________ 83 OAF-FTA ______ Basics of Phytotherapy ________________________________________________________________ 85 OAF-GSE ______ Basics of Medical Equipment __________________________________________________________ 87 OAF-HEV ______ Medical Aspects of Human Evolution ____________________________________________________ 89 OAF-HSN ______ Humanitarian Assistance and its Medical and Health Care Aspects _____________________________ 91 OAF-IZM _______ Molecular Basis of Muscle Function _____________________________________________________ 94 OAF-JEA _______ Diseases of Signal Transduction ________________________________________________________ 96 OAF-KEZ ______ Biological Basics of Handwriting Analysis. Applications in the Medical Practice __________________ 98 OAF-KFO ______ Capillary Electrophoresis in Laboratory Diagnostics _______________________________________ 100 OAF-KTE ______ Different Nations’, Religions’ Dietary Habits in Nutritional and Health Science Aspects ___________ 102 OAF-N04 _______ Anatomical Terminology _____________________________________________________________ 104 OAF-N07 _______ Clinical Terminology ________________________________________________________________ 106 OAF-NOA ______ Neuroanthropology _________________________________________________________________ 108 OAF-PLH ______ The Placebo Effect __________________________________________________________________ 110 OAF-POG ______ Population Genetics and the Practical Usage of its Results ___________________________________ 112 2 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-ROE ______ Health Status and Health Care of Ethnic Minorities in the EU (Challenges, Tasks and Possibilities) __ 114 OAF-SL2 _______ Stanford Lectures II: Behavioural Genetics _______________________________________________ 116 OAF-SMP ______ Pathology of the Cell Nucleus _________________________________________________________ 118 OAF-VB2 ______ How to Take the Exam in Molecular Cell Biology? 2 _______________________________________ 120 OAF-VVE ______ Vaccination, Anti-Vaccination Movements: Do More Harm than Good ________________________ 121 3rd Semester OAE-APK ______ Preparation of Anatomical Demonstration Material ________________________________________ 123 OAE-BKF ______ Biochemistry - Questions and Answers __________________________________________________ 124 OAE-EFI _______ Electrophysiology __________________________________________________________________ 126 OAE-EHS ______ Hunger, Satiety and Disturbances of Body Weight Regulation ________________________________ 128 OAE-EPS _______ Health Psychology __________________________________________________________________ 130 OAE-H3A ______ Medical Hungarian 3A - Basics of Medical Communication _________________________________ 132 OAE-H3B ______ Medical Hungarian 3B - Medical Communication in Practice ________________________________ 134 OAE-HOS ______ Hormonal Regulatory Mechanisms in Health and Disease ___________________________________ 136 OAF-AEM ______ Sell yourself! - Presentation Techniques in Healthcare ______________________________________ 138 OAF-ANH ______ Borderline Anatomy _________________________________________________________________ 141 OAF-ASE ______ Presentation of Case Reports in English _________________________________________________ 142 OAF-BUS ______ Biotechnology from a Business Perspective ______________________________________________ 144 OAF-EBK ______ Food Safety and Crisis Situations ______________________________________________________ 146 OAF-EFA ______ Ethnopharmacobotany _______________________________________________________________ 148 OAF-ETA ______ Human Nutrition and Dietetics ________________________________________________________ 150 OAF-FEA ______ Basics of Infectious Disease Epidemiology _______________________________________________ 152 OAF-FIT _______ Phytotherapy ______________________________________________________________________ 154 OAF-GMS ______ Genetically Modified Organisms and Our Health __________________________________________ 156 OAF-GP1 _______ Writing and Managing Successful Grant Proposals 1 _______________________________________ 158 OAF-HAK ______ The Chemistry of Death ______________________________________________________________ 160 OAF-JNF _______ History of Epidemics and the Great Discoveries ___________________________________________ 162 OAF-KAM ______ Clinical Anatomy ___________________________________________________________________ 164 OAF-MC1 ______ Methods in Molecular Cell Biology I ___________________________________________________ 165 OAF-MGE ______ Molecular Gerontology ______________________________________________________________ 167 OAF-MNE ______ Molecular Neuroendocrinology ________________________________________________________ 169 OAF-MTS ______ Altered States of Consciousness in the Somatic Medicine ___________________________________ 171 OAF-N37 _______ Anatomical Terminology 2 ___________________________________________________________ 173 OAF-STH ______ Advanced Histology _________________________________________________________________ 175 OAF-TD1 _______ Student Project Research 1____________________________________________________________ 177 OAF-TEK ______ Technological Disasters and Their Impact on Health _______________________________________ 178 OAF-TMB ______ Molecular Biology of Tumors _________________________________________________________ 180 OAF-TSA ______ Statistical Analysis of Thesis and Student Research Projects _________________________________ 182 OAF-TSS _______ Medical Applications of Mass Spectrometry ______________________________________________ 184 4th Semester OAE-2DA ______ Two-Dimensional Anatomy - Modern Medical Imaging Techniques ___________________________ 186 OAE-BSK ______ Bioinorganic Chemistry ______________________________________________________________ 188 OAE-EAH ______ Physiology of the Adaptation Limits of the Human Body ____________________________________ 190 OAE-H4A ______ Medical Hungarian 4A - Basics of Medical Communication _________________________________ 192 OAE-H4B ______ Medical Hungarian 4B - Medical Communication in Practice ________________________________ 194 OAE-MPS ______ Medizinische Psychologie und Soziologie________________________________________________ 196 OAE-SEX ______ Sexology __________________________________________________________________________ 199 OAE-TIZ _______ Central Regulation of Feeding and Metabolism. New Approaches _____________________________ 201 OAF-ANC ______ Medical English 2/c - Writing Up Research - How to Prepare and Read Medical Journal Articles ____ 203 OAF-BDK ______ Molecular Biological Methods in Cancer Research_________________________________________ 205 OAF-BIN _______ Bioinformatics _____________________________________________________________________ 207 OAF-BOT ______ Theory and Practice of Evidence-based Medicine __________________________________________ 209 OAF-CSU ______ Miracles of Living Materials („Realistic” Biochemistry) ____________________________________ 211 OAF-EKK ______ Health and Physical Environment ______________________________________________________ 213 OAF-EMM _____ Molecular Basis of Endocrine Diseases __________________________________________________ 215 OAF-EUP ______ Managing Successful EU Projects ______________________________________________________ 217 3 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EXT ______ Extraction and Chromatographic Techniques in Medicinal Plant Analysis ______________________ 219 OAF-JAV _______ Signal Transduction _________________________________________________________________ 221 OAF-MAF ______ Relationship Between Intrauterine Development and Anatomical Situs _________________________ 223 OAF-MC2 ______ Methods in Molecular Cell Biology II ___________________________________________________ 224 OAF-MEA ______ Poisonous and Venomous Animals, Animal Poisonings _____________________________________ 226 OAF-MMR _____ Nuclear Magnetic Resonance for Dummies ______________________________________________ 228 OAF-MRK ______ Molecular and Cellular MR Imaging ____________________________________________________ 230 OAF-OBQ ______ Medical Biochemistry - Questions and Answers ___________________________________________ 232 OAF-PCS _______ Bone Pathology ____________________________________________________________________ 234 OAF-TD2 _______ Student Project Research 2____________________________________________________________ 237 OAF-TKE ______ The Ethics of Scientific Research ______________________________________________________ 238 OAF-VAA ______ Iron Metabolism: from Molecular Mechanisms to Clinical Consequences _______________________ 240 OAF-VSP _______ Urinary Steroid Profiles ______________________________________________________________ 241 5th Semester OAE-ABE ______ Inborn Errors of Metabolism __________________________________________________________ 243 OAE-COP ______ Pathophysiology of Chronic Obstructive Lung Diseases (COPD) _____________________________ 245 OAE-IM1 _______ Immunpathology 1 __________________________________________________________________ 247 OAE-IMG ______ Immunological Techniques in Laboratory Practice _________________________________________ 249 OAE-KK1 ______ Clinical Pathophysiology 1 ___________________________________________________________ 251 OAE-TD3 ______ Student Project Research 3____________________________________________________________ 253 OAF-DIM ______ Immunology of the Skin______________________________________________________________ 254 OAF-EAF ______ Development and Malformations of the Human Cerebral Cortex ______________________________ 256 OAF-EVO ______ Evolutionary Immunobiology _________________________________________________________ 258 OAF-GMK ______ Qualitative and Quantitative Analysis of Drugs from Human Tissue ___________________________ 259 OAF-HIF _______ The Anatomy, Physiology, Development and Pathology of the Hippocampal Formation ___________ 261 OAF-KUO ______ Medical Humanities _________________________________________________________________ 263 OAF-MME _____ Molecular Medicine _________________________________________________________________ 265 OAF-MOD ______ Molecular Diagnostics _______________________________________________________________ 267 OAF-MOT ______ Molecular Therapies_________________________________________________________________ 269 OAF-N27 _______ Clinical Hungarian 1 ________________________________________________________________ 271 OAF-NMN ______ Neuroimaging Methods in Neuropsychological Research ____________________________________ 273 OAF-PRB ______ Protein Biotechnology _______________________________________________________________ 274 ATT5 __________ Physical Education 5 ________________________________________________________________ 276 6th Semester OAE-ASZ ______ The Antimicrobial Drugs and their Clinical Use ___________________________________________ 277 OAE-FAJ _______ Pain and Analgesics _________________________________________________________________ 279 OAE-FBE ______ Causes of Expansion and Preventive Methods in Infectious Diseases __________________________ 281 OAE-GER ______ Basics of Gerontology _______________________________________________________________ 283 OAE-KK2 ______ Clinical Pathophysiology 2 ___________________________________________________________ 285 OAE-KLP ______ Clinicopathology ___________________________________________________________________ 287 OAE-KMT ______ Case Reports in Clinical Microbiology __________________________________________________ 289 OAE-MAO _____ Behavioral Medicine ________________________________________________________________ 291 OAE-NDG ______ Neurological Differential Diagnosis ____________________________________________________ 293 OAE-TD4 ______ Student Project Research 4____________________________________________________________ 294 OAE-TFS _______ Performance-enhancing Drugs. Physiology, Pharmacology and Clinical Aspects _________________ 295 OAF-AMM _____ Introduction and Basics of Operational Medicine __________________________________________ 297 OAF-DRH ______ Microbiology Cases of House M.D. ____________________________________________________ 299 OAF-EMV ______ Microbiological Aspects of Food Safety _________________________________________________ 301 OAF-IVF _______ Infections and Immunity _____________________________________________________________ 303 OAF-KPR ______ Chemoprevention ___________________________________________________________________ 305 OAF-LLA ______ A Spectacle of Vision________________________________________________________________ 307 OAF-MST ______ Microsurgical Techniques ____________________________________________________________ 309 OAF-N28 _______ Clinical Hungarian 2 ________________________________________________________________ 310 OAF-VAE ______ Pathophysiology of Blood Cells________________________________________________________ 312 4 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 7th Semester OAE-AAN ______ General Anaesthesia _________________________________________________________________ 314 OAE-AE1 ______ Anaesthesia 1 ______________________________________________________________________ 316 OAE-DGH ______ Diagnostic Methods in Gastroenterology and Hepatology ___________________________________ 317 OAE-DON ______ Depression and Suicide - Clinical and Research Approach ___________________________________ 319 OAE-GST ______ Special Fields of Pharmacology ________________________________________________________ 320 OAE-IDR _______ Biophysical Background and Clinical Application of Isotopdiagnostic and Radiotherapeutic Methods 322 OAE-KKM _____ Complex Pathophysiological Mechanisms _______________________________________________ 324 OAE-KOE ______ Case-reports: Pathophysiological Analyses _______________________________________________ 326 OAE-PSA ______ Psychosomatic Approach in Medicine ___________________________________________________ 327 OAE-TUO ______ Symptom-Based Diagnostics in Internal Medicine _________________________________________ 329 OAF-DEP ______ Anxiety, Depression and Somatization in General Medical Practice ___________________________ 331 OAF-EDM ______ Epidemiological Methods for Undergraduate Research (TDK) and Thesis-writing ________________ 332 OAF-FMA ______ Data Analysis 1 ____________________________________________________________________ 334 OAF-FM2 ______ Data Analysis 2 ____________________________________________________________________ 336 OAF-GIP _______ Child and Adolescent Psychiatry _______________________________________________________ 338 OAF-HTI _______ Efficient Thesis Writing ______________________________________________________________ 340 OAF-IFZ _______ Neurodevelopmental Disorders ________________________________________________________ 342 OAF-MIA ______ Current Hot Topics in Medical Microbiology _____________________________________________ 344 OAF-RAR ______ Immunological Basis of Rheumatoid Arthritis (RA) ________________________________________ 346 OAF-SFO _______ Specialties in Otolaryngology _________________________________________________________ 347 OAF-THM ______ Thermomania: the Medicine of Thermoregulation _________________________________________ 349 8th Semester OAE-ATE ______ Anaesthetic Techniques ______________________________________________________________ 352 OAE-GCT ______ Practical Ultrasound and CT Diagnostics ________________________________________________ 353 OAE-GIO _______ Angiology _________________________________________________________________________ 355 OAE-GLM ______ Practices in Laboratory Medicine ______________________________________________________ 357 OAE-GNU ______ Child Neurology ____________________________________________________________________ 358 OAE-KFA ______ Clinical Pharmacology _______________________________________________________________ 360 OAE-NKD ______ Modern Cardiovascular Diagnostics and Therapy __________________________________________ 362 OAE-OIN _______ Medical Informatics _________________________________________________________________ 364 OAE-POF ______ Problem-based Pharmacology _________________________________________________________ 366 OAE-TRO ______ Tropical Medicine __________________________________________________________________ 368 OAF-ERM ______ Vascular Surgery Techniques _________________________________________________________ 370 OAF-FBJ _______ Dental and Oral Diseases in General Medicine ____________________________________________ 371 OAF-GTH ______ Gene Therapy ______________________________________________________________________ 373 OAF-HAS ______ Abdominal Surgery Techniques ________________________________________________________ 375 OAF-IOH _______ Forensic Medicine: New Challenges - Modern Frontiers ____________________________________ 376 OAF-MIS _______ Laparoscopic Surgery Techniques ______________________________________________________ 378 OAF-REG ______ Medical Rehabilitation and Physical Medicine; Basics of Theory and the Daily Practice ___________ 379 OAF-SUB ______ Radiation Biology __________________________________________________________________ 381 9th Semester OAE-CUI _______ Current Issues and New Surgical Techniques _____________________________________________ 383 OAE-GEP ______ Basic Practical Principles of Joint Replacement ___________________________________________ 385 OAE-HTK ______ Advanced Level Traumatology Manual Skill Course _______________________________________ 387 OAE-OES ______ Endoscopic Surgery of the Nasal Cavities and Paranasal Sinuses ______________________________ 389 OAE-ORS ______ Specialities in Orthopaedics ___________________________________________________________ 391 OAE-PTS _______ Management of Severely Injured Patients - Simulation-based Clinical Skills Practice _____________ 392 OAE-SUO ______ Emergency Medicine ________________________________________________________________ 394 OAE-SUP ______ Emergency Psychiatry _______________________________________________________________ 396 OAF-FHB ______ Otology and Temporal Bone Dissection _________________________________________________ 398 OAF-MUE ______ Migration Health and Travel Medicine __________________________________________________ 400 OAF-SFT _______ Emergency-cases in Ophthalmology, Ophthalmoscopy _____________________________________ 402 OAF-SSA _______ Cardiac and Thoracic Surgery Anesthesia ________________________________________________ 403 5 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 10th Semester OAE-GYS ______ Paediatric Surgery __________________________________________________________________ 405 OAE-IDE _______ Neurosurgery ______________________________________________________________________ 407 OAE-MKF ______ Neurosurgical Treatment of Neurogenic Pain and Movement Disorders ________________________ 410 OAE-NEG ______ Neurological Differentialdiagnosis, Rare Neurological Diseases, Neurogenetics__________________ 411 OAE-NKE ______ Clinical Cases: Nephrology, Diabetology, Hypertension ____________________________________ 413 OAE-NKT ______ High-Risk Pregnancy ________________________________________________________________ 414 OAE-NTR ______ Neurotraumatology _________________________________________________________________ 416 OAE-UEA ______ Neonatal Care in the Delivery Room (Adaptation) _________________________________________ 418 6 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-BFA PHYSICAL BASIS OF BIOPHYSICS DR. EMŐKE BÓDIS, assistant professor Department of Biophysics Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ both semesters semester ▪ recommended semester: 1 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 25 Prerequisites: no prerequisites Topic The course addresses the chapters of physics which are necessary for a proper understanding of Biophysics (lecture and practicals). Beyond theoretical discussions, example problems are solved. Conditions for acceptance of the semester Maximum 3 absence is allowed. Mid-term exams Making up for missed classes There is no option. Reading material - Obligatory literature - Literature developed by the Department - Notes Course related information can be found on the website of the Department of Biophysics (http://biofizika.aok.pte.hu). - Recommended literature As a base, any secondary school physics book is useful. Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 Mathematical basics. Scalars and vectors Physical quantities and units Newton’s laws Conservation of momentum. Collisions Motion on a straight line. Kinetics Motion on a straight line. Dynamics Circular motion, rotation Oscillations Work and energy. Friction The work-energy theorem. Conservation of mechanical energy Hydrostatics Hydrodynamics First and second law of thermodynamics Thermodynamic potentials Electrostatics Ohm`s law, Kirchhoff`s laws Magnetostatics Magnetic induction Waves Wave- and geometrical optics Atom- and nuclear physics Radioactivity Radiations (radioactive, electromagnetic) Electromagnetic waves Radiation-matter interaction Special radiation-matter interactions 7 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 27 28 Test writing Test writing Exam topics/questions Can be found on the website of the Department of Biophysics (http://biofizika.aok.pte.hu) Participants Dr. Bódis Emőke (BOEAAD.T.JPTE), Dr. Szabó-Meleg Edina (MEEDAA.T.JPTE), Dr. Talián Csaba Gábor (TACRAAO.PTE), Kollár Veronika Tünde (KOVGACT.PTE), Leipoldné Vig Andrea (VIAFAAO.PTE), Szatmári Dávid (SZDHAAT.PTE), Tóth Mónika Ágnes (TOMIAAT.PTE) 8 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-BO1 BIOPHYSICS SEMINARS 1 DR. ANDRÁS SZILÁRD LUKÁCS, assistant professor Department of Biophysics Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 40 Prerequisites: OAA-BI1 parallel Topic The objective of the course is to advance the acquisition of knowledge and skills related to Biophysics 1. Object-oriented discussions and problem solving sessions are organized in interactive small-group seminars. Conditions for acceptance of the semester Maximum of three absences. Mid-term exams Making up for missed classes None. Based on previous agreement with the lecturer the student can attend the seminar with another group another day on the same week. Reading material - Obligatory literature - Literature developed by the Department http://biofizika.aok.pte.hu - Notes Damjanovich et al (ed.): Medical Biophysics - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction Diffusion Osmosis. Fluid flow Circulation. Cardiac biophysics. Protein folding Resting membrane potential. Sensory receptors. Action potential Vision. Hearing Cytoskeleton. Motor proteins Structure of striated muscle. Molecular basis of muscle function Foundations of thermodynamics. Laws of thermodynamics Thermodynamic potentials The double nature of light. The structure of the atoms Quantum numers. Spin. Molecular orbitals Laser. X-ray Test writing Exam topics/questions Can be found on the departmental website: http://biofizika.aok.pte.hu Participants Dr. Kengyel András Miklós (KEAFACO.PTE), Dr. Szabó-Meleg Edina (MEEDAA.T.JPTE), Futó Kinga (FUKIAAT.PTE), Huber Tamás (HUTEAB.T.JPTE), Kollár Veronika Tünde (KOVGACT.PTE), Szatmári Dávid (SZDHAAT.PTE) 9 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-H1A MEDICAL HUNGARIAN 1A - COMMUNICATION SKILLS DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OAE-H1B parallel Topic To establish basic skills in reading, writing, listening and speaking Hungarian in preparation for effective medical communication. Conditions for acceptance of the semester Participation in class work is obligatory. In case absences exceed 25% of total class time, the course will be regarded as uncompleted. In the case of absences up to 25% of total class time, oral examination will have to be taken Mid-term exams Making up for missed classes To be discussed with the course tutor in each individual case. Reading material - Obligatory literature - Literature developed by the Department In-house course book: at the homepage of the institute: http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Greeting people, formality and informality Greeting people, formality and informality Addressing people, men and women Addressing people, men and women Starting conversation, the elderly and children Starting conversation, the elderly and children Introducing, equal and unequal relations Introducing, equal and unequal relations Nutritional History Taking Nutritional History Taking Nutrients Nutrients Consolidation Test 1 Health Preservation, Sports, Addictions Health Preservation, Sports, Addictions Writing CV, occupation, work Medical Specialties, Consulting Room and Ward Medical Specialties, Consulting Room and Ward Telling CV, family relations Introducing family Introducing family Describing people - Internal and external features Describing people - Internal and external features Health care institutions, consolidation Health care institutions, consolidation Test 2 Course Evaluation 10 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Two written test papers and oral presentations Participants Dr. Hegedűs Anita (HEAAAA.B.JPTE), Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE), Dr. Warta Vilmos (WAVEAB.B.JPTE), Eklicsné Dr. Lepenye Katalin (EKLAXA.B.JPTE), Hamarné Sávay Judit (HASMAAO.PTE), Hild Gabriella (MAGAAD.B.JPTE), Horváth Lilla Anita (HOLFABP..PTE), Kurdiné Molnár Eszter (KUMPAAK.PTE), Lokodiné Szolcsányi Judit (LOSIAAB.PTE), Mészégetőné Halmos Éva (MEHHABE.PTE), Ronczykné Berta Anikó (BEAAAI.B.JPTE), Szántóné Csongor Alexandra (CSAAAA.B.JPTE), Tóth Ida (TOIHABE.PTE), Váradi Katalin (VAKHAAE.PTE) 11 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-H1B MEDICAL HUNGARIAN 1B - LANGUAGE POINTS DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OAE-H1A parallel Topic Familiarizing foreign students with basic paradigms used in specific conversations. Conditions for acceptance of the semester Participation in class work is obligatory. In case absences exceed 25% of total class time, the course will be regarded as uncompleted. In the case of absences up to 25% of total class time, oral examination will have to be taken Mid-term exams Making up for missed classes Participation is obligatory. Reading material - Obligatory literature - Literature developed by the Department http://aok.pte.hu/index.php?page=egyseg&egy_id=60&menu=okt_anyag&nyelv=eng - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Basics of Hungarian Phonetics and Morphology Basics of Hungarian Phonetics and Morphology Personal Pronouns - formal and informal style Personal Pronouns - formal and informal style Constructing Questions - Question Words Constructing Questions - Question Words Numerals - Cardinal, Ordinal, Labels Numerals - Cardinal, Ordinal, Labels Verbs - Definite and Indefinite Conjugation Verbs - Definite and Indefinite Conjugation Expressing Frequency Expressing Frequency Test 1 Articles Modality - necessity Modality - necessity Objective Case Objective Case Verbal prefixes Verbal prefixes Expressing Time Expressing Time Expressing Location - Trinity of Directions Expressing Location- Trinity of Directions Dative Case Dative Case Test 2 Course Evaluation 12 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Participants Dr. Hegedűs Anita (HEAAAA.B.JPTE), Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE), Dr. Warta Vilmos (WAVEAB.B.JPTE), Eklicsné Dr. Lepenye Katalin (EKLAXA.B.JPTE), Hamarné Sávay Judit (HASMAAO.PTE), Hild Gabriella (MAGAAD.B.JPTE), Horváth Lilla Anita (HOLFABP..PTE), Kurdiné Molnár Eszter (KUMPAAK.PTE), Lokodiné Szolcsányi Judit (LOSIAAB.PTE), Mészégetőné Halmos Éva (MEHHABE.PTE), Molnár Annamária (MOAF-AC.B.JPTE), Ronczykné Berta Anikó (BEAAAI.B.JPTE), Szántóné Csongor Alexandra (CSAAAA.B.JPTE), Váradi Katalin (VAKHAAE.PTE) 13 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-MS1 EXPERIMENTS IN MOLECULAR CELL BIOLOGY 1 DR. JÓZSEF SZEBERÉNYI, professor Department of Medical Biology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 14 lectures + 0 practices + 14 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 80 Prerequisites: no prerequisites Topic The main objectives of this course are to stimulate interest in students toward the experimental approach to cell biology, to develop their interpretation, problem-solving skills and their creative way of thinking. This is an advanced course tightly connected to the compulsory subject Molecular Cell Biology. The lectures cover the important discoveries of cell and molecular biology, using an experimental approach. On the small-group-discussions phenomena of molecular cell biology are described and discussed using problem-based learning techniques (e.g. figure analysis, planning of experiments, application tests) developed in the Department of Medical Biology. The compulsory subject deals with these same topics with more conventional educational methods. Although the course helps to understand principles and processes in cell biology, it is in no way required to successfully complete the compulsory subject. Conditions for acceptance of the semester According to the Code of Studies. Mid-term exams Making up for missed classes None. Reading material - Obligatory literature - Literature developed by the Department Educational materials on the homepage of the Department of Medical Biology: Problem-solving tests in molecular cell biology Figure analysis in molecular cell biology - Notes - Recommended literature Cooper-Hausman: The Cell. A Molecular Approach Szeberényi J.: Experiments in Molecular Cell Biology Lectures 1 1 2 3 4 5 6 7 8 9 Methods to study cell defense mechanisms Dr. Szeberényi József Educational objectives of the course Dr. Szeberényi József Methods of morphology Dr. Szeberényi József Methods to study gene structure Dr. Szeberényi József Methods to study gene function Dr. Szeberényi József Methods to study the chromatin Dr. Szeberényi József Methods to study the cell cycle Dr. Szeberényi József Methods to study DNA synthesis Dr. Szeberényi József Methods to study RNA synthesis Dr. Szeberényi József Test Dr. Szeberényi József 14 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 10 11 12 14 Methods to study protein synthesis Dr. Szeberényi József Methods to study gene regulation Dr. Szeberényi József Methods to study vesicular transport Dr. Szeberényi József Final test Dr. Szeberényi József Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Description of problem-solving exercises used in the course Examples for the use of radioactive and non-radioactive labeling Examples for the use of separation techniques Examples for the analysis of DNA Examples for the analysis of chromatin Examples for the analysis of the cell cycle Examples for the analysis of DNA replication and repair Examples for the analysis of transcription and RNA processing Test Examples for the analysis of translation Examples for the analysis of gene regulation Examples for the analysis of secretion and endocytosis Examples for the analysis of cell defense Final test Exam topics/questions Multiple-choice test. Participants Dr. Bátor Judit (BAJFAAO.PTE), Dr. Berta Gergely (BEGFADO.PTE), Dr. Kemény Ágnes (KEAAAA.T.JPTE), Dr. Pap Marianna (PAMFAAO.PTE), Harci Alexandra (HAAGABT.PTE), ifj. Dr. Sétáló György (SEGMAAO.PTE), Németh Mária (NEMGAAT.PTE), Schipp Renáta (SCRDAA.T.JPTE), Varga Judit (VAJGACT.PTE) 15 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-N06 MEDICAL TERMINOLOGY GABRIELLA HÁBEL, language teacher Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 14 lectures + 0 practices + 14 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 250 Prerequisites: no prerequisites Topic Introduction into the basics of Medical Terminology pertaining to Anatomy and clinical aspects focusing on word building and breaking down medical terms. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes To be discussed with the instructor. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature University Script Donáth, Tibor: Lexicon Anatomiae. Anatomical Dictionary, Semmelweis, Bp. 1999 Barbara Janson Cohen: Medical Terminology, Wolters Kluwer, Lippincott Williams and Wilkins, Baltimore 2008 This resource is also available via thePoint (http://thepoint.lww.com/cohen5e) Jean Tannis Dennerll: Medical Terminology Made Easy, Delmar Publishers Inc., New York 1991 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Introduction into Medical Terminology. The importance of Medical terminology in practice. Hábel Gabriella The human body. Technical language use pertaining to anatomy and clinical practice. Hábel Gabriella Termini and clinical references pertaining to the digestive system Hábel Gabriella Termini pertaining to the respiratory system Hábel Gabriella The heart. Terminology pertaining to cardiology. Hábel Gabriella Terminology pertaining to blood and lymphatic system Hábel Gabriella Terminology pertaining to the genito-urinary system Hábel Gabriella Anatomical and clinical references pertaining to the genital organs Hábel Gabriella Sensory perception and its terminology Hábel Gabriella Characteristics of the technical language use pertaining to the brain and nervous system Hábel Gabriella Terms pertaining to bones, muscles, joints, ligaments and the relevant traumas Hábel Gabriella Terms pertaining to dentistry. Anatomy of the teeth and clinical aspects Hábel Gabriella 16 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Comparison of anatomical and clinical language usages based on authentic examples Hábel Gabriella Test paper Hábel Gabriella Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction. Structure of Medical Terminology. Features of anatomical and clinical language usages. Parts of the human body. Anatomical directions, plates. Introduction into the terminology pertaining to the digestive system, diagnoses. Characteristics of the terminology pertaining to the respiratory system. Case studies from the field of pulmonology. About the heart in nutshell. Symptoms, diagnoses, procedures in the field of cardiology. Basic termini and diseases pertaining to blood and lymphatic system. Test paper Basic termini pertaining to the genito-urinary system. Diagnostic features of nephrology and urology. Anatomical designations pertaining to the genitalia. Diagnostic methods, procedures, interventions in the fields of gynaecology and andrology. Sensory perception. Diagnostic procedures, making diagnosis in the fields of dermatology, ophthalmology and otorhinolaryngology. Termini pertaining to the brain and neurology. Disorders of the brain, diagnoses in the field of neurology. Bones, muscles, articulations, ligaments. Introduction into the language of traumatology Termini pertaining to dentistry. Anatomical and clinical expressions pertaining to the buccal cavity. Introduction into the technical language of pharmaceutics Exam topics/questions Participants Hábel Gabriella (HAGTAAP.PTE) 17 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-ORE MEDICAL REHABILITATION IN DAILY PRACTICE Course director: DR. GÉZÁNÉ SARLÓS (DR. CECILIA SARLÓS), assistant professor Department of Immunology and Rheumatology 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 1 Number of hours/semester: 7 lectures + 7 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 80 Prerequisites: no prerequisites Topic Are you interested in what is happening with Michael Schumacher? How could be managed a child or an adult patient living in wheelchair or patient with visual impairment, or deaf? How could be their life better? This course focuses on practical knowledge in medical rehabilitation, the different problems and possibilities of patients with disabilities. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Short test exam Making up for missed classes As agreed with the course director. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Journal of Rehabilitation Medicine - http://www.medicaljournals.se/jrm/content/ White Book on Physical and Rehabilitation Medicine in Europe Essential Physical Medicine and Rehabilitation (Grant Cooper) Lectures 1 2 3 4 5 6 7 Problems and possibilities of children or adult patients living in wheelchair. Possibilities of occupational rehabilitation, family planning and driving car. Dr. Cserháti Péter Psychosocial development of patients with visual impairment, or deaf and possibilities of their rehabilitation (Detre Imola) Dr. Sarlós Gézáné Rehabilitation of patients with osteoarthritis, spondylitis, ankylosing spondylitis and osteoporosis. Different types of the physical therapy. Home nursing aids Dr. Sarlós Gézáné Rehabilitation of neurologic patients after stroke, brain or spinal injury Dr. Vajdáné Dr. Tasnádi Emese Pediactic rehabilitation. Problems and possibilities of patients with cerebral palsy (Dr. Lővei Csilla) Dr. Vajdáné Dr. Tasnádi Emese Cardiac rehabilitation. Cardiac rehabilitation programs after a heart attack or after surgery Dr. Nyárfás Géza Rehabilitation of patients with psychologic diseases and the practice of treating addictions Dr. Szemelyácz János Practices 1 2 3 4 Case reports with patients living in wheel chairs Psychosocial development and rehabilitation of patients with visual impairment, or deaf (Detre Imola) Different types of the physical therapy. Home nursing aids Demonstration: rehabilitation post severe brain injury 18 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 5 6 7 Demonstration: rehabilitation of children Cardiac rehabilitation programs after a heart attack or after surgery The practice of treating addictions Seminars Exam topics/questions Participants Dr. Cserháti Péter (CSPXXXXX.PTE), Dr. Nyárfás Géza (NYGPAAP.PTE), Dr. Sarlós Gézáné (VACPAAP.PTE), Dr. Szemelyácz János (SZJIAAE.PTE), Dr. Vajdáné Dr. Tasnádi Emese (TAEAAA.B.JPTE) 19 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-OTT HISTORY OF MEDICINE DR. CSILLA RÚZSÁS, associate professor Department of Immunology and Biotechnology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ both semesters semester ▪ recommended semester: 1 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 80 Prerequisites: no prerequisites Topic The purpose of the course is to give an opportunity for reviewing the progress in medicine historically, from the ancient times up to the present époque, on the basis of cultural background. The understanding of the fact that the contemporary medicine is the result of the efforts of several centuries will be hopefully stimulatory for the students in the professional improvement, realizing that both the theoretical basis and healing practice are due to the devoted work of previous generations. Accordingly, the progress from healing art to healing science will be illustrated in relation to the culture of previous centuries. Since the students of our University come from countries of different cultures and traditions, the progress in medicine of ancient Greek and Persian and Islamic culture are equally reviewed, besides the European medicine where English and German relations are of outstanding importance, as reflected by the fact that in German universities, high number of weekly hours are devoted for the history of medicine. Accordingly, the most outstanding physicians and clinical schools, playing a prominent role in the European progress will be reviewed. Our aim is to demonstrate that each culture represents a value which contributes to the common treasure of humanity. Conditions for acceptance of the semester Survey of the theoretical basis of medical practice in a historical period. Mid-term exams Written essay surveying the medical practice and theory of a selected historical period. (2-4 pages) Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department Summary of the content of each lecture (detailed description of authors and the main outlines of their activity promoting the medicine) - Notes - Recommended literature Delano: The Story of Medicine, London Benke J.: Az orvostudomány története - Hungarian ed. with English summary, Medicina, Bp. 2008. Lectures 1 2 3 4 5 6 7 8 9 10 Archaic medicine Dr. Rúzsás Csilla Ancient Egypt, Mesopotamia, India, traditional Chinese medicine Dr. Rúzsás Csilla Medicine in Greece in the Antiquity Dr. Rúzsás Csilla The most outstanding medical schools; Hippocratic medicine Dr. Rúzsás Csilla Medicine in the Roman times. Galen. Dr. Rúzsás Csilla Byzantine leading doctors Dr. Rúzsás Csilla Early medieval medicine in Europe Dr. Rúzsás Csilla Monasteric medicine in medieval Europe Dr. Rúzsás Csilla The medicine under Islam Dr. Rúzsás Csilla The most outstanding physicians of Arabic-Islamic medicine Dr. Rúzsás Csilla 20 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Foundation of the universities in the Middle-Age Dr. Rúzsás Csilla Scholastic medicine Dr. Rúzsás Csilla Medicine in the Renaissance Dr. Rúzsás Csilla Vesal. Paracelsus. Dr. Rúzsás Csilla Medicine of the 17th century: the golden age of sciences Dr. Rúzsás Csilla Raise of natural sciences. Iatrophysics and iatrochemistry Dr. Rúzsás Csilla The age of the 18th century Dr. Rúzsás Csilla The age of enlightment. Progress in pathology. Dr. Rúzsás Csilla Beginnings of modern medicine in the 19th century Dr. Rúzsás Csilla Medical schools in Europe Dr. Rúzsás Csilla Specialisation in medicine in the 19th century Dr. Rúzsás Csilla New approaches and equipment in medicine of the 19th century Dr. Rúzsás Csilla Medicine in the first half of the 20th century Dr. Rúzsás Csilla Results of Nobel-Prize winners in medicine Dr. Rúzsás Csilla Main trends in medicine in the second half of the 20th century Dr. Rúzsás Csilla Molecular biological methods in modern medicine and related problems Dr. Rúzsás Csilla The history of the University of Pécs Dr. Rúzsás Csilla Relations with prominent European scientists Dr. Rúzsás Csilla Practices Seminars Exam topics/questions Possible themes for the essays: Characteristics of the ancient Egyptian and Mesopotamian culture. Medicine of ancestral Chinese civilization. Medicine of Greece in the Antiquity. Hippocratic medicine and the Hippocratic Collection. Post-hippocratic medicine: The school of Athens and Alexandria. Outstanding physicians of Persian and Arabic-Islamic medicine. Medical education in the Middle-Ages. The main epidemies in Europe. The most prominent physicians in the Renaissance. Main trends in medicine of the 19th century. Ignatz Semmelweis, the saver of the mothers. Most important discoveries in medicine in the 20th century. Participants 21 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-BAL MINERAL AND SPA WATERS, BALNEOLOGY DR. CSABA VARGA, associate professor Department of Public Health Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5– Prerequisites: no prerequisites Topic The main educational task of the subject initiating to form state-of-art regarding use and application of mineral and spa waters in Hungary and EU with special respect of the prevention. Short description of the course: Delivering up to date hydrological, hydrogeological, physical, chemical, biological knowledge for students of medicine and other sciences. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Written exam. Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department Coospace - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Hydrogeology and balneology of mineral and spa waters Dr. Varga Csaba Hydrogeology of Hungarian mineral and spa waters Dr. Varga Csaba Correlation of the geological characteristics and the chemical composition Dr. Varga Csaba Hydrology of mineral and spa waters Dr. Varga Csaba Mineral and spa waters in Hungary and Europe Dr. Varga Csaba Chemical characteristics of mineral and spa waters Dr. Varga Csaba Inorganic analytical classification Dr. Varga Csaba Presence of microelements Dr. Varga Csaba Inorganic ions, substances and complexes in the therapeutical effect Dr. Varga Csaba Organic ions, substances and complexes in the therapeutical Dr. Varga Csaba In situ water analysis Dr. Varga Csaba Inorganic analysis Dr. Varga Csaba Hygienic microbiological analysis Dr. Varga Csaba Artificial mineral and medicinal waters Dr. Varga Csaba 22 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Peloids: genesis, chemical/physical/toxicological properties. Hungarian peloids. Dr. Varga Csaba Mineral and spa water products Dr. Varga Csaba Introduction to Balneology: objectives and history Dr. Varga Csaba Water and ions in the human body Dr. Varga Csaba External cure with spa waters, mode of action Dr. Varga Csaba Mechanic, thermal, chemical and psychic actions, Spa reaction. Dr. Varga Csaba Water types in cure Dr. Varga Csaba Application of spa waters to different diseases Dr. Varga Csaba Therapeutic applications of peloids Dr. Varga Csaba Internal use of mineral and medicinal waters. Drinking cure Dr. Varga Csaba Inhalation cure Dr. Varga Csaba Other natural cures: climate cure, physicotherapy, additional therapies Dr. Varga Csaba Exam Dr. Varga Csaba Exam Dr. Varga Csaba Practices Seminars Exam topics/questions CooSpace Participants 23 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-BBM INTRODUCTION TO BIOMETRICS DR. LÁSZLÓ PÓTÓ, associate professor Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 1 Number of hours/semester: 0 lectures + 14 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 20 Prerequisites: no prerequisites Topic Exploring data (using graphs and numbers) are usually handled as one-lesson „first chapter” by basic statistical courses. This is, because a first course in statistics introduces many new skills. It also introduces some new ideas, that all are „hard to understand” for students. The new approach is to make a solid foundation to learn statistics by a more thorough introduction to those: The course tries to make clear a few of these fundamental ideas of statistics - limited to understanding and working with data. An improved skill for exploring data is useful not only at your classes and your future job but in the everyday life as well. Conditions for acceptance of the semester Active participation at the classes; maximum one missed class. Mid-term exams Active participation at the classes; maximum one missed class. Making up for missed classes One extra class Reading material - Obligatory literature - Literature developed by the Department - Notes László Pótó: Biometrics, workbook, Pécs, 2007. - Recommended literature 1, Moore, D. S.: The Basic Practice of Statistics, 5th edition, 2010. 2, Moore, David S., McCabe, George P.: Introduction to the Practice of Statistics, 5th edition, W.H. Freeman, 2005 and Yates, Dan, Moore, David S., Starnes, Daren S.: The Practice of Statistics (TI-83/89 Graphing Calculator Enhanced) 2/e, W.H. Freeman, 2003 or 3, Rees, W. G.: Essential Statistics, Chapman and Hall, 1992 Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Probability examples 1 Probability examples 1 Probability examples 2 - discrete distributions Probability examples 2 - discrete distributions Exploring data by graphs - 1 Exploring data by graphs - 1 Exploring data by graphs - 2 Exploring data by graphs - 2 Exploring data by numbers - sample measures 1 Exploring data by numbers - sample measures 1 Exploring data by numbers - sample measures 2 Exploring data by numbers - sample measures 2 The normal distribution The normal distribution Seminars Exam topics/questions No exam - but active participation on the classes is a must. 24 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Participants Dr. Pótó László (POLGABO.PTE) 25 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-BFM PROBLEM SOLVING IN BIOMETRICS DR. LÁSZLÓ PÓTÓ, associate professor Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 1 Number of hours/semester: 0 lectures + 14 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 20 Prerequisites: no prerequisites Topic Give a chance to have more practice to solve problems in Biometrics using PC and the SPSS software in the computer room. This was a regular need of the students earlier since the special way how a MD should handle the typical medical problems (special way of thinking) was not founded by the secondary school education. This foundation is an important focus point of the Biometrics course. It seems, the weekly 1+1 lectures were not enough for most of the students for completing this important goal: To develop some brand new skills. This course offers an organized way for that extra practices. It offers also some „brushing up” chances for those who has completed Biometrics earlier. Conditions for acceptance of the semester Active participation on the classes Maximum one missed class Mid-term exams Active participation on the classes Making up for missed classes One extra class Reading material - Obligatory literature - Literature developed by the Department - Notes László Pótó: Biometrics, workbook, Pécs, 2007. - Recommended literature 1, Moore, D. S.: The Basic Practice of Statistics, 5th edition, 2010. or 2, Moore, David S., McCabe, George P.: Introduction to the Practice of Statistics, 5th edition, W.H. Freeman, 2005 and Yates, Dan, Moore, David S., Starnes, Daren S.: The Practice of Statistics (TI-83/89 Graphing Calculator Enhanced) 2/e, W.H. Freeman, 2003 or 3, Rees, W. G.: Essential Statistics, Chapman and Hall, 1992 Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 The Confidence Interval of the expected value The Confidence Interval of the expected value The one sample (and the paired samples) t test The one sample (and the paired samples) t test The CI and the hypothesis testing - the type one and type two errors. The CI and the hypothesis testing - the type one and type two errors. The independent samples t test The independent samples t test The linear regression The linear regression The contingency tables - the chi squares test The contingency tables - the chi squares test The nonparametric tests The nonparametric tests 26 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions No exam but active participation on the classes is a must. Participants Dr. Pótó László (POLGABO.PTE) 27 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-DME CANCER IS PREVENTABLE! DR. ISTVÁN KISS, professor Department of Public Health Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 26 lectures + 0 practices + 2 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: no prerequisites Topic One of the major challenges for the health care system of the 21st century is the high number of cancer caused deaths. Over the past decades, despite a significant development on the field of medicine, the prognosis of this disease is still not satisfactory. Thus prevention has a key role in in the fight against cancer. The course gives a description on the different types of cancer their major risk factors for a more detailed understanding. Methods of cancer prevention will be described and emphasized – including theoretical knowledge and a practical guide as well. During the course the results of most recent human epidemiological studies on cancer will also be described. Conditions for acceptance of the semester Participation in lectures and practicals is obligatory which is registered. Absences should not exceed 4x45 min. Otherwise signature of grade book is denied. Mid-term exams Written exam. Making up for missed classes There are no make-up classes. Reading material - Obligatory literature - Literature developed by the Department Educational material uploaded on CooSpace. - Notes - Recommended literature Robert Weinberg (ed.): The Biology of Cancer, Garland Science 2006 ISBN 0815340788 Boffetta P., La Veccia: Neoplasms 2009. In Detels R, Beaglehole R, Lansang MA and Gulliford M (eds.) Oxford Textbook of Public Health, 5th ed., Oxfort University Press Lectures 1 2 3 4 5 6 7 8 9 10 Cancer in the 21st century Dr. Kiss István Cancer in developing and developed countries Dr. Kiss István The process of carcinogenesis I Dr. Kiss István The process of carcinogenesis II Dr. Kiss István Characteristics of cancer cells Dr. Kiss István Molecular epidemiology of cancer Dr. Kiss István The most important cancer risk factors in general I Dr. Kiss István The most important cancer risk factors in general II Dr. Kiss István Lung cancer (development, risk factors, prevention) I Dr. Kiss István Lung cancer (development, risk factors, prevention) II Dr. Kiss István 28 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 Colorectal cancer (development, risk factors, prevention) I Dr. Kiss István Colorectal cancer (development, risk factors, prevention) II Dr. Kiss István Breast cancer (development, risk factors, prevention) I Dr. Kiss István Breast cancer (development, risk factors, prevention) II Dr. Kiss István Prostate cancer (development, risk factors, prevention) Dr. Kiss István Head and neck cancer (development, risk factors, prevention) Dr. Kiss István Pancreatic cancer (development, risk factors, prevention) Dr. Kiss István Gastric cancer (development, risk factors, prevention) Dr. Kiss István Liver cancer (development, risk factors, prevention) Dr. Kiss István Cervical cancer (development, risk factors, prevention) Dr. Kiss István Ovarian cancer (development, risk factors, prevention) Dr. Kiss István Skin cancer and melanoma malignum (development, risk factors, prevention) Dr. Kiss István Leukemia (development, risk factors, prevention) Dr. Kiss István Less frequent tumors (development, risk factors, prevention) Dr. Kiss István Genetics, genomics and epigenetics in cancer prevention I Dr. Kiss István Genetics, genomics and epigenetics in cancer prevention II Dr. Kiss István Practices Seminars 1 2 Recommendations I Recommendations II Exam topics/questions CooSpace Participants Dr. Kiss István (KIIFAD.A.JPTE) 29 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-FJE HEALTH PROMOTION DR. ISTVÁN KISS, professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: no prerequisites Topic Health promotion is intimately related not only to preventive medicine, but to the everyday practice of physicians as well. A considerable part of noninfectious diseases is preventable, morbidity and mortality of these illnesses are decreasable by the implementation of effective intervention. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Written exam Making up for missed classes There are no make-up classes Reading material - Obligatory literature - Literature developed by the Department Education material on CooSpace - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Theoretical background of health promotion. Salutogenesis and pathogenesis. Health promotion and health education. Dr. Horváth-Sarródi Andrea Basic documents of health promotion. Dr. Horváth-Sarródi Andrea Methods of health promotion. Measuring of results in health promotion activities. Evidence based health promotion. Dr. Horváth-Sarródi Andrea Health promotion and health policy. Dr. Horváth-Sarródi Andrea Lalonde model. Health in all policies (HiAP). Multisectorality. Stakeholders. Dr. Horváth-Sarródi Andrea Health Impact Assessment (HIA). Dr. Horváth-Sarródi Andrea Health promotion in communities. Effective health promotion in settings (schools, work places, among elderly people) Dr. Horváth-Sarródi Andrea Health planning. Dr. Horváth-Sarródi Andrea Healthy nutrition and health promotion. Dr. Horváth-Sarródi Andrea The role of different types of physical activity in health promotion. Dr. Horváth-Sarródi Andrea Methods of mental health promotion. Promotion of positive mental health and possibilities of prevention of mental disorders. Dr. Horváth-Sarródi Andrea Mental health policy. Dr. Horváth-Sarródi Andrea Role of physicians in the primary, secondary and tertiary levels of prevention. Dr. Horváth-Sarródi Andrea Complex health promotion programs. Examples for effective health promotion activities. Dr. Horváth-Sarródi Andrea 30 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions CooSpace Participants 31 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-GOM POISONOUS MUSHROOMS DR. LORÁND BARTHÓ, professor Department of Pharmacology and Pharmacotherapy Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 70 Prerequisites: no prerequisites Topic Family physicians may play an important role in the early identification and management of mushroom poisoning (MP). This course: - deals with the various types of MP and their symptoms; - molecular mechanisms encountered with the effects of cytotoxic MPs - morphological features of the most important toxic mushrooms/fungi and their edible counterparts. Conditions for acceptance of the semester - Attending at least 75% of the lessons, passing the oral exam - Oral exam includes matters of poisonings, as well as recognizing the most important PMs and their edible counterparts Mid-term exams Exam around week 10 Making up for missed classes Individual Reading material - Obligatory literature - Literature developed by the Department CD prepared by Prof. Barthó - Notes - Recommended literature http://www.rogersmushrooms.com/ Lectures 1 2 3 4 5 6 7 8 9 10 Introduction Dr. Barthó Loránd Introduction Dr. Barthó Loránd Amanitas, Lepiotas (parasols) and their poisonings Dr. Barthó Loránd Amanitas, Lepiotas (parasols) and their poisonings Dr. Barthó Loránd Amanitas, Lepiotas (parasols) and their poisonings Dr. Barthó Loránd Amanitas, Lepiotas (parasols) and their poisonings Dr. Barthó Loránd Other mushrooms with white spores and their p. Dr. Barthó Loránd Other mushrooms with white spores and their p. Dr. Barthó Loránd Other mushrooms with white spores and their p. Dr. Barthó Loránd Other mushrooms with white spores and their p. Dr. Barthó Loránd 32 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Mushrooms with pink, brown or black spores Dr. Barthó Loránd Mushrooms with pink, brown or black spores Dr. Barthó Loránd Mushrooms with pink, brown or black spores Dr. Barthó Loránd Mushrooms with pink, brown or black spores Dr. Barthó Loránd Mushrooms with pink, brown or black spores Dr. Barthó Loránd Mushrooms with pink, brown or black spores Dr. Barthó Loránd Mushrooms with tubes, pores, wrinkles or spines Dr. Barthó Loránd Mushrooms with tubes, pores, wrinkles or spines Dr. Barthó Loránd Molecular mechanisms encountered with the effects of cytotoxic MPs Dr. Szeberényi József Molecular mechanisms encountered with the effects of cytotoxic MPs Dr. Szeberényi József Morels, false morels, puff-balls, corals, etc. Pre-exam Dr. Barthó Loránd Morels, false morels, puff-balls, corals, etc. Dr. Barthó Loránd Some forensic aspects of MPs Dr. Barthó Loránd Muscarine, muscimol, ibotenic acid Dr. Barthó Loránd Coprin, orellanin, aflatoxin Dr. Barthó Loránd Reprise of poisonous mushrooms Dr. Barthó Loránd Reprise of types of poisoning; Exam Dr. Barthó Loránd Exam Dr. Barthó Loránd Practices Seminars Exam topics/questions Oral exam including matters of poisonings, as well as recognizing the most important PMs and their edible counterparts Cytotoxic MPs Gastrointestinal MP Muscarine-type of MP Psychotropic MP Other types of MP Tasks of the general practitioner in case of MP Participants 33 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-KEF PHYSICAL BASIS AND APPLICATION OF MEDICAL IMAGING TECHNIQUES DR. DÉNES LŐRINCZY, professor Department of Biophysics Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 36 Prerequisites: no prerequisites Topic Structure, function and resolution of light and electron microscopes. Generation and spectrum of X-ray, its interaction with matter. Structure of X-ray equipment, image formation, summation effect, contrast. CT, two and three dimensional image formation, resolution, limits of application. Principle of magnetic resonance imaging, interpretation of TR, TE, T1 and T2, as well as their interrelationship. Ultra sound imaging. (According to our actual possibilities there will be picture presentation from the different imaging techniques). Conditions for acceptance of the semester The applicants - in the case of more than one absence (up to maximum three absences in which must not be the consultation or test) should prepare and will be tested from the missed topics given by the instructor. In the case of more than three absences the course can not be accepted. Mid-term exams Making up for missed classes As above Reading material - Obligatory literature - Literature developed by the Department It will be announced at the beginning of the course depending on the possibilities of libraries of Biophysical Department, Faculty of Medicine. A permanent source could be the roaming in the Internet. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 The light. Fermat principle. Dr. Lőrinczy Dénes Basic optics, interference, diffraction. Dr. Lőrinczy Dénes Camera, optics of eye, aberration of image formation. Dr. Lőrinczy Dénes Light microscope, resolution (Abbe). Dr. Lőrinczy Dénes Phasecontrast and polarised microscope. Dr. Lőrinczy Dénes Stereomicroscope. Dr. Lőrinczy Dénes The structure of electronmicroscope, its types, their working principle. Dr. Lőrinczy Dénes Laser tweezers. Dr. Lőrinczy Dénes Atomic force microscope (AFM). Dr. Lőrinczy Dénes Fluorescence microscope. Dr. Lőrinczy Dénes Ultramicroscope. Dr. Lőrinczy Dénes Construction of an X-ray equipment, characteristic of X-ray. Dr. Lőrinczy Dénes Spectrum of X-ray, its interaction with matter. Dr. Lőrinczy Dénes 34 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 X-ray image formation, summation effect, contrast, image amplification. Dr. Lőrinczy Dénes CT, two and three dimensional image formation, resolution. Dr. Lőrinczy Dénes PET, gamma camera. Dr. Lőrinczy Dénes Scintigraphy. Dr. Lőrinczy Dénes Principle of magnetic resonance, the NMR. Dr. Lőrinczy Dénes Principle of magnetic resonance imaging (MRI), limits of application. Dr. Lőrinczy Dénes Interpretation of TR, TE, T1 and T2, as well as their interrelationship. Dr. Lőrinczy Dénes Ultrasound, its medical and biological effects. Dr. Lőrinczy Dénes Ultrasound imaging. Dr. Lőrinczy Dénes Free consultation from the topics of course (discussion of any problem). Dr. Lőrinczy Dénes Free consultation from the topics of course (discussion of any problem). Dr. Lőrinczy Dénes Written test. Dr. Lőrinczy Dénes Written test. Dr. Lőrinczy Dénes Discussion of the test, final evaluation of the course. Dr. Lőrinczy Dénes Discussion of the test, final evaluation of the course. Dr. Lőrinczy Dénes Practices Seminars Exam topics/questions Written test Participants 35 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-KKN THE ENVIRONMENT RELEVANCE AND THE ENVIRONMENTAL MONITORING PUBLIC HEALTH DR. CSABA VARGA, associate professor Department of Public Health Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5– Prerequisites: no prerequisites Topic The main goal of this course is to familiarize the students with the environmental protection as an increasingly important science. Introducing the structure, composition of the most important environmental elements (water, soil, air..), and its threatening processes. Furthermore introducing the global nature protection including its institutional background. The students will be familiar with the environmental protection, and the role of environmental monitoring in public health. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Written test Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department CooSpace - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 The concept, mission and goals of environmental protection. Dr. Varga Csaba The environmental institutions and legislations. Dr. Varga Csaba Background, missions and goals of IUCN. Bérczi Bálint Dániel International environmental agreements. Bérczi Bálint Dániel Conservation biology, conservation medicine. Hungarian national parks and their history. Dr. Varga Csaba Report issues of The Club of Rome. Dr. Varga Csaba The structure of atmosphere. Physical and chemical compounds. Bérczi Bálint Dániel Natural atmospheric processes, which play an important role in the development of air pollution. Bérczi Bálint Dániel The key concepts of air pollution. The distribution of pollutants. Dr. Varga Csaba Air pollution measurements. Dr. Varga Csaba The qualitative and quantitative composition of surface waters. Bérczi Bálint Dániel Monitoring systems of surface waters. The EU water frame directive. Bérczi Bálint Dániel The qualitative and quantitative composition of underground waters. Dr. Varga Csaba 36 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Monitoring systems of underground waters. Dr. Varga Csaba Soil structure, soil types. Bérczi Bálint Dániel The forms of soil pollution and their troubleshooting possibilities. Soil protection. Bérczi Bálint Dániel The definition and types of waste. Selective waste collection. Dr. Varga Csaba Hazardous wastes. Waste management technologies. Dr. Varga Csaba The origin of waste waters, sewage sludges. Bérczi Bálint Dániel Wastewater treatments. Recovery of sewage sludges. Bérczi Bálint Dániel The connection between environmental pollution and climate change. Dr. Varga Csaba Global warming effects on biodiversity. Dr. Varga Csaba The usage possibilities of alternative energy resources (solar energy, biogas, wind energy...). Bérczi Bálint Dániel The risk of alternative energy applications. Bérczi Bálint Dániel Environmental Risk Assessment I Dr. Varga Csaba Environmental Risk Assessment II Dr. Varga Csaba Environmental disasters I Bérczi Bálint Dániel Environmental disasters II Bérczi Bálint Dániel Practices Seminars Exam topics/questions CooSpace Participants 37 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MPR MARKETING IN DIFFERENT LEVELS OF PREVENTION DR. TÍMEA VARJAS, assistant professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 1 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 4 – 30 Prerequisites: no prerequisites Topic What can influence the public attitude to health? How can laymen get information about health and diseases? What are the advantages and disadvantages of media in these topics? How can we use marketing models in disease prevention? These and other important issues can be answered on this course. However the effectiveness of the primary prevention is the highest the most of the resources are assigned to tertiary prevention. The marketing approach is particularly important to medical practitioners, as they are involved in the health sector as an economic system. Students can learn some special marketing method which can help to prevent their patients’ diseases. Conditions for acceptance of the semester Absences should not exceed 15% of lectures and practicals (2x45 min). Otherwise signature of grade book is denied. Examination: written test Mid-term exams Exam: test after the last lecture. Re-take exam in the exam period. Making up for missed classes Based on individual consideration Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Philip Kotler: Marketing Management Lectures 1 2 3 4 5 6 7 8 9 10 11 History of marketing. Development of marketing Dr. Berényi Károly Subliminal message Dr. Berényi Károly „Marketing mix”, „4P” - „7P”. Health as service Dr. Berényi Károly The role of the media - opinion-forming power of news. The role of the media - information abundance Dr. Berényi Károly Promotion in health. Dr. Berényi Károly Seconder prevention and the media. Primary prevention in the media Dr. Berényi Károly Communicable diseases. Non-communicable diseases Dr. Varjas Tímea Epidemiological evidence in primary prevention in non-communicable diseases Dr. Varjas Tímea Lifestyle-marketing Dr. Berényi Károly Nutrition-marketing Dr. Berényi Károly Drug-marketing Dr. Berényi Károly 38 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 Dietary supplement-marketing Dr. Berényi Károly How to use the marketing in health promotion. Primary prevention? Dr. Berényi Károly Pros and cons Health promotion approach to marketing opportunities Dr. Berényi Károly Practices Seminars Exam topics/questions Coospace Participants 39 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MUV PSYCHIATRY AND ART DR. TAMÁS TÉNYI, professor Department of Psychiatry and Psychotherapy Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 1 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 20 Prerequisites: no prerequisites Topic The subject deals with the psychopathology of expression and art therapy. The psychoanalysis of art is introduced and philosophical issues are integrated. Conditions for acceptance of the semester According to the Code of Studies and Examinations Mid-term exams Making up for missed classes According to the Code of Studies and Examinations Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Jakab I : Pictorial Expression in Psychiatry, Akadémia Kiadó, Bp. Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Psychopathology of art I Dr. Tényi Tamás Psychopathology of art II Dr. Tényi Tamás Psychopathology of art III Dr. Tényi Tamás Psychology of creativity I Dr. Tényi Tamás Psychology of creativity II Dr. Tényi Tamás Psychology of creativity III Dr. Tényi Tamás Psychology of creativity IV Dr. Tényi Tamás Poetry of psychotics Dr. Tényi Tamás Van Gogh Dr. Tényi Tamás Art therapy I Dr. Tényi Tamás Art therapy II Dr. Tényi Tamás Music therapy I Dr. Tényi Tamás Music therapy II Dr. Tényi Tamás Summary Dr. Tényi Tamás 40 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions None Participants 41 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-NET INTERNET (COMPUTER APPLICATIONS 2) DR. LÁSZLÓ PÓTÓ, associate professor Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 1 Number of hours/semester: 0 lectures + 14 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 20 Prerequisites: no prerequisites Topic Internet, FTP, E-mail, WWW, chat, VoIP, ... and Facebook, Twitter, ... terms and applications that you can meet everyday. This course guides you in this rapidly growing world. Forming a basic Internet routine. Widen your knowledge and scope of this field. Conditions for acceptance of the semester Active participation on the classes Mid-term exams Tasks to submit, tests to complete at each class Making up for missed classes One extra class Reading material - Obligatory literature - Literature developed by the Department Hand-outs, task lists and tests - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Internet history. Internet access options. continue Connections 1 (email) continue Connections 2 (news-groups, forums, chat, phone, ...) continue Up- and downloading files continue Find and look for information: the web 1. continue Searching information - the web 2. Other Internet services: e-government, e-business, e-learning, etc. continue web2 ... communities, web-based services continue Seminars Exam topics/questions Tasks to submit, tests to complete Participants Dr. Pótó László (POLGABO.PTE) 42 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-SL1 STANFORD LECTURES I: BEHAVIOURAL GENETICS DR. RÓBERT MÁTICS, assistant professor Department of Pathophysiology and Gerontology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 1 – 10 Prerequisites: no prerequisites Topic Prof Robert Sapolsky at Stanford University uploaded a free course on biology of the human behaviour, which has many aspects connected to molecular genetics and behavioral genetics - new fields of research affecting our understanding of sex, aggression, language, diseases like schizophrenia and so on. In this course we will hear and see each one of his 2010 lectures in ca. 45-60 min. pieces and discuss the information delivered. The lectures can be stopped at any point so that emerging questions are negotiated in detail. Curriculum: 1. General introduction 2. Behavioral evolution I. Key facts 3. Behavioral evolution II. Game theory 4. Behavioral evolution III. Misconceptions 5. Behavioral evolution IV. Intersexual conflicts and diseases 6. Molecular genetics I. Chimps to humans 97%, sibling to sibling 50%? 7. Molecular genetics II. Morphology vs function 8. Molecular genetics III. Diseases 9. Molecular genetics IV. Beyond disease 10. Behavioral genetics I. I’ve found the gene for that! 11. Behavioral genetics II. Prenatal effects 12. Behavioral genetics III. Metro dogs 13. Behavioral genetics IV. Gene-environment interaction 14. Summary, questions, discussion, exam Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Written exam at the last session. Making up for missed classes Make-up classes possible, we’ll have to make appointments. Reading material - Obligatory literature - Literature developed by the Department Handouts - Notes Extended notes by Prof Sapolsky, if you need them The lectures can be found at: http://www.youtube.com/watch?v=NNnIGh9g6fA&list=PL848F2368C90DDC3D - Recommended literature Axelrod R, Hamilton WD: The Evolution of Cooperation, Science 211, 1390-1396. Classic paper on the subject, 1981 Cornwallis C et al.: Promiscuity and the Evolutionary Transition to Complex Societies, Nature 466, 969. 2010 Hard, give intro to how to read. Sample of how they think about 43 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 1. General introduction Dr. Mátics Róbert 1. General introduction Dr. Mátics Róbert 2. Behavioral evolution I. Key facts Dr. Mátics Róbert 2. Behavioral evolution I. Key facts, discussion Dr. Mátics Róbert 3. Behavioral evolution II. Game theory Dr. Mátics Róbert 3. Behavioral evolution II. Game theory, discussion Dr. Mátics Róbert 4. Behavioral evolution III. Misconceptions Dr. Mátics Róbert 4. Behavioral evolution III. Misconceptions, discussion Dr. Mátics Róbert 5. Behavioral evolution IV intersexual conflicts and diseases Dr. Mátics Róbert 5. Behavioral evolution IV intersexual conflicts and diseases, discussion Dr. Mátics Róbert 6. Molecular genetics I. Chimps to humans 97%, sibling to sibling 50%? Dr. Mátics Róbert 6. Molecular genetics I. Chimps to humans 97%, sibling to sibling 50%?, discussion Dr. Mátics Róbert 7. Molecular genetics II. Morphology vs function Dr. Mátics Róbert 7. Molecular genetics II. Morphology vs function, discussion Dr. Mátics Róbert 8. Molecular genetics III. Diseases Dr. Mátics Róbert 8. Molecular genetics III. Diseases, discussion Dr. Mátics Róbert 9. Molecular genetics IV. Beyond disease Dr. Mátics Róbert 9. Molecular genetics IV. Beyond disease, discussion Dr. Mátics Róbert 10. Behavioral genetics I. I’ve found the gene for that! Dr. Mátics Róbert 10. Behavioral genetics I. I’ve found the gene for that!, discussion Dr. Mátics Róbert 11. Behavioral genetics II. Prenatal effects Dr. Mátics Róbert 11. Behavioral genetics II. Prenatal effects, discussion Dr. Mátics Róbert 12. Behavioral genetics III. Metro dogs Dr. Mátics Róbert 12. Behavioral genetics III. Metro dogs, discussion Dr. Mátics Róbert 13. Behavioral genetics IV. Gene-environment interaction Dr. Mátics Róbert 13. Behavioral genetics IV. Gene-environment interaction, discussion Dr. Mátics Róbert 14. Summary, questions, discussion Dr. Mátics Róbert Summary, questions, discussion, exam Dr. Mátics Róbert 44 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions No detailed questions are asked about which gene does what, rather a synthesis and deep understanding of the connections between genetics, behaviour, disease etc. should be reached and given back at the exam. Participants Dr. Mátics Róbert (MAREAB.K.JPTE) 45 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-TMR UNIVERSITY LEARNING SKILLS DR. LÁSZLÓ PÓTÓ, associate professor Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 1 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1– Prerequisites: no prerequisites Topic Some students are successful at the university. Some are not, however they were also successful at their earlier schools. What makes this difference? There can be many such reasons. One of the most important is for sure that most students are continuing their earlier learning practice; however the learning circumstances and the requirements were changed a lot. This leads to failure that causes increasing stress. This leads to more failure. The key point is to break this circle: Change your learning habit, develop your learning skills specific to university learning. The aim of this course is to help students in that in order to maximally benefit from their university experience. The result of this course will improve your performance in all other subjects at the university. The new skills and habits will benefit in your private life as well and support your career lifelong. Conditions for acceptance of the semester Maximum 1 absence. Mid-term exams Weekly homeworks Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department Supporting materials supplied by the tutor of the classes. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 Introduction. Changes in learning conditions and requirements. Personality differences. Dr. Pótó László Introduction. Changes in learning conditions and requirements. Personality differences. Dr. Pótó László Lectures and practices. Taking notes. Dr. Pótó László Lectures and practices. Taking notes. Dr. Pótó László Further use of notes. Dr. Pótó László Further use of notes. Dr. Pótó László Reading techniques. Learning from textbooks. Dr. Pótó László Reading techniques. Learning from textbooks. Dr. Pótó László Time management basics for students Dr. Pótó László Time management basics for students Dr. Pótó László Personal and group techniques. Dr. Pótó László Personal and group techniques. Dr. Pótó László Tests and exams. Dr. Pótó László 46 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 14 Tests and exams. Dr. Pótó László Practices Seminars Exam topics/questions Submit all homework (weekly). Participants 47 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-VB1 HOW TO TAKE THE EXAM IN MOLECULAR CELL BIOLOGY? 1 DR. GERGELY BERTA, assistant professor Department of Medical Biology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 1 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 100 Prerequisites: no prerequisites Topic The objective of this course is to imitate the oral exam situation of Molecular Cell Biology (MCB) in a small-group-discussion setting. The list of exam question of MCB will be followed during the course: each time 4-5 students of the 20-25 member class will be examined with one question for each examinee. The examiner is one of the instructors/ professors of the Department who conducts and grades the examination the same way as on „real” exams. All the examiners of the Department will be involved, in a rotation system. The aim of the course is to make students familiar with the stressful atmosphere of oral exams. Only students ready to be exposed to the exam situation week-after-week are invited to take this course. Conditions for acceptance of the semester The grade is determined by continuous performance evaluation. Maximum absences: 4. Mid-term exams Making up for missed classes No possibility to make up for missed classes. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Cooper: The Cell. A Molecular Approach. József Szeberényi-László Komáromy: Molecular Cell Biology Syllabus Lectures Practices Seminars 1-14 Exam trial Exam topics/questions http://www.pote.hu/run/download2.php?idf=253&nyelv=eng Participants Dr. Pap Marianna (PAMFAAO.PTE), Dr. Szeberényi József (SZJGACO.PTE), ifj. Dr. Sétáló György (SEGMAAO.PTE) 48 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-ABI APPLIED BIOMETRICS DR. KORNÉLIA FARKAS-BORBÁS, assistant professor Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 7 lectures + 7 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 15 Prerequisites: no prerequisites Topic Basics of biometrical methods are indispensable to understand the scientific results, to plan own research, and to evaluate data. The main goal of the course is to expand and deepened the basic knowledge of biometrics via solving practical problems. Object of the course is to demonstrate different type of research with most frequently applied biometrical methods, though representative examples or with using of the data of the participants. Conditions for acceptance of the semester Problem solving, oral report Mid-term exams Making up for missed classes Consultation Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Andrew F. Siegel: Statistics and Data Analysis. An introduction, John Wiley & Sons, 1988 Douglas G. Altman: Practical Statistics for Medical Research, Chapman & Hall, 1994 P. Armitage and G. Berry: Statistical Methods in Medical Research, Blackwell Science, 1994 Robert R. Sokal / F. James Rohlf: Biometry, W. H. Freeman and Company, New York, 1981 Lectures 1 2 3 4 5 6 7 General knowledge of researchmethodology Borbásné Dr. Farkas Kornélia Resuscitation of the biostatistical knowledge Borbásné Dr. Farkas Kornélia Varianceanalysis Borbásné Dr. Farkas Kornélia Regressionanalysis Borbásné Dr. Farkas Kornélia Correlationanalysis Borbásné Dr. Farkas Kornélia Survival analysis Borbásné Dr. Farkas Kornélia Factoranalysis Borbásné Dr. Farkas Kornélia Practices 1 2 3 4 5 6 7 Resuscitation of the biostatistical knowledge – using the SPSS Mixed exercise Varianceanalysis, post hoc tests Linear and non-linear regression analysis Parametric and non-parametric(rank-) correlation analysis Survival analysis, survival curves, Logrank-test, Cox-regression analysis... Factoranalysis 49 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Participants Borbásné Dr. Farkas Kornélia (FAKAAA.T.JPTE) 50 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-ANA MEDICAL ENGLISH 2/A - PRESENTATION TECHNIQUES DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ both semesters semester ▪ recommended semester: 2 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 200 Prerequisites: no prerequisites Topic Preparing, understanding and giving biomedical presentations in English. Preparing for presentations in Student Researchers Association in English. Conditions for acceptance of the semester Participation in practicles is obligatory. Absences exceeding 15% but below 25% of the total number of contact hours can be excused by the group tutor. In case absences exceed 25% of the total number of contact hours the course must be regarded as uncompleted. Mid-term exams Making up for missed classes To be discussed with the course tutor in each individual case. Reading material - Obligatory literature - Literature developed by the Department Mark Powel: Presenting in English (How to Give Successful Presentations), 1996 Joan MacLean: Presenting at Medical Meetings, in-house hand-out In-house materials - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 Three planes of biomedical presentations Dr. Rébék-Nagy Gábor Three planes of biomedical presentations Dr. Rébék-Nagy Gábor Textual orientation in BMPs Dr. Rébék-Nagy Gábor Textual orientation in BMPs Dr. Rébék-Nagy Gábor Interpersonal communication in BMPs Dr. Rébék-Nagy Gábor Interpersonal communication in BMPs Dr. Rébék-Nagy Gábor Factual communication patterns in BMPs Dr. Rébék-Nagy Gábor Factual communication patterns in BMPs Dr. Rébék-Nagy Gábor The macrostructure of BMPs and the microstructure of individual sections Dr. Rébék-Nagy Gábor The macrostructure of BMPs and the microstructure of individual sections Dr. Rébék-Nagy Gábor Discourse markers in BMPs Dr. Rébék-Nagy Gábor Discourse markers in BMPs Dr. Rébék-Nagy Gábor Politeness strategies in BMPs Dr. Rébék-Nagy Gábor 51 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Politeness strategies in BMPs Dr. Rébék-Nagy Gábor Evaluation criteria of BMPs Dr. Rébék-Nagy Gábor Evaluation criteria of BMPs Dr. Rébék-Nagy Gábor Physical features of BMPs Dr. Rébék-Nagy Gábor Physical features of BMPs Dr. Rébék-Nagy Gábor Criteria of good practice of BMPs Dr. Rébék-Nagy Gábor Criteria of good practice of BMPs Dr. Rébék-Nagy Gábor Materials collection for BMPs Dr. Rébék-Nagy Gábor Materials collection for BMPs Dr. Rébék-Nagy Gábor Power point presentation tips Dr. Rébék-Nagy Gábor Power point presentation tips Dr. Rébék-Nagy Gábor Presentation by students Dr. Rébék-Nagy Gábor Presentation by students Dr. Rébék-Nagy Gábor Presentation by students Dr. Rébék-Nagy Gábor Course evaluation Dr. Rébék-Nagy Gábor Practices Seminars Exam topics/questions 1/ A 10-minute presentation in English on a biomedical subject 2/ An essay of 900-1000 words on the theory of giving presentations Participants Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE) 52 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-ANB MEDICAL ENGLISH 2/B - TAKING MEDICAL CASE HISTORIES IN ENGLISH DR. VILMOS WARTA, assistant professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ both semesters semester ▪ recommended semester: 2 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 20 Prerequisites: no prerequisites Topic The course intends to prepare the participants for effective communication with English-speaking patients. Conditions for acceptance of the semester Participation in lectures is obligatory. Absences exceeding 15% but below 25% of the total number of contact hours can be excused by the group tutor. In case absences exceed 25% of the total number of contact hours the course must be regarded as uncompleted. Mid-term exams Making up for missed classes To be discussed with the course tutor in each individual case. Reading material - Obligatory literature - Literature developed by the Department Lecture slides - Notes M. Györffy: English for Doctors (Authentic Consulting Room Activities for Doctors, Dentists, Students and Nurses), Idióma Bt., Pécs, 2001 - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction Dr. Warta Vilmos Introduction Dr. Warta Vilmos Politeness strategies Dr. Warta Vilmos Politeness strategies Dr. Warta Vilmos Internal medicine (1) Dr. Warta Vilmos Internal medicine (1) Dr. Warta Vilmos Internal medicine (2) Dr. Warta Vilmos Internal medicine (2) Dr. Warta Vilmos Obstetrics and gynaecology Dr. Warta Vilmos Obstetrics and gynaecology Dr. Warta Vilmos Surgery Dr. Warta Vilmos Surgery Dr. Warta Vilmos Urology Dr. Warta Vilmos Urology Dr. Warta Vilmos 53 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Paediatrics Dr. Warta Vilmos Paediatrics Dr. Warta Vilmos Face Threatening Activities (1) Dr. Warta Vilmos Face Threatening Activities (1) Dr. Warta Vilmos Face Threatening Activities (2) Dr. Warta Vilmos Face Threatening Activities (2) Dr. Warta Vilmos General Practitioners Dr. Warta Vilmos General Practitioners Dr. Warta Vilmos Written test Dr. Warta Vilmos Written test Dr. Warta Vilmos Consolidation Dr. Warta Vilmos Consolidation Dr. Warta Vilmos Course evaluation Dr. Warta Vilmos Course evaluation Dr. Warta Vilmos Practices Seminars Exam topics/questions 1) one written test 2) one essay Participants 54 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-BO2 BIOPHYSICS SEMINARS 2 DR. ANDRÁS SZILÁRD LUKÁCS, assistant professor Department of Biophysics Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 40 Prerequisites: OAA-BI2 parallel Topic The objective of the course is to advance the acquisition of knowledge and skills related to Biophysics 2. Object-oriented discussions and problem solving sessions are organized in interactive small-group seminars. Conditions for acceptance of the semester Maximum of three absences. Mid-term exams The grade of this subject is equal to the result of the mid-term test. In the case of failure the test can be retaken during the first week of the exam period. Making up for missed classes None. After previous agreement with the lecturer the student can attend the seminar with another group another day, the same week. Reading material - Obligatory literature - Literature developed by the Department Online materials on departmental website (http://biofizika.aok.pte.hu) - Notes Damjanovich Sándor, Fidy Judit, Szöllősi János (eds.): Medical Biophysics, Medicina, Budapest, 2008 - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Radioactivity. Radioactive radiations Spectrophotometry Infrared and Raman spectroscopy Fluorescence spectroscopy Fluorescence anisotropy. FRET Light microscopy, fluorescence microscopy Modern microscopic methods. FRAP Flow cytometry. NMR MRI X-ray diagnostics. CT Gamma-camera, SPECT, PET Ultrasound Test writing Exam topics/questions Can be found on the departmental website (http://biofizika.aok.pte.hu) Participants Dr. Kengyel András Miklós (KEAFACO.PTE), Dr. Lukács András Szilárd (LUATAA0.PTE), Futó Kinga (FUKIAAT.PTE), Huber Tamás (HUTEAB.T.JPTE), Kilián Balázsné Raics Katalin (RAKHAAT.PTE), Kollár Veronika Tünde (KOVGACT.PTE) 55 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-BVK CHEMISTRY OF BIOACTIVE ORGANIC COMPOUNDS DR. TAMÁS LÓRÁND, associate professor Department of Biochemistry and Medical Chemistry Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 50 Prerequisites: OAA-OM1 completed Topic The course discusses the chemical and biological properties of the vitamins, some alkaloids and the more important antibiotics. In the case of antibiotics as a major goal, the program affords a short overview of the structure of these compounds, biological effect, relationships and the biochemical mechanism of action. It gives a basic knowledge and helps in the understanding of the later subjects such as biochemistry, microbiology, as well as pharmacology. Conditions for acceptance of the semester Successful written examination. Mid-term exams It is published at the beginning of the semester. Making up for missed classes None. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature P. Gergely (ed.): Organic and Bioorganic Chemistry for Medical Students, Univ. Med. School of Debrecen, latest edition Lubert Stryer: Biochemistry, W.H. Freeman and Co., latest edition Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Water soluble vitamins I Dr. Agócs Attila Water soluble vitamins II. Dr. Agócs Attila Fat soluble vitamins I Dr. Agócs Attila Fat soluble vitamins II Dr. Agócs Attila Pigments of porphyirin skeleton I Dr. Agócs Attila Pigments of porphyirin skeleton II. Dr. Agócs Attila Pigments of flavonoid and anthocynidin skeleton I Dr. Agócs Attila Pigments of flavonoid and anthocynidin skeleton II Dr. Agócs Attila Carotenoids I Dr. Agócs Attila Carotenoids II Dr. Agócs Attila Introduction to the antibiotics I Dr. Lóránd Tamás Introduction to the antibiotics II Dr. Lóránd Tamás 56 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Beta-lactam antibiotics, penicillins Dr. Lóránd Tamás Beta- lactam antibiotics, cephalosporins I Dr. Lóránd Tamás Beta- lactam antibiotics, cephalosporins II Dr. Lóránd Tamás Beta- lactam antibiotics, other beta-lactams I Dr. Lóránd Tamás Beta- lactam antibiotics, other beta-lactams II Dr. Lóránd Tamás Aminoglycosides I Dr. Lóránd Tamás Aminoglycosides II Dr. Lóránd Tamás Macrolides I Dr. Lóránd Tamás Macrolides II Dr. Lóránd Tamás Tetracyclines I Dr. Lóránd Tamás Tetracyclines II Dr. Lóránd Tamás Glycopeptides I Dr. Lóránd Tamás Other antibiotics Dr. Lóránd Tamás Antifungal antibiotics Dr. Lóránd Tamás Alkaloids of medical importance Dr. Lóránd Tamás Test Paper. Dr. Lóránd Tamás Practices Seminars Exam topics/questions http://aok.pte.hu/index.php?page=egyseg&egy_id=20&nyelv=eng&menu=okt_anyag Participants 57 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-ELH OBESITY - THE „EPIDEMIC” OF THE MODERN AGE DR. DÉNES MOLNÁR, professor Department of Paediatrics Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 20 Prerequisites: no prerequisites Topic The general aim of the course is to emphasise the importance of (primary) prevention within medicine and to develop preventive approach in students. Obesity, childhood obesity is a problem, which became a common disease by nowadays, and it is one of the main risk factors of the leading cardiovascular and cancerous deaths. The review of the significance and deficiency of health promotion and the phenomenon and consequences of globalisation. Those who accomplish the course will have the opportunity to give presentations in this topic in primary and secondary schools, thus making use of their knowledge gained, and as future doctors participating in the development of the health care system. For the accomplishment of the course and for the presentations HuMSIRC points are given, which are counted at the application to summer exchange practice organised by HuMSIRC. Conditions for acceptance of the semester By the Code of the Studies and Examinations. Participation in seminars, passing a multiple choice test with at least 70%. 2 absences are permitted. Mid-term exams Making up for missed classes according to personal discussion. Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature http://ebook.ecog-obesity.eu Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction, course outline, aims of the course. The significance of obesity. References to Public Health (Dr. Dénes Molnár, professor) Introduction, course outline, aims of the course. The significance of obesity. References to Public Health (Dr. Dénes Molnár, professor) Physiological and pathophysiological background: Factors influencing the regulation of body weight. (Dr. Zoltán Szelényi, professor) Physiological and pathophysiological background: Factors influencing the regulation of body weight. (Dr. Zoltán Szelényi, professor) Psychological aspects of nutritional disorders. (Dr. János Kállai) Psychological aspects of nutritional disorders. (Dr. János Kállai) The effects of globalisation on lifestyle and health. Health promotion. (Dr. Éva Kovács) The effects of globalisation on lifestyle and health. Health promotion. (Dr. Éva Kovács) Types and the importance of prevention, methods of prevention. Types and the importance of prevention, methods of prevention. Visit of a dietitian, nutritionist. Role of physical activity, inactivity. Visit of a dietitian, nutritionist. Role of physical activity, inactivity. Writing the test. Writing the test. Exam topics/questions Participants Dr. Erhardt Éva (EREMAAO.PTE), Dr. Molnár Dénes (MODHAAE.PTE) 58 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-EMA BASIC PRINCIPLES OF ELECTRON MICROSCOPY IN CLINICAL PRACTICE AND BIOLOGICAL RESEARCH DR. HAJNALKA GABRIELLA ÁBRAHÁM, associate professor Central Electron Microscope Laboratory Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 24 lectures + 4 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 40 Prerequisites: OAA-MB1 completed Topic Methods of electron microscopic fixation, embedding and sectioning and the use of the electron microscope. Demonstration of the subcellular elements in details and of a few tissues and organs. Demonstration of the electron microscopic methods used in the biological research. The use of electron microscopic methods in the clinical practice. The basic principles of electron microscopy will be discussed and we provide information about the mode and the use of electron microscopy in the basic research and in the clinical practice. Conditions for acceptance of the semester Participation on 80% of the classes. Oral examination with analysis of electron microscopic photographs Mid-term exams Making up for missed classes No possibility Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Suggested only: Dr. Szabolcs Virágh: Ultrastructural Pathology and Diagnostic Electron Microscopy Leon Weiss: Histology. Cell and Tissue Biology Lectures 1 2 3 4 5 6 7 8 9 10 11 Purpose and indication of the electron microscopic examination. The role of fixation in tissue preservation, the recognition of cells, cellular organelles etc. Dr. Seress László Antal Most frequent failures in the electronmicroscopic practice Dr. Seress László Antal Optimal fixation for electron microscopy. Composition of fixatives for different tissue samples. Electron microscopy of formaldehyde fixed and paraffin embedded materials. Dr. Seress László Antal Samples taken by autopsy or biopsy. Perfusion of experimental animals for electron microscopy. Dr. Seress László Antal The ultrastructure of the cell I Dr. Seress László Antal The ultrastructure of the cell II Dr. Seress László Antal The ultrastructure of the cell III Dr. Seress László Antal The ultrastructure of the cell IV Dr. Seress László Antal The ultrastructure of the cell V Dr. Ábrahám Hajnalka Gabriella The ultrastructure of the cells VI Dr. Ábrahám Hajnalka Gabriella Ultrastructures of neurons (axon, dendrite, synapses) Dr. Seress László Antal 59 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 15 16 17 18 19 20 21 22 23 24 Ultrastructure of glial cells Dr. Seress László Antal The ultrastructure of kidney Dr. Ábrahám Hajnalka Gabriella The ultrastructure of the liver Dr. Ábrahám Hajnalka Gabriella Ultrastructure of the muscle. Dr. Ábrahám Hajnalka Gabriella Necrotic and apoptotic changes in the dying cells. Dark cells. Dr. Ábrahám Hajnalka Gabriella Combined light and electron microscopic methods, such as Golgi/EM, Timm/EM, immunocytochemistry/EM. Dr. Seress László Antal Combination of degeneration and axon transport methods with electron microscopy. Dr. Seress László Antal Ultrastructure of bacteria and viruses. Dr. Ábrahám Hajnalka Gabriella Cytosceleton Dr. Seress László Antal Intercellular connections Dr. Seress László Antal The use of EM in the biological research I Dr. Seress László Antal The use of EM in biological research II Dr. Seress László Antal Examination Dr. Seress László Antal Practices 1 2 3 4 Electron microscopic grids and coating membranes. The use of transmission electron microscope (light, focus, contrast, photo). Analysis of tissue in the electron microscope, virus, bacteria Analysis of tissue in the electron microscope, liver, muscle. Analysis of tissue in the electron microscope, neurons, glial cells. Seminars Exam topics/questions None Participants Dr. Ábrahám Hajnalka Gabriella (ABHMAAO.PTE), Dr. Seress László Antal (SELMAAO.PTE) 60 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-H2A MEDICAL HUNGARIAN 2A - COMMUNICATION SKILLS DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 2 – 25 Prerequisites: OAE-H2B parallel + OAE-H1A completed Topic This course is meant to serve as a transition between general and specific (doctor-patient) communication skills development. Conditions for acceptance of the semester Participation in class work is obligatory. In case absences exceed 25% of total class time, the course will be regarded as uncompleted. In the case of absences up to 25% of total class time, oral examination will have to be taken Mid-term exams Making up for missed classes In the case of absences up to 25% of total class time, oral examination will have to be taken. Reading material - Obligatory literature - Literature developed by the Department http://aok.pte.hu/index.php?page=egyseg&egy_id=60&nyelv=eng&menu=okt_anyag - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Logical relations, comparison Logical relations, comparison Giving orientation, informing people Giving orientation, informing people Giving descriptions, requesting and providing information Giving descriptions, requesting and providing information Cause and consequence Cause and consequence Narratives Narratives Giving advice Giving advice Expressing uncertainty Expressing uncertainty Test 1 Test 1 Descriptions, warning Descriptions, warning Polite request, command and warning Polite request, command and warning Parts of the human body, pain, basic symptoms Parts of the human body, pain, basic symptoms History taking: presenting complaints, location, direction and character of pain History taking: presenting complaints, location, direction and character of pain Simple examinations, diagnostic procedures Simple examinations, diagnostic procedures Test 2 Course evaluation 61 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Participants Dr. Hegedűs Anita (HEAAAA.B.JPTE), Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE), Dr. Warta Vilmos (WAVEAB.B.JPTE), Eklicsné Dr. Lepenye Katalin (EKLAXA.B.JPTE), Hamarné Sávay Judit (HASMAAO.PTE), Hild Gabriella (MAGAAD.B.JPTE), Horváth Lilla Anita (HOLFABP..PTE), Kurdiné Molnár Eszter (KUMPAAK.PTE), Lokodiné Szolcsányi Judit (LOSIAAB.PTE), Mészégetőné Halmos Éva (MEHHABE.PTE), Nagy Gabriella (NAGMAAO.PTE), Ronczykné Berta Anikó (BEAAAI.B.JPTE), Szántóné Csongor Alexandra (CSAAAA.B.JPTE), Váradi Katalin (VAKHAAE.PTE) 62 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-H2B MEDICAL HUNGARIAN 2B - LANGUAGE POINTS DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OAE-H2A parallel + OAE-H1B completed Topic This course is meant to provide the language basis for advanced communication between doctors and patients. Conditions for acceptance of the semester Participation in class work is obligatory. In case absences exceed 25% of total class time, the course will be regarded as uncompleted. In the case of absences up to 25% of total class time, oral examination will have to be taken Mid-term exams Making up for missed classes Participation is obligatory. Reading material - Obligatory literature - Literature developed by the Department http://aok.pte.hu/index.php?page=egyseg&egy_id=60&nyelv=eng&menu=okt_anyag - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Expressing possessing, genitive case Expressing possessing, genitive case Adjectives and nouns: eg. nátha-náthás, nominalization: eg köhög-köhögés Adjectives and nouns: eg. nátha-náthás, nominalization: eg köhög-köhögés Question words, concerning time and location and adverbs of time Question words, concerning time and location and adverbs of time Expressing cause, giving explanation Expressing cause, giving explanation Functions of past tense in medical Hungarian Functions of past tense in medical Hungarian Future tense, modality expressing ability and volition Future tense, modality expressing ability and volition Impersonalization Impersonalization Consolidation test 1 Test 1 Modality expressing necessity, possibility and prohibition Modality expressing necessity, possibility and prohibition Definite and indefinite conjugation, prefixed verbs Definite and indefinite conjugation, prefixed verbs Imperative forms Imperative forms Giving instructions to patients Giving instructions to patients Giving instructions to patients Consolidation Test1 Course evaluation 63 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Participants Dr. Hegedűs Anita (HEAAAA.B.JPTE), Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE), Dr. Warta Vilmos (WAVEAB.B.JPTE), Eklicsné Dr. Lepenye Katalin (EKLAXA.B.JPTE), Hamarné Sávay Judit (HASMAAO.PTE), Hild Gabriella (MAGAAD.B.JPTE), Horváth Lilla Anita (HOLFABP..PTE), Kurdiné Molnár Eszter (KUMPAAK.PTE), Lokodiné Szolcsányi Judit (LOSIAAB.PTE), Mészégetőné Halmos Éva (MEHHABE.PTE), Nagy Gabriella (NAGMAAO.PTE), Ronczykné Berta Anikó (BEAAAI.B.JPTE), Szántóné Csongor Alexandra (CSAAAA.B.JPTE), Váradi Katalin (VAKHAAE.PTE) 64 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-MOM MOLECULAR MEDICINE DR. JÓZSEF SZEBERÉNYI, professor Department of Medical Biology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5– Prerequisites: no prerequisites Topic Short description of the course: The course covers overlapping fields of molecular cell biology and clinical genetics, discusses the significance of molecular genetics in clinical medicine. Main topics: the relationship between genotype and phenotype; human genome and phenome program; mosaicism; microsatellite instability; genomic imprinting; embryo cloning; gene therapy; ethical aspects of molecular medicine. The main educational task of the subject: The aim of the course is to develop connections between basic science and clinical medicine; to convince students that knowledge of molecular biology is essential to understand the pathomechanism of diseases; to give students the chance to face clinical problems even at the beginning of their medical studies. Conditions for acceptance of the semester According to the Code of Studies Mid-term exams The course ends with a test of multiple-choice questions. The students have a chance to improve their grade on an oral exam. Making up for missed classes None. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Gelehrter-Collins: Principles of Medical Genetics Cooper-Mausman: The Cell. A Molecular Approach Lectures 1 2 3 4 5 6 7 8 9 10 11 DNA fingerprinting Dr. Szeberényi József DNA fingerprinting Dr. Szeberényi József Genotype-phenotype; phenotype-genotype Dr. Kosztolányi György Genotype-phenotype; phenotype-genotype Dr. Kosztolányi György Mosaicism Dr. Kosztolányi György Mosaicism Dr. Kosztolányi György Human genome project Dr. Szeberényi József Human genome project Dr. Szeberényi József The RNA world Dr. Szeberényi József The RNA world Dr. Szeberényi József Non-Mendelian monogenic inheritance Dr. Kosztolányi György 65 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Non-Mendelian monogenic inheritance Dr. Kosztolányi György National holiday Dr. Szeberényi József National holiday Dr. Szeberényi József Diseases of protein folding Dr. Szeberényi József Diseases of protein folding Dr. Szeberényi József Genetics and environment: epigenetics Dr. Kosztolányi György Genetics and environment: epigenetics Dr. Kosztolányi György Intracellular antibodies Dr. Szeberényi József Intracellular antibodies Dr. Szeberényi József Molecular cytogenetics Dr. Szeberényi József Molecular cytogenetics Dr. Szeberényi József Cloning of mammals Dr. Szeberényi József Cloning of mammals Dr. Szeberényi József Ethical aspects of molecular genetics Dr. Kosztolányi György Ethical aspects of molecular genetics Dr. Kosztolányi György Closing test Dr. Szeberényi József Closing test Dr. Szeberényi József Practices Seminars Exam topics/questions Participants 66 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-MS2 EXPERIMENTS IN MOLECULAR CELL BIOLOGY 2 DR. JÓZSEF SZEBERÉNYI, professor Department of Medical Biology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 14 lectures + 0 practices + 14 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 40 Prerequisites: OAE-MS1 completed Topic The main objectives of this course are to stimulate interest in students toward the experimental approach to cell biology, to develop their interpretation, problem-solving skills and their creative way of thinking. This course is an advanced course tightly connected to the compulsory subject Molecular Cell Biology. The lectures cover the important discoveries of cell and molecular biology, using an experimental approach. On the small-group-discussions phenomena of molecular cell biology are described and discussed using problembased learning techniques (e.g. figure analysis, planning of experiments, application tests) developed in the Department of Medical Biology. The compulsory subject deals with these same topics with more conventional educational methods. Although the course helps to understand principles and processes in cell biology, it is in no way required to successfully complete the compulsory subject. Conditions for acceptance of the semester According to the Code of Studies. Mid-term exams Making up for missed classes None. Reading material - Obligatory literature - Literature developed by the Department Educational materials on the homepage of the Department of Medical Biology: Problem-solving tests in molecular cell biology Figure analysis in molecular cell biology - Notes - Recommended literature Cooper-Hausman: The Cell. A Molecular Approach Szeberényi J.: Experiments in Molecular Cell Biology Lectures 1 2 3 4 5 6 7 8 9 10 Methods to study the cytoskeleton Dr. Szeberényi József Methods to study the cell membrane and the extracellular matrix Dr. Szeberényi József Methods to study receptor proteins Dr. Szeberényi József Methods to study G protein-mediated signaling processes Dr. Szeberényi József Methods to study growth factor and cytokine signaling Dr. Szeberényi József Methods to study apoptosis Dr. Szeberényi József Test Dr. Szeberényi József Methods to study oncogenic viruses Dr. Szeberényi József Methods to study cellular oncogenes Dr. Szeberényi József Methods to study tumor suppressor genes Dr. Szeberényi József 67 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 Methods to study abnormalities in the cell cycle Dr. Szeberényi József Methods of human genetics Dr. Szeberényi József Methods of molecular medicine Dr. Szeberényi József Final test Dr. Szeberényi József Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Examples for the analysis of the cytoskeleton Examples for the analysis of the cell membrane Examples for the analysis of receptors Examples for the analysis of the role of cAMP and lipid-derived second messengers Examples for the analysis of the role of tyrosine kinases Examples for the analysis of apoptosis Test Examples for the analysis of oncogenic viruses Examples for the analysis of cellular oncogenes Examples for the analysis of tumor suppressor genes Examples for the analysis of abnormal cell cycle Examples for the methods of cytogenetics Examples for the methods of molecular diagnostics Final test Exam topics/questions Multiple-choice test. Participants Dr. Bátor Judit (BAJFAAO.PTE), Dr. Berta Gergely (BEGFADO.PTE), Dr. Kemény Ágnes (KEAAAA.T.JPTE), Dr. Pap Marianna (PAMFAAO.PTE), Harci Alexandra (HAAGABT.PTE), ifj. Dr. Sétáló György (SEGMAAO.PTE), Németh Mária (NEMGAAT.PTE), Schipp Renáta (SCRDAA.T.JPTE), Varga Judit (VAJGACT.PTE) 68 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-TAR NUTRITION AND CANCER DR. ISTVÁN KISS, professor Department of Public Health Medicine Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 26 lectures + 2 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: no prerequisites Topic Nutrition takes an important part in the formation of several types of cancer. Approximately 35% of human cancers is attributed to nutrition factors. The importance of these factors and the way of their action is discussed during the course. After the theoretical introduction the human epidemiological results are interpreted and practical pieces of advice are given for healthy and carcinopreventive diet. The primary prevention is the most effective method to prevent cancers. The possible cancer preventive methods in nutrition will be demonstrated for the students during the lectures. Conditions for acceptance of the semester Participation in lectures is obligatory which is registered. Absences should not exceed 15% of lectures (4x45 min). Otherwise signature of grade book is denied. Mid-term exams Written exam. Making up for missed classes There are no make-up classes. Reading material - Obligatory literature - Literature developed by the Department Educational material uploaded on CooSpace. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 The multistep model of carcinogenesis. Dr. Kiss István Possibilities for cancer prevention. Dr. Kiss István The role of energy intake in carcinogenesis. Dr. Kiss István The role of protein, carbohydrate intake in carcinogenesis. Dr. Kiss István The role of fat intake in carcinogenesis I. Dr. Kiss István The role of fat intake in carcinogenesis II. Dr. Kiss István The role of alcohol in carcinogenesis I. Bérczi Bálint Dániel The role of alcohol in carcinogenesis II. Bérczi Bálint Dániel Compounds of plant origin and their role in carcinogenesis I. Dr. Kiss István Compounds of plant origin and their role in carcinogenesis II. Dr. Kiss István Compounds of plant origin and their role in carcinogenesis III. Dr. Rákosy Zsuzsa Compounds of plant origin and their role in carcinogenesis IV. Dr. Rákosy Zsuzsa 69 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 15 16 17 18 19 20 21 22 23 24 25 26 The role of micro-nutrients in cancer formation. Dr. Gyöngyi Zoltán Drinking water and cancers. Dr. Gyöngyi Zoltán Genetically modified foods I. Dr. Gyöngyi Zoltán Genetically modified foods II. Dr. Gyöngyi Zoltán Nutrigenomics. Dr. Gombos Katalin Epigenetics and cancer. Dr. Gombos Katalin Anticarcinogenic compounds in foods I. Dr. Rákosy Zsuzsa Anticarcinogenic compounds in foods II. Dr. Rákosy Zsuzsa Food pollutants and food additives I. Vági Zsolt József Food pollutants and food additives II. Vági Zsolt József The role of kitchen technology in the formation of cancers I. Vági Zsolt József The role of kitchen technology in the formation of cancers II. Vági Zsolt József The relationship between nutrition and cancers I. Dr. Gyöngyi Zoltán The relationship between nutrition and cancers II. Dr. Gyöngyi Zoltán Practices 1 2 Dietary recommendations I. Dietary recommendations II. Seminars Exam topics/questions Questions for the retake-exam: 1. Epidemiology of cancers 2. Multistep model of carcinogenesis 3. The role of energy intake in the formation of cancers 4. The relationship between fat intake and carcinogenesis 5. The relationship between protein and carbohydrate intake and carcinogenesis 6. The relationship between alcohol consumption and carcinogenesis 7. Vitamins, trace elements and carcinogenesis 8. Food additives and cancer formation 9. Phytochemicals’ role in cancer formation and cancer prevention 10. Anticarcinogenic compounds 11. Nutrition and colorectal carcinoma 12. Nutrition and gastric cancer 13. Nutrition and lung cancer 14. Nutrition and oral cavity cancer 15. Nutrition and breast cancer Participants Dr. Kiss István (KIIFAD.A.JPTE) 70 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-TBG DISSECTION PRACTICES IN REGIONAL ANATOMY DR. TIBOR HOLLÓSY, assistant professor Department of Anatomy Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 1 lectures + 27 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 160 Prerequisites: OAA-AA1 parallel Topic The course offers extra dissecting room practices in regional anatomy with the assistance of experienced teachers. To achieve advanced skill in sectioning human body, and to get a deeper understanding of it. Conditions for acceptance of the semester Two regions should be dissected by each student under supervision of teachers. The semester score (1 to 5) will be based on the quality of the dissection. To receive the credit, at least score 2 (satisfactory) should be received and the student must participate in more than 80% of the practices. Mid-term exams Making up for missed classes Individual study on the consecutive practices of the group. Reading material - Obligatory literature - Literature developed by the Department http://an-server.pote.hu/ - Notes - Recommended literature Lectures 1 General practical instructions. Dr. Hollósy Tibor Practices 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Dissection of the ventral regions of extremities. Evaluation of the prepared regions. Evaluation of the prepared regions. Dissection of the dorsal regions of extremities, nuchal region and muscles of the back. Dissection of the dorsal regions of extremities, nuchal region and muscles of the back. Dissection of the dorsal regions of extremities, nuchal region and muscles of the back. Dissection of the dorsal regions of extremities, nuchal region and muscles of the back. Dissection of the dorsal regions of extremities, nuchal region and muscles of the back. Dissection of the dorsal regions of extremities, nuchal region and muscles of the back. Dissection of the dorsal regions of extremities, nuchal region and muscles of the back. Dissection of the dorsal regions of extremities, nuchal region and muscles of the back. Dissection of the dorsal regions of extremities, nuchal region and muscles of the back. 71 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 27 28 Evaluation of the prepared regions. Evaluation of the prepared regions. Seminars Exam topics/questions http://an-server.pote.hu Participants Dr. Czeiter Endre (CZEFAAO.PTE), Dr. Farkas József (FAJHAAO.PTE), Dr. Fülöp Balázs Dániel (FUBOAA-O.PTE), Dr. Hollósy Tibor (HOTFAAO.PTE), Dr. Horváth Gábor (HOGNAAO.PTE), Fábián Eszter (FAEGAAT.PTE), Kovács László Ákos (KOLQAAO.PTE), Opper Balázs (OPBFAB.T.JPTE) 72 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-ATS HEALTH EFFECTS OF ALTERNATIVE DIETARY HABITS DR. TÍMEA VARJAS, assistant professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 4 – 30 Prerequisites: no prerequisites Topic The aim of the course is to widen the knowledge of the medical, pharmacy and dental students about the effects of alternative diet forms on health status. This will include an assessment by a professional certified nutritionist. Outlining the advantages and disadvantages of the diets (on both health and financial levels) are also part of the course. Conditions for acceptance of the semester Absences should not exceed 15% of lectures and practicals (2x45 min). Otherwise signature of grade book is denied. Examination: written test Mid-term exams Exam: test after the last lecture. Re-take exam in the exam period. Making up for missed classes Based on individual consideration Reading material - Obligatory literature - Literature developed by the Department PPT-presentations (Coospace) - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 The vegetarian diet I. Lacto, ovo, lacto-ovo vegetarian nutrition Szíjártó György Ágoston The vegetarian diet II. Strict vegan, pesco, pollo vegetarian nutrition Szíjártó György Ágoston Vegan diet I. Fruitarianism, raw food diet Szíjártó György Ágoston Vegan diet II. Macrobiotic diet Szíjártó György Ágoston The reform diet Szíjártó György Ágoston Separation diets I. Diamond’s fit-for-life diet Szíjártó György Ágoston Separation diets II. Hay’s alkalizing, acidifying diet Szíjártó György Ágoston Fashion diets I. Bruker’s diet Szíjártó György Ágoston Fashion diets II. Steine’s diet Szíjártó György Ágoston Atkins diet Szíjártó György Ágoston The Paleolithic diet Szíjártó György Ágoston Norbi-Update diet Szíjártó György Ágoston 73 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Mediterranean diet Szíjártó György Ágoston Importance of organic foods in the diet Dr. Varjas Tímea Practices Seminars Exam topics/questions Coospace Participants 74 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-BET HEALTH SCIENCE OF WINE DR. ISTVÁN KISS, professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 2 Number of hours/semester: 12 lectures + 2 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: no prerequisites Topic Ensuring healthy drinking water was always an important question in the history of mankind. This typically mean the fight against waterborn infectious diseases. Concerning these efforts people found the secret of wine making. During the Middle Ages Hungary became a wine consuming and wine producing country. After the World War II the wine consuming habits took a wrong direction, with an increase in the consumption of spirits and beer. However, recently hundreds of publications demonstrated the beneficial effects of moderate wine consumption, in the prevention of several diseases, e.g. cardiovascular diseases and cancer. The probable major cause of the so called French paradox, is also the consumption of red wine. This course tries to give a summary from the viewpoint of public health, physiology, toxicology, epidemiology and nutrition. The students will be familiar with the health risks and benefits of wine consumption, they will be able to critically evaluate nutrition (and drinking) related facts and data. Conditions for acceptance of the semester Participation in lectures is obligatory which is registered. Absences should not exceed 15% of lectures (2x45 min). Otherwise signature of grade book is denied. Mid-term exams Written test Making up for missed classes There are no make-up classes. Reading material - Obligatory literature - Literature developed by the Department Educational material uploaded on CooSpace. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 Epidemiological data on the association between health status and wine consumption I Bérczi Bálint Dániel Epidemiological data on the association between health status and wine consumption II Bérczi Bálint Dániel Health risks associated with alcohol consumption I Bérczi Bálint Dániel Health risks associated with alcohol consumption II Bérczi Bálint Dániel Health risks associated with alcohol consumption III Bérczi Bálint Dániel Health risks associated with alcohol consumption IV Bérczi Bálint Dániel Preventive substances in wine I Dr. Kiss István Preventive substances in wine II Dr. Kiss István Role of wine in the prevention of diseases I Dr. Kiss István Role of wine in the prevention of diseases II Dr. Kiss István 75 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 Wine culture in Hungary and in Europe I Bérczi Bálint Dániel Wine culture in Hungary and in Europe II Bérczi Bálint Dániel Practices 13 14 Wine production, consumption and culture I Wine production, consumption and culture II Seminars Exam topics/questions CooSpace Participants Dr. Kiss István (KIIFAD.A.JPTE) 76 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-CIR THE CYTOSKELETAL SYSTEM DR. BEÁTA BUGYI, assistant professor Department of Biophysics Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 20 Prerequisites: no prerequisites Topic The cytoskeletal system is composed of different proteins networks. The cytoskeleton has versatile structural and functional features, which are essential for almost all cellular processes. The dysfunctioning of the cytoskeleton can often results in pathological alterations of cellular functions, which can lead to diseases. In the first module the course we discuss the components and properties of the cytoskeletal protein networks. The second module lays special emphasis on presenting the pathological alterations of the cytoskeletal system and the underlying diseases. I. module: Components and functions of the cytoskeleton. II. module: Pathological alterations and diseases related to the cytoskeleton. III. module: Biophysical approaches in the investigation of the cytoskeleton. Conditions for acceptance of the semester A maximum of three absences, and a passed test or presentation at the end of the semester. Mid-term exams Making up for missed classes None. Reading material - Obligatory literature - Literature developed by the Department http://biofizika.aok.pte.hu - Notes - Recommended literature Jonathon Howard: Mechanics of Motor Proteins and the Cytoskeleton, 2005 S. Trachtenberg: The Prokaryotic Cytoskeleton: A Written Symposium, Journal of Molecular Microbiology and Biotechnology, 2006 Leslie P. Gartner, James L. Hiatt (eds.): Color Textbook of Histology 3, illustrated, revised, Saunders/Elsevier, 2007 Online materials on departmental website (http://biofizika.aok.pte.hu) Lectures 1 2 3 4 5 6 7 8 9 10 Introduction Dr. Bugyi Beáta Cytoskeletal filaments: actin, microtubule, intermediate filament cytoskeleton. Dr. Bugyi Beáta Cytoskeletal filament associated proteins and their activities. Dr. Bugyi Beáta Functions of the cytoskeleton 1. Dr. Bugyi Beáta Functions of the cytoskeleton 2. Dr. Bugyi Beáta Actin-associated diseases 1. Muscle myopathies. Dr. Kengyel András Miklós Actin-associated diseases 2. Viruses, pathogens. Dr. Kengyel András Miklós Actin-associated diseases 3. Dr. Kengyel András Miklós Microtubule-associated diseases. Dr. Bugyi Beáta Intermediate filament-associated diseases. Dr. Bugyi Beáta 77 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 Therapeutic approaches targeting the cytoskeleton. Dr. Bugyi Beáta Biophysical approaches to study the cytoskeleton 1. Dr. Bugyi Beáta Biophysical approaches to study the cytoskeleton 2. Dr. Bugyi Beáta Test Dr. Bugyi Beáta Practices Seminars Exam topics/questions Can be found on the departmental website (http://biofizika.aok.pte.hu). Participants 78 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EGN EPIGENETICS - NON-GENETIC INHERITANCE AND ITS MEDICAL ASPECTS DR. ISTVÁN KISS, professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 12 lectures + 0 practices + 2 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: no prerequisites Topic Contribution of environmentally induced molecular signals to disease development is an interesting and actual question of molecular epidemiology. Epigenetics can significantly contribute to this area by studying the effect of environmental factors on gene regulation causing phenotypically inherited changes. It can present a novel approach in the characterization of the connection between exposure, genes and disease development. The course tries to familiarize the students with the theoretical background and research directions of epigenetics, including the most recent clinical and preventive aspects. Conditions for acceptance of the semester Participation in lectures and practicals is obligatory which is registered. Absences should not exceed 15% (2x45 min). Otherwise signature of grade book is denied. Mid-term exams Written test Making up for missed classes There are no make-up classes. Reading material - Obligatory literature - Literature developed by the Department Educational material uploaded on CooSpace. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 The concept, history and theoretical background of epigenetics I Bérczi Bálint Dániel The concept, history and theoretical background of epigenetics II Bérczi Bálint Dániel DNA-methylation I Dr. Rákosy Zsuzsa DNA-methylation II Dr. Rákosy Zsuzsa Histone variants, -modifications and the chromatin-organisation I Bérczi Bálint Dániel Histone variants, -modifications and the chromatin-organisation II Bérczi Bálint Dániel Regulatory non-coding RNAs I Bérczi Bálint Dániel Regulatory non-coding RNAs II Bérczi Bálint Dániel Clinical and preventive aspects of epigenetics I Dr. Rákosy Zsuzsa Clinical and preventive aspects of epigenetics II Dr. Rákosy Zsuzsa What holds the future for us? I Dr. Kiss István What holds the future for us? II Dr. Kiss István 79 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars 1 2 Epigenetical research methods I Epigenetical research methods II Exam topics/questions CooSpace Participants Bérczi Bálint Dániel (BEBIABT.PTE) 80 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EPR USE OF THE EPR SPECTROSCOPY ON BIOLOGICAL STRUCTURES DR. KORNÉLIA FARKAS-BORBÁS, assistant professor Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 2 Number of hours/semester: 7 lectures + 7 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 2–6 Prerequisites: OAA-BI1 completed Topic The aim of the course is to learn the usual techniques in EPR spectroscopy on different samples, and evaluation of the results obtained. The electron paramagnetic resonance spectroscopy is a method similar to NMR, but deals with the properties of electron spin resonance. The technique provides data on the molecular structure and dynamics of various, e.g. biological systems. The investigation of paramagnetic materials, like free radicals, metals, and special spin-labels help to describe biological systems, e.g. membranes, proteins. Conditions for acceptance of the semester Oral exam Mid-term exams Making up for missed classes Consultation Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature 1. C. P. Poole: Electron Spin Resonance, John Wiley & Sons, New York, 1983 2. Hoppe, N., Lohmann, W., Marke, H., Ziegler, H.: Biophysics, Springer-Verlag, Berlin, 1987 Lectures 1 2 3 4 5 6 7 The basics of EPR Spectroscopy 1. Borbásné Dr. Farkas Kornélia The basics of EPR Spectroscopy 2. Borbásné Dr. Farkas Kornélia The basic features of EPR Spectrometer Borbásné Dr. Farkas Kornélia Spin labels and labeling methods Borbásné Dr. Farkas Kornélia Free radicals - spin trapping Borbásné Dr. Farkas Kornélia Membrane structures and their labeling Borbásné Dr. Farkas Kornélia Other biological structures and their labeling Borbásné Dr. Farkas Kornélia Practices 1 2 3 4 5 6 7 Way of registration, registration and analyze of an EPR spectra 1. Way of registration, registration and analyze of an EPR spectra 2. Measurements of membrane dynamics 1. Measurements of membrane dynamics 2. Labeling and measuring of other biological structures 1. Labeling and measuring of other biological structures 2. Spin trapping 81 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Participants Borbásné Dr. Farkas Kornélia (FAKAAA.T.JPTE), Dr. Dergez Tímea (DETCAA.T.JPTE), Dr. Visegrády Balázs (VIBAAB.T.JPTE) 82 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EUA BASIC PRINCIPLES OF HEALTH CARE PROVISION IN THE EUROPEAN UNION DR. ISTVÁN SZILÁRD, honorary professor Department of Operational Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 2 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 4 – 20 Prerequisites: no prerequisites Topic Hungary, as any other members of the Schengen treaty is challenged by new tasks, requiring harmonized measures and special actions on the field of human resource capacity building for the health care system. Regarding to this we are launching a new training program focusing on three main fields: Health care provision and management within the frame of the European Union; Needs for and conditions of trans-border healthcare in the EU; Health/ public health and mental health aspects of the assistance of most vulnerable groups like ethnic minorities and migrants. With these objectives the course contributes to understand the main conditions and aspects of the health care provision within the EU, including such important issues as the cross-border health care and cross-border mobility of patients, and quality health assistance in a multiethnic, multicultural community. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes Based on individual consultation with the lecturer. Reading material - Obligatory literature - Literature developed by the Department Rechel, B., Mladovsky, P., Devillé, W., Rijks, B., Petrova-Benedict, R. & McKee, M. (eds.): Migration and Health in the European Union, Open University Press, Berkshire 2011 Donev, D., Pavlekovic, G., & Kragelj, L. Z. (eds.): Health Promotion and Disease Prevention, Hans Jacobs Publishing Company, Skopje 2007 Wismar, M., Palm, W., Figures, J., Ernst, K., van Ginneken, E. (eds.): Cross-border Health Care in the European Union. Mapping and Analysing Practices and Policies: European Observatory on Health Systems and Policies, WHO 2011, 2011 - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 Introduction to the European Union: structure of governing bodies; health and health care related policy, legislation. Introduction of DG SANCO and ECDC Dr. Szilárd István Introduction to the European Union: structure of governing bodies; health and health care related policy, legislation. Introduction of DG SANCO and ECDC Dr. Szilárd István Health challenges of the European Union, morbidity and mortality structure, focusing on vulnerable groups: migrants, ethnic minorities Dr. Szilárd István Health challenges of the European Union, morbidity and mortality structure, focusing on vulnerable groups: migrants, ethnic minorities Dr. Szilárd István Trends and epidemiology of chronic, non communicable diseases in the Member States of the European Union Dr. Ternák Gábor Trends and epidemiology of chronic, non communicable diseases in the Member States of the European Union Dr. Ternák Gábor Emerging and re-emerging infectious diseases; rare and tropical diseases in the European Union Dr. Ternák Gábor Emerging and re-emerging infectious diseases; rare and tropical diseases in the European Union Dr. Ternák Gábor 83 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Primary health care (PHC) in the European Union Dr. Szilárd István Primary health care (PHC) in the European Union Dr. Szilárd István Cross-border health care Dr. Goolesorkhi Kia Cross-border health care Dr. Goolesorkhi Kia Migration-related health challenges Dr. Szilárd István Migration-related health challenges Dr. Szilárd István Health care in multicultural environment Dr. Baráth Árpád Health care in multicultural environment Dr. Baráth Árpád Special and current challenges of health care and assistance related to ethnic minorities Dr. Goolesorkhi Kia Special and current challenges of health care and assistance related to ethnic minorities Dr. Goolesorkhi Kia Migrant- and ethnic minority-friendly health care system Dr. Szilárd István Migrant- and ethnic minority-friendly health care system Dr. Szilárd István European Union regulations related to drugs, medicines and vaccination Dr. Katz Zoltán European Union regulations related to drugs, medicines and vaccination Dr. Katz Zoltán The way and conditions of developing, organizing, operating and financing health care in the European Union Dr. Goolesorkhi Kia The way and conditions of developing, organizing, operating and financing health care in the European Union Dr. Goolesorkhi Kia The relation between health care and the economy: occupational health; mobility of workforce and health workforce Dr. Tibold Antal The relation between health care and the economy: occupational health; mobility of workforce and health workforce Dr. Tibold Antal Right based access to the health care: health related human right recommendations and declarations of the European Union Marek Erika Right based access to the health care: health related human right recommendations and declarations of the European Union Marek Erika Practices Seminars Exam topics/questions The exam will be based on the lectures and the recommended readings. Participants 84 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-FTA BASICS OF PHYTOTHERAPY DR. JUDIT PONGRÁCZ, professor Department of Pharmaceutical Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 2 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 200 Prerequisites: no prerequisites Topic The basic knowledge about phytotherapy, the students’ awareness of the phytotherapy or their activities and tasks of the races. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes CooSpace - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 The history of natural medicine, philosophical foundations. The phytotherapy as a natural healing method. Kovácsné Kósa Judit Historical overview of the development of phytotherapy. The location of the phytotherapy within classical methods of Natural Medicine. Kovácsné Kósa Judit The regulation of Natural Medicine. Basic definitions in the phytotherapy. Kovácsné Kósa Judit Herbs I: Rules of collection and storage; Typical quality defects. Kovácsné Kósa Judit Herbs II: Drug Testing; Protected and endangered species. Kovácsné Kósa Judit Healthy food plants, herbs, mushrooms and juices. Kovácsné Kósa Judit Classification by substances I Kovácsné Kósa Judit Classification by substances II Kovácsné Kósa Judit Classification by substances III Kovácsné Kósa Judit Classification by substances IV Kovácsné Kósa Judit Causal and symptomatic treatment in Phytotherapy. Kovácsné Kósa Judit Making prescription. Herbs and their underactions. Kovácsné Kósa Judit Parts of the treatment plan and its practical application. The treatment from ethical perspective. Kovácsné Kósa Judit The priority areas of Phytotherapy: Apitherapy, Aromatherapy and the Bach Flower Therapy. Kovácsné Kósa Judit 85 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions CooSpace Participants 86 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-GSE BASICS OF MEDICAL EQUIPMENT DR. JUDIT PONGRÁCZ, professor Department of Pharmaceutical Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 2 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 150 Prerequisites: no prerequisites Topic The aims of the course to give basic knowledge about the next topics: how can use and prescribing medical equipment. Conditions for acceptance of the semester Completing the test at 51% success. Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes CooSpace - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Definition and classification of medical equipment Kovácsné Kósa Judit Indication of medical equipment Kovácsné Kósa Judit Quality requirements for medical equipment Kovácsné Kósa Judit Proper use of medical equipment; basic hygiene rules Kovácsné Kósa Judit Basics of social insurance Kovácsné Kósa Judit Medical equipment - close to the body Kovácsné Kósa Judit Medical equipment - remote from the body Kovácsné Kósa Judit Application of medical equipment - choose with patient Kovácsné Kósa Judit Compliance of medical equipment Kovácsné Kósa Judit Taking of measurements - the rules Kovácsné Kósa Judit Types of medical equipment in the practice I. - Musculoskeletal disorders and skin Kovácsné Kósa Judit Types of medical equipment in the practice II. - Breast disease and respiratory diseases Kovácsné Kósa Judit Types of medical equipment in the practice III. - Metabolic diseases, circulatory diseases and painkilling Kovácsné Kósa Judit Types of medical equipment in the practice IV. - Gastro-intestinal diseases, diseases of urinary and genital system Kovácsné Kósa Judit 87 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions Participants 88 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-HEV MEDICAL ASPECTS OF HUMAN EVOLUTION DR. LÁSZLÓ MÁRK, associate professor Department of Biochemistry and Medical Chemistry Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 26 lectures + 0 practices + 0 seminars = total of 26 hours Course headcount limitations (min.-max.): 2 – 25 Prerequisites: no prerequisites Topic The course shows the evolutionary aspects of the human anatomy and thinking. The students will learn about evolutionary aspects of the human walk, the development of the human senses, hand and mind. Furthermore, we going see the development of the human social network and culture embedded in human evolution. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams None. Making up for missed classes Not possible. Reading material - Obligatory literature - Literature developed by the Department Lecture slides. - Notes - Recommended literature Kordos L.: New Results of Hominoid Research in the Carpathian Basin, Acta Biologica Szegediensis, 2000 44: 71-74. Martin RD.: Primate Origins and Evolution, Chapman and Hall, London 1990 Smith FH. & Spencer F. (eds.): The Origin of Modern Humans, Alan R. Liss, New York 1984 Szathmáry L.: Humans and Climate Pulsation, Anthrop. Közl., 2002 43: 9-19. Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Introduction. The history of human evolutionary research. Dr. Márk László Introduction. The history of human evolutionary research. Dr. Márk László Evolution of primates and hominidae (Prosimii alrend, Dryopithecus, Ramapithecus, Australopithecusok, Kenyathropus etc.) Dr. Márk László Evolution of primates and hominidae (Prosimii alrend, Dryopithecus, Ramapithecus, Australopithecusok, Kenyathropus etc.) Dr. Márk László Evolution and properties of Rudapithecus hungaricus. Dr. Márk László Evolution and properties of Rudapithecus hungaricus. Dr. Márk László Evolution of the Homo genus. Dr. Márk László Evolution of the Homo genus. Dr. Márk László Archaic Homo sapiens and H. neandertalensis. Dr. Márk László Archaic Homo sapiens and H. neandertalensis. Dr. Márk László Anatomy of Homo sapiens. Dr. Reglődi Dóra Anatomy of Homo sapiens. Dr. Reglődi Dóra 89 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 15 16 17 18 19 20 21 22 23 24 25 26 Bipedalism. The evolution of human walk. Dr. Márk László Bipedalism. The evolution of human walk. Dr. Márk László „Homo habilis”. Evolution of human hand. Dr. Márk László „Homo habilis”. Evolution of human hand. Dr. Márk László Evolution of human senses. Dr. Márk László Evolution of human senses. Dr. Márk László Evolution of the human mind. Dr. Márk László Evolution of the human mind. Dr. Márk László Evolutionary aspects of the social network and the human culture. Dr. Márk László Evolutionary aspects of the social network and the human culture. Dr. Márk László Effects of neolitization and urbanization to the human development. Dr. Márk László Effects of neolitization and urbanization to human development. Dr. Márk László Anatomy and modern civilization. Dr. Reglődi Dóra Anatomy and modern civilization. Dr. Márk László Practices Seminars Exam topics/questions The history of human evolutionary research. Evolution of primates and hominidae (Prosimii alrend, Dryopithecus, Ramapithecus, Australopithecusok, Kenyathropus etc.) Evolution and properties of Rudapithecus hungaricus. Evolution of the Homo genus. Archaic Homo sapiens and H. neandertalensis. Bipedalism. The evolution of human walk. „Homo habilis”. Evolution of human hand. Evolution of human senses. Evolution of the human mind. Evolutionary aspects of the social network and the human culture. Effects of neolitization and urbanization to the human development. Anatomy and modern civilization. Participants 90 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-HSN HUMANITARIAN ASSISTANCE AND ITS MEDICAL AND HEALTH CARE ASPECTS DR. ISTVÁN SZILÁRD, honorary professor Department of Operational Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 2 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 20 Prerequisites: no prerequisites Topic The course introduces the issues concerning humanitarian assistance and the inevitable social and health consequences of such intervention. It examines humanitarian assistance in the framework of international relations, discovers its health, public health, legal and economic aspects and investigates the wider context of international cooperation in development. The course offers an opportunity to understand the practical implementation of humanitarian assistance as well. The current trends and scenes of humanitarian assistance are illustrated by short case-studies in every particular topic. 1. Humanitarian Assistance and International Development Cooperation 2. The Basic Roles of Health Care and Humanitarian Assistance 3. Migration and Humanitarian Assistance 4. Health and Public Health Issues of Host Countries Involved in Mass Migration 5. Healthcare at the Hungarian Refugee Stations, Protected Quarters 6. The Nature of Health Care Concerning Migrants and Multicultural Environment 7. Health Aspects of Humanitarian Tasks Carried Out amongst Ethnic Minorities 8. Occupational Education, Monitoring, Training and if Necessary Rehabilitation of the Humanitarian Caregivers 9. Humanitarian and Human Rights Aspects of Trafficking in Human Beings. Humanitarian Assistance in the Light of International Law, International Politics and International Political Economy 10. The Participants of the Process of Humanitarian Assistance 11. Civil Society Organizations in Humanitarian Assistance 12. Health Care Challenges in Humanitarian Crises 13. Case Study: the Experience Gathered by HBAid in Humanitarian Crises 14. Social Assistance among Homeless People and Drug Addicts Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes Based on independent consultation. Reading material - Obligatory literature - Literature developed by the Department Smillie, Ian, Minear, Larry: The Charity of Nations. Humanitarian Action in a Calculating World, Kumarian Press, Bloomfield 2004 Cahill, Kevin M. (ed.): Human Security for All. A Tribute to Sergio Vieira de Mello, Fordham University Press and The Center for International Health and Cooperation, New York Walker, Peter, Maxwell, Daniel: Shaping the Humanitarian World, Routledge, London 2009 Baráth, Á., Szilárd, I. et al (editor and co-author): Building Healthy Roma Communities. Training Manual, Brussels 2006 IOM Szilárd, I. - Baráth, Á. et al: The Mental Health Aspect of Trafficking in Human Beings. Training Manual, Budapest, 2004 IOM - Notes - Recommended literature Lectures Practices Seminars 1 Humanitarian Assistance and International Development Cooperation The concept of humanitarian assistance: humanitarian crisis, complex crisis. The concept and characteristic features of international development cooperation. The fundamental differences between humanitarian aid and development aid (motivation, objectives, decision making); The formation of the present system of organized aid; International development cooperation as a means of foreign policy. The transition between humanitarian assistance and development 91 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 Humanitarian Assistance and International Development Cooperation The concept of humanitarian assistance: humanitarian crisis, complex crisis. The concept and characteristic features of international development cooperation. The fundamental differences between humanitarian aid and development aid (motivation, objectives, decision making); The formation of the present system of organized aid; International development cooperation as a means of foreign policy. The transition between humanitarian assistance and development The Basic Roles of Health Care and Humanitarian Assistance, its human resource and material conditions for acute cases in far geographical regions. Coordination and completion of on-site aid The Basic Roles of Health Care and Humanitarian Assistance, its human resource and material conditions for acute cases in far geographical regions. Coordination and completion of on-site aid Migration and Humanitarian Assistance The rights of and protection for refugees and IDPs, caring for them, the challenges of setting up and securing provisions for camps Migration and Humanitarian Assistance The rights of and protection for refugees and IDPs, caring for them, the challenges of setting up and securing provisions for camps Health and Public Health Issues of Host Countries Involved in Mass Migration. Prevention of the evolvement of epidemiological clusters, vaccination, public health standards of refugee camps, priority medical evaluation Health and Public Health Issues of Host Countries Involved in Mass Migration. Prevention of the evolvement of epidemiological clusters, vaccination, public health standards of refugee camps, priority medical evaluation Healthcare at the Hungarian Refugee Stations, Protected Quarters: theory and practice of migrant-specific health care (vaccination, health screening tests, etc.) Healthcare at the Hungarian Refugee Stations, Protected Quarters: theory and practice of migrant-specific health care (vaccination, health screening tests, etc.) The Nature of Health Care Concerning Migrants and Multicultural Environment (the role of language, religion, beliefs in healthcare The Nature of Health Care Concerning Migrants and Multicultural Environment (the role of language, religion, beliefs in healthcare Health Aspects of Humanitarian Tasks Carried Out amongst Ethnic Minorities Health Aspects of Humanitarian Tasks Carried Out amongst Ethnic Minorities Occupational Education, Monitoring, Training and if Necessary Rehabilitation of the Humanitarian Caregivers Occupational Education, Monitoring, Training and if Necessary Rehabilitation of the Humanitarian Caregivers Humanitarian and Human Rights Aspects of Trafficking in Human Beings. Humanitarian Assistance in the Light of International Law, of International Politics and of International Political Economy The concept of trafficking in human beings, its victims, an overview of its dimensions and forms, the main points to consider when providing care and rehabilitation assistance in protected homes and during return and reintegration. The principles of humanitarian intervention and assistance in international law; the relevant elements of international humanitarian law; the connection between international human rights and humanitarian aid; the assessment of aid in individual schools of foreign policy; the dilemmas involved in allocating and making humanitarian aid available. The economic dilemmas involved in providing aid. The factors impeding aid from reaching its destination Humanitarian and Human Rights Aspects of Trafficking in Human Beings. Humanitarian Assistance in the Light of International Law, of International Politics and of International Political Economy The concept of trafficking in human beings, its victims, an overview of its dimensions and forms, the main points to consider when providing care and rehabilitation assistance in protected homes and during return and reintegration. The principles of humanitarian intervention and assistance in international law; the relevant elements of international humanitarian law; the connection between international human rights and humanitarian aid; the assessment of aid in individual schools of foreign policy; the dilemmas involved in allocating and making humanitarian aid available. The economic dilemmas involved in providing aid. The factors impeding aid from reaching its destination The Participants of the Process of Humanitarian Assistance The characteristic features of donors involved in humanitarian assistance; the interests and the features characterizing the aid work of some larger donor states; the aid provided by the UNO-family; the aid provided by the European Union, the role of ECHO; the International Committee of the Red Cross, the International Red Cross and Red Crescent Movement as special participants; the role of locally based authorities in providing aid The Participants of the Process of Humanitarian Assistance The characteristic features of donors involved in humanitarian assistance; the interests and the features characterizing the aid work of some larger donor states; the aid provided by the UNO-family; the aid provided by the European Union, the role of ECHO; the International Committee of the Red Cross, the International Red Cross and Red Crescent Movement as special participants; the role of locally based authorities in providing aid Civil Society Organizations in Humanitarian Assistance The types and characteristic features of aid organizations; the tasks and role of local organizations and international aid organizations; the advantages and disadvantages of civil society organizations in contrast with government agencies; planning and strategy at a civil society organization; the decisions made by aid organizations in light of the scarceness of resources. + HBAid case study 92 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 22 23 24 25 26 27 28 Civil Society Organizations in Humanitarian Assistance The types and characteristic features of aid organizations; the tasks and role of local organizations and international aid organizations; the advantages and disadvantages of civil society organizations in contrast with government agencies; planning and strategy at a civil society organization; the decisions made by aid organizations in light of the scarceness of resources. + HBAid case study Health Care Challenges in Humanitarian Crises; case study from the perspective of a volunteering doctor Health Care Challenges in Humanitarian Crises; case study from the perspective of a volunteering doctor Case Study: the Experience Gathered by HBAid in Humanitarian Crises; the lessons learned from and the best practices of international aid and development Case Study: the Experience Gathered by HBAid in Humanitarian Crises; the lessons learned from and the best practices of international aid and development Social Assistance Among Homeless People and Drug Addicts Social Assistance Among Homeless People and Drug Addicts Exam topics/questions The exam will be based on the recommended readings and the lectures. Participants Dr. Baráth Árpád (BAAFABP.PTE), Dr. Szilárd István (SZIQAAP.PTE), Dr. Tibold Antal (TIAMAAF.PTE) 93 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-IZM MOLECULAR BASIS OF MUSCLE FUNCTION DR. DÉNES LŐRINCZY, professor Department of Biophysics Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 36 Prerequisites: no prerequisites Topic The structure of muscle based on light, phase contrast, polarized and electron microscopic observations. Elastic behaviour of passive and active muscle, types of muscle contractions, muscle force-length relationship. Work done by the muscle, muscle efficiency and heat production. Thermoelastic behaviour of muscle. Muscle models based on mechanical and structural investigations. Bioelectrical phenomena, excitation-contraction coupling. Energetics of muscle function, structure of muscle proteins (actin, myosin etc.), analysis of sliding model. Energetic and spectroscopic investigations in the research of molecular dynamic and thermodynamic background of muscle function. Conditions for acceptance of the semester The applicants-in the case of more than one absence (up to maximum three absences in which must not be the consultation or test)-should prepare and will be tested from the missed topics given by the instructor. In the case of more than three absences the course can not be accepted. Mid-term exams Making up for missed classes The applicants-in the case of more than one absence (up to maximum three absences in which must not be the consultation or test)-should prepare and will be tested from the missed topics given by the instructor. Reading material - Obligatory literature - Literature developed by the Department It will be announced at the beginning of the course depending on the possibilities of libraries of Biophysical Department, Faculty of Medicine. A permanent source could be the roaming in the Internet. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 The composition of muscle. Dr. Lőrinczy Dénes The sorts of muscle. Dr. Lőrinczy Dénes The structure of muscle on the basis of light, phasecontrast and polarization microscope. Dr. Lőrinczy Dénes Structure of muscle by ELMI. Dr. Lőrinczy Dénes Sorts of muscle contraction. Dr. Lőrinczy Dénes Elastic behaviour of passive and active muscle. Dr. Lőrinczy Dénes Muscle force and length relationship, Hill`s equation. Dr. Lőrinczy Dénes Work and heat production done by a muscle, efficiency of muscle function. Dr. Lőrinczy Dénes Thermoelastic behaviour of muscle. Dr. Lőrinczy Dénes Muscle models proposed by mechanical and structural investigations. Dr. Lőrinczy Dénes Biochemical basis and energetics of muscle function. Dr. Lőrinczy Dénes 94 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Bioelectrical phenomena. Action potentials. Dr. Lőrinczy Dénes Nernst equation, G-H-K equation. Dr. Lőrinczy Dénes Voltage- and patch-clamp techniques. Dr. Lőrinczy Dénes Excitation-contraction coupling. Dr. Lőrinczy Dénes Structure of muscle proteins (actin and myosin, actomyosin complex). Dr. Lőrinczy Dénes Discussion of sliding model in details (x-ray diffraction). Dr. Lőrinczy Dénes Molecular dynamic background of muscle contraction (EPR spectroscopy) Dr. Lőrinczy Dénes Muscle in the sport and rehabilitation (wellness). Dr. Lőrinczy Dénes Principle of differential scanning calorimetry. Dr. Lőrinczy Dénes Thermodynamic background of muscle contraction (DSC results) Dr. Lőrinczy Dénes Muscle and levers in locomotion. Dr. Lőrinczy Dénes Free consultation from the topics of course (discussion of any problem). Dr. Lőrinczy Dénes Free consultation from the topics of course (discussion of any problem). Dr. Lőrinczy Dénes Written test. Dr. Lőrinczy Dénes Written test. Dr. Lőrinczy Dénes Discussion of the test, final evaluation of the course. Dr. Lőrinczy Dénes Discussion of the test, final evaluation of the course. Dr. Lőrinczy Dénes Practices Seminars Exam topics/questions Written test Participants 95 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-JEA DISEASES OF SIGNAL TRANSDUCTION GYÖRGY SÉTÁLÓ DR. JR., associate professor Department of Medical Biology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 25 Prerequisites: OAA-MB1 completed + OAA-MB2 parallel Topic The topics of signal transduction will be discussed beyond the details of the compulsory course, Molecular cell biology 2. In 14 x 45 minutes special attention is paid to mechanisms that are relevant to diseases. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes It is not possible to make up for missed classes. Reading material - Obligatory literature - Literature developed by the Department Some lecturers using ppt load these up onto the intranet after the class. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction to the topics. Types of inter- and intracellular signaling. ifj. Dr. Sétáló György Second messengers. The cAMP-system in cholera, pertussis and anthrax. Dr. Palkovics Tamás The PKA, PKB and phospholipase C-system. Intracellular calcium. Tumor promotion and the PKC-family. ifj. Dr. Sétáló György Catalytic receptors and their pathological alterations in diseases. ifj. Dr. Sétáló György Insulin signaling and its aspects in certain types of diabetes mellitus. ifj. Dr. Sétáló György Cytokines. NFK-B and inflammation. Dr. Mikó Éva Integrin signaling and metastasis. Dr. Berta Gergely Stress signaling and the consequences of too much stress. Heatshock proteins in signaling. Dr. Bátor Judit Signaling of apoptosis and its alterations in disease. Dr. Pap Marianna Cell-cell and cell-matrix connections and their pathological relevance. ifj. Dr. Sétáló György The role of steroids in signaling and in certain diseases. ifj. Dr. Sétáló György Signaling of the neuromuscular junction and in synapses. Pathological aspects. Dr. Sebők Ágnes Signaling in development. Malformations. Dr. Ábrahám Hajnalka Gabriella Multiple-choice test exam. ifj. Dr. Sétáló György 96 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions Multiple-choice test. Participants 97 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-KEZ BIOLOGICAL BASICS PRACTICE OF HANDWRITING ANALYSIS. APPLICATIONS IN THE MEDICAL DR. ISTVÁN KISS, professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 12 lectures + 0 practices + 2 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: no prerequisites Topic The handwriting may give information on the personality and state of mind of its writer. The course covers the most important areas of handwriting analysis: Formation and development of handwriting, psychological and biological factors of writing, main characteristics of handwriting, basics of handwriting analysis, applications and limitations of graphology. Conditions for acceptance of the semester Participation in lectures and practicals is obligatory which is registered. Absences should not exceed 15% (2x45 min). Otherwise signature of grade book is denied. Mid-term exams Written exam. Making up for missed classes There are no make-up classes. Reading material - Obligatory literature - Literature developed by the Department Educational material uploaded on CooSpace. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Introduction: History of graphology, main applications, its relation with other subjects. I Dr. Kiss István Introduction: History of graphology, main applications, its relation with other subjects. II Dr. Kiss István Neurophysiological basis of handwriting. Dr. Horváth-Sarródi Andrea Development of handwriting, its relation with the psychosocial development. Dr. Horváth-Sarródi Andrea Basics of measurements. Dr. Kiss István Handwriting norms. Dr. Kiss István Characteristics of handwriting I. (Macro- and mesostructure) Dr. Kiss István Characteristics of handwriting II. (Letters) Dr. Kiss István Characteristics of handwriting III. (Binding, microstructural elements) Dr. Kiss István Characteristics of handwriting IV. (Dynamics of handwriting.) Dr. Kiss István Portrait from handwriting. Dr. Horváth-Sarródi Andrea Analysis of drawings. Handwriting of children. Dr. Horváth-Sarródi Andrea 98 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars 1 2 Applied graphology. I Applied graphology. II Exam topics/questions CooSpace Participants Dr. Kiss István (KIIFAD.A.JPTE) 99 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-KFO CAPILLARY ELECTROPHORESIS IN LABORATORY DIAGNOSTICS CSILLA PÁGER, assistant lecturer Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 50 Prerequisites: no prerequisites Topic Capillary electrophoresis in laboratory diagnostic processes are considered to be the most modern separation techniques. Its application in health sciences is obvious. The course deals with the theoretical background and application of the microfluidic methods. Design of capillary electrophoretic experiments. Proteins and small molecules. Electrophoresis of cells. Special applications, chiral separations, microbiological applications. Conditions for acceptance of the semester Oral exam, maximum 2 absences Mid-term exams An assay should be prepared and presented by the students, which will serve as a basis for obtaining a mark at the last occasion of the course. Making up for missed classes According to the faculty rules. Reading material - Obligatory literature - Literature developed by the Department http://aok.pte.hu/bioanalitika/Oktatas/Oktatas.html - Notes - Recommended literature James Landers (ed.): Handbook of Capillary Electrophoresis, CRC Press, 1994 Ann Van Schepdael: Microchip Capillary Electrophoresis Protocols, Springer, 2015 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Evolution of separation methods Páger Csilla Development of new electrophoretic methods Páger Csilla Theory of electrophoresis Páger Csilla Separation modes in electrophoresis Páger Csilla Zone electrophoresis Páger Csilla Isoelectric focusing theory Páger Csilla IEF methodology, sandwich injection Páger Csilla Isotachophoresis Páger Csilla Gel electrophoresis Páger Csilla High resolution analysis of macromolecules Páger Csilla Chiral analysis of drugs Páger Csilla Lab-on-a-chip methodology Páger Csilla 100 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Application in laboratory diagnostics Páger Csilla Coupling with mass spectrometry Páger Csilla Practices Seminars Exam topics/questions Discussion of practical questions after home work. Participants 101 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-KTE DIFFERENT NATIONS’, RELIGIONS’ DIETARY HABITS SCIENCE ASPECTS IN NUTRITIONAL AND HEALTH DR. TÍMEA VARJAS, assistant professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 30 Prerequisites: no prerequisites Topic The eating habits of different nations and landscapes can be completely different from each other, special regard to the used materials and kitchen technology processes. It is necessary to get to know the ideological background of major world religions, fasting and nutritional habits related to different religions, used materials, used kitchen technological procedures, in order to analyze the various dietrelated diseases? Morbidity and mortality indicators in epidemiological and nutritional physiological aspects. The course describes the effect of the various nutritional factors? Impact on the above-mentioned ratios and provides an extracurricular image of the world’s religions? And nations? Nutritional habits. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Exam: test after the last lecture. Re-take exam in the exam period. Making up for missed classes Based on individual consideration Reading material - Obligatory literature - Literature developed by the Department PPT-presentations (CooSpace) - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 The French kitchen, main characteristics, nutritional and health science aspects - epidemiological data Raposa László Bence Overview of the Mediterranean life-philosophy and gastronomy, nutritional and health science aspects Raposa László Bence Anglo-Saxon areas: presentation of the characteristics of the Russian eating habits Raposa László Bence Benelux characteristics, methods of preparing food, nutritional and health science aspects Raposa László Bence Far Eastern cuisine overview, epidemiological aspects Raposa László Bence Scandinavian countries; typical eating habits, nutritional and health science aspects Raposa László Bence American eating habits’; impact on obesity and related illnesses Raposa László Bence Bible and nutrition, the Catholic religion, fasting habits Raposa László Bence Differences between Christian and Christian eating habits Raposa László Bence The Islamic faith and the basics of Islam, Ramadan, the Arabic countries; nutritional habits Raposa László Bence The Jewish religious life, Jewish food Raposa László Bence 102 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 Community of Krishna conscious believers, diet of Krishna conscious believers, the teachings of Ayurveda Raposa László Bence Summary Raposa László Bence Exam, test Raposa László Bence Practices Seminars Exam topics/questions Coospace Participants 103 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-N04 ANATOMICAL TERMINOLOGY GABRIELLA HÁBEL, language teacher Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: no prerequisites Topic The course aims to mediate the basic anatomical terms supporting the studies of Anatomy. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature University Script Donáth, Tibor: Lexicon Anatomiae. Anatomical Dictionary, Semmelweis, Bp. 1999. Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Structure of anatomical terms. Structure of anatomical terms. Body Planes, Anatomical Directions, Surface Features of Bones Body Planes, Anatomical Directions, Surface Features of Bones Anatomical Terminology of the Upper Extremity, Bones, Joints Anatomical Terminology of the Upper Extremity, Bones, Joints Anatomical Terminology of the Scapula and Shoulder Girdle Anatomical Terminology of the Scapula and Shoulder Girdle Anatomical Terminology of the Lower Extremity, Bones, Joints Anatomical Terminology of the Lower Extremity, Bones, Joints Anatomical Terminology of the Pelvic Girdle, Bones, Joints Anatomical Terminology of the Pelvic Girdle, Bones, Joints Test paper 1. Test paper 1. Vertebrae, Sternum, Costae. Terminology of the Vertebral Column Vertebrae, Sternum, Costae. Terminology of the Vertebral Column Anatomical Terminology of the Muscular System Anatomical Terminology of the Muscular System Anatomical Terminology of the Skull. Calvaria, Internal Cranial Base Anatomical Terminology of the Skull. Calvaria, Internal Cranial Base Anatomical Terminology of the Skull. External Cranial Base Anatomical Terminology of the Skull. External Cranial Base Anatomical Terminology of the Skull. Palatine, Sphenoid, Temporal, Occipital Bones Anatomical Terminology of the Skull. Palatine, Sphenoid, Temporal, Occipital Bones Anatomical Terminology of the Skull. Temporomandibular Joint. Cranial Nerves Anatomical Terminology of the Skull. Temporomandibular Joint. Cranial Nerves Test paper 2. Test paper 2. 104 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Exam topics/questions Participants Hábel Gabriella (HAGTAAP.PTE) 105 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-N07 CLINICAL TERMINOLOGY GABRIELLA HÁBEL, language teacher Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: no prerequisites Topic The course aims to mediate the basic clinical terms supporting the clinical studies. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes To be discussed with the course instructor Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature University script Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Structure of clinical terms, synonymous Greek equivalents Structure of clinical terms, synonymous Greek equivalents Case reports in the field of gynecology. Terminology of the female reproductive system Case reports in the field of gynecology. Terminology of the female reproductive system Case reports. Terminology of the male reproductive system Case reports. Terminology of the male reproductive system Clinical terminology of surgical procedures Clinical terminology of surgical procedures Hydrocele and hernia. Case reports in the field of herniorrhaphy. Hydrocele and hernia. Case reports in the field of herniorrhaphy. Differential diagnosis, abdominal pain. Case reports in the field of gastroenterology Differential diagnosis, abdominal pain. Case reports in the field of gastroenterology Test paper 1. Test paper 1. Terminology of the urinary system. Terminology of the urinary system Disorders of the urinary system on the basis of clinical diagnoses. Disorders of the urinary system on the basis of clinical diagnoses. Differential diagnosis. Emesis Differential diagnosis. Emesis Differential diagnosis. Pyrexia, hyperpyrexia, hyperthermia Differential diagnosis. Pyrexia, hyperpyrexia, hyperthermia Terminology of the infectious diseases of childhood Terminology of the infectious diseases of childhood Patient examination. The usage of acronyms and abbreviations in history taking Patient examination. The usage of acronyms and abbreviations in history taking Test paper 2. Test paper 2. 106 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Exam topics/questions Participants Hábel Gabriella (HAGTAAP.PTE) 107 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-NOA NEUROANTHROPOLOGY DR. ÁRPÁD CSATHÓ, associate professor Department of Behavioural Sciences Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 2 – 20 Prerequisites: no prerequisites Topic Culture, mind, and brain: The three main substrates of our self. The basic mechanisms of these substrates as well as the potential interactions between them have been widely investigated by several scientific fields. For example, various research areas of neuroscience and psychology are dedicated to mind and brain connections. In addition, the dynamics and rules of the complex human cultures have been rigorously studied by cultural anthropologists. The potential cultural effects on neuronal functioning, however, received less attention. Therefore, a novel scientific synthesis - Neuroanthropology - has emerged recently with an aim to provide a conceptual background of culture-brain interactions. The course is dedicated to this scientific area. More particular, the course aims to show the different aspects of the main question of „how human culture is embedded in the human brain”. Conditions for acceptance of the semester Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department CooSpace - Notes - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Methods and main theoretical approaches of neuroanthropology Methods and main theoretical approaches of neuroanthropology Culture-sensitive neural substrates Culture-sensitive neural substrates Neural representation of social status hierarchy Neural representation of social status hierarchy Cultural variability in the neural representation of emotions Cultural variability in the neural representation of emotions The neuroanthropology of human empathy The neuroanthropology of human empathy Neuro-cultural interactions behind addiction Neuro-cultural interactions behind addiction Human diet and its neuro-cultural background Human diet and its neuro-cultural background Relationship between culture and mental diseases Relationship between culture and mental diseases The social stress: Effects of cultural and neural processes The social stress: Effects of cultural and neural processes Neuropsychological and cultural mechanisms of language processing Neuropsychological and cultural mechanisms of language processing The neural representation of space and its interaction with culture The neural representation of space and its interaction with culture Neuroeconomy Neuroeconomy 108 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 25 26 27 28 Cultural neuroscience of consciousness Cultural neuroscience of consciousness Human aging: Neuropsychological and cultural mechanisms Human aging: Neuropsychological and cultural mechanisms Exam topics/questions Participants Dr. Csathó Árpád (CSAAAC.T.JPTE) 109 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-PLH THE PLACEBO EFFECT TIBOR SZOLCSÁNYI, assistant professor Department of Behavioural Sciences Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 40 Prerequisites: no prerequisites Topic The use of placebo effect has been an inherent part of medicine for thousands of years, and in the recent decades it has become an inevitable element of medical research due to the introduction of placebo controlled clinical trials. In spite of this fact the research methodology to measure the effectiveness of placebo effect has been clarified only in the last 10-15 years. At the same time researches on the neurochemical mechanisms underlying the placebo effect have gained a new impetus. Currently, therefore, we have a much greater understanding of placebo effect in the context of evidence-based medicine than before, which raises new types of ethical questions as well. During the course we will examine the different aspects of the phenomenon of placebo effect, and the students will gain knowledge of the current research results on the field. The main topics of the course: the history of the use of placebo therapies, the role of placebo effect in medical research, the psycho-social factors that are able to induce placebo effect, neurochemical mechanisms underlying the placebo effect, the ethical implications of the use of placebo effect in medical treatments. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes According to the Code of Studies and Examinations. Reading material - Obligatory literature Franklin G. Miller; Luna Colloca; Ted J. Kaptchuk: The Placebo Effect: Illness and Interpersonal Healing, Perspect Biol Med. 2009 ; 52(4) Damien G. Finniss; Ted J. Kaptchuk; Franklin G. Miller; Fabrizio Benedetti: Biological, Clinical and Ethical Advances of Placebo Effects, Lancet 2010; 375; 686-695 Franklin G. Miller; Donald L. Rosenstein: The Nature and Power of the Placebo Effect, Journal of Clinical Epidemiology 59, 2006; 331-335 Fabrizio Benedetti: Mechanisms of Placebo and Placebo-Related Effects across Diseases and Treatments, Annual Review of Pharmacology and Toxicology, Vol. 48; 2008; 33-60. Jozien M. Bensing; William Verheul: The Silent Healer: The Role of Communication in Placebo Effects, Patient Education and Counseling 80, 2010; 293-299 - Literature developed by the Department Additional materials: CooSpace - Notes - Recommended literature Fabrizio Benedetti: Placebo Effect, Oxford University Press, Oxford, 2009 Lectures Lectures 1 2 3 4 5 Introduction, definitions of placebo effect Dr. Szolcsányi Tibor The use of placebo effect in the history of medicine Dr. Szolcsányi Tibor The use of placebo effect in the context of medical research: the introduction of randomized placebo controlled clinical trials and its consequences Dr. Szolcsányi Tibor The methodological and ethical challenges of placebo research Dr. Szolcsányi Tibor The main forms of placebo effect (expectancy based / classical conditioning / affective modulation) and their effectiveness in different diseases Dr. Szolcsányi Tibor 110 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 6 7 8 9 10 11 12 13 14 The neurochemistry of placebo effect: placebo analgesia Dr. Szolcsányi Tibor The neurochemistry of placebo effect: the cardiovascular and the respiratory system, immune response and hormone secretion, Parkinson disease Dr. Szolcsányi Tibor The neurochemistry of placebo effect: further results Dr. Szolcsányi Tibor An overview of the psycho-social factors that are able to induce placebo effect Dr. Szolcsányi Tibor The anthropological and evolutionary background of placebo effect Dr. Szolcsányi Tibor Pain management through psychological interventions and placebo analgesia Dr. Szolcsányi Tibor Ethical implications: how to enhance the placebo effect through improving the physician-patient relationship Dr. Szolcsányi Tibor Ethical implications: the possible role of complementary medicine in the enhancement of placebo effect Dr. Szolcsányi Tibor Written test Dr. Szolcsányi Tibor Practices Seminars Exam topics/questions Participants 111 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-POG POPULATION GENETICS AND THE PRACTICAL USAGE OF ITS RESULTS DR. TÍMEA VARJAS, assistant professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 12 lectures + 2 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 4 – 30 Prerequisites: no prerequisites Topic Students can learn about the theory and methods of population genetics then we show the practical aspects of determining the genetic variations in different human populations. We will show international test series, whose results helped population genetics to be used in mapping of rare diseases, origin research, determining migration patterns and forensic medicine as well and we can determine the relationship between the spectrum of disease and genetic characteristics of different ethnic groups Conditions for acceptance of the semester Absences should not exceed 15% of lectures and practicals (2x45 min). Otherwise signature of grade book is denied. Examination: written test Mid-term exams Mid-term exams Exam: test after the last lecture. Re-take exam in the exam period. Making up for missed classes Based on individual consideration Reading material - Obligatory literature - Literature developed by the Department PPT-presentations (CooSpace) - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 Basic concepts of population genetic: selection, migration, genetic drift Bérczi Bálint Dániel The Hardy-Weinberg principle (equilibrium model) Bérczi Bálint Dániel The results of The Human Genome Project, Human Diversity Program and the Genographic Project Bérczi Bálint Dániel Ethical issues of DNA banking Bérczi Bálint Dániel Determination of genetic distance by examination of the classic genetic markers Bérczi Bálint Dániel The mtDNA as genetic marker - mitochondrial Eve Dr. Varjas Tímea The chromosome Y as a tool for the population’s origin determination Dr. Varjas Tímea Archeogenetic (studies) (examinations), examination of microorganism in fossil bones and mummies Bérczi Bálint Dániel Usage of population genetics in Forensic Medicine I Bérczi Bálint Dániel Usage of population genetics in Forensic Medicine II Bérczi Bálint Dániel 112 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 Spectrum of diseases in different ethnic groups Dr. Varjas Tímea Genetic structure of local ethnic groups / populations Dr. Varjas Tímea Practices 1 2 Technical background of population genetics researches I Technical background of population genetics researches II Seminars Exam topics/questions Coospace Participants Bérczi Bálint Dániel (BEBIABT.PTE) 113 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-ROE HEALTH STATUS AND HEALTH CARE TASKS AND POSSIBILITIES) OF ETHNIC MINORITIES IN THE EU (CHALLENGES, DR. ISTVÁN SZILÁRD, honorary professor Department of Operational Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 2 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 4 – 20 Prerequisites: no prerequisites Topic European ethnic minorities like Roma and in particular, women, children and elderly are exposed to a range of specific health-related problems and often lack access to sufficient health care services. Significant gap exists between these minority communities and the majority populations. Their life expectancy is considerably below of the national averages. In Slovakia, for instance, the life expectancy of Roma women is 17 years less than for the majority of the population; for men, it is 13 years less. In addition to physical health problems, there is insufficient awareness of health issues (both physical and mental), underdeveloped health literacy among the Roma, with preventive care or behaviour often completely ignored and health education/ health promotion nonexistent. All these are challenging seriously the entire society including the health care providers with a special emphasize, how to close the existing serious gap. This is why in the focus of WHO health strategy of this decade is „tackling health inequalities”. Acting successfully in this field-beside the humanitarian obligation-there is a need for new, special knowledge and skills like cultural competence in the health care, community level health promotion in multicultural environment. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes Based on individual consultation with the lecturer. Reading material - Obligatory literature - Literature developed by the Department Baráth Árpád, Agnieszka Gajewska, Ailsa Jones, Slavomira Macakova, Florin Moisa, Martina Ondrusová and Szilárd István: Building Healthy Roma Communities (in Hungarian-English) IOM 2007 Marie Dauvrin: Cultural Competence in Health Care: Challenging Inequalities, Involving Institutions Institute of Health and Society 2013 - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 Introduction: ethnic minorities in the EU, related EU policy Dr. Szilárd István Introduction: ethnic minorities in the EU, related EU policy Dr. Szilárd István Origin of Gypsies, History of Gypsies. Ethnic minorities in Hungary and in Europe. Dr. Kiss Zsuzsanna Origin of Gypsies, History of Gypsies. Ethnic minorities in Hungary and in Europe. Dr. Kiss Zsuzsanna Identification of Roma/Gypsy people and its difficulties. Demographic characteristics of the Roma and other minority populations. Dr. Kiss Zsuzsanna Identification of Roma/Gypsy people and its difficulties. Demographic characteristics of the Roma and other minority populations. Dr. Kiss Zsuzsanna Certain important epidemiological indicators. Health inequalities. Dr. Kiss Zsuzsanna Certain important epidemiological indicators. Health inequalities. Dr. Kiss Zsuzsanna 114 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Health culture of Roma communities Dr. Baráth Árpád Health culture of Roma communities Dr. Baráth Árpád Health determinants Dr. Kiss István Health determinants Dr. Kiss István WHO Marmot Report: Social determinants of health-tackling health inequalities Dr. Szilárd István WHO Marmot Report: Social determinants of health-tackling health inequalities Dr. Szilárd István Health characteristics of Roma and other large ethnic communities versus the majority society Dr. Katz Zoltán Health characteristics of Roma and other large ethnic communities versus the majority society Dr. Katz Zoltán Role of genetic factors on the health status of minorities. Dr. Kiss István Role of genetic factors on the health status of minorities. Dr. Kiss István Role of environmental and lifestyle factors on the health status of minorities. Dr. Kiss Zsuzsanna Role of environmental and lifestyle factors on the health status of minorities. Dr. Kiss Zsuzsanna Community level health promotion-theory, examples, contradictions and new endowers Marek Erika Community level health promotion-theory, examples, contradictions and new endowers Marek Erika Health promotion in ethnic minorities’ communities: the importance of cultural competence in health promotion interventions Dr. Szilárd István Health promotion in ethnic minorities’ communities: the importance of cultural competence in health promotion interventions Dr. Szilárd István Multicultural competence compliance Dr. Baráth Árpád Multicultural competence compliance Dr. Baráth Árpád Summary Dr. Szilárd István Exam Dr. Szilárd István Practices Seminars Exam topics/questions The exam will be based on the lectures and the recommended readings. Participants 115 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-SL2 STANFORD LECTURES II: BEHAVIOURAL GENETICS DR. RÓBERT MÁTICS, assistant professor Department of Pathophysiology and Gerontology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 2 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 1 – 10 Prerequisites: OAF-SL1 completed Topic Prof Robert Sapolsky has a course on behavioural genetics on Stanford University. The 2010 lectures are freely available on the internet. Our course is based on the idea that by hearing a ca. 45-60 min long speech given there, we discuss the facts and hypotheses heard. The expansion and/or integration of this new knowledge is a key goal of the course. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams There’ll be a written exam at the last week’s session about the whole topics discussed in the semester. Making up for missed classes Make-up classes are possible if needed, we’ll have to make appointments. Reading material - Obligatory literature No compulsory books or readings. - Literature developed by the Department Handouts will be given. - Notes The extended notes by Prof Sapolsky are available from me. - Recommended literature Evolution of Behavior Axelrod R, Hamilton WD: The Evolution of Cooperation, Science 211, 1981 1390-1396. Classic paper on the subject. Pool, R: Putting Game Theory to the Test, Science 267, 1995 1591-1593. Going from sociobiological theory to actual field data. Morrell V: Genes versus Teams: Weighing Group Tactics in Evolution, Science 273, 739. 1996 A consideration of the contemporary version of group selection. Kerr B et al.: Local Dispersal Promotes Biodiversity in a Real-life Game of Rock-paper-scissors, Nature 418 171, 2002 This shows game theory being played out in an unlikely species. Just read the abstract. Semmann D et al.: Volunteering Leads to Rock-paper-scissors Dynamics in a Public Goods Game, Nature 425 390, 2003 If you’re really into game theory stuff, this paper shows the rock-paper-scissors in humans. It’s pretty thick going thought, so not for the rookie (i.e., not required). Lectures 1 2 3 4 5 6 7 General Introduction Dr. Mátics Róbert General Introduction Dr. Mátics Róbert Twin studies Dr. Mátics Róbert Twin studies, discussion Dr. Mátics Róbert IQ and birth order Dr. Mátics Róbert IQ and birth order, discussion Dr. Mátics Róbert Recognizing relatives: cellular level Dr. Mátics Róbert 116 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Recognizing relatives: cellular level, discussion Dr. Mátics Róbert Recognizing relatives: social anosmia Dr. Mátics Róbert Recognizing relatives: social anosmia, discussion Dr. Mátics Róbert Recognizing Relatives: intrasexual conflicts Dr. Mátics Róbert Recognizing Relatives: intrasexual conflicts, discussion Dr. Mátics Róbert Human Sexual Behaviour: proximal and distal causes Dr. Mátics Róbert Human Sexual Behaviour: proximal and distal causes, discussion Dr. Mátics Róbert Human Sexual Behaviour: female orgasm Dr. Mátics Róbert Human Sexual Behaviour: female orgasm, discussion Dr. Mátics Róbert Human Sexual Behaviour: non-reproductive sex Dr. Mátics Róbert Human Sexual Behaviour: non-reproductive sex, discussion Dr. Mátics Róbert Human Sexual Behaviour: human-specific patterns Dr. Mátics Róbert Human Sexual Behaviour: human-specific patterns, discussion Dr. Mátics Róbert Human sexual behaviour: reproductive arrest Dr. Mátics Róbert Human sexual behaviour: reproductive arrest, discussion Dr. Mátics Róbert Aggression: the right kind of violence Dr. Mátics Róbert Aggression: the right kind of violence, discussion Dr. Mátics Róbert Aggression: reconciliation Dr. Mátics Róbert Aggression: reconciliation, discussion Dr. Mátics Róbert Summary, questions, discussion, exam Dr. Mátics Róbert Summary, questions, discussion, exam Dr. Mátics Róbert Practices Seminars Exam topics/questions No such thing. Participants 117 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-SMP PATHOLOGY OF THE CELL NUCLEUS DR. LÁSZLÓ KOMÁROMY, associate professor Department of Medical Biology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 1– Prerequisites: OAA-MB1 completed Topic The main significance of this course to demonstrate a basic knowledge of cell pathology which is giving fundamental information for preclinical and clinical subjects. The other goal is to demonstrate the results of ultrastructural morphology and molecular biology at cellpathological level. The course is discussing the functional-morphological changes and alterations of cell nucleus components in different pathological conditions (including the effect of therapeutical procedures). The changes and alterations are estimated as a results of diseases or experimental pathological procedures and methods. The functional-morphological changes are estimated and analyzed on the basis of molecular biological processes. The lectures are summarizing in short the main changes of cytoplasmic structures in the different pathological conditions. The course pays attention to functional morphological changes appearing in the tumor cells especially. Conditions for acceptance of the semester 25% absences are allowed and successful exam. Mid-term exams Making up for missed classes None. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Ghadially, F.N.: Ultrastructural Pathology of the Cell and Matrix Constantinides, P.: Ultrastructural Pathology Cooper, G.M.: The Cell. A Molecular Approach Szeberényi J., Komáromy L. (editors): Molecular Cell Biology Laboratory Manual Szeberényi J.: Experiments in Molecular Cell Biology Relevant publications (given during the course) and hand-outs of lectures. Lectures 1 2 3 4 5 6 7 8 9 10 Methods of functional morphology. General outlines Light microscopical techniques 1 Dr. Komáromy László Methods of functional morphology. General outlines Light microscopical techniques 2 Dr. Komáromy László Methods of functional morphology. General outlines. Electron microscopic techniques 1 Dr. Komáromy László Methods of functional morphology. General outlines. Electron microscopic techniques 2 Dr. Komáromy László Ultrastructure of nuclear periphery 1 Dr. Komáromy László Ultrastructure of nuclear periphery 2 Dr. Komáromy László Protein import to the cell nucleus (regulation and troubles) 1 Dr. Komáromy László Protein import to the cell nucleus (regulation and troubles) 2 Dr. Komáromy László RNA export to cytoplasm (regulation, troubles) 1 Dr. Komáromy László RNA export to cytoplasm (regulation, troubles) 2 Dr. Komáromy László 118 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 New data of chromatin organization 1 Dr. Komáromy László New data of chromatin organization 2 Dr. Komáromy László Changes of chromatin structures in different pathological conditions 1 Dr. Komáromy László Changes of chromatin structures in different pathological conditions 2 Dr. Komáromy László Semester test 1 Dr. Komáromy László Semester test 2 Dr. Komáromy László Alterations of nuclear matrix 1 Dr. Komáromy László Alterations of nuclear matrix 2 Dr. Komáromy László Changes and alterations in structure and function of nucleoli in different pathological conditions 1 Dr. Komáromy László Changes and alterations in structure and function of nucleoli in different pathological conditions 2 Dr. Komáromy László Effects of antimetabolites and cytostatic molecules on the nuclear and nucleolar structures 1 Dr. Komáromy László Effects of antimetabolites and cytostatic molecules on the nuclear and nucleolar structures 2 Dr. Komáromy László Virus induced alterations in the cell nucleus 1 Dr. Komáromy László Virus induced alterations in the cell nucleus 2 Dr. Komáromy László Ultrastructure of apoptotic cells 1 Dr. Komáromy László Ultrastructure of apoptotic cells 2 Dr. Komáromy László Final test 1 Dr. Komáromy László Final test 2 Dr. Komáromy László Practices Seminars Exam topics/questions Multiple-choice test. Participants 119 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-VB2 HOW TO TAKE THE EXAM IN MOLECULAR CELL BIOLOGY? 2 DR. GERGELY BERTA, assistant professor Department of Medical Biology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 100 Prerequisites: no prerequisites Topic The objective of this course is to imitate the oral exam situation of Molecular Cell Biology (MCB) in a small-group-discussion setting. The list of exam question of MCB will be followed during the course: each time 4-5 students of the 20-25 member class will be examined with one question for each examinee. The examiner is one of the instructors/ professors of the Department who conducts and grades the examination the same way as on „real” exams. All the examiners of the Department will be involved, in a rotation system. The aim of the course is to make students familiar with the stressful atmosphere of oral exams. Only students ready to be exposed to the exam situation week-after-week are invited to take this course. Conditions for acceptance of the semester The grade is determined by continuous performance evaluation. Maximum absences: 4. Mid-term exams Making up for missed classes No possibility to make up for missed classes. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Cooper: The Cell. A Molecular Approach. József Szeberényi-László Komáromy: Molecular Cell Biology Syllabus Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Orientation Exam questions 58-60, L11 Exam questions 61-64 Exam questions 65-67, L12 Exam questions 68-70, L13 Exam questions 71-73, L14 Exam questions 74-76, L15 Exam questions 77-79, L16 Exam questions 80-82, L17 Exam questions 83-84, L18 Exam questions 85-87, L19 Exam questions 88-91 Exam questions 92-94, L20 Exam questions 95-97 Exam topics/questions http://www.pote.hu/run/download2.php?idf=253&nyelv=eng Participants Dr. Pap Marianna (PAMFAAO.PTE), Dr. Szeberényi József (SZJGACO.PTE), ifj. Dr. Sétáló György (SEGMAAO.PTE) 120 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-VVE VACCINATION, ANTI-VACCINATION MOVEMENTS: DO MORE HARM THAN GOOD DR. KATALIN SZENDI, assistant lecturer Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 2 Number of hours/semester: 12 lectures + 2 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: no prerequisites Topic Vaccination belongs to one of the most successful modern health care programmes that decreased significantly the number of severe infectious diseases. In today’s world experts are unable to compete with the media. Several delusions circulate infiltrating the public opinion related to vaccines. The most susceptible target audience of these beliefs are the half-educated laymen who believe in the media created pseudoscience. The activity of stubborn anti-vaccine minorities can be dangerous because that may open up new chances of the spread of infectious diseases. The objective of the course is to deepen the knowledge of vaccinations concerning the background, benefits, achievements and failures, and the course also serves as a thought provoking initiation for practitioners relating to possible actions against the anti-vaccination movements. Conditions for acceptance of the semester Participation in lectures and practicals is obligatory which is registered. Absences should not exceed 15% (2x45 min). Otherwise signature of grade book is denied. Mid-term exams Written test on the 14th week. Making up for missed classes There are no make-up classes. Reading material - Obligatory literature - Literature developed by the Department Educational material uploaded on CooSpace. - Notes - Recommended literature Stanley A. Plotkin. History of Vaccine Development. Springer 2011. Vaccine Fact Book 2013. http://www.phrma.org/sites/default/files/pdf/PhRMA_Vaccine_FactBook_2013.pdf WHO, UNICEF, World Bank. State of the world’s vaccines and immunization, 3rd ed., Geneva, World Health Organization, 2009. Lectures 1 2 3 4 5 6 7 History of vaccines and anti-vaccination movements Dr. Szendi Katalin Epidemiology of infectious diseases, morbidity and mortality rates before and after vaccine introduction. Is there any benefit of vaccination? Dr. Szendi Katalin Epidemiological studies on vaccination, are there any at all? Dr. Szendi Katalin Morbidity, mortality, incidence, prevalence. Statistics, data availability, official sources. Are there enough and reliable data to prove the effectiveness or safety of vaccines? Dr. Szendi Katalin Groups of vaccinations. Why are they compulsory? Dr. Szendi Katalin Types of vaccinations. Are there any unnecessary ones (e.g. BCG)? Is it possible that the only purpose of the pharmaceutical industry is to increase their profits? Dr. Szendi Katalin The function of vaccination, types of immunity. Is artificial induction of immunity good for our immune system? Does it result in more benefits if the diseases are fought off in a natural way? Dr. Szendi Katalin 121 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 8 9 10 11 12 The efficiency of vaccines. Do the European countries with better health indicators also have better epidemiological situation than Hungary? Questions of herd immunity. Dr. Szendi Katalin Vaccine effectiveness. Are there any positive health effects, or just does the government want to make us believe in counterfeit statistical data? Dr. Szendi Katalin Vaccination safety, components. Are the ingredients in vaccines dangerous? Do they cause any harm to health? Diversity of conspiracy theories. Dr. Szendi Katalin Risks of vaccines, vaccination health hazards. Do the vaccines do more harm than good? MMR and autism. Mercury and autism. Aluminium and autism. Dr. Szendi Katalin Legal background. The legal regulation of vaccines. The pros and cons of compulsory vaccination. What is the point of it? The reason for the existence of free choice. Dr. Szendi Katalin Practices 1 2 Anti-vaccination activities in Hungary and abroad. Do we have to deal with the anti-vaccination movements? Anti-vaccination movements, hazards, duties. Psychology of the antivaccination attitudes. Seminars Exam topics/questions CooSpace Participants Dr. Szendi Katalin (SZKFAPO.PTE) 122 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-APK PREPARATION OF ANATOMICAL DEMONSTRATION MATERIAL DR. PÉTER KISS, assistant professor Department of Anatomy Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ both semesters semester ▪ recommended semester: 3 Number of hours/semester: 0 lectures + 14 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1–8 Prerequisites: OAA-AA1 completed + OAA-SF1 completed Topic In the course will be made anatomical preparations, for example preparations of head, joints, limbs, pharynx, larynx, lesser pelvic. Students with manual skills are preferred. Each student has to dissect 1 preparation during 12 course hours (4x3 hours), and to present it at the end of the course. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes Absences are individually made up. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction Preparation Preparation Preparation Preparation Preparation Preparation Preparation Preparation Preparation Preparation Preparation Preparation Evaluation of the preparation Seminars Exam topics/questions Participants Dr. Gaszner Balázs (GABFADO.PTE), Dr. Kiss Péter (KIPFABO.PTE) 123 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-BKF BIOCHEMISTRY - QUESTIONS AND ANSWERS DR. ZOLTÁN BERENTE, associate professor Department of Biochemistry and Medical Chemistry Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5– Prerequisites: no prerequisites Topic The course is aimed to support the successful accomplishment of the semester exam of the compulsory course „Biochemistry” (and in part that of the final exam „Medical Biochemistry”). In the classroom the brief summary of the theory related to the actual topic will be followed by discussing explicit questions (multiple choice and open questions as well) in order to deepen the understanding of the material along with the preparation for the written exam. In order to help preparation the topics of this course will discuss the lectures and practices of the main course, but shifted in time. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes On the judgement of the course director Reading material - Obligatory literature - Literature developed by the Department Lecture slideshows on CooSpace - Notes - Recommended literature http://bcs.whfreeman.com/lehninger5e - Interactive Quizzes http://bcs.whfreemn.com/berg7e - Online Quizzing T.A. Swanson, S.I. Kim, M.J. Glucksman: Biochemistry, Molecular Biology & Genetics, 5th editions, Lippincott Williams & Wilkins 2010 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Introduction Dr. Berente Zoltán Biomolecules: The Building Blocks of Life Dr. Berente Zoltán Structure and Function of Proteins Dr. Jakus Péter Enzymes Dr. Jakus Péter Enzyme Inhibitions I Dr. Berente Zoltán Enzyme inhibitions II Dr. Berente Zoltán Biodegradation of Carbohydrates Nagyné Dr. Kiss Gyöngyi Biosynthesis of Carbohydrates Nagyné Dr. Kiss Gyöngyi Regulation of Carbohydrate Metabolism Dr. Kovács Krisztina Molecular Background of the Disorders of Carbohydrate Metabolism Dr. Kovács Krisztina Biodegradation of Lipids Dr. Tapodi Antal Biosynthesis of Lipids Dr. Tapodi Antal 124 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Regulation of Lipid Metabolism Dr. Lengyel Anna Molecular Background of the Disorders of Lipid Metabolism Dr. Lengyel Anna Amino Acid Metabolism Dr. Debreceni Balázs Nucleotide Metabolism Dr. Debreceni Balázs DNA Replication Dr. Tapodi Antal DNA Repair Dr. Tapodi Antal RNA Synthesis Dr. Veres Balázs Viruses, Retroviruses, Small RNA Molecules Dr. Veres Balázs Protein Synthesis: Participants and Mechanism Dr. Berente Zoltán Regulation of Protein Synthesis Dr. Berente Zoltán Regulation of Gene Expression I Dr. Veres Balázs Regulation of Gene Expression II Dr. Veres Balázs Concerted Hormonal Regulation of Metabolism I Dr. Kovács Krisztina Concerted Hormonal Regulation of Metabolism II Dr. Kovács Krisztina Test Dr. Berente Zoltán Test Dr. Berente Zoltán Practices Seminars Exam topics/questions The semester test questions will be selected from the problems discussed in the classroom. Participants 125 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-EFI ELECTROPHYSIOLOGY DR. GÁBOR JANDÓ, associate professor Department of Physiology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1– Prerequisites: OAA-BI1 completed + OAA-OK2 completed Topic The interpretation of the electrical signals from patients is not merely a matter of memorizing a few characteristic pictures; there are many unusual variations and combinations of these phenomena which must be studied, analyzed, and correlated one with another and with other available data before any definite conclusion is possible. These situations demand some acquaintance with the electrical and physiologic principles by which they are determined. The purpose of the course is to understand the origin of the electrical signals that can be recorded from excitable living tissues, the basic properties of their behavior, the main physical and physiological processes by which these signals (action potential, ECG, EEG, event related potentials, R triggered potentials, field potentials, intracellular and extracellular single unit recording) are determined. The course includes the discussion of the physical basis of electricity, resting potential, passive and active properties of the excitable membrane, voltage and ligand gated ion channels, realistic and abstract neuronal network models, the nature of the intra and extracellular signals. The origin and the physiological significance of the diagnostically important electrical signals (ECG, EEG, EMG, VEP) will also be discussed, some clinically relevant topic will also be touched. Conditions for acceptance of the semester Acceptance: 3 absences out of 8 classes is allowed. Exam: oral exam Mid-term exams Making up for missed classes Not possible Reading material - Obligatory literature - Literature developed by the Department The course material will be available on a CD. Students are freely allowed to copy the course CD. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 Electrophysics 1 Dr. Jandó Gábor Electrophysics 2 Dr. Jandó Gábor Excitable membrane 1 Dr. Jandó Gábor Excitable membrane 2 Dr. Jandó Gábor Membrane potential 1 Dr. Jandó Gábor Membrane potential 2 Dr. Jandó Gábor Action potential, field potential 1 Dr. Jandó Gábor Action potential, field potential 2 Dr. Jandó Gábor ECG basics 1 Dr. Jandó Gábor ECG basics 2 Dr. Jandó Gábor 126 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 ECG interpretation 1 Dr. Jandó Gábor ECG interpretation 2 Dr. Jandó Gábor EEG - VEP 1 Dr. Jandó Gábor EEG - VEP 2 Dr. Jandó Gábor Practices Seminars Exam topics/questions Students are allowed to select the most preferred topic of the course and must be prepared for the exam from that topic only. Five-ten shortly answerable questions will be asked from that topic, the mark will be established on the basis of correct answers. Topic list: 1. Physical basis of electrophysiology, amplifiers, leads 2. Passive physiological properties of the neuron 3. Resting potential, action potential, HH model and patch-clamp technique 4. Modeling brain functions: realistic, abstract models, artificial intelligence 5. ECG basics 6. Interpretation of ECG 7. Electroencephalograpy and Event Related Potentials 8. Visual Evoked Potentials Participants 127 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-EHS HUNGER, SATIETY AND DISTURBANCES OF BODY WEIGHT REGULATION DR. LÁSZLÓ LÉNÁRD, professor Department of Physiology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAA-BI2 completed + OAA-MB2 completed Topic Based on recent results, feeding related physiological and pathophysiological mechanisms will be discussed. Students will be trained to understand these mechanisms. The knowledge based on this course will highly contribute to better understanding further clinical studies on human diseases. Peripheral and central mechanisms of hunger, satiety, salt appetite and body weight regulation will be discussed. Lectures will include the following topics: Neural and humoral processes. Peripheral and central glucose-monitoring system. The role of neuropeptides in the control of feeding and hydromineral balance. Pathological processes: obesity, bulimia, anorexia. Conditions for acceptance of the semester Written exams. Absence from no more than 25% of the lectures. Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department - Notes Notes taken at the lectures. - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Basic parameters: caloric intake, energy expenditure, measurement of food and water intake, body weight and body mass index. Body weight curves during development, adulthood and senescence. Dr. Lénárd László I Peripheral and central mechanisms of body weight regulation. Dr. Lénárd László I Endocrine mechanisms: the role of different hormones. Dr. Lénárd László I Body weight loss, obesity. Long run pathological consequences of obesity. Dr. Lénárd László I Hunger and satiety. Motivational mechanisms. Overeating, rejection. Dr. Lénárd László I Hypothalamic dual centers. The role of limbic system in hunger and satiety. Dr. Lénárd László I Peripheral glucose related signals. The central glucose monitoring system. Dr. Lénárd László I Food rewarded learning, the role of reinforcement. Aversive learning, the role of conditioned taste aversion in feeding habits. Dr. Lénárd László I The sight, odor, taste and texture of foods and their detection in the limbic system. Ingestive and rejective mimetic responses and their genetic determination. Dr. Lénárd László I The role of monoamines in the regulation of feeding. Similarities of food rewarded learning and addictive behavior. The role of dopamine and neuropeptides. Dr. Lénárd László I Orexigenic and anorexigenic neuropeptides. Dr. Lénárd László I The role of the central angiotensinergic system in drinking and hydromineral balance. Dr. Lénárd László I 128 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Childhood obesity and cognitive processes. Dr. Lénárd László I Anorexia nervosa, bulimia and binge eating. Clinical relevance of animal experiments Dr. Lénárd László I Practices Seminars Exam topics/questions Participants 129 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-EPS HEALTH PSYCHOLOGY DR. JÁNOS KÁLLAI, professor Department of Behavioural Sciences Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ both semesters semester ▪ recommended semester: 3 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 16 Prerequisites: no prerequisites Topic Health psychology is concerned with the study of psychological processes related to health, illness and health care. It provides a theoretical and practical health-focused approach to people’s well-being. Health psychology studies behavioral factors that influence the health conditions and maintenance of health. Addresses the issues of health promotion, prevention, life events, coping and social support. Deals with the adjustment processes and quality of life in chronic illness, hospitalization and medical care. Furthermore, health psychology emphasizes the importance of the health of health care providers, the prevention of burn out and other professional-related risks. Conditions for acceptance of the semester According to the Code of Studies and Examination. Mid-term exams PowerPoint presentation of a choosen topic. Written exam. Making up for missed classes Additional presentation. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Csabai-Molnár: Health, Illness and Care. Springer, Bp., 2000. Kaptein A., Weinman, J.: Health Psychology, BPS Blackwell, 2004. Camis, P.M., Knight, S.J.: Clinical Handbook of Health Psychology, Hogrefe and Huber, 2004. Friedman H.S., Cohen Silver, R.: Foundations of Health Psychology, Oxford, 2007. Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 Theories and development of health. Health believes and attributions. Healthy personality Theories and development of health. Health believes and attributions. Healthy personality Concepts of health psychology, positive thinking Concepts of health psychology, positive thinking Physician role, patient role, competencies in the health psychology paradigm Physician role, patient role, competencies in the health psychology paradigm Stress and health. Primary prevention Stress and health. Primary prevention Coping, problem-focused and emotion-focused coping Coping, problem-focused and emotion-focused coping Ageing, life-span and health Ageing, life-span and health Gender issues, culture and health Gender issues, culture and health Life events, health and illness, crisis, social support Life events, health and illness, crisis, social support Relaxation and other stress-management methods Relaxation and other stress-management methods 130 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 19 20 21 22 23 24 25 26 27 28 Adjustment to chronic illness. Patients’ understanding and compliance Adjustment to chronic illness. Patients’ understanding and compliance Quality of life and psychological interventions in chronic illness Quality of life and psychological interventions in chronic illness Hospitalization and stressful medical procedures Hospitalization and stressful medical procedures Health of medical students, professional socialization as a source of stress Health of medical students, professional socialization as a source of stress Health of health care professionals: prevention of burn out. Health promotion at workplace Health of health care professionals: prevention of burn out. Health promotion at workplace. Exam topics/questions Participants Dr. Kállai János (KAJFAEP.PTE), Dr. Varga József (VAJGABO.PTE) 131 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-H3A MEDICAL HUNGARIAN 3A - BASICS OF MEDICAL COMMUNICATION DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OAE-H3B parallel + OAE-H2A completed Topic This course in devoted to the acquisition of language and communicative functions of the basic history taking process. Conditions for acceptance of the semester Participation in class work is obligatory. In case absences exceed 25% of total class time, the course will be regarded as uncompleted. In the case of absences up to 25% of total class time, oral examination will have to be taken Mid-term exams Making up for missed classes Participation in class work is obligatory. In case absences exceed 25% of total class time, the course will be regarded as uncompleted. In the case of absences up to 25% of total class time, oral examination will have to be taken. Reading material - Obligatory literature - Literature developed by the Department Mária Győrffy: English for Doctors, Idióma Bt., Pécs, 2001 – can be purchased in the Department - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Family History, social history and previous diseases Complaint and Pain Headache, dizziness, perspiration, nausea, vomiting Vision, shortness of breath, cough Heart complaints, appetite Stool, urine Stool, urine Shivering, fever, oedema Blood Frequent diseases Neck and thyroid blend Oesophagus, stomach, gall bladder Bowel diseases, cardiovascular diseases Medications Medications Test 1 Gynecology Gynecology Urology Urology Surgery and traumatology, Orthopaedic surgery Surgery and traumatology, Orthopaedic surgery Neurology Neurology Consolidation Consolidation Test 2 Consolidation 132 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Participants Dr. Hegedűs Anita (HEAAAA.B.JPTE), Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE), Dr. Warta Vilmos (WAVEAB.B.JPTE), Eklicsné Dr. Lepenye Katalin (EKLAXA.B.JPTE), Hild Gabriella (MAGAAD.B.JPTE), Horváth Lilla Anita (HOLFABP..PTE), Kurdiné Molnár Eszter (KUMPAAK.PTE), Lokodiné Szolcsányi Judit (LOSIAAB.PTE), Mészégetőné Halmos Éva (MEHHABE.PTE), Móriczné Győrffy Mária (MOGPAAP.PTE), Nagy Gabriella (NAGMAAO.PTE), Ronczykné Berta Anikó (BEAAAI.B.JPTE), Szántóné Csongor Alexandra (CSAAAA.B.JPTE), Váradi Katalin (VAKHAAE.PTE) 133 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-H3B MEDICAL HUNGARIAN 3B - MEDICAL COMMUNICATION IN PRACTICE DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OAE-H3A parallel + OAE-H2B completed Topic This course serves the skills development based on language and communicative functions acquired in course 3A. Conditions for acceptance of the semester Participation in class work is obligatory. In case absences exceed 25% of total class time, the course will be regarded as uncompleted. In the case of absences up to 25% of total class time, oral examination will have to be taken Mid-term exams Making up for missed classes Participation is obligatory. Reading material - Obligatory literature - Literature developed by the Department Mária Győrffy: English for Doctors, Idióma Bt., Pécs, 2001 – can be purchased in the Department - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Family history, social history and previous diseases - Listening comprehension and speaking skills Complaint and pain - Listening comprehension and speaking skills Headache, dizziness, perspiration, nausea, vomiting - Listening comprehension and speaking skills Vision, shortness of breath, cough - Listening comprehension and speaking skills Heart complaints, appetite - Listening comprehension and speaking skills Stool, urine-Listening comprehension and speaking skills Stool, urine-Listening comprehension and speaking skills Shivering, fever, oedema - Listening comprehension and speaking skills Blood - Listening comprehension and speaking skills Frequent diseases - Listening comprehension and speaking skills Neck and thyroid blend - Listening comprehension and speaking skills Oesophagus, stomach, gall bladder - Listening comprehension and speaking skills Bowel diseases, cardiovascular diseases-Listening comprehension and speaking skills Medications - Listening comprehension and speaking skills Medications - Listening comprehension and speaking skills Test 1 Gynecology - Listening comprehension and speaking skills Gynecology - Listening comprehension and speaking skills Urology - Listening comprehension and speaking skills Urology - Listening comprehension and speaking skills Surgery and traumatology, Orthopaedic surgery - Listening comprehension and speaking skills Surgery and traumatology, Orthopaedic surgery - Listening comprehension and speaking skills Neurology - Listening comprehension and speaking skills Neurology - Listening comprehension and speaking skills Consolidation Consolidation Test 2 Course evaluation 134 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Participants Dr. Hegedűs Anita (HEAAAA.B.JPTE), Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE), Dr. Warta Vilmos (WAVEAB.B.JPTE), Eklicsné Dr. Lepenye Katalin (EKLAXA.B.JPTE), Hamarné Sávay Judit (HASMAAO.PTE), Hild Gabriella (MAGAAD.B.JPTE), Lokodiné Szolcsányi Judit (LOSIAAB.PTE), Mészégetőné Halmos Éva (MEHHABE.PTE), Móriczné Győrffy Mária (MOGPAAP.PTE), Ronczykné Berta Anikó (BEAAAI.B.JPTE), Szántóné Csongor Alexandra (CSAAAA.B.JPTE), Váradi Katalin (VAKHAAE.PTE) 135 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-HOS HORMONAL REGULATORY MECHANISMS IN HEALTH AND DISEASE DR. MARIETTA VÉRTES M, professor emeritus Department of Physiology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 50 Prerequisites: OAA-MB2 completed Topic The aim of the program is to clarify the role of hormones and hormonal networks in the maintenance of homeostasis and regulation of body processes including reproduction. The lectures attempts to provide an overview of function of hormonal networks and the integrity of nervous and endocrine regulation in human body. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes Oral discussion of given chapter Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Greenstein B.: Endocrinology at a Glance, Springer 1999 Williams Textbook of Endocrinology, 2004 Goodman M: Basic Medical Endocrinology, 2000 Greenspan FS, Baxter JD: Basic and Clinical Endocrinology, 2003 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 Types of hormones. Hormone synthesis, transport Dr. Vértes M Marietta Mechanism of hormone action, hormone receptors Dr. Vértes M Marietta Signal transduction. Regulation of tissue responsiveness to hormones Dr. Vértes M Marietta Endocrine and nervous system relationships Dr. Vértes M Marietta Hypothalamo-hypophyseal tract Dr. Vértes M Marietta Anterior pituitary. Feedback regulation Dr. Vértes M Marietta Principles of hormonal integration. Dr. Vértes M Marietta Hormonal regulation of fuel metabolism. General concepts Dr. Vértes M Marietta Growth hormone and IGF Dr. Vértes M Marietta Hormones of pancreas Dr. Vértes M Marietta Metabolism in diabetes mellitus Dr. Vértes M Marietta Regulatory peptides in the gut Dr. Vértes M Marietta Cortisol Dr. Vértes M Marietta 136 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 14 15 16 17 18 19 20 21 21 23 24 25 26 27 28 Stress and thyroid hormones Dr. Vértes M Marietta Regulation of salt and water balance. General concepts Dr. Vértes M Marietta Hypothalamo-neurophyseal system Dr. Vértes M Marietta Renin-angiotenzin-aldosteron system Dr. Vértes M Marietta Natriuretic hormones Dr. Vértes M Marietta Hormones in pregnancy and during fetal development Dr. Kovács Kálmán András Hormones in pregnancy and during fetal development Dr. Kovács Kálmán András Menstrual cycle. Contraception Dr. Kovács Kálmán András Menstrual cycle. Contraception Dr. Kovács Kálmán András Breast development. Hormones during lactation Dr. Vértes M Marietta Ontogeny of endocrine system Dr. Vértes M Marietta Hormones and bones Dr. Vértes M Marietta Endocrine system and aging Dr. Vértes M Marietta Discussion Dr. Vértes M Marietta Exams Dr. Vértes M Marietta Practices Seminars Exam topics/questions Written exam, multiple choice questions from lectures Participants Dr. Kovács Kálmán András (KOKFAFO.PTE), Dr. Vértes M Marietta (VEMMAAP.PTE) 137 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-AEM SELL YOURSELF! - PRESENTATION TECHNIQUES IN HEALTHCARE DR. JÓZSEF SZENTPÉTERI, honorary professor Medical Faculty (Medical School) Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 16 lectures + 8 practices + 0 seminars = total of 24 hours Course headcount limitations (min.-max.): 5 – 100 Prerequisites: no prerequisites Topic Improving students’ presentation skills. The aim of the course: theoretical and practical development of students’ verbal, non-verbal and visual presentation abilities. The course provides aids through following key aspects for effective communication: - Structure of presentation - Dynamics of presentation - Basic presentation techniques - Methods of effective persuasion - Audience survey - Questions, handling objections - Verbal content - Non-verbal communication / body language - Raising awareness, maintaining the feedback rating - The use of visual aids - Slideshow planning and preparation - Guidelines for charts, graphics preparation Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Text of up to five-minute presentation should be sent via e-mail to the lecturer by the half of the course (by the end of the calendar day right before the 13th lecture). Topic is chosen by the student and can be about anything. The topic should be the same as the exam at the end of the course. This topic can not be changed, but can be altered substantively by the day before the exam. If the presentation is not received by the instructor by e-mail to the above date (specified later), the course can not be continued, grade can not be obtained. Making up for missed classes There is no possibility to substitute a missing course. Catalog proving the presence should be filled and signed at each lecture. Course cannot be continued after missing 25% of the lectures. Reading material - Obligatory literature Literature is not compulsory, but all books in recommended literature list (see below) contain very useful information to provide a more effective implementation of the objectives of the course. - Literature developed by the Department Course material will be available in Microsoft PowerPoint (.ppt) format after course registration. - Notes See „Recommended literature” - Recommended literature Stephen R. Covey: The 7 Habits of Highly Effective People, Simon & Schuster UK Ltd., 1999 Carmine Gallo: The presentation secrets of Steve Jobs, McGraw-Hill, 2010 Edward T. Hall: The Hidden Dimension. Anchor Books, Doubleday, New York, 1966 Barbara Pease & Allan Pease: The Definitive Book of Body Language, Bantam Books, New York, 2006 Garr Reynolds: The Naked Presenter: Delivering Powerful Presentations With or Without Slides (Voices That Matter), New Riders Publishing, 2010. 138 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 What makes presentation effective? Preparing the audience. Promotional opportunities. The first 30 seconds. The humor, as a rhetorical device. The methodology of exercise. Timeout and compression. Dr. Szentpéteri József The structure of the presentation. Historical overview, classification. The fundamental rules of the structure of public speaking: rule of 3, rule of 5, rule of 7 and the 10-minute rule. Dr. Szentpéteri József Basic techniques of the performance (understandable language, understandable volume, awareness-raising dynamism, open communication, free talk) Dr. Szentpéteri József Effective communication and aids: avoidance of foreign words, simple sentences, intense words, rhetorical pause, stimulate debate, questioning; Metaphors, similes, dressing of numbers, repeating Dr. Szentpéteri József The basic techniques of persuasion. The audience survey, keeping it under control. Dr. Szentpéteri József Packaging the content. Questions, handling objections. Tools for arousing attention. Dr. Szentpéteri József Nonverbal tools of the presenter I: Appearance. Stage presence. Movement in the available space. Dr. Szentpéteri József Nonverbal tools of the presenter II: the face, hands gestures, posture, and their interpretation. Dr. Szentpéteri József Proper assessment of the audience reaction based on their non-verbal signals. Proper responses. Dr. Szentpéteri József Using visual aids I: How PSE (Picture Superiority Effect) can help to increase the effectiveness of the presentation? Dr. Szentpéteri József Using visual aids I.: The design of the slide show, preparation. Dr. Szentpéteri József Using visual aids III: Composition guidelines. Acquisition of images, correct and lawful use. Using animations. Dr. Szentpéteri József Using visual aids IV: flipchart, whiteboard, using laser pointers. Charts, guidelines for the preparation of graphics. Dr. Szentpéteri József Using visual aids V: Guidelines for the duration of each slide. The use of visual material, correct chronology. Dr. Szentpéteri József Using visual aids VI: videos, music and pictorial material. Overview of different presentation platforms (PowerPoint, Keynote, Prezi) Dr. Szentpéteri József Preparation methods: Text writing, design, technology, the specific room regarding with the expected audience. Dr. Szentpéteri József Practices 1 2 3 4 5 6 7 8 Tools to raise awareness I The first 30 seconds in different genres of performing arts. Tools to raise awareness II The use of enhancement in different genres of performing arts Application of effective volume, articulation and facial gestures. Nonverbal gestures supporting effective communication. Recognizing audience’s nonverbal signals. Performance analysis I Advertisements Performance Analysis II TED lectures Performance Analysis III Steve Jobs Seminars 139 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Exam topics/questions All students will present in front of the instructor and fellow students for up to 5 minutes duration. Everyone is free to choose their own topic. Both the instructor and the audience evaluating the presentation on pre-built scorecards up to 3 minutes duration. Evaluation sheet contains general and topic-specific questions. General questions are practically certain criteria, which should be evaluated from 1 to 10, where rate „1” is the worst and „10” is the best. General issues are as follows: 1. Welcoming audience 2. Link building and maintaining relationship with the audience 3. Arousing the interest (the first 30 seconds). In other words, has the presenter attracted your attention so much, that you would follow the complete presentation? (Themes, raising questions, humor, etc.). 4. Was the presentation interesting enough, that you want to know more about the topic? 5. The verbal performance of the speaker (Speech, volume, avoiding foreign words, etc.). 6. Nonverbal performance of the speaker (clothing, gestures, „theatrical” behavior) 7. Using Technical Aids - if any (did they fit and whether they helped the understanding). 8. Use of visual aids - if any (did they fit and whether they helped the understanding). 9. Overall, how would you rate the show? The subject-specific issues are not public; they will be completed by the instructor based on the submitted text and will be available on the day of the exam only. Participants Dr. Szentpéteri József (SZJGACT.PTE) 140 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-ANH BORDERLINE ANATOMY DR. DÓRA REGLŐDI, professor Department of Anatomy Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours Course headcount limitations (min.-max.): 5 – 150 Prerequisites: OAA-AA1 completed Topic The course offers insight into other aspects of anatomy, such as artistic aspects, historical background of anatomy. The lectures will also concentrate on the basic anatomical information, which are required for other non-medical jobs (trainer, physiotherapist, veterinarian). Students also gain insight into other anatomy teaching systems. Conditions for acceptance of the semester Mid-term exams Making up for missed classes It is not possible to catch up the lectures Reading material - Obligatory literature - Literature developed by the Department http://an-server.pote.hu - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Anatomy and history - history of dissection and anatomy teaching Dr. Reglődi Dóra Anatomy and art Dr. Reglődi Dóra Bone collections, anatomy museums, body parts of famous people Dr. Reglődi Dóra Anatomy and anthropology Dr. Márk László Anatomy and bodybuilding Dr. Reglődi Dóra Rembrandt: The Anatomy Lesson of Dr. Nicolaes Tulp - dissection of an anatomy painting Dr. Reglődi Dóra Anatomy teaching at a Caribbean university Dr. Farkas József Anatomy of body torturing, body modifications and circus shows Dr. Reglődi Dóra Anatomy teaching at other medical schools Dr. Tamás Andrea Anatomy of body massage Dr. Fülöp Balázs Dániel High-tech in anatomy Dr. Farkas József Closing lecture, test Dr. Reglődi Dóra Practices Seminars Exam topics/questions Participants 141 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-ASE PRESENTATION OF CASE REPORTS IN ENGLISH DR. VILMOS WARTA, assistant professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 3 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 100 Prerequisites: no prerequisites Topic The course intends to prepare participants to compose, understand and give biomedical case report presentations in English. Conditions for acceptance of the semester Participation in practicles is obligatory. Absences exceeding 15% but below 25% of the total number of contact hours can be excused by the group tutor. In case absences exceed 25% of the total number of contact hours the course must be regarded as uncompleted. Mid-term exams Making up for missed classes To be discussed with the course tutor in each individual case. Reading material - Obligatory literature - Literature developed by the Department Warta Vilmos: Writing Up Medical Case Reports, exe-learning, 2013 - Notes Warta Vilmos: Writing Up Medical Case Reports, 1st edition, 2013 - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction Dr. Warta Vilmos Introduction Dr. Warta Vilmos Communicative purpose and structure of case reports Dr. Warta Vilmos Communicative purpose and structure of case reports Dr. Warta Vilmos Verbal tenses in case reports Dr. Warta Vilmos Verbal tenses in case reports Dr. Warta Vilmos Impersonalisation Dr. Warta Vilmos Impersonalisation Dr. Warta Vilmos Modality and politeness strategies Dr. Warta Vilmos Modality and politeness strategies Dr. Warta Vilmos Lexis and terminology Dr. Warta Vilmos Lexis and terminology Dr. Warta Vilmos Presentation techniques Dr. Warta Vilmos Presentation techniques Dr. Warta Vilmos 142 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Presentation of case report 1 Dr. Warta Vilmos Presentation of case report 1 Dr. Warta Vilmos Presentation of case report 2 Dr. Warta Vilmos Presentation of case report 2 Dr. Warta Vilmos Presentation of case report 3 Dr. Warta Vilmos Presentation of case report 3 Dr. Warta Vilmos Presentation of case report 4 Dr. Warta Vilmos Presentation of case report 4 Dr. Warta Vilmos Presentation of case report 5 Dr. Warta Vilmos Presentation of case report 5 Dr. Warta Vilmos Consolidation Dr. Warta Vilmos Consolidation Dr. Warta Vilmos Course evaluation Dr. Warta Vilmos Course evaluation Dr. Warta Vilmos Practices Seminars Exam topics/questions 1) one PowerPoint presentation in English 2) one essay Participants 143 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-BUS BIOTECHNOLOGY FROM A BUSINESS PERSPECTIVE DR. JUDIT PONGRÁCZ, professor Department of Pharmaceutical Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 150 Prerequisites: no prerequisites Topic Interested in biotechnology but have no idea what it is? „Biotechnology from a Business Perspective” is designed to provide an overview of this relatively young industry. This new course introduces the scientific background behind biotechnology with a focus on the business aspects of the sector. Conditions for acceptance of the semester According to the Code of Studies and Examinations Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes www.medbiotech.com - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction to biotechnology: basic terms, definitions, historical overview Introduction to biotechnology: basic terms, definitions, historical overview Red (medical), green (agricultural) and white (industrial-environmental) biotech; examples Red (medical), green (agricultural) and white (industrial-environmental) biotech; examples Medical biotechnology: global and local results - Gene therapy and stem cell therapy - Cloning and transgenic animals - Molecular diagnostics, personalized medicine - Tissue engineering Medical biotechnology: global and local results - Gene therapy and stem cell therapy - Cloning and transgenic animals - Molecular diagnostics, personalized medicine - Tissue engineering Green biotechnology: potentials and results; Genetically Modified Organisms Green biotechnology: potentials and results; Genetically Modified Organisms Intellectual Property protection, technology transfer Financing of biotech, Venture Capital, Initial Public Offering Business models Spin-off, spin-out companies, other special characteristics of the industry Biotech vs. Big Pharma Case studies - Genentech, Amgen (USA) - Solvo, Cyclolab (Hungarian) Exam topics/questions www.medbiotech.com 144 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Participants Dr. Bognár Rita (BOREAA.K.JPTE), Dr. Pongrácz Judit (POJOAA-P.PTE), Kovácsné Kósa Judit (SOKDAB.F.JPTE) 145 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EBK FOOD SAFETY AND CRISIS SITUATIONS DR. TÍMEA VARJAS, assistant professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 4 – 30 Prerequisites: no prerequisites Topic Although food legislation and legal background is strict in EU some food safety crises and emergencies occur we can hear just a few word in the media about. This course „pulls the veil” of the background, causes and concealed information of food safety crises. Topics are about the most interesting and important information of these situations. Conditions for acceptance of the semester Absences should not exceed 15% of lectures and practicals (2x45 min). Otherwise signature of grade book is denied. Examination: written test Mid-term exams Exam: test after the last lecture. Re-take exam in the exam period. Making up for missed classes Based on individual consideration Reading material - Obligatory literature - Literature developed by the Department PPT-presentations (CooSpace) - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Introduction, European and Hungarian food safety regulation I Raposa László Bence Introduction, European and Hungarian food safety regulation II Raposa László Bence Cases and concealed facts I. (Historical overview) Raposa László Bence Cases and concealed facts II. (Historical overview) Raposa László Bence Crisis management and communication I Raposa László Bence Crisis management and communication II Raposa László Bence Cases and concealed facts III Raposa László Bence Cases and concealed facts IV Raposa László Bence Food industry „tricks”: Changes which the layman does not realize I Raposa László Bence Food industry „tricks”: Changes which the layman does not realize II Raposa László Bence Actual food safety crisis I Raposa László Bence Actual food safety crisis II Raposa László Bence 146 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Summary Raposa László Bence Exam Raposa László Bence Practices Seminars Exam topics/questions Coospace Participants 147 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EFA ETHNOPHARMACOBOTANY DR. NÓRA PAPP, assistant professor Department of Pharmacognosy Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 4 – 20 Prerequisites: no prerequisites Topic Course objective and role of the curriculum: Several written sources are available on the ethnobotanical usage and pharmaceutical history of medicinal plants from the ancient times. The course presents a summary about ethnobotanical data focusing on folk therapeutical methods and values of the Mediterranean area, Transylvania, countries of Europe, Asia, America and Africa completed by the scientific activity and curriculum vitae of ethnobotanists and researchers in this topic. Students receive an approach about the rules and regularity of the special folk terminology, about practice, folk customs and symbols in consideration of medicinal plants. Beside the method of an ethnobotanical collection the present state, position and necessity of these surveys are discussed during the course. Conditions for acceptance of the semester Criteria of acceptance of the semester: Satisfactory fulfilment of 2 written tests based on the lectures. Absences: according to the Code of Studies and Examinations of the Medical School. Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department http://aok.pte.hu/en/egyseg/oktatasianyagok/1640 - Notes - Recommended literature Recommended literature: Cunninham A. B.: Applied Ethnobotany. People, Wild Plant Use and Conservation, Earthscan, London, 2002 Ellen, Davi E., Hatfield, G.: Medicinal Plants in Folk Tradition an Ethnobotany of Britain and Ireland, Timber Press, Portland, Cambridge, 2004 Lise Manniche: The Ancient Egyptian Herbal, The British Museum Press, London, 1989 Martin G. J.: Ethnobotany. A Methods Manual, Earthscan, London, 2007 Minnis P. E.: Ethnobotany. A Reader, University of Oklahoma Press, U.S.A., 2000 Moerman, Daniel E.: Native American Ethnobotany, Timber Press, Portland, London, 2010 Paye, Gabriell DeBear: Cultural Uses of Plants, The New York Botanical Garden Press, Bronx, New York, 2000 Lectures 1 2 3 4 5 6 7 8 Ethnopharmacological data of the ancient times (Egypt, Mesopotamia). Dr. Papp Nóra Ethnopharmacological data of the ancient times (Egypt, Mesopotamia). Dr. Papp Nóra Ethnobotanical studies of the Native Indian populations of North, South and Central America (Cuba, Mexico). Dr. Papp Nóra Ethnobotanical studies of the Native Indian populations of North, South and Central America (Cuba, Mexico). Dr. Papp Nóra Ethnopharmacology of the ancient cultures of Iran, China, India, Tibet, Japan. Dr. Papp Nóra Ethnopharmacology of the ancient cultures of Iran, China, India, Tibet, Japan. Dr. Papp Nóra Ethnopharmacology of the countries of Africa. The Mediterranean regions (Greece, Spain, Portugal, Italy). Dr. Papp Nóra Ethnopharmacology of the countries of Africa. The Mediterranean regions (Greece, Spain, Portugal, Italy). Dr. Papp Nóra 148 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Ethnopharmacological data from the Middle Ages: therapy and medicinal plants in the gardens of the monasteries. Dr. Papp Nóra Ethnopharmacological data from the Middle Ages: therapy and medicinal plants in the gardens of the monasteries. Dr. Papp Nóra Transylvanian ethnobotanical values. Dr. Papp Nóra Transylvanian ethnobotanical values. Dr. Papp Nóra Written test I. Dr. Papp Nóra Written test I. Dr. Papp Nóra Ancient medico-botanical and herbal books and written sources with the morphological and therapeutical description of medicinal plants. Dr. Papp Nóra Ancient medico-botanical and herbal books and written sources with the morphological and therapeutical description of medicinal plants. Dr. Papp Nóra Scientific activity and curriculum vitae of ethnobotanists. Dr. Papp Nóra Scientific activity and curriculum vitae of ethnobotanists. Dr. Papp Nóra Methodologies and possibilities of the ethnobotanical collections. Dr. Papp Nóra Methodologies and possibilities of the ethnobotanical collections. Dr. Papp Nóra Interactive lecture: analysis and elaboration of scientific articles published in international journals and books based on knowledge and view of the previous lectures. Dr. Papp Nóra Interactive lecture: analysis and elaboration of scientific articles published in international journals and books based on knowledge and view of the previous lectures. Dr. Papp Nóra Traditional and folk terminology in the plant names. Dr. Papp Nóra Traditional and folk terminology in the plant names. Dr. Papp Nóra Medicinal plants in the folk customs, traditions as symbols. Dr. Papp Nóra Medicinal plants in the folk customs, traditions as symbols. Dr. Papp Nóra Written test II. Dr. Papp Nóra Written test II. Dr. Papp Nóra Practices Seminars Exam topics/questions Participants 149 the the the the UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-ETA HUMAN NUTRITION AND DIETETICS DR. ZSUZSANNA VÉRTES, associate professor Department of Physiology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 3 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 40 Prerequisites: OAA-MB2 completed Topic Medical students may find that this course will help them to coordinate their knowledge of the biological, physiological and clinical aspects of human nutrition. The lectures will include the following topics: Physiology of nutrition, general description of the foods most commonly eaten by man. Diet and physiological status (pregnancy, lactation, childhood, old age, exercise, sport and athletics). Clinical nutrition. The course will be divided into 5 parts: Part I gives an account of the physiology of nutrition Part II gives a general description of the foods most commonly eaten by man Part III describes those diseases that are known to be primarily due to faulty nutrition Part IV deals with the role of defective diets in contributing to the onset of general diseases which are not primarily nutritional in origin Part V deals briefly with the modifications necessary in normal diets to meet special circumstances of pregnancy, lactation, childhood, athletic training. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Small presentations Making up for missed classes As above Reading material - Obligatory literature - Literature developed by the Department Lecture notes - Notes - Recommended literature Garrow James: Human Nutrition and Dietetics Lectures 1 2 3 4 5 6 7 8 Energy metabolism Dr. Vértes Zsuzsanna Energy balance Dr. Vértes Zsuzsanna Digestion, absorption Dr. Vértes Zsuzsanna Digestion, absorption Dr. Vértes Zsuzsanna Carbohydrates Dr. Vértes Zsuzsanna Carbohydrates Dr. Vértes Zsuzsanna Fats Dr. Vértes Zsuzsanna Fats Dr. Vértes Zsuzsanna 150 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Protein Dr. Vértes Zsuzsanna Protein Dr. Vértes Zsuzsanna Vitamins Dr. Vértes Zsuzsanna Vitamins Dr. Vértes Zsuzsanna Minerals Dr. Vértes Zsuzsanna Minerals Dr. Vértes Zsuzsanna Water and body fluids Dr. Vértes Zsuzsanna Alcohol Dr. Vértes Zsuzsanna Nutrition during pregnancy and lactation Dr. Vértes Zsuzsanna Nutrition for growth and development Dr. Vértes Zsuzsanna Nutrition and physical fitness Dr. Vértes Zsuzsanna Nutrition and physical fitness Dr. Vértes Zsuzsanna Nutrition and weight management Dr. Vértes Zsuzsanna Eating disorders Dr. Vértes Zsuzsanna Nutrition and diabetes mellitus Dr. Vértes Zsuzsanna Nutrition and osteoporosis Dr. Vértes Zsuzsanna Overweight and obesity Dr. Vértes Zsuzsanna Overweight and obesity Dr. Vértes Zsuzsanna Exam Dr. Vértes Zsuzsanna Exam Dr. Vértes Zsuzsanna Practices Seminars Exam topics/questions Written exam Participants 151 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-FEA BASICS OF INFECTIOUS DISEASE EPIDEMIOLOGY DR. ISTVÁN KISS, professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 8 lectures + 3 practices + 3 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 15 Prerequisites: OAA-AED completed Topic However the morbidity and mortality caused by infectious diseases has significantly declined in the developed countries in the last century due to the effective prevention methods, their complete elimination is not possible, infectious diseases are still part of our everyday life. The spread of infectious diseases could be controlled by timely identification, proper investigation and by targeted interventions. Aim of the course is to present the special characteristics of infectious diseases, and of infectious disease epidemiology; basics and functioning of surveillance systems, the basics and steps of an outbreak investigation, and epidemiological methods used during the investigation. Conditions for acceptance of the semester The participation in the lectures, seminars, practises is obligatory (a catalogue should be signed), a maximum of 3x45 min absence is acceptable, above the signature will be rejected. Mid-term exams Further requirement is the successful completion of the written test at the end of the course. Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Heymann (ed.): Control of Communicable Diseases Manual M’ikanatha, Lynfield, Van Beneden, de Valk (eds.): Infectious Disease Surveillance Lectures 1 2 3 4 5 6 7 8 Special characteristics of infectious diseases Dr. Prantner Ida Basics of infectious disease epidemiology I Dr. Prantner Ida Basics of infectious disease epidemiology II Dr. Prantner Ida Methods used in infectious disease epidemiology Dr. Prantner Ida Basic principles of surveillance Dr. Prantner Ida Infectious disease surveillance Dr. Prantner Ida Basics and steps of outbreak investigation I Dr. Prantner Ida Basics and steps of outbreak investigation II Dr. Prantner Ida Practices 1 2 3 Use of epidemiological knowledge in practice I (definitions, surveillance data interpretation, analysis) Use of epidemiological knowledge in practice II (Data collection, analysis, graphical interpretations) Use of epidemiological knowledge in practice III (analytic studies) 152 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars 1 2 3 Investigation of a food-borne outbreak I Investigation of a food-borne outbreak II Investigation of a food-borne outbreak III Exam topics/questions Participants Dr. Prantner Ida (PRIFAAO.PTE) 153 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-FIT PHYTOTHERAPY DR. GYÖRGYI HORVÁTH, associate professor Department of Pharmacognosy Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 100 Prerequisites: OAA-ORK completed + OAA-MB2 completed Topic This course, similarly to the course of Szeged University, would like to provide knowledge about medicinal plants and their products used in the medical practice. Today many people purchase medicinal plants and herbal products to prevent or cure diseases. Therefore specialists (physicians and pharmacists) should become acquainted with medicinal plants and drugs that are used in pharmacotherapy (especially in phytotherapy) both in Hungary and abroad. During the interactive lectures, we would like to introduce the most important medicinal plants and their drugs which are characterized according to their active compounds, usage, dosage, interactions with other drugs and side-effects. Moreover, we highlight the results of preclinical experiments and/or human studies of the most important medicinal plants. We will show the official Herbal Monographs prepared by HMPC (Committee on Herbal Medicinal Products) and accepted by the European Medicines Agency (EMEA). A European Union herbal monograph comprises the scientific opinion of the HMPC on safety and efficacy data concerning a herbal substance and its preparations intended for medicinal use. The HMPC evaluates scientifically all available information including non-clinical and clinical data but also documented long-standing use and experience in the European Union. Because the medicinal use of different herbal products containing algae or mushrooms are highly popular, we would like to characterize and evaluate critically these products, as well. The aim of the phytotherapy course is to show the most important medicinal plants, their products and their use in the medical practice, to highlight the possible side-effects and interactions, which may occur during their application. We want to call students’ attention to the presence of adulterated herbal product being on the markets and on the internet. We hope that medical students having up-to-date knowledge about medicinal plants and their well-established use in the therapy can give appropriate advice to laypersons, who use a lot of herbal medicines, sometimes with or without medical supervision. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Satisfactory fulfillment of 1 written test based on the lectures. Students will write this test on 14th week. In case of failure written test, we guarantee two other possibilities. Making up for missed classes There is no possibility to make up for the missed lecture. Reading material - Obligatory literature - Literature developed by the Department - Farkas Á., Horváth Gy., Molnár P.: Pharmacognosy 1. Digital learning material (TÁMOP-4.1.2.A/1-11/1-2011-0016 project), 2014. - Horváth Gy., Molnár P., Bencsik T.: Pharmacognosy 2. Digital learning material (TÁMOP-4.1.2.A/1-11/1-2011-0016 project), 2014. - PowerPoint presentations based on the lectures. - Notes - Recommended literature - ESCOP Monographs. The Scientific Foundation for Herbal Medicinal Products. 2nd edition. Thieme, Exeter – Stuttgart – New York, 2003 - Williamson E., Driver S., Baxter K. (eds.): Stockley’s Herbal Medicines Interactions. Pharmaceutical Press, London, 2009. - Evans W.C.: Trease and Evans Pharmacognosy. Saunders, London-New York, 2000 - Aronson J.K. (ed.): Meyler’s Side Effects of Herbal Medicines. Elsevier, Amsterdam-Oxford-Tokyo, 2009 - Barnes J., Anderson L.A., Phillipson J.D.: Herbal Medicines. 2nd edition. Pharmaceutical Press, London-Chicago, 2002 154 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Definition of phytotherapy and its scope. Scientific and English name of medicinal plants and drugs. Different levels of the evaluation of herbal products: from in vitro experiments to human studies. Dr. Bencsik Tímea Natural substances in pharmaceutical research. Categories of herbal products: (traditional) herbal medicine, herbal tea and dietary supplement. Dr. Horváth Györgyi Ethnobotany and ethnomedicine. Non-clinical and clinical data and documented long-standing use of medicinal plants. Dr. Papp Nóra Immunmodulant medicinal plants. Medicinal role of mushrooms in the phytotherapy. Dr. Bencsik Tímea Medicinal value of algae and their metabolites in the phytotherapy. Dr. Horváth Györgyi Nutrition and phytotherapy in case of chronic diseases. Supportive role of phytotherapy in the treatment of cancer. Dr. Kőszegi Tamás Antal Medicinal plants in the treatment of respiratory diseases. Dr. Horváth Györgyi Medicinal plants in the treatment of cardiovascular diseases. Dr. Horváth Györgyi Medicinal plants in the treatment of gastrointestinal tract diseases. Dr. Bencsik Tímea Medicinal plants in the treatment of urogenital diseases. Dr. Papp Nóra Sedative and anxiolytic medicinal plants. Dr. Horváth Györgyi Medicinal plants in the treatment of locomotor disorders. Dr. Papp Nóra Medicine-medicinal plant-food interactions. Dr. Horváth Györgyi Written test. Dr. Horváth Györgyi Practices Seminars Exam topics/questions Topics of the written test: 1. Definition of phytotherapy and its scope. Definition of herbal drugs. 2. Scientific and English name of medicinal plants and drugs. 3. Natural substances in pharmaceutical research and in therapy. 4. Categories of herbal products: (traditional) herbal medicine, herbal tea, dietary supplements. 5. Ethnobotany. 6. Therapeutical use of medicinal plants based on tradition and/or clinical evidences. 7. Different levels of the evaluation of herbal products: from in vitro experiments to human studies. 8. Medicinal use of mushrooms in the phytotherapy. 9. Medicinal use of algae and their metabolites in the phytotherapy. 10. Medicine-medicinal plant-food interaction. 11. Medicinal value of plants in cancer therapy. 12. Medicinal plants in the treatment of respiratory diseases. 13. Medicinal plants in the treatment of cardiovascular diseases. 14. Medicinal plants in the treatment of gastrointestinal tract diseases. 15. Medicinal plants in the treatment of urogenital diseases. 16. Sedative and anxiolytic medicinal plants. 17. Medicinal plants in the treatment of locomotor disorders. Participants 155 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-GMS GENETICALLY MODIFIED ORGANISMS AND OUR HEALTH DR. ZOLTÁN GYÖNGYI, research associate professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 3 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAA-MB2 completed Topic The application of genetically modified organisms (GMOs) gains more and more ground in food industry. Over the direct health effect, they have an impact on human economy and health modifying natural environment. The topic provokes social debate, in which, in lack of information, delusions also appear. The goal of the education is that students receive impartial knowledge of the role of GMOs in our life and their beneficial or possible harmful impact on our health. During the education students receive a knowledge of molecular background of production of GMOs, their role in agriculture, the appeared cases and possible health risks, their occurrence in foodstuffs, medical applications, tests, regulations, authorization, economical and social impacts. Conditions for acceptance of the semester Attendance on lectures with maximum two absences. Mid-term exams Making up for missed classes Consultation with good cause. Reading material - Obligatory literature - Literature developed by the Department Lecture slides on Coospace - Notes - Recommended literature Morgan, Sally: Superfoods: Genetic Modification of Foods (Science at the Edge), Heinemann, 2003 ISBN 1-4034-4123-5. Lectures 1 2 3 4 5 6 7 8 9 10 11 The appearance of genetically modified organisms (GMOs) Dr. Gyöngyi Zoltán Role of GMOs in agriculture Dr. Gyöngyi Zoltán Basics of genetically modification I Dr. Gyöngyi Zoltán Basics of genetically modification II Dr. Gyöngyi Zoltán Possible harmful effect of GMOs to health Dr. Gyöngyi Zoltán Background of deaths caused by GM food Dr. Gyöngyi Zoltán Prevention of GMO induced health hazard Dr. Gyöngyi Zoltán Genetically modification in medicine Dr. Gyöngyi Zoltán GMOs in food I Dr. Gyöngyi Zoltán GMOs in food II Dr. Gyöngyi Zoltán Authorization of GMOs Dr. Gyöngyi Zoltán 156 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 Regulation of application Dr. Gyöngyi Zoltán Impact of GMOs on nature environment and eco farms Dr. Gyöngyi Zoltán Effect of GM business on economy, social debates and the flow of information Dr. Gyöngyi Zoltán Practices Seminars Exam topics/questions 1. Reasons, why GMOs are created 2. The role of GMOs in the agriculture 3. Impact of GMOs on natural environment and organic farms 4. Molecular basics of genetically modifications 5. Application of genetic modification in the medicine 6. The cause of deaths because of GM food 7. Possible harmful effect of GMOs to health 8. Prevention of harmful effect of GMOs 9. Occurrence of GMOs in foodstuffs, food tests 10. Authorization of GMOs, social debate, flow of information 11. Health impacts of glyphosate 12. Health impacts of Bt toxin Participants 157 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-GP1 WRITING AND MANAGING SUCCESSFUL GRANT PROPOSALS 1 DR. JUDIT PONGRÁCZ, professor Department of Pharmaceutical Biotechnology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 14 lectures + 14 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: no prerequisites Topic Introduction to the writing and managing successful Grant Proposals. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes 1. Robert Porter: Writing Good Grant Proposals, The Journal of Research Administration, Volume XXXVIII, Number 2, 2007, 37-43 pp. 2. Henso, Kenneth T.: Grant Writing in Higher Education: A Step-by-step Guide, 2004 3. Nancy Burke Smith, E. Gabriel Works: The Complete Book of Grant Writing: Learn to Write Grants Like a Professional, Sourcebooks, Inc., Nov 30, 2006 4. Joseph W. Weiss, Robert K. Wysocki: 5-Phase Project Management: A Practical Planning & Implementation Guide, AddisonWesley, 1992 5. R. R. Rattihalli, D. J. Field: How to Write a Good Research Grant Proposal, Paediatrics and Child Health, Volume 22, Issue 2, February 2012, Pages 57-60 6. K. C. Chung, M. J. Shauver: Fundamental Principles of Writing a Successful Grant, Proposal JHS Vol 33A, April 2008 7. G.H. Koppelman, J.W. Holloway: Successful Grant Writing, Paediatric Respiratory Reviews 13 (2012) 63-66 8. M.P. Haggard: Writing Research Proposals, Current Obstetrics and Gynaecology 1996, 6, 119 - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 Introduction to the structure of different call systems I. (call systems in the European Union) Dr. Bognár Rita Introduction to the structure of different call systems I. (call systems in the USA) Dr. Bognár Rita Main steps of project planning (project idea, SWOT analysis, Problem Tree Analysis, objective tree analysis Dr. Bognár Rita Main steps of project planning (Logical Framework Approach-logframe matrix, Responsible Activity Matrix) Dr. Bognár Rita Human relation backgrounds of a project proposal (specify interested groups-target groups, stakeholders analysis, project team member building) Dr. Bognár Rita Project network plan (CPM, MPM, PERT) Dr. Bognár Rita Implementation Schedule - Work Plan (project background, project summary, project milestones, project time planning- Ganttdiagram, indicators) Dr. Bognár Rita Communication plan (communication tools, target groups, communication channels) Dr. Bognár Rita Type of project risks, risk management Dr. Bognár Rita 158 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 10 11 12 13 14 Budget planning (staff cost, direct cost (fixed assets, intangible assets, other cost), indirect cost) Dr. Bognár Rita Contracting, partnership agreement, amendments Dr. Bognár Rita Project evaluation (kick off meeting, meetings, quality management, financial management, controlling) Dr. Bognár Rita Amendments during the implementation period of the project I. Dr. Bognár Rita Project reports (progress report, final reports, maintenance report) Dr. Bognár Rita Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Research and identify potential funding sources in the EU(S) Research and identify potential funding sources in the USA(S) Team work – case study: Main steps of project planning (project idea, SWOT analysis, Problem Tree Analysis, objective tree analysis Team work – case study: Main steps of project planning (Logical Framework Approach-logframe matrix, Responsible Activity Matrix) Team work – case study: Human relation backgrounds of a project proposal (specify interested groups-target groups, stakeholders analysis, select and introduce project team members) Team work – case study: Project network plan (CPM, MPM, PERT) Team work – case study: Implementation Schedule - Work Plan (project background, project summary, project milestones, project time planning- Gantt-diagram, indicators) Team work – case study: Communication plan (communication tools, target groups, communication channels) Team work – case study: Type of project risks, risk management Team work – case study: Budget planning (staff cost, direct cost (fixed assets, intangible assets, other cost), indirect cost) Team work – case study: Contracting, partnership agreement, amendments Team work – case study: Project evaluation (kick off meeting, meetings, quality management, financial management, controlling) Team work – case study: Amendments during the implementation period of the project I. Team work – case study: Project reports (progress report, final reports, maintenance report) Seminars Exam topics/questions www.medbiotech.hu CooSpace Participants Dr. Bognár Rita (BOREAA.K.JPTE) 159 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-HAK THE CHEMISTRY OF DEATH DR. LÁSZLÓ MÁRK, associate professor Department of Biochemistry and Medical Chemistry Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 100 Prerequisites: no prerequisites Topic Death is not an unaltering state, and far from being an inert mass, the dead body is, under normal circumstances, subject to many complex and, often enough, only partly investigated changes arising from intrinsic as well as extrinsic causes which bring about quite substantial chemical and morphological alterations of the tissues. Under natural conditions an initially intact body commences to decompose immediately after death, the aim of this course is the integration of these decomposition processes into medical and chemical, biochemical sciences. Topics: - Introduction to toxicology - Enzymatic reactions - The last minutes of life - Postmortem changes in general - Postmortem enzymal changes - Postmortem non-enzymal chemical changes - Postmortem chemical changes (short term) - Postmortem chemical changes (long term) - Special chemical processes, mummification - Pathological observations - Traumatic changes - Forensic and paleoanthropological methods - Dating methods Conditions for acceptance of the semester Written exam. Max. absences: 20%. Mid-term exams None. Making up for missed classes Not possible. Reading material - Obligatory literature - Literature developed by the Department Lecture slides and notes. - Notes - Recommended literature Evans: The Chemistry of Death, 1963 Stein: Physical Anthropology, 1976 Lectures 1 2 3 4 Introduction. Basics of toxicology Dr. Márk László Introduction to biochemistry and enzymatic alterations. Dr. Márk László Chemical processes of the last few minutes of the life. Dr. Márk László Chemical processes of the last few minutes of the life. Dr. Márk László 160 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 5 6 7 8 9 10 11 12 13 14 General postmortem changes. Dr. Márk László General postmortem changes. Dr. Márk László Short term postmortem changes. Dr. Márk László Short term postmortem changes. Dr. Márk László Chemical alterations of the first hours. Dr. Márk László Chemical alterations of the first hours. Dr. Márk László Decomposition processes. Dr. Márk László Decomposition processes. Dr. Márk László Special chemical modifications, mummification. Dr. Márk László Pathological and traumatic investigations. Dr. Márk László Practices Seminars Exam topics/questions Introduction to toxicology Enzymatic reactions The last minutes of life Postmortem changes in general Postmortem enzymal changes Postmortem non-enzymal chemical changes Postmortem chemical changes (short term) Postmortem chemical changes (long term) Special chemical processes, mummification Pathological observations Traumatic changes Forensic and paleoanthropological methods Dating methods Participants 161 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-JNF HISTORY OF EPIDEMICS AND THE GREAT DISCOVERIES DR. ISTVÁN KISS, professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 12 lectures + 2 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: no prerequisites Topic Epidemics of infectious diseases have always played a role in human history. The morbidity and mortality of infectious diseases greatly shaped the demography, politics, and culture. The causative agents of diseases had long been a mystery for which numerous theories were proposed. Discovery of pathogens meant the beginning of a new era of epidemiology and the possibility of the effective fight against infectious diseases. Although the significance of communicable diseases in developed countries is less and less important today, the history of the epidemiological discoveries is still an interesting field of medical science. This special field of medicine play also today a very important role in preventive medicine. The students can get an inside view of cardinal discoveries and the history of great epidemics. Conditions for acceptance of the semester Participation in lectures and practicals is obligatory which is registered. Absences should not exceed 15% (2x45 min). Otherwise signature of grade book is denied. Mid-term exams Written test. Making up for missed classes There are no make-up classes. Reading material - Obligatory literature - Literature developed by the Department Educational material uploaded on CooSpace. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 History of epidemiology. Importance of infectious diseases in the past centuries and in our time I Dr. Németh Katalin History of epidemiology. Importance of infectious diseases in the past centuries and in our time II Dr. Németh Katalin Great epidemics in the history I (Plague, Smallpox, Typhus) Dr. Németh Katalin Great epidemics in the history II (Plague, Smallpox, Typhus) Dr. Németh Katalin Great epidemics in the history III (Childhood Diseases) Dr. Németh Katalin Great epidemics in the history IV (Childhood Diseases) Dr. Németh Katalin Great epidemics in the history V (Tropical illnesses, Influenza) Dr. Németh Katalin Great epidemics in the history VI (Tropical illnesses, Influenza) Dr. Németh Katalin Discovery of pathogens I Dr. Németh Katalin Discovery of pathogens II Dr. Németh Katalin 162 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 Discovery of vaccines I Dr. Németh Katalin Discovery of vaccines II Dr. Németh Katalin Practices 1 2 Bioterrorism and biological warfare I Bioterrorism and biological warfare II Seminars Exam topics/questions CooSpace Participants Dr. Németh Katalin (NEKFABO.PTE) 163 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-KAM CLINICAL ANATOMY DR. TIBOR HOLLÓSY, assistant professor Department of Anatomy Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 20 Prerequisites: OAA-AA1 completed + OAA-SF1 completed + OAA-AA2 parallel Topic The aim of the course is to show how anatomical knowledge is used in everyday clinical practice. The presenters of the course are mainly clinicians who use their experience gained during their anatomy education, in the everyday practice. During the lessons the students will experience diagnostical and therapeutical methods (e.g. physical, ultrasound and dentistry examinations, operation of hernias) which need certain knowledge of anatomy and show its practical approach in use. Conditions for acceptance of the semester 1.) participation at least in 75% of seminars 2.) successful written test. Mid-term exams Making up for missed classes On the judgement of the tutor. Reading material - Obligatory literature - Literature developed by the Department http://an-server.pote.hu Color Atlas of Human Anatomy, Thieme - Notes - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Practice in MediSkillsLab I Knee pain - clinical- and pathoanatomy of the knee. What does the laryngoscope see? Long in the tooth! A guided tour of the thorax with eyes, ears and hands. Anatomical aspects of thoracal X-ray examination. Anatomy in the ER! Vascular and transplant surgery. The abdominal wall and beyond. Practice in MediSkillsLab II Appendectomy - surgery of the dead-end route of the colon. Clinical anatomy of the female pelvis - rocking tranquillity of the hammock. Interactive ultrasound examination in the Department of Radiology. Test. Exam topics/questions Written test on the last seminar. Participants Dr. Dányádi Bese (DABNAAO.PTE), Dr. Faluhelyi Nándor (FANFAAO.PTE), Dr. Fülöp Balázs Dániel (FUBOAA-O.PTE), Dr. Józsa Gergő (JOGIAAO.PTE), Dr. Kardos Dániel József (KADPABO.PTE), Dr. Koppán Miklós Endre (KOMHADE.PTE), Dr. Németh Adrienne (NEASAAP.PTE), Dr. Sándor Balázs Attila (SABFAA.T.JPTE), Dr. Schlégl Ádám Tibor (SCAPAAO.PTE), Dr. Szakály Péter (SZPMAAO.PTE) 164 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MC1 METHODS IN MOLECULAR CELL BIOLOGY I DR. MARIANNA PAP, associate professor Department of Medical Biology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 10 lectures + 18 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 1 – 20 Prerequisites: OAA-MB2 completed Topic The main objective of the course to improve theoretical knowledge and practical skills of students. The course covers the most important technics used in molecular cell biology. On the small-group discussions theoretical background of molecular cell biology methods are described and discussed. On the practicals students perform basic experiments used in Department of Medical Biology. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes Individually discussed Reading material - Obligatory literature - Literature developed by the Department Hand-outs prepared by the Medical Biology Department - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 Tissue culture methods (cell culturing, harvesting, counting, freezing procedures) Dr. Pap Marianna Tissue culture methods (cell culturing, harvesting, counting, freezing procedures) Dr. Pap Marianna Vectors used in molecular cell biology, types of transformation, stabile and transient transfection Dr. Pap Marianna Vectors used in molecular cell biology, types of transformation, stabile and transient transfection Dr. Pap Marianna Analysis of DNA I. (DNA isolation, types of gelelectrophoresis) Dr. Pap Marianna Analysis of DNA I. (DNA isolation, types of gelelectrophoresis) Dr. Pap Marianna Analysis of DNA II. (Enzimatical manipulation of DNA) Dr. Pap Marianna Analysis of DNA II. (Enzimatical manipulation of DNA) Dr. Pap Marianna Analysis of DNA III. (Microchip analysis, in vitro mutagenesis, analysis of DNA-protein interactions) Dr. Pap Marianna Analysis of DNA III. (Microchip analysis, in vitro mutagenesis, analysis of DNA-protein interactions) Dr. Pap Marianna Practices 1 2 3 4 5 6 Tissue culture methods - demonstration (cell culturing, harvesting, counting, freezing procedures) Tissue culture methods - demonstration (cell culturing, harvesting, counting, freezing procedures) Tissue culture methods - demonstration (cell culturing, harvesting, counting, freezing procedures) Tissue culture methods (plate cells) Tissue culture methods (harvesting cells) Tissue culture methods (harvesting cells) 165 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 7 8 9 10 11 12 13 14 15 16 17 18 Tissue culture methods (freezing cells) Tissue culture methods (freezing cells) Tissue culture methods (counting cells) Tissue culture methods (counting cells) Tissue culture methods (counting cells) Tissue culture methods (counting cells) Transient transfection of tissue culture cells using a green fluorescent protein expressing plasmid (counting and plate cells) Transient transfection of tissue culture cells using a green fluorescent protein expressing plasmid (counting and plate cells) Transient transfection of tissue culture cells using a green fluorescent protein expressing plasmid (transfection) Transient transfection of tissue culture cells using a green fluorescent protein expressing plasmid (transfection) Transient transfection of tissue culture cells using a green fluorescent protein expressing plasmid (fixation, staining of nuclei) Transient transfection of tissue culture cells using a green fluorescent protein expressing plasmid (check the expression by confocal laser scanning microscopy) Seminars Exam topics/questions Participants Kiss Katalin (KIKFABO.PTE), Németh Mária (NEMGAAT.PTE), Varga Judit (VAJGACT.PTE) 166 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MGE MOLECULAR GERONTOLOGY DR. KRISZTIÁN KVELL, associate professor Department of Pharmaceutical Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 200 Prerequisites: OAA-MB1 completed + OAA-EL1 parallel Topic The curriculum covers physiological aspects of ageing and the molecular background of the ageing process, at cell, intracellular signaling and nucleic acid level. It highlights the potential molecular intervention possibilities to slow down the ageing process and decrease development of age related diseases. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes www.medbiotech.com - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Basic Knowledge in Gerontology Dr. Kvell Krisztián Aging Theories Dr. Kvell Krisztián Mitochondrial Aging Dr. Kvell Krisztián Aging and Gene Expression Dr. Kvell Krisztián Genetic Background of Longevity Dr. Kvell Krisztián Alterations of the Genome due to Aging, Senescence and Cancer Dr. Kvell Krisztián Cellular Effects of Acute and Chronic Stress Dr. Kvell Krisztián Metabolism and Longevity I Dr. Kvell Krisztián Metabolism and Longevity II Dr. Kvell Krisztián Senescence-related Intracellular Pathologies Dr. Kvell Krisztián Senescence-related Intracellular Pathologies Dr. Kvell Krisztián Molecular Mechanisms of Interventions Dr. Kvell Krisztián Invited Lecturer I Dr. Kvell Krisztián Invited Lecturer II Dr. Kvell Krisztián 167 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions CooSpace www.medbiotech.com Participants 168 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MNE MOLECULAR NEUROENDOCRINOLOGY DR. ISTVÁN MIKLÓS ÁBRAHÁM, associate professor Department of Physiology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 25 Prerequisites: OAA-MB2 completed Topic A hallagatók betekintést kapnak a modern neuroendokrinológiai szemléletbe, sok kísérleti példával és klinikai relevanciával. Megismerkedhetnek azokkal a legújabb kutatási adatokkal, amelyek a hormonok molekuláris hatásait leírják a központi idegrendszerbe. Ezen felül áttekintést kapnak a molekuláris neuroendokrinológia legmodernebb eszköztáráról. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Egy on-line számonkérés az erre a célre kialakított on-line web felületen, a kurzus utolsó előadása után, amely felölei az egész kurzus anyagát. Making up for missed classes Reading material - Obligatory literature Élettan tankönyvek - Literature developed by the Department Előadás ábrák és filmek. - Notes Hallgatói saját rövid feljegyzések. - Recommended literature Kandel: Principles of Neuronal Science, 5th edition, 2012 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Functional anatomy and the role of the hypothalamus and pituitary gland I Dr. Ábrahám István Miklós Functional anatomy and the role of the hypothalamus and pituitary gland II Dr. Ábrahám István Miklós Major intracellular signalling pathways I Dr. Ábrahám István Miklós Major intracellular signalling pathways II Dr. Ábrahám István Miklós Methods in molecular neurendocrinology I Dr. Ábrahám István Miklós Methods in molecular neurendocrinology II Dr. Ábrahám István Miklós The neuroendocrine regulation of stress response I Dr. Ábrahám István Miklós The neuroendocrine regulation of stress response II Dr. Ábrahám István Miklós Action of glucocorticoids on neurons- role in neurodegenerative processes I Dr. Ábrahám István Miklós Action of glucocorticoids on neurons- role in neurodegenerative processes II Dr. Ábrahám István Miklós The neuronal regulation of fertility I Dr. Ábrahám István Miklós The neuronal regulation of fertility II Dr. Ábrahám István Miklós 169 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Genomic and non-genomic effect of estrogen on neurons I Dr. Ábrahám István Miklós Genomic effect of estrogen on neurons II Dr. Ábrahám István Miklós Practices Seminars Exam topics/questions Tesztkérdések az előadások anyagából. Participants 170 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MTS ALTERED STATES OF CONSCIOUSNESS IN THE SOMATIC MEDICINE DR. ISTVÁN TIRINGER, assistant professor Department of Behavioural Sciences Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 3 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 15 Prerequisites: no prerequisites Topic The aim of the course is to provide insight for the students about the possible types and causes of altered states of consciousness in the somatic medicine. The newest genetic and imaging studies bring medicine nearer to a deeper level understanding of consciousness, while the experiences gained from the medical practice gives us useful support in recognizing that the impact of illnesses, fears and hospital surroundings make the patients more sensitive to the statements of doctors. Utilizing these knowledge can provide optimalization for the doctor-patient communication, thus creating more understanding and a better healing surrounding, which can lead to a greater satisfaction and faster rehabilitation between patients. Conditions for acceptance of the semester Maximum of 25 % absence allowed. Active work and one presentation from the given topics is obligatory. Written exam at the end of the course. Mid-term exams Making up for missed classes Should be discussed with the course tutor in each individual case. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Varga K. (ed.): Beyond the Words: Communication and Suggestion in Medical Practice, ELTE Eötvös Press, Budapest, 2011 James, U.: Clinical Hypnosis Textbook: A Guide for Practical Intervention, Radcliffe Publishing Ltd, Oxford, 2010 Kroger, W. S.: Clinical and Experimental Hypnosis in Medicine, Dentistry and Psychology, Lippincott Williams & Wilkins, Philadelphia, PA, 2008 Cardena, E., Winkelman, M. (eds.): Altering Consciousness: Multidisciplinary Perspectives. Volume 1: History, Culture, and the Humanities. Volume 2: Biological and Psychological Perspectives, Praeger Publishers, Santa Barbara, CA, 2012 Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 Altered states of consciousness, types and definitions Altered states of consciousness, types and definitions Hypnosis and suggestions Hypnosis and suggestions Placebo and nocebo Placebo and nocebo Anxiety, fears and coping strategies Anxiety, fears and coping strategies Illness awareness and illness processing Illness awareness and illness processing Communitation, types and definitions Communitation, types and definitions The psychology of pain The psychology of pain Non-pharmacological pain therapy Non-pharmacological pain therapy Dissociation, definitions and adaptive forms Dissociation, definitions and adaptive forms 171 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 19 20 21 22 23 24 25 26 27 28 States of consciousness under general anesthesia States of consciousness under general anesthesia Altered consciousness while suffering loss Altered consciousness while suffering loss Rapport building situations in the medical praxis Rapport building situations in the medical praxis Involvement of the healer: empathy and burnout Involvement of the healer: empathy and burnout Summary Summary Exam topics/questions Participants Trixler Dániel (TRDNABO.PTE) 172 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-N37 ANATOMICAL TERMINOLOGY 2 GABRIELLA HÁBEL, language teacher Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: no prerequisites Topic Anatomical Terminology concerning the internal organs. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes To be discussed with the instructor. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature University script Donáth, Tibor: Lexicon Anatomiae. Anatomical Dictionary, Semmelweis, Bp. 1999 Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Terminology pertaining to the pharynx, maxilla, mandible, oral cavity and teeth (Hábel Gabriella) Terminology pertaining to the pharynx, maxilla, mandible, oral cavity and teeth (Hábel Gabriella) Anatomical terms relating to the tongue and muscles of the tongue (Hábel Gabriella) Anatomical terms relating to the tongue and muscles of the tongue (Hábel Gabriella) Respiratory tract I. Anatomical terminology of the nose, paranasal sinuses and larynx (Hábel Gabriella) Respiratory tract I. Anatomical terminology of the nose, paranasal sinuses and larynx (Hábel Gabriella) Respiratory tract II. Terminology of the lungs (Hábel Gabriella) Respiratory tract II. Terminology of the lungs (Hábel Gabriella) Anatomical terminology pertaining to the heart and cardiovascular system (Hábel Gabriella) Anatomical terminology pertaining to the heart and cardiovascular system (Hábel Gabriella) Terminology of the digestive system, stomach and intestines (Hábel Gabriella) Terminology of the digestive system, stomach and intestines (Hábel Gabriella) Terminology of the peritoneum, liver, gallbladder and pancreas (Hábel Gabriella) Terminology of the peritoneum, liver, gallbladder and pancreas (Hábel Gabriella) Test paper (Hábel Gabriella) Test paper (Hábel Gabriella) Terminology pertaining to the urinary system (Hábel Gabriella) Terminology pertaining to the urinary system (Hábel Gabriella) Anatomical terminology pertaining to the male reproductive system (Hábel Gabriella) Anatomical terminology pertaining to the male reproductive system (Hábel Gabriella) Anatomical terminology pertaining to the female reproductive system (Hábel Gabriella) Anatomical terminology pertaining to the female reproductive system (Hábel Gabriella) Repetition concerning the terminology of internal organs (Hábel Gabriella) Repetition concerning the terminology of internal organs (Hábel Gabriella) 173 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 25 26 27 28 Repetition. Anatomical terms pertaining to bones, muscles, joints, ligaments (Hábel Gabriella) Repetition. Anatomical terms pertaining to bones, muscles, joints, ligaments (Hábel Gabriella) Test paper (Hábel Gabriella) Test paper (Hábel Gabriella) Exam topics/questions Participants Hábel Gabriella (HAGTAAP.PTE) 174 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-STH ADVANCED HISTOLOGY DR. ANDREA TAMÁS, associate professor Department of Anatomy Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours Course headcount limitations (min.-max.): 5– Prerequisites: OAA-SF1 completed Topic The course offers broader knowledge from histology, additional to the obligatory course, with the assistance of experienced teachers and clinicians of the Medical Faculty. The aim of the course: To get a deeper understanding of the morphology, ultrastructure and function of different structures of the organs, to get insight into methodological processes. Conditions for acceptance of the semester The acceptance of the semester: The semester score (1 to 5) will be based on the quality of final written exam. To receive the credit, at least score 2 (satisfactory) should be received and the student must participate in more than 75 % of the practices. Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department http://an-server.pote.hu - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Microscopic slides in 3 dimensional aspect Dr. Horváth Judit Life or death? Apoptosis. Dr. Reglődi Dóra Histology of oral cavity from clinical aspect Dr. Sándor Balázs Attila Histology of lymphoid system. Dr. Gaszner Balázs Structure of the heart: morphological characteristics of cardiac valves, myocardium and conducting system Dr. Halmosi Róbert Respiratory system Dr. Tamás Andrea Characteristics of the gastrointestinal tract. Three-dimensional organization of the intestinal villi. Dr. Tamás Andrea Structures of the liver. Dr. Kériné Dr. Józsa Rita Structures of the urinary system Dr. Tamás Andrea The reproductive cycle: maturation of follicles. What determines the selection of the follicle during maturation Dr. Kovács Magdolna In vitro fertilization Dr. Török Attila Consultation Dr. Tamás Andrea Practices Seminars Exam topics/questions Written test, questions are based on the materials of the lectures 175 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Participants 176 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-TD1 STUDENT PROJECT RESEARCH 1 DR. PÉTER BALOGH, associate professor Undergraduate Research Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 3 Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours Course headcount limitations (min.-max.): 1 – 300 Prerequisites: no prerequisites Topic The aim of this subject is to nurture and promote the activity of students sufficiently motivated to perform biomedical project research. The students may progressively enrol to four parts in four separate semesters, for the total credit value of 8. For acknowledging the 3rd and 4th (elective) parts, the student must train research student novice(s). The subject’s administrator is the actual Chairman of the Students’ Research Society (SRS) of the Faculty of Medicine. Conditions for acceptance of the semester To enrol this course a registered SRS membership is mandatory. Acknowledging the course requires (a) either first-author presentation of work at a Students’ conference (UP or elsewhere) or Dean’s assay, or presentation at any professional conference relevant to the research field, or (b) progress report on the work performed or demonstrating expertise at the methodology employed before the Tutor and the Chairman of SRS. Grades will be accorded corresponding to the criteria set out in the Rules and Regulations of SRS. For detailed requirements please read the following document: http://aok.pte.hu/run/download2.php?idf=11791&nyelv=eng Mid-term exams Making up for missed classes Not applicable. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Not applicable Lectures Practices 1-24 Research Seminars Exam topics/questions Not applicable Participants Dr. Balogh Péter (BAPOAGP.PTE) 177 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-TEK TECHNOLOGICAL DISASTERS AND THEIR IMPACT ON HEALTH DR. TÍMEA VARJAS, assistant professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 3 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 30 Prerequisites: no prerequisites Topic Technological disasters took part in the ever-growing environmental pollution. These exposures mean an acute and also a chronic exposure affecting our health. The aim of the course is to highlight the most memorable disasters from the 20th century. Risk of the toxic agents, the underlying failures that lead to disasters, acute and chronic health effects and prevention strategies are also discussed. Conditions for acceptance of the semester Absences should not exceed 15% of lectures and practicals (2x45 min). Otherwise signature of grade book is denied. Examination: written test Mid-term exams Exam: test after the last lecture. Re-take exam in the exam period. Making up for missed classes Based on individual consideration Reading material - Obligatory literature - Literature developed by the Department PPT-presentations (CooSpace) - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Introduction - Classification of technological disasters Dr. Szabó István Toxicological aspects of disasters Dr. Szabó István Toxicological aspects of disasters Dr. Szabó István Air pollution - The Great London Smog Dr. Szabó István Air pollution - Smog Dr. Szabó István Toxicological aspects of mineral oil Dr. Szabó István Oil disasters Dr. Szabó István Chemical industrial disasters Dr. Szabó István Chemical industrial disasters Dr. Szabó István Agricultural disasters Dr. Szabó István Disasters in Hungary (River Tisza, Nagytétény, Red Sludge) Dr. Szabó István Chernobyl nuclear power plant disaster Dr. Szabó István 178 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Chernobyl nuclear power plant disaster Dr. Szabó István Nuclear disasters Dr. Szabó István Practices Seminars Exam topics/questions Coospace Participants 179 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-TMB MOLECULAR BIOLOGY OF TUMORS DR. EDINA PANDUR, assistant professor Department of Pharmaceutical Biology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 4 – 30 Prerequisites: OAA-MB1 completed + OAA-MB2 completed Topic During the course we will discuss the molecular mechanisms of tumor development. We will deal with characteristic features of tumor cells, and cancers. The function of influencing factors, risk factors, causes, the underlying molecular mechanisms, e.g. mutations, the role of oncogenes and tumor-suppressor genes, DNA repair, epigenetics and the role of immune system will be discussed in detail. We will emphasize the function of cell signaling pathways and the failure of apoptosis in tumorigenesis. We will speak about the molecular mechanisms of invasion and metastasis of tumors, the genes and proteins which have a crucial role in these processes. The participants will get an insight into the molecular diagnosis, genetic aberrations, and molecular alterations of human cancers. We will discuss the possibilities for cancer therapies, the new approaches such as gene therapy and immunotherapy. Conditions for acceptance of the semester Max. 1 absence Mid-term exams Making up for missed classes Personal consultation Reading material - Obligatory literature - Literature developed by the Department Educational materials will be uploaded to Coospace - Notes - Recommended literature Lauren Pecorino: Molecular Biology of Cancer Wolfgang Arthur Schulz: Molecular Biology of Human Cancers Lectures 1 2 3 4 5 6 7 8 Introduction to cancers: classification and characterization of cancers, causes of cancer, properties of cancer cells, principles of therapies, targets of therapies Dr. Pandur Edina Introduction to cancers: classification and characterization of cancers, causes of cancer, properties of cancer cells, principles of therapies, targets of therapies Dr. Pandur Edina Tumor genetics: mutations, carcinogenic agents, inheritance, tumor genes, defects in DNA repair and predispositions to cancer, cell protection mechanisms Dudás Réka Tumor genetics: mutations, carcinogenic agents, inheritance, tumor genes, defects in DNA repair and predispositions to cancer, cell protection mechanisms Dudás Réka Tumor epigenetics: mechanisms of epigenetic inheritance, imprinting, DNA methylation, epigenetics of cell differentiation and tissue homeostasis Poór Viktor Soma Tumor epigenetics: mechanisms of epigenetic inheritance, imprinting, DNA methylation, epigenetics of cell differentiation and tissue homeostasis Poór Viktor Soma Oncogenes and tumor-suppressor genes Dr. Pandur Edina Oncogenes and tumor-suppressor genes Dr. Pandur Edina 180 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 The cell cycle, apoptosis and senescence: checkpoints, therapeutic targets and inhibitors, molecular mechanisms of apoptosis, replicative senescence and its disturbances in human cancers Dr. Sipos Katalin The cell cycle, apoptosis and senescence: checkpoints, therapeutic targets and inhibitors, molecular mechanisms of apoptosis, replicative senescence and its disturbances in human cancers Dr. Sipos Katalin Signaling pathways in tumors: MAPK, PI3K, TP53 network, NFkappaB, TGFbeta, STAT signaling Dr. Pandur Edina Signaling pathways in tumors: MAPK, PI3K, TP53 network, NFkappaB, TGFbeta, STAT signaling Dr. Pandur Edina Invasion and metastasis: genes and proteins involved in cell-to-cell, cell-matrix adhesion, in extracellular matrix remodeling during tumor invasion; angiogenesis. Varga Edit Invasion and metastasis: genes and proteins involved in cell-to-cell, cell-matrix adhesion, in extracellular matrix remodeling during tumor invasion; angiogenesis. Varga Edit The role of immune system in tumors: inflammation, infections, cancer vaccines, inhibition of the immune system Rácz Evelin The role of immune system in tumors: inflammation, infections, cancer vaccines, inhibition of the immune system Rácz Evelin Stem cells and cancer: Wnt signaling, Hh signaling, differentiation therapy Dr. Pandur Edina Stem cells and cancer: Wnt signaling, Hh signaling, differentiation therapy Dr. Pandur Edina Cancer prevention: nutrients, energy metabolism of tumors, hormones and gene interactions Dudás Réka Cancer prevention: nutrients, energy metabolism of tumors, hormones and gene interactions Dudás Réka Diagnosis of tumors: molecular diagnosis, molecular detection and classification Rácz Evelin Diagnosis of tumors: molecular diagnosis, molecular detection and classification Rácz Evelin Human cancers I: common properties, genetic aberrations, molecular alterations, histology and etiology of cancers Dr. Tóth Dénes Human cancers I: common properties, genetic aberrations, molecular alterations, histology and etiology of cancers Dr. Tóth Dénes Human cancers II: common properties, genetic aberrations, molecular alterations, histology and etiology of cancers Dr. Tóth Dénes Human cancers II: common properties, genetic aberrations, molecular alterations, histology and etiology of cancers Dr. Tóth Dénes Drugs in cancer therapy: molecular mechanisms of cancer chemotherapy, targeted drug therapy, immunotherapy, gene therapy Dr. Poór Miklós Drugs in cancer therapy: molecular mechanisms of cancer chemotherapy, targeted drug therapy, immunotherapy, gene therapy Dr. Poór Miklós Practices Seminars Exam topics/questions Participants 181 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-TSA STATISTICAL ANALYSIS OF THESIS AND STUDENT RESEARCH PROJECTS DR. KORNÉLIA FARKAS-BORBÁS, assistant professor Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 3 Number of hours/semester: 7 lectures + 7 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 20 Prerequisites: no prerequisites Topic This course is for those students who are working on a student research plan or working on their thesis. They can process their own data and learn the theory of the applied statistical methods as well. Conditions for acceptance of the semester Problem solving, oral report Mid-term exams None Making up for missed classes Consultation Reading material - Obligatory literature - Literature developed by the Department Own database - Notes - Recommended literature Andrew F. Siegel: Statistics and Data Analysis. An introduction, John Wiley & Sons, 1988 Douglas G. Altman: Practical Statistics for Medical Research, Chapman & Hall, 1994 P. Armitage and G. Berry: Statistical Methods in Medical Research, Blackwell Science, 1994 Robert R. Sokal / F. James Rohlf: Biometry, W. H. Freeman and Company, New York, 1981 Lectures 1 2 3 4 5 6 7 Set the data and complete the database for statistical processing Borbásné Dr. Farkas Kornélia Select the right statistical methods Borbásné Dr. Farkas Kornélia Learn the theory of the selected methods Borbásné Dr. Farkas Kornélia Learn the theory of the selected methods Borbásné Dr. Farkas Kornélia Interpret the results Borbásné Dr. Farkas Kornélia Interpret the results Borbásné Dr. Farkas Kornélia Conclusions Borbásné Dr. Farkas Kornélia Practices 1 2 3 4 5 6 7 Set the data and complete the database for statistical processing Select the right statistical methods Learn the theory of the selected methods Learn the theory of the selected methods Interpret the results Interpret the results Conclusions 182 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Participants Borbásné Dr. Farkas Kornélia (FAKAAA.T.JPTE) 183 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-TSS MEDICAL APPLICATIONS OF MASS SPECTROMETRY DR. LÁSZLÓ MÁRK, associate professor Department of Biochemistry and Medical Chemistry Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 3 Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours Course headcount limitations (min.-max.): 3 – 100 Prerequisites: no prerequisites Topic In medical sciences, emphasis is increasingly placed on instrumental techniques and accurate, quantitative measurements. This course is give an overall review about the modern mass spectrometry and it shows the medical applications of the MS in the clinical and diagnostic practice. Topics: Introduction to MS. Ionsources, analizators, detectors. Separation techniques. Sample handling. Biomedical sampling. Bioinformatics. Proteomics, metabolomics and lipidomics. Biomarker discovery. Mass spectrometric imaging techniques. Conditions for acceptance of the semester Written exam. Max. absences: 20%. Mid-term exams None. Making up for missed classes Not possible. Reading material - Obligatory literature - Literature developed by the Department Lecture slides and notes. - Notes - Recommended literature Vékey et al: Medical Applications of Mass Spectrometry, 2008. Hoffman et al: Mass Spectrometry, 2007 Lectures 1 2 3 4 5 6 7 8 9 10 11 Introduction Dr. Márk László Basics of mass spectrometry Dr. Márk László Basics of mass spectrometry Dr. Márk László Ionization techniques Dr. Márk László Analizators Dr. Márk László Detectors, The mass spectrum Dr. Márk László Biomedical sampling Dr. Márk László Separation techniques, sample preparation Dr. Márk László Separation techniques, sample preparation Dr. Márk László Proteomics Dr. Márk László Proteomics Dr. Márk László 184 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 15 16 17 18 19 20 21 22 23 24 Metabolomics Dr. Márk László Metabolomics Dr. Márk László Mass spectrometry of endocrine system Dr. Márk László Mass spectrometry of endocrine system Dr. Márk László Biomarker discovery Dr. Márk László Biomarker discovery Dr. Márk László Lipidomics Dr. Márk László Lipidomics Dr. Márk László Proteomics of viruses and bacteria Dr. Márk László Proteomics of viruses and bacteria Dr. Márk László Molecular imaging by MS Dr. Márk László Exam Dr. Márk László Exam Dr. Márk László Practices Seminars Exam topics/questions Ionsources. Analizators. Detectors. Separation techniques. Sample handling. Biomedical sampling. Bioinformatics. Proteomics. Metabolomics Lipidomics. Biomarker discovery. Mass spectrometric imaging techniques. MS of endocrine system. Participants 185 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-2DA TWO-DIMENSIONAL ANATOMY - MODERN MEDICAL IMAGING TECHNIQUES DR. BALÁZS GASZNER, associate professor Department of Anatomy Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 60 Prerequisites: OAA-AA2 completed Topic Demonstration of thoracic, abdominal, pelvic and the intra-cranial anatomy by computer tomography (CT), magnetic resonance imaging (MRI), ultrasound and radioactive isotope imaging techniques. The applications of these iconographic techniques in internal medicine, obstetrics, gynecology, neurology, urology, and neurosurgery will be presented. The aim of the course is to demonstrate the high importance of anatomical knowledge in modern medicine, and call attention to contemporary imaging techniques in the clinical practice. Conditions for acceptance of the semester Writing two successful tests, and attendance at 75% of the lectures. Mid-term exams Making up for missed classes None. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Csillag András: Anatomy of the Living Human. Atlas of Medical Imaging, Köenemann, Köln, 1999. Han/Kim: Sectional Human Anatomy, Ilchokak: Seoul; Igaku - Shoin: New York-Tokyo, 1989 or later editions Weir, J. et al: Imaging Atlas of Human Anatomy, 4th ed., Mosby, Elsevier 2010. Mai, J.K., Assheuer, J., Paxinos, G.: Atlas of the Human Brain, Academic Press, 1997. Visible Human (Web), http://an-server.pte.hu Lectures 1 2 3 4 5 6 7 8 9 10 11 Topography of thoracic organs in horizontal, frontal and sagittal planes Dr. Gaszner Balázs Investigation of the moving heart and its valves by modern imaging techniques Dr. Habon Tamás Topography of abdominal organs in horizontal, frontal and sagittal planes Dr. Gaszner Balázs Diagnostic labyrinth of body cavities Dr. Battyáni István Internal organs and the skeleton as shown by radioactive isotope imaging Dr. Bódisné Dr. Zámbó Katalin Topography of pelvic organs in horizontal, frontal and sagittal planes Dr. Gaszner Balázs Imaging techniques in the urological practice Dr. Pytel Ákos Use of imaging techniques in obstetrics and gynecology. Dr. Farkas Bálint Anatomy of the brain in CT and MRI images Dr. Gaszner Balázs Angiography of the neck and head Dr. Gaszner Balázs The anatomy of pain as seen by magnetic resonance imaging (fMRI) Dr. Komoly Sámuel 186 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 In vivo neuroanatomical „dissection” of the human brain with the aid of MRI: functional morphology Dr. Schwarcz Attila Imaging of the central nerval system using techniques of nuclear medicine Dr. Bódisné Dr. Zámbó Katalin Modern imaging techniques in neurosurgery Dr. Fehér Máté Practices Seminars Exam topics/questions No exam questions available. Participants 187 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-BSK BIOINORGANIC CHEMISTRY DR. ATTILA AGÓCS, associate professor Department of Biochemistry and Medical Chemistry Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 40 Prerequisites: OAA-OM1 completed Topic The course deals with biological importance of elements (metals and nonmetals) in the living organisms discussing the effects of common toxic elements. Basic respect of studying the interaction of ions, molecules and biopolymers. It gives a basic knowledge and facilitates to understand certain chapters of medical biochemistry. Some previous knowledge of biochemistry (at least one semester) is highly recommended. Conditions for acceptance of the semester Successful written exam. Mid-term exams Making up for missed classes None. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature P. Gergely (ed.): Introduction to Bioinorganic Chemistry for Medical Students, latest edition, Univ. Med. School of Debrecen Wolfgang Kaim, Brigitte Schwederski: Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, latest edition, Wiley Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 Introduction to bioinorganic chemistry I Dr. Agócs Attila Introduction to bioinorganic chemistry II Dr. Agócs Attila Structure of biocomplex compounds Dr. Takátsy Anikó Chelates Dr. Takátsy Anikó Life essential elements Dr. Agócs Attila Evolution of inorganic chemicals Dr. Agócs Attila Evolution of organic chemicals Dr. Agócs Attila Uptake of metallic elements Dr. Takátsy Anikó Uptake of anions, molecules Dr. Takátsy Anikó Biological importance of alkali metals Dr. Berente Zoltán Biological importance of alkaline earth metals Dr. Berente Zoltán Bioinorganic chemistry of Fe-ions Dr. Berente Zoltán Bioinorganic chemistry of Cu-ions Dr. Berente Zoltán 188 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Bioinorganic chemistry of Zn-ion Dr. Berente Zoltán Bioinorganic chemistry of transition metals I Dr. Berente Zoltán Bioinorganic chemistry of transition metals II Dr. Berente Zoltán Bioinorganic chemistry of transition metals III Dr. Berente Zoltán Test Paper I. Dr. Agócs Attila Biological role of aluminium Dr. Agócs Attila Biological role of silicon Dr. Agócs Attila Function of nitrogen in biological systems Dr. Agócs Attila Function of phosphorus in biological systems Dr. Agócs Attila Dioxygen, oxygen free radicals I Dr. Agócs Attila Dioxygen, oxygen free radicals II Dr. Agócs Attila Boron, Selenium Dr. Agócs Attila Arsenic and other non-metallic elements Dr. Agócs Attila Biological functions of halogenes Dr. Agócs Attila Test Paper II Dr. Agócs Attila Practices Seminars Exam topics/questions Lecture slides will be uploaded to CooSpace. Participants 189 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-EAH PHYSIOLOGY OF THE ADAPTATION LIMITS OF THE HUMAN BODY DR. JÓZSEF LÁSZLÓ KÖRNYEI, associate professor Department of Physiology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 220 Prerequisites: OAA-EL1 completed Topic Following a short review of the relevant physiological regulatory mechanisms, this course focuses on the adaptation limits of the human body under extreme strain situations. The knowledge gained here gives assistance to students with the understanding of the physiological integrative collaboration of organ systems of the human body. Sessions embrace the physiological regulatory mechanisms of the body, the collaboration of different organ systems, while special emphasis is placed on the possible physiological limits and their origins in cases of: high altitudes, deep sea diving, high and low environmental temperatures, starvation and obesity, dehydration and heavy water/salt intake, physical exercise, movement or inactivity, effects of gravity, accelerations, kinetosis, weightlessness, then vision, hearing, intellectual work, attention, concentration, learning/memory, exhaustion, sleep withdrawal, psychological tensions and behavioral activity, usage of tools to overcome these limits. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams The two in-semester computer test programs can be downloaded from the CooSpace and, the result sheet (scoreboard) file .SCB (all catch-ups and corrections included) must be submitted before the announced deadline (appx. two weeks). Making up for missed classes Missed movies can be viewed once on discussed and agreed time schedule, the figures of the lectures are available on the CooSpace. Reading material - Obligatory literature Physiology textbooks - Literature developed by the Department Figures of the lectures, edited movies - Notes Short notes of the students - Recommended literature Physiology textbooks Lectures 1 2 3 4 5 6 7 8 Introduction, objectives of the course, topics and methods. Dr. Környei József László Forms of upward movements I, physiology of adaptation limits: Hiking. Dr. Környei József László Forms of upward movements II, Physiological problems during hiking, adaptation limits and their origins. Dr. Környei József László Forms of upward movements II, Physiological problems during hiking, adaptation limits and their origins. Dr. Környei József László Forms of upward movements III, Gravitational effects, accelerations and their monitoring, physiology of microgravity surroundings. Dr. Környei József László Forms of upward movements III, Gravitational effects, accelerations and their monitoring, physiology of microgravity surroundings. Dr. Környei József László Forms of underwater activity I, Physiology of the adaptation limits Dr. Környei József László Forms of underwater activity I, Physiology of the adaptation limits Dr. Környei József László 190 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Deep sea diving II, Physiology of the adaptation limits Dr. Környei József László Deep sea diving II, Physiology of the adaptation limits Dr. Környei József László Consultation Dr. Környei József László 1st in-semester report test. Dr. Környei József László Thermal strain situations I: Total body and local cold effects Dr. Környei József László Thermal strain situations I: Total body and local cold effects Dr. Környei József László Thermal strain situations II: Total body and local warm effects Dr. Környei József László Thermal strain situations II: Total body and local warm effects Dr. Környei József László Mechanical resistance of the human body: passive limits (accidental traumas) Dr. Környei József László Sport and military strain situations, physiological limits of muscular work. Dr. Környei József László Reaction time, coordination of movements, physiology of active limits. Dr. Környei József László Causes of accidents, the human factor. Dr. Környei József László Electric current and radioactivity limits. Dr. Környei József László Weather fronts, physiology of orientation Dr. Környei József László Physiological limits of sensory organs in humans, vision and hearing. Dr. Környei József László Fear and overcoming it, adrenalin need, effects of sleep withdrawal, upper limits of concentration. Dr. Környei József László Physiology of time shift problems, jet-lag. Dr. Környei József László Intellectual work, memory, will-power and survival skills. Dr. Környei József László Consultation Dr. Környei József László 2nd in-semester report test, defining progress grades Dr. Környei József László Practices Seminars Exam topics/questions Test questions based on the topics of the lectures. Participants 191 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-H4A MEDICAL HUNGARIAN 4A - BASICS OF MEDICAL COMMUNICATION DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OAE-H4B parallel + OAE-H3A completed Topic This course continues providing language and communicative functions in five more areas of medical history taking and is also meant to give opportunities for putting skills and knowledge into practice in preparation for the final exam. Conditions for acceptance of the semester Participation in class work is obligatory. In case absences exceed 25% of total class time, the course will be regarded as uncompleted. In the case of absences up to 25% of total class time, oral examination will have to be taken Mid-term exams Making up for missed classes Participation is obligatory. Reading material - Obligatory literature - Literature developed by the Department Mária Győrffy: English for Doctors, Idióma Bt. Pécs, 2001 - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Paediatrics Paediatrics Paediatrics Dermatology Dermatology Dermatology ENT ENT ENT Ophthalmology Ophthalmology Ophthalmology Dentistry Dentistry Consolidation Test 1 Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Test 2 Course evaluation 192 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Participants Dr. Hegedűs Anita (HEAAAA.B.JPTE), Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE), Dr. Warta Vilmos (WAVEAB.B.JPTE), Eklicsné Dr. Lepenye Katalin (EKLAXA.B.JPTE), Hamarné Sávay Judit (HASMAAO.PTE), Hild Gabriella (MAGAAD.B.JPTE), Horváth Lilla Anita (HOLFABP..PTE), Kurdiné Molnár Eszter (KUMPAAK.PTE), Lokodiné Szolcsányi Judit (LOSIAAB.PTE), Mészégetőné Halmos Éva (MEHHABE.PTE), Móriczné Győrffy Mária (MOGPAAP.PTE), Ronczykné Berta Anikó (BEAAAI.B.JPTE), Szántóné Csongor Alexandra (CSAAAA.B.JPTE), Váradi Katalin (VAKHAAE.PTE) 193 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-H4B MEDICAL HUNGARIAN 4B - MEDICAL COMMUNICATION IN PRACTICE DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OAE-H4A parallel + OAE-H3B completed Topic This course is meant to further develop listening comprehension and speaking skills in five areas of history taking and also to practicing the newly acquired skills in preparation for the final exam in Medical Hungarian. Conditions for acceptance of the semester Participation in class work is obligatory. In case absences exceed 25% of total class time, the course will be regarded as uncompleted. In the case of absences up to 25% of total class time, oral examination will have to be taken Mid-term exams Making up for missed classes Participation is obligatory. Reading material - Obligatory literature - Literature developed by the Department Mária Győrffy: English for Doctors, Idióma Bt. Pécs, 2001 - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Paediatrics - Listening comprehension and speaking skills Paediatrics - Listening comprehension and speaking skills Paediatrics - Listening comprehension and speaking skills Dermatology - Listening comprehension and speaking skills Dermatology - Listening comprehension and speaking skills Dermatology - Listening comprehension and speaking skills ENT - Listening comprehension and speaking skills ENT - Listening comprehension and speaking skills ENT - Listening comprehension and speaking skills Ophthalmology - Listening comprehension and speaking skills Ophthalmology - Listening comprehension and speaking skills Ophthalmology - Listening comprehension and speaking skills Dentistry - Listening comprehension and speaking skills Dentistry - Listening comprehension and speaking skills Consolidation Test 1 Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Preparation for the Final Exam in Medical Hungarian Test 2 Course evaluation 194 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Participants Dr. Hegedűs Anita (HEAAAA.B.JPTE), Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE), Dr. Warta Vilmos (WAVEAB.B.JPTE), Eklicsné Dr. Lepenye Katalin (EKLAXA.B.JPTE), Hamarné Sávay Judit (HASMAAO.PTE), Hild Gabriella (MAGAAD.B.JPTE), Horváth Lilla Anita (HOLFABP..PTE), Kurdiné Molnár Eszter (KUMPAAK.PTE), Lokodiné Szolcsányi Judit (LOSIAAB.PTE), Mészégetőné Halmos Éva (MEHHABE.PTE), Móriczné Győrffy Mária (MOGPAAP.PTE), Nagy Gabriella (NAGMAAO.PTE), Ronczykné Berta Anikó (BEAAAI.B.JPTE), Szántóné Csongor Alexandra (CSAAAA.B.JPTE), Váradi Katalin (VAKHAAE.PTE) 195 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-MPS MEDIZINISCHE PSYCHOLOGIE UND SOZIOLOGIE DR. TIRINGER, ISTVÁN, Assistent Institut für Verhaltensmedizin Lehrbeauftragte/r: 4 ECTS-Punkte ▪ SZN ▪ Elektives Modul ▪ SS ▪ Rekommandiert Semester: 4. Semesterwochenstunden: 28 Vorlesungen + 0 Übungen + 28 Seminare = Insgesamt 56 Zahl der Kursteilnehmer für Kurs: 5 - 200 Voraussetzungen: OAA-MB2 erfüllt Thematik Das Ziel des Faches ist die Ergänzung biomedizinischer Inhalte der anderen Grundlagenfächer mit einer psychosozialen Annäherung und als Integration eine komplexe biopsychosoziale Betrachtungsweise medizinischer Problemen. Dieses Modell ist die Grundlage späteren klinischen Fächern, wie z.B. der Psychosomatischen Medizin, der Psychiatrie, der Allgemeinen Medizin. Die Thematik des Faches orientiert sich an dem neuen Gegandstandskatalog für den schriftlichen Teil der ärztlichen Vorprüfung. Studenten/Studentinnen erhalten das notwendige Grundlagewissen über psychologische und soziologische Aspekte ärztlichen Handelns. Es werden Grundlagen zum Verständnis der psychosozialen Aspekte von Gesundheit und Krankheit vermittelt. Ein weiterer zentraler Bereich beschäftigt sich mit dem ärztlichen Handeln. Unsere praxisorientierten Seminaren fördern die Aneignung von im ärztlichen Alltag nützlichen und notwendigen Kompetenzen. Unser dritter Themenschwerpunkt ist das Grundwissen über Förderung und Erhaltung von Gesundheit, welcher eine präventive ärztliche Denkweise begründet. Voraussetzung zum Absolvieren des Semesters 1. Prüfung: Multiple Choice Test. Wiederholte Prüfung: mündlich Fehlzeiten: max. 15% des Gesamtstundenzahles Semesteranforderungen Möglichkeiten zur Nachholung der Fehlzeiten Registrierte Teilnahme im Seminar einer anderen Gruppe (nur ausnahmsweise). Materialien zum Aneignen des Lehrstoffes - Obligatorische Literatur Empfohlene Lehrbücher: - Faller, Hermann; Lang, Hermann: Medizinische Psychologie und Soziologie, 24.95 Euro, 3. vollständig neu bearb. Aufl., 2010 Springer, ISBN: 978-3-642-12583-6 - Siegrist, Johannes: Medizinische Soziologie, 10.95 Euro, 6. Aufl., Urban & Fischer, 2005 ISBN: 3-437-41232-9 zur Endklausurvorbereitung / zum Nachschlagen / zur Vertiefung: - Kasten & Sabel: Original-Prüfungsfragen mit Kommentar, GK-1 (Physikum), Medizinische Psychologie, Medizinische Soziologie, 29,95 Euro; 17. Aufl., Thieme, Stuttgart, 2011 ISBN-13: 9783131149275 - Buddeberg: Psychosoziale Medizin, Springer-Lehrbuch; Preis: 39.95 Euro, 3. aktuelle Aufl. 29,95 Euro; Springer, Berlin, 29,95 Euro; ISBN: 3-540-63955-1 - Brähler, E., Strauß, B.: Grundlagen der medizinischen Psychologie, Hogrefe, Göttingen, 2012. ISBN: 9783801705770 - Vom Institut veröffentlichter Lehrstoff CooSpace - Skript - Empfohlene Literatur Vorlesungen 1 2 3 4 5 6 1. Emotion. Motivation Dr. Tiringer István 1. Emotion. Motivation Dr. Tiringer István 2. Lernen, Gedächtnis, kognitive Faktoren des (Gesundheits-)Verhaltens. Dr. Tiringer István 2. Lernen, Gedächtnis, kognitive Faktoren des (Gesundheits-)Verhaltens. Dr. Tiringer István 3. Theorien der Persönlichkeit. Bezüge zur Krankheit und Gesundheit. Verhaltensgenetik Dr. Tiringer István 3. Theorien der Persönlichkeit. Bezüge zur Krankheit und Gesundheit. Verhaltensgenetik Dr. Tiringer István 196 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 4. Die wichtigsten Modelle zur Entwicklung der Persönlichkeit (Freud, Erikson, Piaget, Bindungsforschung). Dr. Birkás Béla 4. Sekundäre Sozialisation (Adoleszenz, mittleres Erwachsenalter, Senium). Soziodemographische und kulturelle Determinanten des Lebenslaufs. Dr. Tiringer István 5. Einführung in die medizinische Soziologie Faubl Nóra 5. Einführung in die medizinische Soziologie Faubl Nóra 6. Moderne Gesundheits- und Krankheitsmodelle: biopsychologische, psychodynamische und sozialpsychologische Modelle. Dr. Tiringer István 6. Moderne Gesundheits- und Krankheitsmodelle: biopsychologische, psychodynamische und sozialpsychologische Modelle. Dr. Tiringer István 7. Das biopsychosoziale Modell am Beispiel des psychosozialen Stress. Psychoneuroimmunologische Grundkenntnisse. Biologische Grundlagen des Verhaltens. Neurobiologie. Dr. Tiringer István 7. Das biopsychosoziale Modell am Beispiel des psychosozialen Stress. Psychoneuroimmunologische Grundkenntnisse. Biologische Grundlagen des Verhaltens. Neurobiologie. Dr. Tiringer István 8. Grundzüge der Kommunikation. Besonderheiten der Arzt-Patient Kommunikation. Dr. Tiringer István 8. Grundzüge der Kommunikation. Besonderheiten der Arzt-Patient Kommunikation. Dr. Tiringer István 9. Krankheitsbewältigung. Konzept der gesundheitsbezogenen Lebensqualität. Dr. Tiringer István 9. Krankheitsbewältigung. Konzept der gesundheitsbezogenen Lebensqualität. Dr. Tiringer István 10. Plazebo, Nozebo Dr. Tiringer István 10. Plazebo, Nozebo Dr. Tiringer István 11. Die wichtigsten Formen der Psychotherapie und ihre Entwicklung. Die Bedeutung der Krisenintervention im medizinischen Kontext. Dr. Tiringer István 11. Die wichtigsten Formen der Psychotherapie und ihre Entwicklung. Die Bedeutung der Krisenintervention im medizinischen Kontext. Dr. Tiringer István 12. Ostermontag Dr. Tiringer István 12. Ostermontag Dr. Tiringer István 13. Gesundheitserziehing und Gesundheitsförderung. Formen der Prävention Verhaltensänderung. Grundzüge der ärztlichen Rehabilitation. Dr. Tiringer István 13 Gesundheitserziehing und Gesundheitsförderung. Formen der Prävention Verhaltensänderung. Grundzüge der ärztlichen Rehabilitation. Dr. Tiringer István 14. Psychokardiologie Dr. Tiringer István 14. Psychokardiologie Dr. Tiringer István Praktika Seminare 1 2 3 4 Methodische Grundlagen: Beispiele aus konkreten Untersuchungen. Methodische Grundlagen: Beispiele aus konkreten Untersuchungen. Psychologische Messinstrumente in der medizinischen Psychologie. Psychologische Messinstrumente in der medizinischen Psychologie. 197 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Psychologische Teste: Intelligenzteste. Persönlichkeitsteste, projektive Verfahren Psychologische Teste: Intelligenzteste. Persönlichkeitsteste, projektive Verfahren Psychologie der Emotionen: Angst, Aggression. Psychologie der Emotionen: Angst, Aggression. Psychologie der Emotionen: Scham, Trauer. Psychologie der Emotionen: Scham, Trauer. Die ersten Lebensjahre des Kindes. Entwicklung der geschlechtlichen Identität. Geschlechterfragen in der Medizin. Die ersten Lebensjahre des Kindes. Entwicklung der geschlechtlichen Identität. Geschlechterfragen in der Medizin. Ärztliche Sozialisation. Ärztliche Ausbildung. Ärztliche Sozialisation. Ärztliche Ausbildung. Altruismus. Helfer-Syndrom. Burnout. Altruismus. Helfer-Syndrom. Burnout. Ärztliche Gesprächsituationen. Ärztliche Gesprächsituationen. Ärztliche Gesprächsführung (Kommunikationstraining). Ärztliche Gesprächsführung (Kommunikationstraining). Ärztliche Gesprächsführung (Kommunikationstraining). Ärztliche Gesprächsführung (Kommunikationstraining). Veränderung des Gesundheitsverhaltens. Motivationales Interview. Veränderung des Gesundheitsverhaltens. Motivationales Interview. Psychosoziale Interventionsprogramme in der Medizin. Psychosoziale Interventionsprogramme in der Medizin. Psychoonkologie Psychoonkologie Prüfungsfragen Vorlesungs-, und Seminar-Folien: Coospace Lehrer Dr. Birkás Béla (BIBGAAB.PTE), Dr. Tiringer István (TIIHAAE.PTE), Faubl Nóra (FANAAA.B.JPTE), Trixler Dániel (TRDNABO.PTE) 198 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-SEX SEXOLOGY DR. GÉZA HARTMANN, professor emeritus Department of Physiology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ both semesters semester ▪ recommended semester: 4 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 20 Prerequisites: OAA-EL1 completed + OAA-MB2 completed Topic Because a lot of doctors cannot give advice to patients having sexual problems, we try to give information to the medical students for recognition and therapy of sexual dysfunctions. The lectures discuss the history of human sexuality and sexual investigations, the physiology of the sexual response, the organic and psychological causes of sexual dysfunctions and variations (deviations), sexual problems in puberty and climacteric, contraception, the pornography and prostitution, etc. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Kaplan, H. S.: The Sexual Desire Disorders Kaplan, H. S.: The New Sex Therapy Hite, S.: Hite Report: Shere Hite - A Nationwide Study of Female Sexuality Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 History of sexual investigations Dr. Hartmann Géza History of human sexuality Dr. Hartmann Géza Sexual problems in puberty Dr. Bálint Írisz Boglárka Sexual problems in puberty Dr. Bálint Írisz Boglárka Contraception Dr. Garai János Contraception Dr. Garai János Stages of sexual reaction Dr. Hartmann Géza Desire disorders and their treatment Dr. Hartmann Géza Stage of excitement Dr. Hartmann Géza Stage of excitement Dr. Hartmann Géza Masturbation Dr. Hartmann Géza Disfunctions in excitement state in women, treatment. Dr. Hartmann Géza Mechanisms of erection Dr. Hartmann Géza 199 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Erectile dysfunction and treatment Dr. Hartmann Géza Surgical treatment of erectile dysfunction Dr. Hartmann Géza Surgical treatment of erectile dysfunction Dr. Hartmann Géza Premature ejaculation. Retarded ejaculation. Dr. Hartmann Géza Orgasm Dr. Hartmann Géza Orgastic dysfunction Dr. Hartmann Géza Treatment of orgastic dysfunctions Dr. Hartmann Géza Vaginismus. Dr. Hartmann Géza Sexual problems in older ages Dr. Hartmann Géza Sexual deviations Dr. Tényi Tamás Sexual deviations Dr. Tényi Tamás Forensic medicine and sexology Dr. Simon Gábor Forensic medicine and sexology Dr. Simon Gábor Pornography and prostitution Dr. Hartmann Géza Test Dr. Hartmann Géza Practices Seminars Exam topics/questions Test exam Participants 200 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-TIZ CENTRAL REGULATION OF FEEDING AND METABOLISM. NEW APPROACHES DR. ZOLTÁN KARÁDI, professor Department of Physiology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 2 – 25 Prerequisites: OAA-MB2 completed + OAA-OK2 completed + OAA-AA2 parallel Topic The high incidence and costs of eating and metabolic disorders make it indispensable to experimentally test new theoretical considerations, and to employ their conclusive results in basically new clinical protocols. Students at early stage of their studies are, thus, encouraged to familiarize with new theoretical aspects and experimental findings. Neural and humoral mechanisms in the central feeding control and metabolic regulation. Body weight control in health and disease. Peripheral and central taste information processing; gustation in the central regulation of food and fluid intake. Obesity, diabetes mellitus and the metabolic syndrome: New interpretations. Conditions for acceptance of the semester According to general regulations Mid-term exams Making up for missed classes Individually discussed Reading material - Obligatory literature Guyton & Hall: Textbook of Medical Physiology, Saunders - Literature developed by the Department - Notes - Recommended literature Williams and Pickup: Handbook of Diabetes, Blackwell Doty: Handbook of Olfaction and Gustation, Marcel Dekker Lectures 1 2 3 4 5 6 7 8 9 10 Physiological significance of food and fluid intake, and metabolism. Dr. Karádi Zoltán Homeostasis, motivation. Dr. Karádi Zoltán Neuronal and humoral factors in the central regulation of homeostatic functions: brain centers, neurotransmitter pathways, neuropeptides. I Dr. Karádi Zoltán Neuronal and humoral factors in the central regulation of homeostatic functions: brain centers, neurotransmitter pathways, neuropeptides. II Dr. Karádi Zoltán Neuronal and humoral factors in the central regulation of homeostatic functions: brain centers, neurotransmitter pathways, neuropeptides. III Dr. Karádi Zoltán Exogenous chemosensory modalities. Physiologic roles of gustation. Dr. Karádi Zoltán Central taste pathways, „labeled lines”, neurons. Dr. Karádi Zoltán Taste preference, taste aversion, palatability, flavour. Dr. Karádi Zoltán The glucose-monitoring (GM) neural network. I Dr. Karádi Zoltán The glucose-monitoring (GM) neural network. II Dr. Karádi Zoltán 201 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 The glucose-monitoring (GM) neural network. III Dr. Karádi Zoltán Eating and metabolic disorders: obesity, anorexia nervosa, diabetes mellitus, metabolic syndrome. I Dr. Karádi Zoltán Eating and metabolic disorders: obesity, anorexia nervosa, diabetes mellitus, metabolic syndrome. II Dr. Karádi Zoltán Feeding and metabolic disorders: disturbance of the GM system? Dr. Karádi Zoltán Practices Seminars Exam topics/questions According to topics of the lectures Participants 202 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-ANC MEDICAL ENGLISH 2/C - WRITING UP RESEARCH - HOW TO PREPARE AND READ MEDICAL JOURNAL ARTICLES DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 4 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 200 Prerequisites: no prerequisites Topic Preparing for processing biomedical research articles written in English required during the premedical, medical, preclinical and clinical courses. Preparing for writing up research in biomedical research articles in English Conditions for acceptance of the semester Participation in practicles is obligatory. Absences exceeding 15% but below 25% of the total number of contact hours can be excused by the group tutor. In case absences exceed 25% of the total number of contact hours the course must be regarded as uncompleted. Mid-term exams Making up for missed classes To be discussed with the course tutor in each individual case. Reading material - Obligatory literature - Literature developed by the Department Weissberg, R. & Buker, S.: Writing Up Research. Experimental Research Report Writing for Students of English, Englewood Cliffs: Prentice Hall Regents, 1990 in-house hand-outs - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 The format of MRAs Dr. Rébék-Nagy Gábor The format of MRAs Dr. Rébék-Nagy Gábor The logical cycle of inductive inquiry Dr. Rébék-Nagy Gábor The logical cycle of inductive inquiry Dr. Rébék-Nagy Gábor The genre of MRA Dr. Rébék-Nagy Gábor The genre of MRA Dr. Rébék-Nagy Gábor The discourse community Dr. Rébék-Nagy Gábor The discourse community Dr. Rébék-Nagy Gábor Non-native writers` paradox Dr. Rébék-Nagy Gábor Non-native writers` paradox Dr. Rébék-Nagy Gábor Psycholinguistic aspects of the MRA Dr. Rébék-Nagy Gábor Psycholinguistic aspects of the MRA Dr. Rébék-Nagy Gábor 203 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Socio-cultural aspects of the MRA Dr. Rébék-Nagy Gábor Socio-cultural aspects of the MRA Dr. Rébék-Nagy Gábor The lexis and grammar of MRAs Dr. Rébék-Nagy Gábor The lexis and grammar of MRAs Dr. Rébék-Nagy Gábor The introduction section Dr. Rébék-Nagy Gábor The introduction section Dr. Rébék-Nagy Gábor The methods section Dr. Rébék-Nagy Gábor The methods section Dr. Rébék-Nagy Gábor The discussion section Dr. Rébék-Nagy Gábor The discussion section Dr. Rébék-Nagy Gábor The abstract Dr. Rébék-Nagy Gábor The abstract Dr. Rébék-Nagy Gábor Politeness phenomena in MRAs Dr. Rébék-Nagy Gábor Modality in MRAs Dr. Rébék-Nagy Gábor Course evaluation Dr. Rébék-Nagy Gábor Course evaluation Dr. Rébék-Nagy Gábor Practices Seminars Exam topics/questions 1/ Four quizzes 2/ Essay on the theory of medical research article writing 3/ Annotating a medical research article Participants Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE) 204 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-BDK MOLECULAR BIOLOGICAL METHODS IN CANCER RESEARCH DR. ZSUZSA RÁKOSY, assistant professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 12 lectures + 2 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAA-MB2 completed Topic Cancers is one of the major cause of death worldwide, in addition the incidence of this disease has been increasing. Research is needed to identify the unknown risk factors and to understand the molecular basis of carcinogenesis to provide new tools and insights into aetiology and prevention of this malignancy. The course is going to familiarize the students with the modern molecular biological methods and their role in the cancer research field including the most recent clinical and preventive aspects. The lectures will present novel approaches in the characterization of the molecular alterations and will provide global perspective and knowledge on high throughput and targeted molecular biological techniques in the cancer research. Conditions for acceptance of the semester Participation in lectures and practicals is obligatory which is registered. Absences should not exceed 15% of practicals (2x45 min). Otherwise signature of grade book is denied. Mid-term exams Written test will take place on the last practical. Making up for missed classes There is no make-up class. Reading material - Obligatory literature - Literature developed by the Department ppt presentation (CooSpace) - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 In situ hybridization techniques I Dr. Rákosy Zsuzsa In situ hybridization techniques II Dr. Rákosy Zsuzsa Microarray techniques I.: Detection of genetic and epigenetic alterations I Dr. Rákosy Zsuzsa Microarray techniques I.: Detection of genetic and epigenetic alterations II Dr. Rákosy Zsuzsa Microarray techniques II. : Identification of RNA and protein expression changes I Dr. Rákosy Zsuzsa Microarray techniques II. : Identification of RNA and protein expression changes II Dr. Rákosy Zsuzsa High throughput sequencing, role of new generation sequencing systems in the cancer research I Dr. Rákosy Zsuzsa High throughput sequencing, role of new generation sequencing systems in the cancer research II Dr. Rákosy Zsuzsa In vitro gene manipulations I Dr. Rákosy Zsuzsa In vitro gene manipulations II Dr. Rákosy Zsuzsa 205 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 Animal models and 3 dimensions model systems I Dr. Rákosy Zsuzsa Animal models and 3 dimensions model systems II Dr. Rákosy Zsuzsa Practices 1 2 The thousands face of PCR I The thousands face of PCR II Seminars Exam topics/questions Participants Dr. Rákosy Zsuzsa (RAZVAAP.PTE) 206 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-BIN BIOINFORMATICS DR. LÁSZLÓ GRAMA, assistant professor Department of Biophysics Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 0 lectures + 14 practices + 14 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 18 Prerequisites: OAA-MB1 completed Topic According to a simple definition bioinformatics is molecular biology on a computer. Today, also due to the Human Genome Project, an incredible amount of information is available on our genes and proteins. What can we use this information for? The aim of bioinformatics is to organize this information and to help us find and analyze the relevant data. Our course provides an introduction to these. We will seek answers to questions like: - how can we find the DNA and amino acid sequence of a given protein on the internet? - how can we distinguish coding and non-coding regions of a gene? - how can we predict the properties of DNA and protein molecules based on their sequence? - how can we design a protein cloning experiment? - how similar is the same protein found in men and mice? - how can the 3D structure of a protein be predicted? - how can we visualize and manipulate the 3D structure of a protein? During the course we will not only discuss the theoretical background of the above (and many other) questions, but students will also be able to try out all these methods in practice. Conditions for acceptance of the semester Maximum of three absences. Mid-term exams Making up for missed classes None. Reading material - Obligatory literature - Literature developed by the Department http://biofizika.aok.pte.hu - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction Molecular biology basics Introduction to basic tools Protein databases Nucleotide databases Gene and genome databases. Restriction mapping PCR primer design. Plasmid maps Designing a cloning project 1 Designing a cloning project 2 Similarity searches (BLAST) Multiple sequence alignments. Phylogenetic trees 3D protein structures Protein structure prediction, computer simulations Bibliography databases (PubMed), working with references 207 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction Molecular biology basics Introduction to basic tools Protein databases Nucleotide databases Gene and genome databases. Restriction mapping PCR primer design. Plasmid maps Designing a cloning project 1 Designing a cloning project 2 Similarity searches (BLAST) Multiple sequence alignments. Phylogenetic trees 3D protein structures Protein structure prediction, computer simulations Bibliography databases (PubMed), working with references Exam topics/questions http://biofizika.aok.pte.hu Participants Dr. Grama László (GRLHAAO.PTE), Dr. Kengyel András Miklós (KEAFACO.PTE), Dr. Talián Csaba Gábor (TACRAAO.PTE) 208 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-BOT THEORY AND PRACTICE OF EVIDENCE-BASED MEDICINE DR. TAMÁS DECSI, professor Department of Paediatrics Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 24 Prerequisites: no prerequisites Topic Evidence-based medicine (EBM) offers practical tools to solve the practical problems arising in clinical settings as well as in outpatient care. This course is aimed not only to summarise the basic knowledge of EBM, but to provide practical examples of the usefulness of EBM as well. Formulating of clinical questions, literature search strategies as well as critical appraisal of papers revealed by the search is discussed in detail. Conditions for acceptance of the semester Missing more than 4 hours of teaching excludes the student from the course. Mid-term exams Making up for missed classes Missing not more than four hours may be amended by studying at home and answering specific questions of the tutor. Reading material - Obligatory literature - Literature developed by the Department The teaching material will be made electronically available for the students. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Formulating clinical questions (PICO strategy) Dr. Decsi Tamás Searching electronic databases Dr. Decsi Tamás Randomised controlled trials Dr. Decsi Tamás Appraisal of randomised controlled trials Dr. Decsi Tamás Systematic reviews Dr. Decsi Tamás Appraisal of systematic reviews Dr. Decsi Tamás Clinical guidelines Dr. Decsi Tamás Appraisal of clinical guidelines Dr. Decsi Tamás Epidemiological studies Dr. Decsi Tamás Appraisal of epidemiological studies Dr. Decsi Tamás Health technology assessment Dr. Decsi Tamás Cost-benefit analysis Dr. Decsi Tamás Practical implication of the evidence Dr. Decsi Tamás Implementation of changes in health care Dr. Decsi Tamás 209 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions The individual performance of students will be follow-up during the course; the last hour of the course will be devoted to evaluating the readiness of the student to apply methods of EBM in practical settings. Participants Dr. Decsi Tamás (DETIAAK.PTE) 210 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-CSU MIRACLES OF LIVING MATERIALS („REALISTIC” BIOCHEMISTRY) DR. BALÁZS VERES, associate professor Department of Biochemistry and Medical Chemistry Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5– Prerequisites: no prerequisites Topic The aim of the course is to enlighten and uncover the biochemical background of those topics which are selected as recent „mainstream” natural science issues. The topic spectrum is wide enough to cover problems from synthetic biology through dopes in sport until toxins and poisons of plants, fungi and animals. There is a special session about the physical, chemical and medical Nobel prizes from the last decade to get insight to the hottest fields of natural sciences. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes There is no possibility to make up. Reading material - Obligatory literature - Literature developed by the Department Lecture slides (in pdf format) will be available for the students. WEB links and additional on line materials will be included as well. - Notes Lecture slides (in pdf format) will be available for the students. WEB links and additional on line materials will be included as well. - Recommended literature Lecture slides (in pdf format) will be available for the students. WEB links and additional on line materials will be included as well. Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Human genome project, gene therapy, epigenetics Dr. Veres Balázs DNA sequencing, PCR, CSI Dr. Veres Balázs Playing God: synthetic biology Dr. Veres Balázs You are what you eat: GMO Dr. Veres Balázs Superman: doping in sport and brain doping Dr. Veres Balázs Dependence: biochemistry of alcohol and drugs Dr. Veres Balázs Falling down: apoptosis, necrosis, autophagy Dr. Veres Balázs Cancer, AIDS: beyond therapy Dr. Veres Balázs Biochemistry of neurodegenerative disorders Dr. Veres Balázs Antibiotics: past, present, future Dr. Veres Balázs Home delivery: nanoparticles, liposomes Dr. Veres Balázs Nature strikes back: toxins of plants, fungi and animals Dr. Veres Balázs 211 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Ideas behind Nobel prizes I Dr. Veres Balázs Ideas behind Nobel prizes II Dr. Veres Balázs Practices Seminars Exam topics/questions Exam topics are the topics of the lectures during the course. Participants Dr. Veres Balázs (VEBAAB.T.JPTE) 212 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EKK HEALTH AND PHYSICAL ENVIRONMENT DR. TÍMEA VARJAS, assistant professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1– Prerequisites: no prerequisites Topic The course will provide an overview of the relation of men and some selected natural or built environments and their connection concerning health. Highlighted topics: human factor and ergonomics, work environment, urbanisation, physical risk factors, climate, illumination, electric smog, noise pollution. Conditions for acceptance of the semester Absences should not exceed 15% of lectures and practicals (2x45 min). Otherwise signature of grade book is denied. Examination: written test Mid-term exams Exam: test after the last lecture. Re-take exam in the exam period. Making up for missed classes Based on individual consideration Reading material - Obligatory literature - Literature developed by the Department PPT-presentations (CooSpace) - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Introduction, Human and physical environment Dr. Szabó István Urbanization; The effect of modern civilization on health Dr. Szabó István Human factors and Ergonomics Dr. Szabó István Human factors and Ergonomics Dr. Szabó István Ergonomics and anthropometry Dr. Szabó István Built environment; The environmental context of disability Dr. Szabó István Vision and lighting (illumination, display screen equipment) Dr. Szabó István Vision and lighting (illumination, display screen equipment) Dr. Szabó István Selected electromagnetic radiations and health – Electronic smog Dr. Szabó István Selected electromagnetic radiations and health – Electronic smog Dr. Szabó István Indoor climate and air quality Dr. Szabó István Indoor climate and air quality Dr. Szabó István 213 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Biometeorology Dr. Szabó István Hearing and noise, physical and psychological aspects Dr. Szabó István Practices Seminars Exam topics/questions Coospace Participants 214 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EMM MOLECULAR BASIS OF ENDOCRINE DISEASES DR. MARIETTA VÉRTES M, professor emeritus Department of Physiology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 50 Prerequisites: OAA-MB2 completed Topic Endocrinology is the study of hormones, their receptors and the intracellular signalling pathways they invoke. The aim of the program is to understand the effects of hormones on cellular growth and function and their implications in development of endocrine dysfunction. Explain the molecular and cellular abnormalities in common endocrine-based diseases. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Oral discussion, multiple choice questions from 6-6 hrs of course. Making up for missed classes Oral discussion of given chapter Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Greenstein B.: Endocrinology at a Glance, Springer 1999 Williams Textbook of Endocrinology, 2004 Goodman M: Basic Medical Endocrinology, 2000 Greenspan FS, Baxter JD: Basic and Clinical Endocrinology, 2003 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Disorders of endocrine system. Hypo- and hyperfunction Dr. Vértes M Marietta Disorders of endocrine system. Hypo- and hyperfunction Dr. Vértes M Marietta Defect in sensitivity to hormones. Approach to the patient with endocrine disease Dr. Vértes M Marietta Defect in sensitivity to hormones. Approach to the patient with endocrine disease Dr. Vértes M Marietta Laboratory and imaging studies. Endocrinologic evaluation of the hypothalamo-pituitary axis Dr. Vértes M Marietta Laboratory and imaging studies. Endocrinologic evaluation of the hypothalamo-pituitary axis Dr. Vértes M Marietta Pituitary disorders: adenomas, Hypopitutarism, hypothalamic dysfunction. Dr. Vértes M Marietta Pituitary disorders: adenomas, Hypopitutarism, hypothalamic dysfunction. Dr. Vértes M Marietta Hormonal disorders of growth. Dr. Vértes M Marietta Hormonal disorders of growth. Dr. Vértes M Marietta Disorders of the thyroid Dr. Vértes M Marietta Disorders of the thyroid Dr. Vértes M Marietta 215 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Goiter. Hypothyroidism. Dr. Vértes M Marietta Goiter. Hypothyroidism. Dr. Vértes M Marietta Hyperthyroidism. Autoimmune disorders Dr. Vértes M Marietta Hyperthyroidism. Autoimmune disorders Dr. Vértes M Marietta Hormonal dysfunction of carbohydrate, protein and fat metabolism Dr. Vértes M Marietta Hormonal dysfunction of carbohydrate, protein and fat metabolism Dr. Vértes M Marietta Disorders of pancreas Dr. Vértes M Marietta Disorders of pancreas Dr. Vértes M Marietta Glucocorticoids, Adrenal medulla Dr. Vértes M Marietta Glucocorticoids, Adrenal medulla Dr. Vértes M Marietta Neural and hormonal integration in control of fluid homeostasis Dr. Vértes M Marietta Neural and hormonal integration in control of fluid homeostasis Dr. Vértes M Marietta Antidiuretic hormones, Mineral corticoids, Atrial Natriuretic Hormones Dr. Vértes M Marietta Antidiuretic hormones, Mineral corticoids, Atrial Natriuretic Hormones Dr. Vértes M Marietta Exam Dr. Vértes M Marietta Exam Dr. Vértes M Marietta Practices Seminars Exam topics/questions Written exam, multiple choice questions from lectures Participants Dr. Kovács Kálmán András (KOKFAFO.PTE), Dr. Vértes M Marietta (VEMMAAP.PTE) 216 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EUP MANAGING SUCCESSFUL EU PROJECTS DR. JUDIT PONGRÁCZ, professor Department of Pharmaceutical Biotechnology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 14 lectures + 14 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: no prerequisites Topic The main objective of the project management course is to deepen project management theory, methods and practice of the participants. Participants will have the capability to development projects and prepare successful events individually. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes 1. Szabó Lajos - Gaál Zoltán: Project Success and Project Excellence. In: Sharing Knowledge and Success for the Future?, MMSupport GmbH. Bern, 2006 ISBN 978-3-9523151-01, pp. 193-198. 2. Joseph W. Weiss, Robert K. Wysocki: 5-Phase Project Management: A Practical Planning & Implementation Guide, AddisonWesley, 1992 - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Project life cycle Dr. Bognár Rita Role and tasks of the project manager Dr. Bognár Rita Project planning (Work packages, time management) Dr. Bognár Rita Human resource management (Project team members, coordination and communication) Dr. Bognár Rita Preparation and organisation of meetings, workshops, conferences Dr. Bognár Rita Project communication and dissemination Dr. Bognár Rita Financial management 1. (Main budget categories) Dr. Bognár Rita Financial management 2. Dr. Bognár Rita Procurement Dr. Bognár Rita Risk management Dr. Bognár Rita Reporting 1. (Project documentation) Dr. Bognár Rita Reporting 2. Dr. Bognár Rita Amendment Dr. Bognár Rita Monitoring, monitoring visit Dr. Bognár Rita 217 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Practical examples and case studies: Project life cycle Practical examples and case studies: Role and tasks of the project manager Practical examples and case studies: Project planning (Work packages, time management) Practical examples and case studies: Human resource management (Project team members, coordination and communication) Practical examples and case studies: Preparation and organisation of meetings, workshops, conferences Practical examples and case studies: Project communication and dissemination Practical examples and case studies: Financial management 1. (Main budget categories) Practical examples and case studies: Financial management 2. Practical examples and case studies: Procurement Practical examples and case studies: Risk management Practical examples and case studies: Reporting 1. (Project documentation) Practical examples and case studies: Reporting 2. Practical examples and case studies: Amendment Practical examples and case studies: Monitoring, monitoring visit Seminars Exam topics/questions CooSpace Participants Dr. Bognár Rita (BOREAA.K.JPTE) 218 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EXT EXTRACTION AND CHROMATOGRAPHIC TECHNIQUES IN MEDICINAL PLANT ANALYSIS DR. GYÖRGYI HORVÁTH, associate professor Department of Pharmacognosy Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 26 lectures + 0 practices + 2 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 20 Prerequisites: OAA-OR1 completed + OAA-OR2 completed Topic With the increasing demand for herbal medicinal products, nutraceuticals, and natural products for health care all over the world, medicinal plant extract manufacturers and essential oil producers have started using the most appropriate extraction and chromatographic technologies in order to produce and standardize extracts and essential oils of defined quality. The aim of this course is to introduce the most important extraction methods and chromatographic techniques used in the research of medicinal plants. Students should be able to apply the acquired knowledge in their medical or pharmaceutical practice. Task: To introduce state-of-the-art extraction techniques (maceration, infusion, digestion, decoction, percolation, Soxhlet, ultrasound extraction, supercritical fluid extraction, water and steam distillation, enfleurage, expression) and chromatographic analyses (column chromatography, thin layer chromatography, high pressure liquid chromatography) of medicinal plants and their role in the production of herbal medicines. Some applications, relating to different classes of substances, are presented to demonstrate the versatility of various chromatographic techniques. Requirements: students have to know the most frequent extraction and analytical techniques used in medicinal and aromatic plant research. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Criteria of acceptance of the semester: Satisfactory fulfilment of 1 written test based on the lectures. Students have to give a short oral presentation based on 1 article read by themselves. Making up for missed classes There is no possibility to make up for missed lecture and practice. Reading material - Obligatory literature - Literature developed by the Department PowerPoint presentations prepared by lecturers. - Notes - Recommended literature 1. Handa S.S., Khanuja S.P.S., Longo G., Rakesh D.D.: Extraction Technologies for Medicinal and Aromatic Plants, International Centre for Science and High Technology, Trieste, 2008 2. Reich E., Schibli A.: High-Performance Thin-Layer Chromatography for the Analysis of Medicinal Plants, Thieme, UK, 2007 3. Colegate S.M.: Bioactive Natural Products Detection Isolation and Structural Determination, CRC Press, 2008 4. Niessen W.M.A.: Liquid Chromatography - Mass Spectrometry, CRC Press, 2006 5. Nyiredy, Sz.: Planar Chromatography, Springer, Budapest, 2001. 6. Harris, DC.: Quantitative Chemical Analysis, WH. Freeman and Co., 7th edition, New York, 2007, 7. Schiedt K., Liaaen-Jensen S.: Isolation and Analysis, in Carotenoids Vol. 1A: Isolation and Analysis, Eds.: Britton G., LiaaenJensen S., Pfander H., Birkhäuser Verlag, Basel, 1995. Lectures 1 2 3 4 Introduction of the course requirements. An Overview of Extraction Techniques for Medicinal and Aromatic Plants. Dr. Horváth Györgyi Introduction of state-of-the-art extraction techniques: maceration, infusion, digestion, decoction, percolation, Soxhlet, ultrasound extraction, supercritical fluid extraction, water and steam distillation, enfleurage, expression. Dr. Horváth Györgyi Introduction to Analytical Separations. Dr. Benkő András Antal Techniques for the Purposes of Botanical Research. Dr. Benkő András Antal 219 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 Planar Chromatography: TLC. Dr. Benkő András Antal Role of Different Procedures and Test Systems in the Knowledge of Herbal Substances. Dr. Benkő András Antal Column Chromatography Systems: GC. Dr. Benkő András Antal Column Chromatography Systems: HPLC. Dr. Benkő András Antal Detectors Used in Different Separation Techniques and their Role in Qualitative and Quantitative Analysis. Dr. Benkő András Antal Classification of Detectors Based on their Sensitivity and Selectivity. Dr. Benkő András Antal Role of thin layer chromatography (TLC) in detecting microbiological processes: TLC-Bioautography. Dr. Horváth Györgyi Antimicrobial activity of essential oils using TLC-Bioautography. Dr. Horváth Györgyi Isolation and identification of carotenoids from medicinal plants. Dr. Molnár Péter Role of column liquid chromatography (CLC) in carotenoid research. Dr. Molnár Péter Extraction, separation and detection of carbohydrates from various plant samples, applying diverse chromatographic techniques. Dr. Bencsik Tímea Extraction, separation and detection of carbohydrates from various plant samples, applying diverse chromatographic techniques. Dr. Bencsik Tímea Identification of specific metabolites in herbal products. Adulterated dietary supplements. Dr. Bencsik Tímea Identification of specific metabolites in herbal products with TLC. Dr. Bencsik Tímea Isolation and Identification of flavonoids in medicinal plants. Dr. Papp Nóra Isolation and Identification of flavonoids in medicinal plants. Dr. Papp Nóra Comparative phytochemical studies on populations of medicinal plant taxa; their role in plant identification and in pharmacy. Dr. Papp Nóra Comparative phytochemical studies on populations of medicinal plant taxa; their role in plant identification and in pharmacy. Dr. Papp Nóra Student’s lecture. Dr. Bencsik Tímea Student’s lecture. Dr. Benkő András Antal Written test. Dr. Horváth Györgyi Written test. Dr. Horváth Györgyi Practices Seminars 1 2 Chromatographic seminar: GC. Chromatographic seminar: HPLC. Exam topics/questions The topics of the 1 written test are similar to the topics of the lectures. Participants Dr. Benkő András Antal (BEAQAAP.PTE) 220 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-JAV SIGNAL TRANSDUCTION DR. TIMEA BERKI, professor Department of Immunology and Biotechnology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 20 Prerequisites: OAA-IMM parallel Topic Novel antibodies against receptors, protein kinase inhibitors, and antisense oligonucleotides targeting both signal transduction and gene expression will predominate the therapeutic approaches in the coming decades. The course focus on the therapeutic potential for targeting cell signaling mechanisms with particular attention to cancer therapies and inflammatory signaling pathways as well as immunomodulation. General concepts of inter-and intracellular signal transduction: receptor-mediated signal transduction, cell surface receptors, steroid hormone and nuclear receptors and their cytoplasmic signal transduction and nuclear responses, apoptotic cell signaling will be discussed together with the novel approaches to drug discovery in signal transduction. Internationally known experts of the field guest lecturers from Hungarian universities are contributing in the course. Conditions for acceptance of the semester Maximum 3 absences allowed Mid-term exams Making up for missed classes Reading material - Obligatory literature 2. Gutkind, J. Silvio (ed.): Signal Transduction and Human Disease, John Wiley & Sons, Inc. - Literature developed by the Department www.immbio.hu - Notes 1. Gerhard Krauss: Biochemistry of Signal Transduction and Regulation, Finkel, Toren (ed.), Wiley - Recommended literature Frederick Marcus: Bioinformatics and Systems Biology: Collaborative Research and Resources, Springer, 2008 Lectures 1 2 3 4 5 6 7 8 9 10 Introduction, overlap with other disciplines Dr. Berki Timea Overview of extracellular signaling Dr. Berki Timea Families of extracellular receptors Dr. Boldizsár Ferenc Second messengers (cAMP) Dr. Boldizsár Ferenc Receptor tyrosine kinases Dr. Boldizsár Ferenc The Ca++ signal Dr. Boldizsár Ferenc Transcription factors Dr. Berki Timea Signaling in the specific immune system: B cell signaling. Dr. Berki Timea T cell activation and signaling Dr. Berki Timea Fcgamma and Fcepsilon Receptor signaling Dr. Berki Timea 221 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Tyrosine kinase-linked receptors I: cytokine/chemokine signaling Dr. Boldizsár Ferenc Tyrosine kinase-linked receptors II: growth factors Dr. Boldizsár Ferenc Receptors with intrinsic enzymatic activity (insulin, growth factors). Dr. Berki Timea G-protein-linked receptors (epinephrine, serotonin, glucagon). Dr. Berki Timea Signaling in tumor cells (EGF-R, Her-2R, adhesion molecules). Dr. Berki Timea Apoptosis signaling Dr. Berki Timea Ion-channel receptors (acetilcholine receptor). Cell-surface hormone receptors Dr. Berki Timea Intracellular/nuclear receptor signaling (steroid hormones and thyroxin). Dr. Boldizsár Ferenc Non-genomic steroid hormone signaling pathways. Dr. Boldizsár Ferenc Signaling in the innate immune system: CR and TLR signaling Dr. Berki Timea Receptor interactions, signaling cross-talk Dr. Berki Timea Wnt receptor signaling. Dr. Pongrácz Judit Role of signal transduction in cell differentiation Dr. Pongrácz Judit Adhesion molecule signaling Dr. Berki Timea Role of adhesion molecules in tumor progression Dr. Berki Timea Signaling in the nervous system Dr. Berki Timea Pharmacological influence of the signaling. Dr. Pethő Gábor Pharmacological influence of the signaling. Dr. Pethő Gábor Practices Seminars Exam topics/questions Participants 222 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MAF RELATIONSHIP BETWEEN INTRAUTERINE DEVELOPMENT AND ANATOMICAL SITUS DR. JUDIT HORVÁTH, associate professor Department of Anatomy Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 4 lectures + 0 practices + 8 seminars = total of 12 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAA-AA2 completed + OAA-EL1 completed + OAA-SF2 completed Topic Synthesis of previous anatomical and embryological knowledge, enlightening connections of embryological development, explaining the background of developmental malformations. Conditions for acceptance of the semester The course will be held on the 6th, 7th, 8th, 10th, 11th and 12th teaching week of the semester, 1x2 hours. Maximum of absences: 2 hours. Mid-term exams Making up for missed classes There is no possibility of making up the missed classes. Reading material - Obligatory literature Langman’s Medical Embryology - Literature developed by the Department http://an-server.pote.hu/OKT/K_Emb/eK_Emb.htm - Notes - Recommended literature Lectures 1 2 3 4 Intrauterine development in the first two months and the external body shape. Dr. Horváth Judit Development of the organs of the thoracic cavity – the embryological basis of the anatomical situs. Dr. Horváth Judit Development of the organs of the abdominal cavity – the embryological basis of the anatomical situs. Dr. Horváth Judit Development of the nervous system – the embryological basis of the macroscopy of the brain. Dr. Horváth Judit Practices Seminars 1 Intrauterine development in the first two months and the external body shape. 2 Intrauterine development in the first two months and the external body shape. 3 Development of the organs of the thoracic cavity – the embryological basis of the anatomical situs. 4 Development of the organs of the thoracic cavity – the embryological basis of the anatomical situs. 5 Development of the organs of the abdominal cavity – the embryological basis of the anatomical situs. 6 Development of the organs of the abdominal cavity – the embryological basis of the anatomical situs. 7 Development of the nervous system – the embryological basis of the macroscopy of the brain. 8 Development of the nervous system – the embryological basis of the macroscopy of the brain. Exam topics/questions http://an-server.pote.hu/OKT/K_Emb/eK_Emb.htm Participants Dr. Horváth Judit (HOJIAAO.PTE) 223 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MC2 METHODS IN MOLECULAR CELL BIOLOGY II DR. MARIANNA PAP, associate professor Department of Medical Biology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 12 lectures + 16 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 1 – 20 Prerequisites: OAA-MB2 completed Topic The main objective of the course to improve theoretical knowledge and practical skills of students. The course covers the most important technics used in molecular cell biology. On the small-group discussions theoretical background of molecular cell biology methods is described and discussed. On the practicals students perform basic experiments used in the Medical Biology Department. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes Individually discussed Reading material - Obligatory literature - Literature developed by the Department Hand-outs prepared by the Medical Biology Department - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Apoptosis methods (DNA-fragmentation, morphological methods, detection of biochemical changes) Dr. Pap Marianna Apoptosis methods (DNA-fragmentation, morphological methods, detection of biochemical changes) Dr. Pap Marianna Protein methods (Western blot, immunprecipitation, immunhistochemistry) ifj. Dr. Sétáló György Protein methods (Western blot, immunprecipitation, immunhistochemistry) ifj. Dr. Sétáló György PCR I. (detection methods, types of primers and probes) Dr. Pap Marianna PCR I. (detection methods, types of primers and probes) Dr. Pap Marianna PCR II. (primer and probe design, uses of databases) Dr. Pap Marianna PCR II. (primer and probe design, uses of databases) Dr. Pap Marianna Analysis of RNA (RNA isolation, electrophoresis, RNase protection assay, S1 nuclease mapping) Dr. Pap Marianna Analysis of RNA (RNA isolation, electrophoresis, RNase protection assay, S1 nuclease mapping) Dr. Pap Marianna Radioactive isotopes used in molecular cell biology (3H, 32P, 35S-labeling, probe labeling) Dr. Pap Marianna Test Dr. Pap Marianna 224 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Apoptosis assay (counting cells) Apoptosis assay (treatment of cells) Apoptosis assay (fixation, staining of nuclei) Apoptosis assay (check nuclei morphology by confocal laser scanning microscopy) Western blot (counting cells) Western blot (treatment of cells) Western blot (cell lysis, measurement of protein concentration) Western blot (cell lysis, measurement of protein concentration) Western blot (preparation of the gel) Western blot (preparation of the gel) Western blot (loading and running the gel, set up the transfer) Western blot (loading and running the gel, set up the transfer) Western blot (blocking, adding primary- and secondary antibodies, washing steps) Western blot (blocking, adding primary- and secondary antibodies, washing steps) Western blot (blocking, adding primary- and secondary antibodies, washing steps) Western blot (detection, densitometry) Seminars Exam topics/questions Participants Kiss Katalin (KIKFABO.PTE), Németh Mária (NEMGAAT.PTE), Varga Judit (VAJGACT.PTE) 225 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MEA POISONOUS AND VENOMOUS ANIMALS, ANIMAL POISONINGS DR. GELLÉRT GERENCSÉR, assistant lecturer Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 25 Prerequisites: no prerequisites Topic Worldwidely more and more people keep those animals (with or without permission) which are capable to cause severe poisonings. Nevertheless more and more people traveling abroad which means high risk to get animal-related toxicity. The course tries to familiarize the students with the theoretical and practical background of poisoning caused by the most important animal groups, including the venom characteristics, pathophysiology and basic medical care actions. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Written test Making up for missed classes No possibility Reading material - Obligatory literature - Literature developed by the Department In CooSpace - Notes - Recommended literature Steve Backshall: Venomous Animals of the World, Johns Hopkins University Press, 2007 Dietrich Mebs: Venomous and Poisonous Animals: A Handbook for Biologists, Toxicologists and Toxinologists, Physicians and Pharmacists, Medpharm; 2002 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Introduction and basic concepts Bérczi Bálint Dániel Statistical data on animal poisonings Bérczi Bálint Dániel Sponges, Cnidarians envenomations Bérczi Bálint Dániel Annelids, Molluscs and Echinoderms poisoning Bérczi Bálint Dániel Arthropods, Centipedes poisoning Bérczi Bálint Dániel Poisoning caused by insects (butterflies, diptera, ants, bees and wasps) Bérczi Bálint Dániel Arachnid poisoning (spiders, scorpions, ticks and mites) Bérczi Bálint Dániel Fish and Amphibians poisoning Bérczi Bálint Dániel Reptiles and lizards poisoning Bérczi Bálint Dániel Snakebite poisoning I Bérczi Bálint Dániel Snakebite poisoning II Bérczi Bálint Dániel Poisoning caused by Birds and Mammals Bérczi Bálint Dániel 226 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 The general medical care of animal poisonings Dr. Berényi Károly Medical care and treatment of snakebite poisonings Dr. Berényi Károly Practices Seminars Exam topics/questions In CooSpace Participants 227 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MMR NUCLEAR MAGNETIC RESONANCE FOR DUMMIES DR. ZOLTÁN BERENTE, associate professor Department of Biochemistry and Medical Chemistry Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 20 Prerequisites: OAA-BI2 completed + OAA-BK1 completed Topic Nuclear magnetic resonance offers an exceptionally versatile, non-invasive and non-destructive way for studying intact living organisms. However, magnetic resonance imaging (MRI), and especially NMR spectroscopy, are strikingly underrepresented among diagnostic methods. It may be due to regarding the method a strange, obscure if not suspicious „black box”; this way of thinking is far more widespread among graduated medical doctors than it should be. Take the courage, the time and the effort to take a closer look at nuclear magnetic resonance. Let’s start from scratch and let’s understand what your fellow students do not bother to understand: what happens with the sample in the magnet during an NMR or MRI experiment, how does it happen and why. The course covers the theoretical background of the medical diagnostic (imaging and biomarkers) and drug industrial (drug development, drug analysis) applications of nuclear magnetic resonance with a problem-based attitude and case studies. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams None Making up for missed classes On the judgement of the instructor. Reading material - Obligatory literature http://cis.rit.edu/htbooks/nmr http://cis.rit.edu/htbooks/mri - Literature developed by the Department - Notes - Recommended literature R. A. de Graaf: In vivo NMR Spectroscopy, Wiley, 1998 http://www.imaios.com/en/e-Courses/e-MRI http://www.magnetic-resonance.org/ http://eprints.drcmr.dk/37/1/MRI_English_a4.pdf Lectures 0 0 0 0 0 0 0 0 The NMR phenomenon. Excitation, relaxation and signal formation Dr. Berente Zoltán Fourier-transform pulse NMR: Theory and practice Dr. Berente Zoltán Structure elucidation of small molecules 1. One-dimensional techniques based on coupling through chemical bonds or through the space. Dr. Berente Zoltán Structure elucidation of small molecules 2. NMR in more dimensions, strategy of structure analysis Dr. Berente Zoltán Structure elucidation of small molecules 3. NMR in drug development and in drug analysis Dr. Berente Zoltán Structure elucidation of macromolecules. Intramolecular and intermolecular interactions, structure-activity relationship Dr. Berente Zoltán Study of energy metabolism using 31P NMR spectroscopy Dr. Berente Zoltán Study of fuel metabolism using 13C NMR spectroscopy Dr. Berente Zoltán 228 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 0 0 0 0 0 0 Applications of NMR spectroscopy of other nuclei (19F, 23Na, 87Rb) in life sciences Dr. Berente Zoltán Statistical NMR spectroscopy: searching for biomarkers Dr. Berente Zoltán Basics of MR imaging Dr. Berente Zoltán Current MR imaging techniques Dr. Berente Zoltán Localised (volume selective) NMR spectroscopy Dr. Berente Zoltán NMR in solid phase: study of biological membranes Dr. Berente Zoltán Practices Seminars Exam topics/questions Participants Dr. Berente Zoltán (BEZLAAP.PTE) 229 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MRK MOLECULAR AND CELLULAR MR IMAGING DR. ZOLTÁN BERENTE, associate professor Department of Biochemistry and Medical Chemistry Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 4 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 24 Prerequisites: OAA-BI2 completed + OAA-BK1 completed Topic Magnetic resonance imaging (MRI) has been known so far mostly as a whole-body imaging technique. Since the technology already allows to obtain MR signal not only from water, but also substances of significantly lower concentration. The course covers the concepts, basic theory and known limits of current MR imaging methods on molecular probes and their applications in frequent disorders (e.g. tumors, diabetes, inflammations) or in „hot topics” (e.g. stem cells). Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes On the judgement of the tutor Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature R. A. de Graaf: In vivo NMR Spectroscopy, Wiley, 1998 M.M.J. Modo, J.W.M. Bulte: Molecular and Cellular MR Imaging, CRC Press, 2007 http://cis.rit.edu/htbooks/nmr http://cis.rit.edu/htbooks/mri http://www.imaios.com/en/e-Courses/e-MRI http://www.magnetic-resonance.org/ http://eprints.drcmr.dk/37/1/MRI_English_a4.pdf Lectures 1 2 3 4 5 6 7 8 9 10 11 The NMR phenomenon, excitation and signal formation, relaxation Dr. Berente Zoltán Theory and practice of the Fourier transform NMR technique Dr. Berente Zoltán Basics of MR imaging Dr. Berente Zoltán Contrast in MRI, contrast agents Dr. Berente Zoltán Molecular and functional MRI of cancer Dr. Berente Zoltán Molecular MRI of atherosclerosis Dr. Berente Zoltán Molecular MRI of apoptosis Dr. Berente Zoltán Molecular MRI of reporter genes Dr. Berente Zoltán Pharmacological MRI Dr. Berente Zoltán Cellular Imaging of macrophage activity in infection, inflammation and in stroke Dr. Berente Zoltán Cellular and molecular MR Imaging of the diabetic pancreas Dr. Berente Zoltán 230 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 MR tracking of stem cells Dr. Berente Zoltán Cellular imaging of cell transplants Dr. Berente Zoltán Project presentations Dr. Berente Zoltán Practices Seminars Exam topics/questions Participants 231 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-OBQ MEDICAL BIOCHEMISTRY - QUESTIONS AND ANSWERS DR. ZOLTÁN BERENTE, associate professor Department of Biochemistry and Medical Chemistry Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5– Prerequisites: OAA-BKA completed Topic The course is aimed to support the successful accomplishment of the final exam „Medical Biochemistry”. In the classroom the brief summary of the theory related to the actual topic will be followed by discussing explicit questions (multiple choice and open questions as well) in order to deepen the understanding of the material along with the preparation for the written exam. In order to help preparation the topics of this course will discuss the lectures and practices of the main course, but shifted in time. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes No opportunity to make-up missed classes. Reading material - Obligatory literature - Literature developed by the Department The lecture slideshows will be available on CooSpace after the class. - Notes - Recommended literature http://bcs.whfreeman.com/lehninger5e - Interactive Quizzes http://bcs.whfreemn.com/berg7e - Online Quizzing T.A. Swanson, S.I. Kim, M.J. Glucksman: Biochemistry, Molecular Biology & Genetics, 5th edition, Lippincott Williams & Wilkins, 2010. Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Introduction: What makes „Medical biochemistry” medical? Dr. Berente Zoltán Introduction 2: Though „Medical Biochemistry” is „medical”, it is still „biochemistry” Dr. Berente Zoltán Molecular background of disorders 1: Genome level alterations and their detection Dr. Veres Balázs Molecular background of disorders 2: Transcriptome level alterations and their detection Dr. Veres Balázs Molecular background of disorders 3: Proteome level alterations and their detection Dr. Jakus Péter Molecular background of disorders 4: Metabolome level alterations and their detection Dr. Jakus Péter Signal transduction 1 Dr. Veres Balázs Signal transduction 2 Dr. Veres Balázs The birth and death of cells Dr. Debreceni Balázs Tumour biochemistry Dr. Debreceni Balázs Biochemistry of nutrition 1 Dr. Berente Zoltán Biochemistry of nutrition 2 Dr. Berente Zoltán 232 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Carbohydrate metabolism: structure-activity relationships Dr. Agócs Attila Carbohydrate metabolism: enzymatic and hormonal regulation Dr. Agócs Attila Carbohydrate metabolism: organ and organelle specific issues Dr. Lengyel Anna Carbohydrate metabolism: pathobiochemical issues Dr. Lengyel Anna Lipid metabolism: structure-activity relationships Dr. Tapodi Antal Lipid metabolism: enzymatic and hormonal regulation Dr. Tapodi Antal Lipid metabolism: organ and organelle specific issues Dr. Bognár Zita Lipid metabolism: pathobiochemical issues Dr. Bognár Zita Protein and nucleotide metabolism: structure-activity relationships Dr. Jakus Péter Protein and nucleotide metabolism: enzymatic and hormonal regulation Dr. Jakus Péter Protein and nucleotide metabolism: organ and organelle specific issues Dr. Berente Zoltán Protein and nucleotide metabolism: pathobiochemical issues Dr. Berente Zoltán Biochemical background of acquired metabolic diseases 1 Dr. Kovács Krisztina Biochemical background of acquired metabolic diseases 2 Dr. Kovács Krisztina Test Dr. Berente Zoltán Test Dr. Berente Zoltán Practices Seminars Exam topics/questions The semester test questions will be selected from the problems discussed in the classroom. Participants 233 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-PCS BONE PATHOLOGY DR. LÁSZLÓ MÁRK, associate professor Department of Biochemistry and Medical Chemistry Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 26 lectures + 0 practices + 0 seminars = total of 26 hours Course headcount limitations (min.-max.): 3 – 100 Prerequisites: no prerequisites Topic The course gives an overall review about the observable pathological alterations of the human remains with their diagnostic possibilities as well as their interpretation. Topics: Chemical composition of human bone tissue. Sex determination techniques. Life determination. Congenital alterations. Traumatic morphology. Trepanations. Mycobacterial infections. Tuberculosis. Lepra Syphilis. The Pest. Bone tumors, osteocarcinoma. Joint diseases. Oral paleopathology. Molecular biomarker discovery. Evolution of human pathogenes. Evolution of Mycobacterium. Conditions for acceptance of the semester Written exam. Max. absences: 20%. Mid-term exams None Making up for missed classes Not possible. Reading material - Obligatory literature - Literature developed by the Department Lecture slides and notes. - Notes - Recommended literature A.C. Aufderheide: Cambrige Encyclopedia of Human Paleopathology, 1998 Human Paleopathology Eds. Ortner, Aufderheide. 2001. Palfi et al: Tuberculosis Past and Present, 1999 Lectures 1 2 3 Introduction Dr. Márk László The paleopathology, an interdisciplinary science Dr. Márk László The paleopathology, an interdisciplinary science Dr. Márk László 234 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 Chemical composition and biochemistry of the bone tissue Dr. Márk László Chemical composition and biochemistry of the bone tissue Dr. Márk László Sex determination techniques Dr. Márk László Lifetime determination Dr. Márk László Congenital alterations. Trauma Dr. Márk László Trepanations Dr. Márk László Tuberculosis Dr. Márk László Tuberculosis Dr. Márk László Lepra Dr. Márk László Lepra Dr. Márk László Syphilis Dr. Márk László Syphilis Dr. Márk László The Pest Dr. Márk László The Pest Dr. Márk László Osteo-necrotic alterations, dystrophies Dr. Márk László Osteocarcinoma, bone tumors Dr. Márk László Joint diseases Dr. Márk László Joint diseases Dr. Márk László Oral paleopathology Dr. Márk László Determination of molecular biomarkers Dr. Márk László Paleoproteomics. Evolution of the human pathogenes Dr. Márk László Exam Dr. Márk László Exam Dr. Márk László Practices Seminars Exam topics/questions Chemical composition of human bone tissue. Sex determination techniques. Life determination. Congenital alterations. Traumatic morphology. Trepanations. Mycobacterial infections. 235 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Tuberculosis. Lepra. Syphilis. The Pest. Bone tumors, osteocarcinoma. Joint diseases. Oral paleopathology. Molecular biomarker discovery. Evolution of human pathogenes. Evolution of Mycobacterium. Participants 236 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-TD2 STUDENT PROJECT RESEARCH 2 DR. PÉTER BALOGH, associate professor Undergraduate Research Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 4 Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours Course headcount limitations (min.-max.): 1 – 300 Prerequisites: OAF-TD1 completed Topic The aim of this subject is to nurture and promote the activity of students sufficiently motivated to perform biomedical project research. The students may progressively enrol to four parts in four separate semesters, for the total credit value of 8. For acknowledging the 3rd and 4th (elective) parts, the student must train research student novice(s). The subject’s administrator is the actual Chairman of the Students’ Research Society (SRS) of the Faculty of Medicine. Conditions for acceptance of the semester To enrol this course a registered SRS membership is mandatory. Acknowledging the course requires (a) either first-author presentation of work at a Students’ conference (UP or elsewhere) or Dean’s assay, or presentation at any professional conference relevant to the research field, or (b) progress report on the work performed or demonstrating expertise at the methodology employed before the Tutor and the Chairman of SRS. Grades will be accorded corresponding to the criteria set out in the Rules and Regulations of SRS. For detailed requirements please read the following document: http://aok.pte.hu/run/download2.php?idf=11791&nyelv=eng Mid-term exams Making up for missed classes Not applicable. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Not applicable Lectures Practices 1-24 Research Seminars Exam topics/questions Not applicable Participants Dr. Balogh Péter (BAPOAGP.PTE) 237 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-TKE THE ETHICS OF SCIENTIFIC RESEARCH TIBOR SZOLCSÁNYI, assistant professor Department of Behavioural Sciences Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: no prerequisites Topic The results of scientific researches have a great social impact and therefore the ethical problems raised by the practice of scientific researches are significant problems not only for the researchers, but for the wider society as well. The seminar helps to clarify the basic ethical, legal and philosophical concerns of medical research. During the semester the following subjects will be discussed: the criterions of rationality, reasoning and ethically correct debate, the characteristics and norms of scientific cognition, the ethics of scientific publication, the ethical and legal concerns of human and animal experimentation, neuroethical examples of the social impact of medical researches. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department Additional materials: CooSpace - Notes - Recommended literature John Ziman: Is Science Losing its Objectivity?, Nature, Vol. 382, August 1996, p.751-754. David Miller: Being an Absolute Skeptic, Science, Vol. 284, 1999 June, p.1625-1626. Dale J. Benos et al: Ethics and Scientific Publication, Advances in Physiological Education, 29: 59-74, 2005. Laura Bonetta: The Aftermath of Scientific Fraud, Cell, 2006 Mar 10; 124 (5):873-5. Larry D. Claxton: Scientific Authorship, Mutation Research/Reviews in Mutation Research, Volume 589, Issue 1, January 2005, p. 17-45. Porter DG: Ethical Scores for Animal Experiments, Nature, Vol. 356, March 1992, p.101-102. Peter Singers: Practical Ethics, Cambridge University Press, Cambridge, 1979, Equality for animals?, p.48-72. Tom Regan: Empty Cages: Animals Rights and Vivisection, Contemporary Debates in Applied Ethics, edited by Andrew I. Cohen and Christopher Heath Wellman , Blackwell Ltd, 2005, p.77-91. Martha J. Farah: Emerging Ethical Issues in Neuroscience, Nature Neuroscience, 5/11, 2002,1123-1129. Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction Introduction Rationality and ethics Rationality and ethics Rationality and ethics Rationality and ethics The methodology of scientific research in natural sciences, and its ethical implications The methodology of scientific research in natural sciences, and its ethical implications The methodology of scientific research in natural sciences, and its ethical implications The methodology of scientific research in natural sciences, and its ethical implications The ethical concerns of clinical trials The ethical concerns of clinical trials The ethical concerns of clinical trials The ethical concerns of clinical trials 238 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Ethical problems raised by animal experimentation Ethical problems raised by animal experimentation The placebo effect The placebo effect Ethics and scientific achievement Ethics and scientific achievement Gene-ethics Gene-ethics II. The ethics of stem cell research The ethics of stem cell research II. Neuroethical examples of the social impact of medical research Summarizing discussion Test Test Exam topics/questions Participants Dr. Szolcsányi Tibor (SZTAAJ.B.JPTE) 239 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-VAA IRON METABOLISM: FROM MOLECULAR MECHANISMS TO CLINICAL CONSEQUENCES DR. EDINA PANDUR, assistant professor Department of Pharmaceutical Biology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 4 – 30 Prerequisites: no prerequisites Topic During the course we will discuss the role of iron in the metabolism. We will deal with the iron demand of microorganisms and with the role of iron in the protective mechanisms against bacterial infections. The function of influencing factors of iron metabolism, their effects and crosstalk between them will be discussed in detail. The roles of iron containing proteins and their functions will be talked over. During the course we will emphasize the disorders of iron metabolism (iron deficiency, iron overload), their genetic backgrounds and their therapies. Based on the most actual findings the role of iron in the development of neurodegenerative diseases (Parkinson’s disease, Alzheimer’s disease and Huntington’s disease) will be also discussed. Conditions for acceptance of the semester Max. 1 absence Mid-term exams Making up for missed classes Personal consultation Reading material - Obligatory literature - Literature developed by the Department The educational materials will be uploaded to CooSpace. - Notes - Recommended literature Robert Crichton: Iron Metabolism – From Molecular Mechanisms to Clinical Consequences Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Solution chemistry of iron, interactions with other metal ions. The Importance of Iron for Biological Systems: haemoproteins, iron-sulfur proteins, other iron containing proteins Microbial Iron Transport and Metabolism Iron uptake by yeasts Cellular Iron Uptake and Export in Mammals: iron transporters Intracellular Iron Storage and Biomineralisation: ferritin, haemosiderin Intracellular Iron Metabolism and Cellular Iron Homeostasis I: Labile iron pool, mitochondrial iron uptake and metabolism haem biosynthesis Intracellular Iron Metabolism and Cellular Iron Homeostasis II: synthesis of iron-sulfur clasters, functions of iron responsive elements and iron regulatory proteins Iron Absorption in Man: functions of luminal factors Regulation of Systemic Iron Balance Pathophysiology of Iron Deficiency and Iron Overload: Acquired and Genetic Disorders of Iron Metabolism, haemochromatosis, thalassemias, secondary iron overload, anemias Iron and oxidative stress: cytoprotective enzymes, antioxidants, aging, role of the immune system Brain iron metabolism, the role of iron in neurodegenerative diseases Exam Exam topics/questions Participants Dr. Pandur Edina (PAEFAA.T.JPTE), Poór Viktor Soma (POVFAB.T.JPTE), Varga Edit (VAEQABT.PTE) 240 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-VSP URINARY STEROID PROFILES DR. ANITA BUFA, assistant professor Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 4 Number of hours/semester: 7 lectures + 7 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1–6 Prerequisites: OAA-OR2 completed Topic The participants are going to be familiarised theoretically and practically with: - pre-treatment of urine sample - qualitative and quantitative analysis of 24 androgen, progesterone and corticoid metabolites by gas chromatography using mass selective detector - evaluation of urinary steroid profiles Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams The course ends with a brief written report. Making up for missed classes Consultation with course director is required. Reading material - Obligatory literature - Literature developed by the Department It is going to be available on Coospace. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 Urinary steroid metabolites Dr. Bufa Anita Sample pre-treatment of urine Dr. Bufa Anita Gas chromatography Dr. Bufa Anita Mass spectrometry Dr. Bufa Anita Qualitative analysis of urinary steroid metabolites Dr. Bufa Anita Quantitative analysis of urinary steroid metabolites Dr. Bufa Anita Evaluation of urinary steroid profile Dr. Bufa Anita Practices 1 2 3 4 5 6 7 Solid-phase extraction of urinary steroid metabolites Enzymatic hydrolysis of urinary steroid metabolites Derivatization I of urinary steroid metabolites Derivatization II of urinary steroid metabolites Chromatographic cleaning Determination of urinary steroid profiles by GC-MS technic Qualitative and quantitative analysis of urinary steroid metabolites 241 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions The necessary information is going to be presented on the course. Participants Dr. Bufa Anita (BUAEAA.T.JPTE) 242 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-ABE INBORN ERRORS OF METABOLISM DR. TAMÁS DECSI, professor Department of Paediatrics Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 24 Prerequisites: no prerequisites Topic Inborn errors of metabolism represent rare, but altogether important diseases of paediatrics. Significant developments in therapeutic modalities during the last decade led to major improvement in the prognosis of the inherited diseases of metabolism. This course summarises basic knowledge about the diagnostics and therapy of inborn errors of metabolism. Practical examples of patients treated for these diseases in the Department of Paediatrics serve for discussing not only the way to diagnosis, but the long-term clinical care as well. Conditions for acceptance of the semester Missing more than four hours of teaching excludes the student from the course. The performance of the students will be continuously evaluated during the course. Mid-term exams Making up for missed classes Missing from maximum of four hours of teaching can be amended by reading the teaching material at home and answering questions related to the missed topic. Reading material - Obligatory literature - Literature developed by the Department The teaching material will be handed out at the course. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Importance of inborn errors of metabolism in paediatrics Dr. Decsi Tamás Clinical signs and symptoms of inborn errors of metabolism Dr. Decsi Tamás General considerations in amino acid metabolism disorders Dr. Decsi Tamás Disturbances of phenylalanin metabolism Dr. Decsi Tamás Disturbances of tyrosin metabolism Dr. Decsi Tamás Disturbances of homocysteine metabolism Dr. Decsi Tamás General considerations in carbohydrate metabolism disorders Dr. Decsi Tamás The role of family physicians in the treatment of inborn errors of metabolism Dr. Decsi Tamás Current principles of treating inborn errors of metabolism Dr. Decsi Tamás Ornithin transcarbamylase defect Dr. Decsi Tamás General considerations in urea cycle disorders Dr. Decsi Tamás Fructose intolerance Dr. Decsi Tamás 243 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Disturbances of galactose metabolism Dr. Decsi Tamás Glycogenoses Dr. Decsi Tamás Practices Seminars Exam topics/questions The performance of the students will be continually evaluated during the course. Participants Dr. Decsi Tamás (DETIAAK.PTE) 244 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-COP PATHOPHYSIOLOGY OF CHRONIC OBSTRUCTIVE LUNG DISEASES (COPD) DR. MÁRTA BALASKÓ, associate professor Department of Pathophysiology and Gerontology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 100 Prerequisites: OAA-BK2 completed + OAA-EL2 completed + OAP-KO1 parallel Topic Chronic obstructive lung diseases (COPD) are among the leading causes of mortality in our society. The aim of the course is to analyse the epidemiology, pathogenesis and consequences of the diseases that belong to COPD with regard to the latest scientific evidence. Topics of the course include the pathophysiology of smoking and its consequences, the theoretical basis of the prevention and therapy of bronchial asthma, chronic bronchitis and emphysema. Participants of the course will take an active part in lung function tests in the Laboratory of Respiratory Physiology and gain practical insight in the functional diagnostics of COPD. Theory will be complemented by case histories. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams The final test may be taken repeatedly (twice) to improve final grade. Making up for missed classes An essay on the topic of the missed lecture. Reading material - Obligatory literature - Literature developed by the Department Lecture slides are uploaded to CooSpace. - Notes - Recommended literature Harrison: The Principles of Internal Medicine, 16th edition, (respective chapters), McGraw-Hill 2005 ISBN 0071391428 Lectures 1 2 3 4 5 6 7 8 9 10 Definition of chronic obstructive pulmonary diseases. Epidemiology of COPD. Systemic inflammation in COPD. Dr. Balaskó Márta Pathophysiological consequences of smoking/tobacco use. Dr. Balaskó Márta Case history. Chronic bronchitis: etiology, pathogenesis, and complications. I Dr. Balaskó Márta Chronic bronchitis: etiology, pathogenesis, and complications. II Dr. Balaskó Márta Emphysema: etiology, pathogenesis, and complications I Dr. Balaskó Márta Emphysema: etiology, pathogenesis, and complications II. Case history. Dr. Balaskó Márta Established drugs in the therapy of COPD. Dr. Balaskó Márta New directions in the therapy of COPD. Differential diagnosis of COPD. Dr. Balaskó Márta Etiology and pathogenesis of bronchial asthma I Dr. Balaskó Márta Etiology and pathogenesis of bronchial asthma II. Case history. Dr. Balaskó Márta 245 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 Pathophysiological concepts of asthma treatment. I. Dr. Balaskó Márta Pathophysiological concepts of asthma treatment II. New directions of drug development. Dr. Balaskó Márta Specific spirometric features of different types of COPD. Discussion of case histories. Dr. Balaskó Márta Test. Discussion of results. Dr. Balaskó Márta Practices Seminars Exam topics/questions The definition and epidemiological features of COPD Etiology and pathogenesis of chronic bronchitis Lung function tests and other diagnostic criteria of chronic bronchitis Complications of chronic bronchitis Pathophysiological basis of the treatment of chronic bronchitis Etiology, pathogenesis and complications of emphysema The pathophysiology of smoking The definition and epidemiological features of bronchial asthma Etiology and pathogenesis of bronchial asthma Lung function tests and other diagnostic criteria of bronchial asthma Complications of bronchial asthma Pathophysiological concept of the treatment of bronchial asthma The grade depends on the test score. Participants 246 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-IM1 IMMUNPATHOLOGY 1 DR. PÉTER NÉMETH, professor Department of Immunology and Biotechnology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 300 Prerequisites: OAA-IMM completed + OAP-PA1 parallel Topic Introduction to the pathological background of immune related diseases. Interactive discussions on the basic mechanisms of autoimmune diseases, acquired or heredited immunodeficiencies, tumor immunology, immunological problems of organ transplantations. Clinicopathological analysis of different immunoregulatory failures. Overview of the present biotherapies and the future perceptiveness from the therapeutical monoclonal antibodies to the tumor vaccines. Conditions for acceptance of the semester Active presence on the lectures. Maximum absence 4 hours. Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes See the www.immbio.hu web site during the semester. - Recommended literature Abul K. Abbas: Cellular and Molecular Immunology Janis Kuby: Immunology Jan Klein: Immunology Lectures 0 0 0 0 0 0 0 0 0 0 0 0 Targeting type immune reactions against well conserved antigens Dr. Németh Péter Basic mechanisms of the autoimmune diseases Dr. Németh Péter Physiological autoimmunity Dr. Németh Péter Immunosuppression on autoimmune diseases Dr. Németh Péter Systemic autoimmune diseases Dr. Németh Péter Autoimmune steady state Dr. Németh Péter Organ specific autoimmune diseases Dr. Németh Péter Immunological tolerance Dr. Németh Péter Non-specific and antigens specific immunosuppression for protection of grafted tissues Dr. Németh Péter Failures of the immunological tolerance Dr. Németh Péter Role of genetically conserved antigens under physiological conditions Dr. Németh Péter Natural antibodies in pathological immune regulation Dr. Németh Péter 247 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Allergic reactions in health and diseases Dr. Németh Péter Immunological aspects or organ transplantation Dr. Németh Péter Medical biotechnological perspectives on immunotherapies Dr. Németh Péter Basic mechanism of hypersensitive reactions Dr. Németh Péter Main trends in the immunological laboratory diagnostics Dr. Németh Péter Heredited and acquired immunodefficiencies Dr. Németh Péter Tumor escape Dr. Németh Péter Hypersensitive immunereactions as immunopathological background of different diseases Dr. Németh Péter Delayed type hypersensitivity in chronic inflammatory diseases Dr. Németh Péter Immunity against tumors Dr. Németh Péter Biotherapies in malignant diseases Dr. Németh Péter Tumor vaccines Dr. Németh Péter Pathological autoimmunity Dr. Németh Péter Biotherapies of autoimmune diseases Dr. Németh Péter Natural antibodies in physiological immune regulation Dr. Németh Péter Problems of the vaccine development in HIV infection Dr. Németh Péter Practices Seminars Exam topics/questions See the www.immbio.hu web site before 4 weeks of exam period. Participants 248 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-IMG IMMUNOLOGICAL TECHNIQUES IN LABORATORY PRACTICE DR. DIÁNA SIMON, assistant professor Department of Immunology and Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 10 lectures + 4 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 20 Prerequisites: OAA-IMM completed Topic Demonstration of the general and specific characteristics of immunological methods used in routine clinical laboratory practice and research highlighting their indications and limitations. Practical demonstration of the most important immunoserological and cellular immunological techniques. Role of the immunological methods in research, diagnostics and therapy. Establishment of theoretical and practical laboratory diagnostic background for preclinical and clinical courses. Topics: 1. Characteristics of immunological laboratory diagnostic methods 2. Principals of immunoserological techniques. Precipitation and agglutination based methods, ELISA, RIA, FIA, dot blot, immunoblot techniques. 3. Isolation and light microscopy based investigation of blood and other body fluids 4. Immunocytochemistry 5. Immunohistochemistry 6. Flow cytometry I 7. Flow cytometry II 8. Cell and tissue culture based immunological investigations 9. Methods of HLA typing 10. Diagnostics of systemic autoimmune diseases 11. Diagnostics of organ specific autoimmune diseases 12. Application of monoclonal antibody based therapy 13. Immunotherapies of tumors 14. Diagnostics of immunodeficiencies Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes Individual preparation. Reading material - Obligatory literature - Literature developed by the Department www.immbio.hu - Notes - Recommended literature Abul K. Abbas: Cellular and Molecular Immunology Lectures 1 2 3 4 5 Characteristics of immunological laboratory diagnostic methods Dr. Berki Timea Immunoserology Dr. Berki Timea Cellular immunological methods Dr. Berki Timea Flow cytometry Dr. Berki Timea Diagnostics of systemic autoimmune diseases Dr. Simon Diána 249 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 6 7 8 9 10 Diagnostics of organ specific autoimmune diseases Dr. Simon Diána HLA typing Dr. Simon Diána Monoclonal antibody based therapy Dr. Simon Diána Potentials in immunotherapies of tumors Dr. Berki Timea Diagnostics of immunodeficiencies Dr. Berki Timea Practices 1 2 3 4 Immunserology I-II Cellular immunological methods, Flow cytometry Immunocytochemistry, Immunohistochemistry Vaccine designing Seminars Exam topics/questions Participants Dr. Berki Timea (BETMABO.PTE), Dr. Simon Diána (SIDFABO.PTE) 250 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-KK1 CLINICAL PATHOPHYSIOLOGY 1 DR. MIKLÓS SZÉKELY, professor emeritus Department of Pathophysiology and Gerontology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAP-KO1 parallel Topic The task is to apply the information from pathophysiology in clinical practice. The pathophysiological backgrounds of clinical disorders of cardiovascular, respiratory, hematological or renal origin are to be analyzed. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department Most lectures will appear in CooSpace by the end of the semester. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 COPD, Bronchial asthma Dr. Balaskó Márta Chronic heart failure, basic ways of therapy Dr. Halmosi Róbert Clinical interpretation of ECG Dr. Czopf László József Angina pectoris, basic forms of therapy Dr. Tóth Kálmán Cerebrovascular disorders Dr. Szapáry László Endothel, renin-angiotensin, blood pressure Dr. Kovács Tibor József Pulmonary embolism Dr. Sárosi István Respiratory Failure Dr. Ruzsics István From hypertension to end-stage renal failure Dr. Kovács Tibor József Sleep-apnea syndrome Dr. Faludi Béla Electrolyte- and pH-disorders in the intensive care Dr. Bogár Lajos Proteinuria and its interpretation Dr. Kelényi Gáborné Granulocyte disorders Dr. Balaskó Márta Test Dr. Székely Miklós 251 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions Test-exam Participants 252 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-TD3 STUDENT PROJECT RESEARCH 3 DR. PÉTER BALOGH, associate professor Undergraduate Research Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ both semesters semester ▪ recommended semester: 5 Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours Course headcount limitations (min.-max.): 1 – 300 Prerequisites: OAF-TD2 completed Topic The aim of this subject is to nurture and promote the activity of students sufficiently motivated to perform biomedical project research. The students may progressively enrol to four parts in four separate semesters, for the total credit value of 8. For acknowledging the 3rd and 4th (elective) parts, the student must train research student novice(s). In case of changing the place of work, the subject series can not be re-started. The subject’s administrator is the actual Chairman of the Students’ Research Society (SRS) of the Faculty of Medicine. Conditions for acceptance of the semester To enrol this course a registered SRS membership and completion of Student Project Research 1/2 are mandatory. Acknowledging the course requires first-author presentation of work at a Students’ conference (UP or elsewhere) or Dean’s assay, or presentation at any professional conference relevant to the research field. Grades will be accorded corresponding to the criteria set out in the Rules and Regulations of SRS. For detailed requirements please read the following document: http://aok.pte.hu/run/download2.php?idf=11791&nyelv=eng Mid-term exams Making up for missed classes Not applicable Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Not applicable Lectures Practices 1-24 Research Seminars Exam topics/questions Not applicable Participants Dr. Balogh Péter (BAPOAGP.PTE) 253 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-DIM IMMUNOLOGY OF THE SKIN DR. DIÁNA SIMON, assistant professor Department of Immunology and Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 5 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 100 Prerequisites: OAA-IMM completed Topic Immunology of the skin S.A.L.T. Skin associated lymphatic tissue. Tight networks of cells and diverse pathways of signaling molecules regulating this system. In the recent years new findings, concepts and applications raised the need and importance of a course which is discussing the immune system of the skin. During this course, cellular and molecular organization together with the dissection of the molecular pathways and epigenetic elements regulating the homeostasis and the development of the S.A.L.T. will be presented. Demonstrating the activatory and tolerogenic functions - in the case of inflammation and microbiota - and the discussion of autoimmune skin diseases focusing on Scleroderma, Psoriasis, PLE will also be incorporated. Introduction of hypoxia, allergy and tumor immunology related to the skin and the representation of up to date in vitro experimental techniques and biotechnological applications in the field of skin related research will be demonstrated as well. Topics: 1. Cellular elements of the skin associated lymphatic tissue. 2. Interaction between microbiota (bacterial, fungal, viral) and the immune system 3. Characterization of the Langerhans cell network 4. Cellular and molecular elements during inflammation in the skin 5. Cellular and molecular elements during inflammation in the skin 6. Dissection of the molecular pathways and epigenetic elements regulating the homeostasis and the development of the S.A.L.T. 7. Introduction of hypoxia in the immune system of the skin 8. Cellular and molecular participants in the tumor immunology of the skin 9. Immunological mechanisms behind wound healing 10. Fundamentals of allergy in the skin 11. Cellular and molecular dissection of the pathogenesis and maintenance of Scleroderma 12. Cellular and molecular dissection of the pathogenesis and maintenance of Psoriasis and PLE 13. Presentation of up to date in vitro techniques in the field of skin related research including in vitro generation of immune cells from progenitors; coculture assays; 3D tissue cultures; primary fibroblast isolation etc. 14. Tissue reconstruction techniques: autologous tissue transplantation and cutting edge artificial skin constructs Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes Individual preparation. Reading material - Obligatory literature - Literature developed by the Department www.immbio.hu - Notes - Recommended literature Lectures 1 2 3 S.A.L.T. Dr. Simon Diána Immunological relevance of the microbial community of the skin Dr. Simon Diána Langerhans cell network in the skin Dr. Simon Diána 254 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 4 5 6 7 8 9 10 11 12 13 14 Inflammation in the skin I Dr. Simon Diána Inflammation in the skin II Dr. Simon Diána Signaling in the skin Dr. Simon Diána Hypoxia in the skin Dr. Najbauer József Tumor immunology of the skin Dr. Najbauer József Immunological mechanisms behind wound healing Dr. Simon Diána Allergy Dr. Berki Timea Scleroderma Dr. Simon Diána Psoriasis, Polymorphic light eruption (PLE) Dr. Simon Diána In vitro experimental techniques Dr. Simon Diána Autologous tissue transplantation, Artificial skin Dr. Simon Diána Practices Seminars Exam topics/questions Participants 255 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EAF DEVELOPMENT AND MALFORMATIONS OF THE HUMAN CEREBRAL CORTEX DR. HAJNALKA GABRIELLA ÁBRAHÁM, associate professor Central Electron Microscope Laboratory Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OAA-NEA completed Topic Pre- and postnatal human cortical development is an essential event of the development of central nervous system, which is not discussed in details in embryology. The growing information about cortical development available nowadays gives reason for its review in the medical curriculum. Disturbances of cortical development e.g. altered neuronal migration are in the background of several diseases of the pediatrics, neurology and psychiatry. We discuss in details the normal human pre- and postnatal cortical development, the neuronal migration and its alterations as the most common cause of developmental malformations of the nervous system. Students are going to hear about the molecular, genetical and pathological background of these diseases, extending the knowledge that is given by pathology and providing basis for the future clinical subjects. Disruption of cortical development after premature birth and in human trisomies (Down, Edwards, Patau syndrome) will also be introduced. Conditions for acceptance of the semester Participation in 80% of the lectures is obligatory. On the 5th week and at the end of course test going to be written. Achievement of 50% on the tests is needed for the credit. Mid-term exams Making up for missed classes Uncertified absences must not exceed 2 hours. There is no possibility for making up of missed lectures. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Kandel, Schwartz and Jessel: „Principles of Neural Sciences”, chapters dealing with the development of the cortex. The purchase of the book is not needed, we provide the copy of the relevant chapters, or relevant articles. Lectures 1 2 3 4 5 6 7 8 9 10 11 Histological structure and function of neocortex and archicortex. Dr. Ábrahám Hajnalka Gabriella Phases of the human cortical development. Structure of the developing cortex. Dr. Ábrahám Hajnalka Gabriella Places of cell proliferation. (Germinal matrix). Proliferation of pyramidal cells, interneurons and glial cells. Dr. Seress László Antal Neurogenesis after birth in the rodent, primate and human cortex. Dr. Seress László Antal Forms of neuronal migration. Dr. Ábrahám Hajnalka Gabriella Factors guiding neuronal migration. Dr. Ábrahám Hajnalka Gabriella Types of neurons and synapses. Neuronal maturation and differentiation. Dr. Seress László Antal Myelin formation in the cortex. Dr. Seress László Antal Postnatal cell proliferation in prematurely born infants. Dr. Ábrahám Hajnalka Gabriella Postnatal neuronal differentiation in prematurely born infants. Dr. Ábrahám Hajnalka Gabriella Consequences of failures of neuronal proliferation and migration. Lyssencephaly. Dr. Ábrahám Hajnalka Gabriella 256 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 Consequences of failures of neuronal proliferation and migration. Polymicrogyria, epilepsy, schizophrenia. Dr. Ábrahám Hajnalka Gabriella Cortical developmental malformations in trisomies. (Down’s, Edwards’, Patau’s syndromes). Dr. Ábrahám Hajnalka Gabriella Test Dr. Ábrahám Hajnalka Gabriella Practices Seminars Exam topics/questions Questions of the test are based on these themes. 1. Structure of neocortex and archicortex. 2. Differences in the function of neocortex and archicortex. 3. Phases of the human cortical development. 4. Histological structure of the developing cortex. 5. Germinal matrices. 6. Methods used to detect cell proliferation. 7. Proliferation of pyramidal cells, interneurons and glial cells. 8. Neurogenesis after birth in the human brain. 9. Forms of neuronal migration during cortical development. 10. Factors guiding neuronal migration. 11. Differentiation, maturation of neurons. Formation of synapses. 12. Postnatal cell proliferation. 13. Cortical alterations in prematurely born infants. 14. Myelin formation in the developing human cortex. 15. Consequences of failures of neuronal proliferation and migration. Lyssencephaly, polymicrogyria, epilepsy, schizofrenia etc. 16. Cortical developmental malformations in trisomies. (Down’s, Edwards’, Patau’s syndromes). Participants Dr. Ábrahám Hajnalka Gabriella (ABHMAAO.PTE), Dr. Seress László Antal (SELMAAO.PTE) 257 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EVO EVOLUTIONARY IMMUNOBIOLOGY DR. PÉTER ANDRÁS ENGELMANN, associate professor Department of Immunology and Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 30 Prerequisites: OAA-MB2 completed + OAA-IMM completed Topic The course describes the molecular and cellular elements of innate/adaptive immunity in their evolutionary contexts. Moreover, it discusses the ancient immune functions (phagocytosis, antimicrobial molecules, antiviral RNA interference) along with the newest research data about the development of adaptive immunity. Conditions for acceptance of the semester Referral, max. 2 absences from the seminars Mid-term exams presentation/referral from chosen topic Making up for missed classes Individual preparation Reading material - Obligatory literature - Literature developed by the Department www.immbio.hu - Notes - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Definition of the topics and course, comparison of innate and adaptive immunity Pattern recognition receptors: Toll, Croquemort and others Conserved signal transduction pathways in immunology Cellular immune functions of innate immunity: phagocytosis, cytotoxicity, encapsulation-, capsule-, granulomeformation Humoral immune components I: antimicrobial molecules, peptides. Prophenoloxidase cascade, coagulation. Humoral immune components II: Acute-phase proteins, complement-evolution Humoral immune components III: evolution of cytokines and chemokines Sounds of Silence or the role of RNA interference (RNAi) in innate immunity, antiviral innate immunity Alternative adaptive immunity in invertebrates and in ancient vertebrates? Histoincompatibility in invertebrates, MHC-evolution Immunological twilight-zone - The appearance of adaptive immunity, immunological triumvirate RAG-time: immunglobulin, TCR development in the context of phylogenesis Phylogenetical development of vertebrate immune organs Host-pathogen co-evolution Exam topics/questions Participants Dr. Engelmann Péter András (ENPAAA.T.JPTE), Dr. Németh Péter (NEPGAAO.PTE) 258 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-GMK QUALITATIVE AND QUANTITATIVE ANALYSIS OF DRUGS FROM HUMAN TISSUE DR. ÁGNES FARKAS, associate professor Department of Pharmacognosy Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 50 Prerequisites: no prerequisites Topic The course provides knowledge about the traceability of active pharmaceutical ingredients in various biological matrices. It discusses sampling of biological matrices, sample preparation (extraction) methods [LLE, SPE, SPEC, SPME, MEPS], and various chromatographic analyzes [TLC, GC, LC] as well. The announced theme of the course is to present the CNS effects of active pharmaceutical ingredients, as well as drugs in the official investigation. The sampling procedures and techniques are presented, as well as their official confidence circumstances. The appearance of drug compounds and drugs in biological matrices, and their pharmacokinetic properties are discussed, as well as traceability of live and corpse biological matrices (blood, urine, hair, nails, saliva, or liver, kidney, brain, or cerebrospinal fluid. After proper selection of analytical tests, the requirements set for a variety of measuring instruments will be discussed. Standard evaluation and communication, as well as the laws and regulations in force in the analytical results complete the course topics. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams According to the Code of Studies and Examinations Making up for missed classes According to the Code of Studies and Examinations Reading material - Obligatory literature R.C. Baselt: Disposition of Toxic Drugs and Chemicals in Man, 6th ed., Biomedical Publications, Foster City, CA, 2002 A.C. Moffat, M.D. Osselton, B. Widdop: Clarke’s Analysis of Drugs and Poisons, Pharmaceutical Press, London, 2004. - Literature developed by the Department - Notes - Recommended literature R.J. Flanagan, A. Taylor, I.D. Watson, R. Whelpton: Fundamentals of Analytical Toxicology, John Wiley & Sons, Hoboken, NJ, 2007. Lectures 1 2 3 4 5 6 7 8 Introduction to Toxicology. Categorization of Toxins I Dr. Benkő András Antal Introduction to Toxicology. Categorization of Toxins II Dr. Benkő András Antal Poisons Effect of the Living Body I Dr. Benkő András Antal Poisons Effect of the Living Body II Dr. Benkő András Antal Investigation of the Forensic Laboratories. Sampling rules. I Dr. Benkő András Antal Investigation of the Forensic Laboratories. Sampling rules. II Dr. Benkő András Antal Investigation of Non-standard Human Tissues I Dr. Benkő András Antal Investigation of Non-standard Human Tissues II Dr. Benkő András Antal 259 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Biological Materials Preparation. Extraction Procedures I Dr. Benkő András Antal Biological Materials Preparation. Extraction Procedures II Dr. Benkő András Antal Forensic Toxicological Investigation of the Human Samples by Chromatogaphy I Dr. Benkő András Antal Forensic Toxicological Investigation of the Human Samples by Chromatogaphy II Dr. Benkő András Antal Criteria and Evaluation. Expert Opinion in the Forensic Toxicology I Dr. Benkő András Antal Criteria and Evaluation. Expert Opinion in the Forensic Toxicology II Dr. Benkő András Antal Natural Cannabioids (marihuana, hasis, and hasis oil) I Dr. Benkő András Antal Natural Cannabioids (marihuana, hasis, and hasis oil) II Dr. Benkő András Antal Synthetic Cannabino-mimetics (spice, pot-puri, herbal, bio-grass, K2) I Dr. Benkő András Antal Synthetic Cannabino-mimetics (spice, pot-puri, herbal, bio-grass, K2) II Dr. Benkő András Antal First Generation of Amphetamines (ecstasy, speed) Dr. Benkő András Antal Second generation of disco drugs (catinon and derivatives) Dr. Benkő András Antal Opiates (morphine, codeine, heroine) I Dr. Benkő András Antal Opiates (morphine, codeine, heroine) II Dr. Benkő András Antal Cocaine Dr. Benkő András Antal Body-pack Syndroma. Dr. Benkő András Antal Final Student ppt Presentation I Dr. Benkő András Antal Final Student ppt Presentation II Dr. Benkő András Antal Final Student ppt Presentation III Dr. Benkő András Antal Final Student ppt Presentation IV Dr. Benkő András Antal Practices Seminars Exam topics/questions 10 min ppt presentation from the international forensic sci article Participants 260 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-HIF THE ANATOMY, PHYSIOLOGY, DEVELOPMENT FORMATION AND PATHOLOGY OF THE HIPPOCAMPAL DR. LÁSZLÓ SERESS, professor Central Electron Microscope Laboratory Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAA-NEA completed + OAA-EL2 completed Topic It is known that the normal function of the hippocampal formation is strongly connected with the memory formation. The pathology of this brain structure is known in illnesses that affects a large population, such as epilepsy or Alzheimer’s disease. The aim is to discuss in details the structure, connectivity, physiology and pathology of the hippocampal formation and that of the memory-related archicortical areas. In addition, we give a general description of the ontogenetic development and ageing of the hippocampus in humans as well as discuss the recently popular ideas of stem-cell hypothesis and neuronal repair in the adult brain. Conditions for acceptance of the semester Written test and no more than 3 absences. Mid-term exams Making up for missed classes No possibility Reading material - Obligatory literature - Literature developed by the Department Kandel, Schwartz, Jessel: Principles of Neuronal Sciences We provide xerox-copies of the necessary literature - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Methods to study cell formation in the young and adult hippocampus Dr. Seress László Antal The anatomy of the rodent archicortex Dr. Seress László Antal The anatomy of the human archicortex Dr. Seress László Antal Neuronal types of the dentate gyrus Dr. Seress László Antal Connectivity among the dentate neurons Dr. Seress László Antal Neuronal types of Ammon’s horn in rodents and primates Dr. Seress László Antal Afferent and efferent connections of Ammon’s horn Dr. Seress László Antal Neuronal cell formation and development of the rodent hippocampus Dr. Seress László Antal Neuronal cell formation and development of the human hippocampus Dr. Ábrahám Hajnalka Gabriella Stem cell theory Dr. Seress László Antal Adult neuronal cell formation in the human dentate gyrus Dr. Seress László Antal Hippocampal dependent memory in rodents Dr. Seress László Antal 261 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Methods to study hippocampal dependent memories Dr. Seress László Antal Hippocampal dependent memory in monkeys Dr. Seress László Antal Hippocampal dependent memories in humans Dr. Seress László Antal Hippocampal memory in ageing Dr. Seress László Antal Postnatal development of memory function in children Dr. Seress László Antal Neuropathology of epilepsy Dr. Ábrahám Hajnalka Gabriella Neuropathology of epilepsy Dr. Ábrahám Hajnalka Gabriella Neuropathology of Alzheimer disease Dr. Seress László Antal Neuropathology of Alzheimer disease Dr. Seress László Antal Experimental methods to study connectivity among limbic structures Dr. Ábrahám Hajnalka Gabriella Electronmicroscopy of the epileptic dentate gyrus Dr. Ábrahám Hajnalka Gabriella Normal electronmicroscopy of the dentate gyrus Dr. Seress László Antal Experimental models of epilepsy Dr. Seress László Antal Experimental models of epilepsy Dr. Seress László Antal Neuronal cell formation in epilepsy and in adulthood Dr. Seress László Antal Exam Dr. Seress László Antal Practices Seminars Exam topics/questions At the end of the course every student has to fill a test with 5 questions that will involve 5 different subjects discussed during the lectures. Each question can be answered with a short description. The final note depends on the number of correctly answered questions. As an example: „Describe the neuronal circuits and their postnatal development between the excitatory neurons of the hippocampal dentate gyrus”. Participants Dr. Ábrahám Hajnalka Gabriella (ABHMAAO.PTE), Dr. Seress László Antal (SELMAAO.PTE) 262 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-KUO MEDICAL HUMANITIES DR. TAMÁS MOLNÁR F., professor Department of Operational Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 100 Prerequisites: OAA-AA2 completed + OAA-EL2 completed Topic This interactive course is created to III.-IV. graders who has General Medicine, Dentistry or Pharmacy Major. Its lecturers are medical practitioners, who are all well-known and respected in their fields of medical practice. They all believe that the humanities play an important role in becoming a better doctor. The emphasis is, of course, on the medical aspects of the subjects, the arts and humanities parts are complementary information. The subject is a balanced combination of the applied history of medicine, cultural history, art history and philosophy - with the admitted intention to create strong basis for students in critical and human-focused approaching of modern, evidence-based medicine. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department Teaching materials of the course (from the instructors). - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 The summary of the subject and its relevance in the medical curriculum. C P Snow: The Two Cultures - theory Dr. Molnár F. Tamás The benefits, the usage and the risks of the History of Medicine and the Medical Humanities. Dr. Molnár F. Tamás Diseases, therapy and literature. Tuberculosis the white death Dr. Molnár F. Tamás Diseases and therapy - reflections. Asthma and allergy Dr. Molnár F. Tamás COPD and pathographies of cardiopulmonary Dr. Molnár F. Tamás Neuroendocrine tumors: Cushing to Kulchitsky Dr. Molnár F. Tamás Orto-rhino-laryngology patographies in Medical Humanities aspect Dr. Gerlinger Imre Medical Humanistic approach of Surgery Dr. Molnár F. Tamás Genetics - the history behind the story Dr. Hoffmann Gyula Forensics Medicine: literature, film and the modern media - the history behind the stories Dr. Molnár F. Tamás Infectious diseases and epidemics - their historical aspects and literary reflections (D. Defoe: A Journal of the Plaque Year) Dr. Molnár F. Tamás Cultural aspects of addictology - alcohol, nicotine, drugs and addicts Dr. Molnár F. Tamás Surgery of Penetrating Trauma of Chest Cavities – it’s past, present and the arts (St Sebastian) Dr. Molnár F. Tamás Oncology (W. H. Auden: Miss Gee, A. Solzhenitsyn: Cancer Ward , J. Updike) Dr. Molnár F. Tamás 263 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 15 16 17 18 19 20 21 22 23 24 25 26 27 28 The Bible and medical treatment - Old Testament/New Testament Dr. Molnár F. Tamás The metamorphosis of the concept of health and illness: from the Ten Plaques of Egypt to the Purification through Suffering. The death - Thanatos, Styx Dr. Molnár F. Tamás Saints, Christian Church and disease - Patron Saints Dr. Molnár F. Tamás Graeco-Roman mythology and medicine - the frame of the mythology Dr. Molnár F. Tamás Syndromes: names, stories and medicine (Münchausen to Pickwick) Dr. Molnár F. Tamás Social traumatology: the Trianon Syndrome Dr. Molnár F. Tamás Anaesthesia, Intensive therapy - lessons learnt from history Dr. Rendeki Szilárd The relation of literature to illnesses (s. Sonntag: Illness as a Metaphore) Dr. Molnár F. Tamás Writers, poets, doctors and illnesses (Moliére, Shakespeare, Ibsen) Dr. Molnár F. Tamás Social Sciences and Medicine (Foucault) Dr. Molnár F. Tamás Visual Arts and Anatomy Dr. Reglődi Dóra Visual Arts and Clinical Medicine Dr. Molnár F. Tamás „How can I tell you?” - the communicative strategies of a cultured MD about diagnose and prognosis. The acceptance of the unacceptable - and the bearer of bad news Dr. Bogár Lajos Patient and Doctor. Inside out. Dr. Molnár F. Tamás Practices Seminars Exam topics/questions Grades will be based on the lectures and the recommended readings. Participants 264 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MME MOLECULAR MEDICINE DR. JUDIT PONGRÁCZ, professor Department of Pharmaceutical Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 150 Prerequisites: no prerequisites Topic Introduction into molecular medicine Conditions for acceptance of the semester According to the Code of Studies and Examinations Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes www.medbiotech.com - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction into molecular medicine Dr. Pongrácz Judit The genome Dr. Pongrácz Judit Sequencing of the genome Dr. Pongrácz Judit Investigation of the human genome with microarrays Dr. Pongrácz Judit Genes and diseases Dr. Pongrácz Judit Nuclear receptors Dr. Pongrácz Judit Personalized genetics Dr. Pongrácz Judit Immunodeficiencies Dr. Pongrácz Judit Cancers (introduction) Dr. Pongrácz Judit Molecular mechanisms of cancer development Dr. Pongrácz Judit Obesity: introduction Dr. Pongrácz Judit Genomics of obesity Dr. Pongrácz Judit Genes involved in development of obesity Dr. Pongrácz Judit Therapeutic approaches to obesity. Interconnected mechanisms in lipid metabolism Dr. Pongrácz Judit 265 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions www.medbiotech.com Participants 266 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MOD MOLECULAR DIAGNOSTICS DR. JUDIT PONGRÁCZ, professor Department of Pharmaceutical Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 150 Prerequisites: no prerequisites Topic Structure of a molecular genetic laboratory, working areas, special devices and instrumentation. Biological information. Conditions for acceptance of the semester According to the Code of Studies and Examinations Mid-term exams Making up for missed classes According to the Code of Studies and Examinations Reading material - Obligatory literature - Literature developed by the Department - Notes www.medbiotech.com - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Structure of a molecular genetic laboratory, working areas, special devices and instrumentation. Biological information. Dr. Pongrácz Judit Mutations, polymorphisms. The genetic code. Dr. Pongrácz Judit Mutations, polymorphisms. The genetic code. Dr. Pongrácz Judit Special mutation consequences. Dr. Pongrácz Judit Dynamic mutations. Dr. Pongrácz Judit Mendelian inheritance. Dr. Pongrácz Judit Multifactorial diseases. Dr. Pongrácz Judit Examples for monogenic diseases. Dr. Pongrácz Judit Examples for monogenic diseases. Dr. Pongrácz Judit Examples for monogenic diseases. Dr. Pongrácz Judit Pharmacogenetics. Dr. Pongrácz Judit Molecular testing in oncology. Dr. Pongrácz Judit Methodology of the molecular diagnostic procedures. Dr. Pongrácz Judit Methodology of the molecular diagnostic procedures. Dr. Pongrácz Judit 267 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions www.medbiotech.com Participants 268 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MOT MOLECULAR THERAPIES DR. JUDIT PONGRÁCZ, professor Department of Pharmaceutical Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 150 Prerequisites: no prerequisites Topic Gene therapy, in vivo gene therapy Conditions for acceptance of the semester According to the Code of Studies and Examinations Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes www.medbiotech.com - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Functional genomics I Dr. Pongrácz Judit Functional genomics II Dr. Pongrácz Judit Recombinant protein expression Dr. Pongrácz Judit Gene therapy, in vivo gene therapy Dr. Pongrácz Judit Ex vivo gene therapy, Therapies based on protein replacement I Dr. Pongrácz Judit Therapies based on protein replacement II Dr. Pongrácz Judit Recombinant antibodies and phage phage display technique Dr. Pongrácz Judit Anti-cytokine therapy (Sepsis) Dr. Pongrácz Judit Transgene technology and mouse models in modern biological research Dr. Pongrácz Judit Embryonic and adult stem cells for regenerative medicine I Dr. Pongrácz Judit Embryonic and adult stem cells for regenerative medicine II Dr. Pongrácz Judit Cell cycle and cancer therapy, p53 I Dr. Pongrácz Judit Cell cycle and cancer therapy, p53 II Dr. Pongrácz Judit Gene silencing technologies Dr. Pongrácz Judit 269 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions www.medbiotech.com Participants 270 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-N27 CLINICAL HUNGARIAN 1 DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 5 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OAE-H4A completed Topic The aim of the course is to help foreign students of the English Programme survive during their clinical studies in Hungary through developing appropriate language competencies and also widen the scope of existing competencies in the field of doctor-patient communication. At present teaching in Medical Hungarian is provided in the first 4 semesters when students do not participate in clinical studies. Therefore this course offered for the fifth and sixth semesters to enable students to cope with language, tasks in their clinical studies. Conditions for acceptance of the semester Participation in practicles is obligatory. Absences exceeding 15% but below 25% of the total number of contact hours can be excused by the group tutor. In case absences exceed 25% of the total number of contact hours the course must be regarded as uncompleted. Mid-term exams Making up for missed classes To be discussed with the course tutor in each individual case. Reading material - Obligatory literature - Literature developed by the Department Mária Győrffy: English for Doctors, Idióma Bt., Pécs 2001 – can be purchased in the Department - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 Ismétlés - Revision Ismétlés - Revision Magas vérnyomás, gyomorvérzés, epehólyag műtét - High blood pressure, bleeding in the stomach, cholecystectomy Magas vérnyomás, gyomorvérzés, epehólyag műtét - High blood pressure, bleeding in the stomach, cholecystectomy Mellkasi fájdalom, székelési panaszok - Chest pain, complaints on defecation Mellkasi fájdalom, székelési panaszok - Chest pain, complaints on defecation Vizelési problémák, transzfúzió szív-és érrendszeri betegségek - Problems on urination, blood transfusion, Cardiovascular problems Vizelési problémák, transzfúzió szív-és érrendszeri betegségek - Problems on urination, blood transfusion, Cardiovascular problems Pajzsmirigy túlműködés, hasnyálmirigygyulladás - Hyperthyroidism, pancreatitis Pajzsmirigy túlműködés, hasnyálmirigygyulladás - Hyperthyroidism, pancreatitis Betegeknek szóló utasítások - Giving instructions to patients Betegeknek szóló utasítások - Giving instructions to patients Vakbélgyulladás, végbéldaganat, bélelzáródás - Appandicitis, rectal tumour, intestinal obstruction Vakbélgyulladás, végbéldaganat, bélelzáródás - Appandicitis, rectal tumour, intestinal obstruction Nyelőcsődaganat, gyomorfekély, epehólyaggyulladás - Oesophageal tumour, gastric ulcer, cholecystitis Nyelőcsődaganat, gyomorfekély, epehólyaggyulladás - Oesophageal tumour, gastric ulcer, cholecystitis Sérvek, visszér, trombózis - Hernias, varicose veins, thrombosis Sérvek, visszér, trombózis - Hernias, varicose veins, thrombosis Epeköves görcs, gyomordaganat - Cholelithasis, gastric cancer Epeköves görcs, gyomordaganat - Cholelithasis, gastric cancer Aranyérbeteség, lágyéksérv - Haemorrhoids, inguinal hernia Aranyérbeteség, lágyéksérv - Haemorrhoids, inguinal hernia 271 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 23 24 25 26 27 28 Gyógyszerfajták, gyógyszerfelírás, gyógyszerártalom - Types of medications, prescribing medicatons based on patient complaints,side-effects of drugs Gyógyszerfajták, gyógyszerfelírás, gyógyszerártalom - Types of medications, prescribing medicatons based on patient complaints,side-effects of drugs Balesetek, égési sérülések, törések - Accidents, injuries, fractures Balesetek, égési sérülések, törések - Accidents, injuries, fractures Műtét előtti vizsgálat, altatás előtt és után használt szakkifejezések, értékelés - Patient examnation before an operation, expressions used before and after anaesthesia, evaluation. Műtét előtti vizsgálat, altatás előtt és után használt szakkifejezések, értékelés - Patient examnation before an operation, expressions used before and after anaesthesia, evaluation. Seminars Exam topics/questions Two written tests – 4 oral presentations Participants Dr. Hegedűs Anita (HEAAAA.B.JPTE), Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE), Dr. Warta Vilmos (WAVEAB.B.JPTE), Eklicsné Dr. Lepenye Katalin (EKLAXA.B.JPTE), Hamarné Sávay Judit (HASMAAO.PTE), Hild Gabriella (MAGAAD.B.JPTE), Horváth Lilla Anita (HOLFABP..PTE), Kurdiné Molnár Eszter (KUMPAAK.PTE), Lokodiné Szolcsányi Judit (LOSIAAB.PTE), Mészégetőné Halmos Éva (MEHHABE.PTE), Móriczné Győrffy Mária (MOGPAAP.PTE), Nagy Gabriella (NAGMAAO.PTE), Ronczykné Berta Anikó (BEAAAI.B.JPTE), Szántóné Csongor Alexandra (CSAAAA.B.JPTE), Váradi Katalin (VAKHAAE.PTE) 272 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-NMN NEUROIMAGING METHODS IN NEUROPSYCHOLOGICAL RESEARCH ÁDÁM FELDMANN, assistant lecturer Department of Behavioural Sciences Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 0 lectures + 7 practices + 7 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 10 Prerequisites: no prerequisites Topic The aim of the course is to give an introduction to structural and functional MRI methods in field of neuropsychology. The students will be introduced to methods of fMRI experimental planning and statistical analysis. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes Should be discussed with the course tutor in each individual case. Reading material - Obligatory literature - Literature developed by the Department Materials are available on CooSpace. - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 Functional MRI and sMRI basics, softwares, file formats, data types Experimental planning Preprocessing steps in a single case and multiple case studies using SPM. Functional MRI statistics (individual and group analyses) using SPM. Controlling nuisance variables using SPM. Cognitive functional network analysis using SPM. Test Seminars 1 2 3 4 5 6 7 History of neuroimaging, elements. fMRI and sMRI basics. Experimental design (block design). Advanced experimental design (event-related fMRI). Preprocessing steps and statistical analysis (hypothesis and data-driven methods). Mapping cognitive functional networks and complex studies Summary Exam topics/questions Participants Feldmann Ádám (FEAFAD.B.JPTE) 273 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-PRB PROTEIN BIOTECHNOLOGY DR. JUDIT PONGRÁCZ, professor Department of Pharmaceutical Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 5 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 150 Prerequisites: no prerequisites Topic Biochemical properties of proteins. Protein synthesis. Review of the differences between procaryotic and eucaryotic protein synthesis. Conditions for acceptance of the semester According to the Code of Studies and Examinations Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes www.medbiotech.com - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 Biochemical properties of proteins. Protein synthesis. Review of the differences between procaryotic and eucaryotic protein synthesis. Dr. Pongrácz Judit Protein folding, the formation of 3D structure. Chaperons. Folding problems and folding diseases. Dr. Pongrácz Judit Protein sorting and targeting. Dr. Pongrácz Judit Study of protein structures: X-ray crystallography, NMR, mass spectrometry. Dr. Pongrácz Judit Protein purification (chromatography, electrophoresis) and analysis (SDS-PAGE, 2 dimensional electrophoresis, mass spectrometry). Dr. Pongrácz Judit Posttranslational modification of proteins and their analysis using proteomics methods. Dr. Pongrácz Judit Protein-protein interactions and their analysis: yeast two hybrid system, mass spectrometry, Biacore and other techniques. Dr. Pongrácz Judit Heterologue expression I: Homologue and heterologue expression, biopharming; expression systems, criteria to the selection of expression platforms, heterologue expression in Escherichia coli, formation of inclusion body, periplasmic secretion, formation of disulfide bonds. Dr. Pongrácz Judit Heterologue expression II: The disadvantages of the Escherichia coli system, development of new expression platforms; protein expression in gram-positive bacteria; the Staphylococcus carnosus expression system; Protein expression in yeasts; the Saccharomyces cerevisiae and the Pichia pastoris expression platforms. Dr. Pongrácz Judit Heterologue expression III: The disadvantages of the microbial protein expression; heterologue expression in plant cell cultures, transformation with Agrobacteria, expression in mammalian cell, functionalized cells; heterologue expression in insect cell lines, the baculovirus-insect cell expression system. Dr. Pongrácz Judit Definition of protein engineering; de novo design, artificial growing factors; rational design, site-directed mutagenesis; directed evolution, random mutagenesis, DNA shuffling, exon shuffling. Dr. Pongrácz Judit 274 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 Production of human therapeutic proteins. Biopharmaceuticals, production of human therapeutic proteins; production of insulin, protein engineering of insulin; development of recombinant Hepatitis B vaccine; production of monoclonal antibodies; problems with the storage, in vivo stability and administration of therapeutic proteins. Dr. Pongrácz Judit Production of human therapeutic enzymes: Enzymes in human therapy; production, and human therapeutically application of deoxyribonuclease I, β-glucocerebrosidase, urate oxidase and L-asparaginase, mechanism of action. Dr. Pongrácz Judit Production of diagnostic enzymes. Importance of enzymes in diagnosis, production and application of glucose oxidase, galactose oxidase, cholesterol oxidase and horseradish peroxidase; protein engineering of enzymes. The application of therapeutic proteins. Possible administration, perspectives and future possibilities. The national and international requirements for protein therapeutic products. Dr. Pongrácz Judit Practices Seminars Exam topics/questions www.medbiotech.com Participants 275 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 ATT5 PHYSICAL EDUCATION 5 TAMÁS TÉCZELY, physical education teacher Physical Education and Sportcenter Course director: 0 credit ▪ signature ▪ Criterion requirement module ▪ both semesters semester ▪ recommended semester: 5 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 2 – 50 Prerequisites: ATT4 Topics The main goal of the university’s physical education is the development of our students' health. To prevent injuries, in the introductory part of the sessions warming up of different muscle groups. We are improving the fitness stamina and strength of our students through the sport movements and by using modern training methods. The practice of sport by becoming familiar with the rules of the game. Our task is to incorporate regular physical activity into the lifestyle of the students. Course type: Facultative requirement The goal is that, after fulfilling the four semesters criteria the students of the general medical education, dentists education, pharmacist have the possibility to continue the regular physical activities in organized conditions at the university. PTE Physical Education and Movement Centre organizes, directs and controls the implementation of subject Physical Education 5. The organization, the direction and the control are done by the teachers in charge of the workshops or by persons delegated by the dean of the Medical School We record the presence of the students. We verify the completion of the semester by confirmation of the registration plate in ETR system. Conditions for acceptance of the semester: The minimum requirement for acceptance of the semester is to attend on a ten week session training. During semester 4x45 minutes absence is allowed. Accepting additional 4x45 minutes absence is the competence of the supervisor. Course type: Possible absence: We provide 6x45 minutes as a catching up time, which should be approved by the teacher. The catch up sessions have to be fulfilled during the last three weeks of semester. Practices The selection of the sport movements depends on the chosen game. Exam questions The acceptance of the semester is not connected to exam. PE teachers Farkas György (FAGMAAO.PTE), Finak Gáborné Gombosi Eszter (FIGMAAT.PTE) Lipcsik Zoltán (LIZIAAT.PTE), Németh Attila (NEAGAET.PTE), Dr. Rugási Endre (RUEMAAP.PTE), Téczely Tamás (PETLAAT.PTE) 276 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-ASZ THE ANTIMICROBIAL DRUGS AND THEIR CLINICAL USE DR. BÉLA KOCSIS, associate professor Department of Medical Microbiology and Immunology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 100 Prerequisites: OAP-MI1 completed Topic The aim of these lectures is to give a reliable and detailed knowledge about the antimicrobial drugs and their clinical use; to give ideas how to choose the proper drug for the prophylaxis and therapy of infectious diseases Conditions for acceptance of the semester None Mid-term exams Making up for missed classes None Reading material - Obligatory literature Jawetz et al.: Medical Microbiology - Literature developed by the Department - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Introduction, historical data, basic definitions Dr. Kocsis Béla Characterisation of antimicrobial drugs, chemical structure, their targets Dr. Kocsis Béla Characterisation of antimicrobial drugs, sensitivity and resistance Dr. Kocsis Béla Characterisation of antimicrobial drugs, sensitivity and resistance Dr. Kocsis Béla Pharmacokinetics and pharmacodynamics of anti-infective drugs Dr. Kocsis Béla The antibiotic prophylaxis. Dr. Kocsis Béla The empiric antimicrobial therapy Dr. Kocsis Béla The antimicrobial therapy based on microbiologic result Dr. Kocsis Béla The choice of best antimicrobial drug Dr. Kocsis Béla The reasons of an unsuccessful antimicrobial therapy Dr. Kocsis Béla The antimicrobial drugs in details. The inhibitors of the cell wall biosynthesis Beta-lactams Penicillins Dr. Kocsis Béla Cephalosporins Dr. Kocsis Béla Carbapenems, monobactams, glicopeptides Dr. Kocsis Béla The inhibitors of the protein biosynthesis Aminoglicosides Dr. Kocsis Béla Tetracyclines Chloramphenicol Macrolides Dr. Kocsis Béla 277 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 16 17 18 19 20 21 22 23 24 25 26 27 28 The inhibitors of the nucleic acid biosynthesis Rifampins Sulfonamides Dr. Kocsis Béla Kinolons Fluorokinolons Dr. Kocsis Béla The antimycotic drugs Dr. Kocsis Béla The antimycotic drugs Dr. Kocsis Béla The antiviral drugs Dr. Kocsis Béla The antiviral drugs HIV - AIDS Dr. Kocsis Béla The antiparasitic therapy. The chemoprophylaxis of malaria Dr. Kocsis Béla The antimicrobial therapy of respiratory and urinary tract infections Dr. Kocsis Béla Cardiovascular and wound infections, sepsis Dr. Kocsis Béla Central nervous system, abdominal and enteric infections Dr. Kocsis Béla Antimicrobial therapy of patients under immunosuppression, pregnancy.... Dr. Kocsis Béla The pharmacological aspects of antimicrobial therapy Dr. Kocsis Béla The future of antimicrobial therapy Dr. Kocsis Béla Practices Seminars Exam topics/questions None Participants 278 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-FAJ PAIN AND ANALGESICS DR. GÁBOR PETHŐ, professor Department of Pharmacology and Pharmacotherapy Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours Course headcount limitations (min.-max.): 5 – 50 Prerequisites: OAP-GT1 completed Topic The aim of the course is to give an integrative overview on the physiological, pathophysiological and pharmacological aspects of pain. Major tasks are to (i) provide information on peripheral and central mechanisms of pain and hyperalgesia; (ii) describe the major features of existing analgesics including opioids, non-steroidal antiinflammatory agents and adjuvant analgesics; (iii) outline novel targets for development of analgesic drugs. The course will also help students to prepare for the exams in Pharmacology 2 and 3. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes There is no way to make up for missed lectures. Reading material - Obligatory literature - Literature developed by the Department The material of the lectures is available in PDF format at the Intranet site of the Department of Pharmacology and Pharmacotherapy. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Basic terms related to pain and nociceptors Dr. Pethő Gábor Features of capsaicin-sensitive nociceptors Dr. Pethő Gábor Peripheral mechanisms of hyperalgesia Dr. Pethő Gábor Central mechanisms of hyperalgesia and allodynia Dr. Pethő Gábor Features of neuropathic pain Dr. Pethő Gábor Pharmacology of non-steroidal antiinflammatory analgesic drugs I Dr. Pethő Gábor Pharmacology of non-steroidal antiinflammatory analgesic drugs II Dr. Pethő Gábor Pharmacology of opioid analgesics I Dr. Pethő Gábor Pharmacology of opioid analgesics II Dr. Pethő Gábor Adjuvant analgesics Dr. Pethő Gábor New targets for development of analgesics I Dr. Pethő Gábor New targets for development of analgesics II Dr. Pethő Gábor 279 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions No exam questions are given. The essay questions of the written exam are based on the material presented. Participants 280 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-FBE CAUSES OF EXPANSION AND PREVENTIVE METHODS IN INFECTIOUS DISEASES DR. ZOLTÁN TIGYI, assistant professor Department of Medical Microbiology and Immunology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 2 – 15 Prerequisites: OAA-MB2 completed + OAP-MI1 completed + OAP-PA1 completed Topic The aims of the course to help the students to get acquainted with: - some important basic epidemiological methods (both classic and molecular ones) - the factors play roles in spread of infectious diseases inside and outside of the hospital - the methods that prevent and block the spread of infections, - the emerging and re-emerging infections, - the epidemiology and prevention of nosocomial (hospital acquired) infections, - therapeutic principle of preventing and controlling the spread of antibiotic resistance. Conditions for acceptance of the semester - The students have to choose a sub-topic freely from the detailed list which is delineated on the first seminar and they have to prepare a presentation from their chosen topic by means of PowerPoint or other presentation software, under the supervision of the tutor. The lecture has to be given 15 minutes in duration. - Further requirements: the student should give right answers to the basic questions of the topics that are currently under discussion and further active participation is also required on the seminars. - Assessment: active participation on seminars: ~20%, the shown presentation: ~80%. - In case of insufficient performance: 3 assay questions have to be answered, either oral or written form by common assent. Mid-term exams Making up for missed classes The opportunity of the personal appointment is assured and the copies of the slides of the lecturer are available in electronic format (PDF). Reading material - Obligatory literature - Literature developed by the Department The slides of the seminars in PDF-file format. - Notes - Recommended literature Internet resources: www.cdc.gov/, http://ecdc.europa.eu/en/ www.oek.hu/oek.web,www.who.int/en/ www2.sph.unc.edu/courses/eric/index.html www.pitt.edu/~super1/ www.maine.gov/dhhs/boh/ddc/ www2.sph.unc.edu/nccphp/training/all_trainings/at_epidme Lectures Practices Seminars 1 2 3 4 5 6 Basic concepts, aims and tools, short historical introduction. Basic concepts, aims and tools, short historical introduction. The transmission of infections (vectors, reservoirs) The transmission of infections (vectors, reservoirs) The traditional epidemiologic methods (biostatistics, laboratory identification of pathogens) The traditional epidemiologic methods (biostatistics, laboratory identification of pathogens) 281 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Molecular epidemiologic methods of infectious diseases. Molecular epidemiologic methods of infectious diseases. How do environmental factors (climate, society, nutrition, human behaviour ...) affect the spread of infectious diseases? How do environmental factors (climate, society, nutrition, human behaviour ...) affect the spread of infectious diseases? Emerging and re-emerging Infections. Emerging and re-emerging Infections. The risk of bioterrorism and its epidemiologic background I The risk of bioterrorism and its epidemiologic background I The risk of bioterrorism and its epidemiologic background II The risk of bioterrorism and its epidemiologic background II Epidemiology of the nosocomial (hospital acquired) infections I Epidemiology of the nosocomial (hospital acquired) infections I Epidemiology of the nosocomial (hospital acquired) infections II Epidemiology of the nosocomial (hospital acquired) infections II The aims and methods of the infectious disease surveillance. The aims and methods of the infectious disease surveillance. Factors and measures helping and inhibiting the development of antimicrobial resistance. Factors and measures helping and inhibiting the development of antimicrobial resistance. The possibilities of the prevention of infectious diseases (specific methods; vaccination; aspecific methods....) The possibilities of the prevention of infectious diseases (specific methods; vaccination; aspecific methods....) Evaluation of the students on the basis of: Presentations given of their chosen topic during the course and their activity during the seminars. Evaluation of the students on the basis of: Presentations given of their chosen topic during the course and their activity during the seminars. Filling up feedback questionnaire. Exam topics/questions The major topics are delineated in details on the first seminar. The sub-topics of the presentation of the students are subjected to negotiation. Participants Dr. Tigyi Zoltán (TIZHAAE.PTE) 282 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-GER BASICS OF GERONTOLOGY DR. ERIKA RITTMANN-PÉTERVÁRI, assistant professor Department of Pathophysiology and Gerontology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 100 Prerequisites: OAP-BPR completed + OAP-KO1 completed Topic The population is aging. Knowledge of special physiological, psychosocial aspects, age-related problems and methods of care may help adequate health provision for the elderly patients. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Answering the questions of a written account. Making up for missed classes Writing an essay from the topic of the omitted lecture. Reading material - Obligatory literature - Literature developed by the Department Lecture slides will be uploaded to Coospace. - Notes - Recommended literature Rathway: The Merck Manual of Geriatrics, MSD, 1990 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 Concepts of gerontology. Demography Dr. Székely Miklós Biological/chronological age. Physiological aging Dr. Székely Miklós Biological theories of aging I Dr. Balaskó Márta Biological theories of aging II Dr. Balaskó Márta Acute/chronic diseases, polimorbidity in the elderly Dr. Székely Miklós Problems of diagnosis and therapy Dr. Székely Miklós Homeostatic functions and aging Dr. Székely Miklós Adaptability, vulnerability Dr. Székely Miklós Cardiorespiratory disorders in the elderly I Dr. Soós Szilvia Cardiorespiratory disorders in the elderly II Dr. Soós Szilvia Changes of energy balance Rittmann-né Dr. Pétervári Erika Gastrointestinal changes in the elderly Rittmann-né Dr. Pétervári Erika Endocrine changes with age Dr. Garai János 283 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Diabetes mellitus in the elderly Dr. Garai János Renal functions: changes with age Dr. Székely Miklós Salt/water balance changes with age Dr. Székely Miklós Geriatric syndromes I Dr. Székely Miklós Geriatric syndromes II Dr. Székely Miklós Gait disorders, motor system in the elderly Dr. Sarlós Gézáné Aging and immune processes Dr. Sarlós Gézáné Psychosocial factors in gerontology I Dr. Lampek Kinga Psychosocial factors in gerontology II Dr. Lampek Kinga Problems of the caretaking team Dr. Heim Szilvia Chronic care, nursing Dr. Heim Szilvia Rehabilitation Dr. Székely Miklós Hospice Dr. Székely Miklós Test-exam Rittmann-né Dr. Pétervári Erika Test-exam Rittmann-né Dr. Pétervári Erika Practices Seminars Exam topics/questions Written account (test) from the topics of the course. Participants 284 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-KK2 CLINICAL PATHOPHYSIOLOGY 2 DR. MIKLÓS SZÉKELY, professor emeritus Department of Pathophysiology and Gerontology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAP-KO2 parallel Topic The task is to apply the information from pathophysiology in clinical practice. The pathophysiological backgrounds of clinical disorders originating from the gastrointestinal system, energy balance, intermediary metabolism or the endocrine systems are to be analyzed. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes Not needed, because of test Reading material - Obligatory literature - Literature developed by the Department Most lectures will appear on CooSpace by the end of the semester - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Disorders of urate metabolism Dr. Szekeres-Solymár Margit Malnutrition, clinical nutrition Dr. Garai János Hepatotoxins Dr. Pár Alajos Dysfunctions of the colon Dr. Czimmer József Gastroesophageal reflux disease Dr. Vincze Áron Endre Disorders of body composition, obesity Dr. Molnár Dénes Lipid-disorders in the clinical practice Dr. Bajnok László Zoltán Late complications of diabetes Dr. Wittmann István Acute abdomen in pediatrics Dr. Józsa Gergő Fundaments of diabetes therapy Dr. Wittmann István Iodine-metabolism, thyroid function Dr. Mezősi Emese Diabetes insipidus, SIADH, natriuretic peptides Dr. Mezősi Emese Disorders of gonadal hormones Dr. Garai János Test-exam Dr. Székely Miklós 285 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions Participants 286 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-KLP CLINICOPATHOLOGY DR. LÁSZLÓ PAJOR, professor Department of Pathology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 200 Prerequisites: OAP-PA1 completed Topic During the course of pathology the clinicopathological view is emphasized in order to aid the synthesis of clinical and laboratory data and alterations detected by macro- and microscopical examination. The development of basic clinicopathological thinking and differential diagnostic skills is required by the end of the pathology curriculum, which is further supported by the demonstration of a case related to the subject of lectures every week. Clinician partners will also contribute to the demonstrations. Attendants are supposed to accomplish written text examination by the end of the course. Conditions for acceptance of the semester Acceptance of the semester: according to the Code of Studies of Examination Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature S. L. Robins, V. Kumar: Basic Pathology, 7th edition, Saunders Company, 2003 ISBN 0-7216-9274-5 Pajor L.: Pathologic Catechism, 2015 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Clinicopathology Dr. László Terézia Clinicopathology Dr. László Terézia Clinicopathology Dr. Pajor László Clinicopathology Dr. Pajor László Clinicopathology Dr. Pajor László Clinicopathology Dr. Pajor László Clinicopathology Dr. Pajor László Clinicopathology Dr. Kajtár Béla Clinicopathology Dr. Kovács Krisztina Clinicopathology Dr. Smuk Gábor Clinicopathology Dr. Kajtár Béla Clinicopathology Dr. Kereskai László 287 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Clinicopathology Dr. Semjén Dávid Clinicopathology Dr. Kravják András Practices Seminars Exam topics/questions Type of exam: test, progress grade Participants 288 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-KMT CASE REPORTS IN CLINICAL MICROBIOLOGY DR. LEVENTE EMŐDY, professor emeritus Department of Medical Microbiology and Immunology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ both semesters semester ▪ recommended semester: 6 Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours Course headcount limitations (min.-max.): 1 – 100 Prerequisites: OAA-IMM completed + OAP-MI1 completed + OAP-PA1 completed Topic The course deals with common and special cases of infectious diseases discussing the case history, clinical and laboratory diagnosis, therapy and prevention. 1-2 case studies will be discussed with microbiological demonstration in each lecture. The lectures are problem solving in character, and they need a common thinking with the students. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Oral checkup at the last lecture. Offering an alternative day for those not present. Making up for missed classes Individual preparation from the recommended books, the lecture slides, and from notes of fellow-students Reading material - Obligatory literature - Literature developed by the Department Slides to every case report. - Notes - Recommended literature Gilligan P.H. Smiley M.L., Shapiro D.S.: Cases in Medical Microbiology and Infectious Diseases, 3rd edition, American Society for Microbiology, 2002. http://highered.mcgraw-hill.com/sites/0072320419/student_view0/clinical_case_studies.html# http://www.kcom.edu/faculty/chamberlain/index.htm#Clinical%20Cases Lectures 1 2 3 4 5 6 7 8 9 10 11 Pyoderma case story Dr. Emődy Levente Pyoderma discussion Dr. Emődy Levente Food poisoning case story Dr. Emődy Levente Food poisoning discussion Dr. Emődy Levente Pharyngotonsillitis case story Dr. Emődy Levente Pharyngotonsillitis discussion Dr. Emődy Levente Urinary tract infection case story Dr. Emődy Levente Urinary tract infection discussion Dr. Emődy Levente Bacterial haemolysis case story Dr. Emődy Levente Bacterial haemolysis discussion Dr. Emődy Levente Salmonellosis case story Dr. Emődy Levente 289 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 15 16 17 18 19 20 21 22 23 24 Salmonellosis discussion Dr. Emődy Levente Botulismus case story Dr. Emődy Levente Botulismus discussion Dr. Emődy Levente Gas gangrene case story Dr. Emődy Levente Gas gangrene discussion Dr. Emődy Levente Intrauterine infection case story Dr. Emődy Levente Intrauterine infection discussion Dr. Emődy Levente Meningitis case story Dr. Emődy Levente Meningitis discussion Dr. Emődy Levente Influenza case story Dr. Emődy Levente Influenza discussion Dr. Emődy Levente HIV infection case story Dr. Emődy Levente HIV infection discussion Dr. Emődy Levente Practices Seminars Exam topics/questions Delivery of the exam questions in advance would interfere with the aim of the course as students could figure out in advance the subject of the cases to be presented. Questions on the individual topics will be made open for the participants right after the individual lectures. Participants 290 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-MAO BEHAVIORAL MEDICINE DR. JÓZSEF VARGA, assistant professor Department of Behavioural Sciences Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 16 Prerequisites: OAP-MT5 completed Topic Strong evidences support that health condition, illness and life expectancies are determined by the individual’s life style and behavior. Patients’ illness behavior and coping abilities have an impact on the outcome of illness and rehabilitation. This course introduces into the processes of health behavior and behavior changing focusing on the therapeutic aspects of chronic diseases and specific clinical fields. Conditions for acceptance of the semester According to the Code of Studies and Examinations. Mid-term exams Making up for missed classes Additional homework. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Feldman, M. D., Christensen, J.F. (eds.): Behavioral Medicine in Primary Care. A practical Guide, Appleton and Lange, Stamford, Connecticut, 1997. Csabai, M., Molnar, P.: Health, Illness and Care. A Textbook of Medical Psychology, Springer Orvosi Kiadó, Budapest, 2000. Kaptein, A., Weinman, J. (eds.): Health Psychology, BPS Blackwell Publishing, 2004. Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Models of health and illness. Influence of behavior on health and illness. Models of health and illness. Influence of behavior on health and illness. Psychovegetative correlates of behavior and emotions. Psychovegetative correlates of behavior and emotions. Relationship, understanding, compliance, adherence in the practice of behavioral medicine. Relationship, understanding, compliance, adherence in the practice of behavioral medicine. Behavioral and psychological aspects of chronic illness. Behavioral and psychological aspects of chronic illness. Psychosocial risk factors and psychological rehabilitation of cardiovascular diseases. Psychosocial risk factors and psychological rehabilitation of cardiovascular diseases. Psychosomatics of gastrointestinal diseases and eating disorders. Psychosomatics of gastrointestinal diseases and eating disorders. Psychological reactions, risk factors and coping in oncological diseases. Psychoimmunology. Psychological reactions, risk factors and coping in oncological diseases. Psychoimmunology. Psychological issues in gynecology and pulmonology. Psychological issues in gynecology and pulmonology. Pain syndrome, psychological methods of pain management. Pain syndrome, psychological methods of pain management. Behavioral medicine in treatment of dependencies. Behavioral medicine in treatment of dependencies. Cognitive approaches in behavioral medicine. Cognitive approaches in behavioral medicine. Behavioral methods in general practice. Behavioral methods in general practice. 291 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 25 26 27 28 Behavior, culture and illness. Behavior, culture and illness. Summary, discussion, exam. Summary, discussion, exam. Seminars Exam topics/questions Presentation of a topic + final test Participants Dr. Varga József (VAJGABO.PTE) 292 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-NDG NEUROLOGICAL DIFFERENTIAL DIAGNOSIS DR. ÁGNES SEBŐK, assistant professor Department of Neurology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 20 Prerequisites: OAA-EL2 completed + OAA-NEA completed Topic Through interactive discussion of neurological cases, the diagnosis and differential diagnosis of specific neurological problems will be studied. History, symptoms, and test results will be analysed, based on previous studies in neurophysiology, neuropathology and radiology. Plenty of pictures, videos and some bed-side patient-demonstration will be included. Conditions for acceptance of the semester As usual Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department www.cncs.hu - Notes - Recommended literature Lectures 1-14 Case study Dr. Sebők Ágnes Practices Seminars Exam topics/questions www.cncs.hu Participants 293 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-TD4 STUDENT PROJECT RESEARCH 4 DR. PÉTER BALOGH, associate professor Undergraduate Research Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ both semesters semester ▪ recommended semester: 6 Number of hours/semester: 0 lectures + 24 practices + 0 seminars = total of 24 hours Course headcount limitations (min.-max.): 1 – 300 Prerequisites: OAE-TD3 completed Topic The aim of this subject is to nurture and promote the activity of students sufficiently motivated to perform biomedical project research. The students may progressively enrol to four parts in four separate semesters, for the total credit value of 8. For acknowledging the 3rd and 4th (elective) parts, the student must train research student novice(s). In case of changing the place of work, the subject series can not be re-started. The subject’s administrator is the actual Chairman of the Students’ Research Society (SRS) of the Faculty of Medicine. Conditions for acceptance of the semester To enrol this course a registered SRS membership and completion of Student Project Research 1/2 are mandatory. Acknowledging the course requires first-author presentation of work at a Students’ conference (UP or elsewhere) or Dean’s assay, or presentation at any professional conference relevant to the research field. Grades will be accorded corresponding to the criteria set out in the Rules and Regulations of SRS. For detailed requirements please read the following document: http://aok.pte.hu/run/download2.php?idf=11791&nyelv=eng Mid-term exams Making up for missed classes Not applicable Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Not applicable Lectures Practices 1-24 Research Seminars Exam topics/questions Not applicable Participants Dr. Balogh Péter (BAPOAGP.PTE) 294 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-TFS PERFORMANCE-ENHANCING DRUGS. PHYSIOLOGY, PHARMACOLOGY ASPECTS AND CLINICAL DR. GÁBOR POZSGAI, assistant professor Department of Pharmacology and Pharmacotherapy Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 0 lectures + 0 practices + 12 seminars = total of 12 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAA-EL2 completed Topic The course covers performance-enhancing drugs widely used by athletes. After reviewing history and legal control, main groups of performance-enhancing agents are discussed. Physiological and pharmacological characteristics of individual drugs are delineated. Practical aspects of performance-enhancing compounds for clinicians are illustrated through examples. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Written exam at the end of the course. Making up for missed classes Not possible. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Michael S. Bahrke, Charles E. Yesalis: Performance Enhancing Substances in Sport and Exercise, 1st edition, Human Kinetics, 2002. David R. Mottram: Drugs in Sport, 5th edition, Routledge, 2010. Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 Introduction Anabolic steroids I Anabolic steroids II Beta 2 receptor agonists Creatine Dietary supplements Gene doping and recent methods I Gene doping and recent methods II Enhancement of oxygen transport Diuretics and other masking agents Prohibited methods Peptide hormones and psychomotor stimulants Exam topics/questions 1 Introduction 2 Anabolic steroids I 3 Anabolic steroids II 4 Beta 2 receptor agonists 5 Creatine 6 Dietary supplements 7 Gene doping and recent methods I 8 Gene doping and recent methods II 9 Enhancement of oxygen transport 295 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 10 Diuretics and other masking agents 11 Prohibited methods 12 Peptide hormones and psychomotor stimulants Participants Dr. Pozsgai Gábor (POGFAAO.PTE) 296 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-AMM INTRODUCTION AND BASICS OF OPERATIONAL MEDICINE DR. TAMÁS MOLNÁR F., professor Department of Operational Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 22 lectures + 6 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 25 Prerequisites: OAP-KO1 completed Topic After defining the concept of Operational Medicine, we address the peculiarities of healthcare under special/extreme conditions and circumstances. For the attainment of an extended knowledge about the background of the subject, it is necessary to study the structure and management system of the armed forces, as well as the bases of international and Hungarian military organizations and treaties. We will try to give a general idea of Military Medicine, Disaster Medicine and Law Enforcement Medicine, and of their differences compare to other medical work areas. Teaching materials used by NATO, The Hungarian Defence Forces and the Ministry of the Interior are also applied in the subject-matter of instruction. The course is interactive - for the deeper understanding of emerging issues during the semester, manual trainings will also be held. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams TEST - at the end of the semester. Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department Teaching materials of the course (from the instructors). - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 The concept of Operational Medicine. The status of Military Medicine, Disaster Medicine and Law Enforcement Medicine in Hungary Dr. Rendeki Szilárd The concept of Operational Medicine. The status of Military Medicine, Disaster Medicine and Law Enforcement Medicine in Hungary Dr. Rendeki Szilárd Basics of Armed Forces. The structure of The Hungarian Defence Forces and the NATO Dr. Loibl Csaba Basics of Armed Forces. The structure of The Hungarian Defence Forces and the NATO Dr. Loibl Csaba Tactical Emergency Medical Support Dr. Rendeki Szilárd Tactical Emergency Medical Support Dr. Rendeki Szilárd Tactical Combat Casualty Care. The NATO MILMED COE Dr. Rendeki Szilárd Tactical Combat Casualty Care. The NATO MILMED COE Dr. Rendeki Szilárd Refugee camp, improvised service conditions Dr. Rendeki Szilárd Refugee camp, improvised service conditions Dr. Rendeki Szilárd 297 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 15 16 17 18 19 20 21 22 Operational Medicine in historical perspective - Case-book. Extramedicinal representation Dr. Molnár F. Tamás Operational Medicine in historical perspective - Case-book. Extramedicinal representation Dr. Molnár F. Tamás Medical experiences learnt from recent wars: Vietnam to Afghanistan Dr. Molnár F. Tamás Medical experiences learnt from recent wars: Vietnam to Afghanistan Dr. Molnár F. Tamás Weapon knowledge, ballistics. Mechanics of injuries. Dr. Rendeki Szilárd Weapon knowledge, ballistics. Mechanics of injuries. Dr. Rendeki Szilárd Mass treatment of the wounded. Triage - in theory/in practice Dr. Nagy Bálint János Mass treatment of the wounded. Triage - in theory/in practice Dr. Nagy Bálint János Medical aspects of CBRN warfare Dr. Rendeki Szilárd Medical aspects of CBRN warfare Dr. Rendeki Szilárd Test Dr. Rendeki Szilárd Test Dr. Rendeki Szilárd Practices 1 2 3 4 5 6 Triage - Training in practice Triage - Training in practice Triage - Training in practice Triage - Training in practice Triage - Training in practice/field work Triage - Training in practice/field work Seminars Exam topics/questions Participants Dr. Loibl Csaba (LOCGAAO.PTE), Dr. Molnár F. Tamás (MOFMAAO.PTE), Dr. Nagy Bálint János (NABGAAO.PTE), Dr. Rendeki Szilárd (RESGABA.PTE) 298 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-DRH MICROBIOLOGY CASES OF HOUSE M.D. DR. ÉVA MIKÓ, assistant professor Department of Medical Microbiology and Immunology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 4 – 50 Prerequisites: OAP-MI1 completed Topic Interactive microbiology case studies based on the episodes of House M.D. Problem solving discussion after watching the actual scene. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Personal consultation Making up for missed classes Personal consultation Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Patrick R. Murray, Ken S. Rosenthal, and Michael A. Pfaller: Medical Microbiology, 7th edition, 2013 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Leprosy Dr. Szereday László Leprosy Dr. Szereday László Lyme disease Dr. Szereday László Lyme disease Dr. Szereday László HIV Dr. Szereday László HIV Dr. Szereday László Psittacosis Dr. Szereday László Psittacosis Dr. Szereday László Syphilis Dr. Szereday László Syphilis Dr. Szereday László SSPE Dr. Szereday László SSPE Dr. Szereday László Gonorrhea Dr. Szereday László Gonorrhea Dr. Szereday László 299 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Rickettsialpox Dr. Szereday László Rickettsialpox Dr. Szereday László Leptospirosis Dr. Szereday László Leptospirosis Dr. Szereday László Rabies Dr. Szereday László Rabies Dr. Szereday László Hepatitis C Dr. Szereday László Hepatitis C Dr. Szereday László Herpes simplex Dr. Szereday László Herpes simplex Dr. Szereday László Bartonellosis Dr. Szereday László Bartonellosis Dr. Szereday László Consultation and exam Dr. Szereday László Consultation and exam Dr. Szereday László Practices Seminars Exam topics/questions See lecture topics Participants 300 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EMV MICROBIOLOGICAL ASPECTS OF FOOD SAFETY Course director: DR. ISTVÁNNÉ BÁTAI (DR. MÓNIKA KERÉNYI), associate professor Department of Medical Microbiology and Immunology 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours Course headcount limitations (min.-max.): 1 – 35 Prerequisites: OAP-MI1 completed Topic Topic gives knowledge of foodborne diseases and useful probiotics. - Advantages and disadvantages of probiotics in different diseases, dangers of imported contaminated food, and information of newest methods in food safety are discussed. The students get knowledge of - advantages and disadvantages of microorganisms in food for health - role of probiotics in therapy, probiotic products - dangers of imported food contaminated by pathogens and their toxins - epidemiology and prevention of foodborne diseases - antibiotics in food - detection methods Conditions for acceptance of the semester Active participation Mid-term exams 1 MCQ test Making up for missed classes Consultation Reading material - Obligatory literature - Literature developed by the Department Lectures on the Coospace - Notes Handout on the Coospace - Recommended literature Jay JM: Modern Food Microbiology, research papers and review articles Lectures Practices Seminars 2 3 4 5 6 7 8 9 10 11 12 13 History of food microbiology Microorganisms in food production Factors influencing the growth of microorganisms in food Probiotics in food, probiotic products and their application Bacterial food poisoning Mycotoxins and their effects Foodborne diseases I Foodborne diseases II Epidemiology of foodborne diseases Antibiotics and antimicrobial compounds in food New and old methods in food investigation Summary of the topics and exam Exam topics/questions MCQ test 301 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Participants Dr. Bátai Istvánné (KEMHAAP.PTE) 302 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-IVF INFECTIONS AND IMMUNITY DR. JÚLIA BARTHÓ-SZEKERES, professor Department of Medical Microbiology and Immunology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 4 – 50 Prerequisites: OAA-IMM completed + OAP-MI1 completed Topic The importance of anti-infectious immunity is not restricted to elimination of pathogens, but is also responsible for long lasting protection, as well as -in some cases- immunopathological disorders Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Making up for missed classes Consultation Reading material - Obligatory literature - Literature developed by the Department Lecture slides - Notes - Recommended literature 1. H. Chapel, M. Haeney, N. Misbah, Snowden: Clinical Immunology, Blackwell, 2008 2. S. Kartikeyan, R.N. Bharmal, R.P. Tiwari, and P.S. Bisen: HIV and AIDS: Basic Elements and Priorities, 2007 3. T. Platts-Mills and Johannes Ring: Allergy in Practice, 2003 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Non-specific defence. Surface barriers, normal colonizing flora, phagocytosis, complement system. Dr. Barthóné Dr. Szekeres Júlia Non-specific defence. Surface barriers, normal colonizing flora, phagocytosis, complement system. Dr. Barthóné Dr. Szekeres Júlia Antigen presentation and recognition. Dendritic cells, pattern recognition receptors. Dr. Barthóné Dr. Szekeres Júlia Antigen presentation and recognition. Dendritic cells, pattern recognition receptors. Dr. Barthóné Dr. Szekeres Júlia Defence against extracellular microorganisms. The role of immunoglobulin classes. Mucosal immunity. Dr. Barthóné Dr. Szekeres Júlia Defence against extracellular microorganisms. The role of immunoglobulin classes. Mucosal immunity. Dr. Barthóné Dr. Szekeres Júlia Defence against intracellular microorganisms. Defence against viral infections. Viruses and immunosuppression. Dr. Barthóné Dr. Szekeres Júlia Defence against intracellular microorganisms. Defence against viral infections. Viruses and immunosuppression. Dr. Barthóné Dr. Szekeres Júlia Defence against parasitic infections. Micro-and macroparasite infections that polarize the immune response. Dr. Barthóné Dr. Szekeres Júlia Defence against parasitic infections. Micro-and macroparasite infections that polarize the immune response. Dr. Barthóné Dr. Szekeres Júlia Evasion and use of the innate and adaptive immune responses by microorganisms. Dr. Barthóné Dr. Szekeres Júlia Evasion and use of the innate and adaptive immune responses by microorganisms. Dr. Barthóné Dr. Szekeres Júlia 303 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Healing of infectious diseases. The pathogenic role of anti-infectious immunity; local inflammation, systemic inflammation, sepsis, endotoxin shock, toxic shock syndrome. Dr. Barthóné Dr. Szekeres Júlia Healing of infectious diseases. The pathogenic role of anti-infectious immunity; local inflammation, systemic inflammation, sepsis, endotoxin shock, toxic shock syndrome. Dr. Barthóné Dr. Szekeres Júlia The pathogenic role of anti-infectious immunity; hypersensitivity reactions in bacterial-parasitic and fungal infections. Dr. Barthóné Dr. Szekeres Júlia The pathogenic role of anti-infectious immunity; hypersensitivity reactions in bacterial-parasitic and fungal infections. Dr. Barthóné Dr. Szekeres Júlia Induction of autoimmunity; molecular mimicri, epitope spreading, polyclonal T or B cell activation. Dr. Barthóné Dr. Szekeres Júlia Induction of autoimmunity; molecular mimicri, epitope spreading, polyclonal T or B cell activation. Dr. Barthóné Dr. Szekeres Júlia Immunopathological alterations following viral infections. The involvement of CD8+ T cells. Dr. Barthóné Dr. Szekeres Júlia Immunopathological alterations following viral infections. The involvement of CD8+ T cells. Dr. Barthóné Dr. Szekeres Júlia Immunopathological alterations following viral infections. The involvement of CD4+ T cells. Dr. Barthóné Dr. Szekeres Júlia Immunopathological alterations following viral infections. The involvement of CD4+ T cells. Dr. Barthóné Dr. Szekeres Júlia Immunopathological alterations following viral infections. The involvement of antibodies. Dr. Barthóné Dr. Szekeres Júlia Immunopathological alterations following viral infections. The involvement of antibodies Dr. Barthóné Dr. Szekeres Júlia Vaccination; Type of vaccines, requirements for vaccines. Dr. Barthóné Dr. Szekeres Júlia Vaccination; Type of vaccines, requirements for vaccines. Dr. Barthóné Dr. Szekeres Júlia Vaccination; rational vaccine development, mandatory vaccines. Dr. Barthóné Dr. Szekeres Júlia Vaccination; rational vaccine development, mandatory vaccines. Dr. Barthóné Dr. Szekeres Júlia Practices Seminars Exam topics/questions The same as lecture topics Participants 304 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-KPR CHEMOPREVENTION DR. TÍMEA VARJAS, assistant professor Department of Public Health Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 30 Prerequisites: OAA-MB2 completed Topic Chemoprevention is the administration of natural or (semi)synthetic agents to prevent, inhibit, or delay the progression of chronic diseases. The focus is on cancer chemoprevention. The way from a potent agent to a chemopreventive strategy will also be discussed. Involving (chemo)preventive interventions in every-day practice could spare valuable life years. Conditions for acceptance of the semester Absences should not exceed 15% of lectures and practicals (2x45 min). Otherwise signature of grade book is denied. Examination: test Mid-term exams Exam: test after the last lecture. Re-take exam in the exam period. Making up for missed classes Based on individual consideration Reading material - Obligatory literature - Literature developed by the Department PPT-presentations (CooSpace) - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Introduction; Chemoprevention as a preventive strategy Dr. Szabó István Introduction; Chemoprevention as a preventive strategy Dr. Szabó István Finding evidence Dr. Szabó István Finding evidence Dr. Szabó István Interventing chronic diseases I Dr. Szabó István Interventing chronic diseases I Dr. Szabó István Interventing chronic diseases II Dr. Szabó István Interventing chronic diseases II Dr. Szabó István Chemopreventive strategies - antioxidants Dr. Szabó István Actualities of antioxidants Dr. Szabó István Natural chemopreventive agents Dr. Szabó István Natural chemopreventive agents Dr. Szabó István 305 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Chemopreventive dietary factors Dr. Szabó István Chemopreventive dietary factors Dr. Szabó István Practices Seminars Exam topics/questions Coospace Participants 306 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-LLA A SPECTACLE OF VISION DR. PÉTER BUZÁS, associate professor Department of Physiology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 220 Prerequisites: OAA-EL2 completed Topic For most people, vision is the primary source of perception. Quite often, we wonder how it actually works and the answers don’t always seem easy. Why is the sky blue? How many megapixels does the human eye have? Can we really see a single photon? What is blindsight? How does the bull see the red cape? How does 3D movie work? This course is aimed at answering many questions of this kind but also at raising some that puzzle researchers today. We will present live demonstrations, illusions and discuss experiments that led to important discoveries in order explain the neural mechanisms of vision in an interesting way. We will also talk about diseases causing loss of visual functions as well as about animal vision. The course begins with an introduction to psychophysical and neurophysiological research methods and a little light physics. Then we follow the path and processing of visual information from the photoreceptors to higher visual cortical areas. In the second part, we talk about some of the visual sub-systems including color vision, stereopsis, motion perception and eye movements followed by visual attention, reading and synesthesia. To conclude the course, we discuss visual illusions that won the latest Best Illusion of the Year Contest. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Two mid-term tests based on the lectures, to be written on weeks as shown in the course schedule. Test questions will be available online and solutions must be submitted until a deadline. Late submission results in 10% of points being subtracted. Making up for missed classes Lecture slides will be available on CooSpace. Absences up to 25% of the sessions can be made up by passing both mid-term tests. Reading material - Obligatory literature - Literature developed by the Department Lecture slides will be available on CooSpace. - Notes - Recommended literature Robert Sekuler - Randolph Blake: Perception, McGraw Hill Jeremy Wolfe et al.: Sensation and Perception, Sinauer Eric Kandel et al. (ed.): Principles of Neural Science, McGraw Hill Lectures 1 2 3 4 5 6 7 8 9 Sensation and perception. Psychophysical methods Dr. Buzás Péter The methods of neuroscience in vision research Dr. Buzás Péter A little light physics. Radiometry and photometry. Optical system of the eye Dr. Buzás Péter What does the eye doctor look at? Visual field, visual acuity, ophthalmoscopy Dr. Buzás Péter Rods and cones. Dark and light adaptation Dr. Buzás Péter One picture, ten interpretations: functions of retinal ganglion cells. The subcortical channels Dr. Buzás Péter Receptive fields in primary visual cortex. Columns, hypercolumns and maps Dr. Buzás Péter „What?” and „where?” Parallel processing in the visual cortex Dr. Buzás Péter Building blocks of pattern and form perception Dr. Buzás Péter 307 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Visual perception and cognition. Gestalts and grandmother cells Dr. Buzás Péter Consultation Dr. Buzás Péter Mid-term test 1 Dr. Buzás Péter The color stimulus. What are cones good for? Dr. Buzás Péter Color opponency and opponent colors Dr. Buzás Péter Color appearance. The names of colors. Color constancy. Subjective colors Dr. Buzás Péter The case of the bull with the red cape. Disorders of color vision Dr. Buzás Péter Depth perception with one eye Dr. Buzás Péter Depth perception with two eyes. Hoes does 3D movie work? Dr. Buzás Péter Development and disorders of depth perception Dr. Buzás Péter Sensing and perceiving visual motion. Optic flow Dr. Buzás Péter What do we use visual motion perception for? Navigation. Biological motion Dr. Buzás Péter Look and see: the eye movements Dr. Buzás Péter The spotlight of attention. Visual search. The attentional blink Dr. Buzás Péter Physiological mechanisms of attention. Disorders of visual attention Dr. Buzás Péter Reading and dyslexia. Synesthesia: Wednesday is indigo blue Dr. Buzás Péter Winning illusions of the latest Best Illusion of the Year Contest Dr. Buzás Péter Consultation Dr. Buzás Péter Mid-term test 2 Dr. Buzás Péter Practices Seminars Exam topics/questions Test questions will be based on the lectures and topics covered in the lecture slides. Participants 308 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MST MICROSURGICAL TECHNIQUES DR. GÁBOR JANCSÓ, associate professor Department of Surgical Research and Techniques Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 0 lectures + 14 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3–6 Prerequisites: OAP-MUA completed + OAP-SPR parallel Topic The aim of the course is to get acquainted with microsurgical techniques. Students gain insight into the handling and maintenance of microsurgical tools and instruments as well as the personal and material demands of microsurgery, the indications, limits and results of this technique. Besides reviewing the general rules of microvascular anastomoses and nerve reconstruction, students acquire the handling of microsurgical tools and instruments during individually performed microsurgical operations on rats. Conditions for acceptance of the semester According to the code of studies. Mid-term exams Making up for missed classes http://soki.aok.pte.hu/ Reading material - Obligatory literature - Literature developed by the Department http://soki.aok.pte.hu/ - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Microsurgical instruments and suturing techniques Microsurgical instruments and suturing techniques Abdominal aorta preparation and anastomosis in rat Abdominal aorta preparation and anastomosis in rat Carotid artery preparation and anastomosis in rat Carotid artery preparation and anastomosis in rat Femoral artery preparation and anastomosis in rat Femoral artery preparation and anastomosis in rat Peripheral nerve reconstruction in rat Peripheral nerve reconstruction in rat Introduction into the microsurgery Microsurgical suture techniques Pitfalls of microvessel anastomoses Injuries and reconstruction of peripheral nerves Seminars Exam topics/questions http://soki.aok.pte.hu/ Participants Bognár Laura (BOLOAA-O.PTE), Dr. Hardi Péter (HAPFAAO.PTE), Dr. Jancsó Gábor (JAGMAAO.PTE), Dr. Nagy Tibor Aladár (NATIAAO.PTE), Dr. Takács Ildikó (TAIFAAO.PTE) 309 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-N28 CLINICAL HUNGARIAN 2 DR. GÁBOR RÉBÉK-NAGY, associate professor Department of Languages for Specific Purposes Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 6 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OAE-H4A completed Topic The aim of the course is to help foreign students of the English Programme survive during their clinical studies in Hungary through developing appropriate language competencies and also widen the scope of existing competencies in the field of doctor-patient communication. At present teaching in Medical Hungarian is provided in the first 4 semesters when students do not participate in clinical studies. Therefore this course offered for the fifth and sixth semesters to enable students to cope with language, tasks in their clinical studies. Conditions for acceptance of the semester Participation in practicles is obligatory. Absences exceeding 15% but below 25% of the total number of contact hours can be excused by the group tutor. In case absences exceed 25% of the total number of contact hours the course must be regarded as uncompleted. Mid-term exams Making up for missed classes To be discussed with the course tutor in each individual case. Reading material - Obligatory literature - Literature developed by the Department Mária Győrffy: English for Doctors, Idióma Bt. Pécs 2001 - can be purchased in the Department - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Anamnézis felvétel, családi és szociális anamnézis - History taking, (family and social history) Anamnézis felvétel, családi és szociális anamnézis - History taking, (family and social history) Korábbi betegségek, panasz, fájdalom jellege, iránya, helye - Previous illnesses, complaints, character, radiation, location of pain Korábbi betegségek, panasz, fájdalom jellege, iránya, helye - Previous illnesses, complaints, character, radiation, location of pain A leggyakrabban használt lehetséges magyar kérdések és válaszok a belgyógyászatban - The most frequently used questions and answers in Internal Medicine A leggyakrabban használt lehetséges magyar kérdések és válaszok a belgyógyászatban - The most frequently used questions and answers in Internal Medicine Kórlap kitöltése - Writing medical records Kórlap kitöltése - Writing medical records Párbeszéd írása megadott információs alapján. - Wiriting dialogues on the basis of given information Párbeszéd írása megadott információs alapján. - Wiriting dialogues on the basis of given information Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 1. - Improving listening comprehension on the basis of dialogues and case studies 1 Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 1. - Improving listening comprehension on the basis of dialogues and case studies 1 Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 2. - Improving listening comprehension on the basis of dialogues and case studies 2 Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 2. - Improving listening comprehension on the basis of dialogues and case studies 2 Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 3. - Improving listening comprehension on the basis of dialogues and case studies 3. Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 3. - Improving listening comprehension on the basis of dialogues and case studies 3. 310 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 17 18 19 20 21 22 23 24 25 26 27 28 Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 4. - Improving listening comprehension on the basis of dialogues and case studies 4. Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 4. - Improving listening comprehension on the basis of dialogues and case studies 4. Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 4. - Improving listening comprehension on the basis of dialogues and case studies 4. Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 5. - Improving listening comprehension on the basis of dialogues and case studies 5. Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 5. - Improving listening comprehension on the basis of dialogues and case studies 5. Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 16. - Improving listening comprehension on the basis of dialogues and case studies 6. Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 16. - Improving listening comprehension on the basis of dialogues and case studies 6. Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 7. - Improving listening comprehension on the basis of dialogues and case studies 7 Hallás utáni szövegértés fejlesztése, esettanulmányok és dialógusok alapján 7. - Improving listening comprehension on the basis of dialogues and case studies 7 Teszt - Test Értékelés - Evaluation Értékelés - Evaluation Seminars Exam topics/questions Two written tests – Four oral presentations Participants Dr. Hegedűs Anita (HEAAAA.B.JPTE), Dr. Rébék-Nagy Gábor (REGCAC.B.JPTE), Dr. Warta Vilmos (WAVEAB.B.JPTE), Eklicsné Dr. Lepenye Katalin (EKLAXA.B.JPTE), Hamarné Sávay Judit (HASMAAO.PTE), Hild Gabriella (MAGAAD.B.JPTE), Horváth Lilla Anita (HOLFABP..PTE), Kurdiné Molnár Eszter (KUMPAAK.PTE), Lokodiné Szolcsányi Judit (LOSIAAB.PTE), Mészégetőné Halmos Éva (MEHHABE.PTE), Móriczné Győrffy Mária (MOGPAAP.PTE), Nagy Gabriella (NAGMAAO.PTE), Ronczykné Berta Anikó (BEAAAI.B.JPTE), Szántóné Csongor Alexandra (CSAAAA.B.JPTE), Váradi Katalin (VAKHAAE.PTE) 311 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-VAE PATHOPHYSIOLOGY OF BLOOD CELLS DR. MÁRTA BALASKÓ, associate professor Department of Pathophysiology and Gerontology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 6 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 100 Prerequisites: OAP-KO1 completed Topic The course focuses on the pathophysiology of erythropoiesis and on the structural and functional abnormalities of blood cells at a preclinical level. In addition to those of red blood cells, functions and disorders of leukocytes and platelets are discussed. Related functional and clinical conditions together with the pathophysiological basis of possible therapies will also be included. Theory is complemented by case histories. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams The final test may be repeatedly taken (twice) to improve final grade. Making up for missed classes An essay on the topic of the missed lecture. Reading material - Obligatory literature - Literature developed by the Department Lecture slides are uploaded to CooSpace. - Notes - Recommended literature Hoffbrand, Moss and Pettit: Essential Haematology, 5th edition, Blackwell 2006 ISBN 1-4051-3649-9 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Erythropoiesis Dr. Balaskó Márta Polycythemia vera and spuria: etiology, pathogenesis and complications. Dr. Balaskó Márta Morphology of red blood cells, corpuscular hemolytic anemias I Dr. Balaskó Márta Corpuscular hemolytic anemias II, case histories. Dr. Balaskó Márta Sickle cell anemia: etiology, pathogenesis, pathophysiology of therapeutic possibilities. Dr. Balaskó Márta Thalassemias: etiology, complications, treatment. Case histories. Dr. Balaskó Márta Extracorpuscular hemolytic anemia I Dr. Balaskó Márta Extracorpuscular hemolytic anemia II. Case studies. Dr. Balaskó Márta Abnormalities of the neutrophil granulocytes I. Dr. Balaskó Márta Abnormalities of the neutrophil granulocytes II. Case histories. Dr. Balaskó Márta Abnormalities of eosinophil and basophil granulocytes I Dr. Balaskó Márta Abnormalities of Lymphocytes. Case studies. Dr. Balaskó Márta 312 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Platelets: structure, functions and related pathophysiology. Dr. Balaskó Márta Test. Case histories. Dr. Balaskó Márta Practices Seminars Exam topics/questions The grade depends on the result of the final test. Participants 313 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-AAN GENERAL ANAESTHESIA DR. ISTVÁN BÁTAI, associate professor Department of Anaesthesia and Intensive Therapy Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 100 Prerequisites: OAP-GT1 completed Topic Gives a detailed description of physiology and pharmacology related to general anaesthesia. Describes the conduit of general anaesthesia from preoperative assessment to early postoperative care. Anaesthetic equipment and the risks of anaesthesia are also discussed. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes Personal consultation. Reading material - Obligatory literature - Literature developed by the Department Lecture printouts. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction. The history of anaesthesia. Dr. Bátai István Preoperative evaluation Dr. Bátai István Inhalational anaesthetics I Dr. Bátai István Inhalational anaesthetics II Dr. Bátai István Intravenous anaesthetics Dr. Bátai István Benzodiazepines és opiates Dr. Bátai István Neuromuscular physiology and pharmacology Dr. Bátai István Induction of anaesthesia and the supplementation with regional anaesthesia Dr. Bátai István Airways, difficult intubation Dr. Bátai István Equipment in anaesthesia I Dr. Bátai István Equipment in anaesthesia II Dr. Bátai István Anaesthesia for emergency operations Dr. Bátai István Intraoperative anaesthetic complications Dr. Bátai István Early postoperative care and pain therapy Dr. Bátai István 314 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions Oral exam, according to the thematics. Participants Dr. Bátai István (BAIMABO.PTE) 315 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-AE1 ANAESTHESIA 1 DR. ISTVÁN BÁTAI, associate professor Department of Anaesthesia and Intensive Therapy Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 0 lectures + 0 practices + 12 seminars = total of 12 hours Course headcount limitations (min.-max.): 1 – 50 Prerequisites: OAP-GT1 completed Topic Introduction and the history of anaesthesia. The practical aspects of anaesthetic pharmacology. Basic knowledge of the main anaesthetic techniques, total intravenous and inhalational anaesthesia. Description of anaesthesia machine and the intraoperative monitors. Techniques of airway management. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department Lecture slide - Notes - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 Introduction History of anaesthesia Premedication Intravenous induction agents Total intravenous anaesthesia Inhalational anaesthetics Inhalational anaesthesia Opiates Muscle relaxants Local anaesthetics Anaesthesia machine and monitors Airway maintenance Exam topics/questions Participants Dr. Bátai István (BAIMABO.PTE) 316 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-DGH DIAGNOSTIC METHODS IN GASTROENTEROLOGY AND HEPATOLOGY DR. IMRE SZABÓ, associate professor 1st Department of Internal Medicine Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 40 Prerequisites: OAP-BPR completed + OAP-KO2 completed + OAP-GT2 parallel Topic To review diagnostic tools in Gastroenterology and Hepatology, including demonstration of procedures and clinical interpretation of data. Excellent option to collect more clinical details to main topics of Gastroenterology lectures and bed-side practices. Conditions for acceptance of the semester Maximum 20 % absence and written exam. Mid-term exams Making up for missed classes No organized extra lectures for missed ones. Individual options might be discussed with the study coordinator on a case-by-case basis. Maximum number of absence cannot exceed 3 lectures) Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Kumar and Clark Clinical Medicine Davidson Principles and Practices of Medicine Essentials of Kumar and Clark Medicine Davidson 100 Clinical Cases Mcleaods Clinical Diagnosis Mcleaods Clinical Examinations. Endosonography Hawes, Fockens & Varadarajulu: Expert Consult - online and print, 3rd edition Baron, Kozarek & Carr-Locke: ERCP Expert Consult - online and print, 2nd edition Lectures 0 0 0 0 0 0 0 0 0 0 Imaging studies in the gastrointestinal system. Dr. Battyáni István Interventional radiology in digestive diseases Dr. Battyáni István Isotope studies in GI system. Dr. Bódisné Dr. Zámbó Katalin Physical examination of patients with GI disorders Dr. Szabó Imre Upper gastrointestinal endoscopy. Dr. Szabó Imre Lower gastrointestinal endoscopy. Dr. Vincze Áron Endre Interventional endoscopy. Dr. Szabó Imre Pancreato-biliary endoscopy. Dr. Vincze Áron Endre Endosonography Dr. Pakodi Ferenc PH-metry, gastrointestinal manometry, impedance measurement. Dr. Czimmer József 317 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 0 0 0 0 Proctography, Bilitec, Colon transit, SVS barostat investigations. Dr. Illés Anita Investigations of small intestine. Dr. Czimmer József Functional studies of digestion and absorption. Dr. Vincze Áron Endre Laboratory studies in liver diseases. Dr. Pár Gabriella Practices Seminars Exam topics/questions http://aok.pte.hu/index.php?page=egyseg&egy_id=260&menu=okt_anyag&nyelv=eng (University of Pécs, Medical School / Departments / First Dept. Internal Medicine / Educational Materials) Participants Dr. Battyáni István (BAIHABO.PTE), Dr. Bódisné Dr. Zámbó Katalin (BOZMAAO.PTE), Dr. Czimmer József (CZJFAAO.PTE), Dr. Illés Anita (ILAFAAO.PTE), Dr. Pakodi Ferenc (PAFMAAO.PTE), Dr. Pár Gabriella (PAGFAAO.PTE), Dr. Szabó Imre (SZIHAFE.PTE), Dr. Vincze Áron Endre (VIAQAAP.PTE) 318 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-DON DEPRESSION AND SUICIDE - CLINICAL AND RESEARCH APPROACH DR. SÁNDOR FEKETE, professor Department of Psychiatry and Psychotherapy Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ both semesters semester ▪ recommended semester: 7 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 15 Prerequisites: OAP-GT1 completed Topic Suicide is one of the human possibilities - death can be chosen, while the meaning of this choice is different. It appears to be a personal action, paradoxically, neurobiological and sociocultural factors play an important role in its etiology. Suicidal behaviour is a multiply determined act, but rarely occur outside a context of a psychiatric disorder. The stress–diathesis model of suicide and depression emphasizes both sides of the mind–body coin, the psychological and the biological. In the psychological aspect, past events may have sensitized individuals to see themselves as failures. The biological aspect implicates three biological systems: overactivity of the HPA axis, serotonergic and noradrenergic dysfunction. Mental illnesses, especially depressions are the most replicated predictors for suicides. The course reflects intention to approach and understand the phenomenon of suicide, its relation to depression, brain research, the treatment and prevention in a complex way. Conditions for acceptance of the semester According to the Code of Studies and Examinations Mid-term exams Making up for missed classes According to the Code of Studies and Examinations Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Kaplan Sadock: Synopsis of Psychiatry, 2005 Fekete S., Osvath, P.: Suicide Studies - from Genetics to Psychiatry and Culture, 2005 Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Suicide and depression-historical, cultural-clinical aspect Suicide and depression-clinical aspect, comorbidity Social-epidemiological results Social-epidemiological results Psychological approaches Psychological approaches Psychopathology-personality-temperament, psychobiology Genetics-neurobiology - brain structural - functional changes Genetics-neurobiology - brain structural - functional changes, fMRI Mental disorders and suicide, diagnosis Mental disorders and suicide, diagnosis, fMRI results Psychotherapy, prevention, Biological therapy Pharmacotherapy and brain research data Assisted suicide and euthanasia Exam topics/questions Participants Dr. Fekete Sándor (FESHABE.PTE), Dr. Osváth Péter (OSPMAAO.PTE), Dr. Vörös Viktor (VOVFAAO.PTE) 319 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-GST SPECIAL FIELDS OF PHARMACOLOGY DR. GÁBOR PETHŐ, professor Department of Pharmacology and Pharmacotherapy Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours Course headcount limitations (min.-max.): 5 – 50 Prerequisites: OAP-GT1 completed Topic The aim of the course is to present those fields of pharmacology that are not covered at all or only partially discussed in the compulsory courses Pharmacology 1-2-3 because of time limits. These are the following: use of drugs during pregnancy and lactation; significance of pharmacogenomics in therapy and drug development, pharmacology of retinoids; other drugs used in dermatology; special aspects of drugs used in urology; use of meta-analysis in evaluation of drugs, clinical significance of basic pharmacodynamic and pharmacokinetic parameters; special aspects of drugs used by inhalation, basics of chronopharmacology; pharmacology of contrast media, drugs and chirality. The course wishes to contribute to a better understanding of the use of drugs in the clinical practice and may help students to prepare for the pharmacology exams. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes There is no way to make up for missed lectures. Reading material - Obligatory literature - Literature developed by the Department The material of the lectures is available in PDF format at the Intranet site of the Department of Pharmacology and Pharmacotherapy. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Special aspects of use of drugs during pregnancy and lactation Dr. Pethő Gábor Significance of pharmacogenomics in therapy and drug development Dr. Pethő Gábor Use of meta-analysis in evaluation of drugs Dr. Pethő Gábor Drugs and chirality Dr. Pethő Gábor Clinical significance of pharmacodynamic and pharmacokinetic parameters on the example of drugs used in respiratory diseases I Dr. Pethő Gábor Clinical significance of pharmacodynamic and pharmacokinetic parameters on the example of drugs used in respiratory diseases II Dr. Pethő Gábor Pharmacology of retinoids Dr. Pethő Gábor Drugs (other than retinoids) used in dermatology Dr. Pethő Gábor Urological pharmacology I Dr. Pethő Gábor Urological pharmacology II Dr. Pethő Gábor Pharmacology of contrast media Dr. Pethő Gábor Basics of chronopharmacology Dr. Pethő Gábor 320 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions No exam questions are given. The essay questions of the written exam are based on the material presented. Participants 321 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-IDR BIOPHYSICAL BACKGROUND AND CLINICAL APPLICATION RADIOTHERAPEUTIC METHODS OF ISOTOPDIAGNOSTIC AND DR. KATALIN BÓDIS-ZÁMBÓ, professor Department of Nuclear Medicine Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 20 lectures + 8 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 60 Prerequisites: OAP-BPR completed + OAP-KO2 completed + OAP-PA2 completed Topic A detailed presentation will be given of modern physical biophysical and imaging methods to follow the pathway of radiopharmacons in different organs to earn precise morphological and functional results by the new multimodal systems (SPECT/CT, PET/CT). Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Multiple choice test at the last occasion. When the result is unsuccessful, there is a possibility for oral examination. Making up for missed classes The applicants - in the case of more than one absence (up to maximum three absences in which must not be the consultation or test) should prepare and will be tested from the missed topics given by the instructor. Reading material - Obligatory literature - Literature developed by the Department The presentations are on the website of the Medical Faculty Dept. of Nuclear Medicine in the „Educational materials”. - Notes - Recommended literature It will be announced at the beginning of the course depending on the possibilities of libraries of two departments. A permanent source could be the roaming in the Internet. Lectures 1 2 3 4 5 6 7 8 9 10 Isotopes, radioactive radiations, gamma-camera, SPECT Dr. Lőrinczy Dénes Isotopes, radioactive radiations, gamma-camera, SPECT Dr. Lőrinczy Dénes Work function of PET and its application Dr. Lőrinczy Dénes Work function of PET and its application Dr. Lőrinczy Dénes Diagnostic and therapeutic methods of thyroid and parathyroid glands Dr. Szekeres Sarolta Diagnostic and therapeutic methods of thyroid and parathyroid glands Dr. Szekeres Sarolta Diagnostic methods of respiratory system and inflammation Dr. Bódisné Dr. Zámbó Katalin Diagnostic methods of respiratory system and inflammation Dr. Bódisné Dr. Zámbó Katalin Diagnostic and therapeutic methods of bone and joint system Dr. Schmidt Erzsébet Diagnostic and therapeutic methods of bone and joint system Dr. Schmidt Erzsébet 322 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 15 16 17 18 19 20 Diagnostic methods of urogenital and gastrointestinal systems Dr. Bódisné Dr. Zámbó Katalin Diagnostic methods of urogenital and gastrointestinal systems Dr. Bódisné Dr. Zámbó Katalin Nuclear cardiology Dr. Bódisné Dr. Zámbó Katalin Nuclear cardiology Dr. Bódisné Dr. Zámbó Katalin Nuclear oncology, aspecific methods Dr. Schmidt Erzsébet Nuclear oncology, aspecific methods Dr. Schmidt Erzsébet Nuclear oncology, specific methods and therapy Dr. Schmidt Erzsébet Nuclear oncology, specific methods and therapy Dr. Schmidt Erzsébet Diagnostic methods of central nervous system Dr. Szabó Zsuzsanna Diagnostic methods of central nervous system Dr. Szabó Zsuzsanna Practices 1 2 3 4 5 6 7 8 Presentation of equipment of hot-lab, preparation of radiopharmaceuticals Completion, evaluation and diagnosis of thyroid gland and lung examinations Scintigraphy of bone and medulla, evaluation and diagnosis Evaluation and diagnosis of kidney and liver examinations SPECT and SPECT/CT evaluation and diagnosis in cardiac diseases Evaluation and diagnosis of neurological examinations SPECT and SPECT/CT in oncological investigations, evaluation and diagnosis Principles, problems and follow up of radiotherapy, radiation exposure Seminars Exam topics/questions Multiple choice test. Participants Dr. Bódisné Dr. Zámbó Katalin (BOZMAAO.PTE), Dr. Lőrinczy Dénes (LODGAAO.PTE), Dr. Schmidt Erzsébet (SCEMAAO.PTE), Dr. Szabó Zsuzsanna (MOSGABA.PTE), Dr. Szekeres Sarolta (SZSFAFO.PTE) 323 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-KKM COMPLEX PATHOPHYSIOLOGICAL MECHANISMS DR. MÁRTA BALASKÓ, associate professor Department of Pathophysiology and Gerontology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAP-KO2 completed Topic On basis of information from pathophysiology, the pathomechanism and consequences of complex (physiological and/or pathological) functional changes are analyzed, which changes affect several organs and regulatory systems. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Test exam (multiple-choice) at the end of the course. Making up for missed classes Essay from the subject of the omitted lecture. Reading material - Obligatory literature - Literature developed by the Department Lecture slides will be uploaded to CooSpace. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Capsaicin, its receptors, functional role Dr. Garami András Complex energetic insufficiencies Rittmann-né Dr. Pétervári Erika Cold-related disorders Dr. Szekeres-Solymár Margit Comparison of metabolic coma states Dr. Balaskó Márta Alcohol action, alcoholism Rittmann-né Dr. Pétervári Erika Global climatic changes and medicine Dr. Székely Miklós Smoking and air pollution Dr. Balaskó Márta Metabolic syndrome Dr. Soós Szilvia Chronic bed-rest Dr. Szelényi Zoltán Basics of medical diet Dr. Garai János Homocysteic acid, folic acid and health Dr. Garai János Pathophysiology of oxygen therapy Dr. Soós Szilvia Pathophysiology of low/high atmospheric pressure Dr. Székely Miklós Test exam Dr. Balaskó Márta 324 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions Test-exam Participants 325 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-KOE CASE-REPORTS: PATHOPHYSIOLOGICAL ANALYSES DR. MÁRTA BALASKÓ, associate professor Department of Pathophysiology and Gerontology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 25 Prerequisites: OAP-KO2 completed Topic Analysis of case-reports in various topics, all from the aspect of pathophysiology (background, interactions, etc.) in an interactive way (discussions). Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Analysis of a written case-report at the end of the course. Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department Selected case histories will be uploaded to CooSpace. - Notes - Recommended literature EC Toy, JT Patlan, F Faustinella, SE Cruse (eds.): Case Files Internal Medicine, Lange Medical Book McGraw-Hill, New York 2007 EC Toy, BC Simon, KY Takenaka, B Baker, TH Liu (eds.): Case Files Emergency Medicine, Lange Medical Book McGraw-Hill, New York 2005 EC Toy, RJ Yetman, RG Girardet, MD Hormann, SL Lahoti, MC McNeese, MJ Sanders (eds.): Case Files Pediatrics, Lange Medical Book McGraw-Hill, New York 2010 Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Case-reports: cardiovascular diseases I Case-reports: cardiovascular diseases II Problems in hematology Trauma cases Acute respiratory disorders Chronic respiratory disorders Case-reports: gastrointestinal disorders Pancreatic and hepatic disorders Toxicoses I Toxicoses II Case-reports: disorders of the intermediary metabolism I Case-reports: disorders of the intermediary metabolism II Case-studies: endocrine disorders I Case-studies: endocrine disorders II Exam topics/questions None Participants Dr. Balaskó Márta (BAMMAAO.PTE), Dr. Garai János (GAJMAAO.PTE), Dr. Garami András (GAAFAEO.PTE), Dr. Soós Szilvia (SOSSAAI.PTE), Dr. Székely Miklós (SZMGAEO.PTE), Dr. Szekeres-Solymár Margit (SOMFAAO.PTE), Rittmann-né Dr. Pétervári Erika (PEEFAAO.PTE) 326 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-PSA PSYCHOSOMATIC APPROACH IN MEDICINE DR. ISTVÁN TIRINGER, assistant professor Department of Behavioural Sciences Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 15 Prerequisites: OAP-MT5 completed Topic Psychosomatic medicine examines the definition, constructs, and dilemmas that confront professionals working at the interface of medicine and psychiatry, psychosomatic medicine, and consultation-liaison psychiatry. Psychosomatic medicine can be described as well as the subspecialty of psychiatry that focuses on medical and psychiatric comorbidity. The course is intended to define key problems of psychosomatic medicine and advise methods of diagnosis and treatment. Conditions for acceptance of the semester Writing a paper about an optional psychosomatic disorder Absence: max. 15% of seminars Examination: Multiple Choice Test Mid-term exams Making up for missed classes Reading material - Obligatory literature Michael Blumenfield, MD, James J. Strain, MD: Psychosomatic Medicine, Lippincott Williams & Wilkins, 2006 ISBN: 0781760461 - Literature developed by the Department CooSpace - Notes - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 1. Introduction 1. Introduction 2. Stress and Disease 2. Stress and Disease 3. Psychological Responses to Illness 3. Psychological Responses to Illness 4. Depression 4. Depression 5. Anxiety Disorders 5. Anxiety Disorders 6. Somatization and Somatoform Disorders 6. Somatization and Somatoform Disorders 7. Heart Disease 7. Heart Disease 8. Gastrointestinal Disorders 8. Gastrointestinal Disorders 9. Oncology 9. Oncology 10. Pain 10. Pain 11. Behavior Change 11. Behavior Change 327 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 23 24 25 26 27 28 12. Palliative Care, Hospice, and Care of the Dying 12. Palliative Care, Hospice, and Care of the Dying 13. Practitioner Well-being 13. Practitioner Well-being 14. Summary 14. Summary Exam topics/questions Psychosomatic Medicine: History of a New Specialty Symptoms: Historical Perspective and Effect on Diagnosis. Diagnostic and Classificatory Dilemmas Depression: A Systemic Illness Evolution of Measurement Implications of Culture Cardiovascular Disease Oncology Gastrointestinal Disease Pulmonary Disease Rheumatoid Diseases Conversion Disorders, Somatization, Hypochondriasis Death and Dying. Pain and Palliative Care Cognitive Behavioral Therapy. Personality Traits and Disorders Participants Dr. Tiringer István (TIIHAAE.PTE) 328 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-TUO SYMPTOM-BASED DIAGNOSTICS IN INTERNAL MEDICINE DR. JÓZSEF CZIMMER, assistant professor 1st Department of Internal Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 7 lectures + 7 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 25 Prerequisites: OAP-BPR completed Topic The subject goals to deal with a very important issue of internal medicine and general practitioners (family doctor’s) praxis, the symptombased and problem-oriented approach to the patients and disorders considering the up-to-date evidences and latest guidelines. We would like to teach a systematic way of thinking and use it in the praxis. The course is based on the systematic discussion of main symptoms, differential diagnostics, to find the adequate information sources and practice them. Some of the information found in textbooks are out of date because of the long lasting process of publications, in the age of internet (even bed-side use is available by smart devices) the immediate knowledge of the latest scientific results is possible in the everyday medical practice, patients of the 21st century are wellinformed from the internet, so the doctors of the present and the future cannot miss this knowledge. Our goal is to teach and enhance evidence-based thinking in medicine and differential diagnostics. 50% of course contains lectures that detail the main symptoms of different disciplines of internal medicine, based on etiological, diagnostic and differential diagnostic approaches using up-to-date guidelines, latest evidences and internationally accepted protocols. We would like to share our experience in the field, as well. 50% of the course contains bed-side practices in small (1-3 persons) groups that are the basis of 2 self-tailored case stories that will be the basis of the credit. Practices are good occasions for use of detailed methods and the immediate feed-back from experts and so enhance the process of learning. We suggest this basic course for every student who are interested in the internal medicine and at least have started propedeutics of internal medicine subject. Conditions for acceptance of the semester Up to 2 absences from classes (15%) are acceptable, fulfil of all practices is mandatory (timing is relatively flexible) and submission of 2 case-based essay, that will be the base of the grade. Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Harrison’s: Principals of Internal Medicine Lectures 1 2 3 4 5 6 7 Anamnesis, family anamnesis, hetero-anamnesis, social anamnesis, drug history, rapid-diagnosis. Cost-effective diagnostics. Diagnostic features of acute severe cases. Dr. Czimmer József Gastroenterological differential diagnostics I. Acute and chronic abdominal pain, dysphagia, weight loss. Dr. Czimmer József Gastroenterological differential diagnostics II. Diarrhea, constipation, nausea, vomiting, jaundice, ascites. Dr. Czimmer József Cardiological differential diagnostics. Chest pain /discomfort/ syndrome, palpitation. Dr. Kenyeres Péter Cardiological and pulmonological differential diagnostics. Dyspnea, pulmonary edema, cyanosis, hypoxemia, edema, cough, hemoptysis. Dr. Kenyeres Péter Infectological and nephrological differential diagnostics. Fever, hyperthermia, hypothermia, fever of unknown origin. Differential diagnostics of skin and soft tissue infections. Dr. Kappéter Ágnes Hematological differential diagnostics. Anemia, polycythemia, hemophilia, thrombosis, lymph node disorders, white blood cell disorders. Dr. Czimmer József 329 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices 1 2 3 4 5 6 7 Evidence-Based Medicine. Effective Internet-Based Searching Techniques and Practice. Part I. (József Czimmer MD PhD) Evidence-Based Medicine. Effective Internet-Based Searching Techniques and Practice. Part II. (József Czimmer MD, PhD) Gastroenterological differential diagnostics: bed-side practice in small groups. Cardiological differential diagnostics: bed-side practice in small groups. Infectological differential diagnostics: bed-side practice in small groups. Hematological, nephrological, pulmonological differential diagnostics: bed-side practice in small groups. Summary of the course. Consultation based on the submitted case-based essays. (József Czimmer MD, PhD) Seminars Exam topics/questions Participants Dr. Czimmer József (CZJFAAO.PTE), Dr. Kappéter Ágnes (KAAFADO.PTE), Dr. Kenyeres Péter (KEPFACO.PTE) 330 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-DEP ANXIETY, DEPRESSION AND SOMATIZATION IN GENERAL MEDICAL PRACTICE DR. JÓZSEF VARGA, assistant professor Department of Behavioural Sciences Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 0 lectures + 14 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 16 Prerequisites: OAP-MT5 completed Topic Anxiety and depression symptoms are often unrecognised and left without therapy as doctors usually focus on somatic problems. Somatization - a common set of functional somatic symptoms -poses a diagnostic challenge for the physician. This course overviews the features and therapeutic approaches of these problems in the general practice. Presenting the interaction of affective conditions and biological diseases, offers a behavioural concept in the medical practice. Conditions for acceptance of the semester According to the Code of Studies and Examinations. Mid-term exams Making up for missed classes Additional practices and homework. Reading material - Obligatory literature - Literature developed by the Department Hand-outs, publications presented at the practices. - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Affective and cognitive functions of personality, stress, health and illness. Affective and cognitive functions of personality, stress, health and illness. Theories, sources and symptoms of anxiety and depression. Psychological risks and their medical consequences. Theories, sources and symptoms of anxiety and depression. Psychological risks and their medical consequences. Recognising of early symptoms of anxiety and depression; prevention, diagnostics. Recognising of early symptoms of anxiety and depression; prevention, diagnostics. Mechanisms of somatization, symptomatology, diagnostics. Mechanisms of somatization, symptomatology, diagnostics. Communication with the somatizing patient, supportive therapy, patient care. Communication with the somatizing patient, supportive therapy, patient care. Cognitive and behavioral therapeutic approaches. Cognitive and behavioral therapeutic approaches. Case studies. Case studies. Seminars Exam topics/questions A topic presentation + final test. Participants Dr. Varga József (VAJGABO.PTE) 331 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-EDM EPIDEMIOLOGICAL METHODS FOR UNDERGRADUATE RESEARCH (TDK) AND THESIS- WRITING DR. ISTVÁN KISS, professor Department of Public Health Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 7 Number of hours/semester: 10 lectures + 18 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 2 – 15 Prerequisites: OAP-NEO completed Topic The medical and pharmacist students get to know those research methods which mean the basis of evidence based medicine. During their undergraduate research and preparing for their thesis they also take part similar studies. The aim of this course is to improve the ability of research planning, implementation, result procession and assessment. The most important practical skills are choosing and implementing the adequate epidemiological methods, the practical usage of SPSS and not the acquirement of the statistical and mathematical background. It can considerably help your scientific work. Conditions for acceptance of the semester Participation in lectures and practicals is obligatory which is registered. Absences should not exceed 15% (4x45 min). Otherwise signature of grade book is denied. Mid-term exams Oral exam, 14th week. Making up for missed classes There are no make-up classes. Reading material - Obligatory literature - Literature developed by the Department Educational material uploaded on CooSpace. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 Basics of epidemiology and research methodology I Dr. Berényi Károly Basics of epidemiology and research methodology II Dr. Berényi Károly Basics of research design Dr. Berényi Károly Ethical questions in scientific work, ethics approval Dr. Berényi Károly Creation of adequate hypothesis Dr. Berényi Károly Design of human studies based on questionnaire Dr. Berényi Károly Design of studies based on quantitative measurements Dr. Berényi Károly Design of studies based on qualitative measurements Dr. Berényi Károly Design of molecular epidemiological studies Dr. Berényi Károly How to present the results Dr. Berényi Károly 332 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 Possibilities and rules of data recording Statistical programs for epidemiological study assessments (Excel, SPSS, R, Statistica etc.) Overview of most frequently used statistical methods Applications of survival models Analysis of screening methods, ROC curve analysis I Analysis of screening methods, ROC curve analysis II Processing questionnaires Analysis and assessment for attitude experiments Basics of factor-analysis and interpretation of results I Basics of factor-analysis and interpretation of results II Multivariate analysis in epidemiology I Multivariate analysis in epidemiology II Evaluation of multivariate analysis Evaluation of association and cause-effect relationship Analysis of epidemiological studies. Computer practical I Analysis of epidemiological studies. Computer practical II Analysis of epidemiological studies. Computer practical III Analysis of epidemiological studies. Computer practical IV Seminars Exam topics/questions CooSpace Participants Dr. Berényi Károly (BEKFABO.PTE) 333 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-FMA DATA ANALYSIS 1 DR. LÁSZLÓ PÓTÓ, associate professor Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 7 lectures + 7 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 12 Prerequisites: no prerequisites Topic The goal of this course is to help students to prepare for thesis writing or making their own student research project. It covers mainly two fields of that: read and interpret scientific papers and prepare an own study plan. Shortly to say: How to prepare for your own study project. Block One: The medical papers are likely the most important source to improve your present knowledge as a student and as an MD. Most of these „original papers” are based on carefully planned data collection and evaluation applying a wide array of statistical methods. It is essential to be familiar with this methodology so to understand these papers. But you may learn these steps and methods from the papers since all are based on the rules of designing scientific research projects. From a paper you may extract the principles as well as you can follow immediately the realization. It is an excellent way to learn the methodology. You may even learn from the errors. Block Two: Apply all these for your own research: make a study plan. It should include your study goal the extent and way of your data collection the preliminary data processing the way of data analysis and the way of conclusion making. Based on this outline you will prepare your own study design on your own student’s research work or on your thesis job. If you have no such project at the moment you may construct an own „sample study plan” that can be a working model for your future thesis work. You will have all help to find your own project and complete the plan in the practice if you need. All of your personal design elements will be discussed and improved by a class discussion. The practical realization of your study will be supported by the Data analysis 2 course. Conditions for acceptance of the semester Maximum 1 lesson absence Prepare and submit your own study plan based on your active participation. Mid-term exams Active participation, max 1 lesson absence Making up for missed classes One extra class Reading material - Obligatory literature 1-3 medical papers brought by each student (from library, from your department or from the tutor of your thesis). - Literature developed by the Department Other supporting materials supplied by the tutor of the classes. - Notes - Recommended literature Any statistical books on study design and data analysis. Lectures 1 2 3 4 5 6 7 Introduction. Find a paper to process. Find your own study. Dr. Pótó László The goal of your study - based on a demo paper Dr. Pótó László The main- and „sub-”hypotheses of the study. Dr. Pótó László Finding your sample frame - based on your hypotheses. Dr. Pótó László The research design and the methods of the data collection. How many data should be collected? Dr. Pótó László Creating the plan of the data analysis. Dr. Pótó László The complete study plan. Dr. Pótó László 334 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices 1 2 3 4 5 6 7 Introduction. Overview of some sample papers. The goal of your study - processing a few papers brought and presented by students. Setting the study hypotheses. Further analysis of the papers. Which data should you collect and how to do that. Finalize the plan of your data collection. Make a plan of the data processing. Create, present and discuss of your study plan. Seminars Exam topics/questions Preparation of the study plan Participants Dr. Pótó László (POLGABO.PTE) 335 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-FM2 DATA ANALYSIS 2 DR. LÁSZLÓ PÓTÓ, associate professor Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 7 lectures + 7 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 12 Prerequisites: OAF-FMA parallel Topic The goal of this course is to help students to prepare for thesis writing or making their own student research project. It covers two fields of that job: the practice of data collection and prepare data for the analysis as well as the performing the analysis based on the preliminary analysis plan. Shortly to say: How to perform the data collection and analysis of your own study project. (This course can be the continuation of the ‘Data analysis 1’ course however someone can complete these two courses on a reversed order as well. The main reason of this flexibility is, that many students are asking for help when they have already had their data at hands (at least partially), and this course is processing the steps from this point of the job. Even though, it is beneficial for the students doing this course first to complete the Data analysis 1 course later. They can do it next year for example – so to understand the preliminary steps of a research work: How to make a research plan?) This course is also based on the medical papers. Students may pick the appropriate data collection methods and recognize the critical points of this process based on the most fundamental papers of their own research field. They can learn from the most rewarded experts on this way. From a paper you may extract the principles as well as you can follow immediately the realization. It is an excellent way to learn the methodology. You may even learn from the errors. The same way is followed for the data analysis and making conclusions. Every student will do his/her own data analysis based on their own plan. Students will have all help to the practical evaluation of their own data and making the right conclusion. The steps and results will be discussed and improved by a class discussion. Conditions for acceptance of the semester Maximum 1 lesson absence Evaluate your data and submit your own results based on your active participation. Mid-term exams Present your own research results. Making up for missed classes One extra class Reading material - Obligatory literature 1-3 medical papers brought by each student (from library, from your department or from the tutor of your thesis). - Literature developed by the Department Supporting materials (papers, posters, research reports, ...) supplied by the tutor of the classes. - Notes - Recommended literature Any statistical books. Lectures 1 2 3 4 5 6 7 Introduction. Find a paper to process. Prepare or present your own data collection plan. Dr. Pótó László The realization of the data collection - examples are based on papers Dr. Pótó László The preliminary data preparations for the following statistical analysis. Dr. Pótó László Do your own statistical analysis 1 - select the right methods Dr. Pótó László Do your own statistical analysis 2 - interpret the results. Dr. Pótó László Make your conclusion and share the results with the others. Dr. Pótó László Summary. Consolidation and evaluation of the results. Dr. Pótó László 336 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices 1 2 3 4 5 6 7 Find a paper to process. Work on your own data collection plan. Present the realization of the data collection - based on selected papers Share your experiences on your preliminary data preparations - make corrections if needed. Present your own statistical analysis 1 - methods and results 1 Continue - methods and results 2 Make your conclusion and share the results with the others. Overview and summarize the results of the class. Seminars Exam topics/questions Evaluate your data and submit your own results based on your active participation. Participants Dr. Pótó László (POLGABO.PTE) 337 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-GIP CHILD AND ADOLESCENT PSYCHIATRY DR. GYÖRGYI CSÁBI, associate professor Department of Paediatrics Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 7 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 2 – 20 Prerequisites: OAA-AA2 completed + OAP-KO1 completed + OAA-ANT completed Topic The subjects explores child and adolescent psychiatric disorders from a diagnostic and therapeutic perspective. Mental retardation, pervasive disorders, tic disorders, elimination disorders, psychotic disorders, suicide, behavioral problems, anxiety disorders and other psychiatric problems are discussed. Recent psychological and biological theories are introduced. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams No exam Making up for missed classes Essay should be written Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Gillberg C., Harrington R., Steinhausen H.C. (eds.): A Clinicians’ Handbook of Child and Adolescent Psychiatry, Cambridge University Press Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 Mental retardation Dr. Csábi Györgyi Anxiety disorders Dr. Csábi Györgyi Eating disorders Dr. Csábi Györgyi Psychotic disorders Dr. Tényi Tamás Affective disorders Dr. Tényi Tamás Substance use disorder Dr. Csábi Györgyi Personality disorders Dr. Tényi Tamás Pervasive developmental disorder Dr. Csábi Györgyi Somatoform disorders Dr. Csábi Györgyi Physical and sexual abuse Dr. Csábi Györgyi Elimination disorders: enuresis and encopresis Dr. Csábi Györgyi ADHD, TIC disorder Dr. Csábi Györgyi Post-traumatic stress disorder Dr. Csábi Györgyi 338 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 14 Conduct disorder, Specific developmental disorders Dr. Csábi Györgyi Practices Seminars Exam topics/questions Participants 339 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-HTI EFFICIENT THESIS WRITING DR. VALÉR CSERNUS, professor Department of Anatomy Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 7 Number of hours/semester: 12 lectures + 0 practices + 0 seminars = total of 12 hours Course headcount limitations (min.-max.): 3 – 120 Prerequisites: no prerequisites Topic The doctoral thesis is a significant component of the medical degree. Most students, however, has no experience in writing a successful thesis. This course will deal with the fundamentals of thesis writing. The acquired skills will be also beneficial later during your professional life. Several details have to be considered during the process. How do you find a suitable thesis topic? How do you get started? What does a thesis look like? What are the formal requirements? Where can you find scientific publications, and how do you cite them correctly? And how do you defend your thesis for a top grade? These topics are addressed in this course. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Written (score-decisive) test on the last lecture of the semester. Oral retake in the first week of the exam period. Making up for missed classes Consultation after the lecture Reading material - Obligatory literature - Literature developed by the Department The lecture drafts will be available on the WEB page of the Anatomy department (http://an-server.pote.hu/eOkt.htm) - Notes - Recommended literature Code of Studies and Examinations of the PTE (especially Amendment 2) Lectures 1 2 3 4 5 6 7 8 9 10 11 12 General rules and formal requirements of the thesis. Vikjord Sigrid Anna Types of theses. Choosing an appropriate topic and finding a consultant. Preparatory works. Vikjord Sigrid Anna The structure of the thesis Vikjord Sigrid Anna Time management and drafting. Vikjord Sigrid Anna Obtaining relevant background information. Using literature. Use of scientific databases. Search strategies Vikjord Sigrid Anna The writing process. Special considerations of academic writing. Vikjord Sigrid Anna Presentation of the results. Embedding figures, graphs. The principles of statistical analysis. Dr. Csernus Valér Citations. The use of citation software. Vikjord Sigrid Anna Bringing it all together. Vikjord Sigrid Anna Ethical considerations. Plagiarism. Dr. Csernus Valér Defending your thesis. Preparation of convincing presentation documentation. Vikjord Sigrid Anna Summary. Exam. Vikjord Sigrid Anna 340 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions http://an-server.pote.hu/eOkt.htm Participants 341 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-IFZ NEURODEVELOPMENTAL DISORDERS DR. GYÖRGYI CSÁBI, associate professor Department of Paediatrics Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 7 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 2 – 20 Prerequisites: OAP-PA2 completed Topic The subject deals with the disorders of neurodevelopment from a clinical perspective. Introduces the most important aspects of neurodevelopment and shows the clinical and etiopatogenetic characteristics of different neurodevelopmental disorders. Child and adult neurological and psychiatric disorders are described in details. Conditions for acceptance of the semester 20% absence is acceptable. Mid-term exams Making up for missed classes An essay based on literature Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature DSM -5, American Psychiatric Association, 2013 Kaplan Sadock: Synopsis of Psychiatry, 10th edition, Wolters Kluver, 2007 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 The neurobiology of neurodevelopment Dr. Csábi Györgyi Neuropathological and neuroradiological characteristics of neurodevelopmental disorders Dr. Csábi Györgyi Mental retardation I Dr. Csábi Györgyi Mental retardation II Dr. Csábi Györgyi Epilepsy and neurodevelopment Dr. Csábi Györgyi Attention deficit hyperactivity disorder Dr. Csábi Györgyi Neurodevelopment and autism spectrum disorders Dr. Csábi Györgyi Communication disorders, motor disorders, and specific learning disorders Dr. Csábi Györgyi Neurodevelopment and psychopathological models Dr. Tényi Tamás The neurodevelopmental model of schizophrenia I Dr. Tényi Tamás The neurodevelopmental model of schizophrenia II Dr. Tényi Tamás The neurodevelopmental background of mood disorders and OCD Dr. Tényi Tamás The therapy of neurodevelopmental disorders I Dr. Csábi Györgyi The therapy of neurodevelopmental disorders II Dr. Tényi Tamás 342 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions There will not be exam Participants 343 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MIA CURRENT HOT TOPICS IN MEDICAL MICROBIOLOGY DR. LÁSZLÓ SZEREDAY, associate professor Department of Medical Microbiology and Immunology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 50 Prerequisites: OAP-MI1 completed Topic This elective course is aimed at discussing the actual hot topics in the field of medical microbiology. Emphasis will be placed on the prevention, diagnosis and treatment of these infectious diseases. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Personal consultation Making up for missed classes Personal consultation Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Patrick R. Murray: Medical Microbiology, 7th edition, 2013 Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Ebola virus outbreak Dr. Szereday László Ebola virus outbreak Dr. Szereday László Bioterrorism Dr. Szereday László Bioterrorism Dr. Szereday László Fecal microbiota transplantation (C. difficile) Dr. Szereday László Fecal microbiota transplantation (C. difficile) Dr. Szereday László Clinical applications of botox (C. botulinum) Dr. Szereday László Clinical applications of botox (C. botulinum) Dr. Szereday László Measles outbreak linked to Disneyland (Morbilli virus) Dr. Szereday László Measles outbreak linked to Disneyland (Morbilli virus) Dr. Szereday László Top 5 most deadliest infections Dr. Szereday László Top 5 most deadliest infections Dr. Szereday László Flue (bird, swine and human flu) Dr. Szereday László Flue (bird, swine and human flu) Dr. Szereday László 344 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 15 16 17 18 19 20 21 22 23 24 25 26 27 28 TB and its vaccination (M. tuberculosis) Dr. Szereday László TB and its vaccination (M. tuberculosis) Dr. Szereday László Family planning and HIV Dr. Szereday László Family planning and HIV Dr. Szereday László Flesh eating bacterial infections (S. pyogenes) Dr. Szereday László Flesh eating bacterial infections (S. pyogenes) Dr. Szereday László New drugs in Hepatitis C infections Dr. Szereday László Vaccines Dr. Szereday László Superbugs: multidrug-resistant organisms (MRSA etc.) Dr. Szereday László Superbugs: multidrug-resistant organisms (MRSA etc.) Dr. Szereday László New drugs in Hepatitis C infections Dr. Szereday László New drugs in Hepatitis C infections Dr. Szereday László Consultation and exam Dr. Szereday László Consultation and exam Dr. Szereday László Practices Seminars Exam topics/questions See lecture topics Participants 345 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-RAR IMMUNOLOGICAL BASIS OF RHEUMATOID ARTHRITIS (RA) DR. FERENC BOLDIZSÁR, associate professor Department of Immunology and Biotechnology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 7 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 20 Prerequisites: OAP-PA1 completed + OAP-PA2 completed Topic The aim of the course is to introduce the participants with the immunopathological background of rheumatoid arthritis (RA), paying special attention to the potential molecular and cellular mechanisms, beginning from the clinical features. The topics cover the role of Tand B cells, and cytokine regulation in detail. The role of new T cell groups (regulatory T cells and NKT cells) in the pathogenesis of RA will be discussed. Broadening of the „classical cytokine paradigm” (Th1/Th2): „new” cytokines (IL-17, IL-21, IL-23 and IL-27) and their potential role in RA. Complex, side-by-side discussion of experimental data from human RA patients and RA animal models is a central scope of the course. Getting acquainted with the immunological aspects of RA in detail will help the participants in the understanding of modern therapeutical approaches. Conditions for acceptance of the semester Maximum number of absences: 2. Participants will prepare a short talk based on a paper selected by the tutor and related to one of the topics of the seminars. Mid-term exams Making up for missed classes None. Reading material - Obligatory literature - Literature developed by the Department The slides of the seminars will be available on-line on the website of the Department of Immunology and Biotechnology (www.immbio.hu). - Notes - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Introduction, the aim of the course, requirements. Natural and pathologic autoantibodies in the blood of healthy and autoimmune patients, the „immunological homunculus”. Clinical features of RA (ethiology, diagnosis, symptoms) 1. Clinical features of RA (ethiology, diagnosis, symptoms) 2. Cells in the pathomechanism of RA 1. T cells. Cells in the pathomechanism of RA 2. B cells. Cells in the pathomechanism of RA 3. Regulatory T cells. Cells in the pathomechanism of RA 4. NKT cells. Cytokine regulators of RA 1. The classical Th1/Th2 paradigm. Cytokine regulators of RA 2. IL-17 and other „novel” cytokines (IL-21, IL-23, IL-27). Animal models of RA 1. Introduction, groups. Animal models of RA 2. Induced models (proteoglycan-, collagen-, adjuvant-induced arthritis). Animal models of RA 3. Spontaneous models. (IL-1R antagonist knock-out-, SKG mice) Modern therapeutical approaches of RA. Exam topics/questions None. Participants Dr. Boldizsár Ferenc (BOFFAAO.PTE), Dr. Engelmann Péter András (ENPAAA.T.JPTE), Dr. Németh Péter (NEPGAAO.PTE) 346 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-SFO SPECIALTIES IN OTOLARYNGOLOGY DR. JÓZSEF PYTEL, professor Department of Oto-rhino-laryngology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 7 Number of hours/semester: 14 lectures + 14 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 1 – 30 Prerequisites: no prerequisites Topic Specialties, which could not be involved in the regular course. The connection of the cultural civilisation and the ORL Conditions for acceptance of the semester Only two missing lectures are accepted Mid-term exams No exam during semester Making up for missed classes There are no possibilities Reading material - Obligatory literature - Literature developed by the Department - Notes www.peditop.com - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Laryngeal cancer and the literature (Babits, Kosztolányi) Dr. Pytel József Laryngeal cancer and the history (Emperor Friedrich) Dr. Pytel József Laryngeal cancer and the music (Puccini) Dr. Pytel József The hearing and the music (Tartini - Beethoven) Dr. Pytel József Functional esthetic surgery (Otoplasty, Rhinoplasty) Dr. Pytel József Percutan endoscopic Gastrostomy (PEG) Dr. Pytel József Snoring and sleepapnea Dr. Pytel József Borderline in Functional Endoscopic Sinus Surgery (Ophthalmology, neurosurgery) Dr. Pytel József Otoacoustic Emissions Dr. Pytel József Neonatal Hearing Screening Dr. Pytel József Basics of the Acoustically Evoked Potentials Dr. Pytel József Acoustically evoked potentials: ECoG, BERA, CERA, MLR Dr. Pytel József Reconstructions after maior oncological surgery (Miocutan flaps, microvascular flaps) Dr. Pytel József Borderlines in the ENT (Dermatology, General surgery, thyroid gland surgery, Neurosurgery etc.) Dr. Pytel József 347 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Direct laryngoscopy (on larynx of cadaver and pigs) Suture technics, practices on leg of pig Examination of the ear with microscope, Dissection (Drilling) on cadaver temporal bone. Audiological examinations Suture technics under microscopical control Percutan endoscopic Gastrostomy (PEG) (Model-exercises) Snoring and sleep apnea (instruments, aids) Functional Endoscopic Sinus Surgery on cadaver nasal cavity Measurements of Otoacoustic Emissions, TEOAEPlastic flaps and suture technics, Microvascular suture technics Universal Newbornbaby Screening, demonstration Measurements of Acoustic Evoked Potentials Microvascular suture technics Plastic flaps and suture technics Seminars Exam topics/questions It is the same as the list of the lectures. Participants Dr. Pytel József (PYJGAAO.PTE) 348 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-THM THERMOMANIA: THE MEDICINE OF THERMOREGULATION DR. ANDRÁS GARAMI, assistant professor Department of Pathophysiology and Gerontology Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 7 Number of hours/semester: 24 lectures + 0 practices + 0 seminars = total of 24 hours Course headcount limitations (min.-max.): 2– Prerequisites: OAP-KO2 completed Topic Maintenance of normal body temperature means life. Students applying for the course can learn the importance of temperature from the caveman till present days, they will get an insight into the mechanisms maintaining body temperature and into revolutionary theories of thermoregulation. They will hear how certain food ingredients (e.g., chili, menthol, etc.) influence body temperature, how thermoregulation differs between dinosaurs and humans and what are the subcellular heater units of our body. Based on the earned theoretical knowledge, students will then learn about extreme thermoregulatory disorders (e.g., hypothermia in high mountains, hibernation, etc.), furthermore, about the characteristics and peculiarities of the clinical appearance, diagnosis and therapy of thermoregulatory disorders in adult and childhood, in the form of clinical and pathophysiological case studies. Conditions for acceptance of the semester The absence rate is required to be kept under less than 25% of all lectures. At the end of the class students need to pass a multiple choice written test-exam. Mid-term exams Based upon individual agreements. Making up for missed classes Based upon individual agreements. Reading material - Obligatory literature - Literature developed by the Department A. Gomtsyan, C.R. Faltynek: Vanilloid Receptor TRPV1 in Drug Discovery, Wiley & Sons, 2010. www.FeverLab.net - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 The importance of temperature from the caveman till present and beyond. Dr. Garami András Proper techniques of temperature measurements: what should we pay attention to? Dr. Garami András 37 degrees Celsius: mechanisms of body temperature maintenance. Dr. Garami András Revolution in the field of thermoregulation. Dr. Garami András The role of chili, menthol, wasabi, cinnamon and their receptors in temperature regulation. Dr. Garami András Chili-pepper against obesity? Role of the capsaicin receptor in energy balance. Dr. Garami András Temperature maintenance from dinosaurs to humans: the evolution of thermoregulation. Dr. Mátics Róbert Microscopic heating units of the body: heat production in the mitochondria. Dr. Mátics Róbert Feeding, as a heat generator. Dr. Armbruszt Simon Ferenc Hypothermia in high mountains. Dr. Armbruszt Simon Ferenc 349 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Representative clinical cases of thermoregulatory disorders in adults I Dr. Ruzsics István Representative clinical cases of thermoregulatory disorders in adults II Dr. Ruzsics István Common clinical cases of fever in childhood I Dr. Józsa Gergő Common clinical cases of fever in childhood II Dr. Józsa Gergő Peculiar clinical cases of temperature regulation disorders I Dr. Fehér Zsolt Peculiar clinical cases of temperature regulation disorders II Dr. Fehér Zsolt Clinical cases of fever in urology I Dr. Kenyeres Balázs Clinical cases of fever in urology II Dr. Kenyeres Balázs Hotheaded, coldblooded: brain-teasing pathophysiological case studies I Dr. Szekeres-Solymár Margit Hotheaded, coldblooded: brain-teasing pathophysiological case studies II Dr. Szekeres-Solymár Margit Hibernation, hypothermia. Dr. Garami András Thermoregulation and its disorders in the elderly. Dr. Garami András Multiple choice test-exam. Dr. Garami András Multiple choice test-exam. Dr. Garami András Practices Seminars Exam topics/questions Exam topics are the same as the topics of the lectures: 1. The importance of temperature from the caveman till present and beyond. 2. Proper techniques of temperature measurements: what should we pay attention to? 3. 37 degrees Celsius: mechanisms of body temperature maintenance. 4. Revolution in the field of thermoregulation. 5. The role of chili, menthol, wasabi, cinnamon and their receptors in temperature regulation. 6. Chili-pepper against obesity? Role of the capsaicin receptor in energy balance. 7. Temperature maintenance from dinosaurs to humans: the evolution of thermoregulation. 8. Microscopic heating units of the body: heat production in the mitochondria. 9. Feeding, as a heat generator. 10. Hypothermia in high mountains. 11. Representative clinical cases of thermoregulatory disorders in adults I. 12. Representative clinical cases of thermoregulatory disorders in adults II. 13. Common clinical cases of fever in childhood I. 14. Common clinical cases of fever in childhood II. 15. Peculiar clinical cases of temperature regulation disorders I. 16. Peculiar clinical cases of temperature regulation disorders II. 17. Clinical cases of fever in urology I. 18. Clinical cases of fever in urology II. 19. Hotheaded, coldblooded: brain-teasing pathophysiological case studies I. 20. Hotheaded, coldblooded: brain-teasing pathophysiological case studies II. 21. Hibernation, hypothermia. 22. Thermoregulation and its disorders in the elderly. 23. Multiple choice test-exam. 24. Multiple choice test-exam. 350 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Participants 351 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-ATE ANAESTHETIC TECHNIQUES DR. ISTVÁN BÁTAI, associate professor Department of Anaesthesia and Intensive Therapy Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 0 lectures + 0 practices + 12 seminars = total of 12 hours Course headcount limitations (min.-max.): 1 – 25 Prerequisites: OAP-GT1 completed + OAP-KO2 completed Topic This course describes the main anaesthetic techniques (inhalational, intravenous, regional). It also emphasizes the indications, contraindications and complications in the early postoperative period. The aim is to help the non-anaesthetists involved in patient management in the perioperative period. Conditions for acceptance of the semester Maximum 25% absence is accepted. Mid-term exams Making up for missed classes None Reading material - Obligatory literature - Literature developed by the Department Lecture notes. - Notes - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 The pharmacokinetics of total intravenous anaesthesia (TIVA). Drugs used for TIVA Indications, contraindications and complications of TIVA The pharmacokinetics of inhalational anaesthesia Drugs used in inhalational anaesthesia Indications, contraindications and complications of inhalational anaesthesia The anatomy of regional anaesthesia Drugs used in regional anaesthesia Regional anaesthesia - neuraxial block Regional anaesthesia - peripheral nerve blocks of the upper limb Regional anaesthesia - peripheral nerve blocks of the lower limb Intravenous regional anaesthesia (IVRA) Exam topics/questions Participants Dr. Bátai István (BAIMABO.PTE) 352 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-GCT PRACTICAL ULTRASOUND AND CT DIAGNOSTICS DR. ISTVÁN BATTYÁNI, associate professor Department of Radiology Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 15 Prerequisites: OAA-BI2 completed + OAK-KRA completed Topic The course is opened for al of the students who are successfully completed the Clinical Radiology subject. The aim of the course is to get more information and practice on the field of ultrasound and CT techniques. The US practice is focus mainly to the abdominal and vascular examinations, and the students will learn the latest, newest CT technology applications in the clinical practice. During the practice the students have to make examinations by self. Conditions for acceptance of the semester To get the index book signed, a maximum of 2 (two) seminars (4 hours) may be missed and they are not replaceable by any kind. Missed seminars, caused by disease, can be certified by a written certificate obtained from the treating physician (booked in the log of his/her office)! Mid-term exams Making up for missed classes No possibility for the replacement. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature In English: R. B. Gunderman: Essential Radiology, Thieme, 2006 G. M. Roberts, J. P. Hughes, and M. D. Hourihan: Clinical Radiology for Medical Students S. Francis, A. F. Watkinson (Department of Radiology The Royal Free Hospital, London, UK): Interventional Radiology explained, REMEDICINA Publishing, 2000. Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Physics and technical applications of ultrasonography. New development. Ultrasound terminology and US appearance of different pathologic conditions. Liver and biliary ultrasound imaging. Liver and biliary ultrasound imaging in practice. Spleen, pancreas and GI tract US imaging. Spleen, pancreas and GI tract US imaging in practice. Genitourinary system, prostate, adrenal gland US imaging. Genitourinary system, prostate, adrenal gland US imaging in practice. Retroperitoneum, large vessels, peritoneum US imaging. Retroperitoneum, large vessels, peritoneum US imaging in practice. Ultrasound contrast materials. Ultrasound contrast material in practice. Soft tissue, lymphnode, thyroid US imaging. Soft tissue, lymphnode, thyroid US imaging in practice. Musculo-sceletal US imaging. Musculo-sceletal US imaging. Diseases of peripheral vessels and their ultrasound imaging. Diseases of peripheral vessels and their ultrasound imaging in practice. Techniques and new developments of computer tomography. Dual energy imaging in clinical practice. 353 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 21 22 23 24 25 26 27 28 Abdominal CT diagnostics. Abdominal CT diagnostics in practice. Chest CT diagnostics. Chest CT diagnostics in practice. Ultrasound magnetic navigation. Ultrasound practice. Ultrasound practice. Practical exam with test. Seminars Exam topics/questions Practical exam with test. Participants Dr. Battyáni István (BAIHABO.PTE), Dr. Faluhelyi Nándor (FANFAAO.PTE), Dr. Farkas Péter István (FAPFACO.PTE), Dr. Giyab Omar (ABJHAAO.PTE), Dr. Harmat Zoltán (HAZMAAO.PTE), Dr. Járay Ákos (JAAFADO.PTE), Dr. Szukits Sándor (SZSFAIO.PTE) 354 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-GIO ANGIOLOGY DR. GÁBOR RÓBERT KÉSMÁRKY, associate professor 1st Department of Internal Medicine Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 50 Prerequisites: OAP-BPR completed + OAP-KO2 completed Topic This course aims at increasing the awareness and the knowledge on peripheral vascular diseases. Preventive approach has almost been lacked in this field. Life-threatening acute disorders (acute critical limb ischemia, chronic critical limb ischemia, rupture of an aneurysm, dissection), chronic arterial diseases (peripheral arterial occlusive disease, diabetic foot syndrome, Raynaud’s phenomenon), acute and chronic venous problems, lymphatic disorders, congenital malformations, and vasculitis are addressed. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Test. Making up for missed classes Attending the outpatient clinic of angiology. Reading material - Obligatory literature 1. ESC Textbook of Cardiovascular Medicine, 2006/2010. 2. ESC Guidelines - Peripheral arterial diseases, www.escardio.org, 2011. 3. A.-A. Ramelet, M. Perrin, P. Kern, Bounameaux (eds.): Phlebology, 5th edition, Elsevier, 2008. 4. L. Norgren, W.R. Hiatt, J.A. Dormandy, M.R. Nehler, K.A. Harris, and F.G.R. Fowkes on behalf of the TASC II Working Group: Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II), Journal of Vascular Surgery, 2007, 45 (Suppl. S): S5-S67. - Literature developed by the Department Slides of the course will be available in the homepage of the institute: http://aok.pte.hu/en/egyseg/oktatasianyagok/260 - Notes - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Epidemiology, risk factors of peripheral vascular diseases; physical examination, diagnostic procedures Atherosclerotic arterial diseases, Buerger’s disease Life-threatening vascular diseases: Critical limb ischaemia, Aneurysm rupture, Dissections Imaging techniques in vascular diseases, percutaneous interventions Diabetic foot syndrome Raynaud’s disease, Thoracic outlet syndrome Case presentation. Mid-semester-grade, 1st test Vasculitis Acute venous diseases Chronic venous diseases Vascular surgery Vascular malformations, vascular tumors Lymphoedema Mid-semester-grade, 2nd test 355 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Exam topics/questions Participants Dr. Battyáni István (BAIHABO.PTE), Dr. Bíró Katalin (BIKFABO.PTE), Dr. Késmárky Gábor Róbert (KEGFACO.PTE), Dr. Koltai Katalin (KOKFABO.PTE), Dr. Menyhei Gábor (MEGMABO.PTE), Dr. Pécsvárady zsolt (PEZWABP.PTE), Dr. Sebők Judit (SEJFAAO.PTE) 356 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-GLM PRACTICES IN LABORATORY MEDICINE DR. ATTILA MISETA, professor Institute of Laboratory Medicine Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 0 lectures + 14 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAK-KBK completed Topic Short description of the subject: discretionary laboratory analysis of the samples obtained from the human body is indispensable for the exact assessment of the pathophysiological processes in the patients. Also it is of utmost importance for establishing a diagnosis, monitoring the efficacy of treatment and in preventive medical care. Our subject is based on the previous chemical, biochemical, physiological, pathological, clinical biochemistry knowledge and gives a practical guide to learn those basic laboratory tests that all medical students are expected to do and should perform correctly. Conditions for acceptance of the semester Attendance of the practices is obligatory. Absences up to 25% can be accepted. Mid-term exams Making up for missed classes Those absent from a practical lesson can join another group performing the same topics (within the two-week period of the practical lessons) Reading material - Obligatory literature - Literature developed by the Department Written material related to the practices will be handed to the students by the teachers. - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Sample collection and preparation - blood, urine, body fluids Sample collection and preparation - blood, urine, body fluids Microscopic and automated blood picture tests Microscopic and automated blood picture tests Basic and automated tests in blood coagulation and hemostasis Basic and automated tests in blood coagulation and hemostasis Urine analysis (chemical and microscopic testing) Urine analysis (chemical and microscopic testing) Automated clinical chemistry tests Automated clinical chemistry tests POCT (Point of care) - dry chemistry tests and their interpretation POCT (Point of care) - dry chemistry tests and their interpretation Interpretation of laboratory tests Interpretation of laboratory tests Seminars Exam topics/questions Written examination: test questions, based on the practices Participants Dr. Kőszegi Tamás Antal (KOTHAAE.PTE), Dr. Nagy Tamás II (NATFABO.PTE) 357 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-GNU CHILD NEUROLOGY DR. KATALIN OHMACHT-HOLLÓDY, associate professor Department of Paediatrics Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 12 lectures + 12 practices + 0 seminars = total of 24 hours Course headcount limitations (min.-max.): 5 – 20 Prerequisites: OAA-NEA completed + OAA-EL2 completed Topic Diseases of the nervous system in infancy and childhood have a profound impact on the life of patients and their families and are probably the most disruptive of all paediatric ailments. Neurological diseases account for a significant proportion of the serious paediatric diseases, as between 15 and 20 per cent of hospitalized children have a neurological problem. The aim of the course: to give a comprehensive description of the main neurological diseases of children to permit diagnostic orientation, prognosis and management. Conditions for acceptance of the semester Active participation. The attendance of the lectures and practices is compulsory, it will be checked regularly. The maximal permitted number of absences is 2, independently of the reason. Mid-term exams Making up for missed classes Not possible Reading material - Obligatory literature - Literature developed by the Department Slides - Notes - Recommended literature Swaimann, K.F., Ashwal, S., Ferriero, D.M.: Pediatric Neurology. Principles and Practice, 4th ed., Mosby Elsevier, ISBN-13: 9780323033657 Lectures 1 2 3 4 5 6 7 8 9 10 11 The role of inspection in the child neurology Dr. Ohmachtné Dr. Hollódy Katalin Special history taking in the child neurology Dr. Ohmachtné Dr. Hollódy Katalin Normal development of the newborn and young infant Dr. Ohmachtné Dr. Hollódy Katalin Seizures in the childhood Dr. Ohmachtné Dr. Hollódy Katalin Paroxysmal disorders other than epilepsy in childhood Dr. Ohmachtné Dr. Hollódy Katalin Central nervous system injuries Dr. Büki András Neuromuscular disorders Dr. Ohmachtné Dr. Hollódy Katalin Neurosurgery in the infancy and childhood Dr. Dóczi Tamás Movement disorders in the childhood Dr. Ohmachtné Dr. Hollódy Katalin Tumors of the central nervous system Dr. Kajtár Pál Developmental delay in the childhood Dr. Ohmachtné Dr. Hollódy Katalin 358 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 Child with special needs Dr. Ohmachtné Dr. Hollódy Katalin Practices 1 2 3 4 5 6 7 8 9 10 11 12 The role of inspection in the child neurology Neurological examination of the children Neurological examination in and beyond the newborn period Video-EEG demonstration of epileptic seizures Video demonstration of paroxysmal disorders other than epilepsy in childhood Central nervous system injuries Children with neuromuscular disorders Neurosurgery in infancy and childhood Video demonstration of movement disorders Children with CNS tumors Children with mental retardation and cerebral palsy Early intervention Seminars Exam topics/questions Participants Dr. Büki András (BUAMAAO.PTE), Dr. Dóczi Tamás (DOTHAAO.PTE), Dr. Kajtár Pál (KAPMAAO.PTE), Dr. Ohmachtné Dr. Hollódy Katalin (HOKPAAP.PTE) 359 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-KFA CLINICAL PHARMACOLOGY DR. TAMÁS HABON, associate professor 1st Department of Internal Medicine Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 26 lectures + 2 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 25 Prerequisites: OAK-GT3 completed Topic The objectives of this subject are as follows: to help medical students understand the theoretical and practical principles of the rational drug administration, risk in taking drugs, drug interactions, human phases of drug development, its bioetical regulations and patients with special clinical condition that affects the practice of rational therapeutics. In the practical part of the curriculum consultations are organized on the application of frequently used drugs. Conditions for acceptance of the semester Maximum 20% absences can be accepted. Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Melmon and Morelli: Clinical Pharmacology: Basic Principles in Therapeutics. Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Introduction to clinical pharmacology Dr. Habon Tamás Rational pharmacotherapy - Evidence based medicine Dr. Habon Tamás Drug development in humans Dr. Bölcskei Kata Good Clinical Practice Dr. Bölcskei Kata Applied pharmacokinetics: therapeutic drug monitoring, pharmacotherapy in special patient populations Dr. Bölcskei Kata Original and generic drugs Dr. Bölcskei Kata Management of chronic pain Várbiróné Dr. Csikós Ágnes Other palliative pharmacotherapy Várbiróné Dr. Csikós Ágnes Pharmacotherapy in infectious disorders 1 Dr. Péterfi Zoltán Pharmacotherapy in infectious disorders 2 Dr. Péterfi Zoltán Pharmacological management of cardiovascular risk factors Dr. Bajnok László Zoltán Dyslipidemia, Diabetes, Obesity Dr. Bajnok László Zoltán Ischemic heart disease Dr. Koltai Katalin Arrhythmias Dr. Koltai Katalin Heart failure Dr. Habon Tamás 360 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 16 17 18 19 20 21 22 23 24 25 26 Hypertension Dr. Habon Tamás Therapy in thrombotic disorders 1 Dr. Késmárky Gábor Róbert Therapy in thrombotic disorders 2 Dr. Késmárky Gábor Róbert Pharmacotherapy in GI diseases Dr. Czimmer József Pharmacotherapy in hepatic or pancreatic diseases Dr. Czimmer József Bronchial asthma Dr. Illés Miklós Balázs COPD Dr. Illés Miklós Balázs Pharmacotherapy in rheumatic or immunologic diseases 1 Dr. Czirják László István Pharmacotherapy in rheumatic or immunologic diseases 2 Dr. Czirják László István Drug side effects Dr. Hunyady Béla Drug interactions Dr. Hunyady Béla Practices 27 28 Seminars in practical pharmacotherapy. Case-studies in drug use Test exam Seminars Exam topics/questions Participants Dr. Habon Tamás (HATMAAO.PTE) 361 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-NKD MODERN CARDIOVASCULAR DIAGNOSTICS AND THERAPY DR. RÓBERT HALMOSI, associate professor 1st Department of Internal Medicine Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 150 Prerequisites: OAP-BPR completed + OAP-KO2 completed + OAP-GT2 parallel Topic The main educational task of the subject: To approach the cardiac diseases, that are important in the everyday medical practice, from the viewpoint of the general medical and clinical practice. To introduce the most important diagnostic and therapeutic procedures. Characteristics, diagnostic value of non-invasive cardiologic diagnostic procedures. Introduction into the practical skills needed to independently perform these tests. State of the art pharmacological and non-pharmacological therapy in the prevention and treatment of cardiovascular diseases. Conditions for acceptance of the semester Two written tests during the semester. Mid-semester-grade. Two absences (4 hours) are tolerated during the semester at the seminars. More than two absences result in automatic exclusion. Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department First Department of Medicine lecture slides http://www.pote.hu/index.php?page=egyseg&egy_id=260&menu=okt_anyag&nyelv=eng - Notes - Recommended literature Braunwald, E., Zipes, D. P., Libby, P., Bonow, R. O.: Braunwald Heart Disease. A Textbook of Cardiovascular Medicine, W. B. Saunders Company, 2008 Houghton AR, Gray D: Making Sense of the ECG - A hands-on guide Camm A.J, et al.: ESC Textbook of Cardiovascular Medicine, 2006 Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Introduction. ECG-based examinations (ECG analysis, Exercise stress testing, Holter monitoring, Transtelephonic ECG, Heart rate variability, signal-averaged ECG) Introduction. ECG-based examinations (ECG analysis, Exercise stress testing, Holter monitoring, Transtelephonic ECG, Heart rate variability, signal-averaged ECG) Echocardiography (TTE, TEE, stress echo, contrast echo, 3D echo) Echocardiography (TTE, TEE, stress echo, contrast echo, 3D echo) Nuclear cardiology (hybrid cardiac imaging, SPECT, PET) Nuclear cardiology (hybrid cardiac imaging, SPECT, PET) Genetics of cardiovascular diseases Principles of laboratory diagnostics in cardiology, biomarkers Cardiac CT and MRI Interim exam (ECG analysis) Pulmonary embolism. Pulmonary arterial hypertension. Pulmonary embolism. Pulmonary arterial hypertension. Acute heart failure Acute heart failure Actual problems in the treatment of stable angina pectoris Actual problems in the treatment of stable angina pectoris 362 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 17 18 19 20 21 22 23 24 25 26 27 28 Acute coronary syndromes Acute coronary syndromes Emergency treatment of cardiac rhythm disorders Emergency treatment of cardiac rhythm disorders Critical limb ischemia Critical limb ischemia Treatment of resistant hypertension Treatment of resistant hypertension Pregnancy and heart disease Pregnancy and heart disease Role of multicenter clinical studies in the cardiological diagnostics and therapy Written test (MCQ) Exam topics/questions Participants Dr. Bódisné Dr. Zámbó Katalin (BOZMAAO.PTE), Dr. Czopf László József (CZLMAAO.PTE), Dr. Habon Tamás (HATMAAO.PTE), Dr. Halmosi Róbert (HARFABO.PTE), Dr. Késmárky Gábor Róbert (KEGFACO.PTE), Dr. Márton Zsolt I (MAZFABO.PTE), Dr. Nagy Lajos (NALPAAP.PTE), Dr. Szabados Eszter (SZEMAAO.PTE), Dr. Tóth Kálmán (TOKGAAO.PTE) 363 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-OIN MEDICAL INFORMATICS DR. LÁSZLÓ PÓTÓ, associate professor Institute of Bioanalysis Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 7 lectures + 7 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 1 – 18 Prerequisites: OAA-MET completed Topic Medical Informatics is a multidisciplinary topic Storage. database indexing, sampling (Shannon), data compression, encryption, modeling, biometric identification, highlighting the essence, image processing and interpretation, evaluation of EEG and ECG signals, filters, neural networks, learning systems, expert systems, patient management, BNO code. The goal is: not only to accept and apply the new methods and results but be able to understand the common basics and use them for further developments. Conditions for acceptance of the semester Max 2 lessons absent Mid-term exams Last week: A short test for refreshing the most important topics. Making up for missed classes One extra class, one consultation possible Reading material - Obligatory literature - Literature developed by the Department On a CD - Notes - Recommended literature On the CD Lectures 1 1 2 3 4 5 6 7 The topics of medical Informatics, a historical overview, constraints of development and chances to break through Dr. Pótó László The topics of medical Informatics, a historical overview, constraints of development and chances to break through Dr. Pótó László Basic concepts of Information, sampling, digitalization, coding Dr. Pótó László Security issues, handling of personal data, data search, indexing Dr. Pótó László Application aspects of data compression Dr. Pótó László Modeling processes, system controls Dr. Pótó László Intelligent signal processing in medical praxis Dr. Pótó László Expert systems, summary overview Dr. Pótó László Practices 1 2 3 4 5 6 7 Examples for the lecture topics, Structure of a motherboard Examples for the lecture topics, Examples for the lecture topic, Demonstration of some data compression methods Examples of control-systems: stability and dynamics Presentation of some diagnostic applications Application of biofeedback method in therapy, closing test 364 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Last week: A short test for refreshing the most important topics. Participants Dr. Pótó László (POLGABO.PTE) 365 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-POF PROBLEM-BASED PHARMACOLOGY DR. ZSUZSANNA HELYES, associate professor Department of Pharmacology and Pharmacotherapy Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 0 lectures + 0 practices + 24 seminars = total of 24 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAK-GT3 completed Topic The subject aims at presenting and discussing problematic cases from different areas of the clinical practice. The students can develop their skills to solve difficulties in clinical situations, learn practical aspects of pharmacotherapy, get familiar with the latest clinical guidelines, disease-drug and drug-drug interactions, indications and counter-indications, as well as side-effect profiles. Conditions for acceptance of the semester Written exam (multiple choice test and assay questions) 25% of the total number of classes Mid-term exams None. Making up for missed classes Not possible. Reading material - Obligatory literature None. - Literature developed by the Department PowerPoint slides available on the intranet. - Notes None. - Recommended literature Golan D.E., Tashjian A.H. Jr, Armstrong, E.J., Armstrong, A.W. (eds.): Principles of Pharmacology, The Pathophysiologic Basis of Drug Therapy, 2nd edition, Wolters Kluwer Health, Lippincott Williams and Wilkins 2008. Farrel S.E., Ed. Golan D.E.: Principles of Pharmacology, workbook, Wolters Kluwer Health, Lippincott Williams and Wilkins 2008. Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 Problems of the pharmacotherapy of cardiovascular diseases 1 Problems of the pharmacotherapy of cardiovascular diseases 2 Pharmacotherapy of gastrointestinal diseases 1 Pharmacotherapy of gastrointestinal diseases 2 Problems of the pharmacotherapy of airway diseases 1 Problems of the pharmacotherapy of airway diseases 1 Problems affecting coagulation disorders and their treatment Pharmacotherapy of haemathological diseases Problems in the pharmacotherapy of critically ill patients Pharmacological problems in anaesthesiology Drug treatment during pregnancy Special problems in the pharmacotherapy of children Problems of the pharmacotherapy of neurological and psychiatric patients 1 Problems of the pharmacotherapy of neurological and psychiatric patients 2 Treatment of inflammatory diseases 1 Treatment of inflammatory diseases 2 Pharmacological problems in analgesic therapy 1 Pharmacological problems in analgesic therapy 2 366 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 19 20 21 22 23 24 Problems with antimicrobial therapy 1 Problems with antimicrobial therapy 2 Special pharmacological problems in oncology Special pharmacological problems in metabolic diseases- diabetes Special pharmacological problems in metabolic diseases: obesity, metabolic syndrome Pharmacological problems in endocrine diseases Exam topics/questions None. Participants Dr. Pozsgai Gábor (POGFAAO.PTE), Sánticsné Dr. Pintér Erika (PIEMAAO.PTE), Tamasikné Dr. Helyes Zsuzsanna (HEZFAAO.PTE) 367 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-TRO TROPICAL MEDICINE DR. ZOLTÁN PÉTERFI, associate professor 1st Department of Internal Medicine Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 20 Prerequisites: no prerequisites Topic Because of the extent tourism and migration rare imported tropical diseases are common all over the world. The knowledge of prevention, clinical symptoms and differential diagnostic issues of tropical diseases is useful to every physician because misdiagnosis or the lack of therapy can threat the patient’s life. The course involve travel medicine issues as well. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Test at the end of the semester Making up for missed classes Not possible Reading material - Obligatory literature - Literature developed by the Department Slides of lectures - Notes - Recommended literature Manson’s Tropical Diseases, twenty-second edition Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Preparing for travel Dr. Feiszt Zsófia Preparing for travel Dr. Feiszt Zsófia Most common imported tropical diseases Dr. Feiszt Zsófia Viral hemorragic fevers Dr. Feiszt Zsófia Tropical bacterial infections (Thyphoid fever, Cholera, Pest, Bartonellosis) Dr. Feiszt Zsófia Tropical bacterial infections (Thyphoid fever, Cholera, Pest, Bartonellosis) Dr. Feiszt Zsófia Leprosy ant other Mycobacterial infections Dr. Feiszt Zsófia Leischmaniasis Dr. Feiszt Zsófia Schistosomiasis Dr. Feiszt Zsófia African and American Trypanosomiasis Dr. Feiszt Zsófia Non-veneral Treponema infections Dr. Feiszt Zsófia HIV/AIDS Dr. Feiszt Zsófia 368 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Non-infectious tropical diseases Dr. Feiszt Zsófia Malnutrition Dr. Feiszt Zsófia Practices Seminars Exam topics/questions Preparing of travellers Most common imported tropical diseases Viral hemorragic fevers Tropical bacterial infections (Thyphoid fever, Cholera, Pest, Bartonellosis) Leprosy ant other Mycobacterial infections Leischmaniasis Schistosomiasis Non-venereal Treponema infections HIV/AIDS Non-infectious tropical diseases Malnutrition Participants 369 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-ERM VASCULAR SURGERY TECHNIQUES DR. GÁBOR JANCSÓ, associate professor Department of Surgical Research and Techniques Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 0 lectures + 14 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 12 Prerequisites: OAP-MUA completed Topic We advise this course to students interested in surgical lines, to develop their technical skills in the field of vascular surgery. The course is suggested to students interested in surgery, vascular surgery, traumatology, urology, and cardiac surgery. In the course the students learn about the instruments and basic techniques of vascular surgery, pre-and postoperative treatments of vascular surgery patients. The different arterial suture techniques can be practiced on skill models and preparatums: opening and closing of cross and lengthwise arteriotomies, arterial patch plastics, and arterial anastomosis will be prepared. The endovascular techniques will be introduced. During the clinical operating room practices students see and take part in vascular reconstruction operations as assistants. Conditions for acceptance of the semester According to the Code of Studies. Mid-term exams Making up for missed classes Attendance is obligatory at every practice. Reading material - Obligatory literature - Literature developed by the Department http://soki.aok.pte.hu/ - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Instruments of vascular surgery, arterial suture techniques on models Instruments of vascular surgery, arterial suture techniques on models Cross and lengthwise arteriotomies, closing with direct suture on models Cross and lengthwise arteriotomies, closing with direct suture on models Lengthwise arteriotomies with patch plastic Lengthwise arteriotomies with patch plastic Preparing end-to-side arterial anastomosis on models Preparing end-to-side arterial anastomosis on models Endovascular techniques (balloon dilatation, stent implantation) Endovascular techniques (balloon dilatation, stent implantation) Clinical practice in operation theatre: arterial reconstruction surgery Clinical practice in operation theatre: arterial reconstruction surgery Clinical practice in operation theatre: endovascular techniques Clinical practice in operation theatre: endovascular techniques Seminars Exam topics/questions http://soki.aok.pte.hu/ Participants Dr. Hardi Péter (HAPFAAO.PTE), Dr. Jancsó Gábor (JAGMAAO.PTE), Dr. Nagy Tibor Aladár (NATIAAO.PTE) 370 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-FBJ DENTAL AND ORAL DISEASES IN GENERAL MEDICINE DR. ÁGNES BÁN, assistant professor Dept. of Dentistry, Oral-, Maxillofacial Surgery Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 15 Prerequisites: OAP-KO2 completed + OAP-MI2 completed + OAP-PA2 completed Topic Oral health is an integral part of general health. It means that there is a mutual relationship between dental and oral mucosal diseases and systemic disorders of the human body. The majority of focal infections have dental origin. Periodontal disease affects diabetes, osteoporosis, cardiovascular diseases, inflammatory bowel diseases, preterm birth, and these conditions have a strong influence on the severity of periodontal disease as well. The oral mucosa is a sensitive indicator of several skin and internal diseases, oral lesions may precede systemic manifestations and symptoms. The aim of this subject is to give a detailed overview of these interrelations. We highly recommend the subject to all future general practitioners, dermatologists, internal medicine physicians and surgeons. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams A written assignment on the 14th week of the semester. Making up for missed classes No possibility. Reading material - Obligatory literature Lecture notes, handouts. - Literature developed by the Department - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Clinical anatomy of the oral cavity, the structure and function of periodontium Dr. Mandel Iván Microbiology of the oral cavity, bacterial and viral infections Dr. Mandel Iván Focal infections of dental origin Dr. Mandel Iván Cardiovascular diseases and the oral cavity Dr. Mandel Iván Diseases of the neuroendocrine system and metabolism and their oral symptoms Dr. Mandel Iván Oral manifestations of HIV infection, the prevention of nosocomial infections Dr. Mandel Iván Diabetes mellitus Dr. Mandel Iván Precancerous lesions Dr. Mandel Iván Vesiculobullous diseases Dr. Mandel Iván Immunological disorders Dr. Mandel Iván Drug related oral lesions Dr. Mandel Iván Gastrointestinal diseases Dr. Mandel Iván 371 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Lichen planus Dr. Mandel Iván Osteoporosis and the oral cavity Dr. Mandel Iván Practices Seminars Exam topics/questions Participants 372 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-GTH GENE THERAPY DR. GÉZA SÁFRÁNY, visiting professor Institute of Laboratory Medicine Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 20 Prerequisites: no prerequisites Topic We wish to give a short overview about the present state of gene therapy, the current ongoing clinical trials and the potential side effects of gene therapy and about the ethical considerations. The various viral and non-viral gene delivery protocols suitable for high efficiency gene delivery both under in vitro and in vivo conditions will be discussed in details. Gene therapy protocols applied in the treatment of malignant diseases will be presented together with the results of ongoing clinical trials. We will talk about the results and the potentials of the treatments of inherited genetic disorders. One of the most promising field of the current clinical trials is the treatment of ischemic diseases, the results will be presented. The potential applications of stem cells during gene therapy will be described, as well. Finally, we will discuss the side effects occurring during gene therapy and the ethical considerations will also be mentioned. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes Joining later seminars, individual consultations. Reading material - Obligatory literature 1. Kelly K. Hunt, Stephan A. Vorburger and Stephen G. Swisher (ed.): Gene Therapy for Cancer, 2007 Humana Press Inc. 999 Riverview Drive, Suite 208 Totowa, New Jersey 07512 2. Thomas F. Kresina (ed.): Introduction to Molecular Medicine and Gene Therapy, 2001 by Wiley-Liss, Inc. ISBNs: 0-471-391883 (Hardback); 0-471-22387-5 (Electronic) - Literature developed by the Department 1. Sáfrány G.: A génterápia génsebészeti alapjai és jelenlegi helyzete, A Genom (ed.: Hídvégi EJ), Budapest, Széphalom Könyvműhely 2003, pp 187-204 Sáfrány G.: A vasculáris génterápia és a csontvelőőssejt-terápia, Atherosclerosis (ed.: Császár A.), Budapest, Synergo Kiadó, 2004 pp 336-344 2. - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 Introduction to gene therapy, ongoing clinical trials Dr. Sáfrány Géza Gene delivery protocols, viral vectors applied in gene therapy Dr. Sáfrány Géza Targeted gene delivery and targeted gene expression Dr. Miseta Attila Gene therapy of HIV Dr. Sáfrány Géza Application of dendritic cells in gene therapy Dr. Sáfrány Géza Gene directed enzyme pro-drug therapy of malignant diseases Dr. Sáfrány Géza Immune therapy of malignant diseases Dr. Sáfrány Géza Radiation-driven gene therapy of malignant disease Dr. Sáfrány Géza Stem cells in gene therapy Dr. Sáfrány Géza 373 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 10 11 12 13 14 Treatment of immune-deficiencies with gene therapy Dr. Sáfrány Géza Gene therapy of ischemic diseases Dr. Sáfrány Géza Gene therapy of cystic fibrosis Dr. Miseta Attila Gene therapy of thalassemia Dr. Sáfrány Géza Oncolytic viruses in tumor therapy Dr. Sáfrány Géza Practices Seminars Exam topics/questions Multiple choice tests for checking the acquisition of course material is given at the end of semester. Questions include material discussed in lectures and seminars. Participants 374 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-HAS ABDOMINAL SURGERY TECHNIQUES DR. GÁBOR JANCSÓ, associate professor Department of Surgical Research and Techniques Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 0 lectures + 14 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 2 – 12 Prerequisites: OAP-MUA completed Topic We advise this course to students interested in surgical lines to develop their technical skills in the field of abdominal surgery. We suggest this course to students interested in surgery, traumatology, urology, gynaecology. Students learn about the instruments and basic techniques of abdominal surgery, pre-and postoperative treatments of surgical patients. The different bowel anastomosis suture techniques, appendectomy, diverticulectomy, cholecystectomy, and hernioplasty can be practiced on skill models. During the clinical operating room practices students can observe and take part as assistants in abdominal operations. Conditions for acceptance of the semester According to the code of studies. Mid-term exams Making up for missed classes Attendance is obligatory at every practice. Reading material - Obligatory literature - Literature developed by the Department http://soki.aok.pte.hu - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Instruments of abdominal surgery, forms of laparatomy and their closing Instruments of abdominal surgery, forms of laparatomy and their closing Forms of bowel sutures, transverse suture on skill model Forms of bowel sutures, transverse suture on skill model Appendectomy, diverticulectomy on skill model Appendectomy, diverticulectomy on skill model Preparing bowel anastomosis on models Preparing bowel anastomosis on models Preparing cholecystectomy and hernioplasty on models Preparing cholecystectomy and hernioplasty on models Clinical practice in operation theatre: colon surgery Clinical practice in operation theatre: colon surgery Clinical practice in operation theatre: cholecystectomy, and hernioplasty Clinical practice in operation theatre: cholecystectomy, and hernioplasty Seminars Exam topics/questions http://soki.aok.pte.hu Participants Bognár Laura (BOLOAA-O.PTE), Dr. Hardi Péter (HAPFAAO.PTE), Dr. Jancsó Gábor (JAGMAAO.PTE), Dr. Nagy Tibor Aladár (NATIAAO.PTE), Dr. Takács Ildikó (TAIFAAO.PTE) 375 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-IOH FORENSIC MEDICINE: NEW CHALLENGES - MODERN FRONTIERS DR. ZSOLT KOZMA, assistant professor Department of Forensic Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 0 lectures + 0 practices + 25 seminars = total of 25 hours Course headcount limitations (min.-max.): 5 – 20 Prerequisites: OAP-PA2 completed Topic Number of medical and non-medical professional disciplines and knowledge should had been integrated into the the forensic medicine in the past, because it was the method that ensure reliable expert assistance for forensic authorities. In the 20th century, numerous subfields detached from this area of science and turned into an independent speciality: e.g. anthropology, toxicology, genetics, psychiatry However, in this 21st century, new integration process of those and other different disciplines can be observed again into the forensic medicine Many modern examples, case studies will be presented during the course. Conditions for acceptance of the semester Mid-term exams None Making up for missed classes Based on personal discussion Reading material - Obligatory literature - Literature developed by the Department On the CooSpace - Notes On the CooSpace - Recommended literature On the CooSpace Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 The role of the intra and interdisciplinarity in the modern forensic medical science: concepts, examples The role of the intra and interdisciplinarity in the modern forensic medical science: concepts, examples The new dimensions of the penal law and the compensation right I: quackery - homeopathy - natural and alternative „medical” applications: legal dilemmas (case studies) The new dimensions of the penal law and the compensation right I: quackery - homeopathy - natural and alternative „medical” applications: legal dilemmas (case studies) The new dimensions of the penal law and the compensation right II: 21st century standards of enforcement efforts in the insurance claim settlements: legal dilemmas (case studies) The new dimensions of the penal law and the compensation right II: 21st century standards of enforcement efforts in the insurance claim settlements: legal dilemmas (case studies) The combined technical and medical experts’ (biomechanical) analyses of road accidents: The PC-Crash 10.0: The Windows based collision & trajectory simulation tool The combined technical and medical experts’ (biomechanical) analyses of road accidents: The PC-Crash 10.0: The Windows based collision & trajectory simulation tool Forensic informatics: The relationship of mobile applications and the forensic medical science with practical examples Forensic informatics: The relationship of mobile applications and the forensic medical science with practical examples Forensic medical science and radiology: the role of modern imagery methods in the report of the permanent impairment Forensic medical science and radiology: the role of modern imagery methods in the report of the permanent impairment Forensic medicine and the infectology: nosocomial infections and legal aspects Forensic medicine and the infectology: nosocomial infections and legal aspects Introduction to Forensic Genetics and Comparative Forensic Medicine Introduction to Forensic Genetics and Comparative Forensic Medicine 376 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 17 18 19 20 21 22 23 24 25 Forensic genetic applications in criminology: the most famous solved crimes of the past decades Forensic genetic applications in criminology: the most famous solved crimes of the past decades The role of the medical science in the modern military genetic applications (practical examples) The role of the medical science in the modern military genetic applications (practical examples) Functional genomics: investigation of coding sequences and the possible medico-legal applications Functional genomics: investigation of coding sequences and the possible medico-legal applications Forensic (genetic) anthropology Forensic (genetic) anthropology Written test Exam topics/questions Participants Dr. Kozma Zsolt (KOZEAC.K.JPTE) 377 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MIS LAPAROSCOPIC SURGERY TECHNIQUES DR. GÁBOR JANCSÓ, associate professor Department of Surgical Research and Techniques Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 0 lectures + 14 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 12 Prerequisites: OAP-MUA completed + OAP-SPR parallel Topic For the safe use of laparoscopic technique specific skills are needed that can be achieved by practicing. The aim of the course is to augment the theoretical knowledge and manual skills of the students interested in minimal invasive surgery. Conditions for acceptance of the semester According to the Code of Studies. Mid-term exams Making up for missed classes Attendance at every practice is obligatory. Because of the limited capacity of our operating theatre absence cannot be solved by joining another group. Reading material - Obligatory literature - Literature developed by the Department http://soki.aok.pte.hu/ - Notes - Recommended literature Lectures Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Acquirement of hand-eye coordination. Thematic exercises on pelvitrainer. Acquirement of hand-eye coordination. Thematic exercises on pelvitrainer. Practicing of laparoscopic preparation in pelvitrainer. Practicing of laparoscopic preparation in pelvitrainer. Practicing of laparoscopic extracorporal knotting technique in pelvitrainer. Practicing of laparoscopic extracorporal knotting technique in pelvitrainer. Practicing of laparoscopic intracorporal knotting technique in pelvitrainer. Practicing of laparoscopic intracorporal knotting technique in pelvitrainer. Laparoscopic cholecystectomy on isolated organs in pelvitrainer. Laparoscopic cholecystectomy on isolated organs in pelvitrainer. Laparoscopic cholecystectomy on anesthetized animal. Laparoscopic cholecystectomy on anesthetized animal. Video assisted thoracic surgery: instruments and technique on anesthetized animal. Video assisted thoracic surgery: instruments and technique on anesthetized animal. Seminars Exam topics/questions http://soki.aok.pte.hu/ Participants Bognár Laura (BOLOAA-O.PTE), Dr. Hardi Péter (HAPFAAO.PTE), Dr. Jancsó Gábor (JAGMAAO.PTE), Dr. Nagy Tibor Aladár (NATIAAO.PTE), Dr. Takács Ildikó (TAIFAAO.PTE) 378 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-REG MEDICAL REHABILITATION AND PHYSICAL MEDICINE; BASICS OF THEORY AND THE DAILY PRACTICE DR. PÉTER CSERHÁTI, associate professor Department of Rehabilitation and Physical Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 14 lectures + 14 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 4 – 80 Prerequisites: no prerequisites Topic Medical rehabilitation and physical medicine; basics of theory and the daily practice The rehabilitation medicine is based on a holistic and comprehensive approach to medical care for individuals who have experienced different kinds of disability resulting from an injury, disease process or developmental disorder. The rehabilitation process uses an interdisciplinary team of health care professionals to help a person to reach their fullest physical, psychological, social, vocational, avocational, and educational potential consistent with his or her goals and life plans. This course of medical rehabilitation focuses on the theoretical and practical knowledge in medical rehabilitation. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams Short test exam Making up for missed classes As agreed with the course director Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Barnes MP, Ward AB. Textbook of Rehabilitation Medicine. Oxford University Press, Oxford, 2005. www.who.int/classifications/icf/en Journal of Rehabilitation Medicine - http://www.medicaljournals.se/jrm/content/ White Book on Physical and Rehabilitation Medicine in Europe Grant Cooper: Essential Physical Medicine and Rehabilitation Lectures 1 2 3 4 5 6 Basic philosophy of rehabilitation (definition, legal background, the ICF-concept of disability, epidemiology of disability) Special features of medical rehabilitation (multi-disciplinarity, functional approach) Dr. Cserháti Péter Institutional system of rehabilitation. Rehabilitation in the scope of in-patient, day-time-hospital, out-patient care and in general practice. Demonstration: rehabilitation of children (Dr. Vekerdy-NagyZsuzsanna) Dr. Aszmann Mária Functional assessment, evaluation, follow-up (movement, communication, behaviour, self-care, limitations in the activities of daily living). Demonstration: rehabilitation post severe brain injury (Dr. Dénes Zoltán) Dr. Péley Iván Rehabilitation team, team work (the role of the medical doctor, psychologist, speech therapist, musical therapist, conductor, teacher of special education, physiotherapist, occupational therapist, nurse, orthopaedic technician in the team). Demonstration: rehabilitation post limb and pelvic trauma and operations. (Dr. Vén Ildikó) Dr. Péley Iván Rehabilitation goals, preparing plans (evaluation of physical loadability, importance of the constructed and the societal environment. Living with a wheel-chair). Demonstration: rehabilitation post severe spinal cord injury (Dr. Klauber András) Dr. Cserháti Péter Programmes of care in rehabilitation. Demonstration: rehabilitation in neurological conditions; stroke Dr. Vajdáné Dr. Tasnádi Emese 379 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 7 8 9 10 11 12 13 14 Assessment of the quality of life. Accessible environment, prevention of immobilization. Demostration: rehabilitation of patients with degenerative and inflammatory peripheral joint diseases Dr. Sarlós Gézáné Interventions in rehabilitation I. (physico-physiotherapy, sport therapy, hydrotherapy, occupational therapy). Demonstration: rehabilitation of patients with degenerative and inflammatory spinal diseases (Dr. Boros Erzsébet, Dr. Nusser Nóra) Dr. Sarlós Gézáné Interventions in rehabilitation II. (prescription of medical aids, adaptation, supply with orthotics and prosthetics, changing of lifestyle). Demonstration: rehabilitation of patients with dysmelia and post amputation. (Dr. Farkas Péter) Dr. Sarlós Gézáné Interventions in rehabilitation III. (robot mediated treatment, neuromodulation and stimulation, application of medicines, infiltration techniques, reconstructive operations). Demonstration: rehabilitation of patients with gastroenterologict diseases in elderly patients. (Dr. Fazekas Gábor, Dr. Kovács Noémi) Dr. Sarlós Gézáné Special points in rehabilitation for elderly patients. Demonstration: rehabilitation after osteoporotic vertebral and hip fractures (Dr. Montskó Péter) Dr. Cserháti Péter Physiology of loading, spiro-ergometry, early rehabilitation of patients with acute cardiologic diseases, in peri-operative conditions. Demonstration: rehabilitation of patients with cardiologic diseases Dr. Szabados Eszter Pulmonary rehabilitation. Physiology of loading, rehabilitation of patients with respiratory diseases. Demonstration: rehabilitation of patients with respiratory diseases. (Dr. Lovász Orsolya) Dr. Nyárfás Géza Autonomy and compliance. Societal approach and acceptance of disability. Basic conception of social, educational and vocational rehabilitation. (Dr. Kullmann Lajos) Demonstration: rehabilitation of patients with psychiatric diseases and addiction (Dr. Szikszai Petronella) Dr. Sarlós Gézáné Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Special features of medical rehabilitation (multi-disciplinarity, functional approach) Demonstration: rehabilitation of children Demonstration: rehabilitation post severe brain injury Demonstration: rehabilitation post limb and pelvic trauma and operations Demonstration: rehabilitation post severe spinal cord injury Demonstration: rehabilitation in neurological conditions and stroke Demonstration: rehabilitation of patients with degenerative and inflammatory spinal diseases Demonstration: rehabilitation of patients with degenerative and inflammatory peripheral joint diseases Demonstration: rehabilitation of patients with dysmelia and post amputation Demonstration: rehabilitation after osteoporotic vertebral and hip fractures Demonstration: rehabilitation of patients with gastroenterologict diseases in elderly patients Demonstration: rehabilitation of patients with cardiologic diseases Demonstration: rehabilitation of patients with respiratory diseases Demonstration: rehabilitation of patients with psychiatric diseases and addiction Seminars Exam topics/questions 1. Basic philosophy of rehabilitation 2. ICF-concept of disability 3. Functional assessment, evaluation, follow-up 4. Rehabilitation team, team work 5. Assessment of the quality of life 6. Basics of rehabilitation of patients with cardiologic diseases 7. Autonomy and compliance. 8. Societal approach and acceptance of disability. 9. Basic conception of social, educational and vocational rehabilitation Participants Dr. Aszmann Mária (ASMRAAO.PTE), Dr. Cserháti Péter (CSPXXXXX.PTE), Dr. Kovács Noémi (KONIAAO.PTE), Dr. Péley Iván (PEIPADA.PTE), Dr. Sarlós Gézáné (VACPAAP.PTE), Dr. Szabados Eszter (SZEMAAO.PTE), Dr. Vajdáné Dr. Tasnádi Emese (TAEAAA.B.JPTE) 380 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-SUB RADIATION BIOLOGY DR. GÉZA SÁFRÁNY, visiting professor Institute of Laboratory Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ spring semester ▪ recommended semester: 8 Number of hours/semester: 14 lectures + 0 practices + 14 seminars = total of 28 hours Course headcount limitations (min.-max.): 2 – 15 Prerequisites: no prerequisites Topic The course will focus on the better understanding of radiation effects on the whole organisms, tissues and cells, as well as on the cellular causes leading to the death of normal and malignant cells. This helps to understand why a given dose of radiation induces tumors in one case while destroys tumor cells in another case. On the basis of radiobiological knowledge one can develop new therapeutic modalities to improve the survival of cancer patients. Radiation biology helps us to understand how and why ionizing radiation can be used to examine healthy and pathological cell structures and to diagnose and treat various diseases. The aim of radiation therapy is to kill tumor cells without seriously damaging normal tissues. The death of normal cells leading to the development of early and late normal tissue sequels strongly influences the amount of total and fraction doses deliverable to the malignant tissues and by this way the success of radiation therapy. We will describe factors and protocols affecting and suitable to predict radiationinduced reactions in healthy and malignant cells. The effect of dose rate, total- and fraction dose, as well as treatment time on the radiation response of normal and tumor cells will be discussed, too. We will describe in details those new radiotherapy approaches (accelerated-, hyper-fractionated, etc. radiotherapy) which were developed on radiobiological backgrounds. We will discuss those new therapeutic modalities such as gene therapy which can be efficiently combined with radiation therapy. Using up to date methodologies the radiation sensitivity of normal and malignant tissues might be predicted before the onset of radiation therapy and radiation regimens can be adjusted to individual needs. This can improve the survival chances of tumor patients. Finally, we will discuss the radiation protection measures necessary to minimize the damaging effect of ionizing radiation. Conditions for acceptance of the semester In the case of maximum 2 unexcused absences the student is allowed to take the exam. Mid-term exams Making up for missed classes Joining later seminars, individual consultations. Reading material - Obligatory literature Radiation Biology: A Handbook for Teachers and Students. International Atomic Energy Agency, Vienna, 2010; http://www.iaea.org/books - Literature developed by the Department - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 The importance of radiobiology in clinical diagnostics and therapy. Types of ionizing radiation, natural and artificial sources of radiation. Dr. Sáfrány Géza Cellular radiation damages, linear energy transfer and the relative biological effect. Dr. Sáfrány Géza Repair of cellular damages at the cellular level, the effect of dose rate on DNA repair. Dr. Sáfrány Géza The effect of oxygen on the survival of cells, radio-sensitizing agents, bioreductive drugs. Dr. Sáfrány Géza Acute radiobiological injuries in humans and in experimental animal models. Dr. Sáfrány Géza Epidemiology and molecular background of radiation-induced tumors. Dr. Sáfrány Géza Proliferative organization of normal tissues. Dose-effect relationships in normal tissues. Dr. Sáfrány Géza The radiobiological background of fractionated radiotherapy, the importance and application of the linear-quadratic approach in tumor treatment. Dr. Sáfrány Géza 381 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 9 10 11 12 13 14 The role of treatment duration, total and fraction dose in radiotherapy. Dr. Sáfrány Géza Radiobiological principles of low and high-dose rate brachytherapy. Dr. Sáfrány Géza Combined chemo- and radiotherapy. Dr. Sáfrány Géza Gene therapy of malignant tumors: combined modality treatments with radio- chemo- and gene therapy. Dr. Sáfrány Géza Risks of occupational exposure to radiation: dose limit in radiation protection. Dr. Sáfrány Géza Doses and risks in nuclear medicine: diagnostic applications Dr. Bódisné Dr. Zámbó Katalin Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Basics of radio-physics and radiochemistry: dosimetry, radiolysis, formation of free radicals, direct and indirect effects of radiation. Cell death due to ionizing radiation, survival curves. Radio-protective agents. Genetic and fetal effects of ionizing radiation. Molecular biological principles of tumor development. The Chernobil nuclear accident and its consequences. Proliferation of tumor cells, factors influencing tumor development. Early and late side-effects of radiotherapy. Alternative radiotherapeutic applications: accelerated-, hyper- and hypo-fractionated radiotherapy, particle radiations. The risk of repeated radiotherapy. Scientific protocols applied in radiobiology. Targeted and individual tumor therapy, estimating radiosensitivity, predictive assays. Doses and risks in radiology and imaging diagnostics. Doses and risks in nuclear medicine: therapeutic approaches. Exam topics/questions Multiple choice test for checking the acquisition of course material is given at the end of semester. Questions include material discussed in lectures and seminars. It is important to know that part of the material cannot be found in textbooks. Participants Dr. Bódisné Dr. Zámbó Katalin (BOZMAAO.PTE), Dr. Sáfrány Géza (SAGRAAO.PTE) 382 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-CUI CURRENT ISSUES AND NEW SURGICAL TECHNIQUES DR. ANDRÁS GÁBOR VERECZKEI, professor Surgery Clinic Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 9 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 3 – 10 Prerequisites: OAP-PA2 completed + OAP-SPR completed + OAK-SE1 completed Topic The course gives information on recent achievements in surgical technology, techniques and treatment modalities for those who are interested not only in basic medical education and/or are weighing the idea of becoming a surgeon in the future. Conditions for acceptance of the semester Obligatory attendance to all lectures. In case of medically certified absence the credit value of the course can be acknowledged. Mid-term exams Making up for missed classes There is none. Reading material - Obligatory literature - Literature developed by the Department Presentations of the lectures serve as knowledge base - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Interventions on the large bowel Dr. Baracs József Interventions on the large bowel Dr. Baracs József Solid organ transplantation Dr. Kalmár Nagy Károly Solid organ transplantation Dr. Kalmár Nagy Károly Actualities in breast surgery Dr. Zapf István Tamás Actualities in breast surgery Dr. Zapf István Tamás Surgical treatment of endometriosis Dr. Orbán Lajos Surgical treatment of endometriosis Dr. Orbán Lajos Curiosities in plastic surgery Dr. Zapf István Tamás Curiosities in plastic surgery Dr. Zapf István Tamás New trends in vascular surgery Dr. Szakály Péter New trends in vascular surgery Dr. Szakály Péter Bariatric surgery Dr. Vereczkei András Gábor SILS, and NOTES Dr. Vereczkei András Gábor 383 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Hepatobiliary surgery Dr. Kalmár Nagy Károly Hepatobiliary surgery Dr. Kalmár Nagy Károly Pancreatic surgery Dr. Kelemen Dezső Tamás Pancreatic surgery Dr. Kelemen Dezső Tamás Actualities in thoracic surgery Dr. Szántó Zalán János Actualities in thoracic surgery Dr. Szántó Zalán János Imaging diagnostics in thoracic surgery Dr. Szalai Gábor Imaging diagnostics in thoracic surgery Dr. Szalai Gábor Novelties in esophageal cancer surgery Dr. Papp András Novelties in esophageal cancer surgery Dr. Papp András New achievements in the treatment of benign oesophageal disorders Dr. Papp András New achievements in the treatment of benign oesophageal disorders Dr. Papp András Hernia surgery Dr. Baracs József Hernia surgery Dr. Baracs József Practices Seminars Exam topics/questions None. Participants 384 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-GEP BASIC PRACTICAL PRINCIPLES OF JOINT REPLACEMENT DR. PÉTER THAN, professor Department of Orthopaedics Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 9 Number of hours/semester: 7 lectures + 18 practices + 0 seminars = total of 25 hours Course headcount limitations (min.-max.): 1 – 10 Prerequisites: OAK-ORT completed Topic One of the main fields of modern orthopedics today is replacement of major joints. Aim of this course is to present basic practical knowledge of this field and to give detailed and high level information to the students. The course is mainly practice oriented. Besides this theoretical principles are discussed as well. History of joint arthroplasty, surgical techniques, indicational criteria, rehabilitation and basic biomechanical principles are presented in lectures. Main factors of practical education are participation in outpatient work, participation in surgical activities (hip and knee prostheses) and observation of rehabilitation of operated patients. Main goal of the education is that students should improve their practical knowledge on the field of patient care. Conditions for acceptance of the semester Maximum 20 % of missed practices and classes allowed. Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department Lecture notes - Notes - Recommended literature 1. Callaghan JJ, Rosenberg AG, Rubash HE: The Adult Hip, Vol. I-II., Lippincott-Raven 2006 2. Callaghan JJ, Rosenberg AG, Rubash HE, Simonian PT, Wiczkiewicz TL: The Adult Knee, Vol. I-II., Lippincott-Raven 2003 Lectures 1 2 3 4 5 6 7 History of artificial joints Dr. Than Péter Prosthesis types Dr. Than Péter Indicational criteria Dr. Than Péter Surgical techniques Dr. Than Péter Results of rehabilitation methods Dr. Than Péter Treatment of complications Dr. Than Péter Future of joint replacement Dr. Than Péter Practices 1 2 3 4 5 6 7 8 9 Types of prostheses, indication, patient selection Types of prostheses, indication, patient selection Types of prostheses, indication, patient selection Cemented hip arthroplasty, surgical participation Cemented hip arthroplasty, surgical participation Cemented hip arthroplasty, surgical participation Uncemented hip arthroplasty, surgical participation Uncemented hip arthroplasty, surgical participation Uncemented hip arthroplasty, surgical participation 385 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 10 11 12 13 14 15 16 17 18 Unicondylar knee prosthesis, surgical participation Unicondylar knee prosthesis, surgical participation Unicondylar knee prosthesis, surgical participation Total condylar knee prosthesis, surgical participation Total condylar knee prosthesis, surgical participation Total condylar knee prosthesis, surgical participation Patient care and rehabilitation on the ward Patient care and rehabilitation on the ward Patient care and rehabilitation on the ward Seminars Exam topics/questions Participants Dr. Than Péter (TAPHAAE.PTE) 386 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-HTK ADVANCED LEVEL TRAUMATOLOGY MANUAL SKILL COURSE DR. NORBERT WIEGAND, associate professor Department of Traumatology and Hand Surgery Course director: 0 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 9 Number of hours/semester: 4 lectures + 8 practices + 2 seminars = total of 14 hours Course headcount limitations (min.-max.): 4 – 12 Prerequisites: OAK-TRA completed + OAA-NEA completed + OAP-SPR completed Topic The aim of the course is to improve the participants’ surgical manual skills in the field of traumatology. Therefore, the course would focus not only on the theoretical knowledge, but also on the manual practice of advanced surgical procedures. The level of knowledge is expected to be achieved by the end of the course exceeds the standards of 4th year basic traumatology curriculum. As preparation to the course, all participants are expected to learn the online available pre-course teaching materials. In the first part of the course, students will learn the indication and then, manually practice different types of special cast fixation techniques. As part of the manual skill practice, participants will exercise the application of casts with special indication (Bennett-, Desault- and Böhler-cast, splinting after Achilles-tendon injury, etc.). Participants could also exercise the use of up-to-date fiberglass and thermoplastic fixation methods. During the second part of the course, participants will learn the up-to-date operative management of excessive, contaminated soft tissue injuries. Attendees to the course exercise the step-by-step operative management of damaged, contaminated soft tissue injuries (wound cleaning, excision of damaged tissue, preparation layer-by-layer into the full depth of the artificial wound, reconstruction of viable elements) on porcine extremity. Additionally, course participants will be able to practice the partial coverage of the remaining soft tissue defect by (skin) flap transposition. Importantly, the opportunity of manual practice will be provided to all participants of the course. Conditions for acceptance of the semester Since the course requires the knowledge of basic principles of plaster fixation and certain manual skills, such as the basics of wound treatment, therefore, the requirement for application to the course is the successful accomplishment of 4th year traumatology exam. Mid-term exams Basic requirement is the interactive participation in the whole duration of the course and successful achievement of the written and practical exam following the first and the second part of the course as well. Absence: Total of 2 hours of absence is allowed during the lectures and seminars, absence from the practical exercises is not allowed. Making up for missed classes In case of absence, there is no other opportunity to accomplish the practical exercises and the participant needs to repeat the course to acquire the credits for it. Reading material - Obligatory literature Oxford Handbook of Orthopaedics and Trauma (Oxford Medical Handbooks) - Literature developed by the Department Online pre-course material - Notes - Recommended literature Campbell’s Operative Orthopaedics, 12th edition, Elsevier Green’s Operative Hand Surgery, Elsevier http://www.aotrauma.org http://www.aaos.org Lectures 1 2 3 4 History of conservative fracture treatment. Indications and limitations of special types of cast fixation methods. Dr. Wiegand Norbert Detailed presentation of modern cast fixation techniques. Application of braces and ortheses. Dr. Nőt László Gergely Principles of wound treatment. Therapeutic principles of wounds with contamination and excessive soft tissue damage. Dr. Patczai Balázs Management of excessive soft tissue defects. Preparation of different type of flaps. Dr. Lázár István 387 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices 1 2 3 4 5 6 7 8 Practical exercise of basic cast fixation techniques. Demonstration of ‘tricks and tips’. Practice of the application of special cast types I. (Deasult-, Böhler-, Bennett-cast, etc) Practice of the application of fiberglass and thermoplastic cast fixation methods. Written (multiple choice test, 25 questions) and practical exam (application of cast) Practical exercise of the basics of wound treatment on porcine extremity. Practice of the management of contaminated wounds with excessive soft tissue damage. Treatment of soft tissue defects with preparation of flaps (Wolfe-Krauze flap) on porcine extremity. Written (multiple choice test, 25 questions) and practical exam (treatment of contaminated wounds) Seminars 1 2 Discussion of the personal and technical means for the application of special cast fixation techniques. Demonstration of the application of fiberglass and thermoplastic cast fixation methods. Discussion of the personal and technical means for the up-to-date management of injuries with excessive soft tissue damage. Demonstration of special surgical tools Exam topics/questions The written exam (multiple choice test with 25 questions) is based on the teaching material of the lectures and seminars. The practical exam contains: after the first part: application one of the previously practiced cast types (Bennett-, Desault-, Böhler-cast, splinting after Achilles-tendon injury, etc.) and after the second part: demonstration of the precise surgical management of a contaminated, damaged wound on porcine extremity. On both practical exams, the score will be determined by a committee formed of 3 lecturers of the course. Participants Dr. Kungl Jusztina (KUJHAAO.PTE), Dr. Lázár István (LAITAC0.PTE), Dr. Nőt László Gergely (NOLFAAO.PTE), Dr. Pankaczi Zsófia (PAZHAAO.PTE), Dr. Patczai Balázs (PABFADO.PTE), Dr. Szabó Tamás (SZTFAMO.PTE), Dr. Wiegand Norbert (WINPAAP.PTE) 388 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-OES ENDOSCOPIC SURGERY OF THE NASAL CAVITIES AND PARANASAL SINUSES DR. IMRE GERLINGER, professor Department of Oto-rhino-laryngology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 9 Number of hours/semester: 10 lectures + 2 practices + 2 seminars = total of 14 hours Course headcount limitations (min.-max.): 2 – 30 Prerequisites: no prerequisites Topic The aim this course is to show the technical aspects of functional endoscopic sinus surgery, the anatomical and pathophysiological changes of sino nasal diseases with cadaver practise and video demonstrations. Conditions for acceptance of the semester Missing of one lectures accepted Mid-term exams During semester no exams Making up for missed classes No possibility Reading material - Obligatory literature - Literature developed by the Department - Notes Simmens -Jones: Endoscopic Sinus Surgery, Thieme - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 Pathophysiology and classification of chronic rhinosinusitis Dr. Gerlinger Imre Anatomy and development of the sinuses Dr. Gerlinger Imre Anamnestic data, patient selection, medical treatment, indication of endoscopic sinus surgery. Who is not proper candidate for surgery? Dr. Gerlinger Imre Role of CT in diagnosis, preoperative checklist, CT/MR differential issues Dr. Gerlinger Imre Role of nasal endoscopy in out-patient practice (presentation of nasal endoscopy) Dr. Gerlinger Imre Step-by-step guidance of endoscopic sinus surgery Dr. Gerlinger Imre Anaesthesia, instrumentation, computer guided surgery, postoperative management Dr. Gerlinger Imre Diagnosis and treatment of facial pain. Mild and serious complications of endoscopic sinus surgery Dr. Gerlinger Imre Further endoscopic operations in rhinosurgery: DCR, ligation of the sphenopalatine artery, frontal sinus surgery, orbital decompression, decompression of the optic nerve, invert papilloma, choanal atresia, scull base surgery Dr. Gerlinger Imre Further endoscopic operations in rhinosurgery: DCR, ligation of the sphenopalatine artery, frontal sinus surgery, orbital decompression, decompression of the optic nerve, invert papilloma, choanal atresia, scull base surgery Dr. Gerlinger Imre Practices 11 12 Successful surgery, persistent symptoms. Which are the further therapeutic possibilities? Management of bleeding in endoscopic sinus surgery 389 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars 13 14 Videodemonstration of endoscopic procedures Application of lasers in rhinosurgery Exam topics/questions www.ent.pote.hu Participants Dr. Gerlinger Imre (GEIOAA-K.PTE) 390 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-ORS SPECIALITIES IN ORTHOPAEDICS DR. PÉTER THAN, professor Department of Orthopaedics Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 9 Number of hours/semester: 14 lectures + 14 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 10 Prerequisites: OAP-PA2 completed + OAK-ORT completed + OAK-SE1 completed Topic The aim is to provide a comprehensive knowledge of different musculoskeletal disorders with special emphasis on their impact on quality of life and recent developments in their treatments. Conditions for acceptance of the semester Maximum of 25 % absence allowed Mid-term exams Making up for missed classes Absence from practices can be redeemed in case the time of the practice does not interfere with other practices and lectures. Redeem can be completed under the circumstances of regular practices. Absences from up to two practices can be redeemed with other groups, but require confirmation. Reading material - Obligatory literature Mark D Miller: Review of Orthopedics, Saunders, 2004 John Crawford Adams, David L. Hamblen: Outline of Orthopaedics, Churchill Livingstone, 2001 Dr. Szendrői Miklós: Az ortopédia tankönyve, Semmelweis Kiadó, Budapest 2005. - Literature developed by the Department Előadások jegyzete - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 Limb equalisation, alternatives in the treatment of cerebral palsy Dr. Than Péter Orthopaedic conditions modifying the quality of life Dr. Than Péter Conservative treatment in orthopaedic conditions. Errors, malpractice Dr. Than Péter Tissue transplantation in orthopedics Dr. Than Péter Sports surgery, arthroscopy, treatment options Dr. Than Péter Cartilage biology, cartilage repair options Dr. Than Péter Inflammatory orthopedic conditions; frontiers in orthopedics Dr. Than Péter Practices 1-14 Physical examination, practice Seminars Exam topics/questions Participants Dr. Antal Hunor (ANHGAAO.PTE), Dr. Bogyó Csaba (BOCTAA0.PTE), Dr. Tunyogi Csapó Miklós (TUCEAA.K.JPTE), Dr. Vermes Csaba (VECFAAO.PTE) 391 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-PTS MANAGEMENT OF SEVERELY INJURED PATIENTS - SIMULATION-BASED CLINICAL SKILLS PRACTICE DR. NORBERT WIEGAND, associate professor Department of Traumatology and Hand Surgery Course director: 0 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 9 Number of hours/semester: 3 lectures + 8 practices + 3 seminars = total of 14 hours Course headcount limitations (min.-max.): 4 – 12 Prerequisites: OAA-NEA completed + OAP-SPR completed + OAK-TRA completed Topic The aim of the course is to practice the ATLS (Advanced Trauma Life Support)-based management of severely injured patients. The level of knowledge is expected to be achieved by the end of the course exceeds the standards of 4th year basic traumatology curriculum. As preparation to the course, all participants are expected to learn the online available pre-course teaching materials. As part of the initial lectures and seminars, the current ATLS-guidelines, the pre-hospital and ICU management of severely injured patients will be presented in details. In collaboration with the MediSkillsLab, during the practical exercises, participants will be utilizing the computer-assisted mannequins for polytrauma „scenarios” to practice the teamwork and the „Ac-B-C-D-E” - based ATLS therapeutic and decision making protocol. The simulation-based clinical skills practice will provide further opportunities, such as exercising chest-tube insertion, arterial or vein cannulation, urinary catheterization, ECG-reading, etc. Importantly, the opportunity of manual practice will be provided to all participants of the course. Conditions for acceptance of the semester The requirement for application to the course is the successful accomplishment of 4th year traumatology exam. Mid-term exams Basic requirement is the interactive participation in the whole duration of the course and successful achievement of the written and practical exam at the end of the course. Absence: Total of 2 hours of absence is allowed during the lectures and seminars, absence from the practical exercises is not allowed. Making up for missed classes In case of absence, there is no other opportunity to accomplish the practical exercises and the participant needs to repeat the course to acquire the credits for it. Reading material - Obligatory literature The Advanced Trauma Life Support? (ATLS?) Student Course Manual - Literature developed by the Department Online pre-course material - Notes - Recommended literature Oxford Handbook of Orthopaedics and Trauma, Oxford Medical Handbooks Campbell’s Operative Orthopaedics, 12th edition, Elsevier Green’s Operative Hand Surgery, Elsevier http://www.aotrauma.org http://www.aaos.org Lectures 1 2 3 Management of severely injured patients. ATLS Dr. Wiegand Norbert Pathomechanism and treatment of hypovolemic shock Dr. Nőt László Gergely Treatment of severely injured patients at the ICU. SIRS, MODS Dr. Rendeki Szilárd 392 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices 1 2 3 4 5 6 7 8 Simulation-based clinical skills practice of the treatment of polytrauma patients; as an active member of the „trauma-team”. Simulation-based clinical skills practice of the treatment of polytrauma patients; as an active member of the „trauma-team”. Simulation-based clinical skills practice of the treatment of polytrauma patients; as an active member of the „trauma-team”. Simulation-based clinical skills practice of the treatment of polytrauma patients; as an active member of the „trauma-team”. Simulation-based clinical skills practice of the treatment of polytrauma patients; as an active member of the „trauma-team”. Simulation-based clinical skills practice of the treatment of polytrauma patients; as an active member of the „trauma-team”. Preparation to the practical exam. Written (multiple choice test, 25 questions) and practical exam (performance as a member of the „trauma-team”. I Preparation to the practical exam. Written (multiple choice test, 25 questions) and practical exam (performance as a member of the „trauma-team”. II Seminars 1 2 3 Introduction of the MediSkillsLab. Demonstration of the Lab’s equipment and the use of the computer-assisted mannequins. Polytrauma case demonstration I. Discussion of the importance of teamwork. Polytrauma case demonstration II. Preparation to the clinical skill practices. Exam topics/questions The written exam (multiple choice test with 25 questions) is based on the teaching material of the lectures and seminars. During the practical exam, students’ performance as „team-member” in a polytrauma scenario will be scored. The score will be determined by a committee formed of 3 lecturers of the course. Participants Dr. Kungl Jusztina (KUJHAAO.PTE), Dr. Lázár István (LAITAC0.PTE), Dr. Nőt László Gergely (NOLFAAO.PTE), Dr. Pankaczi Zsófia (PAZHAAO.PTE), Dr. Patczai Balázs (PABFADO.PTE), Dr. Rendeki Szilárd (RESGABA.PTE), Dr. Wiegand Norbert (WINPAAP.PTE) 393 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-SUO EMERGENCY MEDICINE DR. ZSÓFIA VERZÁR, associate professor Department of Emergency Medicine Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 9 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 150 Prerequisites: OAK-KAR completed + OAK-TRA completed + OAR-ELS completed Topic It is a basic requirement to initialize the aspect of proper emergency care for those who do not take part in emergency medicine. The aim is getting closer to the purpose of care, decrease of avoidable death rates, prevention of organ failure, avoidance of disability, relief of suffering and pain. Conditions for acceptance of the semester Test exam. Mid-term exams Making up for missed classes Personal communication with the tutors. Reading material - Obligatory literature R. Aghababian: Essentials of Emergency Medicine, 2nd edition - Literature developed by the Department - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Basic Life Support - Adult Life Support, Paediatric Life Support Dr. Verzár Zsófia Disaster Medicine Dr. Sütő Balázs Cardiovascular diseases Dr. Horváth Iván Gábor Cardiovascular diseases Dr. Horváth Iván Gábor Abdominal and gastroenterological emergency care Dr. Sütő Balázs Emergency care in neurology Dr. Komoly Sámuel Acute psychiatric disorders Dr. Fekete Sándor Paediatric emergency care Dr. Molnár Dénes Surgical emergencies Dr. Vereczkei András Gábor Trauma care Dr. Nőt László Gergely Burns Dr. Csontos Csaba Toxicology Dr. Bóna Ernő Toxicology, environmental diseases Dr. Bóna Ernő Respiratory, renal diseases, urogenital and obstetric emergencies Dr. Sütő Balázs 394 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions Website of Emergency Medicine, University of Pécs. Participants 395 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-SUP EMERGENCY PSYCHIATRY DR. TAMÁS TÉNYI, professor Department of Psychiatry and Psychotherapy Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ autumn semester ▪ recommended semester: 9 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 130 Prerequisites: OAK-GT3 completed Topic The subject deals with emergency psychiatric issues in clinical practice and consultative psychiatry. Aggressive behavior associated with psychotic and organic cases are explored, as well as the clinical challenge of the dealing with the suicidal patient. Conditions for acceptance of the semester According to the Code of Studies and Examinations Mid-term exams Making up for missed classes According to the Code of Studies and Examinations Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Kaplan Sadock: Synopsis of Psychiatry Lectures 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Summary Dr. Tényi Tamás Biological therapies Dr. Tényi Tamás Symptoms and emergency Dr. Tényi Tamás Psychotherapies Dr. Tényi Tamás Forensic issues Dr. Tényi Tamás Internal and neurological disorders and emergency Dr. Tényi Tamás Addiction and emergency Dr. Fekete Sándor Suicide II. Dr. Fekete Sándor Emergency psychiatry Dr. Tényi Tamás Pregnancy and psychiatric emergency Dr. Tényi Tamás Consultation Dr. Tényi Tamás Suicide I. Dr. Fekete Sándor Aggressive patient Dr. Tényi Tamás Organic psychiatry and emergency Dr. Tényi Tamás 396 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Practices Seminars Exam topics/questions Participants 397 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-FHB OTOLOGY AND TEMPORAL BONE DISSECTION DR. LÁSZLÓ LUJBER, associate professor Department of Oto-rhino-laryngology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 9 Number of hours/semester: 8 lectures + 4 practices + 2 seminars = total of 14 hours Course headcount limitations (min.-max.): 1–2 Prerequisites: OAA-AA1 completed Topic The aim this course is to teach the students the different anatomical and pathological aspects of the ear diseases and surgical techniques. During the course theoretical and practical presentations and demonstrations will be conducted and the students will have the possibility to perform hands-on cadaver dissection on real temporal bones. Conditions for acceptance of the semester Missing of one lectures accepted Mid-term exams No midterm exams needed. Making up for missed classes No possibility Reading material - Obligatory literature - Literature developed by the Department - Notes Harold Ludman and Tony Wright (eds.): Diseases of the Ear, 6th edition, R.A. Jahrsdoerfer, J. Helms (eds.): Head and Neck Surgery, volume 2 - Recommended literature Becker, Naemann, Pfaltz: Ear, Nose and Throat Diseases Lectures 1 2 3 4 5 6 7 8 Anatomical and functional aspects of the external, middle and inner ear Dr. Lujber László Diseases and treatment of the external ear Dr. Lujber László Middle ear diseases I Dr. Lujber László Middle ear diseases II Dr. Lujber László Treatment of the middle ear diseases Dr. Lujber László Myringoplasty Dr. Lujber László Tympanoplasty Dr. Lujber László Reconstruction of the ossicular chain. Dr. Lujber László Practices 1 2 3 4 Temporal bone dissection I Temporal bone dissection II temporal bone dissection III Temporal bone dissection IV Seminars 1 2 Inner ear pathologies and their treatment. Cochlear implantation. 398 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Exam topics/questions www.ent.pote.hu Participants Dr. Lujber László (LULPAAP.PTE) 399 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-MUE MIGRATION HEALTH AND TRAVEL MEDICINE DR. GÁBOR TERNÁK, professor Department of Operational Medicine Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ both semesters semester ▪ recommended semester: 9 Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 30 Prerequisites: OAP-BPR completed + OAP-MI1 completed + OAP-MI2 completed Topic Migration is a rapidly growing global phenomenon. The number of foreign born people within the EU 25 is estimated as high as 50 million. Addressing migrant health goes beyond issues of differing morbidity profiles and vaccination status linked to country of origin or potential for spreading diseases, such as SARS, MDR TB, or tropical diseases. Health and social assistance tailored to migrants needs is also essential, serving their smooth and successful integration with clear social and economic benefit. Public health safety, human rights and health impact of transcultural aspects should be equally addressed. EU external Schengen borders are increasingly exposed to irregular migration. The number of victims of trafficking (the new white slavery) is estimated to hundreds of thousands yearly in the EU. They are seriously abused physically, sexually and psychically. Their proper care and treatment needs specially prepared staff. The health-related issues of an increasing number of tourists traveling the world for business and leisure further require attention to questions of protection and avoidance of health hazards. Doctors must develop appropriate knowledge of the clinical signs and symptoms of the most common infections in the topics, like malaria, dengue fever, etc. Lack of knowledge in this regard may risk the life of the patients. The curriculum is turning the attention to and provides the basic knowledge and skills for answering the need generated by the rapidly growing number of migrants and tourists who may appear and ask for assistance at any level of the health care system Europe wide. Recognizing rare diseases, providing proper medical assistance for travellers and migrants is a priority aim of this curriculum while it helps also in coping successfully with intercultural, inter-religious problems and their health impact and understanding well the human rights angle of the successful integration of migrants. Conditions for acceptance of the semester Participation in 80% of the lessons Mid-term exams Making up for missed classes Individual consultation with the lecturers Reading material - Obligatory literature - Literature developed by the Department Manson: Tropical Diseases World Migration Report 2005, IOM Geneva The Mental Health Aspects of Trafficking in Human Beings, training manual, IOM Budapest The IOM Handbook on Direct. Assistance for Victims of Trafficking, IOM Geneva - Notes - Recommended literature Lectures 0 0 0 0 Mass migration. Factors inducing/ generating mass migration. Temporary placement of refugees and securing their health care. How can the proper health assistance facilitating the successful integration of regular and labour migrants: tasks and programs. Development and implementation of ‘migrant friendly’ health services. (Prof. Tit. Istvan Szilard MD, PhD) Dr. Szilárd István Specific health hazards of different geographic regions. Asia, Africa, South- and Central America, Oceania, Australia, Polar regions Dr. Feiszt Zsófia Environmental factors. Extreme warm and cold climatic effects, health problems caused by altitude (mountaineering) and high pressure (diving), caisson disease. Health insurance of tourists; ensuring return of tourists with health problems. (Dr. Peter Felkai PhD) Dr. Ternák Gábor General overview. Current migration and travel trends world wide. Historical overview. Push and pull factors influencing migration trends. Large populations on move; conditions and consequences. (Prof. Tit. Istvan Szilard MD, PhD) Dr. Szilárd István 400 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 0 0 0 0 0 0 0 0 0 0 Health protection and disease prevention of travellers/ tourists. Clothing, behaviour, general and specific prevention (vaccination, medicines etc.) Dr. Ternák Gábor Human rights and forensic medical aspects of migration and travel. Dr. Szilárd István Irregular migration and its main characteristics. Trafficking and smuggling in human beings, refugees. Health impact of the implementation of the ‘Schengen’ border management procedure. (Prof. Tit. Istvan Szilard MD, PhD) Dr. Szilárd István Travellers with special health conditions. Pregnant women, children, persons with known chronic diseases etc. Dr. Ternák Gábor Food- and water born diseases. Gastrointestinal infections, different types of hepatitis etc. Dr. Ternák Gábor Rare infectious diseases. Tropical parasites, Schistosomiasis, Trypanosomiasis, Leprosy, Plague, Rabies, tropical insects’-, animals’ bite. Dr. Ternák Gábor Irregular migration and related health and public health tasks. Health screenings, most frequent somatic and mental health disorders; ensuring proper placement of irregular migrants; health impact of and coping with cultural differences. Victims of trafficking and their special health care need. (Prof. Tit. Istvan Szilard MD, PhD) Dr. Szilárd István Leading symptoms of diseases acquired during travel/ tourism. Fever, diarrhoea, jaundice/ icterus, rash etc. Dr. Ternák Gábor Vector born diseases. Malaria, Yellow fever, Dengue fever, other haemorrhagic fevers, principle symptoms, possibilities for prevention Dr. Ternák Gábor Health problems related to travel/ tourism. The health-related issues of an increasing number of tourists travelling the world for business and leisure require attention to questions of prevention and protection, avoidance of health hazards, as well as measures to follow in case of illness. Jet leg. (Dr. Peter Felkai PhD) Dr. Ternák Gábor Practices Seminars Exam topics/questions 1/ Current migration trends and their public health impact in Europe 2/ Travel and tourism related environmental factors 3/ Health hazards related with travel and tourism. Special health insurance conditions 4/ Special health conditions and their excess health hazards during travels 5/ Special health hazards of different geographic regions 6/ Preparations for travel related health hazards and possibilities in risk reduction 7/ Food and water born infections 8/ Vector born diseases 9/ Rare diseases travellers/ tourist may be infected with 10/ Alarming symptoms of rare diseases returnees may contact the health service 11/ Trends and composition of irregular migration directed towards the European Union 12/ Health and public health impact of irregular migration 13/ Migrant friendly health services; their aim and characteristics 14/ Human rights aspects of health care provision for migrants Participants 401 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-SFT EMERGENCY-CASES IN OPHTHALMOLOGY, OPHTHALMOSCOPY DR. LÁSZLÓ BALÁZS VARSÁNYI, assistant professor Department of Ophtalmology Course director: 1 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 9 Number of hours/semester: 2 lectures + 10 practices + 0 seminars = total of 12 hours Course headcount limitations (min.-max.): 2–5 Prerequisites: OAP-PA2 completed + OAK-NE1 parallel Topic The clinical signs, therapies of the emergency-cases in ophthalmology will be discussed. We practice ophthalmoscopy, discuss the significance of optic disc edema, its differential diagnosis and the ophthalmoscopic signs of retinal perfusion defects and retinal detachment. Conditions for acceptance of the semester Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature G. Lang: Ophthalmology, Thieme Lectures 1 2 Emergency cases in ophthalmology Dr. Varsányi László Balázs Emergency cases in ophthalmology Dr. Varsányi László Balázs Practices 1 2 3 4 5 6 7 8 9 10 Ophthalmoscopy Ophthalmoscopy Ophthalmoscopy Ophthalmoscopy Ophthalmoscopy Ophthalmoscopy Ophthalmoscopy Ophthalmoscopy Ophthalmoscopy Ophthalmoscopy Seminars Exam topics/questions Participants Dr. Varsányi László Balázs (VABUAAP.PTE) 402 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAF-SSA CARDIAC AND THORACIC SURGERY ANESTHESIA DR. ANDRÁS VOROBCSUK, assistant professor Heart Institute Course director: 2 credit ▪ midsemester grade ▪ Optional module ▪ autumn semester ▪ recommended semester: 9 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): – Prerequisites: OAA-EL2 completed + OAE-KK2 completed Topic Cardiac anesthesia is a complex and comprehensive field of medicine, incorporating many aspects of the specialties of anesthesiology, cardiology, and cardiac surgery. Monitoring modalities always have been an integral part of the practice and have provided us with data to improve our therapeutic interventions. The lecture is designed to present the different cardiac diseases especially right ventricle failure and their therapies with specific hemodynamic monitoring technics. The course emphasizes today’s expanded role of transesophageal echocardiography (TEE) and other ultrasound techniques in the perioperative period. Conditions for acceptance of the semester Maximum of 15 % absence allowed Mid-term exams At the end of semester will be written test, during semester no exam. Making up for missed classes No way of substitution. The students will get a summary at the end of every lecture. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Kaplan’s Cardiac Anesthesia: The Echo Era Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 Physiology of the heart Physiology of the heart Basics of the hemodynamic Basics of the hemodynamic Cardiac anesthesia Cardiac anesthesia Cardiac intensive care Cardiac intensive care Hemodynamic monitoring Hemodynamic monitoring Echocardiography Echocardiography Heart failure Heart failure Myocardial ischemia Myocardial ischemia Coronarography and percutaneous coronary intervention Coronarography and percutaneous coronary intervention Surgical revascularization Surgical revascularization Valve intervention Valve intervention 403 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 23 24 25 26 27 28 Pulmonary hypertension and right ventricle failure Pulmonary hypertension and right ventricle failure Mechanical circulatory support, heart transplantation Mechanical circulatory support, heart transplantation Test Test Exam topics/questions Participants Dr. Vorobcsuk András (VOAGAAO.PTE) 404 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-GYS PAEDIATRIC SURGERY DR. PÉTER VAJDA, assistant professor Department of Paediatrics Course director: 2 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 10 Number of hours/semester: 0 lectures + 0 practices + 28 seminars = total of 28 hours Course headcount limitations (min.-max.): 5 – 15 Prerequisites: OAK-SE2 completed + OAK-GY2 parallel Topic Introducing the most common and important paediatric surgical conditions in newborns and children. The diagnosis, surgical and nonsurgical treatment and outcomes are discussed. Urological, plastic surgical and traumatological topics will be also included. Conditions for acceptance of the semester Oral exam Mid-term exams Making up for missed classes In justified cases there will be possibility to attend an on call period for substitution. Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Denis Gill, Niall O’Brien: Paediatric Clinical Examination, 2nd edition, Churchill Livingstone 1993 John D. Atwell: Paediatric Surgery, Arnold 1998 Marc I. Rowe: Essential Pediatric Surgery, Mosby 1995 Zacharias Zachariou: Pediatric Surgery Digest, Springer 2009 Peter Vajda, Andrew B. Pinter: Paediatric Surgery, lecture notes for medical students Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 Neonatal surgery I. Oesophageal atresia Abdominal wall defects - gastroschisis / omphalocele Congenital diaphragmatic hernia / relaxation Neonatal surgery II. Duodenal and small bowel obstruction, Meconium ileus, Necrotising enterocolitis, Anorectal malformation General Paediatric Surgery I. Pyloric stenosis Gastrooesophageal reflux Achalasia Median and lateral neck cysts (brachial arch/cleft remnants) General Paediatric Surgery II. Hirschsprung disease Constipation Large bowel polyps Rectal prolapse Anal abscess, fissures, fistulas General Paediatric Surgery III. Inguinal hernia Incarcerated hernia Hydrocele Umbilical hernia Undescended testis Torsion of the testis and ovaries Emergency abdominal surgery in children Appendicitis Intussusception Meckel’s diverticulum Bowel obstruction Benign Tumours in Childhood Dermoid cysts Haemangiomas Lymphangioma Pigmented Nevi Baker’s cyst, ganglions Trigger thumb Paediatric Traumatology/Orthopaedics Blunt abdominal injuries Fractures in childhood Child abuse Paediatric Urology I. Ureterovesical junction obstruction Ureteropelvic junction obstruction Posterior urethral valve Paediatric Urology II. Duplex kidney/ureter (ureterocele, ectopic ureter) Vesicoureteral reflux Cystic kidney diseases Paediatric Urology III. Phimosis, paraphimosis Hypospadias Buried penis Varicocele Miscellaneous: Plastic- and Neurosurgery 405 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 24 25 26 27 28 Cleft lip and palate Myelomeningocele Replacing of missed lectures, consultation Replacing of missed lectures, consultation Oral Exam Oral Exam Exam topics/questions Oesophageal atresia Abdominal wall defects, gastroschisis / omphalocele Congenital diaphragmatic hernia / relaxation Duodenal and small bowel obstructions Meconium ileus Necrotising enterocolitis Anorectal malformation Pyloric stenosis Gastrooesophageal reflux Achalasia Median and lateral neck cysts (brachial arch/cleft remnants) Hirschsprung disease Constipation Large bowel polyps Rectal prolapse Anal abscess, fissures, fistulas Inguinal hernia Incarcerated hernia Hydrocele Umbilical hernia Undescended testis Torsion of the testis and ovaries Appendicitis Intussusception Meckel’s diverticulum Bowel obstruction Dermoid cysts Haemangiomas Lymphangioma Pigmented Nevi Baker’s cyst, ganglions Trigger thumb Blunt abdominal injuries Fractures in childhood Child abuse Ureterovesical junction obstruction Ureteropelvic junction obstruction Posterior urethral valve Duplex kidney/ureter (ureterocele, ectopic ureter) Vesicoureteral reflux Cystic kidney diseases Phimosis, paraphimosis Hypospadias Buried penis Varicocele Cleft lip and palate Myelomeningocele Participants Dr. Farkas András (FAAMAAO.PTE), Dr. Oberritter Zsolt (OBZMAAO.PTE), Dr. Pintér András (PIAMAAO.PTE), Dr. Vajda Péter (VAPFAAO.PTE), Dr. Vástyán Attila (VAAMAAO.PTE) 406 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-IDE NEUROSURGERY DR. TAMÁS DÓCZI, professor Department of Neurosurgery Course director: 3 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 10 Number of hours/semester: 14 lectures + 28 practices + 0 seminars = total of 42 hours Course headcount limitations (min.-max.): 5 – 50 Prerequisites: OAA-AA1 completed + OAA-AA2 completed + OAK-NE1 completed Topic Neurosurgery is a surgical specialty for the treatment of diseases and disorders of the brain, spinal cord, and peripheral and sympathetic nervous system. Most student thinks of neurosurgery as brain surgery; but it is much more! It is the medical specialty concerned with the diagnosis and treatment of patients with injury to, or diseases /disorders of the brain, spinal cord and spinal column, and peripheral nerves within all parts of the body. The specialty of neurosurgical care includes both adult and pediatric patients. Dependent upon the nature of the injury or disease/disorder a neurological surgeon may provide surgical and/or non-surgical care. Thus, this field of medicine can be defined as surgical neurology, as well. Main fields of surgical neurology: neurotraumatology; neurooncology; vascular neurosurgery (cerebrovascular diseases) dealing with subarachnoid haemorrhage, aneurysms, or another vascular malformations; intracerebral haemorrhage and occlusive cerebro-vascular disease. Infectious diseases of the skull, brain and spine: abscesses, infections, postoperative inflammations. Spinal neurosurgery: degenerative diseases of the spinal column, spinal canal stenosis. Diseases of the craniocervical junction (neuroorthopedics). Developmental disorders such as hydrocephalus, spinal dysraphism, etc. Functional neurosurgery treating intractable pain, epilepsy and movement disorders Conditions for acceptance of the semester Attendance of 90 % of lectures/practices Mid-term exams Making up for missed classes Individual replacement is possible. Reading material - Obligatory literature - Literature developed by the Department http://www.cnsc.hu - Notes - Recommended literature Andrew Kaye: Essential Neurosurgery, Blackwell Publishing Lectures 1 2 3 4 5 6 7 8 Symptoms and signs of raised intracranial pressure Dr. Dóczi Tamás Brain tumors Dr. Dóczi Tamás Spinal tumours Dr. Büki András Cranio-cerebral injuries Dr. Büki András Spinal injuries Dr. Schwarcz Attila Cerebrovascular diseases Dr. Dóczi Tamás Functional neurosurgery Dr. Balás István Neurointensive care/Emergency neurosurgery (Dr. Ezer Erzsébet/Dr. Büki András) Dr. Büki András 407 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 9 10 11 12 13 14 Interventional neuroradiology (Dr. Hudák István/Dr. Kövér Ferenc) Dr. Kövér Ferenc Neuroradiology (Dr. Kövér Ferenc/ Prof. Bogner Péter) Dr. Bogner Péter Degenerative diseases of the spine (Dr. Schwarcz Attila/Dr. Kasó Gábor) Dr. Schwarcz Attila Multidisciplanary approaches in neuro-omcology Dr. Horváth Zsolt Developmental/Congenital abnormalities Dr. Vető Ferenc Hydrocephalus Dr. Vető Ferenc Practices 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Case presentation and analysis primarily focusing on the above topics (Symptoms and signs of raised intracranial pressure) Case presentation and analysis primarily focusing on the above topics (Symptoms and signs of raised intracranial pressure) Case presentation and analysis primarily focusing on the above topics (Brain tumors) Case presentation and analysis primarily focusing on the above topics (Brain tumors) Case presentation and analysis primarily focusing on the above topics (Spinal tumours) Case presentation and analysis primarily focusing on the above topics (Spinal tumours) Case presentation and analysis primarily focusing on the above topics (Cranio-cerebral injuries) Case presentation and analysis primarily focusing on the above topics (Cranio-cerebral injuries) Case presentation and analysis primarily focusing on the above topics (Spinal injuries) Case presentation and analysis primarily focusing on the above topics (Spinal injuries) Case presentation and analysis primarily focusing on the above topics (Cerebrovascular diseases) Case presentation and analysis primarily focusing on the above topics (Cerebrovascular diseases) Case presentation and analysis primarily focusing on the above topics (Functional neurosurgery) Case presentation and analysis primarily focusing on the above topics (Functional neurosurgery) Case presentation and analysis primarily focusing on the above topics (Neurointensive care/Emergency neurosurgery) Case presentation and analysis primarily focusing on the above topics (Neurointensive care/Emergency neurosurgery) Case presentation and analysis primarily focusing on the above topics (Interventional neuroradiology) Case presentation and analysis primarily focusing on the above topics (Interventional neuroradiology) Case presentation and analysis primarily focusing on the above topics (Neuroradiology) Case presentation and analysis primarily focusing on the above topics (Neuroradiology) Case presentation and analysis primarily focusing on the above topics (Degenerative diseases of the spine) Case presentation and analysis primarily focusing on the above topics (Degenerative diseases of the spine) Case presentation and analysis primarily focusing on the above topics (Multidisciplinary approaches in neuro-oncology) Case presentation and analysis primarily focusing on the above topics (Multidisciplinary approaches in neuro-oncology) Case presentation and analysis primarily focusing on the above topics (Developmental/Congenital abnormalities) Case presentation and analysis primarily focusing on the above topics (Developmental/Congenital abnormalities) Case presentation and analysis primarily focusing on the above topics (Hydrocephalus) Case presentation and analysis primarily focusing on the above topics (Hydrocephalus) Seminars Exam topics/questions 1. Neurotraumatology; 2. Neurooncology; 3. Vascular neurosurgery: subarachnoid haemorrhage, aneurysms, vascular malformations; 4. Intracerebral haemorrhage; 5. Occlusive cerebro-vascular diseases; 6. Infectious diseases of the skull, brain and spine: abscesses, infections, inflammations; 7. Spinal neurosurgery: degenerative diseases of the spinal column, spinal canal stenosis; 8. Diseases of the craniocervical junction; 9. Developmental disorders: hydrocephalus, spinal dysraphism, etc.; 10. Functional neurosurgery: intractable pain, 11. Epilepsy; 12. Movement disorders 408 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Participants Dr. Balás István (BAIMAAO.PTE), Dr. Dóczi Tamás (DOTHAAO.PTE), Dr. Horváth Zsolt (HOZGABO.PTE), Dr. Kasó Gábor (KAGMAAO.PTE) 409 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-MKF NEUROSURGICAL TREATMENT OF NEUROGENIC PAIN AND MOVEMENT DISORDERS DR. ISTVÁN BALÁS, associate professor Department of Neurosurgery Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 10 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 2 – 20 Prerequisites: OAA-NEA completed + OAK-NE2 parallel Topic Department of Functional Neurosurgery University of Pécs, Hungary is dedicated to the surgical alleviation of movement disorders such as Parkinson’s disease, dystonia, tremor and neuropathic pain syndromes (phantom limb pain, trauma related, failed back surgery syndrome, metabolic, post stroke pain etc.). The service offers deep brain stimulation, spinal cord stimulation, motor cortex-, and peripheral nerve stimulations, or lesional procedures as appropriate. The aim of course to foreshow participants about anatomical, pathological, eletrophysiological basis of extrapyramidal movement disorders (Parkinson’s disease, tremors etc.) and also chronic neurogenic pain. Patient selection, criteria of surgery (indications-contraindications), perioperative investigations, different targeting methods, and surgical procedure, programing of neuropacemakers will be discussed. VIDEO demonstration and analysis of different movement disorders available. According to demand students can participate in surgery. Conditions for acceptance of the semester Maximum 25% missed classes (2 seminars) Mid-term exams Making up for missed classes No possibility to make up for the missed classes. Reading material - Obligatory literature - Literature developed by the Department www.cnsc.hu - Notes Not available. - Recommended literature Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Diagnostics of Parkinson disease Diagnostics of tremors Diagnostics of dystonias Diagnostics of neurophatic pain Preoperative examinations, surgical indications of Parkinson disease Preoperative examinations, surgical indications of tremors Preoperative examinations, surgical indications of disorders Preoperative examinations, surgical indications of neurophatic pain Neuropsychological tests of movement disorders Neuropsychological tests of neurophatic pain Clinical tests of neurophatic pain Clinical tests of movement disorders Surgical technique of movement disorders Electrophysiological tests of movement disorders Exam topics/questions A written form paper is necessary. Participants Dr. Balás István (BAIMAAO.PTE), Dr. Kovács Norbert (KONFAAO.PTE) 410 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-NEG NEUROLOGICAL NEUROGENETICS DIFFERENTIALDIAGNOSIS, RARE NEUROLOGICAL DISEASES, DR. ÁGNES SEBŐK, assistant professor Department of Neurology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 10 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 20 Prerequisites: no prerequisites Topic Through interactive discussion of neurological cases, the diagnosis and differential diagnosis of specific neurological problems will be studied. History, symptoms, and test results will be analysed, based on previous studies in neurophysiology, neuropathology and radiology. Plenty of pictures, videos and some bed-side patient-demonstration will be included. A symptom-oriented approach will be used (e.g. differential diagnosis of ataxias, spasticity), and diagnostic protocols will be discussed. A special attention will be given to rare and genetic diseases. Conditions for acceptance of the semester None Mid-term exams Written exam (miniessay). Making up for missed classes Case study (written). Reading material - Obligatory literature - Literature developed by the Department www.cncs.hu - Notes - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 12 Ataxias 1 Dr. Sebők Ágnes Ataxias 2 Dr. Hadzsiev Kinga Mental retardation 1 Dr. Hadzsiev Kinga Mental retardation 2 Dr. Hadzsiev Kinga Spasticity 1 Dr. Hadzsiev Kinga Spasticity 2 Dr. Sebők Ágnes Epilepsy 1 Dr. Hadzsiev Kinga Epilepsy 2 Dr. Sebők Ágnes Dementia 1 Dr. Sebők Ágnes Dementia 2 Dr. Sebők Ágnes Confusion to coma - neurometabolic diseases 1 Dr. Sebők Ágnes Confusion to coma - neurometabolic diseases 2 Dr. Hadzsiev Kinga 411 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 13 14 Exam and discussion of exam questions 1 Dr. Hadzsiev Kinga Exam and discussion of exam questions 2 Dr. Sebők Ágnes Practices Seminars Exam topics/questions Participants 412 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-NKE CLINICAL CASES: NEPHROLOGY, DIABETOLOGY, HYPERTENSION DR. TIBOR JÓZSEF KOVÁCS, associate professor 2nd Department of Internal Medicine Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 10 Number of hours/semester: 0 lectures + 0 practices + 14 seminars = total of 14 hours Course headcount limitations (min.-max.): 5 – 60 Prerequisites: OAK-NHA parallel Topic The aim of the seminars is to give more information about the various kidney diseases and hypertension through different case presentations. The topic is focusing on clinical, laboratorical, pathological and imaging diagnosis and treatment of most common cases. Conditions for acceptance of the semester The maximum permitted number of absences is 1 seminar (1x2 hours). Mid-term exams Making up for missed classes Reading material - Obligatory literature - Literature developed by the Department - Notes - Recommended literature Harrison’s: Principles of Internal Medicine, 16th edition, McGraw-Hill Medical Publishing Division, 2005. Goldman L., Ausiello D.: Cecil Textbook of Medicine: Single Volume (Cecil Textbook of Medicine), Saunders 2004. I Feehally, J et al: Comprehensive Clinical Nephrology, Mosby 2007 Lectures Practices Seminars 1 2 3 4 5 6 7 8 9 10 11 12 13 14 The indications of renal biopsy and the information given by histological examinations in nephrology. The indications of renal biopsy and the information given by histological examinations in nephrology. Proteinuria. Nephrotic syndrome. Proteinuria. Nephrotic syndrome. Nephritic syndrome. RPGN. Nephritic syndrome. RPGN. Diabetology. Diabetology. Hypertension. Hypertension. Drugs and the kidney. Drugs and the kidney. Cardiovascular diseases - kidneys, diabetes, hypertension. Cardiovascular diseases - kidneys, diabetes, hypertension. Exam topics/questions Exam will be after the last seminar in written form. Participants Dr. Kelényi Gáborné (NAJGAAO.PTE), Dr. Kovács Tibor József (KOTMABO.PTE), Dr. Vas Tibor (VATFACO.PTE), Dr. Wittmann István (WIILAAO.PTE) 413 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-NKT HIGH-RISK PREGNANCY DR. PÉTER TAMÁS, associate professor Department of Obstetrics and Gynaecology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 10 Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours Course headcount limitations (min.-max.): 4 – 40 Prerequisites: OAK-ST1 completed Topic The goal of this course is to give up-to-date information about pathophysiology of high-risk pregnancies, diagnostic pitfalls, and dilemmas of the management. This course has been organized for students who are deeply interested in obstetrics. Conditions for acceptance of the semester Written examination within the last lecture; - Absence of 1-2 hours: acceptable; - Absence of 3-4 hours: requires individual evaluation; the leader of the course may give license for examination; - Absence more than 4 hours: the course is not acceptable, exam is not permitted; Mid-term exams See above Making up for missed classes See above Reading material - Obligatory literature - Literature developed by the Department PowerPoint presentations (by lecturers) - Notes Hand-out of lecturers - Recommended literature Lectures 1 2 3 4 5 6 7 8 9 10 11 Background of habitual abortions, diagnostic and therapeutic opportunities Dr. Csermely Tamás Prenatal screening for chromosomal abnormalities; 3D ultrasound Dr. Vizer Miklós Non-immune hydrops fetalis Dr. Ertl Tibor Pregnancy and cervical carcinoma Dr. Gőcze Péter Intrauterine interventions Dr. Vizer Miklós Three-dimensional ultrasound in obstetrics Dr. Vizer Miklós Early-onset and late-onset preeclampsia Dr. Tamás Péter Hemodynamic and hemorheological alterations in normal and preeclamptic pregnancies Dr. Tamás Péter HELLP-syndrome Dr. Tamás Péter Dilemmas of tocolysis Dr. Tamás Péter Management of preterm premature rupture of membranes Dr. Farkas Bálint 414 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 12 13 14 Causes of intrauterine growth restriction and its diagnostic and therapeutic opportunities Dr. Tamás Péter Fetal hypoxia; diagnosis and management Dr. Farkas Bálint Pregnancy and liver diseases Dr. Tamás Péter Practices Seminars Exam topics/questions - Background of habitual abortions, diagnostic and therapeutic opportunities - Prenatal diagnosis of congenital abnormalities; 3D-ultrasound - Non-immune hydrops foetalis - Pregnancy and cervical carcinoma - Early-onset and late-onset preeclampsia - HELLP-syndrome - Management of preterm premature rupture of membranes - Dilemmas of tocolysis - Causes of intrauterine growth restriction; diagnostic approaches and therapeutic opportunities - Pregnancy and liver diseases - Management of pregnancies following extensive pelvic surgery - Fetal hypoxia; diagnosis and management - The preterm baby Participants Dr. Csermely Tamás (CSTGABO.PTE), Dr. Ertl Tibor (ERTMAAO.PTE), Dr. Farkas Bálint (FABFACO.PTE), Dr. Gőcze Péter (GOPMAAO.PTE), Dr. Tamás Péter (TAPMAAO.PTE), Dr. Vizer Miklós (VIMRAAO.PTE) 415 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-NTR NEUROTRAUMATOLOGY DR. ANDRÁS BÜKI, professor Department of Neurosurgery Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 10 Number of hours/semester: 6 lectures + 6 practices + 2 seminars = total of 14 hours Course headcount limitations (min.-max.): 3 – 25 Prerequisites: OAA-NEA completed + OAP-SPR completed + OAK-NE1 completed Topic Traumatic brain and spinal cord injury is considered the leading cause of death and permanent morbidity in the population under 40. State of the art treatment of such conditions is one of the most cost-efficient medical interventions. This chapter of Neurosurgery deals with acute scenarios physicians should face not only in their practice but also in their everyday „private” life. Completion of the course will enable students to classify various forms of central nervous system injuries while also being capable of decision making in terms of transfer as well as definitive treatment. Conditions for acceptance of the semester Visit at least 75 percent of lectures and practices. Mid-term exams Making up for missed classes Practices could be repeated in a month. Reading material - Obligatory literature - Literature developed by the Department http://cnsc.hu - Notes - Recommended literature http://www.braintrauma.org Gaál Csaba (ed.): Sebészet, 7. átdolgozott, bővített kiadás, Medicina 2010. Lectures 1 2 3 4 5 6 Classification of brain and spinal cord injury Dr. Büki András Advanced Trauma Life Support® in brain and spinal cord injury Dr. Büki András Neuroradiological background of brain and spinal cord injury Dr. Büki András Neurointensive monitoring and care Dr. Büki András Neurosurgical interventions Dr. Büki András Neurorehabilitation in CNS injury Dr. Büki András Practices 1 2 3 4 5 6 Primary survey in head injury Primary survey in spinal cord injury Secondary survey in CNS injury Neuromonitoring in CNS injury Surgical care for CNS injury The practice of neurorehabilitation Seminars 1 2 Classification of CNS injuries Therapeutic algorhythms 416 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Exam topics/questions http://cnsc.hu Participants Dr. Balás István (BAIMAAO.PTE), Dr. Büki András (BUAMAAO.PTE), Dr. Ezer Erzsébet (EZEMAAO.PTE), Dr. Horváth Zsolt (HOZGABO.PTE), Dr. Schwarcz Attila (SCAFABO.PTE), Dr. Vető Ferenc (VEFMAAO.PTE) 417 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 OAE-UEA NEONATAL CARE IN THE DELIVERY ROOM (ADAPTATION) DR. TIBOR ERTL, professor Department of Obstetrics and Gynaecology Course director: 1 credit ▪ midsemester grade ▪ Elective module ▪ spring semester ▪ recommended semester: 10 Number of hours/semester: 6 lectures + 6 practices + 0 seminars = total of 12 hours Course headcount limitations (min.-max.): 5 – 25 Prerequisites: OAK-GT3 completed + OAP-PA2 completed Topic As a result of establishing Perinatal Intensive Care Centers, the possibility of studying physiological changes in the perinatal period became a reality within one institute. The investigation of neonatal adaptation has been an important scientific field at our department for decades. We detected basic physiologic and pathophysiologic changes with regard to the prevention of respiratory distress and hormonal influence on renal function. We investigated the effect of delivery mode on the transition from fetus to newborn. This practiceoriented course provides the possibility of studying delivery room management as well as the complications of prematurity on the shortterm adaptation and long-term consequences. Conditions for acceptance of the semester Maximum of absence 25% (=3 hours) Mid-term exams Making up for missed classes There is no possibility to make up for the missed classes. Reading material - Obligatory literature - Literature developed by the Department - Notes Notes in the lectures and practicals. - Recommended literature John P. Cloherty (ed.): Manual of Neonatal Care, 2008 www.neonatology.com Lectures 1 2 3 4 5 6 Hormonal changes during delivery Dr. Ertl Tibor Neonatal adaptation Dr. Ertl Tibor Adaptation problems of preterm infants Dr. Ertl Tibor Chronic diseases of preterm infants Dr. Ertl Tibor Metabolic adaptation disorders in preterm infants Dr. Ertl Tibor Perinatal infections Dr. Ertl Tibor Practices 1 2 3 4 5 6 Neonatal assessment in the delivery room Transport of preterm infants Monitoring sick newborns Methods of breathing support in newborns Screening and treatment of complications of prematurity Habilitation of sick newborns 418 UP MS General Medicine major – Elective and Optional Subjects - Course descriptions – academic year of 2015/2016 Seminars Exam topics/questions Participants Dr. Ertl Tibor (ERTMAAO.PTE) 419