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Advanced Placement Biology Syllabus Philosophy AP Biology is one of the upper-level science courses taught at our school. Teaching AP Biology gives me an opportunity to facilitate lessons in which our students learn science as a process. Many students will enroll in this course and other science courses because they enjoy learning about science. Students will gain a rich conceptual understanding of content as they develop questions, form hypotheses, and design experiments to provide evidence of fundamental biological concepts. First, and foremost, our key responsibility is to help our students develop a love of science based on knowledge and exploration. Instructional Objective The AP Biology Course provides an opportunity for high school students to pursue and receive credit for college level course work completed in secondary high school classes. The AP Biology course is based on the premise that college-level material can be taught successfully to enthusiastic, academically able secondary school students. In essence, the AP Program is a cooperative endeavor that helps high school student’s complete college-level courses and permits colleges to acknowledge and encourage this endeavor through the granting of appropriate credit and placement. The College Board Curriculum Framework provides guidance in allocating the time spent during the year in teaching units on Evolution, Ecology, Genetics, and Information transfer through organisms and populations. The curriculum is focused on four Big Ideas that guide students in exposure to the interrelationship of biological concepts. Twenty-five percent of total instructional time should reflect student participation in laboratory investigations. A more student-directed, inquiry-based lab experience supports the AP Biology course revision and AP Course Audit Curricular Requirements as it provides opportunities for students to design plans for experiments, data collection, application of mathematical routines, and to then refine testable explanations and predictions. Laboratory investigations support the recommendation by the National Science Foundation that “science teachers build into their curriculum, opportunities for students to develop skills in communication, teamwork, critical thinking, and commitment to lifelong learning.” Textbook Correlation Biology, 11th edition Authors: Sylvia Mader and Michael Windelspect Copyright 2013 McGraw-Hill publishers Curricular Content Requirements The Big Idea focus will be visually displayed in classroom posters, computer image projection, and on bulletin board student assignment documents. • Big Idea 1 - The process of evolution drives the diversity and unity of life. • • • Big Idea 2 - Biological systems utilize energy and molecular building blocks to grow, reproduce, and maintain homeostasis. Big Idea 3 - Living systems retrieve, transmit, and respond to information essential to life processes. Big Idea 4 - Biological systems interact, and these interactions possess complex properties. For each of the four Big Ideas, there is a set of Enduring Understandings which incorporates core concepts that students should retain from these learning experiences. AP Biology Laboratory Investigations and Science Process Skills Students will complete at least two of the recommended AP Biology lab investigations for each Big Idea. These core labs are supplemented with additional labs to enhance students’ understanding of major concepts. Students will be engaged in hands-on laboratory investigations for more than 25% of classroom instructional time. Student-directed labs will be accompanied by written lab reports that include: a primary question, reference to a Big Idea, experimental outline and variables, procedural steps necessary for investigation, appropriate charts, graphs and data tables, and finally an analysis of results that leads to formulation of a valid conclusion for the investigation. Appropriate mathematical routines will be implemented during investigations to summarize and validate experimental data and results. Class lessons will be planned with an emphasis on implementation of Scientific Inquiry as students make observations, pose questions, examine books and other sources of information to see what is already known and ultimately communicate results of investigations. Students will develop scientific skills that allow them to make predictions, use critical and logical thinking, and consider alternative explanations of results. Inquiry teaching methods will increase student understanding of how scientists study the natural world. A variety of lab skills are necessary for successful implementation of investigations. The Science Practices enable students to establish lines of evidence and use them to develop and refine testable explanations and predictions of natural phenomena. Science practices will be incorporated throughout the entire year during classroom lab investigations, written lab reports, and independent student research projects. 1.0 The student can use representations and models to communicate scientific phenomena and solve scientific problems. 2.0 The student can use mathematics appropriately 3.0 The student can engage in scientific questioning to extend thinking or to guide investigations within the context of the AP course. 4.0 Student can plan and implement data collection strategies in relation to a particular scientific question. 5.0 The student can perform data analysis and evaluation of evidence. 6.0 The student can work with scientific explanations and theories. 7.0 The student can connect and relate knowledge across various scales, concepts, and representations in and across domains. Course Overview AP Biology is taught as a second high school biology course, so I work closely with the Pre-AP Biology and Chemistry teachers to correlate activities and lessons. Some of our students enroll as sophomores and take chemistry and AP Biology concurrently, while most take the course in the twelfth grade. Class sessions presently occur on a 90 minute block schedule, however we may return to the 50 minute daily class schedule in the future. Students also spend an additional two hours per week in after-school tutorials. Four Saturday district-run Prep sessions are provided including one dedicated to labs only. Because we also work closely with other district schools to coordinate lesson plans, lecture notes, AP practice tests (two per six weeks), after school and Saturday tutorials, and labs activities, along with our tutoring schedules, students are encouraged to attend tutorials offered by the other schools in the district to aid in understanding. Finally, students are expected to maintain a lab notebook for all the required AP labs and sign a contract to take the AP exam in May. Student notebook documentation of assignments is used for review before the AP Exam in May. Big Idea Enduring Understanding Big Idea 1 Course outline/timeline AP Biology labs /activities Unit 1 –Introduction to Evolution (10 days) Chapter 1 The process of evolution drives the diversity and unity of life. • • 1C Changing environment Scientific methods are used for investigations. Biologists make observations and formulate hypotheses. Chapter 22 • • • Inferences and observations Darwin made on the Galapagos Islands. Natural selection and adaptation create evolution. DNA and fossil record provide evidence for evolution. Lab: Scientific Methods Activity – Is it Alive: Sewer Lice Observation Lab: Origins of Life Video: Journey of Man Video: Evolution Change and Common threads Chapter 24 1D Natural processes • • • Biological species emerge from reproductive isolation. New species originate from sympatric and allopatric speciation. Punctuated equilibrium shows the tempo of evolution. Macroevolution illustrates evolution. Chapter 25 1B Common ancestry • • • • Phylogeny has a biogeographic basis The history of life is punctuated by mass extinctions. Phylogenetic trees are hypotheses. Three domains of life on earth. Student project: Create a model geographical timeline AP Lab – Artificial Selection HHMI lab – Battling Beetles to illustrate species interaction Big Idea 2 Unit 2 – Molecules and Cells (15 days) Chapter 3 Biological systems utilize energy and molecular building blocks to grow, reproduce, and maintain homeostasis. • 2A Properties of water • Illustrate how the structure of water determines its function. Student project: Survey of water pH and temperature on the diversity of life of local ponds. Article: The harm done by Acid Deposition Lab: Diversity and Environmental factors Chapter 4 • Big Idea 4 Correlation 4A –Nucleic acids and protein. 2B Internal Compartments Movement across membranes 2E Growth, reproduction Big Idea 4 Correlation 4A Membrane bound structures. Kidney- matter movement. 2D Dynamic homeostasis Big Idea 3 Correlation Cells communicate Carbon chemistry provides building blocks of organic molecules Chapter 5 • • Characteristics of lipids, proteins, carbohydrates, and nucleic acids Discussion – Protein shape changes if hydrogen bonds disrupted. Chapter 7 – required content • • Discuss /create models of organic compounds. Activity: Slide show of ultra structures of the Eukaryotic cells Compare prokaryote and eukaryote cells. The endomembrane system, cell surfaces, and junctions. Chapter 8 • • • • • • • • Membranes are mosaics of structure and function A membranes molecular organization results from selective permeability Student research – Receptor proteins are vital for immune responses. Water flow is facilitated by aquaporins. Student research project: nerophrogenic diabetes insipidus caused by non-functional aquaporins. (Chapter 44 – related content) Comparison of homeostasis and regulation of body temperature. Compare/contract osmoregulation and lower animal excretory systems. Homeostatic mechanisms reflect common ancestry and adaptation in different environments. Model: construct a model of a cell membrane or proton pump AP Lab: Diffusion Osmosis lab Model construction: The sodium/potassium pump Discussion – cell walls of bacteria, protists, fungi and plants. Article: One Bad transporter and cystic fibrosis Article: Truth in a test tube: Using urine to test for bodily functions. Chapter 11 • • • Cell signaling evolved early in the evolution of life. Receptions, transduction and response to signals Signal receptors are plasma membrane proteins Model – Illustrate the activation of a gene by a growth factor. 2A Free energy 2C Biological Feedback systems mechanisms utilize energy and Big Idea 4 molecular Correlations building 4B – coenzymes blocks to and cofactors grow, affect enzyme reproduce, function and Big Idea 4 maintain Correlations homeostasis. 4B-Interactions promote efficiency 2A Big Idea 2 Living systems require free Biological energy and systems matter utilize energy and molecular building blocks to grow, reproduce, and maintain homeostasis Big Idea 2 Unit 3 – Energy Transformations (4 days) Chapter 6 – required content • • • • • • • • Discussion of Law Of Thermodynamics Vitamins are essential to cellular metabolism. Enzymes speed up metabolic processes Activity: Cause of disease- rickets, pellagra, scurvy Discussion: minerals and osteoporosis Metabolic control often depends on allosteric regulation. (Chapter 41 – related content) Digestive enzymes facilitate nutrient acquisition in cells throughout the body. Nutrients are necessary for homeostasis. Unit 4 – Energy and Environmental Interaction (10 days) Chapter 9 – required content • • Cellular respiration and fermentation are catabolic, energy-yielding processes. Respiration involves glycolysis, the Krebs cycle, and the electron transport chain. Chapter 10 – required content • • • Autotrophs use chloroplasts to initiate photosynthesis. The products of the light reactions are used to assemble carbon compounds during the Calvin cycle. Photosynthesis is the biospheres metabolic foundation. Chapter 36 • • • • • Selective permeability, proton pumps, and water potential drive water transport in plants. Aquaporins increase the rate of water transport. Symplasts and apoplasts function in plant tissue. Transport of xylem sap and translocation of phloem sap distribute water in plants. Xerophytes have evolutionary adaptations that reduce transpiration. Lab - Toothpickase data and calculation of reaction rates Article: A toast to Alcohol Dehydrogenase Article: Hormones and Hunger AP Lab –Cellular Respiration Article: When mitochondria Spin their wheels Lab - Fish respiration lab AP Lab – Photosynthesis Article: Biofuels Independence In Nature –the role of respiration and photosynthesis in global warming AP Lab - Transpiration Big Idea 4 Biological systems interact, and these interactions possess complex properties. 4A Interactions in systems Big Idea 1 Correlations 1A Genetic makeup of a population Big Idea 3 Correlations 3EOrganisms exchange information 4C Interactions with the environment Unit 5 – Ecosystems Interactions (12 days) Chapters 50 • • • Interactions between organisms and their environment determine the distribution and abundance of organisms. Abiotic factors affect species dispersal, distribution and habitat Geographic distribution of aquatic and terrestrial biomes Chapter 37 • • • Legume root examination, nitrogen as a plant nutrient. Nutritional adaptations: symbiosis of roots and microbes Parasitism and predation adaptations in plants. Chapter 51 • • • Ethology explores both the proximal and ultimate cause of behavior in organisms. Behavioral ecology emphasizes evolutionary hypotheses. Organism acquire learning, cognition, and social behaviors Chapter 54 • • • Lab – Owl Pellet dissection Predator/prey relationships AP Lab – Energy Dynamics Research: Hydroponics growth of plants for human consumption Activity - Behavior of planarians Article: My Pheromones Made me do it! Research: Climate changes in Texas Tropic relationships determine the routes of energy flow and chemical cycling in ecosystems Analyze the nitrogen, phosphorus, water, and carbon cycles Human activities may cause climate change. Chapter 39 • • • Plant responses to hormones, light and environmental stimuli. Plant defense to herbivores and pathogens Activity: Seed germination vs. light Lab – Plant tropisms Unit 6– Genetics, Reproduction and Development (20 days) Chapter 12 Big Idea 3 Living systems retrieve, transmit, and respond to information essential to life processes. 3A Heritable Information 3B Cellular and molecular mechanisms • • Mitosis and control of the Cell Cycle Cancer cells have escaped cell cycle control AP lab: Cell Division: Mitosis and Meiosis Chapter 13 • • • • • Meiosis and origins of Genetic Variations Sexual life cycles produce genetic variation among organisms Asexual reproduction is an advantage for some organisms (Chapter 46 & 47 – related content) A complex interplay of hormones regulates reproduction Embryonic and fetal development occur during preganancy Chapter 45 • • • The endocrine and nervous systems are structurally, chemically, and functionally related The hypothalamus and pituitary integrate many functions Thyroid hormones function in development, bioenergetics and homeostasis. Chapter 38 – Reproduction in flowers • • • 3C Processing genetic information is imperfect Male and female gametophytes develop within anthers and ovaries. Seeds containing embryos develop from ovaries when provided with a supply of nutrients. Evolutionary adaptations of seed germination contribute to seedling survival Sexual and asexual reproduction are complimentary in the life histories of plants Chapter 14 • • Gregor Mendel, Punnett squares, dihybrid crosses, and genetic problems reveal inheritance patterns Article: Blue people characteristics Chapter 15 • • Morgan traced a gene to a specific chromosome Independent assortment of chromosomes and crossing over produce genetic recombination Chapter 48 3D Cells communicate Chemical signals • • Nervous systems perform three overlapping functions of sensory input, integration, and motor output Analyze the evolution and diversity of nervous systems Chapter 43 • • • • Nonspecific defense mechanisms fight infection Lymphocytes provide the specificity and diversity of the immune system. T cells and B cells orchestrate immune responses to pathogens Trace the history and pathology of the AIDS, an immunodeficiency disease caused by a virus. Lab – Flower dissection Article – Plight of the Honeybees Activity: Pedigree analysis Activity – Genetics Corn and Chi Square Activity – M & M Chi square Activity – Karyotype analysis Discussion: Tay-Sachs disease malfunction of lysosomes. Lysosomes facilitate apoptosis; programmed cell death – cellular differentiation Model: Neuron stimulation Activity: Stages of Immune response Video: AIDS – Evolution of an Epidemic Big Idea 3 Living systems retrieve, transmit, and respond to information essential to life processes. 3A Heritable Information 3B Expression Molecular mechanisms Big Idea 4 Correlation 4C Diversity among components of the environment Unit 7 – Molecular Biology (15 days) Chapter 16 • • Rosalind Franklin, Watson, and Crick formulated a model for the DNA double helix. A large team of enzymes are used for correct connection of nucleotides during DNA replication. Chapter 17 • • • The study of metabolic defects provides evidence that genes specify proteins. Transcription is DNA-directed synthesis of RNA Translation is RNA-directed synthesis of a polypeptide Video: DNA: The Secret of Life Activity- DNA extraction from both plant and animal specimens Model: DNA replication Video: The Double Life of RNA Chapter 18 – Virus & Bacteria • • • • • • Viruses can only reproduce in a host cell Phages reproduce during the lytic and lysogenic cycle The short generation span of bacteria helps them adapt to changing environments. Control of gene expression enables individual bacteria to adjust their metabolism to environmental change Control of gene expression, operons, enables individual bacteria to adjust metabolism to their environment. Research Project – Effect of Intestinal E. coli on human digestion. AP Lab – Transformation Research: Embryonic Stem cells Chapter 19 • 3E Transmission of information Results in changes • Repetitive DNA and other non-coding sequences account for much of the eukaryotic genome Oncogene proteins and faulty tumor-suppressor proteins interfere with normal signaling pathways. Video: Ghost in your Genes Epigenome inheritance Chapter 20 • • • Restriction enzymes are used to make recombinant DNA. RFLP analysis detects DNA differences. PCR clones DNA. DNA technology offers forensic, environmental and agricultural applications. Student Research – Xenotransplantation : animal organ transplants Chapter 21 • • • Embryonic development involves cell division, cell differentiation, and morphogenesis A cascade of gen activations sets up the segmentation pattern in Drosophilia. Homeobox genes direct the identity of body parts. AP Lab – Restriction Analysis Article: Golden Rice or Frankenfood? Unit 8– Evolution of Populations (8 days) Big Idea 1 AP Lab – Hardy Weinburg The process of evolution drives the diversity and unity of life. Chapter 23 1B Common ancestry • • • • A populations pool is defined by the allele frequency Hardy-Weinberg theorem describes a non-evolving population Macroevolution is caused by genetic drift and natural selection Adaptive evolution: selectioncan be directional, diversifying, or stabilizing. 1C Chapter 25 Changing • Paleontologist use the fossil record to reveal the evolution of life as punctuated by mass extinctions. environment • • Phylogenetic systematics is based on cladistic analysis Activity - Cladogram Analysis Chapter 26 1D Natural processes Big Idea 4 Biological systems interact, and these interactions possess complex properties. 4B Competition and cooperation 4C Diversity Interactions in the environment • • • Life on earth originated close to 3.5 billion years ago. Animal diversity exploded during the early Cambrium period Plants, fungi and animals colonized the land about 500 million years ago. Unit 9 – Environmental Interrelationships (8 days) Chapter 52 • • • Exponential growth and limits of carrying capacity Identify population-limiting factors Age Structure Diagrams Chapter 53 • • • • Competitive exclusion hypothesis Characterize predation: mimicry and co-evolution Terrestrial and aquatic ecosystem structure Evaluate food webs and successions Chapter 55 • • Genetic, species, and ecosystem diversity are vital to human welfare. Habitat destruction, introduced species, overexploitation, and food chain disruption threaten biodiversity. AP Lab – BLAST Field trip: Fossil Rim wildlife center and Dinosaur National Park – Glen Rose, Texas Student project: Document evidence for changes in the life history of Texas over millions years. Activity - Yeast population study Web/CD 53A:Madagascar and the Biodiversity Crisis WebCD55B: Introduced Species: Fire Ants\ Unit 10 – Special Topics Student long term independent projects: 3A • 4A • 4B • • Create portfolios of diseases with genetic engineered cures. Find example of an invasive species and document the environmental impact of unlimited predation on native species. Research a famous behaviorist and illustrate the scientific concepts we have learned about interrelationships among organisms. Research the transmission of malaria and effect on associated populations. Survey demographic data to illustrate the number of sickle cell anemia victims.