Health Care

S. No.
Products /Processes Under Development Through BIPP Support
Company/Collaborator(s)
Product/Process Description
Name
Health Care
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
Drugs/Therapeutics
ARA Healthcare Limited, Anti- TNF-alpha Antibody scFv for treatment of
Gurgaon
Inflammatory Diseases
TCG Life Sciences Limited, Process
for
Asymmetric
Synthesis
of
Kolkata
Hexahydrobenzophenanthrenes, Dopamine D1 Agonists
Technology development for implant based sustained
Bharat Serums and Vaccines
release formulations incorporating therapeutic peptides/
Limited, Mumbai
recombinant proteins
(i) Amrita Therapeutics
Limited, Ahmedabad
(ii) National Institute of
Identification and Development of Promiscuous Anticancer
Immunology, New Delhi
Compounds from Microorganisms
(iii) B.V. Patel PERD Centre,
Ahmedabad
Life Care Innovations Pvt. Production of poly (lactide-co-glycolide) nanoparticles
Ltd., Gurgaon
(PLG-NP )and poly (lactide-co-glycolide) nanoparticles
encapsulating antitubercular drugs (rifampicin, isoniazid and
pyrazinamide- PLG-NP-ATDs) in GMP facilities
Incozen Therapeutics Pvt. Discovery and Development of potent, selective and novel
Ltd., Hyderabad
c-Met kinase inhibitors in cancer
(i) Sphaera, Manesar
(ii) Leadinvent, Delhi
(iii) International Centre for
Novel combination therapy for treatment of resistant and
Genetic Engineering and
non responsive cancers
Biotechnology , New
Delhi
Rasayani Biologics Pvt. Ltd., Evaluation of Platinum Nano Particles for the Treatment of
Pune
Hormone Refractory Prostate Cancer
Panacea Biotec Ltd., New
Development of novel peptide based topical gel for the
Delhi
treatment of alopecia
(i) Anthem Biosciences Pvt. Ketoreductases - Whole Cell Biotransformation for chiral
Ltd., Bangalore
chemistry
(ii) Cellworks Research India
Pvt Ltd., Bangalore
(i) Mitra Biotech Pvt. Ltd., Development of PAT-1102, a novel HDAC inhibitor for the
Bangalore
treatment of cancer
(ii) Anthem Biosciences Pvt.
Ltd., Bangalore
Crystalin Research Pvt. Ltd., Pre-Clinical studies of novel anticancer drug cocrystal
Hyderabad
Vitas Pharma Research Pvt. Novel inhibitors of fatty acid biosynthesis for the treatment of
Ltd., Hyderabad
drug resistant S.aureus bacterial infections
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
Orchid
Chemicals
&
Pharmaceuticals
Ltd.,
Shozhanganallur
Phyto Biotech Pvt Ltd.,
Kolkata
Natural Remedies Private
limited, Bangalore
Scale up and validation of technology for the manufacture of
DAG using Deacetylcephalosporin C synthase
Novel Technology for Microbial Production of Paclitaxel, an
anticancer drug
Scale-up facilities for the production of phytochemical
reference substances from Indian medicinal plants of national
relevance as a business model
Excel Matrix Biological Novel Haemostasis Mechanisms
Devices Pvt. Ltd., Hyderabad
Yasham P2D Lifesciences Tumor necrosis factor - alpha (TNFa) inhibiting compound
Pvt. Ltd., Mumbai
as a first in class drug treatment for neuroinflammatory
diseases
(i) Enem Nostrum Remedies Discovery and Development of Novel Bone anabolic agents
Pvt. Ltd., Mumbai
for accelerated fracture healing
(ii) CDRI, Lucknow
Symmetrix
Biotech, Development of Anti Thrombin-clot specific streptokinase
Chandigarh
(ACSSK), A Novel Thrombolytic with twin properties of clot
dissolution and prevention of arterial re-occlusion during the
treatment of Acute myocardial infarctio and Ischemic Stroke
Usha
Biotech
Ltd., Rapid Production of Proteins Using CELL EXPRESS - 100 (a
Hyderabad
novel mammalian expression system
PNB Vesper Life Science CLINICAL
DEVELOPMENT
OF
NOVEL
CCK
PVT LTD, cochin, Kerala
RECEPTOR ANTAGONISTS FOR THE TREATMENT OF
INFLAMMATORY PAIN
Bugworks Research India Novel antibiotics for Gram negative bacteria: Structure based
Pvt. Ltd., Bangalore
strategy to Ameliorate antibiotic efflux and enhance
compound efficacy
(i) Unichem Labs Ltd.,
An integrated approach to develop recombinant selerotium
Bardej
rolfsii (SRL) antitumor tectins I E.coli as novel targeted
(ii) Karnatak University,
anticancer drug and drug delivery system for human colon and
Dharwad
breast cancer, providing affordaable health care to cancer
patients
Vaccines
Virchow Biotech Private
Development Of A Novel Mucosal Vaccine For Hpv
Ltd., Hyderabad
Gennova Biopharmaceuticals Development of a cost effective prophylactic and
Limited, Pune
Therapeutic Recombinant Human Papillomavirus vaccine
(i) Serum Institute of India
Limited, Pune
(ii) Indian Institute of
Design and evaluation of novel immunogens and
Science, Bangalore
monoclonal antibodies against pandemic H1N1
(iii) National Institute of
Immunology, New Delhi
Tergene Biotech Pvt. Ltd.,
Development of an Affordable, Asia specific 15 valent
Secunderabad
Pneumococcal Ploysaccharide - CRM 197 protein conjugate
Vaccine
29.
Tergene Biotech Pvt. Ltd.,
Secunderabad – Phase 2
30.
Panacea Biotec Ltd., New
Delhi
31.
32.
33.
34.
35.
36.
37.
38.
Development of an Affordable, Asia specific 15 valent
Pneumococcal Polysaccharide - CRM 197 Protein Conjugate
Vaccine
Development of safe and highly efficacious 13-valent
pneumococcal conjugate vaccine against Streptococcus
pneumoniae infections
Serum Institute of India Ltd.,
Development of HPV Vaccine
Pune
Diagnostics/Devices/Implants
Bigtec Private Limited, Point-of-Care detection of infectious disease using handheld
Bangalore
microPCR
Amar
Immunodiagnostics
Immunodiagnostic kits for detection of autoimmune diseases
Pvt. Ltd., Hyderabad
Chromous Biotech Pvt. Ltd., Multiplex Fast-PCR based diagnosis and prognosis of
Bangalore
tuberclulosis
(i) C-CAMP, Bangalore
(ii) Indian
Institute
of
Flow analyzer
Technology, Madras
Transasia Biomedical Ltd., To develop novel 3rd Generation HIV (Antibody) & 4th
Mumbai
generation (HIV Antigen and Antibody) immunoassay
forma using flash type chemiluminiscence and magnetic
particles as matrix
(i) Design Innova, New
Delhi
(ii) International Centre for Design and development of an affordable fluorescence reader
Genetic Engineering and for point-of-care diagnostics
Biotechnology,
New
Delhi
(i) Janacare Solutions Pvt.
Ltd., New Delhi
(ii) All India Institute of
Medical Sciences, New
Delhi
DXPhone
(iii)Narayana
Hrudayalaya
Hospital City, Bangalore
39.
Optra Systems Pvt. Ltd., Pune ONCOSCAN – Digital Oncopathology slide Scanner
40.
Perfint Healthcare Pvt. Ltd.,
Chennai
Strand
Life
Science,
Bangalore
Frontier Lifeline Private
Limited, Chennai
(i) Vinvish Technologies Pvt.
Ltd., Trivendrum
(ii) Centre for Earth Sciences,
Trivandrum
41.
42.
43.
Solution for planning, execution and confirmation of
targeted ablation therapy
Hepatotoxicity prediction platform
Porcine Pulmonary Xenograft
Cardiovascular Surgery
as
a
Conduit
in
Design and Development of photo dynamic therapy laser
system
(iii)Regional Cancer Centre,
Thiruvananthapuram
44.
45.
46.
47.
Agada
Medical
Technologies, Chennai
Merkel Haptic Systems Pvt.
Ltd., Chennai
Panacea
Medical
Technologies Pvt. Ltd.,
Bangalore
Achira Labs Pvt. Ltd.,
Bangalore
Hi-fidelity affordable mannequin for effective CPR
(Cardiopulmonary Resuscitation) Training
Development of Flat Panel Computed Tomography (FPCT)
machine
Electrophoretic pre-concentration to enable the fluorescencebased detection of ultra-low concentrations of analytes in
human sera at the point-of-care
(i)
48.
49.
50.
51.
Axxonet
System
Technologies,
Bangalore
(ii)
NIMHANS, Bangalore
Sahajanand
Medical
Technologies Pvt. Ltd., Surat
Tuscano Equipments Private
Limited, Chennai
(i)
DSS Imagetech Pvt.
Ltd., New Delhi
(ii)
Dr. B. R. Ambedkar
Center for Biomedical
Research
(ACBR),
New Delhi
Percutaneous Aortic Valve Technology
Automated Portable Epilepsy-EEG system
Development & building indigenous capability for Balloon
Catheter Manufacturing
Imaging device for monitoring breast tissue changes
(iii)
Validation, Field Trial, Scale-up and Commercialisation
of Sensitive and Specific PCR based Diagnostic kit and
Instruments for diagnosis of Chlamydia and Nisseria
infection
Clinical Trials
52.
53.
54.
55.
(i) Bharat Biotech
International Limited,
Hyderabad
(ii) Christian Medical
College, Vellore
(iii)KEM Hospital Research
Centre, Pune
(iv) Translational Health
Science and Technology
Institute, New Delhi
Torrent
Pharmaceuticals
Limited, Gandhinagar
Phase III Testing and Evaluation of Safety and Efficacy of
Oral Rotavirus Vaccine Candidate 116E
A strategy for the Development of Alternative treatment for
Heart failure complicated with diabetes mellitus
Clinical development of TRC150094, a novel
Torrent
Pharmaceuticals Diiodothyronine (T2) analogue, for the treatment of
Limited, Gandhinagar
cardiovascular (CV) risk factors defined by Metabolic
Syndrome (MS).
Safety and efficacy of TRC 150094 in treatment of cardioTorrent
Pharmaceuticals
metabolic risk inoverweight/obese diabetic and pre-diabetic
Limited, Gandhinagar
subjects with dyslipidemia - Phase II trials
56.
57.
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72.
Biocon Limited, Bangalore
Panacea Biotec Limited,
New Delhi
V-Life Sciences Technology
Pvt. Ltd., Pune
A Multicenter, Randomized, Double-Blind, Placebo Control
Study of IN-105 tablets [oral insulin] in Patients with Type 2
Diabetes Mellitus who have inadequate Glycemic Control
on Optimal doses of Extended Release Metformin Tablets.
Development of a H1N1 pandemic influenza vaccine
Clinical Investigation of Galnobax for the treatment of
Diabetic foot Ulcers
To determine the safety, effective dose and frequency of
V-Life Sciences Technology application of Galnobax TM in 50 subjects during Phase I
Pvt. Ltd., Pune
trial in the subjects suffering from diabetic foot ulcers –
Phase 2
A Multicentric, Parallel Randomised (2:1) Open Label
Phase III Clinical Study To Evaluate The Immunogenicity
Biological
E
Limited., And Safety Of BE’s Inactivated JE Vaccine In Healthy ≥1
To <3 Year Old Indian Subjects In Comparison With
Hyderabad
Purified Inactivated JE Vaccine (IXIARO®) Of Intercell –
An Non-Inferiority Study
Cadila Pharmaceuticals Ltd., Clinical Development of Influenza Vaccines
Ahmedabad
Biogenerics/Biosimilars
Sun
Pharmaceutical Bevaciumab upto Pre-clinical studies
Industries Ltd., Vadodra
Gennova Biopharmaceuticals
Bio-similar interferon beta 1a: process development
Limited, Pune
Clonz Biotech Pvt. Ltd., Production of ranibizumab a recombinant humanized AntiHyderabad
VEGF monoclonal antibody fragment (recombinant huFab
V2) expressed in Hansenula Ploymorpha`
Navya Biologicals Pvt. Ltd., Development of novel intensified technology platform for
Hubli, Karnataka
production of low cost Mabs
Development of animal component free biosimilar
Wockhardt
Limited,
recombinant protein therapeutics using mammalian platform
Aurangabad
technology
Serum Institute of India
Clinical Development of Polysialylated Erythropoietin
Limited, Pune
IMGENEX India Pvt. LTd., Development of High Expression plasmid vectors for
Bhubaneswar
production of biosimilar herceptin and other recombinant
proteins and antibodies
IMGENEX India Pvt. LTd., Bio-process development for production of Biosimilar
BhubaneswarTrastuzumab – Second Phase
Intas
Biopharmaceuticals Mucosal formulations of Parathyroid hormone (PTH)
Pvt. Ltd., Ahemedabad
Vivo Biotech Ltd., Hakimpet, Optimization of Scale-up/Purification and clinical grade
Andhra Pradesh
material generation of recombinant Urate Oxidase
Inbiopro Solutions Pvt. Ltd., Interferon Beta 1b process development
Bangalore
73.
74.
75.
76.
(i) Bhat Biotech (I) Pvt. Ltd., Design and expression of humanied antibodies against soluble
Bangalore
Interleukin-6^ soluble gp130 in Bacterial and Animal Cell
(ii) Manipal Life Sciences lines
Centre, Manipal
Apcegen
Kanpur
Technologies, Generation Of Proof Of Concept For Animal Studies of PEG
Conjugated Fully Human Fab’ Antibody Fragment Expressed
in E. Coli For the Treatment of Rheumatoid Arthritis
Stemcells
Stempeutics Research Pvt. A parallel group randomized open blinded end point
Ltd., Bangalore
evaluation, multicentric, dose escalation, phase –II study
assessing the safety and efficacy of intra-arterial (hepatic)
ex-vivo cultured adult allogenicmesenchymal stem cells in
patients with alcoholic liver cirrhosis
Ravindranath GE Medical Functional evaluation of autologous cell based therapy in
Associates
Pvt.
Ltd., cardiovascular diseases - Molecular imaging (An innovative
Hyderabad
non-invasiv technology"
Agriculture
Transgenics
77.
78.
Maharashtra Hybrid Seeds
Company Limited, Jalna
Maharashtra Hybrid Seeds
Company Limited, Jalna
79.
Metahelix Life Sciences
Private Limited, Bangalore
80.
Metahelix Life Sciences
Private Limited, Bangalore
81.
(i) Bioseed Research India
Ltd., Hyderabad
(ii) International Centre for
Genetic Engineering and
Biotechnology , New
Delhi
82.
83.
84.
JK Agri Genetics Ltd.,
Hyderabad
(i) Mother Dairy Fruit and
Vegetable Private
Limited, Noida
(ii) University of Delhi, South
Campus, New Delhi
(i) Bejo Sheetal Seeds
Private Limited, Jalna
(ii) International Centre for
Genetic Engineering and
Stress tolerant rice
Development of Sucking Insect Pest tolerant rice and cotton
A proposal for funding of deregulation trials of transgenic
rice events expressing Metahelix synthetic Cry1C, Cry1Ac
and Cry1Ab genes for tolerance to rice yellow stem borer,
Scirpophaga incertulas
Deregul action trials phase I of transgenic maize events
expressing Metahelix Synthetic Cry1C, Cry1Ac and Cry1Ab
Genes for tolerance to stem and cob borers
Development of rice hybrids with improved drought and
salinity stress tolerance
Development of Bt-rice with two cry genes
To conduct confined field trials and biosafety studies on
genetically engineered Brassica juncea (Male sterility and
restorer lines as pollination control mechanism) for heterosis
breeding and yield improvement
Development of ‘Herbicide & Stress tolerant’ transgenic
Onion
85.
86.
87.
88.
89.
90.
91.
92.
93.
94.
95.
Biotechnology , New
Delhi
(i) GEO
Biotechnologies Association mapping and whole genome marker assisted
India
Pvt.
Ltd., recurrent selection for development of abiotic stress resilient
Bangalore
Maize
(ii) CIMMYT, Hyderabad
Marker Assisted Selection
Advanta India
Secunderabad
Limited,
Multistacking genes to develop engineered rice with
enhanced drought and multiple disease and pest resistance
Kaveri Seeds Company Ltd.,
Secunderabad
Development of biotic stress resistant rice through conjunct
use of bio-and hybrid technologies
(i) Nirmal Seeds Pvt. Ltd.,
Jalgaon
(ii) The Energy and
Resources Institute, New
Delhi
Kaveri Seeds Company Ltd.,
Secunderabad
(i) Krishidhan Seeds pvt.
Ltd., Jalna
(ii) ICRISAT,
Andhra
Pradesh
Development of nutritionally improved mustard (Brassica
juncea) varieties/hybrids having low erucic acid and low
glucosinolate content using marker assisted selection
(i) Advanta India Limited,
Secunderabad
(ii) Indian Agriculture
Research Institute, New
Delhi
(i) Sri Biotech Laboratories
India Ltd., Hyderabad
(ii) University of Delhi South
Campus, Delhi
Ankur Seeds Pvt. Ltd., Nagpur
Marker-assisted dissection of genetic basis of yield and
improving yield potential under drought stress in Maize
Genomics assisted accelerated product development of high
yeilding pigeonpea hybrids
RNAi
RNAi and other cuting edge technological interventions to
develop insect-pest diseases & viruses tolerant tomato
hybrids for Indian & International markets
Control of Shoot and Fruit Borer Insect Pest (Leucinodes
orbonalis Guenée) in Brinjal Through RNA interference
Third generation RNAi for engineering Tomato leaf curl
(ToLCV) and tospovirus (GBNV) resistance in tomato
(i) Nirmal Seeds Pvt. Ltd.,
Jalgaon
(ii) University of Delhi, South Development of viral resistant okra using RNAi approached
Campus, New Delhi
Secondary Agriculture
A P organics Ltd., Punjab
Project on value addition including potential neutraceuticals
from derivatives of rice
Others
96.
97.
98.
99.
(i) Sri Biotech Laboratories
India Ltd., Hyderabad
(ii) International
Crops
Research Institute for the
Semi-Arid
Tropics,
Hyderabad
(i) Chromous Biotech Pvt.
Ltd., Bangalore
(ii) IARI, New Delhi
(i) Saveer Biotech, Greater
Noida
(ii) Indian
Statistical
Institute, Kolkata
Tata Chemicals Limited,
Pune
Development of Actinomycetes based metabolites as
delivery systems for soil health management in Groundnut
Multiplexed Fast-PCR based detection kit for a group of
viruses affecting potato in India
Commercial Scale Production of Nanopesticides
Nanofungicides for Indian Agro-industry
and
Inorganic and polymer nano-composites for micronutrient
& pesticide delivery: Boosting crop health and yield.
Industrial
100.
101.
102.
Rossari Biotech Ltd., Mumbai
Viable Enzymes production using Agro waste/produce as raw
material of Industrial/Feed and health care use with large
viable Market/demand
Pvt., Single step extraction of cottonseed with miscella refining
Abhay Cotex India
Maharashtra
(i) Anil Ltd., Ahmedabad
Development of Value added Corn steep liquor and powder
(ii) National
Chemical suitable for food and fermentation industry upto pilot scale (1
TPD)
Laboratory (NCL), Pune
103.
Myko Tech Pvt. Ltd., Mapusa
Enhanced production of extra-cellular melanin from various
fungal sources for protection against UV and gamma
radiations
104.
Nagarjuna
Fertilizers Pvt.
Ltd., Hyderabad
Kumar
Organic
Product
Limited, Bangalore
International Panacea Ltd.,
New Delhi
Development of Technology Platform for Rare Sugar
Production
Sustainable and versatile microbial polymers: a bio-based
prospect for India
Developing Endosulphan degrading bacteria as a commercial
product
105.
106.
Energy
107
108
109
110
111
Avesthagen
Limited,
Bangalore
Richcore Lifesciences Pvt
Ltd., Bangalore
Nagarjuna Fertilizers and
Chemical Limited, Hyderabad
Bharat Petroleum Corporation
Limited, Greater Noida
Thermax Limited, Pune
Development of Self-glucogenic Pearl Millet adapted for
marginal lands
A process for Enhanced Ethanol Yield from Molasses
Fermentation
Transformational Technology Platform Development for
Biological Hydrogen
Butanol production from lignocellulosic biomass
Anaerobic Membrane Bioreactor (AnMBR) for Waste to
Energy Solutions
India
Glycols
Limited,
Kashipur
India Glycols Limited,
Kashipur
112
113
114
SPC Biotech, Hyderabad
Sea6 Energy, chennai
115
Praj matrix, Pune
116
117
(i) Praj Matrix, Pune
(ii) International Centre for
Genetic Engineering and
Biotechnology , New Delhi
Setting up a 10 ton Lignocellulosic biomass/day processing
plant to produce about 3000 Litre ethanol/day
Setting up 10 ton Lignocellulosic biomass/day+C128
processing plant to produce about 3000 Litre ethanol/day
(Phase – II: To run the plant in integrated continuous
mode)+C390
Bioconversion of Agricultural Waste from Mango kernel, to
Polylactic acid a bio-plastic
Cost-effective offshore biomass production and bioconversion to fuel - Bioenergy
Lignocellulosic
Biomass
to
Ethanol
Technology:
Simultaneous Saccharification and Fermentation
Development of novel cocktail of cellulolytic enzymes for
Deconstruction of Lignocellulosic feedstocks
Capacity Building through Infrastructure Support
Span
Surat
118
119
120
121
Diagnostics
Limited,
Establishment of cGMP compliant Bioprocess Facility for
large-scale production of Microbial antigens and
Monoclonal antibodies
Intas
Biopharmaceuticals
Private Limited, Ahmedabad
Gennova Biopharmaceuticals
Limited, Pune
Celestial Biologicals Ltd.,
Ahmedabad
Facility for high end structural and functional
characterization of protein therapeutics and peptides
State of art cGMP prodution facility metting regulatory
requirement for production of recombinant bio-therapeutics
Scale-up of Plasma Fractionatin Facility for High Value
Product
Bio-informatics
(i) Persistent Systems,
Maharashtra
(ii) Indian Institute of
Technology (IIT),
Mumbai
SanGeniX: A comprehensive next generation sequence (NGS)
(iii) Indian Institute of Science data analysis solution
Education and Research
(IISER), Pune
(iv) National
Bureau
of
Animal
Genetic
Resources
(NBAGR),
Haryana
122
SciGenome Labs Pvt.
Ltd., Cochin
123
High performance Computing Infrastructure