Printable Conference Program - Biology and Control of Nausea and
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Printable Conference Program - Biology and Control of Nausea and
Biology and Control of Nausea and Vomiting 2015 October 23-24, 2015 Biology and Control of Nausea and Vomiting 2015 will be held on the University of Pittsburgh Campus at The University Club, 123 University Place, Pittsburgh, Pennsylvania, USA University of Pittsburgh Cancer Institute Partner with UPMC Cancer Center Biology and Control of Nausea and Vomiting 2015 October 23-24, 2015 The University Club 123 University Place Pittsburgh, PA 15260 CONFERENCE OBJECTIVES Biology and Control of Nausea and Vomiting 2015 will bring together current leaders in the field of nausea and emesis research, including basic and translational scientists and clinicians who treat patients who pervasively suffer from these conditions. The proposed conference is intended to provide an optimal forum to discuss the biology and treatment of nausea and vomiting from a wide variety of perspectives, with the primary goal of formulating a consensus on new avenues of research and clinical approaches that will move the field forward. This primary goal is subdivided into five objectives: 1. Provide a forum for cross-disciplinary exchange of ideas to advance research on the biological mechanisms for nausea and vomiting. 2. Foster interactions for early-stage investigators to present research findings and connect with laboratories and more senior investigators working in the field of nausea and vomiting research. 3. Offer a forum where clinicians who treat patients with nausea and vomiting can exchange information. 4. Produce an overview and discussion of the major unresolved questions in nausea and vomiting biology and provide the latest methodology. 5. Broadly disseminate the findings and consensus of the meeting in peer-review manuscripts published in Autonomic Neuroscience: Basic and Clinical (Elsevier). TARGET AUDIENCE This program is designed for basic researchers and clinical investigators working in the field of nausea and vomiting. Information provided will also be useful for clinicians needing an up-to-date presentation of treatments for nausea and vomiting, particularly difficult-to-treat cases. CONFERENCE ADMINISTRATION Co-Organizers: Charles C. Horn, Ph.D. Associate Professor, Departments of Medicine and Anesthesiology Biobehavioral Oncology Program, University of Pittsburgh Cancer Institute University of Pittsburgh Pittsburgh, PA 15213 Bill J. Yates, Ph.D. Professor, Departments of Otolaryngology and Neuroscience University of Pittsburgh Pittsburgh, PA 15213 Planning Committee Members: Richard J. Gralla, M.D. Professor, Department of Medicine Director of Oncology Research for the North Bronx Healthcare Network Albert Einstein College of Medicine, Jacobi Medical Center Bronx, NY 10461 Kenneth L. Koch, M.D. Professor, Department of Medicine Chief, Section on Gastroenterology Wake Forest School of Medicine Winston-Salem, NC 27157 B. U. K. Li, M.D. Professor, Department of Medicine Director of Functional Gastroenterology Disorders for the Children’s Hospital of Wisconsin Medical College of Wisconsin Milwaukee, WI 53226 Charles M. Oman, Ph.D. Senior Research Engineer, Senior Lecturer Departments of Aeronautics and Astronautics Massachusetts Institute of Technology Cambridge, MA 02139 Henry P. Parkman, M.D. Professor, Department of Medicine Director of Gastrointestinal Motility Laboratory Lewis Katz School of Medicine, Temple University Philadelphia, PA 19140 Thangam Venkatesan, M.D. Associate Professor, Department of Medicine Division of Gastroenterology and Hepatology Medical College of Wisconsin Milwaukee, WI 53226 Susan W. Wesmiller, Ph.D., R.N. Assistant Professor, Department of Health Promotion & Development School of Nursing, University of Pittsburgh Pittsburgh, PA 15261 CONFERENCE SCHEDULE Day One: Friday, October 23, 2015 Registration, breakfast, platform sessions, the reception and poster session are scheduled in Ballroom B, located on the second floor of the University Club. Lunch and dinner are scheduled in Ballroom A, located on the first floor. 7:00 am Registration, breakfast, and poster setup 8:00 am Welcome remarks 8:10 am SESSION 1: PRODROMAL RESPONSES - DETECTING THE PRESENCE OF NAUSEA IN HUMANS AND ANIMAL MODELS Chairs: Charles Horn, PhD and Bill Yates, PhD – University of Pittsburgh 8:15 am “Determining the presence of nausea in emetic animals.” – Bill Yates, PhD, University of Pittsburgh 8:40 am “Time course of symptoms and signs in motion sickness.” – Charles Oman, PhD, Massachusetts Institute of Technology 9:05 am BREAK 9:15 am “Behavioral and physiological signs of visceral malaise in rats.” – Linda Rinaman, PhD, University of Pittsburgh 9:40 am SESSION 2: ACUTE-TO-CHRONIC NAUSEA AND VOMITING Chairs: Richard Gralla, MD – Albert Einstein College of Medicine, and Charles Horn, PhD – University of Pittsburgh 9:45 am “The pathobiology and palliation of acute/chronic chemotherapy-induced nausea and vomiting.” – Aminah Jatoi, MD, Mayo Clinic 10:10 am “Hyperemesis in pregnancy - What's new?” – Steve Caritis, MD, University of Pittsburgh 10:35 am BREAK 10:45 am “Biological pathways underlying nausea and vomiting in gastroparesis.” – William Hasler, MD, University of Michigan 11:10 am “Cellular basis for gastroparesis” – Gianrico Farrugia, MD, Mayo Clinic 11:45 am GROUP PHOTO - Terrace 12:00 pm LUNCH AT THE UNIVERSITY CLUB - Ballroom A 1:30 pm Plenary Lecture: “Anti-Emetic Research: Showing superiority over older drugs is key.” – John Rudd, PhD, The Chinese University of Hong Kong 2:15 pm SESSION 3: CYCLIC VOMITING SYNDROME RESEARCH SYMPOSIUM Chairs: Thangam Venkatesan, MD – Medical College of Wisconsin, and Klaus Bielefeldt, MD, PhD – University of Pittsburgh 2:20 pm “Cyclic vomiting syndrome: Phenotypic features to be explained by a pathophysiologic model(s).” – B.U.K. Li, MD, Medical College of Wisconsin 2:45 pm “Autonomic Control in Nausea – a mechanism-based analysis.” – Thomas Chelimsky, MD, Medical College of Wisconsin 3:10 pm BREAK 3:20 pm “Adult cyclic vomiting syndrome: A disorder of allostatic regulation?” – David Levinthal, MD, PhD, University of Pittsburgh 3:45 pm “Neuroimaging altered brain circuitries and neurotransmitter levels in cyclic vomiting syndrome.” – Vitaly Napadow, PhD, Massachusetts General Hospital 4:15 pm 4:20 pm 6:30 pm ADJOURNMENT OF ORAL SESSIONS SCIENTIFIC POSTER SESSION - Ballroom A RECEPTION AND DINNER - Ballroom A Day Two: Saturday, October 24, 2015 Breakfast and all meeting events are scheduled in Ballroom B, located on the second floor of the University Club. 7:00 am Breakfast 8:00 am SESSION 4: EARLY-STAGE INVESTIGATOR SYMPOSIUM Chairs: Charles Horn, PhD and Bill Yates, PhD – University of Pittsburgh 8:05 am “Identification of risk factors for adverse outcomes and recurrence of hyperemesis gravidarum (HG).” – Aromalyn Magtira, PhD, University of California, Los Angeles 8:20 am “The intracellular calcium mechanism involved in emesis in the least shrew.” – Weixia Zhong, PhD, Western University of Health Sciences 8:35 am “Hindbrain-forebrain communication in cisplatin-induced malaise.” – Amber Alhadeff, PhD, University of Pennsylvania 8:50 am BREAK 9:00 am “Vagal function and CNS control for nausea and their responses to transcutaneous electrical acupuncture in patients with Diabetic Gastroparesis.” – Gengqing Song, MD, PhD, Texas Tech University, Health Sciences Center 9:15 am “Endocannabinoid suppression of rat conditioned gaping: Insights into the role of visceral insular cortex 2-AG during acute nausea.” – Martin Sticht, PhD, University of Calgary, Canada 9:35 am SESSION 5: CLINICAL PANEL DISCUSSION – DIFFICULT CASES Chairs: Henry Parkman, MD – Temple University School of Medicine, and Kenneth Koch, MD – Wake Forest University School of Medicine 9:40 am “Management options for refractory nausea and vomiting in a patient with gastroparesis.” – Richard McCallum, MD, Texas Tech University, Health Sciences Center 9:55 am “Integrative medicine approach to managing nausea and vomiting.” – Linda Lee, MD, Johns Hopkins University 10:10 am “Finding Relief: Novel therapies for nausea in gastroparesis.” – Linda Nguyen, MD, Stanford University 10:25 am BREAK 10:35 am “Why patients still experience postoperative nausea and vomiting?” – Piotr Janicki, MD, Pennsylvania State University 10:50 am “Chemotherapy and emesis in lung cancer” – Richard Gralla, MD, Albert Einstein College of Medicine 11:10 am BACK TO THE FUTURE – CONFERENCE OVERVIEW Moderated by Charles Horn, PhD, Bill Yates, PhD, and Planning Committee – University of Pittsburgh (A synopsis of the major ideas presented during the conference and open discussion). 12:00 pm CONFERENCE ADJOURNMENT Lunch – local options on your own 12:15 pm SESSION 6: CYCLIC VOMITING SYNDROME ADULT GUIDELINES SESSION CLOSED SESSION Chairs: Thangam Venkatesan, MD and B.U.K Li, MD – Medical College of Wisconsin 5:00 pm GUIDELINE SESSION ADJOURNMENT – Ivy Room CONTINUING EDUCATION CREDIT The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The University of Pittsburgh School of Medicine designates this live activity for a maximum of 9.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded 0.9 continuing education units (CEU’s) which are equal to 9.5 contact hours. FACULTY DISLOSURE All individuals in control of the content for this activity including course directors, planning committee and faculty are required to disclose all relevant financial relationships with any proprietary entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients. No relevant financial relationships with commercial entities were disclosed by: Kathleen Adams; Amber Alhadeff, PhD; Klaus Bielefeldt, MD, PhD; Gianrico Farrugia, MD; Piotr Janicki, MD, PhD; Aminah Jatoi, MD; Linda Lee, MD; David Levinthal, MD, PhD; B.U.K. Li, MD; Aromayln Magtira, PhD; Richard McCallum, MD; Linda Nguyen, MD; Charles Oman, PhD; Jessica Poli; Linda Rinaman, PhD; John Rudd, PhD; Gengqing Song, MD, PhD; Martin Sticht, PhD; Thangam Venkatesan, MD; Susan Wesmiller, PhD; Bill Yates, PhD; Weixia Zhong, PhD The following information was disclosed: Steve Caritis, MD Grant/Research Support: ProStrakan; Duchesnay USA Thomas Chelimsky, MD Advisory Board: Lundbeck and Ironwood Richard Gralla, MD Consultant: Merck; Helsinn Healthcare SA; Tesaro; Eisai Oncology William Hasler, MD Grant/Research Support: Given Imaging, Inc. and Rhythm Pharmaceuticals, Inc. Consultant: Ironwood Pharmaceuticals Charles Horn, PhD Grant/Research Support: Medtronic Kenneth Koch, MD Grant/Research Support: Rhythm Pharmaceuticals Consultant: GlaxoSmithKline Stockholder: 3CPM Co. Henry Parkman, MD Grant/Research Support: Theravance Biopharma, Evoke Pharma, NIH Vitaly Napadow, PhD Consultant: GlaxoSmithKline Acknowledgement of Support We would like to extend a special thanks and appreciation to the following organizations for their generous support. Sponsorship • • • • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Cyclic Vomiting Syndrome Adult Guidelines Session Sponsored by the Cyclic Vomiting Syndrome Association in partnership with the American Neurogastroenterology and Motility Society Biobehavioral Oncology Program, University of Pittsburgh Cancer Institute University of Pittsburgh School of Medicine Center for Continuing Education in the Health Sciences University of Pittsburgh Cancer Institute Partner with UPMC Cancer Center Departments of Medicine (Division of Gastroenterology, Hepatology and Nutrition) and Otolaryngology, University of Pittsburgh School of Medicine Educational Grants • • • National Institutes of Health (NIH) ProStrakan Medtronic, Inc. Exhibitor • Merck Oncology DISCLAIMER STATEMENT The information presented at this CME program represents the views and opinions of the individual presenters, and does not constitute the opinion or endorsement of, or promotion by, the UPMC Center for Continuing Education in the Health Sciences, UPMC/University of Pittsburgh Medical Center or Affiliates and University of Pittsburgh School of Medicine. Reasonable efforts have been taken intending for educational subject matter to be presented in a balanced, unbiased fashion and in compliance with regulatory requirements. However, each program attendee must always use his/her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses. HOW TO OBTAIN CME CREDITS You will receive a credit designation form and day-of conference evaluations for completion during each day of the Biology and Control of Nausea and Vomiting 2015. To receive credit for participation, you will be expected to return the credit designation form and evaluation during each day of your attendance. POSTER PRESENTATIONS The poster session is scheduled from 4:20 PM - 6:30 PM on October 23rd in Ballroom B of the University Club. Posters can be placed on boards any time after 7 AM on October 23rd, and must be removed by 9:00 PM. Poster # 1 Title, Authors, and Affiliations Screening for Preoperative Risk Factors for Postoperative Nausea and Vomiting Archer MF1, Cipkala-Gaffin JA1, Alrawashdeh MO2 1 UPMC Shadyside, 2University of Pittsburgh, Pittsburgh, PA, USA 2 Effects of Gastrointestinal (GI) Inputs on Vestibular Signal Processing Bourdages GH, Demayo WM, McCall AA, Yates BJ Departments of Otolaryngology and Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA 3 Granisetron exposure and antiemetic efficacy in pregnant women treated for nausea and vomiting, are influenced by SNPs in CYP1A1, CYP3A4, CYP3A5 and ABCB1 genes. Bustos ML, Zhao Y, Chen H, Caritis SN and Venkataramanan R. Schools of Pharmacy and Medicine, University of Pittsburgh, Pittsburgh, PA, USA 4 Nausea during tilt, different pathophysiology – preliminary data Chelimsky T, Merritt M, Chelimsky G, Calawerts W, Barron A, Nugent M, Simpson P Medical College of Wisconsin and University of Wisconsin, Milwaukee and Madison, WI, USA 5 Associations between Peripheral Neuropathy, Nausea/Vomiting, and Life Satisfaction in Survivors of Ovarian Cancer: Effects of Persistent Vagal Neuropathy? Donovan HS, Campbell G, Horn CC, Hagan T, Gold MS, Sereika S, Bovbjerg DH. University of Pittsburgh School of Nursing; University of Pittsburgh Cancer Institute; University of Pittsburgh School of Medicine, Departments of Medicine (Gastroenterology, Hepatology, and Nutrition) and Anesthesiology; Center for Pain Research; Massachusetts General Hospital/Harvard Medical School; University of Pittsburgh Departments of Biostatistics, Epidemiology, and Clinical and Translational Science; University of Pittsburgh Departments of Psychiatry, Psychology, and Community Health Sciences, Pittsburgh, PA, USA 6 Robust Spectral Estimation of EGG Frequency Gharibans AA, Kim S, Coleman TP Department of Bioengineering, University of California, San Diego, CA, USA Page | 23 7 Effects of gastric electrical stimulation on emesis produced by distension of the stomach in the musk shrew Horn CC.1-4, Zirpel L.5, Sciullo M.1, and Rosenberg D.6 1 Biobehavioral Oncology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA; 2Department of Medicine: Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; 3 Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; 4 Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA; 5 Neuromodulation Global Research, Medtronic; 6 Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA 8 Hindbrain neuroinflammation mediates cisplatin-induced pica and anorexia in the rat Holland RA, Zimmer DJ, Hayes MR, De Jonghe BC University of Pennsylvania, Philadelphia, PA, USA 9 Influence of Sleep Deprivation and Motion on Motion Sickness and Cognitive and Motor Performance. Kaplan J.1, 3, Ventura J.1, DiZio P.1, 2, 3, Lackner JR.1, 2, 3 Ashton Graybiel Laboratory1, Volen Center for Complex Systems2, and Department of Psychology3, Brandeis University, Waltham, MA, USA 10 Sit Back and Relax: The Effects of Progressive Muscle Relaxation on Motion-Induced Nausea and Gastric Dysrhythmia. Levine ME, Puzino KM, & Crovello NJ. Department of Psychology, Siena College, Albany, NY, USA 11 Anxiety and Emotional Arousal Contribute to Nausea and Vomiting Associated with Gastroparesis and Cyclic Vomiting Syndrome Levinthal DJ 1, 2, Kirakossian D 1, Bielefeldt K 1, 22 1 University of Pittsburgh School of Medicine; 2 Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA 12 Multiple cortical areas influence the parasympathetic and sympathetic control of the rat stomach Levinthal DJ 1, 2, Strick PL 2, 3, 4 1 Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA; 2 Center for the Neural Basis of Cognition and Systems Neuroscience Institute, 3 Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA; 4 Veterans Affairs Medical Center, Pittsburgh, PA, USA Page | 24 13 Evidence for sudomotor component of vestibulo-sympathetic reflex during controlled Coriolis cross-coupling stimulation Nalivaiko E. 2, Bertolini G. 1, Romano F. 1, Straumann D. 1 1 Department of Neurology, University Hospital Zurich, Switzerland and School of Biomedical Sciences and Pharmacy, 2University of Newcastle, Australia 14 Multi-dimensional effects of vagal emetic activation on systemic physiology in the musk shrew Rosenberg D.1, 2, Lim A.1, 2, Gouilloux C.3, Sciullo M.1, and Horn CC2, 4-6 1 Department of Neuroscience, Univ. of Pittsburgh, Pittsburgh, PA, USA 2 Biobehavioral Oncology Program, Univ. of Pittsburgh Cancer Institute, Pittsburgh, PA, USA 3 AgroSup Dijon, France 4 Department of Medicine: Gastroenterology, Hepatology, and Nutrition, Univ. of Pittsburgh School of Medicine, Pittsburgh, PA, USA 5 Department of Anesthesiology, Univ. of Pittsburgh School of Medicine, Pittsburgh, PA, USA 6 Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA 15 Centrally-located Histamine H1 receptors are Involved in Motion-Induced Emesis in Suncus murinus (House Musk Shrew) Rudd JA1,2, Tu L1, Lu Z1, Dieser K3, Schmitt C3, Ingebrandt S3, Yeung CK, Nalivaiko E4, So RHY5, Andrews PLR6, Fan X7 1 School of Biomedical Sciences, Faculty of Medicine, and 2Brain and Mind Institute,The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China; 3 Department of Informatics and Microsystem Technology, University of Applied Sciences Kaiserslautern, Zweibrücken, Germany; 4 School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia; 5 Division of Biomedical Engineering, The Hong Kong University of Science and Technology, Hong Kong, China; 6Division of Biomedical Sciences, St George’s University of London, London, UK; 7Department of Statistics, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China 16 Suppression of gastric motility in motion sickness in Suncus murinus (house musk shrew) Takemi S, Sakata I, Sakai T Graduate School of Science and Engineering, Saitama University, Saitama, Japan 17 Prophylactic Medications for Cyclic Vomiting Syndrome Affect Gray Matter Density in Brain Areas Serving Autonomic Function Siwiec RM1, West JD2, Saykin AJ2, Samuel EA3, Kern MK3, Babaei A3, Venkatesan T3, Shaker R3 1 Indiana University, Division of Gastroenterology and Hepatology, Indianapolis, IN, USA 2 Indiana University, Department of Radiology and Imaging Sciences, Indianapolis, IN, USA 3 Medical College of Wisconsin, Division of Gastroenterology and Hepatology, Milwaukee, WI, USA Page | 25 18 Needleless Transcutaneous Electroacupuncture in Synchronization with Breathing for Treating Nausea in Idiopathic Gastroparetic Patients Song G1, Sarosiek I1, Bashashati M1, Sun Y1, Chen J2, 3, McCallum RW1 1 Internal Medicine Department, Texas Tech University Health Sciences Center, Paul L. Foster School of Medicine, El Paso, TX 79905. 2Johns Hopkins Center for Neurogastroenterology, Baltimore, MD, USA. 3Ningbo Pace Translational Medical Research Center, Beilun, Ningbo, China. 19 Sex, Postural Sway, Motion Sickness, and the Oculus Rift Munafo J, Stoffregen TA University of Minnesota, Minneapolis, MN, USA 20 iPad: Sex Differences in Body Sway and Motion Sickness Stoffregen TA, Li R, Diedrick MP University of Minnesota, Minneapolis, MN, USA 21 Psychiatric and Autonomic Comorbidities in Pediatric Cyclic Vomiting Syndrome Tarbell SE and Millar, MA Pediatric Mental Health Institute, Children’s Hospital Colorado, Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, USA 22 Hypnotherapy for nausea: Evidence for utility across multiple conditions Thorkelson GD University of Pittsburgh School of Medicine, Pittsburgh, PA, USA 23 Psychological profile of patients with cyclic vomiting syndrome Venkatesan T, Taranukha T, Seamon A, Wenzel C, Suresh Kumar V, Sahr N, Szabo A Medical College of Wisconsin, Milwaukee, WI, USA 24 Endocannabinoid–related lipids are increased during an episode of cyclic vomiting syndrome Venkatesan T, Zadvornova Y, Raff H, Hillard CJ Medical College of Wisconsin, Milwaukee, WI, USA 25 Effect of Endoscopic Pyloric Therapies for Patients with Obstructive Gastroparesis Wellington JL, Koch KL, Stuart, P. Department of Internal Medicine, Section on Gastroenterology Wake Forest School of Medicine, Winston-Salem, North Carolina Page | 26 26 Exploring the Multifactorial Nature of Postoperative Nausea and Vomiting in Women Following Breast Cancer Surgery Wesmiller SW, Bender CM, Sereika SM, Bovbjerg DH, Ahrendt GM, Bonaventura MA, and Conley, YP University of Pittsburgh School of Nursing, University of Pittsburgh Cancer Institute, and Magee Womens Hospital of the UPMC, Pittsburgh, PA, USA 27 Molecular, anatomical, and functional investigation of vagal sensory neurons Williams EK, Brust RD, Chang RB, Strochlic DE, Umans BD, Liberles SD Department of Cell Biology, Harvard Medical School, Boston, MA, USA Page | 27 Registered Attendees Name Affiliation Location Email Address Adams, Kathleen CVSA Durango, CO, USA [email protected] Alhadeff, Amber University of Pennsylvania Philadelphia, PA, USA [email protected] Baker, Ethan University of Pittsburgh Pittsburgh, PA, USA [email protected] Barile, Zachery University of Pittsburgh Pittsburgh, PA, USA [email protected] Bielefeldt, Klaus University of Pittsburgh Pittsburgh, PA, USA [email protected] Bourdages, George University of Pittsburgh Pittsburgh, PA, USA [email protected] Bovbjerg, Dana University of Pittsburgh Pittsburgh, PA, USA [email protected] Braken, Wendy Gastroparesis Patient Association for Cures and Treatment Etters, PA, USA [email protected] Brust, Rachael Harvard Medical School Boston, MA, USA [email protected] Caritis, Steve UPMC Pittsburgh, PA, USA [email protected] Chelimsky, Gisela Medical College of Wisconsin Milwaukee, WI, USA [email protected] Chelimsky, Thomas Medical College of Wisconsin Milwaukee, WI, USA [email protected] Chien, Yueh-Tyng Ironwood Pharmaceuticals Cambridge, MA, USA [email protected] Darmani, Nissar COMP/Western University Pomona, CA, USA [email protected] De Jonghe, Bart University of Pennsylvania Philadelphia, PA, USA [email protected] DeMayo, William UPMC Pittsburgh, PA, USA [email protected] Farr, Laura University of Pittsburgh Pittsburgh, PA, USA [email protected] Page | 57 Farrugia, Gianrico Mayo Clinic Rochester, MN, USA [email protected] Fera, Dean Merck North Wales, PA, USA [email protected] Gharibans, Armen UC San Diego San Diego, CA, USA [email protected] Gralla, Richard Albert Einstein College of Medicine New York, NY, USA [email protected] Hasler, William University of Michigan Health System Ann Arbor, MI, USA [email protected] Haston, Carissa Gastroparesis Patient Association for Cures and Treatment Etters, PA, USA [email protected] Hobi, Lauren UPMC Pittsburgh, PA, USA [email protected] Holland, Ruby University of Pennsylvania Philadelphia, PA, USA [email protected] Horn, Charles University of Pittsburgh Pittsburgh, PA, USA [email protected] Issenman, Robert McMaster University Hamilton, ON, CAN [email protected] Jaime-Lara, Rosario University of Pennsylvania Philadelphia, PA, USA [email protected] Janicki, Piotr Penn State University Hershey, PA, USA [email protected] Jatoi, Aminah Mayo Clinic Rochester, Minnesota, USA [email protected] Joyce, Martin Merck North Wales, PA, USA Kaplan, Janna Brandeis University West Newton, MA [email protected] Kirakossian, David University of Pittsburgh Pittsburgh, PA, USA [email protected] Klein, Sara University of Pittsburgh Pittsburgh, PA, USA [email protected] Koch, Ken Wake Forest Univ. School of Medicine Winston Salem, NC, USA [email protected] Page | 58 Kovacic, Katja Medical College of Wisconsin Brookfield, WI, USA [email protected] Kuo, Braden Massachusetts General Hospital Boston, MA, USA [email protected] Kurtz, Caroline Ironwood Pharmaceuticals Cambridge, MA, USA [email protected] Lee, Linda Johns Hopkins Baltimore, MD, USA [email protected] Levine, Max Siena College Loudonville, NY, USA [email protected] Levinthal, David University of Pittsburgh Pittsburgh, PA, USA [email protected] Li, B.U.K. Medical College of Wisconsin Milwaukee, WI, USA [email protected] Li, Ruixuan University of Minnesota Saint Paul, MN, USA [email protected] Lockard, Danielle UPMC Pittsburgh, PA, USA [email protected] Longlong, Tu The Chinese University of Hong Kong Hong Kong, China [email protected] Lucot, James Wright State University Dayton, OH, USA [email protected] Magtira, Aromalyn UCLA Los Angeles, CA, USA [email protected] Mathis, Hannah University of Pittsburgh Pittsburgh, PA, USA [email protected] McCallum, Richard Texas Tech University Health Sciences Center El Paso, TX, USA [email protected] Miller, Alan Amster Rothstein & Ebenstein, LLP New York, NY, USA [email protected] Miller, Derek University of Pittsburgh Pittsburgh, PA, USA [email protected] Munafo, Justin University of Minnesota Minneapolis, MN, USA [email protected] Murphy, Karen GlaxoSmithKline King of Prussia, PA, USA [email protected] Page | 59 Napadow, Vitaly Harvard University Cambridge, MA, USA [email protected] Nguyen, Linda Stanford University Stanford, CA, USA [email protected] Nino, Antonio GlaxoSmithKline King of Prussia, PA, USA [email protected] Olivos, Diana University of Pittsburgh Pittsburgh, PA, USA [email protected] Oman, Charles Massachusetts Institute of Technology Cambridge, MA, USA [email protected] Parkman, Henry Temple University Philadelphia, PA, USA [email protected] Poli, Jessica University of Pittsburgh Pittsburgh, PA, USA [email protected] Rinaman, Linda University of Pittsburgh Pittsburgh, PA, USA [email protected] Roberge, Mary University of Pittsburgh, School of Nursing Pittsburgh, PA, USA [email protected] Romano, Fausto University Hospital Zurich Zurich, Switzerland [email protected] Rosenberg, David University of Pittsburgh Pittsburgh, PA, USA [email protected] Rudd, John Chinese University of Hong Kong Hong Kong, China [email protected] Sakata, Ichiro Saitama University Saitama, China [email protected] Schafer, Claire University of Pittsburgh Pittsburgh, PA, USA [email protected] Sciullo, Michael University of Pittsburgh Pittsburgh, PA, USA [email protected] Shepman, Bruce Merck North Wales, PA, USA Simon, Jacqueline University of Pittsburgh Pittsburgh, PA, USA [email protected] Siwiec, Robert Indiana University School of Medicine Indianapolis, IN, USA [email protected] Page | 60 Song, Gengqing Texas Tech University Health Sciences Center El Paso, TX, USA [email protected] Sticht, Martin University of Guelph Guelph, Ontario [email protected] Takemi, Shota Saitama University Saitama, Japan [email protected] Tarbell, Sally University of Colorado Anschutz Medical Campus Boulder, CO, USA [email protected] Travis, Leanna University of Pittsburgh Pittsburgh, PA, USA [email protected] Medical College of Wisconsin Milwaukee, WI, USA [email protected] Tucson, AZ, USA [email protected] Venkatesan, Thangam Vestal, Michelle Walters, Kyra Tesaro Gilbertsville, PA, USA [email protected] Wang, Catherine GlaxoSmithKline King of Prussia, PA, USA [email protected] Wellington, Jennifer Wake Forest Winston Salem, NC, USA [email protected] Wesmiller, Susan Univeristy of Pittsburgh Pittsburgh, PA, USA [email protected] Williams, Erika Harvard Medical School Boston, MA, USA [email protected] Wong, Doris ProStrakan Sunnyside, NY, USA [email protected] Yates, Bill University of Pittsburgh Pittsburgh, PA, USA [email protected] Zhong, Weixia Western University Health Sciences Pomona, CA, USA [email protected] Page | 61 Wyndham University Club 500 feet 100 m © 2015 HERE Restaurants & Bars - Oakland Primanti Bros. 412.621.4444 | 3803 Forbes Ave Local chain known for sandwiches piled-high with coleslaw, fries & meat has a casual pub setting. 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