Chapter 2: Chemistry, Matter, and Life
Transcription
Chapter 2: Chemistry, Matter, and Life
Cohen: Memmler’s The Human Body in Health and Disease Phases of Respiration Respiration: • Process of obtaining oxygen from environment and delivering it to cells Phases of Respiration Chapter 18: The Respiratory System 1. Pulmonary ventilation – between air and lungs 2. External gas exchange – between lungs and blood 3. Gas transport in the blood – carries oxygen and CO2 4. Internal gas exchange – between blood and tissue cells Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 18-1 Overview of respiration. From which side of the heart does blood leave to travel to the lungs? To which side does it return? Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Structures of the Respiratory System The Nasal Cavities – open spaces between roof of mouth and cranium Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 18-2 The respiratory system. What organ is located in the medial depression of the left lung? Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Structures of the Respiratory System The Pharynx – the throat; carries air to lungs and food to stomach • Nostrils (nares) – air enters here – Nasopharynx - Superior portion near nose • Nasal septum –partition that divides nostrils – Oropharynx - Middle portion near mouth • Conchae – shell-like projections inside cavity – Laryngeal pharynx - Inferior portion near larynx • Air is Filtered, Warmed, Moistened by mucus membranes Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins 1 Cohen: Memmler’s The Human Body in Health and Disease Structures of the Respiratory System Cohen: Memmler’s The Human Body in Health and Disease Figure 18-3 The larynx. The Larynx • Cartilage framework between pharynx and trachea; (Adam’s apple) – Epiglottis – flap that closes over esophagus – Vocal cords – used for speech as air flows over them – Glottis – opening in the vocal cords Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Structures of the Respiratory System Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Structures of the Respiratory System The Trachea The Lungs • Takes air to lungs; horseshoe-shaped rings of cartilage to keep shape Located on either side of mediastinum The Bronchi • Two primary branches that enter the lungs from the trachea • Right lung – divided into three lobes that match bronchi • Left lung – divided into two lobes that match bronchi – Bronchial tree branches of the bronchi into the lungs – Bronchioles – smaller, narrower branches – Terminal bronchioles – end of the branches • Alveoli – air sacs at the end of bronchioles – Thin walls – one cell thick to allow gases to pass – Surface area 60 square meters (volleyball court) Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Structures of the Respiratory System Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease The Process of Respiration The Pleurae Pulmonary Ventilation • Diaphragm – muscle that sits below lungs • Inhalation (inspiration) is active phase in which the diaphragm and chest muscles contract • Parietal pleura - connective tissue coverings of the lungs – Surfactant – substance to reduce the surface tension of fluids in lungs; allows lungs to expand • Exhalation (expiration) is passive phase; muscles relax Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins 2 Cohen: Memmler’s The Human Body in Health and Disease Figure 18-6 Pulmonary ventilation. Cohen: Memmler’s The Human Body in Health and Disease The Process of Respiration Pulmonary Ventilation • Lung volumes – Tidal volume – regular relaxed breathing – Residual volume – volume of air left in lungs – Inspiratory reserve volume – breathing in beyond normal breath – Expiratory reserve volume – breathing out beyond normal breath – Vital capacity– volume breathed out after deep breath What muscles are located between the ribs? Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 18-8 A spirogram. – Functional residual capacity- volume left after normal breath – Total capacity- total volume of air in lungs Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease The Process of Respiration Gas Exchange • External exchange— between alveoli and capillaries – Oxygen leaves alveoli and enters capillaries – Carbon dioxide leaves capillaries and enters alveoli • Internal exchange— between body tissue and capillaries – Oxygen leaves capillaries and enters tissue – Carbon dioxide leaves tissue and enters capillaries What lung volume cannot be measured with a spirometer? Which lung capacities cannot be measured with a spirometer? Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Figure 18-9 Gas exchange. Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Process of Respiration Transport of Oxygen • Most oxygen is transported in blood by hemoglobin. Transport of Carbon Dioxide • 10% is dissolved in plasma and fluid in red blood cells • 15% is combined with protein of hemoglobin and plasma proteins • 75% dissolves in blood fluids and is converted to bicarbonate ion Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins 3 Cohen: Memmler’s The Human Body in Health and Disease Figure 18-10 Regulation of respiration. Nervous Control – your brain is in control Cohen: Memmler’s The Human Body in Health and Disease Regulation of Respiration Chemical Control • Central chemoreceptors • Control center is located in medulla and pons of brain stem – Located near medulla • Fibers extend from the spinal cord, through phrenic nerve to diaphragm and chest muscles • Peripheral chemoreceptors Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Regulation of Respiration – Respond to raised CO2 level (hypercapnia) – Located in neck and aortic arch – Respond to oxygen level considerably below normal • Other factors such as pain or emotional responses can affect breathing patterns Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Regulation of Respiration Abnormal Ventilation Breathing Patterns • Hyperventilation Measured in breaths per minute – High oxygen level and low CO2 level (hypocapnia) • Adults: 12 to 20 bpm – Increases blood pH • Children: 20 to 40 • Hypoventilation • Infants: more than 40 – Insufficient air in alveoli – Decreases blood pH Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Regulation of Respiration Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Cohen: Memmler’s The Human Body in Health and Disease Regulation of Respiration Some Terms for Altered Breathing Results of Inadequate Breathing • Hyperpnea- increase in depth and rate • Cyanosis – bluish color due to insufficient O2 • Hypopnea- decrease in depth and rate • Hypoxia – lower than normal oxygen in tissues • Tachypnea- excessive rate, as in exercise • Hypoxemia – lower than normal oxygen in blood • Apnea – temporary cessation for short periods • Suffocation- cessation of breathing due to some blockage Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins 4