Hip dysplasia in young adults - Nasjonalt Register for Leddproteser
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Hip dysplasia in young adults - Nasjonalt Register for Leddproteser
Hip dysplasia in young adults ,QJYLOGYVWHE¡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historical overview ................................................................................................................ 19 6.2.2 Normal development of the hip joint ......................................................................................... 22 6.2.3 Definition and terminology ....................................................................................................... 24 6.2.4 Epidemiology ............................................................................................................................ 25 6.2.5 Aetiology ................................................................................................................................... 26 6.2.6 Natural history of hip dysplasia ................................................................................................ 29 6.2.7 Diagnosis in newborns and infants ........................................................................................... 31 6.2.8 Diagnosis in adolescents and adults ......................................................................................... 37 6.2.9 Treatment options ..................................................................................................................... 39 267(2$57+5,7,62)7+(+,3 7+(125:(*,$1$57+523/$67<5(*,67(5 7+(0(',&$/%,57+5(*,675<2)125:$< 7+(%(5*(1%,57+&2+257678'< 6.6.1 The 1988-1990 Hip Cohort ....................................................................................................... 47 6.6.2 The 1989 Hip Project ................................................................................................................ 49 $,062)7+(678'< 0(7+2'6 '$7$ 8.1.1 Paper I ...................................................................................................................................... 54 8.1.2 Paper II ..................................................................................................................................... 55 8.1.3 Paper III.................................................................................................................................... 55 8.1.4 Paper IV .................................................................................................................................... 55 287&20(0($685(6 8.2.1 Radiographic parameters associated with hip dysplasia at skeletal maturity .......................... 56 8.2.2 EQ-5D ....................................................................................................................................... 59 8.2.3 WOMAC Osteoarthritis Index ................................................................................................... 60 8.2.4 The Beighton score ................................................................................................................... 60 ',*,7$/0($685(0(17352*5$00( 67$7,67,&$/$1$/<6(6 8.4.1 Statistical software .................................................................................................................... 64 $33529$/6 6800$5<2)3$3(56,,9 3$3(5, 3$3(5,, 3$3(5,,, 3$3(5,9 *(1(5$/',6&866,21 0(7+2'2/2*,&$/&216,'(5$7,216 10.1.1 Study design .............................................................................................................................. 68 10.1.2 Health registry studies – pros and cons .................................................................................... 71 10.1.3 Quality of register data ............................................................................................................. 73 10.1.4 Patient reported outcome measures .......................................................................................... 76 10.1.5 Reproducibility in measurement studies .................................................................................... 79 10.1.6 Measurement error and measurement uncertainty ................................................................... 80 10.1.7 Defining hip dysplasia at skeletal maturity ............................................................................... 83 10.1.8 Ethics ......................................................................................................................................... 96 5(68/76 10.2.1 Is the screening programme for hip dysplasia sufficient? ......................................................... 97 10.2.2 Treatment options for hip dysplasia ........................................................................................ 101 10.2.3 Outcome measures in hip dysplasia patients with a THR ....................................................... 103 10.2.4 Repeatability of hip dysplasia measurements.......................................................................... 105 10.2.5 Occurrence of hip dysplasia .................................................................................................... 109 &21&/86,216 ,03/,&$7,216$1')8785(5(6($5&+ 6285&(62)'$7$ (55$7$ $33(1',&(6 3$3(56,,9 1. 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A positive sign indicates that a dislocated hip is reduced. Figure 5 Barlow’s manoeuvre is another test used to examine the stability of the hip. If the hip can be dislocated by manipulation, the test is positive. A B Figure 6 Six-month-old girl with hip dislocation in the right hip presented with (A) reduced abduction and (B) a positive heel-buttock test. 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DEGXFWLRQ LV VHHQ ZKHQ WKH KLS LV IOH[HG GHJUHHV $URXQG KDYH ELODWHUDO G\VSODVLD ZKLFK PDNH WKH GLDJQRVLVPRUHWURXEOHVRPHDVWKHDV\PPHWU\PLJKWEHPLVVLQJDQGWKHDEGXFWLRQLV UHGXFHG LQ ERWK VLGHV +RZHYHU D WRWDO DEGXFWLRQ RI OHVV WKDQ LQGLFDWHV D SRVVLEOH ELODWHUDO KLS GLVORFDWLRQ 8QLODWHUDO UHGXFHG DEGXFWLRQ FDQ DOVR EH GHWHFWHG ZLWKWKH³KHHOEXWWRFNWHVW´)LJXUH%,QDQRUPDOKLSWKHOLQHEHWZHHQWKHVROHRI WKHIHHWDQGWKHJOXWHDOFOHIWLVFRQWLQXRXV,QWKHFDVHRIXQLODWHUDOUHGXFHGDEGXFWLRQ WKLVOLQHLVLQWHUUXSWHGDQGWKHIHHWGHYLDWHWRWKHKHDOWK\VLGH A B Figure 7 Asymmetric skin folds in a six-month-old girl with hip dislocation in the right hip (A) and leg length discrepancy illustrated with a positive Galeazzi sign (B). 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B A Femoral head Beta angle Femoral head Cartilage roof triangle Cartilaginous roof line Bony rim Baseline Alpha angle Acetabular roof line Figure 9 The coronal standard view through the centre of the acetabulum, showing the bony acetabulum, the bony rim and the cartilage roof triangle (A). The alpha (Į) and beta (ß) angles are illustrated in B. The baseline passes through the plane of the ileum. The acetabular roof line runs along the plane of the bony acetabular convexity and the cartilaginous roof line (inclination line) passes from the lateral end of the acetabulum to the labrum, parallel to the cartilaginous roof. 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Rosendahl’s modification of Graf’s method92. Type Description Normal Normal hip. A well-modelled bony acetabular roof with a sharp lateral edge and a narrow cartilaginous rim. The alpha angle 60Û Immature Adequately formed bony acetabular roof with a rounded lateral margin and a wide cartilaginous rim, i.e. a physiological retardation of the acetabular rim. The alpha angle 50-59ÛÛĮÛ Dysplastic Mild: Deficiently formed bony acetabular roof with a rounded to flattened lateral margin and a wide cartilaginous rim, i.e. a maturational deficit. The alpha angle between 43Û and 50ÛÛĮÛ Corresponds to Graf type IIc Severe: Poorly formed bony acetabular roof with a flattened lateral margin and a wide cartilaginous rim. 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High dislocation Wiberg’s CE angle>20Û IV More than 100% subluxation Subluxation V False acetabulum VI Redislocation RQ WKH EDVLV RI DFHWDEXODU GHSWK DQG IHPRUDO KHDG ORFDWLRQ DW VNHOHWDO PDWXULW\ +DUWRILODNLGLV KDV DOVR SURSRVHG D VFRULQJ V\VWHP DVVHVVLQJ WKH DFHWDEXODU DEQRUPDOLW\DQGFODVVLI\LQJWKHKLSVLQWRWKUHHJURXSV 6.2.9 Treatment options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igure 10 The Frejka pillow is the standard treatment for newborns with hip dysplasia in Norway. 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igure 11 Preoperative traction treatment for a girl with a dislocated hip that was not reducible. WUHDWPHQWRIKLSG\VSODVLDLVWRKDYH D KLS DV DQDWRPLFDOO\ QRUPDO DV SRVVLEOH E\ VNHOHWDO PDWXULW\ Figure 12 Hip spica cast for a girl with hip dislocation in the right hip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KLS UHSODFHPHQWV DIWHU KLS G\VSODVLD DUH JHQHUDOO\ JRRG ,Q KLS UHVXUIDFLQJ D PHWDO FXS LV SODFHG RYHU WKH IHPRUDO KHDG ZKLOH D PDWFKLQJPHWDOFXSLVSODFHGLQWKHDFHWDEXOXPEXWGXHWRSRRUFOLQLFDOUHVXOWVWKLV PHWKRGKDVQRZEHHQDERXQGHG Figure 13 Radiograph of a 32-year-old female with a total hip replacement on the left side due to hip dysplasia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¶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|QQLV &ODVVLILFDWLRQ RI 2VWHRDUWKULWLV E\ UDGLRJUDSKLF FKDQJHV WKH .HOOJUHQ/DZUHQFH VFDOH DQG WKH &URIW FODVVLILFDWLRQ7DEOH 7KH WUHDWPHQW RSWLRQV IRU KLS RVWHRDUWKULWLV GHSHQG RQ WKH SDWLHQW¶V V\PSWRPV DJH DQGJHQHUDOKHDOWKFRQGLWLRQLQDGGLWLRQWRWKHGLVWULEXWLRQRIWKHDUWKULWLV,QJHQHUDO LW LV DGYLVHG WR IROORZ D WUHDWPHQW S\UDPLG ZKHUH DOO SDWLHQWV VKRXOG EH RIIHUHG LQIRUPDWLRQ DQG JXLGDQFH RQ SK\VLFDO DFWLYLW\ DQG LQ VRPH FDVHV RQ ZHLJKW ORVV 6RPH ZRXOG EHQHILW IURP SK\VLFDO WKHUDS\ SDLQ NLOOHUV DQGRU QRQVWHURLGDO DQWL Table 3 Different classification systems for hip osteoarthritis Grade Tönnis classification 0 No signs of RVWHRDUWKULWLV 1 Slight narrowing of joint space, slight lipping at joint margin, slight sclerosis of femoral head or acetabulum Small cysts in femoral head or acetabulum, increased narrowing of joint space, moderate loss of sphericity of femoral head Large cysts, severe narrowing or obliteration of joint space, severe deformity of femoral head, avascular necrosis 2 3 4 5 Kellgren-Lawrence classification No changes of osteoarthritis Croft classification No changes of osteoarthritis Possible narrowing of joint space medially and possible osteophytes around femoral head Osteophytosis only Definite narrowing of joint space inferiorly, definite osteophytes and slight sclerosis Joint space narrowing only Marked narrowing of joint space, slight osteophytes, some sclerosis and cyst formation and deformity of femoral head and acetabulum Gross loss of joint space with sclerosis and cysts, marked deformity of femoral head and acetabulum and large osteophytes. Two of osteophytosis, joint space narrowing, subchondral sclerosis and cyst formation. Three of osteophytosis, joint space narrowing, subchondral sclerosis, and cyst formation. As in grade 4, but with deformity of femoral head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¶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¶V SDUHQWV FRPSOLFDWLRQV GXULQJ SUHJQDQF\ RU ELUWK FKLOG¶V KHDOWK LQFOXGLQJ KLS LQVWDELOLW\ PDWHUQDO KHDOWK DQG PDWHUQDO RFFXSDWLRQ DQG VPRNLQJ KDELWV DUH UHFRUGHG,Q'HFHPEHUWKHRULJLQDOUHJLVWUDWLRQIRUPIURP$SSHQGL[ ZDVUHSODFHGE\DQHZRQH$SSHQGL[$WWKHVDPHWLPHWKHUHJLVWHUFKDQJHGLWV FRGLQJV\VWHPIURPWKH,QWHUQDWLRQDO&ODVVLILFDWLRQRI'LVHDVHV9HUVLRQ,&'WR 9HUVLRQ,&' ,QIRUPDWLRQUHJDUGLQJKLSLQVWDELOLW\KDVEHHQUHFRUGHGVLQFHFRPPHQFHPHQW,&' FRGHV UHIOHFWLQJ KLS LQVWDELOLW\ ZHUH ³dislocation of the hip” “dysplasia of the hip” DQG “positive Ortolani test” 7KH QHZ IRUP LQWURGXFHG LQ LQFOXGHG D ER[ IRU “dysplasia of the hip treated with Frejka pillow” 2WKHU GLDJQRVHVLQWKHFDWHJRU\RIFRQJHQLWDODEQRUPDOLWLHVRIWKHKLS4±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he 1988-1990 Hip Cohort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¶V PHWKRG ,QGLFDWLRQV IRU WUHDWPHQW ZHUH GLVORFDWDEOHGLVORFDWHG KLSV RU VHYHUH VRQRJUDSKLF G\VSODVLD LUUHVSHFWLYH RI FOLQLFDO RU VRQRJUDSKLF VWDELOLW\ +LSV ZLWK D PLOGO\ G\VSODVWLF PRUSKRORJ\ Į ZHUH WUHDWHG LI WKH\ ZHUH DOVR FOLQLFDOO\ RU VRQRJUDSKLFDOO\ GLVORFDWDEOHGLVORFDWHG ,I WKH KLSV ZHUH VRQRJUDSKLFDOO\ LPPDWXUH Į RU PLOGO\ G\VSODVWLF Į EXW FOLQLFDOO\ VWDEOH WKH\ KDG FOLQLFDO DQG VRQRJUDSKLFVXUYHLOODQFHHYHU\IRXUWKZHHNXQWLOQRUPDOLVDWLRQRUXQWLOWUHDWPHQWZDV LQLWLDWHG GXH WR ODFN RI LPSURYHPHQW %DELHV ZLWK QRUPDO KLSV EXW ZLWK ULVN IDFWRUV IRU KLS G\VSODVLD ZHUH UHIHUUHG IRU D UDGLRJUDSK RI WKH KLSV DW PRQWKV RI DJH $GGLWLRQDOO\ DOO FKLOGUHQ LQ 1RUZD\ DUH UHJXODUO\ FOLQLFDOO\ H[DPLQHG GXULQJ WKHLU ILUVWWZR\HDUVRIOLIHDVSDUWRIWKHQDWLRQDOKHDOWKSURJUDPPH)ROORZXSFOLQLFDODQG 6HWWLQQKHU All born at HUS in the period January 1988-June 1990 1988 + 1990 1989 Study base RCT (The 1988-1990 Hip Cohort) Excluded: - Birth weight <1500 g or severe disease/malformations (N = 103) - Declined to participate (N = 5) Included RCT (The 1988-1990 Hip Cohort) N = 11 925 1988 N = 4 739 1989 N = 5 014 1990 N = 2 172 Excluded: - Normal neonatal hip exam 3 screening groups Universal US Selective US Only clinical screening N = 3 613 N = 4 388 N = 3 924 Pathological neonatal hip exam (clinical and/or US) N = 569 Study base maturity review (February 2007-March 2009) (The 1989 Hip Project) N = 5637 1988 + 1990 N = 569 1989 N = 5 068 Excluded (N = 1 128): - Not resident in HUS catchment area* - emigrated/not found - dead Invited to maturity review (The 1989 Hip Project) N = 4 509 1988 + 1990 N = 503 1989 N = 4 006 Attended maturity review (The 1989 Hip Project) N = 2 390 1988 + 1990 N = 503 1989 N = 2 081 Excluded after attendance: - Missing radiographs or suboptimal quality of radiographs (N = 9) - Not born in 1989 (N = 503) Universal US Selective US ~27% ~33 % Only clinical screening ~40 % Included for analysis in Paper IV N = 2 072 Figure 14 Flow of participants in the 1989 Bergen Hip Cohort Study. HUS: Haukeland University Hospital; US: ultrasound; RCT: Randomised Clinical Trial; N: Number UDGLRORJLFDO GDWD RQ WKRVH GLDJQRVHG DV KDYLQJ KLS G\VSODVLD RU RWKHU KLS GLVRUGHUV ZHUHFROOHFWHGRQVXEMHFWVDWDOODJHV 2XWFRPH PHDVXUHV IRU WKH 5&7 ZHUH UDWHV RI ODWHGHWHFWHG G\VSODVLD DJH ! PRQWK DV GHILQHG E\ WKH DFHWDEXODU LQGH[ RI 7|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he 1989 Hip Project ,QWKHSHULRG)HEUXDU\WR0DUFKDOOWKRVHERUQDW+DXNHODQG8QLYHUVLW\ +RVSLWDOLQQ DVZHOODVWKRVHERUQLQDQGLQZKRPQHRQDWDO KLSDEQRUPDOLWLHVZHUHGHWHFWHGQ JLYLQJDVDPSOHRIZHUHLQYLWHGWRD IROORZXSVWXG\RIWKHLUKLSV3HUVRQVZKRZHUHGHDGKDGHPLJUDWHGRUZHUHOLYLQJ RXWVLGHDGHILQHGDUHDRI%HUJHQDQGVXUURXQGLQJVZHUHH[FOXGHGQ 7KHDUHD ZDVGHILQHGDVWKHFDWFKPHQWDUHDRI+DXNHODQG8QLYHUVLW\+RVSLWDOZKLFKLQFOXGHG %HUJHQ6DPQDQJHU2V$XVWHYROO6XQG)MHOO$VN¡\2VWHU¡\0HODQG\JDUGHQ 5DG¡\/LQGn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uestionnaires $TXHVWLRQQDLUHZDVDWWDFKHGWRWKHLQYLWDWLRQOHWWHUZKLFKSDUWLFLSDQWVZHUHDVNHGWR FRPSOHWHSULRUWRWKHDSSRLQWPHQW7KLVFRQWDLQHGTXHVWLRQVUHJDUGLQJKLSSUREOHPV LQ FKLOGKRRG KLS SUREOHPV LQ WKH IDPLO\ DQG WKHLU SDUHQWV¶ KHLJKW $SSHQGL[ $ VHFRQGTXHVWLRQQDLUHZDVILOOHGLQRQDUULYDOZKLFKFRQVLVWHGRIWKUHHSDUWVLQFOXGLQJ VWDQGDUGLVHG TXHVWLRQQDLUHV RQ TXDOLW\ RI OLIH (4' ZZZHXURTRORUJ DQG KLS SUREOHPV:20$&ZZZZRPDFRUJ$SSHQGL[ Radiological examinations 7KH UDGLRORJLFDO H[DPLQDWLRQV ZHUH SHUIRUPHG E\ D VLQJOH VSHFLDOO\ WUDLQHG UDGLRJUDSKHU XVLQJ D ORZGRVH GLJLWDO UDGLRJUDSK\ WHFKQLTXH 'LJLWDO'LDJQRVW 6\VWHP YHUVLRQ 3KLOLSV 0HGLFDO 6\VWHPV +DPEXUJ *HUPDQ\ $ VWULFWO\ VWDQGDUGLVHG SURWRFRO ZDV IROORZHG %R\V ZHUH RIIHUHG D JRQDGDO VKLHOG )HPDOHV A B Figure 15 Two radiographs were obtained: (A) one erect anteroposterior view and (B) one supine frog-leg view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linical examination 7KH FOLQLFDO H[DPLQDWLRQ )LJXUH ZDV SHUIRUPHG E\ RQH RI ILYH SK\VLFLDQV EOLQGHG WR WKH UHVXOWV RI WKH TXHVWLRQQDLUH DQG UDGLRJUDSKV 2QH H[SHULHQFHG VHQLRU RUWKRSDHGLFVXUJHRQ/%(VWDQGDUGLVHGWKHFOLQLFDOH[DPLQDWLRQDQGWUDLQHGWKHIRXU OHVV H[SHULHQFHG SK\VLFLDQV $ VWDQGDUGLVHG SURWRFRO LQFOXGLQJ KHLJKW ZHLJKW A B C D Figure 16 Clinical examination of the hip: (A) external rotation, (B) internal rotation, (C) abduction, and (D) extension. 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METHODS 8.1 DATA 7KLV WKHVLV LV EDVHG RQ UHJLVWU\ GDWD IURP WKH 1RUZHJLDQ $UWKURSODVW\ 5HJLVWHU 1$53DSHUV,,,WKH0HGLFDO%LUWK5HJLVWU\RI1RUZD\0%513DSHU,DQG FOLQLFDOGDWDIURPWKH+LS3URMHFW3DSHUV,,,,9 8.1.1 Paper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orwegian Arthroplasty Medical Birth Registry Register (NAR) of Norway (MBRN) All total hip replacements All newborns born after 1967 after 1987 N = 106 716 prostheses N = 2 218 596 newborns NAR ļ MBRN All persons born after 1967 with a primary total hip replacement (inserted after 1987) N = 633 prostheses in 442 patients Figure 17 The two national registries, the Norwegian Arthroplasty Register (NAR) and the Medical Birth Registry of Norway (MBRN), were linked using the national personal identification number. In total 442 persons were recorded in both registries. 8.1.2 Paper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p/HJJ 3HUWKHV¶ GLVHDVH &/3 RU D VOLSSHG FDSLWDO IHPRUDO HSLSK\VLV 6&)( ZH DOVR UHFRUGHG GDWD DQG V\PSWRPV DW WKH WLPH RI GLDJQRVLV RI WKH KLS GLVHDVH DQG DQ\ WUHDWPHQWJLYHQIRUWKHKLSGLVRUGHUSULRUWRWKHLUWRWDOKLSUHSODFHPHQW$SSHQGL[ 8.1.3 Paper III 7KH WKLUG VWXG\ FRPSULVHG FRQYHQWLRQDO $3 SHOYLF UDGLRJUDSKV IURP SDUWLFLSDQWV LQ WKH +LS 3URMHFW $OO LPDJHV ZHUH PHDVXUHG ERWK LQ D GLJLWDO PHDVXUHPHQW SURJUDPPH$GXOWB''+,RZD+RVSLWDODQG&OLQLFV,RZD86$DQGLQWKHVWDQGDUG PDQQHU LQ $JID:HE 7KLV VWXG\ ZDV SHUIRUPHG WR YDOLGDWH WKH QHZ GLJLWDO PHDVXUHPHQW SURJUDPPH 7ZR REVHUYHUV PHDVXUHG DOO LPDJHV WZLFH GLJLWDOO\ DQG WZLFH PDQXDOO\ 2QH REVHUYHU PHDVXUHG WKH LPDJHV WZLFH GLJLWDOO\ DQG RQFH PDQXDOO\,QWRWDODOOLPDJHVZHUHPHDVXUHGWLPHV 8.1.4 Paper IV $OOSDUWLFLSDQWVLQWKHIRXUWKVWXG\ZHUHERUQGXULQJDQGLQFOXGHGLQWKH +LS3URMHFWZLWKTXHVWLRQQDLUHVFOLQLFDOH[DPLQDWLRQDQGWZRUDGLRJUDSKVQ 7KH UDGLRJUDSKV ZHUH PHDVXUHG E\ RQH RI WKUHH REVHUYHUV XVLQJ WKH GLJLWDO PHDVXUHPHQWSURJUDPPH$GXOWB''+5DGLRJUDSKLFPHDVXUHPHQWVUHOHYDQWIRUKLS G\VSODVLDDWVNHOHWDOPDWXULW\ZHUHXVHGWRFODVVLI\WKHUDGLRJUDSKVDQGWRJURXSWKH KLSV LQWR HLWKHU ³QRUPDO´ ³ERUGHUOLQH´ RU ³G\VSODVWLF´ 7KH UDGLRJUDSKLF ILQGLQJV ZHUHUHODWHGWRERG\PDVVLQGH[%0,UDQJHRIPRWLRQRIWKHKLSV%HLJKWRQVFRUH (4'VFRUHDQG:20$&VFRUH 8.2 OUTCOME MEASURES 8.2.1 Radiographic parameters associated with hip dysplasia at skeletal maturity 6HYHUDO GLIIHUHQW UDGLRJUDSKLF PHDVXUHPHQWV KDYH EHHQ SURSRVHG WR GHILQH KLS G\VSODVLD EXW WKHUH LV QR FRQVHQVXV RQ ZKDW PDUNHUV ZLWK FRUUHVSRQGLQJ FXWRII YDOXHVWRXVH7KHPDUNHUVFDQEHJURXSHGLQWRWKUHHGLIIHUHQWFDWHJRULHVDFFRUGLQJWR ZKDWWKH\DUHGHVLJQHGWRPHDVXUH Acetabular anatomy )LJXUH 6KDUS¶V DFHWDEXODU DQJOH 7KLV LV GHILQHG DV WKH DQJOH EHWZHHQ WKH KRUL]RQWDO WHDUGURSOLQHDQGDOLQHWKURXJKWKHLQIHULRUWHDUGURSSRLQWDQGWKHODWHUDOULPRIWKH DFHWDEXOXP6\QRQ\PVXVHGLQWKHOLWHUDWXUHDUH³WKHDFHWDEXODUDQJOH´DQG³DQJOH RILQFOLQDWLRQ´ AA ADR = (A/B)*1000 A B Sharp’s angle Teardrop line Figure 18 The acetabular anatomy is assessed by Sharp's angle, the acetabular roof angle of Tönnis (AA) and the acetabular depth-width ratio (ADR). 7KHDFHWDEXODUURRIDQJOHRI7|QQLV$$7KLVLVWKHDQJOHEHWZHHQDOLQHSDUDOOHO WRWKHKRUL]RQWDOWHDUGURSOLQHDQGDOLQHGUDZQWKURXJKWKHPHGLDOSRLQWRIWKHVRXUFLO DQG WKH ODWHUDO DFHWDEXODU ULP ,Q WKH OLWHUDWXUH V\QRQ\PRXV QDPHV DUH ³KRUL]RQWDO WRLW H[WHUQH´ +7( 7RLW )UHQFK IRU URRI DFHWDEXODU URRI REOLTXLW\ $52DQGDFHWDEXODULQGH[$, 7KH DFHWDEXODU GHSWKZLGWK UDWLR $'5 7KH UDWLR RI WKH GLVWDQFH EHWZHHQ WKH LQIHULRUWHDUGURSSRLQWDQGWKHODWHUDODFHWDEXODUULPDQGWKHGHSWKRIWKHDFHWDEXOXP PXOWLSOLHGE\ Position of the femoral head relative to the acetabular cavity )LJXUH :LEHUJ¶V &HQWUH(GJH &( DQJOH 7KLV LV GHILQHG DV D OLQH WKURXJK WKH FHQWUH RI WKH IHPRUDO KHDG SHUSHQGLFXODU WR WKH KRUL]RQWDO WHDUGURS OLQH DQG D OLQH UXQQLQJ IURPWKHFHQWUHRIWKHIHPRUDOKHDGWKURXJKWKHODWHUDODFHWDEXODUHGJH 2JDWD¶VDQJOH7KLVLVDPRGLILFDWLRQRI:LEHUJ¶V&(DQJOHGLIIHULQJRQO\VOLJKWO\ IURP WKLV DV 2JDWD¶V DQJOH XVHV WKH ODWHUDO HGJH RI WKH VRXUFLO LQVWHDG RI WKH ODWHUDO DFHWDEXODUHGJH )HPRUDO KHDG H[WUXVLRQ LQGH[ )+(, 7KLV LV GHILQHG DV WKH SHUFHQWDJH RI WKH IHPRUDO KHDG O\LQJ PHGLDO WR WKH ODWHUDO DFHWDEXODU HGJH 6RPH DXWKRUV DOVR GHVFULEHWKHRSSRVLWHLHWKHSHUFHQWDJHRIWKHIHPRUDOKHDGO\LQJODWHUDOO\WRWKH Ogata’s angle A Wiberg’s angle B FHEI = (A/B)*100 Teardrop line Figure 19 The position of the femoral head relative to the acetabular cavity is defined using Wiberg's Centre-Edge (CE) angle, a modification of this (Ogata's angle) and the femoral head extrusion index FHEI . 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QRUPDO LQFUHDVHG RU GHFUHDVHG DQJOH DQG 25-88 18-19 40-75 Urograms General population Hip pain and/or hip motion limitation >45 95 radiographs 3 observers 51 hips 2 observers 30 radiographs 2 observers 51 radiographs 2 observers 39 radiographs 2 observers 36 radiographs 3 observers 30 radiographs 0.61 0.45 0.63 0.73-0-89 25-88 18-40 “Normal” population 18-19 40-75 General population Hip pain and/or hip motion limitation 0.83 0.89 0.63 0.83 0.86 0.84 0.75 0.70-0.79 0.90 18-57 0.86-0.89 AA 16-54 0.70-0.82 Sharp’s angle 18-89 N/A Age group (years) 16-32 0.80-0.95 0.84-0.90 0.78-0.92 0.50-0.92 Normal hips of patients with CLP in the contralateral hip Routine control, no hip/lumbar pain Patients from orthopaedic outpatient clinic Femoroacetabular impingement, mild hip dysplasia urograms Unilateral hip dysplasia 100 radiographs 3 observers 39-136 hips Nelitz et al. 1999 246 Wiig et al. 2002 148 Lequesne et al. 2004 215 Tannast et al. 2008 155 Mast et al. 2011 145 Lee et al. 2011 210 Stubbs et al. 2011 Engesæter et al.70 2012 38 Bouttier et al. 2012 166 Diagnosis N radiographs N observers Authors Year 0.83-0.89 0.91-0.93 0.78-0.90 0.72-0.80 0.81-0.92 0.77 0.84 0.65-0.69 ADR 0.84 0.91 0.82 0.67 0.70-0.83 0.73 0.92 0.90 0.25-0.72 0.88-0.92 Wiberg’s CE angle 0.84-0.97 0.94-0.96 0.77-0.94 0.69-0.84 0.76 0.86-0.97 18-57 0.97-0.98 0.93-0.98 0.85-0.96 0.88-0.92 Wiberg’s CE angle 0.90 0.88-0.95 0.65-0.69 ADR 17-90 0.55-0.84 0.74-0.89 16-54 0.91-0.94 0.86-0.89 AA 0.90-0.97 0.42-0.85 0.70-0.82 Sharp’s angle 3-36 months 18-89 Age group (years) 16-32 Table 6 Inter-observer variation reported in the literature 36 radiographs 3 observers 95 radiographs 3 observers 51 hips 2 observers Routine control, no hip/lumbar pain Patients from orthopaedic outpatient clinic Hip contusion or routine health check Femoroacetabular impingement, mild hip dysplasia Normal or osteoarthritis Hip dysplasia Unilateral hip dysplasia 100 radiographs 3 observers 30 radiographs 2 observers 30 radiographs 2 observers 51 radiographs 2 observers 50 radiorgaphs 1 observer 39 radiographs 2 observers 25 radiographs 2 observers Nelitz et al. 1999 Tan et al.214 2001 148 Lequesne et al. 2004 215 Tannast et al. 2008 111 Im et al. 2009 155 Mast et al. 2010 McWilliams et al.157 2010 145 Lee et al. 2011 70 Engesæter et al. 2011 38 Bouttier et al 2012 166 Diagnosis N radiographs N observers Authors Year Table 5 Intra-observer variation reported in the literature 0.82 0.84 0.90 0.91 0.65-0.90 0.73-0.87 FHEI 0.79-0.95 0.88-0.93 0.80-0.96 0.94-0.97 0.73-0.87 FHEI 0.98 0.95 0.78-0.92 ATD 0.95-0.99 0.93-0.97 ATD 0.55-0.65 0.49-0.69 0.78 JSW 0.57-0.81 0.37-0.80 0.98 0.90-0.92 0.77-0.90 JSW Manual technique Digital technique Manual technique Digital technique .DSSD YDOXHV ZHUH FDOFXODWHG LQWUDREVHUYHU UHOLDELOLW\ . 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Danish -left 2007 Saudi 2005 Turkish 2003 Malawian Japanese 2000 French Japanese 1998 British 1998 Korean Caucasian - right 1997 Caucasian - left 1996 Indian 1996 Nigerian 1995 British 1995 Chinese 1991 British 1973 Hong Kong Chinese pelvic pelvic pelvic pelvic pyelogram urogram urogram pelvic urogram Type of radiograph 2604 2072 2072 488 315 3859 3859 208 184 180 1538 783 395 2993 1182 251 247 262 126 393 1993 18-19 18-60 20-64 22-93 40-88 55-97 N/A 20-79 20-79 60-79 60-75 22-88 65+ 18-73 60-75 60-75 60-75 60-75 60-74 (years) hips 74 Age N 3.0 2.0 3.6 21 3.5* 3.5* 0.0 0.0 2.2 0 F 1.6 1.1 2.3 14 3.6* 3.1* 0.0 2.3 1.3 0 1.1 1.0 M CE<20Û * The lateral margin of the subcondral sclerotic sourcil was used as the lateral point of reference (Ogata’s point) Engesæter et al. Aly et al. 9 Johnsen et al. 255 120 159 160 Jacobsen et al. Moussa et al. Goker et al. Msamati et al. Inoue et al. Yoshimura et al. Han et al. Lane et al. Mandal et al. Ali-Gombe et al. Smith et al. Lau et al. 140 Croft et al. 6 105 Hoaglund et al. Year Population group 16 14 5.5 24 7.4 13 12 5.6 19 4.0 2.4 4.0 3.9 3.8 F 12 10 4.5 17 10 12 5.1 1.8 16 4.0 3.8 2.4 4.5 3.6 5 M CE<25Û 7.9 7.6 8.4 7.7 F 8.7 8.1 10.7 9.8 M ADR<250 11 11 8.4 8.2 F 3.8 2.9 3.4 3.2 M Sharp>45Û 4.5 2.7 2.3 1.4 F 3.6 2.4 5.6 4.5 M FHEI<75% Authors Table 6 Occurrence in percent of adult hip dysplasia in the literature based on Wiberg’s centre-edge (CE) angle, acetabular depth-width ratio (ADR), Sharp’s angle and femoral head extrusion index (FHEI) for females (F) and males (M). 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SOURCES OF DATA $GHEDMR$23DWWHUQRIRVWHRDUWKULWLVLQD:HVW$IULFDQWHDFKLQJKRVSLWDOAnn Rheum Dis 1991;50-1:20-2. $JXV+%LFLPRJOX$2PHURJOX+7XPHU<+RZVKRXOGWKHDFHWDEXODUDQJOH RI6KDUSEHPHDVXUHGRQDSHOYLFUDGLRJUDSK"J Pediatr Orthop 2002;22-2:228-31. $KPDG0$;\SQLWRV)1*LDQQRXGLV390HDVXULQJKLSRXWFRPHVFRPPRQ VFDOHVDQGFKHFNOLVWVInjury 2011;42-3:259-64. $NWDV63HNLQGLO*(UFDQ63HNLQGLO<$FHWDEXODUG\VSODVLDLQQRUPDO 7XUNLVKDGXOWVBulletin 2000;59-3:158-62. $OELQDQD-0RUFXHQGH-$:HLQVWHLQ6/7KHWHDUGURSLQFRQJHQLWDO GLVORFDWLRQRIWKHKLSGLDJQRVHGODWH$TXDQWLWDWLYHVWXG\J Bone Joint Surg Am 1996;78-7:1048-55. $OL*RPEH$&URIW356LOPDQ$-2VWHRDUWKULWLVRIWKHKLSDQGDFHWDEXODU G\VSODVLDLQ1LJHULDQPHQJ Rheumatol 1996;23-3:512-5. $OWPDQ'*Practical statistics for medical research.&KDSPDQ+DOO $OWPDQ5'%ORFK'$%ROH**-U%UDQGW.'&RRNH'9*UHHQZDOG5$ +RFKEHUJ0&+RZHOO'6.DSODQ'.RRSPDQ:-HWDO'HYHORSPHQWRI FOLQLFDOFULWHULDIRURVWHRDUWKULWLVJ Rheumatol 1987;14 Spec No:3-6. $O\7$+LSPRUSKRORJLFPHDVXUHPHQWVLQDQ(J\SWLDQSRSXODWLRQOrthopedics 2011;34-4. $PHULFDQ$FDGHP\RI3HGLDWULFV&RPPLWWHHRQ4XDOLW\,PSURYHPHQW 6XEFRPPLWWHHRQ'HYHORSPHQWDO'\VSODVLDRIWKH+LS&OLQLFDOSUDFWLFHJXLGHOLQH HDUO\GHWHFWLRQRIGHYHORSPHQWDOG\VSODVLDRIWKHKLSPediatrics 2000;105-4 Pt 1:896-905. $QGD66YHQQLQJVHQ6*U¡QWYHGW7%HQXP33HOYLFLQFOLQDWLRQDQGVSDWLDO RULHQWDWLRQRIWKHDFHWDEXOXP$UDGLRJUDSKLFFRPSXWHGWRPRJUDSKLFDQGFOLQLFDO LQYHVWLJDWLRQActa Radiol 1990;31-4:389-94. $QGHUVVRQ-(1HRQDWDOKLSLQVWDELOLW\UHVXOWVDQGH[SHULHQFHVIURPWHQ\HDUVRI VFUHHQLQJZLWKWKHDQWHULRUG\QDPLFXOWUDVRXQGPHWKRGActa Paediatr 2002;918:926-9. $QGHUVVRQ-(9RJHO,8OGEMHUJ16HUXPEHWDHVWUDGLROLQQHZERUQDQG QHRQDWDOKLSLQVWDELOLW\J Pediatr Orthop 2002;22-1:88-91. $QGR0*RWRK(6LJQLILFDQFHRILQJXLQDOIROGVIRUGLDJQRVLVRIFRQJHQLWDO GLVORFDWLRQRIWKHKLSLQLQIDQWVDJHGWKUHHWRIRXUPRQWKVJournal of pediatric orthopedics 1990;10-3:331-4. $QGUpQ/3DOPpQ.6HDVRQDOYDULDWLRQRIELUWKGDWHVRILQIDQWVZLWKFRQJHQLWDO GLVORFDWLRQRIWKHKLSActa Orthop Scand 1963;33:127-31. $UPEXVWHU7**XHUUD--U5HVQLFN'*RHUJHQ7*)HLQJROG0/ 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APPENDICES $SSHQGL[ 5HJLVWUDWLRQ)RUP±0HGLFDO%LUWK5HJLVWU\RI1RUZD\ 1RUZHJLDQ $SSHQGL[ 5HJLVWUDWLRQ)RUP±0HGLFDO%LUWK5HJLVWU\RI1RUZD\ 1RUZHJLDQ $SSHQGL[ 5HSRUWLQJ)RUP±7KH1RUZHJLDQ$UWKURSODVW\5HJLVWHU 1RUZHJLDQ $SSHQGL[ ,QYLWDWLRQOHWWHUTXHVWLRQQDLUHDQGFRQVHQWIRUP±3DSHU,, $SSHQGL[ 5HJLVWUDWLRQIRUP±3DSHU,, $SSHQGL[ ,QYLWDWLRQOHWWHU±7KH+LS3URMHFW $SSHQGL[ &RQVHQWIRUP±7KH+LS3URMHFW $SSHQGL[ 4XHVWLRQQDLUH,±7KH+LS3URMHFW $SSHQGL[ 4XHVWLRQQDLUH,,±7KH+LS3URMHFW $SSHQGL[ &OLQLFDOH[DPLQDWLRQIRUP±7KH+LS3URMHFW Melding om avsluttet svangerskap etter 12. uke – Fødsel, dødfødsel, spontanabort Se utfyllingsinstruks for blanketten på baksiden Mors fulle navn og adresse A – Sivile opplysninger Institusjonsnr: Hjemme, planlagt Hjemme, ikke planlagt Mors sivilstatus Gift Ugift/enslig Samboer Skilt/separert/enke Slektskap mellom barnets foreldre? Nei Fars fulle navn Siste menstr. 1. blødn.dag Sikker B – Om svangerskap og mors helse Mors fødselsnr: Mors tidligere svangerskap/fødte Usikker Nei Spesielle forhold under svangerskapet: Intet spesielt Nei Kronisk hypertensjon Diabetes type 1 Tidligere sectio Reumatoid artritt Diabetes type 2 Res. urinveisinfeksjon Hjertesykom Annet, spesifiser i «B» Folat/Folsyre Blødning < 13 uke Hypertensjon alene Eklampsi Blødning 13–28 uke Preeklampsi lett Hb < 9.0 g/dl Blødning > 28 uke Preeklampsi alvorlig Hb > 13.5 g/dl Glukosuri Preeklampsi før 34. uke Trombose, beh. Nei Svangerskapsdiabetes HELLP syndrom Infeksjon, spes. i «B» Mors yrke Ja – spesifiser i «B» Røykte mor ved sv.sk. begynnelse? - ved sv.sk. avslutning? Samtykker ikke for røykeoppl. Nei Av og til Daglig Ant. sig. dagl.: Nei Av og til Nei Før sv.sk. I sv.sk. Multivitaminer Samtykker ikke for yrkesoppl. Mors yrke Ikke yrkesaktiv Yrkesaktiv deltid Ev. induksjonsmetode: Indikasjon for inngrep og/eller induksjon Prostaglandin Tverrleie Spontan Avvikende hodefødsel Indusert Amniotomi Annet, spesifiser i «C» Sectio Annet, spesifiser i «C» Oxytocin Vanlig fremhjelp Vakuumekstraktor Uttrekning Utført som elektiv sectio Episitomi Tang på etterk. hode Utført som akutt sectio Vannavg. 12–24 timer Placenta previa Blødn.> 1500 ml, transf. Truende intrauterin asfyksi Vannavg. > 24 timer Abruptio placentae Blødning 500–1500 ml Risvekkelse, stimulert Mekaniske misforhold Perinealruptur (grad 1-2) Eklampsi under fødsel Langsom fremgang Vanskelig skulderforløsning Sphincterruptur (gr. 3-4) Navlesnorfremfall Uterus atoni Lystgass Epidural Pudendal Paracervical blokk Spinal Infiltrasjon Petidin Koagler Sectio: Spesifikasjon av forhold ved fødselen/andre komplikasjoner Var sectio planlagt før fødsel? Nei C Annet: Annet: Fostervann Komplikasjoner hos mor etter fødsel Normal Utskrapning Normal Annet omslyng Normal Misfarget Intet spesielt Mor overflyttet Hinnerester Manuell uthenting Velamentøst feste Ekte knute Polyhydramnion Stinkende, infisert Feber > 38.5˚ Mor intensivbeh. Oligohydramnion Blodtilblandet Trombose Sepsis Ufullstendig Infarkter Marginalt feste Placentavekt Fødselsdato Navlesnorlengde: Karanomalier Klokken For flerfødsel: Pluralitet Enkeltfødsel Flerfødsel Nr. Kjønn Av totalt For dødfødte: Levendefødt Dødfødt/sp.abort Oppgi dødsårsak i «D» Gutt Barnets vekt: Pike Ved tvil spesifiser i «D» Ja Død før innkomst Ukjent dødstidspunkt Død etter innkomst D Usikkert kjønn Hodeomkrets: Levendefødt, død innen 24 timer Livet varte: Timer Indikasjon for overflytting: Apgar score: Total lengde: 1 min Eventuelt sete–issemål: 5 min Død senere (dato): Min. Medfødte misd. Prematur Perinatale infeksjoner Transit. tachypnoe Cerebral irritasjon Konjunktivitt beh. Fract. claviculae Medf. anemi (Hb < 13.5 g/dl) Resp. distress syndr. Cerebral depresjon Navle./hudinf. beh. Annen fraktur Systemisk antibiotika Hofteleddsdyspl. beh. m/pute Aspirasjonssyndrom Abstinens Perinat. inf. bakterielle Facialisparese Respiratorbeh. Intrakraniell blødning Neonatale kramper Perinat. inf. andre Plexusskade CPAP beh. Behandlingskoder: Spesifikasjon av skader, neonatale diagnoser og medfødte misdannelser – utfylles av lege Annet, spesifiser Icterus behandlet: Lysbehandlet Utskifting Årsak: AB0 uforlik. RH immunisering Fysiologisk Annen årsak Ja Kryss av hvis skjema er oppfølgingsskjema Utskrivningsdato Jordmor v/fødsel: Mor: Jordmor v/utskrivning: Protokollnr.: Klokken Respirasjonsproblem Hypoglyk. (< 2 mmol/l) Intet spesielt Nei Død under fødselen Dato: Neonatale diagn.: (Fylles ut av lege/pediater) Tegn til medfødte misdannelser: For dødfødte, oppgi også Overfl. til Overfl. barneavd. Nei Død før fødsel Annet, spesifiser Eklampsi post partum For dødfødte: Barnet var: D – Om barnet Ja Narkose Omslyng rundt hals Navlesnor Fostermisdannelser Annet, spesifiser i «C» Annen tang, hodeleie Ingen Komplikasjoner som beskrevet nedenfor Overtid Ingen Placenta: 23011. 07.06. Andvord Grafisk. Bransje: Yrkesaktiv heltid Ant. sig. dagl.: Fremhj. ved setefødsel: Anestesi/analgesi: B Legemidler i svangerskapet: Utskj. tang, hodeleie Ingen Ja, hvis bekreftet – spesifiser Annet, spesifiser i «B» Inngrep/tiltak Komplikasjoner Nei Spesifikasjon av forhold før eller under svangerskapet: Regelmessig kosttilskudd: Daglig Fødselstart: Sete Epilepsi Spontanaborter (under 12. uke) Patologiske funn ved prenatal diagnostikk? Ja, angi type: Allergi Skriftlig orientering gitt til mor IS-1002 Spontanabort/Dødfødte (12.–23. uke) Kronisk nyresykdom Forutsetter mors samtykke – se rettledning på baksiden Normal bakhode Dødfødte (24. uke og over) Astma Røyking og yrke Leie/presentasjon: Levendefødte Annen prenatal diagnostikk? UL Ja termin: Intet spesielt Pikenavn (etternavn): Annet sted Mors bokommune Fars fødselsdato Spesielle forhold før svangerskapet: Under transport Annet Hvis ja, hvorledes: Ja Ultralyd utført? C – Om fødselen Fødsel utenfor institusjon: Institusjonsnavn / Lege: Lege barsel/barneavd: Barn: Nasjonalt Register for Leddproteser Ortopedisk klinikk, Helse Bergen HF Haukeland universitetssjukehus Møllendalsbakken 11, 5021 BERGEN Tlf 55973742/55973743 HOFTEPROTESER F.nr. (11 sifre)..................................................................... Navn:.................................................................................. (Skriv tydelig ev. pasient klistrelapp – spesifiser sykehus.) Sykehus:............................................................................ ALLE TOTALPROTESER I HOFTELEDD REGISTRERES. Innsetting, skifting og fjerning av totalproteser i hofteledd, samt kantplastikk, bløtdelsrevisjon for infisert protese og hemiproteser på annen indikasjon enn fraktur/fraktursekvele. Hemiprotese for fraktur/fraktursekvele registreres på Hoftebruddskjema. TIDLIGERE OPERASJON I AKTUELLE HOFTE (ev. flere kryss) 0 Nei 1 Osteosyntese for fraktur i prox. femurende 2 Hemiprotese pga. fraktur 3 Osteotomi 4 Artrodese 5 Totalprotese(r) 6 Annen operasjon ………………………………………………….................... OPERASJONSDATO (dd.mm.åå) AKTUELLE OPERASJON (ett kryss) 1 Primæroperasjon (også hvis hemiprotese tidligere) 2 Reoperasjon (totalprotese tidligere) 3 Primær hemiprotese for annen indikasjon enn fraktur/fraktursekvele AKTUELLE SIDE (ett kryss) (Bilateral opr.= 2 skjema) 1 Høyre 2 Venstre ÅRSAK TIL AKTUELLE OPERASJON (KRYSS AV ENTEN I A ELLER B) A Primæroperasjon pga. (evt. flere kryss) 1 Idiopatisk coxartrose 2 Rheumatoid artritt 3 Sekvele etter frakt. colli. fem. 4 Sekv. dysplasi 5 Sekv. dysplasi med total luksasjon 6 Sekv. Perthes 7 Sekv. Epifysiolyse 8 Mb. Bechterew 9 Akutt fraktura colli femoris Annet ……….......….....……………………………………………………......... (f.eks caputnekrose, tidl. artrodese o.l) B Årsak til reoperasjon (evt. flere kryss) 1 Løs acetabularkomponent 10 Implantatfraktur femurdel 2 Løs femurkomponent 11 Implantatfraktur caput 3 Luksasjon 12 Implantatfraktur kopp 4 Dyp infeksjon 13 Implantatfraktur liner 5 Fraktur (i acetabulum) 14 Implantatfraktur annet: ............ 6 Fraktur (av femur) .................................................. 7 Smerter 8 Osteolyse i acetab. uten løsning 9 Osteolyse i femur uten løsning Annet ………………….......………………....………………………..….......... (f.eks Girdlestonesituasjon etter tidl. infisert protese) REOPERASJONSTYPE (ev. flere kryss) 1 Bytte av femurkomponent 2 Bytte av acetabularkomponent 3 Bytte av hele protesen 4 Fjernet protese og satt inn sementspacer 5 Fjernet sementspacer og satt inn ny protese 6 Fjernet protese (Girdlestone eller fjerning av sementspacer) Angi hvilke deler som ble fjernet …………....…………………………........... 7 Bytte av plastforing 8 Bytte av caput 9 Bløtdelsdebridement for infisert protese Andre operasjoner …………………………………………….……….............. TILGANG (ett kryss) 1 Fremre (Mellom sartorius og tensor) 3 Direkte lateral (Transgluteal) 2 Anterolateral (Mellom glut. medius og tensor) 4 Bakre (Bak gluteus medius) 5 Annen …………………………………………………………………….......... MINIINVASIV KIRURGI (MIS) 0 Nei LEIE 0 Sideleie 1 Rygg TROKANTEROSTEOTOMI 0 Nei 1 Ja 1 Ja BENTRANSPLANTASJON (ev. flere kryss) 0 Nei 1 Ja 2 Benpakking Acetabulum 0 Nei 1 Ja 2 Benpakking a.m. Ling/Gie Femur BENTAP VED REVISJON (Paprosky’s klassifikasjon se baksiden) 1I 2 IIA 3 IIB 4 IIC 5 IIIA Acetabulum 1I 2 II 3 IIIA 4 IIIB 5 IV Femur 6 IIIB PROTESEKOMPONENTER (Bruk klistrelapp på baksiden, eller spesifiser nøyaktig) Acetabulum Navn/Type ……..............………………………………………………………………............. ev. katalognummer ………........…………………………………………………........... Med hydroksylapatitt Uten hydroksylapatitt 1 Sement med antibiotika – Navn ……………………………………….................. 2 Sement uten antibiotika – Navn ……………………………………….................. 3 Usementert Femur Navn/Type ……………………………………………………………………............. ev. katalognummer …………………………………………………………........... Med hydroksylapatitt Uten hydroksylapatitt 1 Sement med antibiotika – Navn ……………………………………….................. 2 Sement uten antibiotika – Navn ……………………………………….................. 3 Usementert 4 Resurfacing Caput 1 Fastsittende caput 2 Separat caput - Navn/Type …………………………………………….................. ev. katalognummer …………………………………………………………............ Diameter ……………… SYSTEMISK ANTIBIOTIKA 0 Nei 1 Ja: 1 Profylakse 2 Behandling Navn Dosering Varighet i timer (døgn) Medikament 1 ..........................................……..….....…...............…. ......timer (......døgn) Medikament 2 ..........................................………..…..…................... ......timer (......døgn) Medikament 3 .................................................................……..…….. ......timer (......døgn) TROMBOSEPROFYLAKSE 0 Nei 1 Ja: Første dose 1 Preoperativt 2 Postoperativt Medikament 1 ............................. Dosering opr.dag……………………………………..... Dosering videre ………..........… Varighet …… døgn Medikament 2 ............................. Dosering …………..................... Varighet …… døgn Fast antikoagulasjon 0 Nei 1 Ja, type .......................................................................................................... FIBRINOLYSEHEMMER 0 Nei 1 Ja, medikament: …………………………………….. Dosering ……………...... OPERASJONSSTUE 1 ”Green house” 2 Operasjonsstue med laminær luftstrøm 3 Vanlig operasjonsstue OPERASJONSTID (hud til hud) …………………………min PEROPERATIV KOMPLIKASJON 0 Nei 1 Ja, hvilke(n) ............................................................................................................ ASA KLASSE (se baksiden for definisjon) 1 Frisk 2 Asymptomatisk tilstand som gir økt risiko 3 Symptomatisk sykdom 4 Livstruende sykdom 5 Moribund Lege ................................................................................................... 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GHOWDU6RPEHO¡QQLQJYLOGXInHQ03VSLOOHUHOOHUNURQHU 'RNXPHQWHUWHEXVVXWJLIWHULQQHQ6WRU%HUJHQYLORJVnEOLUHIXQGHUW 'XKDUInWWWLPH««NO«««««« 0DQJHDYGLQHMHYQDOGUHQGHYLORJVnEOLEHGWRPnGHOWDLGHQQHVWXGLHQ+YLVGHWHUHWVWHUNW ¡QVNHIUDGHJNDQYLSU¡YHnRUGQHGHWVOLNDWIOHUHYHQQHUNDQNRPPHVDPPHQ)RUnHQGUH GHQWLPHQGXKDUInWWWDUGXNRQWDNWPHGRVVSnWHOHIRQHOOHUHOOHU WUXGHJXQGHUVHQOHKPDQQ#KHOVHEHUJHQQR Besøksadresse: Haukeland Universitetssykehus, Jonas Liesvei 65, Postadresse: Helse Bergen HF, Postboks 1, 5021 Bergen Telefon 55 97 50 00 – Innvalg 55 97 28 90 – Telefaks 55 97 49 34 E-post: [email protected] Foretaksnr. NO 983974724 mva. 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Kryss av i rubrikkene under på det som er aktuelt. Leveres med samtykkeerklæringen. Ingen problemer Medfødt hofteleddsdysplasi Serøs coxitt (ikke-bakteriell betennelse i hofteleddet) Septisk artritt i hofteledd (bakteriell betennelse i hofteleddet) Calvé Legg Perthes` sykdom Epifysiolyse Brudd Leddgikt (Reumatoid artritt) Annet (Spesifiser:……………………………………………………………….) Vet ikke Har oppsøkt lege / Legevakt pga. problemer med hofte. Spesifiser:…………………. Har du noen sykdom som har vart over 3 måneder? Hvilken:…………………………. Hofteplager i nærmeste familie Har du søsken som har medfødt hoftelidelse og har vært behandlet med pute? Ja Nei Vet ikke Hvis ”ja”, antall: ( eks. 1 bror 2 søstre ) ......bror/brødre …...søster/søstre ……halvbror/halvbrødre …..halvsøster/halvsøstre Ja Nei Vet ikke Ja Nei Vet ikke Har du foreldre som har hatt medfødt hoftelidelse? Hvis ”ja”, hvem: mor far Har foreldrene dine plager med hoftene i dag? Hvis ”ja”, hvem: Mors høyde………cm mor far Fars høyde………cm Besøksadresse: Haukeland Universitetssykehus, Jonas Liesvei 65, Postadresse: Helse Bergen HF, Postboks 1, 5021 Bergen Telefon 55 97 50 00 – Innvalg 55 97 28 90 – Telefaks 55 97 49 34 E-post: [email protected] Foretaksnr. NO 983974724 mva. Internett: www.helse-bergen.no +2)7( HOFTE 89 Haukeland Universitetssykehus Mange takk for at du tar deg tid til å være med på Hoftestudien. Skjema brukes også for undersøkelse av helsetilstanden til eldre og alvorlig syke personer. Noen av spørsmålene kan derfor virke lite relevante for deg om du er helt frisk. Likevel ber vi deg lese gjennom hele skjema, og svare på alle spørsmålene. Der er totalt 43 spørsmål. 1. Deltakernummer:…………………. 2. Navn: …………………………………………………… 3. Fødselsnummer: |__|__| |__|__| |__|__| |__|__|__|__|__| 4. Yrke skoleelev annet (Spesifiser:…………………………….) 5. Har du noen gang hatt plager fra høyre hofte (varighet over 1 måner)? Ja Nei Hvis ”JA”, spesifiser…………………………………………. 6. Har du hatt plager fra høyre hofte siste 3 måneder? Ja Nei Hvis ”JA”, spesifiser…………………………………………. 7. Har du noen gang hatt plager fra venstre hofte (varighet over 1 måner)? Ja Nei Hvis ”JA”, spesifiser…………………………………………. 8. Har du hatt plager fra venstre hofte siste 3 måneder? Ja Nei Hvis ”JA”, spesifiser…………………………………………. 9. Hvor ofte har du vondt i nakken? omtrent hver dag mer enn 1 gang pr uke omtrent hver uke omtrent hver måned sjelden eller aldri Besøksadresse: Haukeland Universitetssykehus, Jonas Liesvei 65, Postadresse: Helse Bergen HF, Postboks 1, 5021 Bergen Telefon 55 97 50 00 – Innvalg 55 97 28 90 – Telefaks 55 97 49 34 E-post: [email protected] Foretaksnr. NO 983974724 mva. Internett: www.helse-bergen.no 2 10. Hvor ofte har du vondt i ryggen? omtrent hver dag mer enn 1 gang pr uke omtrent hver uke omtrent hver måned sjelden eller aldri 11. Har du problemer som du relaterer til hoften, som gjør at du har vansker med å gå? Ja Nei Hvis ”JA”, spesifiser…………………………………………. 12. Er det andre årsaker enn hofteplager som gjør at du har vansker med å gå? (For eksempel smerter fra andre ledd, ryggsmerter, hjerte-karsykdom eller andre sykdommer som påvirker gangevnen din) Ja Nei Hvis ”JA”, spesifiser……………………………………… 13. Utenom skoletid: Hvor mange GANGER i uken driver du med idrett/mosjon slik at du blir andpusten og/eller svett? hver dag 4-6 ganger i uken 2-3 ganger i uken 1 gang i uken 1 gang i måneden mindre enn 1 gang i måneden aldri 14. Utenom skoletid: Hvor mange TIMER i uken driver du med idrett/mosjon slik at du blir andpusten og/eller svett? ingen ½ time 1 time 2-3 timer 4-6 timer 7 timer eller mer 3 SMERTE- Tenk på smerten du opplevde I HOFTEN i løpet av de siste 48 timer. 15. Hvor mye smerter har du når du går på flatt underlag? ingen litt moderat stor svært stor 16. Hvor mye smerte har du når du går opp og ned trapper? ingen litt moderat stor svært stor 17. Hvor mye smerte har du om natten når du ligger i sengen? ingen litt moderat stor svært stor 18. Hvor mye smerter har du når du sitter eller ligger? ingen litt moderat stor svært stor 19. Hvor mye smerter har du når du står oppreist ingen litt moderat stor svært stor STIVHET- Tenk på stivheten du har opplevd i HOFTEN i løpet av de siste 48 timer 20. Hvor alvorlig er stivheten i hoften din med en gang du våkner om morgenen? ingen litt moderat kraftig svært kraftig 21. Hvor alvorlig er stivheten i hoften din etter at du sitter ligger eller hviler senere på dagen? ingen litt moderat kraftig svært kraftig FUNKSJON- Tenk på hvor vanskelig det har vært å utføre følgende daglige fysiske aktiviteter i løpet av de siste 48 timene, som følge av SMERTE I HOFTEN. Med dette mener vi din bevegelsesevne og evne til å klare deg selv. SPØRSMÅL: Hvor vanskelig har det vært å........ 22. gå ned trapper? ingen litt moderat svært ekstremt moderat svært ekstremt litt moderat svært ekstremt litt moderat svært ekstremt svært ekstremt 23. gå opp trapper? ingen litt 24. reise deg fra sittende? ingen 25. stå oppreist? ingen 26. bøye deg ned mot gulvet? ingen litt moderat 4 27. gå på flatt underlag? ingen litt moderat svært ekstremt moderat svært ekstremt moderat svært ekstremt moderat svært ekstremt moderat svært ekstremt litt moderat svært ekstremt litt moderat svært ekstremt 28. komme deg inn/ut av en bil? ingen litt 29. gå på handletur? ingen litt 30. ta på strømper? ingen litt 31. stå opp fra sengen? ingen litt 32. ta av strømper? ingen 33. ligge i sengen? ingen 34. komme deg inn/ut av dusj/badekar? ingen litt moderat svært ekstremt litt moderat svært ekstremt moderat svært ekstremt litt moderat svært ekstremt litt moderat svært ekstremt 35. sitte? ingen 36. komme deg til toalettet? ingen litt 37. tungt husarbeid? ingen 38. lett husarbeid? ingen 5 I de neste 5 spørsmålene (EQ-5D-spørsmålene (http://www.euroqol.org) ønsker vi å vite hvordan livssituasjonen din er: 39. Hvordan opplever du gangevnen din? 1 Jeg har ingen problemer med å gå omkring 2 Jeg har litt problemer med å gå omkring 3 Jeg er sengeliggende 40. Hvordan klarer du personlig stell? 1 Jeg har ingen problemer med personlig stell 2 Jeg har litt problemer med å vaske meg eller kle meg 3 Jeg klarer ikke å vaske meg eller kle meg 41. Hvordan klarer du dine vanlige gjøremål (f.eks. arbeid, studier, husarbeid, familie- og fritidsaktiviteter)? 1 Jeg har ingen problemer med å utføre mine vanlige gjøremål 2 Jeg har litt problemer med å utføre mine vanlige gjøremål 3 Jeg er ute av stand til å utføre mine vanlige gjøremål 42. Smerter eller ubehag? 1 Jeg har verken smerte eller ubehag 2 Jeg har moderat smerte eller ubehag 3 Jeg har sterk smerte eller ubehag 43. Angst eller depresjon? 1 Jeg er verken engstelig eller deprimert 2 Jeg er noe engstelig eller deprimert 3 Jeg er svært engstelig eller deprimert Mange takk for at du tok deg tid til å svare på spørreskjema! Trude G. Lehmann Cand.med Lene B. Laborie Cand.med Karen Rosendahl Seksjonsoverlege, Professor dr. med Radiologisk avdeling Ingvild Øvstebø Engesæter Stud.med Lars Birger Engesæter Seksjonsoverlege, Professor dr. med Barneortopedisk avdeling +2)7( 1DYQHODSS GHOWDNHUQU«« .OLQLVNXQGHUV¡NHOVH 8VGDWR«««« +¡\GH««««FP 9HNW««««NJ 6WDWXV+¡\UH9HQVWUH )OHNVMRQ (NVWHQVMRQ $EGXNVMRQ $GGXNVMRQ ,QQDGURWDVMRQ 8WDGURWDVMRQ )RUNRUWQLQJ PP PP ,PSLQJHPHQW 0RELOLWHW+¡\UH9HQVWUH +\SHUHNVWHQVMRQLNQH!" /HJJHUWRPPHOQHGSnXQGHUDUP" !GRUVDOIOHNVMRQLILQJHUVJUXQQOHGG" 7DLJXOYHWPHGKnQGIODWHPHGVWUDNHNQ U +\EHUHNVWHQVMRQLDOEX!" Besøksadresse: Haukeland Universitetssykehus, Jonas Liesvei 65, Postadresse: Helse Bergen HF, Postboks 1, 5021 Bergen Telefon 55 97 50 00 – Innvalg 55 97 28 90 – Telefaks 55 97 49 34 E-post: [email protected] Foretaksnr. NO 983974724 mva. Internett: www.helse-bergen.no 6 16. PAPERS I-IV