TY Syllabus - Dr. Babasaheb Ambedkar Marathwada University
Transcription
TY Syllabus - Dr. Babasaheb Ambedkar Marathwada University
Dr. Babasaheb Ambedkar Marathwada University, Aurangabad UNIVERSITY DEPARTMENT OF CHEMICAL TECHNOLOGY (Faculty of Engineering & Technology) Syllabus of Third Year B. Tech. (Chemical) (Semester-V) Subject Code No.: CED-301 Title: Mass Transfer Operation Teaching Scheme: Class Test: 20 marks Theory: 4 hrs/week Examination (Duration): 3 hrs Tutorial: - Theory Examination (Marks): 80 Credits: 4 Course Objective : To teach students the basic principles of mass transfer and to apply these principles, aided by computational tools, to the design of equipment used in separation processes. Unit – I : (a) Introduction to Mass transfer operation (b) Diffusion: Fick's law of diffusion, Steady state molecular diffusion in fluids under stagnant and laminar flow conditions, Diffusion through variable cross-sectional area, Diffusion coefficient:measurement and prediction, Measurement of liquidphase diffusion coefficient, Multicomponent diffusion, Diffusivity in solids and its applications (c) Mass transfer coefficients: Introduction to mass transfer coefficient, Equimolar counter-diffusion of A and B, Correlation for convective mass transfer coefficient, Correlation of mass transfer coefficients for single cylinder (d) Theories of mass transfer: Penetration theory, Surface Renewal Theory, Boundary Layer Theory, Interphase mass transfer theory, Overall mass transfer coefficients (e) Multistage equilibrium processes Unit – II : (a) Introduction to distillation (b) Vapor-liquid equilibrium Distillation columns and their process calculations, Continuous distillation columns, Analysis of binary distillation in trayed towers: McCabe-Thele Method, Determination of the stripping section operating line (SOL), (a) Analysis of binary distillation by Ponchon-Savarit Method, Unit – III : (b) (c) (d) (e) (a) (b) (c) Unit –IV : (d) (e) (a) (b) (c) Unit – V : (a) (b) (c) (d) Unit - VI : Stepwise procedure to determine the number of theoretical trays, Plate column: types of plates, hydraulic design Packed column: types of packing, flooding, NTU, HTU Batch distillation Introduction to Multicomponent Distillation Introduction to absorption, Design of packed tower, Design of packed tower based on overall mass transfer coefficient, packing, random and structured, flooding Counter-current multi-stage absorption (Tray absorber), Continuous contact equipment, Absorption with chemical reaction, Absorption accompanied by irreversible reactions Humidification and air conditioning: Basic concepts, Adiabatic saturation temperature, Humidification and dehumidification operations and design calculations, Mechanical Draft Towers: forced draft towers and induced draft towers, Design calculations of cooling tower, Key points in the design of cooling tower and Step-by-step design procedure of cooling tower, Evaporation loss of water in cooling tower Filtration and Centrifugation : Mechanism of filtration, basic equation, constant volume, constant pressure filtration, rate expressions with cake and filter cloth resistances, compressible and incompressible cakes, process design of filtration equipments and their performance evaluation, plate and frame, Nutsch, rotary, vacuum. Theory of centrifugal separation, design equations, centrifuge types, and performance evaluation. Leaching: Solid-liquid extraction: Solid - liquid equilibria, efficiency, performance evaluation Crystallization: supersaturation, growth rate and nucleation, types of crystaillzers, Crystallizer design (a) Evaporation: Theory of boiling and evaporation, nucleate and film boiling, B.P. rise, expressions for heat transfer coefficients, types of evaporators, multiple effect evaporations and steam economy. Performance evaluation of evaporators (b) Drying : Wet bulb, dry bulb and adiabatic saturation temperatures, humidity, drying mechanism, drying rate curves, estimation of drying time and process design of dryers e.g. spray, rotary, tunnel, tray, fluid bed and thin film, performance evaluation of dryers Text Books : 1. Unit Operations of Chemical Engineering, McCabe W. L., Smith J.C., Harriot P. 2. Mass Transfer Operations, Treybal R.E. 3. Mass Transfer Sherwood T.K. Dutta,B.K.,“Principles of Mass transfer and Separation Processes”.Prentice-Hall of India, New Delhi (2007). Subject Code No.: CED-302Title: Industrial Pollution Control Teaching Scheme: Class Test: 20 marks Theory: 3 hrs/week Examination (Duration): 3 hrs Tutorial: - Theory Examination (Marks): 80 Credits: 3 Course Objective Unit – I Unit – II Unit – III Unit –IV Unit – V Unit - VI Text Books : The subject addresses various issues like air, water and soil pollution. It focuses on characterization, analysis of different pollutants. It also covers impact of some industries on environment. The main objective of the subject is to introduce students to various industrial pollution control techniques. : (f) Introduction to Industrial Pollution control (g) Air pollution, Classification and sources of various air pollutants, Pathological effect of various air pollutant : (c) Standard for air (d) Air meteorology, Primary and secondary meteorological parameters, Concept of temperature inversion, Plume behaviour : (f) Air sampling and analysis (g) Control of air pollution, Techniques used for air pollution control: Adsorption, Absorption, Equipments for preventing air pollution : (d) Primary, secondary and tertiary characterization of water (e) Standard for water : (e) Primary treatment techniques: Screening, Grit removal, Neutralization, Equalization, Sedimentation, Flocculation (f) Secondary treatment techniques: Trickling filter, aerobic lagoon, anaerobic lagoon, activated sludge process, rotating disc contactor (g) Tertiary treatment techniques: hardness removal, color and odor removal, membrane separation (h) Disinfection of water : (c) Types of solid waste, Solid waste management, Composting, Land filling, Incineration (d) Layout of waste water treatment plant, layout of domestic drinking water plant, Sources of pollutant and prevention of pollution in following industries: Dairy, Canning, Sugar, Distillery, Beverage, Tannery, Textile, Pharma, Paper and pulp, petro chemical industry : 4. Pollution control in process industries,S.P.Mahajan,McGraw Hill. 5. Wastewater treatment, M.Narayanrao and A.K.Dutta,IBH 6. 7. 8. 9. Publication Delhi Waste water engineering,Metcalf and Eddy,tataMcGraw Hill Water Supply Engineering Volume-I,S.K.Garg,Khanna Publishers Environment pollution control engineering ,C.S.Rao,New age International Publication Handbook of air pollution prevention and control,NicholasP.Chemisinoff Subject Code No.: FTD-303 Title: Food Packaging Technology Teaching Scheme: Class Test: 20 marks Theory: 3 hrs/week Examination (Duration): 3 hrs Tutorial: - Theory Examination (Marks): 80 Credits: 3 Course Objective Unit – I Unit – II Unit – III Unit –IV Unit – V Unit - VI Text Books : The main objective of this subject is to impart knowledge and skills related to different packaging materials and food products packaging : Introduction to packaging. Packaging operation, package-functions and design. Principle and requirements of packaging. Different hazards acting on packages Deteriorative changes in foodstuff, shelf life of packaged foodstuff, methods to extend shelf-life. : Manufacturing process, important properties and uses of packaging materials like, wooden boxes, glass, metal container, Al – Containers, paper, corrugated and fiber board’s : Flexible packaging materials: LDPE, LLDPE, HDPE, HMHDPE, PP, PC, PVC, PVDC, PVOH, PET, Nylon, etc.. Their properties and Important uses. Laminates : Different type and importance : Evaluation of packaging material. Retortable pouches, biodegradable and edibles packaging materials and films. Aseptic packaging and active packaging. Shrink packaging and Bar coding. : Packaging Tests : WVTR, OTR/GTR, Bursting strength, tensile strength, tearing test, drop test, pumpture test, impact test etc… Packaging low and regulations : Food product characteristics and package requirements. Selection of materials, forms machinery and methods for fresh product (fruits and vegetable), eggs, meat, fish and marine products, snacks, confections, milk and milk products, cereals and bakery products. : 1. Painy, F.A. and Painy, H.Y. 1983. A Handbook of Food Packaging. Leonard Hill,Glasgow, UK. 2. Scicharow, S. and Griffin, R.C. 1970. Food Packaging. AVI, Westport. 3. Gordon L. Robertson 1993. Food Packaging: Principles and Practice. Marcel Dekker. Subject Code No.: PTD-303 Teaching Scheme: SubjectTitle: Pharmaceutical Analysis-I Class Test: 20 marks Theory: 3 hrs/week Theory Examination (Duration): 3 hrs Tutorial: Theory Examination (Marks): 80 Credits: 3 Course Objectives : To understand basic concepts of different titrations used in Pharmaceutical Analysis. Unit-I : Definition, scope of Pharmaceutical Analysis. Introduction to analytical Techniques- Volumetric, gravimetric, gasometric and instrumental techniques. Study of contents of official monographs in detail (Monographs of aspirin & calcium gluconate powder to be studied). Unit-II : Standardization- Specifications for quality control, manufacturing variations, storage & dating of products, conditions of use, dosage forms. Significance of physical constants- melting point, boiling point, optical rotation, refractive index, specific gravity, light absorption, infrared absorption, viscosity, jelly strength, swelling power, polymorphism, particle size. Unit-III : Theoretical basis of quantitative analysis – Concept of solute, solvent, solution, molarity, molality, normality, and formality, equivalent weight calculations in reactions mentioned below, parts per thousand/million/billion, expression in %, primary, secondary standards and problems related to it. Unit-IV : Aqueous acid – base titration: Law of mass action and its applications (Problems related to it), acidimetry and alkalimetry with their standardization, end point detection, neutralization indicators (structures to be included).Assays of aspirin, ibuprofen, boric acid, benzoic acid, borax, Zinc oxide, milk of magnesia, lithium carbonate, benzyl nenzoate, tolbutamide, probenecid. Unit-V : Non-aqueous titration: Principle, theory, types of non-aqueous solvents, titration of alkali metals salt of organic acids, titration of amines and amine salts of organic acids, titration of halogen acid salt of bases & titration of acidic substances. Assays of codeine phosphate, ephedrine HCL, ethosuximide, phenobarbitone, Pilocarpine nitrate. Methods for determination of water, Karl Fischer titrimetry. Unit-VI : Complexometric titrations: Principle, theory, end point detection using pM indicators (catechol violet, erichrome black T, xylenol orange, murexide-chemical structures to be included), disodium edetate titrations and standardization, masking &demasking agents. Oxidation-reduction titrations: Principle & theory, redox indiators,Argentimetric titrations: Principle and theory, Mhor’s method, volhard’s method, Fajan’s method, indicators used in argentimetry.Gravimetric analysis: Unit operations, calculations and problems related to it. Text Books : a) b) c) d) e) f) g) h) i) j) Beckett A.H, Stenlake J.B., “Practical Pharmaceutical Chemistry – Part One”, IV editon, CBS Publishers and Distributors, New Delhi. Jeffery G.H., Bessett J., Mendham J., Denney R.C., “Vogel’s Textbook of Quantitative Chemical Analysis”, V Editon, ELBS Publications, London. KarAshutosh, “Pharmaceutical Drug Analysis”’ II edition, New Age International Publisher, New Delhi. Sheorey S., Honrao M., “Pharmaceutical Analysis- I (Practical)”, I edition, Career publications, Nashik. Connors K.A., “A textbook of Pharmaceutical Analysis”, III edition, Orient Longman Publications. Mann & Saunders, “practical organic chemistry”, IV edition, Orient Longman Publications. Higuchi et al., “Pharmaceutical Analysis”, CBS Publishers, New Delhi Garratt D.C., “The Quantitative Analysis of Drugs”, II edition, Sunders, New York. Atherden L.M., “Bentley & Driver’s Textbook of Pharmaceutical Chemistry”, VIII edition, Oxford University Press, Mumbai. Pharmacopoeia of India, Vol. I & II Controller of Publications, Govt. of India, New Delhi. Subject Code No.: FTD-304 Teaching Scheme: Subject Title: Food Processing Technology- II (Milk & Milk Products Processing) Class Test: 20 marks Theory: 3 hrs/week Theory Examination (Duration): 3 hrs Tutorial: Theory Examination (Marks): 80 Credits: 3 Course Objectives : To get acquainted with the processing technology of milk and milk products Unit-I : Milk and colostrums,-Definition, composition of milk from different species, factors affecting composition, food and nutritive value, physicochemical properties of milk constituent, clean milk production, buying and collection of milk at milk plant and testing for quality. Unit-II : Special milks-sterilized milk, homogenized milk, soft curd milk, flavored milk, fermented milk, standardized milk, reconstituted/rehydrated milk, recombined milk, toned milk, double toned milk, condensed milk, dried milks. Unit-III : Cream-Introduction, definition, classification, composition, physicochemical properties, production of cream, judging and grading of cream, uses. Butter-introduction, definition,classification, composition, physicochemical properties, production of butter, packaging and storage, judging and grading of butter, uses. Unit-IV : Ice cream-introduction, definition, composition, role of different constituents on quality, manufacture of ice cream, packaging, judging and grading of ice cream, defects, uses. Unit-V : Fermented milk products-Cheese, introduction, definition, classifications, and manufacture of different cheeses, judging and grading, defects, uses. Yoghurt-introduction, definition, composition, method of manufacture, uses. Unit-VI : Indian dairy products-introduction, definition, flow diagram of manufacture from whole milk, kheer, khoa, rabri, kulfi, dahi, shrikhand, paneer, channa, ghee, lassi, peda, gulabjamun, rasogola. Byproducts of dairy industry and their utilization. Text Books : 1.Outlines of Dairy Technology-Sukumar De 2.Technology of Milk Processing-Khan Q A and Padmanabhan 3.Principles of Dairy Processing-Warner J N 4.The Fluid Milk Industry Henderson J L 5.Indian dairy Products-Rangappa K S and Acharya K L Subject Code No.: PTD-304Subject Title: Pharmacognosy Class Test: 20 marks Teaching Scheme: Theory: 3 hrs/week Theory Examination (Duration): 3 hrs Tutorial: Theory Examination (Marks): 80 Credits: 3 Course Objectives : To understand the basic concepts of natural obtaining drugs Unit-I : Definition, History, Scope and Development of Pharmacognosy, importance of taxonomy and chemotaxonomy in evolution of Pharmacognosy. Study of plant cell and tissue system in plant. Unit-II : Sources of crude drug: Biological, marine, Mineral and plant tissue culture as source of crude drug. Classification of crude drug: Alphabetical, Morphological, Taxonomical, chemotaxonomical, Chemical and Pharmacological classification of crude drug. Unit-III : Cultivation collection processing and storage of crude drug, factors influencing quality of crude drug, types of fertilizers, pest management and pest control, plant hormones and their application Unit-IV : Natural Mineral: sources, chemical constituents, adulterants and uses of: Talc, Bentonite, Kaolin, Asbestos, Kieselguhr, and Calamine. Biological sources, chemical constituents, adulterants and uses with method of preparation of Carbohydrates and derived products: agar, guar gum acacia, Honey, Isabgol, pectin, Starch, sterculia and Tragacanth. Natural pesticides: Tobacco, Pyrethrum, Neem Unit-V : Alternative various systems of medicine practiced in India viz: Ayurveda, Unani, Homeopathic and Siddha. The holistic concept of drug administration in traditional systems of medicine. Introduction to Ayurvedic preparations like Arishtas, Asvas, Gutikas, Tailas, Chumas, Lehyas and Bhasmas. Unit-VI : Studies of traditional drugs, common vernacular names, botanical sources, morphology, chemical nature of chief constituents, pharmacology, categories and common uses and marketed formulations of following indigenous drugs: Amla, Kantkari, Satavari, Tylophora, Bhilawa, Kalijiri, Bach, Rasna, Punamava, Chitrack, Apamarg, Gokhru, Shankhapushpi, Brahmi, Ashoka, Methi, Lahsun, Palash, Guggal, Gymnema, Shilajit, Nagarmotha, Neem, Manjistha, Gulvel, Pippali and Chirata. Text Books : Wallis T. E., Textbook of Pharmacognosy, CBS, Delhi Jean Bruneton., Pharmacognosy and Phytochemistry, Lavosier Publisher U.K. Wagner and Bladt, Plant Drug analysis, Springer U.K. V. E. Tylor, L. R. Brady and S. B. Robbers, Pharmacognosy, K.M. Varghese Co.Bombay. Indian Herbal Pharmacopoiea, K. M. Varghese Co.Bombay. Craker L., Herbs, Spices And Medicinal Plants, CBS Publishers V. V. Sivarajan, Introduction to the Principles of Plant Taxonomy, Syndicate of university of Cambridge O P. Sharma, Plant Taxonomy, Tata McGraw-Hill Education Trease and Evans, Pharmacognosy, W. B. Saunders, New York Subject Code No.: FTD-305Subject Title: Food Processing Technology-III (Cereals, Legumes and Oilseeds Processing) Teaching Scheme: Class Test: 20 marks Theory: 3 hrs/week Theory Examination (Duration): 3 hrs Tutorial: Theory Examination (Marks): 80 Credits: 3 Course Objectives : To get acquainted with the processing technology of cereals, legumes and oilseeds. Unit-I : Present status and future prospects of cereals, legumes and oilseeds in India. Production, morphology, physicochemical properties, classification and types, composition and nutritive value. Unit-II : Post harvest processing of cereals, legumes and oilseeds at home scale, cottage scale and commercial scale for drying, Parboiling of paddy, rice, corn sorghum, pearl millet processing, dal milling. Unit-III : Wheat types, classification, milling, flour types, uses for manufacture of cakes, breads, biscuits, macaroni products. Unit-IV : Soaking, cooking, sprouting, fermentation of grains and manufacture of processed products. Oil extraction from oilseeds by different methods, oil refining, oilseeds and legumes meals and manufacture of different products. Unit-V : Manufacture of different products from cereals, legumes and oilseeds flours such as bhakri, roti, traditional products. Unit-VI : Byproducts of wheat milling industry, rice milling industry, oil extraction industry, legume milling industry and their utilization. Text Books : 1. Technology of Cereals- Kent 2.Post Harvest Technology of Cereals, legumes and OilseedsChakrawarthy 3.Post harvest Biotechnology of Legumes-Salunkhe DK and Kadak SS 4.Post Harvest Biotechnology of Oilseeds - Salunkhe DK and Kadak SS Subject Code No.: PTD-305Subject Title: Pharmaceutics-II Class Test: 20 marks Teaching Scheme: Theory: 3 hrs/week Theory Examination (Duration): 3 hrs Tutorial: Theory Examination (Marks): 80 Credits: 3 Course Objectives : To understand the basic concepts of formulation studies. Unit-I : Unit-II : Unit-III : Unit-IV : Unit-V : Unit-VI : Text Books : Pharmaceutical Plant, location, layout Plant location and lay out of an industry. Various factors affecting locational aspects of chemical and pharmaceutical plants. Layout of plant building and importance of flow sheet, difference between scientific process and technological process, layout of various departments, equipments, product lay out v/s process layout Dosage Form Necessities and Additives Antioxidants, preservatives, coloring agents, flavoring agents and diluting agents, emulsifying agents, suspending agents, ointment bases, solvents, and others Parenterals - product requiring sterile packaging Definition, types advantages and limitations, general formulation, vehicles, production, procedure, production facilities, controls, tests, selected IP injections, sterile powders, implants, emulsions, suspensions formulation of calcium gluconate injection. Suppositories (2-3 examples) Ideal requirements, bases, manufacturing procedure, evaluation methods, IP products Semisolids (Ointments, pastes, creams and jellies) Definitions, bases, general formulation, manufacturing procedure, evaluation methods, IP products. Pharmaceutical Aerosols Definition, propellants, general formulation, manufacturing and packaging methods, pharmaceutical applications. Impacts of propellants on environment. Metered aerosol Ophthalmic preparations Requirement, formulation, methods of preparation, containers, evaluation, IP products. Formulation, design and evaluations of novel drug delivery system. Radiopharmaceuticals. Govt. of India, Indian Pharmacopoeia, TheControllerof Publication B.P.Comission, British Pharmacopoeia, H.M.S.O.London LeonLachman, Leiberman, Pharmaceutical Dosage Form: Table, ChurchillLivingston LeonLachman, Leiberman, Pharmaceutical Dosage Form: DisperseSystem, ChurchillLivingston AlfonsaGennara, Remingtons,TheScience Practice of Pharmacy, Lippincott Bankar Gilbert, CristoferT.Rhods, Modern Pharmaceutics, MarcelDekker Subject Code No.: FTD-306Subject Title: Food Biotechnology Class Test: 10 marks Teaching Scheme: Theory: 2hrs/week Theory Examination (Duration): 2hrs Tutorial: Theory Examination (Marks): 40 Credits: 2 Course Objectives : To study the biotechnological aspects involved in food and its application for development of food in relation to food security. It is expected to learn genetics, molecular biology and basis for developments of genetically modified foods and their safety issues involved in food biotechnology Unit-I : Unit-II : Unit-III : Unit-IV : Unit-V : Unit-VI : Prospectus of Bio-Technology Molecular genetics i.e. fundamentals of molecular biology with special reference to chemistry and biology and DNA. (Primary secondary and tertiary) structures, Biological role of DNA in cell metabolism, Genetic recombination mechanisms and technique used for improvement in microbial strains, Applications of genetical control mechanism in industrial fermentation process, (Induction, manipulation and recombination), Recombinant-DNA technology (plasmids and cloning), Cell and tissue culture, Continuous cultures, Secondary metabolites synthesis, Application of Biotechnology in food (Food industries), pharmaceuticals and agriculture and Nutritional genomics. Application of biotechnology for food plant waste utilization, Biogas plant, Bio technology approach for the exploitation of food and industrially important microorganisms, Applications of genetical control mechanism in industrial fermentation process, (Induction, manipulation and recombination). Cell and tissue culture, Continuous cultures, Secondary metabolites synthesis. Text Books : 1Advances in Biotechnology Vol.1 Murayy Moo-Young (Scientific and Engineering principles) C.W. Gambell and C.Vezina 2Advances in Biotechnology Vol-II Murayy Moo-Young (Fuels, chemicals, foods and waste treatments) C.W. Gambell and C.Vezina 3Advances in Biotechnology Vol-III Muray Moo-Young (Fermentation Products) 4VIIth International Biotechnology Symposium (Feb 19-25 1984) held at New Delhi-Part-I 5VIIth International Biotechnology Symposium (Feb. 19-25 1984) Held at New Delhi Part-II. 6Microbial Technology-Vol-I Peppler and Perlman (Microbial Process) 7 Microbial Technology-Vol-I I Peppler and Perlman (Fermentation Technology) Subject Code No.: PTD-306Subject Title: Pharma Biotechnology Class Test: 10 marks Teaching Scheme: Theory: 2hrs/week Theory Examination (Duration): 2hrs Tutorial: Theory Examination (Marks): 40 Credits: 2 Course Objectives : To understand the basic concepts of pharmaceutical biotechnology Unit-I : Unit-II : Unit-III : Unit-IV : Unit-V : Unit-VI : Text Books : Plant Cell and Tissue Culture Structure of plant cell, DNA, Genes and chromosomes. Cell and tissue culture, Processes and applications Animal Cell Culture Introduction to animal cell culture, medium used in ATC. Use of FCS, primary culture, secondary culture, cell line. Cloning: concept and application with technical hurdles. Transgenic animals as source of food, organs and tissues, concept of xeno transplant Fermentation Technology and Industrial Microbiology Fermentation as biochemical process, types of fermentations. Recombinant DNA Technology BASIC CONCEPTS Biotechnology Derived Products Sources and upstream processing. Proteomics 1. Introduction 2. Genomic study, structural and functional genomes, human genome project. Formulation of Proteins and Peptides KeshavTreha, Biotechnology, New Age International publishers DaanJACrommelinandRobertDSindelar, PharmceuticalBiotechnololgy, Taylor And Francis MichelG.Grooves, Pharmaceutical Biotechnology, Taylor and FrancisgroupSecondedition Gary Walsh, Pharmaceutical Biotechnology Concepts AndApplication, Wiley InterscienceLtd. AluizioBoremFabricoR.S antos, DavidE., Understanding Biotechnology, Bowen,,Prentice& Hall Dr. Babasaheb Ambedkar Marathwada University, Aurangabad UNIVERSITY DEPARTMENT OF CHEMICAL TECHNOLOGY (Faculty of Engineering & Technology) Practical (V Sem) Subject Code No.: CED-321Subject Title: Lab. I- Mass Transfer Operation Teaching Scheme: Practical/Term Work: 4 hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objectives : List of Practicals : (Not Less than 10) List of Reference Books : List of Equipments /Instruments : To help students to apply the mass transfer theory in real list applications, understand separation processes and analysis methods 1. Diffusivity in gases (Stefan tube experiment) 2. Batch distillation 3. Plate Column Distillation 4. Packed Column Distillation 5. Absorption in packed column (physical) 6. Absorption in packed column (reactive) 7. Vacuum Drying (drying curve) 8. Filtration (medium and cake resistance) 9. Liquid-liquid equilibrium 10. Vapor-liquid equilibrium 11. Membrane filtration 12. Solubility data in crystallizer design 1. Unit Operations of Chemical Engineering, McCabe W. L., Smith J.C., Harriot P. 2. Mass Transfer Operations, Treybal R.E. Glass vessels, columns, burettes, pipettes, weighing balance, volumetric flasks, packing, temperature sensors, pressure gauge, vaccum pump, oven Subject Code No.: CED-322Subject Title: Lab. II- Industrial Pollution Control Teaching Scheme: Practical/Term Work: 3hrs/week Teachers Assessment: 25 marks Credits: 1 End Semester Examination: 25 marks Course Objectives : List of Practicals : (Not Less than 10) List of Reference Books : List of Equipments /Instruments : To study analysis of pollutants. 1. 2. 3. 4. 5. 6. 7. 8. To measure temperature and pH of given water sample. To measure temperature and pH of given soil sample. To determine moisture present in given soil sample. To determine total solid present in a given water sample. To determine settleable solid present in a given water sample. To determine hardness of a given water sample. To determine chloride content of given water sample. To determine dissolved oxygen of a given water sample by using Winkler’s method. 9. To determine biological oxygen demand of a given water sample. 10. To determine chemical oxygen demand of a given water sample. 11. To study various air sampling techniques 1. Waste water engineering,Metcalf and Eddy,tataMcGraw Hill 2. Water Supply Engineering Volume-I,S.K.Garg,Khanna Publishers Glass vessels, columns, burettes, pipettes, weighing balance, volumetric flasks, Imhoff cone, Jar test apparatus, Incubator,oven Subject Code No.: FTD-323Subject Title: Lab. III- Food Packaging Technology Teaching Scheme: Practical/Term Work: 3 hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objectives : List of Practicals : (Not Less than 10) List of Reference Books : List of Equipments /Instruments : The objective of this subject is to impart practical knowledge and skills related to different Food packaging 1. Identification of different types of packaging and packaging materials 2. Determination of tensile strength of given material 3. Determination of tearing strength of paper 4. Measurement of thickness of packaging materials 5. To perform grease-resistance test in plastic pouches 6. Determination of bursting strength of packaging material 7. Determination of water-vapour transmission rate 8. Demonstration of can-seaming operation 9. Testing of chemical resistance of packaging materials 10. Determination of drop test of food package 11. Estimation of shelf-life of packaged food stuff. 12. Cutout Examination of can 13. Preparation of label for different food products 14. Visit to relevant industries 15. Introducing the students with the latest trends in packaging consulting the websites and magzines 1. 2. 3. 4. 5. 6. WVTR and OTR analyzer Bursting strength analyzer Tearing strength analyzer Drop Tester Tensile strength tester Can reformer GSM analyzer Subject Code No.: PTD-323Subject Title: Lab. III- Pharmaceutical Analysis-I Teaching Scheme: Practical/Term Work: 3 hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objectives : To perform experimentation of titrimetric methods and its application in pharmaceutical analysis. List of Practicals (Not Less than 10) : 1. Methods of calibration: Pipettes, burettes, volumetric flask weighing balance, set of weights. 2. Determination of viscosity of solution of one of the following substances: gelatin or gum acacia or alcohol. 3. Acid-base titration: Preparation and standardization of 0.1 N HCl, 0.1 N NaOH, 0.1N H2SO4 one or more of the following drugs: aspirin or ibuprofen or acetaminophen. 4. Non-aqueous titration: Preparation and standardization of 0.1N perchloric acid. Assay of any one or more of the following drugs: Atenolol or Salbutamol sulphate or Mebendazole or Norfloxacin. 5. Precipitation titration: Preparation and standardization of 0.1N silver nitrate (Mohr’s method) - assay of saline or sodium chloride injection or powder or potassium chloride. 6. Permanganometric titration: Preparation and standardization of 0.1N potassium permanaganate. Assay of ferrous sulphate or hydrogen peroxide or potassium bromide. 7. Cerimetric Titration: Preparation and Standardization of 0.1M ceric ammonium sulphate. Assay of any one or more of the following drugs; ferrous sulphate or ferrous gluconate or acetaminophen. 8. Iodimetric titration: Preparation and Standardization of 0.1N iodine Assay of any one or more of the following drugs; ascorbic acid or dimercaprol or analgin tablets. 9. Iodometric titration: Preparation and standardization of 0.1N/0.1M sodium thiosulphate. Assay of any one or more of the following drugs; isoniazid or chlorinated lime or copper sulphate. 10. Potassium iodate titration: Preparation and standardization of 0.05M Potassium iodate and 1M sodium thoisulphate. Assay of any one or more of the following: potassium iodide or weak iodine solution or aqueous iodine solution. 11. Sodium nitrite titrations: Preparation and standardization of 0.1N sodium nitrite. Assay of any one or more of the following drugs; calcium carbonate or calcium gluconate or zinc oxide or calcium chloride or magnesium sulphate. 12. Complexometric titrations: Preparation and standardization of 0.01N sodium edetate. Assay of any one or more of the following drugs; calcium carbonate or calcium gluconate or zinc oxide or calcium chloride or magnesium sulphate. 13. Gravimetric analysis: Estimation of aluminium in alum or barium in barium chloride. List of Reference Books : List of Equipments /Instruments : a) Beckett. A.H., Stenlake J.B, “Practical Pharmaceutical Chemistry- Part one IV edition, CBS Publishers and Distributors, New Delhi. b) Jeffery G.H., Bassett J., Mendham J., Denney R.C., “Vogel’s Textbook of Quantitative Chemical Analysis”, V Edition, ELBS Publication, London. c) Sheorey S., Honrao M., “Pharmaceutical Analysis – I (Practical)”, I edition, Career Publications, Nashik. d) Mann & Saunders, “Practical Organic Chemistry”, IV edition, Orient Longman Publications. e) Pharmacopoeia of India, Vol. I & II, Controller of Publications, Govt. of India. New Delhi. Subject Code No.: FTD-324Subject Title: Lab. IV- Food Processing Technology-II Teaching Scheme: Practical/Term Work: 4hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objectives : List of Practicals : (Not Less than 10) 1. Sampling and analysis of milk-physicochemical properties, and tests for quality. 2. Clarification and separation of milk for cream. 3. Heat processing of milk-pasteurization by different methods. 4. Preparation of butter 5. Preparation of ghee 6. Preparation of ice-cream. 7. Preparation of dahi, shrikhand and lassi. 8. Preparation of khoa and khoa based sweets such as peda, gulabjamun. 9. Preparation of channa and channa based sweets such as rasogola. 10. Preparation of cheese and yoghurt. 11. Preparation of special milks such as toned milk, condensed milk, standardized milk, homogenized milk etc. 12. Visit to dairy plant List of Reference Books : List of Equipments /Instruments : 1.Outlines of Dairy Technology-Sukumar De 2.Technology of Milk Processing-Khan Q A and Padmanabhan 3.Principles of Dairy Processing-Warner J N 4.The Fluid Milk Industry Henderson J L 5.Indian dairy Products-Rangappa K S and Acharya K L Subject Code No.: PTD-324Subject Title: Lab. IV- Pharmacognosy Teaching Scheme: Practical/Term Work: 4hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objectives : To perform experimentation of natural obtained drugs List of Practicals : 1. Study of microscope 2. Techniques in microscopy, camera Lucida, details of mountants, clearing agents, micro-chemical reagents (Not Less than 10) 3. Identification of mineral drug by morphological characters and chemical characteristics-Agar, Tragacanth, Talc, Bentonite, Kaolin, Asbestos, Kieselguhr, Calamine. 4. Micrometers and measurement of microscopic characters (Size of starch grains/calcium oxalate crystal/fibers) 5. Study of morphological and microscopical characters of crude drugs of monocot and dicot stem, leaves roots, bark fruits and seeds. 6. Morphological study of plants under various families mentioned in theory (any two plant from each family) in local area. 7. Preparation of herbarium sheet and visit to Botany Department in Herbarium section 8. Field visit-Study of Medicinal plants List of Reference Books : 1. Practical Pharmacognosy by Khandelwal List of Equipments /Instruments : Microscope Light Microscope Subject Code No.: FTD-325Subject Title: Lab. V- Food Processing Technology-III Teaching Scheme: Practical/Term Work: 4hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objectives : To get acquainted with the processing technology of cereals, legumes and oilseeds. List of Practicals : 1. Morphology and physicochemical properties of cereals, legumes and oilseeds. (Not Less than 10) 2. Parboiling of paddy, rice milling and rice products, other cereal products. 3. Milling of wheat and wheat based products 5. Milling of sorghum, corn and millets. 6. Milling of legumes and legume based products 7. Extraction of oil from different methods. 8. Soaking, sprouting of legumes and cooking of dal. 9. Fermented products from legumes. 10. Production of breakfast cereals. 11. Production of traditional cereals, legumes and oilseed meals products List of Reference Books : 1. Technology of Cereals- Kent 2.Post Harvest Technology of Cereals, legumes and OilseedsChakrawarthy 3.Post harvest Biotechnology of Legumes-Salunkhe DK and Kadak SS 4.Post Harvest Biotechnology of Oilseeds - Salunkhe DK and Kadak SS List of Equipments : /Instruments Subject Code No.: PTD-325 Subject Title: Lab. V- Pharmaceutics-II Teaching Scheme: Practical/Term Work: 4 hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objectives : To perform experimentation of formulation. List of Practicals : 1. To prepare and evaluate the salicylic acid ointment (20 gm). (Not Less than 10) 2. To prepare aspirin tablet by dry granulation method. 3. To prepare and evaluate dispersible tablet 4. To prepare acetyl salicylic acid tablet by wet granulation. 5. To evaluate the marketed uncoated and coated tablet formulations. 6. Quality control of marketed formulations. 7. To study film coating. 8. To study sugar coating. 9. Demonstration of microencapsulation. 10. To study entry procedures in aseptic area. 11. Microbial count of aseptic area in filling zone. 12. To study pyrogen test for sterile product. 13. Preservative sorption of rubber closure. 14. To prepare and evaluate calcium gluconate injection I.P. 15. Preparation and evaluation of ascorbic acid injection I.P. 16. To prepare water for injection and study sealing of ampoules. 17. To prepare tablet by direct compression. 18. To prepare capsule formulations of any one drug. 19. To prepare basic ophthalmic eye drop. 20. To prepare glycerol gelatin suppository. 21. To prepare PEG suppository. 22. To design layout of Pharmaceutical plant for tablet, parenterals. 23. To prepare effervescent granules with iron. List of Reference Books : List of Equipments /Instruments : AlfonsaGennara, Remingtons,TheScience Practice of Pharmacy, Lippincott Bankar Gilbert, CristoferT.Rhods, Modern Pharmaceutics, MarcelDekker Tablet Punching Machine Capsule Feeling &Seeling machine Laminar Air Flow Tablet Coating Machine Dr. BabasahebAmbedkarMarathwada University, Aurangabad UNIVERSITY DEPARTMENT OF CHEMICAL TECHNOLOGY (Faculty of Engineering & Technology) Syllabus of Third Year B. Tech. (Chemical) (Semester-VI) Subject Code No.: CED-351Title: Instrumentation & Process Control Teaching Scheme: Class Test: 20 marks Theory: 3 hrs/week Examination (Duration): 3 hrs Tutorial: - 1hr/week Theory Examination (Marks): 80 Credits: 4 Course Objective Unit – I Unit – II Unit – III Unit –IV Unit – V Unit - VI Text Books : To get students acquainted with the instrumentation and process control system followed in the various foods, pharmaceutical and fine chemicals industries. : Measuring Instruments: Qualities of measurement, elements of instrument, static & dynamic characteristics, measurements of temperature and levels. : Measurement of pressure, vacuum, humidity & pH in process Industry in food, pharmaceutical and chemical industry. Flow measuring devices for incompressible and compressible fluids. : Methods for composition analysis. Principle and techniques of instruments for composition analysis in process industry, such as chromatography, spectroscopy, refractrometry . : Introduction to process control ,Set point, disturbance, closed and open loop control, feedback and feed forward.P,PD, PID, PI types of controllers and their Principles : Introduction to Simple system analysis : Laplace Transformation. Block diagrams, linearization. First and higher order System. : Frequency response, distributed parameter system, dead time. Feed back control, servo and regulator control. Time domain closed loop responses, closed loop frequency response. : 1) Industrial Instrumentation : Eckman, Wiley Eastern 2) Instrumental Methods of Chemical Analysis :Erwing, McGraw Hill. 3) Instrumentation & Process Measurements : W.Bottom, Orient Longman. 4) Industrial Control &Instrumentation :W.Bottom, Orient Longman. 5) Outlines of Chemical Instrumentation & Process Control : A. Suryanarayan, Khanna Pub., New Delhi. 6) Donald R. CoughaNowr : Process Systems Analysis and Control, McGraw Hill Pub., New York. 7) Vyas R.P. : Process Control and Instrumentation, Central Techno Pub., Nagpur. 8) Patranabis D. : Principles of Industrial Instrumentation, 2nd ed., Tata McGraw Hill Pub. Co., New Delhi. 9) Patranabis D. : Principles of Process Control, Tata McGraw Hill Pub. Co., New Delhi. 10) Gaikwad R.W., Misal S.A. : Process Dynamics & Control, Central Techno Pub., Nagpur. 11) Stephanopoulos G. : Chemical Process Control and Introduction to Theory & Practice, PHI, Latest Edition. 12) Considine D.N.: Process Instrumentation & Control Handbook, McGraw Hill. Subject Code No.: CED-352 Teaching Scheme: SubjectTitle: Chemical Process Technology Class Test: 20 marks Theory: 3 hrs/week Theory Examination (Duration): 3 hrs Tutorial: 1hr/week Theory Examination (Marks): 80 Credits: 4 Course Objectives : The main objective of this course is to familiarize students with various industrial processes. The vital role of industries in catering the needs of society would be underlined. Students are expected to learn and understand steps that are followed while converting a raw material into finished product. Symbolic representation of various unit operations, Coal Chemicals, Carbonization of Coal, Construction and working of Gasifiers, Gaseous fuels, Producer Gas, Water Gas, Natural Gas, Industrial gases- Manufacture of carbon dioxide, Oxygen, Nitrogen etc Unit-II : Manufacture of Industrial alcohol, Absolute alcohol, Manufacture of Vinegar and acetic acid, Citric acid, Lactic acid, Tartaric acid, Manufacture of synthetic flavors and colors used in food and Pharma industries Unit-III : Manufacture of pulp and paper, Chlor alkali industry, Manufacture of glass, Manufacture of detergent and soap, Paints and pigments-formulation, composition and related properties of paint, manufacture of various pigments Unit-IV : Manufacture of Starch, Manufacture of sugar, Manufacture of various oils and fats, Oil extraction, Analysis of oil and fats, Hydrogenation of oil, processing of oil, fat and waxes Unit-V : Sulpha drug manufacture, manufacture of Penicillin, Introduction to Fine chemicals Unit-VI : Polymerization concept, Classification of polymers, manufacture of Nylon, Polyethylene, Polyvinyl chloride etc Text Books : 1. Shreve’s Chemical Process Industries; George T. Austin; Mc. Graw Hill 2. Outlines of chemical Technology; Charles E. Dryden 3.Industrial and manufacturing chemistry; Part-II;Volume-I and II Geoffry Martin, Willfrid Francis 4.Unit Process In Organic Syntheis; P.H Groggins 5.Analysis, synthesis and design of chemical processes; Turton, Bailie,Whiting, Shaeiwitz 6.Roger’s Industrial Chemistry; Volume-I; Roger’s and Furnas 7.Fine chemicals manufacture, technology and engineering; A.Cybulski, J.A.Moulinj, M.M.Sharma, R.A.Sheldon 8.Fine Chemicals The industry and the business; Peter pollak Subject Code No.: FTD-353Subject Title: Food Processing Technology- IV (Spices & Flavor Tech) Class Test: 20 marks Teaching Scheme: Unit-I Theory: 3 hrs/week : Theory Examination (Duration): 3 hrs Theory Examination (Marks): 80 Tutorial: Credits: 3 Course Objectives : To makestudents acquainted with the processing technology of spices and flavor. Unit-I : Unit-II : Unit-III : Unit-IV : Unit-V : Unit-VI : Text Books : Production and processing scenario of spice, flavour & plantation crops and its scope. Major spices: Post harvest technology, composition and processed products of following spices and nuts (1) ginger (2) chilli (3) turmeric (4) onion and garlic (5) pepper (6) cardamom (7) arecanut, (8) cashew nut, (9) coconut. Minor spices, herbs and leafy vegetables, Processing and utilization of all spice, anise seed, sweet basil, caraway seed, cassia, cinnamon, clove, coriander, cumin, dill seed, fern seed, nutmeg, malt, mint marjoram, rose merry, saffron, sage, savoury, thyme, ajowan, asafoetida, curry leaves. Tea- types, processing, quality control. Coffee and cocoa processing. Flavour of major spices. Spice oil and oleoresins. Flavours of minor spices. Vanilla and annatto processing. Standard specifications of spices. Flavours of soft drinks, baking and confectionery. Functional packaging of spices and spice products. 1. NIIR. 2004. Handbook on Spices. National Institute of Industrial Research Board, Asia Pacific Business Press Inc. 2. Kenneth T. Farrell (1985). Spices, condiments and seasonings. The AVI Pub. Company. 3. Kenji Hirasa and MitsnoTakemasa(1998). Spice Science and Technology, Marcel Dekker, Inc. 4. Major Spices of India: Crop Management and Post Harvest Technology. J.S.Purthi, ICAR publication, 1st Edition, 2003. 5. Minor Spices and Condiments: Crop Management and Post Harvest Technology. J.S.Purthi, ICAR publication, 1st Edition, 2001. 6. Tree Nuts: Production, Processing, Products. J. G. woodruff, AVI Pub. Co., 1st Edition, 1979. 7. Tea Production and Processing. B. Banerjee, Oxford & IBH Pub. Co., 1st Edition, 1993. 8. Coffee Technology. M. Sivetz, AVI publishing Co., 1st Edition, 1979. Minifie BW. 1999. Chocolate, Cocoa and Confectionery Technology. 3rd ed. Aspen Publ. Subject Code No.: PTD-353Subject Title: Pharmaceutical Analysis-II Class Test: 20 marks Teaching Scheme: Theory: 3 hrs/week Theory Examination (Duration): 3 hrs Tutorial: Theory Examination (Marks): 80 Credits: 3 Course Objectives : To understand basic concepts of different spectrophotometric & chromatography techniques used in Pharmaceutical Analysis. Unit-I : Unit-II : Unit-III : Unit-IV : Unit-V : Unit-VI : An introduction to instrumental methods Classification of instrumental techniques, important consideration in analytical method, basic function of instrumentation, Electromagnetic radiation, spectoscopy UV visible spectrophotometry Beer’s Law, Lambert’s Law, Beer-Lambert’s law, Limitations UV visible absorption spectra, Hypochromic shift, Hyperchromic shift, Bathochromic shift, Hypsochromic shift, Instrumentation (Single and Double Beam) Infra-Red Spectrophotometry Introduction, range of IR radiations, requirement of compounds to absorb IR radiation, modes of vibrations, stretching and bending, interpretation of IR spectra, sample preparation, solvent used in IR, Instrumentation and application. Nuclear Magnetic Resonance Spectroscopy The NMR Phenomenon, Theory of NMR, Instrumentation, Chemical shift and its measurement, Factors influencing chemical shift, Solvent used in NMR, Spin-Spin coupling, Spin-Spin splitting, Application of Proton NMR, Introduction to C-13 NMR. Molecular Luminescence spectrophotometry Introduction, Theory of Fluorescence and Phosphorescence, Factors influencing Fluorescence and Phosphorescence, Instrumentation, Applications. Mass Spectrometry Basic Principle, Instrumentation, Isotope abundance, The Molecular ion, Metastable ion, Applications. Thermal Analysis Introduction to Thermal methods of analysis, Introduction to Thermogravity (TG), Isothermal or Static Thermogravimetry, QuasistaticThermogravimetry, Recording of results, Information from TG curves, Factors affecting Thermogravimetric Curve, Instrumentation of Thermogravimetry, Applications of TG, Introduction to DTA and DSC. Chromatography Introduction, Classification, Theory, Column chromatography, Paper Chromatography, Thin Layer Chromatography, High Performance Liquid Chromatography, Gas Solid Chromatography, Gas Liquid Chromatography, HPTLC. Text Books : k) l) m) n) o) p) q) r) s) t) Subject Code No.: FTD-354 Beckett A.H, Stenlake J.B., “Practical Pharmaceutical Chemistry – Part One”, IV editon, CBS Publishers and Distributors, New Delhi. Jeffery G.H., Bessett J., Mendham J., Denney R.C., “Vogel’s Textbook of Quantitative Chemical Analysis”, V Editon, ELBS Publications, London. KarAshutosh, “Pharmaceutical Drug Analysis”’ II edition, New Age International Publisher, New Delhi. Sheorey S., Honrao M., “Pharmaceutical Analysis- I (Practical)”, I edition, Career publications, Nashik. Connors K.A., “A textbook of Pharmaceutical Analysis”, III edition, Orient Longman Publications. Mann & Saunders, “practical organic chemistry”, IV edition, Orient Longman Publications. Higuchi et al., “Pharmaceutical Analysis”, CBS Publishers, New Delhi Garratt D.C., “The Quantitative Analysis of Drugs”, II edition, Sunders, New York. Atherden L.M., “Bentley & Driver’s Textbook of Pharmaceutical Chemistry”, VIII edition, Oxford University Press, Mumbai. Pharmacopoeia of India, Vol. I & II Controller of Publications, Govt. of India, New Delhi. Subject Title: Bakery & Confectionary Technology Teaching Scheme: Class Test: 20 marks Theory: 3 hrs/week Theory Examination (Duration): 3 hrs Tutorial: Theory Examination (Marks): 80 Credits: 3 Course Objectives : To get acquainted with the processing technology of Bakery and Confectionery products Unit-I : Unit-II : Unit-III : Unit-IV : Unit-V : Milling of wheat- Roller flour milling process, break rolls, reduction roll, design and operation of wheat milling process. Physicochemical and Rheological properties of dough. Bakery products-Role of bakery ingredients, bread making methods i.e. straight and sponge dough method, Quality control and testing of raw material, testing of final product, bread faults, staleness and roppiness in bread Baked products from soft wheat-Cookies, Biscuits, cakes, role of ingredients, faults and remedies. Setting of bakery unit, bakery norms, specifications for raw materials packaging, marketing of products, project report preparation Confectionery Technology- History, traditional confectionery goods, types of confectionery. Raw materials/ Ingredients-sugar, sugar qualities, physical, chemical properties dextrose, fructose, lactose, caramel, maltose, honey, sorbitol, mannitol, soya maltose, isomalt etc. High boiled sweets- Introduction, composition, properties of high boiled sweets, preparation of high boiled sweets, different types of high boiled sweets. Chocolate processing technology- Ingredients, mixing, refining, conching, tempering, molding, cooling, coating, fat bloom. Unit-VI : Text Books : Toffee- Definition, composition, types of toffee ingredient and their role, batch and continuous method of toffee. Fondents-Fudge/ Creamy- Ingredients, methods, productivity lozenges- definition, manufacturing methods, composition, faults and remedy. Packaging requirements of bakery and confectionery products. 1. Bakery science and Cereal Technology- NeelamKhetarpaul 2. Technology of Cereals- Kent. 3. Basic Baking- S.C. Dubey. 4. Flour Milling Process-Scott 5. Sugar Confectionery and Chocolate Manufacture- R. Less and E.B. Jackson 6. Chocolate, Cocoa & Confectionery Sci. & Tech.- Bernared W. Minifie 7. Industrial Chocolate Manufacture and use-S.T. Beekelt I. Subject Code No.: PTD-354Subject Title: Phytochemistry Teaching Scheme: Class Test: 20 marks Theory: 3 hrs/week Theory Examination (Duration): 3 hrs Tutorial: Theory Examination (Marks): 80 Credits: 3 Course Objectives : Unit-I : Unit-II : Unit-III : Unit-IV : Unit-V : Unit-VI : Text Books : To understand the basic concepts of phytochemistry of natural crude drugs Diagnostic features and medicinal significance of Angiosperm including the families:Apocynaceae, Solanaceae, Rutaceae, Umbillifereae, Leguminoseae and Liliaceae. Chemical constituents of Medicinal plants – Primary metabolites:Carbohydrates, Lipids, Proteins. Secondary metabolites – Alkaloids, Glycosides (Anthraquinones, Cardiac, Saponins, cyanogenetic, Flavanoids, Isothiocyanates, coumarins.) Tannins, volatile oils (Terpenoids). a. Definition and method of extraction, chemistry and method of analysisb. Study of method of production, chemical constituents, tests, uses, and adulterants of following:i) Castor oilii) Arachis oiliii) Almond oiliv) Codliver oil v) Shark liver oil vi) Spermaceti vii) Cocoa butter GLYCOSIDES:Definition, classification, general properties, source, general method of isolation,estimation, diagnostic characters, chemistry, adulterantsand uses. a. Cardiac glycosides: Digitalis, strophanthus, squill, thevetiab. Anthracene glycosides:Senna, aloe, rhubarb, cascarac. Saponin glycosides:dioscorea, asparagus, solanum species, safedmusali,liquorice, brahmi. d. Cyanogenetic glycosides: wild cherry bark, bitter almonde. Isothiocyanates glycosides: mustardf. Bitter glycosides:kalmegh, picrorhizag. Coumarin glycosides:psroalea, visnage, ammih. Flavonoid glycosides:orange peel, lemon peel, and gingko.i. Aldehyde glycosides: vanillaj. Phenol glycosides: bearberry. TANNINS:Definition, properties, classification, general method of isolation, estimation,uses, adulterants of the following class of drugs:i) Catechu ii) tannic acid iii) nut galls iv) ashoka v) arjunavi) behera vii) myrobalans Naturalfibers:Detailed study and pharmaceutical importance of following naturalfibers:Cotton jute, hemp, silk, wool 1. AshutoshKhar, Pharmacognosy and Pharmaco-biotechnology, New Age International Publishers. 2. Jean Bruneton., Pharmacognosy and Phytochemistry, Lavosier Publisher U.K. 3. Trease and Evans, Pharmacognosy, W. B. Saunders, New York 4. V. E. Tylor, L. R. Brady and S. B. Robbers, Pharmacognosy, K.M. Varghese Co.Bombay. 5. Indian Herbal Pharmacopoiea, K. M. Varghese Co.Bombay. 6. Kokate C.K Purohit A.P and Gokhale S.B, Pharmacognosy, NiraliPrakashan. 7. V. V. Sivarajan, Introduction to the Principles of Plant Taxonomy, Syndicate of university of Cambridge 8. O P. Sharma, Plant Taxonomy, Tata McGraw-Hill Education 9. V.D. Rangari, Pharmacognosy and Phytochemistry, Vol.1 & 2. Subject Code No.: FTD-355Subject Title: Food Safety & Quality Class Test: 20 marks Teaching Scheme: Theory: 3hrs/week Theory Examination (Duration): 3hrs Tutorial: Theory Examination (Marks): 80 Credits: 3 Course Objectives : To makestudents acquainted with various aspects of food safety, quality and risk assessment and management Unit-I : Unit-II : Unit-III : Unit-IV : Unit-V : Unit-VI : Concept of food safety &quality: Quality attributes- chemical, nutritional, microbial, physical and sensory; their measurement and evaluation; sensory panel. Hazards in food chain physical, chemical, biological; Toxins in food, naturally occurring, bacterial and fungal. Intrinsic toxins produced during processing and storage, Metals as toxins – sources, contamination, toxicity and elimination. Pesticide residues as toxini) Chlorinated ii) Non – chlorinated. Permitted and non permitted food additives as and when amended. Organic foods. Microbial standards of fresh and processed foods. Global Food safety Initiatives. Indian & International quality systems and standards like ISO and Food Codex.Pre requisite programs, food safety policies. HACCP, BRC, SQF, Global GAP and other quality management systems. Food adulteration and food safety. Quality management systems in India,sampling procedures and plans. Various organizations dealing with inspection, risk analysis, traceability and authentication, certification and quality assurance (AGMARK, BIS). Domestic regulations. Food Safety and Standards Act, 2006. Export import policy, export documentation. Quality manuals, documentation and audits. Laboratory quality procedures and assessment of laboratory performance. Applications in different food industries. IPR and Patents. Text Books : 9. Food Quality Assurance-InteazAlli 10. Quality Control in Food Industry- Krammer A &Twigg BA.1973. Vol. I, II. AVI Publ. 11. Sensory Evaluation of Food - Theory and Practice- Jellinek G. 1985. Ellis Harwood. 12. Food Hygiene and Sanitation-S. RodaySafety of Foods (II Edition)-H.D. Graham 13. Guide to Quality Management Systems for Food Industries. Blackie Academic- Early R.1995. 14. Food Chemistry (New Edition)-Owin R. Fenema 15. Food Microbiology-W.C. Frazier and D.C. Westhoff 16. Food Microbiology-M.R. Adams and M.O. Moss 17. Handbook of Food Toxicology-S.S. Deshpande 18. Food Additives Toxicology-J.A. Maga and A.T. Tu 19. Regulatory status of Direct Food Additives- Furia TE.1980. CRC Press. 20. Food safety and Food quality 1st Edition- Harrison R M 21. Food Safety & Quality Assurance, 2nd Edition-Hubbert 22. http://www.fssai.gov.in/ http://www.codexalimentarius.org/ Subject Code No.: PTD-355Subject Title: Physical Pharmacy Class Test: 20 marks Teaching Scheme: Theory: 3hrs/week Theory Examination (Duration): 3hrs Theory Examination (Marks): 80 Tutorial: Credits: 3 Course Objectives : Unit-I : Unit-II : Unit-III : Unit-IV : Unit-V : To learn and understand basic concept and principles of physical pharmacy. Composition &Physical States of Matter Intermolecular forces &their impact on state of the matter. Various physical properties of matter, dipole moment, dielectric constant, VanDerwaal’sequation &critical phenomenon, liquefaction of gases, aerosols. Colligative Properties The liquid state, vapor pressure, ideal & real solutions. Raoult’slaw, elevation of boiling point, depression of freezing point, osmotic pressure, determination of molecular weight based on colligative properties. Phase Rule One, two, & three component systems along with their applications. Solid- solid, solid - liquid, & liquid-liquid systems. Solutions Solubility, factors affecting solubility, solubility curves. Types of solutions, effect of co-solvency, pH &other factors on solubility. Solubility of gases in liquids, liquids in liquids, &solids in liquids, critical solution temperature, law of partitioning &its applications. Solute solvent interactions. Micromeritics: Particle size and distribution, average particle size number and weight distribution, particle number, method of determining particle size and volume, optical microscopy, sieving, sedimentation, determining surface areas, permeability, adsorption, derived properties of powders, porosity, packing arrangement densities, bulkiness and flow properties. Surface and Interfacial Phenomenon: Liquid interface, surface and interfacial tensions, surface free energy, measurement of surface and interfacial tension, spreading coefficient, adsorption and liquid interfaces, surface active agents, HLB classification, solubilization, detergency, absorption at solid interfaces, solid gas and solid liquid interfaces, complex films, electrical properties of interfaces. Viscosity and Rheology: Newtonian systems, law of flow, kinematics viscosity, effect of temperature, non Newtonian systems, pseudoplastics, dilatant, plastic, thixotropy in formulations, determination of viscosity and thixotropy by capillary, falling ball, rotational viscometer, application of rheology in pharmacy. Dispersion systems: Colloidal dispersions: Definition, types, properties of colloids, protective colloids, application of colloids in pharmacy. Unit-VI : Text Books : 1.Glasstone, Samuel, Text Book of Physical Chemistry, McMilan Publishers 2. Carstensen, J.T., Advanced Pharmaceutical Solids, MarcelDekker 3. Connors, K.A., Chemical Stability Of Pharmaceuticals, WileyJ. 4. Martin, Alfred, Physical Pharmacy, Waverley Publishers 5. Conners,K.A., Thermodynamics Of Pharmaceutical Systems, WileyJ. 6. Raymond, Chang, Physical Chemistry with Applications to BiologicalSystem, CollierMcMilanInternationalEd. Subject Code No.: FTD-356Subject Title: Food Processing Tech-V (Meat, Fish & Poultry Processing) Class Test: 10 marks Teaching Scheme: Theory: 2hrs/week Theory Examination (Duration): 2hrs Tutorial: Theory Examination (Marks): 40 Credits: 2 Course Objectives : Unit-I : Unit-II : Unit-III : Unit-IV : Unit-V : Unit-VI : Text Books : To get acquainted with the processing technology of meat, fish and poultry products. Present status and prospects of meat, fish and poultry processing industries in India and importance in national economy. Meat muscle structure, chemical composition and physico-chemical properties of meat muscle, types of meat and meat animals. Pre-slaughter care of animals, abattoir design and layout, anti mortem inspection, methods of slaughtering, dressing, cutting, post mortem inspection, judging and grading of wholesale and retail cuts of meat. Post mortem changes-rigor mortis and factors affecting biochemical changes. Poultryegg structure, composition, quality characteristics, processing and preservation of eggs. Eggs products. Types of fish, quality characteristics, dressing of fish, preservation of fish by drying, salt curing, smoking and freezing. Fish products. Processing and preservation of meat-mechanical deboning, aging or chilling, freezing, pickling, curing, cooking and smoking of meat. Meat tenderization. Meat products. Meat plant sanitation and hygiene. Byproducts utilization of abattoir, poultry and fish processing industries. 1. Principles of meat Science- Forrest F J 2. Meat Hand Book- Albert Levie 3. Developments in Meat Science-Ralston Lawrie 4. Poultry Production-Singh R A 5. Fish Processing in India-ICAR Subject Code No.: PTD-356Subject Title: Biopharmaceutics Teaching Scheme: Class Test: 10 marks Theory: 2hrs/week Theory Examination (Duration): 2hrs Tutorial: Theory Examination (Marks): 40 Credits: 2 Course Objectives : Unit-I : Unit-II : Unit-III : Unit-IV : Unit-V : Unit-VI : To understand basic concepts of Biopharmaceutics & Pharmacokinetics. Introduction: Definitions of absorption, distribution, metabolism, excretion, half life, first pass metabolism, entero-hepatic cycling, bioavailability, biopharmaceutics, pharmacokinetics, pharmacodynamics, bioequivalence. Absorption: Physiology of GIT & cell membranes, fluid mosaic model. Mechanism of drug absorption: passive diffusion, active transport, facilitated diffusion, ion pair transport, paracellular transport, vesicular transport. Factors affecting bioavailability: Biological Factors: Gastric emptying, GI pH, interaction with food & normal GI constituents, diseased state, blood flow to GIT, drug stability in GIT. Physicochemical factors: Effect of pH, pKa&lipophilicity of drug (pH partition hypothesis) Dissolution: Diffusion theory, surface renewal theory, limited salvation theory, methods to enhance dissolution, polymorphism, salt formation, hydrates/solvates, complexation. Introduction to Biopharmaceutical Classification system. Distribution: Factors affecting distribution, Physicochemical factors, Physiological factors, various barriers for drug distribution, miscellaneous factors like age, diet, diseased state, obesity, drug interactions. Apparent volume of distribution and its measurement. Elimination of drug: Principle processes in urinary excretion, factors affecting renal excretion, concept and estimation of clearance, organ clearance, hepatic clearance, factors affecting hepatic clearance. Non renal routes of excretion: salivary, mammary, pulmonary, skin/dermal, gastro intestinal. Dosage regimen: Design of dosage regimen, dose size, dosing frequency, fluctuations, steady state concept, time required to reach steady state, loadingdose, maintenance dose, individualization of dosage. Introduction to pharmacodynamic: Drug concentration and pharmacological response, therapeutic Text Books : window, graded and quantal response, pharmacodynamic models, linear model, logarithmic model, E-max model, intensity and duration of action-concentration relationship Bioavailability and bioequivalence: Absolute and relative bioavailability, purpose of bioavailability study, protocol and study design for bioavailability, wash out period, reference and test products, methods for estimation of bioavailability: plasma data, urine data. Concept of IVIVC. 1. LeonShargel,, Comprehensive Review of Pharmacy, Lippincott 2. MiloGibaldi, Bio Pharmaceutics and Clinical Pharmacokinetics, Marcel Dekker Inc.USA 3. WellingandTSE, Pharmacokinetics Regulatory, Industrial andAcademic Prospectives(Vol.57), Marcel Dekker Inc.USA 4.WillingandTSE, Pharmaceutical Bioequivalence (Vol.48), Marcel Dekker Inc.USA 5. MadanP.I., Biopharmaceutics and Practical Pharmacokinetics, Whittier Publications Subject Code No.: CED-371SubjectTitle: Lab. VI- Instrumentation & Process Control Teaching Scheme: Practical/Term Work: 3hrs/week Teachers Assessment: 25 marks Credits: 1 End Semester Examination: 25 marks Course Objective : To acquaint the students with instrumentation and process control system followed in the industry. List of Practicals (Not Less than 10) 1. Time Constant of mercury thermometer 2. Response of single tank liquid level system 3. Dynamics of mercury manometer – under damped 4. Dynamics of thermocouple. 5. Dynamics of two tank liquid level system without interaction. 6. Dynamics of two tank liquid level system with interaction. 7. Dynamics of thermal system (Batch Heater) 8. Dynamics of liquid level system with proportional control. 9. Dynamics of mercury manometer- Over damped Data acquisition, ADC and use of DAC. List of Reference Books 1) Industrial Instrumentation : Eckman, Wiley Eastern 2) Instrumental Methods of Chemical Analysis :Erwing, McGraw Hill. 3) Instrumentation & Process Measurements : W.Bottom, Orient Longman. 4) Industrial Control &Instrumentation :W.Bottom, Orient Longman. 5) Outlines of Chemical Instrumentation & Process Control : A. Suryanarayan, Khanna Pub., New Delhi. 6) Donald R. CoughaNowr : Process Systems Analysis and Control, McGraw Hill Pub., New York. 7) Vyas R.P. : Process Control and Instrumentation, Central Techno Pub., Nagpur. 8) Patranabis D. : Principles of Industrial Instrumentation, 2nd ed., Tata McGraw Hill Pub. Co., New Delhi. 9) Patranabis D. : Principles of Process Control, Tata McGraw Hill Pub. Co., New Delhi. 10) Gaikwad R.W., Misal S.A. : Process Dynamics & Control, Central Techno Pub., Nagpur. 11) Stephanopoulos G. : Chemical Process Control and Introduction to Theory & Practice, PHI, Latest Edition. 12) Considine D.N. : Process Instrumentation & Control Handbook, McGraw Hill. List of Equipments /Instruments Subject Code No.: CED-372SubjectTitle: Lab. VII- Chemical Process Technology Teaching Scheme: Practical/Term Work: 3hrs/week Teachers Assessment: 25 marks Credits: 1 End Semester Examination: 25 marks Course Objective : List of Practicals 1. 1.Preparation of Soap (Not Less than 10) 2. 2.Preparation of Detergent 3. 3.Preparation of yellow Pigment 4. 4.Preparation of blue Pigment 5.Preparation of Nylon 6,6 polymer 6.Determination of Saponification value of fat 7.Determination of iodine value of fat 8.Determination of acid value of fat 9.Preparation of biodiesel 10.Extraction List of Reference Books 5. List of Equipments /Instruments 6. Subject Code No.: FTD-373SubjectTitle: Lab. VIII- Food Processing Technology-IV (Spices & Flavor Tech) Teaching Scheme: Practical/Term Work: 4hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objective : To make students acquainted with different techniques of processing and preservation of spices and flavor. List of Practicals (Not Less than 10) 1. Identification and characterization of flavouring compounds of spices. 2. Study of standard specification of spices. 3. Chemical analysis of spices moisture, valuable oil, specific gravity, refractive index, acid value. 4. Valuable oil determination. 5. Extraction of oil from clove, pepper, cardamom-chili. 6. Extraction of oleoresins-Turmeric, ginger, pepper, clove. 7. Steam distillation of spices. 8. Piperine estimation in pepper oleoresin. 9. Determination of curumin content in turmeric. 10. Preparation of curry powder 11. Packaging study of spices Visit to spices processing/flavor industry. List of Reference Books 1. AOAC (2002). Official Methods of Analysis, 16th Ed., Association of Official Analytical Chemists Washington, DC. 2. 2. http://www.fssai.gov.in/ 3. 3. http://www.codexalimentarius.org/ List of Equipments /Instruments 4. Soxhlet apparatus, Distillation unit Subject Code No.: PTD-373SubjectTitle: Lab. VIII- Pharmaceutical Analysis-II Teaching Scheme: Practical/Term Work: 4hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objective : List of Practicals (Not Less than 10) List of Reference Books 2. To make students acquainted with different techniques of Pharmaceutical Analysis. A) Practicals: 1. Calibration of pH meter 2. To determine the pka value of dibasic acid using pH meter 3. To determine the pka value of tribasic acid using pH meter 4. Calibration of conductometer and estimation of conductivity of distilled water 5. Calibration of UV-Vis spectrophotometer as per IP 6. Effect of pH and solvent on UV spectrum of given compound 7. Assay of following formulations or drugs using UV-Vis spectroscopy as per IP Propranolol tablet, paracetamol tablet, atenolol tablet, rifampicin/ rifampicin capsule, albendazole tablet 8. Estimation of salicylic acid by colorimetry 9. Assay by fluorimetry of a given drug eg; Quinine sulphate 10. Preparation and activation of chromatographic plate 11. Separation of given mixture of amino acid by using TLC 12. Separation of mixture of amino acid using paper chromatography B) Demonstration Experiments 1. Demonstration of IR 2. Demonstration of DSC 3. Demonstration of HPLC 1. Silverstein R. M., G. C. Bassler Spectrometric Identification Of Organic Compounds John Wiley & Sons, New York. 2. Dyer J. R., Applications Of Absorption Spectroscopy Of Organic Compounds Englewood, U S A. 3. United State Pharmacopoea U. S. Govt. 4. B. P. Commission British Pharmacopoea H. M. S. O. London 5. Govt. of India Indian Pharmacopoea The Controller of Publications Delhi 6. Walter Lund British Pharmaceutical Codex The Pharm London National Formulary Royal Londons List of Equipments/Instruments 5. pH meter, Conductometer, UV-Vis spectrophotometer, colorimeter, by fluorimeter, IR, DSC, HPLC 6. Subject Code No.: FTD-374SubjectTitle: Lab. IX- Bakery & Confectionary Technology Teaching Scheme: Practical/Term Work: 4hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objective : List of Practicals To get acquainted with different techniques of processing and preservation bakery and confectionery products. 1. Determination of gluten content in wheat flour sample 2. Determination of dough raising capacity of wheat flour. (Not Less than 10) 3. Manufacturing technology of bread making. 4. Manufacturing technology of cake and cookies making. 5. Manufacturing technology of biscuit making. 6. Manufacturing technology of different chikki 7. Manufacturing technology of Chocolate. 8. Manufacturing technology of fruit toffee. 9. Manufacturing technology of fruit candy. 10. Manufacturing technology of high boiled sweets. 11. Manufacturing technology of Nan- Katie. 12. Visit to bakery and confectionery industry. List of Reference Books List of Equipments /Instruments 7. Subject Code No.: PTD-374SubjectTitle: Lab. IX- Phytochemistry Teaching Scheme: Practical/Term Work: 4hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks List of Practicals To get acquainted with different techniques of extractions and its analysis. 1. Extraction of sennoside as a calcium salt from senna. (Not Less than 10) 2. Extraction of curcumin from rhizomes of turmeric. Course Objective : 3. Extraction of Ammonium glycerrhizate from liquorice. 4. Extraction of Hesperidins from orange peel. 5. Extraction of total saponin from fenugreek 6. Extraction of caffine from Tea powder 7. Extraction of Nicotine from tobacco 8. Extraction of vasicine from vasaka. 9. Extraction of eucalyptus oil. 10. Extraction of Tannic acid from Myrobalon. 11. Study TLC of Calcium sennoside with Kayamchurna 12. Study TLC of curcumin with Bajranglep. 13. Study TLC of Piperine for Triphalachurna. 14. Study of Marketed Nilgiri oil with extracted oil. 15. To determine total citral contain in lemonoil. 16. To estimate Total Triterpenoids by colorimetric Method 17. ToEstimate Rutin byUV-Visible spectrophotometric method. List of Reference Books 1. Wallis T. E., Textbook of Pharmacognosy, CBS, Delhi 2. Jean Bruneton., Pharmacognosy and Phytochemistry, Lavosier Publisher U.K. 3. Wagner and Bladt, Plant Drug analysis, Springer U.K. List of Equipments /Instruments 4. V. E. Tylor, L. R. Brady and S. B. Robbers, Pharmacognosy, K.M. Varghese Co.Bombay. 5. Indian Herbal Pharmacopoiea, K. M. Varghese Co.Bombay. Soxhlet apparatus, Distillation unit Subject Code No.: FTD-375SubjectTitle: Lab. X- Food Safety & Quality Teaching Scheme: Practical/Term Work: 3hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objective List of Practicals (Not Less than 10) : To make students acquainted with food safety and quality management system followed in the laboratory and industry. 1. Study of national and international quality standards for different fresh and processed foods. 2. Estimation of Salmonella /Shigella/ Stachyphylococcus from food samples 3. Isolation and identification of Listeria and E. Coli 4. Estimation of fungal toxins from food samples. (Different types of foods) 5. Detection of heavy metal (lead, arsenic, mercury etc.) from foods. 6. Detection and estimation of food additives and adulterants. 7. HACCP for food industries by taking few models 8. Preparation of HACCP chart 9. Preparation of quality policy & documentation 10. Visit to export oriented food processing industry Visit to food testing/public health laboratory. List of Reference Books List of Equipments /Instruments 1. Training Manual for food safety and quality. 2. AOAC (2002). Official Methods of Analysis, 16th Ed., Association of Official Analytical Chemists Washington, DC. 3. Laboratory methods in food microbiology-W. F. Harrigan 4. Food Quality Assurance-InteazAlli 5. HACCP System and Guidelines for Its Application, Codex Alimentarius Commission, Joint FAO/WHO Food Standards Programs 6. http://www.fssai.gov.in/ http://www.codexalimentarius.org/ Atomic Absorption Spectrophotometer. Viscometer, Gas Chromatography/Mass Spectrometry (GC/MS) system, High Pressure Liquid Chromatography (HPLC), Thin Layer Chromatography, Autoclave, Incubator Subject Code No.: PTD-375SubjectTitle: Lab. X- Physical Pharmaceutics Teaching Scheme: Practical/Term Work: 3hrs/week Teachers Assessment: 25 marks Credits: 2 End Semester Examination: 25 marks Course Objective List of Practicals (Not Less than 10) : To make students acquainted with different practical aspects of Physical Pharmaceutics.. 1. To determine molecular weight of (anthracene/ phenanthrene) by Beckman’s thermometer method 2. To determine the upper consolute temperature and composition of phenol -water system 3. To determine the effect of impurity on upper consolute temperature of phenol water system 4. To determine the refractive index and refrachor of given sample having molecular weight 5. To determine the molecular weight of given sample by Rast’s camphor method 6. To determine partition coefficient of benzoic acid / salicylic acid / iodine in chloroform / benzene water system 7. To determine the energy of activation of methyl / ethyl acetate hydrolysis 8. To determine the surface tension and parachore of given sample using stalagmometer 9. To determine the specific surface of charcoal using acetic acid adsorption 10. To determine the specific surface of charcoal using acetic acid adsorption 11. To determine critical micellar concentration (CMC) of given ionic surfactant by conductometric measurement 12. To determine the effect of surfactant (tween 80) on solubility of salicylic acid 13. To determine the effect of electrolyte on sedimentation of calamine suspension 14. To determine the particle size distribution of an emulsion using optical microscopy 15. To determine the particle size distribution using sieve analysis 16. To study the effect of lubricant on flow property of given powder 17. To determine the various densities and porosity of given powder system 18. To determine the viscosity and rheogram of given sample of liquid 19. To determine the molecular weight of PVP / PVA using Oswald’s List of Reference Books List of Equipments /Instruments viscometer 20. To demonstrate viscosity measurement using Brookfield’s viscometer 1. Kim CherhgJu, Advance Pharmaceutical Physicochemical Principles, CRC Press 2. M.E.Aulton, Pharmaceutics: The Science of Dosage Form Design, Churchill Livingstone 3. MartinAlfred, Physical Pharmacy, Lippincott 4. MooreW.J., Physical Chemistry 5. RaymondChang, Physical Chemistry for Biosciences, University Sciences Books 6. GinnaroA.R., "Remington:Thescience and Practice of Pharmacy", Mack Publishingcompany. Stalagmometer, conductometer, optical microscope, sieves, Oswald’s viscometer, Brookfield’s viscometer