Cafeteria roenbergensis virus (CroV)

BME 130 – Genomes
Lecture 16
Alternative genome
anatomies
(Viruses and mobile
elements)
Genomes in the news
Cafeteria roenbergensis virus (CroV), has a genome that's over 700,000
base pairs long (700 kilobases, or kb).
About half of the virus' genes are similar to those of something from either other giant
viruses or living cells, with pieces from all three domains of life (eukaryotes, bacteria, and
archaea). But the majority of genes have no known function, so it's hard to know what to
make of them. Some of the ones that are present, however, are pretty sophisticated. The
virus has its own DNA repair system, and can hijack a system its host uses to destroy
unwanted proteins; it uses this to get rid of the host's defense proteins. It also seems to
have picked up 38kb from a bacteria (potentially, one of the meals of its host) that
encodes for a pathway that attaches sugars to proteins.
http://arstechnica.com/science/news/2010/10/giant-virus-found-in-tiny-predator.ars
http://www.pnas.org/content/early/2010/10/15/1007615107.abstract
Bacteriophages
Figure 9.1 Genomes 3 (© Garland Science 2007)
Table 9.1 Genomes 3 (© Garland Science 2007)
Overlapping ORFs
Figure 9.2 Genomes 3 (© Garland Science 2007)
Figure 9.3 Genomes 3 (© Garland Science 2007)
Lytic infection
Figure 9.4a Genomes 3 (© Garland Science 2007)
Figure 9.4b part 1 of 2 Genomes 3 (© Garland Science 2007)
Figure 9.4b part 2 of 2 Genomes 3 (© Garland Science 2007)
Lysogenic
infection
Figure 9.5 Genomes 3 (© Garland Science 2007)
Eukaryotic retrovirus structure
Figure 9.6 Genomes 3 (© Garland Science 2007)
Table 9.2 Genomes 3 (© Garland Science 2007)
Figure 9.7 Genomes 3 (© Garland Science 2007)
Figure 9.8 Genomes 3 (© Garland Science 2007)
Figure 9.9a Genomes 3 (© Garland Science 2007)
Figure 9.9b Genomes 3 (© Garland Science 2007)
Figure 9.10 Genomes 3 (© Garland Science 2007)
Figure 9.11 Genomes 3 (© Garland Science 2007)
Figure 9.12 Genomes 3 (© Garland Science 2007)
Figure 9.13 Genomes 3 (© Garland Science 2007)
Figure 9.14 Genomes 3 (© Garland Science 2007)
Table 9.3 Genomes 3 (© Garland Science 2007)
Figure 9.15 Genomes 3 (© Garland Science 2007)
Figure 9.16 Genomes 3 (© Garland Science 2007)
Figure 9.17 Genomes 3 (© Garland Science 2007)
Figure 9.18 Genomes 3 (© Garland Science 2007)
Figure 9.19 Genomes 3 (© Garland Science 2007)
Figure 9.20 Genomes 3 (© Garland Science 2007)
Drosophila phylogeny
and P-elements