SR - Vinnova
Transcription
SR - Vinnova
Centre for bio- and chemical sensor science and technology S-SENCE the Swedish Sensor Centre Summary report 1995-2006 Partners: AppliedSensor AB Otre Asko Cylinda AB Pharmacia & Upjohn Assi Domän Carton Senset Biacore AB SKL Billerud AB SLR Biosensor Applications AB Stora Enso Duni/Finess Tekniska Verken i Linköping AB Eka Chemicals Tetra Pak Ford Motor Company Vattenfall Global Homeostasis Institute Volvo Powertrain Iggesund Paperboard Volvo PV Mecel Volvo TU NIBE Industrier S-SENCE, Summary report 1995-2006 Table of contents Preface........................................................................................................................1 Executive summary....................................................................................................3 Sammanfattning .........................................................................................................5 1. 2. Introduction........................................................................................................7 Basic facts ..........................................................................................................7 2.1. Research groups and industrial partners ....................................................7 2.2. Financing..................................................................................................11 2.3. Organization.............................................................................................11 3. Key numbers ....................................................................................................13 3.1. Examinations............................................................................................13 3.2. Publications..............................................................................................13 3.3. International collaboration .......................................................................13 3.4. Mobility between the university and industrial partners..........................14 3.5. Commercialization and technology transfer ............................................14 4. Centre development .........................................................................................17 5. Technical and scientific achievements.............................................................21 5.1. Gas phase sensing ....................................................................................22 5.2. Liquid phase sensing................................................................................23 5.3. Biosensing................................................................................................24 5.4. Signal evaluation......................................................................................25 6. Industrial results and effects ............................................................................27 7. Final remarks ...................................................................................................29 Appendix A: Members of the board ........................................................................31 Appendix B: Examinations ......................................................................................33 Appendix C: Publications ........................................................................................39 Appendix D: IPR results ..........................................................................................59 S-SENCE, Summary report 1995-2006 2 S-SENCE, Summary report 1995-2006 Executive summary Sensor science has been a main activity at the Division of Applied Physics for 30 years. The division has during that time reached an internationally recognized position in the area. In order to further focus the research and to strengthen the bonds with Swedish industry, SSENCE was started in August 1995 and has since then attracted 25 industrial (or nonuniversity) partners. The centre was funded by NUTEK/VINNOVA, industrial partners and Linköping University in the Competence Centres Programme initiated by NUTEK and from 2001 managed by VINNOVA. After the last stage of the ten year program (ending June 30, 2006), S-SENCE is financed by the university, external grants and (new and old) industrial partners. The initially stated long-term goals of S-SENCE were to develop new applications of bio- and chemical sensors and sensor systems together with Swedish industry, and to keep a position as one of the internationally leading centres regarding bio- and chemical sensor science and development, goals which to a large extent have been fulfilled. The research within S-SENCE has been organized in three different sensor application areas (gas phase-, liquid phase- and biosensing) and one common project on sensor data evaluation techniques. During the ten year period the center has had activities in the following areas; cylinder specific monitoring and exhaust gas diagnosis of automotive engines, combustion and emission control by monitoring in flue gases from boilers, quality control and process monitoring in the food- and process industry, medical monitoring and diagnosis, environmental monitoring, water quality assessment, optimization of home appliances and biosensor technologies. The infrastructure of and the intellectual capital within S-SENCE have created a significant research and cooperation platform. The centre has built up a strong position within the university. SSENCE has for example contributed to multidisciplinary collaboration between different departments and faculties. S-SENCE has been organized in such a way that both generic and applied projects have been beneficial for the development of bio- and chemical sensors. Good examples of this are the development of the electronic tongue, a “high temperature SiC gas sensor” and new types of surfaces for affinity biosensors. Some of these results are already commercialized and one spin-off company, Senset, was formed during the ten year period. Furthermore, the research also formed the basis for a second spin-off company, SenSiC in 2007. The center has also been academically successful shown by the production of 165 papers published in refereed scientific journals and 177 international conference presentations. A significant part of these publications are joint publications with industrial partners. Personnel at the centre are often invited as speakers, in organizing committees for workshops and conference sessions, and as editors of scientific book chapters. In addition, since the start in 1995 S-SENCE has produced 21 PhD theses, 15 Licentiate theses and 53 Master theses. In addition there were 6 PhD students with S-SENCE by the end of the ten year program who have (or are expected to) become PhD's after 2006. All projects within S-SENCE have in general had a very intense international collaboration and the centre seems to be an attractive collaboration partner. Collaborations in various forms have existed with 8 Swedish and 24 international universities and 18 companies or research institutes not members of S-SENCE. In addition to this, S-SENCE is or has been involved in 8 EU projects (including more than 20 partners). S-SENCE has also had 15 visiting researchers during the years. In general, the industrial involvement in the projects has been very high and the influence of the industry on the strategic directions of the projects has been secured by intense participation in project meetings and the appointment of industrial chairmen’s in the projects. In total 52 persons were employed (partly or fully) by S-SENCE during the different stages and in addition approximately 80 persons at the industrial partners were involved in the S-SENCE activities. The personal mobility has been high. 7 PhD, trained 3 S-SENCE, Summary report 1995-2006 at the centre, 2 engineers and 4 M.Sc. from the centre have been employed by industrial partners. In addition one S-SENCE director has been employed as a research manager and two senior scientists and several PhD students have been part time employed by industrial partners. Furthermore, S-SENCE engineers have been engaged on an hourly basis for technology transfer and during periods of high workload. 2 senior scientists have also been members of research councils of the industrial partners. 21 patent applications have been filed of which 17 have at least one industrial partner as the applicant and 18 have at least one SSENCE researcher as inventor. 4 S-SENCE, Summary report 1995-2006 Sammanfattning Sensorvetenskap har under 30 år varit en huvudaktivitet vid avdelningen för Tillämpad Fysik, Linköpings universitet, och avdelningen har under den tiden nått en internationellt erkänd position inom området. För att fokusera forskningen och stärka banden med svenskt näringsliv startades S-SENCE i augusti 1995 och har sedan dess samarbetat med 25 olika företag. Satsningen finansierades av NUTEK/VINNOVA, industripartners och Linköpings universitet i det kompetenscentrumprogram som initierades av NUTEK och från 2001 leddes av VINNOVA. Efter sista etappen av det tioåriga kompetenscentrumprogrammet (som slutade 30 juni, 2006), finansieras S-SENCE av fakultetsmedel, externa anslag och (nya och gamla) industrikontakter. S-SENCE:s ursprungliga målsättning att utveckla nya tillämpningar av bio- och kemiska sensorer och sensorsystem med svensk industri och att försvara en position som ett av de internationellt ledande centrumbildningar inom bio- och kemisk sensorforskning och sensorutveckling har till stor del uppfyllts. Forskningen inom S-SENCE har varit organiserad i tre olika block: gasfas-, vätskefas- och biosensorapplikationer. Dessutom har en forskningsgrupp kring signalutvärdering funnits med. Centret har haft forskningsaktiviteter inom följande områden: cylinderspecifik övervakning och avgasdiagnostik av person- och lastbilsmotorer, förbrännings- och rökgasövervakning från förbränningspannor, kvalitetskontroll och processövervakning i livsmedels- och processindustrin, medicinsk övervakning och diagnos, miljöövervakning, vattenkvalitetsmätningar, optimering av vitvarumaskiner och utveckling av biosensorytor. S-SENCE infrastruktur och intellektuella kapital har skapat en betydande forsknings- och samarbetsplattform. Centret har byggt upp en stark position inom universitetet och har bland annat bidragit till multidisciplinärt samarbete mellan institutioner och fakulteter. Genom S-SENCEs struktur har både generiska och tillämpade projekt bidragit till utvecklingen av bio- och kemiska sensorer. Bra exempel på detta är utvecklingen av en elektronisk tunga, en högtemperatur SiC gassensor och nya ytor för affinitetsbaserade biosensorer. En del av dessa resultat har redan kommersialiserats och ett avknoppningsföretag (Senset) bildades under perioden baserat på forskningen kring den elektroniska tungan. Dessutom ledde forskningen kring kiselkarbidbaserade högtemperatursensorer till att ytterligare ett avknoppningsföretag, SenSiC, bildades 2007. Centret har också varit framgångsrikt ur en akademisk synvinkel. Detta illustreras av produktionen av vetenskapliga artiklar där man sedan starten har publicerat 165 artiklar i vetenskapliga tidskrifter och bidragit till 177 internationella konferenspresentationer. Industripartners är medförfattare till en stor del av dessa vetenskapliga arbeten. Personal inom S-SENCE är ofta inbjudna som talare på konferenser, medlemmar i organisationskommittéer för workshops och konferenssessioner samt författare av vetenskapliga bokkapitel. Sedan starten har S-SENCE producerat 21 doktorer, 15 licentiander och 53 examensarbeten. Dessutom var 6 doktorander aktiva vid utgången av tioårsprogrammet, vilka senare har disputerat eller förväntas disputera vid S-SENCE. Alla S-SENCE projekt har generellt sett haft ett mycket intensivt internationellt samarbete och centret verkar vara en attraktiv samarbetspartner. Samarbete i olika former har ägt rum med 8 svenska och 24 internationella universitet samt 18 företag eller forskningsinstitut utöver S-SENCE medlemsföretag. S-SENCE har varit partner i 8 EU-projekt (inkluderande över 20 partner). Under åren har S-SENCE haft 15 gästforskare. Generellt har industriengagemanget i projekten varit mycket högt och företagens inflytande på projektens framåtskridande och inriktning har säkerställts av företagsrepresentanternas deltagande i projektmöten och av att varje projektområde har haft en industriell ordförande. Totalt var 52 personer anställda (helt eller delvis) av S-SENCE i verksamheten och dessutom har ca. 80 personer från företagen varit involverade i S-SENCE arbete. Den personella rörligheten 5 S-SENCE, Summary report 1995-2006 mellan universitetet och företagen har generellt varit hög och totalt har 7 doktorer utbildade inom centret, 2 tekniker och 4 civilingenjörer fått anställning hos S-SENCE industripartners. Dessutom har en föreståndare blivit forskningschef, två seniora forskare och flera doktorander varit deltidsanställda och ingenjörer anställda på timbasis hos industripartners. 2 seniora forskare har dessutom suttit med i forskningsråd hos industripartners. 21 patentansökningar har lämnats in av vilka 17 har minst en industripartner som sökande och 18 har minst en SSENCE-forskare som uppfinnare. 6 S-SENCE, Summary report 1995-2006 1. Introduction At the research division Applied Physics at Linköping University (LiU), research has been conducted in the field of chemical sensors, especially so-called catalytic MOSFET (metal-oxide-semiconductor field-effect transistor) sensors, since roughly 1978. The work has resulted in sensors for a large number of chemical compounds. The sensors have been used successfully in applications of so-called electronic noses, which consist of arrays of chemical sensors where response patterns are evaluated by various pattern recognition techniques. Lately, also measurement systems suitable for aqueous solutions, so called electronic tongues have been developed. In 1995 the Centre of excellence S-SENCE, the Swedish Sensor Centre, was established at LiU with the main task to further develop and evaluate bio- and chemical sensors and sensor systems for industrial applications. The research of S-SENCE falls within the area of bio- and chemical sensors and sensor systems. In this area S-SENCE competence profile ranges from scientific expertise in sensor science, surface science and catalysis, bio-molecular interactions, microbiology, signal processing and multivariate analysis, electronic components and device fabrication. Through industrial contacts, competence in all application areas can be found, ranging from combustion emission monitoring over pulp and paper processes, dishwashers and washing machines, detection of explosives and biomolecules, to drinking water production. The ten year program was divided in four stages: Stage 1: August 1995 – 1997, Stage 2: 1998 – 2000, Stage 3: 2001 – 2003 and Stage 4: 2005 – June 2006. Each stage had its own budget and combination of industrial partners as presented below. 2. Basic facts 2.1. Research groups and industrial partners 2.1.1. Departments and research groups at Linköping University The centre has been hosted at the Department of Physics, Chemistry and Biology (IFM) at Linköping University (the Department changed name from Physics and Measurement Technology during stage IV, but kept the acronym IFM). The number of employees at the department is around 330, including 40 full professors and some 130 graduate students. In addition approximately 100 guest researchers visit the department every year resulting in a total number of over 400 researchers. The department is organized in 5 Scientific Areas: Applied Physics, Biology, Chemistry, Material Physics and Theory and Modelling. The centre has been run in close collaboration with the multidisciplinary Scientific area Applied Physics. This is reflected in that the members of the Scientific area (and the centre) are electrical engineers, physicists, chemists, biochemists and biologists and that the projects are chosen in the areas between physics and chemistry, and physics and biology. The different research areas in Applied Physics are biomaterials, biomolecular and organic electronics, sensor science and molecular physics, scanning 7 S-SENCE, Summary report 1995-2006 probe microscopy, biotechnology, catalytic reactions, and applied optics. S-SENCE is or has been doing research together with scientists in almost all of these research areas. S-SENCE also has extensive collaboration with the division of Chemistry, the division of Biology, and the division of Material Physics at IFM. These collaborations are mainly performed in the form of master theses on research that is relevant for SSENCE and its partners. During stage II collaboration with the Department of Electrical Engineering (ISY) was established through a joint PhD-student. This department is divided into 9 divisions and has 160 employees. The collaboration was extended during the last part of stage III, when a joint generic project between one of the project leaders at SSENCE and a professor at ISY started. This collaboration continued during stage IV. 2.1.2. Research staff A large number of persons have been involved in the activities of S SENCE during the four stages of S-SENCE as illustrated by Table 1: 8 S-SENCE, Summary report 1995-2006 Table 1. Personnel during the four stages of S-SENCE Stage 1 Aug 1995 1997 S-SENCE personnel Professors and Senior scientists Ingemar Lundström Per Mårtensson Anita Lloyd Spetz Carl-Fredrik Mandenius Fredrik Winquist Hans Sundgren Amir Baranzahi Martin Holmberg Lars-Gunnar Ekedahl Tina Krantz-Rülcker Bo Liedberg Mats Eriksson Pentti Tengvall Eva Hedborg Sissel Jacobsen Helen Dannetun Trine Platau Vikinge Robert Bjorklund Graduate students employed by LiU Amir Baranzahi Eva Hedborg Martin Holmberg Tomas Eklöv Peter Tobias Thomas Bachinger Kenny Hansson Mikael Löfdahl Susanne Holmin Henrik Svenningstorp Lars Unéus Anna Elisabeth Åbom Tom Artursson Ye Zhou Anette Salomonsson Charlotte Söderström Jenny Carlsson Helena Wingbrant Roger Klingvall Mike Andersson Henrik Peterson John Olsson Christian Ulrich Graduate students employed by industrial partners Patrik Ivarsson Håkan Johnson Anders Carlsson Britt-Inger Ljungberg-Willing Torgny Ljungberg Gunnar Forsgren Research engineers Per-Erik Fägerman Martin Einehag Ingemar Grahn Evald Mildh Björn Widén Marcus Andersson Ellinor Rydberg Christian Ulrich Administrative assistants Carin Jonsson Therese Dannetun Marie Urbán Pia Blomstedt Susann Årnfelt. Stage 2 1998-2000 Stage 3 2001-2003 Stage 4 2004 June 2006 9 S-SENCE, Summary report 1995-2006 2.1.3. Industrial partners During the four stages of the ten year program 25 industrial partners were engaged in S-SENCE. Different partners were engaged during the different stages according to Table 2: Table 2. Industrial partners during the four stages of S-SENCE. (NST changed name to AppliedSensor after a merger with MoTech GmbH, Germany, in 2000). Partner AppliedSensor (form. NST) Asko Cylinda Assi Domän Carton Biacore BiosensorApplications Billerud Duni/Finess Eka Chemicals Ford GHI Iggesund Paperboard Mecel NIBE Otre Pharmacia & Upjohn Senset SKL SLR StoraEnso Tekniska Verken Tetra Pak Vattenfall Volvo TU Volvo PV Volvo Powertrain Stage 1 Aug 1995 1997 Stage 2 1998-2000 Stage 3 2001-2003 Stage 4 2004 June 2006 10 S-SENCE, Summary report 1995-2006 2.2. Financing The financing of S-SENCE during the whole program is shown in Table 3. The funding is shown both in total and for each stage. The contributions from the industrial partners are divided in cash contributions and in kind contributions. Table 3. Financing of S-SENCE during the four stages 1995-2006 Stage 1 Aug 1995 - 1997 Cash Partner In kind AppliedSensor (form. NST)** Stage 2 1998 - 2000 Cash Stage 3 2001 - 2003 In kind Cash Stage 4 2004 - June 2006 In kind Cash In kind Total Cash Cash + In kind In kind 1 050 1 449 1 575 846 700 665 3 325 2 960 Asko Cylinda 450 1 286 600 2 262 400 350 1 450 3 898 5 348 Assi Domän Carton 450 1 804 300 991 750 2 795 3 545 0 542 850 1 269 3 274 Biacore 6 285 100 513 950 2 324 BiosensorApplications** 300 1 200 300 1 200 1 500 Billerud 400 799 400 799 1 199 712 2 713 3 425 400 100 500 800 1 200 2 000 Duni/Finess 450 Eka Chemicals 400 1 894 262 819 100 Ford* 800 GHI 250 1 200 300 943 550 1 360 1 910 Iggesund Paperboard 300 842 600 458 417 900 1 300 2 200 Mecel 300 569 350 1 278 650 1 847 2 497 400 476 876 750 1 908 2 658 NIBE 400 Otre 750 Pharmacia & Upjohn 1 500 900 1 908 474 Senset 200 SKL 476 837 720 SLR 400 772 200 1 291 StoraEnso 300 1 048 600 825 350 1 012 2 432 425 441 866 807 1 500 1 156 2 656 VINNOVA (NUTEK) 6 800 Linköping universitet 258 4 790 4 910 External grants 616 650 2 367 3 017 600 600 600 1 200 600 1 200 600 1 200 1 800 13 605 7 262 11 648 4 400 7 750 21 462 37 793 59 255 18 000 0 18 000 0 12 000 1 692 13 229 50 12 841 1 000 6 300 8 400 7 076 Pilot projects etc. Total 10 353 1 513 1 430 10 558 Total Cash + In kind 510 0 Volvo Powertrain** 3 500 500 600 Volvo PV Total partners 20 258 9 700 720 2 663 441 900 739 720 2 063 2 773 425 300 0 600 1 182 Tetra Pak Volvo TU 1 037 1 873 672 349 2 874 837 900 750 600 474 200 1 250 Tekniska Verken Vattenfall 2 400 34 392 61 226 26 834 33 818 58 307 24 489 18 913 18 103 37 016 54 800 0 54 800 3 000 41 333 44 333 16 989 0 16 989 1 430 0 1 430 97 681 79 126 176 807 176 807 * In kind not specified, contribution as in contract ** In kind not specified for 2005/2006, contribution as in contract 2.3. Organization 2.3.1. Board of directors According to the main contract governing the activities of Competence Centres, SSENCE has had a board of directors that approves the Operating plan for each stage as well as the yearly budget for the centre. The board has been very engaged in the work and has met 3-4 times every year. Initially the board was appointed for the same 11 S-SENCE, Summary report 1995-2006 period as the stages (stages I and II). During stages III and IV, however, the period of appointment of the board was changed such that the same board would be active during the stage transition in 2003-2004. The five boards active during the ten year program are given in Appendix A. 2.3.2. Directors of S-SENCE The director of S-SENCE was responsible for the operational management of the activity and reported to the Board of Directors. The directors of S-SENCE have been • Per Mårtensson, August 1995 – fall 1998 • Lars-Gunnar Ekedahl, Nov. 1998 – May 2002 • Tina Krantz-Rülcker, May 2002 – June 2006 Per Mårtensson was recruited by NST as director of R&D in 1998 and Lars-Gunnar Ekedahl entered a position as vice-chancellor (president) of Högskolan Väst (formerly Högskolan i Trollhättan/Uddevalla) in 2002. 2.3.3. Research secretaries In 1998 a new position as "Research secretary" was created in order to assist the director. The research secretaries have been: • Tina Krantz-Rülcker, Dec. 1998 – April 2002 • Mats Eriksson, May 2002 – June 2006 2.3.4. Scientific and industrial advisory board A scientific and industrial advisory board was initiated during 2002. It consisted of: • Prof. Nico de Rooij, Institute of Microtechnology, University of Neuchâtel, Switzerland (Scientific expert) • Prof. Elena Dominguez, University of Alcala, Madrid, Spain (Scientific expert) • Mr. Sven-Bertil Nilsson (Industrial expert) 12 S-SENCE, Summary report 1995-2006 3. Key numbers Below we give key numbers for various activities financed within S-SENCE. 3.1. Examinations In total 21 PhD, 15 Licentiate degrees and 53 Master theses have been awarded for work related to S-SENCE since its start, according to Table 4: Table 4. Examinations at S-SENCE 1995-2006. Type of examination Stage 1 Stage 2 Stage 3 Stage 4 Total PhD 3 6 9 3 21 Lic. 0 10 2 3 15 Master 2 20 16 15 53 Appendix B lists the names of all persons who were awarded degrees and performed master theses throughout stages I-IV. In addition there were 6 PhD students with SSENCE by the end of stage IV who have (or are expected to) become PhD's after stage IV of S-SENCE. 3.2. Publications In total S-SENCE related work has resulted in 165 publications in refereed journals and 177 conference contributions: Table 5. Publications at S-SENCE 1995-2006. Stage 1 Stage 2 Stage 3 Stage 4 Total Articles in refereed journals 25 51 49 40 165 Conference contributions 31 61 44 41 177 In Appendix C the full publication list is presented. 3.3. International collaboration • S-SENCE personnel have been involved in 8 EU-projects. • Approximately 25 foreign university research groups have had collaboration with researchers within S-SENCE • S-SENCE has hosted 21 guest researchers for periods exceeding 1 month. 13 S-SENCE, Summary report 1995-2006 3.4. Mobility between the university and industrial partners Below are the numbers of personnel exchange between the industry and the university listed: • The director of S-SENCE Per Mårtensson was employed by Nordic Sensor Technologies in 1998 as a director of R&D. • 2 senior researchers and project leaders at S-SENCE, Prof. Anita Lloyd Spetz and Dr. Mats Eriksson, have been employed part time by AppliedSensor. • 3 industrial graduate students employed by Asko Cylinda, AssiDomän, and DuniFiness. • 4 PhD’s were employed by NST/AppliedSensor. • 1 PhD and 1 Licentiate employed by Volvo TU. • 3 PhD’s have worked part time at AppliedSensor during their PhD studies. • 1 PhD was employed by Otre • 2 engineers were employed by AppliedSensor. • 1 Diploma worker was employed by Mecel. • 1 Diploma worker was employed by Otre • 1 Diploma worker was employed by AppliedSensor • Dr. Anders Brundin at Iggesund, has obtained a “docentur” at LiU. He has, furthermore, been involved both in graduate and undergraduate teaching. • Prof. Ingemar Lundström and Dr. Tina Krantz-Rülcker have been members of the research councils of Otre and Asko Cylinda, respectively. 3.5. Commercialization and technology transfer • In total S-SENCE has produced 21 patents or patent applications, see Appendix D and Table 6: Table 6. Patent applications at S-SENCE 1995-2006. Patent applications Stage 1 Stage 2 Stage 3 Stage 4 Total 5 8 7 1 21 Some examples of commercialization and technology transfer (see also chapter 6): • The voltammetric electronic tongue research and development within S-SENCE during stage I led to the formation of a spin-off company, Senset AB, in 2001 by researchers Fredrik Winquist, Tina Krantz-Rülcker, Lars-Gunnar Ekedahl and Ingemar Lundström. The electronic tongue technology was commercialized by Senset during stages III and IV. • The collaboration with NIBE in stage IV led to the formation of a spin-off company, SensiC AB, launched in 2007 by researchers Prof. Anita Lloyd Spetz 14 S-SENCE, Summary report 1995-2006 and Dr. Mike Andersson together with two entrepreneurs, Bo Hammarlund and Lars Hammarlund, with NIBE as the first customer. SenSiC is now commercializing SiC sensors e.g. for NIBE and other domestic boiler manufacturers and as an oxygen sensor for the automotive industry. • In 2004 it was reported that the SiC based NH3 sensor successfully detected 10 ppm NH3 in diesel exhausts. It was taken as proof of concept by AppliedSensor and technology transfer was performed for the application control of SCR in diesel trucks. The SCR, Selective Catalytic Converter, process means that NOx is reduced in the catalytic converter by NH3, which is injected as urea in the exhaust system. Technology transfer was performed by Prof. Anita Lloyd Spetz and the PhD student Helena Wingbrant, both hired part time by the company. The commercialization of the SiC based NH3 sensor was, however, stopped in the company in 2006. The SiC based sensors are now commercialized by SenSiC • In 2007 it was announced that AppliedSensor’s hydrogen gas detection module is incorporated in the BMW Hydrogen 7, which was the first hydrogen driven car in the luxury performance segment. The connection between AppliedSensor and BMW was initiated by Dr. Mats Eriksson during a period as a visiting scientist in Munich 2002. The development was then carried out at AppliedSensor, including former employees at S-SENCE employed by AppliedSensor, in collaboration with BMW. 15 S-SENCE, Summary report 1995-2006 16 S-SENCE, Summary report 1995-2006 4. Centre development The original long-term goals of S-SENCE were to develop new applications of bioand chemical sensors and sensor systems together with Swedish industry, and to keep a position as one of the internationally leading centres regarding bio- and chemical sensor development. The strong infrastructure as well as the human capital that has been built up by S-SENCE has created a significant intellectual capital that we regard as an obvious proof of progress of the centre since its start. There were no major changes in the organisation of the centre since it started. However, since there was a change in industrial partners between the stages (see section 2.1.3) and the centre increased its activities during the stages the number of different applications also increased. On the other hand, since some industrial partners withdrew their membership some applications (projects) also ended between stages. In each of the different application project areas industrial contact persons from all partners were identified and participated in the project meetings, held at least four times per year. Beside these project area meetings, additional project meetings were frequently held with the individual companies to discuss specific issues related to each application. In most of these meetings the groups performing basic studies were participating resulting in a close contact and direct distribution of more basic results to the industrial partners. The number of publications produced in the centre with authors both from the university and the industry is also a good example on how the industry has taken an active role in the scientific research. For each of the application project areas an industrial project leader and a project leader at the university were identified. Also, the PhD students at S-SENCE have had an identified co-supervisor from industry. This way of organising the project groups led to a very strong industrial influence on the directions of the research. Beside the project meetings information was distributed to all industrial partners in form of minutes from the weekly meetings where presentations, discussions of questions of mutual interest ranging from administrative routines to technical support, scientific questions and collaborations were held. The S-SENCE days, held every year, where all members of the Centre gathered, were also important occasions when the research groups as well as industrial partners met to discuss results and future strategies in the projects. Internet naturally also played an important role as a medium for information spreading and exchange. During stage II a new type of projects were introduced. These projects had the nature of pilot projects to test ideas and measurement techniques in different applications. This was in line with the initial thoughts that S-SENCE would run an “Application lab” where specific ideas could be tested and short pilot projects could be run. We experienced this as a very good way of introducing new partners into S-SENCE and as the result of pilot projects run during stage II 3 new partners (Otre AB, Tekniska Verken AB and Tetra Pak AB) joined the centre for stage III and Tekniska Verken also continued as a partner in stage IV. During stage III pilot projects, as well as one longer project on a bilateral basis, were also performed. One of the pilot projects resulted in a new partner (Billerud) also in stage IV. One recommendation that was given as a result of the first evaluation of the centre was that the centre needed to establish a broader academic base. During stage II this 17 S-SENCE, Summary report 1995-2006 recommendation was met by initiating two more generic projects on the most crucial basic research needed in the centre. One dealt with the long-term stability of our gas sensors based on the field effect and the other concerned data analysis, calibration routines and drift compensation. The broadening of the academic base was further improved during stage III when one generic project area was connected to each of the three application project areas (gas sensor research, basic studies of the electronic tongue and research on biospecific interactions, see figure 1 in section 5) in addition to the data evaluation project area. During stage III discussions with the president of the university took place and the possibilities and advantages of developing a centre independent of the Department of Physics and Measurement Technology were thoroughly evaluated. However due to the boundary conditions the conclusion was that there were still benefits with the association to the department compared to a self standing unit in the university organisation. A Scientific and Industrial advisory board was initiated during stage III. The centre had two meetings with this board that consisted of Prof. Nico de Rooij, Institute of Microtechnology, University of Neuchâtel, Switzerland and Prof. Elena Dominguez, University of Alcala, Madrid, Spain, as scientific experts and Mr. Sven-Bertil Nilsson as the industrial expert. A plan describing how to tackle the issues of how to include new partners and projects at the start of a new stage as well as during a stage, implementation of results, new sources of funding, etc. was discussed during stage II and established during stage III. The more specific goals of S-SENCE, as expressed in the original proposal to NUTEK, are formulated in points below. Under each point short examples are given illustrating how the goals have been met and fulfilled. The statements are in some cases further expressed under other headings in this report. The initial goals of SSENCE were: 1. Set up cooperation with industry and other external partners regarding the development, production and application of sensors and sensor systems During the 10 years of operation the centre has collaborated on the development and application of sensor science with 25 industrial (or non-university) partners. In most cases all actors along the whole chain (development, production, application) has been possible to realize, but in some cases, in particular where a sensor manufacturer with mass production capacity has been a prerequisite, this actor has been impossible to incorporate. 2. Increase personnel- and information exchange with external partners The personnel exchange has been rather extensive since the start of the centre with more than 20 persons leaving the centre for employments in the industry. Information exchange between the centre and the partners as well as between various industrial partners has been facilitated by active industrial representation in the project management and execution. The distribution of the minutes from the weekly meetings at the university in the centre, the yearly two-days “S-SENCE meeting” when the whole centre meets, the industry normally well represented, to inform on new results 18 S-SENCE, Summary report 1995-2006 and discuss future activities are other examples of how information has been delivered and exchanged. 3. Perform basic research of interest to several types of industries Each of the different application project areas have in general had more than one (and up to seven) industrial partner, from different industrial branches e.g. car producer and power supplier, involved in the collaboration. These application projects were then backed up by generic activities as described above. By organizing the research in this way the different companies all got access and benefit of the basic research. 4. Develop new technologies for sensors and sensor systems As a result of the basic research performed during stage I of the centre the electronic tongue was developed. This field of research attracted during stage II three new industrial partners to the centre and at the start of stage III this number had increased to seven new industrial partners. 5. Obtain new knowledge to be used for new technology during the next decade See point 3 and 4. 6. Coordinate basic research of importance for the development of bio- and chemical sensors The way of organising the generic and applied research within S-SENCE has been an attempt to coordinate the basic research conducted by the centre in a way so it would be beneficial for the development of bio- and chemical sensors. Examples of how this has been successful are for example the development of the electronic tongue; a “high temperature SiC sensor” has opened further application areas such as combustion emission monitoring as well as providing a further increase in selectivity patterns. 7. Make it possible to start or develop cooperation with other research groups or disciplines of importance for the development of sensors and sensor systems Intense cooperation within all projects with different research groups at Swedish as well as international universities and institutes has been a natural part of the work. 8. Offer a platform for the start of spin-off companies Three spin-off companies have been the result of the activities in, or the personnel from, the centre. In one case, Mandalon, the build up of knowledge and know-how of personnel in the centre led to the start of a company. In the two other cases, Senset and SenSiC, it was a direct result of the research conducted in the centre that initiated the start of the companies (see section 5.1-2). 9. Deepen international contacts/cooperation and to become a basis for research within EU-programs All projects within S-SENCE have had a very intense international net of contacts. Collaborations in various forms exist with universities all over the world and companies or research institutes not members in S-SENCE. In addition to this, SSENCE has been involved in 8 EU-projects. The conclusion is that all of the goals expressed above have been met to various degrees. 19 S-SENCE, Summary report 1995-2006 20 S-SENCE, Summary report 1995-2006 5. Technical and scientific achievements As indicated above, the organization of the projects within S-SENCE changed from a number of very specific application areas to three very broad project areas (gas phase sensing, liquid phase sensing and biosensing). The latter division was used during stages III and IV and is illustrated in Fig. 1. An industrial partner could join one or several project areas and participate in one or several projects within each project area. For each project area there has also been basic research activities supporting the applications of each sensor technology. In addition to the three project areas there was furthermore a generic group on signal evaluation, supporting all the three project areas. In general, the activity has been high within all project areas. In sections 5.1 – 5.4 the progress in the different areas is presented in some detail. S-SENCE Tina Krantz-Rülcker, Director Gas phase Applications Liquid phase Applications Biosensor Applications Anita Lloyd Spetz Tina Krantz-Rülcker Fredrik Winquist Bo Liedberg AppliedSensor Ford Motor Company NIBE Volvo Powertrain Basic gas sensor research Mats Eriksson Anita Lloyd Spetz Asko Cylinda Billerud Ford Motor Company Senset Tekniska verken Volvo Powertrain Biacore Biosensor Applications Biospec. interact. research Bo Liedberg Basic gas sensor research Fredrik Winquist Signal evaluation Martin Holmberg Fig. 1. Overview of the research organization at S-SENCE during stages III and IV and the distribution of the participating member companies during stage IV. 21 S-SENCE, Summary report 1995-2006 5.1. Gas phase sensing A few highlights of the activities in the gas sensor area are: • A silicon carbide based sensor system was developed together with NIBE Industry for control of domestic boilers. The sensor system, which also included a commercial temperature sensor, was used to control the primary and secondary air inlet of the wood fueled boiler. The combustion efficiency increased considerably and the emissions were drastically lowered. Both rather wet wood and very dry wood could be used as fuel, still with good result. This sensor system was later further developed by a spin-off company (SenSiC AB, launched in 2007) for commercialization. • Already in stage I it was shown that SiC based gas sensors can be operated at 750 °C for several weeks and show time constants below a few milliseconds. These properties facilitated cylinder-specific monitoring at tests on the exhaust gases from real engines. • SiC-FET ammonia sensors were successfully tested on two Volvo trucks during a 10 days excursion in Spain. The two trucks were equipped with urea injection systems in order to reduce the nitrogen oxide emissions. • AppliedSensor carried out development on a hydrogen sensor for safety applications in the automotive segment. In 2007 it was announced that AppliedSensor’s hydrogen gas detection module is incorporated in the BMW Hydrogen 7 which was the first hydrogen driven car in the luxury performance segment. The connection between AppliedSensor and BMW was initiated by Dr. Mats Eriksson during a period as a visiting scientist in Munich 2002. The development was then carried out at AppliedSensor, including former employees at LiU/S-SENCE employed by AppliedSensor, in collaboration with BMW. In stages I and II the gas phase sensor work was divided into applications based on the electronic nose and high temperature applications based on the MISiC sensor. An electronic nose is an array of non-selective gas sensors with partly overlapping selectivities, combined with multivariate sensor signal analysis. MISiC stands for Metal-Insulator-Silicon Carbide, i.e. a Metal-Insulator-Semiconductor (MIS) field effect device where the semiconductor is made of silicon carbide (SiC). These devices can be operated in the temperature region 100 – 800 °C, which is a much wider range than that of MIS field effect devices based on silicon. In stages III and IV the idea of the electronic nose as a general instrument applicable in all kinds of applications was somewhat downplayed in favor of smaller and more applications specific sensor systems. The high temperature work on MISiC sensors were initially focused on cylinder specific monitoring of automotive engine exhausts. Later on projects on ""Flue gas monitoring", "Cold start lambda sensor", "NH3 sensor for SCR control" along with "Characterization of MISiC sensors" and "Prototype sensor system for boiler control" were important. Examples of project areas exploring the applicability of the electronic nose are "Field methods for breath alcohol measurements", "Bioprocess measurement with multi sensor arrays" and "New methods for product quality control". In the latter case the 22 S-SENCE, Summary report 1995-2006 applicability to measurements on quality parameters on cereals, paper products, milk and food were investigated. Later on (stages II-IV) more basic research on hydrogen and ammonia sensors was carried out. The results from these studies gave new insights to the gas response mechanisms of the sensors, both for the Si and the SiC based devices. This new knowledge concerns gas adsorption on the metal and the insulator surfaces, the catalytic reactions occurring at the metal-gas interface and the properties of the metalinsulator interface. 5.2. Liquid phase sensing A few highlights of the activities in the liquid phase sensing area are: • The voltammetric electronic tongue was commercialized by the company Senset AB during stages III and IV. A method for the determination of the environmentally important parameter chemical oxygen demand (COD) was developed during stage IV, and on-line analytical systems were installed in the paper and pulp industry at the S-SENCE partner Billerud. These systems have proven very reliable, with a minimum of maintenance. • An electronic tongue was implemented in the product line in a dairy industry (Skånemejerier). The electronic tongue could follow milk qualities, change of milk sources, and cleaning efficiency for over six months without any need of service. • A method for monitoring water quality at a water production plant of Tekniska Verken was introduced. Successful measurements of the water quality have been performed. Also, an automatic sample handling system has been developed and run during four months. The aim of the project area has been to obtain a deeper knowledge of the measurements principles of a new sensor technology, an electronic tongue, for measurements in liquid phases, and to utilize this technology in relevant applications. The voltammetric electronic tongue developed was a very new and unproven concept when the second stage of the center and the project area started. The applicability and versatility of the concept was therefore uncertain but intriguing. Through the results obtained from all the projects the potential of the concept was shown to be very high. Successful measurements have thus been performed on a range of samples such as milk, yogurt, white water, pulp, dish and washing machine processes, fermentation processes, fruit juices, jam, water etc with different issues for each category. During stage III, implementation of the technique was performed in a dairy industry for measurements of mixed product phases as well as for the monitoring of dish processes. Interesting results were also obtained on soil; both pH and the concentration of cadmium, copper, and some more environmentally interesting heavy metals could be determined. The studies of the combination of various electronic senses like for example electronic noses and electronic tongues have also been very successful and showed 23 S-SENCE, Summary report 1995-2006 that more information will be gained by such a combination. In an experiment for quality studies on different types of red wine, an electronic nose, an electronic tongue, a color meter, a conductivity meter and a pH electrode were successfully used, each sensor system giving specific information. The most important objectives of the project have been: • Basic development and optimization of the electronic tongue for different applications. This includes development of reference methods, studies of different pulse techniques and drift studies. • New methods for control of microbial activity in whitewater and pulp systems. Development of sampling and sample handling in pulp system. Time series. • Optimization of dish and washing processes by the use of electronic noses and electronic tongues. • Detection of microbial activity in food with an electronic tongue. Development of measurement procedures of fungal growth, measurements of fungal growth during various growth stages. • Monitoring of product changes in the dairy industry by using an electronic tongue. Development of an electronic tongue applicable in a food production process with high hygienic status. • Monitoring of water quality by using an electronic tongue. • Monitoring of dishing efficiency in a dairy industry. Development of a robust and hygienic electronic tongue for use in the dairy industry • Monitoring of ozone concentration in a sterilization unit. Development of ozone prediction algorithms from electronic tongue data. 5.3. Biosensing A few highlights of the activities in the biosensing area are: • New types of biosensor surfaces have been developed both for Biacore and Biosensor Applications. The detection of small molecules, explosives and narcotics, was successfully demonstrated using imaging surface plasmon resonance and selective immobilized antibodies. Discrimination of different drugs in a mixture (heroin, ecstasy, cocaine, ...) was obtained. • Coagulation could for the first time be detected under flow conditions by the surface plasmon resonance (SPR) technique • Piezo-dispensed microarrays of multivalent chelating thiols for protein-protein interaction studies • Gold nano-particle based bioassays for the detection of immunocomplex formation • Multisensing surfaces through photografted poly (ethylene glycol) with excellent non-fouling properties for biosensing applications (microarrays, gradients, ...) In this project area the work has been focused on biosensors where a biological interaction is transformed into a measurable signal. During stage III recent developments in the area of soft lithography (so-called micro contact printing, μCP) were utilized for the generation of novel microarray sensing chips for bio- and chemical sensor applications. One of the important goals was to create a prototype chip that can be integrated with the present detection and liquid handling systems of 24 S-SENCE, Summary report 1995-2006 the Biacore instruments. The production of hydrophobic barriers on the already existing Biacore biosensor chip was presented. These barriers are intended to hold nanoliter-picoliter volumes of the solutions in place during biological activation of the chip. During stage IV the collaboration with Biacore focused on the assembly of a new instrument for real time imaging of biospecific interaction phenomena at surfaces. We have also worked on the design and production of a fluidic system that is compatible with simultaneous SPR and fluorescence detection. BAAB is developing technology for collection, enrichment and detection of explosive substances and narcotics. The detection is performed with a QCM transducer that consists of thin gold film on top a quartz crystal. The work includes the development of new or improved surface chemistry that enhances the sensitivity and selectivity of their biosensing system. During stage II of S-SENCE a project on blood coagulation was run together with Biacore and GHI. The background was that blood factor deficiencies as well as medical drugs affect the blood coagulation time and kinetics. The real-time observation of blood interaction with sensor surfaces modified in an appropriate and controlled way may reveal the blood status in an early phase. The brief sample preparation time increases the potential of the method in bed-side applications. The main aim was to improve analysis and diagnosis of blood at flow conditions instead of the present steady-state analysis. Some of the achievements were that coagulation was for the first time detected under flow conditions by SPR and that blood plasma was studied and downstream coagulation due to upstream surface-bound procoagulant (thromboplastin) was observed. 5.4. Signal evaluation A few highlights of the activities in the signal evaluation group are: • Development of a new method for drift counteraction called component correction. The method is based on standard multivariate techniques modified to suit chemical sensor systems. • Extensive study of the information content in electronic tongue signals. This also led to the development of a curve-fitting method to compress data. • Development of a wavelet-based algorithm for compression of data from the electronic tongue. • Development of a new drift counteraction method based on multiple calibration substances. • A sensor data evaluation method for monitoring of flue gases in heaters has been developed. The method shows that it is possible to use the high temperature sensors in small household heaters in order to improve the performance. The method also constitutes a foundation for developing models for control of the heater. The signal evaluation group in S-SENCE has worked with multivariate analysis and pattern recognition aspects of sensor arrays, that is, to develop new techniques that better utilize the information from the sensor arrays. In this work, data from both the electronic nose, gas sensor arrays and the electronic tongue have been used. The focus has been on developing new algorithms and adapting existing algorithms to suit the 25 S-SENCE, Summary report 1995-2006 needs of all groups in S-SENCE. The aim has been to work with a whole chain of tasks: Problem Identification; Development/study of algorithms; Adaptation to our needs; Evaluation of its performance with real data from the electronic nose or tongue. 26 S-SENCE, Summary report 1995-2006 6. Industrial results and effects The Competence Centre for Catalysis, KCK, developed a model on how to handle IPR-issues that became the model for most competence centres. In short, the message in this model is that the inventor/-s owns their invention with a royalty-free right of use for the industrial partners. These partners also have an option to acquire the ownership of the patents according to specified conditions. 21 patent applications have been filed (see Appendix D) of which 17 have at least one industrial partner as the applicant and 18 have at least one S-SENCE researcher as inventor, illustrating the strong collaborative spirit between academia and industry during the whole 10 year period. The personal mobility has been high. 7 PhD, trained at the centre, 2 engineers and 4 M.Sc. from the centre have been employed by industrial partners. In addition one SSENCE director has been employed as a research manager, two senior scientists have been part time employed by industrial partners and S-SENCE PhD students and engineers have been engaged on an hourly basis for technology transfer and during periods of high workload. 2 senior scientists have also been members of research councils of the industrial partners. The voltammetric electronic tongue, developed within S-SENCE during stage I led to the foundation of a spin-off company, Senset AB, in 2001 by researchers Fredrik Winquist, Tina Krantz-Rülcker, Lars-Gunnar Ekedahl and Ingemar Lundström. The commercialization led to a method for the determination of the environmentally important parameter chemical oxygen demand (COD) which was developed during stage IV, and on-line analytical systems were installed in the paper and pulp industry, e.g. at the S-SENCE partner Billerud. These systems have proven very reliable, with a minimum of maintenance. A silicon carbide based sensor system was developed together with NIBE industrier for control of domestic boilers. The sensor system, which also included a commercial temperature sensor, was used to control the primary and secondary air inlet of the wood fueled boiler. The combustion efficiency increased considerably and the emissions were drastically lowered. Both rather wet wood and very dry wood could be used as fuel, still with good result. The project led to the formation of a spin-off company, SenSiC AB, launched in 2007 by researchers Anita Lloyd Spetz and Mike Andersson together with two entrepreneurs, Bo Hammarlund and Lars Hammarlund, with NIBE as the first customer. SenSiC is now commercializing SiC sensors e.g. for NIBE and other domestic boiler manufacturers and as an oxygen sensor for the automotive industry. In 2004 it was reported that the SiC based NH3 sensor successfully detected 10 ppm NH3 in diesel exhausts. It was taken as proof of concept by AppliedSensor and technology transfer was performed for the application control of SCR in diesel trucks. The SCR, Selective Catalytic Converter, process means that NOx is reduced in the catalytic converter by NH3, which is injected as urea in the exhaust system. Technology transfer was performed by Prof. Anita Lloyd Spetz and the PhD student Helena Wingbrant, both hired part time by the company. The commercialization of 27 S-SENCE, Summary report 1995-2006 the SiC based NH3 sensor was, however, stopped in the company in 2006. The SiC based sensors are now commercialized by SenSiC. SiC-FET ammonia sensors were successfully tested on two Volvo trucks during a 10 days excursion in Spain. The two trucks were equipped with urea injection systems in order to reduce the nitrogen oxide emissions. Already in stage I it was shown that SiC based gas sensors can be operated at 1000 °C for a short time and show time constants below a few milliseconds when operated at temperatures ≥ 550 °C . These properties facilitated cylinder-specific monitoring tests on the exhaust gases from real engines at Mecel AB in Åmål. AppliedSensor (formerly NST) is not a real spin-off company due to the activities of S-SENCE since it was started before the start of S-SENCE. However, it is a spin-off company of the research on metal-insulator-semiconductor field effect transistors, MISFETs, that was used in the electronic noses that constituted the scientific base for the establishment of S-SENCE at that time. S-SENCE has been important for the development of the company and the company has been important for the development of S-SENCE. AppliedSensor has carried out development on a hydrogen sensor for safety applications in the automotive segment. In 2007 it was announced that AppiledSensor’s hydrogen gas detection module is incorporated in the BMW Hydrogen 7 which was the first hydrogen driven car in the luxury performance segment. The connection between AppliedSensor and BMW was initiated by Dr. Mats Eriksson during a period as a visiting scientist in Munich 2002. The development was then carried out at AppliedSensor, including former employees at LiU/S-SENCE employed by AppliedSensor, in collaboration with BMW. New types of biosensor surfaces have been developed both for Biacore and Biosensor Applications. The detection of small molecules, explosives and narcotics, was successfully demonstrated using imaging surface plasmon resonance and selective immobilized antibodies. Discrimination of different drugs in a mixture (heroin, ecstasy, cocaine, ...) was obtained. An electronic tongue was implemented in the product line in a dairy industry (Skånemejerier). The electronic tongue could follow milk qualities, change of milk sources, and cleaning efficiency for over six months without any need of service. A method for monitoring water quality at a water production plant of Tekniska Verken was introduced. Successful measurements of the water quality have been performed. Also, an automatic sample handling system has been developed and run during four months. 28 S-SENCE, Summary report 1995-2006 7. Final remarks S-SENCE was established in 1995 as one of VINNOVA’s ”Competence centers” and has during more than ten years been an important player in national and international chemical sensor research and development. Altogether 25 companies have been engaged in S-SENCE over the years. This fact has been valuable both for the researchers at Linköping university and for the involved companies. Several long lasting relationships have been created for continued collaboration. Interestingly several activities within S-SENCE have resulted in new companies, new products and research within other research programs. S-SENCE has been evaluated on several occasions. In connection to an international evaluation in 2003 the following conclusions were drawn by the evaluators, the CEO of one of the industrial partners and the dean of the Institute of Technology and Prorektor of Linköping University, illustrating the success of S-SENCE: • S-SENCE was evaluated by an international evaluation committee in 2003. The evaluators (Prof. John S. Baras, Prof. Claus-Dieter Kohl, Prof. Milena KoudelkaHep and Prof. Per Stenius) conclude that: "Research at S-SENCE is on an internationally leading level. S-SENCE has established an impressive expertise in gas sensors and is also becoming recognized for its work in liquid phase sensor applications. S-SENCE has succeeded in creating a productive and well functioning environment for industry-university collaboration in sensor science and technology, resulting in impressive new sensor technologies as well as successful commercialization and product development. Teaching and training are outstanding and internationally acknowledged." • AppliedSensor was an industrial partner in S-SENCE during stages II-IV and their CEO 2003 Magnus Karlsson writes in a letter on September 4, 2003 on "AppliedSensor´s beneficiary participation in S-SENCE" that : “With a few of NUTEK´s success criteria for S-SENCE; - “Offer the industry an attractive and focused research environment for cooperation, problem solution and long-term competence development.” - “It should be characterized by mutual personnel exchange between the university and the industry.” one can clearly state that S-SENCE has met those criteria’s and that AppliedSensor has benefited from its participation in S-SENCE.” • The dean of the Institute of Technology and Prorektor of Linköping University 2003, Mille Millnert, writes on August 26, 2003 in a letter on "The role and impact of S-SENCE as a center of excellence at Linköping university" that "It has been very interesting to follow the establishment and development of the centers of excellence. Earlier collaborations were mainly based upon bilateral agreements between individual research groups and one or a few industrial partners. The development of them has created a strong infrastructure where partners can join and work together with other companies and researchers from different groups and departments in joint projects. The resources allocated to S-SENCE have resulted in the strong infrastructure mentioned and the creation of a platform for research with 29 S-SENCE, Summary report 1995-2006 a good international reputation that in turn has been important for the generation of further grants to the field. The work within S-SENCE has also resulted in industrial contacts and networks with other research groups (national as well as international) that have been very important for Linköping University. The combination of good science and problem solving of industrially relevant issues offered by the center of excellence is unique. This way of working is necessary to be able to bridge between academic research and industrial improvement of products and process optimization". The research program of S-SENCE has in principle contained three different parts, i) gas sensors and their applications, ii) liquid sensors and their applications, and iii) biosensors and their applications. The gas sensor work, which during the latest years concentrated on sensors for high temperatures based on silicon carbide was partly picked up by a new VINNOVA funded centre, called FunMat, through the active participation of one of S-SENCE co-workers, Prof. Anita Lloyd Spetz, and a few of the previous S-SENCE partners in that program. The liquid sensor work i.e. work on so called electronic tongues has resulted in a spin-off company, Senset, which commercializes the electronic tongue technique while S-SENCE continues the research. The biosensor work is well established and is continued by the research group of Prof. Bo Liedberg. Since the direct VINNOVA funding to S-SENCE ended in mid 2006, the conditions for the activities within the centre changed, for both good and bad. The loss of basic funding from VINNOVA means that some of the economical stability is lost. On the other hand the boundary conditions for cooperation are no longer tied to a master contract, which increases the degrees of freedom for interacting with external partners. It makes among other things international collaborations, e.g. within EUprojects, simpler. It is obvious from national and international research programs that the interesting areas for future academic research are within medical diagnostics, environmental monitoring and civil safety and security. These are the areas that seem to point out the direction for the "new" S-SENCE. 30 S-SENCE, Summary report 1995-2006 Appendix A: Members of the board 1995 – 1997 Lennart Gedda, Stora Billerud (Chairman) Ingemar Lundström, Linköping University Jan Nytomt, Mecel Hasse Odenö, Linköping University * Arne Pettersson, Svenska Lantmännen Maris Hartmanis, Pharmacia Biopharmaceuticals Lennart Nilsson, Eka Nobel * Hasse Odenö, the dean of the Institute of Technology at Linköping university, left in 1996 to become rector at the Mälardalen högskola and was replaced by Mille Millnert, the new dean at the Institute of Technology. Deputy members: Edward Jobson, Volvo Ingvar Kopp, SKL Torgny Ljungberg, Iggesund Paperboard 1998 – 2000 Arne Pettersson, Solstahälsan (Chairman) Öystein Aksnes, Iggesund Staffan Billinger, Asko Cylinda Jan Nytomt, Mecel, Mats Råby, Global Hemostasis Institute Mille Millnert, Linköping University Ingemar Lundström, Linköping University Deputy members: Göran Bengtsson, STORA Nippe Hylander, Assi Domän Edward Jobson, Volvo Ulf Jönsson, Biacore 2001 – 2002 Arne Pettersson, Solstahälsan (Chairman) Staffan Billinger, Asko Cylinda Ingemar Lundström, Linköping University Kjell Lindström, Lund University Per Mårtensson, AppliedSensor Johanna Svanberg, Håfreströms AB Johan Tollin, Vattenfall Deputy members: Edward Jobson, Volvo Anders Moritz, Tekniska Verken 31 S-SENCE, Summary report 1995-2006 Mats Rånby, Global Homeostasis Institute Lars Ödberg, AssiDomän 2003 – 2004 Arne Pettersson, Solstahälsan (Chairman) Kjell Lindström, Lund University Ingemar Lundström, Linköping University Mikael Löfdahl, AppliedSensor Anders Moritz, Tekniska Verken Per Mårtensson, Proxedra Per Salomonsson, Volvo Johanna Svanberg, Håfreströms AB Deputy members: Staffan Billinger, Asko Cylinda Sten-Gunnar Johansson, Mjärdevi Science Park Jörgen Sjödahl, Laboratoriemedicin i Östergötland Christian Vieder, Acreo 2005 – June 2006 Arne Pettersson, Solstahälsan (Chairman) Ingemar Lundström, Linköping University Mikael Löfdahl, AppliedSensor AB Anders Moritz, Tekniska Verken Per Mårtensson, Proxedra Per Salomonsson, Volvo Jörgen Sjödahl, Laboratoriemedicin i Östergötland Johanna Svanberg, Håfreströms AB Deputy members: Staffan Billinger, Asko Cylinda Sten-Gunnar Johansson, Mjärdevi Teknikpark Christian Vieder, Acreo 32 S-SENCE, Summary report 1995-2006 Appendix B: Examinations PhD Theses 1. Amir Baranzahi, High temperature solid state gas sensors based on silicon carbide, device development and applications, Linköping Studies in Science and Technology, 1996, PhD Thesis No. 422. (Employed by LiU-ITN) 2. Eva Hedborg Karlsson, Gas sensitivity of modified metal-oxide-semiconductor devices, Linköping Studies in Science and Technology, 1997, PhD Thesis No. 473. (Employed by FOI) 3. Martin Holmberg, Data evaluation for an electronic nose, Linköping Studies in Science and Technology, 1997, PhD Thesis No. 474. (Employed by FOI) 4. Helena Lidén, Sensor systems for bioprocess monitoring, Lund University, Analytical Chemistry, 1998, PhD Thesis No. 1041. 5. Tomas Eklöv, Methods to improve the selectivity of gas sensor systems, Linköping Studies in Science and Technology, 1999, PhD Thesis No. 573. (Employed by AppliedSensor) 6. Peter Tobias, Silicon carbide field-effect devices studied as gas sensors for exhaust gas monitoring, Linköping Studies in Science and Technology, 1999, PhD Thesis No. 585. (Employed at Michigan State University, East Lansing, USA) 7. Thomas Bachinger, Multisensor arrays for bioprocess monitoring, Linköping Studies in Science and Technology, 1999, PhD Thesis No. 610. (Proxedra, Own company developing software for multivariate data analysis) 8. Nils Paulsson, New instrumentation for forensic applications: Automatic fiber detection and breath alcohol measurements, Linköping Studies in Science and Technology, 2000, PhD Thesis No. 632. 9. Eva-Lotta Kalman, Chemical gas sensors for automobile interiors, Linköping Studies in Science and Technology, 2000, PhD Thesis No. 655. (Own company) 10. Kenny Hansson, Real-time analysis of blood coagulation and fibrinolysis, Linköping University Medical Dissertations, 2001, No. 663. (Employed by AstraZeneca) 11. Mikael Löfdahl, Spatially resolved gas sensing, Linköping Studies in Science and Technology, 2001, PhD Thesis No. 696. (Own company, Docketorp Technologies AB) 12. Per Spångeus, New algorithms for general sensors, Linköping Studies in Science and Technology, 2001, PhD Thesis No. 714. 13. Susanne Holmin, Liquid sensing –Development and characterisation of an electronic tongue based on electrochemical methods, Linköping Studies in Science and Technology, 2002, PhD Thesis No. 735. 14. Lars Unéus, Development and characterization of SiC based sensors for harsh environments, Linköping Studies in Science and Technology, 2002, PhD Thesis No. 736. (Employed by Volvo) 15. Anna Elisabeth Åbom, Materials design and characterization of the active regions of gas sensitive field-effect devices, Linköping Studies in Science and Technology, 2002, PhD Thesis No. 743. (Employed by SAPA) 16. Tom Artursson, Development of pre-processing methods for multivariate sensor data, Linköping Studies in Science and Technology, 2002, PhD Thesis No. 748. (Employed by SICK IVP) 33 S-SENCE, Summary report 1995-2006 17. Charlotte Söderström, Measuring microbial activity with an electronic tongue, Linköping Studies in Science and Technology, 2003, PhD Thesis No. 816. 18. Patrik Ivarsson, Electronic tongues - New sensor technology in household appliances Linköping Studies in Science and Technology, 2003, PhD Thesis No. 846. (Employed by Asko Cylinda) 19. Ye Zhou, Microcontact printing of protein microarray applications, Linköping Studies in Science and Technology, 2004, PhD Thesis No. 886. (Employed by Obducat AB) 20. Helena Wingbrant, Studies on MISiC-FET sensors for car exhaust gas monitoring, Linköping studies in science and technology, 2005, Dissertation 931. (Employed by Scania AB) 21. Anette Salomonsson, New Materials for Gas Sensitive Field-Effect Device Studies, Linköping studies in science and technology, 2005, Dissertation 957. (Employed by Sectra Imtec AB) Licentiate Theses 1. Peter Tobias, Schottky diodes and capacitors based on silicon carbide used as gas sensors, Linköping Studies in Science and Technology, 1998, Licentiate Thesis No. 680. (continued for PhD) 2. Gunnar Forsgren, Evaluation of gas sensors for monitoring volatile compounds emitted from packaging board products, Linköping Studies in Science and Technology, 1999, Licentiate Thesis No. 771 (Employed by Iggesund Paper Board, continued for PhD on part time) 3. Lisa Åbom, Processing and characterization of thin film field effect gas sensors, Linköping studies in science and technology, 2000, Licentiate Thesis No. 836. (continued for PhD) 4. Henrik Svenningstorp, High temperature sensors for exhaust diagnosis, Linköping Studies in Science and Technology, 2000, Licentiate Thesis No. 850. (Employed by Volvo) 5. Lars Unéus, Development and characterisation of MISiC sensors applied for monitoring of hot flue gases, Linköping Studies in Science and Technology, 2000, Licentiate Thesis No. 852. (continued for PhD) 6. Ulrike Koller, The electronic tongue in dairy industry, Linköping Studies in Science and Technology, 2000, Licentiate Thesis No. 859. (Employed by Göteborgs kex) 7. Patrik Ivarsson, Artificial senses – New technology in household appliances, Linköping Studies in Science and Technology, 2000, Licentiate Thesis No. 858. (continued for PhD) 8. Tom Artursson, Data and drift reduction for multivariate data, Linköping Studies in Science and Technology, 2000, Licentiate Thesis No. 862. (continued for PhD) 9. Håkan Johnson, Evaluation of an electronic tongue for monitoring the microbial status of a pulp and paper process, Linköping Studies in Science and Technology, 2000, Licentiate Thesis No. 900. (Employed by a company producing biomolecules) 10. Anders Carlsson, Multivariate characterization of paper machine wet-end chemistry using an electronic tongue, Linköping Studies in Science and 34 S-SENCE, Summary report 1995-2006 Technology, 2000, Licentiate Thesis No. 901. (Employed by LiU as Environmental manager) 11. H. Wingbrant: Development of high temperature SiC based field effect sensors for internal combustion engine monitoring, Linköping Studies in Science and Technology 2003, Thesis no. 1051. (continued for PhD) 12. Anette Salomonsson, Catalytic reactions and hydrogen sensing with Pt- and PdMIS devices, Linköping Studies in Science and Technology 2003, Thesis no. 1060. (continued for PhD) 13. Jenny Carlsson, Surface analytical methods and multivariate data analysis applied to lectin panels, Linköping studies in science and technology, 2004, Licentiate thesis No. 1123. (continued for PhD) 14. Mike Andersson, Development and characterization of SiC based field effect gas sensors and sensor systems for emissions monitoring and control of biomass combustion, Linköping studies in science and technology, 2005, Licentiate thesis No. 1155. (continued for PhD) 15. Roger Klingvall, Field effect gas sensors and SLPT measurement systems, Linköping studies in science and technology, 2006, Licentiate thesis No. 1251 (continued for PhD) Master theses 1. Reine Johansson, Evaluation of the Reponse to Flue Gases of High Temperature Sensors based on Silicon Carbide, Linköping, June 1995, LiTH-IFM-EX-647. 2. Lisa Åbom, Study of synthetic exhausts before and after a catalytic converter with a high temperature electronic nose based on metal-insulator-silicon carbide Schottky diodes, Linköping April 1997, LiTH-IFM-Ex-701. 3. Rongfen Zhu, Development of a suitable package for MISiC sensors to be used in the electronic nose, January 1998, LiTH-IFM-Ex-730. 4. Lars Unéus, Silicon carbide sensors with thin metal gates for detection of ammonia in oxygen rich environments or diesel engine exhausts, February 1998, LiU-IFM-Fysik-Ex-619. 5. Henrik Svenningstorp, Exhaust gas diagnosis by catalytic metal oxide silicon carbide sensors, February 1998, LiU-IFM-Physics-EX-618. 6. Chatarina Wijk, Nitric oxide sensitivity of catalytic metal-insulator-silicon carbide devices, January 1999, LiU-IFM-Fysik-Ex 688. 7. Anders Carlsson, MIS gas sensors with metal thickness gradients. II: Morphology and surface chemistry, LiTH-IFM-Ex-788, Feb. 1999. 8. Chooosri Utaiwasin, MIS gas sensors with metal thickness gradients. I: Laterally resolved gas response, LiTH-IFM-Ex-789, Feb. 1999. 9. Martin Einehag, Hexanal characterisation of metal insulator silicon carbide devices: application to quality of milk, June 1999, LiU-IFM-Ex-815. 10. Maria Stenberg, 20 p, 1999 11. Steve Andersson, 10 p, 1999 12. Björn Widén, Hydrocarbon sensitivity of metal insulator silicon carbide devices in exhaust gases, June 1999, LiTH-IFM-Ex-816. 13. Roger Pettersson, Catalytic reduction of CO and HC in flue gases: Theory and survey of two catalytic converters, 1999, LiTH-IFM-Ex-828. 35 S-SENCE, Summary report 1995-2006 14. Björn Svedberg, SLPT studies of MIS gas sensors with Pd and Pd alloys as metal layers, LiTH-IFM-Fysik-Ex-772, Dec. 1999. 15. Linda Andersson, Tailored nanostructure of the metal gate of gas sensitive MIS devices by means of polystyrene spheres, LiTH-IFM-Fysik-Ex-781, Feb. 2000. 16. Olle Larsson, Prediction of Air/ fuel ratio of individual cylinders in internal combustion SI engines by means of Ion-sense and MISiC sensor signals in a linear regression model, Linköping September 2000, LiU-IFM-Fysik-Ex 833. 17. Gunnar Höst, Hydrocarbon measurement in car exhaust gases using an array of MISiC sensors, Linköping, December 2000, LiTH-IFM-EX-978. 18. Daniel Nilsson, 20 p, 2000 19. Annelie Niva, 10 p, 2000 20. Göran Drott, 20 p, 2000 21. Annelie Drevemo and Andrea Barany, 10p 2000 22. Marcus Andersson, Master of Science in Physics, 2000. 23. Roger Klingvall, Development and analysis of a Rh-MIS gas sensor using SLPT, SEM and AES, LiTH-IFM-Ex-967, March 2001. 24. Tomas Leffler, LaF3 as gate material inMISiC sensors for detection of HF and HCl in flue gases, June 2001, LiTH-IFM-EX-1005. 25. Martin Jönsson, Activation and stability of gas sensitive field effect devices with platinum and iridium gates, LiU-IFM-Fysik Ex 929, Dec. 2001. 26. Christoffer Valgren, “Design and implementation of a nanoprobing MOS gas sensor system, LiTH-IFM -Ex-1058, Dec. 2001. 27. Carina Högberg 10p 2001. 28. Rasmus Jansson 20p 2001. 29. Katarina Nyström, 2001, Protein-array development using piezo-dispenser 30. Mike Andersson, Investigations on silicon carbide based field effect devices for a possible future oxygen sensor for high temperature applications, January 2002, LiTH-IFM-Ex-1113. 31. Marita Persson, Ammonia Response of MISiC and MISiCFET Chemical Sensor Devices with Different Sensing Materials, October 2002, LiU-IFM-Ex-1011. 32. Henrik Petersson, Master of Science in Electrical Engineering, 2002. 33. Anne-Christine Rasmusson 20p 2002 34. Goran Klenkar, 2002, Selective modification of Biacore’s biosensor chips with micro contact printing (mCP) 35. Daniel Tenselius, A MOSFET sensor for hydrogen leakage detection, LiTH-IFM Ex-1121, Feb. 2003. 36. Olof Andersson, 2003, Protein-Micro-array development utilizing Temporary Hydrophobic Barriers and Piezodispensing 37. Karin Wermelin, 2003, modification of Biacore chips using poly(ethylene glycols). 38. Christian Ulrich and Dan Louthander, Interdigitated array (IDA) electrodes for measurements in low conductive media, LiTH-IFM -Ex-1162, 2003. 39. Mårten Lundén, Modification of the catalytic gate material to increase the longterm stabiblity of SiC based field effect sensors, LiTH-IFM -Ex-1316, 2004. 40. Andreas Gällström, Zeolite coated chips for water detection in oil, June 2004, LITH-IFM-EX-04/1313-SE 41. Mikael Beckne, Evaluation of new catalytic metal / oxide combinations for more diverse selectivity patterns of SiC-FET sensors, LITH-IFM-EX-04/1321-SE 42. Kristina Buchholt, Study of a new type of transducer for liquid biosensing applications, LITH-IFM-EX-1404, 2005-03-10 36 S-SENCE, Summary report 1995-2006 43. Elin Becker, Investigations of the Low-Temperature Activity in CO Oxidation over Supported Platinum Catalysts using High-throughput Screening and DRIFT spectroscopy, LITH-IFM-EX-05/1466-SE 44. John Howgate, The design and evaluation of a novel gas sensing measurement system. Part II: Design of simultaneous capacitance and resistance measurement systems for metal insulator semiconductor sensors. Gas response measurements. LITH-IFM-EX-05/1489-SE 45. Vedran Bandalo, The design and evaluation of a novel gas sensing measurement system. Part II: Design of simultaneous capacitance and resistance measurement systems for metal insulator semiconductor sensors. Gas response measurements. LITH-IFM-EX-05/1489-SE 46. Lars Everbrand, MISiCFET-gassensorbaserad reglering av vedeldad villavärmepanna, LITH-IFM-EX-05/1525-SE 47. Carl-Henrik Eriksson, Direktmätning av organiska föroreningar i mark- Behov och möjlig teknik, LiTH-IFM -Ex-1354, 2005. 48. Henrik Malmberg, Inverkan av geologiska parametrar på organiska markföroreningar, ISSN 1400-3821, 2005. 49. Benny Johansson, Co-sputtered thin films as gate materials for field effect sensors, LITH-IFM-EX-06/1587-SE 50. Jens Eriksson, Co-sputterd meta and metal oxide films as gate electrodes in MOS devices for liquid sensor applications, LITH-IFM-EX-06/1589-SE (10p) 51. Pettersson, Brita, Direktmätning av organiska föroreningar i mark : en jämförelse mellan geofysiska metoder och gassensorn Electronic Nose 3320, 2006. 52. Elin Pirard, Design of a gas sensor based probe for in situ measurement of organic pollutants in soil, LiTH-IFM -Ex-1562, 2006. 53. Eric Jonsson, Detektion av kväveoxid och koldioxid med fälteffektsensorer, 2006, ISSN 1650-8297 37 S-SENCE, Summary report 1995-2006 38 S-SENCE, Summary report 1995-2006 Appendix C: Publications Articles in refereed journals 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. M. Karlsteen, A. Baranzahi, A. Lloyd Spetz, M. Willander, and I. Lundström, “Electrical Properties of Inhomogenous SiC MIS structures”, J. Electronic Materials, 24,7 (1995) 853-861. A. Baranzahi, A. Spetz, and I. Lundström, “Gas Sensitive Field Effect Devices for High Temperatures”, Eurosensors VIII, Sept.-94, Toulouse, France, Sensors and Actuators B, 26-27 (1995) 165-169. A. Baranzahi, A. Lloyd Spetz and I. Lundström, “Reversible hydrogen annealing of metal-oxide -silicon carbide devices at high temperatures”, Appl. Phys. Letter, 67, 21 (1995), 3203-3205. J. Subkans, A. Lloyd-Spetz, H. Sundgren, F. Winquist, J. Kleperis, A. Lusis, and I. Lundström, “In situ modification of the NOx and CO sensitivity of thin Pt-gate MOSFET's,” Thin Solid Film268, 1-2, (1995) 140-143. I. Lundström, “Approaches and mechanisms to solid state based sensing”, Sensors and Actuators B, 35-36 (1996) 11-19. I. Lundström and L.-G. Petersson, “Chemical sensors with catalytic metal gates”, J. Vac. Sci. Techn., A 14, 3 (1996) 1539-1545. I. Lundström, “Why bother about gas-sensitive field-effect devices?”, Sensors and Actuators A, special issue in honour of Prof. Simon Middelhoek, 56 (1996) 75-82. T. Börjesson, T. Eklöv, A. Jonsson, H. Sundgren, and J. Schnurer, “Electronic nose for odor classification of grains”, Cereal Chem. 73(4), (1996) 457-461. M. Holmberg, F. Winquist, I. Lundström, F. Davide, C. DiNatale, and A. D’Amico,”Drift counteraction for an electronic nose”, Sensors and Actuators, B35-36 (1996) 528-535. A. Lloyd Spetz, D. Schmeißer, A. Baranzahi, W. Göpel, B. Wälivaara, and I. Lundström, “X-ray photoemission and auger electron spectroscopy analysis of fast responding activated metal oxide silicon carbide gas sensors”, Thin solid Films, 299 (1997) 183-189. P. Tobias, A. Baranzahi, A. Lloyd Spetz, O. Kordina, E. Janzén, and I. Lundström, “Fast chemical sensing with metal-insulator-silicon carbide structures”, IEEE Electron Device Letters, 18, 6 (1997) 287-289. A. Lloyd Spetz, A. Baranzahi, P. Tobias, and I. Lundström, “High temperature sensors based on metal insulator silicon carbide devices”, Phys. Stat. Sol (A), 162 (1997) 493511. A. Baranzahi, A. Lloyd Spetz, M. Glavmo, C. Carlsson, J. Nytomt, P. Salomonsson, E. Jobsson, B. Häggendal, and I. Lundström, ”Response of metal-oxide-silicon carbide sensors to simulated and real exhaust gases”, Sensors and Actuators B, 43, 1-3, (1997) 52-59. T. Eklöv, H. Sundgren and I. Lundström, ”Distributed chemical sensing”, Sensors and Actuators B 45, (1997), 71-77. S. Nakagomi, P. Tobias, A. Baranzahi, I. Lundström, P. Mårtensson, and A. Lloyd Spetz, “Influence of carbon monoxide, water, and oxygen on high temperature catlaytic metal - oxide - silicon carbide structures”, Sensors and Actuators B, 45 (1997) 183-191. A. Baranzahi, P. Tobias, A. Lloyd Spetz, I Lundström, P. Mårtensson, M. Glavmo, A. Göras, J. Nytomt, P. Salomonsson, and H. Larsson, “Fast responding air/fuel sensor for individual cylinder control”, SAE Technical Paper Series 972940, Combustion and Emisson Formation in SI Engines, (1997) 231-240 (SP-1300). C.F Mandenius, T. Eklöv, and I. Lundström, “Sensor fusion with on-line gas emission multisensor arrays and standard process measuring devices in baker´s yeast manufacturing process”. Biotechnol. Bioeng. 55, (1997) 427-438. 39 S-SENCE, Summary report 1995-2006 18. M. Holmberg, F. Davide, C. DiNatale, A. D’Amico, F. Winquist and I. Lundström, “Drift counteraction in odour recognition applications: Lifelong calibration method” Sensors and Actuators, B42, (1997) 185-194. 19. Jonsson, F. Winquist, H. Sundgren, J. Schnürer, and I. Lundström, "Electronic noses for microbial classification of grains", International Journal of Food Microbiology, 35, (1997) 187-193. 20. F. Winquist, H. Elwing and A. Askendal, "Two-dimensional reflectometry visualisation of antigen-antibody binding on solid surfaces", Colloids and Surfaces: Biointerfaces 9, (1997) 59-65. 21. P. Wide, F. Winquist, and D. Driankov ”An air quality sensor system with fuzzy classification”, Measurement Science and Technology 8, (1997) 138-146. 22. E-L. Kalman, F. Winquist, and I. Lundström, ”A new pollen detection method based on an electronic nose”, Atmospheric Environment 31,11, (1997) 1715-1719. 23. T. Eklöv, P. Mårtensson and I. Lundström, ”Enhanced selectivity of MOSFET gas sensors by systematical analysis of transient parameters”, Anal. Chim. Acta. 353, (1997), 291-300. 24. G. Forsgren and S. Sjöström, “Identification of carton board qualities using gas chromatography or gas sensitive sensors in combination with multivariate data analysis”, Nordic Paper and Pulp Research Journal, 12, 4, (1997) 276-281. 25. F. Winquist, P. Wide, and I Lundström, “An electronic tongue based on voltammetry” Analytica Chimica Acta, 357, (1997) 21-31. 26. P. Tobias, P. Mårtensson, A. Baranzahi, P. Salomonsson, I. Lundström, L. Åbom, and A. Lloyd Spetz, “Response of metal –insulator-silicon carbide sensors to different components in exhaust gases”, Sensors and Actuators B, 47 (1998) 125-130. 27. P. Tobias, S. Nakagomi, A. Baranzahi, R. Zhu, I. Lundström, P. Mårtensson, and A. Lloyd Spetz, “Electrical characterization of chemical sensors based on catalytic metal gate-silicon carbide Schottky diodes”, Material Sci. Forum, 264-268 (1998) 1097-1100. 28. P. Tobias, A. Baranzahi, I. Lundström, A. Schöner, K. Rottner, S. Karlsson, P. Mårtensson, and A. Lloyd Spetz, “Studies of the ambient dependent inversion capacitance of catalytic metal - oxide - silicon carbide devices based on 6H and 4H SiC material”, ICSCIII´97, Stockholm, August 31 - September 5, Material Sci. Forum, 264268 (1998) 1089-1092. 29. A. Baranzahi, P. Tobias, A. Lloyd Spetz, P. Mårtensson, L. G. Ekedahl, and I. Lundström, “Chemical sensors with catalytic metal gates: switching behavior and kinetic phase transitions”, J.Elechtrochem. Soc., 145, 10 (1998) 3401-3406. 30. A. Lloyd Spetz, P. Tobias, L-G. Ekedahl, P. Mårtensson, and I. Lundström, ”Fast chemical sensors for emission control”, The Electrochemical Society Interface, 7, 4 (1998) 34-38. 31. C.F. Mandenius, A. Hagman, F. Dunås, S. Sundgren, and I. Lundström, “A multisensor array for visualizing continuous state transitions in biopharmaceutical processes using principal component analysis”, Biosensors and Bioelectronics 13, (1998) 193-199. 32. T. Bachinger, P.,Mårtensson, and C.F. Mandenius, “Estimation of biomass and specific growth rate in a recombinant E. coli batch cultivation using a chemical multisensor array”, J. Biotechnology 60, (1998) 55-66. 33. H. Lidén, C.F. Mandenius, L. Gorton, N. Meinander, I. Lundström, and F. Winquist, “On-line monitoring of a fermentation using an electronic nose”, Anal. Chim. Acta 361, (1998) 223-232. 34. T. Bachinger, H. Lidén, P. Mårtensson, and C.F. Mandenius, “On-line estimation of state variables in baker´s yeast fermentation using an electronic nose”, Food Analysis Seminars. 3, (1998) 85 -91. 35. I. Ljungberg Willing, and A. Brundin, I. Lundström, “Odour Analysis of Paperboard, the Correlation between Human Senses and Electronic Sensors using Multivariate Analysis”, Packag. Technol. Sci., 11, (1998) 59 – 67. 40 S-SENCE, Summary report 1995-2006 36. T. Börjesson, and L. Johnsson, “Detection of common bunt (Tilletia caries) infestation in wheat with an electronic nose and a human panel”, Z. Pflanzenkrankheit und Pflanzenschutz 105 (3), (1998) 306-313. 37. P. Wide, F. Winquist, P. Bergsten and P.Petriu, “The human-based multisensor fusion method for artificial nose and tongue sensor data”, IEEE Transactions on Instrumentation and Measurements, 47, 5, (1998). 38. E-L. Kalman, F. Winquist, I. Lundström, M. Grönberg and A. Löfvendahl, “A semiconductor gas sensor array for the detection of gas emissions from the interior trim materials in automobiles”, SAE Technical Paper 980995 (1998) 1-6. 39. T. Eklöv, G. Johansson, F. Winquist and I. Lundström, “Monitoring sausage fermentation using an electronic nose”, Journal Sci. Food Agric. 76, (1998) 525-532. 40. M. Holmberg, F. Gustafsson, E-G. Hörnsten, F. Winquist, L-E. Nilsson, L. Ljung and I. Lundström, “Bacteria classification based on feature extraction from sensor data”, Biotechnology Techniques 12, 4, (1998) 319-324. 41. F. Winquist, C. Krantz-Rülcker, P. Wide and I. Lundström ”Monitoring of freshness of milk by an electronic tongue on the basis of voltammetry”, Measurement Science and Technology 9, (1998) 1937-1946. 42. H. Liden, C.F. Mandenius, L. Gorton, N. Meinander, I. Lundström and F.Winquist, “On-line monitoring of a cultivation using an electronic nose”, Analytica Chimica Acta 361, (1998) 223-231. 43. F. Winquist, H. Sundgren and I. Lundström, “Electronic Noses for Food Control, in Biosensors for Food Analysis”, 1998, A.O. Scott ed., The Royal Society of Chemistry, Athenaeum Press Ltd, UK. 44. A. Lloyd Spetz, P. Tobias, A. Baranzahi, P. Mårtensson, and I. Lundström, “Current status of silicon carbide based high temperature gas sensors”, IEEE Transactions on Electron Devices, 46, 3 (1999) 561 -566. 45. H. Svenningstorp, P. Tobias, P. Salomonsson, I. Lundström, P. Mårtensson, and A. Lloyd Spetz, “Influence of catalytic reactivity on the response of metal-oxide-silicon carbide sensors to exhaust gases”, Sensors and Actuators B, 57 (1999) 159-165. 46. P. Tobias, A. Lloyd Spetz, P. Mårtensson, A. Baranzahi, A. Göras, and I. Lundström, “Moving gas outlets for the evaluation of fast gas sensors”, Sensors and Actuators B, 58, 1-3 (1999) 389-393. 47. Schmeisser, O. Böhme, A. Yfantis, T. Heller, D. R. Batchelor, I. Lundström, and A. Lloyd Spetz, “Dipole moment of nanoparticles at interfaces”, Phys. Rev. Lett., 83, 2 (1999) 380-383. 48. L. Unéus, P. Tobias, P. Salomonsson, I. Lundström, and A. Lloyd Spetz, “Schottky Diodes with Thin Catalytic Gate Metals for Potential Use as Ammonia Sensors for Exhaust Gases”, Sensors and Materials, 11, 5, (1999) 305-318. 49. C.F. Mandenius, H. Lidén, T. Eklöv, M. T. Taherzadeh, and G. Lidén, “Predicting fermentability of wood hydrolyzates with responses from electronic noses”, Biotechnol. Prog. 15, (1999) 617-621. 50. C.F. Mandenius, Review: “Electronic noses for bioreactor monitoring.”, Adv. Biochem. Eng. Biotechnol. vol 66 (Ed. T. Scheper), (1999) 65-82. 51. E. Hedborg, F. Winquist H. Sundgren and I. Lundström, “Charge migration on silicon dioxide related to its wettability”, Thin Solid Film 340, 1-2, (1999) 250-256. 52. F. Winquist, P. Wide T. Eklöv C. Hjort and I. Lundström “ Crispbread quality estimation based on fusion of information from the sensor analogies to the human olfactory, auditory and tactile senses”, Journal of Food Process Engineering (1999) 337358. 53. F. Winquist, P. Wide and I.Lundström, “The combination of an electronic tongue and an electronic nose”, Sensors and Actuators B58, (1999) 512-517. 54. N. Paulsson and F. Winquist, “Analysis of breath alcohol with a multi sensor array – instrumental setup, characterization and evaluation”, Forensic Science International, 105 (2) (1999) 95-114. 41 S-SENCE, Summary report 1995-2006 55. K.M. Hansson, T. Platou Vikinge, P. M. Rånby, P. Tengvall, I. Lundström, K. Johansen, and T.L. Lindahl, ”Surface Plasmon Resonance (SPR) Analysis of Coagulation in Whole Blood with Application in the Prothrombin Time Assay”, Biosensors and Bioelectronics, 14 (8-9), 671 - 682 (1999). 56. T. Eklöv and I. Lundström, “Distributed sensor systems for quantification of individual components in a multiple gas mixture”, Anal. Chem. 71 (1999) 3544-3550. 57. M. Löfdahl, M. Eriksson, I. Lundström, ”Chemical images”, Sensors and Actuators B 70 (2000) 77-82. 58. M. Pardo, G. Niederjaufner, G Benussi, E. Comini, G. Faglia, G. Sberveglieri, M. Holmberg, and I. Lundstrom, “Signal Processing Enhances the Classification of Different Brands of Espresso Coffee with an Electronic Nose”, Sensors and Actuators B 2000; 69: 397–403 59. P. Tobias, P. Rask, A. Göras, I. Lundström, P. Salomonsson, and A. Lloyd Spetz, “Platinum – Insulator – Silicon Carbide Structures as Small and Fast Sensors for Exhaust Gases”, Sensoren und Messysteme 2000, VDI Berichte 1530, ISBN 3-18091530-7, VDI Verlag, Düsseldorf, March 13-14, (2000) 179-190. 60. S. Savage, and A. Lloyd Spetz, “Silicon Carbide High Temperature Gas Sensors”, Compound Semiconductor, 6, 3 (2000) 76-79. 61. N. Paulsson, E. Larsson and F. Winquist, “Extraction and selection of parameters for evaluation of breath alcohol measurement with an electronic nose”, Sensors and Actuators A, 84 (3) (2000) 187-197. 62. H.Svenningstorp, P. Tobias, P. Salomonsson, I. Lundström, P. Mårtensson, and A. Lloyd Spetz, High temperature gas sensors based on catalytic metal field effect transistors, Mat. Sci. Forum, 338-342 (2000) 1435-1438. 63. T. Bachinger, U. Riese, R. Eriksson, and C.F. Mandenius, “Monitoring process states in a production scale CHO cell cultivation using a chemical multisensor array”, J. Biotechnol. 76, (2000) 61-71. 64. T. Bachinger, U. Riese, R. Eriksson, and C.F. Mandenius, “Electronic nose for estimation of product concentration in mammalian cell cultivation”,. Bioprocess and Biosystems Engineering, 23 (6) (2000) 637-642. 65. T. Bachinger and C.F. Mandenius, “Searching for process information in the aroma of cell cultures”, Trends in Biotechnology,18 (12)(2000) 494-500. 66. L. Åbom, "Processing and characterization of thin film field effect gas sensors", Linköping studies in science and technology, Licentiate thesis no. 836, 2000 67. F. Winquist, S. Holmin, C. Krantz-Rülcker, P.Wide and I.Lundström, “A hybride electronic tongue”, Analytica Chimica Acta, 406 (2000) 147-157. 68. F. Winquist. “The Linköping electronic nose – A short review”, Lipid Forum, 59 (2000) 23-30. 69. T. Platou Vikinge, K.M. Hansson, J. Benesch, K. Johansen, M. Rånby, T.L. Lindahl, B. Liedberg, I. Lundstöm, and P. Tengvall “Blood Plasma Coagulation Studied by Surface Plasmon Resonance” Journal of Biomedical Optics (2000) 5, 51-55 70. T. Platou Vikinge, K. M. Hansson, P. Sandström, B. Liedberg, T. L. Lindahl, I. Lundström, P. Tengvall and F. Höök, “Comparison of surface plasmon resonance and quartz crystal microbalance in the study of whole blood and plasma coagulation”, Biosensors and Bioelectronics, 15 (11-12) (2000) 605-613. 71. J. Olsson, T. Börjesson, T. Lundstedt and J. Schnürer “Volatiles for mycological quality grading of barley grains: determinations using gas chromatography–mass spectrometry and electronic nose”, International Journal of Food Microbiology 59 (3) (2000) 167-178. 72. L. Unéus, P. M.Mattsson, P. Ljung, R. Wigren, P. Mårtensson, L. G. Ekedahl, I. Lundström, and A. Lloyd Spetz, Monitoring of Hot Flue Gases by an E- Nose Equipped with SiC Based Sensors and Metal Oxide Sensors, Electronic Noses and Olfaction 2000,eds. J.W. Gardner, and K.C. Persaud, Institute of Physics Publishing, 2000, pp. 291-296. 42 S-SENCE, Summary report 1995-2006 73. T. Artursson, T. Eklöv, I. Lundström, P. Mårtensson, M. Sjöström, and M. Holmberg, “Drift Correction for Gas Sensors using Multivariate Methods”, Journal of Chemometrics 14 (5-6) (2000) 711-724. 74. H. Lidén, T. Bachinger, L. Gorton, and C. F. Mandenius, “On-line estimation of state variables in Saccharomyces cerevisiae batch cultivations using a chemical multisensor array”, The Analyst, (2000) 125, 1123-1128. 75. A. Lloyd Spetz, L. Unéus, H. Svenningstorp, P. Tobias, L.-G. Ekedahl, O. Larsson, A. Göras, S. Savage, C. Harris, P. Mårtensson, R. Wigren, P. Salomonsson, B. Häggendahl, P. Ljung, M. Mattsson, and I. Lundström: “SiC based Field Effect Gas Sensors for Industrial Applications”, physica status solidi (a), 185, 1, (2001) 15. 76. A.Lloyd Spetz, P. Tobias, L. Unéus, H. Svenningstorp, L.-G. Ekedahl, I. Lundström, High temperature catalytic metal field effect transistors for industrial applications, Sensors and Actutators B, 70 (2000) 67-76. 77. O. Böhme, A. Lloyd Spetz, I. Lundström, D. Schmeisser: “Nanoparticles as the active element of high temperature Metal – Insulator – Silicon Carbide gas sensors”, Adv. Mater., 13, 8, (2001) 597. 78. H. Svenningstorp, B. Widén, P. Salomonsson, L.-G. Ekedahl, I. Lundström, P. Tobias, and A. Lloyd Spetz: “Detection of HC in exhaust gases by an array of MISiC sensors”, Sensors and Actuators B, 77, 177 (2001). 79. M. Löfdahl, C. Utaiwasin, A. Carlsson, I. Lundström and M. Eriksson, “Gas response dependence on gate metal morphology of field-effect devices”, Sensors and Actuators B, 80, 183-192 (2001). 80. Scharnagl, M. Eriksson, A. Karthigeyan, M.Burgmair, M. Zimmer and I. Eisele, “Hydrogen detection at high concentrations with stabilised palladium”, Sensors and Actuators B, 78, (1-3), 138 (2001). 81. T. Bachinger, C-F Mandenius, G. Striedner, F. Clementschitsch, E. Dürrschmid, M. Cserjan-Puschmann, O. Doblhoff-Dier, K. Bayer, "Non-invasive detection of the metabolic burden on recombinant microorganisms during fermentation processes", J. Chem. Technol. Biotechnol., 76 (8) (2001), 885-889 82. D. Briand, B. van der Schoot, N. F. de Rooij, H. Sundgren, I. Lundström, ”Thermally isolated MOSFET for gas sensing application”, IEEE Electron. Device Letter, 22(1), 11, (2001). 83. C. Krantz-Rülcker, M. Stenberg, F. Winquist, I. Lundström, ”Electronic tongues for environmental monitoring based on sensor arrays and pattern recognition: a review”, Analytica Chimica Acta, 426 (2001) 215-224. 84. T. Bachinger, CF. Mandenius, “Physiologically motivated monitoring of fermentation processes by means of an electronic nose”, Chem. Eng. Technol., 24 (7), 33 (2001). 85. P. Ivarsson, S. Holmin, N.-E. Höjer, C. Krantz-Rülcker, and F. Winquist, “Discrimination of tea by means of a voltammetric electronic tongue and different applied waveforms”, Sens. Act. B, 76, (2001), 449-454 86. S. Holmin, P. Spångéus, C. Krantz-Rülcker, and F. Winquist, “Compression of Electronic Tongue Data- A Comparative Study”, Sens. Act. B 76 454 (2001). 87. S. Holmin, C. Krantz-Rülcker, I. Lundström, and F. Winquist, “Drift Correction of Electronic Tongue Responses”, Meas. Sci. & Technol. 12 1348 (2001). 88. Carlsson, C. Krantz-Rülcker, F. Winquist, “An electronic tongue as a tool for wet-end control”, Nordic Pulp and Paper Research Journal, 16 (4) 319-326 (2001). 89. P. Ivarsson, Y. Kikkawa, F. Winquist, C. Krantz-Rülcker, N-E. Höjer, K. Hayashi, K. Toko, I. Lundström, ”Comparison of a voltammetric electronic tongue and a lipid membrane tatse sensor”, Analytica Chimica Acta, 49 (1-2) (2001) 59-68. 90. M. Andersson, M. Holmberg, I. Lundström, A. Lloyd-Spetz, P. Mårtensson, R. Paolesse, C. Di Natale, and A. D’Amico, “Development of a ChemFET sensor with molecular films of porphyrins as sensitive layer”, Sensors & Actuators B 77 (2001) 567–571. 91. F. Davide, M. Holmberg, and I. Lundström, Virtual olfactory interfaces: electronic noses and olfactory displays, in “Communications Through Virtual Technologies: Identity, 43 S-SENCE, Summary report 1995-2006 92. 93. 94. 95. 96. 97. 98. 99. 100. 101. 102. 103. 104. 105. 106. 107. 108. Community and Technology in the Communication Age”, ed. G. Riva and F. Davide, IOS PRESS, Amsterdam, 2001. A. E. Åbom, E. Comini, G. Sberveglieri, L. Hultman and M. Eriksson, "Thin oxide films as surface modifiers of MIS field effect gas sensors", Sensors and Actuators B 85 (1-2) (2002) 109-119 A. E. Åbom, L. Hultman and M. Eriksson, "Properties of combined TiN and Pt thin films applied to gas sensing", J. Vac. Sci. Techn. A 20(3) (2002) 667-673 A. E. Åbom, P. Persson, L. Hultman and M. Eriksson, "Influence of gate metal growth parameters on the properties of gas sensitive field-effect devices", Thin Solid Films 409 (2002) 233-242 S. Nakagomi, H. Shinobu, L. Unéus, L.-G. Ekedahl, R. Yakimova, M. Syväjärvi, A. Henry, I. Lundström, E. Janzén, and A. Lloyd Spetz, Influence of epitaxial layer on SiC Schottky diode gas sensors operated in high temperature conditions, ICSCRM2001, Tsukuba, Japan, Oct. 28- Nov. 2, 2001, Material Science Forum, 389-393 (2002) 14231426. L. Unéus, S. Nakagomi, M. Linnarsson, M. Jansson, B. Svensson, R. Yakimova, M. Syväjärvi, A. Henry, E. Janzén, L.-G Ekedahl, I. Lundström, and A. Lloyd Spetz, The effect of hydrogen diffusion in p- and n-type SiC Schottky diodes at high temperatures, ICSCRM2001, Tsukuba, Japan, Oct. 28- Nov. 2, 2001, Material Science Forum, 389393 (2002) 1419-1422. A. Lloyd Spetz, L. Unéus, H. Svenningstorp, P. Tobias, L.-G. Ekedahl,. Harris, P. Mårtensson, R. Wigren, P. Salomonsson, J. Visser, P. Ljung, M. Mattsson, I. Lundström, and S. Savage, MISiCFET chemical gas sensors for high temperature and corrosive environment applications ICSCRM2001, Tsukuba, Japan, Oct. 28- Nov. 2, 2001, Material Science Forum, 389-393 (2002) 1415-1418. O. Larsson, A. Göras, J. Nytomt, C. Carlsson, A. Lloyd Spetz, T. Artursson, M. Holmberg, I.Lundström, L.-G. Ekedahl, and P. Tobias, Estimation of air fuel ratio of individual cylinders in SI engines by means of MISiC sensor signals in a linear regression model, SAE2002, Detroit, USA, March 4-7, 2002, SAE Technical Paper Series, 2002-01-0847. T. Artursson, P. Spångeus, and M. Holmberg, Variable reduction on electronic tongue data, Analytica Chimica Acta, 452, 2 (2002) p.255-264. F. Davide, M. Andersson, M. Holmberg, and I. Lundström, Chaotic Chemical Sensing, IEEE Sensors Journal, vol. 2, 6 (2002) p. 656-662. T. Artursson and M. Holmberg, Wavelet transform of electronic tongue data, Sensors & Actuators B, 87 (2002) p. 379-391. M. Holmberg and T. Artursson, Drift compensation, standards, and calibration methods, in “Handbook for Electronic Noses“, ed. T. Pearce, and J. Gardner, 2002. D. Filippini and I. Lundström, “Hydrogen detection on bare SiO2 between metal gates” Journal of Appl. Phys. 91, 3896 (2002). J. Olsson, T. Börjesson, T. Lundstedt, and J. Schnurer, “Detection and quantification of ochratoxin A and deoxynivalenol in barley grains by GC/MS and electronic nose”, Int. J. Food Microbiol., 72 (3), 203 (2002). S. Holmin, F. Björefors, M. Eriksson, C. Krantz-Rülcker, F. Winquist. Investigation of New Electrode Materials as Sensors in a Voltammetric Electronic Tongue. Electroanalysis 14 (12) (2002) 839-847. Mikael Löfdahl, Mats Eriksson, Martin Johansson and Ingemar Lundström, Difference in Hydrogen Sensitivity Between Pt and Pd Field-effect Devices. J. Appl. Phys. 91(7) (2002) 4275-4280. S.Nakagomi, A. Lloyd Spetz, I. Lundström and P. Tobias, Electrical characterization of carbon monoxide sensitive high temperature sensor diode based on catalytic metal gateinsulator-silicon carbide structure, IEEE Sensors Journal, 2, 5 (2002) 379-386. T. Bachinger, U. Riese, R.K. Eriksson and C.F. Mandenius, “Gas sensor arrays for early detection of infection in mammalian cell culture”, Biosensors and Bioelectronics, 17(5) (2002) 395-403. 44 S-SENCE, Summary report 1995-2006 109. K. M. Hansson, P. Tengvall, I. Lundström, M. Rånby, and T. L. Lindahl, “Comparative studies with surface plasmon resonance and free oscillation rheometry on the inhibition of platelets with cytochalasin E and monoclonal antibodies towards GPIIb/IIIa.”, Biosensors and Bioelectronics, 17 (9) ( 2002) 761-771. 110. K. M. Hansson, P. Tengvall, I. Lundström, M. Rånby, and T. L. Lindahl,“Surface plasmon resonance and free oscillation rheometry in combination: A new approach for studies on haemostasis and biomaterials.” , Biosensors and Bioelectronics, 17(9) (2002) 747-759. 111. F. Winquist, E. Rydberg, S. Holmin, C. Krantz-Rülcker and I. Lundström"Flow injection analysis applied to a voltammetric electronic tongue", Analytica Chimica Acta 471 (2002) 159-172. 112. F. Winquist, C. Krantz-Rülcker and I. Lundström "Electronic tongues and combination of artificial senses", in Handbook of Machine Olfaction, T. Pierce and J. Gardner ed. 2002 113. F. Winquist, C. Krantz-Rülcker and I. Lundström "Electronic tongues and combination of artificial senses", Sensors Update, 2002 114. S. Holmin, F. Björefors, M. Eriksson C. Krantz-Rülcker and F. Winquist ”Investigations of new electrode materials as sensors in a voltammetric electronic tongue” Electroanalysis 14 (2002) 839 – 847. 115. C. Söderström, H. Boren, F. Winquist and C. Krantz-Rülcker ”Use of an electronic tongue to analyze mold growth in liquid media” International Journal of Food Microbiology, 2002 116. C. Söderström, H. Boren and C. Krantz-Rülcker ”Use of an electronic tongue and HPLC with electrochemical detection to investigate production of redox-active substances as a means of differentiating molds growing in different culture media. ” International Journal of Food Microbiology, 2002 117. C. Söderström, F. Winquist and C. Krantz-Rülcker ”Diffrentiation of six microbial species with an electronic tongue” Sensors and Actuators B, 89 (2002) 248 – 255. 118. E. Åbom, E. Comini, G. Sberveglieri, N. Finnegan, I. Petrov, L. Hultman and M. Eriksson, "Experimental evidence for a dissociation mechanism in NH3 detection with MIS field-effect devices", Sensors and Actuators B: Chemical, 89 (1-2) (2003) 1-8 119. A. E. Åbom, R. T. Haasch, N. Hellgren, N. Finnegan, L. Hultman and M. Eriksson, "Characterization of the metal-insulator interface of field-effect chemical sensors", J. Appl. Phys., 93 (12) (2003) 9760-9768 120. H. Wingbrant, I. Lundström, A. Lloyd Spetz, The speed of response of MISiCFET devices, Sensors and Actuators B, 93 (2003) 286-294. 121. H. Wingbrant, H. Svenningstorp, P. Salomonsson, P. Tengström, I. Lundström, and A. Lloyd Spetz, Using a MISiCFET device as a cols start sensor, Sensors and Actuators B, 93 (2003) 295-303. 122. H. Wingbrant, L. Unéus, M. Andersson, J. Cerdà, S. Savage, H. Svenningstorp, P. Salomonsson,P. Ljung, M. Mattsson, J. H. Visser, D. Kubinski, R. Soltis, S.G. Ejakov, D. Moldin, M. Löfdahl, M. Einehag, M. Persson, and A. Lloyd Spetz, MISiCFET chemical sensors for applications in exhaust gases and flue gases, Material Science Forum, 433-436 (2003) 953-956. 123. J. Cerdà, J.R. Morante and A. Lloyd Spetz, New tunnel Schottky SiC devices using mixed conduction ceramics, Materials Science Forum, 433-436, (2003) 949-952. 124. A.Lloyd Spetz and S. Savage, Advances in FET chemical gas sensors, in Recent Major Advances in SiC, Eds. W.J. Choyke, H. Matsunami and G. Pensl, Springer, Berlin, pp. 879-906, 2003. 125. O. Weidemann, M. Hermann, G. Steinhoff, H. Wingbrant, A. Lloyd Spetz, M. Stutzmann, and M. Eickhoff, The influence of surface oxides on hydrogen-sensitive Pd:GaN Schottky diodes, Appl. Phys. Lett., 83, 4 (2003) 773-775 126. H. Wingbrant and A. Lloyd Spetz, Dependence of Pt Gate Restructuring on the Linearity of SiC Field Effect Transistor Lambda Sensors, Sensor Letters, 1 (December 2003) 2024. Inauguration issue.M. Holmberg, M. Eriksson, C. Krantz-Rülcker, T. Artursson, F. 45 S-SENCE, Summary report 1995-2006 127. 128. 129. 130. 131. 132. 133. 134. 135. 136. 137. 138. 139. 140. 141. 142. 143. 144. 145. Winquist, A. Lloyd-Spetz, and I. Lundström: ”2nd Workshop of the Second Network on Artificial Olfactory Sensing (NOSE II)”, Sensors and Actuators B 101 (2004) 213. M. Wallin, H. Grönbeck, A. Lloyd Spetz and M. Skoglundh: “Vibrational study of ammonia adsorption on Pt/SiO2”, Appl. Surf. Sci., 235 (4) (2004) 487. M. Andersson, P. Ljung, M. Mattsson, M. Löfdahl, A. Lloyd Spetz: “Investigations on the possibilities of a MISiCFET sensor system for OBD and combustion control utilizing different catalytic gate materials”, Topics in Catalysis, 30 / 31, 365 (2004). M. Jansson, M. K. Linnarsson, A. Hallen, B. G. Svensson, N. Achtziger, L. Unéus, A. Lloyd Spetz, and U. Forsberg: “Hydrogen in the Wide Bandgap semiconductor silicon Carbide”, Physica Scripta, T108, 99 (2004). F. Winquist, C. Krantz-Rülcker, and I. Lundström: ”Electronic tongues”, MRS Bulletin 29 (10), 726 (2004). Y. Zhou, O. Andersson, P. Lindberg, and B. Liedberg: “Reversible Hydrophobic Barriers Introduced by Microcontact Printing: Application to Protein Microarrays”, Microchimica Acta, 146, 193 (2004). Y. Zhou, O. Andersson, P. Lindberg, and B. Liedberg: “Protein Microarrays on Carboxy-methylated Dextran Hydrogels: Immobilization, Characterization and Application”, Microchimica Acta, 147, 21 (2004). Y. Zhou, R. Valiokas, and B. Liedberg: “Structural Characterization of Microcontact Printed Arrays of Hexa(ethylene glycol)-Terminated Alkanethiols on Gold”, Langmuir, 20, 6206 (2004). S. Holmin, C. Krantz-Rülcker and F. Winquist “Multivariate optimisation of electrochemically pre-treated electrodes used in a voltammetric electronic tongue” Analytica Chimica Acta, Volume 519, Issue 1, 9 August 2004, Pages 39 M. Eriksson , A. Salomonsson , I. Lundström, D. Briand and A. E. Åbom, "The influence of the insulator surface properties on the hydrogen response of field-effect gas sensors", J. Appl. Phys., 98 (3) (2005) 034903/1 A. Salomonsson , M. Eriksson and H. Dannetun, "Hydrogen Interaction with Platinum and Palladium Metal Insulator Semiconductor devices", J. Appl. Phys., 98 (1) (2005) 014505/1 R. Klingvall , I. Lundström, M. Löfdahl and M. Eriksson, "A combinatorial approach for field-effect gas sensor research and development", IEEE Sensors Journal, 5 (5) (2005) 995 M. Wallin, H. Gronbeck, A. L. Spetz, M. Eriksson and M. Skoglundh, "Vibrational Analysis of H2 and D2 Adsorption on Pt/SiO2", J. Phys. Chem. B. 109 (19) (2005) 9581. Ivarsson P, Krantz-Rülcher C, Winquist F, Lundström I., "A voltammetric electronic tongue", Chemical senses 2005;30, 258. S. Nakagomi, A. Fukumura, Y. Kokubun, S. Savage, H. Wingbrant, M. Andersson, I. Lundström, M. Löfdahl, A. Lloyd Spetz, "Influence of gate bias of MISiC-FET gas sensor device on the sensing properties", Sensors and Actuators B, 108 (2005) 501. Nakagomi S, Wingqvist G, Åbom E, Helmersson U, Lloyd-Spets A. "Hydrogen sensing by NKN thin film with high dielectric constant and ferroelectric property", Sensors and actuators. B, Chemical, 108 (2005) 490. Petersson H, Holmberg M. "Initial studies on the possibility to use chemical sensors to monitor and control boilers", Sensors and actuators. B, Chemical, 2005;111-112, 487. A. Salomonsson, S. Roy, C. Aulin , J. Cerdà , P.-O. Käll , L. Ojamäe , M. Strand, M. Sanati, A. Lloyd Spetz, "Nanoparticles for long term stable, more selective MISiCFET gas sensors", Sensors and Actuators B, 107 (2005) 831. Söderström C, Rudnitskaya A, Legin A, Krantz-Rülcher C., "Differentiation of four Aspergillus species and one Zygosaccharomyces with two electronic tongues based on different measurement techniques. Journal of biotechnology 2005;119, 300. Söderström C, Borén H, Krantz-Rülcher C. "Use of an electronic tongue and HPLC with electrochemical detection to differentiate molds in culture media", International journal of food microbiology 2005;97, 247. 46 S-SENCE, Summary report 1995-2006 146. Unéus L, Artursson T, Mattsson M, Ljung P, Wigren R, Mårtensson P, Holmberg M et al., "Evaluation of on-line flue gas measurements by MISiCFET and metal.oxide sensors in boilers", IEEE sensors journal 5 (1) (2005) 75. 147. H. Wingbrant, H. Svenningstorp, P. Salomonsson, D. Kubinski, J. H. Visser, M. Löfdahl, A. Lloyd Spetz, "Using a MISiC-FET sensor for detecting NH3 in SCR systems", IEEE Sensors Journal, 5, 5 (2005) 1099. 148. S.-K. Lee, Eun-K. Suh, N.-K. Cho, H.-D. Park, L. Unéus and A. Lloyd Spetz, "Comparison study of ohmic contacts to 4H-silicon carbide in oxidizing ambient for harsh environment gas sensor applications", Solid-State Electronics 49 (2005) 1297. 149. H. Wingbrant, M. Lundén, A. Lloyd Spetz, "Modifications of the Gate Material to Increase the Long-Term Stability of Field Effect Transistor Lambda Sensors", Sensor Letters, 3 (2005) 225. 150. Carlsson, J; Mecklenburg, M; Lundstrom, I; Danielsson, B; Winquist, F, "Investigation of sera from various species by using lectin affinity arrays and scanning ellipsometry", Anal. Chim. Acta, 530 (2) (2005) 167. 151. Ivarsson, P; Johansson, M; Hojer, NE; Krantz-Rulcker, C; Winquist, F; Lundstrom, I, "Supervision of rinses in a washing machine by a voltammetric electronic tongue", Sensors and Actuators B: Chemical, 108 (1-2) (2005) 851. 152. Carlsson, J; Winquist, F; Danielsson, B; Lundstrom, I, "Biosensor discrimination of meat juice from various animals using a lectin panel and ellipsometry", Anal. Chim. Acta, 547 (2) (2005) 229. 153. Winquist, F; Bjorklund, R; Krantz-Rulcker, C; Lundstrom, I; Ostergren, K; Skoglund, T, "An electronic tongue in the dairy industry", Sensors and Actuators B: Chemical, 111 (2005) 299. 154. I. Belov, H. Wingbrant, A. Lloyd Spetz, H. Sundgren, B. Thunér, H. Svenningstorp, P. Leisner, "CDF analysis of packaging and mounting solutions for SiC-based gas sensors in automotive applications", Sensor Letters, 4 (2006) 29. 155. H. Wingbrant, M. Persson, A. E. Åbom, M. Eriksson, B. Andersson, S. Simko, D. J. Kubinski, J. H. Visser, A. Lloyd Spetz, "Cosputtered metal and SiO2 layers for use in thick-film MISiC NH3 sensors", IEEE Sensors J., 6, 4 (2006) 887. 156. S. Roy, A. Salomonsson, A. Lloyd Spetz, C. Aulin, P-O. Käll, L. Ojamae, M. Strand, M. Sanati, "Metal oxide nanoparticles as novel materials for field-effect gas sensors", Materials and Manufacturing Processes, 21 (3) (2006) 275. 157. A. Salomonsson, R. M. Petoral Jr., K. Uvdal, C. Aulin, P.-O. Käll, L. Ojamäe, M. Strand, M. Sanati, A. Lloyd Spetz, "Nanocrystalline Ruthenium oxide and Ruthenium in sensing applications -an experimental and theoretical study", J. Nanoparticle Research (2006) 1. 158. A Lloyd Spetz, S. Nakagomi, H. Wingbrant, M. Andersson, A. Salomonsson, S. Roy, G. Wingqvist, I. Katardjiev, M. Eickhoff, K. Uvdal, R. Yakimova, "New Materials for Chemical and Biosensors", Materials and Manufacturing Processes, 21 (2006) 253-256. 159. Lloyd-Spets A, and Wingbrant H., "The influence of catalytic activity on the phase transition governed binary switch point of MISiC-FET lambda sensors", Appl. Surf. Sci. 252 (2006) 7473. 160. Lloyd-Spets A, Fawcett T, Wolan J, Reyes M, Saddow S., "Thermal detection mechanism of SiC based hydrogen resistive gas sensors", Appl. Phys. Lett., 89 (2006) 1. 161. Olsson J, Winquist F, Lundström I., "A self polishing electronic tongue", Sensors and actuators. B, Chemical, 118 (2006) 461. 162. Gutes, A; Cespedes, F; del Valle, M; Louthander, D; Krantz-Rulcker, C; Winquist, F, "A flow injection voltammetric electronic tongue applied to paper mill industrial waters", e: Sensors and actuators. B, Chemical, 115 (1) (2006) 390. 163. Larsson, A., Angbrant, J., Ekeroth, J., Månsson, P., Liedberg, B., " novel biochip technology for detection of explosives-TNT: Synthesis, characterization and application", Sensors &Actuators B. 113, 730 (2006). 47 S-SENCE, Summary report 1995-2006 164. Klenkar, G., Valiokas, R., Lundström, I., Tinazli, A., Tampé, R., Piehler, J. and Liedberg, B., "Piezo dispensed Microarray of multivalent chelating thiols for dissecting complex protein-protein interactions", Anal. Chem. 78, 3643 (2006). 165. Valiokas, R., Klenkar, G., Tinazli, A., Tampé, R., Liedberg, B. and Piehler, J., "Differential protein assembly on micropatterned surfaces with tailored molecular and surface multivalency", ChemBioChem",7, 1325 (2006). Conference contributions 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. I. Lundström, “Chemical sensors with catalytic metal gates”, 42nd National symposium of American Vacuum Society, Oct. 16-20, 1995, Minneapolis, USA. I. Lundström, “Gas sensing with field effect devices”, Seminar on progress on biomemetic sensor technology, Japan society of applied physics, Nov. 16, 1995, Tokyo Japan. I. Lundström, “Field effect devices as gas sensors”, 18th Electrical engineering conference, Nov. 22-24, 1995, Pattaya, Thailand. J. Ohlsson, T. Börjesson and J. Schnürer, “Penicillium identification using an electronic nose”, 2nd International symposium on olfaction and electronic nose, Oct. 2-3, 1995, Toulouse, France. T. Börjesson and J. Ohlsson, “Recognition of common bunt in wheat with an electronic nose”, 2nd International symposium on olfaction and electronic nose, Oct. 2-3, 1995, Toulouse, France. P. Tobias, A. Baranzahi, A. Lloyd Spetz, P. Mårtensson and I. Lundström, ”Some observations on gas sensitive metal oxide silicon carbide devices at high temperatures”, 17th Nordic Semiconducting meeting, June 17 – 20, 1996, Trondheim, Norway. J. Mitrovics, F. Davide, A. Lloyd Spetz, T. Ringvall, G. Hamrefors, D. Sauter, P. Mårtensson, C. DiNatale, U. Weimar, A. D´Amico, I. Lundström, and W. Göpel, “Dynamical analysis of process gases in a PFBC-plant with a hybrid sensor-array”, IMCS´96: The 6:th International Meeting on Chemical Sensors, July 22-25, 1996, Gaithersburg, Maryland, USA. I. Lundström, “Approaches and mechanisms to solid state based sensing”, 6th International meeting on chemical sensors, July 22-25, 1996, Gaithersburg, Maryland, USA. A. Baranzahi, A. Lloyd Spetz, P. Salomonsson, B. Häggendal, P. Mårtensson and I. Lundström, ”Response of metal-oxide-silicon carbide sensors ti simulated exhaust gases”, Proc. of Eurosensors X, Sept. 8-11, 1996, vol 4, Leuven, Belgium. P. Tobias, A. Baranzahi, A. Lloyd Spetz, P. Mårtensson and I. Lundström, ”Platinum metal-insulator-silicon carbide devices operation up to 1000oC”, 1st European conference on silicon carbide and related materials, Oct. 6-9, 1996, Crete, Greece. T. Börjesson, “Detection of off-odours in grain using an electronic nose”, 3rd International symposium on olfaction and electronic nose, Nov. 3-11, 1996, Miami, USA. J. Ohlsson, T. Börjesson and J. Schnürer, “Identification of mould genera using an electron nose”, International union of microbiological societies congresses ’96: International congress of mycological division, Aug. 18-23, 1996, Jerusalem, Israel. C-F. Mandenius, I. Lundström and T. Bachinger, “Experiences of Multisensor arrays for bioreactor monitoring”, 1st European symposium on biochemical engineering, Sept. 1921, 1997, Dublin, Ireland. 48 S-SENCE, Summary report 1995-2006 14. T. Bachinger and C-F. Mandenius, “Bioreactor monitoring using an electronic nose, “1st International symposium on Biochemical Engineering Science, Sept. 1997, Sollentuna, Sweden. 15. B-I. Ljungberg Willing, “Sensory analysis vs. electronic sensors, a comparicy using multivariate analysis”, 3rd International symposium on olfaction and electronic nose, Nov. 3-11, 1996, Miami, USA. 16. C.F. Mandenius, T. Bachinger and I. Lundström, “Multisensor arrays for bioreactor monitoring”, Biochemical Engineering X, Engineering Foundation, May 18-23, 1997, Kananskis, Canada. 17. Lundström “Some physical model studies of biomaterials”, International conference on new biomedical materials, May 25-28, 1997, Portonovo, Italy. 18. Brundin and B-I. Ljungberg Willing, “Die elektronische nase, ein geenetes instrument zur sensorische prufung von dedruckten verpackungen?”, Verpackungs rundschaft, June 1997, Germany. 19. P.Wide, F. Winquist and A. Lauber “The perceiving sensory estimated in an artificial human estimation based sensor system” Proceedings from IEEE Instrumentation and Measurement Technology Conference, 1997. Ottawa, Canada. 20. Lundström, “Distributed chemical sensing”, 1st Gordon Research conference on “chemical sensors and interfacial design”, 28 July –1 August, 1997, New Lond, New Hampshire, UK. 21. T. Bachinger and C.F. Mandenius, “Bioreactor monitoring using an electronic nose”, Symposium Processanaltyisk kemi, Sv Kemistsamfundet, Sept. 25-26 1997, Sollentuna, Sweden 22. T. Bachinger and C.F. Mandenius, “Bioreactor monitoring using an electronic nose”, 4th International Symposium on Olfaction and Electronic Noses, Oct. 6-7, 1997, Nice, France 23. T. Bachinger. P. Mårtensson and C.F. Mandenius, “Multisensor array for on-line monitoring of recombinant fermentation processes using artificial neural networks and principal component analysis”, 8th European Congress on Biotechnology, Aug. 17-21, 1997, Budapest, Hungary. 24. T. Eklöv, P. Mårtensson and I. Lundström, ”Optimizing the information content in parameters extracted from gas sensor response curves”, 1997 Joint International Meeting of the Electrochemical Society and the International Society of Electrochemistry, 31 August – 5 September, 1997, Paris, France. 25. Baranzahi, A Lloyd Spetz, P. Mårtensson, P. Tobias, L-G. Ekedahl and I. Lundström, “Kinetic phase transitions and chemical sensors with catalytic metal gates”, 1997 Joint International Meeting of the Electrochemical Society and the International Society of Electrochemistry, 31 August – 5 September, 1997, Paris, France. 26. P. Tobias, A. Baranzahi, I. Lundström, P. Mårtensson and A. Lloyd Spetz, ”Electrical characterization of chemical sensors based on catalytic metal gate-silicon carbide Schottky diodes”, ICSCII ’97, 31 August – 5 September, Stockholm, Sweden. 27. P. Tobias, A. Baranzahi, I. Lundström, A. Schöner, K. Rottner, S. Karlsson, P. Mårtensson and A. Lloyd Spetz, ”Studies of the ambient dependent inversion capacitance of catalytic metal-oxide-silicon carbide devices based on 6H and 4H SiC material”, ICSCII ’97, 31 August – 5 September, 1997, Stockholm, Sweden. 28. P. Tobias, L. Åbom, A. Baranzahi, P. Salomonsson, I. Lundström and A. Lloyd Spetz, ”Response of metal-insulator-silicon carbide sensors to different components in exhaust gases”, Eurosensors XI, Sept. 21-24, 1997, Warsaw, Poland. 29. Baranzahi, P. Tobias, A Lloyd Spetz, I. Lundström, M. Glavmo, A. Göras, J. Nytomt, P. Salomonsson, H. Larsson and P. Mårtensson, ”Fast responding air/fuel sensor for individual cylinder combustion monitoring”, 1997 SAE Int. Fall Fuels Lubricants Meeting & Exposition, Oct. 13- 16, 1997, Tulsa, Oklahoma, USA. 30. Brundin, “Principal component analysis as a tool to estimate the quality of fibers for food packaging”, 1st Conference on chemometrics, Oct. 17 – 23, 1997, Zhanggjiajie, China. 49 S-SENCE, Summary report 1995-2006 31. Lundström, “Principles of chemical sensor devices”, International conference on recent trends in sensor development for monitoring environmental quality, Dec. 29-31, 1997, Kharagpur, India. 32. T. Bachinger and C.F. Mandenius, “Bioreactor monitoring using an electronic nose”, Analytica Conference 98, April 21-24, 1998, München, Germany. 33. Lloyd Spetz, P. Tobias, P. Mårtensson, and I. Lundström, “Silicon carbide based chemical sensors”, CIMTEC´98, June 15-19, 1998, Florence, Italy. 34. Lloyd Spetz, P. Tobias, R. Zhu, P. Mårtensson, and I. Lundström, “Temperature sensors based on SiC pn-junction diodes”, ECSCRM´98, Sept. 2-4, 1998, Montpellier, France. 35. P. Tobias, L. Unéus, L. Salomonsson, P. Mårtensson, I. Lundström, and A. Lloyd Spetz, “SiC Schottky diodes with catalytic gate metals used as gas sensors for exhaust gases”, ECSCRM´98, Sept. 2-4, 1998, Montpellier, France. 36. T.Bachinger and C.F. Mandenius, “Bioreactor monitoring using an electronic nose”, Second European Symposium on Biochemical Engineering Science, Sept. 16-19, 1998, Porto, Portugal. 37. F. Winquist, “ The electronic nose – Some reflections”, Proceedings to the symposia Electronic Noses in the Food Industry, 1998, Stockholm. 38. P.Wide, F. Winquist, P. Bergsten and P. Petriu, “The human-based multisensor fusion method for artificial nose and tongue sensor data”, IEEE Instrumentation and Measurement Technology Conference, 1998, St Paul, Minnesota, USA. 39. F. Winquist, P. Wide and I. Lundström, “The combination of an electronic tongue and an electronic nose for improved classification of fruitjuices”, Eurosensors XXII, 1998. Southampton, UK. 40. T. Bachinger and C.F. Mandenius, “Bioreactor monitoring using an electronic nose”, International Symposium on Automatic control of food and biological processes”, Sept. 2-23, 1998, Göteborg, Sweden. 41. Krantz-Rülcker, F. Winquist, H. Johnsson, P. Wide and I. Lundström, “Detektion av mikrobiell aktivitet i mjölk och mäld m h a en elektronisk tunga (Detection of microbial activity in milk and white water by using an electronic tongue)”, Livsmedel 98, Oct. 1314, 1998, Göteborg, Sweden. 42. F. Winquist and P. Wide, “Krispighet och munkänsla (Crispiness and mouth feeling)”, Livsmedel 98, Oct. 13-14, 1998, Göteborg, Sweden. 43. S. Holmin, C. Krantz-Rülcker and F. Winquist, ”Klassifiering av filmjölk med elektronisk tunga (Classification of fermented milk by an electronic tongue)”, Livsmedel 98, Oct. 13-14, 1998, Göteborg, Sweden. 44. K.M. Hansson, T. Platou Vikinge, P. Tengvall, I. Lundström, M. Rånby, and T.L. Lindahl, ”Tissue factor induced coagulation of whole blood studied with surface plasmon resonance”, Sept., 1998, Edinburgh, Scotland. 45. P. Tobias, P. Rask, A. Göras, P. Salomonsson, I. Lundström, and A. Lloyd Spetz, “Platinum-insulator-silicon carbide (MISiC) sensors as fast lambda sensors (HEGO)”, Meeting Abstracts, The 195:th meeting of the Electrochemical Society, May 2-6, 1999, Seattle, USA. 46. Lloyd Spetz, P. Tobias, L, Unéus, H. Svenningstorp, L-G. Ekedahl, A. Göras, P. Rask, P. Salomonsson, P. Mårtensson, R. Wigren, P. Ljung, M. Mattsson, and I. Lundström, ”Combustion monitoring field effect gas sensors based on silicon carbide”, Proc. Transducers´99, June 7-10, 1999, Sendai, Japan. 47. T. Bachinger and C.F. Mandenius, “Bioreactor monitoring using an electronic nose”, 1st Symposium of EU network of Excellence of Electronic noses, June 1999, Ispra, Italy. 48. S. Nakagomi, M. Nomoto, P. Tobias, P. Mårtensson, I. Lundström and A. Lloyd Spetz, “Study of CO sensitivity of high temperature field effect sensors based on SiC”, Proc. Transducers´99, June 7-10, 1999, Sendai, Japan. 49. T. Bachinger and C.F. Mandenius, ”Bioreactor monitoring using an electronic nose”, 9th European Congress of Biotechnology, July 15-19, 1999, Brussels, Belgium 50 S-SENCE, Summary report 1995-2006 50. L. Unéus, P.Tobias, P. Mårtenssson, R. Wigren, P. Ljung, M. Mattsson, I. Lundström, L-G. Ekedahl, and A. Lloyd Spetz, “Flue gas monitoring with MISiC and MOS sensors”, Proc. ISOEN´99, Sept. 20-22, 1999, Tübingen, Germany. 51. H. Svenningstorp, P. Tobias, C. Wijk, I. Lundström, P. Salomonsson, L.-G. Ekedahl, and A. Lloyd Spetz, “MISiC Schottky Diodes as NOx sensors in simulated exhausts”, Proc. Eurosensors XIII, Sept. 12-15, 1999, The Hague, The Netherlands. 52. L. Unéus, P. Ljung, M. Mattsson, P. Mårtenssson, R. Wigren, P. Tobias, I. Lundström, L-G. Ekedahl and A. Lloyd Spetz, “Measurements with MISiC and MOS sensors in flue gases”, Proc. Eurosensors XIII, Sept. 12-15, 1999, The Hague, The Netherlands. 53. L. Unéus, H. Svenningstorp, A.M. Saroukhan, S.M. Savage, P. Tobias, I. Lundström, L.G. Ekedahl, A. Konstantinov, C. Harris, and A. Lloyd Spetz, “High temperature TLM measurements of Ni contacts to SiC for high temperature FET gas sensors”, Proc. of ICSCRM´99, Oct. 10-15, 1999, Research Triangle Park, NC, USA. 54. H. Svenningstorp, P. Tobias, P. Salomonsson, I. Lundström, P. Mårtensson, and A. Lloyd Spetz, “High temperature gas sensors based on catalytic metal field effect transistors”, Proc. of ICSCRM´99, Oct. 10-15, 1999, Research Triangle Park, NC, USA. 55. S. Zangooie, H. Arwin, I. Lundström and A. Lloyd Spetz, “Ozone Treatment of SiC for Improved Performance of Gas Sensitive Schottky Diodes”, Proc. of ICSCRM´99, Oct. 10-15, 1999, Research Triangle Park, NC, USA. 56. M.K. Linnarsson, A. Lloyd Spetz, M.S. Janson, L.G. Ekedahl, S. Karlsson, A. Schöner, I. Lundström and B.G. Svensson, “Metal-contact enhanced incorporation of deuterium in 4H- and 6H-SiC”, Proc. of ICSCRM´99, Oct. 10-15, 1999, Research Triangle Park, NC, USA. 57. T. Artursson, “Drift Correction for Gas Sensors using Multivariate Methods”, Oral presentation at the 6th Scandinavian Symposium on Chemometrics, August 15-19 1999, Porsgrunn, Norway. 58. M. Holmberg, “Drift Correction for Chemical Sensors”, Oral presentation at the 1999 SPIE conference on Internal Standardization and Calibration of Chemical Sensors, Sept. 19-22 1999, Boston, USA. 59. T. Artursson, Michael Sjöström, Martin Holmberg, “Drift Counteraction Methods”, Poster presentation at the conference “The 6th International Symposium Olfaction & Electronic Nose”, Sept. 20-22 1999, Tübingen, Germany. 60. M. Eriksson, C. Utaiwasin, A. Carlsson and M. Löfdahl, “On the ammonia response of field-effect devices”, Transducers ’99, June 7-10 1999, Sendai, Japan. 61. M. Eriksson, C. Utaiwasin, A. Carlsson and M. Löfdahl, “On the ammonia response of field-effect devices”, Eurosensors XIII, Sept. 12-15, 1999, The Hague, The Netherlands. 62. M. Löfdahl, A. Carlsson, M. Eriksson, I. Lundström, “Investigation of the Correlation between Gas Response and Catalytic Activity of Palladium Field-Effect Structures”, Eurosensors XIII, 12-15 Sept., 1999, The Hague, The Netherlands. 63. L. Åbom, P. Sandström, L. Hultman, M. Eriksson, “Improved Gas Response Characteristics of Field-Effect Devices by High Temperature Growth of the Gate Metal”, Eurosensors XIII, 12-15 Sept., 1999, The Hague, The Netherlands. 64. E. Hedborg, R. Björklund, M. Eriksson, P. Mårtensson, I. Lundström, “Metal-OxideSemiconductor Field-Effect Gas Sensors Based on Nanostructured SiO2 “, Eurosensors XIII, Sept. 12-15, 1999, The Hague, The Netherlands. 65. Fredrik Winquist. “Electronic noses –Prospects and future”, 20th Nordic Lipid Symposium, June 13-16, 1999, Kolding, Denmark. 66. Krantz-Rülcker, S. Holmin, F. Winquist, L-G. Ekedahl. “A new project area within the activities of S-SENCE – Optimization of processes by multisensing technologies”, ISOEN 99, The 6th International Symposium Olfaction and Electronic nose, Sept.20-22, 1999, Tübingen, Germany. 67. F. Winquist, P. Wide, I. Lundström. “A developing concept –The combination of electronic noses, electronic tongues and additional electronic senses”, The 6th International Symposium Olfaction and Electronic nose, Sept. 20-22, 1999, Tübingen, Germany. 51 S-SENCE, Summary report 1995-2006 68. T. Platou Vikinge, K. Hansson, J. Benesch, K. Johansen, M. Rånby, T. Lindahl, I. Lundström, and P. Tengvall, “Blood plasma coagulation studied by surface plasmon resonance”, BiOS Europe ’98, Medical Sensors and Fibre Optics Sensors IV, Sept. 8-12, 1998, Stockholm, Sweden. 69. T. Platou Vikinge, K.M. Hansson, T.L. Lindahl, M. Rånby, I. Lundström, and P. Tengvall, ”Surface Plasmon Resonance for the Study of Blood and Plasma Coagulation”, ESB annual conference, September, 1999, Boudreaux, France. 70. K.M. Hansson, T. Platou Vikinge, M. Rånby, P. Tengvall, I. Lundström, and T.L. Lindahl, ”Surface Plasmon Resonance, a New Technique to Study Whole Blood Coagulation, Applied on Prothrombin Time Analysis”, XVII CONGRESS OF THE INTERNATIONAL SOCIETY ON THROMBOSIS AND HAEMOSTASIS, Aug. 1421, 1999, Washington, D.C. USA. 71. Lloyd Spetz, “SiC based MOSFET transistors for high temperature industrial gas sensing applications”, The American Physical Society's March 2000 Meeting, March 20-24, 2000, Minneapolis, MN, USA. 72. Lloyd Spetz, M. Eriksson, L.G. Ekedahl, and I. Lundström, “Si and SiC-based field effect devices”, 7:th International Symposium on Trends and Applications of Thin Films (TATF´2000), March 27-30, 2000, Nancy France. 73. Kroutchinine, S. Savage, L. Unéus, H. Svenningstorp, P. Tobias, I. Lundström, “Gas sensing by silicon carbide field effect transistors: device evaluation and applications”, C. Harris, L.G. Ekedahl, Y. Vlasov, and A. Lloyd Spetz, Sensor´2000, June 26-30, 2000, S:t Petersburg, Russia. 74. H. Svenningstorp, B. Widén, P. Salomonsson, P. Tobias, A. Lloyd Spetz et al, “Detection of HC in exhaust gases by an array of MISiC sensors”, 8:th International Meeting on Chemical Sensors, July 2-5, 2000, Basel, Switzerland. 75. P. Tobias, K. Macak, U. Helmersson, I. Lundström, and A. Lloyd Spetz, “Zirconia based oxygen sensor without the need of a reference electrode”, 8:th International Meeting on Chemical Sensors, July 2-5, 2000, Basel, Switzerland. 76. L. Unéus, P. Ljung, R. Wigren, P. Mårtensson, L. G. Ekedahl, I. Lundström, A. Lloyd Spetz, “Flue Gas Measurements with an Electronic Nose Equipped with SiC Based High Temperature Sensors and Metal Oxide Sensors”, ISOEN´2000, July 24-26, 2000, Brighton, England. 77. H. Svenningstorp, P. Tobias, P. Salomonsson, B. Häggendal, I. Lundström, L.G. Ekedahl, and A. Lloyd Spetz, “MISiC Schottky Diodes and Transistors as NH3 Sensors in Diesel Exhausts to Control SCR”, Eurosensors XIV, Aug. 27-30, 2000, Copenhagen, Denmark. 78. Lloyd Spetz, “SiC-based Gas Sensors and their Applications”, ECSCRM2000, Sept. 3-7, 2000, Erlangen, Germany. 79. M.K. Linnarsson, A. Lloyd-Spetz, M.S. Janson, D. Åberg, U. Forsberg, B. Magnusson, A. Henry, and B.G. Svensson, “Hydrogen diffusion in n-type 4H-SiC”, ECSCRM2000, Sept. 3-7, 2000, Erlangen, Germany. 80. M. Andersson, M. Holmberg, I. Lundström, A. Lloyd-Spetz, P. Mårtensson, R. Paolesse, C. Di Natale, A. D'Amico, “MOSFET gas sensors with metalloporphyrins as gas sensitive material”, Oral presentation at “The 5th Italian Conference on Sensors and Microsystems”, Feb. 12-16, 2000, Lecce, Italy. 81. M. Andersson, M. Holmberg, I. Lundström, A. Lloyd-Spetz, P. Mårtensson, R. Paolesse, C. Di Natale, A. D'Amico, “MOSFET gas sensors with metalloporphyrins as gas sensitive material”, poster presentation at “The 8th International Meeting on Chemical Sensors”, July 2-5 2000, Basel, Switzerland. 82. Distante, P. Siciliano, M. Holmberg, and I. Lundström, “Odour Identification under Drift Effect”, oral presentation at “The 7th International Symposium Olfaction & Electronic Nose 2000”, July 20-24, 2000, Brighton, England. 83. Carlsson, C. Krantz-Rülcker, F. Winquist, I. Lundström. ”An electronic tongue as a tool for wet end control”, New measurement techniques for monitoring white water chemistry in papermaking, April 6-7, 2000, Lisbon, Portugal. 52 S-SENCE, Summary report 1995-2006 84. Krantz-Rülcker, M. Stenberg, S. Holmin, C. Söderström, P. Ivarsson, A. Carlsson, F. Winquist, I. Lundström, "Application of multisensor arrays for environmental monitoring and control”. Envirobiosens, Corsica, May 14-17, 2000. 85. Krantz-Rülcker, B. Widén, F. Winquist, I. Lundström. ”Monitoring of drinking water quality by a voltammetric sensor array – an electronic tongue”, 8th International Meeting on Chemical Sensors, July 2-5, 2000, Basel, Switzerland. 86. S. Holmin, P. Spångeus, C. Krantz-Rülcker, I. Lundström, F. Winquist. ”Hierarchical PCA for compression of electronic tongue data”, 8th International Meeting on Chemical Sensors, July 2-5, 2000, Basel, Switzerland. 87. P. Ivarsson, S. Holmin, N-E. Höjer, C. Krantz-Rülcker, I. Lundström, F. Winquist. ”Discrimination of tea by means of a voltammetric electronic tongue and different applied potential modes”, 8th International Meeting on Chemical Sensors, July 2-5, 2000, Basel, Switzerland. 88. F. Winquist, I. Lundström, P. Wide. “An artificial sensor head for human based quality evaluation”, 8th International Meeting on Chemical Sensors, July 2-5, 2000, Basel, Switzerland. 89. P. Ivarsson, författare och titel XXXXXXX “The 7th International Symposium Olfaction & Electronic Nose 2000”, July 20-24 2000, Brighton, England. 90. T. Artursson, P. Spångeus and M. Holmberg, “Variable reduction on electronic tongue data”, poster presentationa at “7th International Conference on chemometric, 2000, Antwerpen, Belgium. 91. T. Artursson, S. Holmin, P. Spångeus and M. Holmberg, “Variable reduction on electronic tongue data”, oral presentation at “The 198th Meeting of the Electrochemical Society”, 2000, Phoenix, USA. 92. S. Savage, H. Svenningstorp, L. Unéus, A. Kroutchinine, P. Tobias, L.-G. Ekedahl, I. Lundström, C. Harris, and A. Lloyd Spetz, SiC based Gas Sensors and their Applications, Proc. of ECSCRM2000, Erlangen, Sept. 3-7, 2000, Mat. Sci. Forum, submitted. 93. S. Holmin, C. Krantz-Rülcker, and F. Winquist. Drift Correction of Electronic Tongue Responses. at the The 199th Meeting of the Electrochemical Society and ISOEN 8. 2001. Washington D.C, USA. Oral 94. Söderström, H. Borén, C. Krantz-Rülcker, F. Winquist, ”Measuring microbial activity with an electronic tongue. at the The 199th Meeting of the Electrochemical Society and ISOEN 8. 2001, Washington D.C, USA. Poster. 95. S. Holmin, C. Krantz-Rülcker, and F. Winquist. Qualitative Analysis of Food Products by Means of a Multi-Sensing Technique- An Electronic Tongue at the 12:e Analysdagarna. 2001, Stockholm, Sweden. Poster. 96. Krantz-Rülcker, “Electronic tongue for environmental monitoring”. Proceedings 1st Senspool Workshop in Alcala de Henares, Spain), May 9-11, 2001. 97. E. Åbom, L. Hultman and M. Eriksson, “Correlation Between Gas Response of MIS Field-Effect Sensors and the Bond Strength Between the Metal and the Insulator Layer of the Device”, AVS 48th International Symposium Oct. 28-Nov. 2, 2001, San Francisco, California, USA 98. M. Löfdahl, M. Eriksson and I. Lundström, ”On the ammonia response mechanism of field-effect gas sensors with thin Pt gates”, AVS 48th International Symposium Oct. 28Nov. 2, 2001, San Francisco, California, USA . 99. D, Briand, T. Knoll, B. van der Schoot, N.F. de Rooij, H. Sundgren, L-G. Ekedahl, I. Lundström and J. Boussey "Advances in processing of MOSFET gas sensors” Conference High temp Oslo, 2001. 100. R. P. Mikalo, P. Hoffman, D. R. Batchelor, A. Lloyd Spetz, I. Lundström, and D. Schmeisser: “Comparison of HF and ozone treated SiC surfaces”, Material Science Forum, 353-356, 219 (2001). 101. S. Jacobsén, U. Helmersson, L. G. Ekedahl, I. Lundström, P. Mårtensson, and A. Lloyd Spetz: “Pt/CeO2 SiC Schottky diodes with high response to hydrogen and 53 S-SENCE, Summary report 1995-2006 102. 103. 104. 105. 106. 107. 108. 109. 110. 111. 112. 113. 114. hydrocarbons”, Transducers´01 and Eurosensors XV, Munich, Germany, June 10-14, 832 (2001) (2D3.05). L. Unéus, M Mattsson, P. Ljung, R. Wigren, P. Mårtensson, L-G. Ekedahl, I. Lundström, and A. Lloyd Spetz: “Evaluation of on-line hot flue gas measurements”, Proc. Transducers´01 and Eurosensors XV, Munich, Germany, June 10-14, 1754 (2001) (4D3.10P). M. Holmberg, Sensors and Data Evaluation – a Powerful Combination, Proceedings of Angelo Workshop, Rome (Italy), July 2, 2001. K. M. Hansson, T. Lindahl, M. Rånby, Koagulation och fibrinolys -nya mätmetoder, 34th Nordic Coagulation meeting, Gothenburg, June 7-9, 2001. Oral presentation. K. M. Hansson, P. Tengvall, I.Lundström, M. Rånby, T. L. Lindahl, Comparative studies with surface plasmon resonance and free oscillation rheometry on the inhibition of platelets with cytochalasin E and monoclonal antibodies towards GPIIB/IIA. XVIII Congress of the International Society on Thrombosis and Haemostasis, Paris, France, July 6-12, 2001. Oral presentation. S. Nakagomi, Y. Sanada, H. Shinobu, L. Unéus, I. Lundström L.-G. Ekedahl, and A. Lloyd Spetz: “Influence of the gate material and temperature on the diode properties of Schottky diodes based on SiC in O2 or CO ambient”, Proc. Transducers´01 and Eurosensors XV, Munich, Germany, June 10-14, 1758 (2001) (4D3.11P). S. Nakagomi, H. Shinobu, L. Unéus, I. Lundström, L.-G. Ekedahl, R. Yakimova, M. Syväjärvi, A. Henry, E. Janzén, and A. Lloyd Spetz: “Influence of epitaxial layer on SiC Schottky diode gas sensors operated in high temperature conditions”, Proc. ICSCRM2001, Tsukuba, Japan, Oct. 28- Nov. 2, 165 (2001). L. Unéus, S. Nakagomi, M. Linnarsson, M. Jansson, B. Svensson, R. Yakimova, M. Syväjärvi, A. Henry, E. Janzén, L.-G Ekedahl, I. Lundström, and A. Lloyd Spetz: “The effect of hydrogen diffusion in p- and n-type SiC Schottky diodes at high temperatures”, Proc. ICSCRM2001, Tsukuba, Japan, Oct. 28- Nov. 2, 289 (2001). Lloyd Spetz, L. Unéus, H. Svenningstorp, H. Wingbrant, C. Harris, P. Salomonsson, P. Tengström, P. Mårtensson, P. Ljung, M. Mattsson, J. H. Visser, S. G. Ejakov, D. Kubinski, L.-G. Ekedahl, I. Lundström, and S. Savage: “MISiCFET chemical gas sensors for high temperature and corrosive environment applications”, Proc. ICSCRM2001, Tsukuba, Japan, Oct. 28- Nov. 2, 231 (2001). L. Unéus, S.-K. Lee, C.-M. Zetterling, L.-G. Ekedahl, I. Lundström, M. Östling, and A. Lloyd Spetz: “Measurements on linear TLM structures with TiW/Ti/Pt contacts for corrosive and high temperature applications”, Proc. ICSCRM2001, Tsukuba, Japan, Oct. 28- Nov. 2, 410 (2001). M. Andersson, A. Avamini, A. Colosimo, A. D’Amico, F. Davide, C. Di Natale, S. Ganci, M. Gutknecht, M. Holmberg, E. Mazzone, M. Nardi, A. Pede, M. Russo, V. Spicacci Minervini, and A. Tibuzzi, ANGELO evaluation: Application of a multisensor system for psycho-physiological stress detection in working environments, 8th International IEEE Conference on Electronics, Circuits, and Systems, ICECS 2001, Malta, Sept. 2-5, 2001. Davide, M. Andersson, M. Holmberg, E. Mazzone, V. Spicacci Minervini, A. D’Amico, A Colosimo, The “Angelo” Project: stress metrology as a pre-condition for improving team-working performance, Sensors and their applications XI, London (UK), Sept. 3-6, 2001. Davide, M. Gutknecht, M. Holmberg, M. Andersson, M. Nardi, A. Pede, A. D’Amico, V. Spicacci Minervini, E. Mazzone, ANGELO: Knowledge Based Virtual Facilitator in Team Working, eBusiness and eWork 2001 (EMMSEC 2001), Venice (Italy), Oct. 1719, 2001. F. Davide, M. Andersson, M. Holmberg, and I. Lundström, Chaotic Chemical Sensing, Proceedings of The 2001 International Symposium on Nonlinear Theory and its Applications (NOLTA2001), Miyagi (Japan), 28 Oct.-1 Nov., p. 489-492, 2001. 54 S-SENCE, Summary report 1995-2006 115. M. Eriksson, D. Briand, I. Grahn and H. Sundgren, Variation of surface chemistry as a means of investigating the response mechanism of field effect gas sensors. 9th International Meeting on Chemical Sensors, July 7-10, 2002, Boston, USA. 116. M. Löfdahl, M. Eriksson and I. Lundström, Lateral resolution limit for field-effect gas sensors, 9th International Meeting on Chemical Sensors, July 7-10, 2002, Boston, USA. 117. Valgren, A.E. Åbom, M. Löfdahl, M. Eriksson and I. Lundström, A system for capacitance measurements with varying metal-oxide gap by nanopositioning. 9th International Meeting on Chemical Sensors, July 7-10, 2002, Boston, USA. 118. A.E. Åbom, C. Valgren, M. Löfdahl, M. Eriksson and I. Lundström, Capacitance probe measurements of gas responses of field effect devices with continuously variable probeoxide gap. 9th International Meeting on Chemical Sensors, July 7-10, 2002, Boston, USA. 119. O.Larsson, A. Göras, J. Nytomt, C. Carlsson, A. Lloyd Spetz, T. Artursson, M. Holmberg, I. Lundström, L.-G. Ekedahl, and P. Tobias, Estimation of air fuel ratio of individual cylinders in SI engines by means of MISiC sensor signals in a linear regression model, SAE2002, Detroit, USA, March 4-7, 2002, (2002-01-0847). 120. J. Cerdá, H. Wingbrant, H. Svenningstorp, J. R. Morante, L. Unéus, and A. Lloyd Spetz, MISiCFET ammonia gas sensors: a comparison between Pt and Ir based metal gates, Proc. 9IMCS, Boston, USA, July 7-10, 2002, pp. 502-503. 121. S.-K. Lee, L. Uneus, S.-M. Koo, C.-M. Zetterling, L.-G. Ekedahl, I. Lundström, A. Lloyd Spetz, and M. Östling, Comparison study of Ohmic contacts in oxidizing ambient at high temperature for gas sensor applications, Proc. TMS Electronic Materials Conference (EMC), 2002, Santa Barbara, USA. 122. M. Andersson, J. Cerdá, L. Unéus, J. R. Morante and A. Lloyd Spetz, The use of differences in catalytic activity between Pt and Ir as gate metals on MISiCFET sensors for exhaust and flue gas monitoring, EUCHEM2002, Gothenburg, Sweden, October 2002 123. I Lundström “Voltammetric electrodes for electronic tongues” 1st NOSE II short courses (Winter School), Bressanone Italy Feb. 2002. 124. C. Comina, S. Holmin, P. Ivarsson, C. Krantz-RülckerPoster ”COD detrmination with an electronic tongue. Workshop Senspool-Sensors for monitoring water pollution from contaminated land, London 2002 125. A. Lloyd Spetz, SiC a chemically inert material for bio- and chemical sensors, The American Ceramic Society, April 27-30, 2003, Nashville, Tenneesse, USA. 126. M. Andersson, H. Wingbrant, L. Unéus, H. Svenningstorp and A. Lloyd Spetz, The use of MISiCFET gas sensors with catalytic gate materials, exhibiting differences in selectivity, for combustion and SCR control in car exhausts and flue gases, Proc. CAPoC6 in Brussels, Belgium, October 22-24, 2003, pp.555-565. 127. S. Nakagomi, M. Takahashi, Y. Kokubun, L. Unéus, Susan Savage, H. Wingbrant, M. Andersson, I. Lundström, M. Löfdahl, A. Lloyd Spetz: “The Influence of Substrate Bias on the Amplification of a Junction Field Effect Transistor Based on Silicon Carbide with a Catalytic Gate Electrode”, Proc. ICSCRM2003, Lyon, France, October 5-10, 2003, pp. 1507-1510. 128. A. Lloyd Spetz, H. Wingbrant, M. Andersson, M. Löfdahl, M. Einehag, P. Ljung, M. Mattsson, H. Svenningstorp, J. H. Visser, D. Kubinski, , P. Salomonsson, and S. Savage, MISiCFET Sensor arrays for On Line Diagnosis, Proc. IEEE Sensors 2003,Toronto, Canada, October 22-24, 2003, pp. 385-386 129. S. Nakagomi, M. Takahashi, L. Unéus, S. Savage, H. Wingbrant, M. Andersson, I. Lundström, M. Löfdahl, A. Lloyd Spetz, MISiC-FET Devices with Bias Controlled Baseline and Gas Response, Proc. IEEE Sensors 2003,Toronto, Canada, October 22-24, 2003, pp. 407-408. 130. J. Cerda, J. R. Morante and A. Lloyd Spetz: “BaSnO3 Oxygen Sensors without the need of a Reference Electrode”, Proc. IEEE Sensors 2003,Toronto, Canada, October 22-24, 2003, pp. 403-404. 55 S-SENCE, Summary report 1995-2006 131. H. Wingbrant, M. Persson, A.E. Åbom, A. Lloyd Spetz, Co-sputtered metal and SiO2 layers for use in thick-film ammonia MISiCFET sensors, IEEE Sensors, Toronto, Canada Oct. 22-24, 2003, submitted. 132. H. Wingbrant, H. Svenningstorp, P. Salomonsson, J. Visser, D. Kubinski, Anita Lloyd Spetz, Using a MISiCFET sensor for detecting NH3 in SCR systems, IEEE Sensors, Toronto, Canada Oct. 22-24, 2003, submitted. 133. T. Artursson, M. Holmberg, D. Lindgren, S. Nyström, and H. Petersson, A Method for Extraction of Predefined Information from Electronic Tongue Measurements, Poster presentation at the NOSE II workshop, Linköping, Sweden, May 18-21, 2003. 134. R. Klingvall, I.Lundström, M. Löfdahl, M. Eriksson, 2D-evaluation of the gas response of a RhPd-MIS devic, 2nd IEEE international conference on sensors, Toronto, Canada, October 22-24, 2003, accepted 135. H. Wingbrant, H. Svenningstorp, P. Salomonsson, D. Kubinski, J. Visser, M. Löfdahl, Anita Lloyd Spetz, Using a MISiC-FET sensor for detecting NH3 in SCR systems, IEEE Sensors Journal, Proc. IEEE Sensors 2003,Toronto, Canada, October 22-24, 2003, accepted. 136. H. Wingbrant, H. Svenningstorp, P. Salomonsson, D. Kubinski, J. Visser, M. Löfdahl, Anita Lloyd Spetz, Using a MISiC-FET sensor for detecting NH3 in SCR systems, IEEE Sensors Journal, Proc. IEEE Sensors 2003,Toronto, Canada, October 22-24, 2003, accepted 137. H. Petersson, M. Andersson, A. Lloyd Spetz, N. Padban, J. Larfeldt, and M. Holmberg: "Initial studies on the possibility to use chemical sensors to monitor and control boilers", Eurosensors XVIII, Rome, Italy, 12-15 Sept. (2004). 138. Andersson, M., Petersson, H., Padban, N., Larfeldt, J., Holmberg, M., Spetz, A.L., "The characteristics and utility of SiC-FE gas sensors for control of combustion in domestic heating systems", (2004) Proceedings of IEEE Sensors, 3, art. no. W1L-A.3, 1157. 139. Brännström, M., Lennartsson, R., Lauberts, A., Habberstad, H., Holmberg, M., "Distributed data fusion in a ground sensor network", (2004) Proceedings of the Seventh International Conference on Information Fusion, FUSION 2004, 2, 1096. 140. J. Cerdà, A. Salomonsson, M. Strand, M. Sanati, A. Lloyd Spetz: “Pt/gamma-Al2O3 particles for long term stable, highly selective MISiCFET gas sensors”, Proc. IMCS10, Tsukuba, Japan, July 12-14 (2004) 3E01. 141. H. Wingbrant, M. Lundén and A. Lloyd Spetz: “Modifications of the catalytic gate material to increase the long-term stability of SiC-FET lambda sensors”, Proc. IMCS10, Tsukuba, Japan, July 12-14 (2004) 2P108. 142. H. Wingbrant and A. Lloyd Spetz: “The influence of catalytic activity and temperature on the binary switch point and linear behavior of SiC-FET lambda sensors”, Proc. IMCS10, Tsukuba, Japan, July 12-14 (2004) 2D10. 143. S. Nakagomi, A. Fukumura, Y. Kokubun, S. Savage, H. Wingbrant, M. Andersson, I. Lundström, M. Löfdahl, A. Lloyd Spetz: “Influence of gate bias of MISiC-FET gas sensor device on the sensing properties”, Proc. IMCS10, Tsukuba, Japan, July 12-14 (2004) 3E02. 144. S. Nakagomi, G. Wingqvist, A. E. Åbom, A. Lloyd Spetz: “Hydrogen sensing by NKN thin film with high dielectric constant and ferro-electric property”, Proc. IMCS10, Tsukuba, Japan, July 12-14 (2004) 2P123. 145. M. Andersson, J. Larfeldt, N. Padban, M. Löfdahl, A. Lloyd Spetz: “Gas sensor based control of small and medium sized boilers”, Proc. IEEE Sensors, Vienna October 24-27 (2004). 146. A Lloyd Spetz, H. Wingbrant, M. Andersson, A. Salomonsson, S. Roy, G. Wingqvist, I. Katardjiev, M. Eickhoff and S. Nakagomi: “New Materials for Chemical and Biosensors”, Proc. International Symposium on Advanced Materials and Processing (ISAMAP2K4) Kharagpur, India, 6-8 Dec. (2004), p. 755. 147. S. Roy, A. Salomonsson, A. Lloyd Spetz, C. Aulin, P. –O. Käll, L. Ojamäe, M. Strand, M. Sanati: ”Metal oxide Nanoparticles as Novel Gate Materials for Field Effect Gas 56 S-SENCE, Summary report 1995-2006 148. 149. 150. 151. 152. 153. 154. 155. 156. 157. 158. 159. 160. 161. 162. 163. 164. Sensors”, Proc. International Symposium on Advanced Materials and Processing (ISAMAP2K4) Kharagpur, India, 6-8 Dec. (2004), p. 983. Belov, H. Wingbrant, A. Lloyd Spetz, H. Sundgren, B. Thuner, H. Svenningstorp, P. Leisner: "Thermal and flow analysis of SiC-based gas sensors for automotive applications", Proc. of the 5th IEEE conference EuroSimE 2004, Brussels, May 9-12, 2004, pp. 475-482. S. Nakagomi, M. Takahashi, Y. Kokubun, L. Unéus , S. Savage, H. Wingbrandt, M. Andersson, I. Lundström, M. Löfdahl, A. Lloyd Spetz: "Substrate Bias Amplification of a SiC Junction Field Effect Transistor with a Catalytic Gate Electrode", Mat. Sci. Forum, 457-460 (2004) 1507-1510. R. Klingvall, I. Lundström, and M. Eriksson: ”Chemical images as a tool for optimising gas sensor properties”, The 10th International Meeting on Chemical Sensors (10IMCS), Tsukuba, Japan, July 12-14 (2004) M. Eriksson, D. Tenselius, M. Einehag and M. Löfdahl: "Controlling the sensitivity region of hydrogen sensitive field effect devices", The 10th International Meeting on Chemical Sensors (10-IMCS), Tsukuba, Japan, July 12-14 (2004) F.Winquist, R.Bjorklund, C.Krantz-Rülcker, I.Lundström, K.Östergren and T.Skoglund: "An electronic tongue in the dairy industry". Eurosensors XIIX, Rome, Italy, 2004 B. Liedberg, Y. Zhou, O. Andersson and P. Lindberg: "Microarray production on polymeric hydrogels using microcontact printing", ESF Workshop Protein arrays – bridging the gap between physics and biomedicine, Jena, Germany, 1-3 April 2004 M. Andersson, H. Pettersson, N. Padban, J. Larfeldt, M. Holmberg, A. Lloyd Spetz, "The characteristics and utility of SiC-FE gas sensors for control of combustion in domestic heating systems", Proc. IEEE Sensors, Vienna, Austria, October 24-27, 2004, p. 1157-1160 (W1L-A3) A. Lloyd Spetz, "SiC a sensor material for extreme environment", MRS Spring Meeting, April 12-16, 2004, San Fransisco, CA, USA, 2004, *J3.1, Invited talk Mats Eriksson, "Gas Sensor Research and Development with a Combinatorial Approach", MRS fall meeting, Boston , USA , Nov. 27 – Dec. 1, 2005 – invited talk A. Salomonsson, S. Roy, C. Aulin, L. Ojamäe, P.-O. Käll, M. Strand, M. Sanati, A. Lloyd Spetz, "RuO2 and Ru nanoparticles for MISiC-FET gas sensors", Proc. Nanotech 2005 (NSTI), Anaheim, USA, May 8-12, Vol. 2, 4, pp. 269-272, 2005. C. Vahlberg, G.R. Yazdi, R. M. Petoral Jr., M. Syväjärvi, K. Uvdal, A. Lloyd Spetz, R. Yakimova, "Surface engineering of functional materials for biosensors", Proc. IEEE Sensors 2005, Irvine, Ca USA, Oct 31-Nov.3, 2005, pp. 504-507. G. Wingqvist, J. Bjurström, L. Liljeholm, I .Katardjiev, A. Lloyd Spetz, "Shear mode AlN thin film electroacoustic resonator for biosensor applications", Proc. IEEE Sensors 2005, Irivine CA, USA, Oct 31 - Nov. 3, 2005, pp. 492-495. M. Andersson, H. Wingbrant, A. Lloyd Spetz, "Study of the CO Response of SiC based Field Effect Gas Sensors", Proc. IEEE Sensors 2005, Irivine, USA, October 31November 2, 2005, pp. 105-108. A Lloyd Spetz, K. Uvdal, M. Eickhoff, I. Katardjiev, and R.Yakimova, "Wide Band-gap Materials for Chemical and Biosensors", Int. Symp. for Advanced Sensor Technologies, Tokyo, Japan, June 10, 2005, pp. 25-30, Invited talk. D. Lutic, M. Strand, A. Salomonsson, L. Ojamäe, P-O. Käll, A. Lloyd Spetz and M. Sanati, "In2O3 particle films as gate material for MISiC-capacitor sensors", NOSA2005, Göteborg, Sweden. M. Strand, A. Salomonsson, J. Einvall, C. Aulin, L. Ojamäe, P-O. Käll, A. Lloyd Spetz, and M. Sanati, "Nanoparticles as sensing material for selective and stable SiC-FET gas sensor", in Proceeding “European Aerosol Conference 2005”, Editor M. Maenhaut, Ghent, Belgium, 28 Aug – 2 Sep, pp. 735. Roger Klingvall, Ingemar Lundström and Mats Eriksson, "Low concentration detection of hydrogen", The 11th International Meeting on Chemical Sensors (IMCS 11), Brescia , Italy , July 16-19, 2006 57 S-SENCE, Summary report 1995-2006 165. R. Yakimova, G. Steinhoff, V. Khranovskyy, C. Vahlberg, R. M. Petoral Jr., G. R. Yazdi, M. Syväjärvi, M. Eickhoff, K. Uvdal, A. Lloyd Spetz, "New material concepts and device architecture of transducers for chemical and bio-sensors", E-MRS meeting, Nice France, May 29- June 1, 2006 (invited talk, Yakimova). 166. K. Buchholt, E. Ieva, P.-O. Käll, L. Ojamäe, L. Torsi, D. Lutic, M. Strand, M. Sanati and A. Lloyd Spetz, "FET devices with gold nanoparticle gate material as nitrogen oxide gas sensors", Proc. E-MRS 2006, Nice France, May 29- June 1, 2006. 167. Doina Lutic, Michael Strand, Anita Lloyd-Spetz, Mehri Sanati, "Catalytic properties of oxide nanoparticles applied in gas sensors", Proc. 12th Nordic Symposium on Catalysis, Trondheim, Norway, May 28-30, 2006. 168. K.Buchholt, E. Ieva, B. Johansson, P. Käll, L. Torsi, A. Lloyd Spetz, "SiC-Field Effect Gas Sensor using Au as Gate Material for NOx sensing", Proc. IMCS11, Brescia, Italy, July 16-19, 2006, MP49 # 130. 169. M. Andersson, A. Lloyd Spetz, "Study of the CO response characteristics of SiC based field effect gas sensors", Proc. IMCS11, Brescia, Italy, July 17-19, 2006, TO1.4.3 170. G. Steinhoff, R. Petoral, C. Vahlberg, B. Baur, T. Wassner, M .Eickhoff, A. LloydSpetz, R. Yakimova, K. Uvdal, "Chemical functionalization of GaN and ZnO surfaces", Proc. IMCS11, Brescia, Italy, July 17-19, 2006, WP78. 171. M. Strand, A. Salomonsson, J. Einvall, C. Aulin, L. Ojamäe, P-O. Käll, A. Lloyd Spetz, and M. Sanati, "Nanoparticles as sensing material for selective and stable SiC-FET gas sensor", Proc. European Aerosol Conference 2005, Ghent, Belgium, 28 Aug – 2 Sep, 2006, p. 735. 172. R.M. Petoral Jr., G.R. Yazdi, C. Vahlberg, M. Syväjärvi, A. Lloyd Spetz , K. Uvdal and R. Yakimova, "Surface functioanlization of SiC for biosensor applications", Proc. ECSCRM 2006, Sept. 3-7, 2006, Newcastle, UK. 173. E. Ieva, N. Cioffi, L. Torsi, L. Sabbatini, P.G. Zambonin, P.O. Kall, A. L. Spetz, “Nanoparticelle di oro come materiali attivi in capacitori impiegati come sensori di gas” Conf Proc. Conf. On Chemical Sensors, Florence, Italy, 10-15 September 2006. 174. A. Lloyd Spetz, G. Steinhoff, V. Khranovsky, M. Andersson, K. Buchholt, M. Eickhoff, R. Yakimova, "Multisensing by Gas Sensors", Proc. Eurosensors XX, Göteborg, Sweden, September 18-20, 2006. T3A-KN, Key note speaker 175. C. Di Natale, K. Buchholt, E. Martinelli, R. Paolesse, A. D´Amico, I. Lundström, A. Lloyd Spetz, "Investigation of the selectivity properties of metalloporphyrines selfassembled-monolayers on QMB and FET transducers", Proc. Eurosensors XX, Göteborg, Sweden, September 18-20, 2006, T1A-P11. 176. R.M. Petoral Jr., G. Steinhoff, G.R. Yazdi, V. Khranovskyy, A. Lloyd Spetz, K. Uvdal, R. Yakimova, "Preparation and characterization of organic/inorganic structures based on ZnO", 4th Int. Workshop on ZnO and related materials, 3-6 Oct. 3-6, 2006, Giessen, Germany 177. A. Lloyd Spetz, G. Steinhoff, R. Petoral Jr, K. Uvdal, M. Eickhoff, and R. Yakimova, "New Materials for Multifunctional Chemical- and Biosensors", MS&T´06, Cincinnati, Ohio, USA, October 15-19, 2006, Invited talk. 58 S-SENCE, Summary report 1995-2006 Appendix D: IPR results Patents: 1. “Method and device for gas sensing”; Amir Baranzahi, Anita Lloyd Spetz, Ingemar Lundström (SE503265, WO96/09534, US6,109,094) 2. ”Testing of catalyst in the exhaust system of an internal combustion engine”, Amir Baranzahi, Anita Lloyd Spetz, Ingemar Lundström, (SE505910, WO9715751). 3. “Sensor for detecting of non-burnt hydrocarbons”, Amir Baranzahi, Anita Lloyd Spetz, Ingemar Lundström, (SE515412, WO9715826). 4. “Method and device for expansion of sensor selectivity”, Ingemar Lundström, Hans Sundgren, (SE505040, WO9705476, EP0840892, US6187597). 5. “Device for gas sensing”, Ingemar Lundström, Per Mårtensson, (SE514042, WO9958964, EP1076816, US6,569,779). 6. “An electronic tongue”, Fredrik Winquist, Peter Wide, (EP1010005) 7. “A method for detecting contaminating microorganisms”, Carl-Fredrik Mandenius, Thomas Bachinger, (SE9904125, WO0136664). 8. “Low power sensor”, Danick Briand, Bart van der Schoot, Nico F. de Roij, Ingemar Lundström, Hans Sundgren, (SE9902081, WO 0075649, EP1190242). 9. “Manufacturing method for integrated sensor arrays”, Per-Erik Fägerman, (EP1022561, US6410445, JP200221161). 10. ”System, sensor combination and method for regulating, detecting as well as deciding current fuel-air ratios in combustion engines”, Amir Baranzahi, Per Mårtensson, Anders Göras, Per Salomonsson, (SE 9703754, US6,526,954, WO9919611, EP1036260) 11. “Method and apparatus for enriching volatile substance (volatile substances) from a gas stream and metering the substance or substances to an analytical instrument"” Iggesund MoDo, Jonas Erik Andersson, Mölndal, Sverige och Britt-Inger Ljungberg-Willing, (SE 512229, WO9966305). 12. “A method for cleaning of washing/dishwashing articles in a washing/dishwashing machine and a device for performing the method” Electronic tongue in dish washers and washing machines”, Patrik Ivarsson, Nils Erik Höjer, Christina Kranz-Rülcker, Fredrik Winquist, (SE 0004400-8, AU 2429802, WO0244460). 13. "Determination of Polymerization/Coagulation in a fluid", Pentti Tengvall and Ingemar Lundström, (US6379976, EP1058848). 59 S-SENCE, Summary report 1995-2006 14. “Method for indication (Optimal Discriminant Projection)”, Per Spångeus, David Lindgren, (SE518681). 15. “Method for indication (Good and Bad Projection)” Per Spångeus, David Lindgren, (SE517171). 16. “Electronic tongue as ozone detector”, Fredrik Winquist, Carina Högberg, Tina Krantz-Rülcker, Kjell Ekberg, (US6,841,053) 17. “Method and system for a voltammetric characterization of a Liquid sample”, Arnold Olofsson, (US6,664,776) 18. “Detection or analysis of urea in liquid involves use of voltammetric electronic tongue” Rasmus Jansson, Per Langö, Fredrik Winquist, Kristina KrantzRülcker, (SE523961). In a bilateral project, fully financed by the company Otre AB. 19. “Simplified signal processing method for voltammetry”, Rasmus Jansson, Patent application (SE524574). 20. "Measurement system for sensors", Fabrizio Davide, Ingemar Lundström, Marcus Andersson, Martin Holmberg, (SE524708) 21. “Field effect sensing device with stabilized working point”, Niclas Edvardsson, Mats Eriksson (EP1927852 A1, pat. Pending) (Submitted Dec. 2006 but based on work performed during spring 2006) 60