Figure 2.4 Receptor-mediated Endocytosis

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Figure 2.4 Receptor-mediated Endocytosis
Figure 2.4
Receptor-mediated
Endocytosis
Process Diagrams Step-by-Step
Copyright © 2007 by John Wiley & Sons, Inc.
1 Binding
Receptor-LDL
complex
LDL particle
Receptor
Clathrin-coated
pit
Plasma
membrane
Invaginated plasma
membrane
1 Binding
Receptor-LDL
complex
Plasma
membrane
LDL particle
Receptor
Clathrin-coated
pit
Invaginated plasma
membrane
2 Vesicle formation
Clathrin-coated
vesicle
1 Binding
Receptor-LDL
complex
Plasma
membrane
LDL particle
Receptor
Clathrin-coated
pit
Invaginated plasma
membrane
2 Vesicle formation
Clathrin-coated
vesicle
3 Uncoating
Uncoated vesicle
1 Binding
Receptor-LDL
complex
Plasma
membrane
LDL particle
Receptor
Invaginated plasma
membrane
Clathrin-coated
pit
2 Vesicle formation
Clathrin-coated
vesicle
3 Uncoating
Uncoated vesicle
4 Fusion with
endosome
Endosome
Transport
vesicle
1 Binding
Receptor-LDL
complex
Plasma
membrane
LDL particle
Receptor
Invaginated plasma
membrane
Clathrin-coated
pit
2 Vesicle formation
Clathrin-coated
vesicle
3 Uncoating
Transport
vesicle
Uncoated vesicle
4 Fusion with
endosome
5 Recycling
of receptors
to plasma
membrane
Endosome
Transport
vesicle
1 Binding
Receptor-LDL
complex
Plasma
membrane
LDL particle
Receptor
Invaginated plasma
membrane
Clathrin-coated
pit
2 Vesicle formation
Clathrin-coated
vesicle
3 Uncoating
Transport
vesicle
Uncoated vesicle
4 Fusion with
endosome
5 Recycling
of receptors
to plasma
membrane
Endosome
Transport
vesicle
Digestive
enzymes
Lysosome
6 Degradation
in lysosome

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