View File - Zarqa University
Transcription
View File - Zarqa University
Zarqa University Faculty: Pharmacy Department: Clinical pharmacy Course title: Clinical biochemistry for pharmacy Instructor: Dr. Inas Almazari Lecture’s time: Mon, Wed (12:30-2:00) Semester: 2nd Semester 2015/2016 Office Hours: week days: 10-11, Mon:11-12 Course description: This course will introduce the different biological samples that can be obtained from patients (for example: blood and urine). Study the clinical aspects of biochemical analysis, and how lab values can be changed in different disease states. Utilization of laboratory findings in the diagnosis, treatment, and prognosis of different diseases will be discussed. Aims of the course: At the end of this course, the student will be introduced to: 1. The principles of laboratory tests and their use in diagnosis. 2. The normal water and electrolytes balance in our body and the effect of diseases on this balance. 3. The effect of the different diseases on renal function, calcium metabolism, lipid metabolism, amino acids and proteins, liver function and carbohydrate metabolism. Intended Learning Outcomes: (ILOs) A. Knowledge and Understanding A1. Concepts and Theories: 1. Explain the molecular basis of different diseases. 2. Determine the disease and its condition according to the required lab analysis. 3. Relate the changes in blood cells such as: count, shape, concentration; to some disease conditions. A2. Contemporary Trends, Problems and Research: Interpret laboratory findings preformed in clinical practice. A3. Professional Responsibility: Relate the signs and symptoms to the molecular basis of the diseases. B. Subject-specific skills B1. Problem solving skills: Develop the ability to relate the laboratory test results to the signs and symptoms to determine the pathological condition of the patient. B2. Modeling and Design: Analyze the test results and determine the required test accordingly B3. Application of Methods and Tools: Determine the best test, method of analysis, choice of the sample to be tested (urine, blood, plasma, sweat, etc.) C. Critical-Thinking Skills C1. Analytic skills: Assess Analyze the laboratory results with different units and extract other parameters from one data. ZU/QP07F018 01 :اإلصدار 2015 حزيران24 :تاريخ اإلصدار Develop the skills of information management. C2. Strategic Thinking: 1. Relate the changes in water and electrolytes balance, hydrogen ion homoeostasis and blood gases to different diseases. 2. Relate the changes in liver function tests to liver diseases. 3. Relate the changes in carbohydrate metabolism, plasma proteins, lipids and lipoproteins to some diseases. 4. To relate the changes in calcium metabolism to renal and bone diseases. C3. Creative thinking and innovation: Determine the further laboratory tests needed for a patient and relate the results to the condition of the patient. Analyze the results and connect the symptoms to the lab tests to determine the disease, its prognosis, and the best treatment D. General and Transferable Skills (other skills relevant to employability and personal development) D1. Communication: Communicate effectively with the medical team concerning the use of laboratory tests in the diagnosis of diseases. D2. Teamwork and Leadership: Work in groups for case study analysis and solving. Course structures: Credit Week Hours 1 1. 2. + 3. 4 4. + 5. 4 6. 3 7. 3 ILOs Topics A1, B1, B2 Introduction and specimen collection Blood and urine collection, factors affecting analyte determinations A3,B3, Water, electrolytes C2 Water, sodium and potassium balance A1, B3, Acid-base disturbances C1 buffers, metabolic and respiratory acidosis and alkalosis B2, C2 Investigation of renal function Acute and chronic renal failure, renal calculi B2, C2, Disorders of carbohydrate D2 metabolism Tests used to diagnose and ZU/QP07F018 Teaching Procedure Lecture with power point Assessment methods Homework Lecturing with power point Homework , Quiz Lecturing, discussion 1st exam (20 points) Lecturing, discussion Homework Lecturing, discussion Case study, Quiz 01 :اإلصدار 2015 حزيران24 :تاريخ اإلصدار 8. + 9. 6 10. + 11. 5 12. + 13. 6 14. 3 15. 1 16. manage diabetes mellitus Lecturing, short Liver function and diseases movie, discussion Liver function tests and their relations to liver diseases A3, B3, Calcium metabolism Lecturing, problem C2, D2 solving Calcium regulation, hypoand hypercalcemia A1, B2, Amino acids and plasma Lecturing, problem C2 solving proteins Aminoacidurea, albumin and immunoglobulins A1, C1, Hematology Lecturing, short D2 movie, discussion Hemoglobin and hemoglobinopathies Lecturing, Revision discussion Lecturing, Final Exam Week discussion A1, B2, C2, D1 Case study 2nd exam (20 points) Homework Case study, Quiz Final Exam (50 points) References: A. Main Textbook: An Illustrated Colour Text in Clinical Biochemistry, 5th edition, Gaw A et al. B. Supplementary Textbook(s): Tietz Fundamental of Clinical Chemistry, 5th edition, edited by Burtis C.A. and Ashwood E.R., 2001 Clinical Chemistry in Diagnosis and Treatment, 6th edition, Mayne P.D., 1998 Clinical Chemistry, 5th edition, Marshall W.J., 2004 Assessment Methods: Methods - First Exam - Second Exam Assignments (reports, quizzes, homework, and participation) - Final Examination ZU/QP07F018 Grade 20% 20% 10% Date The 5th week The 10th week To be announced 50% The 16th week 01 :اإلصدار 2015 حزيران24 :تاريخ اإلصدار