View File - Zarqa University

Zarqa University
Faculty: Pharmacy
Department: Clinical pharmacy
Course title: Clinical biochemistry
for pharmacy
Instructor: Dr. Inas Almazari
Lecture’s time: Mon, Wed (12:30-2:00)
Semester: 2nd Semester 2015/2016
Office Hours: week days: 10-11, Mon:11-12
Course description:
This course will introduce the different biological samples that can be obtained from patients (for example:
blood and urine). Study the clinical aspects of biochemical analysis, and how lab values can be changed in
different disease states. Utilization of laboratory findings in the diagnosis, treatment, and prognosis of different
diseases will be discussed.
Aims of the course:
At the end of this course, the student will be introduced to:
1.
The
principles of laboratory tests and their use in diagnosis.
2. The normal water and electrolytes balance in our body and the effect of diseases on this balance.
3. The effect of the different diseases on renal function, calcium metabolism, lipid metabolism, amino
acids and proteins, liver function and carbohydrate metabolism.
Intended Learning Outcomes: (ILOs)
A.
Knowledge and Understanding
A1. Concepts and Theories:
1. Explain the molecular basis of different diseases.
2. Determine the disease and its condition according to the required lab analysis.
3. Relate the changes in blood cells such as: count, shape, concentration; to some disease
conditions.
A2. Contemporary Trends, Problems and Research:
Interpret laboratory findings preformed in clinical practice.
A3. Professional Responsibility:
Relate the signs and symptoms to the molecular basis of the diseases.
B.
Subject-specific skills
B1. Problem solving skills:
Develop the ability to relate the laboratory test results to the signs and symptoms to determine the pathological
condition of the patient.
B2. Modeling and Design:
Analyze the test results and determine the required test accordingly
B3. Application of Methods and Tools:
Determine the best test, method of analysis, choice of the sample to be tested (urine, blood, plasma, sweat, etc.)
C.
Critical-Thinking Skills
C1. Analytic skills: Assess
Analyze the laboratory results with different units and extract other parameters from one data.
ZU/QP07F018
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Develop the skills of information management.
C2. Strategic Thinking:
1. Relate the changes in water and electrolytes balance, hydrogen ion homoeostasis and blood gases
to different diseases.
2. Relate the changes in liver function tests to liver diseases.
3. Relate the changes in carbohydrate metabolism, plasma proteins, lipids and lipoproteins to some
diseases.
4. To relate the changes in calcium metabolism to renal and bone diseases.
C3. Creative thinking and innovation:
Determine the further laboratory tests needed for a patient and relate the results to the condition of the patient.
Analyze the results and connect the symptoms to the lab tests to determine the disease, its prognosis, and
the best treatment
D. General and Transferable Skills (other skills relevant to employability and personal
development)
D1. Communication:
Communicate effectively with the medical team concerning the use of laboratory tests in the diagnosis
of diseases.
D2. Teamwork and Leadership:
Work in groups for case study analysis and solving.
Course structures:
Credit
Week
Hours
1
1.
2. + 3.
4
4. + 5.
4
6.
3
7.
3
ILOs
Topics
A1, B1,
B2
Introduction and specimen
collection
Blood and urine collection,
factors
affecting
analyte
determinations
A3,B3, Water, electrolytes
C2
Water, sodium and potassium
balance
A1, B3, Acid-base disturbances
C1
buffers,
metabolic
and
respiratory
acidosis
and
alkalosis
B2, C2 Investigation of renal function
Acute and chronic renal
failure, renal calculi
B2, C2, Disorders
of
carbohydrate
D2
metabolism
Tests used to diagnose and
ZU/QP07F018
Teaching
Procedure
Lecture with power
point
Assessment
methods
Homework
Lecturing with
power point
Homework ,
Quiz
Lecturing,
discussion
1st exam
(20 points)
Lecturing,
discussion
Homework
Lecturing,
discussion
Case study,
Quiz
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2015 ‫ حزيران‬24 :‫تاريخ اإلصدار‬
8. + 9.
6
10. + 11.
5
12. + 13.
6
14.
3
15.
1
16.
manage diabetes mellitus
Lecturing, short
Liver function and diseases
movie,
discussion
Liver function tests and their
relations to liver diseases
A3, B3, Calcium metabolism
Lecturing, problem
C2, D2
solving
Calcium regulation, hypoand hypercalcemia
A1, B2, Amino
acids and plasma Lecturing, problem
C2
solving
proteins
Aminoacidurea, albumin and
immunoglobulins
A1, C1, Hematology
Lecturing, short
D2
movie, discussion
Hemoglobin
and
hemoglobinopathies
Lecturing,
Revision
discussion
Lecturing,
Final Exam Week
discussion
A1, B2,
C2, D1
Case study
2nd exam
(20 points)
Homework
Case study,
Quiz
Final Exam
(50 points)
References:
A.
Main Textbook:
An Illustrated Colour Text in Clinical Biochemistry, 5th edition, Gaw A et al.
B.
Supplementary Textbook(s):
Tietz Fundamental of Clinical Chemistry, 5th edition, edited by Burtis C.A. and Ashwood E.R., 2001
Clinical Chemistry in Diagnosis and Treatment, 6th edition, Mayne P.D., 1998
Clinical Chemistry, 5th edition, Marshall W.J., 2004
Assessment Methods:
Methods
- First Exam
- Second Exam
Assignments
(reports,
quizzes,
homework,
and
participation)
- Final Examination
ZU/QP07F018
Grade
20%
20%
10%
Date
The 5th week
The 10th week
To be announced
50%
The 16th week
01 :‫اإلصدار‬
2015 ‫ حزيران‬24 :‫تاريخ اإلصدار‬