Powerpoint

Transcription

Powerpoint
Liver X Receptor Activation Promotes Polyunsaturated
Fatty Acid Synthesis in MacrophagesSignificance
by Alexis Varin, Charles Thomas, Minako Ishibashi, Louise Ménégaut, Thomas
Gautier, Amalia Trousson, Victoria Bergas, Jean Paul Pais de Barros, Michel Narce,
Jean Marc A. Lobaccaro, Laurent Lagrost, and David Masson
Arterioscler Thromb Vasc Biol
Volume 35(6):1357-1365
May 20, 2015
Copyright © American Heart Association, Inc. All rights reserved.
Impact of liver X receptor agonist treatment on the expression of genes involved in
polyunsaturated fatty acid synthesis in human primary macrophages and monocytes.
Alexis Varin et al. Arterioscler Thromb Vasc Biol.
2015;35:1357-1365
Copyright © American Heart Association, Inc. All rights reserved.
Liver X receptor (LXR) regulates polyunsaturated fatty acid synthesis through direct and sterol
responsive element binding protein-1 (SREBP1)–dependent mechanisms.
Alexis Varin et al. Arterioscler Thromb Vasc Biol.
2015;35:1357-1365
Copyright © American Heart Association, Inc. All rights reserved.
Liver X receptor (LXR) activation modulates the fatty acid composition in human macrophages.
Alexis Varin et al. Arterioscler Thromb Vasc Biol.
2015;35:1357-1365
Copyright © American Heart Association, Inc. All rights reserved.
Liver X receptor (LXR) deficiency alters polyunsaturated fatty acid (PUFA) metabolism in mouse
macrophages.
Alexis Varin et al. Arterioscler Thromb Vasc Biol.
2015;35:1357-1365
Copyright © American Heart Association, Inc. All rights reserved.
Liver X receptor agonist treatment directly promotes n-6 and n-3 polyunsaturated fatty acid
(PUFA) biosynthesis in human macrophages.
Alexis Varin et al. Arterioscler Thromb Vasc Biol.
2015;35:1357-1365
Copyright © American Heart Association, Inc. All rights reserved.
Liver X receptor agonist treatment activate gene involved in polyunsaturated fatty acid (PUFA)
biosynthesis and modulates PUFA composition of atherosclerotic arteries.
Alexis Varin et al. Arterioscler Thromb Vasc Biol.
2015;35:1357-1365
Copyright © American Heart Association, Inc. All rights reserved.
Proposed role for liver X receptors (LXRs) in polyunsaturated fatty acid (PUFA) biosynthesis.
Alexis Varin et al. Arterioscler Thromb Vasc Biol.
2015;35:1357-1365
Copyright © American Heart Association, Inc. All rights reserved.

Similar documents