Nevus Anaemicus =الوحمة فقيرة الدم

Transcription

Nevus Anaemicus =الوحمة فقيرة الدم
‫اﻠدﻢ ﻓﻘﻴرﺔ اﻠوﺤﻤﺔ= ‪Nevus Anaemicus‬‬
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‫اﻠدﻢ ﻓﻘﻴرﺔ اﻠوﺤﻤﺔ= ‪Nevus Anaemicus‬‬
‫‪2/3‬‬
Nevus Anaemicus =‫اﻠدﻢ ﻓﻘﻴرﺔ اﻠوﺤﻤﺔ‬
1 is
Nevus
Anemicus
was
Nevus
macule
catecholamines
first
anemicus
or
described
patch,
with
as
by
abe
shown
resultant
congenital
Vorner
below.
vasoconstriction.
1906.
vascular
The
lesional
anomaly
pallor
Nevus
that
is
anemicus
presents
due
to
aLesions
clinically
localized
isand
an
uncommon
as
hypersensitivity
a
hypopigmented
disorder
to
and
Pathophysiology
Intralesional
histamine
However,
alpha-adrenergic
best
catecholamines.
termed
erythema
fails
amay
injection
pharmacologic
to
induce
blocking
does
of
bradykinin,
the
follow
agent,
anticipated
nevus
an
pilocarpine.
axillary
acetylcholine,
resulting
vasodilatation
sympathetic
These
serotonin,
increased
findings
or
block
erythema
nicotine,
suggest
vascular
or
intradermal
in
that
the
5-hydroxytryptamine,
sensitivity
affected
nevus
injection
anemicus
to
area.
of
the
is
and
studies
endothelial
several
anemicus
that
pharmacologic
may
adhesion
show
best
This
donor
molecule
conclusion
anomalies
termed
site
dominance.
ainduction
pharmacologic
is
are
further
involved
(E
It
also
supported
selectin
and
has
nevus.
further
expression)
been
by
autograft
proposed
supporting
may
exchange
that
be
an
involved,
idea
abnormality
transplantation
that
suggesting
nevus
in
The
prevalence
of
nevus
anemicus
is
not
known,
but
itmacules.
is
not
rare.
Lesions
of
nevus
anemicus
usually
persist
unchanged
throughout
life.
They
are
asymptomatic.
No
racial
predilection
has
been
noted
in
the
literature
for
nevus
anemicus.
Nevus
anemicus
appears
more
frequently
in
females.
nevus
present
as
an
incidental
anemicus
since
birth
finding
typically
may
and
be
grows
on
present
present
skin
with
examination.
at
with
the
birth
an
child.
or
asymptomatic
first
Frequently,
appreciated
pale
the
lesion
in
macule
early
of
childhood.Patients
or
nevus
patch
anemicus
that
has
is
been
with
noted
Clinically,
irregular
multiple
the
asymptomatic.
overlooked.
upper
and
margins
nevus
chest.
Nevus
anemicus
Nevi
that
be
located
may
anemicus
anemicus
be
is
on
ain
surrounded
circumscribed,
any
occur
is
noted
part
more
of
at
by
the
birth
frequently
satellite
rounded,
body,
or
in
but
early
in
oval
most
females
childhood,
or
lesions
linear
pale
although
are
commonly
may
usually
macule
be
itsingle
are
may
or
found
patch
or
be
easily
with
on
frequency
in
patients
usually
with unchanged
throughout
life.
Lesions
occur
with
increased
extensive
and
have
been
observed
in
close
association
.from
Areas
of
nevus
with anemicus
frequently
are
capillary
malformations
of
also
characterized
port-wine
has
been
by
described
vascular
type,
a
in
phenomenon
and
patients
melanocytic
with
attributed
phakomatosis
nevi.
to
somatic
pigmentovascularis,
recombination.
Nevus
a
syndrome
anemicus
Phakomatosis
melanoma.
pigmentovascularis
type
IIa
has
been
associated
with
primary
choroidal
Causes
Nevus
hypersensitivity
anemicus
to
is
catecholamines,
due
topersists
aneurofibromatosis
congenital
leading
anomaly
to
localized
of
the
cutaneous
vasoconstriction.
vasculature
resulting
in
Treatment
Medical
Care
Treatment
appearance
makeup.
generally
of
the
nevus
is
not
anemicus
required
for
lesion
nevus
may
anemicus.
benefit
from
Patients
the
application
troubled
by
of
the
camouflage
cosmetic
Medication
No
therapy
isstain
available
for
nevus
anemicus.
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