Intelligent LabPower

cobas® 8000 modular analyzer series
Intelligent LabPower
The cobas® 8000 modular analyzer series
Because demanding jobs require
intelligent and powerful solutions
The cobas 8000 modular analyzer series is the newest
member of the Roche cobas modular platform family.
The new serum work area (SWA) solution is designed
for high workload laboratories and can cover a
throughput range of 3 -15 million tests/year .
One cobas 8000 modular analyzer series configuration
consists of up to 4 analytical modules and is built with
a core unit, an optional ISE unit (cobas ISE module),
a high throughput clinical chemistry module (cobas c
701 module), a mid volume throughput clinical chemistry
module (cobas c 502 module) and the immunoassay
module (cobas e 602 module).
Combinations of those modules offer more than 19
configurations with many choices to tailor solutions
to individual laboratory needs. On-site expandability
allows for efficient change management.
Many innovative design elements, such as intelligent
sample routing with fast transportation and return
lines, independent processing lines within each module,
the Module Sample Buffer (MSB) in each module, the
tailor-made and harmonized reagent cassette concept
and many more, are further contributions to added
value in the high workload laboratory.
cobas® 8000 modular analyzer series
Intelligent LabPower
There are 5 good reasons why the cobas 8000 modular
•High speed
analyzer series offers a new dimension in productivity,
•Intelligent sample dynamics
efficiency, process innovation and consolidation which are:
•Intelligent workflow management
•Premium quality & safety
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•Multidimensional modularity
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cobas® 8000
modular analyzer series
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Consolidation
The cobas 8000 modular
analyzer series offers a new
dimension of consolidation
for high volume laboratories,
offering real tailor made
solutions, ensuring exceptional consolidation power.
Intelligent LabPower
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Process innovation
The cobas 8000 modular analyzer series
offers a new dimension of process innovation
for high workload laboratories, driving process
and healthcare innovation and enhancing
overall workflow efficiency.
Productivity
The cobas 8000 modular
analyzer series offers a new
dimension of productivity for
high workload laboratories
with many features to ensure
high test throughput per
hour and improved sample
turn around time (TAT).
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Efficiency
The cobas 8000 modular analyzer series
offers a new dimension of efficiency
for high volume laboratories,
contributing to overall cost savings.
cobas® 8000 modular analyzer series
At a glance
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cobas 8000 data manager
• Screen sharing with the analyzer software
and cobas e-services on a single screen for
convenient instrument monitoring.
• Traceability information for easy tracking of
calibration and reagent information offers
more transparency.
• User defined fully automated and selective
rerun and reflex testing.
• Connectivity of up to 3 cobas 8000 modular
analyzer series in a single cobas 8000 data
manager.*
• Technical validation of sample result in combination with rule programming improves and
accelerates the result release process.
• QC management of all connected instruments
on a single screen supports flexible integration of local requirements for QC standards
and rules (e.g. Levey-Jennings plots and
diagrams, Westgard rules,…etc.).
*available post-launch
2
Core Unit
•Loading capacity of 300 samples
(15 racks/tray, 5 samples/rack)
•Throughput of up to 1,000 samples/hour
•Dedicated STAT port
•Optional sample rotation unit
3
cobas ISE module
•Sodium, potassium, chloride
•900 or 1,800 tests/hour
•ISE specific sample probe with clot
detection
•Independent processing line
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4
cobas c 701 module
•Clinical chemistry, homogeneous
immunoassays
•Throughput of up to 2,000 tests/hour
•70 reagent channels
•Specimen integrity via serum indices,
clot and liquid level detection
•Contact free ultrasonic mixing
•Reagent RFID reader
•2 sample probes
•4 reagent probes
•Pipetting cycle time of 1.8 seconds
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6
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cobas c 502 module
•Clinical chemistry, homogeneous immunoassays, HbA1c (whole blood measurement)
•Throughput of up to 600 tests/hour
•60 reagent channels
•Reagent loading on the fly
•Specimen integrity via serum indices,
clot and liquid level detection
•Contact-free ultrasonic mixing
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6
cobas e 602 module
•Heterogeneous immunoassays
•Throughput of up to 170 tests/hour
•25 reagent channels
•Carryover-free disposable tips
•Clot and air bubble detection
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Module Sample Buffer (MSB)
•Capacity for 20 sample racks; additional
capacity of 100 samples per module
•Environmental controlled compartment
for 5 Auto QC racks
•Backup operation port
•Switch gates for short cuts; gripper for
moving the racks from line to line
•Random access for the racks; racks can go
from everywhere to everywhere
The very compact design of the cobas 8000 modular
analyzer series guarantees highly productive outcome
of reportable results per invested space and budget.
Intelligent LabPower
With a passion for productivity
The cobas 8000 modular analyzer series offers a new
dimension of productivity because of its high speed
pipetting, fast rack transport, intelligent sample routing
due to the unique Module Sample Buffer in each module
and automated rerun and reflex testing.
•Delivers the throughput per hour
•Manages peak times efficiently
•Increases sample capacity on board
•Improves sample turn around time and availability
The highly automated, reliable and innovative design
of the cobas 8000 modular analyzer series results in
a high number of reportable results per full time
equivalent and/or expenses contributing to overall
cost savings.
Intelligent LabPower
With a passion for efficiency
The cobas 8000 modular analyzer series offers a new
dimension of efficiency because of reliable hardware
built, high quality results, many back-up options, many
automated processes (e.g. AutoQC, cobas e-services)
and a convenient tailor-made reagent cassette concept.
• Maximizes walk-away time
• Reduces hands on time
• Optimizes cost management
• Improves sample turn around time and availability
Many innovative design and process elements in the
cobas 8000 modular analyzer series not only streamline
the overall workflow process in the system but also
enhance the overall workflow efficiency for the
laboratory and its environment.
Intelligent LabPower
With a passion for
process innovation
The cobas 8000 modular analyzer series offers a
new dimension of process innovation because of the
unique Module Sample Buffer (MSB) at each module,
with switch gates to flexibly optimize sample routing,
Auto QC concept, connectivity to pre-analytical units...
and many more.
•Ensures unrestricted rack traffic flow for intelligent
sample routing
•Optimizes workflow
•Maximizes walk away time
•Provides confidence in results
Many options in analytical modules, reagent channels,
parameter menu, cassette size and STAT management
contribute to the exceptional consolidation power in
the cobas 8000 modular analyzer series.
Intelligent LabPower
With a passion for consolidation
The cobas 8000 modular analyzer series offers a new
dimension of consolidation because of its highly scalable design resulting in more than 19 configurations,
up to 270 reagent channels and because of more than
116 clinical chemistry parameters and more than 77
immunoassays.
Some examples from the possible configurations
9,000
Throughput tests/hour with ISE
8,000
7,000
6,000
•real tailor-made solutions for every lab and highly
efficient change management
•maximizes throughput and consolidation power
without compromising workflow
•consolidates very frequently requested tests with less
frequently requested test
5,000
4,000
3,000
2,000
1,000
0
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50
100
150
Reagent channels
200
250
Because demanding jobs require intelligent
and powerful solutions, now and in the future.
Intelligent LabPower
with a passion for uniqueness
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The cobas 8000 modular analyzer series with its flexible
modularity offers tailored solutions to meet the changing
laboratory needs, bringing a new dimension in terms of
productivity, efficiency and consolidation.
The cobas 8000 modular analyzer series acts intelligently,
empowering the laboratory to improve customer and
patient services.
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The cobas 8000 modular analyzer series provides intelligent
solutions for demanding jobs. Designed for high-volume
testing, the cobas 8000 modular analyzer series reaches
new dimensions in high speed, intelligent sample dynamics
and workflow improvements whilst still ensuring optimal
performance for the individual patient. Highest quality and
safety standards are met and intelligent sample, reagent
and result management further enhances efficiency.
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Intelligent LabPower
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cobas® 8000
modular analyzer series
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©2009 Roche
Roche Diagnostics Ltd.
CH-6343 Rotkreuz
Switzerland
www.roche.com
05642213001b➀0709 - 1.5 WW
COBAS, COBAS C, COBAS E
and LIFE NEEDS ANSWERS
are trademarks of Roche.
cobas® 8000 modular analyzer series
Parameter overview
Clinical chemistry
cobas c 701 and cobas c 502 modules
Enzymes
cobas c 701
Acid Phosphatase
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ALP IFCC
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ALT IFCC
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ALT IFCC pyridoxal phosphate
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Amylase total, serum, urine
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Amylase pancreatic, serum, urine
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AST IFCC
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AST IFCC pyridoxal phosphate
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CHE Acetyl
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CHE Butyryl
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CHE Dibucaine
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CK-NAC
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CK-MB
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GGT IFCC/Szasz
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GLDH
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HBDH
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LDH IFCC
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LDH opt
Lipase
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Substrates
Albumin BCG
Albumin BCP
Ammonia
Bicarbonate
Bilirubin direct
Bilirubin total
Calcium, serum, urine
Cholesterol
Cholesterol HDL
Cholesterol LDL
Crea Jaffé, serum, urine
Crea PAP, serum, urine
Fructosamine
Glucose, serum, urine, CSF
Glucose, hemolysate
Iron
Lactate, plasma, CSF
Magnesium, serum, urine
Phosphate, serum, urine
Total Protein, serum
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cobas c 502
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Clinical chemistry
cobas c 701 and cobas c 502 modules
Substrates
cobas c 701
Total Protein, urine
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Total Protein, CSF
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Triglycerides
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Triglycerides (glycerol blanked)
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UIBC
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Urea/BUN, serum, urine
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Uric Acid, serum, urine
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Specific proteins
a1 Acid Glycoprotein
a1 Antitrypsin
a1 Microglobulin
Albumin, TQ, serum, urine
Albumin, TQ, CSF
Apo A1
Apo B
AT
b2-Microglobulin
ASLO
C3c
C4
Ceruloplasmin
CRP
CRP high sensitive
Cystatin C
D-Dimer
Ferritin
Haptoglobin
HbA1c, hemolysate
HbA1c, whole blood
IgA
IgG
IgM
Kappa
Lamda
Lp(a)
Myoglobin
Prealbumin
RF II
sTfR
Transferrin
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cobas c 502
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cobas® 8000 modular analyzer series
Parameter overview
Clinical chemistry
cobas c 701 and cobas c 502 modules
TDM
cobas c 701
Acetaminophen
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Amikacin
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Carbamazepine
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Cyclosporine A
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Digitoxin
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Digoxin
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Gentamycin
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Lidocaine
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Lithium
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MPA total
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NAPA
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Phenobarbital
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Phenytoin
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Procainamide
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Quinidine
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Salicylate
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Theophylline
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Tobramycin
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Valproic Acid
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Vancomycin
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DATs
Amphetamines
Barbiturates
Benzodiazepines
Cocaine
EDDP
Ethanol, serum, urine
LSD
Methadone
Methaqualone
Opiate
Oxycodone
PCP
Propoxyphene
THC
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Thyroid
T4
T-Uptake
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ISE
Chloride
Potassium
Sodium
cobas c 502
cobas ISE
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COBAS, COBAS C, COBAS E and LIFE NEEDS ANSWERS
are trademarks of Roche.
©2009 Roche
Roche Diagnostics Ltd.
CH-6343 Rotkreuz
Switzerland
www.roche.com
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Immunochemistry
cobas e 602 module
Anemia
Ferritin
Folate
RBC Folate
Vitamin B12
Bone markers
b-CrossLaps
Intact PTH
N-MID Osteocalcin
P1NP
Vitamin D3 (25-OH)
Cardiac
CK-MB (mass)
Digoxin
Digitoxin
Myoglobin
NT-proBNP
Troponin I
Troponin T 4th gen.
Troponin T hs
Fertility/hormones
ACTH
C-Peptide
Cortisol
DHEA-S
Estradiol
FSH
hCG +b
Insulin
LH
Progesterone
Prolactin
SHBG
Testosterone
Maternal care
AFP
free b hCG **
hCG +b
PAPP-A
PIGF
sFLT-1
TORCH
CMV IgG
CMV IgM
Rubella IgG
Rubella IgM
Toxo IgG
Toxo IgM
Infectious
diseases
Anti-HAV IgM
Anti-HAV total
Anti-HBc
Anti-HBc IgM
Anti-HBe
Anti-HBs
Anti-HCV
HBeAg
HBsAg
HbsAg confirmatory
HIV Antigen
HIV Antigen
confirmatory
HIV combi
Tumor markers
AFP
CA 125
CA 15-3
CA 19-9
CA 72-4
CEA
Cyfra 21-1
free PSA
hCG +b
NSE
S 100
total PSA
Thyroid function
Anti-Tg
Anti-TPO
Anti-TSH receptor
FT3
FT4
T3
T4
Tg
Tg confirmatory kit
TSH
T-Uptake
Note:
* Post-launch menu
** only in selected markets
Last review July 2009
Critical care
BRAHMS PCT
IL6
S100
Rheumatoid
arthritis
Anti-CCP
Others
IgE
cobas® 8000 modular analyzer series
Technical specifications
System
Modular, analytical system platform, consolidated work area for Clinical Chemistry and
Immunochemistry, expandable and re-configurable on site
Types of modules
cobas
cobas
cobas
cobas
Number of module combinations
More than 19 module combinations (up to 4 modules in one core unit)
Up to 8 combinations with photometric modules
Up to 4 combinations with HetIA modules
Up to 10 combinations with photometric and HetIA modules
Sample throughput
Up to 200 racks/hour
or 1,000 samples/hour
Test throughput
(theoretical max)
170 up to 8,400 tests/hour
3,500 up to 8,400 tests/hour with photometric & ISE modules
170 up to 680 tests/hour with HetIA modules
3,670 up to 7,970 tests/hour with photometric and HetIA modules
Number of reagent channels
(reagent slots)
25 up to 270 reagent channels (reagent slots):
3 channels on cobas ISE module
70 reagent channels on cobas c 701 module
60 reagent channels on cobas c 502 module
25 reagent channels on cobas e 602 module
Programmable parameters
314 with photometric and HetIA modules
200 photometric tests, 3 ISE tests, 8 formulas, 3 serum indices with photometric modules
100 heterogeneous tests with cobas e 602 modules
Sample material
Serum, plasma, urine, CSF, supernatant
Core unit analytics
Load/unload capacity: Rack:
Rack types:
Tray:
STAT port:
Sample container types
Primary tubes: 5 to 10 ml; 16 x 100, 16 x 75, 13 x 100, 13 x 75 mm
Hitachi Sample cup: 2.5 ml
Hitachi Micro cup: 1.5 ml, (exception: cobas e 602 module)
Cups on tube: Cup/Micro cup on top of a 16 x 75/100 mm tube
Non standard tube: False bottom tube or ø 11 – 13 tubes, with lengths of 63 – 102 mm
(ø 11 – 13 tubes are available only for cobas c 502 module)
Cups on non standard tube: Cup/Micro cup on top of a non standard tube
ISE module: c 701 module: c 502 module:
e 602 module: Electrolyte measuring unit
Photometric measuring unit
Photometric measuring unit
ECL technology measuring unit
300 samples for each
5 position rack, RD standard rack
Routine, STAT, Control, Calibrator, Rerun (manual), Wash
Tray with 15 racks/75 samples, RD standard tray
STAT samples are processed with priority
cobas® 8000 modular analyzer series
Technical specifications
Sample volume
1.5 – 35 μl
Sample dilution
3 – 121 times
Sample clot detection
Available for cobas ISE, cobas c 701, cobas c 502, cobas e 602 modules
Sample air bubble detection
Available for cobas e 602 module
Sample storage capacity
12,000 sample data sets (as a total for routine, STAT and control samples)
Rerun/reflex function
Automatic rerun and manual rerun
Automatic reflex is supported by the system, reflex request to be provided by
cobas 8000 data manager
Electrical requirements
Main AC voltage:
Global 16A, 3 x 230V + N + G
USA 40A, 1 x 208V + N + G
Power requirements:
1 kVA (core unit)
0.5 kVA (cobas ISE module)
3 kVA (cobas c 701 module)
2 kVA (cobas c 502 module)
2 kVA (cobas e 602 module)
Frequency: 50/60 Hz ± 0.5 %
Regulatory requirements
CE, us/cETL, CB Test Certificate
The instrument also complies to EMC standard IEC 61326-2-6
Operating conditions
Ambient temperature: 18 – 32 °C
Ambient humidity: 30 – 85 %
Physical dimensions
Core Unit: 102 cm (width), 114 cm (depth)
cobas c 701 module
(incl. Module Sample Buffer): 150 cm (width), 114 cm (depth)
cobas c 502 module
(incl. Module Sample Buffer): 150 cm (width), 114 cm (depth)
cobas e 602 module
(incl. Module Sample Buffer): 150 cm (width), 104 cm (depth)
cobas ISE module: 45 cm (width), 114 cm (depth)
Weight
cobas ISE module: approx. 30 kg
cobas c 701 module
(incl. Module Sample Buffer): approx. 580 kg
cobas c 502 module
(incl. Module Sample Buffer): approx. 380 kg
cobas e 602 module
(incl. Module Sample Buffer): approx. 410 kg
Core Unit: approx. 480 kg
Control Unit: approx. 75 kg
COBAS, COBAS C, COBAS E
and LIFE NEEDS ANSWERS
are trademarks of Roche.
©2009 Roche
Roche Diagnostics Ltd.
CH-6343 Rotkreuz
Switzerland
www.roche.com