faculty of biology - Universitatea „Alexandru Ioan Cuza”

Transcription

„ALEXANDRU IOAN CUZA” UNIVERSITY
IASI
FACULTY OF BIOLOGY
GUIDE OF MASTER DEGREE STUDIES
2009
COORDINATORS: READER PROFESSOR, PhD CARMEN GACHE,
and CHIEF SECRETARY Mihaela-Tatiana BUCSA
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I. GENERAL INFORMATION REGARDING THE FACULTY
THE FACULTY' S ADDRESS
SHORT HISTORY
MISSION
SPECIALIZATIONS
ADMINISTRATIVE STRUCTURES
THE FACULTY' S BOARD
SECRETARY' S OFFICE
ACADEMIC CALENDAR
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THE FACULTY' S ADDRESS
CAROL I Avenue, no. 11A
Postal Code 700506
IASI
ROMANIA
TEL.: 0232 201 072
FAX : 0232 201 472
SHORT HISTORY
The Faculty of Biology was founded in 1860, at the same time with "Alexandru Ioan
Cuza” University from Iasi, as a department of the Faculty of Sciences (Physics,
Mathematics and Natural Sciences). Years later, in 1948, the Department of Natural
Sciences became the Faculty of Natural Sciences, within which operate several departments
(Botany, Zoology, Vegetal Physiology, Animal Physiology and Geology).
In 1959, the professors teaching Biological sciences joined hands with the professors
teaching Geographical sciences and together they ground the Faculty of Natural Sciences –
Geography, which becomes, in 1963, the Faculty of Biology - Geography. In 1977 due to the
development of the Department of Geology, the Faculty completes its name within the field of
Natural Sciences' studies, becoming the Faculty of Biology - Geography - Geology.
In 1990, the Faculty of Biology is founded and beginning with 2008, it disposes of three
professional laboratories:
- Professional Laboratory of Vegetal Biology;
- Professional Laboratory Animal Biology;
- Professional Laboratory of Biochemistry and Molecular Biology.
The Faculty of Biology within "Alexandru Ioan Cuza" University functions as a public
institution, according to the Constitution of Romania and the Education Law no. 84/1995.
The Faculty of Biology receives its funds from the state budget, nevertheless, at the
same time, it has its own funds, obtained and used under the conditions of university
autonomy.
MISSION
Entering the development of the Romanian school of Biology, promoting the universal
values of the living world, taking part in the environmental and socio – economic challenges
of the contemporary world, the Faculty of Biology within “Al. I. Cuza” University from Iasi
assumes the following didactic, scientific and educational mission:
- to provide initial and continuous training of specialists (also recognized on the European/
international labour market) for areas of teaching and scientific research, specialists who will
work as: teachers of biology, biochemistry, ecology, researchers in various research
institutes, biologists in the pharmaceutical and food industry, sanitary and agricultural units,
in agencies for environmental protection, Botanyal gardens, parks and natural reservations,
museums of natural sciences;
- the assertion of the research and teaching activities in biology in Iasi, into the national,
European and international area of science and education;
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- the implementation of principles and values of bioethics, education for environmental
protection and sustainable development.
The mission of the Faculty of Biology also contributes to the shaping of “Al. I. Cuza”
University’s mission. Thus, the Faculty of Biology proposes to virtually contribute to the
creation of cultural and social values, along with the means needed for this accomplishment,
but also contributes to the promotion of scientific research and integration of its results into
the world patrimony of values.
For the achievement of the Faculty’s mission, a series of objectives and means are
taken into consideration and the synchronization of the Romanian university education with
the European one represents a priority.
The main purpose of the faculty is to train specialists who will work in the preacademic and academic education field, in scientific research and in other fields of activity
(social, cultural, production etc.) The Faculty must be an institution of excellence, with general
orientation in biology, which ensures at didactic and scientific level the continuous knowledge
and sustainable administration of biological resources, the founding of biotechnologies, etc.
The formulation and application of a European integration strategy is
accomplished within the context of joined “dynamic tradition” in the field, with a constant
preoccupation with modernization, both in the instructive-educating process, as well as in the
formation and continuous support of some schools and certain directions in scientific research.
The direction of the didactic and scientific activities
The main coordinates of the direction of these activities are represented by the increase
of professional competence of the teaching staff and the answer to continuous changes of
social demand. Based on these coordinates, we aim at achieving continuous improvement of
the graduates’ qualification parameters adapted to the new social and economic conditions
within the context of the development of our country, such as:
9 Improvement of the professional training level;
9 An education system that can ensure the ability of the youth to adapt to the new socioeconomic demands;
9 Stimulation of personal initiative;
9 Ensuring professional mobility.
9 Stimulation of continuous self–training.
SPECIALIZATIONS
On the grounds of Governmental Decision 410/2002 regarding the academic
structures and specializations having temporary approval or authorization for functioning in
high education institutions, with the subsequent adjustments and changes, at the Faculty of
Biology are held the following curricula:
A. University Studies ending with bachelor’s degree
(6 semesters’ duration, 180 ECTS credits, full time courses)
Field
Biology
Environmental science
Specialization
Biology (full time courses)
Biochemistry (full time courses)
Ecology and Environmental Protection (full time
courses)
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B. University Studies ending with bachelor’s degree
(6 semesters’ duration, 180 ECTS credits, distance courses)
Field
Specialization
Biology
Environmental science
Biology (distance courses)
Ecology and Environmental Protection (distance
courses)
C. Master Studies (4 semesters’ duration, 120 ECTS credits, full time courses)
Field
Specialization
Biology
Environmental
science
Biodiversity and productivity of Ecosystems (full time
courses)
Microbial and Cellular Biotechnologies (full time courses)
Molecular Genetics (full time courses)
Bio-procedures in agro-alimentary field (full time courses)
Bio-anthropology (full time courses)
Development Biology (full time courses)
Environmental Counseling (full time courses)
Ecological education for sustainable development (full time
courses)
D. Doctoral School (2 semesters’ duration, 60 ECTS credits).
In order to ensure an efficient didactic and research activity, the Faculty of Biology is
structured, at administrative level, on three Professional Laboratories having different uses,
which cover the main directions of education in biology:
9 Professional Laboratory of Vegetal Biology;
9 Professional Laboratory of Zoology – Ecology;
9 Professional Laboratory of Molecular and Experimental Biology.
THE PROFESSIONAL LABORATORY OF VEGETAL BIOLOGY
Gathers professors specialized in the field of morpho-anatomy and vegetal cytology,
systematic botany, physiology, biogeography, protection of plants and other related fields.
Main Research Directions
9 Research on vegetal taxonomy and preservation of biodiversity
9 Introducing, adjusting and closely watching the naturalization in „Anastasie Fatu”
Botanyal Garden, Iasi, of rare and protected plants of the Romanian flora
9 Research on the multiplication by traditional methods and „in vitro” cultivation of rare
and vulnerable plants of the Romanian flora
9 Morpho – anatomic study of medical plant species
9 The influence of pesticides and atmospheric pollutants on the structure of cultivated
and spontaneous plants
9 The study of embryogenesis process on forest species
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9 Compared anatomy of vegetal organs on different species from collections of
ornamental plants cultivated in „Anastasie Fatu” Botanyal Garden of Iasi.
9 Histo-anatomical and physiological changes on plants cultivated under stress
conditions. The study of stationary conditions and favorable or restrictive factors on
the diversity of fungi.
9 Evaluation of pollution’s impact on species diversity of mycorisant fungi
9 Important areas of plant protection in Romania.
Staff
Professor Maria Magdalena ZAMFIRACHE, Ph. D. [email protected]
Professor Catalin TANASE, Ph. D.
Reader Professor Lacramioara IVANESCU, Ph. D.
Reader Professor COSTICA, Ph. D.
Reader Professor Smaranda VANTU, Ph. D.
Reader Professor Irina GOSTIN, Ph. D.
Lecturer Mihai COSTICA, Ph. D.
Lecturer Anisoara STRATU, Ph. D.
Lecturer Oana ZAMFIRESCU, Ph. D.
Lecturer Ciprian MANZU, Ph. D.
Assistant Professor Bogdan SURUBARU, Ph. D. student
Assistant Professor Vasilica CHINAN, Ph. D.
Laboratory Assistant Ramona Crina GALES, Ph. D.
Counseling Professors:
Professor Constantin TOMA, Ph. D. – correspondent member of the Academy, Doctorate
Coordinator
Associated Teaching Staff:
Professor Toader CHIFU Ph. D. – Doctorate Coordinator
Professor Mihai MITITIUC Ph. D. – Doctorate Coordinator
Professor Nicolae STEFAN, Ph. D.
Professor Alexandrina MURARIU, Ph. D.
PROFESSIONAL LABORATORY OF ZOOLOGY – ECOLOGY
Gather specialists from all the fields of invertebrate and vertebrate zoology,
ornithology, entomology, parasitology, terrestrial and aquatic ecology, hydrobiology, marine
biology, evolutionism, environmental legislation, paleontology, histoembryology, animals,
embryology, compared anatomy and archaeozoology etc.
9 Monitoring the biodiversity of terrestrial and aquatic ecosystems, natural or manmade
9 Studies on the present state of protected areas and natural reservations
9 The study of the parasitoid complexes of various pestilence insects in forest
ecosystems and agro-ecosystems
9 Studies on the taxonomy of various groups of invertebrates
9 Studies on the ecology and ethology of various groups of vertebrates
9 Archaeozoology research regarding prehistoric and historic civilizations spread in the
East Carpathian area
9 Research of osteometry on mammals from the superior Pleistocen and Holocen
9 Research on ecological morphology regarding certain species of animals having the
value of bioindicators.
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Staff
Professor Ion MOGLAN, Ph. D. [email protected]
Professor Mircea NICOARA, Ph. D.
Reader Professor Mariana MUSTATA, Ph. D.
Reader Professor Luminita BEJENARU, Ph. D.
Reader Professor Ion COJOCARU, Ph. D.
Reader Professor Carmen GACHE, Ph. D.
Reader Professor Stefan ZAMFIRESCU, Ph. D.
Reader Professor Victor SURUGIU, Ph. D.
Lecturer Irinel POPESCU, Ph. D.
Lecturer Simina STANC, Ph. D.
Lecturer Anca-Narcisa NEAGU, Ph. D.
Lecturer Constantin ION, Ph. D.
Lecturer Mircea MITROIU, Ph. D.
Lecturer Vasile SIRBU, Ph. D.
Lecturer Ovidiu POPOVICI, Ph. D.
Assistant Professor Gabriel PLAVAN, Ph. D. student
Professor Iordache ION, Ph. D. – Doctorate Coordinator
Professor Gheorghe MUSTATA, Ph. D. – Doctorate Coordinator
Related Teaching Staff:
Professor Constantin PISICA Ph. D. – Doctorate Coordinator
Professor Ionel MIRON, Ph. D. – Doctorate Coordinator
Professor Ionel ANDRIESCU, Ph. D. – Doctorate Coordinator
PROFESSIONAL LABORATORY OF MOLECULAR AND EXPERIMENTAL BIOLOGY
Based on top approach of contemporary biology, the department reunites teaching
staff with a wide experience in the field of plant, animal and micro-organisms genetics,
human genetics, biochemistry of animals, plants and micro-organisms, medical microbiology,
microbial biotechnologies, cellular and molecular biology, biophysics, physiology of animals,
which complement the descriptive classical fields of animal and vegetal biology, contributing
to the enrichment of the national, European and universal scientific patrimony.
9 Vegetal cytogenetics and molecular genetics research on plant species which are of
economic interest and represent rare or protected flora
9 Molecular genetics researches regarding the taxonomy of some fish species of
economic interest
9 Genetic studies of eukaryote microorganisms
9 Biological activity of some ecophysiologic groups of bacteria involved in the carbon
circuit from several surface waters and soil types from Moldavia
9 Research on the capacity of regeneration and bio-productivity of vegetal and
microbial cells
9 Biotechnological use of the skim milk resulted from cheese making with the purpose
of obtaining levurian biomass
9 The study of biochemical components and metabolism processes in living organisms,
animals and plants, under normal and pathological conditions
9 The interaction of neurotransmitters in the processes of learning and memorizing
9 The action of some synthesis or semi-synthesis bio-products and of some vegetal
extracts of normal and tumor cells
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9 The change of some physiological parameters of the human organism by using
kinesis therapy methods and being under the influence of physical effort
9 Comparative studies of genotype made by using bandaging methods
9 The influence of electromagnetic radiations on normal or pathological cell processes
9 The study of specific actions of some bio-products on animal cells at membrane and
metabolic level
9 Phylogenetic studies on hymenoptera by using cell and molecular biology methods
9 Comparative studies on total and mitochondrial DNA content on fish
9 Researches on the eco-physiology of nutrition on young and reproductive breading
species of fish (crap, African catfish and others)
9 Hematological studies on fish belonging to pisciculture environments under normal
and stress conditions.
Staff
Professor Dumitru COJOCARU, Ph. D. [email protected]
Professor Costica MISAILA, Ph. D.
Professor Ovidiu TOMA, Ph. D.
Lecturer Simona-Isabela DUNCA, Ph. D.
Lecturer Zenovia OLTEANU, Ph. D.
Lecturer Anca HUMA, Ph. D.
Lecturer Cristian-Sorin CIMPEANU, Ph. D.
Lecturer Mirela-Mihaela CIMPEANU, Ph. D.
Lecturer Cristian TUDOSE, Ph. D.
Lecturer Iulia-Csilla BARA, Ph. D.
Lecturer Elena CIORNEA, Ph. D.
Lecturer Lucian HRITCU, Ph. D.
Lecturer Lucian GORGAN, Ph. D.
Lecturer Marius STEFAN, Ph. D.
Lecturer Lacramioara OPRICA, Ph. D.
Lecturer Calin-Lucian MANIU, Ph. D. student
Lecturer Eugen UNGUREANU, Ph. D. student
Assistant Lucian FUSU, Ph. D.
Assistant VASILE, Ph. D.
Assistant MIHASAN, Ph. D.
Assistant Sabina COJOCARU, Ph. D student
Professor Vlad ARTENIE Ph. D. – Doctorate Coordinator
Related Teaching Staff:
Professor Octavita AILIESEI Ph. D. – Doctorate Coordinator
Professor Erika-Maria NIMITAN, Ph. D.
Professor Ion NEACSU, Ph. D.
FACULTY’S BOARD
Acting on the grounds of the present legislative background, the Faculty of Biology
carries out its activity on the grounds of: legislative norms in force, the principles of the
University Book, regulations made by the Board of “AL. I. Cuza” University from Iasi and the
decisions taken by the leading board of the Faculty of Biology.
The decisions taken by the board of the Faculty observe the legislation in force,
based on the provisions of the Romanian Constitution and Education Law.
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All activities carried out observe the norms established by: the Regulation regarding
the didactic activity, the Regulation regarding the boarding, evaluation and promotion of
teaching and research staff, the Regulation regarding the organizing and fulfilling the steps of
the Doctorate, the Regulation regarding the conferring of the honorary titles, Norms for
administration and management of the patrimony, the Deontological Code of the academic
community members, the Regulation for the grounding and functioning of the Senate and the
Councils of the Faculties.
University’s Leading Board is made up of the Council of Faculty and the Office of
the Council of Faculty.
The Management Main Board is made up of: one position of Dean, three positions
of Department Directors, two positions of Pro-dean, one position of Chancellor, and one
position of Faculty’s Chief Administrator.
Position held
Dean
Director of Biology Department
Director of Research Department
Coordinator of ID Department
Pro-dean (I)
Pro-dean (II)
Faculty’s Chancellor
Faculty’s Chief Administrator
Didactic position held , Surname and Name
Univ. Professor Ioan Moglan, Ph. D.
Univ. Professor Maria Magdalena Zamfirache, Ph. D.
Univ. Lecturer Zenovia Olteanu, Ph. D.
Univ. Lecturer Carmen Gache, Ph. D.
Univ. Professor Dumitru Cojocaru, Ph. D.
Univ. Lecturer Luminita Bejenaru, Ph. D.
Univ. Lecturer Lacramioara Ivanescu, Ph. D.
Ec. Eng. Cecilia Bilba
The Management Main Board of the Faculty of Biology
The Pro-deans have the following attributions:
- Pro-dean I, responsible for the scientific research activity;
- Pro-dean II, responsible for didactic activities and student issues;
The Dean or another member of the academic staff of the faculty, designated by him,
represents the Faculty of Biology at national and international university institutions.
The Council of the Faculty of Biology represents the highest leading authority
within the Faculty of Biology. The President of the Council of the Faculty is the Dean.
Reunited periodically (every two months), the Council of the faculty issues decisions and
approves regulations which are subjected to analysis and validation (according to each case)
from the Academic College, the Office of the Senate or the University’s Senate, decisions
which become compulsory for all academic community members of the faculty.
18 members take part in the Council of the Faculty of Biology: 13 teaching staff
members, 4 students and the Faculty’s Chief Administrator.
The Office of the Council of the Faculty ensures the caring out of the current
activities and also the fulfilment of the decisions of the Senate, the Academic College and the
Faculty’s Council. The office of the Faculty is normally reunited weekly, and it is made up 6
members: the Dean, the Director of the Biology Department, 2 Pro-deans, Chancellor of the
Faculty and the Faculty’s Chief Administrator.
Department Director
Professor Maria Magdalena Zamfirache, Ph. D., telephone 201513, B 445 cabinet (1st
floor, Vegetal Biology Section) [email protected]
Dean
Professor Ioan Moglan, Ph. D., tf. 201565, B 375 cabinet (ground floor, Zoology
Section), ECTS Department coordinator [email protected]
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ID Department Coordonator
Reader Professor Carmen Gache, Ph. D., telephone 201472, cabinet B 369 (ground
floor, Zoology Section), [email protected]
Pro-dean responsible with student issues
Reader Professor Luminta Bejenaru, Ph. D., telephone 201567, cabinet B 209 (1st
semi-basement, Anatomy and animal histology Section), [email protected]
Pro-dean responsible with research activity
Professor Dumitru Cojocaru, Ph. D., telephone 201645, cabinet B 227 (I semibasement, Biochemistry Section), [email protected]
Chancellor
Reader Professor Lacramioara Ivanescu, Ph. D., telephone 201510, cabinet B 443 (I
floor, Vegetal Biology Section), [email protected]
Faculty’s Chief Administrator
Cecilia Elena Bilba, program: Monday - Thursday, 10 a.m. -2 p.m.
Responsibilities: Faculty’s budget, scholarships, boarding, camps, taxes, practical
training, students´ records, field applications, norms, didactic responsibilities, crossed
payments, various reports, travel orders, inventory, check sheets and attendance sheets,
public relations.
Telephone 0232-201072; Fax: 0232-201472
E-mail: [email protected]
RESPONSIBLE WITH THE SOCRATES PROGRAM
Professor Mircea-Nicusor Nicoara, Ph. D., B 376 cabinet (ground floor, Zoology
Section), [email protected];
RESPONSIBLE WITH THE WEB SITE OF THE FACULTY
Lecturer, Calin Maniu, Ph.D. student; 122-K cabinet (B Building, semi-basement II,
Biophysics Section), [email protected]
SECRETARIAT
Chief Secretary:
Mihaela-Tatiana BUCSA
Responsibilities: new registrations, expulsions, promotions, research, contests, Socrates,
doctorate, certificates, archive, academic direction, Gesco, public relations.
Tel.: 0232-201072; Fax: 0232-201472
Secretaries:
Gabriela-Cristina BUSUIOC
Responsibilities: development, various certificates, academic direction, public relations,
academic records.
Tel.: 0232-201072; Fax: 0232-201472
Oana-Elena BABEI
Responsibilities: cashing taxes, inventory, archive, mailings.
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Tel.: 0232-201072; Fax: 0232-201472
ACADEMIC CALENDAR
The Structure of the Academic Year 2009 – 2010 (form of study: full time courses)
1st Semester (Years I and II)
¾ 28 September – Opening of the academic year
¾ 28 September – 20 December – 12 weeks of didactic activity and evaluation
¾ 21 December – 10 January – Winter holiday
¾ 11 January – 7 February – 4 weeks of didactic activity and evaluation
¾ 8 February – 21 February – 2 weeks holiday
¾ In the period 8 February – 21 February it can be held a session, about one week, for
the exams not passed, re-examinations for supplementing the score, re-examinations for
getting higher grades. During February 15 – 21st it will be held a session for exams that have
not been passed at the master's degree examination because of the fact that the students
were absent from the exam or did not pass the exam in the previous academic year.
2nd Semester (year I)
¾ 22 February – 20 June – 16 weeks of didactic activity and evaluation. One week
holiday during the Easter Days.
¾ 21 June – 4 July – 2 weeks practical training. The school situation for the current
academic year ends on July 4th.
¾ 4 Juny – 1 October – summer holiday. During this period, it can be held a session,
about one week, for the exams not passed, re-examinations for supplementing the score, reexaminations for getting higher grades.
2nd Semester (year II, final)
¾ 22 February – 20 June – 16 weeks of didactic activity and evaluation. One week
holiday during the Easter Days.
¾ 21 June – 4 July – 2 weeks for finishing the diploma paper and the registration for
the final examination.
¾ 5 July – 11 July – sitting for the final examination.
UNIVERSITY “AL. I. CUZA” IASI
FACULTY OF BIOLOGY
R E F E R A T E,
The students from the Master Degree Studies and Doctorate School in the Faculty of
Biology have the Reader Professor Carmen Gache, Ph. D. like consulting teacher1.
DEAN,
PRO-DEAN,
Professor PhD Ioan Moglan
1
Reader Professor PhD Luminita Bejenaru
Aprobat in Sedinta Consiliului Facultatii de Biologie din 17.11.2009.
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II. THE ACADEMIC OFFER IN THE MASTER DEGREE
SCHOOL (FACULTY OF BIOLOGY), 2009 – 2011
SPECIALIZATIONS – GENERAL PRESENTATION & CURRICULA
BIODIVERSITY AND PRODUCTIVITY OF THE ECOSYSTEMS
SHEETS OF DISCIPLINES FROM THE CURRICULUM
MOLECULAR GENETICS
MICROBIAL AND CELLS BIOTECHNOLOGIES
BIO-PROCEEDINGS IN AGRO-ALIMENTARY INDUSTRIES
ENVIRONMENTAL CONSULTANCY
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SPECIALIZATIONS – GENERAL PRESENTATION &
CURRICULA
The programs of study represent the planning of all didactic activities throughout the
four semesters of study (university master degree studies ending with master degree’s
examination) for all sections of the two fields within our faculty. Going through the entire
academic development during the two years of study, according to the disciplines chosen
from the curriculum, based on the individual choice leads to a total of 120 credits that one
student needs to gather. If the student wants, he can attend the pedagogic training module,
which comprises a number of disciplines which cumulate 30 credits.
The master’s degree graduates may choice to attend a third cycle of studies (doctor’s
degree – 3 years), after the graduation from a two-year doctor’s degree school. The title of
Doctor in Biology diversifies the opportunities of fulfilling an academic career, allowing the
access to the university educational system and to scientific research.
UNIVERSITY DEGREE DOMAIN AND SPECIALISATIONS
BIOLOGY
¾ BIODIVERSITY AND PRODUCTIVITY OF THE ECOSYSTEMS
During the last decades, the people understood that the nature has it laws and one
uncontrolled evolution despite or even it vulnerability under different forms of human
pressures. The progressive or rapidly environmental degradation brought numerous plant
and animal species close to the extinction risk, the most affected being the stenotope
species for restrictive biomes or habitats.
The European Union initiated the Natura 2000 Programme in order to create a
network of protected areas, starting from the Bird’s Directive and Habitats’ Directive. The
most important of these surfaces will receive a national park status or international
importance natural reserves (Ramsar sites, reserves of biosphere) with specific
administrative structures that will implement permanent sustainable exploitation,
management and biodiversity’ conservation programmes.
During the last years, Romania had harmonised the national environmental legislation
with the EU laws and principles, but it is absolutely urgent the forming and training of high
specialists in long-term environmental politics and strategies’ development in order to
preserve the biodiversity and for the sustainable exploitation of the natural resources, but
also to implement these in the daily practices.
Our faculty offer this master degree studies program beginning from the middle ’90,
following to form specialists with scientific administrative and legislative competencies to
manage the problems involved in the sustainable management of biodiversity and
sustainable exploitation of the natural resources. The principal aim of curricula is to increase
the practical applicability of the theoretical knowledge developing the skills to initiate and
implement the programmes for the sustainable management of the natural resources.
The dissertation paper’s topic represents one study on the diversity of one group f
organisms from one ecosystem, presenting, also, a project of measures that can assure the
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harmonisation of local community’s economic interests with the nature’s preserve in that
ecosystem.
Through their participation in different research programmes on biodiversity topics
ongoing in our faculty scientific teams, but in some practical training, too, the students of this
master degree studies programme can:
- accumulate a good knowledge of the ecosystems’ complexity and inter-relations
between organisms;
- obtain a complete image on the economic, scientific and aesthetic potential of the
natural ecosystems in conditions of correctly management and exploitation;
- understand and analysing the problems of the biodiversity’s conservation;
- know the methodology to resolve different environmental crisis situations;
- elaborate and implement important environmental projects regarding the
amelioration of the environmental quality and, consequently, of the human life’s quality, too.
Perspectives after graduation:
specialists in Environmental Protection Agencies;
specialists in Forestry Administration Directions;
specialists in Authorities for Waters’ Exploitation;
specialists in different Governmental Institutions;
specialists in institutions and agencies involved in the impact studies’ elaboration;
specialists in the staff of Administrative structures in national parks and biosphere’s
reserves;
specialists in non-governmental organisations;
specialists in Research Institutions and research laboratories from Universities;
didactic and research activity in universities.
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"Al. I. Cuza" Iasi University
Faculty of Biology
APROVED
Valid for :
1st Year: 2009 - 2010
2nd Year: 2010 - 2011
PROGRAMMES OF STUDY
University degree domain: Biology
Specialisation: Master Degree – Biodiversity and productivity of the ecosystems
Length of studies: 2 years (4 semesters)
Academic form: full time courses
No.
Name of the subject
No. of classes per week
C
S
L
Credits
Pr
Evaluation type
Colloquium
Exam
1ST SEMESTER (1ST YEAR)
1
Biodiversity of Aquatic Environment
2
1
0
6
I
2
Biodiversity of Terrestrial Environment
2
1
0
6
I
3
Legislation concerning Biodiversity
1
1
0
6
I
4
Forrest and Hunting Resources
1
2
0
6
I
5
Aquatic Resources
1
0
2
6
I
7
5
2
30
TOTAL
nd
2
ST
SEMESTER (1
0
5
YEAR)
1
Biodiversity Conservation
1
2
0
6
II
2
Ecology of Super-individual Biologic Systems
1
1
0
6
II
3
Biostatistics Principles in Quantitative Ecology
1
2
0
6
II
4
Genofond Dynamic in Natural and Anthropic Ecosystems
2
0
0
6
II
5
Vegetal and Animal Morphogenesis
2
2
6
II
TOTAL
7
5
2
30
0
5
3rd SEMESTER (2nd YEAR)
1
Principles of Mollecular Taxonomy
2
0
0
6
III
2
Practical Methods for Monitoring and Evaluation of Some Plant and Animal
Groups
2
0
4
10
III
3
Major Phases of Evolution
2
1
0
7
III
4
Conservation Strategies in the Protected Areas
2
2
0
7
III
8
3
4
30
TOTAL
th
nd
4 SEMESTER (2
0
4
YEAR)
1
Deterioration and Reconstruction of Ecosystems
2
2
0
6
IV
2
Evaluation Principles of Ecosystem Productivity
2
0
2
6
IV
3
Evaluation of Anthropic Impact and Environment Balance
1
1
0
6
IV
4
Management of Environmental Projects
2
2
0
6
IV
5
Magnum practicum
0
0
6
6
IV
6
Research Training and Documentation for Final Paper (4 weeks)
(facultative)
0
0
90
5*
IV
7
5
8
30
TOTAL
No.
1
2
0
5
Pedagogical training II (facultative): 30 credits – according the Annexe 4 of O.M. 4316 from 03.06.2008 valid only for the graduates of
promotion 2005-2008 (3 years)
No. of classes
Examination
Name of the discipline
Sem.
Credits
type
C
A
Psycho-pedagogy of teen-agers, young and adults
Projection and management of educative programmes
1
2
17
28
28
14
14
5
5
Exam
Exam
3
Didactics of Specialty (high school, post-high school and university levels)
3
28
14
5
Exam
4
Teaching Training (high school, post-high school and university levels)
4
0
42
5
Colloquium
2
14
28
5
Exam
3
14
28
5
Exam
30
5E+1C
5
Exam
5
6
Optional courses 1 (to choice one course):
a. Educative communication
b. Consulting and professional orientation
c. Educative research methodology
d. Integrated education
a. Education’ sociology
b. Management of educative institutions
c. Educative politics
d. Multicultural education
e. Modern pedagogical doctrines
Number of classes per week / Total number of credits
Graduate exam, Level II
1
2
3
4
4
IMPORTANT NOTES:
The structure of the academic year is established by the Senate’s Decision of the "Al. I. Cuza" University from Iasi.
The credits allocated for the discipline "Practice in research, documentation and elaboration of the final thesis" are not to be taken into account for the
average of the 4th semester.
The students from the promotion 2005 – 2008 (3 years) must attend and promote the pedagogical training’s courses in order to work like teachers in
the high-schools, post-high schools and universities.
The modality of defense of the final master degree paper is established by the Senate’s Decision of the "Al. I. Cuza" University from Iasi.
The master’s degree in Biology, specialization BIODIVERSITY AND PRODUCTIVITY OF ECOSYSTEMS can be conferred only to students that have
obtained 120 credits in the obligatory disciplines from the hereof syllabus.
18
Course’s name: Biodiversity of Aquatic Environment
CREDITS ECTS: 6
Semester I
Course’s holder: Professor PhD Mircea NICOARA & Lecturer PhD Mihai COSTICA
Objectives: Knowledge of the particularities of the hydrobiocoenoses from the inner and marine
waters; description of the hydrobionts’ adaptations to the aquatic environment, according to the
organoleptic, physical, chemical characteristics and water dynamics; formation of the ecological
conception regarding the sustainable exploitation of the aquatic resources.
Recommended/obligatory courses: Botany, Zoology, Ecology, Hydrobiology.
General topic:
The concept of biodiversity: definition, importance, threats
Communities of aquatic organisms (ecological groups)
Biodiversity of the underground aquatic environments
Biodiversity of the lotic aquatic environments (running waters)
Biodiversity of the lentic aquatic environments (still waters)
Anthropogenic (artificial) aquatic systems
Biodiversity of the marine and oceanic aquatic environments
Management of the aquatic ecosystems biodiversity
Legislation regarding the conservation of aquatic environments biodiversity
Seminar’s topic:
Wetlands’ plant biodiversity
Aquatic environments’ plant biodiversity
Invertebrates specific to the aquatic ecosystems
Vertebrates specific to the aquatic ecosystems
References
Boisteanu T., 1980 - Hidrobiologie (curs), Ed. Univ. "Al.I. Cuza", Iasi
Curry-Lindhal, K., 1970 - Importanta internationala a zonelor umede din Europa meridionala si mai
ales a Deltei Dunarii, Ocr. Nat., 14, 1: 5-20
Magurran A.E., 2004 – Measuring Biological Diversity, Blackwell Publishing, Oxford
Mustata Gh., 1998 – Hidrobiologie (curs), Ed. Univ. "Al.I. Cuza", Iasi
Nicoara M., 2000 – Hidrobiologie (curs), Ed. Univ. "Al.I. Cuza" Iasi
Nicoara M., 2002 – Ecologie acvatica, Casa de Editura Venus, Iasi
Nicoara M., 2008 - Biodiversitatea mediilor acvatice, PIM, Iasi
Nicoara M., Ureche D., 2008, (Editia a II-a, completata si revizuita) - Ecologie acvatica, PIM, Iasi
Pop E., 1960 - Mlastinile de turba din R.S.R., Ed. Acad., Bucuresti
Pora E.A., Oros L, 1974 - Limnologie si oceanologie, Ed. Did. si Ped., Bucuresti
Teaching methods: Lectures, case study, euristic conversation, video projection
Evaluation: Learning the theoretic knowledge and presenting practical skills typical for the
course. Partial and final evaluation (written and oral presentation).
Teaching language: Romanian
Course’s name: Biodiversity of terrestrial environments
CREDITS ECTS: 6
Semester I
Course’s holder: Reader Professor PhD Carmen GACHE & Lecturer PhD Mihai COSTICA
Objectives: Knowledge on the biodiversity’s concept.
Knowledge of the influencing factors on the biodiversity
Deep understanding of the specific, floristic and faunistic diversity concepts
Forming one ecological concept of the relation humanity - biodiversity
Knowledge of the biodiversity conservation’s levels.
Recommended/obligatory courses: Botany, Zoology, Ecology.
General topic:
Knowledge on the biodiversity’s concept.
Knowledge of the influencing factors on the biodiversity
Deep understanding of the specific, floristic and faunistic diversity concepts
Forming one ecological concept of the relation humanity - biodiversity
Knowledge of the biodiversity conservation’s levels
Seminar’s topic:
Fieldwork application – Biodiversity of some terrestrial ecosystems from the north/eastern
region of Romania.
Nature 2000 Network – European concept for the biodiversity conservation
Implementation of the Nature 2000 Network in Romania
Model to elaborate a management plan for one Nature 2000 sit
References
Botnariuc, N., 1999 – Evolutia sistemelor biologice supraindividuale, Ed. Universitatii din
Bucuresti, Bucuresti
Ciocarlan V., 2000 - Flora ilustrata a Romaniei, Pteridophyta et Spermatophyta, Ed. Ceres,
Bucuresti
Cristea V., 1993 – Fitocenologia si vegetatia Romaniei, Ed. Univ. Cluj-Napoca
Cristea V., Gafta D., Pedrotti Fr., 2004 – Fitosociologie, Ed. Univ. Cluj-Napoca
Parvu, C., 2001 – Ecologie generala, editia a II-a, Ed. Tehnica, Bucuresti
Primack, R. B., Patroescu, Maria, Rozylowicz, R., Ioja, C., 2002 – Conservarea diversitatii
biologice, Ed. Tehnica, Bucuresti
Ramade, F, 1991 – Eléments d’ écologie. Ecologie appliqué – action de l’ homme sur la
biosphère, editia a IV-a, Ed. McGraw – Hill, Paris
Sarbu I., Stefan N., Ivanescu Lacramioara, Manzu Ciprian, 2001 - Flora ilustrata a plantelor
vasculare din estul Romaniei, Determinator, vol. I, II, Ed. Univ. Iasi
Stugren, B., 1992 – Ecologie teoretica, Ed. Sarmis, Cluj Napoca
Stefan N., 2005 – Fitocenologia si vegetatia Romaniei, Ed. Univ.”Al. I. Cuza” Iasi
Vadineanu, A. (editor) si colab., 2004 – Managementul dezvoltarii: o abordarea sistemica, Ed.
Ars Docendi, Bucuresti
Zanoschi V., Sarbu I., Toniuc Angela, 1996 - Flora lemnoasa spontana si cultivata din Romania,
Vol I, in Ed. Glasul Bucovinei, Iasi si Vol II, in Ed.Univ. “Al.I.Cuza” Iasi
Teaching methods: Lectures, debates, case study, modelling - brainstorming
Course’s name: Legislation concerning biodiversity
CREDITS ECTS: 6
Semester I
Course’s holder: Professor PhD Mircea NICOARA
Objectives: Knowledge of the national, European, and international legislation and of strategies
for capitalization and conservation of bio-resources; presentation of the impact of the hunting,
fishing and excessive sampling upon the biodiversity of certain ecosystems; formation of the
ecological conception regarding the sustainable use of environmental resources.
Recommended/obligatory courses: Botany, Zoology, Hydrobiology.
General topic:
The Biosphere as a resource
The terrestrial and aquatic biodiversity
Biodiversity role in the stability and regulation of ecological systems
The international law of biodiversity
Directives of the European Union
Conventions ratified by the Romanian state
Policies for the protection of the biological diversity
The protected areas
The network Nature 2000
The global network of biosphere reserves
Seminar’s topic:
International conventions regarding the conservation and exploitation of the forest and game
resources
The Romanian legislation regarding the protection of the environment and game –
interpretation, positive/negative aspects related to biodiversity and game species conservation
Lobby techniques for modification of the environmental legislation
References
20
Bobica N., 1994 – Elemente de ecologie si dreptul mediului inconjurator, Edit. Fundatiei
Chemarea, Iasi
Dutu M., 1995 – Dreptul international si comunitar al mediului, Edit. Econ., Bucuresti
Dutu M., 1998 - Dreptul mediului. Tratat. Vol I si II, Edit. Econ., Bucuresti
Hey C., 1995 - Legislatia de mediu a Uniunii Europene, Friends of the Earth Europe,
Rhododendron, Tg. Mures
Nicoara M., 2003 - Legislatia mediului, Ed. Univ. "Al.I. Cuza" Iasi
Nicoara M., 2009 – Legislatie, institutii si politici de mediu, Editura Tehnopress, Iasi
Nicoara M., 2009 – Monitoring ecologic, Editura Tehnopress, Iasi
Nicoara M., Bomher E., 2004 - Ghidul ariilor protejate din judetul Iasi, S.C. Tipografia Moldova,
Iasi
*** 2002 - Dezvoltarea prevederilor pentru conservarea naturii in Romania, Institutul European din
Romania, Bucuresti, 190 p.
*** H.G. nr. 230/2003, privind delimitarea rezervatiilor biosferei, parcurilor nationale si parcurilor
naturale si constituirea administratiilor acestora
*** Ordonanta de urgenta a Guvernului, nr. 236/2000, privind regimul ariilor naturale protejate,
conservarea habitatelor naturale, a florei si faunei salbatice, aprobata cu modificari si completari
prin Legea nr. 462/2001
Teaching methods: Lectures, debates, case study, brainstorming
Course’s name: Forrest and Hunting Resources
CREDITS ECTS: 6
Semester I
Course’s holder: Lecturer PhD Ciprian MANZU & Lecturer PhD Constantin ION
Objectives: To assimilate issues about of the Romanian characteristics of the forest resources,
their importance and the actual politics of management.
Comprehensive the cognizance concerning to: the biology of game hunting animals; the
importance of game hunting animals for nature economy and for human being.
Recommended/obligatory courses: Phanerogams Systematic, Plant Taxonomy; General
Ecology, Phytosociology and Romania's Vegetation; Animal Biology, Animal Taxonomy,
Ethology
General topic:
The Romanian forest resources. The zonality and floor vegetation of Romania. Main types of
forest habitats. Actual politics regarding forest resources of Romania
The hunting patrimony.
The biology of game hunting animals. The classification of game hunting animals. The
distribution of game hunting animals. The senses of game hunting animals
The bonity of hunting areas. The game hunting mammals. The game hunting birds. The game
hunting animals’ protection and care. The game hunting animals protection. The pest control of
game hunting animals. The ensuring food for game hunting animals. The colonization of game
hunting animals
The game hunting animals diseases
Seminar’s topic:
Main forest ecosystems types. Structural particularities of the forest ecosystem. Structure of the
forest biocenosis; Ecological factors from the forest ecosystem. Human influence on the forest
dynamics
The methods for monitoring game hunting animals. The identification of game hunting animals
traces in field trip. The utilization of telemetry and radiolocation apparatuses for estimation
distribution of game hunting animals. The estimation of effectives on bands transects or
observation from fix point. Methods of estimation for bonity of hunting areas
References
Bodea M., Comsia A. M., Cotta V., Feneser Ghe., Filipascu A., Pop I., Rosseti-Balanescu C.,
Rudescu L., Saulescu N., Stravoiu N. A., Volosciuc A., 1964, Vanat si vanatoare, Edit. Asoc.
Generala a Vanatorilor si Pescarilor Sportivi din R.P.R. , Bucuresti
Chifu T., Manzu C., Zamfirescu Oana, 2006. Flora si vegetatia Moldovei (Romania), II, Edit.
Univ. „Al. I. Cuza” Iasi: 11 – 21
21
Chirita C. (red.), 1981. Padurile Romaniei - Studiu monografic, Edit. Acad., Bucuresti: 573 p.
Ciuta G., 1961. Produsele accesorii ale padurii si valorificarea lor, Edit. Agrosilvica, Bucuresti:
242 p.
Colibaba E., Damina G., 1977, Cartea vanatorului, Edit. Junimea, Iasi
Cotta V., Bodea M., Micu I., 2001, Vanatul si vanatoarea in Romania, Edit. Ceres, Bucuresti
Cristea V., Gafta D., Pedrotti Fr., 2004. Fitosociologie, Edit. Presa Universitara Clujeana, ClujNapoca: 394 p.
Donita N., Chirita C., Stanescu V., 1990. Tipuri de ecosisteme forestiere din Romania, Red.
Prop. Tehn. Agr., Bucuresti
Giurgiu V. (red.), 1997. Silvologie, I, Edit. Acad. Rom., Bucuresti: 28 – 110, 143 – 161
Giurgiu V. (red.), 1999. Silvologie, II, Edit. Acad. Rom., Bucuresti: 65 – 105, 266 - 271
Maanen, E. van, G. Predoiu, R. Klaver, M. Soulé, M. Popa, O. Ionescu, R. Jurj, S. Negus, G.
Ionescu, W. Altenburg 2006. Safeguarding the Romanian Carpathian Ecological Network. A
vision for large carnivores and biodiversity in Eastern Europe. A&W ecological consultants,
Veenwouden, The Netherlands. Icas Wildlife Unit, Brasov, Romania
Pascovschi S, Sburlan D., 1966 Padurile Romaniei, Edit. Agrosilv., Bucuresti
Sarbu I., Stefan N., 1997. Resurse forestiere, Edit. Univ. “Al. I. Cuza” Iasi
Teaching methods: Lectures, euristic conversation, Video-projection, demonstration, explication,
observation.
Course’s name: Aquatic resources
CREDITS ECTS: 6
Semester I
Course’s holder: Reader Professor PhD Victor Surugiu & Lecturer PhD Mihai COSTICA
Objectives: Biological substantiation of the exploitation of the living resources
Appropriation of the renewable and non-renewable resources concept
Understanding the general principles of aquaculture
Knowledge of the factors influencing primary and secondary production
Familiarisation with the strategies for sustainable management of aquatic resources
Recommended/obligatory courses: Hydrobiology, General ecology.
General topic:
Hydrosphere as a resource
Food resources - The present state of world fisheries and aquaculture; The main exploited
species
Fishing methods - Active methods of capture; Passive methods of capture
The human impact on fisheries - The Maximum Sustainable Yield Concept; The causes of the
reduction of stocks; The overexploitation of whales
Aquaculture - General principles of aquaculture; Biotechnology of raising of main species;
Problems and restrictions in the development of aquaculture
Biological productivity of aquatic ecosystems - Primary production and productivity; Secondary
production and productivity
Economical and legal aspects of the aquatic resources exploitation.
Seminar’s topic:
Spectro-photometric determination of the chlorophyll a concentration.
Determination of the photosynthetic rate of the phytoplankton by „light and dark bottles method”
Determination of biometric parameters and the calculation of some biometric indices and
coefficients
Age determination of fishes by scale markings and indirect assessment of stocks of a fish
population by capture-marking-recapture method (Petersen method)
Calculation of the growth-rate, the survival rate and the degree of the food valorisation by fishes
Length-weight correlation
Construction of the size-frequency histograms and the modal analysis by the Bhattacharya
method
Assessment of the secondary production (P) of a population with identifiable cohorts by the
Crisp method and the calculation of the turnover (P/B)
Indirect determination of the fish productivity
References
22
Battes, K., Mazareanu, C., Pricope, F., Caraus, I., Marinescu, V., Rujinschi, R., 2003. Productia
si productivitatea ecosistemelor acvatice. Ed. “Ion Borcea”, Bacau, 339 pp.
Downing, J.A., Rigler, F.H. (sub red.), 1984. A Manual on Methods for the Assessment of
Secondary Productivity in fresh Waters, IPB Handbook, 17, Ed. a 2-a, Blackwell Scientific
Publications, Oxford-London-Edinburgh-Boston-Melbourne, 501 pp.
Gheracopol, O., Bogatu, D., Munteanu, G., 1977. Valorificarea unor indicatori fizico-chimici si
biologici pentru aprecierea capacitatii biogenice a helesteielor ciprinicole. Tehnica piscicola,
Univ. Galati, 5: 51-58.
Pricope, F., Battes, K., Petrovici, M., 2007. Hidrobiologie. Lucrari practice. Ed. Alma Mater,
Bacau, 143 pp.
Surugiu, V., 2008. Limnobiologie si saprobiologie. Compendiu de lucrari practice. Ed.
Tehnopress, Iasi, 331 pp.
Vollenweider, 1984. A Manual on Methods for Measuring Primary Production in Aquatic
Environments. IPB Handbook, 12, Ed. A 3-a, Blackwell Scientific Publications, Oxford-LondonEdinburgh-Boston-Melbourne.
FiSAT II software (http://www.fao.org/fi/oldsite/STATIST/fisoft/fisat/index.htm)
Teaching methods: Lectures, case study, brainstorming
Course’s name: Biodiversity Conservation
CREDITS ECTS: 6
Semester II
Course’s holder: Professor PhD Catalin TANASE
Objectives: To define biodiversity concept, genetic diversity, biological communities diversity,
ecosystem diversity, ecological reconstruction;
To define general problems of diversity;
To describe the biodiversity conservation in Romania;
To explain species extinction phenomenon;
To explain the importance of ex-situ and in-situ biodiversity conservation strategies;
To characterize the institutions acting in the domain of animals and plants ex-situ conservation.
Recommended/obligatory courses: Aquatic environment biodiversity; Terrestrial environment
biodiversity; Legislation regarding biodiversity conservation; Forestall and cinegetical recourses;
Aquatic recourses
General topic:
Introduction in the interdisciplinary domain Biodiversity Conservation
Definitions and general considerations
Categories of biodiversity
Natural capital
Biodiversity conservation strategies
Seminar’s topic:
Distribution model of the terrestrial species.
Species extinction concept. Extinction rate. Types of species extinction. Extinction models.
Natural and anthropic causes of species extinction.
Population monitoring. Demographic studies. Analysis of population variability. Species and
ecosystems monitoring on long term.
Concept of ex-situ conservation.
Categories IUNC (International Union of Nature Conservation) of species conservation.
In-situ preservation of natural communities and of populations in wildness.
Concept of ecologic reconstruction. Priority areas for ecological reconstruction.
National and international approaches of biodiversity conservation and sustainable
development. Action plan in Romanian biodiversity conservation domain.
References
Cristea V., Denaeyer Simone, 2004, De la Biodiversitate la OGM-uri ? Ed. Eikon, Cluj-Napoca
Dragulescu C., Curtean-Banaduc Angela, 2002, Conservarea biodiversitatii. Entitati naturale
protejate, Ed. Mira Design, Sibiu
Primack R.B., Patroescu M., Rozylowicz L., Joja C., 2002, Conservarea diversitatii biologice,
Ed. Tehnica, Bucuresti
23
Scott J. M., 1993, Gap Analyses: a geographic approach to protection of biological diversty,
Wildlife Monographs
Vadineanu A., 1998, Dezvoltarea durabilitatii. Teorie si practica, Ed. Universitatii din Bucuresti
Teaching methods: Lectures and video-projections; field applications in national and natural
parks, in natural reserves.
Course’s name: Ecology of Supraindividual Biologic Systems
CREDITS ECTS: 6
Semester II
Course’s holder: Reader Professor PhD Stefan ZAMFIRESCU & Lecturer PhD Mihai COSTICA
Objectives: Comprehension of some notions concerning the general characteristics of
ecological systems.
Understanding of the conditions that led to organisational hierarchy evolution.
Knowledge of the degree in which population characteristics contributes to the organisational
evolution of populations and communities.
Recommended/obligatory courses: General Ecology.
General topic:
Biological systems: generalities, characteristics, hierarchies.
Organisational evolution of population.
Reproduction and sexuality in animals. Sexual selection. Survival strategy.
Interactions between generations: parental care, parent-progeny conflict, cannibalism.
Population dispersionl Social distance and territory; Population diversity.
Communication. Social behaviour.
Seminar’s topic:
Exemplification of system types. Exemplification of the characteristics of biological systems.
Horizontal and vertical evolution. Characteristics of the categories of the taxonomic and
organisational hierarchies.
Survival strategies - characteristics
Evolutionary tendencies of parental care.
Effects of cannibalism on individual and population levels.
Aspects of population structure and dispersion.
Exemplification of social behaviour in invertebrates and vertebrates.
References
Begon, M., Townsend, C.R., Harper, J.L. (2006): Ecology: From individuals to ecosystems 4th
edition. Blackwell Publishing Ltd.,
Botnariuc, N. (1999): Evolutia sistemelor biologice supraindividuale. Ed. Univ. din Bucuresti,
Bucuresti.
Isac, M., Filipescu, C., Isac, R. M. (1996): Biofizica – de la Big-Bang la ecosisteme. Vol. I., Ed.
Tehnica, Bucuresti.
Stiling, P. D. (1996): Ecology Theories and Applications. ed. a II-a, Prentice Hall, New Jersey.
Varvara, M. (2000): Curs de Ecologie. Vol. 1, Ed. Univ. “Al. I. Cuza” – Iasi.
Varvara, M., Zamfirescu, .R., Neacsu, V. (2001): Lucrari practice de ecologie – manual. Ed.
Univ. “Al. I. Cuza” Iasi.
Vadineanu, A. (1998): Dezvoltarea durabila: teorie si practica. Ed. Univ. din Bucuresti,
Bucuresti.
Wilkinson, D.M. (2006): Fundamental Processes in Ecology: an Earth Systems Approach.
Oxford University Press Inc., New York.
Wilson, E.O. (2003): Sociobiologia. Editura trei, Bucuresti (L. Ulrich & G. Strungaru).
Teaching methods: Lectures, euristic conversation, demonstration, practical applications.
Course’s name: Biostatistics Principles in Quantitative Ecology
CREDITS ECTS: 6
Semester II
Course’s holder: Reader Professor PhD Stefan ZAMFIRESCU
24
Objectives: Comprehension of theoretical knowledge applicable in ecology
Understanding of the role of statistical methods in ecological research.
Knowledge of the principles statistical testing techniques applicable in ecology.
Recommended/obligatory courses: Informatics applied in biology, General Ecology.
General topic:
Definition and utility of statistics.
Data assessment and presentation: Data and variables; Variable types and scales.
Descriptive statistics – measurement of central tendency and variability in samples.
Discrete probabilistic distributions: Binomial and Poisson.
Continuous probabilistic distributions: Normal distribution; Normal standard distribution.
Introduction in inferential statistics. Confidence interval of population mean.
Testing statistical hypotheses and scientific methodology: Testing hypothesis concerning the
mean of a single population (t (Student) test for one sample); statistical decision-making.
Comparison of 2 independent samples: t (Student) test for independent observations; MannWhitney test.
Comparison of 2 related samples: t (Student) test for related observations; Wilcoxon test.
Analysis of variance (ANOVA): principles; models.
ANOVA Two-factor models; Nonparametric ANOVA (Kruskal-Wallis, Friedman).
Correlation and Regression: comparison; Correlation analysis.
Linear regression analysis.
Analysis of frequencies and nominal data: Chi-square test for concordance; Chi-square test for
association; Fisher exact test; McNemar test for significance of change.
Seminar’s topic:
Statistics utility – application. Variable types and scales – exercises.
Frequency distribution and graphical presentation – exercises.
Description of the central tendency and variability of a sample – exercises.
Probabilistic distributions and their role in biostatistics – exercises.
Testing hypothesis concerning the mean of a single population: t (Student) test for one sample
– exercises.
Tests for two independent samples: Student and Mann-Whitney – exercises.
Tests for two related samples: Student and Wilcoxon – exercises.
One-factor ANOVA – exercises.
Two-factor ANOVA – exercises.
Nonparametric ANOVA: Kruskal-Wallis, Friedman – exercises.
Correlation analysis – exercises.
Regression analysis – exercises.
Chi-square tests for concordance and association, Fisher test, McNemar test – exercises.
References
Bailey, T.J.N. (1981): Statistical Methods in Biology. Editia a II-a. Ed. Cambridge University
Press.
Bishop, O.N. (1971): The Principles of Modern Biology - Statistics for Biology. Editia a II-a. Ed.
Longman.
Cocs, W. G. (1996): Laboratory Manual of General Ecology. Editia a VII-a. Ed. Wm. C. Brown
Publishers.
Hampton E.R. (1994): Introductory Biological Statistics. Ed. Wm. C. Brown Publishers
Iosifescu M., Moineagu C., Trebici V.,Ursianu E. (1985): Mica enciclopedie de statistica. Ed.
tiintifica si Enciclopedica, Bucuresti
Snedecor, W.G. (1968): Metode statistice aplicate in cercetarile de agricultura si biologie
(traducere din limba engleza). Bucuresti.
Fowler, J., Cohen, L., Javris, P. (2000): Practical Statistics for Field Biology, 2nd
edition, Ed. John Wiley and Sons, Chichester, New York, Weinheim,
Brisbane, Singapore, Toronto.
Zamfirescu, S.R., Zamfirescu, O. (2008) Elemente de statistica aplicate in Ecologie. Ed. Univ.
„Al.I. Cuza” Iasi.
25
Course’s name: Genofond Dynamic in Natural and Anthropic Ecosystems
CREDITS ECTS: 6
Semester II
Course’s holder: Professor PhD Constantin TOMA, C. M. of the Romanian Academy
Objectives: Learning the fundamental concepts regarding the ontogenetic and phylogenetic
development of superior vegetal organisms and realization of floristic associations for different
geographic regions.
Profound study regarding the succession of vegetation on Glob.
Recommended/obligatory courses: Plant Cytology and Histology, Plant Morphology Anatomy,
Plant Biology, Plant Physiology, Plant Taxonomy, Cryptogams’ Systematic, Phanerogams’
Systemtic.
General topic:
General characteristics and causes of vegetation succession; dynamics of plant communities.
Dynamics of vegetation in easily flooded forests
Dynamics of woody vegetation on sands
Successions in mixed foliage forests
Expansion and retiring of Fagus on hills and plain
Relations between Quercus species and resinous plants
Concurrence between Fagus, Abies and Picea
Role of Pynus sylvestris in dynamics of montain vegetation
Sudden destruction of forests and its effects
History of forest vegetation in Romania
Evolution of vegetations in different regions of Romania and formation of forest steppe
Dynamics of vegetation under the influence of anthropic and phytibiotic factors
Changes in phytocenosis
Succession in herbaceous vegetal associations
Vegetal genetic resources
References
Borza Al., Boscaiu N. - 1965 – Introducere in studiul covorului vegetal. Ed. Acad. Rom.,
Bucuresti.
Bujorean Gh. - 1930 – Contributiuni la cunoasterea succesiunii si intovarasirii plantelor. Bul.
Grad. Bot. Si Muz. Bot. Univ. Cluj, t X, nr. 1-4: 1-94.
Cristea M. - 1981 - Resurse genetice vegetale. Ed. Acad. Rom. Bucuresti.
Pascovschi S. – 1967 – Succesiunea speciilor forestiere. Ed. Agro-Silvica Bucuresti.
Puscaru–Soroceanu E., Popova-Cucu A. – 1966 – GeoBotanya. Ed. Stiintifica Bucuresti.
Resmerita I. – 1970 – Flora, vegetatia si potentialul productiv pe masivul Vladeasa. Ed. Acad.
Rom., Bucuresti.
Stefan N. – 2005 – Fitocenologie si vegetatia Romaniei. Ed. Univ. „Al. I. Cuza” Iasi.
Teaching methods: Lectures, different projections, demonstration, brainstorming.
Course’s name: Vegetal and Animal Morphogenesis
CREDITS ECTS: 6
Semester I
Course’s holder: Reader Professor PhD Irina GOSTIN & Reader Professor PhD Luminita
BEJENARU
Objectives: Knowing the phenomena of polarity and symmetry
General knowledge of principles and factors of morphogenesis and cell differentiation,
knowledge of correlations between organs and factors involved;
Presentation of cases of abnormal growth and morphogenesis;
Highlighting the morpho-anatomical changes induced by parasites, pesticides and pollutants;
Discuss the fundamental processes of ontogenesis.
Describe and compare the events that occur during ontogenetic development in animals used
as research models.
Understand the main mechanisms of form self organisation in animals.
Recommended/obligatory courses: Comparative Anatomy, Vegetal and Animal Cytology,
Vegetal and Animal Histology & Embryology.
General topic:
26
General principles and factors of morphogenesis and cell differentiation: cell totipotency, genetic
factors.
Abnormal growth and morphogenesis: abnormal development of organs, producing new types
of organized structures (Galls, amorphous structures: cancers).
Morpho-anatomical changes induced by parasites, pesticides and pollutants
Cell morphogenesis: cell wall morphogenesis (cellulose microfibrils assembly)
Definition – genesis of form in ontogenesis, mechanisms involved in self organisation from
unicellular zygote to complex body, under the influence of genetic and environmental medium.
Fundamental processes in ontogenesis: proliferation, grown, differentiation, cellular death
(apoptosis), integration.
Molecular and cellular basis: adhesion, extracellular matrix. Histogenesis and embryogenesis.
Biology of ontogenetic development in organism used as models for the research of the
morphogenetic processes: Caenorhabditis elegans, Drosophila melanogaster, Dario rerio,
Xenopus laevis, Mus musculus.
Seminar’s topic:
Polarity: external events and internal factors that induce one. Symmetry: symmetry-polarity
correlation, the most common types in different organs.
Substances of cell growth and differentiation, in conjunction with polarity.
Rhysogenesis, caulogenesis, phylogenesis, flower, seed and fruit morphogenesis; mechanisms,
factors, substances involved (stimulatory and inhibitory).
The role of microtubules and the cytoskeleton in this process, in determining the division plan in
stomata motion.
Culture of chick (Gallus domesticus) embryos; Studying early chick (Gallus domesticus)
embryos; Studying chick (Gallus domesticus) embryos after 3 days of culture (hatching);
Studying chick (Gallus domesticus) embryos after 7 days of culture (hatching), including the
extraembryonic membranes.
Confocal laser microscopy of embryo morphology.
References
Adascalitei E., 1980, Curs de embriologie animala, Universitatea « Al.I.Cuza », Iasi.
Andronescu A., 1987, Anatomia dezvoltarii omului, Embriologie medicala, Editura Medicala,
Bucuresti.
Beck F., Moffat D.B., Lloyd, 1973, Human Embriology and genetics, Blackwell Scientific
Publications.
Chiriac R., Indrei A., 1997, Embriologie (Sinteze didactice), Ed. Fundatiei Chemarea Iasi.
Chriqui D., 1995 - Bases cellulaires et Moléculaires de la morphogenese chez les végétaux
superieurs. Univ. Curie, Paris
Comanescu G., Leonov S., Neagu A., 2001, Elemente de citologie, histologie si embriologie
animala, Ed. Media, Bacau.
Crabbe J., 1987 - Aspects particuliers de la morphogenese caulinaire des végétaux ligneux et
introduction fleur étude quantitative. I.R.S.I.A., Bruxelles
Kenneth V. Kardond, 1998, Vertebrates Comparative Anatomy, Function, Evolution,
WCB/McGraw-Hill.
Kumz Y. W., 2004, Developmental Biology of Teleost Fishes, Springer, The Netherlands.
Matova N., Cooley L., 2001, Comparative Aspects of Animal Oogenesis, Developmental
Biologz, p. 1-30.
Mohr H., 1972 - Lectures on Photomorphogenesis. Springer-Verlag, Berlin, Heidelberg, New York
Roland J.C., Reiss D., 1989 (2) - Morphogenese a un niveau supramoléculaire: l'assemblage
oscillant des parois cellulaires. Bull. Soc. Bot. France, 136 (Actual. bot): 245-257
Tuan R. S., Lo C. W. (eds.), 2000, Developmental Biology Protocols, I-II, Humana Press, New
Jersey.
Yoder B. K. (ed.), 2008, Ciliary Function in mammalian Development, Elsevier, Oxford UK.
Teaching methods: Lectures, debates, case study, modelling - brainstorming, experiment,
demonstration
Course’s name: Principles of Mollecular Taxonomy
CREDITS ECTS: 6
Semester III
27
Course’s holder: Lecturer PhD student Eugen UNGUREANU
Objectives: To know and to use fundamental concepts and language concerning molecular
taxonomy.
Recommended/obligatory courses: General Chemistry, General Biochemistry, Enzymology, Cell
Biology, Genetics, Structural organizations of Proteins and Nucleic Acids, Metabolic
Transformations of Aminoacids, Proteins and Nucleic Acids
General topic:
Fundamentals of structure and metabolism of nucleic acids and proteins. Proteins as genome
expression. Molecular taxonomy as a new discipline. Fundamentals about collecting probes and
molecular techniques involved in molecular taxonomy analysis. Phylogenetic trees. Molecular
clock. Evolution and genetic polymorphism. Computers and molecular taxonomy.
References
Artenie Vlad - Biochimie, Editura Universitatii „Al.I.Cuza” Iasi, 1991;
Dumitru I.F. - Biochimie, EDP, Bucuresti, 1980;
Daniel C. Liebler, John R Yates III – Introduction to proteomics – Tools for the new Biology,
Humana Press Inc, 2002;
Daniel Chasman - Protein Structure Determination, Analysis, and Applications for Drug
Discovery, Routledge, 2003;
Buxbaum, E. – Fundamentals of protein structure and function, Springer Verlag, 2007;
C. A. Glasbey, G. W. Horgan – Image Analysis for the Biological Sciences, John Wiley & Sons,
1995; Nei, Masatoshi, Kumar, Sudhir – Molecular Evolution and Phylogenetics, Oxford
University Press, 2000;
nd
Hillis, David, Moritz, Craig, Mable, Barbara – Molecular Systematics, 2 Ed., Sinauer
Associates Publishers, 1996
Teaching methods: Lectures, euristic conversation, debates, brainstorming, case study
Course’s name: Practical Methods for Monitoring and Evaluation of Some Plant and Animal
Groups
CREDITS ECTS: 10
Semester III
Course’s holder: Professor PhD Ioan MOGLAN, Lecturer PhD Ciprian MANZU & Lecturer PhD
Constantin ION
Objectives: Acquirement of theoretical knowledge and practical skills of monitoring and
evaluation for some plants and animals groups; Quality evaluation of some ecosystems, based
on bio-indicators; Practical applications of the monitoring’s methods, evaluation and recognition
of some plants and animals groups.
Comprehensive the cognizance concerning the practical methods of monitoring and evaluation
of some vertebrates groups.
Recommended/obligatory courses: Cryptogams’ Systematic, Phanerogams’ Systematic,
Ecology; Invertebrates Taxonomy, Vertebrates Taxonomy; Entomology, Ornithology, Ethology.
General topic:
General notions concerning the ecological monitoring
Monitoring of the algal communities from the continental waters; Objectives of algae monitoring
from aquatic ecosystems; Structural parameters for algal communities monitoring. Lichens like
bio-indicators. The rol of bryophytes as bio-indicators of the air pollution. The study of
phytocenosis. Phytocenosis’s sampling. The stages of the phytosociological research. The
characterization of the phytocoenoses (physiognomy, qualitative structure); Notions concerning
the mapping of vegetation.
Monitoring and quality assessment of an ecosystem based on groups of invertebrate animals
Qualitative and quantitative assessment methods of some groups of invertebrate animals;
Sampling depending on the target group of invertebrates;
Groups of invertebrates that serve as key indicators of ecosystem biodiversity
Planning of sampling periods for different groups of invertebrates
Predictions and evaluation of the population trend of different invertebrate groups
Study techniques for biodiversity. Methods of collecting vertebrates. The composition of
distribution maps for vertebrates. Mapping the habitats of vertebrates. The monitoring
vertebrates. Methods of collecting observations. Indexes used in monitoring. Probes quadrates
28
and transects. Mapping results. The method of marking, release and recapturing. The principle
of equal effort unity. The monitoring fishes. The monitoring amphibians. The monitoring reptiles.
The monitoring birds. The monitoring mammals. The utilization of habitats. Radiotelemetry. The
diet’ s analyse. The identification of age and sex. The marking of vertebrates. The study of
ecological status of vertebrates. The estimation of reproduction populations. The estimation of
mortality. The study of population changes. The risk of extinction. The molecular techniques for
evaluating vertebrates. The identification of individuals. The identification of species and
populations. The study methods concerning behaviour of vertebrates.
Seminar’s topic:
Practical methods of monitoring and evaluation of the algal communities; Practical methods for
the study of the forest ecosystems; Practical methods for the study of the grassy vegetation,
aquatic and swamp ecosystems; Evaluation of the vulnerability and of the eco-protective
significance of habitats; Methods for mapping vegetation.
Methods of assessment and monitoring of invertebrate groups; Movement to forest and
meadow ecosystems, collecting of sampling using entomological net (total collection of the
grass vegetation, selective collection watching), collecting using Barber traps, taking samplings
of soil and litter, plant organ and galls, and so on; The preparation of samples and preservation
of biological material taken; Choice of entomological material from the sampling to prepare and
conservation of insects; Identification of entomological material to higher taxon (Orders,
Families, Subfamilies), genera and specie (depending by time available); Achievement of
permanent microscopic preparations with antenna, mouth parts, legs, wings and genitalia;
Achievement of entomological collections; Statistical processing of data, preparation of the
report with results obtained
Techniques for ecological and behavioural studies at vertebrates. Techniques of capturing
vertebrates. Techniques of identification vertebrates. The marking vertebrates. The
photographic techniques for study vertebrates. The utilization of telemetry equipment. The
movement study of vertebrates utilizing satellites techniques . The cartographic technique. The
census techniques. The techniques for identification of age and sex.
References
Capinera John, 2004. Encyclopedia of Entomology (vol. 1-3). Kluwer Academic Publishets,
Netherlands, 2580p
Cristea V., 1993 - Curs de Fitosociologie si Vegetatia Romaniei, Univ. „Babes-Bolyai” ClujNapoca: 5-18; 211-230; 260-302
Cristea V., Gafta D., Pedrotti Fr., 2004 - Fitosociologie, Edit. Presa Universitara Clujeana, ClujNapoca: 394 p.
Daly V. H., Doyen T. J. & Purcell H. A. (III), 1998. Introduction to Insect Biology and diversity.
Second edition. Oxford University Press, USA, 680 p
Ionescu A. M., Matilda Lacatusu, 1971. Entomologie. Edit. Did. si Ped., Bucuresti
Linzey D., 2001, Vertebrate Biology, Mc Graw Hill International, Singapore
Marcu Olimpia, I. Tudor, 1975. Protectia Padurilor. Edit. Did. si Ped., Bucuresti
Martin Paul, Beteson Patrick, 2009, Measuring Behaviour, University Press, Cambridge, U.K.
McGavin George, 2001. Essential Entomology. Oxford University Press, 318 p
Pedrotti Fr. 2004 - Cartografia geoBotanya, Pitagora Editrice, Bologna: 236 p.
Romoser S. W. & Stoffolano G. John jr., 1994. The science of Entomology. Ed. Wm. C. Brown,
USA, (Third edition.) 532 p.
Stugren, B., 1992 – Ecologie teoretica, Ed. Sarmis, Cluj Napoca
Sutherland J. William, 2000, The Conservation Handbook. Research, Management and Policy.
Teaching methods: Lectures, euristic conversation, Video-projection, demonstration, explication,
observation.
Course’s name: Major Phases of Evolution
CREDITS ECTS: 7
Semester II
Course’s holder: Reader Professor PhD Ion COJOCARU
Objectives: Knowing the main living world evolution interpretation criteria;
Knowing the major processes characterizing each big evolution stage;
Enlarging upon certain evolution-related qualitative issues
29
Documenting and drafting evolution-relates synthetic papers.
Recommended/obligatory courses: Paleobiology
General topic:
Major stages of the Biotic Environment evolution
Prebiotic Environment. Solar System and Earth Formation. Planets within the Solar System.
Lithosphere Formation. The Oldest Rocks on Earth. Atmosphere Formation. Hydrosphere
Formation. Archaic Earth Climate
Biotic Environment. Life Appearance Environment. Irreversible Life Effects on the Planet
Conditions; Anoxic Environment Period. Body Metabolism in Anoxic Environment (Anoxygenic
Lithotrophy and Synthesis). Anoxic Environment Evolution; Oxygenic Environment Period.
Oxygenic Photosynthesis Appearance. Proofs of the Oxidizing Nature of Living Environments –
Ferruginous Stratified Formations. Consequences of Environment Oxygenation: Appearance of
Eukaryotes; Developing an Antioxidant Enzymatic Intracellular System; Appearance of Aerobic
Respiration; Molecular Nitrogen Fixation; Ozone Layer Formation; Limestone Sedimentation
Intensification; Appearance of Exoskeletal Formations; Evolution in the Oxygenic Environment.
Evolution in the Marine Environment (seashore, pelagic, bathyal). Evolution in the Continental
Environment (land, air and fresh water).
Appearance of Life
Living Matter – General Characteristics; Basic Conditions – Carbon; Water; Prebiotic Chemical
Evolution. Alien Proof. Experiment Proof; Necessary Conditions for a Chemical Evolution to Life;
Prebiotic Chemical Evolution Stages: Synthesis of the Simplest Organic Carbone-, Nitrogenand Hydrogen-Containing Substances. Synthesis of the Main Macromolecular Polymers.
Formation of Macromolecular Complexes Able to Conduct Substance and Energy Exchanges
with the Environment and Capable of Self-reproduction (Replication System Evolution:
Replication Clays; Nucleic Acids). Appearance of the First Forms of Life; RNA Life; Cellular Life
(Appearance of Cell Membrane, Active Transport); Metabolism of the First Forms of Life;
Conclusions regarding the Appearance of Life;The Most Ancient Traces of Life
Major Organization Evolution Stages
Evolution at Cell Level. Prokaryote Cell; Appearance of the Eukaryote Cell; Appearance of
Sexed Reproduction and its Evolution Advantage; Evolution at Multiple-Cell Level; Appearance
and Development of Multiple-Cell Activity; Multiple-Cell Individuals (Solitary or Colonial; Types
of Colonies); Appearance of the Main Evolution Novelties - in Single-Cell Bodies; in Multiple-Cell
Bodies (Protists, Fungi, Plants and Animals)
Major Biodiversity Evolution Stages
Taxonomic Diversity; Individual and Species. Taxonomic Hierarchy; Appearance of the Big
Systematic Units (fields, kingdoms); Characteristics of the Six Kingdoms: Eubacteria,
Archaebacteria, Protista, Plantae, Fungi, Animalia; Vegetable Kingdom Evolution Stages;
Animal Kingdom Evolution Stages; Biodiversity Evolution during Geological Ages (Specific and
Predominant Forms):- Biodiversity in Precambrian; Biodiversity in Paleozoic; Biodiversity in
Mesozoic; Biodiversity in Neozoic; Ecological Diversity - Biocoenosis, Ecosystem, Biome;
Declining Biodiversity. Mass Extinctions (Definition, Characteristics, Causes). Main Mass
Extinctions (Pcm3, Cm3, O3, D3, P, T3, K2).
Seminar’s topic:
Body Adjustment to Marine Life.
Land Colonization by Plants and Animals (Appearance of Terrestrial Cormophytes,
Invertebrates and Vertebrates).
Appearance of Flying Insects, Reptiles, Birds and Mammals.
Evolution of Types of Locomotive in the Terrestrial Environment.
Respiration, Excretion and Reproduction Adjustment in the Terrestrial Environment.
Life in Extreme Environments (Extreme Temperatures, Pressures, Toxicity, Lack of Light,
Parasites, etc.).
Major Environment Conditions Disorders (Climate Warming, Glaciations).
Man – Special Stage of the Evolution of Life on Earth
Main Types of Sea and Land Ecosystems.
Anthropogenic Impact on Biodiversity (Extinctions Caused by Man, Endangered Species).
References
Cojocaru, I., 2002 – Paleobiologie, vol. I, Editura Univ. „Al. I. Cuza” Iasi
Cojocaru, I., 2003 – Paleobiologie, vol. II, Editura Univ. „Al. I. Cuza” Iasi
Cojocaru, I., 2004 – Paleobiologie, vol. III, Editura Univ. „Al. I. Cuza” Iasi
Cojocaru, I., 2005 – Paleobiologie, vol. IV, Editura Univ. „Al. I. Cuza” Iasi
30
Purves, W., G. Orians, H. Craig Heller, D. Sadava, 1997 – Life - the Science of Biology, Sinauer
Associates Inc.
Teaching methods: Lectures, euristic conversation, debates, brainstorming.
Course’s name: Conservation Strategies in the Protected Areas
CREDITS ECTS: 7
Semester III
Objectives: To determine the anthropogenic causes of species extinction;
To organize the activity of monitoring the populations;
To establish design principles of the protected areas;
To determine the most priority areas for ecological reconstruction;
To determine the main pathways in ecological reconstruction of biological communities and
ecosystems;
To argue the sustainable management of the protected areas;
To elaborate management plans for biodiversity conservation.
Recommended/obligatory courses: Aquatic environment biodiversity; Terrestrial environment
biodiversity; Legislation regarding biodiversity conservation; Sustainable management of
biodiversity.
General topic:
Definitions and general considerations
Categories of protected areas
Organizing and managing plan of protected areas
Conservation and sustainable valorization of habitats and species
Management of protected areas
Evaluation of sustainable conservation efficiency of protected areas.
Seminar’s topic:
Categories of protected areas in Romania
Applying human rights in protected areas domain
Photographing
Inhabitants of marginal areas
Forestry
Tourism
Exploitation of deposits and mining industry
Leased or in property areas.
References
Balteanu D., Dumitrascu M., Ciupitu D., 2003, Romania. Ariile naturale protejate, harta, Ed.
Academiei Romane, Bucuresti
Munteanu D., Mihailescu Simona, Coldea Gh. (coordonator), 2003, Parcuri nationale, naturale
si rezervatii ale biosferei din Romania, Ed. Min. APAM, Bucuresti
Rugina Rodica, Mititiuc M., 2003, Plante ocrotite din Romania, Ed. Universitatii „Alexandru Ioan
Cuza” Iasi
Toniuc N., Purdelea L., Boscaiu N., 1995, Aspecte metodologice ale selectarii si gestiunii ariilor
protejate, Ocrot. nat. med. inconj., Bucuresti, 39, 1-2: 15-23
Teaching methods: Lectures and video-projections; field applications in national and natural
parks, in natural reserves.
Course’s name: Deterioration and Reconstruction of Ecosystems
CREDITS ECTS: 6
Semester IV
Course’s holder: Reader Professor PhD Mariana MUSTATA
Objectives: Evaluation of the anthropogenic impact on natural areas and ecosystems;
evaluation of anthropogenic impact on biological diversity and understanding of human beings
reintegration into nature and rebuilding of destroyed ecosystems.
31
Recommended/obligatory courses: General ecology.
General topic:
Introduction. Relationship between humans and nature.
Biosphere is an entire complex thing.
Our planet under pressure; dilemma of our civilisation.
Equilibrium and difficult equilibrium inside of the ecosystems.
Few signs of ecosystem declines - diminution of phreatic water levels; rivers dry up; fish natural
resources are collapsed; lawns deterioration.
Illegal deforestation threats ecological and economic security.
The high temperatures and their effects
Water crisis and food security
Planet asphalting: machines and harvests compete for the planet.
Forest ecosystems from Romania, after 1981.
Agro-systems deterioration in Romania demonstrates the absence of a right ecological politics.
Let’s learn from the past.
International systems used for life maintain.
Human reinstatement into nature.
Ecosystem reconstruction: basis, methods and theories.
Ecological reconstruction of forests.
Ecological reconstruction of fauna from waters.
Ecological reconstruction of natural lawns.
Seminar’s topic:
Ecological analysis of some natural ecosystems from local areas (forest, lakes, rivers etc.);
Main causes which generating soil erosion from local area and some other known areas.
Ecological analysis of some natural reservations which were been affected by anthropic impact
(„Repedea Rocks” Reserve, „David’s Valley” Reserve from Iasi, etc)
Ecological analysis of a destroyed aquatic ecosystem (Case study „Ciric Lake III”).
Anthropogenic impact on a forest: effects of uncontrolled grubbing
Equilibrium and difficult equilibrium into natural areas (seminar)
International systems used for life maintain (seminar).
Human reinstatement into nature (seminar).
References
Botnariuc N, Vadineanu A, 1982 – Ecologie, Ed. Didactica si Pedagogica Bucuresti
Botnariuc N, 1989 – Genofondul si problema ocrotirii lui. Ed. Stiintifica si Enciclopedica,
Bucuresti
Brown R. Lester. „Probleme globale ale omenirii” – 1984 - 1986, 1983 - 1990, 1991, 1994,
1995., Ed. Tehnica Bucuresti
Brown R. Lester, 2006 – Planul B 2.0. Salvarea unei planete sub presiune si a unei civilizatii in
impas, Ed. Tehnica Bucuresti
Cogalniceanu Al, Cogalniceanu D 1998 - Energie, economie, ecologie, Ed. Tehnica Bucuresti
Mohan Gh, Ardelian A, 1993 – Ecologie si Protectia mediului, Ed. Scaiul Bucuresti
Mustata Maria, Mustata Ghe., 2003 – Probleme de ecologie generala si umana, Ed. Universitatii
„Al.I.Cuza” Iasi
Primack B. Richard, Patroescu Maria, Rozula – Wicz Laurentiu, Ioja Cristian, 2002 –
Conservarea diversitatii biologice, Ed. Tehnica Bucuresti
Rojanschi Vl., Bran Fl., 2002 – Politici si strategii de mediu, Ed. Economica, Bucuresti
Taylor Paul, 1986 – Respect for Nature, Princeton, New Jersey, Princeton University Press.
Teaching methods: Lectures, euristic conversation.
Course’s name: Evaluation Principles of Ecosystem Productivity
CREDITS ECTS: 6
Semester IV
Course’s holder: Lecturer PhD Oana ZAMFIRESCU
Objectives: Comprehension of the phytocoenosis structure and function, of the production
function of different types of phytoceonoses and of the factors that influence this function.
Recommended/obligatory courses: Cryptogams systematic, Phanerogams systematic,
Vertebrates Taxonomy, General Ecology
32
General topic:
Ecosystem structure
Ecosystem functions
Fundamentals of ecosystem productivity
Biomass: definition, average composition, evaluation
Biological productivity
Primary production: energy assimilation in phytoindividuals
Phytopopulation productivity
Biocoenosis productivity
Bioproductivity factors: ecological factors (energy, matter, space etc.)
Forest ecosystems productivity
Principal forest ecosystem productivity
Grassland ecosystem productivity
Changes in grassland vegetation, Productivity factors
Various grassland ecosystems productivity.
Seminar’s topic:
Population structure
Phytopopulation descriptors: abundance, density, cover, frequency, aggregation etc
Phytocoenosis descriptors: qualitative and quantitative
Qualitative phytosociological indices: phytoindividual vitality, phenological state
Quantitative phytosociological indices: abundance, dominance, frequency
Measurement of above-ground biomass of tree stratum
Tree stratum biomass calculation: gravimetric method and volumetric method
Measurement of herbaceous stratum density and biomass, in forests
Measurement of root biomass
Measurement of biomass and productivity in grassland ecosystems
Grassland descriptors: pastoral value, specific quality index
Assessment of grassland quality
Measurement of total real productivity.
References
Chifu, T, Alexandrina Murariu, Mustata Gh, 1998, Fotosinteza s productivitatea ecosistemelor,
Ed. Univ. „Al. I. Cuza” Iasi, 468p
Cristea, V., et. al., 1996, Ocrotirea naturii si protectia mediului in Romania. Ed. Cluj University
Press, Cluj-Napoca, 318p.
Cristea, V., et al, 2004, Fitosociologie, Ed. Presa Universitara Clujeana, Cluj-Napoca, 394p
Cristea, V., 1993, Fitosociologie si vegetatia Romaniei,Univ. Babes-Bolyai, Cluj-Napoca
Cristea, V., Fitocenologie si vegetatia Romaniei, 1991, Indrumator de lucrari practice, Univ.
Babes-Bolyai, Cluj-Napoca, 144p
Murariu, Alexandrina, Oana Zamfirescu, 2004, Productivitatea ecosistemelor. Metode practice
de teren si laborator, Ed. Univ. „Al. I. Cuza” Iasi, 159p
Course’s name: Evaluation of Antropic Impact and Environment Balance
CREDITS ECTS: 6
Semester IV
Course’s holder: Reader Professor PhD Victor SURUGIU
Objectives: Appropriation of the sustainable development concepts and principles and of the
environmental legislation.
Attainment of knowledge regarding the Environmental Impact Assessment (EIA) and Strategic
Environmental Assessment (SEA) procedures.
Recommended/obligatory courses: Legislation concerning biodiversity; Practical methods foe
monitoring and evaluation of some plant and animal groups
General topic:
Evolution of the sustainable development concept and of the environmental protection
strategies at the national and international level
33
Legislative framework. EU and Romanian regulations regarding EIA, SEA, free access to the
information and the participation of the public at the decision taking in the case of projects
having environmental effects
Classification of economic and social activities as a function of the potential impact on the
environment
Types of environmental permits. Environmental authorisation. Integrated environmental
authorisation.
Objectives, purposes and steps in the Environmental Impact Assessment
Types, domains and content of environmental audits required in the authorisation process
Monitoring of the projects and environmental audit.
Seminar’s topic:
Environmental Impact Assessment procedure and issuance of environmental permits.
Authorisation procedures for socio-economic activities having environmental impact
Evaluation of environmental risks and measures for reduction of the environmental impact
Procedure for environmental audit
Information and participation of public at the EIA procedure
Study case: Rosia Montana
References
1. Macoveanu, M., 2005. Auditul de mediu. Ed. Ecozone, Iasi.
2. Macoveanu, M., 2005. Metode si tehnici de Evaluation a impactului ecologic. Ed.
Ecozone, Iasi.
3. Rojanschi, V., Bran, F., Diaconu, S., Grigore, F., 2004. Evaluationa impactului ecologic si
auditul de mediu. Editura ASE, Bucuresti.
Teaching methods: Lectures, brainstorming, case study.
Course’s name: Management of Environmental Projects
CREDITS ECTS: 6
Semester IV
Course’s holder: Reader Professor PhD Naela COSTICA
Objectives: Knowing „life cycle” of an project
Knowing the project manager responsibilities
Writing an environmental project.
Recommended/obligatory courses: Biodiversity conservation, Environmental legislation
General topic:
General about projects - What are projects? - Basic features of projects
Project phases (basic processes) - Initiation; Planning/Design/Organisation; Implementing/
Execution/ Construction; Monitoring
Evaluation
Responsibilities and features of project manager: Duties of project manager; Planned approach
Identification and initiation of environmental projects - Project selection; Project aims, purpose
and dimensions; Risks and necessities; Project management team
Planning/projection/Organisation - Establishing the project activities; Work plan achievement;
Logic frame approach (LFA); Resource management; Time management - Gantt Diagram;
Project budget; Funds obtaining/project approval
Implementing/ Execution/ Construction - Work meetings; Communication and information
management; Budget and time management; Conflict management; Management of changes
Seminar’s topic:
Case studies
Example of best practice in project management
Applicative exercises of project writing.
References
Brown Mark, 1998, Project Management, - Hodder & Stoughton General.
Bartram Peter, 1999, The Perfect Project Manager, Random House Business Books.
Baum C. Warren, 1994, The Project Cicle, Library of Congress Cataloging in Publication Data.
Dumitru Oprea, Gabriela Mesnita, 2007, Fonduri Europene pentru Romania in perioada 2007 –
2013, Ed. Sedcom Libris, Iasi.
34
Efraim Turban, Meredith Jack R., Homewood Irwin, 1998, Fundamentals of Management
Science, Boston, Ma.
***, A Guide to the Project management Body of knowledge, 1996, Project Management
Institute.
www.managementul-proiectelor.ro
Teaching methods: Lectures, case study, brainstorming, investigation
¾ MOLECULAR GENETICS
The program began in 1997 and since than it has ensured preliminary training
for PhD accession in the Genetics field, while developing an interdisciplinary and
multidisciplinary research direction that investigates complex and various molecular
aspects of living organism’s functionality. The curriculum for these two years of study is
orientated towards increasing the practical applicability of the accumulated theoretical
knowledge and teaching the graduates how to approach scientific investigations of
cells, animal and vegetal organisms at a molecular level.
The main goal of this master degree program is to train specialists capable to
carry out complete and complex investigations on the structure and functionality of
living organisms, and decipher the molecular mechanisms involved in cell organization
and function under normal and pathological conditions.
The thesis’ main theme is a complex study of different cellular processes at
molecular level.
This Master study program trains the graduates in the following Molecular
Biology fields:
• A good knowledge of the complexity of molecular and cellular mechanisms
involved in gene expression;
• General knowledge of different cellular processes interrelations;
• Nucleic acids and informational molecules study;
• Genome organization analysis in Prokaryotes and Eukaryotes ;
• Human genome study: identifying molecular and chromosomal markers in normal
and pathological states, (with possible applications in molecular diagnostic);
• Transgenic organisms;
• Genome alteration under pathogen and mutagen factor activity;
• Cell cycle and it’s control mechanisms;
• Use of experimental models in mutagenesis study and hereditary information
genetic substrate alteration;
• Bioinformatics and its applications;
• Molecular Genetics study methods;
• Taxonomy, phylogeny and molecular ecology.
The existing material basis allows the study of basic techniques used in
Molecular Biology – nucleic acid isolation and purification, PCR, electrophoresis – as
well as advanced techniques – DNA sequencing, gene expression by RT-PCR.
The students can be involved in scientific research activities within research
projects, under the coordination of Molecular Genetics and Archaeogenetics laboratory
members.
Graduates will have the following qualifications:
¾ Exploration and research qualification – most accumulated knowledge include
multidisciplinary synthesis information, that allow involving the students in scientific
study activities;
¾ Communication (TI&C) and informational technologies qualification, in
molecular biology information analysis and scientific interpretation;
35
¾ communication competency, gained especially with the help of debate
seminaries;
¾ Managerial and decisional qualifications, by encouraging the students to find
answers to new research themes, conceive and implement new research projects.
Legal medicine institutes;
Forensic laboratories;
Research laboratories ;
Teaching in universities of biology, medicine or agronomical studies;
Molecular Biology research institutes;
Diagnostic laboratories;
Phytosanitary and Agro-forestry control laboratories;
Veterinary and food safety, including genetic modified organisms (GMO)
identification laboratories.
36
Faculty of Biology
APROVED
Valid for :
st
1 Year: 2009 - 2010
2nd Year: 2010 - 2011
PROGRAMMES OF STUDY
Specialisation: Master degree – Molecular Genetics
No.
Name of the subject
C
S
L
Credits
Pr
Evaluation type
Colloquium
Exam
1
Gene Expression Control
2
2
0
9
I
2
Biochemistry of Informational Macromolecules
2
0
2
9
I
3
Research Techniques Used For Nucleic Acids
2
0
1
6
I
4
Statistical Methods in Bioinformatics
2
0
2
6
I
8
2
5
30
TOTAL
nd
2
ST
SEMESTER (1
0
4
YEAR)
1
Molecular Biotechnologies in Industry and Medicine
2
0
1
7
II
2
Recombinant DNA Technologies
2
0
1
8
II
3
Human Molecular Genetics and Gene Therapies
2
2
0
8
II
4
Biomodelling: genetics algorithms
2
0
2
7
II
8
2
4
30
TOTAL
rd
nd
3 SEMESTER (2
YEAR)
0
4
1
Molecular Mechanisms of Cell Signalling
2
2
0
6
III
2
Transgenic Animals
2
0
2
10
III
3
Molecular Alteration Involved in Genome Instability
2
0
1
7
III
4
Cellular and Molecular Aspects of Ontogenetic Processes
2
2
0
7
III
8
4
3
30
TOTAL
th
nd
4 SEMESTER (2
0
4
YEAR)
1
Molecular Biology of Cell Cycle
2
0
2
6
IV
2
Transgenic Plants
2
0
2
6
IV
3
Evolution of Gene Fund
2
1
0
6
IV
4
Molecular Ecology and Phylogeny
2
0
1
6
IV
5
Magnum practicum
0
0
6
6
IV
6
(facultative)
0
0
90
5*
IV
8
1
11
30
TOTAL
No.
0
5
No. of classes
Examination
Sem.
Credits
type
C
A
1
2
1
2
28
28
14
14
5
5
Exam
Exam
3
Didactics of Specialty (high school, post-high school and university levels)
3
28
14
5
Exam
4
4
0
42
5
Colloquium
5
2
14
28
5
Exam
38
6
3
1
2
3
4
4
14
28
5
Exam
30
5E+1C
5
Exam
IMPORTANT NOTES:
The credits allocated for the discipline "Practice in research, documentation and elaboration of the final thesis" are not to be taken into account for the
average of the 4th semester.
The students from the promotion 2005 – 2008 (3 years) must attend and promote the pedagogical training’s courses in order to work like teachers in
the high-schools, post-high schools and universities.
The master’s degree in Biology, specialization MOLECULAR GENETICS can be conferred only to students that have obtained 120 credits in the
obligatory disciplines from the hereof syllabus.
39
Course’s name: Gene Expression Control
CREDITS ECTS: 9
Semester I
Course’s holder: Lecturer PhD Lucian GORGAN
Objectives: Thoroughgoing study of genes and their expression.
Gene expression at different informational levels
Regulation of Gene expression.
Gene expression study methods.
Recommended/obligatory courses: General Genetics, Molecular Genetics.
General topic:
Molecular biology – fundamental aspects
The cell, hereditary information stocking model: Somatic and germinal cells; Zygote and epithelial cells
Gene concept: Definition, structure, functions; Supragenic organization of genetic material;
Chromosome, Genome, Genotype, Phenotype; Gene types; Hereditary information phenotypization;
Transcription; Translation; Phenotypization influencing factors; Phenotypization mechanisms
Gene expression concept
Gene expression on DNA level - Transcription control; Operons as functional units; Immune system,
antibodies and antigens; Antibody codifying genes; Hormonal control of gene expression
Chromosomes, gene folding and replication - Types of chromatin; Chromosomes and folding methods;
Information transcription editing; Introns, structure and function; Exons, structure and function;
Information translation control; Polypeptide control, repression and activation
Regulation of gene expression in Prokaryotes - Gene expression control in Prokaryotes; E. coli
chromosome; Operon models; E. coli lac operon; E. coli trp operon; Genome structure in viruses and
plasmids; Transposons in Eukaryotes; Viral influence on gene expression
Regulation of gene expression in eukaryotic cells - Control of transcription initiation; Eucaryotic
chromosome replication; Gene expression control in Eukaryotes; Structural models of Eukaryotic
transcription factors
Seminar’s topic:
DNA synthesis, mechanisms and control
Replication origin and prereplicative complex
Chromatin structure, histone synthesis and nucleosome assembling
Heterochromatin, telomeres and centromeres – structure, functions and study methods
Mitotic division, regulation and control mechanisms
Gene expression activation mechanisms in yeast and bacteria
Activation mechanisms in eukaryotic gene expression
Gene expression regulatory mechanisms
DNA degradation and cell response
Gene expression analysis methods: RT-PCR; Microarray; Blotting
References
Hall M. N., Raff M., Thomas G., 2004 – Cell growth: Control of cell size, Cold Spring Harbor
Laboratory Press.
Morgan O. D., 2007 – The cell cycle, Oxford universitz Press.
Sonenberg N., Hershey J. W. B., Mathews M. B., 2000 – Translational control of gene expression,
Cold Spring Harbor Laboratory Press.
Vaillancourt P. E., 2003 – E. coli gene expression protocol, Humana Press.
Teaching methods: Lectures, debates, case study, modelling – brainstorming
Evaluation: Learning the theoretic knowledge and presenting practical skills typical for the course.
Partial and final evaluation (written and oral presentation).
Course’s name: Biochemistry of Informational Macromolecules
CREDITS ECTS: 9
Semester I
Course’s holder: Professor PhD Dumitru COJOCARU
Objectives: Advance knowledge regarding the chemical structure of proteins and nucleic acids, their
catabolism and biosynthesis, molecular mechanisms of DNA biosynthesis, and cellular regulation of
DNA and protein biosynthesis.
Recommended/obligatory courses: Biochemistry, Metabolism of proteins and nucleic acids,
Enzymology, Genetics.
General topic:
Amino-acids – basic structural units of proteins
Proteins: definition, chemical structure, proprieties, chemical structure, biological role
Protein catabolism - Enzymatic hydrolysis of proteins; Proteolytic enzymes in the digestive system,
stomach, intestine, tissue and blood - Plant proteolytic enzymes; Microbial proteolytic enzymes
Nucleic acids: definition, biological role, nucleic acid catabolism, nucleic acid biosynthesis, molecular
mechanisms of DNA replication
Protein biosynthesis – Recognition; Protein biosynthesis in ribosome (translation): initiation, elongation
and termination of translation; Encoding of genetic information. Codon – anticodon; Specific aspects
regarding protein biosynthesis in micro-organisms; Post-translational modification of proteins;
Antibiotics interactions with ribosome; Chromo-proteins biosynthesis; Porphyrines biosynthesis;
Chlorophyll biosynthesis; Cellular regulation of protein and nucleic acid biosynthesis
Seminar’s topic:
Colorimetric assay for bilirubine concentration
Alantoin assay
Plant urease assay
Creatine and creatine-phosphate determination
Creatine determination
Xanthurenic acid determination
Ehrlich method for urobilinogen determination
Urochrome determination
Yeast DN-ase assay
Yeast RN-ase assay
References
Artenie, Vl. G. – 1991, Biochimie, Ed. Univ. “Al. I. Cuza” Iasi
Artenie, Vl. G., Elvira Tanase – 1981, Practicum de biochimie generala, Ed. Univ. “Al. I. Cuza” Iasi
Cojocaru, D. C. – 1997, Enzimologie, Ed. Gama, Iasi
Cojocaru, C. D., Mariana Sandu – 2004, Biochimia proteinelor si acizilor nucleici, Editura PIM, Iasi
Cojocaru, D. C. – 2005, Enzimologie aplicata, Ed. TEHNOPRESS, Iasi
Dumitru, I. F. – 1967, Lucrari practice de biochimie, Ed. Did. si Ped., Bucuresti
Dumitru, I. F. / 1981, Biochimie, Ed. Did. Si Ped. Bucuresti
Pelmont, Y. – 1992, Enzymes, Presses Universitaires de Grenoble.
Teaching methods: Lectures, debates, modelling – brainstorming
Course’s name: Research Techniques Used For Nucleic Acids
CREDITS ECTS: 6
Semester I
Course’s holder: Professor PhD Ovidiu TOMA
Objectives: Performing methods in research of nucleic acids
Modern techniques of nucleic acids investigations and apparatus.
Recommended/obligatory courses: General chemistry, Structural biochemistry,
biochemistry.
General topic:
DNA structures identification
RNA structures identification
Mutational screening through protein truncation test (PTT)
Nucleic acids electrophoresis
PCR technique
Computer evaluation of nucleic acids through logistical model in 4 parameters
Seminar’s topic:
41
Analytical
One-dimensional electrophoresis of nucleic acids
Bi-dimensional electrophoresis of nucleic acids
DNA and RNA transfer on membranar filters
Postelectrophoretical characterisation
PCR parameters optimisation
Impact of PCR technique on nucleic acids sequences amplification
References
Ausubel F.M. si colab., 1991 - Current Protocols in Molecular Biology. Ed.John Wiley & Sons, vol.1,2,
New York
Cook J., Holtom G.,Lu P., 1990 - Analitical Biochemistry, 190(2), 331-339
Erlich A.H., 1989 - PCR Technology: Principles and Applications for DNA Amplification. Stockton
Press, New York
Freerksen D.L., Shih P.C., Vasta Russell J.F., Horlick R.A.,Yan W.W., 1990 - Analitical Biochemistry,
189(2),163- 168
Hartley J.A., Berardini M.D., Souhami R.L., 1991 - Analitical Biochemistry, 193(1), 131-134
Oerter K.E., Munson P.J., McBride W.O., Rodbard D., 1990 - Analitical Biochemistry, 189(2), 235-243
Ohmiya Z., Kondo Y., Kondo T., 1990 - Analitical Biochemistry, 189(1), 126-130
Sanseau Ph., Tiffoche C., El Kahloun A., Collin O., Roland J.P., Le Pennec J.P., 1990 - Analitical
Biochemistry, 189 (1), 142-148
*** - Trends in Biochemical Sciences. Elsevier Trends Journal, Cambridge
*** - Analitical Biochemistry : Methods in the Biological Sciences. Academic Press Inc.Harcourt Brace
& Co., San Diego.
Course’s name: Statistical Methods in Bioinformatics
CREDITS ECTS: 6
Semester I
Course’s holder: Lecturer PhD student Calin Lucian MANIU
Objectives: Bioinformatics and Bio-modeling, interdisciplinary science.
The purpose and importance of bio-modeling, progress in the field and trends.
Knowledge organization of the main types of biological databases.
Accessing information from biological databases and exploitation for genetic information analysis.
Learning basic skills in using software for DNA/RNA sequence analysis (general parameters and
specific parameters).
Using appropriate statistical methods.
Recommended/obligatory courses: T.I.C. (Information Technology & Communication), Genetics,
Biochemistry, Biophysics, Cell Biology.
General topic:
Genetic alphabet – Words: Introduction; The four-letter genetic alphabet; Biological language words.
The term “k-word” or “k-tuple”; Basic composition. Keyword type k = 1; Probabilities; Probability
distributions; The concept of independent variable; Estimated values and variances; Simulations
based on probability distributions; Keyword type k = 2; Introduction to Markov chains algorithms type;
Conditional probabilities; Markov chain property; Keyword type k = 3. Codon; Keyword type k> 3.
Frequency and distribution of words - Endonucleases restriction; Modeling the number of sites for
DNA restriction; Continuously type variable with a random character; Central limit theorem; Cast and
restriction fragment size.
Physical mapping of DNA macromolecule - The issue of double cleavage. Algorithms; Constucte
production of genomic DNA cloned fragments.
Alignment of DNA sequences in the macromolecule.
Fast methods of alignment: FASTA and BLAST.
Assembly sequences in the DNA macromolecule.
Signals in the DNA macromolecule - Identifying signals in nucleic acid sequences; Entropy and
information content; Signals to genes eukaryotes.
Similar distance and clustering - Measuring similarities and distances early on continuous scales;
Hierarchical clustering-crowded. Interpretations and limitations.
42
Phylogenetic trees – Terminology; Models for change and estimate distances; ML methods (Maximum
likelihood); Statistical evaluation of phylogenetic trees. Problems and limitations.
Comparative genomics - Composition measurements; Transposable elements; Organization of
sequences in chromosomes; Identification of conserved segments and segmental duplication; The
evolution of genome by whole genome duplication; Gene content; Prediction of gene; Exons and
introns statistic; Comparative methods for identifying genes; The content of genes within and between
organisms.
Seminar’s topic:
Introduction to biological databases - General types of databases: Relational database; Objectoriented database; Types of biological databases: Primary databases (GenBank, European Molecular
Biology Laboratory (EMBL) and DNA Data Bank of Japan (DDBJ); Secondary databases (SWISSPROT, PIR, DALI); Biology specialized databases (TAIR, EBI); Interconnections between biological
databases, solutions and limitations; Querying and extracting data contained in biological databases:
Heuristic methods (BLAST and FASTA); Alternative Method Smith-Waterman.
Introduction to use the R program language and environment for advanced statistical analysis and
graphics - The main controls of the R application; Import and export data; Objects types; Elementary
calculations; Statistical applications; Functions. Syntax; Components library; Graphic render.
Parameters.
References
Baxevanis AD, Ouellette BFF (2001) Bioinformatics: A Practical Guide to the Analysis of Genes and
Proteins (2nd edition). New York: Wiley-Interscience.
Campbell AM, Mrázek J, Karlin S (1999) Genome signature comparisons among prokaryote, plasmid,
and mitochondrial DNA. Proceedings of the National Academy of Sciences USA 96:9184–9189.
Dalgaard P (2002) Introductory Statistics with R. New York: Springer-Verlag.
Durbin R, Eddy S, Krogh A, Mitchison G (1998) Biological Sequence Analysis: Probabilistic Models of
Proteins and Nucleic Acids. Cambridge: Cambridge University Press.
Everitt BS, Dunn G (2001) Applied Multivariate Data Analysis. 2nd Ed. Oxford: Oxford University
Press.
EwensWJ, Grant GR (2001) Statistical Methods in Bioinformatics. New York: Springer-Verlag.
Ferguson PL, Smith RD (2003) Proteome analysis by mass spectrometry. Annual Review of
Biophysics and Biomolecular Structure 32:399–424.
Futcher B, Latter GI, Monardo P, McLaughlin CS, Garrels JI (1999) A sampling of the yeast proteome.
Molecular and Cell Biology 19:7357–7368.
Karlin S, Campbell AM, Mrázek J (1998) Comparative DNA analysis across diverse genomes. Annual
Review of Genetics 32:185–225.
Krause A, Olson M (2002) Basics of S-PLUS (3rd edition). New York: Springer-Verlag.
Médigue C, Rouxel T, Vigier P, Hénaut A, Danchin A (1991) Evidence for horizontal gene transfer in
Escherichia coli speciation. Journal of Molecular Biology 222:851–856.
Maindonald J, Braun J (2003) Data Analysis and Graphics Using R. Cambridge: Cambridge University
Press.
Richard C. Deonier, Simon Tavaré, Michael S. Waterman (2005) Computational Genome Analysis: An
Introduction, New York: Springer-Verlag.
Sharp PM, Li W-H (1987) The codon adaptation index a measure of directional synonymous codon
usage bias, and its potential applications. Nucleic Acids Research 15:1281–1295.
Venables WN, Ripley BD (2002) Modern Applied Statistics with S (4th edition.) New York: SpringerVerlag.
Venables WN, Ripley BD (2002) S Programming. New York: Springer-Verlag.
Venables WN, Smith DM, and the R Development Core Team (2002) An Introduction to R.
Bristol:Network Theory, Ltd.
Whittam TS (1996) In Neidhardt FC (Ed. in Chief), Curtiss III R, Ingraham JL, Lin ECC, Low KB,
Magasanik B, Reznikoff WS, Riley M, Schaechter M, Umbarger HE (eds). Escherichia coli and
Salmonella: Cellular and Molecular Biology. Washington, D.C.: ASM Press, pp 2708–2720.
Teaching methods: Lectures, Euristic conversation, Debates, Brainstorming, Case study.
Course’s name: Molecular Biotechnologies in Industry and Medicine
43
CREDITS ECTS: 7
Semester II
Course’s holder: Reader Professor PhD Smaranda VANTU
Objectives: The structural and functional characteristics of plants cultivated “in vitro”
The theoretical and practical aspects of „in vitro” cultivation and the advantages of the unconventional
methods.
Recommended/obligatory courses: General Genetics, Plant Physiology, Biochemistry.
General topic:
The plants - alternative sources of biologically active compounds
The applications of biotechnology in food industry
The applications of biotechnology in chemical industry
The applications of biotechnology in pharmaceutical industry- antiviral, antibacterial, antitumoral
substances (Biosynthesis of podophyllotoxin, paclitaxel, camptothecin)
The plants - alternative systems to produce proteins for therapeutic uses.
Seminar’s topic:
Plant Cell Cultures: Production of Biologically Important Secondary Metabolites from Medicinal Plants
Biotechnology of Solanaceae Alkaloids: A Model and an Industrial Perspective
Plant Biochemistry and Biotechnology of Flavonoide Compounds and Essential Oils
Biotechnological Production of Artemisinin for Malaria Therapy
Production of Therapeutic Antibodies in Plants
References
Anderson, L.A.,Phillipson, J.D., Robers, M.F., Biosynthesis of secondary products by cell cultures of
higher plants, in: Advances in Biochemical Engineering Biotechnology, Fiechter A. (Ed.), Springer
Verlag Berlin
Oliver Kayser, Wim J. Quax, 2007 - Medicinal Plant Biotechnology. From Basic Research to Industrial
Applications
Vantu, S., 2005 - Culturi de celule si tesuturi vegetale in biotehnologie, Edit. Univ. „Al. I. Cuza”, Iasi
Teaching methods: Lectures, modelling – brainstorming
Course’s name: Recombinant DNA Technologies
CREDITS ECTS: 8
Semester II
Course’s holder: Lecturer PhD Mirela Mihaela CIMPEANU
Objectives: Learning about molecular biology techniques
Acquiring knowledge on genetic information manipulation
Acquiring proficiency on recombinant DNA technologies methods.
Recommended/obligatory courses: Biochemistry, Genetics, Molecular biology, Cytology, Microbiology.
General topic:
Fundamentals in molecular biology
Clivage and ligation of DNA molecules
Plasmids and cloning vectors
Bacteriofages and cosmids
Cloning strategies and gene library
Recombinants screening
Recombinant genes expression in Escherichia coli
Sequence analysis
Polymerase chain reaction
Situs mutagenesis
Cloning on eukaryotes
Seminar’s topic:
Biological system used in molecular biotechnologies
Unicellular expression systems
Pluricellular expression systems
Applications
Biological system used in molecular biotechnologies
44
Unicellular expression systems
Pluricellular expression systems
Applications
References
Cimpeanu M., Cimpeanu C., Bara I., 2000 – ADN recombinant, Ed. Corson Iasi
Glick B.R., Pasternak J.J., 1998 – Molecular Biotechnology – Principles and Applications of
Recombinant DNA, 2nd ed., ASM Press, Washington D.C., USA
Lewin B., 1997 – Genes, 6th ed., Oxford University Press, Oxford, New York, Tokyo,
Klug W.S., Cummings M.R., 2000 – Concepts of Genetics, 6th ed., Prentice Hall, Inc., New Jersey,
USA
Old R.W., Primrose S.B., 1994 – Principles of Gene Manipulation – An Introduction to Genetic
Engineering, 5th ed., Blackwell Science, Oxford, UK
Watson J.D., Gilman M., Witkowski J., Zoller M., 1992 – Recombinant DNA, 2nd ed., Scientific
American Books, New York, USA.
Course’s name: Human Molecular Genetics and Gene Therapies
CREDITS ECTS: 8
Semester II
Course’s holder: Lecturer PhD Cristian TUDOSE
Objectives: At the end of the study of this unit, students will be able to:
Identify and analyze the main domains/components of Human Molecular Genetics
Describe the laws and phenomena of heredity and variability applied to humans
Recognize the type of determinism of various normal and abnormal inherited traits and solve practical
problems of transmission for monogenic and polygenic traits
Recognize the features of the most important human genetic diseases and indicate the nowadays
possibilities of prevention and treatment
Demonstrate a minimum level of practical knowledge and abilities in accordance with the laboratory
requirements: human cytogenetic, family inquiry, construction of pedigrees.
Recommended/obligatory courses: Biochemistry, Cellular Biology, General Genetics.
General topic:
Introduction - Short history; Objectives and methods of study; The importance of Human Genetics;
Medical Genetics
Determinism of phenotypic traits - The human being - Genetic and biological individuality; Determinism
of phenotypic traits; The relationship genotype-phenotype-environment; Theoretical and practical
importance of the concept of biological individuality
The structure and organization of DNA - DNA – the molecular base of heredity; Primary and
secondary structure of DNA; The tertiary structure of DNA in humans; The supra molecular structure
of chromatin and chromosome in humans.
The structure, function and location of human genes - The classical and nowadays concept on the
structure of human genes; The classical and nowadays concept on the function of human genes
Expression of Human hereditary information - Molecular mechanisms of gene expression
(transcription, translation); Regulation of gene expression
Transmission of human hereditary information - DNA replication; Cellular fundaments of human
heredity and variability. Mitosis. Meiosis. Fecundation. Cloning; Transmission of human monogenic
traits; Transmission of human polygenic traits
Variability in humans - Genetic recombination; Human mutations; Ecogenetics, Pharmacogenetics,
Toxicogenetics/Pharmacogenomics
Medical genetics - Human genetic diseases: frequency, classification; Congenital anomalies
(malformations, deformations, disruptions); Chromosomal diseases; Monogenic diseases (molecular
diseases, inborn errors of metabolism); Common diseases with genetic predisposition. Cancer
genetics.
General principles of prevention and treatment of human genetic diseases. History. Objectives and
principles. Gene therapy: indications, methods, results, trends and limits. Pharmacogenetics versus
gene pharmacotherapy. Problems of medical genetics ethics in the 21st century.
45
Seminar’s topic:
Human chromosomes. Methods of study. Identification criteria. Characteristics of the human
chromosomes groups. Caryotyping. Polymorphisms. X chromatin. Practical value of human
chromosomes study.
Human molecular cytogenetics techniques (FISH)
Determinism of normal inherited traits, transmission of monogenic and polygenic traits.
Practical value of the study of normal inherited traits
Determinism of human abnormal inherited traits, Family inquiry, Twins study, Pedigrees.
Transmission of human monogenic abnormal traits.
Human chromosome anomalies
Human populations’ genetics.
Techniques of molecular genetics used to detect human monogenic mutations and analyze gene
expression in specialized tissues: DNA extraction, Polymerase Chain reaction (PCR), PCR-based
techniques for monogenic mutations detection, DNA sequencing.
Genetic counseling.
References
Bara I, Cimpeanu Mirela, 2003 – Genetica, Ed. Corson, Iasi
Castilho R.L., Moraes A.M., Augusto E., Butler M., 2008 – Animal cell technology-from
biopharmaceuticals to gene therapy, Taylor and Francis, New York.
Coprean Dina, 1998 – Genetica medicala, Ed. Risoprint, Cluj – Napoca.
Covic M. (sub redactia), 2004 – Tratat de genetica medicala, Polirom, Iasi.
Jorde L, Carey J, 2006 – Medical Genetics, 3rd Edition, Elsevier, New York
Patras Xenia, Tudose C., 2003 – Farmacogenetica, Ed. Tehnopres, Iasi.
Raicu P., 2004 – Genetica generala si umana, Ed. Humanitas, Bucuresti.
Tudose C., Maniu Marilena, Maniu C., 2000 – Genetica umana, Ed. Corson, Iasi.
Teaching methods: Lectures, euristic conversation, debates, case study, experiment, modelling –
brainstorming
Course’s name: Biomodelling: genetics algorithms
CREDITS ECTS: 7
Semester II
Course’s holder: Lecturer PhD Calin Lucian MANIU
Objectives: Bioinformatics and Bio-modeling, interdisciplinary science.
The purpose and importance of bio-modeling, progress in the field and trends.
Knowledge organization of the main types of biological databases.
Accessing information from biological databases and exploitation for genetic information analysis.
Learning basic skills in using software for DNA/RNA sequence analysis (general parameters and
specific parameters).
Recommended/obligatory courses: T.I.C. (Information Technology & Communication), Genetics,
Biochemistry, Biophysics, Cell Biology.
General topic:
The cell - Mitosis and meiosis; Variation and recombination; Genes; The consequence of variation:
evolution; Storing and transmitting information: DNA, RNA, Proteins, Coding; Experimental methods.
Analysis of sequences and microarrays (DNA chips) - Computational Molecular Biology; Fundamental
concepts in molecular biology; Global and local alignment of sequences; A heuristic approach to the
comparison sequences; Comparison of parallel and distributed sequences.
Parallel computing for analyzing gene expression relationships - Significance analysis of gene
expression; Relations in multivariate gene expression; Classification based on gene expression; DNA
fragment assembly using distributed genetic algorithms - Problems in assembling the fragments of
DNA; DNA fragment assembly using GA sequential method. DNA fragment assembly using GA
parallel method; Experimental results and conclusions; Cooperative genetic algorithms and microarray
experiments (DNA chips) - Experiments in microarrays; Rules of association; Multi-objective genetic
algorithms; Multi-objective cooperative genetic algorithms; Experimental results and conclusions.
Phylogenetics - Classification and nomenclature in biology; Fundamental phylogenetic patterns;
Parallel and distributed computations in large-scale construction of phylogenetic trees; Analysis of ML
46
(Maximum likelihood); Phylogenetically estimation parameter; Reconstruction of phylogenetic trees by
the Quartet Puzzling method; Phylogenetic reconstruction of high performance through analysis of MP
(Maximum Parsimony).
Comparative genomics - Composition measurements; Transposable elements; Organization of
sequences in chromosomes; Identification of conserved segments and segmental duplication; The
evolution of genome by whole genome duplication; Gene content - Gene prediction; Exons and introns
statistics; Comparative methods for identifying genes; The content of genes within and between
organizations.
Seminar’s topic:
Biological Databases - PDB (Protein Data Bank) and MMDB (Molecular Modeling Database); Format
and file structure; Viewing structural information; View database structure; Advanced Structural
Modeling; Search for structural similarities.
Using the PAML package software (Phylogenetic Analysis by Maximum likelihood) - Introduction
PAML package applications; Running applications under Microsoft Windows and Linux / UNIX;
Examples of data; Format files containing input data; Format data files containing sequences; File
format for phylogenetic trees and the representation of their topology; Files baseml control; Files
basemlg control; Files codeml control (codonml and aaml) for sequences of codons and amino acid
sequences; Other types of files: evolver, yn00, mcmctree; Models and analysis; Models of nucleotide
substitution; Codon substitution models; Basic models; Branch models; Sites models; Branch-Site
models; Clade models; Amino acid substitution models; Models for combined analysis and data
partition; Reconstruction of ancestral sequences; Search algorithms in phylogenetic trees; Bootstarp
sets data type; Simulation.
Simulare.
References
A. D. Baxevanis, B. F. Francis Ouellette, Bioinformatics, A Practical Guide to the Analysis of Genes
and Proteins, 2nd ed. John Wiley & Sons, Inc. 2001.
A. D. Baxevanis, D. B. Davison, R. D. M. Page, G. Stormo, and L. Stein, Eds., Current Protocols in
Bioinformatics, Wiley and Sons, New York, USA, 2002.
J. Felsenstein, Infering Phylogenies, SinauerAssociates, Sunderland, Massachusetts, 2004.
D. L. Swofford, G. J. Olsen, P. J.Waddell, and D. M. Hillis, Phylogeny Reconstruction, in D. M. Hillis,
C. Moritz, and B. K. Mable, Eds., Molecular Systematics, Sinauer Associates, Sunderland,
Massachusetts, 2nd ed., 1996, pp. 407–514.
J. Felsenstein, Evolutionary trees from DNA sequences: A maximum likelihood approach, J. Mol.
Evol., 17, 368–376, 1981.
G. J. Olsen, H. Matsuda, R. Hagstrom, and R. Overbeek, fastDNAml: A tool for construction of
phylogenetic trees of DNA sequences using maximum likelihood, Comput. Appl. Biosci., 10, 41–48
1994.
O. Trelles, On the parallelisation of bioinformatics applications, Brief. Bioinform., 2, 181–194 2001.
G. M. Amdahl, Validity of the Single Processor Approach to Achieving Large Scale Computing
Capabilities, in American Federation of Information Processing Societies Conference Proceedings:
Spring Joint Computing Conference (AFIPS 1967), Vol. 30, Afips Press, Reston, Va, 1967, pp. 483–
485.
H. A. Schmidt, K. Strimmer, M. Vingron, and A. von Haeseler, TREE-PUZZLE: Maximum likelihood
phylogenetic analysis using quartets and parallel computing, Bioinformatics, 18, 502–504, 2002.
K. Strimmer and A. von Haeseler, Quartet puzzling: A quartet maximum–likelihood method for
reconstructing tree topologies, Mol. Biol. Evol., 13, 964–969, 1996.
J. Sullivan, K. E. Holsinger, and C. Simon, The effect of topology on estimates of amongsite rate
variation. J. Mol. Evol., 42, 308–312, 1996.
Z. Yang, Maximum-likelihood models for combined analyses of multiple sequence data, J. Mol. Evol.,
42, 587–596, 1996.
Z. Yang, PAML: a program package for phylogenetic analysis by maximum likelihood in Computer
Applications in BioSciences 13:555-556, 1997
W. Gropp, S. Huss-Lederman, A. Lumsdaine, E. Lusk, B. Nitzberg,W. Saphir, and M. Snir, MPI: The
Complete Reference. The MPI Extensions, 2nd ed., Vol. 2, The MIT Press, Cambridge,
Massachusetts, 1998.
A. Y. Zomaya, Editor, Parallel Computing for Bioinformatics and Computational Biology, JohnWiley &
Sons, Inc. 2006.
Teaching methods: Lectures, Euristic conversation, Debates, Brainstorming, Case study.
47
Course’s name: Molecular Mechanisms of Cell Signalling
CREDITS ECTS: 9
Semester III
Course’s holder: Lecturer PhD Cristian Sorin CIMPEANU
Acquiring proficiency on cloning techniques.
Recommended/obligatory courses: Biochemistry, Genetics, Molecular biology, Cytology, Microbiology
General topic:
Basics in cell signalling
Cell signalling mechanisms in apoptosis
Extra-cellular matrix level interactions
Oxidative stress
Transcriptional control
Cell signalling in cancer
Cell signalling in inflammation
Seminar’s topic:
Apoptosis – model organisms
Caspase
Caspase activity regulation
„Death” receptors
Apoptosis in pathological states
References
Cimpeanu, Mirela Mihaela, C.S. Cimpeanu, I.I.Bara, 2000 – ADN recombinant. Ed. Corson, Iasi
Guille M., 1999 – Molecular methods in developmental biology, Humana Press.
Morgan O. D., 2007 – The cell cycle, Oxford university Press.
Slack J., 2001 – Essential developmental biology, Blackwell Publishing.
American Books, New York, USA
Course’s name: Transgenic Animals
CREDITS ECTS: 8
Semester III
General topic:
Animal cell culture
Insects cell culture
Expression vectors for mammalian cell
Animal genom manipulation methods
Cloning
Human genom study methods
Genic therapy
48
Seminar’s topic:
Molecular diagnostic
Therapeutic compounds
Vaccines
Pharming
Therapeutical cloning
References
USA
Course’s name: Molecular Alteration Involved in Genome Instability
CREDITS ECTS: 6
Semester III
Course’s holder: Lecturer PhD Sorin Cristian CIMPEANU
Objectives: Organization level and live matter integration concepts’ explanation
The mechanisms of evolution at gene’s level.
Recommended/obligatory courses: General topic:
Genes – structure and functions
Mutations (causes, mechanisms, types) and organisms hereditary system integrity
Physical, chemical mutagen factors, mutations’ induction and mechanisms
DNA repairing mechanisms
Complementing tests
Suppression processes
Gene’s function identification
Genetic analysis.
Seminar’s topic:
Types of mutations
Dominant and recessive mutations utility
Model organisms used in mutations study
Mutagenesis and mutational mechanism
Phenotype versus genotype
References
Laboratory Press.
USA
Morgan O. D., 2007 – The cell cycle, Oxford University Press.
Schatten G., 2006 – Current topics in developmental biology, Academic Press, Elsevier.
Tuan R. S., Lo Cecilia, 2000 – Developmental Biology Protocols, Humana Press.
49
Course’s name: Cellular and Molecular Aspects of Ontogenetic Processes
CREDITS ECTS: 7
Semester III
Objectives: At the end of the study of this unit, students will be able to:
Identify and analyze the main processes/phenomena of ontogenesis
Describe the laws and phenomena of ontogenesis processes and their genetic control
Knowledge of the most important methodologies of ontogenesis study
Demonstrate a minimum level of practical knowledge of laboratory techniques and model systems for
the study of ontogenesis.
Recommended/obligatory courses: Vegetal and animal histo-embriology, Cellular Biology, General
Genetics.
General topic:
Introduction: determinism and general traits of ontogenesis processes, developmental genetics,
experimental embryogenesis, essential techniques for the study of ontogenesis
Model organisms in the study of ontogenesis: the concept of model organism, Drosophila, Xenopus,
Caenorhabditis elegans, zebrafish, mouse, etc
Genetic control of histo- and organogenesis: stem cells and ontogenesis, imaginal disk in Drosophila,
molecular patterns of central nervous system development, molecular patterns of ecto-, mezo- and
endodermic organs development.
Growth, regeneration and evolution: genetic determinism and molecular patterns of growth and aging,
genetic determinism and molecular patterns of regeneration, development and evolution.
Seminar’s topic:
Cellular cycle- molecular patterns and its genetic control; variations and errors in cellular cycle; cellular
death
Biological system used as models in ontogenesis study
Methods of cellular cycle study
Systems of control and signalling pathways in ontogenesis
Genetic control of cellular growth and proliferation
Stem cells and ontogenesis
Cell and tissue transplantation in embryos.
References
Jorde L, Carey J, 2006 – Medical Genetics, 3rd Edition, Elsevier, New York
Schatten G., 2006 – Current topics in developmental biology, Academic Press, Elsevier.
Slack J., 2001 – Essential developmental biology, Blackwell Publishing.
Course’s name: Molecular Biology of Cell Cycle
CREDITS ECTS: 6
Semester IV
Course’s holder: Lecturer PhD Cristian Sorin CIMPEANU
Acquiring knowledge on cell cycle studies.
General topic:
Introduction
Cyclin-dependent kinasis
50
Cyclins
CDK inhibitors
Proteolisis and cell cycle regulation
CDK phosphorilation
Transcription factors
Hormonal control of cell cycle
Cell cycle and environmental stress
Seminar’s topic:
Cell cycle study models; cell proliferation models cellular morphogenesis in fungi, animals and plants
Genetic methods in cell cycle studies
Cell cycle biochemistry
Transcriptional and post-transcriptional regulation
Replication and mitosis
Cell cycle and cell shape
Cell cycle pathology
References
Laboratory Press.
Morgan O. D., 2007 – The cell cycle, Oxford University Press.
Course’s name: Transgenic Plants
CREDITS ECTS: 6
Semester IV
Objectives: Molecular mechanism of transgenesis
methods
The systemic theory point of view in presentation of advantages and limits of transgenesis.
Recommended/obligatory courses: General Genetics, Plant Physiology.
General topic:
The plant cells cultures
The general methods of genetic manipulation in plants
The genetic transformation with plasmid Ti from Agrobacterium tumefaciens
The vector systems derived from Ti plasmid
The transfer of genes through physical methods
The use of “reporter” genes
The manipulation of genes expression in plants
The obtainment of transgenic plants.
Seminar’s topic:
The plants growth improvement through: nitrogen fixation; nitrogenase and hydrogenase;
bio-control of pathogens
The obtainment of pathogen resistant plants
The obtainment of herbicide resistant plants
The obtainment of stress and senescence resistant plants
The genetic manipulation of biochemical pathways of floral pigments biosynthesis
The genetic manipulation in fruits nutritive value improvement
The plants- bioreactors
References
51
USA
Course’s name: Evolution of Gene Fund
CREDITS ECTS: 6
Semester IV
Objectives: Organization level and live matter integration concepts’ explanation
The mechanisms of evolution at gene’s level.
Recommended/obligatory courses: Genetics.
General topic:
Introduction
Individual, population, species: concepts, definitions, examples
Gene, genome, genotype, genofond – organization systems and hereditary information’s integration
Individual variability – natural selection’s action field - Variability’s causes; Variability’s mechanisms;
Mutations; Reproductive isolation
Selection
Hardy-Weinberg law
Genetic drift
Evolution models
Seminar’s topic:
Punctual debate of each chapter from course program
Real or supposed situation of evolution computer modelling.
References
Adams M. D., 2002. The Drosophila Genome, Science 2000, martie 24; 287 (5461): 2185 - 2195,
Biodavidson, Russell Genetics, p.491.
Arnheim, N., Taylor, Ch.E., 1969. Non-Darwinian Evolution: Consequences for Neutral Allelic
Variation. Nature, 223, 5209, 900-903
Bara, I.I., 1973.Studiu asupra biologiei populatiilor unor specii apomictice si sexuate inrudite.Teza de
doctorat, Facultatea de Biologie, Universitatea Bucuresti.
Bara, I.I., Ghiorghita, G., 1980. Din enigmele evolutiei (Apomixia si rolul ei in evolutie). Editura
Stiintifica si Enciclopedica, Bucuresti.
Bara I., Corneanu G.(sub redactia), Fraley L., Gottschalk W., Imreh St., Lazanyi A., Nedelcu C.,
Whicker W., 1989. Elemente de radiobiologie vegetala. Ed. Ceres, Bucuresti.
Bara, I.I., 1989. Reproducerea, factor al evolutiei plantelor. Editura Academiei, Bucuresti.
Bara, I. I., 1996. Vademecum in genetica. Editura CORSON, Iasi.
Bara, I.I., Cimpeanu, M. Mirela, 2003. Genetica. Editura CORSON, Iasi
Botnariuc, N., 1976. Conceptia si metoda sistemica in biologia generala.Editura Academiei Romane,
Bucuresti
Botnariuc, N., 1992. Evolutionismul in impas ? Editura Academiei Romane, Bucuresti.
Botnariuc,N., 1999. Evolutia sistemelor biologice supraindividuale. Editura Universitatii Bucuresti.
Cook, L.M., 1976.Population Genetics. Chapman and Hall, A Halsted Press Book London, John Wiley
& Sons, Inc., New York
Creed, E.R., 1971. Ecological Genetics and Evolution. Essays in Honour of E.B. Ford.Blackwell,
Oxford.
Crow, J.F., Kimura, M., 1970. An Introduction to Population Genetic Theory. Harper and Row, New
York.
52
Crow, J.F., 1972. The dilemma of nearly neutral mutations: How important are they for evolution and
human welfare ? J. Heredity, 63, 306 - 316.
Crow, J. F., 1995. Spontaneous mutation as a risk factor. Exp. Clin. Immunogenet. 12: 121 - 128.
Dobzhansky, T., 1970. Genetics of the evolutionary process. Columbia University Press, New York.
Falconer, D. S., and T. F. C. Mackay, 1996. Introduction to Quantitative Genetics. 4th ed. Longman
Scientific and Technical, Essex, UK.
Raicu P., Stoian V., Nicolaescu M., 1974. Mutatiile si evolutia. Editura Enciclopedica, Bucuresti..
Raicu,P., Gorenflot, R., 1980.Cytogénétique et évolution. Editura Academiei Romane, Bucuresti.
Simpson, G., G., 1951. The meaning of evolution.New American library, New York.
Course’s name: Molecular Ecology and Phylogeny
CREDITS ECTS: 6
Semester IV
Objectives: The studying bases substantiation in molecular ecology and phylogeny
The experimental models development used in molecular ecology and phylogeny
The importance and relevance of molecular studies applicable in ecology, phylogeny and
phylogeography
The development of molecular concepts about systematic and evolutive aspects.
Recommended/obligatory courses: General Ecology, Genetics.
General topic:
Molecular Ecology as a concept
Molecular bases of evolution
Evolutive modifications in Amino acids and DNA sequences
Synonym and non-synonym nucleotidic substitutions
Comportamental Ecology’s molecular aspects
Genetic diversity in natural populations
Metapopulational genetics
Molecular and adaptative variations
Phylogeny and phylogeography
Genetics in conservative biology
Microbial ecology
Molecular ecology of modified genetic organisms
Gene’s horizontal flow in nature
Practical aspects of molecular ecology.
Seminar’s topic:
Molecular markers used in phylogeny and phylogeography
Applied phylogeography
Practical aspects of molecular ecology
Techniques of sampling and samples preparation
Analysis methods of hereditary information support
Identification on molecular bases of species, individuals and sex
Phylogenetic trees – types, methods and models
Phylogenetics inference and distance based methods
Evolutive distances estimation and amino acids substitution
Parsimony theory based methods and models
Tree’s accuracy and statistical methods
Molecular clock and linear trees
Ancestral sequences of amino acids and nucleotides
Genetic polymorphisms and evolution
References
Beebee T., Rowe G., 2005 – An introduction to molecular ecology, Oxford University Press.
Martins P. Emilia, 1996 – Phylogenies and comparative method in animal behaviour, Oxford University
Press. Nei M., Kumar S., 2000 – Molecular evolution and Phylogenetics, Oxford University Press.
53
Semple C., Steel M. A., 2003 – Phylogenetics, Oxford University Press.
¾ MICROBIAL AND CELLS BIOTECHNOLOGIES
The research in biotechnology in our country comprises a wide range of fields, which
reflects both the interest of the society in microbial biotechnologies, and the great
opportunities provided by this scientific field with an extremely rapid development.
Microbial biotechnology has become a distinct area of study in our faculty
particularly as a result of its possible applications and its potentiality to help solving concrete
problems of the economy. The Master’s Degree Programme was initiated in 1999 and has
had as a main objective the training of specialists capable of complex and comprehensive
approach of the following issues:
biotechnologies used to obtain biologically active substances;
use of the inherent capacity of micro-organisms for the bioremediation of soil, air and
water quality, and the biodegradation of xenobiotics;
use of agricultural, industrial, and municipal waste to obtain the biomass and by-products
of microbial metabolism;
technologies for the production of bio-fuels;
use of advanced technologies with applications in animal husbandry, aquaculture, and
apiculture;
technologies for the production of bio-fertilizers used to increase crop yield;
implementation of novel methods for monitoring air, water, and soil quality using
molecular biotechnologies.
The dissertation paper’s topic represents one study on the impact of microbial and
cellular biotechnologies on the development of the various industrial, agricultural, medical, or
other fields.
Particular attention is paid to the master’s students’ training in scientific research,
which includes the following:
• attracting the master’s students showing interest in different areas of biotechnology
by actual research activities, together with the instructors, to carry out individual or
collective research projects, research grants or contracts with economic beneficiaries etc.;
• arouse the research students’ interest in taking part in student scientific sessions
or in other national and international events.
The graduates will acquire extensive theoretical and practical knowledge on the following:
• microbial biodegradation and biodeterioration;
• water purification of different pollutants of synthetic and natural origin, soil
bioremediation;
• bioconversion of the resources of waste plant biomass and production of bioenergy;
• secondary oil recovery and biomining of metals from poor deposits;
• production of biofertilizers used to increase crop yields and generate good quality,
ecologically pure food products;
• production of effective preparations with anti-tumour, antiviral, antimicrobial action,
new generation vaccines, as well as methods for the early diagnosis of diseases;
• making classic microbial biotechnologies profitable using the methods of genetic
engineering.
medical laboratories;
veterinary laboratories;
54
food industry laboratories;
chemical industry laboratories,
pharmaceutical industry laboratories;
cleaning plants for the municipal and industrial waste water;
environmental protection agencies;
institutes of public health;
research laboratories in colleges or universities;
higher education institutions teaching biology, medicine, agronomy etc.
55
Faculty of Biology
APROVED
Valid for :
1st Year: 2009 - 2010
2nd Year: 2010 - 2011
PROGRAMMES OF STUDY
Specialisation: Master degree – Microbial and cells biotechnologies
No.
Name of the subject
C
S
L
Credits
Pr
Evaluation type
Colloquium
Exam
1
Theoretical Basis of Microbial Biotechnologies
2
0
0
6
I
2
Biotechnologies for the Obtaining Biologic Active Substances
1
0
2
6
I
3
Methods and Processing in Biotechnologies
2
0
0
6
I
4
Vegetal Cell Cultures in Biotechnologies
2
0
2
6
I
5
Biostatistics
1
2
0
6
I
8
2
4
30
TOTAL
nd
2
ST
SEMESTER (1
0
5
YEAR)
1
Applied Enzymology
1
0
2
6
II
2
Biodegradation and Microbial Biodeterioration
2
0
0
6
II
3
Molecular Biotechnologies
1
0
2
6
II
4
Transgenic Organisms
2
0
1
6
II
5
Biomodelling
1
2
0
6
II
7
2
5
30
TOTAL
rd
nd
3 SEMESTER (2
YEAR)
0
5
1
Microbial Biotechnologies for Used Waters
2
0
2
8
III
2
Food Biochemistry
2
0
2
8
III
3
Enzymatic biotechnologies
2
0
1
7
III
4
Animal Cell Cultures in Biotehcnology
1
0
2
7
III
7
0
7
30
TOTAL
th
nd
4 SEMESTER (2
0
4
YEAR)
1
Gene manipulation in biotechnologies
2
2
0
6
IV
2
Biotechnologies Used in Immunology
2
0
2
6
IV
3
Microbial Bioconversions
2
0
2
6
IV
4
Biochemistry of Microorganism Metabolites
2
0
0
6
IV
5
Magnum practicum
0
0
2
6
IV
6
(facultative)
0
0
90
5*
IV
TOTAL
8
2
6
30
No.
1
2
0
5
No. of classes
Examination
Sem.
Credits
type
C
A
Didactics of Specialty (high school, post-high school and university
levels)
1
2
28
28
14
14
5
5
Exam
Exam
3
28
14
5
Exam
4
4
0
42
5
Colloquium
5
2
14
28
5
Exam
3
57
6
3
1
2
3
4
4
14
28
5
Exam
30
5E+1C
5
Exam
IMPORTANT NOTES:
The credits allocated for the discipline "Practice in research, documentation and elaboration of the final thesis" are not to be taken into account
for the average of the 4th semester.
The students from the promotion 2005 – 2008 (3 years) must attend and promote the pedagogical training’s courses in order to work like
teachers in the high-schools, post-high schools and universities.
The master’s degree in Biology, specialization MICROBIAL AND CELLS BIOTECHNOLOGIES can be conferred only to students that have
obtained 120 credits in the obligatory disciplines from the hereof syllabus.
58
Course’s name: Theoretical Basis of Microbial Biotechnologies
CREDITS ECTS: 6
Semester I
Course’s holder: Professor asoc. PhD Octavita AILIESEI
Objectives: Knowing the main developing strategies in microbial biotechnologies
Looking into the newest information about biotechnology and bio-industry
Presentation of modern selection strategies for micro-organisms with biotechnological value.
Recommended/obligatory courses: General Microbiology, Microbial biotechnologies, Biochemistry,
Genetics.
General topic:
Introduction
Biotechnology: present and perspectives. Classic and modern biotechnologies
Developing strategies in microbial biotechnologies - Modernization of fermentative process; Biomedicine and pharmacology; Agriculture and food industry; Energy production; Residual biomass
conversion; Pollution fighting; Fermentative process modelling
Substances produced using biotechnological processes
Biotechnologies and bio-industry: present and perspectives
Biotechnological processes – nature and variety
Micro-organisms used as catalytic agents
Physiology of micro-organisms with biotechnological importance - Nutrient requirements and growth
aspects
Conversion pathways of nutrient sources - Cathabolic, anabolic, amphibolic and anaplerotic pathways
Methods and systems used for microbial growth - Continuous growth systems; Discontinuous growth
systems
Traditional sources for micro-organisms used in microbial biotechnologies
Modern strategies for isolation of micro-organisms from different environments
References
Bourgaize, D., Jewell, T.R., Buiser, G.R., 2000 – Biotechnology, Benjamin/Cummings, Addison
Wesley Longman, San Francisco.
Dunca Simona, Octavita Ailiesei, Erica Nimitan, Stefan Marius, 2004 – Microbiologie aplicata – Ed.
Tehnopress, Iasi.
Dunca Simona, Octavita Ailiesei, 2004 – Biologia termoactinomicetelor– Ed. Tehnopress, Iasi.
Glazer, N., A., Nicaido, H., 1995 – Microbial Biotechnology - W.H. Freeman and Company, U.S.A
Jurcoane Stefana, 2000 – Biotehnologii- Fundamente, Bioreactoare, Enzime - Ed. Tehnica, Bucuresti.
Jurcoane Stefana, 2004 – Tratat de Biotehnologie, vol.I, Ed. Tehnica, Bucuresti.
th
Madigan, M., Martinko, J., Parker, J., 2000 – Brock Biology of microorganisms, 8 . ed., Prentice Hall,
Inc. Simon & Schuster, Viacom Company, New Jersey.
Nimitan, Erica, 1992 – Biotehnologii microbiene - Ed. Univ. “Al.I. Cuza”, Iasi
Popa Lidia, 1987 – Microbiologie industriala. Lucrari practice - Fac. de Biologie, Bucuresti.
Scriban, R.,1993 – Biotehnologie - Ed.4., Tech.Doc. Lavoisier, Paris.
Course’s name: Biotechnologies for the Obtaining Biologic Active Substances
CREDITS ECTS: 6
Semester I
Course’s holder: LecturerPhD Marius STEFAN
Objectives: Knowing the theoretical basis of biological substances production using microbial
biotechnologies.
Acquiring new information about antibiotics and microbial enzymes production..
Recommended/obligatory courses: General Chemistry, Biochemistry, General microbiology,
Imunobiology.
General topic:
Active biological substances: definition, history and perspectives
Implication of micro-organisms in bio-industry development
Main types of micro-organisms involved in active biological substances production
Biotechnological processes used for alcohol, organic acids and amino acids production - Alcohol
biotechnology; Acetic acid and citric acid biotechnology; Amino acids biotechnology – lysine and
glutamic acid production
Antibiotics biotechnology - Antibiotics – definition, classification and producing micro-organisms;
Biotechnology for β lactam antibiotics production; Biotechnology for oligosaccharide antibiotics
production; Biotechnological processes used for microbial biomass production; Biotechnology for dried
pressed yeast production
Biotechnologies used for microbial enzymes production - Biotechnology for α amylases production;
Biotechnology for proteases production.
Seminar’s topic:
Main micro-organisms used in industry: bacteria, actinomycetes, micromycetes
Yeasts used in biotechnologies: Saccharomyces cerevisiae, Saccharomyces cerevisiae var.
ellipsoideus, Rhodotorula rubra, Candida utilis
Laboratory techniques used for yeast metabolic characteristics analysis
Yeast cell glycogen assay
Budding capacity determination
Live/dead cell ratio determination
Methods used for determination of yeast sporulation capacity
Isolation and selection of α amylase producing bacteria
Isolation and selection of antibiotics producing actinomycetes.
References
Dragan-Bularda, M, 2000 – Lucrari practice de microbiologie generala, Editura Univ. Babes-Bolyai,
Cluj-Napoca.
Dunca Simona, Octavita Ailiesei, Erica Nimitan, Stefan Marius, 2004 - Microbiologie aplicata Ed.Tehnopress, Iasi.
Glazer, N., A., Nicaido, H., 1995 – Microbial Biotechnology, W.H.Freeman and Company, U.S.A.
Johnson, T.R., Case, C.L., 1998 – Laboratory experiments in microbiology – The Benjamin Cummings
Publishing Company, Inc.
Moo-Young, M., 1985 – Comprehensive Biotechnology, vol.1, Pergamon Press, Oxford.
Scriban, R.,1993 – Biotehnologie,ed.4., Tech.Doc. Lavoisier, Paris.
Norrell, S.A., Messley, K.E., 1997 – Microbiology laboratory manual, Principles and applications –
Prentice Hall, Upper Saddle River, New Jersey.
Raicu, P., 1990 – Biotehnologii moderne, Ed. Tehnica, Bucuresti.
Teaching methods: Lectures, explication, demonstration, brainstorming, euristic conversation,
experiment, observation
Course’s name: Methods and Processing in Biotechnologies
CREDITS ECTS: 6
Semester I
Objectives: Performing biotechnological methods in research and applicative processes;
Modern techniques of biotechnological investigations and apparatus.
Recommended/obligatory courses: General chemistry, Structural biochemistry, Analytical
biochemistry, Biotechnologies.
General topic:
Basic techniques in biotechnology
Technology of bioreactor
Isolation techniques
Especially techniques
Seminar’s topic:
Electrophoresis
60
Postelectrophoretical characterisation
Expression and biotechnological productions
Microbian sensors
Cells and tissue cultures techniques
Technology of bioreactor
References
Bajaj, Z.P.S. (1985) Biotechnology in agriculture and forestry (Berlin: Springer Verlag)
Dixon, R.A.(ed.) (1985) Plant cell culture: a practical approach (Oxford: IRL Press)
Fowler, M.W., Warren, G.S. (1992) Plant biotechnology (Comprehensive biotechnology, Second
Supplement) (Oxford: Pergamon)
Kingsman, S.M., Kingsman, A.J. (1988) Genetic engineering-an introduction to gene analysis and
exploitation in eucaryotes (Oxford: Blackwell Scientific Publications)
Kleber, H.-P.,Schlee, D., Schopp, W. (1990) Biochemisches Praktikum(Jena: Gustav Fischer Verlag)
Schroder, H. (1991) Mikrobiologisches Praktikum (Berlin: Volk und Wissen Verlag)
Schweizer, M. (1997) Methods in Biotechnology (London: Taylor&Francis Ltd.)
Toma O., Piriianu G, (2001) Biotehnologie: metode & procesare, Ed. Arc 2000, Bucuresti, 84 pg.
Toma O., 2008 – Metode si procesare in biotehnologie. Casa Editoriala Demiurg, Iasi, 80 pg.
Teaching methods: Lectures, euristic conversation, case study, video-projection
Course’s name: Vegetal Cell Cultures in Biotechnologies
CREDITS ECTS: 6
Semester I
The comparative study of ontogenesis “in vivo” and “in “in vitro”
methods.
General topic:
Plant cells, tissues and organ cultures- definition and history
“In vitro” regeneration- biotechnological alternative in agriculture and industry - Plant cell totipotency;
Morphogenetic programmes; Molecular aspects of regeneration “in vitro”; The role of phytohormones
in regeneration
The present and future in new genotypes obtainment - Somaclonal variability; “In vitro” mutagenesis;
Somatic hybridization; Transgenic plants
Practical applications of cell and tissue cultures - Micropropagation and cell cloning; The haploid
plants obtainment; Virus free plants; “In vitro” fertilization; The embryo cultures; The endosperm
cultures; The secondary metabolites biosynthesis in suspension cultures; The improvement of
biosynthetic capacity – elicitation; Hairy roots- cultures
Seminar’s topic:
The initiation of in vitro cultures
The cultures media
The surface and submerse cultures
“In vitro” regeneration
The isolation of protoplasts.
The protoplasts fusion
The cytogenetically analyses of mitotic chromosomes in callus cultures
The histological methods of callus structure
The biochemical methods of secondary metabolites biosynthesis in suspension cultures
The elicitation of suspension cultures
The presentation of students papers based on recommended bibliography.
References
Alberts B., Bray D., Lewis J., Raff J., Roberts K., Watson J., 1983 – Special Features of Plant
Cells, In Molecular Biology of the Cell, Garland Publishing
61
Bhojwani S., Razdan M. K., 1996 – Plant Tissue Culture :Theory and Practice, In:developments in
Crop Science, Elsevier Amsterdam, Oxford, New York
Chrispeels, M.J., Sadava, D.E., 2003 - Plants, Genes and Crop Biotechnology, Jones and Bartlett
Publishers
George, E. F.; Hall, M.A. 2008 - Plant Propagation by Tissue Culture
Jaime A., Texeira da Silva 2006 - Floriculture, Ornamental and Plant Biotechnology
Kirti, P.B. 2008 - Handbook of New Technologies for Genetic Improvement of Legumes
Tesule E.,1993 – Biotechnologie et Amelioration des Plantes. In Biotechnologie, Shiban R(Ed.)
Vantu, S., Bara, I., Toma, O. (1998) - Culturi in vitro. Tehnici de laborator, Edit. Corson
Vantu, S.(2005) - Culturi de celule si tesuturi vegetale in biotehnologie, Edit. Univ. „Al. I. Cuza”, Iasi
Teaching methods: Lectures, seminars, euristic conversation, case study, video-projection
Course’s name: Biostatistics
CREDITS ECTS: 6
Semester I
General topic:
Testing statistical hypotheses and scientific methodology: Testing hypothesis concerning the mean of
a single population (t (Student) test for one sample); statistical decision-making.
Comparison of 2 independent samples: t (Student) test for independent observations; Mann-Whitney
test.
Seminar’s topic:
Testing hypothesis concerning the mean of a single population: t (Student) test for one sample –
exercises.
References
Bailey, T.J.N. (1981): Statistical Methods in Biology. Editia a II-a. Ed. Cambridge University Press.
62
Longman.
Publishers.
Iosifescu M., Moineagu C., Trebici V.,Ursianu E. (1985): Mica enciclopedie de statistica. Ed. Știintifica
si Enciclopedica, Bucuresti
Snedecor, W.G. (1968): Metode statistice aplicate in cercetarile de agricultura si biologie (traducere
din limba engleza). Bucuresti.
Zamfirescu, S.R., Zamfirescu, O. (2008) Elemente de statistica aplicate in Ecologie. Ed. Univ. „Al.I.
Cuza” Iasi.
Course’s name: Applied Enzymology
CREDITS ECTS: 6
Semester II
Course’s holder: Lecturer PhD Elena CIORNEA
Objectives: To familiarize students with general notions that refers to nomenclature, classification and
enzymes structure and, respectively, enzymatically cofactors, their properties, cinetics of enzymatically
reactions, regulation of enzymatically activity and notions of immobilization enzyme concept,
determination of optimal conditions of immobilization and practical utilization of immobilizated
enzymes.
Recommended/obligatory courses: General Chemistry, Biochemistry, Enzymology.
General topic:
The course is structured per chapters that refer to nomenclature, classification and enzymes structure
and, respectively, enzymatically cofactors, their properties, cinetics of enzymatically reactions,
regulation of enzymatically activity and notions of immobilization enzyme concept, sources of industrial
interest enzymes, obtains of industrial enzymes, utilization of enzymes in industry.
Seminar’s topic:
Separation and purification of catalase;
Separation and purification of bacterial urease;
Separation and purification of invertase from cellulose fibers;
Separation and purification of alcooldehidrogenase from malt;
Inclusion of Saccharomyces cerevisiae cells in agar gel.
References
Cojocaru, D. C. – 2005, Enzimologie practica, Ed. TEHNOPRESS, Iasi
Cojocaru, D.C., Zenovia Olteanu, Elena Ciornea, Lacramioara Oprica, Sabina Ioana Cojocaru, 2007 Enzimologie generala, Ed. Tehnopress, Iasi
Nuta, Gh., Busneag, C. – 1977, Investigatii biochimice, Ed. Did. si Ped. Bucuresti
Pelmont, Y. – 1992, Enzymes, Presses Universitaires de Grenoble
Teaching methods: Lectures, explication, demonstration, modelling, brainstorming, euristic
conversation, experiment and observation.
Course’s name: Biodegradation and Microbial Biodeterioration
CREDITS ECTS: 6
63
Semester II
Course’s holder: Professor asoc. PhD Octavita AILIESEI
Objectives: Comparative approach of biodegradation and bio-deterioration concepts
Looking into different substrate modifications induced by micro-organisms
Knowing the microbial agents involved in different substances and materials biodegradation
Presentation of ecological consequences of accumulation phenomenon.
Recommended/obligatory courses: General Microbiology, Microbial Biotechnologies, Biochemistry,
Genetics.
General topic:
Biodegradation and bio-deterioration concepts
Substrate modifications induced by micro-organisms - Physical modifications; Chemical modifications;
Impurification and tainting; Functional modifications
Promoter factors for biodegradation processes
Biodegradation of hydrocarbures and micro-organisms involved in this process - Oil biodegradation
Obtaining bacteria with high degradative properties - Rubber bio-deterioration; Paints bio-deterioration
Vegetal tissue degradation associated with microbial thermogenesis
Bacterial corrosion of metals - Anaerobic bacterial corrosion; Oxidative bacterial corrosion
Direct and indirect metal biosolubilisaton
Microbial degradation of xenobiotics - Co-metabolism in environment
Genetic basis of xenobiotics microbial degradation
Causes of degradation resistance - Molecules size; Molecules structure; Missing of enzymatic
equipment necessary for biodegradation; Pollutant incapacity to induce degradative enzyme synthesis
Ecological consequences of xenobiotic presence in nature - Toxicity to microorganisms;
Bioaccumulation phenomenon.
References
Betts W. B., 1991 – Biodegradation Natural and Synthetic Materials. Springer-Verlag.
Dagley S., 1987 – Lessons From Biodegradation, Annu. Rev. Microbiol. 41: 1 – 23.
Glazer, N.A., Nicaido, H.,1995 – Microbial Biotechnology, W.H. Freeman and Company,
U.S.A.
Koestler, R.J., Koestler, V.H., Charola, A.E., Nieto-Fernandez, F.E., 2004 - Art, Biology, and
Conservation - Biodeterioration of Works of Art, Published by The Metropolitan Museum of Art, 576 p.
White G.F., 1994 – Pollutants biodegradation, Microbiology, 140: 685.
Zarnea, G., 1994 – Tratat de microbiologie generala, vol. V, Ed. Academiei Romane, Bucuresti
Course’s name: Molecular Biotechnologies
CREDITS ECTS: 6
Semester II
Course’s holder: Lecturer PhD Cristian CIMPEANU
Acquiring knowledge on genetic information manipulation.
General topic:
Basics in molecular biotechnologies
Genetically engineered organisms - methods
Risk factors in using genetic modified organisms
Molecular biotechnology in agriculture and food industry
Applications in chemical and pharmaceutical industry.
Seminar’s topic:
Reviews presentation, prepared by students
References
Alberts B., Bray D., Lewis J., Raff J., Roberts K., Watson J., 1983 – Special Features of Plant
Cells, In Molecular Biology of the Cell, Garland Publishing
Bhojwani S., Razdan M. K., 1996 – Plant Tissue Culture :Theory and Practice, In:developments in
64
Chrispeels, M.J., Sadava, D.E., 2003- Plants, Genes and Crop Biotechnology, Jones and Bartlett
Publishers
Cimpeanu M., Cimpeanu C., Bara I., 2000 – ADN recombinant, Ed. Corson Iasi
USA
Vantu, S., Bara, I., Toma, O., 1998 - Culturi in vitro. Tehnici de laborator, Edit. Corson
nd
Watson J.D., Gilman M., Witkowski J., Zoller M., 1992 – Recombinant DNA, 2 ed., Scientific
Course’s name: Transgenic Organisms
CREDITS ECTS: 6
Semester II
General topic:
Animal cell culture
Cloning
Genic therapy
Seminar’s topic:
Vaccines
Pharming
Therapeutically cloning
References
USA
65
Course’s name: Biomodelling
CREDITS ECTS: 6
Semester II
Course’s holder: LecturerPhD student Calin Lucian MANIU
Objectives: Bioinformatics and Bio-modelling, interdisciplinary science.
The purpose and importance of bio-modelling, progress in the field and trends.
Knowledge organization main types of biological databases.
Accessing information from biological databases and exploitation to modelling complex molecular
structures.
Learning basic skills in using bio-modelling software designed (general parameters and specific
parameters).
Recommended/obligatory courses: T.I.C. (Information Technology & Communication), Biochemistry,
Biophysics, Cell Biology, Genetics.
General topic:
Introduction to biological databases - Types of databases; Relational database; Object-oriented
databases; Primary databases (GenBank, European Molecular Biology Laboratory (EMBL) and DNA
Data Bank of Japan (DDBJ); Secondary databases (SWISS-PROT, PIR, DALI); Specialized biological
Databases (TAIR, EBI); Interconnections between biological databases, solutions and limitations.
Query and data mining of existing biological databases: Heuristic methods (BLAST and FASTA);
Alternative Method Smith-Waterman; PDB file format (Protein Data Bank); mmCIF file format
(macromolecular Crystallographic Information File); Other data structures (NMR-specific
BioMagResBank and NDB-Nucleic Acid Database).
Molecular computational biology - Introduction. Basic concepts in computational biology; A heuristic
approach to the comparison of biological sequences; Comparison of parallel and distributed
sequences.
Protein folding - Proteins folding. Method of parallel replication of molecular dynamics processing;
Method of dynamic replication of molecular transformations; Protein folding based on the method of
replicating the dynamics of molecular transformations; Completion of protein structure using the
method of replicating the dynamics of molecular transformations; Parallel evolutionary algorithms to
detect protein structures.
Seminar’s topic:
Bioinformatics and bio-modelling - Information technology, hardware; Central processing unit,
generation and characteristics; Graphics processing unit, generation and characteristics. Computer
classification; Computer networks, parallel processing of data; Internet; Information technology,
software - Operating Systems; Organization and data management to the most common operating
systems: Microsoft Windows and Unix / Linux; Special programs for bio-modelling; Bio-molecular
complex structure prediction programs; Programs for sequences analysis and management; Programs
for reaction paths predictions and analysis; Programs for query and retrieval of necessary data from
biological databases;. Bio-molecular structure viewer programs.
Introduction to biological databases; General types of databases - Relational database; Objectoriented database; Types of biological databases: Primary databases (GenBank, European Molecular
Biology Laboratory (EMBL) and DNA Data Bank of Japan (DDBJ); Secondary databases (SWISSPROT, PIR, DALI); Specialized Biological Databases (TAIR, EBI); Interconnections between biological
databases, solutions and limitations; Querying and extracting data contained in biological databases:
Heuristic databases (BLAST and FASTA); Alternative Method Smith-Waterman.
Introduction to the program NAMD (Scalable Molecular Dynamics), a simulation program for
biomolecular complex and dynamic molecular systems, algorithms based on the interactions between
atomic force fields, configuration parameters, input and output files. The X-PLOR program used to
generate input files witch containing the data describing the molecular system to be simulated by
NAMD.
Introduction to Program VDM (Visual Molecular Dynamics), analysis and visualize files generated by
NAMD. Basic commands and parameters. Representation of a known protein molecules. Search and
retrieval of a .pdb file (Protein Data Bank) from the databases described above. Analysis and visualize
the file. Extracting a file mmCIF (macromolecular Crystallographic Information File). Analysis and
visualize the file.
Create .psf files (protein structure file), using the .pdb source files from biological databases presented
above. Preparing data for simulation: Setting the main parameters of the NAMD simulation program.
Calculation parameters for wan der Waals interactions and electrostatics. The test for interaction
66
distance. Overall electrostatic integration phase; Configuring additional parameters of the NAMD
simulation program: constraints and restrictions, energy minimization, balance temperature control,
pressure control, limiting conditions, analysis and application of external force (constant forces, an
external electric field, motion constraints, rotational constraints) calculation of free energy for
conformational changes, the calculation of interference adaptive forces.
Prediction of genes and promoters: Algorithms and programs for gene prediction in prokaryotes and
eukaryotes; Algorithms and programs for prediction of promoters and regulators in prokaryotes and
eukaryotes.
Molecular Phylogenetics: Fundamentals of phylogenetics, terminology; Molecular evolution and
molecular phylogeneticl Types of phylogenetic trees; Methods and programs for phylogenetic trees
constructions; Evaluation of the constructed phylogenetic trees.
References
Altschul, S. F., Boguski, M. S., Gish, W., and Wootton, J. C. 1994. Issues in searching molecular
sequences databases. Nat. Genet. 6:119–29.
Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J. 1997.
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic
Acids Res. 25:3389–402.
Apweiler, R. 2000. Protein sequence databases. Adv. Protein Chem. 54:31–71.
Bergeron B. 2003. Bioinformatics Computing. Prentice Hall PTR
Blaschke, C., Hirschman, L., and Valencia, A. 2002. Information extraction in molecular biology. Brief.
Bioinform. 3:154–65.
Chen, Z. 2003. Assessing sequence comparison methods with the average precision criterion.
Bioinformatics 19:2456–60.
Dubchak, I., and Pachter, L. 2002. The computational challenges of applying comparative-based
computational methods to whole genomes. Brief. Bioinform. 3:18–22.
Geer, R. C., and Sayers, E.W. 2003. Entrez: Making use of its power. Brief. Bioinform. 4:179–84.
Graur, D., and Li, W., H. 2000. Fundamentals of Molecular Evolution. Sunderland, MA: Sinauer
Associates.
Hannenhalli, S., and Levy, S. 2001. Promoter prediction in the human genome. Bioinformatics 17
(Suppl):S90-6.
Hehl, R., and Wingender, E. 2001.Database-assisted promoter analysis. Trends Plant Sci. 6:251–5.
Higgins, D. G. 2000. Amino acid-based phylogeny and alignment. Adv. Protein Chem. 54:99–135.
Hughes, A. E. 2001. Sequence databases and the Internet. Methods Mol. Biol. 167:215–23.
Karlin, S., and Altschul, S. F. 1993. Applications and statistics for multiple high-scoring segments in
molecular sequences. Proc. Natl. Acad. Sci. U S A 90:5873–7.
Mullan, L. J., and Williams, G. W. 2002. BLAST and go? Brief. Bioinform. 3:200–2.
Nei, M., and Kumar, S. 2000. Molecular Evolution and Phylogenetics. New York: Oxford University
Press.
Nunes de Castro L., Von Zuben F. J. 2005. Recent Developments in Biologically Inspired Computing.
Idea Group Publishing.
Ohler, U., and Niemann, H. 2001. Identification and analysis of eukaryotic promoters: Recent
computational approaches. Trends Genet. 17:56–60.
Ovcharenko, I., and Loots, G. G. 2003. Finding the needle in the haystack: Computational strategies
for discovering regulatory sequences in genomes. Curr. Genomics 4: 557– 568.
Patnaik, S. K., and Blumenfeld, O. O. 2001. Use of on-line tools and databases for routine sequence
analyses. Anal. Biochem. 289:1–9.
Qiu, P. 2003. Recent advances in computational promoter analysis in understanding the
transcriptional regulatory network. Biochem. Biophys. Res. Commun. 309:495–501.
Rombauts S., Florquin K., Lescot M., Marchal K., Rouze P., and van de Peer Y. 2003. Computational
approaches to identify promoters and cis-regulatory elements in plant genomes. Plant Physiol.
132:1162-76.
Salemi, M., and Vandamme, A. M. 2003. The Phylogenetics Handbook – A Practical Approach to DNA
and Protein Phylogeny. Cambridge, UK: Cambridge University Press.
Sansom, C. 2000. Database searching with DNA and protein sequences: An introduction. Brief.
Spang, R., and Vingron, M. 1998. Statistics of large-scale sequence searching. Bioinformatics 14:279–
84.
Stein, L. D. 2003. Integrating biological databases. Nat. Rev. Genet. 4:337–45.
67
Structural Bioinformatics. 2003. Edited by Philip E. Bourne and Helge Weissig. John Wiley & Sons,
Inc.
Thornton, J. W., and DeSalle, R. 2000. Gene family evolution and homology: Genomics meets
phylogenetics. Annu. Rev. Genomics Hum. Genet. 1:41–73.
Whelan, S., Lio, P., and Goldman, N. 2001. Molecular phylogenetics: State of the art methods for
looking into the past. Trends Genet. 17:262–72.
Xiong, J., 2006. Essential Bioinformatics. Publish in the United States of America by Cambridge
University Press, New York.
Teaching methods: Debates, case study, modelling – brainstorming.
Course’s name: Microbial Biotechnologies for Used Waters
CREDITS ECTS: 8
Semester III
Course’s holder: Reader Professor PhD Simona Isabela DUNCA
Objectives: Assimilation of thorough knowledge about wastewater.
Knowledge of the wastewater microbiota, biological filters and biofilms.
Presentation of the wastewater treatment technologies.
Formation of an eco-friendly conception on the self-purification of polluted waters.
Consolidation and broadening of the knowledge acquired during classes or laboratory courses by
solving theoretical and practical problems.
Genetics.
General topic:
Classification of wastewater: Municipal wastewater; Industrial wastewater; Wastewater from animal
husbandry.
Wastewater microbiota
Technologies for wastewater treatment - Biological treatment: Aerobic treatment technologies:
Biological filters: microbiota of the biological filters; biofilm architecture; mechanism of the microbial
activity in biofilters; biofilter efficiency; Activated sludge: structure and formation of the activated sludge
flocs; microbiota of the activated sludge basins (i.e. bacteria, fungi, algae, protozoa); swelling of
activated sludge; causes for swelling and involved microbiota; Anaerobic treatment technologies:
Populations of microorganisms; Non-methanogen and methanogen microbiota; Evolution of the
process of waste anaerobic degradation; Anaerobic ponds; Stabilization or oxidation biological ponds.
Microorganisms as indicators of pollution - Bacteriological criteria for assessing treated wastewater.
Wastewater self-purification - Changes caused by wastewater disposal; Self-purification.
Bacterial nitrification and denitrification as biological methods to remove nitrogen compounds from
wastewater.
Seminar’s topic:
Wastewater microbiota - Calculation of the number of bacteria growing at 370 C (mesophilic bacteria);
Calculation of the number of actinomycetes and fungi.
Ecophysiological groups of micro-organisms present in the activated sludge which carry out the
purification process - Identification of the micro-organisms responsible for ammonification, nitrification
and denitrification; Identification of the aerobic and anaerobic cellulosolytic micro-organisms;
Identification of the proteolytic micro-organisms; Identification of the sulphur-oxidising and sulphatereducing micro-organisms.
Bacteriological criteria for assessing treated wastewater (effluent) - Determination of total coliform
bacteria, fecal coliform bacteria, E. coli assay; Determination of fecal streptococci.
Purification of wastewater using activated sludge - Description of the activated sludge in the oxidation
basins: Microscopic examination of the activated sludge (sludge structure); Determination of moisture
content and dry matter; Determination of the SVI (sludge volume index); Determination of the aerobic
and anaerobic microbiota in order to calculate the aerobic/anaerobic ratio as an indicator of the
effectiveness of the purification process;
Presentation of the municipal wastewater treatment plant S.C. “APAVITAL” S.A. IAŞI.
References
68
Ailiesei Octavita, Erica Nimitan, Comanescu, St., 1980 – Lucrari practice de microbiologie generala,
Ed.Universitatii “Al.I.Cuza” Iasi.
Dunca Simona, Octavita Ailiesei, Erica Nimitan, Stefan Marius, 2004 - Microbiologie aplicata Ed.Tehnopress, Iasi, 293 pg.
Dunca Simona, Octavita Ailiesei, Erica Nimitan, Stefan Marius, 2005 - Elemente de microbiologie,
vol.1 - Ed. Junimea, Iasi, 263 pg.
Glazer, N.A., Nicaido, H.,1995 – Microbial Biotechnology, W.H.Freeman and Company, U.S.A.
Munster U., Chrost R.J., 1990 – Origin, composition and microbial utilization of dissolved organic
matter. In: Overbeck J. si Chrost R.J. (Eds.): Aquatic microbial ecology. Brock/Springer Ser. Contemp.
Biosci., New York, p. 8-46.
Rosenberg, E., 1993 – Microorganism to combat poluttion, Kluwer Academic Publishers, Nehterlands.
Wistreich, G. A., 1997 – Microbiology Laboratory, Prentice Hall, Upper Saddle River, New Jersey.
Zarnea, G., 1994 – Tratat de microbiologie generala, vol. V, Ed. Academiei Romane, Bucuresti.
experiment, observation.
Course’s name: Food Biochemistry
CREDITS ECTS: 8
Semester III
Course’s holder: Lecturer PhD Lacramioara OPRICA
Objectives: Summarizing the basic constituents of food (carbohydrates, lipids, proteins, pigments,
vitamins, aromatic substances) with reference to their composition and nutritional value;
Exposure of the main classes of food and their biochemical features;
Description of biochemical phenomena and processes explanation taking place in food production and
technology transformation (processing, preservation, storage) of them, too.
Recommended/obligatory courses: General chemistry, Biochemistry, Structural biochemistry,
Biochemical transformation of carbohydrates and lipids, Metabolism of proteins and nucleic acid.
General topic:
General on food composition
Simple carbohydrates and derived products (pentose, hexose, atypical ose, polyols, sucrose, lactose,
heteroside);
Glycans (starch, inulin, cellulose, gum, pectins);
Fat (saturated and unsaturated fatty acids, acylglycerols, phospholipids, ceride);
Proteins (amino acids, primary structure, secondary, tertiary and quaternary, the relationship of water
and proteins; non-enzymatic browning, Maillard reaction);
Mineral (macroelements - Na, K, Ca, P, Mg, trace elements - Fe, Cu, Zn, Se, I and biological activity);
Water (water properties in food, water activity and changes in food);
Vitamins (use and stability of vitamins);
Pigments (chlorophylls, flavonoids and other food compounds);
Biochemistry of cereals, flours and bakery products (chemical composition of grain)
Fermented beverages (general on the fermentation, the wine and beer)
Biochemistry of milk and milk products (lactose and oligosaccharides, milk lipids and proteins
classification, general regarding cheese and other dairy products obtain)
Biochemistry of meat and eggs
Biochemistry of vegetables and fruit
Food additives
Seminar’s topic:
Determination of water foods content;
Determination of milk, beverages (beer, wine, juice), bread acidity;
Determination of food sodium chloride content (cheese, cottage cheese)
Determination of total lipids from seeds cereals;
Determining the origin of the honey and forgeries detection
Determination of fat peroxide index (butter, poultry fat)
Determination of milk and other fruits proteins;
69
Determination of meat sanitation (peroxidase identification, Eber reaction, Nessler reaction, hydrogen
sulfide identification);
Determination of vitamin A in egg yolk (Carr & Price method);
Determination of vitamin C in fruit;
Determination of β-carotene in fruits and vegetables.
References
Alais Charles, Guy Linden, Laurent Miclo Dunod, Biochimie alimentaire, Edit. Science Sup., 2004.
Artenie V., Ungureanu Eugen, Negura Anca, Metode de investigare a metabolismului glucidic si lipidic,
Edit. Pim, 2008
Huy Y.H., Food biochemistry and food processing, Blackwell Publishing, 2006.
Cojocaru D. C., Biochimia vitaminelor, Ed. Gama, Iasi, 1996.
Cojocaru D. C., Enzimologie, Ed. Gama, Iasi, 1997.
Cojocaru D.C., Ciornea Elena, Doina-Irina Cojocaru, Biochimia vitaminelor si hormonilor - lucrari
practice, Editura Corson, Iasi, 2000
Cojocaru, D. C. Enzimologie practica, Ed. Tehnopress, Iasi, 2005.
Dumitrescu Horia, Constantin Milu, Controlul fizico-chimic al alimentelor, Editura medicala, Bucuresti,
1997
Moraru C., Biochimia produselor alimenare, Edit. Tehnica, Bucuresti, 1972.
Hames B.D. &Hooper N.M., Biochemistry-second edition, Bios Scientific Publishers Ltd., 2005.
Hans-Walter Heldt, Plant biochemistry, third edition, Elsevier Academic Press, 2005.
Neamtu Gavril, Biochimia alimentara, Editura Ceres, 1997.
Neamtu Gavril, Biochimia alimentara, Editura Ceres, 1997.
Negut Elena, Biochimia alimentelor, Edit. Bioterra, Bucuresti, 2000.
Teaching methods: Lectures, modelling, debates, video-projection, experiment, case study, euristic
conversation.
Course’s name: Enzymatic biotechnologies
CREDITS ECTS: 7
Semester III
Course’s holder: Professor PhD Dumitru COJOCARU
Objectives: Advanced knowledge regarding extraction methods of enzyme from different sources
Enzyme immobilization, organites and whole cell
Practical usage of enzyme and immobilized enzymes.
Recommended/obligatory courses: Enzymology; Biochemistry; Microbiology; Biotechnology.
General topic:
Industrial usable enzyme sources – Animal enzymes; Plant enzymes; Microbial enzymes
Obtaining industrial applicable enzymes – Choosing the right source of enzymes; Enzymes
extractions; Enzyme purification methods; Purity check; Methods for enzyme immobilization on solid
supports
Utilization on enzymes in industry – Milk and dairy industry; Alcoholic drinks industry; Meat and meat
products industry; Waste waters treatments
Enzymes with medical applications
Enzymes with biotechnological applications.
Seminar’s topic:
Separation and purification on plant catalase
Separation and purification of yeast invertase
Separation and purification of yeast alcohol dehidrogenase
Obtaining inverted sugar
Catalase imobilization on poliacrilamide gels
Invertase immobilization on cellulose fibres using glutaric aldehide
Including Saccharomyces cerevisiae cells in agar gels.
References
70
Cojocaru, D. C. – 2005, Enzimologie aplicata, Ed. TEHNOPRESS, Iasi
Dumitru, I. F. - 1981, Biochimie, Ed. Did. si Ped. Bucuresti
Pelmont, Y. – 1992, Enzymes, Presses Universitaires de Grenoble
Course’s name: Animal Cell Cultures in Biotechnology
CREDITS ECTS: 7
Semester III
Course’s holder: Lecturer PhD Cristian CIMPEANU
Acquiring proficiency on DNA technologies methods.
General topic:
From donor to cell lines
Normal cell and transformed cell lines
In vitro culture of animal cells
Cell lines authentification
Animal cell culture contamination
Animal cell cultures in biotechnology
Seminar’s topic:
Primary cell culture
Animal cell culture maintenance
Cell lines
Cell viability
Cryopreservation
Organs cultures
Mouse embryonic cell cultures
Specialized cell cultures
References
Freshney, R.I. Animal Cell Culture: A Practical Approach. 1986. IRL Press, Oxford.
Jakoby, W.B. and Pastan, I.H. Cell Culture: Methods in Enzymology, Vol 58. 1988. Academic Press,
San Diego.
Baserga, R. Ed. Cell Growth and Division: A Practical Approach. 1989. IRL Press, Oxford.
Cormier, F. and Dieterlen, F. Long-term cultures of chicken bone marrow cells. Lievre, 1990. Exp. Cell
Research 190: 113-117
Ausubel FM, Brent R, Kingston RE et al. (eds). 1999. Short Protocols in Molecular Biology, 4th edn.
New York: Wiley.
Brown TA (1999) Genomes. New York: Wiley-Liss.
Spector DL, Goldman RD, Leinwand LA (eds). 1998. Cells: A Laboratory Manual. Cold Spring Harbor,
NY: Cold Spring Harbor Laboratory Press.
Watson JD, Gilman M, Witkowski J & Zoller M. 1992. Recombinant DNA, 2nd edn. New York: WH
Freeman.
Freshney RI. 2000. Culture of Animal Cells: A Manual of Basic Technique, 4th edn. New York: Wiley
Teaching methods: Exposure, demonstration, conversation, case studies
Course’s name: Gene manipulation in biotechnologies
CREDITS ECTS: 6
Semester IV
Objectives: Identify and analyze the main domains/components of Biotechnology
71
Describe the laws and phenomena of genetic information transmission and modification
Knowledge of the most important technologies for genetic information manipulation and its main
applications.
Demonstrate a minimum level of practical knowledge of recombinant DNA technology and genome
modification in micro-organisms, plants and animals.
Recommended/obligatory courses: Biochemistry, Cellular Biology, General Genetics, Microbiology.
General topic:
Introduction
Conventional biotechnologies and the emergence of modern biotechnologies
Basic techniques in molecular biology
Recombinant DNA technology: DNA molecules manipulation, plasmides and cloning vectors,
bacteriophages and cosmids, cloning strategies ang gene libraries, recombinants selection and
screening,
Cloning in bacteria, unicellular eukaryotes and superior organisms
General methodology of plant genome manipulation
General methodology of animal genome manipulation
General methodology of human genome manipulation
Gene therapy
Seminar’s topic:
Biological system used in biotechnologies
Unicellular systems for foreign gene expression
Pluricellular systems for foreign gene expression
Applications: Molecular diagnosis, therapeutic compounds obtained by micro-organisms
biotechnologies, vaccine, plant amelioration, microbian insecticides, genetic modified organisms in
agriculture, transgenic animals, cloning, gene therapy
References
Bara I, Cimpeanu Mirela, 2003 – Genetica, Ed. Corson, Iasi
Castle D., Ries N. , 2009 – Nutrition and Genomics, Elsevier, NY
Castilho R.L., Moraes A.M., Augusto E., Butler M., 2008 – Animal cell technology-from
biopharmaceuticals to gene therapy, Taylor and Francis, New York.
Kalow W., Meyer U., Tyndale R. 2005 – Pharmacogenomics, Taylor and Francis, NY
Lucio G.C., Eaton D., 2006 – Fundamentals of Ecogenetics, Gene-Environment Interactions, John
Wiley & Sons, Inc
Patras Xenia, Tudose C., 2003 – Farmacogenetica, Ed. Tehnopres, Iasi.
Vantu, S. 2005 - Culturi de celule si tesuturi vegetale in biotehnologie, Ed. Univ. „Al. I. Cuza”, Iasi
Vinci V., Parekh S., 2003 – Handbook of industrial cell culture – mammalian, microbial and plant cells,
Humana Press, New Jersey.
Teaching methods: Lectures, euristic conversation, debates, case study, experiment, modelling –
brainstorming
Course’s name: Biotechnologies Used in Immunology
CREDITS ECTS: 6
Semester IV
Course’s holder: Lecturer PhD Marius STEFAN
Objectives: Looking into immune system knowledge.
Knowing the theoretical basis of monoclonal antibodies producing techniques.
Acquiring new information about monoclonal antibodies practical applications
Presentation of vaccine preparation biotechnologies.
Recommended/obligatory courses: General Chemistry, Biochemistry, General
Imunobiology.
General topic:
Introduction
Overview of the immune system
72
Microbiology,
Hibridoma technology - Fusion of the somatic cells; Obtaining of myeloma cells; Molecular basis of
selection process; Advantages of hibridoma technology
Theoretical basis of monoclonal antibodies technology
Production of monoclonal antibodies
Practical application of monoclonal antibodies (mAb) - Study of cell membrane molecules; Utilisation
of mAb as in vivo and in vitro diagnostic reagents; Utilisation of mAb in therapy; Monoclonal antibodies
as scientific tools; Utilisation of mAb in biotechnology; Immunotoxins; Antibody − Drug Conjugates;
Immunoliposomes
Vaccines obtained using modern biotechnologies.
Seminar’s topic:
Obtaining of immune serum
Evaluation of fagocites role in fagocytosis
Identification methods of different lymphocytes types
Immunodiffusion
Simple diffusion
Double diffusion
Immunoelectrophoresis
Immunoprecipitation
Uhlenhaut reaction
Utilisation of immunoprecipitation in food control
Immunofluorescence
Latex agglutination
Immuno-enzymatic test (ELISA)
Antibodies identification
References
Abbas, A. K., Lichtman, A.H., 2007 - Basic Immunology: Functions and Disorders of the Immune
System, W B Saunders Co. Ed.
Burmester, G.R., Pezzutto, A., 2003 - Color atlas of immunology, Thieme Berlin Ed.
De Frank C. Hay, Olwyn M. R. Westwood, Paul N. Nelson, Leslie Hudson, 2002 - Practical
Immunology, Blackwell Publishing.
Eales, L., 2003 - Immunology for Life Scientists, Ed. John Wiley & Sons.
Goers, J., 1993 - Immunochemical Techniques. Laboratory Manual. Acad. Press, New York.
Hayand, F.H., Olwyn M.R., 2002 - Practical Immunology, Westwood Blackwell Science Oxford UK.
Kindt, T.J., Osborne, B.A., Goldsby, R.A., Kuby, J., 2006 - Kuby Immunology, W H Freeman & Co. Ed.
Nijkamp, F.P., Parnham, M.J., 2005 - Principles of Immunopharmacology, Birkhäuser Verlag, Berlin.
Paul, W.E., 2003 - Fundamental Immunology, 5th edition, Lippincott Williams & Wilkins Publishers.
Roitt, I., Brostoff, J., Male, D., 2007 - Immunology, 5 th Edition, Mosby Ed.
experiment, observation
Course’s name: Microbial Bioconversions
CREDITS ECTS: 6
Semester IV
Objectives: Presentation of the impact of micro-organisms on the conversion of scrap materials,
agricultural or industrial by-products.
Further and thorough learning about the capitalization of classic microbial biotechnologies using
methods of genetic engineering
Learning about the conversion mechanisms and micro-organisms mediating such processes.
Consolidation and broadening of the knowledge acquired during classes or laboratory courses by
solving theoretical and practical problems.
Genetics.
General topic:
73
Conversion of scrap materials, agricultural and industrial by-products using micro-organisms - Nature
and quantities of by-products and scrap materials; Degradation and conversion by micro-organisms;
Using micro-organisms in the fight against pollution.
Production of energy using micro-organisms - Biomass and energy; Production of alcohol fuels;
Production of biogas; Production of hydrocarbons using Botryococcus braunii.
Photo-production of hydrogen and conversion of light energy.
Bacterial methanogenesis – Generalities; Morphology and structure of methanogen bacteria;
Physiology of methanogen bacteria; Carbon cycle in methanogen habitats.
Biotechnological reclaiming of the whey resulted from cheese product manufacturing in order to obtain
yeast biomass.
Seminar’s topic:
Highlighting the process of bacterial methanogenesis using activated sludge from the Iasi wastewater
treatment plant.
Anaerobic biodegradation of Amberlite resins.
Manufacturing process of fodder yeast using, as substrate, spent sulphite liquors and prehydrolysed
materials from cellulose product manufacturing.
Biotechnological reclaiming of the whey resulted from cheese product manufacturing in order to obtain
yeast biomass - Isolation of yeasts capable to bioconverse lactose from natural sources and
identification of strains producing yeast biomass; Determining the optimal content of lactose in the
whey; Addition of nutritive substances to the whey: emphasizing the action of organic nitrogen
compounds: urea and peptone; influence of the phosphorus source: mono and bibasic phosphates;
influence of the growth factors contained by the yeast extract; Optimization of the growth conditions of
the isolated yeasts in order to increase biomass; Dynamics of the laboratory fermentation parameters.
References
Anghel, I., 1993- Biologia si tehnologia drojdiilor - vol.III, Ed. Tehnica, Bucuresti.
Costin, Gh.M, Lungulescu, Gr., 1985- Valorificarea subproduselor din industria laptelui - Ed. Tehnica,
Bucuresti.
Johnson, T.R., Case, C.L., 1998 – Laboratory experiments in microbiology – The Benjamin Cummings
Publishing Company, Inc.
Nimitan, Erica, Octavita, Ailiesei, Simona, Dunca, Comanescu, St., 1998 – Metode si tehnici de
microbiologie - Ed. Universitatii “Al.I.Cuza “ Iasi.
Madigan,M., Martinko,J., Parker,J., 2000 – Brock Biology of microorganisms, 8th edition- Prentice
Hall., Inc.Simon & Schuster, Viacom Company, New Jersey.
Manoliu, Al., Elena Marin, Comanescu, St., 1998 – Noutati in Microbiologie si Biotehnologie. Lucrarile
celui de al IX-lea Simpozion de Microbiologie si Biotehnologie- Ed. Corson, Iasi.
Rose, A.M., 1981 – Microbial biodeterioration - Academic Press, New York.
Wistreich, G. A., 1997 – Microbiology Laboratory - Prentice Hall, Upper Saddle River, New Jersey.
Zarnea, G., 1984 – Tratat de microbiologie generala - vol. II, Ed. Academiei R.S.R., Bucuresti.
Zarnea, G., 1994 – Tratat de microbiologie generala - vol. V, Ed. Academiei Romane, Bucuresti.
Course’s name: Biochemistry of Microorganism Metabolites
CREDITS ECTS: 6
Semester IV
Course’s holder: Lecturer PhD Lacramioara OPRICA
Objectives: Presentation of some aspects regarding the microbial metabolism and the importance of
industrial
micro-organisms
producing
biologically
active
substances.
Examples and explain of producing microbial primary metabolites biochemical pathways.
Examples and explain of producing microbial secondary metabolites biochemical pathways..
Recommended/obligatory courses: General chemistry, Biochemistry, Structural biochemistry,
Microbiology.
General topic:
Characterization of some biotechnological interest microorganisms (bacteria, yeast, fungi)
74
General terms of microbial metabolism - Degradation pathway of the substrate; Biosynthesis pathway
of cell constituents; Biological significance of primary and secondary metabolites; The relationship
between primary and secondary metabolism
Primary microbial metabolites - Products obtained from fermentation: alcoholic fermentation, lactic
fermentation, (propionic, butyric, acetic, citric, gluconic, itaconic, etc.) acids fermentation; Microbial
biosynthesis of amino acids (lysine, tryptophan, phenylalanine, L-glutamic acid); Microbial
biosynthesis of vitamins (riboflavin, pyridoxine, etc.); Microbial biosynthesis enzymes (amylase,
cellulase, protease, lipase etc);
Secondary microbial metabolites - Microbial mycotoxins (Aflatoxins, Ochratoxin, Trichothecene,
zearalenone, Fumonisins, Patulin, Citrinin, Sterigmatocistin, Moniliformin, Gliotoxine); Microbial
alkaloids (classification, structure and organic matter); Antibiotics: general concepts, classification (βlactam antibiotics, griseofulvin, aminoglycoside antibiotics, tetracycline), other classes and types of
antibiotics.
References
Carlile M. J., Watkinson Sarah - The fungi, Academic Press, London, Boston, San Diego, New York,
Sydney, Tokyo, 1994.
Cojocaru D. C. - Enzimologie, Ed. Gama, Iasi, 1997.
Kavanagh Kevin - Fungi, Biology and Applications, John Wiley & Sons, Ltd., 2005.
Jurcoane Elena - Tratat de Biotehnologie, vol. I, Editura Tehnica, Bucuresti, 2004.
Hanson James R. - The Chemistry of Fungi, Published by The Royal Society of Chemistry,
Thomas Graham House, Science Park, Milton Road, Cambridge CB4 0WF, UK, 2008.
Richard Cole, Milbra Schweikert, Handbook of secondary metabolites, fungal metabolites, Academic
press, 2003.
Rezessy-Szabo Judit, Anna Maraz, Microbial Biotechnology, Budapest, 2006.
Surdu Stefania, Zenovia Olteanu, Elena Truta - Genul Claviceps - biologie si biotehnologie - vol I, Edit.
Cermi, 2005.
Zarnea G. - Tratat de Microbiologie generala, vol. II, Edit. Academiei Romane, 1984.
¾ BIO-PROCEEDINGS IN AGRO-ALIMENTARY INDUSTRIES
This master degree studies programme began in 2000 and represents a result of the
remarkable cooperation between the „Al. I. Cuza” University Iasi (through the Biochemistry
and Molecular Biology Laboratory from the Faculty of Biology) and the University of Sciences
and Technologies Lille-1 from France (through the department coordinated by Professor PhD
Didier Guillochon). Through the cooperation agreement, the personal from these two
departments are doing commonly didactic and scientific programmes, while the students and
professors are doing mutual visits in these laboratories.
In the proximate future, we want to develop an European master degree program
starting from the present programme, the Romanian students being students in the similar
programme from the University of Sciences and Technologies Lille-1, receiving a double
diplomas starting from the stages and transferable credits obtained in the French university.
The curriculum of this programme follows to increase the practical applicability of the
theoretically knowledge and to prepare the graduates for the molecular and cells’ researches
in the alimentary industry biotechnologies’ topic, regarding the vegetal products’ quality,
technology interest molecules’ obtaining, development of new proceedings in the aliments’
quality and security’s improvement.
The dissertation paper’s topic represents one study of great applicability in the
alimentary industries topic.
The master degree programme assures the graduates’ formation in the following
alimentary and molecular biology biotechnologies domains:
• a good knowledge of the actual biotechnologies in alimentary industry;
75
• implementation of the new biotechnologies in the alimentary industries in order to obtain
ecological products;
• knowledge of the actual successes in the practical domains of the alimentary industry like
the fermentative processes’ biotechnology, alimentary toxicology, alimentary microbiology,
alimentary chemistry, enzymatic engineering, etc.
The existing material basis allows modern studies of enzymatic engineering with
practical applicability in the alimentary industry and other domains of the human activity
medicine, the control of the products’ quality, antibiotic industry, scientific research, etc. The
students can participate in the research programmes on-going in the Biochemistry and
Molecular Biology Laboratory.
all domains of alimentary industry;
products’ quality’s control laboratories;
phyto-sanitary and Agro-forestry control laboratories;
antibiotics industry;
research laboratories from universities;
higher education institutions teaching biology, medicine, agronomy etc.;
diagnostic laboratories;
molecular biology research institutes.
76
Faculty of Biology
APROVED
Valid for :
1st Year: 2009 - 2010
2nd Year: 2010 - 2011
PROGRAMMES OF STUDY
Specialisation: Master degree – Bio-proceedings in agro-alimentary industries
No.
Name of the subject
C
S
L
Credits
Pr
Evaluation type
Colloquium
Exam
1
Basic Biotechnologies Used In Fermentative Processes
2
0
1
6
I
2
"In Vitro" Genetic Manipulation of the Vegetal Cells
1
0
1
6
I
3
Feeding Toxicology
2
0
2
6
I
4
Transgenic Organisms
1
0
1
6
I
5
Biostatistics
1
2
0
6
I
7
2
5
30
TOTAL
nd
2
ST
SEMESTER (1
0
5
YEAR)
1
Enzimatic Engineering
2
0
2
6
II
2
Food Microbiology
2
0
1
6
II
3
Food Chemistry
1
0
1
6
II
4
Informatics and Biological Systems Modelling
1
2
0
6
II
5
Genomics
1
0
1
6
II
7
2
5
30
TOTAL
rd
nd
3 SEMESTER (2
YEAR)
0
5
1
Proteom
1
0
1
6
III
2
Biochemical Transformations Involved in Food Preservation
1
0
2
6
III
3
Biochemistry of Nutrition
1
1
0
6
III
4
Industrial Enzymes
2
0
2
6
III
5
Selected Microrganisms for Food Industry
2
0
1
6
III
7
1
6
30
2
0
1
8
IV
TOTAL
th
nd
4 SEMESTER (2
1
0
5
YEAR)
Methabolic Pathways in Agro-Alimentary Materials
2
0
1
8
IV
3
Microbiology of Foods and the Breguency of Contaminant
Microorganisms
Computer Modelling of Biochemical Process
2
0
0
7
IV
4
Magnum practicum
0
0
6
7
IV
5
(facultative)
0
0
90
5*
IV
TOTAL
6
0
8
30
2
No.
1
2
0
5
No. of classes
Examination
Sem.
Credits
type
C
A
levels)
1
2
28
28
14
14
5
5
Exam
Exam
3
28
14
5
Exam
4
4
0
42
5
Colloquium
5
2
14
28
5
Exam
3
78
6
3
1
2
3
4
4
14
28
5
Exam
30
5E+1C
5
Exam
IMPORTANT NOTES:
The master’s degree in Biology, specialization BIO-PROCEEDINGS IN AGRO-ALIMENTARY INDUSTRIES can be conferred only to students
that have obtained 120 credits in the obligatory disciplines from the hereof syllabus.
79
Course’s name: Basic Biotechnologies Used In Fermentative Processes
CREDITS ECTS: 6
Semester I
Objectives: Performing biotechnological methods in fermentative processes;
Modern techniques of biotechnological investigations and apparatus.
Recommended/obligatory courses: General chemistry, Structural biochemistry, Analytical
biochemistry.
General topic:
Nature and variety of biotechnological processes
Fermentations
Biotechnological processes
Seminar’s topic:
Fermentative and biotechnological processes
Distillation
Fermentation
Conditionation
Depectinization
Conservation
Dietetization
References
Berzescu P., Kathrein I., Dumitrescu M., Hopulele T., Stoicescu M., 1981 – Tehnologia berii si a
maltului, Ed. Ceres, Bucuresti
Cotea V., 1985 - Oenologie, Ed. Ceres, Bucuresti
Chintescu G., Grigore G., 1985 - Indrumator pentru industria produselor lactate, Ed. Tehnica,
Bucuresti
Mencinicopschi Gh., Kathrein I., Teodoru V., 1987 – Biotehnologii in
prelucrarea produselor
alimentare, Ed. Ceres, Bucuresti
Moldoveanu G., 1977 – Tehnologia panificatiei, Ed. Didactica si Pedagogica, Bucuresti
Pavel O., 1983 – Tehnologia prelucrarii carnii, Ed. Didactica si Pedagogica, Bucuresti
Sasson A. , 1988 – Les biotechnologies: defis et promesses, Imprimerie des Presses Universitaires de
France, Vendome
Scriban Rene, 1993 - Biotechnologie, 4-eme Edition, Technique & Documentation – Lavoisier, Paris
Toma O., Pirianu G., 2001 – Biotehnologie : metode & procesare, Ed. Arc 2000, Bucuresti
Toma O., 2008 – Metode si procesare in biotehnologie. Casa Editoriala Demiurg, Iasi
Zarnea G., Mencinicopschi G., Bragarea S., 1980 – Bioingineria preparatelor enzimatice microbiene,
Ed. Tehnica, Bucuresti
Course’s name: "In Vitro" Genetic Manipulation of the Vegetal Cells
CREDITS ECTS: 6
Semester I
The comparative study of ontogenesis “in vivo” and “in “in vitro”
methods.
General topic:
“In vitro” genetic manipulation - Definition and short history; Plant cell – “In vitro” methods of cell
cultures; The protoplasts- model systems of genetic engineering; Somatic hybridization; Molecular
hybridization; The methods of transgenic plants obtainment; The applications in medicine, agriculture
and industry.
Seminar’s topic:
The methods of protoplasts isolation and cultivation
The somatic hybridisation
The cybridisation
The methods of nucleus, organelles and chromosomes transfer to protoplasts
The direct methods of transgenesis
The indirect methods of transgenesis.
References
Bhojwani S., Razdan M. K., 1996 – Plant Tissue Culture :Theory and Practice, In: Developments in
Chrispeels, M.J., Sadava, D.E., 2003 - Plants, Genes and Crop Biotechnology, Jones and Bartlett
Publishers
Giardi, M.T., Piletska, E. 2006 - Biotechnological Applications of Photosynthetic Proteins
Kan Wang, 2006 - Agrobacterium Protocols, vol I, II
Lorz,H.; Wenzel, G. 2005-Molecular Marker Systems in Plant Breeding and Crop Improvement
Rai, Ashwani K; Takabe, Teruhiro 2006- Abiotic Stress Tolerance in Plants
Verma, Desh Pal S.; Hong, Zonglie 2008- Cell Division Control in Plants.
Teaching methods: Lectures, modelling – brainstorming
Course’s name: Feeding Toxicology
CREDITS ECTS: 6
Semester I
Course’s holder: Reader Professor PhD Anca Mihaela NEGURA
Objectives: Knowing the toxic substances: origin, physical, chemical and biological properties,
dosage/answer relationship
Knowledge about the effects of food toxic compounds on living organisms.
Recommended/obligatory courses: Toxicology, Structural biochemistry, Carbohydrates and lipids
metabolism, Proteins and nucleic acids metabolism, General chemistry.
General topic:
Introduction – Food toxicology: definition, aim and study methods.
Natural toxins present in vegetal food: cyanogenetic glycosides, lectins, digestive enzymes inhibitors,
active amines, phytoestrogens, saponines.
Natural toxins present in animal foods: toxins from animal liver, toxins from marine organisms.
Natural contaminants of food: mycotoxins.
Industrial contaminants in food: heavy metals, nitrates and nitrites, pesticides, polychlorbiphenyls,
dioxins.
Food additives: antioxidants, sweeteners, colorants, preservatives, emulsifiers.
Toxic compounds generated during food processing: polycyclic aromatic hydrocarbons, Maillard
reaction products, nitrosamines
Seminar’s topic:
Determination and identification of toxic compounds from food.
References
Ayres, J. C., and Kirschman, J. C. (eds.) 1981, “Impact of Toxicology on Food Processing.” AVI
Publishing Co., Westport Connecticut.
Graham, H. (ed.) 1998, ‘The Safety of Foods,” 2nd Ed. AVI Publishing Company. Westport,
Connecticut.
Hathcock, J. N. (ed.) 1982—1989, “Nutritional Toxicology.” Academic Press, New York.
Lewis, R. J., Sr., 1989, “Food Additives Handbook.” Van Nostrand Reinhold, New York.
Miller, K. (ed.) 1987, “Toxicological Aspects of Food.” Elsevier Applied Science, New York.
Millstone, E., 1986, “Food Additives.” Penguin Books, New York.
81
Ory, R. L. (ed.) 1981, “Antinutrients and Natural Toxicants in Foods.” Food & Nutrition Press,
Westport, Connecticut.
Watson, D. H. (ed.) 1987, “Natural Toxicants in Food: Progress and Prospects.” VCH Publishers, New
York.
Teaching methods: Lectures, euristic conversation, modelling – brainstorming, experiment,
observation.
Course’s name: Transgenic Organisms
CREDITS ECTS: 6
Semester I
General topic:
Animal cell culture
Cloning
Genic therapy
Seminar’s topic:
Vaccines
Pharming
Therapeutically cloning
References
USA
Course’s name: Biostatistics
CREDITS ECTS: 6
Semester I
General topic:
82
Testing statistical hypotheses and scientific methodology: Testing hypothesis concerning the mean of
a single population (t (Student) test for one sample); statistical decision-making.
Comparison of 2 independent samples: t (Student) test for independent observations; Mann-Whitney
test.
Seminar’s topic:
Testing hypothesis concerning the mean of a single population: t (Student) test for one sample –
exercises.
References
Bailey, T.J.N. (1981): Statistical Methods in Biology. Editia a II-a. Ed. Cambridge University Press.
Longman.
Publishers.
Iosifescu M., Moineagu C., Trebici V.,Ursianu E. (1985): Mica enciclopedie de statistica. Ed. Știintifica
si Enciclopedica, Bucuresti
Snedecor, W.G. (1968): Metode statistice aplicate in cercetarile de agricultura si biologie (traducere
din limba engleza). Bucuresti.
Zamfirescu, S.R., Zamfirescu, O. (2008) Elemente de statistica aplicate in Ecologie. Ed. Univ. „Al.I.
Cuza” Iasi.
Teaching methods: Lectures, euristic conversation, demonstration, practical application
Course’s name: Enzimatic Engineering
CREDITS ECTS: 6
Semester II
Course’s holder: Professor PhD Didier GUILLOCHON, Sciences and Technologies Universiy Lille IUT, France
General topic:
83
Immobilization of enzymes - immobilization methods; introduction in enzymatic heterogeneous
catalysis: partage phenomenon; transfer phenomenon; main types of enzymatic reactions
Non-aqueous Enzymology - general principles; enzyme activity in organic environments; stability of
enzymes in organic solvents; specificity of enzymes in organic environments; application of enzymes
in Non-aqueous environments; enzymatic engineering in organic environments
Industrial application of enzymes - food industry; other industrial applications
Immobilization supports - electrochemical supports; optic supports; semi-conductive supports;
piezoelectric-electric supports; enthalpy supports
References
Génie enzymatiques, G. Coutouly, Ed. Masson-doin
Biotechnologies: Principes et Méthodes, M. Larpent-Gourgaud, J. J. Sanglier, Ed. Biosciences et
Techniques-doin
Methods in non-Aqueous Enzymology, Munishwar Nath
Methods and Tools in Biosciences and Medicine, Gupta
Biochimie Agro-alimentaire, G. Linden, D. Lorent, Ed. Masson
Teaching methods: Lectures, debates, modelling – brainstorming, experiment
Teaching language: French
Course’s name: Food Microbiology
CREDITS ECTS: 6
Semester II
Course’s holder: Reader Professor PhD François KRIER, IUT „A” Sciences and Technologies
University Lille, France
General topic:
General introduction to Food Microbiology
Morphologic characterization of micro-organisms
Microbial metabolism
Microbiological analysis of food - Microbiological criteria; strains used in Food Microbiology; counting
techniques; methods for evidence of absence of bacterial strains; alternative (fast) methods of
research
Identification of micro-organisms - general methods; API Kits
Strains studied in Food Mycobiology (description, culture and pathogenic characters) - Coliformes - E.
coli, Salmonella, Listeria monocytogenes, Staphylococcus aureus, Bacillus, Clostridium etc.; Yeasts
and bacteria involved in alteration process
Destruction and elimination of micro-organisms - temperature, chemical agents and their use in
conservation of food products
Introduction to HACCP (Hazard Analysis control Critical Point)
Seminar’s topic:
Identification and description of lactic bacteria in food
Assay for antibacterial activity of the isolated lactic bacteria
Description of unwanted bacteria and pathogens in food: coliformes, Staphylococcus aureus etc.
Using API kits for identification of Entérobacteria
References
Microbiologie Alimentaire Tome 1. Aspect microbiologique de la sécurité et de la qualité des aliments,
Coordinateurs : C.M.Bourgeois, J.F.Mescle, J.Zucca, Collection Sciences et Techniques
Agroalimentaires, TEC DOC 11, rue Lavoisier, 75384 Paris cedex 08
Norme française NF ISO 7218 (document AFNOR), Microbiologie des aliments, Règles générales
pour les examens microbiologiques
Course’s name: Food Chemistry
CREDITS ECTS: 6
Semester II
84
Course’s holder: Reader Professor PhD Rénato FROIDEVAUX, IUT „A” Sciences and Technologies
University Lille, France
General topic:
Chemical composition of food products – introduction; water; lipids; digestible sugars; fibres; proteins;
vitamins; mineral elements
Grains - general introduction; the grain; starch; proteins; bread making process
Fruits and vegetables - constituents of plant cell wall; saccharides and inverted sugar; additives
Meat - general introduction; the carcases; obtaining meat; food treatments and their effects on
chemical constituents of meat
Eggs and egg products - chicken egg; egg’s nutritional value; egg products – main technologies; egg
products – functional proprieties; usage of egg products
Seminar’s topic:
Measurement of lactose in milk using the Bertrand method
Measurement of lactose in milk using the 3.5-DNS method
Quality control for fats: Hübl parameter, saponification, acidification and esterification
Measurement of casein in milk using the Kjeldhal method
Assay for total volatile nitrogen
Conservation of C vitamin in fruits and vegetable
References
Abreges de Biochimie alimentaire de C. Alais et G. Linden, Ed. Masson
Biochimie agro-industrielle: valorisation alimentaire de la production agricole de G. Linden et D.
Lorient, Ed. Masson
Course’s name: Informatics and Biological Systems Modelling
CREDITS ECTS: 6
Semester II
structures.
Learning basic skills in using bio-modelling software designed (general parameters and specific
parameters).
Biophysics, Cell Biology, Genetics.
General topic:
Algorithms and models - Introduction to Bioinformatics; Evolutionary algorithms applied in
computational biology; Parallel Monte Carlo simulation in molecular evolution of HIV and the immune
response: Approaching the issue. Models; Mechanisms of parallelism with MPI; Parallel random
number generator; Preliminary results of the simulation.
Differential evolutionary algorithms for dynamic analysis “in vivo” for pentozo-phosphate and glycolise
routes in Escherichia coli - Mathematical models. Estimate model parameters; Estimated kinetics
parameters with DE; Simulation results and analysis of stability.
Intensive computational simulation cell models - Simulation methods for chemical kinetics; Biological
aspects, genetic regulation; Parallel algorithms for biological systems; Parallel simulation. Spatial
modelling of cellular systems; Algorithms for modelling cell colonies.
Introduction to biological databases - Types of databases: Relational database; Object-oriented
Data Bank of Japan (DDBJ); Secondary databases (SWISS-PROT, PIR, DALI); Specialized biological
databases (TAIR, EBI); Interconnections between biological databases, solutions and limitations.
Query and data mining of existing biological databases: Heuristic methods (BLAST and FASTA);
85
(Macromolecular Crystallographic Information File). 4.2.5. Other data structures (NMR-specific
Molecular computational biology - Basic concepts in computational biology; A heuristic approach to
comparing biological sequences; Comparison of parallel and distributed sequences.
Folding proteins - Folding proteins. Method of parallel replication of molecular dynamics processing;
Method of replication dynamics of molecular transformations; Protein folding based on the method of
replicating the dynamics of molecular transformations; Completion of protein structure by the method
of replicating the dynamics of molecular transformations; Parallel evolutionary algorithms to detect
protein structures.
Seminar’s topic:
Organizing, structuring and accessing primary biological databases, query mechanisms, obtain the
necessary
data:
Primary
GenBank
nucleotide
sequence
database
in
NCBI
(http://www.ncbi.nlm.nih.gov/Genbank),
European
Molecular
Biology
Laboratory
(EMBL)
(http://www.ebi.ac.uk/embl/index.html)
and
DNA
Data
Bank
of
Japan
(DDBJ)
(http://www.ddbj.nig.ac.jp).
Organizing, structuring and accessing databases secondary biological mechanisms query, obtaining
the
necessary
data:
SWISS-PROT
(http://www.ebi.ac.uk/swissprot/access.html),
PIR
(http://pir.georgetown.edu/pirwww/pirhome3.shtml), DALI (http://www2.ebi.ac.uk/dali/).
Specialized biological databases: TAIR (http://www.arabidopsis.org/), interconnection between the
databases, solutions and limitations.
Introduction to the NAMD program (Scalable Molecular Dynamics) simulation program for
biomolecular complexes and molecular dynamics systems, algorithms based on the interactions
between atomic force fields. Configuration parameters. Input and output files. X-PLOR program used
to generate input files containing data describing the molecular system to be simulated by NAMD.
Introduction to VDM Program (Visual Molecular Dynamics) analysis and visualize files generated by
retrieval of a .pdb files (Protein Data Bank) of the databases described above. Analysis and its view.
Extracting mmCIF file (Macromolecular Crystallographic Information File). Analysis and its view.
Create .psf files (protein structure file) using the .pdb source files from above biological databases.
Preparing data for simulation; Setting main parameters of the NAMD simulation program. Calculation
parameters for wan der Waals interactions and electrostatic nature. The test for distance interaction.
Overall electrostatic integration phase; Configuring additional parameters of NAMD simulation
program: constraints and restrictions, energy minimization, balance temperature control, pressure
control, limiting conditions, analysis and application of diverse external forces (constant forces,
external electric field, motion constraints, rotation constraints), the calculation of free energy for
Proteomics. Analysis of protein expression technologies. Polyacrylamide gel electrophoresis.
Differential In-Gel electrophoresis.
References
Acids Res. 25:3389–402.
Bergeron B. 2003. Bioinformatics Computing. Prentice Hall PTR, ISBN: 0-13-100825-0.
Associates.
for discovering regulatory sequences in genomes. Curr. Genomics 4:557–68.
Parallel Computing for Bioinformatics and Computational Biology (Models, Enabling Technologies,
and Case Studies). 2006. Edited by Albert Y. Zomaya. The University of Sydney, Australia, John Wiley
& Sons, Inc.
86
84.
Inc. ISBN: 0-471-20200-2
Course’s name: Genomics
CREDITS ECTS: 6
Semester II
Objectives: Fundament the bases of study in molecular ecology and phylogeny
Experimental models of study in molecular ecology and phylogeny
Presenting the importance of molecular studies applicable in ecology, phylogeny and phylogeography
Molecular concepts about different aspects of evolution and systematic.
Recommended/obligatory courses: General Genetics, Molecular Genetics.
General topic:
DNA structure
Human Genome
Chromosomes and plasmids
Genes
Gene expression regulation
Genome size and organization
Viral genome
Prokaryotic genome
Eukaryotic genome
Human and Primate genome
Mice and rat genome
Dipters and annelids as models for human diseases
Genome sequencing projects
Genomics, practical aspects
Seminar’s topic:
Molecular markers in phylogeny and phylogeography
Applied phylogeography
Systematic biology
Sample prelevation and preparation techniques
Hereditary information support analysis methods
DNA sequencing
Phylogenetic trees – types, models and building methods
Phylogenetic inference and distance based methods
Evolutive distances estimation and amino acids rate substitution
Parsimony theory – methods and models
Tree accuracy and statistic methods of analysis
Molecular clock and linearized trees
Nucleotide and Amino acid ancestral sequences
Genetic polymorphism and evolution
References
Lesk M. A., 2007 – Introduction to genomics, Oxford University Press.
Martins P. Emilia, 1996 – Phylogenies and comparative method in animal behaviour, Oxford University
Press. Nei M., Kumar S., 2000 – Molecular evolution and Phylogenetics, Oxford University Press.
Semple C., Steel M. A., 2003 – Phylogenetics, Oxford University Press.
87
Van Straalen N. M., Roelofs D., 2006 – An introduction to ecological genomics, Oxford University
Press
Course’s name: Proteom
CREDITS ECTS: 6
Semester III
Course’s holder: Lecturer PhD student Eugen UNGUREANU
Objectives: To know and to use fundamental concepts and language concerning proteome and
metabolic mechanisms involved in synthesis and catabolism of proteins.
Acquiring necessary skills to work in laboratory with proteins/proteome.
Recommended/obligatory courses: General Chemistry, General Biochemistry, Enzymology, Cell
Biology, Metabolic Transformations Of Sugars And Lipids, Genetics, Structural organizations of
Proteins and Nucleic Acids, Metabolic Transformations of Aminoacids, Proteins and Nucleic Acids.
General topic:
Fundamentals of structure and metabolism of proteins. Primary, secondary, tertiary and quaternary
structure of proteins. Protein interactions. Proteins as genome expression. Identifications of proteins
modifications. Methods for identifying and separation for proteins. Proteome applications in molecular
biology and medicine. Computers and proteome.
Seminar’s topic:
Qualitative and quantitative protein analysis. Electrophoresis of proteins. Methods for qualitative and
quantitative protein analysis. Enzymes identification in polyacrylamide gell. Computers and proteome
analysis.
References
Artenie Vlad - Biochimie, Editura Universitatii „Al.I.Cuza” Iasi, 1991;
Artenie Vlad, Tanase Elvira – Practicum de biochimie generala, Centrul de Multiplicare al Univ.
„Al.I.Cuza” Iasi, 1981;
Dumitru I.F.- Biochimie, EDP, Bucuresti, 1980;
Daniel C. Liebler, John R Yates III – Introduction to proteomics – Tools for the new Biology, Humana
Press Inc, 2002;
Daniel Chasman - Protein Structure Determination, Analysis, and Applications for Drug Discovery,
Routledge, 2003;
Carl Branden, John Tooze – Introduction to protein structure, Gar5land Publishing, 1999; Engelbert
Buxbaum – Fundamentals of protein structure and function, Springer Verlag, 2007;
Clive Dennison - A guide to protein isolation, Kluver Academic Publishers, 2002;
C. A. Glasbey, G. W. Horgan – Image Analysis for the Biological Sciences, John Wiley & Sons, 1995
Teaching methods: Lectures, euristic conversation, debates, brainstorming, Case study
Course’s name: Biochemical Transformations Involved in Food Preservation
CREDITS ECTS: 6
Semester III
Course’s holder: Reader Professor PhD Zenovia OLTEANU
Objectives: The knowledge of food preservation methods and biochemical transformations supported
by the application of these techniques.
Recommended/obligatory courses: General biochemistry, Metabolism, General chemistry
General topic:
Food preservation methods.
The role of food additives in preservation.
Biochemical transformations in flesh, fish and eggs during freezing and preservation. Proteins and
lipids alteration in freezing process and flesh and fish preservation in this state.
Transformations in milk and milk derivative products during freezing and depositing.
88
Food preservation by antiseptics. Sulphur dioxide influence about vegetal tissue and biochemical
component part. Hydrogen peroxide action about milk biochemical component part.
Transformations in dried vegetable products. Oxidative degradations of dried vegetables.
Transformations in dried flesh. Oxidative degradations of dried animal origin products
Physique-chemical transformations of dried milk derivative products component part.
No enzymatic degradations of dried foods.
Enzymatic transformations of dried foods.
Pathways for dried food stability amplification (inert atmosphere, active atmosphere, antioxidants,
packing protection)
Thermal sterilization influence about vegetable canned goods.
Thermal sterilization influence about flesh.
Thermal sterilization influence about milk.
Seminar’s topic:
Chemical transformations because food preservation by different methods.
Optimization contingencies of chemical endogenous enzymes catalysed reactions by exogenous
enzymes contribution for preservation harmful reduction.
The choice and the fix of the best food preservation methods with a view to maintain products
appearance.
The usage risks for some no authoritative addition and treatments.
Practical solutions for food packing with bioactive films, modern researches results
Pasteurization, concentration, drying or milk sterilization, methods looked through staple biochemical
transformations.
Biochemical aspects about raw milk preservation through lactoperoxidase system.
References
Burzo, I., Toma, S., Craciun, C., Voican, V., Dobrescu, Aurelia, Delian, Elena – 1999, Fiziologia
plantelor de cultura, vol. I, Ed. Stiinta, Chisinau, 352-354.
Cachita-Cosma, Dorina, Sandu, Camelia – 2000, Biotehnologie vegetala, vol. I, Ed. Mira “Design”,
Sibiu.
Cojocaru, D. C. – 1997, Enzimologie, Ed. Gama, Iasi.
Delincee, H., Pool-Zobel, B. – 2000, Genotoxic properties of 2-dodecylcyclobutanone, a compound
formed on irradiation of food containing fat, Radiation Physics and Chemistry.
Diehl, J.F. – 1995, Safety of irradiated food, Marcel Dekker, N.Y.
Dumitru, I. F. – 1980, Bichimie, Ed. Did. si Pedag., Bucuresti.
Dumitru, I. F., Dana Iordachescu – 1974, Enzime – structura si mecanisme, Ed. Med., Bucuresti.
Dumitru, I. F., Dana Iordachescu – 1981, Introducere in enzimologie, Ed. Med., Bucuresti.
Lehninger, A. L. – 1987, Biochimie, vol I, Ed. Tehnica, Bucuresti.
Lehninger, A. L. – 1992, Biochimie, vol II, Ed. Tehnica, Bucuresti.
McGee, H. – 2004, On Food and Cooking, Scribner, pp 448 - 450, "Wood Smoke and Charred Wood".
Molins, R. – 2001, Food irradiation - Principles and applications, Wiley Interscience, N.Y.
Moraru, C., Giurca, V., Segal, Br., Banu, C.,Costin, Gh., Motoc, D., Pana, N – 1971, Biochimia
produselor alimentare, Ed tehnica, Bucuresti.
Satin, M. – 1993, Food irradiation, Technomic, Lancaster.
Sipher, A.T. – 1968, Food Irradiation: An FDA Report. FDA Papers.
Sommers, C.H. – 2005, Toxicology Testing Of The Unique Radiolytic Product 2Dodecylcyclobutanone.
Sommers, C.H., Fan, X. – 2006, Food Irradiation Research and Technology, Blackwell Publishing,
Ames, IA.
Urbain, W.M. - 1986 Food irradiation, Academic Press, Orlando.
Course’s name: Biochemistry of Nutrition
CREDITS ECTS: 6
Semester III
Course’s holder: Reader Professor PhD Anca Mihaela NEGURA
89
Objectives: Biochemical characterization of foods: composition, metabolism, energy values and
nutritive necessary
Knowledge about the role of different foods compounds.
Recommended/obligatory courses: Structural biochemistry, Carbohydrates and lipids metabolism,
Proteins and nucleic acids metabolism, Food toxicology.
General topic:
Introduction
The general chemical composition of food: water, carbohydrates, lipids, proteins, enzymes, vitamins,
hormones, pigments, minerals, fibbers, bioactive substances;
Characterization of animal food: milk and derivates, eggs, meat, fish;
Characterization of vegetal food: cereals, vegetables, fruits;
Nutrition notions: nutritive necessary, basal metabolism, composition and energy of the food ration.
Seminar’s topic:
Chemical analysis of different compounds from meat and derivates, milk and derivates, fruits,
vegetables.
References
Artenie Vl.,Tanase Elvira, Practicum de biochimie generala. Ed. Univ. "Al.I.Cuza", Iasi, 1981
Alais G., Linden, G., Biochimie alimentaire, 2 edition, Editura Masson, Paris-Milan-Barcelon-Bonn,
1993
Dumitru, I.F., Biochimie, Editura Didactica si Pedagogica, Bucuresti, 1980
Garban, Z., Tratat elementar de biochimie, vol 1, Editura Mirton, Timisoara, 1993
Moraru, C., Giurca, V., Segal, B., Banu, C., Costin, D., Motoc, D., Pana, N., Biochimia produselor
alimentare, Editura Tehnica, Bucuresti, 1971
Stryer L., Biochemistry, Fourth edition, Editura W.H. Freeman and Company, New-York, 1995.
Teaching methods: Lectures, euristic conversation, modelling – brainstorming, experiment,
observation.
Course’s name: Industrial Enzymes
CREDITS ECTS: 6
Semester III
Course’s holder: Lecturer PhD ELENA CIORNEA
Objectives: Familiarize students with general notions that refers to nomenclature, classification and
enzymes structure and, respectively, enzymatically cofactors, their properties, cinetics of enzymatically
reactions, regulation of enzymatically activity and notions of immobilization enzyme concept,
determination of optimal conditions of immobilization and practical utilization of immobilized enzymes.
Recommended/obligatory courses: General Chemistry; General Biochemistry; Structural Biochemistry;
Analytic Biochemistry; Genral Enzimology.
General topic:
The course is structured per chapters that refer to nomenclature, classification and enzymes structure
and, respectively, enzymatically cofactors, their properties, cinetics of enzymatically reactions,
regulation of enzymatically activity and notions of immobilization enzyme concept, sources of industrial
interest enzymes, obtains of industrial enzymes, utilization of enzymes in industry.
Seminar’s topic:
Separation and purification of vegetable catalase;
Separation and purification of invertase from malt;
Separation and purification of alcooldehidrogenase from malt;
Inclusion of Saccharomyces cerevisiae cells in agar gel.
References
Cojocaru, D. C. – 2005, Enzimologie practica, Ed. TEHNOPRESS, Iasi
Cojocaru, D.C., Zenovia Olteanu, Elena Ciornea, Lacramioara Oprica, Sabina Ioana Cojocaru, 2007 Enzimologie generala, Ed. Tehnopress, Iasi
90
Nuta, Gh., Busneag, C. – 1977, Investigatii biochimice, Ed. Did. si Ped. Bucuresti
Pelmont, Y. – 1992, Enzymes, Presses Universitaires de Grenoble.
Teaching methods: Lectures, explication, demonstration, modelling-brainstorming, euristic
Course’s name: Selected Microrganisms for Food Industry
CREDITS ECTS: 6
Semester III
Objectives: Acquisition of further knowledge on the fundamental processes of selection and use of
starter cultures in industrial fermentations.
Presentation of the methodology of cultivation of the selected micro-organisms.
Knowledge of the strategies of selection and improvement of the biosynthesis parameters of microorganisms with a view to obtaining industrial strains.
Genetics.
General topic:
Introduction
Scientific bases for the selection of micro-organisms for food industry - Implications of microorganisms for the development of bio-industries; Groups of micro-organisms selected for the food
industry; Strategies of selecting micro-organisms with superior synthesis properties
Production and use of the micro-organisms selected for food industry - General considerations on the
growth of the selected cultures; Systems for cultivation of selected micro-organisms; Types of selected
cultures; Physical-chemical factors that influence the growth kinetics of the selected cultures;
Compounds inhibiting the growth of the selected cultures; Obtaining the standardized inoculum;
Aseptic conditions for inoculum preparation and transfer; Influence of the inoculum on biotechnological
processes
Quality control of selected cultures - Control of the biotechnological properties; Genetic control;
Microbiological control
Methods employed to evaluate the microbiological quality of the selected cultures
Methods of preservation and marketing of the selected cultures
Seminar’s topic:
Isolation and obtaining methods for selected pure culture
Cultivation of selected micro-organisms used in food industry
Quantitative and qualitative examination techniques for micro-organisms from raw and pasteurised milk
Micro-organisms isolated from fermented products (yogurt, cheese, pickles beverages)
Isolation and testing of some yeast strain with high fermentative capacities
Conservation and maintenance of selected micro-organisms synthesis potential
Organization of selected micro-organisms collection used in food industry.
References
Bahrim Gabriela, 1999, Microbiologie tehnica, Editura Evrika, Braila.
Bourgeois C.M., Mescle J.F., Zucca J.,1998, Microbiologie alimentaire, tome 1, 2, Ed. Apria, Paris.
Dan Valentina, 1999, 2000, Microbiologia produselor alimentare, vol. I, II, Ed. „Alma” Galati.
Dan Valentina, Oancea Ioana, Kramer Cristina, Zara Margareta, Tofan Clemansa, 1991, Controlul
microbiologic al produselor alimentare, Ed. Univeristatii din Galati.
Dunca Simona, Octavita Ailiesei, Erica Nimitan, Stefan Marius, 2004, Microbiologie aplicata, Ed.
Tehnopress, Iasi.
Gams W., Hoekstra E. S., Aptroot A. (Eds.), 2000, CBS Course of Mycology, Fourth Edition,
Centraalbureau voor Schimmelcultures, Baarn, Delft, The Netherlands.
Magearu V., 1988, Controlul analitic al proceselor microbiologice, Editura Tehnica, Bucuresti.
Mihail D.N., 1998, Biotehnologia si bioingineria, Editura Stiintifica si Enciclopedica, Bucuresti.
Oprean L., 2002, Microbiologia produselor alimentare, Ed. Universitatii „Lucian Blaga” Sibiu.
Samson, R. A., Van Reen–Hoekstra Ellen, 1988, Introduction to food borne fungi, Centraalbureau voor
Schimmelcultures, Baarn.
91
Course’s name: Methabolic Pathways in Agro-Alimentary Materials
CREDITS ECTS: 8
Semester IV
Course’s holder: Professor asoc. PhD Vlad ARTENIE
Objectives: Familiarize the students with the latest research regarding anabolic and catabolic
processes taking place natural in raw agro-alimentary materials, processes which produce both useful
and un-wanted compounds.
Recommended/obligatory courses: General Chemistry, Biochemistry, Structural Biochemistry,
Microbiology
General topic:
Introduction : Quality and innocuousness of raw agro-alimentary
Metabolic transformations in raw agro-alimentary leading to useful compounds: Alcoholic fermentation;
Lactic fermentation; Other fermentation processes
Metabolic transformations in raw agro-alimentary leading toxic compounds: Toxic compounds naturally
occurring in agro-alimentary products; Toxic compounds and biological pollution; Toxic compounds
formed by processing row agro-alimentary materials.
Seminar’s topic:
The assay of alcohol dehydrogenase activity.
The assay of lactate dehydrogenase activity.
Measurement of ethanol in fermented fluids
The measurements of lactate in fermented fluids.
The determination of some antioxidants
The determination of some antioxidative enzymes activities
References
Artenie, Vl. G. – 1976, Curs de Chimie Biologica, Ed. Univ. “Al. I. Cuza” Iasi
Artenie Vlad, Ungureanu Eugen, Negura Anca Mihaela – 2008, Metode de investigare a
metabolismului glucidic si lipidic. Editura PIM, Iasi
Cojocaru, D. C. – 2005, Enzimologie practica. ETP Tehnopress, Iasi.
Teaching methods: Lectures, explication, demonstration, modelling-brainstorming, euristic
Course’s name: Microbiology of Foods and the Breguency of Contaminant Microorganisms
CREDITS ECTS: 8
Semester IV
Course’s holder: Professor PhD Maria Magdalena ZAMFIRACHE
Objectives: Achieving minimum observing, analyzing, interpreting capacities and flexible onset of the
theoretic and practical knowledge from the study themes of the discipline. Using applied biology
specific information and methods to form future specialists.
Recommended/obligatory courses: Biochemistry, Microbiology.
General topic:
Natural sources of contaminated micro-organisms pollution for food (soil, water, air microbiota;
biological sources). General information on food microbiota (specific microbiota; unspecific
microbiota). Evaluation means for degree of micro-organism charge on foods. Risk of consuming
contaminated food. Qualitative and quantitative analysis of food microbiota. Legislation peculiarities on
microbiological quality of foods and applied STASS in food industry.
Seminar’s topic:
Quality and quantity analysis techniques of the air and water consumed by the population.
92
Quality and quantity analysis regarding the food products microbiota. Legislative demands of The
European Union regarding microbiological quality of the food products. Microbiological control of meat
and meat products. Microbiological control of milk and derived products. Microbiological control of
primary and auxiliary vegetal material (grains and derived products, oleaginous seeds and derived
products, fruit and vegetables and derived products). Microbiological control of basic products in beer,
wine, fruit beverages and finish products making. Papers suggested by the master students.
Student visit at the Laboratory of wine quality check – Copou Iasi wine research station.
References
Dan V., 1999-2000 – Microbiologia produselor alimentare, vol. I, II, Ed. "Alma" Galati.
Dan V., Oancea I., Kramer C., Zara M., Tofan C., 1991 – Controlul microbiologic al produselor
alimentare, Ed. Univ. Galati.
Horaicu C., 2004 – Monitorizarea integrata a mediului, Ed. Tipografia Moldova Iasi. Brown L., 1992 –
Probleme globale ale omenirii, Ed. Tehnica Bucuresti.
Brown L, 1994 – Probleme globale ale omenirii, Ed. Tehnica Bucuresti.
Manescu S., 1989 – Microbiologia sanitara, Ed. Medicala Bucuresti.
Nimitan E., Ailiesei O., Dunca S., Comanescu St., 1998 – Metode si tehnici de microbiologie, Ed.
Universitatii “Al. I. Cuza“ Iasi.
Oprean C., Suciu O., 2003 – Managementul calitatii mediului, Ed. Academiei Romane, Bucuresti.
Voicu V, 2002 – Combaterea noxelor in industrie, Ed. Tehnica Bucuresti.
Teaching methods: Lectures, debates, case study, demonstration, euristic conversation, modelling –
brainstorming
Course’s name: Computer Modelling of Biochemical Process
CREDITS ECTS: 7
Semester IV
structures.
Modelling of highly complex protein structures.
Biophysics, Cell Biology.
General topic:
What is bioinformatics and bio-modelling - Introduction, brief history; Objectives and the scope of
bioinformatics and bio-modelling; Bioinformatics today limitations.
Fundamentals of protein structures - Primary structure of proteins; Types of secondary and tertiary
structures found in proteins; Classification of the biochemical conformation of protein folding;
Structural classification of protein conformations in their folding; Quaternary structure of proteins, the
combination of several polypeptide chains.
Determination of macromolecular structures - X-ray crystallography; Nuclear magnetic resonance
spectroscopy; Electronic microscopy.
Introduction to biological databases - Types of databases: Relational database; Object-oriented
Data Bank of Japan (DDBJ); Secondary databases (SWISS-PROT, PIR, DALI); Biology Databases
specialized (TAIR, EBI); Interconnections between biological databases, solutions and limitations;
Query and data mining of existing biological databases; Heuristic databases (BLAST and FASTA);
(macromolecular Crystallographic Information File); Other data structures (NMR-specific
Bioinformatics and structural bio-modelling - Determination of primary three-dimensional structure of
proteins; Prediction of protein secondary structure; Prediction of secondary structure in globular
proteins; Transmembrane protein secondary structure prediction;
93
Prediction of tertiary structure of proteins: Modelling by homology; Assessment of the twisting and
wrapping; Evaluation techniques for prediction of protein structures.
Proteomics - Technology for assessment of protein expression; Post-translational modifications;
Protein-protein interactions.
Seminar’s topic:
Organizing, structuring and accessing primary biological databases, query mechanisms, obtain the
necessary
data:
Primary
GenBank
nucleotide
sequence
database
in
NCBI
(http://www.ncbi.nlm.nih.gov/Genbank),
European
Molecular
Biology
Laboratory
(EMBL)
(http://www.ebi.ac.uk/embl/index.html)
and
DNA
Data
Bank
of
Japan
(DDBJ)
(http://www.ddbj.nig.ac.jp).
Organizing, structuring and accessing databases secondary biological mechanisms query, obtaining
the
necessary
data:
SWISS-PROT
(http://www.ebi.ac.uk/swissprot/access.html),
PIR
(http://pir.georgetown.edu/pirwww/pirhome3.shtml), DALI (http://www2.ebi.ac.uk/dali/).
Specialized biological databases: TAIR (http://www.arabidopsis.org/), interconnection between the
databases, solutions and limitations.
Introduction to the NAMD program (Scalable Molecular Dynamics) simulation program for
biomolecular complexes and molecular dynamics systems, algorithms based on the interactions
between atomic force fields. Configuration parameters. Input and output files. X-PLOR program used
to generate input files containing data describing the molecular system to be simulated by NAMD.
Introduction to VDM Program (Visual Molecular Dynamics) analysis and visualize files generated by
retrieval of a .pdb files (Protein Data Bank) of the databases described above. Analysis and its view.
Extracting mmCIF file (Macromolecular Crystallographic Information File). Analysis and its view.
Create .psf files (protein structure file) using the .pdb source files from above biological databases.
Preparing data for simulation; Setting main parameters of the NAMD simulation program. Calculation
parameters for wan der Waals interactions and electrostatic nature. The test for distance interaction.
Overall electrostatic integration phase; Configuring additional parameters of NAMD simulation
program: constraints and restrictions, energy minimization, balance temperature control, pressure
control, limiting conditions, analysis and application of diverse external forces (constant forces,
external electric field, motion constraints, rotation constraints), the calculation of free energy for
Proteomics. Analysis of protein expression technologies. Polyacrylamide gel electrophoresis.
Differential In-Gel electrophoresis.
References
Altschul, S. F., Boguski, M. S., Gish, W., and Wootton, J. C. 1994. Issues in searching molecular
sequences databases. Nat. Genet. 6:119–29.
Acids Res. 25:3389–402.
Bergeron B. 2003. Bioinformatics Computing. Prentice Hall PTR.
Chen, Z. 2003. Assessing sequence comparison methods with the average precision criterion.
Bioinformatics 19:2456–60.
Dubchak, I., and Pachter, L. 2002. The computational challenges of applying comparative-based
computational methods to whole genomes. Brief. Bioinform. 3:18–22.
Geer, R. C., and Sayers, E.W. 2003. Entrez: Making use of its power. Brief. Bioinform. 4:179–84.
Associates.
Hannenhalli, S., and Levy, S. 2001. Promoter prediction in the human genome. Bioinformatics 17
(Suppl):S90-6.
Hehl, R., and Wingender, E. 2001.Database-assisted promoter analysis. Trends Plant Sci. 6:251–5.
Higgins, D. G. 2000. Amino acid-based phylogeny and alignment. Adv. Protein Chem. 54:99–135.
94
Nei, M., and Kumar, S. 2000. Molecular Evolution and Phylogenetics. New York: Oxford University
Press.
Nunes de Castro L., Von Zuben F. J. 2005. Recent Developments in Biologically Inspired Computing.
Idea Group Publishing. ISBN:1591403126
Ohler, U., and Niemann, H. 2001. Identification and analysis of eukaryotic promoters: Recent
computational approaches. Trends Genet. 17:56–60.
for discovering regulatory sequences in genomes. Curr. Genomics 4:557–68.
Patnaik, S. K., and Blumenfeld, O. O. 2001. Use of on-line tools and databases for routine sequence
analyses. Anal. Biochem. 289:1–9.
Qiu, P. 2003. Recent advances in computational promoter analysis in understanding the
transcriptional regulatory network. Biochem. Biophys. Res. Commun. 309:495–501.
Rombauts S., Florquin K., Lescot M., Marchal K., Rouze P., and van de Peer Y. 2003. Computational
approaches to identify promoters and cis-regulatory elements in plant genomes. Plant Physiol.
132:1162-76.
Salemi, M., and Vandamme, A. M. 2003. The Phylogenetics Handbook – A Practical Approach to DNA
and Protein Phylogeny. Cambridge, UK: Cambridge University Press.
84.
Inc.
Thornton, J. W., and DeSalle, R. 2000. Gene family evolution and homology: Genomics meets
phylogenetics. Annu. Rev. Genomics Hum. Genet. 1:41–73.
Whelan, S., Lio, P., and Goldman, N. 2001. Molecular phylogenetics: State of the art methods for
looking into the past. Trends Genet. 17:262–72.
ENVIRONMENTAL SCIENCES
¾ ENVIRONMENTAL CONSULTANCY
In the mostly countries member of the European Union, each important economic unit
has one environmental department, with one delegate in the Executive Board of the unit. Still
in 1988, the European Community Commission took in financial charge one project in order
to create the Environmental Consultancy Institute (Institute de l’ Eco-Conseil) in Strasbourg;
after this, similar institutes appeared in the majority countries from the Western Europe.
In the conditions of the recently including of Romania in the European Union, it is
necessary nor only the legislation and economic strategies’ harmonisation on long-terms but
also to form specialists that can assure their implementation in our country.
This master degree programme started in 2008 and is a proposal for a large group of
bachelors in natural sciences, agronomy and forestry, but also in human sciences (sociology,
psychology, social assistance, etc.) or in technical domains, the curriculum including some
courses of “ecological culture”.
The curriculum of this master degree program follows to assure scientifically
competence, juridical and administrative knowledge, communication and educational
abilities, in order to change the attitude and the daily behaviour. The graduates will obtain a
95
complete image of the whole environmental problems and economical interests of the human
society’s complexity, being able to understand and analyse the environmental problems,
learning the methodology to solve these problems, to elaborate urgent strategies to manage
the environmental problems.
The dissertation paper’s topic represents one exercise to solve a problem that can
appear in the daily activity of one environmental consultant.
The environmental consultant is a multidisciplinary specialist that can be the
coordinator of one team of very different specialists, having abilities to:
• to mediate between the interests and relations of different partners, building bridges for
“everybody goodness”’ consortiums,
• to introduce the environmental problems and their prevention in the local and regional
development projection and implementation,
• to help the decision makers through different solution proposals,
• to establish the basis of environmental projects and environmental impact studies,
• to organise and coordinate educational programs for different groups of people and
stakeholders.
Practically, one environmental consultant make the relation between the economically
interest of the human society and the necessity to preserve a high quality of the
environmental in order to obtain an increasing of the human life’s quality.
environmental protection agencies;
local administration;
governmental authority;
institutes and agencies that are doing impact studies;
administrations of national parks and biosphere reserves;
consultancy agencies for the economic sector;
non-governmental organisations;
research laboratories from universities;
universities.
96
Faculty of Biology
APROVED
Valid for :
1st Year: 2009 - 2010
2nd Year: 2010 - 2011
PROGRAMMES OF STUDY
University degree domain: Environmental’ sciences
Specialisation: Master degree – Environmental consultancy
No.
Name of the subject
C
S
L
Credits
Pr
Evaluation type
Colloquium
Exam
1
Ecosystems and Risk Factors
2
1
0
7
I
2
Environment's Pollution - Assessment and Control
2
0
2
8
I
3
Ecological Restoration
2
2
0
8
I
4
Environmental Legislation
1
2
0
7
I
7
5
2
30
TOTAL
nd
2
ST
SEMESTER (1
0
4
YEAR)
1
Communication and Communication Strategies
2
2
0
6
II
2
Environment's Protection and Sustainable Development
2
1
0
6
II
3
Environment and the Territorial Planning
1
1
0
6
II
4
Ecotourism's Principles
2
2
0
6
II
5
Principles for the Nature's Conservation in the Protected Areas
1
1
0
6
II
8
7
0
30
2
2
0
7
TOTAL
rd
nd
3 SEMESTER (2
1
0
5
YEAR)
Environmental Ethics
III
2
Principles of the Environmental Education
2
2
0
8
III
3
Management of the Environmental Problems
1
2
0
8
III
4
Environmental Politics and Strategies
2
1
0
7
III
7
7
0
30
TOTAL
th
nd
4 SEMESTER (2
0
4
YEAR)
1
Impact Assessment Studies
2
2
0
6
IV
2
Bioindicators and the Environmental Quality's Assessment
2
0
2
6
IV
3
European Politics and the Environmental Projects' Funding
1
1
0
6
IV
4
Management of the Environmental Projects
2
2
0
6
IV
5
Magnum practicum
0
0
6
6
IV
6
(facultative)
0
0
90
5*
IV
TOTAL
7
5
8
30
No.
1
2
0
5
No. of classes
Examination
Sem.
Credits
type
C
A
levels)
1
2
28
28
14
14
5
5
Exam
Exam
3
28
14
5
Exam
4
4
0
42
5
Colloquium
5
2
14
28
5
Exam
3
98
6
3
1
2
3
4
4
14
28
5
Exam
30
5E+1C
5
Exam
IMPORTANT NOTES:
The master’s degree in Biology, specialization ENVIRONMENTAL CONSULTANCY can be conferred only to students that have obtained 120
credits in the obligatory disciplines from the hereof syllabus.
99
Course’s name: Ecosystems and Risk Factors
CREDITS ECTS: 7
Semester I
Course’s holder: Lecturer PhD Mircea-Dan MITROIU
Objectives: Thoroughly study of the ecosystems and their natural and anthropogenic risks
Establish correlations between the anterior knowledge and those specific to the current
discipline.
Introduction
Aquatic ecosystems and risk factors - Types of aquatic ecosystems; The human impact on
running waters; The human impact on lakes; The human impact on subterranean waters;
Supra-exploitation of aquatic resources; Aquatic invasive species
Terrestrial ecosystems and risk factors - Types of terrestrial ecosystems; The decrease of the
biocenose biodiversity; Physical alteration of the soil; Habitat fragmentation; Terrestrial invasive
species
Agricultural ecosystems and risk factors - Types of agro-ecosystems; Intensive agriculture and
its consequences; Genetically modified organisms (GMOs)
Seminar’s topic:
Case studies: the UNESCO nature sites and the risk factors
Threatened species listed by IUCN.
References
Ehrich P. R. & Ehrich A. H., 1970. Population. Resources. Environment. Issues in Human
Ecology. W. H. Freeman and Company.
Goudie A. 2006. The Human Impact on the Natural Environment. Sixth Edition. Blackwell
Publishing.
Mustata M., Mustata Gh., Andriescu I., Mitroiu M.-D. 2006. Biologia daunatorilor animali. Ed.
Junimea Iasi.
Parvu C. (edit.), 1980. Ecosistemele din Romania. Ed. Ceres, Bucuresti.
Pricope F. 2000. Poluarea mediului si conservarea naturii. Univ. din Bacau.
Resurse World Wide Web.
Sciama, Y. 2008. Nourrir 9 milliards d’individus. Science & Vie, Hors Série, 243: 69-79.
Turk A., Turk J. & Wittes J. T., 1972. Ecology. Pollution. Environment. W.B. Saunders
Company.
Teaching methods: Lectures, Case study, euristic conversation, modelling - brainstorming
Course’s name: Environment's Pollution - Assessment and Control
CREDITS ECTS: 8
Semester I
Course’s holder: Reader Professor PhD Lacramioara IVANESCU
Objectives: Acknowledging the global problems such as the greenhouse effect, acid rains,
rarefaction of the ozone layer, forests’ drying and death, disappearance of plants and animals
species.
Acknowledging the specialized terminology in evaluating and managing the environmental
problems caused by the anthropogenic factor .
Recommended/obligatory courses: Vegetal and animal ecomorphology. Environmental
Chemistry, Vegetal Taxonomy, General Ecology, Vegetal Ecophysiology, Environmental
Pollution and Protection, Methodology for the drawn up of the impact studies, Environmental
Law, legislation, policies and strategies.
General topic:
Draw up the Strategic Environmental Plan (SEP): Analysis and diagnosis; Making the SEP;
Verification, completion and implementation. Study: SEP for Fortus S.A. Suggestions regarding
the administration of the waste dumps. Ecologic audit. Crisis management. Case study: Kurk’s
submarine’s crisis. Social responsibility of a company from the ecologic field – case study:
Tylenol.
General information on the pollution phenomenon: evaluation of the present knowledge
concerning the global problems such as greenhouse effect, acid rains, rarefaction of the ozone
stratospheric layer, forests’ drying and death, plants and animals species’ disappearance.
Aspects of the psychology of change (ecological movements, conventions and international
treaties, World Bank, International Monetary Fund, retechnologization, how well do we
understand the significance of the concepts “perceptual threshold”, “ecological education”,
“natural capital”, “nature’s limits”, “ecological risks”?). Conclusion of a new world partnership:
protection of the environment; satisfaction of the population’s needs; remodelling of international
institutions; citizens’ involvement.
Atmospheric pollution: sources and industrial emissions. Pollution of the ocean: sources
(leakages and discharges on land; gas emissions from the land; navigation and accidental
leakages; discharges into the ocean; sea mining, petroleum or gas drilling). Chemical pollution
of drinking water. Protection of sea fishing. Soil pollution: wastes discharges; use of fertilizers
and pesticides; deposit of the emissions initially ejected into the atmosphere; water of
contaminated rains from the atmosphere and water from irrigations.
Radioactive pollution. Nuclear accidents and their effects on life: terrestrial vegetal and animal
communities (analysis: October 7th, 1957- Windscale, Great Britain; January 3rd, 1961- Idaho
th
th
Falls, U.S.A.; October 5 , 1966 - Detroit, Michigan; November 19 , 1971 - Monticello,
th
Minnesota; April 26 , 1986 - Cernobîl, the ex- Soviet Union). Testing nuclear weapons in the
atmosphere and underground. French nuclear tests from the coral islands of Mururoa and
Fangtaufa from the Pacific between 1966 and 1996. What are nuclear wastes, what do we know
about them and, above all, what do we know about the regions they are stored in? What do we
know about the atomic power plant of Cernavodă, commissioned on April 17th, 1996, which
uses Candu Canadian technology?
Arms race: the biggest source of air, water and soil pollution. Evaluation of the military impact
on environment and people, what does “making peace with the environment” means? Ten
reasons for which the arming is detrimental for the environment? Devastation of environment:
the armed conflicts from Vietnam, Central America and Persian Gulf, Afghanistan (study cases).
China, January 2007 – testing anti-satellite missile.
Biological weapons (anthrax, botulism, pest, smallpox). Biological war. Conference on biological
arms, November 19th, 2001, Switzerland. A re-evaluation of human being’s state of safety.
Group psychology in approaching the mechanism of a real danger: invisible weapons.
Evaluation of medical ecological risks: chemical burden; cancer and environment; nervous
system in danger; gender, reproduction, and development; immune system; safety and
science’s limits.
Food containing genetically modified elements. Evaluation of the impact on ecosystems by
introducing into the culture the genetically modified plants. Evaluation of their impact on human
health. Are there such products on the Romanian market? Are these products correctly
labelled?
Seminar’s topic:
The titular professor will present two case studies from her own doctoral thesis concerning the
Effects of atmospheric pollution from the Borzesti (Bacau county) and Bicaz (Neamt county)
industrial areas on vegetation.
Outreach application: MOLDOCIM S.A. Bicaz (outreach observations and biological material
sampling in view of the evaluation of the impact on vegetation by using biological markers;
Integrated Environmental Authorization).
Practical activity in the laboratory. Identification, testing, selecting and using certain
morphological, structural and ultrastructural biomarkers in order to evaluate the level of the
anthropic impact on a system’s biodiversity. Histo-chemical analysis of biological samples from
the MOLDOCIM S.A. Bicaz area (identification of the defence compounds from the polyphenols
group – pollution biomarkers; interpretation of the sections with structure modifications;
elaborate a database containing elements of foliar symptomatology; laboratory equipments and
necessary reactive agents; elaboration of dissertations based on the achieved results).
Practical laboratory activity: Foliar surface – biomonitor in powder atmospheric pollution; short
presentation of the present state of the knowledge in this field; biological material’s sampling
and processing methodology in view of the SEM examination (Scanning Electron Microscope).
Interpretation of the gathered images. Cuticular micromorphology – biological marker answering
to environmental changes. – Aspects concerning the influence of the atmospheric pollution on
101
the vegetation from the area surrounding an industrial platform. Presentation of certain case
studies by some of the students who treated this argument in their diploma paper (AMBRO S.A.
Suceava, Antibiotice S.A. Iasi, Fortus S.A., Iasi, Safir S.A. Vaslui, Sofert S.A. Bacau). Scope:
presentation of personal experiences during the outreach study and the way the information is
processed. Which is the actual situation of the outreach activity and which is the information
posted on the industrial unit’s site?
References
Gostin Irina, 2007 – Biomarkeri structurali la plante, Ed. Universitatii „Al.I.Cuza”, Iasi
Lloyd A., Mathews P., 2002 – Bioterorismul, flagelul mileniului III, Ed. Hyperion, Cluj Napoca.
Ivanescu Lacramioara, Toma, C., 2003 – Influenta poluarii atmosferice asupra structurii
plantelor, Ed. Fundatiei Andrei Saguna, Constanta
Pisoschi Aurel, Aurel Ardelean, 2007 – Aspecte metodologice in cercetarea stiintifica, Editura
Academiei Romane
Stiglitz E. Joseph, 2008 – Mecanismele globalizarii, Ed. Polirom, Iasi
Treshow M., Anderson F., 1989 - Plant Stress from Air Pollution. John Wiley & Sons, Chichester ·
New York · Brisbane · Toronto · Singapore
Teaching methods: Lectures, exposure, explication, debates, brainstorming, observation,
experiment, demonstration
Course’s name: Ecological Restoration
CREDITS ECTS: 8
Semester I
Course’s holder: Reader Professor PhD Carmen GACHE
Objectives: Definition of the ecological restoration
Knowledge of some theoretical and practical models of ecological restoration
Forming and developing one ecological concept of the relation humanity - environmental
Understanding of the practical value of the ecological restoration for the biodiversity’s
conservation and life quality’s improvement.
Introduction
Ecological restoration – a new concept for the nature’s conservation or old model of territorial
arrangement?
Practical ecological restoration: Ecological restoration in the marine ecosystems – potential and
limits; Ecological restoration of the wetlands; Ecological restoration of the lakes ecosystems;
Ecological restoration in the terrestrial ecosystems - Steppe, prairie; Temperate Forests;
Tropical Forests.
Reintroduction/re-colonisation of some species in ecosystems: Premises and preliminary
studies; Vegetal and animal Communities; Minimal population; American Buffalo (Bison bison) –
one model to safe o species in extinction risk situation and other examples.
Ecological restoration – basis for a new research topic and for the natural capital’s conservation
Seminar’s topic:
Case study – Ecological restoration in the Danube Delta: premises, done programmes, future
projects
Case study – The Ciobarciu wetland (Iasi County), cooperation Romanian-Netherlands; field trip
application
Practical premises of the ecological restoration in different ecosystems from Romania: planning
and modelling an ecological restoration project in one terrestrial ecosystem
Action Plan for one animal species.
References
Foundation Development and Peace, 1993 – In the afternath of the Earth Summit, Ed. Eine
Welt, Germany
Jordan, W.R. III, Gilpin, M.E., Aber, J.D., 1990 – Restoration Ecology, Ed. Cambridge Universty
Press, New York, SUA
Marin, Georgeta, Schneider, Erika si colab., 1997 – Reconstructie ecologica in Rezervatia
Biosferei Delta Dunarii/Romania, Ed. ICCDD, Tulcea, Romania – WWF, Auen Institut, Germany
102
Primack, R. B., Patroescu, Maria, Rozylowicz, R., Ioja, C., 2002 – Conservarea diversitatii
biologice, Ed. Tehnica, Bucuresti
Sutherland, W. S., 2000 – The Conservation Handbook: rsearch, management and policy, Ed.
Blackwell Science, Oxford, UKStugren, B., 1992 – Ecologie teoretica, Ed. Sarmis, Cluj Napoca
Stefan N., 2005 – Fitocenologia si vegetatia Romaniei, Ed. Univ.”Al. I. Cuza” Iasi
Vadineanu, A. (editor) si colab., 2004 – Managementul dezvoltarii: o abordarea sistemica, Ed.
Ars Docendi, Bucuresti
***, 2004 – 10 years of restoration in the Danube Delta Biosphere Reserve, Ed. INCDDD,
Tulcea, Romania – WWF, Auen Institut, Germany
Course’s name: Environmental Legislation
CREDITS ECTS: 7
Semester I
Objectives: Knowledge of the national, European and international legislation and of strategies
for the natural environment protection; presentation of the impact of the anthropogenic actions
upon the ecosystems; formation of the ecological conception regarding the sustainable use of
environmental resources.
Recommended/obligatory courses: Botany, Zoology, Hidrobiology.
General topic:
The environment: definition and classification
Man intervention in the ecosphere equilibriums
Principles of the international environmental law
Communitarian environmental law: framework directives, directives, regulations and appendices
Environmental legislation in Romania
Delivering of the environmental licences
Seminar’s topic:
The management of the environmental information
Action fields of the environmental legislation
Policies of environmental protection
Stability and reserves of the ecological systems
Elements of environment toxicity
Evaluation and management of the ecological risk.
References
Bobica N., 1994 – Elemente de ecologie si dreptul mediului inconjurator, Edit. Fundatiei
Chemarea, Iasi
Dutu M., 1995 – Dreptul international si comunitar al mediului, Edit. Econ., Bucuresti
Dutu M., 1998 - Dreptul mediului. Tratat. Vol I si II, Edit. Econ., Bucuresti
Hey C., 1995 - Legislatia de mediu a Uniunii Europene, Friends of the Earth Europe,
Rhododendron, Tg. Mures
Lupan E., 1993 – Dreptul mediului, Edit. Lumina Lex, Bucuresti
Marinescu D., 1996 - Dreptul mediului inconjurator, Casa de edit. si presa "Sansa" SRL, Bucuresti
Nicoara M., 2003 - Legislatia mediului, Ed. Univ. "Al.I. Cuza" Iasi
Noortmann M., Vasiliu F., Talnaru D.M., 1997 - Legislatia Mediului-Mijloc de Actiune, Fundatia
Milieukontakt Oost – Europa
Sion I.G., 1990 - Ecologie si drept international, Edit. St. si Enciclop., Bucuresti
Wates J., 1995 - Ghid practic pentru imbunatatirea accesului public la informatiile de mediu,
Friends of the Earth Europe, Rhododendron Tg. Mures
*** 1997 - Guide to the approximation of European Union Environmental Legislation, Romanian
version, Commission of the European Communities, Brussels SEC(97) 1608
*** 1995 - Legea protectiei mediului, Monitorul oficial al Romaniei, 30 decembrie 1995
Teaching methods: Lectures, debates, Case study, modelling-brainstorming.
103
Course’s name: Communication and Communication Strategies
CREDITS ECTS: 6
Semester II
Course’s holder: Lecturer PhD Simina STANC
Objectives: The creation of an attitude regarding „the problem of communication”, by becoming
aware of the positive and negative effects of our own communication style, and by becoming
sensitive to the receptor; knowing of mechanisms and ways of persuasion; knowing the
implications of the new discoveries in neuro-bio-psychology regarding the emotional
intelligence, their impact on the communication; becoming aware that the persuasion process
represents a dynamic folding of messages exchange, both verbal and non-verbal, adapted
according to the process to become.
Introduction (The functions of the language. Levels and types of communication)
Self-knowing and communication (States of the ego. Communication by one’s own inner
resources. Difficulties in the personal development. Mental optimization. Training and control of
speech. Training of the abilities to listen)
Interpersonal communication (The role of knowing the receptor. Perception of messages.
Strategies to cope with the roles of power. The conversation – conversation startegies.
Persuasive strategies)
Ways of communication. (Non-verbal communication. Written communication in public relations.
Verbal exposition. Communication for employment)
Neuro-linguistic Programming techniques.
Seminar’s topic:
Non-verbal language. Applications.
Written communication. Applications
Mental training.
Emotions management
Understanding the receptor strategy
Coping with the resistance of the receptor, and problems’ solving
The power of example in education.
Speech training. Applications.
The power of precision, faith and personal belief – attributes of a successful communication.
Coping with practical situations of communication regarding the environment protection.
References
Anthony Robins, 2001, Putere nemarginita – Stiinta dezvoltarii personale, Editura Almatea,
Bucuresti
Anthony Robins, 2002, Descopera forta din tine, vol. 1, 2, Editura Curtea Veche, Bucuresti
Candea Rodica, 2004, Comunicand pentru a convinge. Ghid, editat de SC Candea
Consulting&Development SRL Cluj Napoca
Chiru Irena, 2003, Comunicarea interpersonala, Editura Tritonic, Bucuresti
Collett Peter, 2005, Cartea gesturilor – cum putem citi gandurile oamenilor din actiunile lor,
Editura Trei, Bucuresti
Dinu Mihai, 2004, Fundamentele comunicarii interpersonale, Editura All.
Goleman Daniel, 2005, Emotiile distructive, Editura Curtea Veche, Bucuresti
Goleman Daniel, 2005, Inteligenta emotionala, Editura Curtea Veche, Bucuresti
Knight Sue, 2004, Tehnicile programarii neuro-lingvistice, Editura Curtea Veche, Bucuresti.
Nothstine W.L., 1998, Arta convingerii, Editura Codex, Bucuresti
Oachesu I.Viorel, 2004, Noua cultura a comunicarii, Editura Amalthea
Prutianu Stefan, 2005, Antrenamentul abilitatilor de comunicare, vol. 1 si 2, Editura Polirom, Iasi
Szekely Andy, 2003, NLP –Calea succesului, Editura Almatea, Bucuresti
Tolle Eckhart, 2004, Puterea prezentului. Ghid de dezvoltare spirituala, Editura Curtea Veche,
Bucuresti
Teaching methods: Lectures, Case study, modelling-brainstorming.
104
Course’s name: Environment's Protection and Sustainable Development
CREDITS ECTS: 6
Semester II
Course’s holder: Lecturer PhD Anisoara STRATU
Objectives: Uptake and correct use of specific notions, concepts and principles of discipline
The creation of an systematic way of thinking of the investigation skills, specific to this matter
and of the responsible behaviour development concerning environmental issues.
Recommended/obligatory courses: General Biochemistry; General Ecology, Ecosystems and
risk factors, Environment’s pollution – assessment and gestion, Environmental legislation.
General topic:
Environment and human activity - Natural factors of degradation of ecosphere; The impact of
human activity on the environment: modalities and consequences
Environmental protection, integrated part of sustainable development; The concept of
sustainable development; Objectives, principles, strategies of environmental protection;
Protection of natural resources; Conservation and sustainable use of natural resources in
traditional societies; Human health protection and promotion; Economical and social tackle of
environment protection issues; Environmental monitoring systems
Ecological education – need for sustainable development; The importance of ethic elements in
education; Principles and characteristics of ecological education/ Ways of ecological education
training; The importance of ecological education in solving the environment issues
Seminar’s topic:
Water analysis: determination of organoleptic, physical and physico-chemical indicators;
determination of some indicators of water pollution
Chemical – health control of some food groups
Sustainable exploitation of ecosystems
Hygiene of human habitate
Alternative sources of energy
Wastes – source of income
Ecological products
Visit to worn-out water cleaning Station Dancu.
References
Acatrinei Gh.,1994 – Poluarea si protectia mediului ambiant. Centrul de multiplicare al Univ. Al.
I. Cuza Iasi.
Chifu T., Murariu Alexandrina, 1999 – Bazele protectiei mediului, Ed. Universitatii „Al. I. Cuza”
Iasi.
Costica N (coord. stiintific), Ciumasu E., Costica M., Stanc S., Stratu A., Surubaru B., Cozma
D., Baciu L., Mesnita G.,Grozavu A., Cucos C., Ceobanu C., Curelaru V., Diac G., Ghetau R.,
2007- Ghid de formare metodologica in domeniul educatiei de mediu (EM) - versiune destinata
studentilor Ed. Corona, Iasi.
Ionescu I., Sahleanu V., Bindu G., 1989 – Protectia mediului
inconjurator si educatia
ecologica. Ed. Ceres, Bucuresti.
Manescu S., Cucu M., Diaconescu Mona Ligia, 1994 – Chimia sanitara a mediului, Ed.
Medicala, Bucuresti.
Popa M., 2001 - Concepte si tendinte privind poluarea mediului inconjurator, Ed. Quo Vadis, Cluj Napoca
Pricope F., 2001 – Poluarea mediului si conservarea naturii, Universitatea Bacau.
Primack R., Patroescu M., Rozylowicz L., Ioja C., 2002 – Conservarea diversitatii biologice. Ed.
Tehnica, Bucuresti.
Rojanschi V., Bran F., Diaconu Gh., 1997 - Protectia si ingineria mediului, Ed. Economica,
Bucuresti
Zamfirache M.M., Murariu A., Olteanu Z., Stratu A., (coord. Toader Chifu), 1997 – Bazele
protectiei mediului inconjurator. Caiet de lucrari practice. Ed. Univ. „Alexandru Ioan Cuza”, Iasi
www.mediu.ro
Teaching methods: Lectures, euristic conversation, demonstration, experiment, observation,
debates, case study.
105
Course’s name: Environment and the Territorial Planning
CREDITS ECTS: 6
Semester II
Course’s holder: Lecturer PhD Anisoara STRATU
Objectives: The assimilation of some general notions concerning territory arrangement in this
modern context
The establishment of some correlations between previous notions and some specific notions of
this domain.
Creation of few main skills concerning to area modelling based on ecological and aesthetics
principles.
The assimilation of a proper vocabulary for an easy understanding of complex perspective on
these specific problems.
Recommended/obligatory courses: Plants’ Taxonomy, Environmental legislation, Ecosystems
and risk factors
General topic:
General considerations referring to relation people-environment - Types of environment;
Environment – people - dwelling relation
General considerations referring to territory arrangement - Territory arrangement in European
context; Territory arrangement in national context: Public institutions for urbanism and
systematization of areas; Documentation of territory arrangement and urbanism; Legislation;
Representation of natural and anthropogenic environment into town-planning and territory
arrangements; Notions of general cadastre; Arrangement types
Green areas - component of studies of territory arrangement - General notions; The functions
and classification of green areas; Types of green areas; Technical standards; The main
characteristics of species recommended to be used in arrangements from the green areas
Studies concerning to environment problems – a part of sustainable development planning:
Stages of an impact study; Indicators used for an impact study; Structure of a evaluative report
used for analysis of the impact on environment; Methods and techniques used for evaluation of
impact on environment
Seminar’s topic:
Case studies: plans of territory arrangement (sections) and urbanity plans; the arrangement of
natural park.
Environment Licence ⁄ Environment Agreement (documents; laws; activities which have direct
consequences on environment).
The biological peculiarities of some species used at green areas arrangement/ Techniques
element referring to arrangement of some green area.(application at Botanical Garden)
Aesthetic principles and specific categories used for landscape projection; landscape styles.
References
Benedek J., 2004 - Amenajarea teritoriului si dezvoltarea regionala. Ed. Presa Universitara
Clujeana, Cluj-Napoca.
Defour D., Baucher I., 1977 – Sistematizarea localitatilor rurale. Ed. Ceres, Bucuresti.
Glavan V., 2003 – Amenajarea turistica a teritoriului. Ed. Alma Mater, Sibiu.
Minea Elena, 2002- Amenajarea teritoriului. Ed. Accent . Cluj - Napoca.
Mitoiu C., Stan M., Parisi S., Parvulescu M., 2005 – Amenajarea teritoriului rural (indrumator
pentru lucrari practice, seminarii si teste pentru autoEvaluation). Ed. Bren, Bucuresti.
Muja S., 1994 – Dezvoltarea spatiilor verzi in sprijinul conservarii mediului inconjurator. Ed.
Ceres, Bucuresti.
Negrutiu Filofteia, 1980 - Spatii verzi. Ed. Didactica si Pedagogica, Bucuresti.
Teaching methods: Lectures, euristic conversation, observation, debates, case study
Course’s name: Ecotourism's Principles
CREDITS ECTS: 6
Semester II
Objectives: To understand eco-tourism’s principles;
To know the touristy value of the natural patrimony;
Initiation in stable development strategy of eco-tourism.
106
Recommended/obligatory courses: Biogeography, Bases of environment protection, Tourism
geography, Biological field trips
General topic:
Introduction
Natural conditions and touristy localization - Touristy importance of the relief; Touristy
importance of the climate; Touristy importance of the waters; Touristy importance of flora and
vegetation; Touristy importance of the fauna; Touristy importance of the human beings; Touristy
localization: from image to project development
Ecological bases of tourism - Definitions and principles; Eco-tourism characteristics; The
degradation of natural ecosystems by tourism activities; Ecology of tourism recourses
Projection and development of eco-tourism - Impact, functionality and stable development;
Protection of natural capital; Protection of human patrimony and socio-economic impact; Ecotourism politics
Seminar’s topic:
Romanian eco-tourism resources - Coastline eco-tourism; Mountainous eco-tourism; Lake ecotourism; Fluvial eco-tourism; Town eco-tourism; Rural-ethnographic eco-tourism; Cultural ecotourism; Frontier eco-tourism.
References
Chifu T., Murariu Alexandrina, 1999, Bazele protectiei mediului inconjurator, Ed. Universitatii
„Alexandru Ioan Cuza” Iasi
Cianga N., 2001, Romania: geografia turismului, Ed. Presa Universitara Clujeana, Cluj-Napoca
Iatu C., Muntele I., 2002, Geografia economica, Ed. Economica, Bucuresti
Jolondcovschi Al., Florea S., 2001, Turismul ecologic si rural: realitati si perspective, Ed.
Prometeu, Chisinau
Muntele I., Iatu C., 2003, Geografia turismului. Concepte, metode si forme de manifestare
spatio-temporala, Ed. Sedcom Libris, Iasi
Negulescu M., Vaicum L., Patru C., Ianculescu S., Bonciu G., Patru O., 1995, Protectia mediului
inconjurator, Ed. Tehnica, Bucuresti
Pacurar Al., 1999, Turismul international, Ed. Presa Universitara Clujeana, Cluj-Napoca
Pearce D., 1993, Géographie du tourisme, Nathan, Paris
Popovici Eveline, 1998, Studiul mediului inconjurator. Dimensiuni europene, Ed. Universitatii
„Alexandru Ioan Cuza” Iasi
Teaching methods: Lectures, debates, Case study, modelling - brainstorming.
Course’s name: Principles for the Nature's Conservation in the Protected Areas
CREDITS ECTS: 6
Semester II
Objectives: Knowledge of the biodiversity value, national, European and global priorities, and of
strategies for capitalization and conservation of bio-resources; presentation of the impact of the
hunting, fishing and excessive sampling upon the biodiversity of certain ecosystems; formation
of the ecological conception regarding the sustainable use of bio-resources.
Recommended/obligatory courses: Botany, Zoology, Ecology, Hidrobiology
General topic:
Biodiversity role in the stability and regulation of the ecological systems
The evolution of the nature conservation concept
Programmes for the introduction and reintroduction of populations
Policies for biological diversity protection
Regime of protected areas
The pan-European strategy for nature conservation
The network Nature 2000
The global network of biosphere reserves
Ecotourism role in nature conservation
Ecological reconstruction.
Seminar’s topic:
The bio-monitoring
Techniques of biodiversity conservation: in vivo; in vitro
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Strategies for sustainable exploitation of the natural resources
Nature conservation in the world
Nature conservation in Romania
Protected areas and the nature’s monuments’ situation
The concept of Red Data Book
Case studies: Whales overexploitation; Seals hunting.
References
Ardelean A., Maior C., 2000 - Management ecologic, Edit. Servo, Arad
Nicoara M., 2009 – Legislatie, institutii si politici de mediu, Editura Tehnopress, Iasi
Nicoara M., 2009 – Monitoring ecologic, Editura Tehnopress, Iasi
Nicoara M., Bomher E., 2004 - Ghidul ariilor protejate din judetul Iasi, S.C. Tipografia Moldova,
Iasi
Primack R.B., Patroescu M., Rozylowicz, Ioja C., 2002 – Conservarea diversitatii biologice, Ed.
Tehnica, Bucuresti
*** 1995 - Objectivesle de Management pentru Conservarea Biodiversitatii si Dezvoltare
Durabila in Rezervatia Biosferei Delta Dunarii, Romania, Information Press, Oxford
*** 1999 - A future for Europe's nature and biodiversity, Proceedings, European Centre for
Nature Conservation - Tilburg
*** 2002 - Dezvoltarea prevederilor pentru conservarea naturii in Romania, Institutul European din
Romania, Bucuresti, 190 p.
*** 2003 – Natura 2000 si padurile “Provocari si oportunitati”. Ghid de interpretare, Comisia
europeana, Vassen
*** H.G. nr. 230/2003, privind delimitarea rezervatiilor biosferei, parcurilor nationale si parcurilor
naturale si constituirea administratiilor acestora
Teaching methods: Lectures, euristic conversation, case study, video-projection
Course’s name: Environmental Ethics
CREDITS ECTS: 7
Semester III
Course’s holder: Reader Professor PhD Carmen GACHE
Objectives: Understanding of the environmental ethics concept
Knowledge of some ethic concepts
Forming and developing an ethical attitude in the relation humanity – environmental
Knowledge of the sustainable development concept’s complexity
Knowledge of the consequences to implement the sustainable development strategies for
humanity and ecosphere.
Introduction – Environmental ethics, a new moral system?
Ethical aspects of the relation human species – natural environment Moral dilemma in the
historical evolution of different philosophy and religious systems
Individual rights and community rights
Human rights, animal rights, nature rights
Sustainable development’s principle, a new vision on the long-term interests of the humanity
Social aspects of the sustainable development
Ecological aspects of the sustainable development
Seminar’s topic:
Moral and immoral, correctly and convenient in the relation of the humanity with the
environmental
Young today, leaders tomorrow – are we prepared to take responsibilities?
Anthropocentric ethic versus bio-centric ethic
Conscience, attitude and involvement in elaboration and implementation of the new strategies
to develop the human society without the environmental degradation
Demographic increase of the humanity, natural resources exploitation and prevent the support
capacity of biosphere
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Connection scientific research – technological progress – environmental society, the key for the
human species surviving with the biodiversity’s conservation on Terra.
References
Baird Callicott, J., 1987 – The conceptual foundations of the land ethic, Companion to a Sand
County Almanac, University of Wisconsin Press
Eisntein, A., 1992 – Cum vad eu lumea, Ed. Humanitas, Bucuresti
Foundation Development and Peace, 1993 – In the afternath of the Earth Summit, Ed. Eine
Welt, Germany
Goodpaster, K.E., 1978 – On being morally considerable, The Journal of Philosophy,LXXV, 6
308 - 325
Hellden, G., 2000 – Environmenthal ethics and the environmental education, Ed. Univ. din
Thessaloniki, Greece
Leopold, A., 1949 – The land ethic, A Sand County Almanac, University of Wiscosin Press
Lorenz, K., 1996 – Cele opt pacate capitale ale omenirii civilizate, Ed. Humanitas, Bucuresti
Lorenz, K., 1998 – Asa zisul rau. Despre istoria naturala a agresiunii, Ed. Humanitas, Bucuresti
Regan, T., 1980 – Animal rights, Human wrongs, Environmental Ethics, vol.2, 2: 99 – 120
Rolston, H.III, 1991 – Challenges in Environmental ethics, Ecology, Economics, Ethics: The
Broken Circle, Yale University Press, New Haven, London
Course’s name: Principles of the Environmental Education
CREDITS ECTS: 8
Semester III
Objectives: Assuring active implying of students in activities of ecological education.
Knowing principles, resources and methods of ecological education implementing.
Applying principles and methods of ecological education in different educational contexts.
Manifesting a proactive, scientific and methodological proved behavior in the field of education.
Transmitting and scientifically proving an appropriate value system for environment protection
and for sustainable development.
Ecological education: definition, conceptual evolution
Necessity of ecological education achievement in Romania
Principle of ecological education - Principle of axiological orientation; Principle of pragmatic
orientation; Principle of interdisciplinary; Principle of experiential learning; Principle of curricular
actualisation and development
Objectives and finalities of ecological education
Informational and space - temporal resources
Methodology of ecological education implementation
Seminar’s topic:
Applying principles and methods of ecological education achievement in formal and non- formal
contexts.
Achievement of case – studies and projects of ecological education for real situation and
problems (inclusively for those included in Local Plan of Action for Environmental Protection)
References
Bocos, Musata, 2002, Instruire interactiva. Repere pentru reflectie si actiune, Ed Presa
Universitara Clujeana, Cluj;
Kolb D.A., 1984, Experiential Learning: Experience as the Source of Learning and
Development, Prentice-Hall.
Miron S., 2003 - Portofoliul European pentru Educatia Mediului Inconjurator, Indrumar pentru
profesori si elevi, TEPEE; Socrates, Comenius
Momanu M., 2002, Introducere in teoria educatiei, Ed. Polirom, Iasi;
Vaideanu G., 1988, Educatia la frontiera dintre milenii, EDP, Bucuresti;
* * * - Sustainable Development. Critical Issue, OECD Report, 2001, www.oecd.org
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Teaching methods: Case study, learning through cooperation, euristic conversation, lectures
Course’s name: Management of the Environmental Problems
CREDITS ECTS: 8
Semester III
Course’s holder: Lecturer PhD Mircea-Dan MITROIU
Objectives: Acquire the management abilities regarding environmental problem solving.
Thoroughly study of different concepts related to ecological management, biodiversity
management, management of protected area, environmentally friendly agricultural management
etc.
Recommended/obligatory courses: Ecosyustems and risk factors
General topic:
Introduction
Environmental problems and the human factor
Team work and the environmental problem solving
Environmental problem approaches
The stress and the environmental problems
The correct identification of the environmental problems
Types of environmental problems
Planning the environmental problem solving
Establish the objectives
Identify the solutions
Take the decisions
Experiment the solutions.
Seminar’s topic:
Practical exercises regarding environmental problem solving.
Construction of management plans for different Romanian protected areas.
References
Dumitru, C., 2004. Management si marketing ecologic. O abordare strategica. Ed. Tehnopress,
Iasi.
Hughes, J. W., 2007. Environmental Problem Solving. A How-To Guide. University of Vermont
Press, Vermont.
Horaicu, C., 2004. Monitorizarea integrata a mediului. Ed. Tipo Moldova.
Negrei, C., 1999. Instrumente si metode in managementul mediului. Ed. Economica, Bucuresti.
Primack, R.B., Patroescu, M., Rozylowicz, L. & Ioja, C., 2002. Conservarea diversitatii biologice.
Ed. Tehnica, Bucuresti.
Teaching methods: Lectures, euristic conversation, modelling-brainstorming, case study.
Course’s name: Environmental Politics and Strategies
CREDITS ECTS: 7
Semester III
Course’s holder: Professor PhD Maria Magdalena ZAMFIRACHE
Objectives: Achieving fundamental concepts regarding environmental management, knowledge
of the legal basis on national level and of the European Community States of action in its
protection and reparation.
General environmental management concepts; environmental politics and strategies (global,
regional and national); environmental strategies and politics in the EU: key moments; present
situation (legal basis; institutional and environmental politics actors; objectives; principles; action
programs; instruments of applying environmental politics); environmental strategies and politics
(durable development; environment protection active NGO promoting program; products
integrative politics (PIP); environmental volunteer accords; environment taxes and dues);
problematic aspects, trends, challenges; environmental community strategy (environmental
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skills of the European Community; types of European legislation; evolution of the community
politics in means of environment protection; environment and health European strategy –
SCALE); Romanian environmental strategies and politics: (short history; acceding negotiations;
institutional setting: national environmental politics supporting programs (priority establishing
criteria in environmental politics; economical reform and the environment; integrated strategies;
environmental politics (in a macroeconomical and sectorial scale); the national plan of
environmental protection); harmonizing Romanian legislation with the community judicial
settlement regarding environment.
Seminar’s topic:
The students will prepare during the seminaries papers on inherent subjects to the general
theme of the course. The debating problems (study cases where needed) will be announced
during the first seminar and will bring into discussion:
Research regarding the forecast and evolution of the environment quality (through comparative
analysis) in the EU and Romania (terrestrial environment and water management; antropic
activities evaluation on environment quality; techniques and methods of determining pollutants
and noxes; remedy methods and techniques; ecological reconstruction and rehabilitation;
recycling; reutilizing and eliminating the wastes; accidental pollution prevention).
Impact and ecotoxicology studies; expertise; product testing and analyzing; equipment and installations;
advising, environmental scales; environmental technological research, industrial pollution evaluation and
control; environmental quality management strategies.
Environmental strategies, diagnosis, methods, forecasts; consulting, advice, expertise; product
tests, technologies and equipments.
Strategies of securing the environment through management work in case of calamity.
A new editorial apparitions (within the course themes) presentation meeting will be held (based
on the reviews made by the students taking the course).
References
Brown R.L. - 1995 - Probleme globale ale omenirii. Starea lumii. Ed. Tehnica, Bucuresti;
Camasoiu Camelia - 1994 - Economia si sfidarea naturii. Ed. Economica, Bucuresti; Dumitru
Camelia – 2004 – Management si Marketing Ecologic. Ed. Tehnopress, Iasi; Horaicu C. – 2004 –
Monitorizarea integrata a mediului. Ed. Tipo Moldova, Iasi;
Kok, W. – 2003 - Enlarging the European Union: Achievements and Challenges?, Robert
Schuman Centre for Advanced Studies, European University Institute, Florence;
Manoliu M., Ionescu Cristina – 1998 - Dezvoltarea durabila si protectia mediului. H.G.A.,
Bucuresti.
Oprean C. – 2003 – Managementul calitatii mediului. Ed. Acad. Rom., Bucuresti; PETR J. – 2002Environmental Implications of Eastern Eniargement of the EU: The End of Progressive
Environmental Policy?, Robert Schuman Centre for Advanced Studies. European University
Institute, Florence;
Platon V. – 1997 - Protectia mediului si dezvoltarea economica. Ed. Didactrica si
Pedagogica, Bucuresti;
Pohoata I. – 2004 – Dezvoltarea durabila si politica de mediu in UE. Univ. “Al. I Cuza” Iasi, Centrul
de Studii Europene;
Popescu Maria – 1999 - Globalizarea si dezvoltarea trivalenta. Ed. Export, Bucuresti, Rojanschi
V. – 1997 - Economia si protectia mediului. Ed.Tribuna Economica, Bucuresti;
Voicu V. – 2002 – Combaterea noxelor in industrie. Ed. Tehnica, Bucuresti.
Teaching methods: Lectures, projections, demonstration, brainstorming, euristic conversation,
debates.
Course’s name: Impact Assessment Studies
CREDITS ECTS: 6
Semester IV
Course’s holder: Reader Professor PhD Lacramioara IVANESCU
Objectives: Knowledge of methodological issues in scientific research;
Learning the specific definitions in scientific research and technological development;
Initiating a proposal for a research project..
Recommended/obligatory courses: Vegetal and animal eco-morphology, Environmental
pollution and protection, Environmental law, Legislation, policies and strategies, Evaluation of
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environmental pollution and management, Ecological reconstruction, Ecosystems and risk
factors.
General topic:
The research and development system in Romania (units and research and
development institution; national strategy; plans, programs and grants for research and
development, innovation and their corresponding financing: national plan for research and
development and innovation; IMPACT program; sectorial plans; Romanian Academy plan;
the nucleus program; grants; human resources within the research, development and innovation
system).
International scientific research programs (The framework program of the European Union;
Other international programs: the COST program, Eureka program, NATO’s scientific program,
ESF-funded programs, bilateral programs).
Typology of scientific research and data collecting methods in scientific research
Stages in scientific research
Research project (drawing up a research project proposal; management of a research
project)
Presenting the scientific research’s results (oral and poster presentation, oral presentation at
scientific events, writing and presenting a thesis, writing an article for scientific publication,
drawing up and presenting a research report).
Evaluation of scientific research
Ethics in scientific research
Intellectual property
Seminar’s topic:
The professor in ordinary will present two particular cases from her own PhD thesis on Air
pollution effects in industrial areas Borzesti (Baaău County) and Bicaz (Neamt county) on
vegetation. Also, the professor will present the results obtained for another study case in which
the teacher acted as a grant director, covering The histo-anatomical investigations on
coniferous species in forest ecosystems at risk of drying. Purpose: 1. presenting the work
methodology in field and in laboratory in order to prepare students for future applications of
environmental projects aimed at assessing human impact on ecosystems; 2. information on
requirements for equipment and reagents; 3. teamwork: exact delimitation of the members’
duties.
What do impact projects stand for? How can students access funds for these projects? Are
students likely to obtain these funds? Study case: The CEEX contract for 2005-2008 - The use
of morphological, structural, ultra structural and biochemical biomarkers in assessing human
impact on biodiversity in Ceahlau National Park and adjacent area. Grant responsible: PhD
thesis coordinator Irina Gostin. I. Organization of scientific research program, research
objectives. II. Methodology of scientific research. Results of scientific research. Conclusions and
valorising results. III. Effects of valorising research results. Scientific information. IV. Ethics in
scientific research.
Develop a research project proposal respecting mandatory steps: initial stage - planning and
drafting stage - evaluation and contract stage - implementation phase – ending phase.
References
Ivanescu L., C. Toma, 2003 – Influenta poluarii asupra structurii plantelor, Ed. Fundatiei Andrei
Saguna, Constanta
Pisoschi Aurel, Aurel Ardelean, 2007 – Aspecte metodologice in cercetarea stiintifica, Editura
Academiei Romane
Stiglitz E. Joseph, 2008 – Mecanismele globalizarii, Editura Polirom, Iasi
Teaching methods: Lectures, exposure, explication, debates, brainstorming, observation,
experiment, demonstration
Course’s name: Bioindicators and the Environmental Quality's Assessment
CREDITS ECTS: 6
Semester IV
Course’s holder: Reader Professor PhD Mariana MUSTATA si Lecturer PhD Mihai COSTICA
Objectives: After they graduated this course, all student could realize following activities:
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To evaluate the quality of environment depending on identified bio-indicator species;
To follow the anthropic impact depending on few biological indicators;
To follow the answers of society at negative changes of the environment;
To evaluate waters quality depending on identified bio-indicator species (alga and animals).
Recommended/obligatory courses: General Ecology, Human Ecology.
General topic:
Environment and its quality – a global problem of humanity: anthropic impact on environment;
stage and quality of environment; society response at the modification of environment quality;
Evolution of determination methods used for environment quality;
Bio-indicators and hormones – their signification in evaluation of environment quality;
Biology and ecology of bio-indicators used for environment quality;
Environment indicators: definition of environment indicators and their used for evaluation of
environment quality; environment indicators classifications; establishing of specific criteria used
for environment description.
Evaluation of anthropic pressures on environment: pressure indicators in aerial and aquatic
media, flora, fauna and natural resources;
Evaluation of the level of environment quality;
Evaluation of society response at the environment modifications;
Actual environment problems described through specific indicators: indicators of anthropic
pressure on environment; indicators of environment level; indicators of response.
Using of bio-indicators for evaluation of waters qualities.
Seminar’s topic:
Evidencing of some bio-indicators used for determinations based on environment quality:
methods used for waters: determinations of water quality through some techniques (Kothé,
Liebmann, Knöpp, Pantle and Buck, Zeinka and Marvan);
Knowing biological indicators of waters quality which using alga and animals samples;
Solving of some present problems of the environment reflected through indicators: anthropic
pressure, environment characteristics; human society responses;
Reports concerning to performance inside of environment communications;
Standards ISO 14.001;
Characteristics of EMAS II;
European characteristics concerning to environment aspects.
References
Mustata, Gh., 1992, Lucrari practice de Hidrobiologie. Fasc. 1 si 2. Ed. Univ. „Al.I. Cuza” Iasi
Mustata Maria, Mustata Ghe., 2003 – „Probleme de ecologie generala si umana” Ed.
Universitatii „Al. I.Cuza” Iasi
Neagu, Anca Narcisa, Miron I., 2008, Bioindicatori de calitate a apelor curgatoare, Ed. Univ.
„Al.I. Cuza” Iasi
Popovici, Eveline, 1998, Studiul mediului inconjurator. Dimensiuni europene. Ed. Univ. “Al.I.
Cuza” Iasi
Pora, E.A., Oros, I., 1974, Limnobiologie si oceanologie. Hidrobiologie. Ed. Did. si ped.
Bucuresti Surugiu, V., 2008, Limnobiologie si saprobiologie. Compendiu de lucrari practice
Tutuianu, Ovidiu, 1999, Indicatori de mediu. Mediul inconjurator nr. 3, p. 24-32
Tutuianu, Ovidiu, 2006, Evaluationa si raportarea performantelor de mediu. Indicatori de mediu.
Ed. Agir, Bucuresti
Teaching methods: Lectures, Case study, brainstorming, investigation, demonstration.
Course’s name: Europeens Politics and the Environmental Projects' Funding
CREDITS ECTS: 6
Semester IV
Course’s holder: Reader Professor PhD Irina GOSTIN
Objectives: Ownership rules in the direction of European environmental legislation;
Knowledge of project development stages and the overall content of an application for funding
Identifying sources of funding in accordance with the proposed thematic area.
Knowledge base of European legislation on environmental policies;
113
Knowledge of strategic themes and priority areas of environmental research adopted by the
European Parliament and Council of Europe;
Developing a proposal for a European project;
European legislation in the field of environmental conservation (Habitat Directive (92/43 EEC),
Birds Directive (79/409 EEC), Nature 2000)
European Convention adopted as laws by the Romanian Parliament;
Funding requirements and possible sources of funding
The Framework - FP6 and FP7.
Seminar’s topic:
Steps to developing a project proposal to secure European funding: knowledge of legal basis for
its establishment; preparation and budget breakdown; self-evaluation of financial and
operational capacity; the importance of co-financing.
Project description - employment in the priority directions of research - clarity of objectives; clear
links to the content call; feasibility of activities; xpected results - indicating the exact intermediate
steps to be taken; the relationship cost-effectiveness; self-assessment of eligibility; procedures
for sending the proposal.
References
Brundtland H, 1987 – Report of the World Comission on Environement and developement – our
commun future, New York
Kramer L., 1992 – Focus on european low, Sweet and Maxwell, London
Elli L., 2006 – International Environmental Law: Fairness, Effectiveness, and World Order,
Cambridge University Press
Manoliu C., 2000 – Politica si legislatia europeana a mediului, Ed. HGA Bucuresti
Stanley J, Carcelle G., 1995 - The Environmental Policy of the European Communities, 2nd ed.,
Kluwer Publishing
Teaching methods: Lectures, brainstorming, experiment, demonstration.
Course’s name: Management of Environmental Projects
CREDITS ECTS: 6
Semester IV
Objectives: Knowing „life cycle” of an project
Knowing the project manager responsibilities
Writing an environmental project.
Recommended/obligatory courses: Environmental legislation, Europeens Politics and the
Environmental Projects' Funding
General topic:
General about projects - What are projects? - Basic features of projects
Project phases (basic processes) - Initiation; Planning/Design/Organisation; Implementing/
Execution/ Construction; Monitoring
Evaluation
Responsibilities and features of project manager: Duties of project manager; Planned approach
Identification and initiation of environmental projects - Project selection; Project aims, purpose
and dimensions; Risks and necessities; Project management team
Planning/projection/Organisation - Establishing the project activities; Work plan achievement;
Logic frame approach (LFA); Resource management; Time management - Gantt Diagram;
Project budget; Funds obtaining/project approval
Implementing/ Execution/ Construction - Work meetings; Communication and information
management; Budget and time management; Conflict management; Management of changes
Seminar’s topic:
Case studies
Example of best practice in project management
Applicative exercises of project writing.
References
Brown Mark, 1998, Project Management, - Hodder & Stoughton General.
Bartram Peter, 1999, The Perfect Project Manager, Random House Business Books.
Baum C. Warren, 1994, The Project Cicle, Library of Congress Cataloging in Publication Data.
114
Dumitru Oprea, Gabriela Mesnita, 2007, Fonduri Europene pentru Romania in perioada 2007 –
2013, Ed. Sedcom Libris, Iasi.
Efraim Turban, Meredith Jack R., Homewood Irwin, 1998, Fundamentals of Management
Science, Boston, Ma.
***, A Guide to the Project management Body of knowledge, 1996, Project Management
Institute.
www.managementul-proiectelor.ro
Teaching methods: Lectures, case study, brainstorming, investigation
115
FACILITIES PROVIDED TO STUDENTS BY THE
FACULTY
SOCIAL, DIDACTIC AND RESEARCH FACILITIES
PREMISES OF THE FACULTY OF BIOLOGY
Based on the structure, organization and the equipment that it is endowed with, the
Faculty of Biology represents the optimal place for the training and formation of biology
specialists.
These are completed by the social opportunities (accommodation, scholarships)
provided by “Al. I. Cuza” University, by means of the Faculty of Biology, as well as the
university mobility opportunities provided especially by means of the European academic
exchange programme SOCRATES-ERASMUS.
SOCRATES programme is a transnational cooperation programme in the educational
field, which is supported and financed by the European Union, by means of the European
Commission. Our university has implemented it since 1996. Mainly due to our ERASMUS
component, this programme has so far facilitated the accomplishment of almost 1000
opportunities of study mobility (Romanian students who go to European universities and
foreign students who come to our university).
After 1990, the Faculty of Biology has developed its collaboration programmes with
other similar institutions inside the country and abroad. Within the UNIVERSITARIA Consortium,
established in 1996, the Faculty of Biology from Iasi collaborates, both from a didactic
perspective, and by means of scientific research projects, with similar faculties within
associated universities (University from Bucharest, “Babes-Bolyai” University from Cluj, and
Western University from Timisoara).
Here are the foreign partners of our faculty with which we maintain relations of
collaboration and integration in European programmes: University of Liege (Belgium),
University of Gent (Belgium), Universite Catholique de l’Ouest Angers (France), Universite
d’Auvergne-Clermont Ferrant I (France), Universite des Sciences et Technologies Lille I
(France), Technische Universitaet Braunschweig (Germany), Albert-Ludwigs-Universitaet
Freiburg (Germany), Universitaet Konstanz (Germany), Aristotelio Panepistimio
Thessalonikis (Aristotle University of Thessaloniki – Greece), Universita degli Studi di Bari
(Italy), Universita degli Studi di Camerino (Italy), Universita degli Studi di Padova (Italy),
Universita degli Studi di Torino (Italy), University of Sussex (Great Britain), Rijksuniversiteit
Groningen (Netherlands), Universiteit Utrecht (Netherlands), Vrije Universiteit Amsterdam
(Netherlands), Universidade de Aveiro (Portugal), Catholic University of Portugal (Portugal),
University of Porto (Portugal), Universidad de Santiago de Compostela (Spain), Universidad
de Vigo (Spain), Mid Sweden University (Sweden), Swedish University of Agricultural
Sciences (Sweden), Uppsala Universitet (Sweden), Umeå University (Sweden).
Beside the teaching and research premises that have been previously presented
(lecture rooms, laboratories), the material endowment of the Faculty of Biology is completed
by a set of institutions where students develop practical on-site activities, which may help
them elaborate University-Degree and Dissertation Theses. These institutions have a long
tradition and an activity that is intimately connected to our own activity.
The faculty area includes all the premises and fields made available to the academic
community in order to develop teaching and research processes, as well as to provide
students with appropriate conditions of study and accommodation. Approximately 68% of
these premises are modernized and equipped with multimedia systems; about 6.5%
represents the area of the computer science laboratory.
The Faculty of Biology exploits a total area of 4956.68 m2, which is intended for
didactic activities, scientific research, administrative activities, libraries and storing rooms.
117
Situation of the existing spaces within the Faculty of Biology
No.
Professional Laboratory
Area
Percentage (%)
1
2
3
4
Molecular biology and biochemistry
Vegetal biology
Animal biology
Faculty, common
Total
1615.18
951.21
1443.14
947.15
4956.68
32.586
19.190
29.115
19.108
100.000
The rooms, which are intended to be practical work laboratories with students,
have a total area of 2595.98 m2 (52.37%). Approximately 41.07% of these places correspond
to the practical and research activities performed by students attending master’s degree and
doctor’s degree programmes.
The students of the Faculty of Biology use the Faculty Library and develop
specialized practical activities in specific Scientific Research Stations within “Alexandru Ioan
Cuza” University of Iasi, while these stations are scientifically coordinated by the Faculty of
Biology. The students of our faculty develop practical on-site activities at these locations in
order to elaborate their university-degree, dissertation and doctor’s degree theses.
As far as students’ accommodation is concerned, the Faculty of Biology has
rooms in the student hostels of “Alexandru Ioan Cuza” University of Iasi. Moreover, guest
professors or professors who are temporarily employed are accommodated in guest houses
and in hotel hostels “Gaudeamus” and “Akademos”. The students who come to study by
means of Erasmus – Socrates mobility/programmes, foreign professors, participants in
various courses, symposiums or colloquia organized by the faculty, etc., are accommodated
in "Gaudeamus" International Exchange Center, which is located in "Codrescu" Student
Hostel Complex.
118
The Library of the Faculty of Biology is one of the branches of “Mihai Eminescu”
Central University Library, it is located within “Alexandru Ioan Cuza” University of Iasi, in
Building B, 1st floor, and it was founded in February 1953, by the name of Natural Sciences
Library, by the fusion of the libraries of Botanyal, biology, morphology, animal and vegetal
physiology laboratories, having a total number of 61 512 publications.
The library of our faculty is currently individualized by:
- total number of volumes purchased during the last 5 years: 1201 books + 1648
periodicals = 2849 volumes;
- total number of places made available for users: 80;
- total area of the library: 456 m2, distributed as follows:
o
publication storing rooms: one storing room for books and two rooms for
periodicals;
o
reading rooms: one reading room for students, with 70 places available and a
reading room for professors, with 10 available places;
o
available storing rooms: one storing room for books; two storing rooms for
serials; two available offices; two halls; one catalogue room; one toilet.
II.9.1. Presentation of the library fund
a. Book fund:
- total number of titles: 17,293;
- number of textbooks and lectures: 3200;
- specialized textbooks (98): biology; ecology; biochemistry;
- atlases: 532 volumes;
- specific dictionaries (466 vol.) and encyclopedias (188 vol.):
- monographs and specialized treaties (615 vol.);
- guides (572 vol.);
- albums (23 vol.).
b. Old book:
- procurement form: donations and purchase; total number of volumes: 235;
- the oldest publication is from year 1836: Bryologia Europaea seu Genera Museorum
europaeorum: Vol. 1;
- origin countries: Romania, France, Germany, Russia, Italy.
c. Periodicals:
- Total number of volumes: 28,558 of link volumes;
- Total number of titles: 1941;
- Covered publications scopes: biology, ecology, agronomy geology, geography,
astronomy, chemistry-physics, biophysics, animal breeding, Botany, pharmacology, etc.;
- Significant titles (the starting year of the periodical included in the library fund is
mentioned):
“Flora oder Botanische Zeitung Welche Recensionen Abhandlungen,
Aufsatze, Neuigkeiten und Nachrichten die Botanik betreffend enthalt”, Resensburg: 1818;
“Annales des Sciences Naturelles. Botanique”, Paris, Crochard&Ce: 1839;
“Revue Generale de Botanique”, Paris, Gaston Bonnier: 1890.
II.9.1. Library computerization and the on-line database
a. Computers of the branch / parameters:
1. User profiles: BIB-BCU\Administrator; BIB-BCU\biology
Computer: X86 Family 6 Model 8 Stepping 3; AT/AT COMPATIBLE; 64 KB RAM
ACPI Uniprocessor PC
Unit: Compaq 10GB 64MB Model No. PM VT DT
Barcode reader: CE 1021G SA1T24004225
Display adapters: Intel® 82815 Graphics Controller
DVD/CD-Rom: E-IDE CD-ROM 48x/TKU
FDD: standard
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Keyboards: Compaq Standard 101/102 key; PS/2 Keyboard (Compaq)
Mouse: Compaq C/T. F!3490N5BI6A2LS; Monitor: Compaq V500
Network Adapter: Realtek RTL 8139(A) PCI FastEthernet Adapter
2. User profiles: BCU-BIO\ Administrator; BCU-BIO\biology
Computer: x86 Family 6 Model 8 Stepping 3; T/AT COMPATIBLE; 64 KB RAM
Unitate: CEL600 10GB 64MB Model No. PM VT DT
Barcode reader: CIPHER LabCE 1021PLUS CP062401744
DVD/CD-ROM : LITEON CD-ROM LTN83L
FDD.: 48X Max 3 ½ inch
Keyboards: PC/AT Enhanced Keyboard (101/102 – key)
Mouse: Logitech PS/2 Port Mouse
Monitor: Z-Vision 15 HR
Network Adapter: Accton EN1207D Series PCI FastEthernet Adapter
Printer: Epson LX-1050+ Model P10SA
Unit: CEL600 10GB 64MB Model No. PM VT DT
b. Database used for publication registration:
At the beginning of year 1999, the Central University Library from Iasi implements the
integrated library system ExLibris Aleph (Automated Library Expandable Program). Version
505.14.2 is currently used, and its platform is a Unix system and a database of the Oracle
8.0 type. The Aleph system is made of 8 flexible modules (OPAC, Cataloguing, Items,
Serials, Acquisition, Circulation, Administration and Alef Administration). In Central University
Library from Iasi, the registered information is managed by means of two databases:
- BCU 01 bibliographic base which includes the bibliographic registrations of the
documents included in the Cataloguing module;
- BCU 50 administrative base which contains the information coming from the
modules of Items, Acquisition, Circulation and Serial Control.
c. On-line catalogue:
Our library provides the beneficiary with the database of its publications, books and
serials (a database that is integrated in the bibliographic database of the Central University
Library from Iasi).
This database may be accessed by means of the on-line catalogue on the Internet,
by the web-page of the library: www.bcu-iasi.ro, where you must click on the “On-line
catalogue” button. The access to the information included in the on-line catalogue of the
library is free of charge (the “Visitor” button) and it is available anytime and from any place
with access to the Internet. The news is that the traditional library cards have been scanned
and introduced in the database o the library this year with information that could not be found
before 2008 in the on-line catalogue. Since 2004, the Central University Library (BCU) from
Iasi is included in a library consortium (BCU Bucharest, BCU Cluj, BCU Iasi and BCU
Timisoara), which has subscribed to a database consisting in other several databases. This
database includes periodical articles, their full-text or summary. The Biology Library, as a
subsidiary of BCU Iasi, provides its users with this new database, which may be accessed
free of charge only from the network of the Central Library and its Subsidiaries; therefore,
there is a need of a public computer which may provide access both to the database of the
Library and to the databases PRO-QUEST, RoLinest, SpringerLink, Ebsco, Scopus, Elsevier,
Emerald, Sage and Embase.
“Professor Ioan Borcea PhD” Marine Biological Station Agigea (Constanta
County)
Manager: Reader Professor Victor Surugiu Ph D
Tel.: +40-241-742940
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“Professor Ioan Borcea Ph D” Marine Biological Station is located at approximately 11
km south from the city of Constanta and 3 km north from the town of Eforie Nord; from an
administrative point-of-view, it belongs to the commune of Agigea, Constanta County. The
station has a total area of 15.1539 ha. The access to the station is provided by the national
road DN 39 (E87) Constanta-Mangalia, either by a lateral road though Agigea commune, or
by the road bridge to the ferryboat terminal Ro-Ro, right before entering Eforie Nord.
The station was founded in 1926 by the eminent zoologist Professor Ioan Borcea Ph
D, and it was the first marine research station on the Romanian shore of the Black Sea.
When Professor Ioan Borcea chose the appropriate place for the station, he considered the
variety of the benthonic and terrestrial biocenoses. The station has gradually developed and
turned into the most famous school for the Romanian hydrobiology. Prestigious specialists
worked in this station, such as Academician Constantin Motas, Academician Eugen
Macovschi, Academician Mihai Bacescu, Academician Petre Jitariu, Academician Eugen
Pora, Academician Olga Necrasov, Professor Sergiu Carausu, Professor Nicolae Gavrilescu,
PhD Maria Celan, etc. Six national and international scientific manifestations have been
organized aqt the Station from Agigea so far (in 1956, 1966, 1969, 1996, 2001 and 2006).
“Professor Ioan Borcea Ph D” Marine Biological Station from Agigea includes the
protected area “Reservation of marine dune plants from Agigea”, which is the only
reservation of this type from Romania and Europe. This reservation gathers rare and very
rare plants, such as the endemic species Alyssum borzeanum, Ephedra distachya or
Convolvulus persicus. Marine dunes have been formed by the deposition of the sand brought
by the wind from an old marine bay situated at north, where there is a part of the old lake
Agigea. Nowadays, the reservation is in the custody of the station according to the Custody
Convention no. 11, based on the provisions of the Government Emergency Ordinance no.
236/2000 on the status of natural protected area, natural habitats and species of wild flora
and fauna conservation, approved with modifications by Law no. 462/2001. The current area
of the reservation is of 6600 m2 and it gathers more than 346 species of vascular plants and
8 moss species. The north Dobrogean turtle (Testudo graeca ibera) is one of the animals
that are protected by law in the reservation. A project was elaborated in 2007 for better
management of the protected area “Reservation of marine dune plants”. The specialists from
the Faculty of Biology within “Alexandru Ioan Cuza” University of Iasi secure a permanent
monitoring and a periodical inventory of the flora and fauna existing in the reservation.
The station has three buildings, where there are the research laboratories and the
dormitories for students, professors and researchers, having a total capacity of 110 places. A
canteen is open in the summer, and it may provide meals for approximately 150 people.
The location of the station near the Danube-Black Sea Channel and near Constanta
Sud-Agigea sea port presents the advantage of an interdisciplinary research approach,
aiming at an anthropic impact on the biodiversity of marine and sweet-water ecosystems, the
elaboration of methods that may evaluate the quality of the marine environment, as well as
prevent and remove the effects of pollution and euthrophysation. 15 research contracts have
been accomplished at Agigea Station between 1990 and 2008.
The Marine Biological Station from Agigea has the following experimenting facilities in
order to develop its researching activities:
- Marine benthos laboratory, focused especially on the systematic, bionomic and
ecological study of benthonic marine invertebrates;
- University-degree laboratory, for students attending the courses of the 1st and 2nd
cycles, who perform research activities in order to elaborate their university-degree and
dissertation theses in the field of biology and the Black Sea ecology; the laboratory is equally
focused on the study of terrestrial and aquatic ecosystems from the Romanian shore of the
Black Sea and Dobrogea;
- Laboratory for students’ practical training, focused on processing the material
collected during the summer practical training activities;
121
- Specialized library, which currently contains more than 3000 volumes and specialized
periodicals, and which exchanges scientific magazines with more than 25 similar institutions
abroad;
- Station museum, which contains a collection of vertebrates from Dobrogea, fishes
and invertebrates from the Black Sea, a collection of macrophyte algae, and a herbarium
with plants that are characteristic to the natural reservations from Dobrogea.
Every year, the station hosts the summer practical training activity performed by the
students from the Faculty of Biology and the Faculty of Geography-Geology within
“Alexandru Ioan Cuza” University of Iasi, from the University of Bucharest, Western
University of Timisoara, “Babes-Bolyai” University of Cluj, University of Bacau, “Ovidius”
University of Constanta, “Dunarea de Jos” University of Galati, “Stefan cel Mare” University
of Suceava, University of Sibiu, University of Pitesti, etc. 44 university-degree theses, 14
dissertation theses and 4 doctor’s degree theses have been elaborated at the Marine
Biological Station from Agigea so far. Moreover, the Station of Agigea has hosted the
summer practical training activities and university-degree theses of students from the Public
University from the Republic of Moldova, the University of Tiraspol, University of Vigo,
Western Catholic University of Angers, etc.
The station is open all year long for students and researchers monitoring certain
aspects of marine and terrestrial ecosystems. Student camps, summer courses, creation
camps, workshops and other educational-cultural activities may be organized at Agigea
throughout the year based on the existing applications.
“Petre Jitariu” Biological Station from Piatra Neamt (Neamt County)
Manager: Professor Costica Misaila Ph D
Tel. +40-232-201522
“Petre Jitariu” Biological Station from Piatra Neamt (Neamt County) includes:
-
Laboratory of Aquaculture and Aquatic Ecology from Piatra Neamt (Neamt
County);
- Laboratory of Aquaculture and Aquatic Ecology from Potoci (Neamt County).
The Laboratory of Aquaculture and Aquatic Ecology from Piatra Neamt, 2 Aleea
Migdalilor; Tel. 0233/218645; Head of Laboratory CP II PhD Nicolae APETROAIE, and
the Laboratory of Aquaculture and Aquatic Ecology from Potoci, Neamt County (on the
shore of Bicaz Lake - Izvorul Muntelui); Tel. 0233/253248; Head of Laboratory Professor
Ionel Miron Ph D.
The Laboratory of Aquaculture and Aquatic Ecology from Piatra Neamt and the
Laboratory of Aquaculture and Aquatic Ecology from Potoci originate in “Stejarul” Station of
Biological Geological and Geographic Research from Pangarati, a station that belongs to “Al.
I. Cuza” University of Iasi. The station was founded in 1957 by the academician Petre Jitariu
from the Faculty of Biology from Iasi, having the following objectives:
- outlining the complex ecological, economic and social processes generated by the
hydro-energetic arrangements on Bistrita river (formation of Bicaz - Izvorul Muntelui
dam lake and of all the accumulation lakes on this river);
- research of genetics and for the improvement of certain medicinal herbs;
- underlay and biological fight against certain vermin that attack plants of economic
importance;
- ornitofauna research;
- pedologic, geomorphologic, climatologic and hydrologic research;
122
-
-
geologic and geochemical research;
supplying the material, didactic and scientific equipment that is necessary for the
practical training development of students from the Faculties of Biology, GeographyGeology within “Al. I. Cuza” University of Iasi, and from other faculties of Biology from
the country and abroad;
supplying the necessary infrastructure for the elaboration of Doctor’s Degree Theses,
Dissertation Theses, University-Degree Projects, and for the 1st teaching degree in
pre-university educational system.
“Petre Jitariu” Biological Station from Neamt currently belongs to “Al. I. Cuza”
University of Iasi, and it is scientifically coordinated by the Faculty of Biology; it has two basic
missions:
- the didactic-scientific activity regarding the supply of practical training conditions for
the students of the Faculties of Biology, Geography and Geology of our University, as
well as for the students attending similar faculties at other Universities from the
country and abroad. The Station area is adapted to the requirements of students’
practical training, as it has 80 accommodation places, canteen, library, laboratories,
working offices, a lecture room with 108 places, etc.;
- research activity within various research contracts and grants in fields of Hydrobiology
(algology, aquaculture, microbiology aquatics, hydrochemistry, sediment chemism,
etc.), application and utilization of sub-aquatic means with submerse laboratory.
Moreover, this is the place of development for certain experiments and observations
that are necessary for Unviersity-Degree, Dissertation and Doctor’s Degree Theses.
Aquaculture and aquatic ecology Research Station from Iasi
Economic Manager: Economist Cornelia Medeleanu
Scientific Manager: CP II PhD Elena Rada Misaila
Tel. +40-232-222513
The Aquaculture and Aquatic Ecology Research Station from Iasi is located in the
southern part of Iasi City, in the area of the Heavy Equipment Plant, on Iasi – Ciurea road,
downstream Iezareni accumulation dam. Founded in 1961, the Fish Research Station from
Podu Iloaiei is the oldest specialized unit in Moldova, and it has this location since 1985. The
station has a total area of 10.7 ha; it includes buildings, interior access ways, dams, and 5.2
ha of water. Moreover, the staff of the station manages, from a fishy perspective, Iezareni
accumulation lake, which has an area of 50 ha.
The Aquaculture and Aquatic Ecology Research Station from Iasi provides the
necessary infrastructure for the development of specific practical activities in the field
of aquaculture and aquatic ecology, for the development of research activities within
various research grants and programmes, for the accomplishment of scientific studies
in view of the elaboration of university-degree, dissertation and doctor’s degree
theses.
“Anastasie Fatu” Botanyal Garden of Iasi
Manager: Professor Catalin Tanase Ph D
Address: 7-9 Dumbrava Rosie Str.
Tel.: +40-232-201373; +40-232-201385
http://Botanya.uaic.ro
123
This representative institution of Iasi City was founded in 1856, and it was the first
university Botanyal Garden of Romania. In time, the Garden has had several locations, and,
in 1963, it was moved on Copou hill, at west of “Expozitiei” Park. The allotted area was of 65
ha at first, and it currently reaches an approximate area of 100 ha; therefore, the Garden of
Iasi is the biggest in the country.
Plantations followed a modern technique on its current location, in order to fulfill the
following functions: didactic, scientific, recreational-cultural and hygienic-sanitary functions.
The scientific thematic of the current Botanyal garden is developed in 12 sections, where
8000 taxa are currently cultivated from all the bio-geographic regions of the world and from
Romania. The activity performed in these departments is accomplished in collaboration with
the Herbarium, Museum and Library of the Garden, and it is supported by the Laboratory of
micro-propagation and preservation of germoplasm, Laboratory for international seed
exchange, Computer Science Laboratory and the Administrative Office.
Taxonomic Section
It is located near the main entrance into the Garden, and it occupies an area of 5 ha.
Approximately 2,000 herbal and wooden taxa are cultivated in this department. The central
axis of the section is marked by two alleys guarded by Thuja occidentalis 'Fastigiata', which
limit a wide ground floor, decorated with Buxus. Around the ground floor, there are various
representatives of the Gymnospermae phylum, casting their shadow on species belonging to
the Pteridophyta phylum. The Gymnospermae phylum is represented by two types of
Metasequoia gliptostroboides (Taxodiaceae family), a collection of species included in the
Pinus genus and several types of Ginkgo biloba. We should also mention the relictary species
of Ephedra distachya. The Angiospermatophyta phylum occupies most part of the section.
Less evaluated representatives of Angiospermae are grouped at the center, around a basin of
aquatic plants and an Auditorium. Several lawns fetch away from this central point in a radial
manner, drawing limits among groups of orders that have evaluated towards the same
direction, creating the following species: Policarpigenae, Rosigenae, Columniferigenae,
Parietaligenae, Centrospermigenae, Liliiflorigenae and Spadiciflorigenae.
Greenhouse Complex Section
The Greenhouse Complex has a total area of 3,800 m2, a shelter for approximately
2,600 taxa, which includes 18 departments, some of them being reserved for scientific
research. Plant collections are grouped based on the geographic origin of plants, taking into
account the ecologic requirements, the plant utility and various esthetic principles.
World Flora Section
This section is located in the North-Western part of the Garden on a total area of 16 ha.
The plants, which are grouped by their place of origin, continents and geographic regions, have
been located using the landscape and mixed styles.
Ornamental Section
It is located at the entry into the Garden, around the administrative premises and the
Greenhouse Complex, and it has an area of 4 ha. Near the Garden entry, there is a ground
floor in the classical style with arabesques of Buxus, rose ribbons and groups of ornamental
graminaceae.
Biologic Section
It is located in the central part of the Garden and it has a total area of 4.5 ha. The
scientific thematic presents certain organization aspects of the vegetal world (structure and
functions), aspects related to plant evolution (evidence and mechanisms), adaptation of
plants to the environmental conditions and man’s role in guiding the evolutionary process.
This section also contains collections of cultivated plants (annual and evergreen), which
124
include the collection of Iris genera; these plants represent a great attraction for visitors in
springtime.
Romanian Flora and Vegetation Section
It occupies an area of 25 ha on the two slopes of Podgoria Copou Valley. The flora
and vegetation are presented by historical provinces and floors of vegetations. Several lakes
have been created by the damming of the Podgoria Copou brook, which provide ecological
environments for water and moor plants. The plants belonging to this Section have been
brought from nature, from the historical provinces that were to be represented.
Dendrologic Section
Having a total area of 20 ha, it is located at the southern extremity of the garden, on the
slope oriented to the West. The collections of trees and bushes have been grouped by genera
and based on the ecologic requirements of the plants. The section has been arranged using
the mixed style, with an inclination towards the landscape style. The section presents a
symmetry axis, which establishes the limit between the sub-sections Gymnospermae and
Angiospermae, facilitating visitors’ circulation.
Rosarium Section
The Rosarium Section is located at the intersection between the main Sections and the
access paths, and it has a total area of 1.55 ha. Roses are grouped based on systematic,
horticultural, genetic and landscaping criteria, observing the chronology of their apparition: in
an evolutionary line, from the spontaneous ones to the last creations of noble genera. Wild
roses and their genera, as well as park and climbing roses occupy the peripheral lawn, near
the coniferous plantations. The noble rose genera are distributed at the center of the area.
Didactic-Experimental Section
In the vicinity of the Rosarium Section, on the south-eastern part of the Garden, there is
the Didactic-Experimental Section, which occupies an area of 4 ha. This section represents a
horticultural and agricultural laboratory, where students, pupils and teachers develop a part of
their practical training and research activity. The structure of this section includes: a) a
selective pomological collection, which is arranged in an intensive tree-culture system; b) a
selective ampelographic collection with various vine genera, which is arranged in an intensive
culture system; c) an experimental field for various experiments performed by the scientific
staff of the Garden and by the professors from the Faculty of Biology.
Useful Plant Section
It has a total area of 1.5 ha and it includes representatives of vegetal resources,
spontaneous and cultivated ones, which are used by man for various purposes. As they walk
through the 9 sub-sections, groups arranged on the land, visitors may be acquainted with and
recognize various plants that are useful or harmful for man: medicinal, toxic, aromatic and
spices, fodders and melifferous, tanning and tinctorial plants, textiles and plants that are used
as sources of cellulose, rubber and resin plants, alimentary and oleaginous plats, as well as
soil fixing plants.
The Memorial Plant Section and the Entertaining Section, which are located in the
northern region of the Garden, are currently being arranged.
Natural History Museum of Iasi
Manager: Reader Professor Ion Cojocaru Ph D
Address: B-dul Independentei nr. 16, 6600 Iasi
125
Tel./fax: +40-232-201339
http://www.bio.uaic.ro/muzeu/muzeu.html
The Natural History Museum of Iasi was founded on 4 February 1834, at the initiative
of a small group of members of the Society of Physicians and Naturalists from Iasi,
coordinated by Iacob Czihac, Gheorghe Asachi, Mihail Zotta, Constantin Sturdza and
Costachi Negri. It is the first museum of this type founded in the Romanian Principalities,
and, as a cultural institution, its purpose was to inform the people of Iasi about the “ground
and underground riches of Moldavia, as well as various curiosities from other parts of the
world.”
The solemn inauguration of the Museum took place on Sunday, at the Bals house, on
Podu Verde alley, nowadays Copou Boulevard. The Museum was sheltered by this house
until 1838, when it was moved to the Great Hall of Mihaileanu Academy.
In 1840, the house of the High Stewart Costachi Sturza was bought for the Museum,
on Hagioaiei Alley, today Independentei Boulevard, no. 16, the building where the Musuem,
and the Society, currently develop their activity too. Article 5 of the House Purchasing Project
stipulates the following: “This house is bought especially for the Cabinet of Natural History or
Museum, a purchase that is for public benefit.”
The Cabinet of Natural History becomes well-known to the public also due to the fact
that, on the night of 3/15 January 1859, in one of its rooms, the Parliament Representatives
of the National Party decided the nomination of Colonel Alexandru Ioan Cuza to the
Moldavian regency. At the historic meeting, due to which the building is subsequently
designated a “Historic Monument”, the group of the 30 Parliament Representatives included
passionate unionists: Mihail Kogalniceanu, Vasile Alecsandri, Constantin Rolla, Nicolae
Docan, Anastasie Panu, Petru Cazimir, Petru Mavrogheni, Dumitru Miclescu, Constantin
Roset Tetcanu, Nicolae Sutu a.s.o.
The collections of the Museum currently include more than 300 000 copies; the most
valuable collections are those of Insects, Mollusks, Amphibians, Reptiles, Birds, Minerals and
Plants.
Collections
In 2000, the inventory of the Museum includes more than 350 000 items; 3,500 of
them are patrimony items, 5,290 are exhibited, and the other ones are stored.
The mollusk collection includes almost all the species of Lamelibranchiate and
Gasteropode of the Romanian fauna. The arachnid (spider) collection is one of the biggest in
the country; it includes specimens from the entire eastern part of the country (Dobrogea,
Moldova and Bucovina).
The biggest insect collections are those of Orthopters, Odonates, Coleopters,
Lepidoptera and Neuropters. Coleopters include more than 50,000 specimens, and the best
represented families are: Staphylinidae, Meloidae, Cerambicidae and Scarabeidae.
The vertebrate collection, which consists of fish, amphibians, reptiles, birds and
mammals, includes more than 14,000 specimens representing almost all the species that
exist in our county; this makes it one of the richest collections in our museums.
The collections of nests and eggs are particularly interesting.
The paleontology collection includes more than 10,000 specimens, while the mineral
collection has more than 2,900 samples.
Plants are arranged in herbariums with species from all over the country, which have
been collected throughout 150 years, while the collection of lichens is one of the richest in
Europe.
Activity
The Museum provides special training programmes, in collaboration with educational
institutions of various levels. These programmes are based on the programme of study at the
126
gymnasium and high school levels, also including practical projects of zoology, agricultural
pests, bio-geography, bio-diversity, nature protection, etc., which are taught at the university
level.
Periodically, to the extent of the available space, temporary exhibitions and
conferences are organized on topics related to: biology, ecology, environment protection.
The specialists of the Museum participate in the research programmes of the Faculty
of Biology focused on topics related to the study of biodiversity.
127
The faculty has an adequate number of rooms for various purposes (laboratories for practical
activities, lecture rooms, research laboratories, library), which are appropriately equipped for
the optimal development of the didactic process and of the research activity.
No.
Building
Floor
Purpose
Room No.
Department
1.
Building B Semi-basement II Laboratory
122a
Biochemistry-Genetics-Microbiology
2.
124
3.
129
4.
Building B
Semi-basement I Laboratory
225
5.
Building B
236
6.
Building B
237
7.
Building B
238a
8.
Building B
239
9.
Building B
240
10. Building B
244
11. Building B
Ground floor
Laboratory
381a
12. Building B
Ground floor
Laboratory
381b
13. Building B
Ground floor
Laboratory
382
14. Building B
Floor I
Laboratory
435
15. Building B
16. Building B
17. Building B
Ground floor
Laboratory
242
Laboratory
344
19. Building B Semi-basement II Laboratory
117
Vegetal biology
20. Building B
18. Building B
224
364
Ground floor
217
Vegetal biology
21. Building B
Floor I
Laboratory
442
Vegetal biology
22. Building B
Floor I
Laboratory
451
Vegetal biology
23. Building B
Floor I
Laboratory
460
Vegetal biology
24. Building B
Floor I
Laboratory
461
Vegetal biology
25. Building B
Floor I
Laboratory
462a
Vegetal biology
26. Building B
Floor I
Laboratory
462c
Vegetal biology
27. Building B
Floor I
Laboratory
463a
Vegetal biology
28. Building B
Floor I
Laboratory
463b
Vegetal biology
29. Building B
Floor I
Laboratory
463c
Vegetal biology
30. Building B
Floor I
Laboratory
464
Vegetal biology
31. Building B
Floor I
Laboratory
465
Vegetal biology
32. Building B
Floor I
Laboratory
466
Vegetal biology
33. Building B
Floor I
Laboratory
467
Vegetal biology
126a
Vegetal biology
107
Animal morphology and physiology
107b
128
108
115
122f
122g
122h
125
127
130a
136
46. Building B
203
47. Building B
204
48. Building B
205
49. Building B
223
50. Building B
234a
51. Building B
234b
52. Building B
226
53. Building B
227
54. Building B
229
55. Building B
245
56. Building B
250
122b
122c
134
Zoology and ecology
135
Zoology and ecology
61. Building B
343
Zoology and ecology
Ground floor
Laboratory
62. Building B
Ground floor
Laboratory
360
Zoology and ecology
63. Building B
Ground floor
Laboratory
361
Zoology and ecology
64. Building B
Ground floor
Laboratory
362
Zoology and ecology
65. Building B
Ground floor
Laboratory
365
Zoology and ecology
66. Building B
Ground floor
Laboratory
373
Zoology and ecology
67. Building B
Ground floor
Inter-Media
375c
Zoology and ecology
68. Building B
Ground floor
Laboratory
376
Zoology and ecology
69. Building B
Ground floor
Laboratory
378
Zoology and ecology
70. Building B
Ground floor
Laboratory
380
Zoology and ecology
71. Building B
Ground floor
Laboratory
341a
Zoology and ecology
126b
Faculty
72. Building B Semi-basement II Photo Laboratory
73. Building B
Semi-basement I Microscopy Laboratory 218
Faculty
74. Building B
Semi-basement I Microscopy Laboratory 219
Faculty
75. Building B
Ground floor
Lecture room
339
76. Building B
Floor I
Library
456
Faculty
Faculty
77. Building B
Floor I
Library
459
Faculty
78. Building B
Floor I
Library
459b
Faculty
79. Building B
Floor I
Library
459c
Faculty
80. Building B
Floor I
Library
459d
Faculty
81. Building B
Floor I
Library
459e
Faculty
129
82. Building B
Floor I
Library
459f
Faculty
83. Building B
Floor I
428
Faculty
84. Building B
Floor I
Dean, Deputy Dean,
Chancellor’s office
Council room
468a
Faculty
85. Building B
Floor I
Dean’s office
468
Faculty
86. Building B
Floor I
Lecture room
B2
Faculty
130
CONTENTS
I. GENERAL INFORMATION ON THE FACULTY
ADDRESS OF THE FACULTY
BRIEF HISTORY
MISSION
SPECIALIZATIONS
FACULTY BOARD
SECRETARIAT
ACADEMIC CALENDAR
4
4
4
5
6
9
11
12
II. ACADEMIC OFFER IN THE MASTER DEGREE SCHOOL
(FACULTY OF BIOLOGY), 2009 - 2011
SPECIALISATIONS - GENERAL PRESENTATION AND CURRICULA
BIODIVERSITY AND PRODUCTIVITY OF ECOSYSTEMS
SHEETS OF THE DISCIPLINES FROM THE CURRICULUM
MOLECULAR GENETICS
MICROBIAL AND CELLS BIOTECHNOLOGIES
BIO-PROCEEDINGS IN AGRO-ALIMENTARY INDUSTRIES
ENVIRONMENTAL CONSULTANCY
14
14
19
35
40
55
60
75
81
95
100
III. FACILITIES PROVIDED TO STUDENTS BY THE
FACULTY
131
117
128

faculty of biology - Universitatea „Alexandru Ioan Cuza”

Transcription

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