medicine summer-2014 - UTHSC News

Transcription

medicine summer-2014 - UTHSC News
T h e U N I V E R S I T Y of T E N N E S S E E H E A L T H S C I E N C E C E N T E R
Campus
Construction
Kicking into High Gear
Page 16
Summer 2014
Loosening the Stranglehold of the
THE UNIVERSITY OF TENNESSEE
HEALTH SCIENCE CENTER
Medicine Magazine
Communications Team
Writing, Editing DAVID MEYER, Editor
and Design TIM BULLARD
Dean’s Message
AMBER CARTER
SHEILA CHAMPLIN
JANE PATE
PEGGY REISSER WINBURNE
News
Art Direction DAVID MEYER
and Illustration
Photography THURMAN HOBSON
Loosening the Stranglehold
of the Stroke Belt
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Additional TIM BULLARD
Alumni
Photography LISA BUSER
SHEILA CHAMPLIN
JANE PATE
BOB SCHATZ
Faculty
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Chancellor STEVE J. SCHWAB, MD
Students
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Vice Chancellor for RANDY L. FARMER, EdD
Development and
Alumni Affairs
Associate Vice Chancellor BETHANY GOOLSBY, JD
for Development
Class Notes & In Memoriam
Shout-Outs
UTHSC in the Media
Associate Vice Chancellor KRISTOPHER PHILLIPS
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Summer 2014
SUMMER 2014
for Alumni
Senior Director of Annual JADA WILLIAMS
Giving/Advancement Services
Director of Development ZACH PRETZER
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The University of Tennessee Medicine magazine is published for
graduates of the Uni­versity of Tennessee College of Medicine. Send all
communications to Alumni Affairs at [email protected] or phone:
(901) 448-5516 or 1 (800) 733-0482 or fax: (901) 448-5906.
www.uthsc.edu
The University of Tennessee does not discriminate on the basis of race, sex, color, religion, national origin, age, disability
or veteran status in provision of educational programs and services or employment opportunities and benefits. This
policy extends to both employment by and admission to the university.
The university does not discriminate on the basis of race, sex, or disability in its educational programs and
activities pursuant to the requirements of Title VI of the Civil Rights Act of 1964, Title IX of the Educational Amendments
of 1972, Section 504 of the Rehabilitation Act of 1973, and the Americans with Disabilities Act (ADA) of 1990.
Inquiries and charges of violation concerning Title VI, Title IX, Section 504, ADA or the Age Discrimination in
Employment Act (ADEA) or any of the other above referenced policies should be directed to the Office of Equity and
Diversity, 910 Madison, Suite 826, Memphis, TN 38163, telephone (901) 448-5558 or TDD (901) 448-7382. Requests for
accommodation of a disability should also be directed to the director of Equity and Diversity, 910 Madison, Suite 826,
Memphis, TN 38163, (901) 448-5558 or TDD (901) 448-7382 or log on to our website at www.uthsc.edu.
E073201(2014-0002wo#1724)
2
Medicine Summer 2014 1
Message From The Executive Dean
Message From The Chancellor
David M. Stern, MD
Steve J. Schwab, MD
W
hen you receive this magazine, UTHSC will have graduated another class
of rigorously prepared medical students, eager to begin their residencies
and delve into clinical practice. The recent reaccreditation of our college
(see page 8) for an eight-year term is a testament to the high quality, intensive medical
education we provide. We are pleased to report that many of the new UT physicians
will undertake the next stage of their careers in the UTHSC statewide system. Under
the auspices of our Graduate Medical Education unit, 68 physicians, 44 percent of our
newly matched residents, will train at our partner hospitals in Memphis, Knoxville and Chattanooga. For photos and
more Match Day statistics, as well as a list of residency placements, see pages 44 to 48.
The college continues to extend our reach, adding accomplished new faculty to expand our range of clinical services as
well as education and research opportunities. We are committed to developing new approaches to address the significant
health disparities and pressing health care needs of our community. On page 14, you’ll read about Dr. Matthew Ballo,
chair of our new Department of Radiation Oncology, which was formed under the joint cancer initiative with UTHSC,
Methodist Le Bonheur Healthcare and the West Cancer Center. Also, beginning on page 19, the feature story on stroke
includes a spotlight on Dr. Andrei Alexandrov, who recently joined us to chair the Department of Neurology. Of course,
you’ll also find several stories in this issue about our extant clinical and discovery-oriented faculty, who continue to earn
significant research awards, publish in prominent industry journals, and share their expertise with colleagues at the start of
their health care journeys.
It’s important to note that, during the February meeting of the UT Board of Trustees, President Joe DiPietro told the
group that expanding research capacities is a challenging area, and UT needs to build on its relationship as co-manager of
Oak Ridge National Laboratory and on corporate partnerships that the UT Health Science Center can develop through
its College of Medicine. On pages 8 and 32, you’ll see evidence of our college’s expanding partnerships with Saint Thomas
Health through accreditation of our residency program, as well as with the West Cancer Center and Methodist as the UT
name becomes part of the logo and brand for the “Fight On!” marketing and outreach campaign.
Another partnership development rapidly coming to fruition is the UT-Regional One Physicians faculty practice,
which is set to launch in the fall. Earlier this year, the Regional Medical Center at Memphis changed its brand and became
Regional One Health. We have been in discussions with Regional One’s leadership for some months about creating a
faculty practice aligned with the hospital. In February, the UT board approved designation of UT-Regional One Physicians
as a faculty practice plan for the College of Medicine in Memphis, authorizing us to move this joint project forward. At
that time, President DiPietro also observed the number of patient billings or clients served by UTHSC has increased
dramatically since FY10. With the creation of another solidly founded, hospital-based faculty practice, we anticipate this
trend will continue.
Despite all the change under way on our campus, on many levels our college remains constant – most especially in our
commitment to educate and train high quality, caring physicians to serve others. We hope you will join us in August for
Medicine Alumni Weekend (schedule of events on page 34) and for the Golden Graduate Homecoming in October (see
page 36 for details). As our alumni, you are a foundational element of our current and future success.
David M. Stern, MD
Executive Dean
College of Medicine
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A
s I write this letter, the footprint of our institution continues to evolve and expand.
On our main campus in Memphis, construction and renovation projects valued at
more than $124 million are either under way or in the planning stages. The new
Translational Science Research Building is on track for completion in 2015, connecting
its researchers via elevated walkways with the scientists in the adjacent Cancer Research
Building. Demolition of Goodman Residence Hall is finished. Following closely on its
heels are razing of the Beale, Randolph and Feurt buildings. (See photos on page 16, and
short demolition videos at www.facebook.com/uthsc, posted on April 4)
Transforming our main campus is a pivotal element in our plan for the future. We are making way for new, state-of-theart research and educational facilities that will reposition UTHSC as the competition intensifies to recruit top-tier students,
researchers and faculty. Revitalizing the Historic Quadrangle as the focal point of our Memphis campus is also on the
horizon, with some $68 million earmarked for this effort.
In tandem with the evolution of our headquarters campus, we are pleased to report that much progress is being made
at our major location in Nashville. Through our deepening partnership with Saint Thomas Health, our reach and impact
in Nashville and Middle Tennessee will increase exponentially. We are laying the foundation for a more vital clinical and
educational presence for our College of Medicine in the central area of the state.
Our College of Pharmacy is also extending its presence in Nashville. In the near future, all of our pharmacy students
will spend their first year of training in Memphis and choose whether to spend their next three years in Nashville, Knoxville
or Memphis. As the needs of our patients rise, statewide and throughout the region, and the demands on our health care
practitioners increase, we continually demonstrate our institution’s flexibility, resolve and dedication to bring health care
education, training and clinical care wherever it is needed.
In February, during the UT Board of Trustees meeting, the board approved the UTHSC Strategic Plan for 2014-2018
with priorities that include:
• Educating outstanding graduates who meet the needs of the state and its communities.
• Growing the research portfolio of the institution focusing on targeted areas.
• Strengthening areas of clinical prominence while expanding outreach.
• Expanding and strengthening key community and statewide partnerships, among others.
Representatives from across our organization have committed to position UTHSC as a national leader in targeted
areas of excellence across the institution’s missions, colleges and campuses by the end of 2018. We are now engaging faculty,
staff, students and administrators in identifying and implementing a variety of initiatives designed to address the strategic
priorities outlined in the plan.
In other action, the board approved renaming the UTHSC College of Allied Health Sciences as the College of Health
Professions, which becomes effective July 1, and approved UTHSC’s acquisition of three neighboring properties in Memphis.
While we all take pride in updated facilities and shiny new buildings, we never lose sight of what truly matters – people
like you, who together with our faculty, staff, students and partners, shape and fuel our organization in the service and care
of those who need our training, compassion and help. Thank you for all you do to contribute to the consistent, forward
movement of our organization. What we are empowered to achieve would not be possible without your generosity and
long-term commitment.
Steve J. Schwab, MD
Chancellor
The UT Health Science Center
Medicine Summer 2014 3
News
HEI
J
Jena J. Steinle, PhD, Named Director
of Research for Hamilton Eye Institute
“In the U.S., our
ability to detect
amyloid deposits
is limited. We’ve
made amazing
progress, but
we need to
move faster.”
Jonathan Wall, PhD
Dr. Jonathan Wall is exploring diagnostic and therapeutic agents for amyloid diseases. Dr. Wall has identified p5, a protein that binds to amyloid
in the brain and other organs, making the amyloid visible through PET imaging and other techniques.
Looking
for Trouble
Dr. Jonathan Wall Gets $1,580,808 Grant
to Improve How We ‘See’ Amyloid
I
t is well known that patients with Alzheimer’s and other disorders, such
as type 2 diabetes, develop amyloid, a substance composed of sticky
protein fibers and sugar molecules that builds up in the brain or other
organs in the body. Doctors do not know whether this material causes
the diseases, or whether the diseases lead to amyloid formation. However,
in less common diseases, such as light chain amyloidosis, a rare but
devastating illness caused by the aggregation of antibody-related light
chain proteins in organs such as the heart, liver, kidneys and spleen, there
is no doubt that amyloid presence in the organs is the cause of the disease.
There is an urgent need to image or “see” the sticky substance in
order to accurately diagnose and determine the stage of the disease and
monitor the therapies used to treat patients. However, in the United States
there are no clinically available methods to image amyloid in patients,
except in those with Alzheimer’s disease. Many patients travel to Europe
for a scan, where the technology is available.
4
Work by UTHSC’s Jonathan Wall, PhD, and his team, is making it
possible to see amyloid deposits, not just in the brain but other organs
of the body.
Dr. Wall, professor in the Graduate School of Medicine and director of
the Preclinical and Diagnostic Molecular Imaging Laboratory in Knoxville,
received a four-year grant totaling $1,580,808 from the National Institute
of Diabetes and Digestive and Kidney Diseases, a subsidiary of the National
Institutes of Health, to study “Preclinical Diagnostic Imaging of Amyloid.”
With the help of his team, including Steven Kennel, PhD; Alan
Stuckey, BA, CNMT; Tina Richey, MS; Sallie Macy, BA; Craig Wooliver,
MLT; Emily Martin, BS; and Angela Williams, MS, Dr. Wall has developed
a series of new imaging agents aimed at advancing the diagnosis and
treatment of patients with amyloid-related diseases.
“In the U.S., our ability to detect amyloid deposits is limited,” Dr. Wall
said. “We’ve made amazing progress, but we need to move faster.”
ena J. Steinle, PhD, associate professor
Dr. Steinle received her
in the Departments of Ophthalmology,
undergraduate degree in biology
Anatomy and Neurobiology, and
from the University of Bridgeport
Pharmaceutical Sciences, has been
in Connecticut, her PhD in
appointed director of research at the
neurophysiology from the University
UTHSC Hamilton Eye Institute (HEI).
of Kansas Medical Center, and did her
Since joining HEI in 2007, Dr. Steinle
postdoctoral work in vascular biology
has been a prolific and successful research
at the Texas A&M University System
scientist. The focus of her research has
Health Science Center.
been on diabetic retinopathy. She has
Dr. Steinle’s writing has appeared
received numerous federal and foundation
in more than 50 peer-reviewed
grants for her work toward developing
publications. She has been awarded
treatments to prevent, or even reverse,
grants from the Department of
damage caused by diabetic retinopathy.
Defense, the Juvenile Diabetes
“Dr. Steinle has a remarkable enthusiasm,” Research Foundation, the National
said James C. Fleming, MD, FACS, chair
Institutes of Health, the Oxnard
of the Department of Ophthalmology at
Foundation, UT Research Foundation
UTHSC. “She infuses our research group
and other organizations.
with energy for innovation, creating a
She is a member of the
vigorous environment for discovery at the
Association for Research in Vision
Hamilton Eye Institute.”
and Ophthalmology, the American
In her new position, Dr. Steinle
Diabetes Association, and Research
directs the Center for Vision Research
to Prevent Blindness. Dr. Steinle is
(CVR), which was established in 1998 as
a medical scientific reviewer for the
a multidisciplinary research program in
National Institutes of Health (ad hoc)
vision science. The CVR is charged with
retina section and a member of the
recognizing, supporting and expanding
complications study section of the
the efforts of individual vision researchers,
Juvenile Diabetes Research Foundation.
and facilitating collaborations. The
“I am excited to have this new
CVR has members, including scientists
opportunity to grow vision research,
and clinicians, from roughly a dozen
both on campus and throughout the
institutions in the community, and has
community,” Dr. Steinle said.
received substantial grant funding to
further vision research.
Jena J. Steinle, PhD
Receives $1.38 Million
Grant for Diabetic
Medication Research
O
ne of the most common side effects of diabetes
is retinal damage. While we know that diabetic
medications are effective in reducing insulin
resistance in humans overall, we do not know their
actions in the retina. The National Eye Institute, a
subsidiary of the National Institutes of Health, has
awarded $1,387,500 to Dr. Jena J. Steinle, who
wants to learn more about how diabetic medication
affects the retina. Dr. Steinle will use the award
to fund her research study titled, “Mechanisms of
TNFalpha-Induced Insulin Resistance in Retinal Cells.”
The study aims to investigate the potential
pathways in the retina that are activated by commonly
used type 2 diabetic medications. Previous work in her
laboratory has shown that these drugs can work to
decrease inflammatory pathways in the retinal blood
vessels, which is protective to the retina. According
to Dr. Steinle, “increased understanding of the actions
in the retina of these commonly used drugs for type
2 diabetes may help us optimize their effectiveness
against diabetic retinopathy, the ocular complication
of both type 1 and type 2 diabetes.”
Medicine
Medicine Summer 2014 5
News
Heartwatch
T
Look AHEAD Study Continues with
$1.6 Million Grant
he Look AHEAD (Action for Health
in Diabetes) Study, funded by the
National Institute of Diabetes and
Digestive and Kidney Diseases (NIDDK),
began in 2001 to examine whether weight
loss and increased physical activity would
prevent cardiovascular events in those with
type 2 diabetes. The study, which produced
several positive results, continues today in
an observational phase.
Karen C. Johnson, MD, MPH, professor
and interim chair of the Department of
Preventive Medicine, one of 16 study centers
for Look AHEAD, has been awarded $1.6
million from the NIDDK to fund the
observational phase of the study here at
UTHSC through 2015.
The clinical trial, which enrolled more
than 5,000 people nationally, showed that
weight loss and increased physical activity
improved many cardiovascular risk factors
for those with diabetes, including blood
pressure, blood sugar and cholesterol.
There were also other benefits, including
reduced depression, better sleep and
improved memory.
However, the NIDDK, a division of the
National Institutes of Health, stopped the
clinical trial in late 2012 when evidence
did not show that the changes prevent
cardiovascular events. NIDDK
continues to fund the study in an
observational phase through 2015,
to follow long-term effects of the
weight loss and physical activity
on the health of participants.
“We know the Look
AHEAD intervention
lowered blood sugar,
we know it lowered
cholesterol, we know
it lowered blood
pressure, and all of
these changes may
ultimately reduce
heart disease.”
Karen C. Johnson, MD, MPH
During the clinical trial, participants
were divided into two groups. One group
received intensive lifestyle intervention,
including individual supervision, group
sessions and diet strategies. The other
received more limited diabetes support and
education. Since the intensive intervention
aspect of the study is over, participants will
come to UTHSC once a
year for measurements,
blood samples, an
EKG, and tests
for physical and
mental function.
“We’re assessing physical function
and cognition in the observational phase,
because we believe that weight loss and
physical activity may improve your physical
function and may improve your cognitive
ability,” Dr. Johnson said. The UTHSC study
includes slightly more than 300 people. “The
data from the trial period does appear like
the intervention group may have reduced
total mortality, but it’s not statistically
significant yet, so we’re continuing to follow
the individuals for that as well.”
Dr. Johnson and co-investigator,
Helmut Steinberg, MD, professor of
endocrinology at UTHSC, hope to extend
this observational phase through 2020.
“We know the Look AHEAD
intervention lowered blood sugar, we know
it lowered cholesterol, we know it lowered
blood pressure, and all of these changes may
ultimately reduce heart disease,” Dr. Johnson
said. “That’s why we think if we follow the
Look AHEAD participants long enough, we
may begin to see some legacy effects.”
Clinical Trials
New Associate Vice Chancellor to Raise
Awareness of UTHSC Clinical Trials Capabilities
David Stern, MD,
hematology/oncology from City of Hope
executive dean
Cancer Center/Harbor-UCLA in Los
“We anticipate he will
of the College of
Angeles. Most recently, Dr. VanderWalde
raise awareness with
Medicine, and
worked for the biopharmaceutical company
external sponsors about
Lawrence Pfeffer,
Amgen, where he served as a Medical
the clinical trial capabilities
PhD, interim vice
Director in Global Development as well as
chancellor for
the U.S. Medical Lead for a pipeline product.
at UTHSC, explore
Research, have
Dr. VanderWalde has extensive
affiliation opportunities
announced Ari
experience in clinical research, including
with our health care
VanderWalde,
the design and conduct of clinical trials,
Ari VanderWalde, MD
MD, MPH,
results
reporting, regulatory filing, and
partners, and facilitate
MBioeth, as the new associate vice
interactions between investigators and the
drug development
chancellor of Research – Clinical Trials.
pharmaceutical industry. He has published
and translation from
Dr. VanderWalde assumed his new
extensively in the field of cancer, as well as
responsibilities in January, reporting to the
in research ethics. Dr. VanderWalde also
UT scientists to
UTHSC vice chancellor for Research and
joins the Department of Medicine, Division
pharmaceutical partners
the chief of Hematology/Oncology.
of Hematology/Oncology, and holds the
and biotech start-up
The position was created to support,
positions of Director of Research with
the West Clinic and Medical Director at
augment and expand clinical trials at UTHSC,
companies.”
ACORN
Research LLC.
which has been engaged in federally funded
Lawrence Pfeffer, PhD, interim
“Among
his many duties, Dr.
clinical trials for more than 60 years. Clinical
vice chancellor for Research
VanderWalde will be responsible for aligning
trials are scientific studies in which new
processes in our various UTHSC colleges
treatments – drugs, diagnostic procedures,
related to pharmaceutical studies, recruiting
therapies or preventive measures – are tested
staff to support strategic research initiatives, plus organizing and
in patients to determine if they are safe and effective.
After obtaining an undergraduate degree at Harvard University, utilizing the infrastructure to support UTHSC clinical research,”
said Dr. Pfeffer. “We anticipate he will raise awareness with
Dr. VanderWalde completed medical school at the University of
external sponsors about the clinical trial capabilities at UTHSC,
Pennsylvania, where he also earned a master’s in Bioethics, while
explore affiliation opportunities with our health care partners, and
simultaneously obtaining a master’s of Public Health from Harvard
facilitate drug development and translation from UT scientists to
School of Public Health. An internship and residency in internal
pharmaceutical partners and biotech start-up companies.”
medicine at UCLA followed. Next, he completed a fellowship in
Karen C. Johnson, MD, MPH
6
Medicine Summer 2014 7
A C C R E D I T A T I O N
8
Saint Thomas Health and UT
Residency Program Accredited
S
aint Thomas Health’s Saint Louise Clinic
in Murfreesboro and the University
of Tennessee College of Medicine
recently announced their partnership to bring
a Family Medicine Residency program to
Middle Tennessee. The program has now
been accredited by the Accreditation Council
for Graduate Medical Education and will
begin training physicians in 2015.
To ensure the proper space for
physician training and patient care, the Saint
Louise Clinic relocated to a larger facility. The
clinic, now called the University of Tennessee
Family Medicine Center and Saint Louise
Clinic, allows Saint Thomas Health to better
serve the Rutherford population, as well as
host the UT Family Medicine Program.
The partnership between UT and
Saint Thomas Health creates expanded
capabilities to meet patient needs. For
example, the Family Medicine Residency
Program allows the clinic to have more
medical providers on staff. With four
full-time faculty, 24 residents, nurse
practitioners, physician assistants, and
18 exam rooms, the clinic can provide
more care to more patients.
“With the newly accredited residency
program, we can move forward with our
mission to provide better health care to
communities in Rutherford County,” said
­­­Christopher Dunlap, MD, director of the
Family Medicine Residency Program at the
Saint Louise Clinic.
UTHSC College of Medicine Reaccredited
T
he Liaison Committee on Medical Education (LCME)
has reaccredited the University of Tennessee College of
Medicine for the maximum eight-year term. The college
received the official letter detailing this decision on March 11, 2014.
The LCME accredits all allopathic medical schools
in the United States and Canada. Accreditation
signifies that national standards for structure,
function and performance are met by a
medical school’s education program.
Only LCME-accredited institutions
may receive federal grants for
medical education and participate
in federal loan programs. U.S.
medical students must be
enrolled in, or graduated from,
an LCME-accredited program
before they can take national
board exams (U.S. Medical
Licensing Exam) or enter
residency programs.
The preparations for the
accreditation process took
nearly two years and included
an extensive self-study that
involved more than 100 faculty,
administrators and students. The medical students also conducted
an independent self-study that was submitted to the LCME. A fivemember survey team comprised of faculty and administrators from
other medical schools spent three days on campus in November
reviewing the documentation and meeting with
approximately 150 faculty and students. The
survey team’s extensive report was reviewed
by the LCME at its February meeting.
Of the approximately 135
standards, the College of
Medicine was only judged to be
noncompliant with five standards,
with four others noted as in
compliance, but in need of
monitoring. This is slightly
better than the average
number of citations schools
have received in the past
three years. The school must
submit an update on areas
of citation by April 2015, but
there will not be a second
site visit — something many
schools are experiencing two
years after the initial visit.
Learning How to Fight a Killer
W O M E N ’ S H E A L T H
News
Searching for New Therapies for Triple-Negative Breast Cancer
B
The American Cancer Society has awarded
$720,000 to Dr. Zhaohui Wu to continue
his studies of treatment options for triplenegative breast cancer.
reast cancer is a leading cause of cancer- “Role of Genotoxic NF-kB Activation in Breast
related deaths in women worldwide, and
Cancer Metastasis.”
those diagnosed with triple-negative
Previous studies conducted by Dr. Wu
breast cancer (TNBC), an aggressive breast
and his research team have indicated that the
cancer subtype, have a lower survival rate than activation of a transcription factor or protein
other breast cancer patients.
known as NF-kB by chemotherapeutic drugs
The higher death rate is partially due to a
may promote cancer therapy resistance and
lack of effective targeted therapy. Chemotherapy metastasis. His team is working to determine
is the only available systemic treatment for
the factors responsible for that resistance. The
TNBC. However, many TNBC patients rapidly
research team is also exploring therapeutic
develop resistance to the treatments. They
regimens to effectively restore sensitivity of
also develop aggressive metastasis, which
the breast cancer cells to chemotherapies and
is responsible for the majority of the deaths
reduce secondary tumors.
caused by the cancer. Zhaohui Wu, MD, PhD,
“I am truly honored and grateful to receive
is exploring other options that could lead to a
this Research Scholar Award from the American
breakthrough in treatment.
Cancer Society,” said Dr. Wu. “This grant support
Dr. Wu, an assistant professor in the
allows us to further extend our exploration of novel
Department of Pathology and Laboratory
molecular mechanisms involved in therapeutic
Medicine, is now being supported by a
resistance in breast cancer patients. We expect
$720,000 Research Scholar Grant from the
our study will translate into effective therapeutic
American Cancer Society to fund his study titled,
regimens for treating breast cancer in the future.”
Dr. Nikki Zite Recommends Reproductive Rights
Changes in New England Journal of Medicine
T
he New England Journal of
Medicine published a perspectives
piece in its Jan. 9 issue co-authored
by Nikki Zite, MD, associate professor
and residency program director in
Obstetrics and Gynecology at the UT
Graduate School of Medicine (UTGSM)
in Knoxville. Dr. Zite’s topic was research
on women’s access to sterilization based on
current Medicaid policy and whether that
policy is still relevant.
Current policy, established in the
1970s, prohibits persons younger than
21 years old from being sterilized as well
as those who are mentally incompetent
or institutionalized. The focus of the
perspectives piece was related to the
mandatory 30-day waiting period from the
date of written informed consent that is
required. In addition, a signed copy of the
consent form must be available or verified
at the time of the procedure. The only
exception is if the patient is undergoing
emergency abdominal surgery or a
premature delivery. Then the 30-day waiting
her collaborators, some of which was
completed in the University of Tennessee
OB/GYN clinic indicates the consent
process may not be capable of protecting
vulnerable women by ensuring that truly
informed consent is obtained. A previous
study by Dr. Zite on the comprehension
of women who sign the consent form
for tubal sterilization shows the form
is written at a reading level too difficult
for most patients to understand. Beyond
concerns about the consent form, the
waiting period and the need for the
completed form to be transferred to
the delivery unit pose logistic barriers
for women who wish to undergo tubal
ligation immediately after giving birth.
The authors of the perspectives piece
recommend that the Medicaid policy and
Nikki Zite, MD
consent form concerning sterilization
period may be waived if there is 72 hours should be thoughtfully modified.
between signed consent and the procedure.
James Neutens, PhD, dean of
The Medicaid policy was originally
the UTGSM, noted, “This is a great
established to protect minority women’s contribution to the diversity and inclusion
rights, however research by Dr. Zite and efforts being made in health care today.”
Medicine Summer 2014 9
News
a Commitment to
Approximately one-third of the world’s population is infected with tuberculosis (TB0,an infectious disease that is often contracted through an
airborne bacterium known as Mycobacterium tuberculosis. Globally, at least one person is infected each second, and someone dies of the disease
every 20 seconds. TB remains a leading public health problem worldwide, with an estimated 8 million new cases and 2 million deaths each year.
T U B E R C U L O S I S
F I N D I N G
I T .
F I G H T I N G
I T .
Assistant Professor Ying Kong Receives Grant
Y
ing Kong, PhD, an assistant professor in the Department of Microbiology,
Immunology and Biochemistry at the UTHSC College of Medicine, received a
grant totaling $187,343 from the National Heart, Lung, and Blood Institute, a
subsidiary of the National Institutes of Health, to explore the pathogenesis or the origin and
development of extrapulmonary TB. Known as an R21 grant, the award encourages new,
exploratory and developmental research projects by providing support for the early stages
of project development. Dr. Kong’s study is titled, “Non-invasive Fluorescent Imaging
Mycobacterium Tuberculosis Extrapulmonary Infection.”
Although most M. tuberculosis infections, known as pulmonary TB, are in the
lungs, five to 10 percent of TB patients can develop the disease in organs other than
their lungs, or extrapulmonary TB. Dr. Kong is exploring the pathogenesis or the origin
and development of the latter. Extrapulmonary sites of infection can involve almost any
organ, such as lymph nodes, bones and joints, eyes, intestines, larynx, or the urinary and
reproductive systems, skin and stomach. This condition is difficult to diagnose because
the clinical presentation is atypical; tissue samples for the confirmation of diagnosis
can sometimes be difficult to procure; and the conventional diagnostic methods have
a poor yield, often resulting in delayed diagnosis. Better understanding of the disease’s
pathogenesis is urgently required to control it.
“With the grant, we will evaluate two imaging compounds for in vivo imaging of M.
tuberculosis infection in rodents,” said Dr. Kong. “The compound with higher sensitivity
for detecting bacteria will be selected to study the aspects of bacterial invasion and
dissemination from the initial pulmonary infection site (to other organs) in rodents. The
success of this study will help to unravel the intricacies of extrapulmonary TB and to
screen for anti-TB therapies and vaccines in live animals.”
Dr. Kennard Brown Honored for Promoting
Diversity in Health Care Education
Kennard Brown, JD, MPA, PhD, FACHE, executive vice chancellor and chief
operating officer of the UTHSC, has received the Healthcare Education Award from
the Nashville-based Council on Workforce Innovation.
The statewide award, presented at the recent 2014 Healthcare Diversity Forum
in Nashville, recognized Dr. Brown’s efforts in promoting diversity in health care
education. The regional forum, which drew administrators, clinicians, educators,
human resource specialists and business leaders, focused on the financial value of
diversity in the health care workforce and discussed resources for advancing quality
health care delivery for underrepresented populations.
The Council on Workforce Innovation is part of the National Organization
for Workforce Diversity, a private, public and non-profit coalition to promote
workforce diversity initiatives.
Dr. Brown has been with UTHSC for 15 years. He started in the Office of
General Counsel, and has directed several UTHSC offices, including Equity and
Diversity, Employee Relations and the Center on Health Disparities.
Dr. Kennard Brown (right), is congratulated by State Rep. G. A. Hardaway, D-Memphis, for receiving
the Health Care Education Award from the Council on Workforce Innovation in Nashville.
With his new funding, Dr. Ying Kong will delve deeper into his studies
of tuberculosis, primarily focusing on host-pathogen interactions.
Dr. Bernd Meibohm’s Findings Published
in Nature Medicine Journal
B
ernd Meibohm, PhD, FCP, associate dean for
Research and Graduate Programs and professor in
the Department of Pharmaceutical Sciences, had the
findings of his latest research published in the February issue of
Nature Medicine, a leading journal for the biomedical sciences.
The article, titled “Spectinamides: a new class of
semisynthetic antituberculosis agents that overcome native
drug efflux,” discussed significant breakthroughs
in tuberculosis research.
Dr. Meibohm’s research is significant not only because
of the rapid rise of multi-drug resistant tuberculosis (1.4
million die of the disease every year), but also because
the pharmaceutical industry has largely abandoned the
development of new antibiotics, leaving drug discovery
in this area to academia and nonprofit organizations.
The published research is a collaborative effort of Dr.
Meibohm’s research team and investigators Richard Lee, PhD,
at St. Jude Children’s Research Hospital; Anne Lenaerts, PhD,
at Colorado State University; and Erik Böttger, MD, at the
University of Zurich.
10
On Jan. 28, (from left) Larry E. Kun, MD, Clinical Director and EVP at St. Jude Children’s Research Hospital; Governor Bill Haslam; Jon McCullers, MD, chair of the
Department of Pediatrics for UTHSC and pediatrician-in-chief for Le Bonheur Children’s Hospital; and Maureen O’Connor, director of Policy at Le Bonheur Children’s
Hospital, met to discuss how funding commitments from the legislature in 2013 have helped to move pediatric research forward.
In 2013, the legislature committed $15 million over five years from the state of Tennessee to support pediatric research at UTHSC, which matches the same financial
commitment by St. Jude to support the UT Department of Pediatrics. The funds are helping to recruit physician-scientists to and retain pediatric researchers at the
state’s only public, academic health science center — UTHSC.
The results of collaborative research efforts by Dr. Bernd Meibohm (right), his research team,
Dora Madhura, PhD, (center), and Ashit Trivedi, MS, as well as investigators at other institutions,
were published in the February issue of Nature Medicine, a leading biomedical sciences journal.
Background: Photomicrograph of a sputum sample containing Mycobacterium tuberculosis
In addition to talking with Gov. Haslam, Dr. McCullers, Dr. Kun and O’Connor met with the governor’s Chief of Staff Mark Cate, Commissioner of Finance Larry Martin, and
had lunch with Lt. Governor Ron Ramsey. They later spent time with House Speaker Beth Harwell, Senate Majority Leader Mark Norris, Tennessee Department of Health
Commissioner John Dreyzehner, Senate Finance Chairman Randy McNally, Senate Health Chairman Rusty Crowe and House Health Chairman Bob Ramsey. Dr. McCullers
also had the opportunity to update the House Finance, Ways and Means Committee on how the state funds are being used.
Medicine
Medicine Summer 2014 11
News
‘Reflect
&
Remember’
Dr. Alvin Crawford Brings
D
Inspiration Home to UTHSC
r. Alvin Crawford, MD, FACS, the first African-American student to be admitted to
and graduate from the UTHSC College of Medicine, returned to his alma mater as
guest speaker at the “Reflect & Remember” lunch session in April. Dr. Crawford took
the opportunity to remember Dr. Martin Luther King, Jr., and talk to students about his legacy.
Dr. Crawford, who graduated from UTHSC in 1964, is professor emeritus of Pediatrics
and Orthopaedic Surgery at the University of Cincinnati College of Medicine. He is also a
graduate of Melrose High School, and took time to visit with the students there and
at Frayser High to stress the importance of achieving their dreams.
You can find out more about Dr. Crawford in a video from the
Cincinnati USA Regional Chamber: http://bit.ly/1iCbpfF
Dr. GomesSolecki and
US Biologic
“M
Recognized in
U.S. House of
Representatives
The work of Maria Gomes-Solecki, DVM, and US Biologic was recognized in December
by U.S. Representative Steve Cohen. Dr. Gomes-Solecki is an assistant professor in the
Department of Microbiology, Immunology and Biochemistry at UTHSC. She co-founded
US Biologic in 2012 with four Memphis-based entrepreneurs.
r. Speaker, today I would like to recognize the work of Memphis-based US
Biologic in their work to halt the spread of Lyme disease. US Biologic was
recently awarded a grant of $1 million from the Global Food and Health
Innovation Challenge to expand their research on this important topic, and I am proud to
honor the hard work of their dedicated research team, especially Maria Gomes-Solecki.
“I believe that our nation’s true department of defense is made up of doctors and
researchers who work hard to find cures and prevention methods for the diseases that
threaten the lives and livelihoods of Americans every day. The research of people like
Dr. Gomes-Solecki is integral in our mission to make the United States a safer place
for the grandchildren of our generation, and I encourage more federal investment in
the initiatives of the National Institutes of Health, as well as private funding like that
provided through the Global Food and Health Innovation Challenge.
“I congratulate US Biologic and Dr. Gomes-Solecki on their achievement and
I look forward to more developments from some of the nation’s most advanced
researchers who are based in my district.”
Hon. Steve Cohen of Tennessee in the United States House of Representatives, Dec. 2, 2013
Auction of Works by Artist Paul Penczner
Grosses More Than $70,000
UT
Day
on the
Hill
12
12
A
(left to right) Porshia Mahoro from the College of Nursing, Cosby Arnold from the College of Medicine
and Lauren Bode from the College of Pharmacy joined President Joe DiPietro, along with students and
staff from all UT campuses and institutes to represent the university at the annual UT Day on the Hill
held Feb. 18 on the Legislative Plaza in Nashville. Participants staffed informational displays and met with
legislators to spread the word about the UT’s statewide impact on research, education and health care.
n online auction by UTHSC on March 26, of more than 300 works by
internationally known Memphis artist Paul Penczner grossed more
than $70,000.
The sale, which opened for bidding March 4, and finished with a rapid,
rolling auction, drew 158 bidders.
Works auctioned are part of a collection of 400 pieces donated to the UTHSC
College of Medicine by the artist’s widow, Jolanda Penczner, after his death in
2010 to establish an endowment in his name in the Department of Physiology.
Proceeds, minus expenses, will go for cardiovascular research at UTHSC.
“The auction was a huge success,” said Zach Pretzer, director of development for
the UTHSC College of Medicine. “It was a wonderful conclusion to what has been
a tremendous gift to the UT College of Medicine by Paul and Jolanda Penczner.”
Medicine Summer 2014 13
News
Maximizing
Matthew Ballo, MD: Chair of New Department of Radiation Oncology
D
avid Stern, MD, executive dean
of the College of Medicine, has
named Matthew T. Ballo, MD,
chair of the newly formed Department
of Radiation Oncology.
Dr. Ballo, who began his duties at
UTHSC in January, has been a professor
in the Department of Radiation Oncology
at the University of Texas MD Anderson
Cancer Center in Houston. He has also
served as an adjunct assistant professor
of radiation therapy in the Department of
Radiation Oncology at the University of
Texas MD Anderson Cancer Center School
of Health Sciences in Houston.
“The College of Medicine has formed
a new Department of Radiation Oncology,
and in collaboration under the joint cancer
initiative with Methodist Le Bonheur
Healthcare, UT and the West Cancer
Center, we have recruited Dr. Matt Ballo as
the founding chair and chief of Radiation
Oncology in the cancer center,” Dr. Stern
said. “Dr. Ballo is recognized for his expertise
in head and neck radiation oncology, as
well as his vision for designing a radiation
oncology enterprise of tomorrow. In addition
to developing clinical specialization within
radiation oncology, he will promote training
and research programs in medical physics
and radiation oncology, and will be an
integral member of the leadership team of
the West Cancer Center.”
14
“In addition to developing
clinical specialization
within radiation oncology,
he will promote training
and research programs
in medical physics and
radiation oncology, and
will be an integral member
of the leadership team of
the West Cancer Center.”
David Stern, MD, executive
dean of the College of Medicine
Dr. Ballo received his BA in biochemistry in 1991 from Oberlin College in Oberlin, Ohio, and his
MD degree from Case Western Reserve University School of Medicine in Cleveland in 1995. He did his
clinical internship at Mt. Sinai Medical Center in Cleveland, and his clinical residency at the University of
Texas MD Anderson Cancer Center in Houston.
Having published 66 peer-reviewed, original research articles, his work also includes about
three dozen invited articles, editorials, abstracts and book chapters. He is a member of the editorial
review board and guest editor of Breast Diseases: a Yearbook Quarterly. He is a journal reviewer for
publications, including the International Journal of Radiation Oncology, Biology, Physics; International
Journal of Cancer; Radiotherapy & Oncology; The Lancet Oncology; and Head & Neck.
Dr. Ballo is a member of numerous professional organizations, including the American Society
for Therapeutic Radiology and Oncology; the American College of Radiology and the American Society
of Clinical Oncology.
Professor R
Robert Williams
Receives
$2.5 Million
for Genetics
Research
obert W. Williams, PhD, professor in the
Departments of Anatomy and Neurobiology,
and Pediatrics and director of the UT Center
for Integrative and Translational Genomics, is
working to make significant headway on the
genetics of diet and aging, thanks to a new grant.
The award, from the National Institute on Aging,
a subsidiary of the National Institutes of Health
(NIH), totals $2,545,349. It will fund his five-year
study entitled, “Translational Systems Genetics of
Mitochondria, Metabolism, and Aging.”
Dr. Williams and his research team, which includes Karen C. Johnson,
MD, MPH, and Khyobeni Mozhui, PhD, both from the UTHSC Department
of Preventive Medicine, as well as one of the world’s pre-eminent
experts on metabolism, Johan Auwerx, MD, PhD, professor at the Swiss
Federal Institute of Technology in Lausanne, are studying the impact of
high- and low-fat diets on aging and the role of genetic difference on
mitochondrial function as age progresses.
Professor A
Andrew Kang
Receives
$1.65 Million
Grant for
Rheumatoid
Arthritis
Research
ndrew Kang, MD,
professor in the Division
of Connective Tissue
Diseases in the College of
Medicine, has received a grant
totaling $1,650,000 from the
National Institute of Arthritis
and Musculoskeletal and Skin
Diseases, an Institute of the
National Institutes of Health.
The award will be used to
support a project titled “20 (OH)
Vit D3, T Cells, and Arthritis,”
and will be distributed over a
five-year period.
Rheumatoid arthritis is an autoimmune disease of unknown
cause that afflicts approximately one percent of the population
worldwide. While there are several treatments available, they are
helpful for only a portion of those affected, and are associated
with significant side effects.
The goal of Dr. Kang and his research team is to improve
treatment options. His team includes Linda Myers, MD, professor
in the Department of Pediatrics, Arnold Postlethwaite, MD, chief in
the Division of Connective Tissue Diseases and Goodman Chair of
Excellence in the Department of Medicine, and Andrzej Slominski,
MD, PhD, professor in the Department of Pathology at UTHSC.
“We hope to develop an effective but safer treatment involving a
combination of a synthetic peptide originally developed at UTHSC,
as well as a unique form of vitamin D that does not cause elevation
of blood calcium levels to toxic range,” explained Dr. Kang.
The results of this research may lead to a more effective
therapy without the serious side effects that are associated with
the currently available treatments.
Medicine Summer 2014 15
News
Kicking into High Gear: Campus Construction is Changing the Face of the University
M
ajor construction projects are changing
the face of the 103-year-old campus of
UTHSC.
A $49 million Translational Science
Research Building is set for completion in
2015, obsolete buildings are coming down, and
multiple construction and renovation projects
worth more than $175 million are in the
planning stages or under way.
The construction reflects efforts by the
UTHSC administration to raise the profile of the
university and draw top-tier students, faculty and
researchers to Memphis. It also illustrates the
support and willingness of state officials to help
finance improvements to enhance Tennessee’s
only public, statewide, academic health system.
“It’s about the infrastructure, if you want
to attract the best and brightest,” said Kennard
Brown, JD, MPA, PhD, FACHE, executive vice
chancellor and chief operations officer for
UTHSC. “We had to move to that state-of-theart kind of space.”
Commencing the campus facelift, a
90,000-square-foot Cancer Research Building
opened in 2007. The first new building on
campus in 17 years, it cost $25.2 million, and
houses research laboratories that investigate
Bulldozers began taking down
vacant buildings on campus
in March, including the Beale
Building, a former city bus barn
built in 1925.
16
experimental therapeutics, genetics, and
mechanisms related to adult cancer.
Since then, the pace of construction at
UTHSC has picked up dramatically.
In 2011, a new 183,000-square-foot, $57
million building opened to house the College of
Pharmacy, which has been ranked in the top 20
“It’s about the
infrastructure, if you
want to attract the
best and brightest.”
Kennard Brown, JD, MPA,
PhD, FACHE, executive
vice chancellor and chief
operations officer for UTHSC
pharmacy schools in the nation by U.S. News
and World Report for more than a decade.
The 135,000-square-foot Translational
Science Research Building is going up adjacent
to the Cancer Research Building. Nearly a
mirror image of the cancer building, the fourstory Translational Science Research Building
will house investigators from all colleges and
departments doing “bench-to-bedside” work,
or research as it applies to clinical settings.
More than $68 million has been
earmarked for the renovation of buildings
in the Historic Quadrangle at the center of
campus. The Mooney Memorial Library, focal
point of the quadrangle, will be converted
to administrative offices, reception areas
and meeting space. The Nash Research
Building, and the annex that was added in the
1980s, will be renovated for state-of-the-art
research space. A third building bordering
the quadrangle, the Crowe Building, will be
upgraded to house the College of Nursing. The
projects, which are in the planning stages and
expected to take 18 months to three years to
complete, are aimed at “bringing people back
to the quadrangle,” Dr. Brown said.
The Feurt Pharmacy Research Building
will come down to make room for a $24.1
million Multi-Disciplinary Simulation and Health
Education Building, where students from all
six colleges on campus will train together in
cutting-edge simulation settings.
Work on an $11.2 million GMP (Good
Manufacturing Practices) facility for drug
development and manufacturing will begin
later this year in a building purchased on the
outskirts of campus.
Thanks to $4.5 million appropriated by the
state for demolition, bulldozers began taking
down vacant buildings on campus in March.
Two empty housing facilities, the Goodman
Family Residence Hall and Randolph Hall, have
been torn down or are scheduled to be torn
down. Professional students no longer want to
live in dormitory-style housing, Dr. Brown noted.
The Beale Building, a former city bus barn
built in 1925 and given to the university decades
ago, has been leveled for immediate use as parking
space, and later as a possible public-private
residential venture that could attract students.
Renovations of existing buildings include:
finishing the fourth floor of the Cancer
Research Building for additional lab space,
The vacant Goodman Family Residence Hall has
been torn down.
$4.8 million; completing the fifth and sixth
floors of the Pharmacy Building for expanded
research enterprises and office space, $9.5
million; and renovating the medical library in
the Lamar Alexander Building and retrofitting
the early 1980s structure to be more
environmentally friendly, $6.1 million.
Planned but unfunded projects include:
a Women’s and Infants’ Pavilion to provide topquality care and facilities for mothers and babies
to help combat the area’s high infant mortality
rate; acquiring space and erecting a new building
to house the College of Medicine; and adding a
second building for the College of Dentistry.
Reshaping the UTHSC campus is an
important step for the future, Dr. Brown said.
“It will help us maintain the competitive edge.”
Dr. Jon McCullers
Reviews Influenza
and Bacterial
Super-Infections
Le Bonheur Children’s Hospital pediatrician-inchief Jon McCullers, MD, was invited to submit
a review in the April issue of Nature Reviews
Microbiology. McCullers, an infectious disease
specialist and chair of the UTHSC Department
of Pediatrics, analyzed the epidemiology and
microbiology of co-infections during the 1918,
1957 and 1968 pandemics, as well as more
recent 2009 novel H1N1 pandemic.
Dr. McCullers reviewed the co-pathogenesis
of influenza viruses with bacteria in the lung.
Bacterial superinfection in the lungs of those
suffering from influenza is a key element that
promotes severe disease and mortality.
McCullers recommends large-scale studies
involving consortia or clinical networks to unlock
the next unanswered questions about coinfections and viruses in order to prevent the loss
of life in a pandemic similar to the one in 1918.
Professor Jonathan
Jaggar Receives Grant
Supplement for Blood
Pressure Research
Jonathan Jaggar, PhD, the Maury W.
Bronstein Professor in the Department
of Physiology at the UTHSC College of
Medicine, has received a grant totaling
$95,931 from the National Heart, Lung,
and Blood Institute of the National
Institutes of Health. The award, which will
be distributed over a three-year period, is
a supplement to his existing study titled,
“Arterial Smooth Muscle Channels.”
The supplement will allow Dr. Jaggar
and his research team to test the hypothesis
that proteins, called anoctamin 1, located
within the cell membrane of arterial
smooth muscle cells respond to an increase
in blood pressure. If research is successful,
it may eventually lead to the development
of novel therapies and drugs to treat
hypertension and brain disorders that result
from hypertension.
Medicine Summer 2014 17
News
Roughly 50 members of the Memphis bioscience, business and health care communities, plus several state legislators and government agency representatives
joined the Dedication of the Central Green at the UT-Baptist Research Park. Unveiling the plaque that commemorates Baptist’s $100 million gift of land and buildings
were (from left) State Senate Majority Leader Mark Norris, UTHSC Chancellor Steve Schwab, J. R. “Pitt” Hyde, Stephen Reynolds, president and CEO of Baptist
Memorial Health Care (BMHC), who was set to retire a month after this event, Baptist’s incoming President and CEO Jason Little, who was executive vice president
and COO of BMHC when this photo was taken, and Steve Bares, president and executive director, Memphis Bioworks Foundation.
Loosening the Stranglehold of the
Central Green to Grow On
O
grounds: the UTHSC Regional Biocontainment
n Friday, May 9, leaders from the
times and good times. His vision for the
Laboratory, UT College of Pharmacy plus TriMetis, medical center district is the main reason that
Memphis business, bioscience,
a specialized laboratory and research firm.
health care and legislative
we are all here today.
Guests at the Dedication of the Central
communities gathered for the Dedication of the
“In addition, the state of Tennessee has
Central Green at the UT-Baptist Research Park, Green also witnessed the unveiling of the
made major contributions to UTHSC. In recent
Baptist Memorial Hospital-Medical Center
which is adjacent to the UTHSC main campus.
years, more than $130 million has been poured
Commemorative Plaque. In 2002, when Baptist
The event celebrated completion of the fourth
into our institution, funds that were designated
donated four medical office buildings and
phase of development of the research park,
for demolition and funds for building new facilities
1.4 million square feet of land to UTHSC, the
located in the heart of the Memphis Medical
on this campus. One of the centers of the UTHSC
contribution was one of the largest academic
Center. The program included brief remarks
campus is the Madison complex of buildings that
gifts ever in the United States. When completed
from J.R. “Pitt” Hyde, III, chairman of the
were Baptist buildings 15 years ago. Without
the UT-Baptist Research Park is expected to add Baptist’s generous gift, this would not be possible.”
board, Memphis Bioworks Foundation, UTHSC
Chancellor Steve J. Schwab, MD, State Senate 1.2 million square feet of laboratory, research,
Chancellor Schwab also singled out
Majority Leader Mark Norris, Stephen Reynolds, education and business development space on
president and executive director of the Memphis
its 10-acre campus.
president and CEO, Baptist Memorial Health
Bioworks Foundation Steven J. Bares, PhD, for
“It is a pleasure to be here because this
Care, and Jason Little, executive vice president
“the tireless work he does to support UTHSC …
event is an opportunity for the UT Health Science
and COO, Baptist Memorial Health Care.
Bioworks understands that the UT-Baptist
Center to thank our partners for helping us
Being implemented in six phases, UTResearch Park is a cornerstone of our campus –
get where we are today,” Chancellor Schwab
Baptist Research Park is about nine years into
architecturally and in commercializing science.”
said. “UTHSC today is a dramatically rejuvenated
its development plan. Once construction is
“This research park is a key part of the
campus … in the best go-forward position
finished, UT-Baptist Research Park is expected
future growth and success of our community,”
that we’ve been in for a very long time. Here in
to produce a $2 billion annual economic impact
Hyde stated. “I’m thrilled with the progress
Memphis our main campus has experienced
on Memphis with $250 million in annual salaries
and prospects in front of us. And I’m thrilled
a real renaissance. J. R. Pitt Hyde, III, is the
from 5,000 new jobs. Currently there are three
at looking forward to working with you on the
visionary who supported UT through hard
facilities in operation on the research park
continued development of the research park.”
18
I
n the Southeast, we are encircled by so many
belts, it’s a wonder we can breathe. The Stroke
Belt, the Diabetes Belt, the Cancer Belt and
others are squeezing the life right out of us.
The belts we wear, just by virtue of where
we live, make us more likely to have a stroke,
suffer from type 2 diabetes or die from cancer.
But the College of Medicine at the
University of Tennessee Health Science Center
is working to loosen them all.
The effort to unbuckle the Stroke Belt,
which surrounds 11 states including Tennessee,
Arkansas and Mississippi, got a major boost
when Andrei Alexandrov, MD, joined UTHSC
in March as chair of the Department of
Neurology and Semmes-Murphey Professor.
Dr. Alexandrov was recruited to Memphis to
By Peggy Reisser Winburne
bolster decades of work done to combat stroke
in the Mid-South.
He builds on the efforts of physicians
including William Pulsinelli, MD, PhD,
former chair of Neurology, who for 20 years
grew the research, education and clinical
aspects of the department; Rick Boop,
MD, professor and chair of Neurosurgery,
who is working to improve clinical care
by promoting teamwork between local
neurologists and neurosurgeons; and
Guy Reed, MD, professor and chair of the
Department of Medicine, who is researching
better stroke treatments for the future.
Each brings his own skills, focus and point
of view, but they stand together on the front lines
in the battle against stroke in the Mid-South.
Next ... The Plan
Medicine Summer 2014 19
Medicine
The Plan
A
Loosening the Stranglehold of the
STROKE BELT
Taking Stroke Care to a Whole New Level
native of Moscow, Dr. Alexandrov,
has set his goals, and is attacking
them with the resolve of a general
and the warmth of a healer. He aims to set
up a citywide stroke service, improve and
speed up community access to vascular
or stroke neurologists, raise community
awareness of the symptoms and signs of
stroke, and recruit and train doctors who
will make sure the Stroke Belt doesn’t
constrict us in the future.
A big job, but he is ready. “It is exciting
what we can build here,” he says.
The Man
Dr. Alexandrov says he got “a Russian
welcome” on his first day on campus,
March 3. It snowed.
Some might say fitting weather
for the neurologist, who received his
MD degree in 1989 from First Moscow
Medical Institute in Russia, and
specialized in clinical neurology at the
Institute of Neurology, Russian Academy
of Medical Sciences in Moscow. He
completed his fellowship training in
stroke and cerebrovascular ultrasound
at the University of Toronto and the
University of Texas.
Dr. Alexandrov, 47, came to UTHSC
from the University of Alabama at
Birmingham (UAB), where he was
a professor in the Department of
Neurology and director of the Division of
Cerebrovascular Diseases. He also served
as director of the Comprehensive Stroke
Center and the Neurovascular Ultrasound
Laboratory, and was medical director of
the Stroke Service and the Intermediate
Care Stroke Unit at the University of
Alabama Hospital in Birmingham.
He says he chose Birmingham
because it is in the middle of the Stroke
Belt. His colleague, George Howard, PhD, a
professor of Epidemiology and Biostatistics
at UAB School of Public Health, has spent
years there on the National Institutes of
Health-funded REGARDS study (Reasons
for Geographic and Racial Differences in
20
Stroke) trying to uncover factors for the
The Mantra
strong predisposition to stroke that runs
“Time is brain,” Dr. Alexandrov says.
in families in this area. Dr. Alexandrov
That’s the reason he feels so strongly
worked on several projects with Dr.
about expanding and revving up the
Howard to analyze data from REGARDS.
stroke response system to reduce time to
The same geographical area as the Bible treatment, particularly for patients with
Belt, the Stroke Belt surrounds a population acute stroke.
that smokes more, eats more fried food, and
“The longer a blood clot sits there, the
suffers more frequently from high blood
more brain cells die,” he says. “If you’re
pressure, all of which make residents twice
having symptoms of stroke, you only have
as likely to have a stroke.
one hour to decide to do something, and
In Birmingham, Dr. Alexandrov set up
that hour will largely determine how you
a stroke response system that made UAB
are going to spend the rest of your life.”
Hospital and its Stroke Service available
Even a TIA (Transient Ischemic
to many emergency rooms in Greater
Attack) or mini- or warning stroke needs
Alabama and surrounding states. This
immediate attention. “A person who has
system changed the way acute strokes were
this, a weakness in one side of the face,
treated in Alabama and produced some of
slurred speech, inability to talk, a weak
the highest treatment rates in the nation.
arm or leg – even briefly – these people are
But calls from David Stern, MD, executive
at high risk of developing a stroke within
dean of the UTHSC College of Medicine,
the first two days,” he says. Currently, such
and Tulio Bertorini, MD, then-interim chair patients may not seek care if symptoms pass,
of Neurology, presented a bigger challenge
or may have to wait a week or two to be
and more potential in Memphis.
seen by a physician because of the limited
“The attraction here in Memphis is
number of stroke neurologists locally.
that there are two prominent hospital
“We want these patients to come to
systems, Methodist and Baptist, and both
the emergency room, whatever emergency
systems are actually recognizing stroke as room, and they will be seen by a stroke
a major burden and are willing to consider specialist, and that’s what we will be
working with the university physicians
opening here, a kind of fast-track access for
to develop a much more efficient system,
these patients to the specialists.“
which would bring specialists to their
Methodist University Hospital, a core
campuses,” Dr. Alexandrov says. “My
teaching hospital for UTHSC, now takes
long-term goal is to build a citywide
the majority of stroke patients from the
stroke program that would cover not
community in its comprehensive Stroke
only Methodist and participating
Center and Neurovascular Center. Dr.
institutions, but eventually, Baptist and
Alexandrov serves as medical director of the
their participating institutions. University center and a member of the stroke response
stroke physicians already cover the
team. A fast-access walk-in clinic for TIA
Regional Medical Center, and we are open patients will be located there, too.
to collaboration with everyone who cares
for stroke victims in the tri-state area. So
that means anywhere the patients come to
the closest emergency room, they will end
up being seen by a stroke neurologist.”
Continued
Discussions are under way to develop
such a wide-ranging system.
“It’s an exciting opportunity here to
build a really, really cutting-edge citywide
stroke program, which is almost impossible
in other places in the United States because
of competition between institutions.”
From Moscow to Memphis
You might say that caring for the brain is a
family affair for UTHSC’s new chair of the
Department of Neurology.
“Both of my parents are neurologists,”
says Andrei Alexandrov, MD. “But they never
influenced me.” His wife, Anne Alexandrov,
also is a professor in the College of Nursing
at UTHSC and a stroke specialist.
Dr. Alexandrov says he initially wanted
to be a physicist. That is, until the math
skills of a high school classmate, who is
now at Princeton University, intimidated him.
“I thought, ‘I like science, so what is the
more manageable thing for me,’ and it turns
out medicine was equally exciting, but did
not require the high math skills,” he says.
Neurology, however, was not in
the picture early on. “In medical school,
I wanted to be anybody else but a
neurologist,” he says. “My teacher during
my rotation of neurology just completely
won me over.”
Andrei Alexandrov, MD
Medicine Summer 2014 21
“Time is brain.”
Andrei V. Alexandrov, MD
Loosening the Stranglehold of the
STROKE BELT
The Methods
Increasing the number of stroke neurologists
and access to them across the city will
mean that more stroke victims will have a
better chance to receive the only effective
therapy approved by the FDA to reverse
neurological damage from stroke – a clotbusting medicine called tissue plasminogen
activator (tPA). At least 85 percent of strokes
are caused by clots within a blood vessel that
supplies oxygen to the brain. This medicine
must be given by intravenous injection
within four and a half hours after onset of
stroke symptoms to dissolve such clots. The
earlier it is given, the better the chances of
limiting lasting damage to the brain.
Most emergency rooms now carry tPA.
But less than half of all patients arrive at
the hospital early enough to benefit from
any treatment, and less than 5 percent get
tPA in time. That’s because of the time it
takes to transport patients and evaluate
them to determine if the drug is an
appropriate treatment.
At Methodist University Hospital, where
the high-volume stroke team works closely
with the Memphis Fire Department and
Emergency Medical Services, the average
time to treatment is at more than two hours
from symptom onset. This is not unusual in
Memphis or in the nation, Dr. Alexandrov
says, but there is room for improvement.
“It is clear to us that acute stroke
management in the U.S. needs to be
restructured to allow rapid screening
and treatment of stroke patients with tPA
therapy,” he says. “Based on past data, we
estimate if we can treat a patient within
one hour of symptom onset, the patient
would have over a four times greater
likelihood of complete recovery, compared
to later treatment.”
It’s a hypothesis he intends to test in
Memphis. To do that, he hopes to:
• Bolster the stroke team by recruiting
more vascular stroke specialists to
Memphis and “growing” them through
fellowship and residency programs.
• Establish a telemedicine system
linking the flagship Stroke Centers
with emergency rooms in the region to
eliminate travel time, expand diagnostic
access and speed treatment.
• Equip a specialized ambulance for prehospital stroke treatment. This mobile
unit would have all the diagnostic tools
and stroke medicine competence needed
for therapeutic decisions at the site. A
stroke specialist could go to the patient
and be able to assess, diagnose and begin
treatment, instead of waiting until the
patient arrives at the hospital.
• Better educate the public about the
signs, symptoms and treatment of
strokes and TIAs.
• Encourage development of all aspects of
academic neurology and stroke research
Dr. Alexandrov is mindful of the
good work that has been done in Memphis
and the systems already in place here to
combat stroke. “We just need to take it to
the next level.”
Help Wanted
The community is a key player in the best
stroke care.
Fast access and expanded treatment can
help only if the community is well-versed in
recognizing the symptoms of stroke and quick
to act if they surface.
According to the National Stroke
Association (stroke.org), the symptoms include:
• Weakness in an arm or leg
• Drooping or numbness of one side of the face
• Confusion, slurred speech, difficulty
understanding
• Trouble seeing in one or both eyes
Next ... A Firm Foundation
• Dizziness, trouble walking, loss of balance
or coordination
• Severe headache without a cause
“Treating stroke is a very time-sensitive
issue,” says Dr. Alexandrov, who advises calling
911 immediately if you suspect someone is
having a stroke. “Every second counts.”
22
22
Medicine Summer 2014 23
A Firm Foundation
W
Loosening the Stranglehold of the
STROKE BELT
Twenty Years of Progress in Stroke Research, Education and Care
illiam Pulsinelli, MD, PhD, was
drawn to Memphis and the
University of Tennessee Health
Science Center in the early 1990s because
he felt he could make a difference here.
“The fact that this part of the country had
an incidence of stroke higher than virtually
anyplace else. That is one of the reasons
I decided to leave New York and come
to Memphis,” says Dr. Pulsinelli, who left
Cornell Medical College/New York Hospital
in 1992 to become chair of the Department of
Neurology and Semmes-Murphey Professor
at UTHSC. “The opportunity to study stroke
here was extraordinary.”
In the 20 years he held that position,
Pulsinelli made his mark, successfully
working to improve stroke medicine
in Memphis and modernizing the way
the UTHSC College of Medicine trains
those who practice it. He stepped down
as chair in 2012, but continues to lend his
expertise to ongoing efforts to grow and
strengthen academic and clinical aspects
of neurology and stroke care in the region.
“The plan was when I turned 70, which I
did almost two years ago, I would step down
as chair, and so I did, and that I would retire
shortly thereafter, which I am slowly doing,”
Pulsinelli says. “I am delighted that Dr.
Andrei Alexandrov has joined the program,
and I’m hoping he has success in further
developing stroke care here.”
Dr. Pulsinelli came to Memphis from
one of the top neurology programs in
the country. He left Cornell/New York
Hospital in the third year of a five-year, $7
million grant from the National Institute
of Neurological Disorders and Stroke for
basic and clinical stroke research, and set
out to bolster the academic aspects of the
department at UTHSC through recruiting
faculty and boosting research.
“We went from having virtually no
research grants when I arrived, to when I
finished up two years ago, $3 million roughly
of NIH grants and also pharmaceuticalbased grants,” says Pulsinelli, whose own
research has focused on how disturbances of
blood flow cause damage to brain cells. “The
Neurology faculty members are publishing
on average 50 or so peer-reviewed
manuscripts a year.”
Establishing a Stroke Center
Dr. Pulsinelli took on the monumental
task of working with area institutions to
establish a certified Stroke Center for the
community, first with Baptist Memorial
Hospital until its move east in 2000, and
later with the Regional Medical Center.
“It didn’t move anywhere near as
quickly as I had hoped it would, but we
made significant progress in stroke care
here,” Pulsinelli says. As early as 1997, he
worked closely with the administration at
Baptist to develop standardized orders for
the use of tissue plasminogen activator, an
FDA-approved medication that if given
within three to four hours of a stroke
may improve chances of recovery. “The
medication only became available in 1996,
While chair of the Department of Neurology at UTHSC, William Pulsinelli, MD, PhD, worked for 20 years to improve stroke research, education and care.
so very quickly, within a year or so, we
had things set up to be providing it to the
population of Memphis,” he says.
The efforts paid off when Methodist
University Hospital, a core teaching
hospital of UTHSC, was certified as a
Stroke Center by The Joint Commission.
“Stroke care here now is probably
cutting edge,” he says. “When friends of
mine ask me ‘where do I go if I have a
stroke,’ I tell them to go to Methodist.”
Improving Medical Education
But cutting-edge stroke care is only as
good as the doctors who administer it, and
they are only as good as the training they
receive. Dr. Pulsinelli has led the drive to
improve that training, too.
Chair of the basic science curriculum
revision committee, Dr. Pulsinelli
instituted a “flipped classroom” concept in
neurology training.
“As we became involved with
curriculum revision and became aware
of some new teaching strategies, I didn’t
wait for a decision to come down from
the top to make a change in the clinical
neuroscience course,” he says. In a flipped
classroom, instead of the traditional
teaching model with a professor lecturing,
prerecorded lectures are available online
for students to view. Class time is spent
with the professor guiding students in
discussions and problem-solving exercises
in various case scenarios.
“The students seem to enjoy it, and the
faculty members love it, once they’ve done
it,” he says. “It’s a tremendous amount of
work to get it going, but it probably is a
more effective way of teaching.”
Dr. Pulsinelli believes the citizens of
Memphis will benefit from the emphasis
David Stern, MD, executive dean of
the College of Medicine, is placing on
combating stroke in partnership with
area hospitals.
“They’re making it possible to provide
the resources, I hope, for Dr. Alexandrov
to be successful in continuing to develop
stroke care,” he says.
Next ... A United Front
24
24
“... this part of the
country had an incidence
of stroke higher than
virtually anyplace else ...
The opportunity
to study stroke here
was extraordinary.”
William Pulsinelli, MD, PhD
(Above) Human brain model used to teach students about the blood supply to the brain
Medicine Summer 2014 25
“With that program up and
running, we’re now not just
taking care of people at one
hospital, but taking care of
people in the whole city.”
Rick Boop, MD
A United Front
A
STROKE BELT
Departments of Neurology and Neurosurgery Battle Stroke Together
major step in loosening the
bind of the Stroke Belt involves
tightening the bonds between
the Departments of Neurology and
Neurosurgery at UTHSC.
Rick Boop, MD, professor and chair of
Neurosurgery at UTHSC, is front and center
in helping to accomplish this. A pediatric
neurosurgeon, Boop doesn’t see a lot of
strokes in his clinical practice at Le Bonheur
Children’s Hospital, but as a department
chair, he oversees program development
for neurosurgery in the city and works with
physicians who do see them.
Dr. Boop was a member of the
search committee that brought Dr. Andrei
Alexandrov to Memphis to head the
Department of Neurology and helm the
efforts to move the already strong local stroke
treatment program into national prominence.
“I think the citizens of Memphis are
enjoying better care for hemorrhages in the
brain, aneurysms and strokes than they’ve ever
had before,” Dr. Boop says. “We’re hoping the
level of neurocritical care will continue to
get better and better.”
Our spot at the buckle
of the Stroke Belt means
our stroke program is
one of the largest in
the nation. “And with
the new Neurology
chair search under
way, we thought
this program is
so much at the
forefront in the
nation, it was
important to bring
someone in as
a chairman who
could help continue
to build that
program and take it
one step further,” Dr.
Boop says. “That’s how
Dr. Alexandrov became
a top choice.”
The framework on which Dr.
Alexandrov will build a citywide stroke
response team, Dr. Boop says, has been
laid by neurologists and neurosurgeons
working together in Memphis.
Physicians of the Semmes-Murphey
Neurologic & Spine Institute, one of
the largest groups of neurosurgeons
and neurologists in the country,
historically have provided oversight of
the residency and fellowship training in
neurosurgery locally.
Adam Arthur, MD, a neurosurgeon
with Semmes-Murphey and an associate
professor at UTHSC, has spent the
better part of a decade building a
citywide vascular-endovascular program
of neurosurgeons, neurologists and
interventional neuroradiologists
offering state-of-the-art surgical and
interventional care to patients at various
hospitals in town.
Rick Boop, MD, believes closer cooperation
between the Departments of Neurosurgery and
Neurology at UTHSC will result in better stroke care.
Photo: Lisa Buser
26
26
Loosening the Stranglehold of the
“With that program up and running,
we’re now not just taking care of people at
one hospital, but taking care of people in
the whole city,” Dr. Boop says. “It’s raising
the bar so that everyone in the city, no
matter which hospital they end up going
to, even people in the region if they get
transferred to one of the hospitals in the
city, can enjoy the same quality of care in
all the different hospital systems.”
Neurology, a branch of internal
medicine, treats disorders of the nervous
system, brain, spinal cord, nerves and
muscles. Neurosurgeons perform surgical
treatment on the brain or nervous system.
Dr. Alexandrov’s plans to build a citywide
system of stroke or vascular neurologists
who work with the established vascularendovascular program will further boost
stroke critical care in the region.
“The program is there, but we’re hoping
Dr. Alexandrov will take it to a national level
of prominence,” Dr. Boop says. “Dr. Arthur
is a neurosurgeon and Dr. Alexandrov is a
neurologist, so for people who might need
surgery, hopefully, Dr. Alexandrov
would call Dr. Arthur. We’re hoping
there will be synergy here.”
Dr. Boop is confident
that Dr. Alexandrov, a
national leader in stroke
and neurocritical care, is
the right person at the
right time to take this
relationship to new levels.
“He’s coming here
and he’s bringing
to us new research
protocols; he’s
bringing to us new
technologies we’ve
not had in this city
before; he’s bringing
to us new teaching and
training paradigms for
medical students, as well
as residents and fellows; he’s
recruiting good, quality people
to come to Memphis and help
build this program,” Dr. Boop says.
“It will certainly raise the level of care for
people who have strokes.”
Next ... The Key to the Future
Medicine Summer 2014 27
The Key to the Future
G
STROKE BELT
UTHSC Researchers Pursue Better Methods to Treat Stroke
uy Reed, MD, traces his quest to
find a better way to treat strokes
back to his days in training.
“What motivated me was to watch
a patient come in with symptoms of a
stroke, and then watch him progressively
deteriorate and die because there wasn’t
anything we could do for him,” says Dr. Reed,
a cardiologist and chair of the Department
of Medicine at UTHSC. “I just realized we
didn’t understand what was going on, we
didn’t understand what was causing it, and
we didn’t have a safe way of approaching
the problem because the current therapies
we had were too risky and had their own
problems. We needed a way to improve care.”
Dr. Reed began more than a decade ago
to actively research a safer, more effective
therapy for dissolving blood clots, which are
the cause of most strokes. Currently, tissue
plasminogen activator is the only proven
treatment for dissolving blood clots. It is
effective on the right patients, but must
be given within a certain window of time
from onset of symptoms, and can cause
Dr. Guy Reed, right, and members of his team, including Aiilyan Houng, are researching better ways
major bleeding. “Over time, the benefit of
to treat ischemic stroke.
tPA declines and the toxicities rise, so it’s a
competing risk-benefit ratio,” he says.
Dr. Reed sees research as a responsibility
“I think more needs to be done in
“It ends up being used in only five
of any medical university in the battle
getting patients to recognize the onset of
percent or less of the patients who have
against disease.
stroke, getting them to understand what
ischemic stroke,” Dr. Reed says. “So the
“As an academic health center, we
the symptoms might be, getting people to
challenge really has been to find a way to
hospitals and treated earlier,” Dr. Reed says. really have a primary mission of educating
treat patients in a way that doesn’t enhance “But the key would be to make a treatment
people to learn the best current knowledge
their risk of a side effect that might cause its that’s safer that you could give to a larger
of how to diagnose and treat disease and
own disability or its own mortality.”
improve health,” he says. “But we also
group of patients over a longer period of
Dr. Reed, who has been at UTHSC
have an obligation to advance the field, so
time after a stroke.”
for six years, is the principal investigator
The original research that led to stromab that we can discover new ways and better
in research funded with a total of roughly
ways to treat and prevent disease, so that
was designed to identify what regulates clot
$7 million from the National Institutes of
in 2020, we’re not still treating people the
dissolution in the body, Dr. Reed says. The
Health that has developed a monoclonal
same way with the same therapies we’re
team identified a molecule as the agent, and
antibody called stromab that’s shown to
using in 2014.”
then made an antibody that inhibited that
rapidly and safely dissolve blood clots and
And he hopes those who will be
molecule, and the blood clots dissolved.
prevent ischemic brain injury, hemorrhage
administering those therapies keep
They thought this might have utility in
and disability when compared with tPA or
something in mind.
humans, and studied it progressively in
controls. Dr. Reed and his seven-member
“It’s important that we keep as a central
mice, ferrets, rabbits and so on. “It looks very
team seek to develop stromab as the first
promising,” he says, adding it could be useful part of our mission research and efforts
approved, new class of clot-dissolving agents
to discover new ways to treat and prevent
beyond stroke for other problems caused by
since tPA was introduced decades ago.
disease, and that medical students and
thrombi or blood clots.
They are producing stromab for
residents and fellows think about that
“It’s the only research on this molecule
Phase I trials targeted for January 2015
pathway as a potential career to accomplish
in the country,” Dr. Reed says. “There are
to test on key biomarkers in humans,
their goals of making the community
many other different approaches to stroke
and Phase II trials as a therapeutic for
healthier in addition to their practice of
going on, but I hope for all of us at least
stroke patients late next year.
medicine,” Dr. Reed says. “You can do both.”
one of them is effective.”
28
“... the key would be
to make a treatment that’s safer
that you could give to a larger
group of patients over a longer
period of time after a stroke.”
Loosening the Stranglehold of the
Next ... The Big Picture
Guy Reed, MD
Medicine Summer 2014 29
“Our goal is a
College of Medicine,
not just in, but for
Memphis.”
David Stern, MD
30
The Big Picture
D
Loosening the Stranglehold of the
STROKE BELT
An Engaged College of Medicine Means a Healthier Community
avid Stern, MD, executive dean
of the College of Medicine, has
his sights set on the major health
problems plaguing the region.
The Stroke Belt is not the only target –
diabetes, lung cancer, renal disease,
health disparities, obesity – all are in
his crosshairs. And as his doctors at the
College of Medicine take them down, they
build the community up.
“The College of Medicine is dedicated
to providing outstanding training to the
next generation of physicians, and to being
an active force in improving the overall
health of our community,” says Dr. Stern.
“That means we focus on developing
and providing cutting-edge care when
people are sick, and offering services and
solutions that help keep them well.”
While the dean prefers to stay in the
background, he is assembling a worldclass team to help him achieve his vision.
Dr. Stern says his goal is to bring added
value to the community by recruiting
specialists to the College of Medicine, like
Dr. Alexandrov, who bring new skills and
approaches to the excellent education,
clinical care and research at UTHSC.
“We are trying to increase the health
and wellness of Memphis,” Dr. Stern
says. “Dr. Alexandrov is charged with
developing a citywide comprehensive
Neurology Department that embraces
the whole community and multiple
health systems. He will be working closely
with his colleagues in Neurosurgery to
develop seamless coordination of care for
patients with neurological disorders. His
experience in translational and clinical
research will invigorate stroke care
throughout the city.”
Dr. Stern’s plans also include setting up
Centers of Excellence to target these major
health concerns; caring for vulnerable
populations; and embedding the College
of Medicine in the community with public
service work and the best possible clinical
care performed by UTHSC doctors at our
partner teaching hospitals.
“Our goal is a College of Medicine,
not just in, but for Memphis.”
David Stern, MD, executive dean of the College
of Medicine at UTHSC, has his eye on making
the community a healthier place to live.
Medicine Summer 2014 31
Alumni & Development
Karen Kaufman-Codjoe MD, MPH
Hometown: Memphis, Tenn.
Family: Three Children (Ellis Codjoe. Seattle, Wash. ; John Codjoe, DDS Hyannis, Mass.; Ama Codjoe, New York, N.Y.) and four grandchildren
Education: Undergraduate Degree: BA 1973 – Macalester College, St. Paul, Minn.; MD 1978 – University of Tennessee Health Science Center;
Pediatric Residency 1979-1982 – Brackenridge Hospital, Austin, Texas, 1979-1983; MPH 1990 – Ohio State University, Columbus, Ohio
Specialty: Board Certified – Pediatrics; Board Eligible – Preventive Medicine
What is your favorite UT memory as a student?
“Being noted as a trailblazer for being Black and female and then working extremely hard to accomplish the goal of becoming a physician.
Meeting fellow students and faculty that went on to become lifelong friends was very special. It was a memorable experience training at
the hospital where I was born (John Gaston).”
Why did you select UT COM?
“After living in Minnesota for college, I wanted to come back home for affordable medical school training and to be close to family.
The warmer weather was a big plus.”
What are some highlights of your professional career?
“Director of Ambulatory Pediatrics, St. Elizabeth Health Center, Youngstown, Ohio, 1983-1997; Assistant Professor of Pediatrics,
Northeastern Ohio Universities College of Medicine, 1986-1997; Clinical Assistant Professor of Pediatrics, Ohio University College
of Osteopathic Medicine, 1986-1997; Youngstown Board of Health, 1989-1994; Miles V. Lynk Medical Society, Secretary, 1999-2002;
Volunteer State Medical Association – President, 2005-2007”
What UT volunteer positions have you held?
“Alumni Council 2012-present”
Why did you get involved?
“I lived outside of the state for a lot of my career. When I moved
back to Tennessee, I was impressed with all the changes at UTCOM
and welcomed the opportunity to serve on the Alumni Council
and get an up-close look at the medical school that provided
me with an excellent foundation for my career in medicine.”
What is your advice to other UT Alumni
about getting involved?
“Most of us entered medical school with the vision
of helping others. Getting involved with UTCOM
affords an opportunity to do that by working
with the students, bringing community needs
to the table, and as a community leader staying
informed about resources available at the
university that is training the next generation
of doctors. Doctors with experience have
a lot to offer the medical school in the way
of real-world experience. The more diverse
this experience pool is the greater are
the benefits for all.”
32
Medicine Summer 2014 33
Medicine
Alumni & Development
Thursday, August 14
2014 Outstanding Alumnus Award Recipients
9:00 a.m. – 10:30 a.m.
Executive Committee Meeting
UTHSC Campus
———————————————————————————————————————————————————————————————
11:30 – 4:00 p.m.
Alumni Council Meeting
Center for Cancer Research – UTHSC Campus
———————————————————————————————————————————————————————————————
6:30 p.m. – 9:00 p.m.
Outstanding Alumni Awards Dinner
Venetian Ballroom – Peabody Hotel
COST: $50/PERSON
————————————————
Friday, August 15
7:15 a.m. CME Registration and Continental Breakfast
Freeman Auditorium – Hamilton Eye Institute
———————————————————————————————————————————————————————————————
8:00 a.m. – 12:00 p.m.
Plenary Sessions – FREE EVENT!
Freeman Auditorium – Hamilton Eye Institute
———————————————————————————————————————————————————————————————
8:30 a.m. – 9:30 a.m.
Continental Breakfast for Spouses and Those
Not Attending CE Program – FREE EVENT!
Jackson Room – Peabody Hotel
———————————————————————————————————————————————————————————————
11:00 a.m.
Keynote Address: Update on Diabetes
Management in the Community
Freeman Auditorium – Hamilton Eye Institute
Irl B. Hirsch, MD
Professor of Medicine
The Diabetes Treatment and Teaching Chair
The University of Washington School of Medicine
FREE EVENT!
———————————————————————————————————————————————————————————————
12:30 p.m. – 1:30 p.m.
UT Health Science Center Walking Tour
Advance reservations requested.
Minimum of 25 people required.
FREE EVENT!
———————————————————————————————————————————————————————————————
3:00 p.m. – 4:30 p.m. College of Medicine White Coat Ceremony
Mississippi Boulevard Christian Church
———————————————————————————————————————————————————————————————
6:00 p.m. – 7:00 p.m.
Networking Reception for Alumni & Students
Hernando DeSoto Room & Club Bar – Peabody Hotel
FREE EVENT!
———————————————————————————————————————————————————————————————
7:00 p.m. – 9:00 p.m. Class Reunion Dinners
————————————————
Saturday, August 16
7:00 p.m. – 9:00 p.m. Class Reunion Dinners
———————————————————————————————————————————————————————————————
Note: Room locations are subject to change.
34
Jack B. Alperin, MD, FACP ’57
Jesse J. Cannon, Jr., MD ’76
James D. Link, MD ’61
Dana V. Wallace, MD ’72
For more details, visit the 2014 Medicine Alumni Weekend website at
www.uthscalumni.com/2014MedicineWeekend. Registration opens Tuesday, June 17!
Keynote Address by Irl Hirsch, MD
Dr. Irl Hirsch is a professor of medicine and
holds the Diabetes Treatment and Teaching
Chair at the University of Washington School of
Medicine in Seattle. He went to medical school
at the University of Missouri in Columbia, Mo.,
trained in internal medicine at the University of
Miami in Miami, Fla., and Mount Sinai Hospital
in Miami Beach. Dr. Hirsch completed a research
fellowship at Washington University in St. Louis.
Dr. Hirsch has been interested in new
technologies for the treatment of diabetes,
particularly those involved in the use of insulin
therapy. He has been involved in numerous
major clinical research trials, including the
DCCT, ACCORD, STAR-1, JDRF Sensor Trial,
SEARCH, ORIGIN, ADAG and many more. He
has authored more than 140 papers including
a review of insulin in the New England Journal
of Medicine, more than 50 editorials, three
commentaries in “Journal of the American
Medical Association,” numerous book chapters
and four books both for patients and physicians.
Dr. Hirsch is the past editor-in-chief of DOC
News and Clinical Diabetes and the former chair
of the Professional Practice Committee for the
American Diabetes Association. He has served
as a member of the Endocrine Section of the
American Board of Internal Medicine.
Irl B. Hirsch, MD
Medicine Summer 2014 35
Alumni & Development
You’re Invited to
Golden
Graduate
Homecoming
OCTOBER 15-17, 2014
MEMPHIS, TN
HONORING GRADUATES OF 1964
FROM ALL SIX UTHSC COLLEGES
We are planning the following events just for you:
• Dinner at the Rendezvous
• College Open Houses
• Lunch with the Chancellor
• Golden Graduate Ceremony
• UT vs. Ole Miss football package and more!
All class years prior to
1964 are invited to attend.
Once a Golden Graduate,
always a Golden Graduate.
Please watch your mailbox
for a detailed event brochure.
Call (901) 448-5516 or visit
uthscalumni.com for more information.
Please Save the Date!
College of Medicine Alumni Reception
in Knoxville, Tenn.
Featuring University of Tennessee and College of Medicine leadership and special guests
Friday Evening, October 24
(Evening before the UT vs. Alabama game)
Cherokee Country Club
Questions?
Please call Kelly Davis, Regional Director of Development,
at 901-448-5516 or [email protected]
36
The College of Medicine Needs Your Support!
W
ould you like to find a way to give
back to the College of Medicine? Did
you receive scholarship support while
attending UTHSC and would like to now offer
support for future students? Would you like
to honor a past mentor or professor? Do you
want to see the UTHSC College of Medicine
reach new heights in educating medical
students, conducting research, and caring for
patients in Tennessee and beyond?
If you answered yes to any of these
questions, please consider making a gift
today. Donations from alumni, residents, past
trainees and fellows, former and current
parents, community advocates, corporations
and foundations, and friends new and old of
the College of Medicine are one of the key
drivers in making the college exceptional.
There are countless areas at the UTHSC
College of Medicine that can benefit from
your support, including student scholarships,
research, departmental-based support, or
funding entirely new initiatives. There are
so many ways to contribute, too — onetime gifts or multiple-year pledges, IRA
designations, simple bequests, and more.
We can help you find the best way for you to
contribute to the College of Medicine.
Please contact Zach M. Pretzer, CFRE,
Director of Development for the College of
Medicine, at (901) 448-4975 or via email
at [email protected] to learn more about
how to donate to the College of Medicine.
Below are examples of some of the College of Medicine’s minimum endowment levels.
The minimum amount required to name and endow a fund is $25,000. Gifts can be
pledged up to a period of five years. For example, five annual gifts of $5,000 would
name/endow a $25,000 fund, such as a student scholarship, at the end of year five.
CHAIR – $2,000,000 or more
Provides substantial salary support for a
College of Medicine faculty member and their
related research, library, and travel expenses.
The dean, or the appropriate academic officer,
determines specific criteria with approval of
the Chancellor.
PROFESSORSHIP – $1,500,000 or more
Provides a salary supplement and/or related
research, library, and travel expenses. The
dean of the College of Medicine, or the
appropriate academic officer, determines
specific criteria with approval of the Chancellor.
DISTINGUISHED VISITING
PROFESSORSHIP – $100,000 or more
Provides honorarium and travel expenses
for a visiting professor, plus event expenses
for addressing several audiences (students,
faculty and community professionals).
RESEARCH AND DEVELOPMENT FUND –
$100,000 or more
Supports research in the field designated
by the donor.
LABORATORY – $75,000 or more
Provides naming rights for an available
laboratory space.
LECTURESHIP – $60,000 or more
Provides honorarium and travel expenses
for a lecture by a noted scholar.
FACULTY DEVELOPMENT FUND –
$50,000 or more
Supports College of Medicine faculty in
developing their careers through study,
research, travel and professional activities.
SCHOLARSHIP – $25,000 or more
Creates an endowed scholarship fund for
the College of Medicine that will benefit
current or entering students in need
and/or to reward outstanding academic
performance.
MINIMUM ENDOWMENT – $25,000 or more
Any of these opportunities may be provided in
one payment or be built to this level over a fiveyear period. All endowment gifts may include
naming rights as well.
Medicine Summer 2014 37
Alumni & Development
UTHSC Launches 1911 Society for Donor Recognition
O
n July 1, 2013, the UT Health Science Center
Office of Development and Alumni Affairs
unveiled a new donor recognition society.
Named the 1911 Society in honor of the year that
our campus was started, this new recognition
opportunity acknowledges donors who
make annual, recurring gifts that serve as the
renewable basis of private support each year.
“Members of the 1911 Society are the leaders of
our past, present and future,” said Bethany Goolsby,
associate vice chancellor for Development at UTHSC. “The
ongoing, annual support of our alumni and friends provides funding
necessary for administrators, faculty and students to succeed in all
areas of health care training, education and community service.”
All donors whose gifts to the UT Health Science Center totaled
between $100 and $10,000 during the period July 1, 2012 through
June 30, 2013 were granted charter membership in one of the six 1911
Society giving levels. Charter membership will also be extended to
all individuals who give at 1911 Society membership levels between
July 1, 2013 and June 30, 2014. Membership level is based on total
contributions across six different levels of private support.
To be named in one of the 1911 Society
recognition levels, donors can direct gifts to any
college, program or fund at the UT Health Science
Center. “That is the unique aspect of this level of
recognition,” said Goolsby. “We want to proudly
identify individuals who are supporting the
Health Science Center with their financial
resources each year.” Members will be listed
in a 1911 Society Roll of Honor to be published in
various newsletters, magazines and other publications
throughout the year.
As members of the 1911 Society, donors are recognized as vital
partners of the UT Health Science Center community. Depending
on membership level, various benefits are available to all members
along with the most obvious benefit — the satisfaction of knowing
that your support has provided meaningful resources for UT
Health Science Center faculty, students and staff.
Your loyalty matters to us ... and to you. And to our students,
faculty and staff as well. For more information on how to make a
gift and become a member of the 1911 Society, please contact the
UTHSC Office of Development and Alumni Affairs at (901) 448-5516.
1911 Milestone Member
1911 Visionary Member
1911 Dean’s Alliance Member
1911 Chancellor’s Circle Member
1911 Patron Member
1911 Hyman Associate Member
$100 - $249
$250 - $499
$500 - $999
$1,000 - $2,499
$2,500 - $4,999
$5,000 - $10,000
Well, you could be.
1911 Society Benefits
1911 Society Decal
FY13 and FY14 members are identified as Charter Members
Recognition in annual Roll of Honor
Collegiate and campus publications
Communication from UTHSC Students
Email, letter and/or postcard contacts
Communication from UTHSC Dean
New year correspondence, update after board meetings
Special Invitations to Campus Events
1911 Society Lapel Pin
Annual VIP Communication from the Chancellor
Special Recognition at Events
Note on rosters, note on nametags, recognized from the
podium when possible
38
Milestone
Visionary
Dean's Alliance
Chancellor’s Circle
Patron
Hyman Associate
$100 - $249
$250 - $499
$500 - $999
$1,000 - $2,499
$2,500 -$4,999
$5,000 - $10,000
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
Sneak Peek
For
For more
more than
than four
four decades,
decades, the
the UT
UT Alumni
Alumni Association
Association has
has
The
The 2014
2014 program
program will
will feature
feature 40
40
tours,
tours, beginning
beginning at
at only
only $714!
$714!
safe,
safe, exciting,
exciting, and
and affordable
affordable tours
tours to
to all
all corners
corners of
of the
the world.
world.
partnered
partnered with
with America’s
America’s finest
finest travel
travel companies
companies to
to provide
provide
Cruise
Cruise the
the Caribbean,
Caribbean, explore
explore the
the Swiss
Swiss Alps,
Alps, steamboat
steamboat down
down
the
the Mississippi
Mississippi River,
River, spot
spot wild
wild animals
animals on
on safari
safari in
in Africa,
Africa, sail
sail
through
through the
the Panama
Panama Canal,
Canal, discover
discover the
the sights
sights and
and sounds
sounds of
of
Well, you could be.
Southeast
Southeast Asia,
Asia, or
or enjoy
enjoy the
the company
company of
of fellow
fellow UT
UT alumni
alumni on
on
Sneak Peek
The 2014 program will feature 40
tours, beginning at only $714!
one
one of
of our
our 40
40 other
other tours.
tours.
For more than four decades, the UT Alumni Association has
Tempting,
isn’t
it?
Tempting,
isn’t
it? finest travel companies to provide
partnered with
America’s
safe, exciting, and affordable tours to all corners of the world.
Cruise the Caribbean, explore the Swiss Alps, steamboat down
the Mississippi River, spot wild animals on safari in Africa, sail
through the Panama Canal, discover the sights and sounds of
utaaconnect.com/tours
Southeast Asia, or enjoy the company of fellow UT alumni on
If
If you
you have
have any
any questions,
questions, please
please contact
contact the
the UTAA
UTAA at
at
one of our 40 other tours.
[email protected]
[email protected] or
or 865-974-2115
865-974-2115
Tempting, isn’t it?
Medicine Summer
Medicine
Summer 2014
2014 39
39
Alumni & Development
UT COLLEGE OF MEDICINE ALUMNI COUNCIL
C O L L E G E
O F
DidYou
M E D I C I N E
Know?
T H E
N U M B E R S
16
26
4
69
40
New
Inventions
Disclosed
Patents
Filed
Patents
Issued
NIH
Grants
Published
Articles
in 2013
Join the
Come Grow with Us!
The UT College of Nursing is looking for
faculty members with varied specialties
to educate and train the next generation
of nurses. We are seeking enthusiastic,
accomplished achievers with a passion for
both teaching and the nursing profession.
Do you know a doctorally prepared nurse –
with practice or academic credentials –
who has a love for learning and sharing
knowledge? Could be our next faculty member.
Faculty Positions Available
in Memphis and Nashville
Visit: www.uthsc.edu/nursing/jobs
Contact: Laura Beth Homonnay
Email: [email protected]
Office: (901) 448-6135 or (800) 733-2498
40
B Y
20 U.S.
6 International
in 2013
3 U.S.
1 International
in 2013
Funded for a Total
of $24.1 Million
FY2014 as of
6/4/2014
in Scholarly
Journals
FY2014 as of
4/7/2014
Nursing Faculty
President
THOMAS WHITAKER, M.D., ’70
Myrtle Beach, S.C.
President-elect
ROBERT KERLAN, MD ’69
Germantown, Tenn.
Vice President
LEONARD H. HINES, MD ’64
Lenoir City, Tenn.
Secretary
JOHN P. LITTLE, MD ’92
Knoxville, Tenn.
——————————————————————————
Past Presidents
PAUL HUFFSTUTTER, MD ’73
Lenoir City, Tenn.
JAMES W. MORRIS, MD ’72
Lebanon, Tenn.
WILLAM A. SIMS, MD ’61
Decatur, Ala.
JAMES C. FLEMING, MD ’74
Germantown, Tenn.
MARY C. HAMMOCK, MD ’81
Chattanooga, Tenn.
JERRALL PAUL CROOK, MD ’58
Nashville, Tenn.
ALBERT J. GROBMYER III, MD ’62
Memphis, Tenn.
WILLIAM N. WILLIFORD, MD ’70
Knoxville, Tenn.
OLIN O. WILLIAMS, MD ’53
Murfreesboro, Tenn. (deceased)
JOHN (MAC) HODGES, MD ’63
Memphis, Tenn.
JOE W. BLACK, Jr., MD ’57
Knoxville, Tenn.
JOHN K. WRIGHT, MD ’59
Nashville, Tenn.
JOHN H. BURKHART, MD ’45
Knoxville, Tenn. (deceased)
ARTHUR R. EVANS, Jr., MD ’50
Louisville, Tenn. (deceased)
ROBERT E. CLENDENIN, Jr., MD ’60
Union City, Tenn.
JOHN P. NASH, MD ’56
Memphis, Tenn.
JOHN K. DUCKWORTH, MD ’56
Nesbit, Miss.
——————————————————————————
UT Medical Center – Knoxville
MARK S. GAYLORD, MD ’78
Knoxville, Tenn.
UT Medical Center – Chattanooga
MICHAEL S. GREER, MD ’78
Chattanooga, Tenn.
——————————————————————————
Tennessee At-Large
KAREN CODJOE, MD ’78
Jackson
LORI EMERSON, MD ’83
Lookout Mountain
LEONARD H. HINES, MD ’64
Lenoir City
GARY W. JERKINS, MD ’77
Nashville
ROBERT KAPLAN, MD ’73
Memphis
RODNEY WOLF, MD ’61
Memphis
East Tennessee
THOMAS TREY CARR, MD ’04
Lookout Mountain
STEPHEN JACKSON, MD ’84
Cleveland
TARECK A. KADRIE, MD ’98
Signal Mountain
JOHN P. LITTLE, MD ’92
Knoxville
MOLLY J. PEELER. MD ’84
Knoxville
——————————————————————————
Middle Tennessee
JAN DELOZIER, MD ’87
Nashville
MORRIS D. FERGUSON, MD ’56
Lebanon
BILL HARB, MD ’99
Nashville
DAVID HILL, MD ’80
Nashville
——————————————————————————
West Tennessee
MICHAEL D. CALFEE, MD ’95
Union City
JAMES T. GALYON, MD ’53
Memphis
GENE MANGIANTE, MD ’75
Memphis
——————————————————————————
Out-of-State At-Large
JOHN E. HAMILTON, MD ’84
Florence, Ala.
ROBERT E. HOWE, MD ’57
Gardendale, Ala.
MICHAEL J. SMITH, MD ’73
Tierra Verde, Fla.
——————————————————————————
Region I
GERALD REICH, MD ’72
Rolling Hills, Calif.
——————————————————————————
Region II
RONALD JONES, MD ’57
Dallas, Texas
——————————————————————————
Region III
VACANT
——————————————————————————
Alabama
DEASON DUNAGAN, MD ’72
Arkansas
VACANT
Florida
GARY A. GROOMS, MD ’66
Georgia
VACANT
Kentucky
VACANT
Mississippi
VACANT
North Carolina
JONATHAN BURDETTE, MD ’93
South Carolina
ROBERT M. CALLIS, MD ’74
Texas
RANDAL S. WEBER, MD ’76
Virginia
VACANT
Emeritus
A. MITCHELL BURFORD, Jr., MD ’57
Florence, Ala.
LARRY P. ELLIOTT, MD ’57
Isle of Palms, S.C.
ALBERT M. HAND, MD ’42
Shreveport, La.
EVELYN B. OGLE, MD ’47
Memphis, Tenn.
LEROY SHERRILL, MD ’52
Chattanooga, Tenn.
DAVID H. TURNER, MD ’52
Chattanooga, Tenn. (deceased)
RALPH HAMILTON, MD ’52
Germantown, Tenn.
JOHN NASH, MD ’56
Memphis, Tenn.
——————————————————————————
Honorary
JOE E. JOHNSON, EdD
JAMES HUNT, MD
Chancellor of Health Science Center
Steve J. Schwab, MD
——————————————————————————
Executive Dean for the College Of Medicine
David M. Stern, MD
——————————————————————————
Special Assistant to the Chancellor
Hershel “Pat” Wall, MD
——————————————————————————
College of Medicine
James J. Neutens, PhD
Dean, College of Medicine
Knoxville
David C. Seaberg, MD, CPE, FACEP
Dean, College of Medicine
Chattanooga
——————————————————————————
Interim Foundation President & Executive Director
UT Alumni Association
Lofton Stuart
——————————————————————————
Vice Chancellor for Development and Alumni Affairs
Randy Farmer, EdD
——————————————————————————
Associate Vice Chancellor for Alumni Affairs
and Annual Giving
Kris Phillips
——————————————————————————
Director of Alumni Programs
Michelle Nixon, MBA
Chandra Tuggle
——————————————————————————
Associate Director of Alumni Programs
Monica Everett
——————————————————————————
Senior Director of Annual Giving &
Advancement Services
Jada Williams
——————————————————————————
Associate Vice Chancellor for Development
Bethany Goolsby Blankenship, JD
——————————————————————————
Director of Development
Zach Pretzer
Medicine Summer 2014 41
Faculty
L
en Lothstein, PhD, considers himself lucky. He’s
been a researcher at UTHSC for 25 years, and was
fortunate enough to have had the same research
assistant for 15 of those years.
“That’s highly unusual,” said Dr. Lothstein, an associate
professor of Pathology and Pharmaceutical Sciences. “As
often happens in laboratories, we hire someone as a lab
assistant, and they will, more often than not, stick around
for a year or two years, and then move on to a PhD
program or med school. We could hardly fault them for
doing that, but it’s a problem in continuity of research.”
Continuity
Conundrum
The
“... we hire someone
as a lab assistant, and
they will, more often
than not, stick around for
a year or two years, and
then move on to a PhD
program or med school.”
Dr. Len Lothstein
That’s why Dr. Lothstein has developed a new graduate program at UTHSC
designed to train qualified students to assume the technical staff positions of senior
laboratory assistant and laboratory manager in biomedical research labs in the academic,
government and private sectors.
The Master of Science in Laboratory Research and Management Program will begin
in the fall of 2014. The intensive three-semester program on the UTHSC campus will be
administered through the Department of Pathology in the College of Medicine, working in
tandem with the College of Graduate Health Sciences. It will offer theoretical and practical
laboratory experience, and also train students in the managerial and administrative
skills required of a senior research assistant or lab manager in basic and translational
biomedical research laboratories.
“What we want to do with this program is provide training in an academic
environment, so that when these individuals come out with a master’s degree, they can
step into a lab and become almost fully functional within a very short period of time,” he
said. “We want to train individuals whose goal is to stay in this position for a length of
time, eventually leading to a manager position, which can pay very nicely.”
A UT Professor Offers a New Solution to an Old Problem
Entry-level research lab assistants make from about $26,000 to $43,000 annually,
according to figures provided by Dr. Lothstein. Salaries rise with education and experience
to between $37,000 and $63,000, he said. Lab managers can make roughly $63,000 to
about $110,000.
The U.S. Department of Labor’s Bureau of Labor Statistics predicts 14 percent
growth for the laboratory assistant job classification over the next eight years, from an
estimated 82,000 jobs to an estimated 91,000 by 2020. This growth is anticipated
despite cutbacks in federal funding for research.
“We need to start training good support staff,” Dr. Lothstein said. This is important to
some extent because of government funding cuts, which take principal investigators out
of the labs in search of funding. “Without good technical staff, the work doesn’t get done.
If the work doesn’t get done, the grant money doesn’t come in.”
Dr. Lothstein said it’s important that the biotech community in Memphis be aware of
this new program. “They have a vested interest,” he said. “This is where their technical
staff will be coming from, which will improve the nature of research in town.”
The program will provide not only qualified graduates to fill research jobs, but also
interns who can help staff labs while they are still learning. “This program is providing
a skilled labor force that is needed both for the academic sector in this town and for
the biotech sector,” he said. “I want both to get fully involved and invested in this.”
Dr. Johnson Warns of Diet Drink Risks
K
aren Johnson, professor and interim chair for Preventive Medicine, co-authored an analysis of data presented
in March at the American College of Cardiology’s 63rd Annual Scientific Session in Washington, D.C. The
study showed drinking two or more diet drinks a day may increase the risk of heart disease, including
heart attack and stroke, in otherwise healthy postmenopausal women. The data was generated as part of the
observational arm of the Women’s Health Initiative, a multi-decade study, including three clinical trials, that
enrolled more than 100,000 women. UTHSC has enrolled more than 4,200 women in the study and has been
following them since 1993.
Tennessee Medical Association Honors UTHSC Physicians
T
wo UTHSC physicians were among the recipients of Tennessee
Medical Association (TMA) annual awards for 2014, presented
during the TMA’s Annual Convention.
Thomas C. Gettelfinger, MD, received a 2014 Distinguished Service
Award, presented annually by the TMA Board of Trustees to outstanding
members of the association for their notable achievements during the
past year.
Dr. Gettelfinger is a clinical professor in the Department of Ophthalmology
at UTHSC. An ophthalmologist at Memphis Eye and Cataract Associates, he
is affiliated with several Memphis hospitals. Dr. Gettelfinger has been active
in teaching and training in ophthalmology programs in third-world countries,
and participates in international charitable work with Orbis International, an
airborne surgical eye hospital that travels to developing countries.
Jon H. Robertson, MD, was honored with a 2014 Outstanding
Physician Award, given annually by the TMA House of Delegates to
member physicians who through their medical careers “make an
impression among their colleagues, peers and on the profession of
medicine in Tennessee.” He was nominated for his leadership in the area
of neurosurgery in Memphis and Shelby County.
Dr. Robertson was chair of the UTHSC Neurosurgery Department
from 1996 until 2011.
He has maintained an active practice in neurological surgery with
the Semmes-Murphey Neurological & Spine Institute for the past 35 years,
and has served on its board of directors for the past two decades.
The Tennessee Medical Association is the largest professional
organization for physicians in Tennessee, representing all medical specialties.
Dr. Edward Chaum Receives Wheeley Award
T
Len Lothstein, PhD
42
he University of Tennessee Research Foundation (UTRF) presented the B. Otto and Kathleen Wheeley Award
for Excellence in Technology Transfer to Edward Chaum, MD, PhD, Plough Foundation Professor of Retinal
Diseases. The award is a cash prize given to a member of the UT faculty who has had a major impact on the
tech transfer success of the university. Dr. Chaum has been at the UT Health Science Center since July 2000. He
has received four issued patents with several others pending, authored more than 60 peer-reviewed publications
and directed more than $8 million in sponsored research projects at UTHSC.
In 2007, Dr. Chaum founded Hubble Telemedical, a company that enables screening and diagnosis of
retinal diseases in non-specialty settings through their proprietary, award-winning Telemedical Retinal Image
Analysis and Diagnosis (TRIAD™) technology. Dr. Chaum is also the founder of Nanophthalmics, a medical
device company developing nano-engineered surgical instruments for ophthalmic surgery, and Infusense, a
medical device company developing an automated infusion platform for the anesthetic agent propofol.
“Dr. Chaum is the type of faculty member with which technology transfer offices dream to work,” Magid said.
“Ed’s successful track record in basic and translational research speaks for itself. The three companies he’s founded
in the past five years demonstrate that he is also a skilled entrepreneur. He exemplifies the characteristics that Otto
and Kathleen Wheeley sought to recognize when they endowed the Award for Excellence in Technology Transfer at
the University of Tennessee.”
Medicine Summer 2014 43
Students
On Friday, March 21, 2014, 154 UTHSC College of Medicine students gathered
with family and friends at the Pink Palace Museum in Memphis to celebrate Match
Day. Dr. David Stern, dean of the College of Medicine addressed the crowd stating,
“Congratulations to all of you. I am excited for the future as you are the people that
will change the face of medicine.”
At noon, the class of 2014 simultaneously opened the
envelopes containing their match information, and cheers
erupted. The UTHSC Alumni Office was on hand with
an oversized map that allowed the students to pin their
residency location.
Forty-four percent of the class matched within the UT system.
Fifty percent of the class matched in to a primary care specialty.
44
*Includes Baptist Hospital-Nashville, Baptist Memorial Hospital, Campbell Clinic, Le Bonheur Children’s Hospital, Methodist University Hospital,
Saint Francis Hospital, Region One Health, Memphis VA Medical Center, UT Program-Jackson and UT/Methodist
**East Tennessee State University, Vanderbilt University Medical Center, Other
Medicine
Medicine Summer 2014 45
Students
A R E A S O F S P E C I A LT Y
Class of 2014 Residency Placement List
Zachary Richard
Abramson
UTHSC College of Medicine, Memphis
Baptist Memorial Hospital, Tenn.
Medicine-Preliminary
Radiology-Diagnostic
Suneeta Kumari Acharya
UTHSC Graduate School of Medicine,
Knoxville
Anesthesiology
Cyrus McCoy Adams
Vanderbilt University Medical Center,
Tenn.
Vanderbilt University Medical Center,
Tenn.
Surgery-Preliminary
Others (Non-Primary Care)****
*Family Medicine, Internal Medicine, Internal Medicine-Primary, Medicine/Pediatrics, Obstetrics-Gynecology, Pediatrics
**Medicine-Preliminary, Surgery-Preliminary, Transitional Year
***General Surgery, Neurological Surgery, Ophthalmology, Orthopaedic Surgery, Otolaryngology, Plastic Surgery, Urology
****Anesthesiology, Dermatology, Emergency Medicine, Neurodevelopmental Disabilities, Neurology, Pathology-Anatomic/Clinical, Physical Medicine & Rehab, Psychiatry, Radiation-Oncology, Radiology-Diagnostic
Laura Nicole Grese
UTHSC College of Medicine, Memphis
ObstetricsGynecology
Christopher Michael
Knight
UTHSC College of Medicine,
Memphis/Jackson
Family Medicine
Charles Maurice
Groeschell
UTHSC College of Medicine, Memphis
Internal Medicine
Tyler Harrison Koestner
UTHSC College of Medicine, Chattanooga
General Surgery
Audrey Kathleen
Christiansen
Case Western/University Hospitals
Case Medical Center
Pediatrics
Alexander H. Habashy
Ochsner Clinic Foundation, La.
Orthopaedic Surgery
Nancy Kuo
Delayed Residency
Internal Medicine
University of Texas Southwestern
Medical School, Dallas
Pediatrics
Vanderbilt University Medical Center,
Tenn.
Transitional Year
Lauren Kylie Lazar
Charles Amos Clark
Providence Hospital, Mich.
Urology
Makida Tesfaye
Hailemariam
Providence Hospital, Mich.
Radiology-Diagnostic
Jacob Richard Lepard
Emergency Medicine
University of Kentucky Medical Center
Obstetrics-Gynecology
Andrew Martin Hall
UTHSC College of Medicine, Memphis
Jackson Memorial Hospital, Fla.
Transitional Year
Anesthesiology
University of Alabama Medical Center,
Birmingham
Neurological Surgery
Patrick Albert Cleeton
Jordan Nicole Halsey
Rutgers-New Jersey Medical School
Plastic Surgery
(Integrated)
Thomas B. Hamilton
University Hospitals, Jackson, Miss.
Anesthesiology
Michael Phillip Hancock
UTHSC College of Medicine, Memphis
Internal Medicine
Jensen Ellen Hart
UTHSC College of Medicine, Chattanooga
Internal Medicine
William Tyler Hayden
UTHSC College of Medicine, Chattanooga
Emergency Medicine
William Austin Hester III
Tulane University School of Medicine, La.
Sarah Mabrey Heston
Frank Hamilton
Anderson, IV
Delayed Residency
Tucker W. Anderson
UTHSC College of Medicine, Memphis
Pediatrics
Olusegun Oluwaseun
Aranmolate
Vidant Medical Center/East Carolina
University, N.C.
General Surgery
Lindsay Flynn Arnold
University of Louisville School
of Medicine, Ky.
General Surgery
Christopher Lynn Atwell
UTHSC College of Medicine, Memphis
Internal Medicine
Hilda E. Azabache Orrillo
University of Louisville School
of Medicine, Ky.
Internal Medicine
Joshua Nissi Christian
Bakke
UTHSC College of Medicine, Memphis
Pediatrics
Renee Amelia Barnes
UTHSC College of Medicine,
Memphis/Saint Francis
Family Medicine
Oran Alvin Basel
St. Thomas Midtown Hospital, Tenn.
Internal Medicine
John William Bodford
University of Texas Southwestern
Medical School, Dallas
Emergency Medicine
Cody Bogema
UTHSC College of Medicine, Memphis
Medicine-Pediatrics
Vandana Botta
UTHSC College of Medicine, Memphis
Surgery-Preliminary
Andrew Bradley Boucher
Emory University School of Medicine, Ga.
Neurological Surgery
Erik Craig Bowman
University of Nebraska Affiliated Hospitals Orthopaedic Surgery
Joseph James Boyd
UTHSC College of Medicine, Memphis
Surgery-Preliminary
Allen Clay Brown
University of South Florida College
of Medicine, Tampa
Internal Medicine
Clifford Scott Brown
Duke University Medical Center, N.C.
Otolaryngology
Gregory J. Burana
UTHSC College of Medicine, Memphis
Obstetrics-Gynecology
Tyler Wilson Clemmensen University of Alabama Medical Center,
Birmingham
Pathology
Peter Coulson
Transitional Year
Austin Robert Davidson
UTHSC Graduate School of Medicine,
Knoxville
UTHSC Graduate School of Medicine,
Knoxville
UTHSC College of Medicine, Memphis
Radiology-Diagnostic
Orthopaedic Surgery
UTHSC College of Medicine, Memphis
UPMC Medical Education, Pa.
Medicine-Preliminary
Radiology-Diagnostic
Kenetra Modessa Hix
St. Louis University School of
Medicine, Mo.
Family Medicine
Adnan Dervishi
University of Louisville School
of Medicine, Ky.
University of Louisville School
of Medicine, Ky.
Surgery-Preliminary
Andrew Parrish Holt
UTHSC College of Medicine, Memphis
Medicine-Pediatrics
Jonathan Andrew Holt
UTHSC College of Medicine, Memphis
Medicine-Preliminary
Jarad Lee Hopper
UTHSC College of Medicine, Memphis
Sumaiya Amena Hossain
Delayed Residency
Kaitlin Ridder Jaqua
Internal Medicine
Whitman Scott Dowlen
Vidant Medical Center/East Carolina
University, N.C.
Emergency Medicine
Hannah Menefee Dudney Vanderbilt University Medical Center,
Tenn.
Obstetrics-Gynecology
Mallory A. Duncan
University of Texas Health Science Center, General Surgery
San Antonio
Terence Sean Dunn
University of Alabama Medical Center,
Birmingham
Internal Medicine
Carolinas Medical Center, N.C.
Obstetrics-Gynecology
Emily Rose Earles
Samuel Ray Marcrom
Baptist Health System, Ala.
University of Alabama Medical Center,
Birmingham
Transitional Year
Radiation-Oncology
Internal Medicine
Steven James Massaro
UTHSC Graduate School of Medicine,
Knoxville
Anesthesiology
Indiana University School of Medicine
Indiana University School of Medicine
Surgery-Preliminary
Urology
Patrick David McFarland
UTHSC Graduate School of Medicine,
Knoxville
Anesthesiology
John Brian Jasper
UTHSC College of Medicine, Memphis
Internal Medicine
Kristen Lea Jeffreys
Cincinnati Children’s Hospital MC, Ohio
Pediatrics
Heather Elaine Jeffries
University of Cincinnati Medical
Center, Ohio
Obstetrics-Gynecology
Patrick William Jennings
UTHSC College of Medicine, Memphis
Surgery-Preliminary
Jonathan Robert Jerkins
UTHSC College of Medicine, Memphis
Pediatrics
Michael Gerald Jerkins
University of Cincinnati Medical
Center, Ohio
Medicine-Pediatrics
Leah Ann John
UTHSC College of Medicine, Memphis
Transitional Year
Benjamin Allen Jones
Christ Community Health Services, Tenn.
Family Medicine
Mark Taylor Jones
UTHSC College of Medicine, Chattanooga
Internal Medicine
UTHSC College of Medicine, Memphis
University of Virginia
Medicine-Preliminary
Radiology-Diagnostic
Aaron Michael Evans
Baylor College of Medicine, Houston, Texas Internal Medicine
Ludwig Ivan Francillon
UTHSC College of Medicine, Memphis
Obstetrics-Gynecology
Eugene Chul Kang
Exempla St. Joseph Hospital, Colo.
Surgery-Preliminary
Sherie Nicole Byrd
UTHSC College of Medicine, Memphis
Pediatrics
Donald Benjamin Franklin UTHSC College of Medicine, Memphis
Orthopaedic Surgery
Sneha Kemkar
Pediatrics
John Martin Cassidy
UTHSC College of Medicine, Memphis
Internal Medicine
Ashada Freshwater
Family Medicine
Samuel Nelson Che
Casales
North Mississippi Medical Center
Family Medicine
UTHSC College of Medicine,
Memphis/Jackson
University of California, Irvine Medical
Center, Calif.
Ghaila Chinasa Keng
Internal Medicine
UTHSC College of Medicine, Chattanooga
Internal Medicine
University of Nevada Affiliated Hospitals,
Las Vegas
Scott Jordan Galloway
Internal Medicine
University of New Mexico School
of Medicine
Internal Medicine
Robert Brian Burress
SAUSHEC-Brooke Army Medical Center,
Texas
Medicine-Preliminary
Radiology-Diagnostic
Benjamin James Maddox St. Thomas Midtown Hospital, Tenn.
Emergency Medicine
Ellis Rupert Easterling
UTHSC College of Medicine, Memphis
Massachusetts General Hospital
Internal Medicine
James Davis
UTHSC Graduate School of Medicine,
Knoxville
Weier Li
Kristen Lea Lytle
Internal Medicine
Joshua Wayne Donegan
Radiology-Diagnostic
Pediatrics
University of Alabama Medical Center,
Birmingham
Internal Medicine
Mayo School of Graduate Medical
Education, Fla.
UTHSC College of Medicine, Memphis
Ellen Elizabeth Davis
UTHSC College of Medicine, Chattanooga
Jacob Ian Lewis
Orthopaedic Surgery
General Surgery
Amirtha Dileepan
Pediatrics
Surgery-Preliminary
Radiology-Diagnostic
Jesse Thornhill Davidson Barnes-Jewish Hospital, Mo.
Urology
Bryauna Schunece Lewis University of Alabama Medical Center,
Birmingham
Andrew Harrison Lichliter UTHSC College of Medicine, Chattanooga
Baylor University Medical Center,
Dallas, Texas
University of Alabama Medical Center,
Birmingham
46
Surgery***
Peds-Prelim/Child
Neurology
Neurodevelopmental
Disabilities
Mount Sinai Beth Israel
Samuel Lucas Burleson
One Year Programs**
Our Lady of the Lake Regional
Medical Center, La.
Johns Hopkins Hospital, Md.
Maritza Nicole Aitken
Eric Michael Chin
Primary Care*
Jenna Elizabeth McKinnie Ochsner Clinic Foundation, La.
Anesthesiology
Marissa Mencio
UTHSC College of Medicine, Chattanooga
Surgery-Preliminary
Meredith Metcalf
University of Missouri, Kansas City
Programs
University of Kansas Medical Center,
Kansas City
Surgery-Preliminary
Amanda Leshae Miller
UTHSC College of Medicine,
Memphis/Saint Francis
Family Medicine
Robert Hines Mitchell
University of Utah Affiliated Hospitals
Internal Medicine
Clare Murphy
UTHSC College of Medicine, Chattanooga
Baptist Memorial Hospital, Tenn.
Transitional Year
Radiology-Diagnostic
Daniel Sallis Murrell
University of Illinois College of Medicine,
Chicago
Internal Medicine
Zachary Paul Nahmias
Beth Israel Deaconess Medical Center,
Mass.
Barnes-Jewish Hospital, Mo.
Medicine-Preliminary
St. Louis University School of
Medicine, Mo.
Emergency Medicine
Michael Nyarko Ofori
Urology
Dermatology
Medicine Summer 2014 47
Students
2014 Medical Student Research Poster Session
Class of 2014 Residency Placement List (Continued)
Wayne Joseph Overman
Baptist Health System, Ala.
Boston University Medical Center, Mass.
Transitional Year
Dermatology
Faisal Shaikh
NYP Hospital-Weill Cornell
Medical Center, N.Y.
Internal Medicine
Brennan Elizabeth
Palazola
UTHSC College of Medicine, Memphis
Internal Medicine
Jacolby John Short
Medicine-Preliminary
Dilan Anil Patel
Barnes-Jewish Hospital, Mo.
Internal Medicine
Virginia Commonwealth University
Health System
University of Louisville School
of Medicine, Ky.
Jaclyn Halley Pearson
UTHSC College of Medicine, Memphis
Internal Medicine
Abigail Lynn Smith
Pediatrics
Donald Lee Pierce
Rhode Island Hospital/Brown University
Peds/Psych/Child
Psych
Walter Reed Military Medical Center,
Bethesda, MD
Andrew Beck Sneed
Andrew Stephen Poole
Greenville Hospital System/University
of South Carolina
Orthopaedic Surgery
UTHSC College of Medicine, Memphis
University of Alabama Medical Center,
Birmingham
Medicine-Preliminary
Radiology-Diagnostic
Jordan Stanislaw Pyda
Beth Israel Deaconess Medical Center, Mass. General Surgery
Kristen A. Stancher
Internal Medicine
Arifur Naved Rahman
UTHSC College of Medicine, Memphis
University of Illinois College of Medicine,
Chicago
Medicine-Preliminary
RadiologyDiagnostic/UIC
UTHSC Graduate School of Medicine,
Knoxville
Matthew Kurtis Stein
UTHSC College of Medicine, Memphis
Internal Medicine
Douglas Ryan Taylor
UTHSC College of Medicine, Memphis
Neurological Surgery
Karen Rhea
University of Alabama Medical Center,
Birmingham
Internal Medicine
Wissam S. Tobea
University of Oklahoma College
of Medicine, Okla. City
Anesthesiology
Cody Robert Richardson
UTHSC College of Medicine, Memphis
UTHSC College of Medicine, Memphis
Transitional Year
Ophthalmology
Brandon Lee Todd
University of Virginia
Medicine-Primary
Alexandria Tran
UTHSC College of Medicine, Memphis
Internal Medicine
Rebecca Shelley Weller
Richardson
UTHSC College of Medicine, Memphis
UTHSC College of Medicine, Memphis
Transitional Year
Radiology-Diagostic
Christina Brown Tran
UTHSC College of Medicine, Memphis/STF
Family Medicine
Samuel James Riney
UTHSC College of Medicine, Memphis
Internal Medicine
Drew Bedford Turner
UTHSC College of Medicine, Memphis
General Surgery
Quantel Valdezzel Rolle
UTHSC College of Medicine, Chattanooga
Surgery-Preliminary
Ana Luisa Valente
Ochsner Clinic Foundation, La.
Obstetrics-Gynecology
Daniel John Roubik
William Beaumont Army Medical Center,
Texas
General Surgery
Vicky Elise Ruleman
LSU School of Medicine, New Orleans, La. Pediatrics
Sara Jane Rutter
Yale-New Haven Hospital, Conn.
Pathology/CombAnat & Clin
Maanasi Samant
Barnes-Jewish Hospital, Mo.
Internal Medicine
Evan Ross Sander
Childrens Hospital, Los Angeles, Calif.
Pediatrics
Ramy Medhat Sayed
University of Missouri, Kansas City
Programs
Medicine-Pediatrics
College of Medicine co-sponsored the annual poster session.
With a motto of “Be Worthy to Serve the Suffering,” Alpha Omega
Alpha is a national honor society for medical students founded in 1900.
For more information, go to www.alphaomegaalpha.org.
Radiology-Diagnostic
Mauricio Omar Valenzuela University of South Florida College
of Medicine, Tampa
Internal Medicine
Albert Russell Vaughn
UTHSC College of Medicine, Memphis
Medicine-Pediatrics
Cory A. Vaughn
University of Arkansas, Little Rock
Otolaryngology
Yuefeng Wang
UTHSC College of Medicine, Memphis
University Hospitals, Jackson, Miss.
Medicine-Preliminary
Radiation Oncology
Megan Delores Ward
Temple University Hospital, Pa.
Internal Medicine
Ryan Ward
Summa Health/NEOMED, Ohio
Cleveland Clinic Foundation, Ohio
Medicine-Preliminary
Radiology-Diagnostic
Michael Cody Scarbrough Ochsner Clinic Foundation, La.
Anesthesiology
Joshua Brandon Wasmund Navy Medical Center, San Diego, Calif.
General Surgery
Charles William Schlappi
University of Alabama Medical Center,
Birmingham
Pediatrics
Allison Noel Watts
UTHSC College of Medicine, Memphis
Dermatology
David Harrison Wheeler
UTHSC College of Medicine, Memphis
Internal Medicine
John M. Schmidt
UTHSC College of Medicine, Memphis
Carolinas Medical Center, N.C.
Surgery-Preliminary
Phys Medicine &
Rehab
Gregory Shane White
University of North Carolina Hospitals
Internal Medicine
Martha Angela Wilcox
University of Arkansas, Little Rock
Neurological Surgery
Benjamin Hugh Schoepke University of Washington
Affiliated Hospitals
Anesthesiology
Lorna Rosemarie Wilks
Baylor College of Medicine, Houston, Texas Psychiatry
Julie Lynn Worthington
UTHSC College of Medicine, Chattanooga
Surgery-Preliminary
Dawn Elizabeth Scott
Vidant Medical Center/East Carolina
University, N.C.
Pediatrics
Matthew Allen Wynne
UTHSC College of Medicine,
Memphis/Jackson
Family Medicine
Christine Jeannette
Secrest
Medical College of Georgia
Obstetrics-Gynecology
Baogang Xu
UTHSC College of Medicine, Memphis
Baptist Memorial Hospital, Tenn.
Medicine-Preliminary
Radiology-Diagnostic
Michael Yaoyao Yin
Emory University School of Medicine, Ga.
Internal Medicine
48
A
pproximately 25 students from UTHSC’s College of Medicine – M2s,
M3s and M4s – presented the results of their various research projects
on Feb. 28 in the lobby of the 920 Madison Avenue building. The Beta
Tennessee chapter of the Alpha Omega Alpha Honor Society and the UTHSC
Kathleen Kern explains the results of her study,
“Opioid Misuse Behaviors in Adolescents and
Young Adults in a Hematology Oncology Institution,”
to Gerald Presbury, MD. She is an M2 whose
undergraduate work was at Vanderbilt University.
Her study retrospectively analyzed a
new assessment tool, the Screener for Opioid
Aberrant Behavior (SOABR) checklist, to examine
correlates of aberrant opioid behavior (AOB) in
a group of adolescent oncology and hematology
patients who received chronic opioid therapy. The
conclusion was that adolescent and young adult
cancer patients may exhibit AOB despite having a
legitimate source of pain. Therefore, a screening
tool such as SOABR would be beneficial to
prescribing physicians and multidisciplinary teams.
Polina Varavva Zmijewski explains her study, titled,
“Detection of key signaling molecules following treatment
with OSI-906 in Pediatric Adrenocortical Carcinoma.”
She is a native of Odessa, Ukraine, an M2 and a
graduate of Barnard College of Columbia University.
Pediatric Adrenocortical Carcinoma is a highly
aggressive malignancy for which the standard
treatment has limited efficacy. This study, made
possible by ALSAC (American Lebanese Syrian
Associated Charities) at St. Jude, aimed to determine
the ability of the IGF-1R inhibitor Listinib to bind to its
target receptor and dampen downstream signaling
effects responsible for tumor growth.
M2 Keith Nord, right, discusses “A Nanomedicine
Approach for Inhibition of NFKB in Treatment of
Osteoarthritis” with Nelson Strother, assistant dean of the
College of Medicine for Admissions and Student Affairs.
Osteoarthritis (OA) is a leading cause of disability in
the United States. This study’s objective was to analyze
the efficacy of three substances – a NEMO-bindingdomain peptide (NBD), vitamin D3 and a non-calcemic
analog of vitamin D – to inhibit NFKappaB, a key activator
of the collagen breakdown process, as a means of
preventing OA. The data provided strong support for the
efficacy of these agents as potential therapeutic agents
in the treatment of arthritis.
M2 Scott Marbry discusses his study, “Tetrospanin CD9
Regulates Cell Contraction and Actin Arrangement via
RhoA in Human Aortic Smooth Muscle Cells” with Vicki
Park, PhD. The study was made possible by a grant from
the American Heart Association.
M2 Mercy Kibe explains “Identification of a Small
Cohort of Genes Expressed in Primary Uveal Melanoma
Cells that Become Metastatic.”
Uveal melanoma, the most common primary
intraocular cancer in adults, metastasizes, mainly to the
liver, in 50 percent of patients who develop it, but the
mechanisms that govern this remain unclear. In this study,
targeted PCR arrays were used to identify genes that might
drive metastases and target them for further therapy.
Daniel Sharbel, right, talks with Larry Nichols, MD.
Sharbel is an M2 with an undergraduate degree
from the University of Georgia. His study, “Smad4
Loss in Murine Colonic Epithelium Disrupts Intestinal
Homeostasis,” focused on the role of Smad4, the
loss of which occurs in more than 50 percent of
colorectal cancers. This loss impacts the intestinal
epithelium, causing the Transforming Growth FactorBeta (TGF-Beta)/Bone Morphogenic Protein (BMP)
signaling pathway to be inactivated in 50-75 percent of
colorectal cancers, but how it does so has not been fully
elucidated. This study sought to understand the role of
Smad4 in normal intestinal homeostasis as well as how
its loss leads tumorigenesis.
Kate Snowden, left, discusses her research, titled,
“Pseudomonas aeruginosa Adherence to Adenoid
Tissue,” with Suzanne Satterfield, MD, DrPH. Snowden
is an M2 student with an undergraduate degree from
Vanderbilt University.
The goal of the study was to determine if
Pseudomonas aeruginosa adhered to adenoids from
patients diagnosed with recurrent acute otitis media,
chronic otitis media with effusion, or obstructive
sleep apnea. Snowden’s research team sought
to determine if these conditions play a larger role
in the emergence of Pseudomonas aeruginosa
chronic respiratory colonization and infection. A
green fluorescent protein (GFP) was used to tag
Pseudomonas aeruginosa for a two hour assay.
The result was that levels of GFP across all three
diagnostic groups were not different when analyzed
by either flow cytometry or Western blotting.
Medicine Summer 2014 49
Students
The
Class Notes
U
STUDENT
A Profile of the 2013
College of Medicine
Entering Class
Number of Applications............................................................1628
Number of Applicants Interviewed............................................... 501
New Enrollees ..........................................................................165
Male ..........................................................................................93
Female........................................................................................72
Average Age................................................................................23
Age Range.............................................................................20-32
Underrepresented Minority.....................................................12.7%
Colleges Attended........................................................................ 67
Academic Credentials
Average MCAT*
Tuition & Fees (2013-14)
3.52 Science GPA
3.60 Overall GPA
Verbal Reasoning.................................... 10
Physical Sciences................................... 10
Writing Sample......................................... 0
Biological Sciences................................. 10
Residents.............................. $31,432
Nonresidents......................... $62,292
Boston Strong
Meets
Volunteer Power
J
ohn Little, MD, proudly wore the
University of Tennessee orange and
represented the medical college well
by racing impressively in the 2014 Boston
Marathon. He is an avid runner who called
the marathon “the experience of a lifetime.”
Dr. Little graduated from the College of
Medicine in 1992 and is director of the
Pediatric Cochlear Implant Program at
Children’s Hospital in Knoxville. He is also
a member of the college’s Alumni Council.
*All took the MCAT. 100% had baccalaureate degrees.
Undergraduate Schools Attended by New Enrollees
Asbury University
Auburn University
Austin Peay State University
Belmont University
Birmingham Southern College
Bowdoin College
Brigham Young University
Bryan College
Carleton College
Carnegie Mellon University
Carson-Newman College
Christian Brothers University
Clayton State University
Clemson University
College of the Ozarks
Colorado College
Colorado State University
Cornell University
Dartmouth College
DePauw University
Duke University
East Tennessee State University
50
Emory University
Furman University
Grove City College
Harvard University
Indiana University Bloomington
John Hopkins University
Lee University
Lipscomb University
Marshall University
Maryville College
Middle Tennessee State University
Middlebury College
Mississippi State University
Princeton University
Rhodes College
Saint Louis University
Samford University
Southern Adventist University
Stanford University
Tennessee State University
United States Military Academy
Tennessee Tech University
The University of Memphis
The University of the South
Tulane University
UNC at Chapel Hill
Union University
UT Chattanooga
UT Knoxville
UT Martin
University of Alabama
University of California-Berkeley
University of Chicago
University of Miami
University of Mississippi
University of Notre Dame
University of Pennsylvania
University of Virginia
Vanderbilt University
Wake Forest University
Warren Wilson College
Washington-Lee University
Washington University-Saint Louis
Wheaton College
Yale University
J
John Jennings, MD, Becomes President of American
Congress of Obstetricians and Gynecologists
ohn C. Jennings, MD, of League City, Texas, became the
65th president of the American Congress of Obstetricians
and Gynecologists (ACOG), based in Washington, D.C.
Dr. Jennings completed his medical degree and his residency
at the University of Tennessee in Memphis. He is currently
professor of obstetrics and gynecology at the Texas Tech
University Health Sciences Center at the Permian Basin.
The ACOG is the nation’s leading group of physicians providing
health care for women. As a private, voluntary, nonprofit organization
of more than 58,000 members, the ACOG strongly advocates for
quality health care for women, maintains the highest standards of
clinical practice and continuing education of its members, promotes
patient education, and increases awareness among its members and
the public of the changing issues facing women’s health care.
Medicine Summer 2014 51
UTHSC in the Media
In Memoriam
1943
W. Byron Inmon, MD, age 94,
of Madison, Miss., died Jan. 8, 2014.
Dr. Inmon was especially gifted in gynecological
surgery, and his work is cited in textbooks and
other publications. He was a founding member
of the Society of Gynecological Surgeons.
1945
William Matthew Featherston, MD, age 91,
of Elk City, Okla., died Dec. 1, 2013.
Dr. Featherston established his practice in
Elk City in 1949, and also provided several
clinics in the Tehucan, Mexico, area. He has
been inducted in the Western Oklahoma
Hall of Fame.
Melton Price Meek, MD, age 91,
of Lawton, Okla., died April 16, 2014.
Dr. Meek was a member of Phi Chi Medical
Fraternity, an alumnus of the Seymour
A. Mynders Fraternity, a Diplomate of the
American Board of Pediatrics, a Fellow of the
American Academy of Pediatrics, a member
of the American Medical Association, a
past president of the Comanche-Cotton and
Tillman Counties Medical Society, a past
Chief of Staff of Comanche County Memorial
Hospital, a member of the Southwest
Oklahoma Genealogical Society and a past
president of the Lawton Philharmonic Society.
1946
Lee Watson Milford, Jr., MD, age 91,
of Memphis, Tenn., died Nov. 22, 2013.
Recognized as one of the world’s leading
hand surgeons and a pioneer in that field, he
wrote one of the few definitive texts on hand
surgery, which he illustrated with his own color
photos. It went through multiple printings and
was published in four languages. Dr. Milford
mentored and trained many aspiring hand
surgeons from the United States and around the
globe. These became the “Milford Hand Club.”
Sidney Ely Daffin, MD, age 91,
of Panama City, Fla., died Dec. 6, 2013.
Dr. Daffin opened his practice in Family
Medicine in 1950. Over the next 25 years, he
dedicated himself to serving his patients and
the community. After closing his practice
downtown, he worked in the General Medical
Clinic at Tyndall Air Force Base for 10 years.
He finished his medical career as director of
Washington County Public Health.
1947
Hoyt C. Harris, MD, age 93,
of McMinnville, Tenn., died Oct. 23, 2013.
In his spare time, Dr. Harris earned a
law degree in the mid-1960s from LaSalle
University of Chicago. His memoir, “A Steep
Climb,” was published in 2010. The book,
in addition to relating a long, eventful life
of highs and lows, recounts growing up on
a rural farm and how plowing many acres
behind a very stubborn mule made him
adamantly aspire to one day get off the
farm and become a physician.
1952
Coulter S. Young, MD, age 89,
of Manchester, Tenn., died March 25, 2014.
Dr. Young was a fellow of the American
Academy of Family Physicians, a Diplomate of
the American Board of Family Practice, and a
member of the American Medical Association,
and the Tennessee Medical Association. He
was instrumental in establishing the Coffee
County Medical Society.
1953
Jim F. Sharp, MD, age 66,
of Louisville, Ky., died Nov. 8, 2013.
Dr. Sharp started his career as a Navy flight
surgeon and met his future wife Janet when
he was stationed in Okinawa, Japan.
1954
John Hamilton Edmonson, MD, age 82,
of Rochester, Minn., died Nov. 23, 2013.
Dr. Edmonson worked at the Mayo Clinic
Dept. of Medical Oncology until his
retirement in 2001. At Mayo, he became a
Mayo Medical School Professor of Oncology.
Over his career, he was awarded an
abundance of research grants, and authored
approximately 200 scientific papers, abstracts
and book chapters. He belonged to many
regional and national oncology research
groups, and was on the editorial board for
the Surgical Gynecologic Oncology Journal.
1956
Frederick Duke Lansford, MD, age 87,
of Chattanooga, Tenn., died Oct. 14, 2013.
Dr. Lansford obtained additional training
at Erlanger Hospital where he later taught
as an associate clinical professor in Family
Medicine. He was board certified by the
American Academy of Family Physicians
and was a member of the active staff of East
Ridge Hospital, Erlanger Hospital, Parkridge
Hospital and Memorial Hospital.
Fletcher Howard Goode, MD, age 83,
of Memphis, Tenn., died Nov. 17, 2013.
Along with his practice, he was an associate
professor of Ophthalmology at UTHSC
and was on the staff at St. Jude Children’s
Research Hospital. UT Medical School
recognized Fletcher with a Distinguished
Alumnus Award in 1996.
Emmett Bell, Jr., MD, age 90,
of Memphis, Tenn., died Nov. 20, 2013.
Dr. Bell held many leadership positions at
Le Bonheur Children’s Hospital, including
chief of medicine, chief of staff, chair of the
Credentialing Committee, member of the
Medical Ethics Committee, and consultant for
the Division of Cardiology. Dr. Bell also served
on the University of Tennessee faculty.
1957
Richard Grossman, MD, age 81, of
Thousand Oaks, Calif., died March 13, 2014.
Dr. Grossman was a renowned plastic and
reconstructive surgeon who pioneered the
comprehensive care of burn patients. In
the late 1960s, Dr. Grossman persuaded
administrators at Sherman Oaks Hospital
in California to set aside two beds for burn
patients. By 1978, the ward was the nation’s
largest private burn-treatment center. On
the facility’s 25th anniversary, it was named
the Grossman Burn Center at Sherman
Oaks Hospital in honor of the surgeon who
pioneered its cutting-edge care. One of
Grossman’s more celebrated patients was
comedian Richard Pryor, who spent six
weeks at the center in 1980 after suffering
third-degree burns over 50 percent of his
body in a fire at his home.
1989
Catherine L. Jenkins, MD, age 56,
of Columbus, Ohio, died Jan. 3, 2014.
She graduated from East Tennessee State
University in 1984 with a BS in biology before
attending the UT College of Medicine. She
completed her residency in pediatrics at
Children’s Hospital in Columbus, prior to
joining Pediatric Associates.
Francis Jones, MD, age 91, of Knoxville, Tenn., died Oct. 14, 2013.
Dr. Jones was the first pathologist and director of Clinical Laboratories of the UT Hospital in Knoxville when it opened
and the inaugural chair to the Department of Pathology at the Graduate School of Medicine when it was formed in 1969.
52
The Stroke
Strike Force
The Commercial Appeal, The Daily News and the Memphis Business
Journal tell the tale of a new department chairman’s innovative plan
to combat strokes.
Bringing
Up Baby
The Commercial Appeal, USA Today, Pregnancy & Newborn Magazine,
Fox & Friends and thebump.com report on an assistant professor’s
book about improving child development the old-fashioned way.
Save Your
Skin
The Commercial Appeal
The Daily News
Memphis Business Journal
The Commercial Appeal
USA Today
Pregnancy & Newborn
Magazine
Fox & Friends
thebump.com
The Commercial Appeal
Fox 13
The chairman of the Kaplan-Amonette Dermatology Department offers
advice on protecting your skin from skin cancer in The Commercial
Appeal and on Fox 13.
Rising
Vapors
A UTHSC professor weighs in on the growing popularity of electronic
cigarettes in The Daily News and on WREG and Local 24.
The Daily News
WREG
Local 24
Groundbreaking research, first-class education, superior clinical care, and dedicated public service —
UTHSC is making news 24/7, and the world is helping us tell our story. For a look at what the local,
national and international media are saying about UTHSC, go to news.uthsc.edu/in-the-media.
Medicine Summer
Summer 2014
2014 53
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Medicine
Nonprofit Org.
The University of Tennessee Health Science Center
Office of Development and Alumni Affairs
62 S. Dunlap, Suite 420
Memphis, Tennessee 38163
CHANGE SERVICE REQUESTED
Save the Date
August 14 - 17, 2014
2014 Medicine Alumni Weekend
Oct 15 - 17, 2014
Memphis, Tennessee
Golden Graduate Homecoming
Honoring the Class of 1964
(plus all previous Golden Graduates invited)
Details to be mailed soon!
Oct 24, 2014
Knoxville, Tennessee
College of Medicine Alumni Reception
See page 36
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U.S. Postage
PAID
Memphis, TN
Permit No. 4026