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RHO CHI EVENTS ....... 1 Issue 2 CURRENT EVENTS ...... 3 ALUMNI PROFILE ........ 5 VOLUME 5 April 2014 The NU Pharmacist The Rho Chi Beta Tau Chapter Newsletter Uswa Ahmad, Newsletter Chair Angela Fu, Secretary Alessandra Lyman, Member Kerri Roach, Member Dr. Michael Gonyeau, Editor Pharmacy Auction Written by Alessandra Lyman Photos by Yung-en Fung The Rho Chi Beta Tau chapter at Northeastern held its first annual Pharmacy Auction this March. All proceeds benefited the School of Pharmacy Relay for Life team. Rho Chi raised an incredible $1,400 by auctioning off events offered by both students and faculty to foster fellowship, collaboration, and communication among those in the pharmacy profession. Each participant came up with an event to auction off to a pharmacy student where they could discuss career goals, classes, work, applying to residencies or fellowships, or get to know the person better in a non-academic setting. Some of the events included being “Dean for a Day” and shadowing Dean Reynolds, with the added bonus of coming up with a new policy or idea to implement immediately in one of the pharmacy classes, as well as coffee, lunch, dinner, and even “a race to breakfast” where students could sit down with potential preceptors to discuss the future. The event was hosted by Jessie Signorelli and Ali Lyman, who had a great time poking fun at faculty and students according to a questionnaire they filled out prior to the auction with things such as “one thing students and peers may not know about me is __,” and “if I could describe myself in one word it would be ___.” The event brought a sense of community to the School of Pharmacy and was a night full of entertainment, personality, laughs, and compassion for a great cause. In addition to the amazing turnout and support the auction received at Northeastern, shortly after it occurred the chapter was notified that for the second year in a row, we received a Project Proposal Award from the national office during the society’s annual meeting in Orlando, Florida. This is a tremendous honor and shows the hard work, determination, creativity, and drive that the members of our chapter possess. It is great to be recognized, as it was the highlight of the year for the current Rho Chi chapter. We thank all of the professors and students who auctioned off events, as well as those who bid to help raise an amazing amount of money to fight cancer. We also want to thank our advisor, Dr. Gonyeau, and Dean Reynolds for commenting on the written proposal and helping to organize the event, as well as Jessie Signorelli, Chair of the Pharmacy Auction Committee, for all her hard work planning, organizing, and executing this successful endeavor. Congratulations to all of those involved for yet another stellar event and award for the Northeastern Pharmacy Program! Professional Speed Dating Written by Kerri Roach, Photos by Yung-en Fung Kaylee Marino, Dr. Kelly Macedo, Dr. Victoria Caccioppoli, and Dr. Chuck Berds who provided students with information regarding the pharmaceutical/ biotechnology industry, fellowships, psychiatric pharmacy, ambulatory care, social and administrative sciences, residencies, and leadership and involvement during their time at Northeastern. In addition to our wonderful pharmacist speakers, Christopher Campbell, Chelsea Binkowski, Benjamin Hohlfelder, Xander Allewell, Aanal Desai, and Jade Hoang participated as P4 students who educated younger students on residenOn March 18, the Beta Tau chapter hosted cies, fellowships, research, hospital pharmacy, and academics. its second annual Professional Speed Dating After the speed dating rounds ended, event. Last year, our chapter won a Project Prosome students stayed for a networking posal Award at the 2013 national Rho Chi session with the speakers. Many students meeting at the APhA annual meeting. More were thrilled to have the chance to exthan seventy students signed up for this year’s event, during which they had the opportunity to plore different career paths in the pharmacy profession and to have the opportuhear from five speakers in small groups. The nity to talk with successful pharmacists event was very similar to last year’s with five rounds of ten-minute discussions. The Beta Tau and students about how to get to the positions they want. Students particularly chapter was lucky to have Dr. Annie Partisano, commented on the ability to learn about Dr. Christina Gallagher, Dr. Mark Watanabe, career opportunities that they had less Dr. Michele Jacobs, Dr. Dave Zgarrick, Dr. exposure to throughout their schooling, such as industry and fellowship programs. The event fostered fellowship among all members of the school and inspired them to strive for intellectual and personal excellence as they pursue success throughout their schooling and future career paths. We are happy to report this event was a success for a second year in a row, and we expect to continue this success in the upcoming years. Annual Lecture: "Big Data, Observational Studies, and Health Care” Written by Kerri Roach, Photo by Yung-en Fung Dr. Steven Pizer is a former research director for MA Fair Share, worked for MA Senate Human Service Committee, and was Executive Director for MA Citizen Action. He has more recently worked as the Director of Healthcare Financing and Economics Department of Veterans Affairs, completing evaluations, policy research, and health services research. Dr. Pizer recently joined Northeastern University’s Department of Pharmacy Practice in the School of Pharmacy and brings to us his leadership in the field of health care economics. During the Annual Lecture on April 1, Dr. Pizer discussed some important background aspects of health care economics and enlightened the audience on some of his recent projects. Some examples of the research he has been conducting are comparative effectiveness of diabetes medications, carotid endarterectomy vs. medications, prostate cancer treatments, and dabigatran vs. warfarin. He explained that the reason cost effec- tiveness research is so important is because it is the key to controlling cost and increasing the quality of healthcare in our country, which is currently struggling to control healthcare spending. Because of large multistate, multi-payer claims databases and regional health information exchange, the data available for cost effectiveness research are being transformed. Dr. Pizer gave an overview on selection bias and reporting associations without claiming causation and the use of instrumental variables to reduce the biased introduced to the studies. This lecture was very informative and provided a brief overview of important considerations for cost effectiveness research. In addition, the Annual Lecture served as a reminder of what to consider when conducting and the importance of such research. The Beta Tau chapter was honored to have Dr. Pizer present his expert views on cost effectiveness and pharmacoeconomic research at our Annual Lecture. Faces of Pharmacy Written by Alessandra Lyman On Tuesday, March 12, pharmacists throughout Massachusetts, as well as a number of pharmacy students from the three accredited pharmacy programs in MA, gathered at the Massacusetts State House to advocate for the profession and help promote the passage of three bills. These bills include giving pharmacists the status of health care providers, allowing pharmacy student interns to immunize while on rotations in their last year of the professional curriculum, and standardizing pharmacy audits. Northeastern University had an outstanding presence at the event, with a sea of white coats filling Gardner Auditorium. Current Rho Chi National President and Northeastern University School of Pharmacy Dean Jack Reynolds, as well as other NU faculty, were also in attendance to show their support. The university had representatives Dr. Jenny Van Amburgh and Matthew Schmidt, current Rho Chi member and Phi Lambda Sigma President, speak at the event to help students and pharmacists realize the value of what they were doing and how it could impact the profession of pharmacy in Massachusetts. After opening remarks from MPhA representative Dave Johnson and Senator Harriett Chandler, pharmacists and students broke off into groups to visit with legislators and their aides and advocate for the bills. Students found the experience rewarding as they were able to work side by side with current pharmacists and pharmacy faculty and were happy to put forward their commitment to the profession by advocating for quality patient care outcomes that pharmacists can provide. It was great to see such a large Northeastern University School of Pharmacy turn-out and we expect to participate in more of these advocacy days in years to come. CVS Quits Tobacco to Focus on Providing Health Care Written by Uswa Ahmad In an attempt to help their patients kick the cigarette habit, CVS Caremark, the largest pharmacy in the United States based on total prescription sales, announced in February that it plans on stopping the sale of cigarettes and other tobacco products by October. CVS is the first national pharmacy chain to take this step forward to promote the well-being of its patients. The announcement is a sign of the company’s attempt to transition from being a retail business to a health care provider. In an official press release, CVS Caremark President and CEO, Larry J. Merlo, said "Ending the sale of cigarettes and tobacco products at CVS/pharmacy is the right thing for us to do for our customers and our company to help people on their path to better health. Put simply, the sale of tobacco products is inconsistent with our purpose." Although the company estimates that it will lose about $2 billion in annual revenue, CVS Caremark is betting that it can gain more business by showing an interest in patient care. CVS recognizes that prescription sales for baby boomers have much more growth potential than cigarette sales, so it has placed a greater emphasis on forming ties with patient lifestyles. That is why, in addition to banning the sale of tobacco products, CVS has also announced that it will launch a nationwide smoking cessation program to provide patients with access to information and treatment options. This new initiative will help expand the role of pharmacists in providing patient care and may help CVS recover some of its lost revenue. CVS Caremark’s decision received praise from various public health advocates and even from President Obama. “As one of the largest retailers and pharmacies in America, CVS Caremark sets a powerful example, and today’s decision will help advance my Administration’s efforts to reduce tobaccorelated deaths, cancer, and heart disease, as well as bring down health care costs – ultimately saving lives and protecting untold numbers of families from pain and heartbreak for years to come,” said Obama in a prepared statement. Currently, it is unclear whether other major retail pharmacy chains will follow CVS’s lead, but they are now under pressure from government officials to address the paradox that exists between the distribution of medications to promote health and the sale of deadly tobacco products. Northeastern University became a smoke-free campus in 2013, so it appears this social movement away from tobacco will only gain momentum. Hypertension Guidelines: What’s New? Written by Angela Fu The Eighth Joint National Committee (JNC 8) guidelines for the treatment of hypertension were published in December 2013 in the Journal of the American Medical Association and have some significant differences from the JNC 7 guidelines, published in 2003. JNC 7 was based on a nonsystematic literature review that included observational studies and expert opinion, whereas JNC 8 considered mainly randomized controlled trials (RCTs). Rather than defining the cut-offs for prehypertension and stages of hypertension, the new guidelines consider only hypertensive patients and provide thresholds for drug treatment. Previously, separate goals existed for “uncomplicated” hypertension and subpopulations with comorbid conditions, but now treatment goals are similar for all hypertensive patients. JNC 7 recommended thiazide type diuretics as first-line therapy and listed five alternative classes, whereas JNC 8 specifies four first-line drug classes and suggests three treatment strategies. Notably, betablockers are no longer recommended first-line due to potential lack of protection against stroke. JNC 7 was broader in scope and addressed issues such as lifestyle modifications, blood pressure measurement methods, medication adherence, resistant hypertension, and hypertension in subpopulations. JNC 8 limits itself to answering three key questions regarding thresholds for pharmacologic treatment and selection of agents. are maintained at a blood pressure <140/90 because of adherence to the previous guidelines may remain on the same antihypertensive regimen as long as they are experiencing no adverse effects. JNC 7 recommended lower thresholds for patients with diabetes or chronic kidney disease, but JNC 8 found insufficient evidence to support the cut-off of 130/80. JNC 8 has also relaxed the treatment thresholds for those over age 60 from 140/90 to 150/90 because of some evidence that a lower systolic blood pressure goal provides no additional benefit. However, patients over 60 who JNC 7 Recommendations BP Classification SBP/DBP Normal <120/80 Prehypertension 120-139/80-89 Stage 1 Hypertension 140-159/90-99 Stage 2 Hypertension ≥160/100 Initial Treatment w/out Compelling Indication No drug indicated Thiazide type diuretic 1st line for most; may consider ACEI, ARB, BB, CCB, or combination Two-drug combination for most (usually thiazide type diuretic plus ACEI, ARB, BB, or CCB) JNC 8 Recommendations Age 60 years and older <150/90 mmHg (Grade A) Age 30-59 years Age <30 years DBP <90 mmHg (Grade A), SBP <140 mmHg (Grade E) <140/90 mmHg (Grade E) Diabetes <140/90 mmHg (Grade E) CKD <140/90 mmHg (Grade E) Other subgroups Not specified First line meds, nonblack, with or without diabetes First line meds, black, with or without diabetes ACE inhibitor, ARB, CCB, thiazide type diuretic (Grade B) CCB, thiazide type diuretic (Grade B for general population, Grade C for diabetes) ACE inhibitor or ARB (Grade B) First line meds, CKD Initial Treatment with Compelling Indication Drug(s) for compelling indications (heart failure, postmyocardial infarction, high CVD risk, diabetes, CKD, recurrent stroke prevention); CKD/ diabetes goal <130/80 Drug(s) for compelling indications, other drugs (diuretics, ACEI, ARB, BB, CCB) as needed, CKD/diabetes goal <130/80 Abbreviations: CKD – chronic kidney disease, CVD – cardiovascular disease, DBP – diastolic blood pressure, SBP – systolic blood pressure, ACEi – angiotensin-converting enzyme inhibitor, ARB – angiotensin receptor blocker, CCB – calcium channel blocker, BB – beta-blocker, Grade A – strong recommendation, Grade E – expert opinion in light of conflicting or insufficient evidence U P C O M IN G E V E N T : I N DU C T IO N C E R E M O NY J U N E 1 3 A T 7 PM ROOM 378 IN 140TF V IS I T U S A T W W W . NO R TH E A S TE R N . E D U / RH OCH I/ Alumni Profile: Linda Wang Written by Linda Wang sible. During my 6 years, I worked in a variety of different pharmacy settings – operating room pharmacy, inpatient pharmacy, outpatient pharmacy, industry, and research. However, my co-op at Novartis in early phase clinical trials, rotation at Biogen Idec in regulatory affairs, and extensive research experience under Dr. Waszczak solidified my interest in pursuing a career in the pharmaceutical industry. I loved the dynamic corporate environment and collaboration between the various departments on projects. My pharmacy knowledge was highly valued and aided me in critically evaluating scientific data and medical literature. I could see myself in this role where I could apply my clinical knowledge in innovative ways to improve patient healthcare globally. pharmacy organizations specific to my therapeutic area and continue expanding the fellowship program. I strongly advise students to step outside of their comfort zone and take on leadership roles, whether in a classroom setting or in a student organization. You will grow tremendously as a leader and as an effective communicator. During my time at Northeastern, I was president of three student organizations, co-founder of a dance crew, treasurer of APhA-ASP, Sponsorship Chair for Relay for Life, and an eboard member for several other organizations. I participated in leadership retreats and the Lead360: Global Pathways for Leadership program. As a natural introvert, my broad leadership experience helped me become a better public speaker Pharmacy was an ideal career choice for I am currently a Global Medical Affairs and taught me what kind of leader I me due to its flexibility in job location and fellow at Bausch + Lomb through the Uni- wanted to be. I advise students to be willdiversity of opportunities postversity of Southern California fellowship ing to step into new opportunities (the graduation. Even today, I’m discovering program. This one year fellowship promore it scares you, the better!) because other fields where pharmacists are making gram provides intensive training to help each experience, whether good or bad, can their mark (e.g., medical education, health me transition from a clinical background to teach you a valuable lesson. As students, outcomes research, medical communicaone able to handle cross-functional tasks we have the advantage of being taught new tion agencies, publication agencies). involving the clinical, medical, and marskills by experienced pharmacists – you keting departments. I plan to pursue an never know when those skills may come My view towards life, both professionally MBA in the near future while continuing handy. and personally, is to be open-minded and to work in medical affairs. I also hope to have as many different experiences as pos- take on leadership roles in professional