congress abstract - EPSA
Transcription
congress abstract - EPSA
36th EPSA Annual Congress 22nd to 28th of April 2013 Catania, Italy CONGRESS BOOKLET www.epsacongress2013.com CONTENT PRESIDENTIAL WORDS 5 VICE-PRESIDENT OF EDUCATION’S WORDS 6 CHAIRPERSON’S WELCOME 7 MEET THE RC 8 LIFE-SAVING INFORMATION 9 CONGRESS VENUE 10 EDUCATIONAL PROGRAM 14 PARTY INFORMATION 15 SYMPOSIUM 16 WORKSHOPS 19 TRAININGS 27 SCIENCE DAY 32 SPEAKERS’ CVs 39 4 36th EPSA Annual Congress PRESIDENTIAL WORDS PRESIDENTIAL WORDS Dear participant, High quality events are something EPSA always tries to offer its members, and the anticipation for this one has been sky-high! The Annual Congress is one of the main events in our calendar, and whether you’ve known EPSA for a long time or just discovered us, we have many things to offer. The EPSA Team and the Reception Committee have prepared an excel¬lent educational programme, on the topic of Specialisation and Educational Opportunities for Pharmacists. Whether our current education corresponds to our needs or not is a subject that is highly debated, and this programme aims to help you understand how our education should be developed in order to properly prepare us for the future. It is tailored to meet your needs and interests, having layers of different complexity that you can freely choose from and thus giving you the opportunity to progressively deepen your knowledge on each sub-topic as you see fit. Read more about it in the pages to come! Finally, no EPSA event would be complete without a fantastic social programme. How great it is to relax and party with friends after a hard day of work and learning experiences? What about having Mount Etna as a background for it all? Well, the Reception Committee has been working hard to give you just that, and you’ll be able to enjoy it all with pharmacy students from lots of different European countries! Don’t be shy, immerse yourself in the EPSA Spirit and be ready for many surprises! Welcome to the 36th EPSA Annual Congress and to the wonderful city of Catania! Pedro Barroca EPSA President 2012-2013 Catania | 22.04. - 28.04.2013 5 VICE-PRESIDENT OF EDUCATION VICE-PRESIDENT OF EDUCATION’S WORDS Dear congress participants, Specialisation in pharmacy. What does it mean to you? What does the person next to you think? You might notice that your views are quite different, as the definition of what specialisation in pharmacy means is currently debated in Europe. Also, the specialisation opportunities across European countries differ a lot: in one country you have to choose a branch of specialisation during your basic studies, in another you can do it as something extra before graduation and in a third country you might only have the option of specialising by doing another master or an extra few years of specialisation studies after you’ve completed your basic studies and so on. In some countries courses regarding specialisation in increasingly popular areas, like clinical pharmacy, are automatically provided to all students, whereas in others educational programmes of that sector might have been ended due to financial troubles. Just to give a taster about the palette of the different ways and situations we are talking about. Not everyone thinks students should specialise. Why might that be? Should specialisation opportunities be the same in all European countries? Why or why not? Should that be tied in with developing the basic pharmacy curricula or competency frameworks? How would you like to see the curricula developed? What should EPSA do about the topic and would it be possible to reach a consensus about to kind of an issue? I challenge you to think about these questions before attending the congress, try to listen to the perspectives presented by our speakers and discuss with your fellow students. In addition to sessions related to the theme of the congress we have a myriad of other interesting sessions. Keep your mind open, go and explore! Remember that you can only get as much out of the congress as you are willing to, so by trying to be active, engage and discuss you will definitely gain more. With these words I would like to wish you an exciting, fruitful and fantastic congress! Tiia Metiäinen EPSA Vice-President of Education 2012-2013 6 36th EPSA Annual Congress CHAIRPERSON’S WELCOME CHAIRPERSON’S WELCOME Dear participants, dear prestigious and distinguished guests, I’m very proud to welcome you to the warm and shining city of Catania, that for the first time in Italy is really honored to host an event with the importance and the significance of the 36th European Pharmaceutical Student’s Association (EPSA) Annual Congress (AC).Since when we received the official assignment during the 35th EPSA AC in Istanbul our enthusiasm was at the stars (in seventh heaven)and all the Reception Committee(RC)has been working hardly to realize this fantastic project. We received more 1000 application forms for the AC, a new record in EPSA’S history. We are also happy to host participants representing 29 EPSA members from all Europe and like individual members people from countries that we hope will be EPSA members in the next future. The RC wish that this congress can be an unbelievable experience of growing, learning, socializing ,entertainment and cultural exchange that remains forever like a special and unbelievable remembrance in the memory everyone of us. This year the topic is “SPECIALISATION AND EDUCATIONAL OPPORTUNITIES FOR PHARMACISTS - Make the difference that matters!” It’s very actual because nowadays work’s world is always more frenetic and ruthless so our minds must be the most open possible in direction to an European and global competitiveness and the update must be permanent and meticulous. So i consider that everyone will have the possibility to increase the field of opportunities about future through several workshops and trainings provided by EPSA Team members. I wish you all an awesome stay in Sicily, that I consider the most beautiful island in the world, and in my Catania, the real and unique ionic pearl. I want conclude a quotation very important for me which I believe blindly: “Action may not always bring happiness, but there is no happiness without action.” The RC hopes that this Annual Congress will be unforgettable for you and remain forever in your life. Enjoy the 36th EPSA AC in Catania! Guido Gangarossa Chairperson of 36th Annual Congress Catania | 22.04. - 28.04.2013 7 HEADER HEADER YOUR RECEPTION COMMITTEE Guido Gerlando Gangarossa Chairperson Giulia Malaguarnera Vice – Chairperson Ugo Marletta Registration Committee Coordinator Martina Di Maola Registration Committee Luigi Di Stefano Secretary Giuliano Saverio Gangarossa Treasurer Giorgia Gaudioso Travel Department Coordinator Maria Longo Travel Department Michelangelo Di Mauro Marketing and Partnership Officer Sonia Colianni Logistic Department Coordinator Federica Barbagallo Social Events Coordinator Barbara Morana Social Events Department 8 36th EPSA Annual Congress LIFE-SAVING INFORMATION Respect the other participants, speakers and organisers and be on time! If you are late you might not be let into the session! Remember that the Educational Symposium (Tuesday and Wednesday morning) is compulsory for all participants. In order for you to be able to attend the party in the evening, you must attend at least 50% of the optional educational program of that day (in addition to the Educational Symposium). In order to receive a congress certificate at the end of the congress you must have at least 50% attendance to the whole program. To collect Life Long Learning points, use the form you receive upon registration and fill out your details online as instructed on the form during/ after the congress. If you have any allergies, medical conditions etc. make sure the Reception Committee is aware. The Reception Committee will be on call at the hotel. Exact timetables (time of departure, address of venue) regarding evening program and sightseeing will appear at the Lobby, be sure to check all new information. Catania | 22.04. - 28.04.2013 9 CONGRESS VENUE VENUE’S MAP 10 36th EPSA Annual Congress CONGRESS VENUE Congress Accommodation The participants of the Congress will be accommodated at the Original Cucaracha Hotel (Viale Kennedy, 47 - 95121 – Catania) and Le Dune Hotel (Viale Kennedy, 10b - 95121 – Catania). Registration and Information Desk Throughout the Congress the Registration and Information Desk will be located in the lobby of both Hotels (Orginal Cucaracha and Le Dune). Catania | 22.04. - 28.04.2013 11 CONGRESS VENUE Congress Venue The Symposia will be held at the “Ciminiere Congress Centre” (Viale Africa - Piazzale Asia 95129 – Catania). After the Symposium on tuesday, the workshops take place in “Benedettini”. This is also where the elections on saturday are happening. 12 36th EPSA Annual Congress CONGRESS VENUE The rest of the educational program (wednesday, friday) takes place in “La cittadella”. Only thursady morning will take place in Palazzo Platamone. In that place, it is not allowed to eat. Anyways, pay attention to the flipcharts and RC information since rooms might change. Catania | 22.04. - 28.04.2013 13 HEADER CONGRESS PROGRAMME The Congress Programme can be found in the inner cover of this booklet. It consists of the following: The Educational Programme This includes the Educational Symposium, workshops (WS) and lectures as well as trainings. Abstracts for educational sessions are included in this booklet. In addition, you will receive the detailed educational programme with short speaker introductions. The Educational Symposium takes place on Tuesday and Wednesday, General Assembly (GA) The General Assembly is EPSA’s highest deciding body, and consists of all our members. Each EPSA member organisation has elected Official Delegates (ODs), who are represented at the GA. However, all EPSA members are very much encouraged to attend the GA, hear about the newest advancements in EPSA and participate in the hot debates on the pharmaceutical students’ future. Meet me fair Various EPSA partners will be represented at the Meet me fair. This is a golden opportunity to hear more about the different players in the pharmaceutical field, ask questions and meet some interesting people. Sightseeing The Reception Committee has arranged a wonderful tour around Catania for all participants. People will leave in groups at different times, which will be announced closer. Please wear the congress T-Shirt! Stay tuned for more information! Sports activity Feeling tired but you would like to keep up the energy levels for the final part of the program? Sports activity session is offering a recharging of your batteries to ensure you have the best congress experience. Join us on the beach, where a lot of opportunities will await you! To learn more about the content of the different parts of the Educational Programme and in order to decide which of the fantastic options you wish to attend, please go to the section of the booklet dealing with that specific part. Each day there will be parallel sessions taking place. Read the abstracts of each session and once you have chosen which one you wish to take part in, remember to sign up. You don’t have to sign up in advance for GA or Meet me fair, as they fit a lot of people. Workshops, lectures and trainings have a limited capacity so to secure your place, you are advised to sign up in advance. A few places will be left open for those who cannot decide beforehand or sign up for the congress later. Information about evening programme and any other important issues will be visible in the lobby daily, don’t forget to check and keep your friends up to date! 14 36th EPSA Annual Congress PARTIES HEADER Opening ceremony It’s time to dress in your cocktail dress or smart casual clothing and join the Opening Ceremony of 36th EPSA Annual Congress. Kick-start of the event will be a perfect place to reconnect with your friends and meet some new ones. Italian Night Italian night is where we will get to know what Italy and Sicily are all about. Joining the journey into Catania’s nightlife, as Italian Night is promising us a good evening out! Tip: Make sure to wear smart casual clothing that will include something in the colours of the Italian flag. Theme party: Body Painting In collaboration with “Academy of beauty arts, Catania”, Artistic Director: Prof. Liliana Nigro Techical Director: Veronica Maugeri, The Painters: Graziana Allegra, Andrea Campo, Corinna Elmi, Piergiuseppe Privitera, Alessia Andronico, Claudia Bonomo. A special surprise of our congress organisers is a Body Paining night. Playing with paint will make this evening memorable with all paint being provided on the venue. Make sure to bring good atmosphere with you and get to know other congress participants from another perspective. International night International night is a traditional and irreplaceable part of every EPSA event. During this evening you will have the chance to introduce the culture of your country to fellow colleagues and taste a small piece of other European cultures. Stands for food, drinks and souvenirs will allow you to “explore Europe” and with the sounds of traditional music enjoy the cultural diversity. Make sure to wear traditional clothing or other marks of your country and dress in something that you can be relaxed in. Tip from more experienced attendees: Eat well before this evening and leave your valuable stuff at home. Theme party: Spring Carnival Carnivals of Italy are well known around the world! This evening’s Theme party will let you become part of one and join the world of masquerades. Be creative and give your personal touch to this magical event! Gala Night Getting that gala dress and your best suit that you’ve saved through the congress means that this will be our last night of the congress. Nothing short of tradition, we’ll make sure to give it a goodbye it deserves! Bring your camera, your memories of the congress and use this evening to spend the last moments together with your friends in this special atmosphere. Catania | 22.04. - 28.04.2013 15 HEADER EDUCATIONAL SYMPOSIUM TUESDAY 9:00-13:00 Symposium Day 1: Educational opportunities - how to meet the needs of the future? Opening speech: Does the pharmacy curriculum reflect the future needs of our profession? Giuseppe Ronsisvalle (University of Catania, EAFP) Educational opportunities, bridging the gap between the lecture hall and real life, Wolf See (EMTRAIN) Medicines research and development (R&D) is an increasingly complex and rapidly changing process that necessitates collaboration across disciplines and different stakeholders (e.g. industry, academia, patients organisations, public authorities (including regulators), etc.). The Innovative Medicines Initiative (IMI), the largest public-private partnership in biomedicine, between the EU and the European Pharmaceutical Industries and Associations, EFPIA, has addressed this through 35 scientific and 5 Education & Training (E&T) projects currently underway. It is evident that one of the critical success factors is to strengthen the skills and competencies of European scientists and professionals working in R&D in order meet the demands for new cross-disciplinary skills, adapt to increasing industry-academia collaborations and foster operational excellence. IMI’s postgraduate E&T projects have implemented specific training programmes in the area of safety sciences (SafeSciMET) and pharmacovigilance & pharmacoepidemiology (EU2P), as well as integrated medicines development (PharmaTrain) and a programme for patients and other lay audiences (EUPATI). In addition a set of quality standards for the new programmes was developed and implemented. The EMTRAIN project has devised a comprehensive European online training catalogue “on-course®” which will become a portal and resource centre for all stakeholders (course seekers, course providers, employers etc.). EMTRAIN also works on establishing a common framework for Continuing Professional Development (CPD) in biomedical sciences via the LifeTrain-Initiative, and is developing a cohort of industry aware PhD students. The programmes aim at addressing the needs for scientist at all stages of their careers. The courses are flexible, modular, and focused on practical application and supporting mobility. Competency frameworks, Andreia Bruno (FIP) A commitment to academic development and excellence does not necessarily dictate a need to follow any one particular national model for pharmacy education, but rather to ensure that education is mapped to the required competencies of pharmacists to provide the relevant pharmaceutical services in any given country context. A framework for practitioner development should aim to provide guidance for professional and personal development of pharmacy students and practitioners delivering general pharmacy services in any patient care setting. Such a framework would facilitate continuing professional development, help individuals define gaps in knowledge and skills, and identify training and development needs. A competency-based developmental framework should be based on a modern concept of competence. A competency is a quality or characteristic of a person related to effective and sustained performance. It comprises knowledge, skills, behaviours and values. A competency describes typical behaviours observed when effective performers apply them to tasks. A competency framework is a collection of competencies that are thought to be central to effective performance. It is a complex construct but provides a practical and realistic framework for individual practitioner development, and hence a useful and pragmatic concept for the development of patient-focussed pharmacy services. This presentation will show the evidence and devlooment for a Global Competency Framework (GbCF) to support career development. 16 36th EPSA Annual Congress EDUCATIONAL SYMPOSIUM HEADER What does the future look like and how to prepare? - examples of e-learning, the pharmaceutical scientist and techology, Clive Wilson (EUFEPS) When I went to university to read physiology, my main sources of information were textbooks and lecture notes and my skill set was widened by attendance at various practical classes. Then, as a teacher I encountered WYSIWYG systems, simulators and was a very early adopter of PowerPoint and Excel. These assisted my communication - and also allowed me to explore the behaviour of systems; in essence I was teaching myself through interactions in silico. Now, we have many more intelligent media systems, open source software and information and gadgets. If you stand still, in intellectual terms, our knowledge base would quickly decay as the developments outside your field impact on the profession of pharmacy, the support team and the patient. Tomorrow is going to be different…very different! What are the tools that will impact my teaching and my research in 2015? Certainly ebooks because they are media rich and can directly test learning and application of knowledge. In drug delivery, extrusion and microfabrication will allow drug delivery systems and applicators to be constructed in small workshops or the home. The reusable plastic gizmo, constructed in recyclable PLA, will change how we approach engineering tasks. The common link is open-source knowledge - used to share information, inform ourselves, build robots and entertain us. WEDNESDAY 9.00-13.00 Symposium Day 2: Specialisation – why or why not? Defining specialisation, current situation in Europe (pre and post graduation), Lilian Azzopardi (EAFP) With the evolvement of pharmacy processes, the pharmacy profession and educators are faced with the issue of specialization. This concept opens up an array of considerations: which areas of specialization, how to prepare programmes of specialization, should specialization be considered at the undergraduate or post-graduate level. The implications surely point towards the need to strengthen the competencies in basic sciences and in basic clinical aspects so as to empower pharmacy graduates with the skills to pursue educational development. Currently the approach to specialization in Europe varies according to the area of pharmacy (hospital pharmacy, community pharmacy, industrial pharmacy) and depending on national requirements. Through the PHARMINE project, an EU-funded project led by the European Association of Faculties of Pharmacy, information on perception of specialization in pharmacy was identified. Though national flexibility in implementing and adopting specialization requirements for different areas may be the way forward at this stage, harmonization in the programmes towards specialization could be proposed. Catania | 22.04. - 28.04.2013 17 HEADER EDUCATIONAL SYMPOSIUM Specialisation in Hospital pharmacy, Roberto Frontini (EAHP) The presentation of Dr Roberto Frontini at the Wednesday symposium will look at the emergence of hospital pharmacy as a defined specialization across Europe over the last 40 years, its core components, and why the development of the specialization has been, and remains, such a central focus of EAHP activity. Dr Frontini will describe recent activity by EAHP to promote the need for legal mechanisms that can facilitate future cross-border recognition of hospital pharmacy specialization qualifications, and the intent and motivation behind these efforts. Referenced initiatives will include the 2011 Pharmine project which explored the extent of common pharmacy competencies across Europe, the 2008 FIP Basel Statements on global hospital pharmacy competencies, and the 2010-13 European Commission led project to modernize existing legal frameworks for recognition of pharmacy qualifications across European borders. Industrial pharmacy and research, Filippo Drago (University of Catania) This lecture will focus on new trends in drug discovery processes aimed to increase the chances of delivering truly novel compounds into the clinic. The global market for effective new drugs is growing. This is due to the new emerging countries, but also in the G7 countries there is a large expectation about new treatments, especially for chronic diseases. The big pharmaceutical companies are investing more and more resources to discover and develop new drugs. In spite of these enormous efforts, the final results of the pharmaceutical Research and Development (including new medical entities and biologics) are reducing. The mega blockbusters model for the development of a winning pipeline in the pharmaceutical companies is in a real crisis. Moreover the patent’s expiries for several important compounds put a strong pressure on the drug discovery departments in all Big Pharmaceutical Companies. The development of new drugs has the potential to provide patients with significant improvements in quality of life, and to reduce the future economic burden on health-care systems. Because the approval of drugs with novel mechanisms of action has been rare in recent years, there is the need to ameliorate the R&D process in this field. Focusing on treatments that target disease pathophysiology will improve the chances of developing therapies that go beyond current symptomatic therapies. Indeed, the identification of new molecular targets involved in the pathogenesis of CNS disorders represents the essential step for the design of new and efficacious drugs able to modify the clinical course of these disorders. Specialisation in community pharmacy, Jurate Svarcaite (PGEU) Specialisation has characterised scientific progress in medicine for nearly two centuries. Emergence of clinical pharmacy specialization some decades ago has extended this trend to the field of pharmacy. Since then many different specialisation programmes in pharmacy have been created, including specialty opportunities for community pharmacists. Up to now, there is no harmonized pharmacist specialty system at the European level. Many questions such as: What drives specialisation in pharmacy? When to specialize? Who should specialize? What is a pharmacy specialist? Etc. remain to be answered. 18 36th EPSA Annual Congress WORKSHOPS AND LECTURES HEADER TUESDAY 14:00-16:00 (Parallel Sessions) STELLA Modelling Clive Wilson, EUFEPS Pharmacokinetic modelling is widely used in the prediction of formulation performance. The ability to conduct ‘what if’ evaluations allows the design space to be explored and to discover those factors which are more or less important in the simulation. Most pharmaceutical processes can be represented by flows, whether they be physical engineering operations or biochemical processes. By scaling the relative rates of components in the pathways, we gain knowledge about how sensitive parameters are to small changes in one part of the model. In addition, the very act of constructing a model makes us have to estimate the parameters. This helps us define the missing key information that we need to acquire. STELLA is a commercial tool that is easy to use, runs on Windows and MacIntosh. It is very accessible –This short demonstration will introduce the audience to the modeller and attempt to show some of the key features. If you want to bring along a laptop with the software pre-loaded: you access it at: www.iseesystems.com/community/.../STELLA/STELLADemo.aspx EMTRAIN Wolf See and Tony Payton (EMTRAIN) The workshop will consist of a detailed introduction to and demonstration of EMTRAIN’s portal and course catalogue “on-course®” with the opportunity for participants to conduct searches for courses tailored to their requirements. Participants at this workshop are encouraged to register beforehand on the on-course® portal (www.on-course.eu) which will allow the full functionality of on-course® to be explored. It will also address the specifics of the EMTRAIN LifeTrain initiative with special attention to the individuals needs in continuing professional development and the possibilities to proactively plan for a career in pharmaceutical industry. EPSA EduProf Advocacy Platform Tiia Metiäinen (EPSA) The EduProf Advocacy Platform Workshop focuses on discussing the newly established European level pharmacy student advocacy platform and concrete actions to be taken next. Short term goals for the platform include generating advocacy guidelines and three general EPSA statements regarding topics voted by the platform representatives. These goals will be broken down into more tangible steps, also some important topics regarding the platform will be addressed. The workshop will be mostly based on the OST (open space technology) format and official Platform representatives will be prioritised in attendance. Catania | 22.04. - 28.04.2013 19 HEADER WORKSHOPS AND LECTURES Career planning and coaching Francesco Scimó The workshop is an excerpt from the program A Life Of Abundance. It will focus on goal setting, emotions and the way people build un-consciously their own future. TUESDAY 16:15-18:15 (Parallel Sessions) Deeper insights to competency frameworks Andreia Bruno (FIP) The role of the pharmacist is to ensure that medicines are accessible, safe, and used rationally by patients and providers. To create practitioners worldwide with the skills to perform these roles requires coordinated educational effort. Since 2008 the FIP Education Initiatives Development Team (FIPEd), the World Health Organisation (WHO), and the International Pharmaceutical Federation (FIP) have undertaken a collaborative programme to develop evidence-based guidance and frameworks through which to facilitate the sustainable development of higher education for the pharmacy workforce. The Global Competency Framework (GbCF v1) is a project from the FIPEd Development Team, which is intended to act as a mapping tool for foundation years of practice. “FIPEd-IPSF Student Learning Experience Questionnaire” is another ongoing project, which had a principal focus on the perceptions and experiences of students about their degree. The workshop will aim to provide the participants an insight on the projects and an interactive session on how students can be activity involve with their future practice and continuing education. Learning Objectives: to understand how to measure and use competency-based approaches for CPD and practitioner development, with reference to different levels of practice (UG, early years, and re-validation or expert practice). Students will be invited to try methods for validating a developmental framework based on professional competencies. Prudent use of antibiotics: European Antibiotic Awareness Day and the role of young pharmacists Dominique L. Monnet and Giovanni Mancarella (ECDC) This workshop will focus on the issue of antimicrobial resistance and prudent use of antibiotics. Antimicrobial resistance, or the ability of microorganisms to withstand treatment with medicines to which they were once susceptible, is a multifaceted public health problem. Prudent use means only using antibiotics when they are needed, with the correct dose, dosage intervals and duration of the course. Prudent use of antibiotics is critically important because antibiotic over-use unnecessarily causes bacteria to become resistant to antibiotic treatments. 20 36th EPSA Annual Congress WORKSHOPS AND LECTURES HEADER European Antibiotic Awareness Day (EAAD) is a European public health initiative coordinated by the European Centre for Disease Prevention and Control (ECDC). It aims to provide a platform and support for national campaigns about prudent antibiotic use. Across Europe each year the European Antibiotic Awareness Day is marked by national events and campaigns on prudent antibiotic use during the week of 18 November. The workshop will provide the opportunity to discuss young pharmacists’ awareness of the problem and their involvement in the initiative. Deeper insights to hospital pharmacy Roberto Frontini, Richard Price and David Preece (EAHP) The purpose of the EPSA Congress hospital pharmacy workshop is to heighten participant appreciation of the specialised roles of the hospital pharmacist, as distinct from other branches of the profession, and where identified trends in professional development may take the profession in future years. The workshop will examine and discuss the dominant emerging themes of hospital pharmacy in Europe, and the drivers of specialisation. In particular it will look at -The development of the hospital pharmacist role, and specialisation, over time -The hospital pharmacist’s unique relationship with particular areas of practice and complex patient groups (e.g. rare diseases, oncology, paediatrics, intensive care, emergency treatment and geriatrics) -The hospital pharmacist at the cutting edge of treatment and advanced therapies, and operation as a medicines research lead -The hospital pharmacist’s special patient safety role and role within the healthcare team -Potential areas of future professional role development The workshop will also provide a general introduction to the European Association of Hospital Pharmacists, its principal activities and opportunities for students to take part in its Congresses and its exchange programme. WEDNESDAY14:00-16:00 (Parallel sessions) Developing pharmacy education Giuseppe Ronsisvalle and Lilian Azzopardi (EAFP) During the workshop participants will be focusing on: 1.Where is the pharmacy profession moving? 2.What aspects need to be considered in pharmacy programmes to prepare graduates for the changes in the profession? 3.How to prepare students for lifelong learning? 4.Which areas of specialization should be considered? 5.Proposing a framework for harmonization of specialization programmes? Catania | 22.04. - 28.04.2013 21 HEADER WORKSHOP AND LECTURES Specialisation in regulatory affairs Lynda Wight (TOPRA) and Joao Duarte (EPSA) In the past, almost all regulatory professionals were pharmacists by training and the focus of the role was on pharmaceutical development and quality. Now, the role of the regulatory professional has developed hugely to become an important strategic component in the global development of medicines and devices, requiring wide ranging scientific and personal competencies. What does a new entrant to the profession need to know and how can their pharmacy training be used to best effect get that important first foot-hold on the regulatory career ladder? Why consider a career in regulatory at all: what does it offer and what are the options? This workshop will review the many responsibilities that a regulatory professional has and will aim to demonstrate that this is a role that is fulfilling for the brightest and best young scientists! Pharmacy awareness public health campaign Jurate Svarcaite (PGEU) and Monica Luca (EPSA) The community pharmacy practice contributes to the efficiency and effectiveness of European health systems, public health and positive treatment outcomes of individual patients. Nonetheless, awareness of the knowledge and capabilities of the pharmacist as a health professional are not properly known by the general public. It is frequently believed that the pharmacist is the one selling medicines and the seeming ignorance of the pharmacist’s extensive knowledge in pharmaceutical sciences stems from the fact that not much was seen and heard by the public. In times of change, the workshop would like to design a public health campaign that would tackle these wrong beliefs and better inform people about the professional training that pharmacists posses. A joint EPSA – PGEU project aims at making people realise pharmacists’ value as healthcare professionals. How well know do you think your future profession is? How is the community pharmacist perceived in your country? If you would like to be part of the change, then assess the level of awareness the general public has on the professional abilities of the pharmacist and how patients relate to community pharmacy in this workshop. 22 36th EPSA Annual Congress WORKSHOP AND LECTURES HEADER WEDNESDAY 16:15-18:15 (Parallel sessions) Student Advocacy Heidi Jäntti (The Finnish Pharmacsists’ Association) Advocacy and lobbying are work that happens in the background most of the time and is hard to recognize. In this workshop participants get the knowledge of the procedure in different levels of advocacy and how to create positive change themselves. EU Institutions and decision making – what should a pharmacy student know? Guilherme M. Ferreira and Jurate Svarcaite (PGEU) The European Union isn’t a government, a solely union of countries, or an international organisation. Rather, the 27 Member States have relinquished part of their sovereignty to EU institutions, with more and more decisions made at the European level. Legal competences of EU institutions have increased since its establishment 60 years ago and are likely to grow with the establishment of monetary union. Increasingly, the decisions made at the central (Brussels) level directly impact our daily lives and jobs locally. In this workshop we’ll try to explain you the creation and development of the European Union we live in today and its current structure and legislative processes. We will explain structure of the main EU Institutions and Agencies with the particular focus on those relevant to our profession. From a stakeholder perspective, we’ll try to explain the main ways of interaction and engagement with the European Institutions and the importance of these actions both for the PGEU and EPSA. Domestic violence – what can a pharmacist do to spot and help a victim? Belkis Unver and Göknil Pelin Coşkun (Marmara University) All offensive conduct may be characterized as violence. Victims of domestic violence are, in general, women and children. Domestic violence against women may be defined as violence exhibited to women at their own homes where they should be safe and secure by people from whom they expect love and respect. Every fifteen minutes, one woman is beaten by her spouse or partner in the United States. In this workshop, reasons for domestic violence, measures to overcome this violence and the role of pharmacists should adopt in fighting against domestic violence are going to be evaluated. Catania | 22.04. - 28.04.2013 23 HEADER WORKSHOPS AND LECTURES THURSDAY 8:30-10:30 (Parallel sessions) GSK Workshop Sanziana Marcu and Patricia Pessoa (GSK) The Better Oral Health European Platform is a project launched in 2011 to promote better access to dental healthcare and increase awareness of preventative measures across Europe. We believe that Pharmacists, as first line healthcare providers, can have an important role in this cause. There are no doubts that Pharmacy students – the Pharmacists of the future – are a key element to raise awareness and educate the population on the effective use of the right oral care products. This will not only increase the quality of life of the individuals, but also will have a positive impact by reducing the cost of oral diseases in Europe. The two workshops that are going to be held during the 36th EPSA Annual Congress are intended to be a holistic approach to the BOHP, leveraging Pharmacy students’ knowledge around Oral Health to the next level. For more information, access the platform’s website: http://www.oralhealthplatform.eu/ THURSDAY 11:00-13:00 (Parallel sessions) Young Professionals Katrine S. Hansen (EPSA) Have you decided in which area you would like to work in after graduation? And do you want more insight in the different pharmaceutical areas? The aim of this workshop is to give the participants an opportunity to meet professionals from different fields. Many students don’t know the wide range of working opportunities they have after graduation. The session will consist of an introduction to the different areas and afterwards the participants will in small groups have an opportunity to ask questions from the young professionals, whose field they find most interesting. FRIDAY 8:30-10:30 (Parallel sessions) IPSF collaboration session, insights to WHO Miloš Stojković (EPSA) and Radek Mitura (IPSF) The International Pharmaceutical Students’ Federation (IPSF) was founded in 1949 and is a global federation of pharmacy and pharmaceutical students and recent graduates. Being EPSA’s sister organisation, IPSF and EPSA are traditionally holding a joint session at congresses of each association. This session will aim to provide you with a deeper 24 36th EPSA Annual Congress WORKSHOPS AND LECTURES understanding of the IPSF structure and aims, particularly introducing World Heath Association and presence of pharmacy students at the World Health Assembly. In addition, participants of this workshop will be able to understand and give valuable inputs to the statements that are presented to the World Health Assembly by IPSF. FRIDAY 11:00-13:00 (Parallel sessions) Reimbursement systems Kagan Atikeler (Ankara University), Avgoustinos Kotsonis (GSK) and Nilhan Uzman The global pharmaceutical market is growing every year. That brings new expenses to patients/Reference Pricing has been used for some therapeutic groups in the past few years. Therapeutic Reference Pricing has been used for some therapeutic groups in the past few years. In this workshop we will focus on previous and new reimbursement methods which have been available in the past few years. We will focus on a new pricing system called ‘’Jumbo Group Pricing’’, focusing on three different therapeutic groups which have the same effectiveness and safety profile within the therapeutic group. So each medicine in same therapeutic group may be used instead of another. We will show how Jumbo Pricing System may affect the budget of payers with some example countries. The workshop includes a role play exercise where we will learn the whole process of new and old systems interactively. We will see how much expenses can be reduced or increased with the new system. GSK Workshop, Sanziana Marcu and Patricia Pessoa (GSK) See Thu 8:30-10:30. Speed Networking + kickstart your career! Speed Networking will allow you to interact with some EPSA Alumni, which already started their professional careers. Grab a moment to ask them about your own expectations and their advice in the area you’re mostly interested in following after your studies. A short session on how you can kickstart your career will also take place right after, where you can discuss some of your expectations and get some ideas on how to brace yourself for the working life ahead. The speed networking session offers a nice chance to practice your networking skills right away, if you have chosen to participate in the networking training in themorning. Catania | 22.04. - 28.04.2013 25 WORKSHOPS AND LECTURES FRIDAY 14:00-16:00 (Parallel sessions) Fundraising and partnership opportunities for student activities Gabriela Valentová, Robert Zika, Diogo Viana and Domen Kutoša (EPSA) Have you ever wondered why there are people that are just having big dreams while others go and live them? Do you have new innovative ideas and projects you would like to put into practice but can’t find a way to do it? Your NGO desperately needs new sponsors but just doesn’t seem “sexy” enough for the real big fish? This fundraising work shop is right for you! We will show you how to fund your initiatives and train you how to sell your ideas to others. Learn about how to build and maintain relationships and slowly reinvent your donor base, at the same time. Determine how to communicate to get your organization’s message out to supporters. So, let´s fundraise! FRIDAY 16:15-18:15 (Parallel sessions) TWINNET Project, Gabriela Valentová (EPSA) Are you interested in intenational exchanges? Have you already participated in TWINNET project? Are you planning to organize one? Come and join us! You will learn about the project, little bit about grant opportunities for the exchanges and we will present all the exciting news that happened in past months around TWINNET! You can also take part in brainstorming about future of the project and if you have any new ideas, come and make them become reality! 26 36th EPSA Annual Congress TRAININGS EPSA Trainings are participant-focused interactive sessions facilitated by EPSA Trainers The trainer plans the framework for the session, which is then shaped by the inputs of the participants. Trainings usually focus on soft skills, i.e. personal competencies, that can be developed and strengthened, like communication skills or stress management skills. EPSA Trainings are a product of the EPSA Training Project, aimed at increasing awareness of soft skills and their importance, as they are not yet incorporated into university curricula in Faculties of Pharmacy to the extent that EPSA members feel they should, helping to meet the demands and cease the opportunities of modern working and personal life. Catania | 22.04. - 28.04.2013 27 TRAININGS TUESDAY 16:15-18:15 (Parallel sessions) Presentation Skills Lucas Besson (Trainer), Sandra Hočevar (EPSA Trainer) Science Day presenters and NGT participants prioritised. THURSDAY 08:30-10:30 (Parallel sessions) Learn to control behavior with NLP Inkatuuli Heikkinen (EPSA Trainer) & Monica Luca (EPSA Trainer) When is the last time you took a good look at yourself, your actions and your thought process? Wanting to make a change in your life but not sure where to start from or what might really help you achieve this? This training is designed to help you reconnect with yourself and give practical examples of how to better communicate with the rest of the world. From getting to know your behavior pattern to understanding how your mind can become your best ally, the session will provide you with detailed information about Neuro Linguistic Programming and its implications in day to day life. Best uses of NLP techniques will be investigated for several fields and the power of language will be evaluated. In case you have already attended training in communication or stress management, we believe this is your next step in development! Approached issues: •Neuro Linguistic Programming - the basics •Mirroring & Rapport - use your body language to build up a good atmosphere •Maps of the world - are you in control of your life? •Anchoring - practical tools to manage your reactions 28 36th EPSA Annual Congress TRAININGS THURSDAY 11:00-13:00 (Parallel sessions) Be or not to be? How to make the right decision? Sandra Hočevar (EPSA Training coordinator), Merete Tschokert (Trainer) We are sure that you have already experienced times, when you needed to accept tough decision. Was this stressful for you? Did you regret your decisions? In this training we will present few techniques of decision making. This will help in your future carrier, because with right step and right question to yourself or to your co-workers, you can make success. Be satisfied with your path in life! Make your department, your pharmacy glow! FRIDAY 08:30-10:30 (Parallel sessions) Networking- The art of hooking up with the Success Jorge Batista (Trainer), Avgoustinos (Austin) Kotsonis (Trainer) Ok so you wanna know more about Networking, hum!? What is it, how is it done, and if you are able to do it, right? Well if those questions are in your mind, you definitely became a suitable candidate for this training. This session is designed for motivated young students with an interest on obtaining new Neworking skills and tools, in order to succesfuly create and maintain professional and/or personal connections (EPSA AC participants). Participants will create a definition of Networking, while developing motivational speech and group discussions. The training will focus on the Do’s and Dont’s of the topic, as well as will talk about elevator speech exercises. Attendants will expect a lot of pratical exercises on How to network and how to do the follow-up of their new contacts. Approached issues: Focus on the importance of networking. Understand how Network works and explore techniques how can it be applied to to the real life. Get familiar with Networking Tools(Facebook, LinkdIn, etc). What we should do and don’t while networking. Network targeting. Optimise your optimism – How to make yourself happier Louise Winnecke Jensen, cand.pharm., EPSA Trainer and HLM Have you noticed how some people are almost always happy? Maybe you are even one of them! Regardless, you will probably leave this training as a happier and more optimistic person. We will focus on different life perspectives, and try to figure out what it is that makes people happy. We will look into different ways of motivating yourself, and come up with strategies on how YOU can become more self-aware, more optimistic, and more satisfied with your life. This might sound overly romantic, but in fact we are able to influence our own mood by cognitive efforts. Ithowever requires awareness and determination, and of course, the knowledge on how to do it. Whether you are the eternal optimist, more on the pessimistic side, or somewhere in between, you are likely to find this training funny, useful, and not least - very positive about life! Catania | 22.04. - 28.04.2013 29 TRAININGS FRIDAY 14:00-16:00 (Parallel sessions) Unleash your creativity Stefan Rack (EPSA Design Coordinator, EPSA Trainer), Mara Lefter (Trainer) How do ideas flourish and become reality? Do geniuses actually exist or is it all just creativity playing with intelligence? Where do breakthroughs come from? Find out how creativity can open paths that were so obvious that you missed them, how thinking in new ways can bring day-today innovation and how to make ideas bubble up. We are going to focus on: understanding the creative process; overcoming hesitation and self-doubt; learning how to open up; overcoming barriers that block the creative processes. Emotional Intelligence Jasna Puh (EPSA Trainer) and Ioana Bogdan (EPSA Trainer) Have you ever dreamt of a successful life? If your answer is positive, then you should participate in this training because together we will define the way to reach the success using the EQ of each of you. EQ is the abbreviation for “Emotional Intelligence˝, which is a way of recognizing, understanding and choosing how we think, feel, and act. It shapes our interactions with others and our understanding of ourselves. It defines how and what we learn and allows us to set priorities. EI actually determines the majority of our daily actions. One research suggests it is responsible for as much as 80% of the “success” in our lives. Are you curious to develop or discover the ability to process emotional information? Then you should definitely join us on this emotional ride p.s.: Never forget that affective components of intelligence may be essential for success in life. 30 36th EPSA Annual Congress TRAININGS FRIDAY 16:15-18:15 (Parallel sessions) Wanna improve leadership skills, come to eat our pills! David Ćechlovsky (Trainer), Jakub Weber (Trainer) Each of us has different experiences of leadership from people around us and even from the way we lead our own life. Sometimes it is upon us to lead others and as pharmacists we will need to “lead” patients to an adherence and successful treatment. Therefore the leadership skills could be considered as essentiality for our daily life. In small groups (like school or hobby classes) we need to modify the leadership according to different situations, which we have to face. It would be hard to achieve greater things without leaders, because they are the ones in the group, who motivate, who ensure reaching the aim, who develop good relations, solve conflicts between the members, etc. Learning objectives are to understand what leadership is, what is a successful leader, hoe to become a succesful leadet. how to raise the level of our self awareness, our leadership style and preferences. KEEP CALM AND DON’T PANIC…here’s your stress management training! Sandra Hočevar (EPSA Training coordinator), Marina Knezović (Trainer) Have you ever had a personal problem and couldn’t really focus on anything else? How many times have you studied for an exam and ended up not going? Did you ever felt like you could get a better grade than you did? We are living in a world where we come upon stressful situations every day. Not knowing how to deal with these situations can make us frustrated, unhappy and it has a huge impact on our body, mind, emotions and behavior. Stop making stress getting the best of you and use it to be the best! During this training we’ll approach the topic through theory, exercise and interactive discussions. This training is designed for all the students who want to learn more on how to manage stress, be more efficient, reach their goals and, in the end, to be happier. Catania | 22.04. - 28.04.2013 31 SCIENCE DAY 5th EPSA SCIENCE DAY EPSA Science Day gives the chance for students to present their research work to both peer students and professionals, and at the same time sharing their knowledge and practicing for the future. In a relaxed environment, but closely looking like a professional event, this activity sets the perfect start up for students who are eager to share their knowledge and their work. As Pharmacy is an area constantly developing and changing, it is important to keep up to date. Being scientific research always at the state of the art, this approach to Pharmaceutical Sciences creates an opportunity to understand some hot topics where R&D is done by our fellow students, all around Europe. From different areas, as long as they fit in the realm of Pharmaceutical Sciences, students are invited to present their work to whom who may be interested in learn and get to know more about it. If you are interested in joining us for a day of Science, Research and Learning, make sure you register for this event! Jorge Batista, EPSA Educational Affairs Coordinator Find the abstracts of the Science Day applicants on the next pages. 32 36th EPSA Annual Congress SCIENCE DAY 1. Name: Agata Kuchcicka, YPP (Poland) Title: Quantitative structure-retention relationship of antitumor acridinone derivatives Abstract: Acridines belong to a group of polycyclic heteroaromatic compounds and show a broad spectrum of biological activity. Using a unique method, which is chromatography, has provided comparable retention data for sets of structurally diversified analytes. Moreover, the lipophilicity values of selected 21 acridinone derivatives were measured by gradient ReversedPhase High Performance Liquid Chromatography (RP-HPLC) using a C8/C18 stationary phase with a water/acetonitrile mixture as a mobile phase. The retention times obtained served as input data and appropriate log kw and log k0 values were calculated using the DryLab programme. The subject of the presented work was to determine the relationships between HPLC retention parameters (retention times and log kw) of 21 acridinones differing in chemical structure and characterized by antitumor activity and their calculated parameters of lipophilicity. 2. Name: Ana Šarčević, AHUPS (Turkey) Title: Evaluation of pneumococcal community-acquired pneumonia antimicrobial treatment in a tertiary-care - Teaching Hospital Abstract: Misuse and overuse of antibiotics lead to antibiotic resistance which is a global public health problem today. Our aim was to evaluate the appropriateness of antimicrobial treatment of community-acquired pneumonia (CAP), according to the Slovenian guidelines for CAP. Retrospective cohort study was conducted reviewing medical records of patients, who have been hospitalized at the University Clinic Golnik in 2011 for CAP caused by Streptococcus pneumoniae. The final study sample included 58 patients, 74.1% older than 65 years. 46.6% were smokers. Antibiotics were administered within 4 hours after the diagnostic of CAP to 86.2% of patients, considering the right choice in 89.5% of the cases. Most frequent empiric choices of antibiotics were amoxicillin/clavulanic acid (53.4%) and moxifloxacin (22.7%). Susceptibility testing was performed in 94.8% of cases but consequently just 15.5% of therapies were changed, where 8.4% represented a step down to the antibiotic with a narrower spectrum of activity. Treatment was successful in 67.2% of patients. Quality indicators showed relatively good compliance (above 75%) with the guidelines, with the exception of PSI/PORT determination. Practice of not changing broad spectrum empiric treatment, needs to be changed in order to prevent or reduce occurrence of bacterial resistance. 3. Name: Bengisu Turgutalp, IUPSA (Turkey) Title: Development of antibacterial thermo-reversible Pluronic F-127 gel formulation containing lysozyme and lactoferrin Abstract: The purpose of this study was to assess the antibacterial potential of Pluronic F127 formulations of lysozyme-lactoferrin (2:1) against Streptococcus mutans, Neisseria mucosa, Gardnerella vaginalis and other pathogens. Lysozyme is present in the mucosal secretion such as saliva and tears. Lysozyme and lactoferrin possesses antibacterial effect. This formulation as a potential therapy for oral and vaginal administration, an appropriate hydrogel composition (20 wt % Pluronics F127) was applied to the mucosa. After the researches and antimicrobial tests were performed respectively following concentration; 12,5 – 400µg; 6,25 – 200µg; 0,125 – 4 mg. Finally that the minimum inhibitory concentration (MIC) of this product is respectively (400 µg – 200 µg – 4 mg) bactericidal effect for N. mucosa and bacteriostatic effect for G. vaginalis. Catania | 22.04. - 28.04.2013 33 SCIENCE DAY This formulation as a potential therapy for oral and vaginal administration, an appropriate hydrogel composition (20 wt % Pluronics F127) was applied to the mucosa. 4. Name: Burcu Kelleci, Damla Kavukoğlu, AHUPS (Turkey) Title: Current therapy and future perspectives for Alzheimer’s disease Abstract: Alzheimer’s disease (AD), a progressive neurodegenerative disorder and most prevalent cause of dementia with ageing. AD is characterized by deposition of beta amyloid (Aβ) as amyloid plaques and neurofibrillary tangles. Pharmacological treatment of AD is based on the use of five major groups of drugs. These include cholinergic treatment, antiglutamatergic treatment, vitamins and antioxidants, nonsteroidal anti-inflammatory drugs (NSAIDs), and pharmacological management of neuropsychiatric symptoms. Cholinesterase inhibitors (tacrine, donepezil, rivastigmine, and galantamine) are widely used in treatment of AD due to deficiency in cholinergic neurotransmission in disease. Another approach is to block glutamatergic neurotransmission by glutamate receptor N-methyl-D-aspartate (NMDA), which has a role in neurotransmission and plasticity. Memantine is a specific NMDA antagonist which is used for the treatment of moderate to severe AD. Oxidative stress and free radicals are reported in the pathophysiology of many diseases including AD. Future treatment strategies for AD mostly focus on anti-amyloid therapy based on two approaches. First approach is inhibiting , and secretase enzymes in order to reduce production of amyloid protein. Second approach is immunisation (A vaccination) to induce A clearance. There are also several reports showing benefits of metal chelators and cholesterol lowering drugs in treatment of AD. 5. Name: Cansu Sönmez, Dicle Demir, Zerren Araman, IUPSA (Turkey) Title: Edible Film Formulation for Oral Hygiene using Lactoferrin and Lysozyme Abstract: Conventional drug delivery systems may sometimes present problems controlling the drug release and the effective concentration at the target side. The need for delivering drugs to patients efficiently and reducing the side effects has thus been a key point in the development of new drug delivery systems. Oral mucosal delivery is currently the safest, most convenient and most economical method of drug delivery having the highest patient compliance. An edible film form that disintegrates rapidly in oral cavity with the help of saliva, resulting in solution or suspension without the need of water is known as a mouth dissolving film. The aim of the study is to formulate such an edible film for oral hygiene. The present study relates to film strips which comprise natural products and biotechnological product formulations that can be absorbed from oral mucosa. Apart from these, there are also pullulan structures in polysaccharide form that does not have a pharmacological effect. The film containing active ingredients (lysozyme) is prepared using solvent casting technique. Turkish wine extract*, freed from its alcohol content via evaporation then freezedried, is used as a taste masking agent. * Patent: A dissolvable film strip comprising natural components. Document Type and Number: WIPO Patent Application WO/2011/036599 Kind Code: A1 34 36th EPSA Annual Congress SCIENCE DAY 6. Name: Carmen Sultan, SSFB (Romania) Title: Quantification of polyphenolic compounds with antioxidant action from various plant species Abstract: Nowadays many diseases are influenced and some are generated by oxidative stress which results from free radicals and reactive oxygen species. This is why research is oriented towards finding a natural solution: vegetal antioxidants. Polyphenolic compounds (flavonoides, caffeic acid, chlorogenic acid) from plants are known to have antioxidant properties and they could be used in therapy. Crataegi fructus, Daucus carotae tuber, Aurantii pericarpium and Myrtilli fructus extract were subject to pharmacognostic analysis and HPLC analysis to determine the free radical scavenging and antioxidant properties. In Crataegi and Myrtilli fructus were identified polyphenolic derivatives (flavanoids, anthocyanins, proanthocyanidins, and catechol). In Daucus carota tuber were determined tetraterpenoids compounds such as carotenoids and in Aurantii pericarpium were found flavonoids, proanthocyanidins and catechol. HPLC analysis separated caffeic acid in Crataegi fructus and Aurantii pericarpium, ferulic acid in Aurantii pericarpium and Myrtilli fructus, quercetol in Daucus carota tuber and Crataegi fructus. The analysed plants proved to be an important source of compounds with antiradicalar activity thus justifying their use associated with treatment for different types of ailments (disorders caused by capillary fragility, angiopathy and diabetic retinopathy, hemeralopia, dermal diseases and cardiovascular disorders). 7. Name: Karolina Pogoda , Aleksandra Polak, YPP (Poland) Title: Determination of resveratrol in dietary supplements and assessment of their antioxidant activity Abstract: Resveratrol (3,5,4’-trihydroxy-trans-stilbene) is a polyphenolic compound found in the skin of red grapes, red wine and Japanese knotweed (Polygonum cuspidatum). Extremely interesting, multiple biochemical and molecular actions presented by resveratrol became the crucial reasons of the constantly increasing sales of nutritional supplements, which are available over-the-counter on the pharmaceutical market. The aim of this study was to optimize chromatographic method for the determination of resveratrol in food supplements and evaluation of their antioxidant activity. Dietary supplements used in the project, were available on the Polish Pharmaceutical market, one containing resveratrol only (e.g. Trans Resveratrol®) and the other multicomponent supplements (Cellasene®, LongaVit®, Natursteron®, Nutrof®). Determination of resveratrol was performed using isocratic reversed-phase high performance liquid chromatographic (RPHPLC) with spectrophotometric detection (λ=306 nm) and mobile phase: 0.2% HCOOH / water: acetonitrile (70:30). The antioxidant properties of tested supplements were set out in vitro by indicating the efficiency of inactivation the synthetic stable radicals (DPPH •). For each preparation was calculated IC50 value, which determines the concentration of the preparation causing 50% inhibition of radicals. In final stage of the experiment, all tested supplements were compared in terms of the amount of active substance they contained, and also their antioxidant potential. 8. Name: Laura Cabello-Murgui, FEEF (Spain) Title: Students’ Academic Congress: A tool to promote the transferable skills and new knowledge in pharmacy students Catania | 22.04. - 28.04.2013 35 SCIENCE DAY Abstract: The development of transferable skills has been emphasized by the EEES and is especially important for the future pharmacists. We tried to implement the preparation and performance of a students’ congress as a strategy to promote communication skills, research skills, team work and leadership. In this paper, we present the methodology used to celebrate the academic congress and exhibit participation data, evaluation data of the participants and organizers. This congress is organized by students and for the students, with the collaboration of the university. 9. Name: Liliya Bogdanova, BPhSA (Bulgaria) Title: The role of the Bulgarian hospital pharmacists in clinical trials Abstract: In hospital settings it is extremely important proper medication to be allocated to any patient in need at any time and under appropriate form. On the other hand, drug use monitoring during clinical trials is important to be done not only by physicians but also by a hospital pharmacist. The hospital pharmacist has the ability to be more closely acquainted with the mode of action and pharmacological properties of the test drug, the expected ADRs, interactions, etc. The clinical trial team includes Doctors, Nurses, Pharmacists (often called Research Pharmacists) as well as other healthcare professionals. The Research Pharmacist is an appropriate, qualified individual (i.e., licensed/registered, if appropriate) designated by the protocol to perform the day-to-day pharmacy activities and study product management including, but not limited to, the procurement, storage, preparation, dispensing, and final disposition of study products for. The aim of our research is to study the role and responsibilities of the hospital pharmacists in clinical trials in Bulgaria. We contacted a number of hospital pharmacies, whose managers were interviewed. Analysis of the results shows that current practice in Bulgaria allowed hospital pharmacists to be involved in clinical trials but these are not prevalent. 10. Name: Saric Marija, Sandra Vladimirov, NAPSER (Serbia) Title: Oxidative stress and antioxidative protection parameters in children suffering from acute pyelonephritis as indicators of kidney function and inflammation persistence Abstract: Acute pyelonephritis is an inflammatory renal tubulointerstitial disease. The inflammation is characterized by increased oxidative stress and can progress into a chronic form and lead to kidney failure. The aim of this study was to determine the correlation between oxidative-stress status parameters and acute infection persistence and renal failure risk in children with this disease. The study included 50 children, averagely 14 months old, on admission and during hospital discharge. Total oxidant status (TOS), total antioxidant status (TAS) and prooxidant-antioxidant balance (PAB), CRP, and urea and creatinine were analyzed in patient’s serum. Patients were divided regarding their CRP levels and the degree of renal impairment. It was determined that increasing TAS values increase the likelihood of a longer infection and that TAS has a moderate accuracy potential for separating patients with different probability of longer infection. It was shown that decreasing PAB values significantly increase the likelihood of developing renal failure and that PAB has a good discriminatory ability for separating children with high from those with low renal impairment probability. 36 36th EPSA Annual Congress SCIENCE DAY Results of this study indicate that these parameters could one day be used for differential diagnosis and prognosis of acute pyelonephritis. 11. Name: Natalija Peric, BPSA (Serbia) Title: Synthesis, chemical and biological characterization of 21-ester of fluocinolone acetonide with 2-isoxypropanoic acid Abstract: The aim of this study was synthesis, chemical and biological characterisation of 21-(2’-isoxypropanoil) ester of fluocinolone acetonide (FA-21-IPP). FA-21-IPP was synthesized by using flucinolone acetonide and earlier synthesized 2-isopropoxypropanoic acid, with THF as solvent, and HBTU as acid’s activator. PAMPA test revealed that synthesized C21 ester of flucinolone belongs to a class III permeants with high retention in the membrane (99%) and low permeability through the membrane (<1%). The newly synthesized C21 flucinolone acetonide ester has shown significantly stronger activity compared to standard corticosteroids due to test of Croton oil. After 24h mass edema has reduced for 70%. The newly synthesized FA-21-IPP is prodrug which should be activated to active form by esterases on the application site. Due to PAMPA test and test of Croton oil, FA-21-IPP shows significantly higher permeation and biological activity than conventional corticosteroids. This implies that FA-21-IPP can be applied in much lower doses than conventional corticosteroids, which consequently causes less systemic side effects. 12. Name: Rebwar Saleh, NoPSA (Norway) Title: Study of Nano Particulate Polymer Coated Liposomes Abstract: Reduced or absence of saliva secretion can result in issues related to dental health like caries, wearing and tearing of teeth. The reasons for dry mucus can be diseases, side effects of drugs or radiotherapy, and aging. A system, in particular nanoparticle system, that could bind to and hydrate mucus would reduce the discomfort for patients, and prevent the additional issues related to dry mucus. Liposomes have been investigated as drug delivery systems both for oral, parenteral, and local treatment. One major issue with oral cavity in treatment is low residence time because of “washing-off” and involuntary removal of a dosage form. Using a mucoadhesive polymer would increase the residence time of the system. Chitosan and Pectin have both been shown by other researchers to be mucoadhesive. The aim of this study was to determine liposomal formulations ability to interact with mucin in solution, measuring change of size, turbidity, and zeta potentials. Positively charged liposomes and chitosan coated liposomes were shown to interact more with mucin compared to negatively charged liposomes and pectin coated liposomes. Mucoadhesive drug delivery systems have the potential for increasing residence time. Combining this type of analyses with other investigation such as ability to hydrate mucus would lead to determination of most optimal choice of delivery system for treatment of the oral cavity, including dry oral mucosa. 13. Name: Srđan Radak, NAPSer (Serbia) Title: Determination of nitrogen and organophosphorous pesticide residues in foods of plant origin – method validation Abstract: Combination of QuEChERS method and gas or liquid chromatography with mass spectrometry has enabled pesticide residue analysis in wide analytical range with high selectivity and sensitivity. These analytical tools have become a mainstay in most laboratories for pesticide monitoring that meet global standards. Validation of QuEChERS/GC-MS method for analysis of selected nitrogen and organo- Catania | 22.04. - 28.04.2013 37 SCIENCE DAY phosphorous pesticide residues and evaluation of measurement uncertainty. Validation study was conducted on organically grown potatoes and carrots, fortified with standard mixture of nitrogen and organophosphorous pesticides, at two concentration levels, prepared by QuEChERS method and analysed by GC-MS. Limit of quantification of analytical method of 10 μg/kg reached 63% of target compounds in both examined matrices, and additional 21% compound in just one. Estimated limit of quantification of instrumental method was below or at the level of 10 μg/kg for 89% of analytes in both matrices. Matrix-matched calibration curves were constructed in the range defined by limit of quantification at lower level and 500 μg/kg as the upper level. At 10 μg/ kg fortification level, 63% and 76% of analytes showed acceptable recovery values in potatoes and carrots matrix, respectively. At 100 μg/kg fortification level, those values were 76% and 74%. Pesticides with good recovery values were also characterized by good precision. Evaluation of expanded measurement uncertainty showed that this parameter was below 50% for all pesticides meeting the validation criteria. Validation study and evaluation of measurement uncertainty confirmed the quality of multiresidual QuEChERS/GC-MS method for the analysis of selected nitrogen and organophosphorous pesticides. 38 36th EPSA Annual Congress SPEAKERS EXTERNAL SPEAKERS Lilian M. Azzopardi Lilian M. Azzopardi is professor and head of department of pharmacy within the Faculty of Medicine and Surgery at the University of Malta. Professor Azzopardi co-ordinates the teaching of pharmacy practice and leads a research group in the areas of quality systems and clinical pharmacy interventions. She has spearheaded major developments in pharmacy education within the Department of Pharmacy of the University of Malta. She is the author of a number of textbooks and several research papers. She received research awards by FIP and ESCP. Professor Azzopardi is the General Secretary of the European Association of Faculties of Pharmacy. Andreia Bruno FIP Collaborating Centre UCL School of Pharmacy Andreia Bruno is a Project Coordinator and Researcher at the International Pharmaceutical Federation (FIP) Education Initiatives, a post she has held since January 2011. Her areas of responsibility encompass all issues relevant to communications and coordination plans for projects within the domain areas of the Development Team (Domains: Vision and Competency, Academic and Institutional Capacity, Quality Assurance, Pharmacy Support Workforce, Interprofessional Education, Continuing Professional Development/Education, and Leadership). Dr Bruno also provides editorial support to the Pharmacy Education research Journal, an online platform for publishing peer-review articles and manages the development of the FIP-UNESCO University Twinning Network for Pharmacists (Global Pharmacy Education Development (G-PhED) network. Filippo Drago Filippo Drago is Full Professor of Pharmacology at the Department of Clinical and Molecular Biomedicine of the University of Catania. He is Chairman of the Master of Regulatory Disciplines at the University of Catania. He is Member of the Italian Agency of Drug Evaluation. His research activity has been directed to different fields of pharmacology from ocular pharmacology to neuropsychopharmacology and focused on several topics such as endocannabinoids, neuropeptides, brain-endocrine interactions and the neurobiological basis and the pharmacological treatment of neuropsychiatric diseases such as Schizophrenia, Major Depression and Alzheimer’s disease.. Dr Roberto Frontini President, EAHP Affiliation: University Hospital of Leipzig Country: Germany 1. Current status, Position: Director of Pharmacy at the University Hospital of Leipzig 2. Career history: Catania | 22.04. - 28.04.2013 39 SPEAKERS • 1993-1995: Employed by University Hospital of Lübeck; • 1996-2001: Head of Pharmacy at St.Franziskus-Hospital,Cologne; • 2001-current: Director of Pharmacy at the University Hospital of Leipzig; • 2005-2009: Director of Finances of the European Association of Hospital Pharmacists (EAHP); • 2009-current: President of European Association of Hospital Pharmacists (EAHP). 3. Education: • 1983-1988: Pharmacy, University of Hamburg, Germany; • 1993: Phd in pharmaceutical technology, University of Hamburg, Germany; • 1996: Specialisation degree in Hospital Pharmacy. 4. Research interests: Patient safety 5. Other achievements: • 1994 to 2005: Served in a training position for pharmaceutical technology at the Chamber of Pharmacy Hannover; • 2004-current: Lectured on Pharmacoepidemiology and Economics at the University of Leipzig, School of Pharmacy. Clive G. Wilson Clive G. Wilson is the J. P. Todd Professor of Pharmaceutics at Strathclyde University and the immediate past-president of EUFEPS. Major areas of research have been the study of the behaviour of drug formulations in man. He is a consultant to several companies in pharmaceutical industries in Europe and in the USA. He has published more than 170 papers, seven books and over 100 reviews and has supervised 71 Ph.D. and 1 M.D. students. He was made a Fellow of the Controlled Release Society in June 2010 and an Eminent Fellow of the Academy of Pharmaceutical Sciences in September 2010. Heidi Jäntti Heidi Jäntti has almost ten years experience of student advocacy and lobbying from local and governmental level. At the moment she works as an student advocate in Finnish Pharmacists’ Association Giovanni Mancarella Involved in the European Antibiotic Awareness Day initiative since 2010, and project manager since 2012, Giovanni Mancarella works in the Public Health Capacity and Communication Unit at the European Centre for disease prevention and Control (ECDC) in Stockholm, Sweden. Before joining ECDC he worked in Brussels as Communications & Policy officer in PGEU (2006-2010) and in Luxembourg at the European Commission (Publications Office – OPOCE). A lawyer by training, he worked in various law firms in Italy, Germany and Belgium. He is an Italian national and was educated at the Universities of Parma and München. 40 36th EPSA Annual Congress SPEAKERS Sanziana Marcu Sanziana Marcu has joined the Government Affairs department of GlaxoSmithKline Consumer Healthcare as an IMP trainee in October 2012, and has continued working as a trainee with the Government Affairs team in Brussels since then. Previously, Sanziana has been the EPSA VicePresidents of External Affairs 2010/2011 and the EPSA Permanent Officer in the Pharmaceutical Group of the European Union in Brussels. Sanziana has received the Master of Pharmacy degree from the University of Medicine and Pharmacy in Bucharest and has been actively involved in EPSA and the national and local students association throughout her studies. Dominique L. Monnet Head of Programme, Antimicrobial Resistance & Healthcare-Associated Infections (ARHAI) European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden. Dr. Monnet received his degrees in pharmacy (PharmD) and clinical microbiology (PhD) from the University of Lyon, France, and then obtained further education as a hospital infection control specialist and epidemiologist. Before joining ECDC in 2007, he worked in French hospitals, at the US Centers for Disease Control and Prevention (1993-1995) and at the Danish Statens Serum Institut (1997-2007) where he was coordinating surveillance of antimicrobial resistance and antimicrobial consumption in humans in Denmark. His research interests include surveillance of antimicrobial resistance and antimicrobial consumption, the relationship between consumption of antimicrobials and resistance, and the factors that affect antimicrobial usage, both in hospitals and in primary care. Tony Payton Obtained his PhD from the University of Manchester and works in the field of molecular genetics and complex diseases. He has over 20 years genetics experience and has worked in multiple and diverse disease areas including rheumatoid arthritis, onchocerciasis, invasive pneumococcal disease, depression and ADHD. Over the past 12 years he has specialised in cognitive genetics with focus on the genetics of cognitive ability and decline in the elderly. He now leads an active cognitive genetics team at the University of Manchester which uses genome wide association and a variety of functional techniques. He also coordinates genetics research and development at Salford Royal NHS hospital. For the past 3 years he has worked within the IMI funded education and training research topic EMTRAIN. Here he has helped develop an online biomedical resource centre called on-course (www.on-course.eu) as well as chair both the on-course maintenance and development team and the “Gap analysis” team. Catania | 22.04. - 28.04.2013 41 SPEAKERS Patricia Pessoa Patricia Pessoa has recently joined the European Sales Team of GlaxoSmithKline Consumer Healthcare in London through IMP. After her graduation in 2012 (PharmD, Pharmaceutical Sciences at the Faculty of Pharmacy, University of Coimbra, Portugal) she had some short experiences as a trainee (marketing and clinical research associate). International and teamwork experience was always present trough her academic career: apart from being an active member of Pharmacy students associations at local and international level (NEF/AAC, APEF, IPSF) she studied for one year in Madrid through ERASMUS Programme and made a SEP summer internship in Riga, Latvia. Richard Price Richard has been the Policy and Advocacy Officer at EAHP since January 2012, in which role he focuses on a number of core policy areas including: promoting the development and patient safety need for hospital pharmacy specialisation; campaigning for the establishment of systematic bar-coding to the single unit of medicines for administration hospitals, in order to permit bedside scanning and checking at the point of administration; profiling the activity of hospital pharmacists in clinical trial research and promoting the need for greater transparency in result reporting; and raising awareness of the need for combined action to combat the growing experience in hospital pharmacy of medicines shortage. Francesco Scimó Managerial consultant, professional coach, rogerian counsellor and training consultant. Since 1996 he has provided training, coaching and consultancy across a range of managerial, psychological, and personal development related subjects to financial institutions and international companies such as Invesco, ABN Amro, Google, Computer Associate, Kennametal, SASOL, Cisco System, CSM, Boston Scientific and Shell. He is an NLP expert and the creator of Learning Revolution (a technology designed to provide those who need to study with the skills to speed up the learning process – and make the learning more permanent) and A Life Of Abundance (a personal development path toward self actualization). Wolf R. See Prof. Dr. DSc, MA (UCLA) Wolf R. See was born in Bad Homburg, Germany in 1946. He received his MA (Psychology), from University of California Los Angeles 1970; MSc (Diplombiologe) 1972, PhD (Dr. rer.nat.) 1976, DSc (Privatdozent of Physiology) 1984, Full Prof. of Physiology (apl.) 1992 from Ruhr-University Bochum (RUB), Germany. From 1984 to 1991 he was Visiting Asst. Prof. of Physiology, Albert Einstein College of Medicine (AECOM), New York, 42 36th EPSA Annual Congress SPEAKERS HEADER and since 1992 Visiting Prof. of Physiology. He joined pharmaceutical industry in 1988 and held various positions in clinical research, clinical operations, and regulatory affairs while continuing his basic research in respiratory physiology at AECOM and his teaching at RUB. Since his retirement from industry in 2005 he works as independent consultant and is at present heavily involved in IMI E&T projects. Jurate Svarcaite Pharmaceutical and Professional Affairs Advisor in Pharmaceutical Group of the European Union (PGEU) Ms Svarcaite is responsible for Pharmaceutical and Professional Affairs at PGEU. She has been working in PGEU since 2010. The Pharmaceutical Group of the European Union (PGEU) is the European Association representing community pharmacists in 32 European countries. Her main tasks encompass representation of PGEU in professional fora and contacts with members as well as with external parties; responsible for issues relevant to pharmacy practice, including the activities of the European Medicines Agency (EMA) and European Commission (EC), the PGEU activities on patient safety, pharmaceutical policy and e-health. Additional responsibility includes management of Professional Issues WG of PGEU. She is also a member of the DG CONNECT eHealth Stakeholder Group and EMA’s Healthcare Professionals Working Group. Belkıs Ünver Specialist Pharmacist, Marmara University Faculty of Pharmacy After graduating from faculty of pharmacy in 1972 in Istanbul, Pharmacist Belkıs Ünver worked in Abbott Pharmaceuticals, Quality Control Department for 4 years. She worked as research assistant in Marmara University Faculty of Dentistry, Division of Biochemistry between the years 1976-1985. She has been working in Marmara University Faculty of Pharmacy in Division of Pharmaceutical Care since 1985. Pharmacist Belkıs Ünver has been working for Marmara University Faculty of Pharmacy Alumni Association since its establishment and still, she is a member of its executive. Besides, she is also working for other Non-Governmental Organizations (NGO) and executives of other associations; she is a member of the Scholarship Comission and working for Social Responsibility Projects. Among to her specialty, she is working for Rottary and Innerwhell Club and consulting to victims of violence. Catania | 22.04. - 28.04.2013 43 HEADER SPEAKERS Lynda Wight Executive Director, TOPRA Lynda is a biologist who started her regulatory career in Merck Sharp & Dohme as Registration Manager. She then helped establish a consultancy and training company which grew to become a global CRO for which she was Executive VP for Europe. Following the sale of that company, Lynda took on the role of Executive Director for TOPRA , the professional association for regulatory specialists. She is a Fellow of the Royal Society of Medicine and Council member for the Pharmaceutical Section and Fellow and Board member of the Institute of Association Management. She has over 50 publications on aspects of clinical research and regulatory affairs. 44 36th EPSA Annual Congress NOTES Catania | 22.04. - 28.04.2013 45 SPONSORS University of Catania Comune di Catania Ordine dei Farmaisti RiKrea Aboca Der Katerkiller Germany Banca Agricola Popolare di Ragusa Benetton Superga Tomarchio Bibite Tomarchio dolciaria Fratelli Averna FENAGIFAR 46 36th EPSA Annual Congress MEET THE EPSA PEOPLE WHO ARE CONTRIBUTING HEADER TO THIS EDUCATIONAL PROGRAMME! Catania | 22.04. - 28.04.2013 47 HEADER Autumn A embly ss EPSA 1 0 th 2013 29 Oct - 3 Nov 48 36th EPSA Annual Congress