Life Sciences Organization Presentation

NXL Architects is one of Canada’s leading architects for the design of complex process buildings. The firm has 20 years and more than 4 million square feet experience in GMP, Laboratory and Vivaria facilities.
We are specialized. The firm has evolved since 1960, and the current partnership was formed in 1998. Since that time the firm has focused exclusively on the highly specialized research and production industry.
We design from the inside out. We g f
provide a tailored solution that ensures your building fits your specialized needs.
We compete on service. From concept to completion ‐ we are there for the project and the client from the very beginning to the very end.
the very beginning to the very end.
About NXL Architects
Expertise
Studies and Masterplans
Expertise
Programming
ORC Forensic Services 2007
Institutional Projects
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1. York U Life Sciences Building 2. Biovail Steinbach Expansion 3. UHN TMDT 4. Patheon Whitby 5. Hemosol Meadowpine Facility 6. York SHSRC
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Expertise
Full Scope Services
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1. UToronto Leslie L Dan Pharmacy Building
4. York U Life Sciences Building
2. Patheon Whitby
5. Syn X Discovery Labs
3 UHN TMDT @ MaRS
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UHN TMDT @ MaRS
6 York U SHSRC
6. York U SHSRC
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Expertise
Laboratory Design
Manufacturing Types
Design for Manufacturing & Equipment Installations
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Biopharmaceutical
Biologics
Monoclonal antibodies
Monoclonal antibodies
Mammalian & bacteria cell culture
Clean rooms
API manufacturing Contract manufacturing
Oral solid dosage/ penicillin
g /p
Liquids
Creams/ointments/gels
Sterile ophthalmic
Hormone manufacturing
Vaccines
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1. Patheon Whitby
2 Stuart Energy
2. Stuart Energy 3. Torcan Chemical Ltd.
4. UHN TMDT (NMR Room)
5. Alphora
6. Hemosol Inc
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Expertise
Facilities for Specialized Manufacturing and Equipment
Looking Ahead
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1. Hemosol
2 UHN Pathology
2. UHN Pathology
3. UHN TMDT Sterilization Suite
4. UHN TMDT Microarray
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Expertise
Specialized Environments
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1. SPECT 4. Animal Holding Room
2. Cage Racking
5. Tunnel Washer
3. Animal OR
6. CT Scanner
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Expertise
Vivaria – Multi‐Species
1. UHN TMDT
2. York U Life Sciences Building
3. UHN KDC
4. Merck Frosst at MaRS
5. UHN KDC
6. Biovail Steinbach
7. UHN TMDT
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Expertise
Environments for Interaction
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Alphora Research Inc.
Astra Zeneca Canada Inc. Avecia Biotechnology Aventis Pasteur Limited Bioniche
h Life Sciences Inc. f
Biovail Corp. Core Cryolabs
Credit Valley Hospital
Cytochroma Inc. Estee Lauder Companies
GeneNews
GlaxoSmithKline Hemosol
Merck Frosst Canada & Co. Microbix
Novocol Pharmaceuticals
Novopharm Ltd. •
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NPS Pharmaceuticals Office of the Chief Coroner of Ontario Ontario Institute for Cancer Research
Patheon Inc. Pfizer Canada Inc. f
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Smithsonian Institute
Stuart Energy Systems Syn X Pharma Inc. Taro Pharmaceuticals Teledyne‐Dalsa
Therapure
TM Biosciences Torcan Chemical Ltd. University Health Network University of British Columbia University of Toronto University of Windsor
York University
Clients
Looking Ahead
NXL works in both the public and private sector – taking lessons learned and top concerns from one area and applying to the other so that both sectors have the benefit of our expertise
Industry / Academic
CLIENTS
Astra Zeneca Canada Inc. Avecia Biotechnology Aventis Pasteur Limited Bioniche Life Sciences Inc. Biovail Corp. GlaxoSmithKline Merck Frosst Canada & Co. Novopharm Ltd. Ltd
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1. Novopharm Ltd.
2. Patheon Inc.
3. Glaxo Smith Kline
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Pharmaceutical Projects
Hemosol
2003
Looking Ahead
Therapure
2011
Hemosoll
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2001
ORC/OAHPP Programming and Planning Study
Commercial Scale Facility Projects
SYN X Pharma
R&D Facility
Looking Ahead
2005
Gutted
2011
ORC/OAHPP Programming and Planning Study
Commercial Scale Facility Projects
Cytochroma Inc R&D Facility
Looking Ahead
2004
Vacated
2011
Queen St West Commercial Development
ORC/OAHPP Programming and Planning Study
Commercial Scale Facility Projects
Looking Ahead
GeneNews R&D Facility
2007
Downsized
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2010
Queen St West Commercial Development
ORC/OAHPP Programming and Planning Study
Commercial Scale Facility Projects
Alphora Kilo Lab / Pilot Plant / Masterplanning
Looking Ahead
2009 / 2011
Commercial Scale Facility Projects
University of Toronto Faculty of Pharmacy 2005
Institutional Projects
UHN Pathology
2005
Institutional Projects
UHN TORONTO MEDICAL UHN
TORONTO MEDICAL
DISCOVERY TOWER
2006
Institutional Projects
NPS 2005
OICR
2008
Institutional Projects
Sherman Health Sciences Research Centre
York University
2010
50,000 sf $11.5M Adaptive Reuse / Full Interior Reno / New Entrance / New Mezzanine / Multiple User Groups Institutional Projects
Credit Valley
2011
Institutional Projects
Life Sciences Building
York University
2011
200,000 sf $66M New Build / Fast Track Schedule
Research & Teaching Labs/ Public Spaces / Part of existing campus
Institutional Projects
Krembil Discovery Centre at Toronto Western
University Health Network
2013
Overall Project
330 000 sf $118M 330,000 sf
$118M
Research Component 175,000 sf $45M (approx)
Fit‐out of Research and Collaborative Areas Programming, Design and Construction
and Construction
Institutional Projects
Attracting research to Toronto
TBI 2003
MaRS Tower A
• NA’s largest combined bio‐medical cluster
Looking Ahead
• pharmaceutical
pharmaceutical, medical research, medical research
biotechnology, medical devices, medical surgical supply, and medical assistive technologies. • Employs 140,000.
• NA’s 4th largest medical research community
• 9,000 principal researchers and technicians
• 37
37 research institutes and 9 teaching h i tit t
d 9 t hi
hospitals.
• TO’s biotechnology cluster ranked among the world’s top 10.
• Pharmaceutical industry in the GTA employs 11,000.
• Sanofi Pasteur facility produces and ships vaccines to over 90 countries
vaccines to over 90 countries.
ORC/OAHPP Programming and Planning Study
Where we are now
Toronto’s “Discovery District”
Toronto’s “Discovery District”
• Research
Research spin
spin‐off
off
• Post‐incubator / pre‐commercial scale
• Life science real estate industry
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