MRI of the Acute Abdomen: Cost-effective use for the
Transcription
MRI of the Acute Abdomen: Cost-effective use for the
MRI of the Acute Abdomen: Cost-effective use for the Emergency Room Patient Diego R. Mar,n, M.D., Ph.D. The Cosden Professor and Chairman Department of Medical Imaging University of Arizona College of Medicine Tucson [email protected] Emergency Room Care Ø ED utilization of healthcare has increased significantly across the United States Ø 1996: 90.3 million ED visits Ø 2006: 119.2 million ED visits Ø Increase of 32% Ø Imaging ordered at 44% of all visits Ø CT ordered at 11.6% of visits Pitts, S. R., R. W. Niska, et al. (2008). "National Hospital Ambulatory Medical Care Survey: 2006 emergency department summary." Natl Health Stat Report(7): 1-38. MRI for Acute Abdominal Pain Proposed Advantages Ø Reduce radiation exposure in young patients Ø Increase ED throughput (no oral or IV contrast) Ø Decrease total no. of tests (XR + US + CT) Ø Increase value (Outcome / Cost) Strategy Ø Patients <40yo with acute abdominal pain (excluding renal calculus) Ø Outcomes monitored (including d/c patients) Cor T2 Ax T2 T1W 3D GRE FS (Dixon) Cor T2 FS Sag T2 Ax T2 FS Out of phase (Dixon) Sag T2 FS SSFP MRCP In phase (Dixon) Fat suppressed 3D T1W (Dixon- Water only) 3D T1W Dual echo GRE (Dixon- In and opposed phase) -Blood products -Proteinaceous material -Fat (loss of signal on opposed phase) -Iron (loss of signal on in phase) T2W (motion resistant) -Assessment of fluid containing structures -Organ morphology T2W (motion resistant) with fat saturation -Acute inflammation (itis sequence) -Fat (dermoid, lipoma) True FISP (motion resistant) MRCP -Vascular analysis (noncontrast) -Secondary analysis of fluid containing structures -Bile ducts -Fluid containing structures MRI Interpretation Strategy T2-weighted images without fat saturation Ø Coronal, sagittal and axial ANATOMY T2-weighted images with fat saturation (SPAIR technique) Ø Coronal, sagittal and axial INFLAMMATION 18 yo F, acute appendicitis Ax T2 Ax T2 FS 34 yo F, pregnant, RLQ pain from appendicitis 28 yo F, pregnant, RLQ pain from ovarian torsion MRI Interpretation Strategy Unenhanced 3D GRE Fat-Suppressed (VIBE, LAVA, THRIVE) Blood Products Hemorrhagic ovarian cyst 73 yo M, dropping H&H A Cross-Section of Cases Showing An Array of Disease Processes Spanning GI and Non-GI Etiologies 25 yo M with RLQ pain 25 yo M with RLQ pain from acute appendicitis 15 yo M, diffuse abdominal pain 15 yo M, diffuse abdominal from perforated appendicitis 9 yo male, RLQ pain from appendicitis 22y M: Abdominal Pain Time: 10:02 am 22y M: Abdominal Pain Enteritis Time: 11:50 am Time: 10:02 am 19 yo M, recurrent RLQ pain Negative Meckel scan Meckel’s diverticulum 20y F with abdominal pain Pyelonephritis 66 yo F, acute appendicitis Incidental Meckel’s Diverticulum 63y M, LLQ pain Acute Diverticulitis 42 yo F, POD 11, fever & abdo pain Bowel perforation and peritonitis 22 yo F, pelvic pain 22 yo F, tubo-ovarian abscess 20 yo F, pelvic pain Pelvic inflammatory disease 27 yo F, RUQ pain Acute cholecystitis 65 yo F, RUQ pain Acute cholecystitis 15 yo F, RUQ pain Acute hepatitis, with GB wall edema 26 yo F, LLQ pain Ovarian torsion Rectus muscle strain 40 yo M, abdominal pain Pyelonephritis, bilateral 24 yo F Pyelonephritis, hepatitis, LOV cyst 15 yo F, lower abdominal pain Results Ø Over 16 months (8.12 to 12.13) Ø 234 patients mean age 21.8y Ø 18% confirmed positive pathology Ø MRI prospective findings Ø 0 (0%) false negative Ø 1 (0.4% or 5% in surgical cases) false positive Precision of MRI – Published results Ø Cobben L, Groot I, Kingma L, Coerkamp E, Puylaert J and Blickman J. A simple MRI protocol in patients with clinically suspected appendicitis: results in 138 patients and effect on outcome of appendectomy. Eur Radiol 2009; 19(5):1175-1183 Ø Singh AK, Desai H and Novelline RA. Emergency MRI of acute pelvic pain: MR protocol with no oral contrast. Emerg Radiol 2009; 16(2):133-141 Ø Inci E, Hocaoglu E, Aydin S, et al. Efficiency of unenhanced MRI in the diagnosis of acute appendicitis: comparison with Alvarado scoring system and histopathological results. Eur J Radiol 2011; 80(2):253-258 Ø Chabanova E, Balslev I, Achiam M, et al. Unenhanced MR Imaging in adults with clinically suspected acute appendicitis. Eur J Radiol 2011; 79(2):206-210 Ø Heverhagen JT, Pfestroff K, Heverhagen AE, Klose KJ, Kessler K and Sitter H. Diagnostic accuracy of magnetic resonance imaging: a prospective evaluation of patients with suspected appendicitis (diamond). J Magn Reson Imaging 2012; 35(3): 617-623 Ø Johnson AK, Filippi CG, Andrews T, et al. Ultrafast 3-T MRI in the evaluation of children with acute lower abdominal pain for the detection of appendicitis. AJR Am J Roentgenol 2012; 198(6):1424-1430 Summary Ø MRI provides competitive turnaround time c/w CT for ED patients Ø Increased sensitivity and specificity Ø Utility dependent upon center availability and skillsets available 24x7