Publication List 2015 - PuSH - Publikationsserver des Helmholtz

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Publication List 2015 - PuSH - Publikationsserver des Helmholtz
31.12.2015
Publication List 2015
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joint first authors
° corresponding authors
HMGU authors are given in bold letters
Sustainable Plant Production
Allan, E.°, Manning, P., Alt, F., Binkenstein, J., Blaser, S., Blüthgen, N., Böhm, S., Grassein, F., Hölzel, N.,
Klaus, V.H., Kleinebecker, T., Morris, E.K., Oelmann, Y., Prati, D., Renner, S.C., Rillig, M.C., Schaefer, M.,
Schloter, M., Schmitt, B., Schöning, I., Schrumpf, M., Solly, E., Sorkau, E., Steckel, J., Steffen-Dewenter, I.,
Stempfhuber, B., Tschapka, M., Weiner, C.N., Weisser, W.W., Werner, M., Westphal, C., Wilcke, W.,
Fischer, M.: Land use intensification alters ecosystem multifunctionality via loss of biodiversity and changes
to functional composition. Ecol. Lett. 18, 834-843 (2015)
Alter, S., Bader, K.C., Spannagl, M., Wang, Y., Bauer, E., Schön, C.C., Mayer, K.F.X.°: DroughtDB: An
expert-curated compilation of plant drought stress genes and their homologs in nine species. Database
(Oxford) 2015:bav046 (2015)
Bi, Z., Merl-Pham, J., Uehlein, N., Zimmer, I., Mühlhans, S., Aichler, M., Walch, A.K., Kaldenhoff, R.,
Palme, K., Schnitzler, J.-P., Block, K.°: RNAi-mediated downregulation of poplar Plasma membrane
Intrinsic Proteins (PIPs) changes plasma membrane proteome composition and affects leaf physiology. J.
Proteomics 128, 321-332 (2015)
Bourdais, G.#, Burdiak, P.#, Gauthier, A.#, Nitsch, L.#, Salojärvi, J.#, Rayapuram, C.#, Idänheimo, N., Hunter,
K., Kimura, S., Merilo, E., Vaattovaara, A., Oracz, K., Kaufholdt, D., Pallon, A., Anggoro, D.T., Glow, D.,
Lowe, J., Zhou, J., Mohammadi, O., Puukko, T., Albert, A., Lang, H., Ernst, D., Kollist, H., Brosché, M.,
Durner, J., Borst, J.W., Collinge, D.B., Karpiński, S., Lyngkjær, M.F., Robatzek, S., Wrzaczek, M.°,
Kangasjärvi, J.: Large-scale phenomics identifies primary and fine-tuning roles for CRKs in responses
related to oxidative stress. PLoS Genet. 11:e1005373 (2015)
Braun, P., Grass, G.°, Aceti, A., Serrecchia, L., Affuso, A., Marino, L., Grimaldi, S., Pagano, S., Hanczaruk,
M., Georgi, E., Northoff, B., Schöler, A., Schloter, M., Antwerpen, M., Fasanella, A.: Microevolution of
Anthrax from a Young Ancestor (MAYA) suggests a soil-borne life cycle of Bacillus anthracis. PLoS ONE
10:e0135346 (2015)
Byrne, S.L., Pfeifer, M., Nagy, I., Armstead, I., Swain, S., Studer, B., Mayer, K.F.X., Campbell, J.D., Czaban,
A., Hentrup, S., Panitz, F., Bendixen, C., Hedegaard, J., Caccamo, M., Asp, T.°: A synteny-based draft
genome sequence of the forage grass Lolium perenne. Plant J. 84, 816-826 (2015)
Cantarel, A.A.°, Pommier, T., Desclos-Theveniau, M., Diquelou, S., Dumont, M., Grassein, F., Kastl, E.-M.,
Grigulis, K., Laine, P., Lavorel, S., Lemauviel-Lavenant, S., Personeni, E., Schloter, M., Poly, F.: Using plant
traits to explain plant–microbe relationships involved in nitrogen acquisition. Ecology 96, 788-799 (2015)
Chaki, M., Shekariesfahlan, A., Ageeva, A., Mengel, A., von Toerne, C., Durner, J., Lindermayr, C.°:
Identification of nuclear target proteins for S-nitrosylation in pathogen-treated Arabidopsis thaliana cell
cultures. Plant Sci. 238, 115-126 (2015)
Chalal, M., Winkler, J.B., Gourrat, K., Trouvelot, S., Adrian, M.V., Schnitzler, J.-P., Jamois, F., Daire, X.°:
Sesquiterpene Volatile Organic Compounds (VOCs) are markers of elicitation by sulfated laminarine in
grapevine. Front. Plant Sci. 6:350 (2015)
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31.12.2015
Publication List 2015
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joint first authors
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HMGU authors are given in bold letters
Sustainable Plant Production
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Chen, Z. , Wang, C. , Gschwendtner, S., Willibald, G., Unteregelsbacher, S., Lu, H., Kolar, A., Schloter,
M., Butterbach-Bahl, K., Dannenmann, M.°: Relationships between denitrification gene expression,
dissimilatory nitrate reduction to ammonium and nitrous oxide and dinitrogen production in montane
grassland soils. Soil Biol. Biochem. 87, 67-77 (2015)
Chowdhury, S.P., Hartmann, A., Gao, X., Borriss, R.°: Biocontrol mechanism by root-associated Bacillus
amyloliquefaciens FZB42 - a review. Front. Microbiol. 6:780 (2015)
Chowdhury, S.P.°, Uhl, J., Grosch, R., Alqueres, S., Pittroff, S., Dietel, K., Schmitt-Kopplin, P., Borriss,
R., Hartmann, A.: Cyclic lipopeptides of Bacillus amyloliquefaciens subsp. plantarum colonizing the lettuce
rhizosphere enhance plant defence responses towards the bottom rot pathogen Rhizoctonia solani. Mol.
Plant Microbe Interact. 28, 984-995 (2015)
Chronakova, A.°, Schloter-Hai, B., Radl, V., Endesfelder, D., Quince, C., Elhottova, D., Simek, M.,
Schloter, M.: Response of archaeal and bacterial soil communities to changes associated with outdoor
cattle overwintering. PLoS ONE 10:e0135627 (2015)
Cui, H., Hense, B.A., Müller, J., Schröder, P.°: Short term uptake and transport process for metformin in
roots of Phragmites australis and Typha latifolia. Chemosphere 134, 307-312 (2015)
Cvikova, K., Cattonaro, F., Alaux, M., Stein, N., Mayer, K.F.X., Dolezel, J., Bartos, J.°: High-throughput
physical map anchoring via BAC-pool sequencing. BMC Plant Biol. 15:99 (2015)
Czaban, A., Sharma, S., Byrne, S.L., Spannagl, M., Mayer, K.F.X., Asp, T.°: Comparative transcriptome
analysis within the Lolium/Festuca species complex reveals high sequence conservation. BMC Genomics
16:249 (2015)
de Vega, J.J.°, Ayling, S., Hegarty, M., Kudrna, D., Goicoechea, J.L., Ergon, A., Rognli, O.A., Jones, C.,
Swain, M., Geurts, R., Lang, C., Mayer, K.F.X., Rössner, S., Yates, S., Webb, K.J., Donnison, I.S., Oldroyd,
G.E., Wing, R.A., Caccamo, M., Powell, W., Abberton, M.T., Skøt, L.°: Red clover (Trifolium pratense L.)
draft genome provides a platform for trait improvement. Sci. Rep. 5:17394 (2015)
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de Vries, M.C. , Schöler, A. °, Ertl, J., Xu, Z., Schloter, M.: Metagenomic analyses reveal no differences in
genes involved in cellulose degradation under different tillage treatments. FEMS Microbiol. Ecol. 91:fiv069
(2015)
Dey, S., Vlot, A.C.°: Ethylene responsive factors in the orchestration of stress responses in
monocotyledonous plants. Front. Plant Sci. 6:640 (2015)
Dietzel, L., Gläßer, C., Liebers, M., Hiekel, S., Courtois, F., Czarnecki, O., Schlicke, H., Zubo, Y., Börner, T.,
Mayer, K.F.X., Grimm, B., Pfannschmidt, T.°: Identification of early nuclear target genes of plastidial redox
signals that trigger the long-term response of Arabidopsis to light quality shifts. Mol. Plant 8, 1237–1252
(2015)
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HMGU authors are given in bold letters
Sustainable Plant Production
Ditengou, F.A., Müller, A., Rosenkranz, M., Felten, J., Lasok, H., van Doorn, M.M., Legué, V., Palme, K.°,
Schnitzler, J.-P.°, Polle, A.°: Volatile signalling by sesquiterpenes from ectomycorrhizal fungi reprogrammes
root architecture. Nat. Commun. 6:6279 (2015)
Dong, F., Simon, J.°, Rienks, M., Lindermayr, C., Rennenberg, H.: Effects of rhizopheric Nitric Oxide (NO)
on N uptake in Fagus sylvatica seedlings depend on soil CO2 concentration, soil N availability and N source.
Tree Physiol. 35, 910-920 (2015)
Ehrlich, R., Schulz, S., Schloter, M.°, Steinberger, Y.: Effect of slope orientation on microbial community
composition in different particle size fractions from soils obtained from desert ecosystems. Biol. Fertil. Soils
51, 507-510 (2015)
Eibisch, N., Schroll, R.°, Fuß, R.: Effect of pyrochar and hydrochar amendments on the mineralization of
the herbicide isoproturon in an agricultural soil. Chemosphere 134, 528-535 (2015)
Forczek, S.T.°, Laturnus, F., Doležalová, J., Holík, J., Wimmer, Z.: Emission of climate relevant volatile
organochlorines by plants occurring in temperate forests. Plant Soil Environ. 61, 103-108 (2015)
Frank, U., Ernst, D.: Ein "neues" Kraut mit hohem allergenen Potenzial. Dtsch. Ärztebl. 2, 25-27 (2015)
Frank, U.°, Ernst, D.: Klimafaktoren – welche Effekte haben sie auf die Allergenität von Pollen? Allergologie
38, 597-603 (2015)
Garrett, R.A.°, Shah, S.A., Erdmann, S., Liu, G., Mousaei, M., León-Sobrino, C., Peng, W.M.,
Gudbergsdottir, S., Deng, L., Vestergaard, G., Peng, X., She, Q.: CRISPR-Cas adaptive immune systems of
the sulfolobales: Unravelling their complexity and diversity. Life 5, 783-817 (2015)
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Glaeser, S.P. °, Imani, J. , Alabid, I. , Guo, H. , Kumar, N., Kämpfer, P., Hardt, M., Blom, J., Goesmann, A.,
Rothballer, M., Hartmann, A.°, Kogel, K.-H.°: Non-pathogenic Rhizobium radiobacter F4 deploys plant
beneficial activity independent of its host Piriformospora indica. ISME J. 10, 871-884 (2016) [published online
2015]
Götz-Rösch, C.#, Sieper, T.#, Fekete, A., Schmitt-Kopplin, P., Hartmann, A., Schröder, P.°: Influence of
bacterial N-acyl-homoserine lactones on growth parameters, pigments, antioxidative capacities and the
xenobiotic phase II detoxification enzymes in barley and yam bean. Front. Plant Sci. 6:205 (2015)
Haberer, G., Mayer, K.F.X.°: Barley: From brittle to stable harvest. Cell 162, 469-471 (2015)
Hartmann, A., Albert, A., Ganzera, M.°: Effects of elevated ultraviolet radiation on primary metabolites in
selected alpine algae and cyanobacteria. J. Photochem. Photobiol. B-Biol. 149, 149-155 (2015)
Helguera, E., Rivarola, M., Clavijo, B.J., Martis, M.M., Vanzetti, L.S., González, S., Garbus, I., Leroy, P.,
Simková, H., Valárik, M., Caccamo, M., Dolezel, J., Mayer, K.F.X., Feuillet, C., Tranquilli, G.E.°, Paniego,
N.B.°, Echenique, V.C.°: New insights into the wheat chromosome 4D structure and virtual gene order,
revealed by survey pyrosequencing. Plant Sci. 233, 200-212 (2015)
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HMGU authors are given in bold letters
Sustainable Plant Production
Jha, B.°, Singh, V.K., Weiss, A., Hartmann, A., Schmid, M.: Zhihengliuella somnathii sp. nov., a
halotolerant actinobacterium from the rhizosphere of a halophyte Salicornia brachiata. Int. J. Syst. Evol.
Microbiol. 65, 3137-3142 (2015)
Jud, W., Vanzo, E., Li, Z., Ghirardo, A., Zimmer, I., Sharkey, T.D., Hansel, A.°, Schnitzler, J.-P.: Effects of
heat and drought stress on post illumination bursts of volatile organic compounds in isoprene emitting and
non-emitting poplar. Plant Cell Environ., DOI: 10.1111/pce.12643 (2015)
Kaurin, A., Mihelic, R., Kastelec, D., Schloter, M., Suhaldoc, M., Grčman, H.°: Consequences of minimum
soil tillage on abiotic soil properties and composition of microbial communities in a shallow Cambisol
originated from fluvioglacial deposits. Biol. Fertil. Soils 51, 923-933 (2015)
Kovacs, I., Durner, J., Lindermayr, C.°: Crosstalk between nitric oxide and glutathione is required for
NONEXPRESSOR OF PATHOGENESIS-RELATED GENES 1 (NPR1)-dependent defense signaling in
Arabidopsis thaliana. New Phytol. 208, 860-872 (2015)
Leberecht, M., Dannenmann, M., Gschwendtner, S., Bilela, S., Meier, R., Simon, J., Rennenberg, H.,
Schloter, M., Polle, A.°: Ectomycorrhizal communities on the roots of two beech (Fagus sylvatica)
populations from contrasting climate differ in nitrogen acquisition in a common environment. Appl. Environ.
Microbiol. 81, 5957-5967 (2015)
Lehotai, N.°, Lyubenova, L., Schröder, P., Feigl, G., Ördög, A., Szilágyi, K., Erdei, L., Kolbert, Z.:
Nitro-oxidative stress contributes to selenite toxicity in pea (Pisum sativum L). Plant Soil 400, 107-122 (2016)
[published online 2015]
Leiber-Sauheitl, K.°, Fuß, R., Burkart, S., Buegger, F., Dänicke, S., Meyer, U.E., Petzke, K.J., Freibauer, A.:
Sheep excreta cause no positive priming of peat-derived CO2 and N2O emissions. Soil Biol. Biochem. 88,
282-293 (2015)
Lutz, U., Posé, D., Pfeifer, M., Gundlach, H., Hagmann, J., Wang, C., Weigel, D., Mayer, K.F.X., Schmid,
M., Schwechheimer, C.°: Modulation of ambient temperature-dependent flowering in Arabidopsis thaliana by
natural variation of FLOWERING LOCUS M. PLoS Genet. 11:e1005588 (2015)
Lyubenova, L.°, Sabodash, X., Schröder, P., Michalke, B.: Selenium species in the roots and shoots of
chickpea plants treated with different concentrations of sodium selenite. Environ. Sci. Pollut. Res. 22,
16978-16986 (2015)
Mai, H.J., Lindermayr, C., von Toerne, C., Fink-Straube, C., Durner, J., Bauer, P.°: Iron and FER-LIKE
IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (FIT)-dependent regulation of proteins and
genes in Arabidopsis thaliana roots. Proteomics 15, 3030-3047 (2015)
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Mathew, L.S. , Seidel, M. , George, B., Mathew, S., Spannagl, M., Haberer, G., Torres, M.F., Al-Dous, E.K.,
Al-Azwani, E.K., Diboun, I., Krueger, R.R., Mayer, K.F.X., Mohamoud, Y.A., Suhre, K., Malek, J.A.°: A
genome-wide survey of date palm cultivars supports two major subpopulations in Phoenix dactylifera. Genes
Genomes Genetics G3 5, 1429-1438 (2015)
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HMGU authors are given in bold letters
Sustainable Plant Production
Müller, A., Kaling, M., Faubert, P., Gort, G., Smid, H.M., van Loon, J.J., Dicke, M., Kanawati, B.,
Schmitt-Kopplin, P., Polle, A., Schnitzler, J.-P., Rosenkranz, M.°: Isoprene emission by poplar is not
important for the feeding behaviour of poplar leaf beetles. BMC Plant Biol. 15:165 (2015)
Niederbacher, B., Winkler, J.B., Schnitzler, J.-P.°: Volatile organic compounds as non-invasive markers
for plant phenotyping. J. Exp. Bot. 66, 5403-5416 (2015)
Nussbaumer, T., Warth, B., Sharma, S., Ametz, C., Bueschl, C., Parich, A., Pfeifer, M., Siegwart, G.,
Steiner, B., Lemmens, M., Schuhmacher, R., Buerstmayr, H., Mayer, K.F.X., Kugler, K.G.°, Schweiger, W.°:
Joint tanscriptomic and metabolomic analyses reveal changes in the primary metabolism and imbalances in
the subgenome orchestration in the bread wheat molecular response to Fusarium graminearum. Genes
Genomes Genetics G3 5, 2579-2592 (2015)
Obermeier, M., Schröder, C.A., Helmreich, B., Schröder, P.°: The enzymatic and antioxidative stress
response of Lemna minor to copper and a chloroacetamide herbicide. Environ. Sci. Pollut. Res. 22,
18495-18507 (2015)
Oeder, S.°, Alessandrini, F., Wirz, O.F., Braun, A., Wimmer, M., Frank, U., Hauser, M., Durner, J.,
Ferreira, F., Ernst, D., Mempel, M., Gilles, S., Buters, J.T.M., Behrendt, H., Traidl-Hoffmann, C.,
Schmidt-Weber, C.B., Akdis, M., Gutermuth, J.°: Pollen-derived non-allergenic substances enhance
Th2-induced IgE production in B cells. Allergy 70, 1450-1460 (2015)
Palacios, O.A., Bashan, Y., Schmid, M., Hartmann, A., de-Bashan, L.E.°: Enhancement of thiamine release
during synthetic mutualism between Chlorella sorokiniana and Azospirillum brasilense growing under stress
conditions. J. Appl. Phycol., DOI: 10.1007/s10811-015-0697-z (2015)
Permyakov, A., Osipova, S., Bondarenko, N., Obolkina, L., Timoshkin, O., Boedeker, C., Geist, B.,
Schäffner, A.: Proteins homologous to aquaporins of higher plants in the freshwater alga Ulothrix zonata
(Ulotrichales, Chlorophyta). Eur. J. Phycol. 51, 99-106 (2015)
Poursarebani, N., Seidensticker, T., Koppolu, R., Trautewig, C., Gawroński, P., Bini, F., Govind, G., Rutten,
T., Sakuma, S., Tagiri, A., Wolde, G.M., Youssef, H.M., Battal, A., Ciannamea, S., Fusca, T., Youssef, H.M.,
Nussbaumer, T., Pozzi, C., Börner, A., Lundqvist, U., Komatsuda, T., Salvi, S., Tuberosa, R., Uauy, C.,
Sreenivasulu, N., Rossini, L., Schnurbusch, T.°: The genetic basis of composite spike form in barley and
"Miracle-Wheat". Genetics 201, 155-165 (2015)
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Purahong, W. °, Kapturska, D. , Pecyna, M.J. , Jariyavidyanont, K., Kaunzner, J., Juncheed, K.,
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Uengwetwanit, T., Rudloff, R., Schulz, E., Hofrichter, M., Schloter, M., Kruger, D. , Buscot, F.°: Effects of
forest management practices in temperate beech forests on bacterial and fungal communities involved in leaf
litter degradation. Microb. Ecol. 69, 905-913 (2015)
Purahong, W.#°, Stempfhuber, B.#, Lentendu, G.#, Francioli, D., Reitz, T., Buscot, F., Schloter, M.°, Krüger,
D.: Influence of commonly used primer systems on automated ribosomal intergenic spacer analysis of
bacterial communities in environmental samples. PLoS ONE 10:e0118967 (2015)
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HMGU authors are given in bold letters
Sustainable Plant Production
Qanbari, S., Seidel, M., Strom, T.M., Mayer, K.F.X., Preisinger, R., Simianer, H.: Parallel selection revealed
by population sequencing in chicken. Genome Biol. Evol. 7, 3299-3306 (2015)
Radl, V.°, Kindler, R., Welzl, G., Albert, A., Wilke, B.M., Amelung, W., Schloter, M.: Drying and rewetting
events change the response pattern of nitrifiers but not of denitrifiers to the application of manure containing
antibiotic in soil. Appl. Soil Ecol. 95, 99-106 (2015)
Rothballer, M., Picot, M., Sieper, T., Arends, J.B., Schmid, M., Hartmann, A., Boon, N., Buisman, C.,
Barrière, F., Strik, D.P.°: Monophyletic group of unclassified γ-Proteobacteria dominates in mixed culture
biofilm of high-performing oxygen reducing biocathode. Bioelectrochem. 106, 167-176 (2015)
Sauvetre, A., Schröder, P.°: Uptake of carbamazepine by rhizomes and endophytic bacteria of Phragmites
australis. Front. Plant Sci. 6:83 (2015)
Scheler, C., Weitbrecht, K., Pearce, S.P., Hampstead, A., Büttner-Mainik, A., Lee, K.J.D., Voegele, A.,
Oracz, K., Dekkers, B.J.W., Wang, X., Wood, A.T.A., Bentsink, L., King, J.R., Knox, J.P., Holdsworth, M.J.,
Müller, K.B., Leubner-Metzger, G.°: Promotion of testa rupture during garden cress germination involves
seed compartment-specific expression and activity of pectin methylesterases. Plant Physiol. 167, 200-215
(2015)
Schimek, M.G.°, Budinska, E., Kugler, K.G., Svendova, V., Ding, J., Lin, S.: TopKLists: A comprehensive R
package for statistical inference, stochastic aggregation, and visualization of multiple omics ranked lists. Stat.
Appl. Genet. Mol. Biol. 14, 311-316 (2015)
Schloter, M.°, Kostric, M., Schöler, A., Treichel, N., Krauss-Etschmann, S., Berg, G.: Die Bedeutung des
humanen Mikrobioms für die menschliche Gesundheit. BIOspektrum 21, 39-40 (2015)
Schuerings, J.°, Jentsch, A., Hammerl, V., Lenz, K., Henry, H.A.L., Malyshev, A.V., Kreyling, J.: Increased
winter soil temperature variability enhances nitrogen cycling and soil biotic activity in temperate heathland
and grassland mesocosms. Biogeosciences 11, 7051-7060 (2014)
Silvar, C., Martis, M.M., Nussbaumer, T., Haag, N., Rauser, R., Keilwagen, J., Korzun, V., Mayer, K.F.X.,
Ordon, F., Perovic, D.: Assessing the barley genome zipper and genomic resources for breeding purposes.
Plant Genome 8, DOI: 10.3835/plantgenome2015.06.0045 (2015)
Spannagl, M.#°, Nussbaumer, T.#, Bader, K.C.#, Martis, M.M., Seidel, M., Kugler, K.G., Gundlach, H.,
Mayer, K.F.X.: PGSB PlantsDB: Updates to the database framework for comparative plant genome
research. Nucleic Acids Res. 44, D1141-D1147 (2016) [published online 2015]
Spannagl, M., Bader, K.C., Pfeifer, M., Nussbaumer, T., Mayer, K.F.X.°: PGSB/MIPS plant genome
information resources and concepts for the analysis of complex grass genomes. Methods Mol. Biol. 1374,
165-186 (2016)
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HMGU authors are given in bold letters
Sustainable Plant Production
Spannagl, M., Alaux, M., Lange, M., Bolser, D., Bader, K., Letellier, T., Kimmel, E., Flores, R., Pommier, C.,
Kerhornou, A., Walts, B., Nussbaumer, T., Grabmuller, C., Chen, J., Colmsee, C., Beier, S., Mascher, M.,
Schmutzer, T., Arend, D., Thanki, A., Ramirez-Gonzalez, R.H., Ayling, M., Ayling, S., Caccamo, M., Mayer,
K.F.X., Scholz, U., Steinbach, D., Quesneville, H., Kersey, P.°: Transplant resources for Triticeae genomic
data. Plant Genome 9, DOI: 10.3835/plantgenome2015.06.0038 (2015)
Spohn, M.°, Treichel, N., Cormann, M., Schloter, M., Fischer, D.: Distribution of phosphatase activity and
various bacterial phyla in the rhizosphere of Hordeum vulgare L. depending on P availability. Soil Biol.
Biochem. 89, 44-51 (2015)
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Steinbach, A. , Schulz, S. , Giebler, J., Schulz, S., Pronk, G.J., Kögel-Knabner, I., Harms, H., Wick, L.Y.,
Schloter, M.°: Clay minerals and metal oxides strongly influence the structure of alkane-degrading microbial
communities during soil maturation. ISME J. 9, 1687-1691 (2015)
Stempfhuber, B., Engel, M., Fischer, D., Neskovic-Prit, G., Wubet, T., Schöning, I., Gubry-Rangin, C.,
Kublik, S., Schloter-Hai, B., Rattei, T., Welzl, G., Nicol, G.W., Schrumpf, M., Buscot, F., Prosser, J.I.,
Schloter, M.°: pH as a driver for ammonia-oxidizing Archaea in forest soils. Microb. Ecol. 69, 879-883 (2015)
Stets, M.I., Alqueres, S., Souza, E.M., Pedrosa, F.O., Schmid, M., Hartmann, A., Cruz, L.M.°:
Quantification of Azospirillum brasilense FP2 in wheat roots by strain-specific qPCR. Appl. Environ.
Microbiol. 81, 6700-6709 (2015)
Tedersoo, L.°, Bahram, M., Cajthaml, T., Polme, S., Hiiesalu, I., Anslan, S., Harend, H., Buegger, F.,
Pritsch, K., Koricheva, J., Abarenkov, K.: Tree diversity and species identity effects on soil fungi, protists
and animals are context dependent. ISME J. 10, 346-362 (2015)
Teschner, D.°, Rieger, M., Koopman, C., Gehlen, H.: Procalcitonin in horses with an acute colic.
Pferdeheilkunde 31, 377-385 (2015)
Uksa, M., Schloter, M.°, Endesfelder, D., Kublik, S., Engel, M., Kautz, T., Köpke, U., Fischer, D.:
Prokaryotes in subsoil - evidence for a strong spatial separation of different phyla by analysing
co-occurrence networks. Front. Microbiol. 6:1269 (2015)
Uksa, M., Schloter, M.°, Kautz, T., Athmann, M., Köpke, U., Fischer, D.: Spatial variability of hydrolytic and
oxidative potential enzyme activities in different subsoil compartments. Biol. Fertil. Soils 51, 517-521 (2015)
Unterholzner, S.J., Rozhon, W., Papacek, M., Ciomas, J., Lange, T., Kugler, K.G., Mayer, K.F.X., Sieberer,
T., Poppenberger, B.°: Brassinosteroids are master regulators of gibberellin biosynthesis in arabidopsis.
Plant Cell 27, 2261-2272 (2015)
Vanzo, E., Jud, W., Li, Z., Albert, A., Domagalska, M.A., Ghirardo, A., Niederbacher, B., Frenzel, J.,
Beemster, G.T., Asard, H., Rennenberg, H., Sharkey, T.D., Hansel, A., Schnitzler, J.-P.°: Facing the future effects of short-term climate extremes on isoprene-emitting and non-emitting poplar. Plant Physiol. 169,
560-575 (2015)
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Velikova, V.B., Müller, C., Ghirardo, A., Rock, T., Aichler, M., Walch, A.K., Schmitt-Kopplin, P.,
Schnitzler, J.-P.°: Knocking down of isoprene emission modifies the lipid matrix of thylakoid membranes
and influences the chloroplast ultrastructure in poplar. Plant Physiol. 168, 859-870 (2015)
Vidovic, M.°, Morina, F.°, Milić, S.°, Albert, A.°, Zechmann, B.°, Tosti, T.°, Winkler, J.B.°, Jovanović, S.V.°:
Carbon allocation from source to sink leaf tissue in relation to flavonoid biosynthesis in variegated
Pelargonium zonale under UV-B radiation and high PAR intensity. Plant Physiol. Biochem. 93, 44-55 (2015)
Vogel, C.°, Heister, K., Buegger, F., Tanuwidjaja, I., Haug, S., Schloter, M., Kögel-Knabner, I.: Clay
mineral composition modifies decomposition and sequestration of organic carbon and nitrogen in fine soil
fractions. Biol. Fertil. Soils 51, 427-442 (2015)
Wang, F., Dörfler, U., Jiang, X., Schroll, R.°: Predicting isoproturon long-term mineralization from
short-term experiment: Can this be a suitable approach? Chemosphere 144, 312-318 (2016) [published
online 2015]
Weikl, F.°, Radl, V., Munch, J.-C., Pritsch, K.: Targeting allergenic fungi in agricultural environments aids
the identification of major sources and potential risks for human health. Sci. Total Environ. 529, 223-230
(2015)
Wimmer, M.#, Alessandrini, F.#°, Gilles, S., Frank, U., Oeder, S., Hauser, M., Ring, J., Ferreira, F., Ernst,
D., Winkler, J.B., Schmitt-Kopplin, P., Ohnmacht, C., Behrendt, H., Schmidt-Weber, C.B.,
Traidl-Hoffmann, C., Gutermuth, J.: Pollen-derived adenosine is a necessary co-factor for ragweed allergy.
Allergy 70, 944-954 (2015)
Zeiller, M., Rothballer, M., Iwobi, A., Böhnel, H., Gessler, F., Hartmann, A., Schmid, M.°: Systemic
colonization of clover (Trifolium repens) by Clostridium botulinum strain 2301. Front. Microbiol. 6:1207 (2015)
Zhao, F., El-Kelish, A., Durner, J., Lindermayr, C., Winkler, J.B., Rueff, F., Behrendt, H., Traidl-Hoffmann,
C., Holzinger, A., Kofler, W., Braun, P., von Toerne, C., Hauck, S.M., Ernst, D., Frank, U.°: Common
ragweed (Ambrosia artemisiifolia L.): Allergenicity and molecular characterisation of pollen after plant
exposure to elevated NO2. Plant Cell Environ. 39, 147-164 (2016) [published online 2015]
Zhu, X.M., Kuang, Y.-W.°, Li, J., Schroll, R., Wen, D.Z.: Metals and possible sources of lead in aerosols at
the Dinghushan nature reserve, southern China. Rapid Commun. Mass Spectrom. 29, 1403-1410 (2015)
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Sustainable Water Management
Acharya, S.M.°, Kundu, K., Sreekrishnan, T.R.: Improved stability of anaerobic digestion through the use of
selective acidogenic culture. J. Environ. Eng. 141:04015001 (2015)
Adomako, D., Gibrilla, A.°, Maloszewski, P., Ganyaglo, S.Y., Rai, S.: Tracing stable isotopes (δ2H and δ18O)
from meteoric water to groundwater in the Densu River basin of Ghana. Environ. Monit. Assess. 187:264
(2015)
Audí-Miró, C.°, Cretnik, S., Torrentó, C., Rosell, M., Shouakar-Stash, O., Otero, N., Palau, J., Elsner, M.,
Soler, A.: C, Cl and H compound-specific isotope analysis to assess natural versus Fe(0) barrier-induced
degradation of chlorinated ethenes at a contaminated site. J. Hazard. Mater. 299, 747-754 (2015)
Banoub, J.H., Demian, W.L., Piazzetta, P., Sarkis, G., Kanawati, B., Lafont, D., Laurent, N., Vaillant, C.,
Randell, E., Giorgi, G., Fridgen, T.D.°: The in situ gas-phase formation of a C-glycoside ion obtained during
electrospray ionization tandem mass spectrometry. A unique intramolecular mechanism involving an
ion-molecule reaction. Rapid Commun. Mass Spectrom. 29, 1717-1732 (2015)
Bayer, A., Drexel, R., Weber, N., Griebler, C.°: Quantification of aquatic sediment prokaryotes - a
multiple-steps optimization testing sands from pristine and contaminated aquifers. Limnologica 56, 6-13
(2016) [published online 2015]
Bianco, G., Battista, F., Buchicchio, A., Amarena, C.G., Schmitt-Kopplin, P., Guerrieri, A.°: Structural
characterization of arginine-vasopressin and lysine-vasopressin by Fourier-transform ion cyclotron
resonance mass spectrometry and infrared multiphoton dissociation. Eur. J. Mass Spectrom. 21, 211-219
(2015)
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Bögershausen, N. , Tsai, I.C. , Pohl, E., Kiper, P., Beleggia, F., Percin, E.F., Keupp, K., Matchan, A., Milz,
E., Alanay, Y., Kayserili, H., Liu, Y., Banka, S., Kranz, A., Zenker, M., Wieczorek, D., Elcioğlu, N.H.,
Prontera, P., Lyonnet, S., Meitinger, T., Stewart, A.F., Donnai, D., Strom, T.M., Boduroglu, K., Yigit, G., Li,
Y., Katsanis, N., Wollnik, B.°: RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome. J. Clin.
Invest. 125, 3585-3599 (2015)
Bussian, B.M.°, Pandelova, M., Lehnik-Habrink, P., Aichner, B., Henkelmann, B., Schramm, K.-W.:
Persistent endosulfan sulfate is found with highest abundance among endosulfan I, II, and sulfate in German
forest soils. Environ. Pollut. 206, 661-666 (2015)
Chowdhury, S.P.°, Uhl, J., Grosch, R., Alqueres, S., Pittroff, S., Dietel, K., Schmitt-Kopplin, P., Borriss,
R., Hartmann, A.: Cyclic lipopeptides of Bacillus amyloliquefaciens subsp. plantarum colonizing the lettuce
rhizosphere enhance plant defence responses towards the bottom rot pathogen Rhizoctonia solani. Mol.
Plant Microbe Interact. 28, 984-995 (2015)
Coelho, C.°, Aron, A., Roullier-Gall, C., Gonsior, M., Schmitt-Kopplin, P., Gougeon, R.D.: Fluorescence
fingerprinting of bottled white wines can reveal memories related to sulfur dioxide treatments of the must.
Anal. Chem. 87, 8132-8137 (2015)
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Deyerling, D., Wang, J., Bi, Y., Peng, C., Pfister, G., Henkelmann, B., Schramm, K.-W.: Depth profile of
persistent and emerging organic pollutants upstream of the Three Gorges Dam gathered in 2012/2013.
Environ. Sci. Pollut. Res. 23, 5782-5794 (2016) [published online 2015]
Deyerling, D., Schramm, K.-W.: Integrated targeted and non-targeted analysis of water sample extracts
with micro-scale UHPLC-MS. MethodsX 2, 399-408 (2015)
Down, A., Schreglmann, K., Plata, D.L., Elsner, M., Warner, N.R., Vengosh, A., Moore, K., Coleman, D.,
Jackson, R.B.°: Pre-drilling background groundwater quality in the Deep River Triassic Basin of central North
Carolina, USA. Appl. Geochem. 60, 3–13 (2015)
Drollette, B.D., Hoelzer, K., Warner, N.R., Darrah, T.H., Karatum, O., O'Connor, M.P., Nelson, R.K.,
Fernandez, L.A., Reddy, C.M., Vengosh, A., Jackson, R.B., Elsner, M., Plata, D.L.°: Elevated levels of diesel
range organic compounds in groundwater near Marcellus gas operations are derived from surface activities.
Proc. Natl. Acad. Sci. U.S.A. 112, 13184-13189 (2015)
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Dučić, T. °, Carboni, E. , Lai, B., Chen, S., Michalke, B., Lázaro, D.F., Outeiro, T.F., Bähr, M., Barski, E.,
Lingor, P.°: Alpha-synuclein regulates neuronal levels of manganese and calcium. ACS Chem. Neurosci. 6,
1769-1779 (2015)
Eckert, D., Kürzinger, P., Bauer, R.D., Griebler, C., Cirpka, O.A.°: Fringe-controlled biodegradation under
dynamic conditions: Quasi 2-D flow-through experiments and reactive-transport modeling. J. Contam.
Hydrol. 172, 100-111 (2015)
Einsiedl, F.°, Pilloni, G., Ruth-Anneser, B., Lueders, T., Griebler, C.: Spatial distributions of sulphur
species and sulphate-reducing bacteria provide insights into sulphur redox cycling and biodegradation
hot-spots in a hydrocarbon-contaminated aquifer. Geochim. Cosmochim. Acta 156, 207-221 (2015)
Ellouzi, I., ELayazi, L., Harir, M., Schmitt-Kopplin, P., Laanab, L., Mountacer, H., El Hajjaji, S.°: Synthesis
and characterization of C, N, S and Fe modified TiO2 nanophotocatalysist: Efficiency on the degradation of
Methyl orange and levafix blue. Phys. Chem. News 75, accepted (2015)
Filippini, M.°, Stumpp, C., Nijenhuis, I., Richnow, H.H., Gargini, A.: Evaluation of aquifer recharge and
vulnerability in an alluvial lowland using environmental tracers. J. Hydrol. 529, 1657-1668 (2015)
Forcisi, S.#, Moritz, F.#, Lucio, M., Lehmann, R., Stefan, N., Schmitt-Kopplin, P.°: Solutions for low and
high accuracy mass spectrometric data matching. A data-driven annotation strategy in non-targeted
metabolomics. Anal. Chem. 87, 8917-8924 (2015)
Galvao, P.°, Henkelmann, B., Longo, R., Torres, J.P.M., Malm, O., Schramm, K.-W.: The brown mussel
Perna perna (L., 1758) as a sentinel species for chlorinated pesticide and dioxin-like compounds. Environ.
Sci. Pollut. Res. 22, 13522-13533 (2015)
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Getzinger, G.J., O'Connor, M.P., Hoelzer, K., Drollette, B.D., Karatum, O., Deshusses, M.A., Ferguson, P.L.,
Elsner, M., Plata, D.L.°: Natural gas residual fluids: Sources, endpoints, and organic chemical composition
after centralized waste treatment in Pennsylvania. Environ. Sci. Technol. 49, 8347-8355 (2015)
Gharasoo, M.°, Centler, F., van Cappellen, P., Wick, L.Y., Thullner, M.: Kinetics of substrate biodegradation
under the cumulative effects of bioavailability and self-inhibition. Environ. Sci. Technol. 49, 5529-5537 (2015)
Gonsior, M., Mitchelmore, C., Heyes, A., Harir, M., Richardson, S.D., Petty, W.T., Wright, D.A.,
Schmitt-Kopplin, P.°: Bromination of marine dissolved organic matter following full scale electrochemical
ballast water disinfection. Environ. Sci. Technol. 49, 9048-9055 (2015)
Götz-Rösch, C.#, Sieper, T.#, Fekete, A., Schmitt-Kopplin, P., Hartmann, A., Schröder, P.°: Influence of
bacterial N-acyl-homoserine lactones on growth parameters, pigments, antioxidative capacities and the
xenobiotic phase II detoxification enzymes in barley and yam bean. Front. Plant Sci. 6:205 (2015)
Griebler, C.°, Avramov, M.°: Groundwater ecosystem services: A review. Freshw. Sci. 34, 355-367 (2015)
Gründger, F., Jimenez, N., Thielemann, T., Straaten, N., Lüders, T., Richnow, H.-H., Krüger, M.°: Microbial
methane formation in deep aquifers of a coal-bearing sedimentary basin, Germany. Front. Microbiol. 6:200
(2015)
Guigue, J.°, Lévêque, J., Mathieu, O., Schmitt-Kopplin, P., Nawata, S., Lucio, M., Arrouays, D., Jolivet,
C.C., Dequiedt, S., Chemidlin Prévost-Bouré, N., Ranjard, L.: Water-extractable organic matter linked to soil
physico-chemistry and microbiology at the regional scale. Soil Biol. Biochem. 84, 158-167 (2015)
He, X., Hartlieb, E., Rothmund, L., Waschke, J., Wu, X., van Landuyt, K.L., Milz, S., Michalke, B., Hickel, R.,
Reichl, F.X., Högg, C.H.°: Intracellular uptake and toxicity of three different Titanium particles. Dent. Mater.
31, 734-744 (2015)
Heinzmann, S.S.°, Holmes, E., Kochhar, S., Nicholson, J.K., Schmitt-Kopplin, P.: 2-Furoylglycine as a
candidate biomarker of coffee consumption. J. Agric. Food Chem. 63, 8615-8621 (2015)
Heinzmann, S.S.°, Schmitt-Kopplin, P.: Deep metabotyping of the murine gastrointestinal tract for the
visualization of digestion and microbial metabolism. J. Proteome Res. 14, 2267-2277 (2015)
Hernández, R.B.°, Nishita, M.I., Espósito, B.P., Scholz, S., Michalke, B.: The role of chemical speciation,
chemical fractionation and calcium disruption in manganese-induced developmental toxicity in zebrafish
(Danio rerio) embryos. J. Trace Elem. Med. Biol. 32, 209-217 (2015)
Hertkorn, N., Harir, M., Schmitt-Kopplin, P.: Nontarget analysis of Murchison soluble organic matter by
high-field NMR spectroscopy and FTICR mass spectrometry. Magn. Reson. Chem. 53, 754-768 (2015)
Herzsprung, P.°, von Tümpling, W., Hertkorn, N., Harir, M., Friese, K., Schmitt-Kopplin, P.: High-field
FTICR-MS data evaluation of natural organic matter: Are CHON5S2 molecular class formulas assigned to
13
C isotopic m/z and in reality CHO components? Anal. Chem. 87, 9563-9566 (2015)
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Sustainable Water Management
Höhener, P.°, Elsner, M., Eisenmann, H., Atteia, O.: Improved constraints on in situ rates and on
quantification of complete chloroethene degradation from stable carbon isotope mass balances in
groundwater plumes. J. Contam. Hydrol. 182, 173-182 (2015)
Höss, S.°, Frank-Fahle, B., Lueders, T., Traunspurger, W.: Response of bacteria and meiofauna to iron
oxide colloids in sediments of freshwater microcosms. Environ. Toxicol. Chem. 34, 2660-2669 (2015)
Höss, S.°, Fritzsche, A., Meyer, C., Bosch, J., Meckenstock, R.U., Totsche, K.U.: Size- and
composition-dependent toxicity of synthetic and soil-derived Fe oxide colloids for the nematode
Caenorhabditis elegans. Environ. Sci. Technol. 49, 544-552 (2015)
Humann-Ziehank, E., Ganter, M., Michalke, B.°: Selenium speciation in paired serum and cerebrospinal
fluid samples of sheep. J. Trace Elem. Med. Biol. 33, 14-20 (2016) [published online 2015]
Jeandet, P.°, Heinzmann, S.S., Roullier-Gall, C., Cilindre, C., Aron, A., Deville, M.A., Moritz, F., Karbowiak,
T., Demarville, D., Brun, C., Moreau, F., Michalke, B., Liger-Belair, G., Witting, M., Lucio, M., Steyer, D.,
Gougeon, R.D., Schmitt-Kopplin, P.°: Chemical messages in 170-year-old champagne bottles from the
Baltic Sea: Revealing tastes from the past. Proc. Natl. Acad. Sci. U.S.A. 112, 5893-5898 (2015)
Kamilli, K.A.°, Ofner, J., Lendl, B., Schmitt-Kopplin, P., Held, A.: New particle formation above a simulated
salt lake in aerosol chamber experiments. Environ. Chem. 12, 489-503 (2015)
Kanaparthi, D., Conrad, R.°: Role of humic substances in promoting autotrophic growth in nitrate-dependent
iron-oxidizing bacteria. Syst. Appl. Microbiol. 38, 184-188 (2015)
Keil, K.°, Zucolotto, M.E., Krot, A.N., Doyle, P.M., Telus, M., Krot, T.V., Greenwood, R.C., Franchi, I.A.,
Wasson, J.T., Welten, K.C., Caffee, M.W., Sears, D.W.G., Riebe, M., Wieler, R., dos Santos, E., Scorzelli,
R.B., Gattacceca, J., Lagroix, F., Laubenstein, M., Mendes, J.C., Schmitt-Kopplin, P., Harir, M., Moutinho,
A.L.R.: The Vicência meteorite fall: A new unshocked (S1) weakly metamorphosed (3.2) LL chondrite.
Meteorit. Planet. Sci. 50, 1089-1111 (2015)
Kekišev, O.°, Kaljurand, I., Toom, L., Lenoir, D., Burk, P., Järv, J.: Effect of strain on gas-phase basicity of
(E)-1-methyl-2-(1-methyl-2-adamantylidene)adamantane. J. Phys. Org. Chem. 28, 447-451 (2015)
Klaus, J.°, Chun, K., Stumpp, C.: Temporal trends in δ18O composition of precipitation in Germany: Insights
from time series modelling and trend analysis. Hydrol. Process. 29, 2668-2680 (2015)
Knorr, B., Maloszewski, P., Krämer, F., Stumpp, C.°: Diffusive mass exchange of non-reactive substances
in dual-porosity porous systems - column experiments under saturated conditions. Hydrol. Process. 30,
914-926 (2016) [published online 2015]
Kubryk, P., Kölschbach, J.S., Marozava, S., Lueders, T., Meckenstock, R.U., Niessner, R., Ivleva, N.P.°:
Exploring the potential of stable isotope (resonance) raman microspectroscopy and SERS for the analysis of
microorganisms at single cell level. Anal. Chem. 87, 6622-6630 (2015)
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Kurmayer, R. °, Blom, J.F. , Deng, L. , Pernthaler, J.: Integrating phylogeny, geographic niche partitioning
and secondary metabolite synthesis in bloom-forming Planktothrix. ISME J. 9, 909-921 (2015)
Labella, C., Kanawati, B., Vogel, H., Schmitt-Kopplin, P., Laurino, S., Bianco, G.°, Falabella, P.°:
Identification of two arginine kinase forms of endoparasitoid Leptomastix dactylopii venom by bottom
up-sequence tag approach. J. Mass Spectrom. 50, 756-765 (2015)
Lagkouvardos, I., Kläring, K., Heinzmann, S.S., Platz, S., Scholz, B.A., Engel, K.H., Schmitt-Kopplin, P.,
Haller, D., Rohn, S., Skurk, T., Clavel, T.°: Gut metabolites and bacterial community networks during a pilot
intervention study with flaxseeds in healthy adult men. Mol. Nutr. Food Res. 59, 1614–1628 (2015)
Lavonen, E.E.°, Kothawala, D.N., Tranvik, L.J., Gonsior, M., Schmitt-Kopplin, P., Kohler, S.J.: Tracking
changes in the optical properties and molecular composition of dissolved organic matter during drinking
water production. Water Res. 85, 286-294 (2015)
Lechtenfeld, O.J.°, Hertkorn, N., Shen, Y., Witt, M., Benner, R.°: Marine sequestration of carbon in bacterial
metabolites. Nat. Commun. 6:6711 (2015)
Liu, Y., Rousseaux, S., Tourdot-Maréchal, R., Sadoudi, M., Gougeon, R., Schmitt-Kopplin, P., Alexandre,
H.°: Wine microbiome, a dynamic world of microbial interactions. Crit. Rev. Food Sci. Nutr., DOI:
10.1080/10408398.2014.983591 (2015)
Lou, Z., Bilitewski, B., Zhu, N., Chai, X., Li, B.Q., Zhao, Y.°, Otieno, P.O.: Greenhouse gas emission and its
potential mitigation process from the waste sector in a large-scale exhibition. J. Environ. Sci. 31, 44-50
(2015)
Lundberg, A.°, Ala-Aho, P., Eklo, O.-M., Klöve, B., Kværner, J., Stumpp, C.: Snow and frost: Implications for
spatiotemporal infiltration patterns - a review. Hydrol. Process. 30, 1230-1250 (2016) [published online 2015]
Lyubenova, L.°, Sabodash, X., Schröder, P., Michalke, B.: Selenium species in the roots and shoots of
chickpea plants treated with different concentrations of sodium selenite. Environ. Sci. Pollut. Res. 22,
16978-16986 (2015)
Meckenstock, R.U., Elsner, M., Griebler, C., Lueders, T., Stumpp, C., Dejonghe, W., Bastiaens, L.L.,
Springael, D., Smolders, E., Boon, N., Agathos, S.N., Sorensen, S.R., Aamand, J., Albrechtsen, H.J., Bjerg,
P.L., Schmidt, S., Huang, W.E., van Breukelen, B.M.: Biodegradation: Updating the concepts of control for
microbial clean-up in contaminated aquifers. Environ. Sci. Technol. 49, 7073-7081 (2015)
Mellage, A., Eckert, D., Grösbacher, M., Inan, A.Z., Cirpka, O.A.°, Griebler, C.: Dynamics of suspended
and attached aerobic toluene degraders in small-scale flow-through sediment systems under growth and
starvation conditions. Environ. Sci. Technol. 49, 7161-7169 (2015)
Mertes, F., Lichtner, B., Kuhl, H., Blattner, M., Otte, J., Wruck, W., Timmermann, B., Lehrach, H., Adjaye, J.:
Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells. BMC
Genomics 16:925 (2015)
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Michalke, B.°, Aslanoglou, L., Ochsenkühn-Petropoulou, M., Bergström, B., Berthele, A., Vinceti, M.,
Lucio, M., Lidén, G.: An approach for manganese biomonitoring using a manganese carrier switch in serum
from transferrin to citrate at slightly elevated manganese concentration. J. Trace Elem. Med. Biol. 32,
145-154 (2015)
Mindl, B., Hofer, J., Kellermann, C.S., Stichler, W., Teichmann, G., Psenner, R., Danielopol, D.L.,
Neudorfer, W., Griebler, C.°: Evaluating the performance of water purification in a vegetated groundwater
recharge basin maintained by short-term pulsed infiltration events. Water Sci. Technol. 72, 1912-1922 (2015)
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Mogusu, E.O., Wolbert, J.B., Kujawinski, D.M., Jochmann, M.A., Elsner, M.°: Dual element ( N/ N, C/
12
C) isotope analysis of glyphosate and AMPA by derivatization-gas chromatography isotope ratio mass
spectrometry (GC/IRMS) combined with LC/IRMS. Anal. Bioanal. Chem. 407, 5249-5260 (2015)
Moritz, F.°, Janicka, M., Zygler, A., Forcisi, S., Kot-Wasik, A., Kot, J., Gebefügi, I.L., Namiesnik, J.,
Schmitt-Kopplin, P.°: The compositional space of exhaled breath condensate and its link to the human
breath volatilome. J. Breath Res. 9:027105 (2015)
Müller, A., Kaling, M., Faubert, P., Gort, G., Smid, H.M., van Loon, J.J., Dicke, M., Kanawati, B.,
Schmitt-Kopplin, P., Polle, A., Schnitzler, J.-P., Rosenkranz, M.°: Isoprene emission by poplar is not
important for the feeding behaviour of poplar leaf beetles. BMC Plant Biol. 15:165 (2015)
Müller, L., Jakobi, G., Czech, H., Stengel, B., Orasche, J., Arteaga-Salas, J.M., Karg, E.W., Elsasser, M.,
Sippula, O., Streibel, T., Slowik, J.G., Prevot, A.S.H., Jokiniemi, J., Rabe, R., Harndorf, H., Michalke, B.,
Schnelle-Kreis, J.°, Zimmermann, R.°: Characteristics and temporal evolution of particulate emissions from
a ship diesel engine. Appl. Energy 155, 204-217 (2015)
Neth, K.°, Lucio, M., Walker, A., Zorn, J., Schmitt-Kopplin, P., Michalke, B.: Changes in brain
metallome/metabolome pattern due to a single i.v. injection of manganese in rats. PLoS ONE 10:e0138270
(2015)
Neth, K.°, Lucio, M., Walker, A., Kanawati, B., Zorn, J., Schmitt-Kopplin, P., Michalke, B.: Diverse
serum manganese species affect brain metabolites depending on exposure conditions. Chem. Res. Toxicol.
28, 1434-1442 (2015)
Nghi, D.H.°, Ullrich, R., Moritz, F., Huong, L.M.A., Giap, V.D., Chi, D., Hofrichter, M., Liers, C.: The
ascomycete Xylaria polymorpha produces an acetyl esterase that solubilises beech wood material to release
water-soluble lignin fragments. J. Korean Soc. Appl. Biol. Chem. 58, 415-421 (2015)
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Oeder, S. , Kanashova, T. , Sippula, O. , Sapcariu, S.C. , Streibel, T. , Arteaga-Salas, J.M. , Passig, J. ,
Dilger, M., Paur, H.R., Schläger, C., Mülhopt, S., Diabaté, S., Weiss, C., Stengel, B., Rabe, R., Harndorf, H.,
Torvela, T., Jokiniemi, J.K., Hirvonen, M.R., Schmidt-Weber, C.B., Traidl-Hoffmann, C., BéruBé, K.A.,
Wlodarczyk, A.J., Prytherch, Z., Michalke, B., Krebs, T., Prévôt, A.S., Kelbg, M., Tiggesbäumker, J., Karg,
E.W., Jakobi, G., Scholtes, S., Schnelle-Kreis, J., Lintelmann, J., Matuschek, G., Sklorz, M., Klingbeil,
S., Orasche, J., Richthammer, P., Müller, L., Elsasser, M., Reda, A., Gröger, T.M., Weggler, B.A.,
Schwemer, T., Czech, H., Rüger, C.P., Abbaszade, G., Radischat, C., Hiller, K., Buters, J.T.M., Dittmar, G.,
Zimmermann, R.°: Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show
strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions. PLoS
ONE 10:e0126536 (2015)
Ongeri, D.M.K., Lalah, J.O.°, Michalke, B., Schramm, K.-W.: Speciation study of trace elements in surface
sediment of Winam Gulf, Lake Victoria, by sequential extraction, aqua-regia acid digestion, and ICP-OES.
Toxicol. Environ. Chem. 96, 1489-1500 (2015)
Peng, S., Liu, L., Zhang, X., Heinrich, J., Zhang, J., Schramm, K.-W., Huang, Q., Tian, M., Eqani, S.A.,
Shen, H.°: A nested case-control study indicating heavy metal residues in meconium associate with maternal
gestational diabetes mellitus risk. Environ. Health 14:19 (2015)
Pfannes, K.R., Langenbach, K.M., Pilloni, G., Stührmann, T., Euringer, K., Lueders, T., Neu, T.R., Müller,
J.A.°, Kästner, M., Meckenstock, R.U.: Selective elimination of bacterial faecal indicators in the
Schmutzdecke of slow sand filtration columns. Appl. Microbiol. Biotechnol. 99, 10323-10332 (2015)
Roullier-Gall, C., Witting, M., Tziotis, D., Ruf, A., Gougeon, R.°, Schmitt-Kopplin, P.°: Integrating
analytical resolutions in non-targeted wine metabolomics. Tetrahedron 71, 2983-2990 (2015)
Rühle, F., von Netzer, F., Lueders, T., Stumpp, C.°: Response of transport parameters and sediment
microbiota to water table fluctuations in laboratory columns. Vadose Zone J. 14, DOI:
10.2136/vzj2014.09.0116 (2015)
Sampsonidis, I., Witting, M., Koch, W., Virgiliou, C., Gika, H.G., Schmitt-Kopplin, P., Theodoridis, G.A.°:
Computational analysis and ratiometric comparison approaches aimed to assist column selection in
hydrophilic interaction liquid chromatography-tandem mass spectrometry targeted metabolomics. J.
Chromatogr. A 1406, 145-155 (2015)
Schürner, H.K.V., Seffernick, J.L., Grzybkowska, A., Dybała-Defratyka, A., Wackett, L.P., Elsner, M.°:
Characteristic isotope fractionation patterns in s-triazine degradation have their origin in multiple protonation
options in the s-triazine hydrolase trzn. Environ. Sci. Technol. 49, 3490-3498 (2015)
Stoewer, M., Knöller, K., Stumpp, C.°: Tracing freshwater nitrate sources in pre-alpine groundwater
catchments using environmental tracers. J. Hydrol. 524, 753-767 (2015)
Temoka, C.°, Wang, J., Bi, Y., Deyerling, D., Pfister, G., Henkelmann, B., Schramm, K.-W.°:
Concentrations and mass fluxes estimation of organochlorine pesticides in Three Gorges Reservoir with
virtual organisms using in situ PRC-based sampling rate. Chemosphere 144, 1521-1529 (2015)
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Sustainable Water Management
Teumer, A., Tin, A., Sorice, R., Gorski, M., Yeo, N.C., Chu, A.Y., Li, M., Li, Y., Mijatovic, V., Ko, Y.A., Taliun,
D., Luciani, A., Chen, M.H., Yang, Q., Foster, M.C., Olden, M., Hiraki, L.T., Tayo, B.O., Fuchsberger, C.,
Dieffenbach, A.K., Shuldiner, A.R., Smith, A.V., Zappa, A.M., Lupo, A., Kollerits, B., Ponte, B., Stengel, B.,
Krämer, B.K., Paulweber, B., Mitchell, B.D., Hayward, C., Helmer, C., Meisinger, C., Gieger, C., Shaffer,
C.M., Müller, C., Langenberg, C., Ackermann, D., Siscovick, D., Boerwinkle, E.E., Kronenberg, F., Ehret,
G.B., Homuth, G., Waeber, G., Navis, G., Gambaro, G., Malerba, G., Eiriksdottir, G., Li, G., Wichmann,
H.-E., Grallert, H., Wallaschofski, H., Völzke, H., Brenner, H., Kramer, H., Leach, I.M., Rudan, I., Hillege,
J.L., Beckmann, J.S., Lambert, J.C., Luan, J., Zhao, J.H., Chalmers, J., Coresh, J., Denny, J.C., Butterbach,
K., Launer, L.J., Ferrucci, L., Kedenko, L., Haun, M., Metzger, M., Woodward, M., Hoffman, M.J., Nauck, M.,
Waldenberger, M., Pruijm, M., Bochud, M., Rheinberger, M., Verweij, N., Wareham, N.J., Endlich, N.,
Soranzo, N., Polasek, O., van der Harst, P., Pramstaller, P.P., Vollenweider, P., Wild, P.S., Gansevoort,
R.T., Rettig, R., Biffar, R., Carroll, R.J., Katz, R., Loos, R.J., Hwang, S.J., Coassin, S., Bergmann, S., Rosas,
S.E., Stracke, S., Harris, T.B., Corre, T., Zeller, T., Illig, T., Aspelund, T., Tanaka, T., Lendeckel, U., Völker,
U., Gudnason, V., Chouraki, V., Koenig, W., Kutalik, Z., O'Connell, J.R., Parsa, A., Heid, I.M., Paterson,
A.D., de Boer, I.H., Devuyst, O., Lazar, J., Endlich, K., Susztak, K., Tremblay, J., Hamet, P., Jacob, H.J.,
Böger, C.A., Fox, C.S., Pattaro, C., Köttgen, A.: Genome-wide association studies identify genetic loci
associated with albuminuria in diabetes. Diabetes 65, 803-817 (2016) [published online 2015]
Tohge, T., Zhang, Y., Peterek, S., Matros, A., Rallapalli, G., Tandrón, Y.A., Butelli, E., Kallam, K., Hertkorn,
N., Mock, H.P., Martin, C., Fernie, A.R.°: Ectopic expression of snapdragon transcription factors facilitates
the identification of genes encoding enzymes of anthocyanin decoration in tomato. Plant J. 83, 686-704
(2015)
Träber, S.C.°, Li, W.B.°, Höllriegl, V., Nebelung, K., Michalke, B., Rühm, W., Oeh, U.: Calculation of
internal dose from ingested soil-derived uranium in humans: Application of a new method. Radiat. Environ.
Biophys. 54, 265-272 (2015)
Ulutas, O.K.°, Cok, I., Darendeliler, F., Aydin, B., Coban, A., Henkelmann, B., Schramm, K.-W.: Blood
concentrations and risk assessment of persistent organochlorine compounds in newborn boys in Turkey. A
pilot study. Environ. Sci. Pollut. Res. 22, 19896-19904 (2015)
Ulutas, O.K.°, Cok, I., Darendeliler, F., Aydin, B., Coban, A., Henkelmann, B., Schramm, K.-W.: Blood
levels of polychlorinated biphenlys and organochlorinated pesticides in women from Istanbul, Turkey.
Environ. Monit. Assess. 187:132 (2015)
Velikova, V.B., Müller, C., Ghirardo, A., Rock, T., Aichler, M., Walch, A.K., Schmitt-Kopplin, P.,
Schnitzler, J.-P.°: Knocking down of isoprene emission modifies the lipid matrix of thylakoid membranes
and influences the chloroplast ultrastructure in poplar. Plant Physiol. 168, 859-870 (2015)
Vinceti, M.°, Grill, P., Malagoli, C., Filippini, T., Storani, S., Malavolti, M., Michalke, B.°: Selenium speciation
in human serum and its implications for epidemiologic research: A cross-sectional study. J. Trace Elem.
Med. Biol. 31, 1-10 (2015)
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Sustainable Water Management
Wang, J.°, Liang, W., Henkelmann, B., Pfister, G., Schramm, K.-W.°: Organochlorine pesticides
accumulated by SPMD-based virtual organisms and feral fish in Three Gorges Reservoir, China. Environ.
Pollut. 202, 160-167 (2015)
Wang, J., Bi, Y., Henkelmann, B., Pfister, G., Zhang, L., Schramm, K.-W.: PAHs and PCBs accumulated
by SPMD-based virtual organisms and feral fish in Three Gorges Reservoir, China. Sci. Total Environ. 542,
899-907 (2016) [published online 2015]
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Wimmer, M. , Alessandrini, F. °, Gilles, S., Frank, U., Oeder, S., Hauser, M., Ring, J., Ferreira, F., Ernst,
D., Winkler, J.B., Schmitt-Kopplin, P., Ohnmacht, C., Behrendt, H., Schmidt-Weber, C.B.,
Traidl-Hoffmann, C., Gutermuth, J.: Pollen-derived adenosine is a necessary co-factor for ragweed allergy.
Allergy 70, 944-954 (2015)
Witting, M.°, Rudloff, H., Thondamal, M., Aguilaniu, H., Schmitt-Kopplin, P.: Fast separation and
quantification of steroid hormones ∆4- and ∆7-dafachronic acid in Caenorhabditis elegans. J. Chromatogr. B
978-979, 118-121 (2014)
Witting, M.°, Schmitt-Kopplin, P.: The Caenorhabditis elegans lipidome A primer for lipid analysis in
Caenorhabditis elegans. Arch. Biochem. Biophys. 589, 27-37 (2015)
Yakimov, M.M.°, la Cono, V.L., Spada, G.L., Bortoluzzi, G., Messina, E., Smedile, F., Arcadi, E., Borghini,
M., Ferrer, M., Schmitt-Kopplin, P., Hertkorn, N., Cray, J.A., Hallsworth, J.E., Golyshin, P.N., Giuliano, L.:
Microbial community of the deep-sea brine Lake Kryos seawater-brine interface is active below the
chaotropicity limit of life as revealed by recovery of mRNA. Environ. Microbiol. 17, 364-382 (2015)
Zhang, L., Jungblut, A.D.°, Hawes, I., Andersen, D.T., Sumner, D.Y., Mackey, T.J.: Cyanobacterial diversity
in benthic mats of the McMurdo Dry Valley lakes, Antarctica. Polar Biol. 38, 1097-1110 (2015)
Zhu, N., Schramm, K.-W., Wang, T., Henkelmann, B., Fu, J., Gao, Y., Wang, Y.°, Jiang, G.: Lichen, moss
and soil in resolving the occurrence of semi-volatile organic compounds on the southeastern Tibetan
Plateau, China. Sci. Total Environ. 518-519, 328-336 (2015)
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Terrestrial Systems – from Observation to Prediction
Asseng, S.°, Ewert, F., Martre, P., Rötter, R.P., Lobell, D.B., Cammarano, D., Kimball, A., Ottmann, M.J.,
Wall, G.W., White, J.W., Reynolds, M.P., Aldermann, P.D., Prasad, P.V.V., Aggarwal, P.K., Anothai, J.,
Basso, B., Biernath, C.J., Challinor, A.J., de Sanctis, G., Doltra, J., Fereres, E., Garcia-Vila, M., Gayler, S.,
Hoogenboom, G., Hunt, L.A., Izaurralde, R.C., Jabloun, M., Jones, C.D., Kersebaum, K.C., Koehler, A.-K.,
Müller, C., Naresh Kumar, S., Nendel, C., O'Leary, G., Olesen, J.E., Palosuo, T., Priesack, E., Eyshi Rezaei,
E., Ruane, A.C., Semenov, M.A., Shcherbak, I., Stöckle, C., Stratonovitch, P., Streck,T., Supit, I., Tao, F.,
Thorburn, P.J., Waha, K., Wang, E., Wallach, D., Wolf, J., Zhao, Z., Zhu, Y.: Rising temperatures reduce
global wheat production. Nat. Clim. Chang. 5, 143-147 (2015)
Hentschel, R.#°, Hommel, R.#, Poschenrieder, W., Grote, R., Holst, J., Biernath, C.J., Gessler, A.,
Priesack, E.: Stomatal conductance and intrinsic water use efficiency in the drought year 2003: A case study
of European beech. Trees-Struct. Funct. 30, 153-174 (2016) [published online 2015]
Makowski, D., Asseng, S., Ewert, F., Bassu, S., Durand, J.L., Li, T., Martre, P., Adam, M., Aggarwal, P.K.,
Angulo, C., Baron, C., Basso, B., Bertuzzi, P., Biernath, C.J., Boogaard, H., Boote, K.J., Bouman, B.,
Bregaglio, S., Brisson, N., Buis, S., Cammarano, D., Challinor, A.J., Confalonieri, R., Conijn, J.G., Corbeels,
M., Deryng, D., de Sanctis, G., Doltra, J., Fumoto, T., Gaydon, D., Gayler, S., Goldberg, R., Grant, R.F.,
Grassini, P., Hatfield, J.L., Hasegawa, T., Heng, L., Hoek, S., Hooker, J., Hunt, L.A., Ingwersen, J.,
Izaurralde, R.C., Jongschaap, R.E.E., Jones, J.W., Kemanian, R.A., Kersebaum, K.C., Kim, S.H., Lizaso, J.,
Marcaida, M., Müller, C., Nakagawa, H., Naresh Kumar, S., Nendel, C., O'Leary, G.J., Olesen, J.E., Oriol, P.,
Osborne, T.M., Palosuo, T., Pravia, M.V., Priesack, E., Ripoche, D., Rosenzweig, C., Ruane, A.C., Ruget,
F., Sau, F., Semenov, M.A., Shcherbak, I., Singh, B., Singh, U., Soo, H.K., Steduto, P., Stöckle, C.,
Stratonovitch, P., Streck, T., Supit, I., Tang, L., Tao, F., Teixeira, E.I., Thorburn, P.J., Timlin, D., Travasso,
M., Rötter, R.P., Waha, K., Wallach, D., White, J.W., Wilkens, P., Williams, J.R., Wolf, J., Yin, X., Yoshida,
H.: A statistical analysis of three ensembles of crop model responses to temperature and CO2 concentration.
Agric. For. Meteorol. 214-215, 483-493 (2015)
Martre, P.°, Wallach, D., Asseng, S., Ewert, F., Jones, J.W., Rötter, R.P., Boote, K.J., Ruane, A.C.,
Thorburn, P.J., Cammarano, D., Hatfield, J.L., Rosenzweig, C., Aggarwal, P.K., Angulo, C., Basso, B.,
Bertuzzi, P., Biernath, C.J., Brisson, N., Challinor, A.J., Doltra, J., Gayler, S., Goldberg, R., Grant, R.F.,
Heng, L., Hooker, J., Hunt, L.A., Ingwersen, J., Izaurralde, R.C., Kersebaum, K.C., Müller, C., Kumar, S.N.,
Nendel, C., O'Leary, G., Olesen, J.E., Osborne, T.M., Palosuo, T., Priesack, E., Ripoche, D., Semenov,
M.A., Shcherbak, I., Steduto, P., Stöckle, C.O., Stratonovitch, P., Streck, T., Supit, I., Tao, F., Travasso, M.,
Waha, K., White, J.W., Wolf, J.: Multimodel ensembles of wheat growth: Many models are better than one.
Glob. Change Biol. 21, 911-925 (2015)
Parker, P.°, Ingwersen, J., Högy, P., Priesack, E., Aurbacher, J.: Simulating regional climate-adaptive field
cropping with fuzzy logic management rules and genetic advance. J. Agric. Sci. 154, 207-222 (2015)
Qu, W.°, Bogena, H.R., Huisman, J.A.H., Vanderborght, J.P., Schuh, M., Priesack, E., Vereecken, H.:
Predicting subgrid variability of soil water content from basic soil information. Geophys. Res. Lett. 42,
789-796 (2015)
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Terrestrial Systems – from Observation to Prediction
Wang, L., Aasly, J.O., Annesi, G., Bardien, S., Bozi, M., Brice, A., Carr, J.J., Chung, S.J., Clarke, C.,
Crosiers, D., Deutschländer, A., Eckstein, G.N., Farrer, M.J., Goldwurm, S., Garraux, G., Hadjigeorgiou,
G.M., Hicks, A.A., Hattori, N., Klein, C., Jeon, B., Kim, Y.J., Lesage, S., Lin, J.J., Lynch, T., Lichtner, P.,
Lang, A.E., Mok, V., Jasinska-Myga, B., Mellick, G.D., Morrison, K.E., Opala, G., Pihlstrom, L., Pramstaller,
P.P., Park, S.S., Quattrone, A., Rogaeva, E., Ross, O.A., Stefanis, L., Stockton, J.D., Silburn, P.A., Theuns,
J., Tan, E.K., Tomiyama, H., Toft, M.F., van Broeckhoven, C., Uitti, R.J., Wirdefeldt, K., Wszolek, Z.,
Xiromerisiou, G., Yueh, K.C., Zhao, Y., Gasser, T., Maraganore, D.M., Kruger, R., Sharma, M.°: Large-scale
assessment of polyglutamine repeat expansions in Parkinson disease. Neurology 85, 1283-1292 (2015)
Wortmann, S.B.°, Zietkiewicz, S., Kousi, M., Szklarczyk, R., Haack, T.B., Gersting, S.W., Muntau, A.C.,
Rakovic, A., Renkema, G.H., Rodenburg, R.J., Strom, T.M., Meitinger, T., Rubio-Gozalbo, M.E., Chrusciel,
E., Distelmaier, F., Golzio, C., Jansen, J.H., van Karnebeek, C., Lillquist, Y., Lücke, T., Ounap, K., Zordania,
R., Yaplito-Lee, J., van Bokhoven, H., Spelbrink, J.N., Vaz, F.M., Pras-Raves, M., Ploski, R., Pronicka, E.,
Klein, C., Willemsen, M.A., de Brouwer, A.P., Prokisch, H., Katsanis, N., Wevers, R.A.: CLPB mutations
cause 3-methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia,
cataracts, movement disorder. Am. J. Hum. Genet. 96, 245-257 (2015)
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Systemic Analysis of Genetic and Environmental Factors that Impact Health
Abdelaziz, A.°, Sushko, Y., Novotarskyi, S., Koerner, R., Brandmaier, S., Tetko, I.V.: Using online tool
(iPrior) for modeling ToxCast™ assays towards prioritization of animal toxicity testing. Comb. Chem. High
Throughput Screen. 18, 420-438 (2015)
Ahting, U., Mayr, J.A., Vanlander, A.V.I., Hardy, S.A., Santra, S., Makowski, C.C., Alston, C.L., Zimmermann,
F.A., Abela, L., Plecko, B.R., Rohrbach, M.A., Spranger, S., Seneca, S.H., Rolinski, B., Hagendorff, A.,
Hempel, M.S., Sperl, W.J.K., Meitinger, T., Smet, J.E., Taylor, R.W., van Coster, R.N.A., Freisinger, P.,
Prokisch, H., Haack, T.B.°: Clinical, biochemical, and genetic spectrum of seven new patients with NFU1
deficiency. Front. Genet. 6:123 (2015)
Albarqouni, L., von Eisenhart Rothe, A., Ronel, J., Meinertz, T., Ladwig, K.-H.°: Frequency and
covariates of fear of death during myocardial infarction and its impact on prehospital delay: Findings from the
multicentre MEDEA study. Clin. Res. Cardiol. 105, 135-144 (2016) [published online 2015]
Altevers, J., Lukaschek, K., Baumert, J.J., Kruse, J., Meisinger, C., Emeny, R.T., Ladwig, K.-H.°: Poor
structural social support is associated with an increased risk of Type 2 diabetes mellitus: Findings from the
MONICA/KORA Augsburg cohort study. Diabet. Med. 33, 47-54 (2016) [published online 2015]
Amann, U., Kirchberger, I., Heier, M., von Scheidt, W., Kuch, B., Peters, A., Meisinger, C.°: Acute
myocardial infarction in the elderly: Treatment strategies and 28-day-case fatality from the MONICA/KORA
myocardial infarction registry. Cathet. Cardiovasc. Intervent. 87, 680-688 (2016) [published online 2015]
Anton, G.°, Wilson, R.K., Yu, Z., Prehn, C., Zukunft, S., Adamski, J., Heier, M., Meisinger, C.,
Römisch-Margl, W., Wang-Sattler, R., Hveem, K., Wolfenbuttel, B.H.R., Peters, A., Kastenmüller, G.,
Waldenberger, M.: Pre-analytical sample quality: Metabolite ratios as an intrinsic marker for prolonged room
temperature exposure of serum samples. PLoS ONE 10:e0121495 (2015)
Arloth, J., Bogdan, R., Weber, P., Frishman, G., Menke, A., Wagner, K.V., Balsevich, G., Schmidt, M.V.,
Karbalai, N., Czamara, D., Altmann, A., Trümbach, D., Wurst, W., Mehta, D., Uhr, M., Klengel, T., Erhardt,
A., Carey, C.E., Conley, E.D., Ruepp, A., Müller-Myhsok, B., Hariri, A.R., Binder, E.B.°: Genetic differences
in the immediate transcriptome response to stress predict risk-related brain function and psychiatric
disorders. Neuron 86, 1189-1202 (2015)
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Systemic Analysis of Genetic and Environmental Factors that Impact Health
Artigas, M.S., Wain, L.V., Miller, S., Kheirallah, A.K., Huffman, J.E., Ntalla, I., Shrine, N., Obeidat, M.,
Trochet, H., McArdle, W.L., Alves, A.C., Hui, J., Zhao, J.H., Joshi, P.K., Teumer, A., Albrecht, E., Imboden,
M., Rawal, R., Lopez, L.M., Marten, J., Enroth, S., Surakka, I., Polasek, O., Lyytikäinen, L.P., Granell, R.,
Hysi, P.G., Flexeder, C., Mahajan, A., Beilby, J., Bossé, Y., Brandsma, C.A., Campbell, H., Gieger, C.,
Gläser, S., Gonzalez, J.R., Grallert, H., Hammond, C.J., Harris, S.E., Hartikainen, A.L., Heliövaara, M.,
Henderson, J., Hocking, L.J., Horikoshi, M., Hutri-Kähönen, N., Ingelsson, E., Johansson, Å, Kemp, J.P.,
Kolcic, I., Kumar, A., Lind, L., Melén, E., Musk, A.W., Navarro, P., Nickle, D.C., Padmanabhan, S., Raitakari,
O.T., Ried, J.S., Ripatti, S., Schulz, H., Scott, R.A., Sin, D.D., Starr, J.M., Viñuela, A., Völzke, H., Wild, S.H.,
Wright, A.F., Zemunik, T., Jarvis, D.L., Spector, T.D., Evans, D.M., Lehtimäki, T., Kähönen, M., Gyllensten,
U., Rudan, I., Deary, I.J., Karrasch, S., Probst-Hensch, N.M., Heinrich, J., Stubbe, B., Wilson, J.F.,
Wareham, N.J., James, A.L., Morris, A.P., Jarvelin, M.R., Hayward, C., Sayers, I., Hall, I.P., Tobin, M.D.:
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation.
6:8658 (2015)
Asl, H.F., Talukdar, H.A., Kindt, A.S.D., Jain, R.K., Ermel, R., Ruusalepp, A., Nguyen, K.H., Dobrin, R.,
Reilly, D.F., Schunkert, H., Samani, N.J., Braenne, I., Erdmann, J., Melander, O., Qi, J., Ivert, T., Skogsberg,
J., Schadt, E.E., Michoel, T., Bjorkegren, J.L.M.°, CARDIoGRAM Consortium (Döring, A., Meisinger, C.,
Meitinger, T., Peters, A., Wichmann, H.-E.): Expression quantitative trait loci acting across multiple tissues
are enriched in inherited risk for coronary artery disease. Circ. Cardiovasc. Genet. 8, 305-315 (2015)
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Aumann, N. °, Baumeister, S.E. , Rettig, R., Lieb, W., Werner, A., Döring, A., Peters, A., Koenig, W.,
Hannemann, A., Wallaschofski, H., Nauck, M., Stracke, S., Völzke, H., Meisinger, C.: Regional variation of
chronic kidney disease in Germany: Results from two population-based surveys. Kidney Blood Press. Res.
40, 231-243 (2015)
Baertling, F., Haack, T.B., Rodenburg, R.J., Schaper, J., Seibt, A., Strom, T.M., Meitinger, T., Mayatepek,
E., Hadzik, B., Selcan, G., Prokisch, H.°, Distelmaier, F.°: MRPS22 mutation causes fatal neonatal lactic
acidosis with brain and heart abnormalities. Neurogenetics 16, 237-240 (2015)
Bamberg, F.°, Kauczor, H.U., Weckbach, S., Schlett, C.L., Forsting, M., Ladd, S.C., Greiser, K.H., Weber,
M.A., Schulz-Menger, J., Niendorf, T., Pischon, T., Caspers, S., Amunts, K., Berger, K., Bülow, R., Hosten,
N., Hegenscheid, K., Kröncke, T., Linseisen, J., Günther, M., Hirsch, J.G., Köhn, A., Hendel, T., Wichmann,
H.-E., Schmidt, B., Jockel, K.H., Hoffmann, W., Kaaks, R., Reiser, M.F., Völzke, H.: Whole-body MR imaging
in the German National Cohort: Rationale, design, and technical background. Radiology 277, 206-220 (2015)
Bartel, J.#, Krumsiek, J.#, Schramm, K., Adamski, J., Gieger, C., Herder, C., Carstensen, M., Peters, A.,
Rathmann, W., Roden, M., Strauch, K., Suhre, K., Kastenmüller, G., Prokisch, H., Theis, F.J.°: The
human blood metabolome-transcriptome interface. PLoS Genet. 11:e1005274 (2015)
page 21 of 213
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° corresponding authors
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Baumert, J.J. , Huang, J. , McKnight, B. , Sabater-Lleal, M. , Steri, M. , Chu, A.Y., Trompet, S., Lopez,
L.M., Fornage, M., Teumer, A., Tang, W., Rudnicka, A.R., Mälarstig, A., Hottenga, J.J., Kavousi, M., Lahti, J.,
Tanaka, T., Hayward, C., Huffman, J.E., Morange, P.E., Rose, L.M., Basu, S., Rumley, A., Stott, D.J.,
Buckley, B.M., de Craen, A.J., Sanna, S., Masala, M., Biffar, R., Homuth, G., Silveira, A., Sennblad, B., Goel,
A., Watkins, H., Müller-Nurasyid, M., Rückerl, R., Taylor, K., Chen, M., de Geus, E.J., Hofman, A.,
Witteman, J.C., de Maat, M.P.M., Palotie, A., Davies, G., Siscovick, D.S., Kolcic, I., Wild, S.H., Song, J.,
McArdle, W.L., Ford, I., Sattar, N., Schlessinger, D., Grotevendt, A., Franzosi, M.G., Illig, T., Waldenberger,
M., Lumley, T., Tofler, G.H., Willemsen, G., Uitterlinden, A.G., Rivadeneira, F., Räikkönen, K., Chasman,
D.I., Folsom, A.R., Lowe, G.D., Westendorp, R.G., Slagboom, P.E., Cucca, F., Wallaschofski, H.,
Strawbridge, R.J., Seedorf, U., Koenig, W., Bis, J.C., Mukamal, K.J., van Dongen, J., Widen, E., Franco,
O.H., Starr, J.M., Liu, K., Ferrucci, L., Polasek, O., Wilson, J.F., Oudot-Mellakh, T., Campbell, H., Navarro,
P., Bandinelli, S., Eriksson, J., Boomsma, D.I., Dehghan, A., Clarke, R., Hamsten, A., Boerwinkle, E.,
Jukema, J.W., Naitza, S., Ridker, P.M., Völzke, H., Deary, I.J., Reiner, A.P., Tregouet, D., O'Donnell, C.J.,
Strachan, D.P., Peters, A.°, Smith, N.L.°: No evidence for genome-wide interactions on plasma fibrinogen by
smoking, alcohol consumption and body mass index: Results from meta-analyses of 80,607 subjects. PLoS
ONE 9:e111156 (2014)
Baurecht, H.#, Hotze, M.#, Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E.,
Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A.D., Kabesch, M.,
Lee, Y.A., Lieb, W., Marenholz, I., McLean, W.H., Morris, D.W., Mrowietz, U., Nair, R.P., Nöthen, M.M.,
Novak, N., O'Regan, G.M., Schreiber, S., Smith, C., Strauch, K., Stuart, P.E., Trembath, R., Tsoi, L.C.,
Weichenthal, M., Barker, J., Elder, J.T., Weidinger, S.°, Cordell, H.J., Brown, S.J.°: Genome-wide
comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. Am.
J. Hum. Genet. 96, 104-120 (2015)
#
#
Becker, L. , Kling, E. , Schiller, E., Zeh, R., Schrewe, A., Hölter, S.M., Mossbrugger, I., Calzada-Wack,
J., Strecker, V., Wittig, I., Dumitru, I., Wenz, T., Bender, A., Aichler, M., Janik, D., Neff, F., Walch, A.K.,
Quintanilla-Fend, L., Floß, T., Bekeredjian, R., Gailus-Durner, V., Fuchs, H., Wurst, W., Meitinger, T.,
Prokisch, H., Hrabě de Angelis, M., Klopstock, T.°: MTO1-deficient mouse model mirrors the human
phenotype showing complex I defect and cardiomyopathy. PLoS ONE 9:e114918 (2014)
Beelen, R.°, Hoek, G., Raaschou-Nielsen, O., Stafoggia, M., Andersen, Z.J., Weinmayr, G., Hoffmann, B.,
Wolf, K., Samoli, E., Fischer, P.H., Nieuwenhuijsen, M.J., Xun, W.W., Katsouyanni, K., Dimakopoulou, K.,
Marcon, A., Vartiainen, E., Lanki, T., Yli-Tuomi, T., Oftedal, B., Schwarze, P.E., Nafstad, P., de Faire, U.,
Pedersen, N.L., Ostenson, C.G., Fratiglioni, L., Penell, J., Korek, M., Pershagen, G., Eriksen, K.T., Overvad,
K., Sørensen, M., Eeftens, M., Peeters, P.H., Meliefste, K., Wang, M., Bueno-de-Mesquita, H.B., Sugiri, D.,
Krämer, U., Heinrich, J., de Hoogh, K., Key, T., Peters, A., Hampel, R., Concin, H., Nagel, G., Jaensch, A.,
Ineichen, A., Tsai, M.Y., Schaffner, E., Probst-Hensch, N.M., Schindler, C., Ragettli, M.S., Vilier, A.,
Clavel-Chapelon, F., Declercq, C., Ricceri, F., Sacerdote, C., Galassi, C., Migliore, E., Ranzi, A., Cesaroni,
G., Badaloni, C., Forastiere, F., Katsoulis, M., Trichopoulou, A., Keuken, M., Jedynska, A., Kooter, I.M.,
Kukkonen, J.V.K., Sokhi, R.S., Vineis, P., Brunekreef, B.: Natural-cause mortality and long-term exposure to
particle components: An analysis of 19 European cohorts within the multi-center ESCAPE project. Environ.
Health Perspect. 123, 525-533 (2015)
page 22 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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Behr, E.R.°, Savio-Galimberti, E., Barc, J., Holst, A.G., Petropoulou, E., Prins, B.P., Jabbari, J., Torchio, M.,
Berthet, M., Mizusawa, Y., Yang, T., Nannenberg, E.A., Dagradi, F., Weeke, P., Bastiaenan, R., Ackerman,
M.J., Haunso, S., Leenhardt, A., Kääb, S., Probst, V., Redon, R., Sharma, S., Wilde, A.A., Tfelt-Hansen, J.,
Schwartz, P., Roden, D.M., Bezzina, C.R., Olesen, M.S., Darbar, D., Guicheney, P., Crotti, L., Jamshidi, Y.:
Role of common and rare variants in SCN10A: Results from the Brugada syndrome QRS locus gene
discovery collaborative study. Cardiovasc. Res. 106, 520-529 (2015)
Beleggia, F., Li, Y., Fan, J., Elcioğlu, N.H., Toker, E., Wieland, T., Maumenee, I.H., Akarsu, N.A., Meitinger,
T., Strom, T.M., Lang, R., Wollnik, B.°: CRIM1 haploinsufficiency causes defects in eye development in
human and mouse. Hum. Mol. Genet. 24, 2267-2273 (2015)
Bender, J., Engeholm, M., Ederer, M.S., Breu, J., Møller, T.C., Michalakis, S., Rasko, T., Wanker, E.E., Biel,
M., Martinez, K.L., Wurst, W., Deussing, J.M.°: Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1)
clustering with MAGUKs is mediated via its C-terminal PDZ binding motif. PLoS ONE 10:e0136768 (2015)
Berti, L., Irmler, M., Zdichavsky, M., Meile, T., Böhm, A., Stefan, N., Fritsche, A., Beckers, J.,
Königsrainer, A., Häring, H.-U., Hrabě de Angelis, M., Staiger, H.°: Fibroblast growth factor 21 is elevated
in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of
human abdominal subcutaneous adipocytes. Mol. Metab. 4, 519-527 (2015)
Bigert, C., Gustavsson, P., Straif, K., Pesch, B., Brüning, T., Kendzia, B., Schüz, J., Stücker, I., Guida, F.,
Brüske, I., Wichmann, H.-E., Pesatori, A.C., Landi, M.T., Caporaso, N., Tse, L.A., Yu, I.T., Siemiatycki, J.,
Pintos, J., Merletti, F., Mirabelli, D., Simonato, L., Jockel, K.H., Ahrens, W., Pohlabeln, H., Tardón, A.,
Zaridze, D., Field, J., 't Mannetje, A., Pearce, N., McLaughlin, J., Demers, P., Szeszenia-Dabrowska, N.,
Lissowska, J., Rudnai, P., Fabianova, E., Stanescu Dumitru, R., Bencko, V., Foretova, L., Janout, V.,
Boffetta, P., Forastiere, F., Bueno-de-Mesquita, B., Peters, S., Vermeulen, R., Kromhout, H., Olsson, A.C.°:
Lung cancer risk among cooks when accounting for tobacco smoking: S pooled analysis of case-control
studies from Europe, Canada, New Zealand, and China. J. Occup. Environ. Med. 57, 202-209 (2015)
Bind, M.A.°, Coull, B.A., Peters, A., Baccarelli, A.A., Tarantini, L., Cantone, L., Vokonas, P.S., Koutrakis, P.,
Schwartz, J.D.: Beyond the mean: Quantile regression to explore the association of air pollution with
gene-specific methylation in the normative aging study. Environ. Health Perspect. 123, 759-765 (2015)
Bluher, A., Devan, W.J., Holliday, E.G., Nalls, M., Parolo, S., Bione, S., Giese, A.K., Boncoraglio, G.B.,
Maguire, J.M., Müller-Nurasyid, M., Gieger, C., Meschia, J.F., Rosand, J., Rolfs, A., Kittner, S.J., Mitchell,
B.D., O'Connell, J.R., Cheng, Y.C.°: Heritability of young- and old-onset ischaemic stroke. Eur. J. Neurol. 22,
1488-1491 (2015)
Bögershausen, N.#, Tsai, I.C.#, Pohl, E., Kiper, P., Beleggia, F., Percin, E.F., Keupp, K., Matchan, A., Milz,
E., Alanay, Y., Kayserili, H., Liu, Y., Banka, S., Kranz, A., Zenker, M., Wieczorek, D., Elcioğlu, N.H.,
Prontera, P., Lyonnet, S., Meitinger, T., Stewart, A.F., Donnai, D., Strom, T.M., Boduroglu, K., Yigit, G., Li,
Y., Katsanis, N., Wollnik, B.°: RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome. J. Clin.
Invest. 125, 3585-3599 (2015)
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° corresponding authors
HMGU authors are given in bold letters
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Bönisch, C., Irmler, M., Brachthäuser, L., Neff, F., Bamberger, M.T., Marschall, S., Hrabě de Angelis,
M., Beckers, J.: Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as
observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring. Mamm. Genome
27, 17-28 (2015)
Boulet, M.M., Chevrier, G., Grenier-Larouche, T., Pelletier, M.P., Nadeau, M., Scarpa, J., Prehn, C.,
Marette, A., Adamski, J., Tchernof, A.°: Alterations of plasma metabolite profiles related to adipose tissue
distribution and cardiometabolic risk. Am. J. Physiol. Endocrinol. Metab. 309, E736-E746 (2015)
Bramswig, N.C.°, Ockeloen, C.W., Czeschik, J.C., van Essen, A.J., Pfundt, R., Smeitink, J., Poll-The, B.T.,
Engels, H., Strom, T.M., Wieczorek, D., Kleefstra, T., Lüdecke, H.J.: ‘Splitting versus lumping’:
Temple–Baraitser and Zimmermann–Laband syndromes. Hum. Genet. 134, 1089-1097 (2015)
Bramswig, N.C.°, Lüdecke, H.J., Alanay, Y., Albrecht, B., Barthelmie, A., Boduroglu, K., Braunholz, D.,
Caliebe, A., Chrzanowska, K., Czeschik, J.C., Endele, S.U., Graf, E., Guillén-Navarro, E., Kiper, P.O.S.,
López-González, V., Parenti, I., Pozojevic, J., Ü̈tine, G.E., Wieland, T., Kaiser, F.J., Wollnik, B., Strom,
T.M., Wieczorek, D.: Exome sequencing unravels unexpected differential diagnoses in individuals with the
tentative diagnosis of Coffin–Siris and Nicolaides–Baraitser syndromes. Hum. Genet. 134, 553-568 (2015)
Brandl, C., Ortiz, O., Röttig, B., Wefers, B., Wurst, W.°, Kühn, R.°: Creation of targeted genomic deletions
using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos. FEBS Open Bio 5, 26-35 (2015)
Brea-Calvo, G., Haack, T.B., Karall, D., Ohtake, A., Invernizzi, F., Carrozzo, R., Kremer, L.S., Dusi, S.,
Fauth, C., Scholl-Bürgi, S., Graf, E., Ahting, U., Resta, N., Laforgia, N., Verrigni, D., Okazaki, Y., Kohda, M.,
Martinelli, D., Freisinger, P., Strom, T.M., Meitinger, T., Lamperti, C., Lacson, A., Navas, P., Mayr, J.A.,
Bertini, E., Murayama, K., Zeviani, M., Prokisch, H.°, Ghezzi, D.°: COQ4 mutations cause a broad spectrum
of mitochondrial disorders associated with CoQ10 deficiency. Am. J. Hum. Genet. 96, 309-317 (2015)
Breen, M.S., Long, T.C., Schultz, B.D., Williams, R.W., Richmond-Bryant, J., Breen, M., Langstaff, J.E.,
Devlin, R.B., Schneider, A.E., Burke, J.M., Batterman, S.A., Meng, Q.Y.: Air pollution Exposure Model for
Individuals (EMI) in health studies: Evaluation for ambient PM2.5 in Central North Carolina. Environ. Sci.
Technol. 49, 14184-14194 (2015)
Brenndörfer, J.°, Altmann, A., Widner-Andrä, R., Pütz, B., Czamara, D., Tilch, E., Kam-Thong, T., Weber, P.,
Rex-Haffner, M., Bettecken, T., Bültmann, A., Müller-Myhsok, B., Binder, E.E., Landgraf, R., Czibere, L.:
Connecting anxiety and genomic copy number variation: A genome-wide analysis in CD-1 mice. PLoS ONE
10:e0128465 (2015)
Brina, D.°, Miluzio, A., Ricciardi, S., Clarke, K., Davidsen, P.K., Viero, G., Tebaldi, T., Offenhäuser, N.,
Rozman, J., Rathkolb, B., Neschen, S., Klingenspor, M., Wolf, E., Gailus-Durner, V., Fuchs, H., Hrabě
de Angelis, M., Quattrone, A., Falciani, F., Biffo, S.°: eIF6 coordinates insulin sensitivity and lipid
metabolism by coupling translation to transcription. Nat. Commun. 6:8261 (2015)
Brugger, M., Strauch, K.°: Fast linkage analysis with MOD scores using algebraic calculation. Hum. Hered.
78, 179-194 (2014)
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Brænne, I. , Kleinecke, M. , Reiz, B., Graf, E., Strom, T.M., Wieland, T., Fischer, M., Kessler, T.,
Hengstenberg, C., Meitinger, T., Erdmann, J.°, Schunkert, H.: Systematic analysis of variants related to
familial hypercholesterolemia in families with premature myocardial infarction. Eur. J. Hum. Genet. 24,
191-197 (2015)
Budde, K., Gök, Ö.-N., Pietzner, M., Meisinger, C., Leitzmann, M., Nauck, M., Köttgen, A., Friedrich, N.°:
Quality assurance in the pre-analytical phase of human urine samples by 1H-NMR spectroscopy. Arch.
Biochem. Biophys. 589, 10-17 (2016) [published online 2015]
Burkart, K.°, Meier, F., Schneider, A.E., Breitner, S., Canario, P., Alcoforado, M.J., Scherer, D., Endlicher,
W.: Modification of heat-related mortality in an elderly urban population by vegetation (urban green) and
proximity to water (urban blue): Evidence from Lisbon, Portugal. Environ. Health Perspect., DOI:
10.1289/ehp.1409529 (2015)
CARDIoGRAMplusC4D Consortium (Nikpay, M.#, Goel, A.#, Won, H.#, Hall, L.M.#, Willenborg, C.#, Kanoni,
S.#, Saleheen, D.#, Gieger, C., Meitinger, T., Peters, A., Watkins, H.°, Kathiresan, S.°, MacPherson, R.°): A
comprehensive 1000 genomes–based genome-wide association meta-analysis of coronary artery disease.
Nat. Genet. 47, 1121-1130 (2015)
Cernilogar, F.M.°, di Giaimo, R., Rehfeld, F., Cappello, S., Lie, D.C.: RNA interference
machinery-mediated gene regulation in mouse adult neural stem cells. BMC Neurosci. 16:60 (2015)
Chambers, J.C.°, Loh, M., Lehne, B., Drong, A., Kriebel, J., Motta, V., Wahl, S., Elliott, H.R., Rota, F., Scott,
W.R., Zhang, W., Tan, S.T., Campanella, G., Chadeau-Hyam, M., Yengo, L., Richmond, R.C.,
Adamowicz-Brice, M., Afzal, U., Bozaoglu, K., Mok, Z.Y., Ng, H.K., Pattou, F., Prokisch, H., Rozario, M.A.,
Tarantini, L., Abbott, J., Ala-Korpela, M., Albetti, B., Ammerpohl, O., Bertazzi, P.A., Blancher, C., Caiazzo,
R., Danesh, J., Gaunt, T.R., de Lusignan, S., Gieger, C., Illig, T., Jha, S., Jones, S., Jowett, J., Kangas, A.J.,
Kasturiratne, A., Kato, N., Kotea, N., Kowlessur, S., Pitkäniemi, J., Punjabi, P., Saleheen, D., Schafmayer,
C., Soininen, P., Tai, E.S., Thorand, B., Tuomilehto, J., Wickremasinghe, A.R., Kyrtopoulos, S.A., Aitman,
T.J., Herder, C., Hampe, J., Cauchi, S., Relton, C.L., Froguel, P., Soong, R., Vineis, P., Jarvelin, M.R., Scott,
J., Grallert, H., Bollati, V., Elliott, P., McCarthy, M.I., Kooner, J.S.: Epigenome-wide association of DNA
methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: A
nested case-control study. Lancet Diabet. Endocrinol. 3, 526-534 (2015)
Chan, Y.°, Salem, R.M., Hsu, Y.H., McMahon, G., Pers, T.H., Vedantam, S., Esko, T., Guo, M.H., Lim, E.T.,
GIANT Consortium (Albrecht, E., Gieger, C., Grallert, H., Heid, I.M., Illig, T., Müller-Nurasyid, M., Peters,
A., Thorand, B., Wichmann, H.-E.), Franke, L., Smith, G.D., Strachan, D.P., Hirschhorn, J.N.°:
Genome-wide analysis of body proportion classifies height-associated variants by mechanism of action and
implicates genes important for skeletal development. Am. J. Hum. Genet. 96, 695-708 (2015)
Chen, S.Y., Wu, C.F., Lee, J.H., Hoffmann, B., Peters, A., Brunekreef, B., Chu, D.C., Chan, C.C.°:
Associations between long-term air pollutant exposures and blood pressure in elderly residents of Taipei city:
A cross-sectional study. Environ. Health Perspect. 123, 779-784 (2015)
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Chen, Y.-C., Auer-Grumbach, M., Matsukawa, S., Zitzelsberger, M., Themistocleous, A.C., Strom, T.M.,
Samara, C., Moore, A.W., Cho, L.T., Young, G.T., Weiss, C., Schabhüttl, M., Stucka, R., Schmid, A.B.,
Parman, Y., Graul-Neumann, L., Heinritz, W., Passarge, E., Watson, R.M., Hertz, J.M., Moog, U.,
Baumgartner, M.R., Valente, E.M., Pereira, D., Restrepo, C.M., Katona, I., Dusl, M., Stendel, C., Wieland,
T., Stafford, F., Reimann, F., von Au, K., Finke, C., Willems, P.J., Nahorski, M.S., Shaikh, S.S., Carvalho,
O.P., Nicholas, A.K., Karbani, G., McAleer, M.A., Cilio, M.R., McHugh, J.C., Murphy, S.M., Irvine, A.D.,
Jensen, U.B., Windhager, R., Weis, J., Bergmann, C., Rautenstrauss, B., Baets, J., de Jonghe, P., Reilly,
M.M., Kropatsch, R., Kurth, I., Chrast, R., Michiue, T., Bennett, D.L., Woods, C.G.°, Senderek, J.°:
Transcriptional regulator PRDM12 is essential for human pain perception. Nat. Genet. 47, 803-808 (2015)
Cheng, Y., Perocchi, F.°: ProtPhylo: Identification of protein-phenotype and protein-protein functional
associations via phylogenetic profiling. Nucleic Acids Res. 41, W160-W168 (2015)
Chu, V.T., Weber, T., Wefers, B., Wurst, W., Sander, S., Rajewsky, K.°, Kühn, R.°: Increasing the efficiency
of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells. Nat.
Biotechnol. 33, 543-548 (2015)
Colombo, M.°, Meisinger, C., Amann, U., Heier, M., von Scheidt, W., Kuch, B., Peters, A., Kirchberger, I.:
Association of obesity and long-term mortality in patients with acute myocardial infarction with and without
diabetes mellitus: Results from the MONICA/KORA myocardial infarction registry. Cardiovasc. Diabetol.
14:24 (2015)
Conlon, T.M., Bartel, J., Ballweg, K., Günter, S., Prehn, C., Krumsiek, J., Meiners, S., Theis, F.J.,
Adamski, J., Eickelberg, O., Yildirim, A.Ö.°: Metabolomics screening identifies reduced L-carnitine to be
associated with progressive emphysema. Clin. Sci. 130, 273-287 (2015)
Cruz Perez, C., Lauri, A., Symvoulidis, P., Cappetta, M., Erdmann, A., Westmeyer, G.G.°: Calcium
neuroimaging in behaving zebrafish larvae using a turn-key light field camera. J. Biomed. Opt. 20:96009
(2015)
Cyrys, J.°, Peters, A., Soentgen, J., Gu, J., Wichmann, H.-E.: Umweltzonen. Umweltmed. Hygiene
Arbeitsmed. 20, 33-57 (2015)
Danhauser, K., Herebian, D., Haack, T.B., Rodenburg, R.J., Strom, T.M., Meitinger, T., Klee, D.,
Mayatepek, E., Prokisch, H., Distelmaier, F.°: Fatal neonatal encephalopathy and lactic acidosis caused by
a homozygous loss-of-function variant in COQ9. Eur. J. Hum. Genet. 24, 450-454 (2016) [published online
2015]
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#
Dankowski, T. , Buck, D. , Andlauer, T.F., Antony, G., Bayas, A., Bechmann, L., Berthele, A., Bettecken, T.,
Chan, A., Franke, A., Gold, R., Graetz, C., Haas, J., Hecker, M., Herms, S., Infante-Duarte, C., Jockel, K.H.,
Kieseier, B.C., Knier, B., Knop, M., Kümpfel, T., Lichtner, P., Lieb, W., Lill, C.M., Limmroth, V., Linker, R.A.,
Loleit, V., Meuth, S.G., Moebus, S., Müller-Myhsok, B., Nischwitz, S., Nöthen, M.M., Paul, F., Pütz, M., Ruck,
T., Salmen, A., Stangel, M., Stellmann, J.P., Strauch, K., Stürner, K.H., Tackenberg, B., Then Bergh, F.,
Tumani, H., Waldenberger, M., Weber, F., Wiendl, H., Wildemann, B., Zettl, U.K., Ziemann, U., Zipp, F.,
Hemmer, B., Ziegler, A.°: Successful replication of GWAS hits for multiple sclerosis in 10,000 Germans using
the exome array. Genet. Epidemiol. 39, 601-608 (2015)
Day, F.R., Ruth, K.S., Thompson, D.J., Lunetta, K.L., Pervjakova, N., Chasman, D.I., Stolk, L., Finucane,
H.K., Sulem, P., Bulik-Sullivan, B., Esko, T., Johnson, A.D., Elks, C.E., Franceschini, N., He, C., Altmaier,
E.M., Brody, J.A., Franke, L.L., Huffman, J.E., Keller, M.F., McArdle, P.F., Nutile, T., Porcu, E., Robino, A.,
Rose, L.M., Schick, U.M., Smith, J.A., Teumer, A., Traglia, M., Vuckovic, D., Yao, J., Zhao, W., Albrecht, E.,
Amin, N., Corre, T., Hottenga, J.J., Mangino, M., Smith, A.V., Tanaka, T., Abecasis, G.R., Andrulis, I.L.,
Anton-Culver, H., Antoniou, A.C., Arndt, V., Arnold, A.M., Barbieri, C., Beckmann, M.W., Beeghly-Fadiel, A.,
Benítez, J., Bernstein, L., Bielinski, S.J., Blomqvist, C., Boerwinkle, E., Bogdanova, N.V., Bojesen, S.E.,
Bolla, M.K., Borresen-Dale, A.L., Boutin, T.S., Brauch, H., Brenner, H., Brüning, T., Burwinkel, B., Campbell,
A., Campbell, H., Chanock, S.J., Chapman, J.R., Chen, Y.D., Chenevix-Trench, G., Couch, F.J., Coviello,
A.D., Cox, A., Czene, K., Darabi, H., de Vivo, I., Demerath, E.W., Dennis, J., Devilee, P., Dörk, T.,
Dos-Santos-Silva, I., Dunning, A.M., Eicher, J.D., Fasching, P.A., Faul, J.D., Figueroa, J., Flesch-Janys, D.,
Gandin, I., Garcia, M.E., Garcia-Closas, M., Giles, G.G., Girotto, G.G., Goldberg, M.S., González-Neira, A.,
Goodarzi, M.O., Grove, M.L., Gudbjartsson, D.F., Guénel, P., Guo, X., Haiman, C.A., Hall, P., Hamann, U.,
Henderson, B.E., Hocking, L.J., Hofman, A., Homuth, G., Hooning, M.J., Hopper, J.L., Hu, F.B., Huang, J.,
Humphreys, K., Hunter, D.J., Jakubowska, A., Jones, S.E., Kabisch, M., Karasik, D., Knight, J.A., Kolcic, I.,
Kooperberg, C., Kosma, V.M., Kriebel, J., Kristensen, V., Lambrechts, D., Langenberg, C., Li, J., Li, X.,
Lindström, S., Liu, Y., Luan, J., Lubinski, J., Mägi, R., Mannermaa, A., Manz, J., Margolin, S., Marten, J.,
Martin, N.G., Masciullo, C., Meindl, A., Michailidou, K., Mihailov, E., Milani, L., Milne, R.L., Müller-Nurasyid,
M., Nalls, M., Neale, B.M., Nevanlinna, H., Neven, P., Newman, A.B., Nordestgaard, B.G., Olson, J.E.,
Padmanabhan, S., Peterlongo, P., Peters, U., Petersmann, A., Peto, J., Pharoah, P.D., Pirastu, N.N., Pirie,
A., Pistis, G., Polasek, O., Porteous, D.J., Psaty, B.M., Pylkäs, K., Radice, P., Raffel, L.J., Rivadeneira, F.,
Rudan, I., Rudolph, A., Ruggiero, D., Sala, C.F., Sanna, S., Sawyer, E.J., Schlessinger, D., Schmidt, M.K.,
Schmidt, F., Schmutzler, R.K., Schoemaker, M.J., Scott, R.A., Seynaeve, C.M., Simard, J., Sorice, R.,
Southey, M.C., Stöckl, D., Strauch, K., Swerdlow, A., Taylor, K.D., Thorsteinsdottir, U., Toland, A.E.,
Tomlinson, I., Truong, T., Tryggvadottir, L., Turner, S.T., Vozzi, D., Wang, Q., Wellons, M., Willemsen, G.,
Wilson, J.F., Winqvist, R., Wolffenbuttel, B.B., Wright, A.F., Yannoukakos, D., Zemunik, T., Zheng, W.,
Zygmunt, M., Bergmann, S., Boomsma, D.I., Buring, J.E., Ferrucci, L., Montgomery, G.W., Gudnason, V.,
Spector, T.D., van Duijn, C.M., Alizadeh, B.Z., Ciullo, M., Crisponi, L., Easton, D.F., Gasparini, P.P., Gieger,
C., Harris, T.B., Hayward, C., Kardia, S.L., Kraft, P., McKnight, B., Metspalu, A., Morrison, A.C., Reiner, A.P.,
Ridker, P.M., Rotter, J.I., Toniolo, D., Uitterlinden, A.G., Ulivi, S., Völzke, H., Wareham, N.J., Weir, D.R.,
Yerges-Armstrong, L.M., Price, A.L., Stefansson, K., Visser, J.A., Ong, K.K., Chang-Claude, J., Murabito,
J.M., Perry, J.R.°, Murray, A.: Large-scale genomic analyses link reproductive aging to hypothalamic
signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nat. Genet. 47, 1294-1303 (2015)
page 27 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
#
#
#
#
de Ferrari, G.M. , Dusi, V. , Spazzolini, C. , Bos, J.M. , Abrams, D.J., Berul, C.I., Crotti, L., Davis, A.M.,
Eldar, M., Kharlap, M., Khoury, A., Krahn, A.D., Leenhardt, A., Moir, C.R., Odero, A., Olde Nordkamp, L.,
Paul, T., Rosés I Noguer, F., Shkolnikova, M., Till, J., Wilde, A.A., Ackerman, M.J.°, Schwartz, P.J.°: Clinical
management of catecholaminergic polymorphic ventricular tachycardia: The role of left cardiac sympathetic
denervation. Circulation 131, 2185-2193 (2015)
de Vries, P.S., Chasman, D.I., Sabater-Lleal, M., Chen, M.H., Huffman, J.E., Steri, M., Tang, W., Teumer, A.,
Marioni, R.E., Grossmann, V., Hottenga, J.J., Trompet, S., Müller-Nurasyid, M., Zhao, J.H., Brody, J.A.,
Kleber, M.E., Guo, X., Wang, J.J., Auer, P.L., Attia, J.R., Yanek, L.R., Ahluwalia, T.S., Lahti, J., Venturini, C.,
Tanaka, T., Bielak, L.F., Joshi, P.K., Rocanin-Arjo, A., Kolcic, I., Navarro, P., Rose, L.M., Oldmeadow, C.,
Riess, H., Mazur, J., Basu, S., Goel, A., Yang, Q., Ghanbari, M., Willemsen, G., Rumley, A., Fiorillo, E., de
Craen, A.J., Grotevendt, A., Scott, R.A., Taylor, K.D., Delgado, G.E., Yao, J., Kifley, A., Kooperberg, C.,
Qayyum, R., Lopez, L.M., Berentzen, T.L., Räikkönen, K., Mangino, M., Bandinelli, S., Peyser, P.A., Wild, S.,
Tregouet, D.A., Wright, A.F., Marten, J., Zemunik, T., Morrison, A.C., Sennblad, B., Tofler, G., de Maat,
M.P.M., de Geus, E.J., Lowe, G.D., Zoledziewska, M., Sattar, N., Binder, H., Völker, U., Waldenberger, M.,
Khaw, K.T., McKnight, B., Huang, J., Jenny, N.S., Holliday, E.G., Qi, L., McEvoy, M.G., Becker, D.M., Starr,
J.M., Sarin, A.P., Hysi, P.G., Hernandez, D.G., Jhun, M.A., Campbell, H., Hamsten, A., Rivadeneira, F.,
McArdle, W.L., Slagboom, P.E., Zeller, T., Koenig, W., Psaty, B.M., Haritunians, T., Liu, J., Palotie, A.,
Uitterlinden, A.G., Stott, D.J., Hofman, A., Franco, O.H., Polasek, O., Rudan, I., Morange, P.E., Wilson, J.F.,
Kardia, S.L., Ferrucci, L., Spector, T.D., Eriksson, J.G., Hansen, T., Deary, I.J., Becker, L.C., Scott, R.J.,
Mitchell, P., Marz, W., Wareham, N.J., Peters, A., Greinacher, A., Wild, P.S., Jukema, J.W., Boomsma, D.I.,
Hayward, C., Cucca, F., Tracy, R., Watkins, H., Reiner, A.P., Folsom, A.R., Ridker, P.M., O'Donnell, C.J.,
Smith, N.L., Strachan, D.P., Dehghan, A.: A meta-analysis of 120,246 individuals identifies 18 new loci for
fibrinogen concentration. Hum. Mol. Genet. 25, 358-370 (2016) [published online 2015]
Dean-Ben, X.L., Stiel, A.C., Jiang, Y., Ntziachristos, V., Westmeyer, G.G., Razansky, D.°: Light fluence
normalization in turbid tissues via temporally unmixed multispectral optoacoustic tomography. Opt. Lett. 40,
4691-4694 (2015)
Deckert, A.°, Winkler, V.°, Meisinger, C.°, Heier, M.°, Becher, H.°: Suicide and external mortality pattern in a
cohort of migrants from the former Soviet Union to Germany. J. Psychiatr. Res. 63, 36-42 (2015)
Dégano, I.R., Subirana, I., Torre, M., Grau, M., Vila, J., Fusco, D., Kirchberger, I., Ferrieres, J., Malmivaara,
A., Azevedo, A., Meisinger, C., Bongard, V., Farmakis, D., Davoli, M., Häkkinen, U., Araujo, C., Lekakis, J.,
Elosua, R., Marrugat, J.°: A European benchmarking system to evaluate in-hospital mortality rates in acute
coronary syndrome: The EURHOBOP project. Int. J. Cardiol. 182, 509-516 (2015)
Dégano, I.R., Salomaa, V., Veronesi, G., Ferrieres, J., Kirchberger, I., Laks, T., Havulinna, A.S., Ruidavets,
J.B., Ferrario, M.M., Meisinger, C., Elosua, R., Marrugat, J.°, Acute Myocardial Infarction Trends in Europe
(AMITIE) Study Investigators: Twenty-five-year trends in myocardial infarction attack and mortality rates, and
case-fatality, in six European populations. Heart 101, 1413-1421 (2015)
page 28 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
#
#
Deng, T. , Zhu, Z.I. , Zhang, S., Postnikov, Y., Huang, D., Horsch, M., Furusawa, T., Beckers, J., Rozman,
J., Klingenspor, M., Amarie, O.V., Graw, J., Rathkolb, B., Wolf, E., Adler, T., Busch, D.H.,
Gailus-Durner, V., Fuchs, H., Hrabě de Angelis, M., van der Velde, A., Tessarollo, L., Ovcherenko, I.,
Landsman, D., Bustin, M.°: Functional compensation among HMGN variants modulates the DNase I
hypersensitive sites at enhancers. Genome Res. 25, 1295-1308 (2015)
Derdak, S., Sabrautzki, S., Hrabě de Angelis, M., Gut, M.O., Gut, I.G., Beltran, S.°: Genomic
characterization of mutant laboratory mouse strains by exome sequencing and annotation lift-over. BMC
Genomics 16:351 (2015)
Diakopoulos, K.N., Lesina, M., Wörmann, S., Song, L., Aichler, M., Schild, L., Artati, A., Römisch-Margl,
W., Wartmann, T., Fischer, R., Kabiri, Y., Zischka, H., Halangk, W., Demir, I.E., Pilsak, C., Walch, A.K.,
Mantzoros, C.S., Steiner, J.M., Erkan, M., Schmid, R.M., Witt, H., Adamski, J., Algül, H.°: Impaired
autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.
Gastroenterology 148, 626-638 (2015)
Diaz-Lacava, A.N.°, Walier, M., Holler, D., Steffens, M., Gieger, C., Furlanello, C., Lamina, C., Wichmann,
H.-E., Becker, T.: Genetic geostatistical framework for spatial analysis of fine-scale genetic heterogeneity in
modern populations: Results from the KORA study. Int. J. Genomics 2015:693193 (2015)
#
#
Diener, S. , Schorpp, K.K. , Strom, T.M., Hadian, K.°, Lorenz-Depiereux, B.°: Development of a
cell-based assay to identify small molecule inhibitors of FGF23 signaling. Assay Drug Dev. Technol. 13,
476-487 (2015)
Distelmaier, F.°, Haack, T.B., Catarino, C.B., Gallenmüller, C., Rodenburg, R.J.T., Strom, T.M., Baertling,
F., Meitinger, T., Mayatepek, E., Prokisch, H.°, Klopstock, T.: MRPL44 mutations cause a slowly
progressive multisystem disease with childhood-onset hypertrophic cardiomyopathy. Neurogenetics 16,
319-323 (2015)
#
#
Domschke, K. , Akhrif, A. , Romanos, M., Bajer, C., Mainusch, M., Winkelmann, J., Zimmer, C., Neufang,
S.°: Neuropeptide S receptor gene variation differentially modulates fronto-limbic effective connectivity in
childhood and adolescence. Cereb. Cortex, DOI: 10.1093/cercor/bhv259 (2015)
Dostal, M.°, Pastorkova, A., Lanzinger, S., Schneider, A.E., Bastian, S., Senghaas, M., Erzen, Z., Novak,
J., Kolodnitska, T., Sram, R.J., Peters, A.: Health effects of ambient ultrafine particles - the project UFIREG
background. Cas. Lek. Cesk. 154, 176-180 (2015)
page 29 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
#
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Draisma, H.H. °, Pool, R. , Kobl, M., Jansen, R.C., Petersen, A.-K., Vaarhorst, A.A., Yet, I., Haller, T.,
Demirkan, A., Esko, T., Zhu, G., Böhringer, S., Beekman, M., van Klinken, J.B., Römisch-Margl, W., Prehn,
C., Adamski, J., de Craen, A.J., van Leeuwen, E.M., Amin, N., Dharuri, H., Westra, H.J., Franke, L., de
Geus, E.J., Hottenga, J.J., Willemsen, G., Henders, A.K., Montgomery, G.W., Nyholt, D.R., Whitfield, J.B.,
Penninx, B.W., Spector, T.D., Metspalu, A., Slagboom, P.E., van Dijk, K.W., 't Hoen, P.A., Strauch, K.,
Martin, N.G., van Ommen, G.J., Illig, T., Bell, J.T., Mangino, M., Suhre, K., McCarthy, M.I., Gieger, C.,
Isaacs, A., van Duijn, C.M., Boomsma, D.I.: Genome-wide association study identifies novel genetic variants
contributing to variation in blood metabolite levels. Nat. Commun. 6:7208 (2015)
Dutta, S., Krause, A., Vosberg, S., Herold, T., Ksienzyk, B., Quintanilla-Martinez, L., Tizazu, B., Chopra,
M., Graf, A., Krebs, S., Blum, H., Greif, P.A., Vetter, A., Metzeler, K.H., Rothenberg-Thurley, M., Schneider,
M.R., Dahlhoff, M., Spiekermann, K., Zimber-Strobl, U., Wolf, E., Bohlander, S.K.°: The target cell of
transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models. Leukemia,
DOI: 10.1038/leu.2015.349 (2015)
Elovainio, M.°, Taipale, T., Seppälä, I., Mononen, N., Raitoharju, E., Jokela, M., Pulkki-Råback, L., Illig, T.,
Waldenberger, M., Hakulinen, C., Hintsa, T., Kivimäki, M., Kähönen, M., Keltikangas-Järvinen, L., Raitakari,
O., Lehtimäki, T.: Activated immune-inflammatory pathways are associated with long-standing depressive
symptoms: Evidence from gene-set enrichment analyses in the Young Finns Study. J. Psychiatr. Res. 71,
120-125 (2015)
Emeny, R.T., Kasten-Jolly, J., Mondal, T., Lynes, M.A., Lawrence, D.A.°: Metallothionein differentially affects
the host response to Listeria infection both with and without an additional stress from cold-restraint. Cell
Stress Chaperones 20, 1013-1022 (2015)
Emeny, R.T.°, Huber, D., Bidlingmaier, M., Reincke, M., Klug, G., Ladwig, K.-H.°: Oxytocin-induced coping
with stressful life events in old age depends on attachment: Findings from the cross-sectional KORA Age
study. Psychoneuroendocrinology 56, 132-142 (2015)
Emerging Risk Factors Collaboration (di Angelantonio, E., Kaptoge, S., Wormser, D., Willeit, P., Butterworth,
A.S., Bansal, N., O'Keeffe, L.M., Gao, P., Wood, A.M., Burgess, S.L., Freitag, D.F., Pennells, L., Peters,
S.A., Hart, C.L., Håheim, L.L., Gillum, R.F., Nordestgaard, B.G., Psaty, B.M., Yeap, B.B., Knuiman, M.W.,
Nietert, P.J., Kauhanen, J., Salonen, J.T., Kuller, L.H., Simons, L.A., van der Schouw, Y.T., Barrett-Connor,
E., Selmer, R., Crespo, C.J., Rodriguez, B., Verschuren, W.M., Salomaa, V., Svärdsudd, K., van der Harst,
P., Björkelund, C., Wilhelmsen, L., Wallace, R.B., Brenner, H., Amouyel, P., Barr, E.L., Iso, H., Onat, A.,
Trevisan, M., D'Agostino, R.B., Cooper, C., Kavousi, M., Welin, L., Roussel, R., Hu, F.B., Sato, S., Davidson,
K.W., Howard, B.V., Leening, M., Rosengren, A., Dörr, M., Deeg, D.J., Kiechl, S., Stehouwer, C.D., Nissinen,
A., Giampaoli, S., Donfrancesco, C., Kromhout, D., Price, J.F., Peters, A., Meade, T.W., Casiglia, E., Lawlor,
D.A., Gallacher, J., Nagel, D., Franco, O.H., Assmann, G., Dagenais, G.R., Jukema, J.W., Sundström, J.,
Woodward, M., Brunner, E.J., Khaw, K.T., Wareham, N.J., Whitsel, E.A., Njølstad, I., Hedblad, B.,
Wassertheil-Smoller, S., Engström, G., Rosamond, W.D., Selvin, E., Sattar, N., Thompson, S.G., Danesh,
J.°): Association of cardiometabolic multimorbidity with mortality. JAMA 314, 52-60 (2015)
page 30 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Escott-Price, V., Nalls, M.A., Morris, H.R., Lubbe, S., Brice, A., Gasser, T., Heutink, P., Wood, N.W., Hardy,
J., Singleton, A.B., Williams, N.M.°, International Parkinson's Disease Genomics Consortium (IPDGC) (Illig,
T., Lichtner, P.): Polygenic risk of Parkinson disease is correlated with disease age at onset. Ann. Neurol.
77, 582-591 (2015)
EUGenMed, Cardiovascular Clinical Study Group, Regitz-Zagrosek, V.°, Oertelt-Prigione, S., Prescott, E.,
Franconi, F., Gerdts, E., Foryst-Ludwig, A., Maas, A.H., Kautzky-Willer, A., Knappe-Wegner, D., Kintscher,
U., Ladwig, K.-H., Schenck-Gustafsson, K., Stangl, V.: Gender in cardiovascular diseases: Impact on clinical
manifestations, management, and outcomes. Eur. Heart J. 37, 24-34 (2016) [published online 2015]
Evangelisti, C.°, de Biase, D., Kurelac, I., Ceccarelli, C., Prokisch, H., Meitinger, T., Caria, P., Vanni, R.,
Romeo, G., Tallini, G., Gasparre, G., Bonora, E.: A mutation screening of oncogenes, tumor suppressor
gene TP53 and nuclear encoded mitochondrial complex I genes in oncocytic thyroid tumors. BMC Cancer
15:157 (2015)
Falk, M.J.°, Shen, L., Gonzalez, M., Leipzig, J., Lott, M.T., Stassen, A.P., Diroma, M.A., Navarro-Gomez, D.,
Yeske, P., Bai, R., Boles, R.G., Brilhante, V., Ralph, D., DaRe, J.T., Shelton, R., Terry, S.F., Zhang, Z.,
Copeland, W.C., van Oven, M., Prokisch, H., Wallace, D.C., Attimonelli, M., Krotoski, D., Zuchner, S., Gai,
X.°: Mitochondrial Disease Sequence Data Resource (MSeqDR): A global grass-roots consortium to facilitate
deposition, curation, annotation, and integrated analysis of genomic data for the mitochondrial disease
clinical and research communities. Mol. Genet. Metab. 114, 388-396 (2015)
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#
Fall, T. , Hägg, S. , Ploner, A., Mägi, R., Fischer, K., Draisma, H.H., Sarin, A.P., Benyamin, B., Ladenvall, C.,
Åkerlund, M., Kals, M., Esko, T., Nelson, C.P., Kaakinen, M., Huikari, V., Mangino, M., Meirhaeghe, A.,
Kristiansson, K., Nuotio, M.L., Kobl, M., Grallert, H., Dehghan, A., Kuningas, M., de Vries, P.S., de Bruijn,
R.F., Willems, S.M., Heikkilä, K., Silventoinen, K., Pietiläinen, K.H., Legry, V., Giedraitis, V., Goumidi, L.,
Syvanen, A.C., Strauch, K., Koenig, W., Lichtner, P., Herder, C., Palotie, A., Menni, C., Uitterlinden, A.G.,
Kuulasmaa, K., Havulinna, A.S., Moreno, L.A., Gonzalez-Gross, M., Evans, A., Tregouet, D.A., Yarnell, J.W.,
Virtamo, J., Ferrieres, J., Veronesi, G., Perola, M., Arveiler, D., Brambilla, P., Lind, L., Kaprio, J., Hofman, A.,
Stricker, B.H., van Duijn, C.M., Ikram, M.A., Franco, O.H., Cottel, D., Dallongeville, J., Hall, A.S., Jula, A.,
Tobin, M.D., Penninx, B.W., Peters, A., Gieger, C., Samani, N.J., Montgomery, G.W., Whitfield, J.B., Martin,
N.G., Groop, L., Spector, T.D., Magnusson, P.K., Amouyel, P., Boomsma, D.I., Nilsson, P.M., Jarvelin, M.R.,
Lyssenko, V., Metspalu, A., Strachan, D.P., Salomaa, V., Ripatti, S., Pedersen, N.L., Prokopenko, I.,
McCarthy, M.I., Ingelsson, E.°: Age- and sex-specific causal effects of adiposity on cardiovascular risk
factors. Diabetes 64, 1841-1852 (2015)
Fasan, A.°, Haferlach, C., Eder, C., Alpermann, T., Quante, A.S., Peters, A., Kern, W., Haferlach, T.,
Schnittger, S.: Evaluation of IDH1G105 polymorphism as prognostic marker in intermediate-risk AML. Ann.
Hematol. 94, 1991-2001 (2015)
page 31 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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#
#
Fischer, A. , Ellinghaus, D. , Nutsua, M., Hofmann, S., Montgomery, C.G., Iannuzzi, M.C., Rybicki, B.A.,
Petrek, M., Mrazek, F., Pabst, S., Grohe, C., Grunewald, J., Ronninger, M., Eklund, A., Padyukov, L.,
Mihailovic-Vucinic, V., Jovanovic, D.L., Sterclova, M., Homolka, J., Nöthen, M.M., Herms, S., Gieger, C.,
Strauch, K., Winkelmann, J., Boehm, B.O., Brand, S., Büning, C., Schürmann, M., Ellinghaus, E., Baurecht,
H., Lieb, W., Nebel, A., Müller-Quernheim, J., Franke, A., Schreiber, S.°: Identification of immune-relevant
factors conferring sarcoidosis genetic risk. Am. J. Respir. Crit. Care Med. 192, 727-736 (2015)
Flaquer, A.°, Baumbach, C., Ladwig, K.-H., Kriebel, J., Waldenberger, M., Grallert, H., Baumert, J.J.,
Meitinger, T., Kruse, J., Peters, A., Emeny, R.T., Strauch, K.: Mitochondrial genetic variants identified to
be associated with posttraumatic stress disorder. Transl. Psychiatry 5:e524 (2015)
Flaquer, A.°, Rospleszcz, S., Reischl, E., Zeilinger, S., Prokisch, H., Meitinger, T., Meisinger, C.,
Peters, A., Waldenberger, M., Grallert, H., Strauch, K.: Mitochondrial GWA analysis of lipid profile
identifies genetic variants to be associated with HDL cholesterol and triglyceride levels. PLoS ONE
10:e0126294 (2015)
Flentje, H.°, Briel, B., Beck, C., Collaud Coen, M., Fricke, M., Cyrys, J., Gu, J., Pitz, M., Thomas, W.:
Identification and monitoring of Saharan dust: An inventory representative for South Germany since 1997.
Atmos. Environ. 109, 87-96 (2015)
Francalacci, P.°, Sanna, D., Useli, A., Berutti, R., Barbato, M., Whalen, M.B., Angius, A., Sidore, C., Alonso,
S., Tofanelli, S., Cucca, F.: Detection of phylogenetically informative polymorphisms in the entire
euchromatic portion of human Y chromosome from a Sardinian sample. BMC Res. Notes 8:177 (2015)
Freischmidt, A., Wieland, T., Richter, B., Ruf, W., Schäffer, V., Müller, K., Marroquin, N., Nordin, F., Hübers,
A., Weydt, P., Pinto, S., Press, R., Millecamps, S., Molko, N., Bernard, E., Desnuelle, C., Soriani, M.H.,
Dorst, J., Graf, E., Nordström, U., Feiler, M.S., Putz, S., Böckers, T.M., Meyer, T., Winkler, A.S.,
Winkelmann, J., de Carvalho, M., Thal, D.R., Otto, M., Brännström, T., Volk, A.E., Kursula, P., Danzer, K.M.,
Lichtner, P., Dikic, I., Meitinger, T., Ludolph, A.C., Strom, T.M., Andersen, P.M.°, Weishaupt, J.H.°:
Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nat. Neurosci. 18, 631-636
(2015)
Fugmann, M., Breier, M., Rottenkolber, M., Banning, F., Ferrari, U., Sacco, V., Grallert, H., Parhofer,
K.G., Seissler, J., Clavel, T., Lechner, A.°: The stool microbiota of insulin resistant women with recent
gestational diabetes, a high risk group for type 2 diabetes. Sci. Rep. 5:13212 (2015)
Fukusumi, Y.#, Meier, F.#, Götz, S.#, Matheus, F., Irmler, M., Beckervordersandforth, R., Faus-Kessler, T.,
Minina, E., Rauser, B., Zhang, J., Arenas, E., Andersson, E.A., Niehrs, C., Beckers, J., Simeone, A.,
Wurst, W.°, Prakash, N.°: Dickkopf3 promotes the differentiation of a rostrolateral midbrain dopaminergic
neuronal subset in vivo and from pluripotent stem cells in vitro in the mouse. J. Neurosci. 35, 13385-13401
(2015)
page 32 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Garrett, L., Zhang, J., Zimprich, A., Niedermeier, K.M., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis,
M., Vogt Weisenhorn, D.M., Wurst, W., Hölter, S.M.°: Conditional reduction of adult born
doublecortin-positive neurons reversibly impairs selective behaviors. Front. Behav. Neurosci. 9:302 (2015)
Gascón, S.#°, Murenu, E.#, Masserdotti, G., Ortega, F., Russo, G.L., Petrik, D., Deshpande, A., Heinrich,
C., Karow, M., Robertson, S.P., Schroeder, T., Beckers, J., Irmler, M., Berndt, C., Friedmann Angeli, J.P.,
Conrad, M., Berninger, B., Götz, M.°: Identification and successful negotiation of a metabolic checkpoint in
direct neuronal repogramming. Cell Stem Cell 18, 396-409 (2016) [published online 2015]
#
#
#
#
#
#
Gaulton, K.J. °, Ferreira, T. , Lee, Y. , Raimondo, A. , Mägi, R. , Reschen, M.E. , Mahajan, A., Locke, A.,
William Rayner, N., Robertson, N., Scott, R.A., Prokopenko, I., Scott, L.J., Green, T., Sparso, T., Thuillier, D.,
Yengo, L., Grallert, H., Wahl, S., Frånberg, M., Strawbridge, R.J., Kestler, H., Chheda, H., Eisele, L.,
Gustafsson, S., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Karssen, L.C., van Leeuwen, E.M., Willems,
S.M., Li, M., Chen, H., Fuchsberger, C., Kwan, P., Ma, C., Linderman, M., Lu, Y., Thomsen, S.K., Rundle,
J.K., Beer, N.L., van de Bunt, M., Chalisey, A., Kang, H.M., Voight, B.F., Abecasis, G.R., Almgren, P.,
Baldassarre, D., Balkau, B., Benediktsson, R., Blüher, M., Boeing, H., Bonnycastle, L.L., Bottinger, E.P.,
Burtt, N.P., Carey, J., Charpentier, G., Chines, P.S., Cornelis, M.C., Couper, D.J., Crenshaw, A.T., van Dam,
R.M., Doney, A.S., Dorkhan, M., Edkins, S., Eriksson, J.G., Esko, T., Eury, E., Fadista, J., Flannick, J.,
Fontanillas, P., Fox, C., Franks, P.W., Gertow, K., Gieger, C., Gigante, B., Gottesman, O., Grant, G.B.,
Grarup, N., Groves, C.J., Hassinen, M., Have, C.T., Herder, C., Holmen, O.L., Hreidarsson, A.B., Humphries,
S.E., Hunter, D.J., Jackson, A.U., Jonsson, A., Jørgensen, M.E., Jørgensen, T., Kao, W.L., Kerrison, N.D.,
Kinnunen, L., Klopp, N., Kong, A., Kovacs, P., Kraft, P., Kravic, J., Langford, C., Leander, K., Liang, L.,
Lichtner, P., Lindgren, C.M., Lindholm, E., Linneberg, A., Liu, C.T., Lobbens, S., Luan, J., Lyssenko, V.,
Männisto, S., McLeod, O., Meyer, J., Mihailov, E., Mirza, G., Mühleisen, T.W., Müller-Nurasyid, M.,
Navarro, C., Nöthen, M.M., Oskolkov, N.N., Owen, K.R., Palli, D., Pechlivanis, S., Peltonen, L., Perry, J.R.,
Platou, C.G., Roden, M., Ruderfer, D., Rybin, D., van der Schouw, Y.T., Sennblad, B., Sigurdsson, G.,
Stancáková, A., Steinbach, G., Storm, P., Strauch, K., Stringham, H.M., Sun, Q., Thorand, B., Tikkanen, E.,
Tönjes, A., Trakalo, J., Tremoli, E., Tuomi, T., Wennauer, R., Wiltshire, S., Wood, A.R., Zeggini, E., Dunham,
I., Birney, E., Pasquali, L., Ferrer, J., Loos, R.J., Dupuis, J., Florez, J.C., Boerwinkle, E., Pankow, J.S., van
Duijn, C.M., Sijbrands, E., Meigs, J.B., Hu, F.B., Thorsteinsdottir, U., Stefansson, K., Lakka, T.A., Rauramaa,
R., Stumvoll, M., Pedersen, N.L., Lind, L., Keinanen-Kiukaanniemi, S.M., Korpi-Hyovalti, E., Saaristo, T.E.,
Saltevo, J., Kuusisto, J., Laakso, M., Metspalu, A., Erbel, R., Jöcke, K.H., Moebus, S., Ripatti, S., Salomaa,
V., Ingelsson, E., Boehm, B.O., Bergman, R.N., Collins, F.S., Mohlke, K.L., Koistinen, H.A., Tuomilehto, J.,
Hveem, K., Njølstad, I., Deloukas, P., Donnelly, P.J., Hattersley, A.T., de Faire, U., Hamsten, A., Illig, T.,
Peters, A., Cauchi, S., Sladek, R., Froguel, P., Hansen, T., Pedersen, O., Morris, A.D., Palmer, C.N.,
Kathiresan, S., Melander, O., Nilsson, P.M., Groop, L.C., Barroso, I., Langenberg, C., Wareham, N.J.,
O'Callaghan, C.A., Gloyn, A.L., Altshuler, D., Boehnke, M., Teslovich, T.M., McCarthy, M.I.°, Morris, A.P.°,
DIAGRAM Consortium: Genetic fine mapping and genomic annotation defines causal mechanisms at type 2
diabetes susceptibility loci. Nat. Genet. 47, 1415-1425 (2015)
page 33 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Gaye, A., Marcon, Y., Isaeva, J., LaFlamme, P., Turner, A., Jones, E.M., Minion, J., Boyd, A.W., Newby,
C.J., Nuotio, M.L., Wilson, R.K., Butters, O., Murtagh, B., Demir, I.E., Doiron, D., Giepmans, L., Wallace,
S.E., Budin-Ljøsne, I., Schmidt, C.O., Boffetta, P., Boniol, M., Bota, M., Carter, K.W., deKlerk, N., Dibben, C.,
Francis, R.W., Hiekkalinna, T., Hveem, K., Kvaløy, K., Millar, S., Perry, I.J., Peters, A., Phillips, C.M.,
Popham, F., Raab, G., Reischl, E., Sheehan, N., Waldenberger, M., Perola, M., van den Heuvel, E.,
Macleod, J., Knoppers, B.M., Stolk, R.P., Fortier, I., Harris, J.R., Woffenbuttel, B.H., Murtagh, M.J., Ferretti,
V., Burton, P.R.°: DataSHIELD: Taking the analysis to the data, not the data to the analysis. Int. J.
Epidemiol. 43, 1929-1944 (2014)
Gharib, S.A.#°, Loth, D.W.#, Soler Artigas, M.#, Birkland, T.P., Wilk, J.B., Wain, L.V., Brody, J.A., Obeidat, M.,
Hancock, D.B., Tang, W., Rawal, R., Boezen, H.M., Imboden, M., Huffman, J.E., Lahousse, L., Alves, A.C.,
Manichaikul, A., Hui, J., Morrison, A.C., Ramasamy, A., Smith, A.V., Gudnason, V., Surakka, I., Vitart, V.,
Evans, D.M., Strachan, D.P., Deary, I.J., Hofman, A., Gläser, S., Wilson, J.F., North, K.E., Zhao, J.H.,
Heckbert, S.R., Jarvis, D.L., Probst-Hensch, N., Schulz, H., Barr, R.G., Jarvelin, M.R., O'Connor, G.T.,
Kähönen, M., Cassano, P.A., Hysi, P.G., Dupuis, J., Hayward, C., Psaty, B.M., Hall, I.P., Parks, W.C., Tobin,
M.D., London, S.J., CHARGE Consortium (Gieger, C., Illig, T.), CHARGE Consortium (Meisinger, C.,
Prokisch, H., Wichmann, H.-E.), SpiroMeta Consortium: Integrative pathway genomics of lung function and
airflow obstruction. Hum. Mol. Genet. 24, 6836-6848 (2015)
#
#
Ghosh, S. , Vivar, J. , Nelson, C.P., Willenborg, C., Segrè, A.V., Maekinen, V., Nikpay, M., Erdmann, J.,
Blankenberg, S., O'Donnell, C., Maerz, W., Laaksonen, R., Stewart, A.F.R., Epstein, S.E., Shah, S.H.,
Granger, C.B., Hazen, S.L., Kathiresan, S., Reilly, M.P., CARDIoGRAM Consortium (Döring, A., Meisinger,
C., Meitinger, T., Peters, A., Wichmann, H.-E.), Yang, X., Quertermous, T., Samani, N.J., Schunkert, H.,
Assimes, T.L., McPherson, R.°: Systems genetics analysis of genome-wide association study reveals novel
associations between key biological processes and coronary artery disease. Arterioscler. Thromb. Vasc.
Biol. 35, 1712-1722 (2015)
Götz, M.°, Sirko, S., Beckers, J., Irmler, M.: Reactive astrocytes as neural stem or progenitor cells: In vivo
lineage, In vitro potential, and genome-wide expression analysis. Glia 63, 1452-1468 (2015)
Goyette, P., Boucher, G., Mallon, D., Ellinghaus, E., Jostins, L., Huang, H., Ripke, S., Gusareva, E.S.,
Annese, V., Hauser, S.L., Oksenberg, J.R., Thomsen, I., Leslie, S., International Inflammatory Bowel
Disease Genetics Consortium (Gieger, C., Winkelmann, J.), Daly, M.J., van Steen, K., Duerr, R.H., Barrett,
J.C., Schumm, L.P., Traherne, J.A., Carrington, M.N., Kosmoliaptsis, V., Karlsen, T.H., Franke, A., Rioux,
J.D.°: High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel
diseases and heterozygous advantage in ulcerative colitis. Nat. Genet. 47, 172-179 (2015)
Grassmann, F., Friedrich, U., Fauser, S., Schick, T., Milenkovic, A., Schulz, H.L., von Strachwitz, C.N.,
Bettecken, T., Lichtner, P., Meitinger, T., Arend, N., Wolf, A., Haritoglou, C., Rudolph, G., Chakravarthy, U.,
Silvestri, G., Mckay, G.J., Freitag-Wolf, S., Krawczak, M., Smith, R., Merriam, J.C., Merriam, J.E., Allikmets,
R.L., Heid, I.M., Weber, B.H.F.°: A candidate gene association study identifies DAPL1 as a female-specific
susceptibility locus for Age-related Macular Degeneration (AMD). Neuromol. Med. 17, 111-120 (2015)
page 34 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Haack, T.B., Staufner, C., Köpke, M., Straub, B.K., Kolker, S., Thiel, C., Freisinger, P., Baric, I., McKiernan,
P.J., Dikow, N., Harting, I., Beisse, F., Burgard, P., Kotzaeridou, U., Kühr, J., Himbert, U., Taylor, R.W.,
Distelmaier, F., Vockley, J., Ghaloul-Gonzalez, L., Zschocke, J., Kremer, L.S., Graf, E., Schwarzmayr, T.,
Bader, D.M., Gagneur, J., Wieland, T., Terrile, C., Strom, T.M., Meitinger, T., Hoffmann, G.F., Prokisch,
H.°: Biallelic mutations in NBAS cause recurrent acute liver failure with onset in infancy. Am. J. Hum. Genet.
97, 163-169 (2015)
Hadchouel, A.#, Wieland, T.#, Griese, M.E.#, Baruffini, E.#, Lorenz-Depiereux, B., Enaud, L., Graf, E.,
Dubus, J.C., Halioui-Louhaïchi, S., Coulomb, A., Delacourt, C., Eckstein, G.N., Zarbock, R., Schwarzmayr,
T., Cartault, F., Meitinger, T., Lodi, T., de Blic, J., Strom, T.M.°: Biallelic mutations of methionyl-tRNA
synthetase cause a specific type of pulmonary alveolar proteinosis prevalent on Réunion Island. Am. J. Hum.
Genet. 96, 826-831 (2015)
Haftenberger, M., Mensink, G.B., Herzog, B., Kluttig, A., Greiser, K.H., Merz, B., Nöthlings, U., Schlesinger,
S., Vogt, S., Thorand, B., Peters, A., Ittermann, T., Völzke, H., Schipf, S., Neamat-Allah, J., Kuhn, T.,
Kaaks, R., Boeing, H., Bachlechner, U., Scheidt-Nave, C., Schienkiewitz, A.°: Changes in body weight and
obesity status in German adults: Results of seven population-based prospective studies. Eur. J. Clin. Nutr.
70, 300-305 (2016) [published online 2015]
Hägg, S., Fall, T., Ploner, A., Mägi, R., Fischer, K., Draisma, H.H., Kals, M., de Vries, P.S., Dehghan, A.,
Willems, S.M., Sarin, A.P., Kristiansson, K., Nuotio, M.L., Havulinna, A.S., de Bruijn, R.F., Ikram, M.A.,
Kuningas, M., Stricker, B.H., Franco, O.H., Benyamin, B., Gieger, C., Hall, A.S., Huikari, V., Jula, A.,
Jarvelin, M.R., Kaakinen, M., Kaprio, J., Kobl, M., Mangino, M., Nelson, C.P., Palotie, A., Samani, N.J.,
Spector, T.D., Strachan, D.P., Tobin, M.D., Whitfield, J.B., Uitterlinden, A.G., Salomaa, V., Syvanen, A.C.,
Kuulasmaa, K., Magnusson, P.K., Esko, T., Hofman, A., de Geus, E.J., Lind, L., Giedraitis, V., Perola, M.,
Evans, A., Ferrieres, J., Virtamo, J., Kee, F., Tregouet, D.A., Arveiler, D., Amouyel, P., Gianfagna, F.,
Brambilla, P., Ripatti, S., van Duijn, C.M., Metspalu, A., Prokopenko, I., McCarthy, M.I., Pedersen, N.L.,
Ingelsson, E.°, ENGAGE Consortium (Döring, A., Nitz, B., Rawal, R., Wichmann, H.-E.): Adiposity as a
cause of cardiovascular disease: A Mendelian randomization study. Int. J. Epidemiol. 44, 578-586 (2015)
Halama, A., Horsch, M., Kastenmüller, G., Möller, G., Kumar, P., Prehn, C., Laumen, H., Hauner, H.,
Hrabě de Angelis, M., Beckers, J., Suhre, K., Adamski, J.°: Metabolic switch during adipogenesis: From
branched chain amino acid catabolism to lipid synthesis. Arch. Biochem. Biophys. 589, 93-107 (2015)
Hampel, R., Peters, A., Beelen, R., Brunekreef, B., Cyrys, J., de Faire, U., de Hoogh, K., Fuks, K.,
Hoffmann, B., Hüls, A., Imboden, M., Jedynska, A., Kooter, I.M., Koenig, W., Künzli, N., Leander, K.,
Magnusson, P., Männisto, S., Penell, J., Pershagen, G., Phuleria, H., Probst-Hensch, N., Pundt, N.,
Schaffner, E., Schikowski, T., Sugiri, D., Tiittanen, P., Tsai, M.Y., Wang, M., Wolf, K., Lanki, T.: Long-term
effects of elemental composition of particulate matter on inflammatory blood markers in European cohorts.
Environ. Int. 82, 76-84 (2015)
page 35 of 213
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Hansen, J.S., Zhao, X., Irmler, M., Liu, X., Hoene, M., Scheler, M., Li, Y., Beckers, J., Hrabě de Angelis,
M., Häring, H.-U., Pedersen, B.K., Lehmann, R., Xu, G.°, Plomgaard, P.°, Weigert, C.°: Type 2 diabetes
alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and
recovery. Diabetologia 58, 1845-1854 (2015)
Häring, H.-U., Hrabě de Angelis, M., Joost, H.G., Roden, M., Schürmann, A., Solimena, M.: 5 Jahre
erfolgreiche translationale Forschung - Deutsches Zentrum für Diabetesforschung. Diabetes akt. 13, 58-62
(2015)
Helbig, A.K.°, Stöckl, D., Heier, M., Ladwig, K.-H., Meisinger, C.: Symptoms of insomnia and sleep
duration and their association with incident strokes: Findings from the population-based MONICA/KORA
Augsburg cohort study. PLoS ONE 10:e0134480 (2015)
Hellfritsch, J., Kirsch, J., Schneider, M., Fluege, C., Wortmann, M., Frijhoff, J., Dagnell, M., Fey, T.,
Esposito, I., Kölle, P., Pogoda, K., Ingold, I., Angeli, J.P., Kuhlencordt, P., Östman, A., Pohl, U., Beck, H.°,
Conrad, M.°: Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits
tumor growth and tumor-derived angiogenesis. Antioxid. Redox Signal. 22, 938-950 (2015)
#
#
Helmbrecht, M.S. , Soellner, H. , Castiblanco-Urbina, M.A., Winzeck, S., Sundermeier, J., Theis, F.J.,
Fouad, K., Huber, A.B.°: A critical period for postnatal adaptive plasticity in a model of motor axon miswiring.
PLoS ONE 10:e0123643 (2015)
Helmbrecht, M.S.°, Soellner, H., Truckenbrodt, A.M., Sundermeier, J., Cohrs, C., Hans, W., Hrabě de
Angelis, M., Feuchtinger, A., Aichler, M., Fouad, K., Huber, A.B.°: Loss of Npn1 from motor neurons
causes postnatal deficits independent from Sema3A signaling. Dev. Biol. 399, 2-14 (2015)
Hempel, M., Cremer, K., Ockeloen, C.W., Lichtenbelt, K.D., Herkert, J.C., Denecke, J., Haack, T.B., Zink,
A.M., Becker, J., Wohlleber, E., Johannsen, J., Alhaddad, B., Pfundt, R., Fuchs, S., Wieczorek, D., Strom,
T.M., van Gassen, K.L., Kleefstra, T., Kubisch, C., Engels, H., Lessel, D.°: De novo mutations in CHAMP1
cause intellectual disability with severe speech impairment. Am. J. Hum. Genet. 97, 493-500 (2015)
Herder, C.°, Ouwens, D.M., Carstensen, M., Kowall, B., Huth, C., Meisinger, C., Rathmann, W., Roden, M.,
Thorand, B.: Adiponectin may mediate the association between omentin, circulating lipids and insulin
sensitivity: Results from the KORA F4 study. Eur. J. Endocrinol. 172, 423-432 (2015)
Herder, C.°, Bongaerts, B.W., Ouwens, D.M., Rathmann, W., Heier, M., Carstensen-Kirberg, M., Koenig, W.,
Thorand, B., Roden, M., Meisinger, C., Ziegler, D., KORA Study Group (Gieger, C., Grallert, H., Heinrich,
J., Holle, R., Leidl, R., Peters, A., Strauch, K.): Low serum omentin levels in the elderly population with
type 2 diabetes and polyneuropathy. Diabet. Med. 32, 1479-1483 (2015)
Hernesniemi, J.A.°, Lyytikäinen, L.P., Oksala, N., Seppälä, I., Kleber, M.E., Mononen, N., Marz, W.,
Mikkelsson, J., Pessi, T., Louhelainen, A.M., Martiskainen, M., Nikus, K., Klopp, N., Waldenberger, M., Illig,
T., Kähönen, M., Laaksonen, R., Karhunen, P.J., Lehtimäki, T.: Predicting sudden cardiac death using
common genetic risk variants for coronary artery disease. Eur. Heart J. 36, 1669-1675 (2015)
page 36 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Hetterich, H.°, Bayerl, C., Peters, A., Heier, M., Linkohr, B., Meisinger, C., Auweter, S., Kannengießer,
S.A., Kramer, H., Ertl-Wagner, B., Bamberg, F.°: Feasibility of a three-step magnetic resonance imaging
approach for the assessment of hepatic steatosis in an asymptomatic study population. Eur. Radiol., DOI:
10.1007/s00330-015-3966-y (2015)
Hirn, S., Haberl, N., Loza, K., Epple, M., Kreyling, W.G., Rothen-Rutishauser, B., Rehberg, M., Krombach,
F.°: Proinflammatory and cytotoxic response to nanoparticles in precision-cut lung slices. Beilstein J.
Nanotechnol. 5, 2440-2449 (2014)
Höhne, B.°, Pabst, A., Hannemann, T.-V., Kraus, L.: Patterns of concurrent alcohol, tobacco, and cannabis
use in Germany: Prevalence and correlates. Drugs Educ. Prev. Policy 21, 102-109 (2014)
Holm, A.T., Wulf-Johansson, H., Hvidtsen, S., Jorgensen, P.T., Schlosser, A., Pilecki, B., Ormhoj, M.,
Moeller, J.B., Johannsen, C., Baun, C., Andersen, T., Schneider, J.P., Hegermann, J., Ochs, M., Götz, A.A.,
Schulz, H., Hrabě de Angelis, M., Vestbo, J., Holmskov, U., Sorensen, G.L.°: Characterization of
spontaneous air space enlargement in mice lacking microfibrillar-associated protein 4. Am. J. Physiol. Lung
Cell Mol. Physiol. 308, L1114-L1124 (2015)
Holzerova, E., Danhauser, K., Haack, T.B., Kremer, L.S., Melcher, M., Ingold, I., Kobayashi, S., Terrile,
C., Wolf, P., Schaper, J., Mayatepek, E., Baertling, F., Friedmann Angeli, J.P., Conrad, M., Strom, T.M.,
Meitinger, T., Prokisch, H.°, Distelmaier, F.: Human thioredoxin 2 deficiency impairs mitochondrial redox
homeostasis and causes early-onset neurodegeneration. Brain 139, 346-354 (2016) [published online 2015]
Holzerova, E., Prokisch, H.°: Mitochondria: Much ado about nothing? How dangerous is reactive oxygen
species production? Int. J. Biochem. Cell Biol. 63, 16-20 (2015)
Homuth, G.°, Wahl, S., Mueller, C., Schurmann, C., Maeder, U., Blankenberg, S., Carstensen, M., Doerr, M.,
Endlich, K., Englbrecht, C., Felix, S.B., Gieger, C., Grallert, H., Herder, C., Illig, T., Kruppa, J., Marzi, C.S.,
Mayerle, J., Meitinger, T., Metspalu, A., Nauck, M., Peters, A., Rathmann, W., Reinmaa, E., Rettig, R.,
Roden, M., Schillert, A., Schramm, K., Steil, L., Strauch, K., Teumer, A., Voelzke, H., Wallaschofski, H.,
Wild, P.S., Ziegler, A., Voelker, U., Prokisch, H., Zeller, T.: Extensive alterations of the whole-blood
transcriptome are associated with body mass index: Results of an mRNA profiling study involving two large
population-based cohorts. BMC Med. Genomics 8:65 (2015)
Hoover, M.D.°, Myers, D.S., Cash, L.J., Guilmette, R.A., Kreyling, W.G., Oberdörster, G., Smith, R.,
Cassata, J.R., Boecker, B.B., Grissom, M.P.: Application of an informatics-based decision-making framework
and process to the assessment of radiation safety in nanotechnology. Health Phys. 108, 179-194 (2015)
page 37 of 213
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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#
#
Horikoshi, M. °, Mägi, R. , van de Bunt, M., Surakka, I., Sarin, A.P., Mahajan, A., Marullo, L., Thorleifsson,
G., Hägg, S., Hottenga, J.J., Ladenvall, C., Ried, J.S., Winkler, T.W., Willems, S.M., Pervjakova, N., Esko,
T., Beekman, M., Nelson, C.P., Willenborg, C., Wiltshire, S., Ferreira, T., Fernández, J., Gaulton, K.J.,
Steinthorsdottir, V., Hamsten, A., Magnusson, P.K., Willemsen, G., Milaneschi, Y., Robertson, N.R., Groves,
C.J., Bennett, A.J., Lehtimäki, T., Viikari, J.S., Rung, J., Lyssenko, V., Perola, M., Heid, I.M., Herder, C.,
Grallert, H., Müller-Nurasyid, M., Roden, M., Hyppönen, E., Isaacs, A., van Leeuwen, E.M., Karssen, L.C.,
Mihailov, E., Houwing-Duistermaat, J.J., de Craen, A.J., Deelen, J., Havulinna, A.S., Blades, M.,
Hengstenberg, C., Erdmann, J., Schunkert, H., Kaprio, J., Tobin, M.D., Samani, N.J., Lind, L., Salomaa, V.,
Lindgren, C.M., Slagboom, P.E., Metspalu, A., van Duijn, C.M., Eriksson, J.G., Peters, A., Gieger, C., Jula,
A., Groop, L., Raitakari, O.T., Power, C., Penninx, B.W., de Geus, E., Smit, J.H., Boomsma, D.I., Pedersen,
N.L., Ingelsson, E., Thorsteinsdottir, U., Stefansson, K., Ripatti, S., Prokopenko, I., McCarthy, M.I., Morris,
A.P., ENGAGE Consortium (Döring, A., Nitz, B., Rawal, R., Wichmann, H.-E.): Discovery and fine-mapping
of glycaemic and obesity-related trait loci using high-density imputation. PLoS Genet. 11:e1005230 (2015)
Horsch, M.#, Aguilar-Pimentel, J.A.#, Bönisch, C., Côme, C., Kolster-Fog, C., Jensen, K.T., Lund, A.H.,
Lee, I., Grossman, L.I., Sinkler, C., Hüttemann, M., Bohn, E., Fuchs, H., Ollert, M., Gailus-Durner, V.,
Hrabě de Angelis, M., Beckers, J.°: Cox4i2, Ifit2, and Prdm11 mutant mice: Effective selection of genes
predisposing to an altered airway inflammatory response from a large compendium of mutant mouse lines.
PLoS ONE 10:e0134503 (2015)
page 38 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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Hrabě de Angelis, M. , Nicholson, G. , Selloum, M. , White, J.K. , Morgan, H. , Ramirez-Solis, R. , Sorg,
#
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#
#
T. , Wells, S. , Fuchs, H. , Fray, M. , Adams, D.J., Adams, N.C., Adler, T., Aguilar-Pimentel, J.A.,
Ali-Hadji, D., Amann, G., André, P., Atkins, S., Auburtin, A., Ayadi, A., Becker, J., Becker, L., Bedu, E.,
Bekeredjian, R., Birling, M.C., Blake, A., Bottomley, J., Bowl, M.R., Brault, V., Busch, D.H., Bussell, J.N.,
Calzada-Wack, J., Cater, H., Champy, M.F., Charles, P., Chevalier, C., Chiani, F., Codner, G.F., Combe, R.,
Cox, R.D., Dalloneau, E., Dierich, A., di Fenza, A., Doe, B., Duchon, A., Eickelberg, O., Esapa, C.T., Fertak,
L.E., Feigel, T., Emelyanova, I., Estabel, J., Favor, J., Flenniken, A.M., Gambadoro, A., Garrett, L., Gates,
H., Gerdin, A.K., Gkoutos, G.V., Greenaway, S., Glasl, L., Goetz, P., da Cruz, I.G., Götz, A., Graw, J.,
Guimond, A., Hans, W., Hicks, G., Hölter, S.M., Höfler, H., Hancock, J.M., Hoehndorf, R., Hough, T.,
Houghton, R., Hurt, A., Ivandic, B., Jacobs, H., Jacquot, S., Jones, N., Karp, N.A., Katus, H.A., Kitchen, S.,
Klein-Rodewald, T., Klingenspor, M., Klopstock, T., Lalanne, V., Leblanc, S., Lengger, C., le Marchand,
E., Ludwig, T., Lux, A., McKerlie, C., Maier, H., Mandel, J.L., Marschall, S., Mark, M., Melvin, D.G.,
Meziane, H., Micklich, K., Mittelhauser, C., Monassier, L., Moulaert, D., Müller, S., Naton, B., Neff, F.,
Nolan, P.M., Nutter, L.M., Ollert, M., Pavlovic, G., Pellegata, N.S., Peter, E., Petit-Demoulière, B., Pickard,
A., Podrini, C., Potter, P., Pouilly, L., Puk, O., Richardson, D., Rousseau, S., Quintanilla-Fend, L., Quwailid,
M.M., Rácz, I., Rathkolb, B., Riet, F., Rossant, J., Roux, M., Rozman, J., Ryder, E., Salisbury, J., Santos,
L., Schäble, K.-H., Schiller, E., Schrewe, A., Schulz, H., Steinkamp, R., Simon, M., Stewart, M., Stöger,
C., Stöger, T., Sun, M., Sunter, D., Teboul, L., Tilly, I., Tocchini-Valentini, G.P., Tost, M., Treise, I.,
Vasseur, L., Velot, E., Vogt Weisenhorn, D.M., Wagner, C., Walling, A., Wattenhofer-Donze, M., Weber, B.,
Wendling, O., Westerberg, H., Willershäuser, M., Wolf, E., Wolter, A., Wood, J., Wurst, W., Yildirim, A.Ö.,
#
#
#
#
Zeh, R., Zimmer, A., Zimprich, A., Holmes, C. , Steel, K.P. , Herault, Y. , Gailus-Durner, V. , Mallon,
#
#
A.M. , Brown, S.D. °: Analysis of mammalian gene function through broad-based phenotypic screens across
a consortium of mouse clinics. Nat. Genet. 47, 969-978 (2015)
Huan, T.#, Esko, T.#, Peters, M.J.#, Pilling, L.C.#, Schramm, K.#, Schurmann, C.#, Chen, B.H., Liu, C.,
Joehanes, R., Johnson, A.D., Yao, C., Ying, S.X., Courchesne, P., Milani, L., Raghavachari, N., Wang, R.,
Liu, P., Reinmaa, E., Dehghan, A., Hofman, A., Uitterlinden, A.G., Hernandez, D.G., Bandinelli, S., Singleton,
A., Melzer, D., Metspalu, A., Carstensen, M., Grallert, H., Herder, C., Meitinger, T., Peters, A., Roden, M.,
Waldenberger, M., Dörr, M., Felix, S.B., Zeller, T., ICBP Consortium (Levy, D.°), Vasan, R.S., O'Donnell,
C.J., Munson, P.J., Yang, X.°, Prokisch, H.°, Völker, U.°, van Meurs, J.B.°, Ferrucci, L.°: A meta-analysis of
gene expression signatures of blood pressure and hypertension. PLoS Genet. 11:e1005035 (2015)
Huemer, M.°, Karall, D., Schossig, A., Abdenur, J.E., Al Jasmi, F., Biagosch, C.A., Distelmaier, F.,
Freisinger, P., Graham, B.H., Haack, T.B., Hauser, N., Hertecant, J., Ebrahimi-Fakhari, D., Konstantopoulou,
V., Leydiker, K., Lourenco, C.M., Scholl-Bürgi, S., Wilichowski, E., Wolf, N.I., Wortmann, S.B., Taylor, R.W.,
Mayr, J.A., Bonnen, P.E., Sperl, W., Prokisch, H., McFarland, R.: Clinical, morphological, biochemical,
imaging and outcome parameters in 21 individuals with mitochondrial maintenance defect related to FBXL4
mutations. J. Inherit. Metab. Dis. 38, 905-914 (2015)
page 39 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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Huffman, J.E., Albrecht, E., Teumer, A., Mangino, M., Kapur, K., Johnson, T., Kutalik, Z., Pirastu, N., Pistis,
G., Lopez, L.M., Haller, T., Salo, P., Goel, A., Li, M., Tanaka, T., Dehghan, A., Ruggiero, D., Malerba, G.,
Smith, A.V., Nolte, I.M., Portas, L., Phipps-Green, A., Boteva, L., Navarro, P., Johansson, A., Hicks, A.A.,
Polasek, O., Esko, T., Peden, J.F., Harris, S.E., Murgia, F., Wild, S.H., Tenesa, A., Tin, A., Mihailov, E.,
Grotevendt, A., Gislason, G.K., Coresh, J., D'Adamo, P., Ulivi, S., Vollenweider, P., Waeber, G., Campbell,
S., Kolcic, I., Fisher, K., Viigimaa, M., Metter, J.E., Masciullo, C., Trabetti, E., Bombieri, C., Sorice, R.,
Döring, A., Reischl, E., Strauch, K., Hofman, A., Uitterlinden, A.G., Waldenberger, M., Wichmann, H.-E.,
Davies, G., Gow, A.J., Dalbeth, N., Stamp, L., Smit, J.H., Kirin, M., Nagaraja, R., Nauck, M., Schurmann, C.,
Budde, K., Farrington, S.M., Theodoratou, E., Jula, A., Salomaa, V., Sala, C., Hengstenberg, C., Burnier, M.,
Mägi, R., Klopp, N., Kloiber, S., Schipf, S., Ripatti, S., Cabras, S., Soranzo, N., Homuth, G., Nutile, T.,
Munroe, P.B., Hastie, N., Campbell, H., Rudan, I., Cabrera, C., Haley, C., Franco, O.H., Merriman, T.R.,
Gudnason, V., Pirastu, M., Penninx, B.W., Snieder, H., Metspalu, A., Ciullo, M., Pramstaller, P.P., van Duijn,
C.M., Ferrucci, L., Gambaro, G., Deary, I.J., Dunlop, M.G., Wilson, J.F., Gasparini, P., Gyllensten, U.,
Spector, T.D., Wright, A.F., Hayward, C., Watkins, H., Perola, M., Bochud, M., Kao, W.H., Caulfield, M.,
Toniolo, D., Völzke, H., Gieger, C., Köttgen, A., Vitart, V.°: Modulation of genetic associations with serum
urate levels by body-mass-index in humans. PLoS ONE 10:e0119752 (2015)
Huffman, J.E., de Vries, P.S., Morrison, A.C., Sabater-Lleal, M., Kacprowski, T., Auer, P.L., Brody, J.A.,
Chasman, D.I., Chen, M.H., Guo, X., Lin, L.A., Marioni, R.E., Müller-Nurasyid, M., Yanek, L.R., Pankratz,
N., Grove, M.L., de Maat, M.P.M., Cushman, M., Wiggins, K.L., Qi, L., Sennblad, B., Harris, S.E., Polasek,
O., Riess, H., Rivadeneira, F., Rose, L.M., Goel, A., Taylor, K.D., Teumer, A., Uitterlinden, A.G., Vaidya, D.,
Yao, J., Tang, W., Levy, D., Waldenberger, M., Becker, D.M., Folsom, A.R., Giulianini, F., Greinacher, A.,
Hofman, A., Huang, C.C., Kooperberg, C., Silveira, A., Starr, J.M., Strauch, K., Strawbridge, R.J., Wright,
A.F., McKnight, B., Franco, O.H., Zakai, N., Mathias, R.A., Psaty, B.M., Ridker, P.M., Tofler, G.H., Völker, U.,
Watkins, H., Fornage, M., Hamsten, A., Deary, I.J., Boerwinkle, E., Koenig, W., Rotter, J.I., Hayward, C.,
Dehghan, A., Reiner, A.P., O'Donnell, C.J., Smith, N.L.°: Rare and low-frequency variants and their
association with plasma levels of fibrinogen, FVII, FVIII, and vWF. Blood 126, e19-e29 (2015)
Huth, C., Beuerle, S., Zierer, A., Heier, M., Herder, C., Kaiser, T., Koenig, W., Kronenberg, F., Oexle, K.,
Rathmann, W., Roden, M., Schwab, S., Seissler, J., Stöckl, D., Meisinger, C., Peters, A., Thorand, B.°:
Biomarkers of iron metabolism are independently associated with impaired glucose metabolism and type 2
diabetes: The KORA F4 Study. Eur. J. Endocrinol. 173, 643-653 (2015)
Ingold, I., Aichler, M., Yefremova, E., Roveri, A., Buday, K., Doll, S., Tasdemir, A., Hoffard, N., Wurst,
W., Walch, A.K., Ursini, F., Friedmann Angeli, J.P., Conrad, M.°: Expression of a catalytically inactive
mutant form of Glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility. J. Biol.
Chem. 290, 14668-14678 (2015)
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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Interleukin 1 Genetics Consortium, Freitag, D.F., Butterworth, A.S., Willeit, P., Howson, J.M.M., Burgess,
S.L., Kaptoge, S.K., Young, R., Ho, W.K., Wood, A.M., Sweeting, M., Spackman, S., Staley, J.R., Ramond,
A., Harshfield, E., Nielsen, S.F., Grande, P., Lange, L.A., Bown, M., Jones, G.T., Scott, R.A.H., Bevan, S.N.,
Porcu, E., Thorleifsson, G., Zeng, L.M., Kessler, T., Nikpay, M., Do, R., Zhang, W., Hopewell, J.C., Kleber,
M.E., Delgado, G.E., Nelson, C.P., Goel, A., Bis, J.C.M., Dehghan, A.J., Ligthart, S., Smith, A.V., Qu, L., van
'T Hof, F., de Bakker, P.I.W., Baas, A.F., van Rij, A.M., Tromp, G., Kuivaniemi, H., Ritchie, M.D., Verma,
S.S., Crawford, D.C., Malinowski, J., de Andrade, M., Kullo, I.J., Peissig, P.L., McCarty, C.A., Bottinger, E.P.,
Gottesman, O., Crosslin, D.R., Carrell, D.S., Rasmussen-Torvik, L.J., Pacheco, J.A., Huang, J., Timpson,
N.J., Kettunen, J.A., Ala-Korpela, M., Mitchell, G.F., Parsa, A., Wilkinson, I.B., Gorski, M., Li, Y.,
Franceschini, N.C., Keller, M.F., Ganesh, S.K., Langefeld, C.D., Bruijn, L., Brown, M.A., Evans, D.M.D.,
Baltic, S., Ferreira, M.A.R., Baurecht, H.J., Weidinger, S., Franke, A., Lubitz, S.A., Müller-Nurasyid, M.,
Felix, J.F., Smith, N.L., Sudman, M., Thompson, S.D., Zeggini, E., Panoutsopoulou, K., Nalls, M.A.,
Singleton, A.B., Polychronakos, C., Bradfield, J.P., Hakonarson, H.H., Easton, D.F., Thompson, D.J.,
Tomlinson, I.P.M., Dunlop, M.G., Hemminki, K.L., Morgan, G., Eisen, T., Goldschmidt, H.P., Allan, J.M.,
Henrion, M., Whiffin, N., Wang, Y., Chubb, D., Iles, M.M., Bishop, D.T., Law, M.H., Hayward, N.K., Luo, Y.,
Nejentsev, S., Barbalic, M., Crossman, D.C., Sanna, S., Soranzo, N., Markus, H.S., Wareham, N.J., Rader,
D.J., Reilly, M.P., Assimes, T.L., Harris, T.B., Hofman, A., Franco, O.H., Gudnason, V.G., Tracy, R.P., Psaty,
B.M., Farrall, M.J., Watkins, H., Hall, A.S., Samani, N.J., Marz, W., Clarke, R., Collins, R.E., Kooner, J.S.,
Chambers, J.C., Kathiresan, S., McPherson, R., Erdmann, J., Kastrati, A., Schunkert, H., Stefansson, K.,
Thorsteinsdottir, U., Walston, J.D., Tybjærg-Hansen, A., Alam, D.S., Al Shafi Majumder, A., Angelantonio,
E.D., Chowdhury, R., Nordestgaard, B.G., Saleheen, D., Thompson, S.G., Danesh, J., Houlston, R.S.°:
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A mendelian
randomisation analysis. Lancet Diabet. Endocrinol. 3, 243-253 (2015)
Jansen, H., Loley, C., Lieb, W., Pencina, M.J., Nelson, C.P., Kathiresan, S., Peloso, G.M., Voight, B.F.,
Reilly, M.P., Assimes, T.L., Boerwinkle, E., Hengstenberg, C., Laaksonen, R., McPherson, R., Roberts, R.,
Thorsteinsdottir, U., Peters, A., Gieger, C., Rawal, R., CARDIoGRAM Consortium (Döring, A., Meisinger,
C., Schunkert, H.°, Meitinger, T.), Thompson, J.R., König, I.R., Vasan, R.S., Erdmann, J., Samani, N.J.:
Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk.
Atherosclerosis 241, 419-426 (2015)
Jansen, I.E., Bras, J.M., Lesage, S., Schulte, C., Gibbs, J.R., Nalls, M.A., Brice, A., Wood, N.W., Morris,
H.R., Hardy, J.A., Singleton, A.B., Gasser, T., Heutink, P., Sharma, M.°, International Parkinson's Disease
Genomics Consortium (IPDGC) (Illig, T., Lichtner, P.): CHCHD2 and Parkinson's disease. Lancet Neurol.
14, 678-679 (2015)
Jiang, Y.°, Sigmund, F., Reber, J., Dean-Ben, X.L., Glasl, S., Kneipp, M., Estrada, H., Razansky, D.,
Ntziachristos, V., Westmeyer, G.G.: Violacein as a genetically-controlled, enzymatically amplified and
photobleaching-resistant chromophore for optoacoustic bacterial imaging. Sci. Rep. 5:11048 (2015)
Jochim, A., Zech, M., Gora-Stahlberg, G., Winkelmann, J., Haslinger, B.°: The clinical phenotype of
early-onset isolated dystonia caused by recessive COL6A3 mutations (DYT27). Mov. Disord., DOI:
10.1002/mds.26501 (2015)
page 41 of 213
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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Joshi, P.K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., Jackson, A.U., Schurmann, C., Smith,
A.V., Zhang, W., Okada, Y., Stancáková, A., Faul, J.D., Zhao, W., Bartz, T.M., Concas, M.P., Franceschini,
N., Enroth, S., Vitart, V., Trompet, S., Guo, X., Chasman, D.I., O'Connel, J.R., Corre, T., Nongmaithem, S.S.,
Chen, Y., Mangino, M., Ruggiero, D., Traglia, M., Farmaki, A.E., Kacprowski, T., Bjonnes, A., van der Spek,
A., Wu, Y., Giri, A.K., Yanek, L.R., Wang, L., Hofer, E., Rietveld, C.A., McLeod, O., Cornelis, M.C., Pattaro,
C., Verweij, N., Baumbach, C., Abdellaoui, A., Warren, H.R., Vuckovic, D., Mei, H., Bouchard, C., Perry,
J.R., Cappellani, S., Mirza, S.S., Benton, M.C., Broeckel, U., Medland, S.E., Lind, P.A., Malerba, G., Drong,
A., Yengo, L., Bielak, L.F., Zhi, D., van der Most, P.J., Shriner, D., Mägi, R., Hemani, G., Karaderi, T., Wang,
Z., Liu, T., Demuth, I., Zhao, J.H., Meng, W., Lataniotis, L., van der Laan, S.W., Bradfield, J.P., Wood, A.R.,
Bonnefond, A., Ahluwalia, T.S., Hall, L.M., Salvi, E., Yazar, S., Carstensen, L., de Haan, H.G., Abney, M.,
Afzal, U., Allison, M.A., Amin, N., Asselbergs, F.W., Bakker, S.J., Barr, R.G., Baumeister, S.E., Benjamin,
D.J., Bergmann, S., Boerwinkle, E., Bottinger, E.P., Campbell, A., Chakravarti, A., Chan, Y., Chanock, S.J.,
Chen, C., Chen, Y.I., Collins, F.S., Connell, J., Correa, A., Cupples, L.A., Smith, G.D., Davies, G., Dörr, M.,
Ehret, G., Ellis, S.B., Feenstra, B., Feitosa, M.F., Ford, I., Fox, C.S., Frayling, T.M., Friedrich, N., Geller, F.,
Scotland, G., Gillham-Nasenya, I., Gottesman, O., Graff, M., Grodstein, F., Gu, C., Haley, C., Hammond,
C.J., Harris, S.E., Harris, T.B., Hastie, N.D., Heard-Costa, N.L., Heikkilä, K., Hocking, L.J., Homuth, G.,
Hottenga, J.J., Huang, J., Huffman, J.E., Hysi, P.G., Ikram, M.A., Ingelsson, E., Joensuu, A., Johansson, Å,
Jousilahti, P., Jukema, J.W., Kähönen, M., Kamatani, Y., Kanoni, S., Kerr, S.M., Khan, N.M., Koellinger,
P.D., Koistinen, H.A., Kooner, M.K., Kubo, M., Kuusisto, J., Lahti, J., Launer, L.J., Lea, R.A., Lehne, B.,
Lehtimäki, T., Liewald, D.C., Lind, L., Loh, M., Lokki, M.L., London, S.J., Loomis, S.J., Loukola, A., Lu, Y.,
Lumley, T., Lundqvist, A., Männisto, S., Marques-Vidal, P., Masciullo, C., Matchan, A., Mathias, R.A.,
Matsuda, K., Meigs, J.B., Meisinger, C., Meitinger, T., Menni, C., Mentch, F.D., Mihailov, E., Milani, L.,
Montasser, M.E., Montgomery, G.W., Morrison, A., Myers, R.H., Nadukuru, R., Navarro, P., Nelis, M.,
Nieminen, M.S., Nolte, I.M., O'Connor, G.T., Ogunniyi, A., Padmanabhan, S., Palmas, W.R., Pankow, J.S.,
Patarcic, I., Pavani, F., Peyser, P.A., Pietiläinen, K.H., Poulter, N., Prokopenko, I., Ralhan, S., Redmond, P.,
Rich, S.S., Rissanen, H., Robino, A., Rose, L.M., Rose, R.M., Sala, C., Salako, B., Salomaa, V., Sarin, A.P.,
Saxena, R., Schmidt, H., Scott, L.J., Scott, W.R., Sennblad, B., Seshadri, S., Sever, P., Shrestha, S., Smith,
B.H., Smith, J.A., Soranzo, N., Sotoodehnia, N., Southam, L., Stanton, A.V., Stathopoulou, M.G., Strauch,
K., Strawbridge, R.J., Suderman, M.J., Tandon, N., Tang, S.T., Taylor, K.D., Tayo, B.O., Töglhofer, A.M.,
Tomaszewski, M., Tsernikova, N., Tuomilehto, J., Uitterlinden, A.G., Vaidya, D., van Hylckama Vlieg, A., van
Setten, J., Vasankari, T., Vedantam, S., Vlachopoulou, E., Vozzi, D., Vuoksimaa, E., Waldenberger, M.,
Ware, E.B., Wentworth-Shields, W., Whitfield, J.B., Wild, S., Willemsen, G., Yajnik, C.S., Yao, J., Zaza, G.,
Zhu, X., Salem, R.M., Melbye, M., Bisgaard, H., Samani, N.J., Cusi, D., Mackey, D.A., Cooper, R.S.,
Froguel, P., Pasterkamp, G., Grant, S.F., Hakonarson, H., Ferrucci, L., Scott, R.A., Morris, A.D., Palmer,
C.N., Dedoussis, G., Deloukas, P., Bertram, L., Lindenberger, U., Berndt, S.I., Lindgren, C.M., Timpson,
N.J., Tönjes, A., Munroe, P.B., Sørensen, T.I., Rotimi, C.N., Arnett, D.K., Oldehinkel, A.J., Kardia, S.L.,
Balkau, B., Gambaro, G., Morris, A.P., Eriksson, J.G., Wright, M.J., Martin, N.G., Hunt, S.C., Starr, J.M.,
Deary, I.J., Griffiths, L.R., Tiemeier, H., Pirastu, N., Kaprio, J., Wareham, N.J., Perusse, L., Wilson, J.G.,
Girotto, G., Caulfield, M.J., Raitakari, O., Boomsma, D.I., Gieger, C., van der Harst, P., Hicks, A.A., Kraft, P.,
Sinisalo, J., Knekt, P., Johannesson, M., Magnusson, P.K., Hamsten, A., Schmidt, R., Borecki, I.B.,
Vartiainen, E., Becker, D.M., Bharadwaj, D., Mohlke, K.L., Boehnke, M., van Duijn, C.M., Sanghera, D.K.,
Teumer, A., Zeggini, E., Metspalu, A., Gasparini, P., Ulivi, S., Ober, C., Toniolo, D., Rudan, I., Porteous, D.J.,
page 42 of 213
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Ciullo, M., Spector, T.D., Hayward, C., Dupuis, J., Loos, R.J., Wright, A.F., Chandak, G.R., Vollenweider, P.,
Shuldiner, A.R., Ridker, P.M., Rotter, J.I., Sattar, N., Gyllensten, U., North, K.E., Pirastu, M., Psaty, B.M.,
Weir, D.R., Laakso, M., Gudnason, V., Takahashi, A., Chambers, J.C., Kooner, J.S., Strachan, D.P.,
Campbell, H., Hirschhorn, J.N., Perola, M., Polasek, O., Wilson, J.F.°: Directional dominance on stature and
cognition in diverse human populations. Nature 523, 459-462 (2015)
Jun, G., Ibrahim-Verbaas, C.A., Vronskaya, M., Lambert, J.C., Chung, J., Naj, A.C., Kunkle, B.W., Wang,
L.S., Bis, J.C., Bellenguez, C., Harold, D., Lunetta, K.L., DeStefano, A.L., Grenier-Boley, B., Sims, R.,
Beecham, G.W., Smith, A.V., Chouraki, V., Hamilton-Nelson, K.L., Ikram, M.A., Fievet, N., Denning, N.,
Martin, E.R., Schmidt, H., Kamatani, Y., Dunstan, M.L., Valladares, O., Laza, A.R., Zelenika, D., Ramirez, A.,
Foroud, T.M., Choi, S.H., Boland, A., Becker, T., Kukull, W.A., van der Lee, S.J., Pasquier, F., Cruchaga, C.,
Beekly, D., Fitzpatrick, A.L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett,
D.A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J.D., Lopez, O.L., Deramecourt, V., Fox, N.C., Cantwell, L.B.,
Tárraga, L., Dufouil, C., Hardy, J., Crane, P.K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley,
T.H. J.r., Letenneur, L., Brayne, C., Maier, W., de Jager, P.L., Emilsson, V., Dartigues, J.F., Hampel, H.,
Kamboh, M.I., de Bruijn, R.F., Tzourio, C., Pastor, P., Larson, E.B., Rotter, J.I., O'Donovan, M.C., Montine,
T.J., Nalls, M.A., Mead, S., Reiman, E.M., Jonsson, P.V., Holmes, C., St. George-Hyslop, P.H., Boada, M.,
Passmore, P.A., Wendland, J.R., Schmidt, R., Morgan, K., Winslow, A.R., Powell, J.F., Carasquillo, M.,
Younkin, S.G., Jakobsdottir, J., Kauwe, J.S., Wilhelmsen, K.C., Rujescu, D., Nöthen, M.M., Hofman, A.,
Jones, L., IGAP Consortium (Klopp, N., Wichmann, H.-E.), Haines, J.L., Psaty, B.M., van Broeckhoven, C.,
Holmans, P., Launer, L.J., Mayeux, R., Lathrop, M., Goate, A.M., Escott-Price, V., Seshadri, S.,
Pericak-Vance, M.A., Amouyel, P., Williams, J., van Duijn, C.M., Schellenberg, G.D., Farrer, L.A.°: A novel
Alzheimer disease locus located near the gene encoding tau protein. Mol. Psychiatry 21, 108–117 (2016)
[published online 2015]
Kaess, B.M., Preis, S.R., Lieb, W., Beiser, A.S., Yang, Q., Chen, T.C., Hengstenberg, C., Erdmann, J.,
Schunkert, H., Seshadri, S., Vasan, R.S., CARDIoGRAM Consortium (Döring, A., Meisinger, C., Meitinger,
T., Peters, A., Wichmann, H.-E.): Circulating brain-derived neurotrophic factor concentrations and the risk of
cardiovascular disease in the community. J. Am. Heart Assoc. 4:e001544 (2015)
Kagan, V.E.°, Tyurina, Y.Y., Tyurin, V.A., Mohammadyani, D., Friedmann Angeli, J.P., Baranov, S.V.,
Klein-Seetharaman, J., Friedlander, R.M., Mallampalli, R.K., Conrad, M., Bayir, H.: Cardiolipin signaling
mechanisms: Collapse of asymmetry and oxidation. Antioxid. Redox Signal. 22, 1667-1680 (2015)
Karp, N.A.°, Meehan, T.F., Morgan, H., Mason, J.C., Blake, A., Kurbatova, N., Smedley, D., Jacobsen, J.,
Mott, R.F., Iyer, V., Matthews, P., Melvin, D.G., Wells, S., Flenniken, A.M., Masuya, H., Wakana, S., White,
J.K., Lloyd, K.C.K., Reynolds, C.L., Paylor, R., West, D.B., Svenson, K.L., Chesler, E.J., Hrabě de Angelis,
M., Tocchini-Valentini, G.P., Sorg, T., Herault, Y., Parkinson, H., Mallon, A.M., Brown, S.D.: Applying the
ARRIVE guidelines to an in vivo database. PLoS Biol. 13:e1002151 (2015)
Kastenmüller, G., Raffler, J., Gieger, C., Suhre, K.°: Genetics of human metabolism: An update. Hum.
Mol. Genet. 24, R93-R101 (2015)
page 43 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Kato, N.°, Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., Kelly, T.N., Saleheen, D., Lehne, B.,
Leach, I.M., Drong, A.W., Abbott, J., Wahl, S., Tan, S.T., Scott, W.R., Campanella, G., Chadeau-Hyam, M.,
Afzal, U., Ahluwalia, T.S., Bonder, M.J., Chen, P., Dehghan, A., Edwards, T.L., Esko, T., Go, M.J., Harris,
S.E., Hartiala, J., Kasela, S., Kasturiratne, A., Khor, C.C., Kleber, M.E., Li, H., Mok, Z.Y., Nakatochi, M.,
Sapari, N.S., Saxena, R., Stewart, A.F., Stolk, L., Tabara, Y., Teh, A.L., Wu, Y., Wu, J.Y., Zhang, Y.-H., Aits,
I., da Silva Couto Alves, A., Das, S., Dorajoo, R., Hopewell, J.C., Kim, Y.K., Koivula, R.W., Luan, J.,
Lyytikäinen, L.P., Nguyen, Q.N., Pereira, M.A., Postmus, I., Raitakari, O.T., Bryan, M.S., Scott, R.A., Sorice,
R., Tragante, V., Traglia, M., White, J., Yamamoto, K., Adair, L.S., Ahmed, A., Akiyama, K., Asif, R., Aung,
T., Barroso, I., Bjonnes, A., Braun, T.R., Cai, H., Chang, L.C., Chen, C.H., Cheng, C.Y., Chong, Y.S., Collins,
R., Courtney, R., Davies, G., Delgado, G., Do, L.D., Doevendans, P.A., Gansevoort, R.T., Gao, Y.T.,
Grammer, T.B., Grarup, N., Grewal, J., Gu, D., Wander, G.S., Hartikainen, A.L., Hazen, S.L., He, J.°, Heng,
C.K., Hixson, J.E., Hofman, A., Hsu, C., Huang, W., Husemoen, L.L., Hwang, J.Y., Ichihara, S., Igase, M.,
Isono, M., Justesen, J.M., Katsuya, T., Kibriya, M.G., Kim, Y.J., Kishimoto, M., Koh, W.P., Kohara, K.,
Kumari, M., Kwek, K., Lee, N.R., Lee, J., Liao, J.M., Lieb, W., Liewald, D.C., Matsubara, T., Matsushita, Y.,
Meitinger, T., Mihailov, E., Milani, L., Mills, R., Mononen, N., Müller-Nurasyid, M., Nabika, T., Nakashima,
E., Ng, H.K., Nikus, K., Nutile, T., Ohkubo, T., Ohnaka, K., Parish, S., Paternoster, L., Peng, H., Peters, A.,
Pham, S.T., Pinidiyapathirage, M.J., Rahman, M., Rakugi, H., Rolandsson, O., Rozario, M.A., Ruggiero, D.,
Sala, C.F., Sarju, R., Shimokawa, K., Snieder, H., Sparsø, T., Spiering, W., Starr, J.M., Stott, D.J., Stram,
D.O., Sugiyama, T., Szymczak, S., Tang, W.H., Tong, L., Trompet, S., Turjanmaa, V., Ueshima, H.,
Uitterlinden, A.G., Umemura, S., Vaarasmaki, M., van Dam, R.M., van Gilst, W.H., van Veldhuisen, D.J.,
Viikari, J.S., Waldenberger, M., Wang, Y., Wang, A., Wilson, R.K., Wong, T.Y., Xiang, Y.B., Yamaguchi, S.,
Ye, X., Young, R.D., Young, T.L., Yuan, J.M., Zhou, X., Asselbergs, F.W., Ciullo, M., Clarke, R., Deloukas,
P., Franke, A., Franks, P.W., Franks, S., Friedlander, Y., Gross, M.D., Guo, Z., Hansen, T., Jarvelin, M.R.,
Jørgensen, T., Jukema, J.W., Kähönen, M., Kajio, H., Kivimaki, M., Lee, J.Y., Lehtimäki, T., Linneberg, A.,
Miki, T., Pedersen, O., Samani, N.J., Sørensen, T.I., Takayanagi, R., Toniolo, D., BIOS-Consortium,
CARDIoGRAMplusCD Consortium, LifeLines Cohort Study, InterAct Consortium, Ahsan, H., Allayee, H.,
Chen, Y.T., Danesh, J., Deary, I.J., Franco, O.H., Franke, L., Heijman, B.T., Holbrook, J.D., Isaacs, A., Kim,
B.J., Lin, X., Liu, J., Marz, W., Metspalu, A., Mohlke, K.L., Sanghera, D.K., Shu, X.O., van Meurs, J.B.,
Vithana, E., Wickremasinghe, A.R., Wijmenga, C., Wolffenbuttel, B.H., Yokota, M., Zheng, W., Zhu, D.,
Vineis, P., Kyrtopoulos, S.A., Kleinjans, J.C., McCarthy, M.I., Soong, R., Gieger, C., Scott, J., Teo, Y.Y.,
Elliott, P.°, Tai, E.S.°, van der Harst, P.°, Kooner, J.S.°, Chambers, J.C.°: Trans-ancestry genome-wide
association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA
methylation. Nat. Genet. 47, 1282-1293 (2015)
page 44 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Keller, M.F., Reiner, A.P., Okada, Y., van Rooij, F.J., Johnson, A.D., Chen, M.H., Smith, A.V., Morris, A.P.,
Tanaka, T., Ferrucci, L., Zonderman, A.B., Lettre, G., Harris, T., Garcia, M., Bandinelli, S., Qayyum, R.,
Yanek, L.R., Becker, D.M., Becker, L.C., Kooperberg, C., Keating, B.J., Reis, J., Tang, H., Boerwinkle, E.,
Kamatani, Y., Matsuda, K., Kamatani, N., Nakamura, Y., Kubo, M., Liu, S., Dehghan, A., Felix, J.F., Hofman,
A., Uitterlinden, A.G., van Duijn, C.M., Franco, O.H., Longo, D.L., Singleton, A.B., Psaty, B.M., Evans, M.K.,
Cupples, L.A., Rotter, J.I., O'Donnell, C.J., Takahashi, A., Wilson, J.G., Ganesh, S.K.°, Nalls, M.A.°,
CHARGE Consortium (Gieger, C., Illig, T., Meisinger, C., Prokisch, H., Wichmann, H.-E.), COGENT
Consortium, RIKEN Consortium: Trans-ethnic meta-analysis of white blood cell phenotypes. Hum. Mol.
Genet. 23, 6944-6960 (2014)
Kessler, T.#, Zhang, L.#, Liu, Z., Yin, X., Huang, Y., Wang, Y., Fu, Y., Mayr, M., Ge, Q., Xu, Q., Zhu, Y.,
Wang, X., Schmidt, K.J., de Wit, C., Erdmann, J., Schunkert, H., Aherrahrou, Z#°, Kong, W.#°, German
Mouse Clinic Consortium (Adamski, J., Adler, T., Aguilar-Pimentel, J.A., Amarie, O.V., Becker, L.,
Beckers, J., Brachthäuser, L., Busch, D.H., Calzada-Wack, J., Eickelberg, O., Fuchs, H.,
Gailus-Durner, V., Garrett, L., Graw, J., Hans, W., Hölter, S.M., Horsch, M., Hrabě de Angelis, M.,
Janik, D., Klein-Rodewald, T., Klingenspor, M., Klopstock, T., Lengger, C., Leuchtenberger, S., Maier,
H., Moreth, K., Neff, F., Ollert, M., Prehn, C., Puk, O., Rathkolb, B., Rozman, J., Steinkamp, R., Stöger,
C., Stöger, T., Vernaleken, A.M., Yildirim, A.Ö., Wurst, W., Zimprich, A.): ADAMTS-7 inhibits
re-endothelialization of injured arteries and promotes vascular remodeling via cleavage of thrombospondin-1.
Circulation 131, 1191-1201 (2015)
Kiermayer, C.°, Northrup, E., Schrewe, A., Walch, A.K., Hrabě de Angelis, M., Schoensiegel, F.,
Zischka, H., Prehn, C., Adamski, J., Bekeredjian, R., Ivandic, B., Kupatt, C., Brielmeier, M.: Heart-specific
knockout of the mitochondrial Thioredoxin reductase (Txnrd2) induces metabolic and contractile dysfunction
in the aging myocardium. J. Am. Heart Assoc. 4:e002153 (2015)
Kinnersley, B., Labussière, M., Holroyd, A., di Stefano, A.L., Broderick, P., Vijayakrishnan, J., Mokhtari, K.,
Delattre, J.Y., Gousias, K., Schramm, J., Schoemaker, M.J., Fleming, S.J., Herms, S., Heilmann, S.,
Schreiber, S., Wichmann, H.-E., Nöthen, M.M., Swerdlow, A., Lathrop, M., Simon, M., Bondy, M., Sanson,
M., Houlston, R.S.°: Genome-wide association study identifies multiple susceptibility loci for glioma. Nat.
Commun. 6:8559 (2015)
Kinnersley, B., Mitchell, J.S., Gousias, K., Schramm, J., Idbaih, A., Labussière, M., Marie, Y., Rahimian, A.,
Wichmann, H.-E., Schreiber, S., Hoang-Xuan, K., Delattre, J.Y., Nöthen, M.M., Mokhtari, K., Lathrop, M.,
Bondy, M., Simon, M., Houlston, R.S.: Quantifying the heritability of glioma using genome-wide complex trait
analysis. Sci. Rep. 5:17267 (2015)
Kirchberger, I.°, Wolf, K., Heier, M., Kuch, B., von Scheidt, W., Peters, A., Meisinger, C.: Are daylight
saving time transitions associated with changes in myocardial infarction incidence? Results from the German
MONICA/KORA Myocardial Infarction Registry. BMC Public Health 15:778 (2015)
page 45 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Kirchberger, I.°, Hunger, M., Stollenwerk, B., Seidl, H., Burkhardt, K., Kuch, B., Meisinger, C., Holle, R.:
Effects of a 3-year nurse-based case management in aged patients with acute myocardial infarction on
rehospitalisation, mortality, risk factors, physical functioning and mental health. A secondary analysis of the
randomized controlled KORINNA study. PLoS ONE 10:e0116693 (2015)
Kirchberger, I.°, Heier, M.°, Golüke, H., Kuch, B., von Scheidt, W., Peters, A., Meisinger, C.: Mismatch of
presenting symptoms at first and recurrent acute myocardial infarction. From the MONICA/KORA Myocardial
Infarction Registry. Eur. J. Prev. Cardiol. 23, 377-384 (2016) [published online 2015]
Kirsten, H., Scholz, M., Kovacs, P., Grallert, H., Peters, A., Strauch, K., Frank, J., Rietschel, M., Nöthen,
M.M., Witt, H., Rosendahl, J.°: Genetic variants of lipase activity in chronic pancreatitis. Gut 65, 184-185
(2016) [published online 2015]
Klüppelholz, B., Thorand, B., Koenig, W., de Las Heras Gala, T., Meisinger, C., Huth, C., Giani, G.,
Franks, P.W., Roden, M., Rathmann, W., Peters, A., Herder, C.°: Association of subclinical inflammation
with deterioration of glycaemia before the diagnosis of type 2 diabetes: The KORA S4/F4 study. Diabetologia
58, 2269-2277 (2015)
Kneipp, M., Estrada, H., Lauri, A., Turner, J.E., Ntziachristos, V., Westmeyer, G.G., Razansky, D.°:
Volumetric tracking of migratory melanophores during zebrafish development by optoacoustic microscopy.
Mech. Dev. 138, 300-304 (2015)
Kobayashi, S., Sato, M., Kasakoshi, T., Tsutsui, T., Sugimoto, M., Osaki, M., Okada, F., Igarashi, K.,
Hiratake, J., Homma, T., Conrad, M., Fujii, J., Soga, T., Bannai, S., Sato, H.°: Cystathionine is a novel
substrate of cystine/glutamate transporter: Implications for immune function. J. Biol. Chem. 290, 8778-8788
(2015)
Koch, J., Freisinger, P., Feichtinger, R.G., Zimmermann, F.A., Rauscher, C., Wagentristl, H.P.,
Konstantopoulou, V., Seidl, R., Haack, T.B., Prokisch, H., Ahting, U., Sperl, W., Mayr, J.A., Maier, E.M.°:
Mutations in TTC19: Expanding the molecular, clinical and biochemical phenotype. Orphanet J. Rare Dis.
10:40 (2015)
Koch, M., Baurecht, H., Ried, J.S., Rodriguez, E., Schlesinger, S., Volks, N., Gieger, C., Rückert, I.-M.,
Heinrich, L., Willenborg, C., Smith, C., Peters, A., Thorand, B., Koenig, W., Lamina, C., Jansen, H.,
Kronenberg, F., Seissler, J., Thiery, J., Rathmann, W., Schunkert, H., Erdmann, J., Barker, J., Nair, R.P.,
Tsoi, L.C., Elder, J.T., Mrowietz, U., Weichenthal, M., Mucha, S., Schreiber, S., Franke, A., Schmitt, J., Lieb,
W., Weidinger, S.°: Psoriasis and cardiometabolic traits: Modest association but distinct genetic
architectures. J. Invest. Dermatol. 135, 1283-1293 (2015)
page 46 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Kohl, S.°, Zobor, D., Chiang, W.C., Weisschuh, N., Staller, J., Menendez, I.G., Chang, S., Beck, S.C.,
Garrido, M.G., Sothilingam, V., Seeliger, M.W., Stanzial, F., Benedicenti, F., Inzana, F., Héon, E., Vincent,
A., Beis, J., Strom, T.M., Rudolph, G., Roosing, S., Hollander, A.I., Cremers, F.P., Lopez, I., Ren, H., Moore,
A.T., Webster, A.R., Michaelides, M., Koenekoop, R.K., Zrenner, E., Kaufman, R.J., Tsang, S.H., Wissinger,
B., Lin, J.H.°: Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction
disorder achromatopsia. Nat. Genet. 47, 757-765 (2015)
Kolder, I.C., Tanck, M.W., Postema, P.G., Barc, J., Sinner, M.F., Zumhagen, S., Husemann, A., Stallmeyer,
B., Koopmann, T.T., Hofman, N., Pfeufer, A., Lichtner, P., Meitinger, T., Beckmann, B.M., Myerburg, R.J.,
Bishopric, N.H., Roden, D.M., Kääb, S., Wilde, A.A., Schott, J.J., Schulze-Bahr, E., Bezzina, C.R.°: Analysis
for genetic modifiers of disease severity in patients with long QT syndrome type 2. Circ. Cardiovasc. Genet.
8, 447-456 (2015)
Kong, B., Wu, W., Cheng, T., Schlitter, A.M., Qian, C., Bruns, P., Jian, Z., Jager, C., Regel, I., Raulefs, S.,
Behler, N., Irmler, M., Beckers, J., Friess, H., Erkan, M., Siveke, J.T., Tannapfel, A., Hahn, S.A., Theis,
F.J., Esposito, I., Kleeff, J., Michalski, C.W.°: A subset of metastatic pancreatic ductal adenocarcinomas
depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling. Gut 65, 647-657
(2016) [published online 2015]
Kraus, U.°, Breitner, S., Hampel, R., Wolf, K., Cyrys, J., Geruschkat, U., Gu, J., Radon, K., Peters, A.,
Schneider, A.E.: Individual daytime noise exposure in different microenvironments. Environ. Res. 140,
479-487 (2015)
Kreuzer, M.°, Auvinen, A., Cardis, E., Hall, J., Jourdain, J.R., Laurier, D., Little, M.P., Peters, A., Raj, K.,
Russell, N.S., Tapio, S., Zhang, W., Gomolka, M.: Low-dose ionising radiation and cardiovascular diseases
– strategies for molecular epidemiological studies in Europe. Mutat. Res.- Rev. Mutat. Res. 764, 90-100
(2015)
Kreyling, W.G.°, Abdelmonem, A.M., Ali, Z., Alves, F., Geiser, M., Haberl, N., Hartmann, R., Hirn, S., de
Aberasturi, D.J., Kantner, K., Khadem-Saba, G., Montenegro, J.M., Rejman, J., Rojo, T., de Larramendi,
I.R., Ufartes, R., Wenk, A., Parak, W.J.°: In vivo integrity of polymer-coated gold nanoparticles. Nat.
Nanotechnol. 10, 619-623 (2015)
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#
Krumsiek, J. , Mittelstraß, K. , Do, K.T., Stückler, F., Ried, J.S., Adamski, J., Peters, A., Illig, T.,
Kronenberg, F., Friedrich, N., Nauck, M., Pietzner, M., Mook-Kanamori, D.O., Suhre, K., Gieger, C.,
Grallert, H., Theis, F.J.°, Kastenmüller, G.°: Gender-specific pathway differences in the human serum
metabolome. Metabolomics 11, 1815-1833 (2015)
Kruse, M., Keyhani-Nejad, F., Isken, F., Nitz, B., Kretschmer, A., Reischl, E., de Las Heras Gala, T.,
Osterhoff, M.A., Grallert, H., Pfeiffer, A.F.: A high fat diet during mouse pregnancy and lactation targets
GIP-regulated metabolic pathways in adult male offspring. Diabetes 65, 574-584 (2016)
page 47 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Kumar, D., Dedic, N., Flachskamm, C., Voulé, S., Deussing, J.M., Kimura, M.°: CACNA1C (Cav1.2)
modulates electroencephalographic rhythm and rapid eye movement sleep recovery. Sleep 38, 1371-1380
(2015)
Kun-Rodrigues, C.#, Ganos, C.#, Guerreiro, R., Schneider, S.A., Schulte, C., Lesage, S., Darwent, L.,
Holmans, P., Singleton, A., International Parkinson's Disease Genomics Consortium (IPDGC) (Illig, T.,
Lichtner, P.), Bhatia, K., Bras, J.°: A systematic screening to identify de novo mutations causing sporadic
early-onset Parkinson's disease. Hum. Mol. Genet. 24, 6711-6720 (2015)
Kunz, M.°, König, I.R., Schillert, A., Kruppa, J., Ziegler, A., Grallert, H., Müller-Nurasyid, M., Lieb, W.,
Franke, A., Ranki, A., Panelius, J., Koskenmies, S., Hasan, T., Kere, J., Rönn, A.C., Simon, J.C., Schmidt,
E., Wenzel, J., Tüting, T., Landsberg, J., Zeller, T., Blankenberg, S., Gläser, R., Patsinakidis, N., Kuhn, A.,
Ibrahim, S.M.: Genome-wide association study identifies new susceptibility loci for cutaneous lupus
erythematosus. Exp. Dermatol. 24, 510-515 (2015)
Kunze, S., Dalke, C., Fuchs, H., Klaften, M., Rössler, U., Hornhardt, S., Gomolka, M., Puk, O., Sabrautzki,
S., Kulka, U., Hrabě de Angelis, M., Graw, J.°: New mutation in the mouse Xpd/Ercc2 gene leads to
recessive cataracts. PLoS ONE 10:e0125304 (2015)
Ladwig, K.-H., Lukaschek, K., Baumert, J.J.: Wie Stress im Beruf das Herz schädigt. Dtsch. Ärztebl. 112,
30-32 (2015)
Lagouge, M., Mourier, A., Lee, H.J., Spåhr, H., Wai, T., Kukat, C., Silva Ramos, E., Motori, E., Busch, J.D.,
Siira, S., German Mouse Clinic Consortium (Larsson, N.G.°, Aguilar-Pimentel, J.A., Amarie, O.V., Becker,
L., Beckers, J., Brachthäuser, L., Calzada-Wack, J., Eickelberg, O., Gailus-Durner, V., Garrett, L.,
Graw, J., Hans, W., Hölter, S.M., Horsch, M., Hrabě de Angelis, M., Janik, D., Klein-Rodewald, T.,
Lengger, C., Leuchtenberger, S., Maier, H., Moreth, K., Neff, F., Östereicher, M., Puk, O., Rácz, I.,
Rathkolb, B., Rozman, J., Steinkamp, R., Stöger, C., Stöger, T., Vernaleken, A.M., Wurst, W., Yildirim,
A.Ö., Zimprich, A.), Kremmer, E., Filipovska, A.°: SLIRP regulates the rate of mitochondrial protein
synthesis and protects LRPPRC from degradation. PLoS Genet. 11:e1005423 (2015)
#
#
Lal, D. , Ruppert, A.K. , Trucks, H., Schulz, H., de Kovel, C.G.F., Kasteleijn-Nolst Trenité, D., Sonsma, A.C.,
Koeleman, B.P., Lindhout, D., Weber, Y.G., Lerche, H., Kapser, C., Schankin, C.J., Kunz, W.S., Surges, R.,
Elger, C.E., Gaus, V., Schmitz, B., Helbig, I., Muhle, H., Stephani, U., Klein, K.M., Rosenow, F., Neubauer,
B.A., Reinthaler, E.M., Zimprich, F., Feucht, M., Møller, R.S., Hjalgrim, H., de Jonghe, P., Suls, A., Lieb, W.,
Franke, A., Strauch, K., Gieger, C., Schurmann, C., Schminke, U., Nürnberg, P., Sander, T.°: Burden
analysis of rare microdeletions suggests a strong impact of neurodevelopmental genes in genetic
generalised epilepsies. PLoS Genet. 11:e1005226 (2015)
page 48 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Lanki, T.°, Hampel, R., Tiittanen, P., Andrich, S., Beelen, R., Brunekreef, B., Dratva, J., de Faire, U., Fuks,
K.B., Hoffman, B., Imboden, M., Jousilahti, P., Koenig, W., Mahabadi, A.A., Künzli, N., Pedersen, N.L.,
Penell, J., Pershagen, G., Probst-Hensch, N.M., Schaffner, E., Schindler, C., Sugiri, D., Swart, W.J., Tsai,
M.Y., Turunen, A.W., Weinmayr, G., Wolf, K., Yli-Tuomi, T., Peters, A.: Air pollution from road traffic and
systemic inflammation in adults: A cross-sectional analysis in the European ESCAPE project. Environ.
Health Perspect. 123, 785-791 (2015)
Laxy, M.°, Hunger, M., Stark, R.G., Meisinger, C., Kirchberger, I., Heier, M., von Scheidt, W., Holle, R.:
The burden of diabetes mellitus in patients with coronary heart disease: A methodological approach to
assess quality-adjusted life-years based on individual-level longitudinal survey data. Value Health 18,
969-976 (2015)
Laxy, M.°, Stark, R.G., Meisinger, C., Kirchberger, I., Heier, M., von Scheidt, W., Holle, R.: The
effectiveness of German Disease Management Programs (DMPs) in patients with type 2 diabetes mellitus
and coronary heart disease: Results from an observational longitudinal study. Diabetol. Metab. Syndr. 7:77
(2015)
Lee, S., Rose, S., Metodiev, M.D., Becker, L., Vernaleken, A.M., Klopstock, T., Gailus-Durner, V., Fuchs,
H., Hrabě de Angelis, M., Douthwaite, S., Larsson, N.-G.°: Overexpression of the mitochondrial
methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status of hearing. Hum.
Mol. Genet. 24, 7286-7294 (2015)
#
#
#
Li, J. , Jørgensen, S.F. , Maggadottir, S.M. , Bakay, M., Warnatz, K., Glessner, J.T., Pandey, R.C., Salzer,
U., Schmidt, R.E., Perez, E., Resnick, E., Goldacker, S., Buchta, M., Witte, T., Padyukov, L., Videm, V.,
Folseraas, T., Atschekzei, F., Elder, J.T., Nair, R.P., Winkelmann, J., Gieger, C., Nöthen, M.M., Büning, C.,
Brand, S., Sullivan, K.E., Orange, J.S., Fevang, B., Schreiber, S., Lieb, W., Aukrust, P., Chapel, H.,
Cunningham-Rundles, C., Franke, A., Karlsen, T.H., Grimbacher, B., Hakonarson, H.°, Hammarström, L.,
Ellinghaus, E.: Association of CLEC16A with human common variable immunodeficiency disorder and role in
murine B cells. Nat. Commun. 6:6804 (2015)
Libuda, L.°, Mesch, C.M., Stimming, M., Demmelmair, H., Koletzko, B., Warschburger, P., Blanke, K.,
Reischl, E., Kalhoff, H., Kersting, M.: Fatty acid supply with complementary foods and LC-PUFA status in
healthy infants: Results of a randomised controlled trial. Eur. J. Nutr., DOI: 10.1007/s00394-015-0982-2
(2015)
Lichtenauer, U.D.°, di Dalmazi, G., Slater, E.P., Wieland, T., Kuebart, A., Schmittfull, A., Schwarzmayr, T.,
Diener, S., Wiese, D., Thasler, W.E., Reincke, M., Meitinger, T., Schott, M., Fassnacht, M., Bartsch, D.K.,
Strom, T.M., Beuschlein, F.: Frequency and clinical correlates of somatic Ying Yang 1 mutations in sporadic
insulinomas. J. Clin. Endocrinol. Metab. 100, E776-E782 (2015)
Linder, B., Weber, S., Dittmann, K.H., Adamski, J., Hahn, H., Uhmann, A.°: A functional and putative
physiological role of calcitriol in Patched1/Smoothened interaction. J. Biol. Chem. 290, 19614-19628 (2015)
page 49 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Linnemann, J., Miura, H., Meixner, L.K., Irmler, M., Kloos, U., Hirschi, B., Bartsch, H.S., Sass, S.,
Beckers, J., Theis, F.J., Gabka, C., Sotlar, K., Scheel, C.°: Quantification of regenerative potential in
primary human mammary epithelial cells. Development 142, 3239-3251 (2015)
Liu, X., Tian, Y., Meng, Z., Chen, Y., Ho, I.H., Choy, K.W., Lichtner, P., Wong, S.H., Yu, J., Gin, T., Wu,
W.K., Cheng, C.H., Chan, M.T.°: Up-regulation of cathepsin G in the development of chronic postsurgical
pain: An experimental and clinical genetic study. Anesthesiology 123, 838-850 (2015)
Livshits, G., Macgregor, A.J., Gieger, C., Malkin, I., Moayyeri, A., Grallert, H., Emeny, R.T., Spector, T.,
Kastenmüller, G., Williams, F.M.: An omics investigation into chronic widespread musculoskeletal pain
reveals epiandrosterone sulfate as a potential biomarker. Pain 156, 1845-1851 (2015)
page 50 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
#
#
#
#
#
Locke, A.E. , Kahali, B. , Berndt, S.I. , Justice, A.E. , Pers, T.H. , Day, F.R., Powell, C.A., Vedantam, S.,
Buchkovich, M.L., Yang, J., Croteau-Chonka, D.C., Esko, T., Fall, T., Ferreira, T., Gustafsson, S., Kutalik, Z.,
Luan, J., Mägi, R., Randall, J.C., Winkler, T.W., Wood, A.R., Workalemahu, T., Faul, J.D., Smith, J.A., Hua
Zhao, J., Zhao, W., Chen, J., Fehrmann, R.S.N., Hedman, A.K., Karjalainen, J., Schmidt, E.M., Absher, D.,
Amin, N., Anderson, D., Beekman, M., Bolton, J.L., Bragg-Gresham, J.L., Buyske, S., Demirkan, A., Deng,
G., Ehret, G.B., Feenstra, B., Feitosa, M.F., Fischer, K., Goel, A., Gong, J., Jackson, A.U., Kanoni, S.,
Kleber, M.E., Kristiansson, K., Lim, U., Lotay, V., Mangino, M., Mateo Leach, I., Medina-Gomez, C.,
Medland, S.E., Nalls, M.A., Palmer, C.D., Pasko, D., Pechlivanis, S., Peters, M.J., Prokopenko, I., Shungin,
D., Stancáková, A., Strawbridge, R.J., Ju Sung, Y., Tanaka, T., Teumer, A., Trompet, S., van der Laan,
S.W., van Setten, J., van Vliet-Ostaptchouk, J.V., Wang, Z., Yengo, L., Zhang, W., Isaacs, A., Albrecht, E.,
Ärnlöv, J., Arscott, G.M., Attwood, A.P., Bandinelli, S., Barrett, A., Bas, I.N., Bellis, C., Bennett, A.J., Berne,
C., Blagieva, R., Blüher, M., Böhringer, S., Bonnycastle, L.L., Böttcher, Y., Boyd, H.A., Bruinenberg, M.,
Caspersen, I.H., Chen, Y.D.I., Clarke, R., Daw, E.W., de Craen, A.J., Delgado, G., Dimitriou, M., Doney,
A.S., Eklund, N., Estrada, K., Eury, E., Folkersen, L., Fraser, R.M., Garcia, M.E., Geller, F., Giedraitis, V.,
Gigante, B., Go, A.S., Golay, A., Goodall, A.H., Gordon, S.D., Gorski, M., Grabe, H.J., Grallert, H.,
Grammer, T.B., Gräßler, J., Grönberg, H., Groves, C.J., Gusto, G., Haessler, J., Hall, P., Haller, T.,
Hallmans, G., Hartman, C.A., Hassinen, M., Hayward, C., Heard-Costa, N.L., Helmer, Q., Hengstenberg, C.,
Holmen, O.L., Hottenga, J.J., James, A.L., Jeff, J.M., Johansson, A., Jolley, J., Juliusdottir, T., Kinnunen, L.,
Koenig, W., Koskenvuo, M., Kratzer, W., Laitinen, J., Lamina, C., Leander, K., Lee, N.R., Lichtner, P., Lind,
L., Lindstrom, J., Lo, K.S., Lobbens, S., Lorbeer, R., Lu, Y., Mach, F., Magnusson, P.K., Mahajan, A.,
McArdle, W.L., McLachlan, S., Menni, C., Merger, S., Mihailov, E., Milani, L., Moayyeri, A., Monda, K.L.,
Morken, M.A., Mulas, A., Müller, G., Müller-Nurasyid, M., Musk, A.W., Nagaraja, R., Nöthen, M.M., Nolte,
I.M., Pilz, S., Rayner, N.W., Renström, F., Rettig, R., Ried, J.S., Ripke, S., Robertson, N.R., Rose, L.M.,
Sanna, S., Scharnagl, H., Scholtens, S., Schumacher, F.R., Scott, W.R., Seufferlein, T., Shi, J., Smith, A.V.,
Smolonska, J., Stanton, A.V., Steinthorsdottir, V., Stirrups, K., Stringham, H.M., Sundström, J., Swertz, M.A.,
Swift, A.J., Syvanen, A.C., Tan, S.T., Tayo, B.O., Thorand, B., Thorleifsson, G., Tyrer, J.P., Uh, H.W.,
Vandenput, L., Verhulst, F.C., Vermeulen, S.H., Verweij, N., Vonk, J.M., Waite, L.L., Warren, H.R.,
Waterworth, D., Weedon, M.N., Wilkens, L.R., Willenborg, C., Wilsgaard, T., Wojczynski, M.K., Wong, A.,
Wright, A.F., Zhang, Q., Brennan, E.P., Choi, M., Dastani, Z., Drong, A.W., Eriksson, P., Franco-Cereceda,
A., Gådin, J.R., Gharavi, A.G., Goddard, M.E., Handsaker, R.E., Huang, J., Karpe, F., Kathiresan, S.,
Keildson, S., Kiryluk, K., Kubo, M., Lee, J.Y., Liang, L., Lifton, R.P., Ma, B., McCarroll, S.A., McKnight, A.J.,
Min, J.L., Moffatt, M.F., Montgomery, G.W., Murabito, J.M., Nicholson, G., Nyholt, D.R., Okada, Y., Perry,
J.R., Dorajoo, R., Reinmaa, E., Salem, R.M., Sandholm, N., Scott, R.A., Stolk, L., Takahashi, A., van't Hooft,
F.M., Vinkhuyzen, A.A., Westra, H.J., Zheng, W., Zondervan, K.T., Heath, A.C., Arveiler, D., Bakker, S.J.,
Beilby, J., Bergman, R.N., Blangero, J., Bovet, P., Campbell, H., Caulfield, M.J., Cesana, G., Chakravarti, A.,
Chasman, D.I., Chines, P.S., Collins, F.S., Crawford, D.C., Cupples, L.A., Cusi, D., Danesh, J., de Faire, U.,
den Ruijter, H.M., Dominiczak, A.F., Erbel, R., Erdmann, J., Eriksson, J.G., Farrall, M., Felix, S.B.,
Ferrannini, E., Ferrieres, J., Ford, I., Forouhi, N.G., Forrester, T., Franco, O.H., Gansevoort, R.T., Gejman,
P.V., Gieger, C., Gottesman, O., Gudnason, V., Gyllensten, U., Hall, A.S., Harris, T.B., Hattersley, A.T.,
Hicks, A.A., Hindorff, L.A., Hingorani, A.D., Hofman, A., Homuth, G., Kees Hovingh, G., Humphries, S.E.,
Hunt, S.C., Hyppönen, E., Illig, T., Jacobs, K.B., Jarvelin, M.R., Jockel, K.H., Johansen, B., Jousilahti, P.,
Jukema, J.W., Jula, A.M., Kaprio, J., Kastelein, J.J., Keinanen-Kiukaanniemi, S.M., Kiemeney, L.A., Knekt,
page 51 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
P., Kooner, J.S., Kooperberg, C., Kovacs, P., Kraja, A.T., Kumari, M., Kuusisto, J., Lakka, T.A., Langenberg,
C., Le Marchand, L., Lehtimäki, T., Lyssenko, V., Männisto, S., Marette, A., Matise, T.C., McKenzie, C.A.,
McKnight, B., Moll, F.L., Morris, A.D., Morris, A.P., Murray, J.C., Nelis, M., Ohlsson, C., Oldehinkel, A.J.,
Ong, K.K., Madden, P.A., Pasterkamp, G., Peden, J.F., Peters, A., Postma, D.S., Pramstaller, P.P., Price,
J.F., Qi, L., Raitakari, O.T., Rankinen, T., Rao, D.C., Rice, T.K., Ridker, P.M., Rioux, J.D., Ritchie, M.D.,
Rudan, I., Salomaa, V., Samani, N.J., Saramies, J., Sarzynski, M.A., Schunkert, H., Schwarz, P.E., Sever,
P., Shuldiner, A.R., Sinisalo, J., Stolk, R.P., Strauch, K., Tönjes, A., Tregouet, D.A., Tremblay, A., Tremoli,
E., Virtamo, J., Vohl, M.C., Völker, U., Waeber, G., Willemsen, G., Witteman, J.C., Zillikens, M.C., Adair,
L.S., Amouyel, P., Asselbergs, F.W., Assimes, T.L., Bochud, M., Boehm, B.O., Boerwinkle, E., Bornstein,
S.R., Bottinger, E.P., Bouchard, C., Cauchi, S., Chambers, J.C., Chanock, S.J., Cooper, R.S., de Bakker,
P.I., Dedoussis, G., Ferrucci, L., Franks, P.W., Froguel, P., Groop, L.C., Haiman, C.A., Hamsten, A., Hui, J.,
Hunter, D.J., Hveem, K., Kaplan, R.C., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Martin, N.G., Marz, W.,
Melbye, M., Metspalu, A., Moebus, S., Munroe, P.B., Njølstad, I., Oostra, B.A., Palmer, C.N., Pedersen, N.L.,
Perola, M., Perusse, L., Peters, U., Power, C., Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo,
T.E., Saleheen, D., Sattar, N., Schadt, E.E., Schlessinger, D., Slagboom, P.E., Snieder, H., Spector, T.D.,
Thorsteinsdottir, U., Stumvoll, M., Tuomilehto, J., Uitterlinden, A.G., Uusitupa, M., van der Harst, P., Walker,
M., Wallaschofski, H., Wareham, N.J., Watkins, H., Weir, D.R., Wichmann, H.-E., Wilson, J.F., Zanen, P.,
Borecki, I.B., Deloukas, P., Fox, C.S., Heid, I.M., O'Connell, J.R., Strachan, D.P., Stefansson, K., van Duijn,
C.M., Abecasis, G.R., Franke, L., Frayling, T.M., McCarthy, M.I., Visscher, P.M., Scherag, A., Willer, C.J.,
Boehnke, M., Mohlke, K.L., Lindgren, C.M., Beckmann, J.S., Barroso, I., North, K.E., Ingelsson, E.,
Hirschhorn, J.N.°, Loos, R.J.°, Speliotes, E.K.°: Genetic studies of body mass index yield new insights for
obesity biology. Nature 518, 197-206 (2015)
Looker, H.C.°, Colombo, M., Agakov, F.V., Zeller, T., Groop, L.C., Thorand, B., Palmer, C.N., Hamsten, A.,
dé Fairé, U.H., Nogoceke, E., Livingstone, S.J., Salomaa, V.V., Leander, K., Barbarini, N.N., Bellazzi, R., van
Zuydam, N., McKeigue, P.M., Colhoun, H.M., SUMMIT Investigators: Protein biomarkers for the prediction of
cardiovascular disease in type 2 diabetes. Diabetologia 58, 1363-1371 (2015)
#
#
Lukaschek, K. , Engelhardt, H. , Baumert, J.J., Ladwig, K.-H.°: No correlation between rates of suicidal
ideation and completed suicides in Europe: Analysis of 49,008 participants (55+ years) based on the Survey
of Health, Ageing and Retirement in Europe (SHARE). Eur. Psych. 30, 874-879 (2015)
page 52 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
#
#
Lunetta, K.L. , Day, F.R. , Sulem, P., Ruth, K.S., Tung, J.Y., Hinds, D.A., Esko, T., Elks, C.E., Altmaier,
E.M., He, C., Huffman, J.E., Mihailov, E., Porcu, E., Robino, A., Rose, L.M., Schick, U.M., Stolk, L., Teumer,
A., Thompson, D.J., Traglia, M., Wang, C.A., Yerges-Armstrong, L.M., Antoniou, A.C., Barbieri, C., Coviello,
A.D., Cucca, F., Demerath, E.W., Dunning, A.M., Gandin, I., Grove, M.L., Gudbjartsson, D.F., Hocking, L.J.,
Hofman, A., Huang, J., Jackson, R.D., Karasik, D., Kriebel, J., Lange, E.M., Lange, L.A., Langenberg, C., Li,
X., Luan, J., Mägi, R., Morrison, A.C., Padmanabhan, S., Pirie, A., Polasek, O., Porteous, D.J., Reiner, A.P.,
Rivadeneira, F., Rudan, I., Sala, C.F., Schlessinger, D., Scott, R.A., Stöckl, D., Visser, J.A., Völker, U.,
Vozzi, D., Wilson, J.G., Zygmunt, M., EPIC-Interact Consortium, Generation Scotland Consortium,
Boerwinkle, E., Buring, J.E., Crisponi, L., Easton, D.F., Hayward, C., Hu, F.B., Liu, S., Metspalu, A., Pennell,
C.E., Ridker, P.M., Strauch, K., Streeten, E.A., Toniolo, D., Uitterlinden, A.G., Ulivi, S., Völzke, H.,
Wareham, N.J., Wellons, M., Franceschini, N., Chasman, D.I., Thorsteinsdottir, U., Murray, A., Stefansson,
K., Murabito, J.M., Ong, K.K.°, Perry, J.R.°: Rare coding variants and X-linked loci associated with age at
menarche. Nat. Commun. 6:7756 (2015)
Ma, C., Boehnke, M., Lee, S.°, GoT2D Consortium (Gieger, C., Grallert, H., Hrabě de Angelis, M., Huth,
C., Kriebel, J., Meisinger, C., Meitinger, T., Müller-Nurasyid, M., Peters, A., Ried, J.S., Strauch, K.,
Strom, T.M.): Evaluating the calibration and power of three gene-based association tests of rare variants for
the X chromosome. Genet. Epidemiol. 39, 499-508 (2015)
#
#
#
Mahajan, A. , Sim, X. , Ng, H.J. , Manning, A., Rivas, M.A., Highland, H.M., Locke, A.E., Grarup, N., Im,
H.K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K.J., Teslovich, T.M., Rayner,
N.W., Robertson, N.R., Beer, N.L., Rundle, J.K., Bork-Jensen, J., Ladenvall, C., Blancher, C., Buck, D.,
Buck, G., Burtt, N.P., Gabriel, S., Gjesing, A.P., Groves, C.J., Hollensted, M., Huyghe, J.R., Jackson, A.U.,
Jun, G., Justesen, J.M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K.S., Stringham, H.M.,
Syvanen, A.C., Trakalo, J., Abecasis, G., Bell, G.I., Blangero, J., Cox, N.J., Duggirala, R., Hanis, C.L.,
Seielstad, M., Wilson, J.G., Christensen, C., Brandslund, I., Rauramaa, R., Surdulescu, G.L., Doney, A.S.,
Lannfelt, L., Linneberg, A., Isomaa, B., Tuomi, T., Jørgensen, M.E., Jørgensen, T., Kuusisto, J., Uusitupa,
M., Salomaa, V., Spector, T.D., Morris, A.D., Palmer, C.N., Collins, F.S., Mohlke, K.L., Bergman, R.N.,
Ingelsson, E., Lind, L., Tuomilehto, J., Hansen, T., Watanabe, R.M., Prokopenko, I., Dupuis, J., Karpe, F.,
Groop, L., Laakso, M., Pedersen, O., Florez, J.C., Morris, A.P., Altshuler, D., Meigs, J.B., Boehnke, M.,
McCarthy, M.I., Lindgren, C.M.°, Gloyn, A.L.°, T2D-GENES Consortium, GoT2D Consortium (Hrabě de
Angelis, M., Gieger, C., Grallert, H., Huth, C., Kriebel, J., Meisinger, C., Meitinger, T., Peters, A., Ried,
J.S., Strauch, K., Strom, T.M.), GoT2D Consortium (Müller-Nurasyid, M.): Identification and functional
characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the
G6PC2-ABCB11 locus. PLoS Genet. 11:e1004876 (2015)
Maier, H.°, Schütt, C., Steinkamp, R., Hurt, A., Schneltzer, E., Gormanns, P., Lengger, C., Griffiths, M.,
Melvin, D., Agrawal, N., Alcantara, R., Evans, A., Gannon, D., Holroyd, S., Kipp, C., Raj, N. P., Richardson,
D., Leblanc, S., Vasseur, L., Masuya, H., Kobayashi, K., Suzuki, T., Tanaka, N., Wakana, S., Walling, A.,
Clary, D., Gallegos, J., Fuchs, H., Hrabě de Angelis, M.°, Gailus-Durner, V.: Principles and application of
LIMS in mouse clinics. Mamm. Genome 26, 467-481 (2015)
page 53 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Marcos, S., González-Lázaro, M., Beccari, L., Carramolino, L., Martin-Bermejo, M.J., Amarie, O.V., Martín,
D.M., Torroja, C., Bogdanović, O., Doohan, R., Puk, O., Hrabě de Angelis, M., Graw, J., Gómez-Skarmeta,
J.L., Casares, F., Torres, M.°, Bovolenta, P.°: Meis1 coordinates a network of genes implicated in eye
development and microphthalmia. Development 142, 3009-3020 (2015)
Marenholz, I., Esparza-Gordillo, J., Ruschendorf, F., Bauerfeind, A., Strachan, D.P., Spycher, B.D.,
Baurecht, H., Margaritte-Jeannin, P., Saaf, A., Kerkhof, M., Ege, M., Baltic, S., Matheson, M.C., Li, J.,
Michel, S., Ang, W.Q., McArdle, W., Arnold, A., Homuth, G., Demenais, F., Bouzigon, E., Söderhäll, C.,
Pershagen, G., de Jongste, J.C., Postma, D.S., Braun-Fahrländer, C., Horak, E., Ogorodova, L.M., Puzyrev,
V.P., Bragina, E.Y., Hudson, T.J., Morin, C., Duffy, D.L., Marks, G.B., Robertson, C.F., Montgomery, G.W.,
Musk, B., Thompson, P.J., Martin, N.G., James, A., Sleiman, P.M., Toskala, E., Rodriguez, E., Fölster-Holst,
R., Franke, A., Lieb, W., Gieger, C., Heinzmann, A., Rietschel, E., Keil, T., Cichon, S., Nöthen, M.M.,
Pennell, C.E., Sly, P.D., Schmidt, C.O., Matanovic, A., Schneider, V., Heinig, M., Hubner, N., Holt, P.G., Lau,
S., Kabesch, M., Weidinger, S., Hakonarson, H., Ferreira, M.A., Laprise, C., Freidin, M.B., Genuneit, J.,
Koppelman, G.H., Melén, E., Dizier, M.H., Henderson, A.J., Lee, Y.A.°: Meta-analysis identifies seven
susceptibility loci involved in the atopic march. Nat. Commun. 6:8804 (2015)
Marroquin, N., Stranz, S., Müller, K., Wieland, T., Ruf, W.P., Brockmann, S.J., Danzer, K.M., Borck, G.,
Hübers, A., Weydt, P., Meitinger, T., Strom, T.M., Rosenbohm, A., Ludolph, A.C., Weishaupt, J.H.°:
Screening for CHCHD10 mutations in a large cohort of sporadic ALS patients: No evidence for pathogenicity
of the p.P34S variant. Brain 139, E8-U10 (2016) [published online 2015]
Martinez-Ferre, A., Lloret-Quesada, C., Prakash, N., Wurst, W., Rubenstein, J.L., Martinez, S.°: Fgf15
regulates thalamic development by controlling the expression of proneural genes. Brain Struct. Funct., DOI:
10.1007/s00429-015-1089-5 (2015)
#
#
Masserdotti, G. , Gillotin, S. , Sutor, B., Drechsel, D., Irmler, M., Jørgensen, H.F., Sass, S., Theis, F.J.,
Beckers, J., Berninger, B., Guillemot, F.°, Götz, M.°: Transcriptional mechanisms of proneural factors and
REST in regulating neuronal reprogramming of astrocytes. Cell Stem Cell 17, 74-88 (2015)
Matsui, H.°, Namikawa, K., Köster, R.W.: Identification of the zebrafish red nucleus using wheat germ
agglutinin transneuronal tracing. Commun. Integr. Biol. 7:e994383 (2014)
Mayer, A.K., Rohrschneider, K., Strom, T.M., Glöckle, N., Kohl, S., Wissinger, B., Weisschuh, N.°:
Homozygosity mapping and whole-genome sequencing reveals a deep intronic PROM1 mutation causing
cone-rod dystrophy by pseudoexon activation. Eur. J. Hum. Genet. 24, 459-462 (2016) [published online
2015]
Mayr, J.A.°, Haack, T.B., Freisinger, P., Karall, D., Makowski, C.C., Koch, J., Feichtinger, R.G.,
Zimmermann, F.A., Rolinski, B., Ahting, U., Meitinger, T., Prokisch, H., Sperl, W.J.K.: Spectrum of
combined respiratory chain defects. J. Inherit. Metab. Dis. 38, 629-640 (2015)
page 54 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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McGuinn, L.A., Ward-Caviness, C.K., Neas, L.M., Schneider, A.E., Diaz-Sanchez, D., Cascio, W.E., Kraus,
W.E., Hauser, E., Dowdy, E., Haynes, C., Chudnovsky, A., Koutrakis, P., Devlin, R.B.: Association between
satellite-based estimates of long-term PM2.5 exposure and coronary artery disease. Environ. Res. 145, 9-17
(2016) [published online 2015]
Mellett, M., Atzei, P., Bergin, R., Horgan, A., Floß, T., Wurst, W., Callanan, J.J., Moynagh, P.N.°: Orphan
receptor IL-17RD regulates toll-like receptor signalling via SEFIR/TIR interactions. Nat. Commun. 6:6669
(2015)
#
#
Menni, C. , Graham, D. , Kastenmüller, G., Alharbi, N.H., Alsanos, S.M., McBride, M., Mangino, M.,
Titcombe, P., Shin, S.Y., Psatha, M., Geisendorfer, T., Huber, A., Peters, A., Wang-Sattler, R., Xu, T.,
Brosnan, M.J., Trimmer, J., Reichel, C., Mohney, R.P., Soranzo, N., Edwards, M.H., Cooper, C., Church,
A.C., Suhre, K., Gieger, C., Dominiczak, A.F., Spector, T.D., Padmanabhan, S.°, Valdes, A.M.: Metabolomic
identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension 66,
422-429 (2015)
Miller, M.°, Zorn, J., Brielmeier, M.: High-resolution melting curve analysis for identification of
Pasteurellaceae species in experimental animal facilities. PLoS ONE 10:e0142560 (2015)
Mons, U.°, Müezzinler, A., Gellert, C., Schöttker, B., Abnet, C.C., Bobak, M., de Groot, L., Freedman, N.D.,
Jansen, E., Kee, F., Kromhout, D., Kuulasmaa, K., Laatikainen, T., O'Doherty, M.G., Bueno-de-Mesquita, B.,
Orfanos, P., Peters, A., van der Schouw, Y.T., Wilsgaard, T., Wolk, A., Trichopoulou, A., Boffetta, P.,
Brenner, H., CHANCES Consortium: Impact of smoking and smoking cessation on cardiovascular events
and mortality among older adults: Meta-analysis of individual participant data from prospective cohort studies
of the CHANCES consortium. BMJ 350:h1551 (2015)
Mook-Kanamori, D.O.°, de Mutsert, R., Rensen, P.C., Prehn, C., Adamski, J., Heijer, M.D., le Cessie, S.,
Suhre, K., Rosendaal, F.R., van Dijk, K.W.: Type 2 diabetes is associated with postprandial amino acid
measures. Arch. Biochem. Biophys. 589, 138-144 (2015)
#
#
Moreth, K. °, Afonso, L.C. , Fuchs, H., Gailus-Durner, V., Katus, H.A., Bekerdjian, R., Lehmann, L., Hrabě
de Angelis, M.: High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin
transgene mice. Int. J. Cardiovasc. Imaging 31, 669-679 (2015)
Moutsianas, L.#, Jostins, L.#, Beecham, A.H., Dilthey, A.T., Xifara, D.K., Ban, M., Shah, T.S., Patsopoulos,
N.A., Alfredsson, L., Anderson, C.A., Attfield, K.E., Baranzini, S.E., Barrett, J., Binder, T.M.C., Booth, D.,
Buck, D., Celius, E.G., Cotsapas, C., D'Alfonso, S., Dendrou, C.A., Donnelly, P., Dubois, B., Fontaine, B.,
Fugger, L., Goris, A., Gourraud, P.A., Graetz, C., Hemmer, B., Hillert, J., Kockum, I., Leslie, S., Lill, C.M.,
Martinelli-Boneschi, F., Oksenberg, J.R., Olsson, T., Oturai, A., Saarela, J., Søndergaard, H.B., Spurkland,
A., Taylor, B., Winkelmann, J., Zipp, F., Haines, J.L., Pericak-Vance, M.A., Spencer, C.C.A., Stewart, G.,
Hafler, D.A., Ivinson, A.J., Harbo, H.F., Hauser, S.L., de Jager, P.L., Compston, A., McCauley, J.L., Sawcer,
S., McVean, G.°, International Multiple Sclerosis Genetics Consortium: Class II HLA interactions modulate
genetic risk for multiple sclerosis. Nat. Genet. 47, 1107-1113 (2015)
page 55 of 213
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joint first authors
° corresponding authors
HMGU authors are given in bold letters
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#
#
Moutsianas, L. °, Agarwala, V. , Fuchsberger, C., Flannick, J., Rivas, M.A., Gaulton, K.J., Albers, P.K.,
GoT2D Consortium (McCarthy, M.I.°, Gieger, C.), GoT2D Consortium (Grallert, H., Hrabě de Angelis, M.,
Huth, C., Kriebel, J., Meisinger, C., Meitinger, T., Müller-Nurasyid, M., Peters, A., Ried, J.S., Strauch,
K., Strom, T.M.), McVean, G., Boehnke, M., Altshuler, D.: The power of gene-based rare variant methods to
detect disease-associated variation and test hypotheses about complex disease. PLoS Genet. 11:e1005165
(2015)
Müezzinler, A., Mons, U.°, Gellert, C., Schöttker, B., Jansen, E., Kee, F., O'Doherty, M.G., Kuulasmaa, K.,
Freedman, N.D., Abnet, C.C., Wolk, A., Hakansson, N., Orsini, N., Wilsgaard, T., Bueno-de-Mesquita, B.,
van der Schouw, Y.T., Peeters, P.H., de Groot, L.C., Peters, A., Orfanos, P., Linneberg, A., Pisinger, C.,
Tamosiunas, A., Baceviciene, M., Luksiene, D., Bernotiene, G., Jousilahti, P., Petterson-Kymmer, U.,
Jansson, J.H., Söderberg, S., Eriksson, S., Jankovic, N., Sánchez, M.J., Veronesi, G., Sans, S., Drygas, W.,
Trichopoulou, A., Boffetta, P., Brenner, H.: Smoking and all-cause mortality in older adults: Results from the
CHANCES consortium. Am. J. Prev. Med. 49, e53–e63 (2015)
Müller, G.°, Wellmann, J., Hartwig, S., Greiser, K.H., Moebus, S., Jöckel, K.-H., Schipf, S., Völzke, H., Maier,
W., Meisinger, C., Tamayo, T., Rathmann, W., Berger, K.: Association of neighbourhood unemployment rate
with incident type 2 diabetes mellitus in five German regions. Diabet. Med. 32, 1017-1022 (2015)
Nahon, K.J.#, Boon, M.R.#°, Bakker, L.E.H., Prehn, C., Adamski, J., Jazet, I.M., van Dijk, K.W., Rensen,
P.C.N., Mook-Kanamori, D.O.: Physiological changes due to mild cooling in healthy lean males of white
Caucasian and South Asian descent: A metabolomics study. Arch. Biochem. Biophys. 589, 152-157 (2015)
Nalls, M.A.°, Saad, M., Noyce, A.J., Keller, M.F., Schrag, A., Bestwick, J.P., Traynor, B.J., Gibbs, J.R.,
Hernandez, D.G., Cookson, M.R., Morris, H.R., Williams, N., Gasser, T., Heutink, P., Wood, N., Hardy, J.,
Martinez, M., Singleton, A.B., International Parkinson's Disease Genomics Consortium (IPDGC) (Illig, T.,
Lichtner, P.), Wellcome Trust Case Control Consortium 2 (WTCCC2), North American Brain Expression
Consortium, United Kingdom Brain Expression Consortium (UKBEC): Genetic comorbidities in Parkinson's
disease. Hum. Mol. Genet. 23, 831-841 (2014)
Nalls, M.A., Escott-Price, V., Williams, N.M., Lubbe, S., Keller, M.F., Morris, H.R., Singleton, A.B.°,
International Parkinson's Disease Genomics Consortium (IPDGC) (Illig, T., Lichtner, P.): Genetic risk and
age in Parkinson's disease: Continuum not stratum. Mov. Disord. 30, 850-854 (2015)
NCD Risk Factors Collaboration (Müller-Nurasyid, M., Peters, A., Stöckl, D., Ezzati, M.°): Effects of
diabetes definition on global surveillance of diabetes prevalence and diagnosis: A pooled analysis of 96
population-based studies with 331 288 participants. Lancet Diabet. Endocrinol. 3, 624-637 (2015)
page 56 of 213
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#
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° corresponding authors
HMGU authors are given in bold letters
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Nead, K.T., Li, A., Wehner, M.R., Neupane, B., Gustafsson, S., Butterworth, A.S., Engert, J.C., Davis, A.D.,
Hegele, R.A., Miller, R., den Hoed, M., Khaw, K.T., Kilpeläinen, T.O., Wareham, N.J., Edwards, T.L.,
Hallmans, G., Varga, T.V., Kardia, S.L., Smith, J.A., Zhao, W., Faul, J.D., Weir, D.R., Mi, J., Xi, B.,
Quinteros, S.C., Cooper, C., Sayer, A.A., Jameson, K., Grøntved, A., Fornage, M., Sidney, S., Hanis, C.L.,
Highland, H.M., Häring, H.-U., Heni, M., Lasky-Su, J., Weiss, S.T., Gerhard, G.S., Still, C., Melka, M.M.,
Pausova, Z., Paus, T., Grant, S.F.A., Hakonarson, H., Price, R.A., Wang, K., Scherag, A., Hebebrand, J.,
Hinney, A., BIoBank Japan (Meyre, D.°), AGEN-BMI, GIANT Consortium (Albrecht, E., Gieger, C., Grallert,
H., Heid, I.M., Illig, T., Müller-Nurasyid, M., Peters, A., Thorand, B., Wichmann, H.-E.), Franks, P.W.,
Frayling, T.M., McCarthy, M.I., Hirschhorn, J.N., Loos, R.J., Ingelsson, E., Gerstein, H.C., Yusuf, S., Beyene,
J., Anand, S.S.: Contribution of common non-synonymous variants in PCSK1 to body mass index variation
and risk of obesity: A systematic review and meta-analysis with evidence from up to 331 175 individuals.
Hum. Mol. Genet. 24, 3582-3594 (2015)
Nelson, C.P., Hamby, S.E., Saleheen, D., Hopewell, J.C., Zeng, L., Assimes, T.L., Kanoni, S., Willenborg,
C., Burgess, S.L., Amouyel, P., Anand, S., Blankenberg, S., Boehm, B.O., Clarke, R.J., Collins, R.,
Dedoussis, G., Farrall, M., Franks, P.W., Groop, L., Hall, A.S., Hamsten, A., Hengstenberg, C., Hovingh,
G.K., Ingelsson, E., Kathiresan, S., Kee, F., Koenig, I.R., Kooner, J., Lehtimaeki, T., Maerz, W., McPherson,
R., Metspalu, A., Nieminen, M.S., O'Donnell, C.J., Palmer, C.N.A., Peters, A., Perola, M., Reilly, M.P.,
Ripatti, S., Roberts, R., Salomaa, V., Shah, S.H., Schreiber, S., Siegbahn, A., Thorsteinsdottir, U., Veronesi,
G., Wareham, N.J., Willer, C.J., Zalloua, P.A., Erdmann, J., Deloukas, P., Watkins, H., Schunkert, H.,
Danesh, J., Thompson, J.R., Samani, N.J.°, CARDIoGRAMplusC4D Consortium (Meisinger, C.): Genetically
determined height and coronary artery disease. N. Engl. J. Med. 372, 1608-1618 (2015)
Neth, K.°, Lucio, M., Walker, A., Zorn, J., Schmitt-Kopplin, P., Michalke, B.: Changes in brain
metallome/metabolome pattern due to a single i.v. injection of manganese in rats. PLoS ONE 10:e0138270
(2015)
Neth, K.°, Lucio, M., Walker, A., Kanawati, B., Zorn, J., Schmitt-Kopplin, P., Michalke, B.: Diverse
serum manganese species affect brain metabolites depending on exposure conditions. Chem. Res. Toxicol.
28, 1434-1442 (2015)
Ni, G., Strom, T.M., Pausch, H., Reimer, C., Preisinger, R., Simianer, H., Erbe, M.: Comparison among three
variant callers and assessment of the accuracy of imputation from SNP array data to whole-genome
sequence level in chicken. BMC Genomics 16:824 (2015)
Nimptsch, K.°, Janke, J., Pischon, T., Linseisen, J.: Association between dietary factors and plasma
fetuin-A concentrations in the general population. Br. J. Nutr. 114, 1278-1285 (2015)
page 57 of 213
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° corresponding authors
HMGU authors are given in bold letters
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Obeidat, M., Hao, K., Bossé, Y., Nickle, D.C., Nie, Y., Postma, D.S., Laviolette, M., Sandford, A.J., Daley,
D.D., Hogg, J.C., Elliott, W.M., Fishbane, N., Timens, W., Hysi, P.G., Kaprio, J., Wilson, J.F., Hui, J., Rawal,
R., Schulz, H., Stubbe, B., Hayward, C., Polasek, O., Jarvelin, M.R., Zhao, J.H., Jarvis, D., Kähönen, M.,
Franceschini, N., North, K.E., Loth, D.W., Brusselle, G.G., Smith, A.V., Gudnason, V., Bartz, T.M., Wilk, J.B.,
O'Connor, G.T., Cassano, P.A., Tang, W., Wain, L.V., Artigas, M.S., Gharib, S.A., Strachan, D.P., Sin, D.D.,
Tobin, M.D., London, S.J., Hall, I.P., Paré, P.D.°: Molecular mechanisms underlying variations in lung
function: A systems genetics analysis. Lancet Resp. Med. 3, 782-795 (2015)
Oehrle, B., Burgstaller, G., Irmler, M., Dehmel, S., Grün, J., Hwang, T., Krauss-Etschmann, S.,
Beckers, J., Meiners, S., Eickelberg, O.°: Validated prediction of pro-invasive growth factors using a
transcriptome-wide invasion signature derived from a complex 3D invasion assay. Sci. Rep. 5:12673 (2015)
Oksala, N.°, Pärssinen, J., Seppälä, I., Klopp, N., Illig, T., Laaksonen, R., Levula, M., Raitoharju, E.,
Kholova, I., Sioris, T., Kähönen, M., Lehtimäki, T., Hytönen, V.P.: Kindlin 3 (FERMT3) is associated with
unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins
in all major arterial beds. Atherosclerosis 242, 145-154 (2015)
Oláhová, M., Hardy, S.A., Hall, J., Yarham, J.W., Haack, T.B., Wilson, W.C., Alston, C.L., He, L., Aznauryan,
E., Brown, R.M., Brown, G.K., Morris, A.A., Mundy, H., Broomfield, A., Barbosa, I.A., Simpson, M.A.,
Deshpande, C., Moeslinger, D., Koch, J., Stettner, G.M., Bonnen, P.E., Prokisch, H., Lightowlers, R.N.,
McFarland, R., Chrzanowska-Lightowlers, Z.M., Taylor, R.W.°: LRPPRC mutations cause early-onset
multisystem mitochondrial disease outside of the French-Canadian population. Brain 138, 3503-3519 (2015)
Pappa, I., St Pourcain, B., Benke, K., Cavadino, A., Hakulinen, C., Nivard, M.G., Nolte, I.M., Tiesler, C.M.,
Bakermans-Kranenburg, M.J., Davies, G.E., Evans, D.M., Geoffroy, M.C., Grallert, H., Groen-Blokhuis,
M.M., Hudziak, J.J., Kemp, J.P., Keltikangas-Järvinen, L., McMahon, G., Mileva-Seitz, V.R., Motazedi, E.,
Power, C., Raitakari, O.T., Ring, S.M., Rivadeneira, F., Rodriguez, A., Scheet, P.A., Seppälä, I., Snieder, H.,
Standl, M., Thiering, E., Timpson, N.J., Veenstra, R., Velders, F.P., Whitehouse, A.J., Smith, G.D.,
Heinrich, J., Hyppönen, E., Lehtimäki, T., Middeldorp, C.M., Oldehinkel, A.J., Pennell, C.E., Boomsma, D.I.,
Tiemeier, H.°: A genome-wide approach to children's aggressive behavior: The EAGLE consortium. Am. J.
Med. Genet. B, DOI: 10.1002/ajmg.b.32333 (2015)
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Paternoster, L.°, Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D.P., Curtin, J.A., Bonnelykke,
K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A.C., Thyssen, J.P., den Dekker, H.T., Ferreira, M.A.,
Altmaier, E.M., Sleiman, P.M.A., Xiao, F.L., Gonzalez, J.R., Marenholz, I., Kalb, B., Pino-Yanes, M., Xu, C.,
Carstensen, L., Groen-Blokhuis, M.M., Venturini, C., Pennell, C.E., Barton, S.J., Levin, A.M., Curjuric, I.,
Bustamante, M., Kreiner-Moller, E., Lockett, G.A., Bacelis, J., Bunyavanich, S., Myers, R.A., Matanovic, A.,
Kumar, A., Tung, J.Y., Hirota, T., Kubo, M., McArdle, W.L., Henderson, A.J., Kemp, J.P., Zheng, J.H., Smith,
G.D., Rueschendorf, F., Bauerfeind, A., Lee-Kirsch, M.A., Arnold, A., Homuth, G., Schmidt, C.O., Mangold,
E., Cichon, S., Keil, T., Rodriguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Foelster-Holst, R.,
Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L.L., Grarup, N., de Jongste, J.C., Rivadeneira, F.,
Hofman, A., Jaddoe, V.W.V., Pasmans, S.G.M.A., Elbert, N.J., Uitterlinden, A.G., Marks, G.B., Thompson,
P.J., Matheson, M.C., Robertson, C.F., Ried, J.S., Li, J., Zuo, X.B., Zheng, X.D., Yin, X.Y., Sun, L.D.,
McAleer, M.A., O'Regan, G.M., Fahy, C.M.R., Campbell, L.E., Macek, M., Kurek, M., Hu, D., Eng, C.,
Postma, D.S., Feenstra, B., Geller, F., Hottenga, J.J., Middeldorp, C.M., Hysi, P., Bataille, V., Spector, T.,
Tiesler, C.M., Thiering, E., Pahukasahasram, B., Yang, J.J., Imboden, M., Huntsman, S., Vilor-Tejedor, N.,
Relton, C.L., Myhre, R., Nystad, W., Custovic, A., Weiss, S.T., Meyers, D.A., Soederhaell, C., Melén, E.,
Ober, C., Raby, B.A., Simpson, A., Jacobsson, B., Holloway, J.W., Bisgaard, H., Sunyer, J., Probst-Hensch,
N.M., Williams, L.K., Godfrey, K.M., Wang, C.A., Boomsma, D.I., Melbye, M., Koppelman, G.H., Jarvis, D.,
McLean, W.H.I., Irvine, A.D., Zhang, X.J., Hakonarson, H., Gieger, C., Burchard, E.G., Martin, N.G., Duijts,
L., Linneberg, A., Jarvelin, M.R., Nöthen, M.M., Lau, S., Huebner, N., Lee, Y., Tamari, M., Hinds, D.A.,
Glass, D., Brown, S.J., Heinrich, J., Evans, D.M., Weidinger, S., Australian Asthma Genetics Consortium
(AAGC), EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium: Multi-ancestry
genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic
dermatitis. Nat. Genet. 47, 1449-1456 (2015)
Pedata, P., Stöger, T.°, Zimmermann, R., Peters, A., Oberdörster, G., D'Anna, A.: "Are we forgetting the
smallest, sub 10 nm combustion generated particles?" Part. Fibre Toxicol. 12:34 (2015)
Perez, L.°, Wolf, K., Hennig, F., Penell, J., Basagana, X., Aguilera, I., Agis, D., Beelen, R., Brunekreef, B.,
Cyrys, J., Fuks, K.B., Adam, M., Baldassare, D., Cirach, M., Elosua, R., Dratva, J., Hampel, R., Koenig, W.,
Marrugat, J., de Faire, U., Pershagen, G., Probst-Hensch, N.M., de Nazelle, A., Nieuwenhuijsen, M.J.,
Rathmann, W., Rivera, M., Seissler, J., Schindler, C., Thierry, J., Hoffmann, B., Peters, A., Künzli, N.: Air
pollution and atherosclerosis: A cross-sectional analysis of four European cohort studies in the ESCAPE
study. Environ. Health Perspect. 123, 597-605 (2015)
Pers, T.H., Karjalainen, J.M., Chan, Y., Westra, H.J., Wood, A.R., Yang, J., Lui, J.C., Vedantam, S.,
Gustafsson, S., Esko, T., Frayling, T., Speliotes, E.K., GIANT Consortium (Albrecht, E., Gieger, C.,
Grallert, H., Heid, I.M., Illig, T., Müller-Nurasyid, M., Peters, A., Thorand, B., Wichmann, H.-E.),
Boehnke, M., Raychaudhuri, S., Fehrmann, R.S.N., Hirschhorn, J.N.°, Franke, L.°: Biological interpretation of
genome-wide association studies using predicted gene functions. Nat. Commun. 6:5890 (2015)
Pessi, T.°, Viiri, L.E., Raitoharju, E., Astola, N., Seppälä, I., Waldenberger, M., Lounatmaa, K., Davies, A.H.,
Lehtimäki, T., Karhunen, P.J., Monaco, C.: Interleukin-6 and microRNA profiles induced by oral bacteria in
human atheroma derived and healthy smooth muscle cells. SpringerPlus 4:206 (2015)
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Peters, A.°, Hampel, R., Cyrys, J., Breitner, S., Geruschkat, U., Kraus, U., Zareba, W., Schneider, A.E.:
Elevated particle number concentrations induce immediate changes in heart rate variability: A panel study in
individuals with impaired glucose metabolism or diabetes. Part. Fibre Toxicol. 12:7 (2015)
Peters, M.J., Joehanes, R., Pilling, L.C., Schurmann, C., Conneely, K.N., Powell, J., Reinmaa, E., Sutphin,
G.L., Zhernakova, A., Schramm, K., Wilson, Y.A., Kobes, S., Tukiainen, T., Ramos, Y.F., Göring, H.H.H.,
Fornage, M., Liu, Y., Gharib, S.A., Stranger, B.E., de Jager, P.L., Aviv, A., Levy, D., Murabito, J.M., Munson,
P.J., Huan, T., Hofman, A., Uitterlinden, A.G., Rivadeneira, F., van Rooij, J., Stolk, L., Broer, L., Verbiest,
M.M.P.J., Jhamai, M., Arp, P., Metspalu, A., Tserel, L., Milani, L., Samani, N.J., Peterson, P., Kasela, S.,
Codd, V., Peters, A., Ward-Caviness, C.K., Herder, C., Waldenberger, M., Roden, M., Singmann, P.,
Zeilinger, S., Illig, T., Homuth, G., Grabe, H.J., Völzke, H., Steil, L., Kocher, T., Martin, N.G., Smith, A.K.,
Mehta, D., Binder, E.B., Nylocks, K.M., Kennedy, E.M., Klengel, T., Ding, J., Suchy-Dicey, A., Enquobahrie,
D.A., Houwing-Duistermaat, J.J., Slagboom, P.E., Helmer, Q., den Hollander, W., Raj, T., Oyston, L.J.,
Turner, S.T., Blangero, J., Brody, J., Rotter, J.I., Chen, Y.D., Kloppenburg, M., Bean, S., Bakhshi, N., Wang,
Q.P., Psaty, B.M., Tracy, R.P., Montgomery, G.W., Meulenbelt, I., Ressler, K.J., Yang, J., Franke, L.,
Kettunen, J., Visscher, P.M., Neely, G.G., Korstanje, R., Hanson, R.L., Prokisch, H., Ferrucci, L., Esko, T.,
Teumer, A., van Meurs, J.B.°, Johnson, A.D.°: The transcriptional landscape of age in human peripheral
blood. Nat. Commun. 6:8570 (2015)
Peyrot, W.J.°, Lee, S.H., Milaneschi, Y., Abdellaoui, A., Byrne, E.M., Esko, T., de Geus, E.J., Hemani, G.,
Hottenga, J.J., Kloiber, S., Levinson, D.F., Lucae, S., Psychiatric GWAS Consortium Major Depressive
Disorder Working Group (Wray, N.R.), Martin, N.G., Medland, S.E., Metspalu, A., Milani, L., Noethen, M.M.,
Potash, J.B., Rietschel, M., Rietveld, C.A., Ripke, S., Shi, J., Social Science Genetic Association Consortium
(Gieger, C., Holle, R., Illig, T., Lichtner, P., Mielck, A., Wichmann, H.-E.), Willemsen, G., Zhu, Z.,
Boomsma, D.I., Penninx, B.: The association between lower educational attainment and depression owing to
shared genetic effects? Results in ~25 000 subjects. Mol. Psychiatry 20, 735-743 (2015)
Pfeiffer, L., Wahl, S., Pilling, L.C., Reischl, E., Sandling, J.K., Kunze, S., Holdt, L.M., Kretschmer, A.,
Schramm, K., Adamski, J., Klopp, N., Illig, T., Hedman, A.K., Roden, M., Hernandez, D.G., Singleton, A.B.,
Thasler, W.E., Grallert, H., Gieger, C., Herder, C., Teupser, D., Meisinger, C., Spector, T.D., Kronenberg,
F., Prokisch, H., Melzer, D., Peters, A., Deloukas, P., Ferrucci, L., Waldenberger, M.°: DNA methylation of
lipid-related genes affects blood lipid levels. Circ. Cardiovasc. Genet. 8, 334-342 (2015)
Pfluger, P.T., Kabra, D.G., Aichler, M., Schriever, S.C., Pfuhlmann, K., Casquero García, V., Lehti, M.,
Weber, J., Kutschke, M., Rozman, J., Elrod, J.W., Hevener, A.L., Feuchtinger, A., Hrabě de Angelis, M.,
Walch, A.K., Rollmann, S.M., Aronow, B.J., Müller, T.D., Perez-Tilve, D., Jastroch, M., de Luca, M.,
Molkentin, J.D., Tschöp, M.H.°: Calcineurin links mitochondrial elongation with energy metabolism. Cell
Metab. 22, 838-850 (2015)
Picciotto, S.°, Peters, A., Eisen, E.A.: Hypothetical exposure limits for oil-based metalworking fluids and
cardiovascular mortality in a cohort of autoworkers: Structural accelerated failure time models in a public
health framework. Am. J. Epidemiol. 181, 563-570 (2015)
page 60 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Pilecki, B., Schlosser, A., Wulf-Johansson, H., Trian, T., Moeller, J.B., Marcussen, N., Aguilar-Pimentel,
J.A., Hrabě de Angelis, M., Vestbo, J., Berger, P., Holmskov, U., Sorensen, G.L.°: Microfibrillar-associated
protein 4 modulates airway smooth muscle cell phenotype in experimental asthma. Thorax 70, 862-872
(2015)
Pirovano, A.°, Brandmaier, S., Huijbregts, M.A., Ragas, A.M., Veltman, K., Hendriks, A.J.: The utilisation of
structural descriptors to predict metabolic constants of xenobiotics in mammals. Environ. Toxicol. Pharmacol.
39, 247-258 (2015)
Pivovarova, O.°, von Loeffelholz, C., Ilkavets, I., Sticht, C., Zhuk, S., Murahovschi, V., Lukowski, S., Döcke,
S., Kriebel, J., de Las Heras Gala, T., Malashicheva, A., Kostareva, A., Lock, J.F., Stockmann, M., Grallert,
H., Gretz, N., Dooley, S., Pfeiffer, A.F., Rudovich, N.N.: Modulation of insulin degrading enzyme activity and
liver cell proliferation. Cell Cycle 14, 2293-2300 (2015)
Poos, K.#, Smida, J.#, Maugg, D., Eckstein, G.N., Baumhoer, D., Nathrath, M., Korsching, E.°: Genomic
heterogeneity of osteosarcoma - shift from single candidates to functional modules. PLoS ONE 10:e0123082
(2015)
Porta, A.°, Girardengo, G., Bari, V., George, A.L. Jr., Brink, P.A., Goosen, A., Crotti, L., Schwartz, P.J.:
Autonomic control of heart rate and QT interval variability influences arrhythmic risk in long QT syndrome
type 1. J. Am. Coll. Cardiol. 65, 367-374 (2015)
Powell, C.A., Kopajtich, R., D'Souza, A.R., Rorbach, J., Kremer, L.S., Husain, R.A., Dallabona, C., Donnini,
C., Alston, C.L., Griffin, H., Pyle, A., Chinnery, P.F., Strom, T.M., Meitinger, T., Rodenburg, R.J.,
Schottmann, G., Schuelke, M., Romain, N., Haller, R.G., Ferrero, I., Haack, T.B., Taylor, R.W., Prokisch,
H.°, Minczuk, M.°: TRMT5 mutations cause a defect in post-transcriptional modification of mitochondrial
tRNA associated with multiple respiratory-chain deficiencies. Am. J. Hum. Genet. 97, 319-328 (2015)
Prokisch, H.°, Sperl, W., Meitinger, T., Mayr, J.A.: Mitochondriopathien – neue Trends in Diagnostik und
Therapie. Med. Genet. 27, 282-287 (2015)
Qanbari, S., Seidel, M., Strom, T.M., Mayer, K.F.X., Preisinger, R., Simianer, H.: Parallel selection revealed
by population sequencing in chicken. Genome Biol. Evol. 7, 3299-3306 (2015)
Quante, A.S., Herz, J., Whittemore, A.S., Fischer, C., Strauch, K., Terry, M.B.°: Assessing absolute
changes in breast cancer risk due to modifiable risk factors. Breast Cancer Res. Treat. 152, 193-197 (2015)
Quante, A.S., Whittemore, A.S., Shriver, T., Hopper, J.L., Strauch, K., Terry, M.B.°: Practical problems with
clinical guidelines for breast cancer prevention based on remaining lifetime risk. J. Natl. Cancer Inst.
107:djv124 (2015)
Quinones, P.A.°, Kirchberger, I.°, Amann, U.°, Heier, M.°, Kuch, B.°, von Scheidt, W.°, Meisinger, C.°:
Does marital status contribute to the explanation of the hypercholesterolemia paradox in relation to long term
mortality in myocardial infarction? Findings from the MONICA/KORA Myocardial Infarction Registry. Prev.
Med. 75, 25-31 (2015)
page 61 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Raffler, J., Friedrich, N., Arnold, M., Kacprowski, T., Rueedi, R., Altmaier, E.M., Bergmann, S., Budde, K.,
Gieger, C., Homuth, G., Pietzner, M., Römisch-Margl, W., Strauch, K., Völzke, H., Waldenberger, M.,
Wallaschofski, H., Nauck, M., Völker, U., Kastenmüller, G.°, Suhre, K.: Genome-wide association study
with targeted and non-targeted NMR metabolomics identifies 15 novel loci of urinary human metabolic
individuality. PLoS Genet. 11:e1005487 (2015)
Rahmioglu, N., Macgregor, S., Drong, A.W., Hedman, A.K., Harris, H.R., Randall, J.C., Prokopenko, I.,
International Endogene Consortium (IEC) (Zondervan, K.T.°), GIANT Consortium (Albrecht, E., Gieger, C.,
Grallert, H., Heid, I.M., Illig, T., Müller-Nurasyid, M., Peters, A., Thorand, B., Wichmann, H.-E.), Nyholt,
D.R., Morris, A.P., Montgomery, G.W., Missmer, S.A., Lindgren, C.M.: Genome-wide enrichment analysis
between endometriosis and obesity-related traits reveals novel susceptibility loci. Hum. Mol. Genet. 24,
1185-1199 (2015)
Rathkolb, B.°, Klempt, M., Sabrautzki, S., Michel, D., Klaften, M., Laufs, J., Sedlmeier, R., Hans, W.,
Fuchs, H., Muckenthaler, M.U., Horsch, M., Campagna, D.R., Fleming, M., Hrabě de Angelis, M., Wolf, E.,
Aigner, B.: Screen for alterations of iron related parameters in N-ethyl-N-nitrosurea-treated mice identified
mutant lines with increased plasma ferritin levels. Biometals 28, 293-306 (2015)
Rautanen, A.°, Mills, T.C., Gordon, A.C., Hutton, P., Steffens, M., Nuamah, R.A., Chiche, J.D., Parks, T.L.,
Chapman, S.J., Davenport, E.E., Elliott, K.S., Bion, J.F., Lichtner, P., Meitinger, T., Wienker, T.F., Caulfield,
M.J., Mein, C., Bloos, F.M., Bobek, I., Cotogni, P., Sramek, V., Sarapuu, S., Kobilay, M., Ranieri, V.M., Rello,
J., Sirgo, G., Weiss, Y.G., Russwurm, S., Schneider, E.M., Reinhart, K., Holloway, P.A.H., Knight, J.C.,
Garrard, C.S., Russell, J.A., Walley, K.R., Stüber, F., Hill, A.V.S., Hinds, C.: Genome-wide association study
of survival from sepsis due to pneumonia: An observational cohort study. Lancet Resp. Med. 3, 53-60 (2014)
Rohrmann, S., Linseisen, J.: Processed
10.1017/S0029665115004255 (2015)
meat:
The
real
villain?
Proc.
Nutr.
Soc.,
DOI:
Rosen, B., Schick, J., Wurst, W.°: Beyond knockouts: The International Knockout Mouse Consortium
delivers modular and evolving tools for investigating mammalian genes. Mamm. Genome 26, 456-466 (2015)
Rosenberger, A.°, Friedrichs, S., Amos, C.I., Brennan, P., Fehringer, G., Heinrich, J., Hung, R.J., Muley,
T.R., Müller-Nurasyid, M., Risch, A., Bickeböller, H.: META-GSA: Combining findings from gene-set
analyses across several genome-wide association studies. PLoS ONE 10:e0140179 (2015)
Ross, S., D'Mello, M., Anand, S.S., Eikelboom, J., CARDIoGRAMplusC4D Consortium (Gieger, C.,
Meitinger, T., Peters, A.), Stewart, A.F.R., Samani, N.J., Roberts, R., Paré, G.°: Effect of bile acid
sequestrants on the risk of cardiovascular events: A mendelian randomization analysis. Circ. Cardiovasc.
Genet. 8, 618-627 (2015)
page 62 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Rothwell, S.°, Cooper, R.G., Lundberg, I.E., Miller, F.W., Gregersen, P.K., Bowes, J., Vencovsky, J., Danko,
K., Limaye, V., Selva-O'Callaghan, A., Hanna, M.G., Machado, P.M., Pachman, L.M., Reed, A.M., Rider,
L.G., Cobb, J., Platt, H., Molberg, O., Benveniste, O., Mathiesen, P., Radstake, T., Doria, A., de Bleecker, J.,
de Paepe, B., Maurer, B., Ollier, W.E., Padyukov, L., O'Hanlon, T.P., Lee, A., Amos, C.I., Gieger, C.,
Meitinger, T., Winkelmann, J., Wedderburn, L.R., Chinoy, H., Lamb, J.A.: Dense genotyping of
immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk
factor and suggests different genetic background for major clinical subgroups. Ann. Rheum. Dis., DOI:
10.1136/annrheumdis-2015-208119 (2015)
Rottenkolber, M.#, Ferrari, U.#, Holland, L., Aertsen, S., Kammer, N.N., Hetterich, H., Fugmann, M.,
Banning, F., Weise, M., Sacco, V., Kohn, D., Freibothe, I., Hutter, S., Hasbargen, U., Lehmann, R.,
Grallert, H., Parhofer, K.G., Seissler, J., Lechner, A.°: The diabetes risk phenotype of young women with
recent gestational diabetes. J. Clin. Endocrinol. Metab. 100, E910-E918 (2015)
Rozman, J., Rathkolb, B., Neschen, S., Fuchs, H., Gailus-Durner, V., Klingenspor, M., Wolf, E., Hrabě de
Angelis, M.°: Glucose tolerance tests for systematic screening of glucose homeostasis in mice. Curr. Protoc.
Mouse Biol. 5, 65-84 (2015)
Rückert, I.-M.°, Baumert, J.J., Schunk, M., Holle, R., Schipf, S., Völzke, H., Kluttig, A., Greiser, K.H.,
Tamayo, T., Rathmann, W., Meisinger, C.: Blood pressure control has improved in people with and without
type 2 diabetes but remains suboptimal: A longitudinal study based on the German DIAB-CORE consortium.
PLoS ONE 10:e0133493 (2015)
Rückert, I.-M., Icks, A., Baechle, C., Meisinger, C.°: Versorgung bei Diabetes - Zielerreichung, regionale,
sozioökonomische Unterschiede. Diabetes Stoffwechs. Herz 23, 356-361 (2014)
Saarikangas, J.°, Kourdougli, N., Senju, Y., Chazal, G., Segerstrale, M., Minkeviciene, R., Kuurne, J.,
Mattila, P.K., Garrett, L., Hölter, S.M., Becker, L., Rácz, I., Hans, W., Klopstock, T., Wurst, W., Zimmer, A.,
Fuchs, H., Gailus-Durner, V., Hrabě de Angelis, M., von Ossowski, L., Taira, T., Lappalainen, P., Rivera,
C.°, Hotulainen, P.°: MIM-induced membrane bending promotes dendritic spine initiation. Dev. Cell 33,
644-659 (2015)
#
#
#
Scavizzi, F. , Ryder, E. , Newman, S. , Raspa, M., Gleeson, D., Wardle-Jones, H., Montoliu, L., Fernandez,
A., Dessain, M.-L., Larrigaldie, V., Khorshidi, Z., Voulteenaho, R., Soininen, R., André, P., Jacquot, S.,
#
Hong, Y., Hrabě de Angelis, M., Ramirez-Solis, R., Doe, B. °: Blastocyst genotyping for quality control of
mouse mutant archives: An ethical and economical approach. Transgenic Res. 24, 921-927 (2015)
Schaarschmidt, H., Ellinghaus, D., Rodriguez, E., Kretschmer, A., Baurecht, H., Lipinski, S., Meyer-Hoffert,
U., Harder, J., Lieb, W., Novak, N., Fölster-Holst, R., Esparza-Gordillo, J., Marenholz, I., Ruschendorf, F.,
Hubner, N., Reischl, E., Waldenberger, M., Gieger, C., Illig, T., Kabesch, M., Zhang, X.J., Xiao, F.L., Lee,
Y.A., Franke, A., Weidinger, S.°: A genome-wide association study reveals 2 new susceptibility loci for atopic
dermatitis.ϖ J. Allergy Clin. Immunol. 136, 802-806 (2015)
page 63 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Schäfer, A., Neschen, S., Kahle, M., Sarioglu, H., Gaisbauer, T., Imhof, A., Adamski, J., Hauck, S.M.°,
Ueffing, M.: The epoxyeicosatrienoic acid pathway enhances hepatic insulin signaling and is repressed in
insulin-resistant mouse liver. Mol. Cell. Proteomics 14, 2764-2774 (2015)
Schedel, M., Michel, S., Gaertner, V.D., Toncheva, A.A., Depner, M., Binia, A., Schieck, M., Rieger, M.T.,
Klopp, N., von Berg, A., Bufe, A., Laub, O., Rietschel, E., Heinzmann, A., Simma, B., Vogelberg, C.,
Genuneit, J., Illig, T., Kabesch, M.°: Polymorphisms related to ORMDL3 are associated with asthma
susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels. J.
Allergy Clin. Immunol. 136, 893-903 (2015)
Scheler, M., Hrabě de Angelis, M., Al-Hasani, H., Häring, H.-U., Weigert, C.°, Lehr, S.: Methods for
proteomics-based analysis of the human muscle secretome using an in vitro exercise model. Methods Mol.
Biol. 1295, 55-64 (2015)
Schiff, M.°, Haberberger, B., Xia, C.P., Mohsen, A.W., Goetzman, E.S., Wang, Y., Uppala, R., Zhang, Y.,
Karunanidhi, A., Prabhu, D., Alharbi, H., Prochownik, E.V., Haack, T.B., Häberle, J., Munnich, A., Rotig, A.,
Taylor, R.W., Nicholls, R.D., Kim, J.J., Prokisch, H., Vockley, J.°: Complex I assembly function and fatty
acid oxidation enzyme activity of ACAD9 both contribute to disease severity in ACAD9 deficiency. Hum. Mol.
Genet. 24, 3238-3247 (2015)
Schiller, H.°, Fernandez, I.E., Burgstaller, G., Schaab, C., Scheltema, R.A., Schwarzmayr, T., Strom,
T.M., Eickelberg, O.°, Mann, M.°: Time- and compartment-resolved proteome profiling of the extracellular
niche in lung injury and repair. Mol. Syst. Biol. 11:819 (2015)
Schlosser, A.#, Pilecki, B.#, Hemstra, L.E., Kejling, K., Kristmannsdottir, G.B., Wulf-Johansson, H., Moeller,
J.B., Füchtbauer, E.M., Nielsen, O., Kirketerp-Møller, K., Dubey, L.K., Hansen, P.B., Stubbe, J., Wrede, C.,
Hegermann, J., Ochs, M., Rathkolb, B., Schrewe, A., Bekeredjian, R., Wolf, E., Gailus-Durner, V., Fuchs,
H., Hrabě de Angelis, M., Lindholt, J.S., Holmskov, U., Sorensen, G.L.°: MFAP4 promotes vascular smooth
muscle migration, proliferation and accelerates neointima formation. Arterioscler. Thromb. Vasc. Biol. 36,
122-133 (2015)
Schmidt, J., Panzilius, E., Bartsch, H.S., Irmler, M., Beckers, J., Kari, V., Linnemann, J., Dragoi, D.,
Hirschi, B., Kloos, U., Sass, S., Theis, F.J., Kahlert, S., Johnsen, S.A., Sotlar, K., Scheel, C.°:
Stem-cell-like properties and epithelial plasticity arise as stable traits after transient Twist1 activation. Cell
Rep. 10, 131-139 (2015)
Schmitt, J.°, Schwarz, K., Baurecht, H., Hotze, M., Fölster-Holst, R., Rodriguez, E., Lee, Y.A., Franke, A.,
Degenhardt, F., Lieb, W., Gieger, C., Kabesch, M., Nöthen, M.M., Irvine, A.D., McLean, W.H., Deckert, S.,
Stephan, V., Schwarz, P., Aringer, M., Novak, N., Weidinger, S.: Atopic dermatitis is associated with an
increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1
diabetes. J. Allergy Clin. Immunol. 137, 130–136 (2016) [published online 2015]
page 64 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Schmitt, S., Eberhagen, C., Weber, S., Aichler, M., Zischka, H.°: Isolation of mitochondria from cultured
cells and liver tissue biopsies for molecular and biochemical analyses. Methods Mol. Biol. 1295, 87-97
(2015)
Schulte, E.C., Fukumori, A., Mollenhauer, B., Hor, H., Arzberger, T., Perneczky, R., Kurz, A., Diehl-Schmid,
J., Hüll, M., Lichtner, P., Eckstein, G.N., Zimprich, A., Haubenberger, D., Pirker, W., Brücke, T., Bereznai,
B., Molnar, M.J., Lorenzo-Betancor, O., Pastor, P., Peters, A., Gieger, C., Estivill, X., Meitinger, T.,
Kretzschmar, H.A., Trenkwalder, C., Haass, C., Winkelmann, J.°: Rare variants in β-Amyloid Precursor
Protein (APP) and Parkinson's disease. Eur. J. Hum. Genet. 23, 1328-1333 (2015)
Schunk, M., Reitmeir, P., Schipf, S., Völzke, H., Meisinger, C., Ladwig, K.-H., Kluttig, A., Greiser, K.H.,
Berger, K.U., Müller, G., Ellert, U., Neuhauser, H., Tamayo, T., Rathmann, W., Holle, R.°: Health-related
quality of life in women and men with type 2 diabetes: A comparison across treatment groups. J. Diab.
Complic. 29, 203-211 (2015)
Schunk, M.°, Stark, R.G., Reitmeir, P., Meisinger, C., Holle, R.: Towards patient-oriented diabetes care:
Results from two KORA surveys in Southern Germany: J. Diabetes Res. 2015:368570 (2015)
Schwab, S., Zierer, A., Heier, M., Fischer, B., Huth, C., Baumert, J.J., Meisinger, C., Peters, A.,
Thorand, B.°: Intake of vitamin and mineral supplements and longitudinal association with HbA1c levels in
the general non-diabetic population - results from the MONICA/KORA S3/F3 study. PLoS ONE 10:e0139244
(2015)
Schwab, S., Zierer, A., Schneider, A.E., Heier, M., Koenig, W., Kastenmüller, G., Waldenberger, M.,
Peters, A., Thorand, B.°: Vitamin E supplementation is associated with lower levels of C-reactive protein
only in higher dosages and combined with other antioxidants: The Cooperative Health Research in the
Region of Augsburg (KORA) F4 study. Br. J. Nutr. 113, 1782-1791 (2015)
Schwenk, R., Hrabě de Angelis, M., Beckers, J.: Epigenetische Vererbung - ist die Zukunft diabetisch?
Diabetes akt. 13, 72-74 (2015)
Seco, C.Z.#, Giese, A.P.#, Shafique, S.#, Schraders, M., Oonk, A.M.M., Grossheim, M., Oostrik, J., Strom,
T.M., Hegde, R., van Wijk, E., Frolenkov, G.I., Azam, M., Yntema, H.G., Free, R.H., Riazuddin, S., Verheij,
J.B., Admiraal, R.J., Qamar, R., Ahmed, Z.M., Kremer, H.°: Novel and recurrent CIB2 variants, associated
with nonsyndromic deafness, do not affect calcium buffering and localization in hair cells. Eur. J. Hum.
Genet. 24, 542-549 (2016) [published online 2015]
Segrè, A.V., Wei, N., DIAGRAM Consortium (Florez, J.C.°, Klopp, N., Illig, T., Müller-Nurasyid, M., Peters,
A.): Pathways targeted by antidiabetes drugs are enriched for multiple genes associated with type 2 diabetes
risk. Diabetes 64, 1470-1483 (2015)
page 65 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Sekula, P., Goek, O.N., Quaye, L., Barrios, C., Levey, A.S., Römisch-Margl, W., Menni, C., Yet, I., Gieger,
C., Inker, L.A., Adamski, J., Gronwald, W., Illig, T., Dettmer, K., Krumsiek, J., Oefner, P.J., Valdes, A.M.,
Meisinger, C., Coresh, J., Spector, T.D., Mohney, R.P., Suhre, K., Kastenmüller, G.°, Köttgen, A.°: A
metabolome-wide association study of kidney function and disease in the general population. J. Am. Soc.
Nephrol. 27, 1175-1188 (2016) [published online 2015]
Shin, J.T.#, Bourdon, C.#, Bernard, M., Wilson, M., Reischl, E., Waldenberger, M., Ruggeri, B., Schumann,
G., Desrivières, S., Leemans, A., Abrahamowicz, M., Leonard, G.T., Richer, L., Bouchard, L., Gaudet, D.,
Paus, T., Pausova, Z.°: Layered genetic control of DNA methylation and gene expression: A locus of multiple
sclerosis in healthy individuals. Hum. Mol. Genet. 24, 5733-5745 (2015)
page 66 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Shungin, D., Winkler, T.W., Croteau-Chonka, D.C., Ferreira, T., Locke, A.E., Mägi, R., Strawbridge, R.J.,
Pers, T.H., Fischer, K., Justice, A.E., Workalemahu, T., Wu, J.M., Buchkovich, M.L., Heard-Costa, N.L.,
Roman, T.S., Drong, A.W., Song, C., Gustafsson, S., Day, F.R., Esko, T., Fall, T., Kutalik, Z., Luan, J.,
Randall, J.C., Scherag, A., Vedantam, S., Wood, A.R., Chen, J., Fehrmann, R.S.N., Karjalainen, J., Kahali,
B., Liu, C.T., Schmidt, E.M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bragg-Gresham, J.L.,
Buyske, S., Demirkan, A., Ehret, G.B., Feitosa, M.F., Goel, A., Jackson, A.U., Johnson, T., Kleber, M.E.,
Kristiansson, K., Mangino, M., Mateo Leach, I., Medina-Gomez, C., Palmer, C.D., Pasko, D., Pechlivanis, S.,
Peters, M.J., Prokopenko, I., Stancáková, A., Ju Sung, Y., Tanaka, T., Teumer, A., van Vliet-Ostaptchouk,
J.V., Yengo, L., Zhang, W., Albrecht, E., Ärnlöv, J., Arscott, G.M., Bandinelli, S., Barrett, A., Bellis, C.,
Bennett, A.J., Berne, C., Blüher, M., Böhringer, S., Bonnet, F., Böttcher, Y., Bruinenberg, M., Carba, D.B.,
Caspersen, I.H., Clarke, R., Daw, E.W., Deelen, J., Deelman, E., Delgado, G., Doney, A.S., Eklund, N.,
Erdos, M.R., Estrada, K., Eury, E., Friedrich, N., Garcia, M.E., Giedraitis, V., Gigante, B., Go, A.S., Golay, A.,
Grallert, H., Grammer, T.B., Gräßler, J., Grewal, J., Groves, C.J., Haller, T., Hallmans, G., Hartman, C.A.,
Hassinen, M., Hayward, C., Heikkilä, K., Herzig, K.H., Helmer, Q., Hillege, H.L., Holmen, O.L., Hunt, S.C.,
Isaacs, A., Ittermann, T., James, A.L., Johansson, I., Juliusdottir, T., Kalafati, I.P., Kinnunen, L., Koenig, W.,
Kooner, I.K., Kratzer, W., Lamina, C., Leander, K., Lee, N.R., Lichtner, P., Lind, L., Lindstrom, J., Lobbens,
S., Lorentzon, M., Mach, F., Magnusson, P.K., Mahajan, A., McArdle, W.L., Menni, C., Merger, S., Mihailov,
E., Milani, L., Mills, R., Moayyeri, A., Monda, K.L., Mooijaart, S.P., Mühleisen, T.W., Mulas, A., Müller, G.,
Müller-Nurasyid, M., Nagaraja, R., Nalls, M.A., Narisu, N., Glorioso, N., Nolte, I.M., Olden, M., Rayner,
N.W., Renström, F., Ried, J.S., Robertson, N.R., Rose, L.M., Sanna, S., Scharnagl, H., Scholtens, S.,
Sennblad, B., Seufferlein, T., Sitlani, C.M., Smith, A.V., Stirrups, K., Stringham, H.M., Sundström, J., Swertz,
M.A., Swift, A.J., Syvanen, A.C., Tayo, B.O., Thorand, B., Thorleifsson, G., Tomaschitz, A., Troffa, C., van
Oort, F.V., Verweij, N., Vonk, J.M., Waite, L.L., Wennauer, R., Wilsgaard, T., Wojczynski, M.K., Wong, A.,
Zhang, Q., Hua Zhao, J., Brennan, E.P., Choi, M., Eriksson, P., Folkersen, L., Franco-Cereceda, A., Gharavi,
A.G., Hedman, A.K., Hivert, M.F., Huang, J., Kanoni, S., Karpe, F., Keildson, S., Kiryluk, K., Liang, L., Lifton,
R.P., Ma, B., McKnight, A.J., McPherson, R., Metspalu, A., Min, J.L., Moffatt, M.F., Montgomery, G.W.,
Murabito, J.M., Nicholson, G., Nyholt, D.R., Olsson, C., Perry, J.R., Reinmaa, E., Salem, R.M., Sandholm,
N., Schadt, E.E., Scott, R.A., Stolk, L., Vallejo, E.E., Westra, H.J., Zondervan, K.T., Amouyel, P., Arveiler, D.,
Bakker, S.J., Beilby, J., Bergman, R.N., Blangero, J., Brown, M.J., Burnier, M., Campbell, H., Chakravarti, A.,
Chines, P.S., Claudi-Boehm, S., Collins, F.S., Crawford, D.C., Danesh, J., de Faire, U., de Geus, E.J., Dörr,
M., Erbel, R., Eriksson, J.G., Farrall, M., Ferrannini, E., Ferrieres, J., Forouhi, N.G., Forrester, T., Franco,
O.H., Gansevoort, R.T., Gieger, C., Gudnason, V., Haiman, C.A., Harris, T.B., Hattersley, A.T., Heliövaara,
M., Hicks, A.A., Hingorani, A.D., Hoffmann, W., Hofman, A., Homuth, G., Humphries, S.E., Hyppönen, E.,
Illig, T., Jarvelin, M.R., Johansen, B., Jousilahti, P., Jula, A.M., Kaprio, J., Kee, F., Keinanen-Kiukaanniemi,
S.M., Kooner, J.S., Kooperberg, C., Kovacs, P., Kraja, A.T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Lakka,
T.A., Langenberg, C., Le Marchand, L., Lehtimäki, T., Lyssenko, V., Männisto, S., Marette, A., Matise, T.C.,
McKenzie, C.A., McKnight, B., Musk, A.W., Möhlenkamp, S., Morris, A.D., Nelis, M., Ohlsson, C., Oldehinkel,
A.J., Ong, K.K., Palmer, L.J., Penninx, B.W., Peters, A., Pramstaller, P.P., Raitakari, O.T., Rankinen, T.,
Rao, D.C., Rice, T.K., Ridker, P.M., Ritchie, M.D., Rudan, I., Salomaa, V., Samani, N.J., Saramies, J.,
Sarzynski, M.A., Schwarz, P.E., Shuldiner, A.R., Staessen, J.A., Steinthorsdottir, V., Stolk, R.P., Strauch,
K., Tönjes, A., Tremblay, A., Tremoli, E., Vohl, M.C., Völker, U., Vollenweider, P., Wilson, J.F., Witteman,
J.C., Adair, L.S., Bochud, M., Boehm, B.O., Bornstein, S.R., Bouchard, C., Cauchi, S., Caulfield, M.J.,
page 67 of 213
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° corresponding authors
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Chambers, J.C., Chasman, D.I., Cooper, R.S., Dedoussis, G., Ferrucci, L., Froguel, P., Grabe, H.J.,
Hamsten, A., Hui, J., Hveem, K., Jockel, K.H., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Marz, W., Munroe,
P.B., Njølstad, I., Oostra, B.A., Palmer, C.N., Pedersen, N.L., Perola, M., Perusse, L., Peters, U., Power, C.,
Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo, T.E., Saleheen, D., Sinisalo, J., Slagboom, P.E.,
Snieder, H., Spector, T.D., Thorsteinsdottir, U., Stumvoll, M., Tuomilehto, J., Uitterlinden, A.G., Uusitupa, M.,
van der Harst, P., Veronesi, G., Walker, M., Wareham, N.J., Watkins, H., Wichmann, H.-E., Abecasis, G.R.,
Assimes, T.L., Berndt, S.I., Boehnke, M., Borecki, I.B., Deloukas, P., Franke, L., Frayling, T.M., Groop, L.C.,
Hunter, D.J., Kaplan, R.C., O'Connell, J.R., Qi, L., Schlessinger, D., Strachan, D.P., Stefansson, K., van
Duijn, C.M., Willer, C.J., Visscher, P.M., Yang, J., Hirschhorn, J.N., Zillikens, M.C., McCarthy, M.I., Speliotes,
E.K., North, K.E., Fox, C.S., Barroso, I., Franks, P.W., Ingelsson, E., Heid, I.M., Loos, R.J., Cupples, L.A.,
Morris, A.P., Lindgren, C.M.°, Mohlke, K.L.°: New genetic loci link adipose and insulin biology to body fat
distribution. Nature 518, 187-196 (2015)
Sigurdsson, M.I.°, Muehlschlegel, J.D., Fox, A.A., Heydarpour, M., Lichtner, P., Meitinger, T., Collard, C.D.,
Shernan, S.K., Body, S.C.: Genetic variants associated with atrial fibrillation and PR interval following cardiac
surgery. J. Cardiothorac. Vasc. Anesth. 29, 605-610 (2015)
Sim, N., Gottschalk, S., Pal, R., Delbianco, M., Degtyaruk, O., Razansky, D., Westmeyer, G.G.,
Ntziachristos, V., Parker, D., Mishra, A.°: Wavelength-dependent optoacoustic imaging probes for NMDA
receptor visualisation. Chem. Commun. 51, 15149-15152 (2015)
Simon-Sanchez, J., Heutink, P., Gasser, T.°, International Parkinson's Disease Genomics Consortium
(IPDGC) (Illig, T., Lichtner, P.): Variation in PARK10 is not associated with risk and age at onset
of Parkinson's disease in large clinical cohorts. Neurobiol. Aging 36, 2907.e13-2907.e17 (2015)
Simpkin, A.J.°, Hemani, G., Suderman, M.J., Gaunt, T.R., Lyttleton, O., McArdle, W.L., Ring, S.M., Sharp,
G.C., Tilling, K., Horvath, S., Kunze, S., Peters, A., Waldenberger, M., Ward-Caviness, C.K., Nohr, E.A.,
Sørensen, T.I., Relton, C.L., Smith, G.D.: Prenatal and early life influences on epigenetic age in children: A
study of mother-offspring pairs from two cohort studies. Hum. Mol. Genet. 25, 191-201 (2016) [published
online 2015]
Singmann, P.°, Shem-Tov, D., Wahl, S., Grallert, H., Fiorito, G., Shin, S.Y., Schramm, K., Wolf, P.,
Kunze, S., Baran, Y., Guarrera, S., Vineis, P., Krogh, V., Panico, S., Tumino, R., Kretschmer, A., Gieger,
C., Peters, A., Prokisch, H., Relton, C.L., Matullo, G., Illig, T., Waldenberger, M., Halperin, E.:
Characterization of whole-genome autosomal differences of DNA methylation between men and women.
Epigenetics Chromatin 8:43 (2015)
Sinreih, M., Zukunft, S., Sosič, I., Cesar, J., Gobec, S., Adamski, J., Lanisnik Rizner, T.: Combined liquid
chromatography - tandem mass spectrometry analysis of progesterone metabolites. PLoS ONE
10:e0117984 (2015)
Sirko, S., Irmler, M., Gascón, S., Bek, S., Schneider, S., Dimou, L., Obermann, J., de Souza Paiva, D.,
Poirier, F., Beckers, J., Hauck, S.M., Barde, Y.A., Götz, M.°: Astrocyte reactivity after brain injury - the role
of galectins 1 and 3. Glia 63, 2340-2361 (2015)
page 68 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Song, H., Lee, B., Pyun, D., Guimera, J., Son, Y., Yoon, J., Baek, K., Wurst, W., Jeong, Y.°: Ascl1 and Helt
act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. Dev. Biol. 398,
280-291 (2015)
Sperl, W.J.K.°, Fleuren, L., Freisinger, P., Haack, T.B., Ribes, A.A., Feichtinger, R.G., Rodenburg, R.J.T.,
Zimmermann, F.A., Koch, J., Rivera, I.A., Prokisch, H., Smeitink, J.A.M., Mayr, J.A.: The spectrum of
pyruvate oxidation defects in the diagnosis of mitochondrial disorders. J. Inherit. Metab. Dis. 38, 391-403
(2015)
#
#
Spjuth, O. , Krestyaninova, M. °, Hastings, J., Shen, H.Y., Heikkinen, J., Waldenberger, M., Langhammer,
A., Ladenvall, C., Esko, T., Persson, M., Heggland, J., Dietrich, J., Ose, S., Gieger, C., Ried, J.S., Peters,
A., Fortier, I., de Geus, E.J., Klovins, J., Zaharenko, L., Willemsen, G., Hottenga, J.J., Litton, J.E., Karvanen,
J., Boomsma, D.I., Groop, L., Rung, J., Palmgren, J., Pedersen, N.L., McCarthy, M.I., van Duijn, C.M.,
Hveem, K., Metspalu, A., Ripatti, S., Prokopenko, I., Harris, J.R.: Harmonising and linking biomedical and
clinical data across disparate data archives to enable integrative cross-biobank research. Eur. J. Hum.
Genet. 24, 521-528 (2016) [published online 2015]
Srivastava, S., Engels, H., Schanze, I., Cremer, K., Wieland, T., Menzel, M., Schubach, M., Biskup, S.,
Kreiß, M., Endele, S., Strom, T.M., Wieczorek, D., Zenker, M., Gupta, S., Cohen, J., Zink, A.M., Naidu, S.°:
Loss-of-function variants in HIVEP2 are a cause of intellectual disability. Eur. J. Hum. Genet. 24, 556-561
(2016) [published online 2015]
Stangl, S., Kollerits, B., Lamina, C., Meisinger, C., Huth, C., Stöckl, A., Dähnhardt, D., Böger, C.A., Krämer,
B.K., Peters, A., Kronenberg, F.: Association between apolipoprotein A-IV concentrations and chronic kidney
disease in two large population-based cohorts: Results from the KORA studies. J. Intern. Med. 278, 410-423
(2015)
Staufner, C.#, Haack, T.B.#, Köpke, M., Straub, B.K., Kolker, S., Thiel, C., Freisinger, P., Baric, I.,
McKiernan, P.J., Dikow, N., Harting, I., Beisse, F., Burgard, P., Kotzaeridou, U., Lenz, D.R., Kühr, J.,
Himbert, U., Taylor, R.W., Distelmaier, F., Vockley, J., Ghaloul-Gonzalez, L., Ozolek, J.A., Zschocke, J.,
Kuster, A., Dick, A., Das, A.M., Wieland, T., Terrile, C., Strom, T.M., Meitinger, T., Prokisch, H.#,
Hoffmann, G.F.#°: Recurrent acute liver failure due to NBAS deficiency: Phenotypic spectrum, disease
mechanisms, and therapeutic concepts. J. Inherit. Metab. Dis. 39, 3-16 (2016) [published online 2015]
Steichen-Gersdorf, E.°, Lorenz-Depiereux, B., Strom, T.M., Shaw, N.J.: Early onset hearing loss in
autosomal recessive hypophosphatemic rickets caused by loss of function mutation in ENPP1. J. Pediatr.
Endocrinol. Metab. 28, 967-970 (2015)
Stiel, A.C., Dean-Ben, X.L., Jiang, Y., Ntziachristos, V., Razansky, D., Westmeyer, G.G.°: High-contrast
imaging of reversibly switchable fluorescent proteins via temporally unmixed multispectral optoacoustic
tomography. Opt. Lett. 40, 367-370 (2015)
page 69 of 213
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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Stitziel, N.O., Won, H., Morrison, A.C., Peloso, G.M., Do, R., Lange, L.A., Fontanillas, P., Gupta, N., Duga,
S., Goel, A.K., Farrall, M.J., Saleheen, D., Ferrario, P., König, I.R., Asselta, R., Merlini, P.A., Marziliano, N.,
Notarangelo, M.F., Schick, U.M., Auer, P.L., Assimes, T.L., Reilly, M.P., Wilensky, R.L., Rader, D.J., Kees
Hovingh, G., Meitinger, T., Kessler, T., Kastrati, A., Laugwitz, K.L., Siscovick, D.S., Rotter, J.I., Hazen, S.L.,
Tracy, R.P., Cresci, S.G., Spertus, J.A., Jackson, R.D., Schwartz, S.M., Natarajan, P., Crosby, J.R., Muzny,
D.M., Ballantyne, C.M., Rich, S.S., O'Donnell, C.J., Abecasis, G.R., Sunyaev, S.R., Nickerson, D.A., Buring,
J.E., Ridker, P.M., Chasman, D.I., Austin, E., Ye, Z., Kullo, I.J., Weeke, P.E., Shaffer, C.M., Bastarache,
L.A., Denny, J.C., Roden, D.M., Palmer, C.N.A., Deloukas, P., Lin, D., Tang, Z., Erdmann, J., Schunkert, H.,
Danesh, J., Marrugat, J., Elosua, R., Ardissino, D., McPherson, R.M., Watkins, H., Reiner, A.P., Wilson, J.G.,
Altshuler, D., Gibbs, R.A.L., Lander, E.S., Boerwinkle, E.E., Gabriel, S.B., Kathiresan, S.°: Inactivating
mutations in NPC1L1 and protection from coronary heart disease. N. Engl. J. Med. 371, 2072-2082 (2014)
Stuart, P.E.#, Nair, R.P.#, Tsoi, L.C.#, Tejasvi, T., Das, S., Kang, H.M., Ellinghaus, E., Chandran, V.,
Callis-Duffin, K., Ike, R.W., Li, Y., Wen, X., Enerbäck, C., Gudjonsson, J.E., Kõks, S., Kingo, K., Esko, T.,
Mrowietz, U., Reis, A., Wichmann, H.-E., Gieger, C., Hoffmann, P., Nöthen, M.M., Winkelmann, J., Kunz,
M., Moreta, E.G., Mease, P.J., Ritchlin, C.T., Bowcock, A.M., Krueger, G.G., Lim, H.W., Weidinger, S.,
Weichenthal, M., Voorhees, J.J., Rahman, P., Gregersen, P.K., Franke, A., Gladman, D.D., Abecasis, G.R.,
Elder, J.T.°: Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals
differences in their genetic architecture. Am. J. Hum. Genet. 97, 816-836 (2015)
Su, C.°, Hampel, R., Franck, U., Wiedensohler, A., Cyrys, J., Pan, X., Wichmann, H.-E., Peters, A.,
Schneider, A.E., Breitner, S.: Assessing responses of cardiovascular mortality to particulate matter air
pollution for pre-, during- and post-2008 Olympics periods. Environ. Res. 142, 112-122 (2015)
Su, C.°, Breitner, S., Schneider, A.E., Liu, L., Franck, U., Peters, A., Pan, X.: Short-term effects of fine
particulate air pollution on cardiovascular hospital emergency room visits: A time-series study in Beijing,
China. Int. Arch. Occup. Environ. Health 89, 641-657 (2016) [published online 2015]
Surakka, I., Horikoshi, M., Mägi, R., Sarin, A.P., Mahajan, A., Lagou, V., Marullo, L., Ferreira, T., Miraglio, B.,
Timonen, S., Kettunen, J., Pirinen, M., Karjalainen, J., Thorleifsson, G., Hägg, S., Hottenga, J.J., Isaacs, A.,
Ladenvall, C., Beekman, M., Esko, T., Ried, J.S., Nelson, C.P., Willenborg, C., Gustafsson, S., Westra, H.J.,
Blades, M., de Craen, A.J., de Geus, E.J., Deelen, J., Grallert, H., Hamsten, A., Havulinna, A.S.,
Hengstenberg, C., Houwing-Duistermaat, J.J., Hyppönen, E., Karssen, L.C., Lehtimäki, T., Lyssenko, V.,
Magnusson, P.K., Mihailov, E., Müller-Nurasyid, M., Mpindi, J.P., Pedersen, N.L., Penninx, B.W., Perola,
M., Pers, T.H., Peters, A., Rung, J., Smit, J.H., Steinthorsdottir, V., Tobin, M.D., Tsernikova, N., van
Leeuwen, E.M., Viikari, J.S., Willems, S.M., Willemsen, G., Schunkert, H., Erdmann, J., Samani, N.J.,
Kaprio, J., Lind, L., Gieger, C., Metspalu, A., Slagboom, P.E., Groop, L., van Duijn, C.M., Eriksson, J.G.,
Jula, A., Salomaa, V., Boomsma, D.I., Power, C., Raitakari, O.T., Ingelsson, E., Jarvelin, M.R.,
Thorsteinsdottir, U., Franke, L., Ikonen, E., Kallioniemi, O., Pietiäinen, V., Lindgren, C.M., Stefansson, K.,
Palotie, A., McCarthy, M.I., Morris, A.P., Prokopenko, I., Ripatti, S.°: The impact of low-frequency and rare
variants on lipid levels. Nat. Genet. 47, 589-597 (2015)
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Systemic Analysis of Genetic and Environmental Factors that Impact Health
#
#
Swerdlow, D.I. , Preiss, D. , Kuchenbaecker, K.B., Holmes, M.V., Engmann, J.E.L., Shah, T., Sofat, R.,
Stender, S., Johnson, P.C.D., Scott, R.A., Leusink, M., Verweij, N., Sharp, S.J., Guo, Y., Giambartolomei, C.,
Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J., Howard, P., Cooper, J.A., Drenos, F., Li, Y.R., Lowe,
G., Gallacher, J., Stewart, M.C.W., Tzoulaki, I., Buxbaum, S.G., Daphne, L.v.d.A., Forouhi, N.G.,
Onland-Moret, N.C., van der Schouw, Y.T., Schnabel, R.B., Hubácek, J.A., Kubínová, R., Baceviciene, M.,
Tamosiunas, A., Pajak, A., Topor-Madry, R., Stepaniak, U., Malyutina, S.A., Baldassarre, D., Sennblad, B.,
Tremoli, E., de Faire, U., Veglia, F., Ford, I., Jukema, J.W., Westendorp, R.G.J., de Borst, G.J., De Jong,
P.A., Algra, A., Spiering, W., Maitland-van der Zee, A.H., Klungel, O.H., de Boer, A., Doevendans, P.A.,
Eaton, C.B., Robinson, J.G., Duggan, D., Kjekshus, J., Downs, J.R., Gotto, A.M., Keech, A.C., Marchioli, R.,
Tognoni, G., Sever, P.S., Poulter, N.R., Waters, D.D., Pedersen, T.R., Amarenco, P., Nakamura, H.,
McMurray, J.J.V., Lewsey, J.D., Chasman, D.I., Ridker, P.M., Maggioni, A.P., Tavazzi, L., Ray, K.K.,
Seshasai, S.R.K., Manson, J.E., Price, J.F., Whincup, P.H., Morris, R.W., Lawlor, D.A., Smith, G.D.,
Ben-Shlomo, Y., Schreiner, P.J., Fornage, M., Siscovick, D.S., Cushman, M., Kumari, M., Wareham, N.J.,
Verschuren, W.M.M., Redline, S., Patel, S.R., Whittaker, J.C., Hamsten, A., Delaney, J.A., Dale, C.E.,
Gaunt, T.R., Wong, A., Kuh, D., Hardy, R., Kathiresan, S., Castillo, B.A., van der Harst, P., Brunner, E.J.,
Tybjaerg-Hansen, A., Marmot, M.G., Krauss, R.M., Tsai, M., Coresh, J., Hoogeveen, R.C., Psaty, B.M.,
Lange, L.A., Hakonarson, H., Dudbridge, F., Humphries, S.E., Talmud, P.J., Kivimaeki, M., Timpson, N.J.,
Langenberg, C., Asselbergs, F.W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J.G., Reiner, A.P., Keating,
B.J., Hingorani, A.D.°, Sattar, N.°, DIAGRAM Consortium (Grallert, H., Gieger, C., Klopp, N., Illig, T.,
Müller-Nurasyid, M., Peters, A.), MAGIC Consortium (Meisinger, C., Thorand, B., Wichmann, H.-E.),
InterAct Consortium: HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence
from genetic analysis and randomised trials. Lancet 385, 351-361 (2015)
Szentkirályi, A., Völzke, H., Hoffmann, W., Winkelmann, J., Berger, K.°: Lack of association between
genetic risk loci for restless legs syndrome and multimorbidity. Sleep 39, 111–115 (2015)
Taeger, D., Pesch, B., Kendzia, B., Behrens, T., Jockel, K.H., Dahmann, D., Siemiatycki, J., Kromhout, H.,
Vermeulen, R., Peters, S., Olsson, A., Brüske, I., Wichmann, H.-E., Stücker, I., Guida, F., Tardón, A.,
Merletti, F., Mirabelli, D., Richiardi, L., Pohlabeln, H., Ahrens, W., Landi, M.T., Caporaso, N., Pesatori, A.C.,
Mukeriya, A., Szeszenia-Dabrowska, N., Lissowska, J., Gustavsson, P., Field, J., Marcus, M.W., Fabianova,
E., 't Mannetje, A., Pearce, N., Rudnai, P., Bencko, V., Janout, V., Dumitru, R.S., Foretova, L., Forastiere, F.,
McLaughlin, J., Demers, P.D., Bueno-de-Mesquita, B., Schüz, J., Straif, K., Brüning, T.°: Lung cancer among
coal miners, ore miners and quarrymen: Smoking-adjusted risk estimates from the synergy pooled analysis
of case-control studies. Scand. J. Work Environ. Health 41, 467-477 (2015)
Tapper, W.#, Jones, A.V.#, Kralovics, R., Harutyunyan, A.S., Zoi, K., Leung, W., Godfrey, A.L., Guglielmelli,
P., Callaway, A., Ward, D., Aranaz, P., White, H.E., Waghorn, K., Lin, F., Chase, A.J., Baxter, E., Maclean,
C., Nangalia, J., Chen, E., Evans, P., Short, M., Jack, A., Wallis, L., Oscier, D., Duncombe, A.S., Schuh, A.,
Mead, A.J., Griffiths, M., Ewing, J., Gale, R.E., Schnittger, S., Haferlach, T., Stegelmann, F., Döhner, K.,
Grallert, H., Strauch, K., Tanaka, T., Bandinelli, S., Giannopoulos, A., Pieri, L., Mannarelli, C., Gisslinger,
H., Barosi, G., Cazzola, M., Reiter, A., Harrison, C.N., Campbell, P.J., Green, A.R., Vannucchi, A.M., Cross,
N.C.P.°: Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative
neoplasms. Nat. Commun. 6:6691 (2015)
page 71 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Teumer, A.°, Schurmann, C., Schillert, A., Schramm, K., Ziegler, A., Prokisch, H.: Analyzing illumina gene
expression microarray data obtained from human whole blood cell and blood monocyte samples. Methods
Mol. Biol. 1368, 85-97 (2016)
Teumer, A., Tin, A., Sorice, R., Gorski, M., Yeo, N.C., Chu, A.Y., Li, M., Li, Y., Mijatovic, V., Ko, Y.A., Taliun,
D., Luciani, A., Chen, M.H., Yang, Q., Foster, M.C., Olden, M., Hiraki, L.T., Tayo, B.O., Fuchsberger, C.,
Dieffenbach, A.K., Shuldiner, A.R., Smith, A.V., Zappa, A.M., Lupo, A., Kollerits, B., Ponte, B., Stengel, B.,
Krämer, B.K., Paulweber, B., Mitchell, B.D., Hayward, C., Helmer, C., Meisinger, C., Gieger, C., Shaffer,
C.M., Müller, C., Langenberg, C., Ackermann, D., Siscovick, D., Boerwinkle, E.E., Kronenberg, F., Ehret,
G.B., Homuth, G., Waeber, G., Navis, G., Gambaro, G., Malerba, G., Eiriksdottir, G., Li, G., Wichmann,
H.-E., Grallert, H., Wallaschofski, H., Völzke, H., Brenner, H., Kramer, H., Leach, I.M., Rudan, I., Hillege,
J.L., Beckmann, J.S., Lambert, J.C., Luan, J., Zhao, J.H., Chalmers, J., Coresh, J., Denny, J.C., Butterbach,
K., Launer, L.J., Ferrucci, L., Kedenko, L., Haun, M., Metzger, M., Woodward, M., Hoffman, M.J., Nauck, M.,
Waldenberger, M., Pruijm, M., Bochud, M., Rheinberger, M., Verweij, N., Wareham, N.J., Endlich, N.,
Soranzo, N., Polasek, O., van der Harst, P., Pramstaller, P.P., Vollenweider, P., Wild, P.S., Gansevoort,
R.T., Rettig, R., Biffar, R., Carroll, R.J., Katz, R., Loos, R.J., Hwang, S.J., Coassin, S., Bergmann, S., Rosas,
S.E., Stracke, S., Harris, T.B., Corre, T., Zeller, T., Illig, T., Aspelund, T., Tanaka, T., Lendeckel, U., Völker,
U., Gudnason, V., Chouraki, V., Koenig, W., Kutalik, Z., O'Connell, J.R., Parsa, A., Heid, I.M., Paterson,
A.D., de Boer, I.H., Devuyst, O., Lazar, J., Endlich, K., Susztak, K., Tremblay, J., Hamet, P., Jacob, H.J.,
Böger, C.A., Fox, C.S., Pattaro, C., Köttgen, A.: Genome-wide association studies identify genetic loci
associated with albuminuria in diabetes. Diabetes 65, 803-817 (2016) [published online 2015]
Thaler-Kall, K.°, Peters, A., Thorand, B., Grill, E., Autenrieth, C.S., Horsch, A.D., Meisinger, C.:
Description of spatio-temporal gait parameters in elderly people and their association with history of falls:
Results of the population-based cross-sectional KORA-Age study. BMC Geriatr. 15:32 (2015)
Theodorou, M.#, Rauser, B.#, Zhang, J., Prakash, N., Wurst, W., Schick, J.°: Limitations of in vivo
reprogramming to dopaminergic neurons via a tricistronic strategy. Hum. Gene Ther. Methods 26, 107-122
(2015)
Thiele, I.°, Linseisen, J., Meisinger, C., Schwab, S., Huth, C., Peters, A., Perz, S., Meitinger, T.,
Kronenberg, F., Lamina, C., Thiery, J., Koenig, W., Rathmann, W., Kääb, S., Then, C., Seissler, J.,
Thorand, B.: Associations between calcium and vitamin D supplement use as well as their serum
concentrations and subclinical cardiovascular disease phenotypes. Atherosclerosis 241, 743-751 (2015)
Thrift, A.P.°, Gong, J., Peters, U., Chang-Claude, J., Rudolph, A., Slattery, M.L., Chan, A.T., Esko, T., Wood,
A.R., Yang, J., Vedantam, S., Gustafsson, S., Pers, T.H., GIANT Consortium (Albrecht, E., Gieger, C.,
Grallert, H., Heid, I.M., Illig, T., Müller-Nurasyid, M., Peters, A., Thorand, B., Wichmann, H.-E.), Baron,
J.A., Bézieau, S., Kuery, S., Ogino, S., Berndt, S.I., Casey, G., Haile, R.W., Du, M., Harrison, T.A.,
Thornquist, M., Duggan, D.J., Le Marchand, L., Lemire, M., Lindor, N.M., Seminara, D., Song, M.,
Thibodeau, S.N., Cotterchio, M., Win, A.K., Jenkins, M.A., Hopper, J.L., Ulrich, C.M., Potter, J.D., Newcomb,
P.A., Schoen, R.E., Hoffmeister, M., Brenner, H., White, E.S., Hsu, L.A., Campbell, P.T.: Mendelian
randomization study of height and risk of colorectal cancer. Int. J. Epidemiol. 44, 662-672 (2015)
page 72 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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#
#
Tischner, C. , Hofer, A. , Wulff, V., Stepek, J., Dumitru, I., Becker, L., Haack, T.B., Kremer, L.S., Datta,
A.N., Sperl, W., Floß, T., Wurst, W., Chrzanowska-Lightowlers, Z.M., Hrabě de Angelis, M., Klopstock, T.,
Prokisch, H., Wenz, T.°: MTO1 mediates tissue-specificity of OXPHOS defects via tRNA modification and
translation optimization, which can be bypassed by dietary intervention. Hum. Mol. Genet. 24, 2247-2266
(2015)
Tokarz, J., Möller, G., Hrabě de Angelis, M., Adamski, J.°: Steroids in teleost fishes: A functional point of
view. Steroids 103, 123-144 (2015)
#
#
#
Toncheva, A.A. , Potaczek, D.P. , Schedel, M. , Gersting, S.W., Michel, S., Krajnov, N., Gaertner, V.D.,
Klingbeil, J.M., Illig, T., Franke, A., Winkler, C., Hohlfeld, J.M., Vogelberg, C., von Berg, A., Bufe, A.,
Heinzmann, A., Laub, O., Rietschel, E., Simma, B., Genuneit, J., Muntau, A.C., Kabesch, M.°: Childhood
asthma is associated with mutations and gene expression differences of ORMDL genes which can interact.
Allergy 70, 1288-1299 (2015)
Tönjes, A.#, Scholz, M.#, Breitfeld, J., Marzi, C., Grallert, H., Gross, A., Ladenvall, C., Schleinitz, D., Krause,
K.P., Kirsten, H., Laurila, E., Kriebel, J., Thorand, B., Rathmann, W., Groop, L.C., Prokopenko, I., Isomaa,
B., Beutner, F., Kratzsch, J.K., Thiery, J.J., Faßhauer, M., Klöting, N., Gieger, C., Blüher, M., Stumvoll,
M.W.°, Kovacs, P.°: Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the
regulation of circulating serum chemerin. PLoS Genet. 10:e1004854 (2015)
Truong, D.J.J., Kühner, K., Kühn, R., Werfel, S., Engelhardt, S., Wurst, W.°, Ortiz, O.°: Development of an
intein-mediated split-Cas9 system for gene therapy. Nucleic Acids Res. 43, 6450-6458 (2015)
Tsai, M.Y.°, Hoek, G., Eeftens, M., de Hoogh, K., Beelen, R., Beregszaszi, T., Cesaroni, G., Cirach, M.,
Cyrys, J., de Nazelle, A., de Vocht, F., Ducret-Stich, R., Eriksen, K., Galassi, C., Grazuleviciene, R.,
Gražulevicius, T., Grivas, G., Gryparis, A., Heinrich, J., Hoffmann, B., Iakovides, M., Keuken, M., Krämer,
U., Künzli, N., Lanki, T., Madsen, C., Meliefste, K., Merritt, A.S., Mölter, A., Mosler, G., Nieuwenhuijsen, M.J.,
Pershagen, G., Phuleria, H., Quass, U., Ranzi, A., Schaffner, E., Sokhi, R.S., Stempfelet, M., Stephanou, E.,
Sugiri, D., Taimisto, P., Tewis, M., Udvardy, O., Wang, M., Brunekreef, B.: Spatial variation of PM elemental
composition between and within 20 European study areas - results of the ESCAPE project. Environ. Int. 84,
181-192 (2015)
Tsepilov, Y.A., Shin, S.Y., Soranzo, N., Spector, T.D., Prehn, C., Adamski, J., Kastenmüller, G.,
Wang-Sattler, R., Strauch, K., Gieger, C., Aulchenko, Y.S., Ried, J.S.°: Non-additive effects of genes in
human metabolomics. Genetics 200, 707-718 (2015)
Tsuprykov, O., Chaykovska, L., Kretschmer, D., Stasch, J.-P., Pfab, T., Krause-Relle, K., Reichetzeder. C.,
Kalk, P., Adamski, J., Hocher, B.°: Endothelin-1 overexpression improves renal function in eNOS knockout
mice. Cell. Physiol. Biochem. 37, 1474-1490 (2015)
page 73 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Turpeinen, H.°, Seppälä, I.J.T., Lyytikäinen, L.P., Raitoharju, E., Hutri-Kähönen, N., Levula, M., Oksala,
N.K.J., Waldenberger, M., Klopp, N., Illig, T., Mononen, N., Laaksonen, R., Raitakari, O.T., Kähönen, M.,
Lehtimäki, T., Pesu, M.: A genome-wide expression quantitative trait loci analysis of proprotein convertase
subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure.
Hum. Genet. 134, 627-636 (2015)
van den Berg, R., Mook-Kanamori, D.O., Donga, E., van Dijk, M., van Dijk, J.G., Lammers, G.J., van
Kralingen, K.W., Prehn, C., Adamski, J., Romijn, J.A., Willems van Dijk, K., Corssmit, E.P.M., Rensen, P.C.,
Biermasz, N.R.°: A single night of sleep curtailment increases plasma acylcarnitines: Novel insights in the
relationship between sleep and insulin resistance. Arch. Biochem. Biophys. 589, 145-151 (2015)
van Dillen, T.°, Dekkers, F., Bijwaard, H., Brüske, I., Wichmann, H.-E., Kreuzer, M., Grosche, B.: Modeling
lung carcinogenesis in radon-exposed miner cohorts: Accounting for missing information on smoking. Risk
Anal., DOI: 10.1111/risa.12472 (2015)
Venco, P.#, Bonora, M.#, Giorgi, C.#, Papaleo, E., Iuso, A., Prokisch, H., Pinton, P., Tiranti, V.°: Mutations of
C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause
mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+.
Front. Genet. 6:185 (2015)
Viniol, A.°, Jegan, N., Brugger, M., Leonhardt, C., Barth, J., Baum, E., Becker, A., Strauch, K.: Even worse:
Risk factors and protective factors for transition from chronic localized low back pain to chronic widespread
pain in general practice - A cohort study. Spine 40, E890-E899 (2015)
Virtanen, M.°, Jokela, M., Nyberg, S.T., Madsen, I.E., Lallukka, T., Ahola, K., Alfredsson, L., Batty, G.D.,
Bjorner, J.B., Borritz, M., Burr, H., Casini, A., Clays, E., de Bacquer, D., Dragano, N., Erbel, R., Ferrie, J.E.,
Fransson, E.I., Hamer, M., Heikkilä, K., Jockel, K.H., Kittel, F., Knutsson, A., Koskenvuo, M., Ladwig, K.-H.,
Lunau, T., Nielsen, M.L., Nordin, M., Oksanen, T., Pejtersen, J.H., Pentti, J., Rugulies, R., Salo, P., Schupp,
J., Siegrist, J., Singh-Manoux, A., Steptoe, A., Suominen, S.B., Theorell, T., Vahtera, J., Wagner, G.G.,
Westerholm, P.J., Westerlund, H., Kivimaki, M.: Long working hours and alcohol use: Systematic review and
meta-analysis of published studies and unpublished individual participant data. Br. Med. J. 350:g7772 (2015)
#
#
Vogl, A.M. , Brockmann, M.M. , Giusti, S.A., Maccarrone, G., Vercelli, C.A., Bauder, C.A., Richter, J.S.,
Roselli, F., Hafner, A.S., Dedic, N., Wotjak, C.T., Vogt Weisenhorn, D.M., Choquet, D., Turck, C.W., Stein,
V., Deussing, J.M., Refojo, D.°: Neddylation inhibition impairs spine development, destabilizes synapses and
deteriorates cognition. Nat. Neurosci. 18, 239-251 (2015)
Vogt, S., Zierer, A., Laxy, M., Koenig, W., Linkohr, B., Linseisen, J., Peters, A., Thorand, B.°:
Association of serum vitamin D with change in weight and total body fat in a German cohort of older adults.
Eur. J. Clin. Nutr. 70, 136-139 (2016) [published online 2015]
page 74 of 213
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#
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° corresponding authors
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Vogt, S.°, Mielck, A., Berger, U., Grill, E., Peters, A., Döring, A., Holle, R., Strobl, R., Zimmermann, A.-K.,
Linkohr, B., Wolf, K., Kneißl, K., Maier, W.: Neighborhood and healthy aging in a German city: Distances to
green space and senior service centers and their associations with physical constitution, disability, and
health-related quality of life. Eur. J. Ageing 12, 273-283 (2015)
Vogt, S.°, Decke, S.°, de Las Heras Gala, T.°, Linkohr, B.°, Koenig, W.°, Ladwig, K.-H.°, Peters, A.°,
Thorand, B.°: Prospective association of vitamin D with frailty status and all-cause mortality in older adults:
Results from the KORA-Age study. Prev. Med. 73, 40-46 (2015)
Volaklis, K.A.°, Halle, M., Koenig, W., Oberhoffer, R., Grill, E., Peters, A., Strasser, B., Heier, M., Emeny,
R.T., Schulz, H., Ladwig, K.-H., Meisinger, C., Thorand, B.: Association between muscular strength and
inflammatory markers among elderly persons with cardiac disease: Results from the KORA-Age study. Clin.
Res. Cardiol. 104, 982-989 (2015)
Volaklis, K.A.°, Halle, M.R., Meisinger, C.: Muscular strength as a strong predictor of mortality: A narrative
review. Eur. J. Intern. Med. 26, 303-310 (2015)
#
#
Volckmar, A.L. , Song, J.Y. , Jarick, I., Pütter, C., Göbel, M., Horn, L.C., Struve, C., Haas, K., Knoll, N.,
Grallert, H., Illig, T., Reinehr, T., Wang, H.J., Hebebrand, J., Hinney, A.°: Fine mapping of a GWAS-derived
obesity candidate region on chromosome 16p11.2. PLoS ONE 10:e0125660 (2015)
von Eisenhart Rothe, A.#, Hutt, F.#, Baumert, J.J., Breithardt, G., Goette, A., Kirchhof, P., Ladwig, K.-H.°:
Depressed mood amplifies heart-related symptoms in persistent and paroxysmal atrial fibrillation patients: A
longitudinal analysis-data from the German competence network on atrial fibrillation. Europace 17,
1354-1362 (2015)
von Eisenhart Rothe, A., Albarqouni, L., Gärtner, C., Walz, L., Smenes, K.R., Ladwig, K.-H.°: Sex specific
impact of prodromal chest pain on pre-hospital delay time during an acute myocardial infarction: Findings
from the multicenter MEDEA study with 619 STEMI patients. Int. J. Cardiol. 201, 581-586 (2015)
von Hundelshausen, P., Oexle, K., Bidzhekov, K., Schmitt, M.M.N., Hristov, M., Blanchet, X., Kaemmerer,
H., Mátyás, G., Meitinger, T., Weber, C.M.°: Recurrent spontaneous coronary dissections in a patient with a
de novo fibrillin-1 mutation without Marfan syndrome. Thromb. Haemost. 113, 668-670 (2015)
Voss, A.°, Schroeder, R., Heitmann, A., Peters, A., Perz, S.: Short-term heart rate variability-influence of
gender and age in healthy subjects. PLoS ONE 10:e0118308 (2015)
Wahl, S.#°, Vogt, S.#, Stückler, F., Krumsiek, J., Bartel, J., Kacprowski, T., Schramm, K., Carstensen, M.,
Rathmann, W., Roden, M., Jourdan, C., Kangas, A.J., Soininen, P., Ala-Korpela, M., Nöthlings, U., Boeing,
H., Theis, F.J., Meisinger, C., Waldenberger, M., Suhre, K., Homuth, G., Gieger, C., Kastenmüller, G.,
Illig, T., Linseisen, J., Peters, A., Prokisch, H., Herder, C., Thorand, B.°, Grallert, H.°: Multi-omic
signature of body weight change: Results from a population-based cohort study. BMC Med. 13:48 (2015)
page 75 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
#
#
Wain, L.V. , Shrine, N. , Miller, S., Jackson, V.E., Ntalla, I., Artigas, M.S., Billington, C.K., Kheirallah, A.K.,
Allen, R.P., Cook, J.P., Probert, K., Obeidat, M., Bossé, Y., Hao, K., Postma, D.S., Paré, P.D., Ramasamy,
A., Mägi, R., Mihailov, E., Reinmaa, E., Melén, E., O'Connell, J., Frangou, E., Delaneau, O., UK Brain
Expression Consortium (Lamina, C., Rawal, R., Wichmann, H.-E.), Freeman, C., Petkova, D., McCarthy,
M., Sayers, I., Deloukas, P., Hubbard, R., Pavord, I.D., Hansell, A.L., Thomson, N.C., Zeggini, E., Morris,
A.P., Marchini, J., Strachan, D.P., Tobin, M.D.°, Hall, I.P.: Novel insights into the genetics of smoking
behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): A genetic association
study in UK Biobank. Lancet Resp. Med. 3, 769-781 (2015)
Wang, L., Aasly, J.O., Annesi, G., Bardien, S., Bozi, M., Brice, A., Carr, J.J., Chung, S.J., Clarke, C.,
Crosiers, D., Deutschländer, A., Eckstein, G.N., Farrer, M.J., Goldwurm, S., Garraux, G., Hadjigeorgiou,
G.M., Hicks, A.A., Hattori, N., Klein, C., Jeon, B., Kim, Y.J., Lesage, S., Lin, J.J., Lynch, T., Lichtner, P.,
Lang, A.E., Mok, V., Jasinska-Myga, B., Mellick, G.D., Morrison, K.E., Opala, G., Pihlstrom, L., Pramstaller,
P.P., Park, S.S., Quattrone, A., Rogaeva, E., Ross, O.A., Stefanis, L., Stockton, J.D., Silburn, P.A., Theuns,
J., Tan, E.K., Tomiyama, H., Toft, M.F., van Broeckhoven, C., Uitti, R.J., Wirdefeldt, K., Wszolek, Z.,
Xiromerisiou, G., Yueh, K.C., Zhao, Y., Gasser, T., Maraganore, D.M., Kruger, R., Sharma, M.°: Large-scale
assessment of polyglutamine repeat expansions in Parkinson disease. Neurology 85, 1283-1292 (2015)
Wanner, M., Richard, A., Martin, B.W., Linseisen, J., Rohrmann, S.°: Associations between objective and
self-reported physical activity and vitamin D serum levels in the US population. Cancer Causes Control 26,
881-891 (2015)
Washkowitz, A.J., Schall, C., Zhang, K.L., Wurst, W., Floß, T., Mager, J., Papaioannou, V.E.°: Mga is
essential for the survival of pluripotent cells during peri-implantation development. Development 142, 31-40
(2015)
Weber, S., Salabei, J.K., Möller, G., Kremmer, E., Bhatnagar, A., Adamski, J.°, Barski, O.A.°: Aldo-Keto
Reductase 1B15 (AKR1B15): A mitochondrial human aldo-keto reductase with activity toward steroids and
3-keto-acyl-CoA conjugates. J. Biol. Chem. 290, 6531-6545 (2015)
Weinmaier, T.#, Hoser, J.D.S.#, Eck, S., Kaufhold, I., Shima, K., Strom, T.M., Rattei, T., Rupp, J.°: Genomic
factors related to tissue tropism in Chlamydia pneumoniae infection. BMC Genomics 16:268 (2015)
Wende, C.-Z., Zoubaa, S., Blak, A.A., Echevarria, D., Martinez, S., Guillemot, F., Wurst, W., Guimera, J.°:
Hairy/enhancer-of-split MEGANE and proneural MASH1 factors cooperate synergistically in midbrain
GABAergic neurogenesis. PLoS ONE 10:e0127681 (2015)
page 76 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
#
#
Westra, H.J. , Arends, D. , Esko, T., Peters, M.J., Schurmann, C., Schramm, K., Kettunen, J., Yaghootkar,
H., Fairfax, B.P., Andiappan, A.K., Li, Y., Fu, J., Karjalainen, J., Platteel, M., Visschedijk, M., Weersma, R.K.,
Kasela, S., Milani, L., Tserel, L., Peterson, P., Reinmaa, E., Hofman, A., Uitterlinden, A.G., Rivadeneira, F.,
Homuth, G., Petersmann, A., Lorbeer, R., Prokisch, H., Meitinger, T., Herder, C., Roden, M., Grallert, H.,
Ripatti, S., Perola, M., Wood, A.R., Melzer, D., Ferrucci, L., Singleton, A.B., Hernandez, D.G., Knight, J.C.,
Melchiotti, R., Lee, B., Poidinger, M., Zolezzi, F., Larbi, A., Wang, Y., van den Berg, L.H., Veldink, J.H.,
Rotzschke, O., Makino, S., Salomaa, V., Strauch, K., Völker, U., van Meurs, J.B., Metspalu, A., Wijmenga,
C., Jansen, R.C., Franke, L.°: Cell specific eQTL analysis without sorting cells. PLoS Genet. 11:e1005223
(2015)
White, I.R.°, Rapsomaniki, E., Emerging Risk Factors Collaboration (Meisinger, C.): Covariate-adjusted
measures of discrimination for survival data. Biom. J. 57, 592-613 (2015)
Williams, K.M., Bertelsen, G., Cumberland, P.M., Wolfram, C., Verhoeven, V.J., Anastasopoulos, E.,
Buitendijk, G.H., Cougnard-Grégoire, A., Creuzot-Garcher, C., Erke, M.G., Hogg, R., Höhn, R., Hysi, P.,
Khawaja, A.P., Korobelnik, J.F., Ried, J.S., Vingerling, J.R., Bron, A., Dartigues, J.F., Fletcher, A., Hofman,
A., Kuijpers, R.W., Luben, R.N., Oxele, K., Topouzis, F., von Hanno, T., Mirshahi, A., Foster, P.J., van Duijn,
C.M., Pfeiffer, N., Delcourt, C., Klaver, C.C., Rahi, J.S., Hammond, C.J.°: Increasing prevalence of myopia in
Europe and the impact of education. Ophthalmology 122, 1489-1497 (2015)
Williams, K.M., Verhoeven, V.J., Cumberland, P.M., Bertelsen, G., Wolfram, C., Buitendijk, G.H., Hofman, A.,
van Duijn, C.M., Vingerling, J.R., Kuijpers, R.W., Höhn, R., Mirshahi, A., Khawaja, A.P., Luben, R.N., Erke,
M.G., von Hanno, T., Mahroo, O., Hogg, R., Gieger, C., Cougnard-Grégoire, A., Anastasopoulos, E., Bron,
A., Dartigues, J.F., Korobelnik, J.F., Creuzot-Garcher, C., Topouzis, F., Delcourt, C., Rahi, J.S., Meitinger,
T., Fletcher, A., Foster, P.J., Pfeiffer, N., Klaver, C.C., Hammond, C.J.°: Prevalence of refractive error in
Europe: The European Eye Epidemiology (E3) consortium. Eur. J. Epidemiol. 30, 305-315 (2015)
#
#
Willmann, S. , Müller, N.S. , Engert, S., Sterr, M., Burtscher, I., Raducanu, A., Irmler, M., Beckers, J.,
Sass, S., Theis, F.J., Lickert, H.°: The global gene expression profile of the secondary transition during
pancreatic development. Mech. Dev. 139, 51-64 (2016) [published online 2015]
page 77 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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#
#
#
Winkler, T.W. , Justice, A.E. , Graff, M. , Barata, L. , Feitosa, M.F., Chu, S., Czajkowski, J., Esko, T., Fall, T.,
Kilpeläinen, T.O., Lu, Y., Mägi, R., Mihailov, E., Pers, T.H., Rüeger, S., Teumer, A., Ehret, G.B., Ferreira, T.,
Heard-Costa, N.L., Karjalainen, J., Lagou, V., Mahajan, A., Neinast, M.D., Prokopenko, I., Simino, J.,
Teslovich, T.M., Jansen, R., Westra, H.J., White, C.C., Absher, D., Ahluwalia, T.S., Ahmad, S., Albrecht, E.,
Alves, A.C., Bragg-Gresham, J.L., de Craen, A.J., Bis, J.C., Bonnefond, A., Boucher, G., Cadby, G., Cheng,
Y.C., Chiang, C.W., Delgado, G., Demirkan, A., Dueker, N., Eklund, N., Eiriksdottir, G., Eriksson, J.,
Feenstra, B., Fischer, K., Frau, F., Galesloot, T.E., Geller, F., Goel, A., Gorski, M., Grammer, T.B.,
Gustafsson, S., Haitjema, S., Hottenga, J.J., Huffman, J.E., Jackson, A.U., Jacobs, K.B., Johansson, A.,
Kaakinen, M., Kleber, M.E., Lahti, J., Mateo Leach, I., Lehne, B., Liu, Y., Lo, K.S., Lorentzon, M., Luan, J.,
Madden, P.A., Mangino, M., McKnight, B., Medina-Gomez, C., Monda, K.L., Montasser, M.E., Müller, G.,
Müller-Nurasyid, M., Nolte, I.M., Panoutsopoulou, K., Pascoe, L., Paternoster, L., Rayner, N.W., Renström,
F., Rizzi, F., Rose, L.M., Ryan, K.A., Salo, P., Sanna, S., Scharnagl, H., Shi, J., Smith, A.V., Southam, L.,
Stancáková, A., Steinthorsdottir, V., Strawbridge, R.J., Sung, Y.J., Tachmazidou, I., Tanaka, T., Thorleifsson,
G., Trompet, S., Pervjakova, N., Tyrer, J.P., Vandenput, L., van der Laan, S.W., van der Velde, N., van
Setten, J., van Vliet-Ostaptchouk, J.V., Verweij, N., Vlachopoulou, E., Waite, L.L., Wang, S.R., Wang, Z.,
Wild, S.H., Willenborg, C., Wilson, J.F., Wong, A., Yang, J., Yengo, L., Yerges-Armstrong, L.M., Yu, L.,
Zhang, W., Zhao, J.H., Andersson, E.A., Bakker, S.J., Baldassarre, D., Banasik, K., Barcella, M., Barlassina,
C., Bellis, C., Benaglio, P., Blangero, J., Blüher, M., Bonnet, F., Bonnycastle, L.L., Boyd, H.A., Bruinenberg,
M., Buchman, A.S., Campbell, H., Chen, Y.D., Chines, P.S., Claudi-Boehm, S., Cole, J., Collins, F.S., de
Geus, E.J., de Groot, L.C., Dimitriou, M., Duan, J., Enroth, S., Eury, E., Farmaki, A.E., Forouhi, N.G.,
Friedrich, N., Gejman, P.V., Gigante, B., Glorioso, N., Go, A.S., Gottesman, O., Gräßler, J., Grallert, H.,
Grarup, N., Gu, Y.M., Broer, L., Ham, A.C., Hansen, T., Harris, T.B., Hartman, C.A., Hassinen, M., Hastie,
N., Hattersley, A.T., Heath, A.C., Henders, A.K., Hernandez, D., Hillege, H., Holmen, O.L., Hovingh, K.G.,
Hui, J., Husemoen, L.L., Hutri-Kähönen, N., Hysi, P.G., Illig, T., de Jager, P.L., Jalilzadeh, S., Jørgensen, T.,
Jukema, J.W., Juonala, M., Kanoni, S., Karaleftheri, M., Khaw, K.T., Kinnunen, L., Kittner, S.J., Koenig, W.,
Kolcic, I., Kovacs, P., Krarup, N.T., Kratzer, W., Krüger, J., Kuh, D., Kumari, M., Kyriakou, T., Langenberg,
C., Lannfelt, L., Lanzani, C., Lotay, V., Launer, L.J., Leander, K., Lindstrom, J., Linneberg, A., Liu, Y.P.,
Lobbens, S., Luben, R., Lyssenko, V., Männisto, S., Magnusson, P.K., McArdle, W.L., Menni, C., Merger, S.,
Milani, L., Montgomery, G.W., Morris, A.P., Narisu, N., Nelis, M., Ong, K.K., Palotie, A., Perusse, L., Pichler,
I., Pilia, M.G., Pouta, A., Rheinberger, M., Ribel-Madsen, R., Richards, M., Rice, K.M., Rice, T.K., Rivolta, C.,
Salomaa, V., Sanders, A.R., Sarzynski, M.A., Scholtens, S., Scott, R.A., Scott, W.R., Sebert, S., Sengupta,
S., Sennblad, B., Seufferlein, T., Silveira, A., Slagboom, P.E., Smit, J.H., Sparsø, T.H., Stirrups, K., Stolk,
R.P., Stringham, H.M., Swertz, M.A., Swift, A.J., Syvanen, A.C., Tan, S.T., Thorand, B., Tönjes, A.,
Tremblay, A., Tsafantakis, E., van der Most, P.J., Völker, U., Vohl, M.C., Vonk, J.M., Waldenberger, M.,
Walker, R.W., Wennauer, R., Widen, E., Willemsen, G., Wilsgaard, T., Wright, A.F., Zillikens, M.C., van Dijk,
S.C., van Schoor, N.M., Asselbergs, F.W., de Bakker, P.I., Beckmann, J.S., Beilby, J., Bennett, D.A.,
Bergman, R.N., Bergmann, S., Böger, C.A., Boehm, B.O., Boerwinkle, E., Boomsma, D.I., Bornstein, S.R.,
Bottinger, E.P., Bouchard, C., Chambers, J.C., Chanock, S.J., Chasman, D.I., Cucca, F., Cusi, D.,
Dedoussis, G., Erdmann, J., Eriksson, J.G., Evans, D.A., de Faire, U., Farrall, M., Ferrucci, L., Ford, I.,
Franke, L., Franks, P.W., Froguel, P., Gansevoort, R.T., Gieger, C., Grönberg, H., Gudnason, V.,
Gyllensten, U., Hall, P., Hamsten, A., van der Harst, P., Hayward, C., Heliövaara, M., Hengstenberg, C.,
Hicks, A.A., Hingorani, A., Hofman, A., Hu, F., Huikuri, H.V., Hveem, K., James, A.L., Jordan, J.M., Jula, A.,
page 78 of 213
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° corresponding authors
HMGU authors are given in bold letters
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Kähönen, M., Kajantie, E., Kathiresan, S., Kiemeney, L.A., Kivimaki, M., Knekt, P.B., Koistinen, H.A.,
Kooner, J.S., Koskinen, S., Kuusisto, J., Maerz, W., Martin, N.G., Laakso, M., Lakka, T.A., Lehtimäki, T.,
Lettre, G., Levinson, D.F., Lind, L., Lokki, M.L., Mäntyselkä, P., Melbye, M., Metspalu, A., Mitchell, B.D., Moll,
F.L., Murray, J.C., Musk, A.W., Nieminen, M.S., Njølstad, I., Ohlsson, C., Oldehinkel, A.J., Oostra, B.A.,
Palmer, L.J., Pankow, J.S., Pasterkamp, G., Pedersen, N.L., Pedersen, O., Penninx, B.W., Perola, M.,
Peters, A., Polasek, O., Pramstaller, P.P., Psaty, B.M., Qi, L., Quertermous, T., Raitakari, O.T., Rankinen,
T., Rauramaa, R., Ridker, P.M., Rioux, J.D., Rivadeneira, F., Rotter, J.I., Rudan, I., den Ruijter, H.M.,
Saltevo, J., Sattar, N., Schunkert, H., Schwarz, P.E., Shuldiner, A.R., Sinisalo, J., Snieder, H., Sørensen,
T.I., Spector, T.D., Staessen, J.A., Stefania, B., Thorsteinsdottir, U., Stumvoll, M., Tardif, J.C., Tremoli, E.,
Tuomilehto, J., Uitterlinden, A.G., Uusitupa, M., Verbeek, A.L., Vermeulen, S.H., Viikari, J.S., Vitart, V.,
Völzke, H., Vollenweider, P., Waeber, G., Walker, M., Wallaschofski, H., Wareham, N.J., Watkins, H.,
Zeggini, E., CHARGE Consortium (Gieger, C., Meisinger, C., Prokisch, H., Wichmann, H.-E.), DIAGRAM
Consortium (Klopp, N., Meyer, J.), GLGC Consortium, Global BPgen Consortium (Döring, A.), ICBP
Consortium (Meitinger, T.), MAGIC Consortium, Chakravarti, A., Clegg, D.J., Cupples, L.A., Gordon-Larsen,
P., Jaquish, C.E., Rao, D.C., Abecasis, G.R., Assimes, T.L., Barroso, I., Berndt, S.I., Boehnke, M., Deloukas,
P., Fox, C.S., Groop, L.C., Hunter, D.J., Ingelsson, E., Kaplan, R.C., McCarthy, M.I., Mohlke, K.L.,
O'Connell, J.R., Schlessinger, D., Strachan, D.P., Stefansson, K., van Duijn, C.M., Hirschhorn, J.N.,
Lindgren, C.M., Heid, I.M.°, North, K.E.°, Borecki, I.B.°, Kutalik, Z.°, Loos, R.J.°: The influence of age and
sex on genetic associations with adult body size and shape: A large-scale genome-wide interaction study.
PLoS Genet. 11:e1005378 (2015)
Wittenbecher, C., Mühlenbruch, K., Kröger, J., Jacobs, S., Kuxhaus, O., Floegel, A., Fritsche, A., Pischon,
T., Prehn, C., Adamski, J., Joost, H.-G., Boeing, H., Schulze, M.B.°: Amino acids, lipid metabolites, and
ferritin as potential mediators linking red meat consumption to type 2 diabetes. Am. J. Clin. Nutr. 101,
1241-1250 (2015)
Wolf, K.°, Schneider, A.E., Breitner, S., Meisinger, C., Heier, M., Cyrys, J., Kuch, B., von Scheidt, W.,
Peters, A., KORA Study Group (Gieger, C., Grallert, H., Heinrich, J., Holle, R., Leidl, R., Strauch, K.):
Associations between short-term exposure to particulate matter and ultrafine particles and myocardial
infarction in Augsburg, Germany. Int. J. Hyg. Environ. Health 218, 535-542 (2015)
Wolf, K., Stafoggia, M., Cesaroni, G., Andersen, Z.J., Beelen, R., Galassi, C., Hennig, F., Migliore, E.,
Penell, J., Ricceri, F., Sørensen, M., Turunen, A.W., Hampel, R., Hoffmann, B., Kälsch, H., Laatikainen, T.,
Pershagen, G., Raaschou-Nielsen, O., Sacerdote, C., Vineis, P., Badaloni, C., Cyrys, J., de Hoogh, K.,
Eriksen, K.T., Jedynska, A., Keuken, M., Kooter, I.M., Lanki, T., Ranzi, A., Sugiri, D., Tsai, M.Y., Wang, M.,
Hoek, G., Brunekreef, B., Peters, A., Forastiere, F.: Long-term exposure to particulate matter constituents
and the incidence of coronary events in 11 European cohorts. Epidemiology 26, 565-574 (2015)
Wolfram, G., Bechthold, A., Boeing, H., Ellinger, S., Hauner, H., Kroke, A., Leschik-Bonnet, E., Linseisen,
J., Lorkowski, S., Schulze, M., Stehle, P., Dinter, J.°: Evidence-based guideline of the German Nutrition
Society: Fat intake and prevention of selected nutrition-related diseases. Ann. Nutr. Metab. 67, 141-204
(2015)
page 79 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Wortmann, S.B.°, Zietkiewicz, S., Kousi, M., Szklarczyk, R., Haack, T.B., Gersting, S.W., Muntau, A.C.,
Rakovic, A., Renkema, G.H., Rodenburg, R.J., Strom, T.M., Meitinger, T., Rubio-Gozalbo, M.E., Chrusciel,
E., Distelmaier, F., Golzio, C., Jansen, J.H., van Karnebeek, C., Lillquist, Y., Lücke, T., Ounap, K., Zordania,
R., Yaplito-Lee, J., van Bokhoven, H., Spelbrink, J.N., Vaz, F.M., Pras-Raves, M., Ploski, R., Pronicka, E.,
Klein, C., Willemsen, M.A., de Brouwer, A.P., Prokisch, H., Katsanis, N., Wevers, R.A.: CLPB mutations
cause 3-methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia,
cataracts, movement disorder. Am. J. Hum. Genet. 96, 245-257 (2015)
Würtz, P.°, Havulinna, A.S., Soininen, P., Tynkkynen, T., Prieto-Merino, D., Tillin, T., Ghorbani, A., Artati, A.,
Wang, Q., Tiainen, M., Kangas, A.J., Kettunen, J., Kaikkonen, J., Mikkilä, V., Jula, A., Kähönen, M.,
Lehtimäki, T., Lawlor, D.A., Gaunt, T.R., Hughes, A.D., Sattar, N., Illig, T., Adamski, J., Wang, T.J., Perola,
M., Ripatti, S., Vasan, R.S., Raitakari, O.T., Gerszten, R.E., Casas, J.P., Chaturvedi, N., Ala-Korpela, M.,
Salomaa, V.: Metabolite profiling and cardiovascular event risk: A prospective study of three
population-based cohorts. Circulation 131, 774-785 (2015)
Xu, T., Brandmaier, S., Messias, A.C., Herder, C., Draisma, H.H., Demirkan, A., Yu, Z., Ried, J.S., Haller,
T., Heier, M., Campillos, M., Fobo, G., Stark, R.G., Holzapfel, C., Adam, J., Chi, S., Rotter, M., Panni, T.,
Quante, A.S., He, Y., Prehn, C., Römisch-Margl, W., Kastenmüller, G., Willemsen, G., Pool, R., Kasa, K.,
van Dijk, K.W., Hankemeier, T., Meisinger, C., Thorand, B., Ruepp, A., Hrabě de Angelis, M., Li, Y.,
Wichmann, H.-E., Stratmann, B., Strauch, K., Metspalu, A., Gieger, C., Suhre, K., Adamski, J., Illig, T.,
Rathmann, W., Roden, M., Peters, A., van Duijn, C.M., Boomsma, D.I., Meitinger, T., Wang-Sattler, R.°:
Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes. Diabetes
Care 38, 1858-1867 (2015)
Yousri, N.A., Kastenmüller, G., AlHaq, W.G., Holle, R., Kääb, S., Mohney, R.P., Gieger, C., Peters, A.,
Adamski, J., Suhre, K., Arayssi, T.°: Diagnostic and prognostic metabolites identified for joint symptoms in
the KORA population. J. Proteome Res. 15, 554-562 (2016) [published online 2015]
Zech, M., Boesch, S., Jochim, A., Graf, S., Lichtner, P., Peters, A., Gieger, C., Mueller, J., Poewe, W.,
Haslinger, B., Winkelmann, J.°: Large-scale TUBB4A mutational screening in isolated dystonia and
controls. Parkinsonism Relat. Disord. 21, 1278-1281 (2015)
Zech, M.#, Lam, D.D.#, Francescatto, L.#, Schormair, B., Salminen, A.V., Jochim, A., Wieland, T.,
Lichtner, P., Peters, A., Gieger, C., Lochmüller, H., Strom, T.M., Haslinger, B., Katsanis, N., Winkelmann,
J.°: Recessive mutations in the α3 (VI) collagen gene COL6A3 cause early-onset isolated dystonia. Am. J.
Hum. Genet. 96, 883-893 (2015)
Zech, M., Boesch, S., Sycha, T., Mueller, J., Poewe, W., Winkelmann, J.°: TOR1A, THAP1, and GNAL
mutational screening in Austrian patients with primary isolated dystonia. Mov. Disord. 30, 1853–1854 (2015)
page 80 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Systemic Analysis of Genetic and Environmental Factors that Impact Health
Zeller, T.°, Haase, T., Müller, C., Riess, H., Lau, D., Zeller, S., Krause, J., Baumert, J.J., Pless, O., Dupuis,
J., Wild, P.S., Eleftheriadis, M.S., Waldenberger, M., Zeilinger, S., Ziegler, A., Peters, A., Tiret, L., Proust,
C., Marzi, C., Münzel, T., Strauch, K., Prokisch, H., Lackner, K.J., Herder, C., Thorand, B., Benjamin, E.J.,
Blankenberg, S., Koenig, W., Schnabel, R.B.: Molecular characterization of the NLRC4 expression in relation
to interleukin-18 levels. Circ. Cardiovasc. Genet. 8, 717-726 (2015)
Zewinger, S., Drechsler, C., Kleber, M.E., Dressel, A., Riffel, J., Triem, S., Lehmann, M., Kopecky, C.,
Säemann, M.D., Lepper, P.M., Silbernagel, G., Scharnagl, H., Ritsch, A., Thorand, B., de Las Heras Gala,
T., Wagenpfeil, S., Koenig, W., Peters, A., Laufs, U., Wanner, C., Fliser, D., Speer, T., Marz, W.°: Serum
amyloid A: High-density lipoproteins interaction and cardiovascular risk. Eur. Heart J. 36, 3007-3016 (2015)
Zhang, J., Götz, S., Vogt Weisenhorn, D.M., Simeone, A., Wurst, W., Prakash, N.: A WNT1-regulated
+/developmental gene cascade prevents dopaminergic neurodegeneration in adult En1 mice. Neurobiol. Dis.
82, 32-45 (2015)
Ziegler, D., Voss, A., Rathmann, W., Strom, A., Perz, S., Roden, M., Peters, A., Meisinger, C., KORA Study
Group (Heinrich, J., Gieger, C., Grallert, H., Holle, R., Leidl, R., Strauch, K.): Increased prevalence of
cardiac autonomic dysfunction at different degrees of glucose intolerance in the general population: The
KORA S4 survey. Diabetologia 58, 1118-1128 (2015)
Zimmermann, E., Ängquist, L.H., Mirza, S.S., Zhao, J.H., Chasman, D.I., Fischer, K., Qi, Q., Smith, A.V.,
Thinggaard, M., Jarczok, M.N., Nalls, M.A., Trompet, S., Timpson, N.J., Schmidt, B., Jackson, A.U.,
Lyytikäinen, L.P., Verweij, N., Müller-Nurasyid, M., Vikström, M., Marques-Vidal, P., Wong, A., Meidtner, K.,
Middelberg, R.P., Strawbridge, R.J., Christiansen, L., Kyvik, K.O.H.M., Hamsten, A., Jääskeläinen, T.,
Tjönneland, A.M., Eriksson, J.G., Whitfield, J.B., Boeing, H., Hardy, R., Vollenweider, P., Leander, K.,
Peters, A., van der Harst, P., Kumari, M., Lehtimäki, T., Meirhaeghe, A., Tuomilehto, J.O.I., Jockel, K.H.,
Ben-Shlomo, Y., Sattar, N.A., Baumeister, S.E., Davey Smith, G., Casas, J.P., Houston, D.K., Marz, W.,
Christensen, K., Gudnason, V.G., Hu, F.B., Metspalu, A., Ridker, P.M., Wareham, N.J., Loos, R.J.F.,
Tiemeier, H.M., Sonestedt, E., Sørensen, T.I.A.°: Is the adiposity-associated FTO gene variant related to
all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults. Obes.
Rev. 16, 327-340 (2015)
Zimmermann, H.#°, Hagenfeld, D.#, Diercke, K., El-Sayed, N., Fricke, J., Greiser, K.H., Kühnisch, J.,
Linseisen, J., Meisinger, C., Pischon, N., Pischon, T., Samietz, S., Schmitter, M., Steinbrecher, A., Kim,
T.S., Becher, H.: Pocket depth and bleeding on probing and their associations with dental, lifestyle,
socioeconomic and blood variables: A cross-sectional, multicenter feasibility study of the German National
Cohort. BMC Oral Health 15:7 (2015)
Østergaard, S.D., Mukherjee, S., Sharp, S.J., Proitsi, P., Lotta, L.A., Day, F., Perry, J.R., Boehme, K.L.,
Walter, S., Kauwe, J.S., Gibbons, L.E., Alzheimer's Disease Neuroimaging Initiative, Genetic and
Environmental Risk for Alzheimer's Disease (GERAD1) Consortium (Klopp, N., Wichmann, H.-E.),
EPIC-Interact Consortium (Scott, R.A.°), Larson, E.B., Powell, J.F., Langenberg, C.: Associations between
potentially modifiable risk factors and Alzheimer disease: A mendelian randomization study. PLoS Med.
12:e1001841 (2015)
page 81 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Diabetes: Pathophysiology, Prevention and Therapy
Agardh, D.°, Lee, H.S., Kurppa, K., Simell, V., Aronsson, C.A., Jörneus, O., Hummel, M., Liu, E., Koletzko,
S., TEDDY Study Group (Ziegler, A.-G., Beyerlein, A., Hummel, S., Knopff, A., Peplow, C., Roth, R.,
Stock, J., Strauss, E., Warncke, K., Winkler, C.): Clinical features of celiac disease: A prospective birth
cohort. Pediatrics 135, 627-634 (2015)
Aronsson, C.A.°, Uusitalo, U., Vehik, K., Yang, J., Silvis, K., Hummel, S., Virtanen, S.M., Norris, J.M.,
TEDDY Study Group (Ziegler, A.-G., Beyerlein, A., Henneberger, L., Hummel, M., Knopff, A., Krause, S.,
Peplow, C., Pflüger, M., Roth, R., Schenkel, J., Stock, J., Strauss, E., Warncke, K., Winkler, C.): Age at
first introduction to complementary foods is associated with sociodemographic factors in children with
increased genetic risk of developing type 1 diabetes. Matern. Child Nutr. 11, 803-814 (2015)
Aronsson, C.A.°, Lee, H.S., Liu, E., Uusitalo, U., Hummel, S., Yang, J., Hummel, M., Rewers, M., She, J.X.,
Simell, O., Toppari, J., Ziegler, A.-G., Krischer, J., Virtanen, S.M., Norris, J.M., Agardh, D., TEDDY Study
Group (Beyerlein, A., Knopff, A., Peplow, C., Roth, R., Stock, J., Strauss, E., Warncke, K., Winkler, C.):
Age at gluten introduction and risk of celiac disease. Pediatrics 135, 239-245 (2015)
Barlow, J., Hirschberg Jensen, V., Jastroch, M., Affourtit, C.: Palmitate-induced impairment of
glucose-stimulated insulin secretion precedes mitochondrial dysfunction in mouse pancreatic islets.
Biochem. J., DOI: 10.1042/BJ20151080 (2015)
Bayindir, I., Babaeikelishomi, R., Kocanova, S., Sousa, I.S., Lerch, S., Hardt, O., Wild, S., Bosio, A.,
Bystricky, K., Herzig, S., Vegiopoulos, A.°: Transcriptional pathways in cPGI2-induced adipocyte progenitor
activation for browning. Front. Endocrin. 6:129 (2015)
Beranger, G.E., Djedaini, M., Battaglia, S., Roux, C.H., Scheideler, M., Heymann, D., Amri, E.Z.°, Pisani,
D.F.°: Oxytocin reverses osteoporosis in a sex-dependent manner. Front. Endocrin. 6:81 (2015)
Berrios, C., Jung, J.U., Primi, B., Wang, M., Pedamallu, C., Duke, F., Marcelus, C., Cheng, J., Garcea, R.L.,
Meyerson, M., DeCaprio, J.A.°, TEDDY Study Group (Ziegler, A.-G., Beyerlein, A., Henneberger, L.,
Hummel, M., Hummel, S., Knopff, A., Krause, S., Peplow, C., Pflüger, M., Roth, R., Schenkel, J., Stock,
J., Strauss, E., Warncke, K., Winkler, C.): Malawi polyomavirus is a prevalent human virus that interacts
with known tumor suppressors. J. Virol. 89, 857-862 (2015)
Berti, L., Irmler, M., Zdichavsky, M., Meile, T., Böhm, A., Stefan, N., Fritsche, A., Beckers, J.,
Königsrainer, A., Häring, H.-U., Hrabě de Angelis, M., Staiger, H.°: Fibroblast growth factor 21 is elevated
in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of
human abdominal subcutaneous adipocytes. Mol. Metab. 4, 519-527 (2015)
Beyerlein, A.°, Liu, X., Uusitalo, U.M., Harsunen, M.H., Norris, J.M., Foterek, K., Virtanen, S.M., Rewers,
M.J., She, J.X., Simell, O., Lernmark, A., Hagopian, W., Akolkar, B., Ziegler, A.-G., Krischer, J.P., Hummel,
S., TEDDY Study Group (Hummel, M., Knopff, A., Peplow, C., Roth, R., Stock, J., Strauss, E., Warncke,
K., Winkler, C.): Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: Results from the
TEDDY study. Am. J. Clin. Nutr. 102, 345-352 (2015)
page 82 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Diabetes: Pathophysiology, Prevention and Therapy
Bonifacio, E., Ziegler, A.-G., Klingensmith, G., Schober, E., Bingley, P.J., Rottenkolber, M., Theil, A.,
Eugster, A., Puff, R., Peplow, C., Buettner, F., Lange, K., Hasford, J., Achenbach, P.°: Effects of high-dose
oral insulin on immune responses in children at high risk for type 1 diabetes: The Pre-POINT randomized
clinical trial. JAMA 313, 1541-1549 (2015)
Bonifacio, E.°: Predicting type 1 diabetes using biomarkers. Diabetes Care 38, 989-996 (2015)
Bönisch, C., Irmler, M., Brachthäuser, L., Neff, F., Bamberger, M.T., Marschall, S., Hrabě de Angelis,
M., Beckers, J.: Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as
observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring. Mamm. Genome
27, 17-28 (2015)
Cheng, Y.S., Seibert, O., Klöting, N., Dietrich, A., Straßburger, K., Fernández-Veledo, S., Vendrell, J.J.,
Zorzano, A., Blüher, M., Herzig, S., Berriel Diaz, M.°, Teleman, A.A.°: PPP2R5C couples hepatic glucose
and lipid homeostasis. PLoS Genet. 11:e1005561 (2015)
Claussnitzer, M., Dankel, S.N., Kim, K.H., Quon, G., Meuleman, W., Haugen, C., Glunk, V., Sousa, I.S.,
Beaudry, J.L., Puviindran, V., Abdennur, N.A., Liu, J., Svensson, P.A., Hsu, Y.H., Drucker, D.J., Mellgren, G.,
Hui, C.C., Hauner, H., Kellis, M.°: FTO obesity variant circuitry and adipocyte browning in humans. N. Engl.
J. Med. 373, 895-907 (2015)
Clemmensen, C., Müller, T.D., Finan, B., Tschöp, M.H.°, DiMarchi, R.: Current and emerging treatment
options in diabetes care. Handb. Exp. Pharmacol. 233, 437-459 (2016) [published online 2015]
Clemmensen, C., Finan, B., Fischer, K., Tom, R.Z., Legutko, B., Sehrer, L., Heine, D., Grassl, N.,
Meyer, C.W., Henderson, B., Hofmann, S.M., Tschöp, M.H., van der Ploeg, L.H.T., Müller, T.D.°: Dual
melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese
mice. EMBO Mol. Med. 7, 288-298 (2015)
Dargel, C., Bassani-Sternberg, M., Hasreiter, J., Zani, F., Bockmann, J.H., Thiele, F., Bohne, F.,
Wisskirchen, K., Wilde, S., Sprinzl, M.F., Schendel, D.J., Krackhardt, A.M., Uckert, W., Wohlleber, D.,
Schiemann, M., Stemmer, K., Heikenwälder, M., Busch, D.H., Richter, G., Mann, M., Protzer, U.°: T cells
engineered to express a T-cell receptor specific for glypican-3 to recognize and kill hepatoma cells in vitro
and in mice. Gastroenterology 149, 1042-1052 (2015)
#
#
Deng, T. , Zhu, Z.I. , Zhang, S., Postnikov, Y., Huang, D., Horsch, M., Furusawa, T., Beckers, J., Rozman,
J., Klingenspor, M., Amarie, O.V., Graw, J., Rathkolb, B., Wolf, E., Adler, T., Busch, D.H.,
Gailus-Durner, V., Fuchs, H., Hrabě de Angelis, M., van der Velde, A., Tessarollo, L., Ovcherenko, I.,
Landsman, D., Bustin, M.°: Functional compensation among HMGN variants modulates the DNase I
hypersensitive sites at enhancers. Genome Res. 25, 1295-1308 (2015)
Diehl, K.L., Ivy, M.A., Rabidoux, S., Petry, S.M., Müller, G., Anslyn, E.V.°: Differential sensing for the regioand stereoselective identification and quantitation of glycerides. Proc. Natl. Acad. Sci. U.S.A. 112,
E3977-E3986 (2015)
page 83 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Diabetes: Pathophysiology, Prevention and Therapy
#
#
Dinter, J. , Mühlhaus, J. , Wienchol, C.L., Yi, C.-X., Nürnberg, D., Morin, S., Grüters, A., Köhrle, J.,
Schöneberg, T., Tschöp, M.H., Krude, H., Kleinau, G., Biebermann, H.°: Inverse agonistic action of
3-iodothyronamine at the human trace amine-associated receptor 5. PLoS ONE 10:e0117774 (2015)
Dopico, X.C., Evangelou, M., Ferreira, R.C., Guo, H., Pekalski, M.L., Smyth, D.J., Cooper, N., Burren, O.S.,
Fulford, A.J., Hennig, B.J., Prentice, A.M., Ziegler, A.-G., Bonifacio, E., Wallace, C., Todd, J.A.°:
Widespread seasonal gene expression reveals annual differences in human immunity and physiology. Nat.
Commun. 6:7000 (2015)
Eugster, A.°, Lindner, A., Catani, M., Heninger, A.K., Dahl, A., Klemroth, S., Kühn, D., Dietz, S., Bickle, M.,
Ziegler, A.-G., Bonifacio, E.: High diversity in the TCR repertoire of GAD65 autoantigen-specific human
+
CD4 T cells. J. Immunol. 194, 2531-2538 (2015)
Ferrari, U., Künzel, H.E.°, Tröndle, K., Rottenkolber, M., Kohn, D., Fugmann, M., Banning, F., Weise, M.,
Sacco, V., Hasbargen, U., Hutter, S., Parhofer, K.G., Kloiber, S., Ising, M., Seissler, J., Lechner, A.: Poor
sleep quality is associated with impaired glucose tolerance in women after gestational diabetes. J. Psychiatr.
Res. 65, 166-171 (2015)
Fiamoncini, J.°, Lima, T.M., Hirabara, S.M., Ecker, J., Gorjao, R., Romanatto, T., ELolimy, A., Worsch, S.,
Laumen, H., Bader, B., Daniel, H., Curi, R.: Medium-chain dicarboxylic acylcarnitines as markers of n-3
PUFA-induced peroxisomal oxidation of fatty acids. Mol. Nutr. Food Res. 59, 1573-1583 (2015)
Finan, B.°, Clemmensen, C., Müller, T.D.: Emerging opportunities for the treatment of metabolic diseases:
Glucagon-like peptide-1 based multi-agonists. Mol. Cell. Endocrinol. 418, 42-54 (2015)
Fuchs, Y.F., Jainta, G.W., Kühn, D., Wilhelm, C., Weigelt, M., Karasinsky, A., Upadhyaya, B., Ziegler, A.-G.,
Bonifacio, E.°: Vagaries of the ELISpot assay: Specific detection of antigen responsive cells requires
+
purified CD8 T cells and MHC class I expressing antigen presenting cell lines. Clin. Immunol. 157, 216-225
(2015)
Fugmann, M., Uhl, O., Hellmuth, C., Hetterich, H., Kammer, N.N., Ferrari, U., Parhofer, K.G., Koletzko, B.,
Seissler, J., Lechner, A.°: Differences in the serum nonesterified fatty acid profile of young women
associated with a recent history of gestational diabetes and overweight/obesity. PLoS ONE 10:e0128001
(2015)
Fugmann, M., Breier, M., Rottenkolber, M., Banning, F., Ferrari, U., Sacco, V., Grallert, H., Parhofer,
K.G., Seissler, J., Clavel, T., Lechner, A.°: The stool microbiota of insulin resistant women with recent
gestational diabetes, a high risk group for type 2 diabetes. Sci. Rep. 5:13212 (2015)
Gascón, S.#°, Murenu, E.#, Masserdotti, G., Ortega, F., Russo, G.L., Petrik, D., Deshpande, A., Heinrich,
C., Karow, M., Robertson, S.P., Schroeder, T., Beckers, J., Irmler, M., Berndt, C., Friedmann Angeli, J.P.,
Conrad, M., Berninger, B., Götz, M.°: Identification and successful negotiation of a metabolic checkpoint in
direct neuronal repogramming. Cell Stem Cell 18, 396-409 (2016) [published online 2015]
page 84 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Diabetes: Pathophysiology, Prevention and Therapy
Giannopoulou, E.Z., Winkler, C., Chmiel, R., Matzke, C., Scholz, M., Beyerlein, A., Achenbach, P.,
Bonifacio, E., Ziegler, A.-G.°: Islet autoantibody phenotypes and incidence in children at increased risk for
type 1 diabetes. Diabetologia 58, 2317-2323 (2015)
Grabner, G.F., Eichmann, T.O., Wagner, B., Gao, Y., Farzi, A., Taschler, U., Radner, F.P., Schweiger, M.,
Lass, A., Holzer, P., Zinser, E., Tschöp, M.H., Yi, C.-X., Zimmermann, R.: Deletion of monoglyceride lpase
in astrocytes attenuates lipopolysaccharide-induced neuroinflammation. J. Biol. Chem. 291, 913-923 (2016)
[published online 2015]
Gutierrez, D.A., Muralidhar, S., Feyerabend, T.B., Herzig, S., Rodewald, H.R.°: Hematopoietic Kit deficiency,
rather than lack of mast cells, protects mice from obesity and insulin resistance. Cell Metab. 21, 678-691
(2015)
Hadley, D.°, Hagopian, W., Liu, E., She, J.X., Simell, O., Akolkar, B., Ziegler, A.-G., Rewers, M., Krischer,
J.P., Chen, W.M., Onengut-Gumuscu, S., Bugawan, T.L., Rich, S.S., Erlich, H., Agardh, D., TEDDY Study
Group (Beyerlein, A., Hummel, M., Hummel, S., Knopff, A., Peplow, C., Roth, R., Stock, J., Strauss, E.,
Warncke, K., Winkler, C.): HLA-DPB1*04:01 protects genetically susceptible children from celiac disease
autoimmunity in the TEDDY study. Am. J. Gastroenterol. 110, 915-920 (2015)
Halama, A., Horsch, M., Kastenmüller, G., Möller, G., Kumar, P., Prehn, C., Laumen, H., Hauner, H.,
Hrabě de Angelis, M., Beckers, J., Suhre, K., Adamski, J.°: Metabolic switch during adipogenesis: From
branched chain amino acid catabolism to lipid synthesis. Arch. Biochem. Biophys. 589, 93-107 (2015)
Hansen, J.S., Zhao, X., Irmler, M., Liu, X., Hoene, M., Scheler, M., Li, Y., Beckers, J., Hrabě de Angelis,
M., Häring, H.-U., Pedersen, B.K., Lehmann, R., Xu, G.°, Plomgaard, P.°, Weigert, C.°: Type 2 diabetes
alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and
recovery. Diabetologia 58, 1845-1854 (2015)
#
#
Horsch, M. , Aguilar-Pimentel, J.A. , Bönisch, C., Côme, C., Kolster-Fog, C., Jensen, K.T., Lund, A.H.,
Lee, I., Grossman, L.I., Sinkler, C., Hüttemann, M., Bohn, E., Fuchs, H., Ollert, M., Gailus-Durner, V.,
Hrabě de Angelis, M., Beckers, J.°: Cox4i2, Ifit2, and Prdm11 mutant mice: Effective selection of genes
predisposing to an altered airway inflammatory response from a large compendium of mutant mouse lines.
PLoS ONE 10:e0134503 (2015)
Huth, C., Beuerle, S., Zierer, A., Heier, M., Herder, C., Kaiser, T., Koenig, W., Kronenberg, F., Oexle, K.,
Rathmann, W., Roden, M., Schwab, S., Seissler, J., Stöckl, D., Meisinger, C., Peters, A., Thorand, B.°:
Biomarkers of iron metabolism are independently associated with impaired glucose metabolism and type 2
diabetes: The KORA F4 Study. Eur. J. Endocrinol. 173, 643-653 (2015)
Insel, R.A., Dunne, J.L., Ziegler, A.-G.: General population screening for type 1 diabetes: Has its time
come? Curr. Opin. Endocrinol. Diabetes Obes. 22, 270-276 (2015)
page 85 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Diabetes: Pathophysiology, Prevention and Therapy
Insel, R.A.°, Dunne, J.L., Atkinson, M.A., Chiang, J.L., Dabelea, D., Gottlieb, P.A., Greenbaum, C.J., Herold,
K.C., Krischer, J.P., Lernmark, A., Ratner, R.E., Rewers, M.J., Schatz, D.A., Skyler, J.S., Sosenko, J.M.,
Ziegler, A.-G.: Staging presymptomatic type 1 diabetes: A scientific statement of JDRF, the Endocrine
Society, and the American Diabetes Association. Diabetes Care 38, 1964-1974 (2015)
Jastroch, M.°, Andersson, L.B.: When pigs fly, UCP1 makes heat. Mol. Metab. 4, 359-362 (2015)
Johansson, E., Andersson, L.B., Örnros, J., Carlsson, T., Ingeson-Carlsson, C., Liang, S., Dahlberg, J.,
Jansson, S.A., Parrillo, L., Zoppoli, P., Barila, G.O., Altschuler, D.L., Padula, D., Lickert, H., Fagman, H.,
Nilsson, M.°: Revising the embryonic origin of thyroid C cells in mice and humans. Development 142,
3519-3528 (2015)
Johnson, S.B.°, Lynch, K.F., Baxter, J., Lernmark, B., Roth, R., Simell, T., Smith, L., TEDDY Study Group
(Ziegler, A.-G., Beyerlein, A., Hummel, M., Hummel, S., Knopff, A., Peplow, C., Stock, J., Strauss, E.,
Warncke, K., Winkler, C.): Predicting later study withdrawal in participants active in a longitudinal birth
cohort study for 1 year: The TEDDY study. J. Pediatr. Psychol., DOI: 10.1093/jpepsy/jsv092 (2015)
Kälin, S., Heppner, F.L., Bechmann, I., Prinz, M., Tschöp, M.H.°, Yi, C.-X.: Hypothalamic innate immune
reaction in obesity. Nat. Rev. Endocrinol. 11, 339–351 (2015)
Karbiener, M., Glantschnig, C., Pisani, D.F., Laurencikiene, J., Dahlman, I., Herzig, S., Amri, E.Z.,
Scheideler, M.°: Mesoderm Specific Transcript (MEST) is a negative regulator of human adipocyte
differentiation. Int. J. Obes. 39, 1733-1741 (2015)
Karbiener, M., Scheideler, M.°: Microarray analysis of small non-coding RNAs. Methods Mol. Biol. 1296,
161-171 (2015)
Kastenmüller, G., Raffler, J., Gieger, C., Suhre, K.°: Genetics of human metabolism: An update. Hum.
Mol. Genet. 24, R93-R101 (2015)
Keipert, S., Kutschke, M., Lamp, D., Brachthäuser, L., Neff, F., Meyer, C.W., Oelkrug, R., Kharitonenkov,
A., Jastroch, M.°: Genetic disruption of uncoupling protein 1 in mice renders brown adipose tissue a
significant source of FGF21 secretion. Mol. Metab. 4, 537-542 (2015)
Koch, M., Baurecht, H., Ried, J.S., Rodriguez, E., Schlesinger, S., Volks, N., Gieger, C., Rückert, I.-M.,
Heinrich, L., Willenborg, C., Smith, C., Peters, A., Thorand, B., Koenig, W., Lamina, C., Jansen, H.,
Kronenberg, F., Seissler, J., Thiery, J., Rathmann, W., Schunkert, H., Erdmann, J., Barker, J., Nair, R.P.,
Tsoi, L.C., Elder, J.T., Mrowietz, U., Weichenthal, M., Mucha, S., Schreiber, S., Franke, A., Schmitt, J., Lieb,
W., Weidinger, S.°: Psoriasis and cardiometabolic traits: Modest association but distinct genetic
architectures. J. Invest. Dermatol. 135, 1283-1293 (2015)
Köhler, M., Ziegler, A.-G., Beyerlein, A.: Development of a simple tool to predict the risk of postpartum
diabetes in women with gestational diabetes mellitus. Acta Diabetol., DOI: 10.1007/s00592-015-0814-0
(2015)
page 86 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Diabetes: Pathophysiology, Prevention and Therapy
Krischer, J.P.°, Lynch, K.F., Schatz, D.A., Ilonen, J., Lernmark, A., Hagopian, W.A., Rewers, M.J., She, J.X.,
Simell, O.G., Toppari, J., Ziegler, A.-G., Akolkar, B., Bonifacio, E., TEDDY Study Group (Beyerlein, A.,
Hummel, M., Hummel, S., Knopff, A., Peplow, C., Roth, R., Stock, J., Strauss, E., Warncke, K., Winkler,
C.): The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: The TEDDY
study. Diabetologia 58, 980-987 (2015)
Krumsiek, J.#, Mittelstraß, K.#, Do, K.T., Stückler, F., Ried, J.S., Adamski, J., Peters, A., Illig, T.,
Kronenberg, F., Friedrich, N., Nauck, M., Pietzner, M., Mook-Kanamori, D.O., Suhre, K., Gieger, C.,
Grallert, H., Theis, F.J.°, Kastenmüller, G.°: Gender-specific pathway differences in the human serum
metabolome. Metabolomics 11, 1815-1833 (2015)
Lee, K.Y., Singh, M.K., Ussar, S., Wetzel, P., Hirshman, M.F., Goodyear, L.J., Kispert, A., Kahn, C.R.°:
Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism. Nat. Commun. 6:8054
(2015)
Lockie, S.H.°, Stefanidis, A., Tschöp, M.H., Oldfield, B.J.: Combination cannabinoid and opioid receptor
antagonists improves metabolic outcomes in obese mice. Mol. Cell. Endocrinol. 417, 10-19 (2015)
Lönnrot, M.°, Lynch, K., Larsson, H.E., Lernmark, A., Rewers, M., Hagopian, W., She, J., Simell, O., Ziegler,
A.-G., Akolkar, B., Krischer, J., Hyoty, H., TEDDY Study Group (Beyerlein, A., Hummel, M., Hummel, S.,
Knopff, A., Peplow, C., Roth, R., Schenkel, J., Stock, J., Strauss, E., Warncke, K., Winkler, C.): A
method for reporting and classifying acute infectious diseases in a prospective study of young children:
TEDDY. BMC Pediatr. 15:24 (2015)
Medrikova, D., Sijmonsma, T.P., Sowodniok, K., Richards, D.M., Delacher, M., Sticht, C., Gretz, N.,
Schafmeier, T., Feuerer, M., Herzig, S.°: Brown adipose tissue harbors a distinct sub-population of
regulatory T cells. PLoS ONE 10:e0118534 (2015)
Much, D., Jaschinski, H., Lack, N., Hummel, S., Fuchtenbusch, M., Hummel, M., Ziegler, A.-G.°,
Beyerlein, A.: Risk stratification in women with gestational diabetes according to and beyond current WHO
criteria. Horm. Metab. Res. 48, 16-19 (2015)
Müller, T.D., Nogueiras, R.A., Andermann, M.L., Andrews, Z.B., Anker, S.D., Argente, J., Batterham, R.,
Benoit, S.C., Bowers, C.Y., Broglio, F., Casanueva, F.F.F., D'Alessio, D., Depoortere, I., Geliebter, A.A.,
Ghigo, E., Cole, P.A., Cowley, M.A., Cummings, D.E., Dagher, A., Diano, S., Dickson, S.L., Dieguez, C.,
Granata, R., Grill, H.J., Grove, K.L., Habegger, K.M., Heppner, K.M., Heiman, M.L., Holsen, L., Holst, B.,
Inui, A., Jansson, J.O., Kirchner, H., Korbonits, M., Laferrère, B., LeRoux, C.W., López, M.D., Morin, S.,
Nakazato, M., Nass, R., Perez-Tilve, D., Pfluger, P.T., Schwartz, T.W., Seeley, R.J., Sleeman, M.W., Sun,
Y., Sussel, L., Tong, J., Thorner, M.O., van der Lely, A.J., van der Ploeg, L.H.T., Zigman, J.M., Kojima, M.,
Kangawa, K., Smith, R.G., Horvath, T., Tschöp, M.H.°: Ghrelin. Mol. Metab. 4, 437–460 (2015)
Oelkrug, R.°, Polymeropoulos, E.T., Jastroch, M.: Brown adipose tissue: Physiological function and
evolutionary significance. J. Comp. Physiol. B 185, 587-606 (2015)
page 87 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Diabetes: Pathophysiology, Prevention and Therapy
Okun, J.G., Conway, S., Schmidt, K.V., Schumacher, J., Wang, X., de Guia, R., Zota, A., Klement, J.,
Seibert, O., Peters, A., Maida, A., Herzig, S., Rose, A.J.°: Molecular regulation of urea cycle function by the
liver glucocorticoid receptor. Mol. Metab. 4, 732-740 (2015)
Perez, L.°, Wolf, K., Hennig, F., Penell, J., Basagana, X., Aguilera, I., Agis, D., Beelen, R., Brunekreef, B.,
Cyrys, J., Fuks, K.B., Adam, M., Baldassare, D., Cirach, M., Elosua, R., Dratva, J., Hampel, R., Koenig, W.,
Marrugat, J., de Faire, U., Pershagen, G., Probst-Hensch, N.M., de Nazelle, A., Nieuwenhuijsen, M.J.,
Rathmann, W., Rivera, M., Seissler, J., Schindler, C., Thierry, J., Hoffmann, B., Peters, A., Künzli, N.: Air
pollution and atherosclerosis: A cross-sectional analysis of four European cohort studies in the ESCAPE
study. Environ. Health Perspect. 123, 597-605 (2015)
Petrezselyova, S., Kinsky, S., Truban, D., Sedlacek, R., Burtscher, I., Lickert, H.°: Homology arms of
targeting vectors for gene insertions and Crispr/Cas9 technology: Size does not matter; quality control of
targeted clones does. Cell. Mol. Biol. Lett. 20, 773-787 (2016) [published online 2015]
Pfluger, P.T., Kabra, D.G., Aichler, M., Schriever, S.C., Pfuhlmann, K., Casquero García, V., Lehti, M.,
Weber, J., Kutschke, M., Rozman, J., Elrod, J.W., Hevener, A.L., Feuchtinger, A., Hrabě de Angelis, M.,
Walch, A.K., Rollmann, S.M., Aronow, B.J., Müller, T.D., Perez-Tilve, D., Jastroch, M., de Luca, M.,
Molkentin, J.D., Tschöp, M.H.°: Calcineurin links mitochondrial elongation with energy metabolism. Cell
Metab. 22, 838-850 (2015)
Preusse, M., Marr, C., Saunders, S., Maticzka, D., Lickert, H., Backofen, R., Theis, F.J.°: SimiRa: A tool to
identify coregulation between microRNAs and RNA-binding proteins. RNA Biol. 12, 998-1009 (2015)
Puff, R., D'Orlando, O., Heninger, A.K., Kühn, D., Krause, S., Winkler, C., Beyerlein, A., Bonifacio, E.,
Ziegler, A.-G.°: Compromised immune response in infants at risk for type 1 diabetes born by Caesarean
Section. Clin. Immunol. 160, 282–285 (2015)
Reis, W.L., Yi, C.-X., Gao, Y., Tschöp, M.H., Stern, J.E.°: Brain innate immunity regulates hypothalamic
arcuate neuronal activity and feeding behavior. Endocrinology 156, 1303-1315 (2015)
Roscioni, S., Heerspink, H.J.°: New nonabsorbable potassium-exchange resins in hyperkalaemia. Nat. Rev.
Nephrol. 11, 205-206 (2015)
#
#
Rottenkolber, M. , Ferrari, U. , Holland, L., Aertsen, S., Kammer, N.N., Hetterich, H., Fugmann, M.,
Banning, F., Weise, M., Sacco, V., Kohn, D., Freibothe, I., Hutter, S., Hasbargen, U., Lehmann, R.,
Grallert, H., Parhofer, K.G., Seissler, J., Lechner, A.°: The diabetes risk phenotype of young women with
recent gestational diabetes. J. Clin. Endocrinol. Metab. 100, E910-E918 (2015)
Schäfer, M., Oeing, C.U., Rohm, M., Baysal-Temel, E., Lehmann, L.H., Bauer, R., Volz, H.C., Boutros, M.,
Sohn, D., Sticht, C., Gretz, N., Eichelbaum, K., Werner, T., Hirt, M.N., Eschenhagen, T., Müller-Decker, K.,
Strobel, O., Hackert, T., Krijgsveld, J., Katus, H.A., Berriel Diaz, M., Backs, J.°, Herzig, S.°: Ataxin-10 is part
of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia. Mol. Metab. 5, 67-78
(2016) [published online 2015]
page 88 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Diabetes: Pathophysiology, Prevention and Therapy
Schlehe, J.S., Tschöp, M.H.: Unimolekulare Kombinationstherapie bei Diabetes und Adipositas - neue
therapeutische Ansätze. Diabetes akt. 13, 83-86 (2015)
Schmitz, F., Roscioni, S., Lickert, H.°: Repurposing an osteoporosis drug for β cell regeneration in diabetic
patients. Cell Metab. 22, 58-59 (2015)
Schütt, M.°, Zimmermann, A., Hood, R., Hummel, M., Seufert, J., Siegel, E., Tytko, A., Holl, R.W.:
Gender-specific effects of treatment with lifestyle, metformin or sulfonylurea on glycemic control and body
weight: A German multicenter analysis on 9108 patients. Exp. Clin. Endocrinol. Diabet. 65, 622-626 (2015)
Shariful Islam, S.M.°, Niessen, L.W., Seissler, J., Ferrari, U., Biswas, T., Islam, A., Lechner, A.: Diabetes
knowledge and glycemic control among patients with type 2 diabetes in Bangladesh. SpringerPlus 4:284
(2015)
Shariful Islam, S.M.°, Niessen, L.W., Ferrari, U., Ali, L., Seissler, J., Lechner, A.: Effects of mobile phone
SMS to improve glycemic control among patients with type 2 diabetes in Bangladesh: A prospective,
parallel-group, randomized controlled trial. Diabetes Care 38, e112-e113 (2015)
Shariful Islam, S.M.°, Lechner, A., Ferrari, U., Seissler, J., Holle, R., Niessen, L.W.: Mobile phone use and
willingness to pay for SMS for diabetes in Bangladesh. J. Public Health 38, 163-169 (2016) [published online
2015]
Smith, L.B.°, Lynch, K.F., Baxter, J., Lernmark, B., Roth, R., Simell, T., Johnson, S.B., TEDDY Study Group
(Ziegler, A.-G., Beyerlein, A., Henneberger, L., Hummel, M., Hummel, S., Knopff, A., Krause, S.,
Peplow, C., Pflüger, M., Roth, R., Schenkel, J., Stock, J., Strauss, E., Warncke, K., Winkler, C.): Factors
associated with maternal-reported actions to prevent type 1 diabetes in the first year of the TEDDY study.
Diabetes Care 37, 325-331 (2014)
Steck, A.K.°, Vehik, K., Bonifacio, E., Lernmark, A., Ziegler, A.-G., Hagopian, W.A., She, J., Simell, O.,
Akolkar, B., Krischer, J., Schatz, D., Rewers, M.J., TEDDY Study Group (Beyerlein, A., Hummel, M.,
Hummel, S., Knopff, A., Peplow, C., Roth, R., Stock, J., Strauss, E., Warncke, K., Winkler, C.):
Predictors of progression from the appearance of islet autoantibodies to early childhood diabetes: The
Environmental Determinants of Diabetes in the Young (TEDDY). Diabetes Care 38, 808-813 (2015)
#
#
Steinbrück, L. , Gustems, M. , Medele, S., Schulz, T.F., Lutter, D., Hammerschmidt, W.°: K1 and K15 of
Kaposi sarcoma-associated herpes virus are partial functional homologues of latent membrane protein 2A of
Epstein-Barr virus. J. Virol. 89, 7248-7261 (2015)
Stemmer, K., Zani, F., Habegger, K.M., Neff, C., Kotzbeck, P., Bauer, M., Yalamanchilli, S., Azad, A.,
Lehti, M., Martins, P.J., Müller, T.D., Pfluger, P.T., Seeley, R.J.°: FGF21 is not required for glucose
homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice. Diabetologia 58,
2414-2423 (2015)
page 89 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Diabetes: Pathophysiology, Prevention and Therapy
Stiel, A.C., Dean-Ben, X.L., Jiang, Y., Ntziachristos, V., Razansky, D., Westmeyer, G.G.°: High-contrast
imaging of reversibly switchable fluorescent proteins via temporally unmixed multispectral optoacoustic
tomography. Opt. Lett. 40, 367-370 (2015)
Stoy, C., Sundaram, A., Rios Garcia, M., Wang, X., Seibert, O., Zota, A., Wendler, S., Männle, D., Hinz, U.,
Sticht, C., Muciek, M., Gretz, N., Rose, A.J., Greiner, V., Hofmann, T.G., Bauer, A., Hoheisel, J., Berriel
Diaz, M., Gaida, M.M., Werner, J., Schafmeier, T., Strobel, O.°, Herzig, S.°: Transcriptional co-factor
Transducin Beta-Like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy. EMBO Mol. Med. 7,
1048-1062 (2015)
Suhre, K., Raffler, J., Kastenmüller, G.: Biochemical insights from population studies with genetics and
metabolomics. Arch. Biochem. Biophys. 589, 168-176 (2016) [published online 2015]
Tattikota, S.G., Rathjen, T., Hausser, J., Khedkar, A., Kabra, U.D., Pandey, V.K., Sury, M., Wessels, H.H.,
Mollet, I.G., Eliasson, L., Selbach, M., Zinzen, R.P., Zavolan, M., Kadener, S., Tschöp, M.H., Jastroch, M.,
Friedländer, M.R., Poy, M.N.°: MiR-184 regulates pancreatic β-cell function according to glucose
metabolism. J. Biol. Chem. 290, 20284-20294 (2015)
Thiele, I.°, Linseisen, J., Meisinger, C., Schwab, S., Huth, C., Peters, A., Perz, S., Meitinger, T.,
Kronenberg, F., Lamina, C., Thiery, J., Koenig, W., Rathmann, W., Kääb, S., Then, C., Seissler, J.,
Thorand, B.: Associations between calcium and vitamin D supplement use as well as their serum
concentrations and subclinical cardiovascular disease phenotypes. Atherosclerosis 241, 743-751 (2015)
Tönjes, A.#, Scholz, M.#, Breitfeld, J., Marzi, C., Grallert, H., Gross, A., Ladenvall, C., Schleinitz, D., Krause,
K.P., Kirsten, H., Laurila, E., Kriebel, J., Thorand, B., Rathmann, W., Groop, L.C., Prokopenko, I., Isomaa,
B., Beutner, F., Kratzsch, J.K., Thiery, J.J., Faßhauer, M., Klöting, N., Gieger, C., Blüher, M., Stumvoll,
M.W.°, Kovacs, P.°: Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the
regulation of circulating serum chemerin. PLoS Genet. 10:e1004854 (2015)
Um, S.H., Sticker-Jantscheff, M., Chau, G.C., Vintersten, K., Mueller, M., Gangloff, Y.G., Adams, R.H.,
Spetz, J.F., Elghazi, L., Pfluger, P.T., Pende, M., Bernal-Mizrachi, E., Tauler, A., Tschöp, M.H., Thomas,
G., Kozma, S.C.°: S6K1 controls pancreatic β cell size independently of intrauterine growth restriction. J.
Clin. Invest. 125, 2736-2747 (2015)
Ussar, S.#, Griffin, N.W.#, Bezy, O.#, Fujisaka, S., Vienberg, S., Softic, S., Deng, L., Bry, L., Gordon, J.I.,
Kahn, C.R.°: Interactions between gut microbiota, host genetics and diet modulate the predisposition to
obesity and metabolic syndrome. Cell Metab. 22, 516-530 (2015)
Uusitalo, U., Liu, X., Yang, J., Aronsson, C.A., Hummel, S., Butterworth, M., Lernmark, A., Rewers, M.,
Hagopian, W., She, J.X., Simell, O., Toppari, J., Ziegler, A.-G., Akolkar, B., Krischer, J., Norris, J.M.,
Virtanen, S.M.°, TEDDY Study Group: Association of early exposure of probiotics and islet autoimmunity in
the TEDDY study. JAMA Pediatr. 170, 20-28 (2016) [published online 2015]
page 90 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Diabetes: Pathophysiology, Prevention and Therapy
Uusitalo, U., Lee, H.S., Aronsson, C.A., Yang, J., Virtanen, S.M., Norris, J.M., Agardh, D.°, TEDDY Study
Group (Ziegler, A.-G., Beyerlein, A., Hummel, M., Hummel, S., Knopff, A., Peplow, C., Roth, R., Stock,
J., Strauss, E., Warncke, K., Winkler, C.): Gluten consumption during late pregnancy and risk of celiac
disease in the offspring: The TEDDY birth cohort. Am. J. Clin. Nutr. 102, 1216-1221 (2015)
Warncke, K.°, Liptay, S., Fröhlich-Reiterer, E., Scheuing, N., Schebek, M., Wolf, J., Rohrer, T.R., Meissner,
T., Holl, R.W.: Vascular risk factors in children, adolescents, and young adults with type 1 diabetes
complicated by celiac disease: Results from the DPV initiative. Pediatr. Diabetes 17, 191-198 (2016)
[published online 2015]
Williams, A.J.°, Lampasona, V., Schlosser, M., Mueller, P.W., Pittman, D.L., Winter, W.E., Akolkar, B., Wyatt,
R., Brigatti, C., Krause, S., Achenbach, P.: Detection of antibodies directed to the N-terminal region of GAD
is dependent on assay format and contributes to differences in the specificity of GAD autoantibody assays
for type 1 diabetes. Diabetes 64, 3239-3246 (2015)
Williams, A.J.°, Lampasona, V., Wyatt, R., Brigatti, C., Gillespie, K.M., Bingley, P.J., Achenbach, P.°:
Reactivity to N-terminally truncated GAD65(96-585) identifies GAD autoantibodies that are more closely
associated with diabetes progression in relatives of patients with type 1 diabetes. Diabetes 64, 3247-3252
(2015)
#
#
Willmann, S. , Müller, N.S. , Engert, S., Sterr, M., Burtscher, I., Raducanu, A., Irmler, M., Beckers, J.,
Sass, S., Theis, F.J., Lickert, H.°: The global gene expression profile of the secondary transition during
pancreatic development. Mech. Dev. 139, 51-64 (2016) [published online 2015]
Xie, T.Y., Ngo, S.T., Veldhuis, J.D., Jeffery, P.L., Chopin, L.K., Tschöp, M.H., Waters, M.J., Tolle, V.,
Epelbaum, J., Chen, C.C., Steyn, F.J.: Effect of deletion of ghrelin-o-acyltransferase on the pulsatile release
of growth hormone in mice. J. Neuroendocrinol. 27, 872-886 (2015)
Yang, J.°, Lynch, K.F., Uusitalo, U.M., Foterek, K., Hummel, S., Silvis, K., Andrén Aronsson, C., Riikonen,
A., Rewers, M., She, J.X., Ziegler, A.-G., Simell, O.G., Toppari, J., Hagopian, W.A., Lernmark, A., Akolkar,
B., Krischer, J.P., Norris, J.M., Virtanen, S.M., Johnson, S.B., TEDDY Study Group (Beyerlein, A., Hummel,
M., Knopff, A., Peplow, C., Roth, R., Stock, J., Strauss, E., Warncke, K., Winkler, C.): Factors associated
with longitudinal food record compliance in a paediatric cohort study. Public Health Nutr. 19, 804-813 (2016)
[published online 2015]
page 91 of 213
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#
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° corresponding authors
HMGU authors are given in bold letters
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Aguilera, F.°, Orlandi, F., Oteros, J., Bonofiglio, T., Fornaciari, M.: Bioclimatic characterisation of the
Mediterranean region: Future climate projections for Spain, Italy and Tunisia. Ital. J. Agrometeorol. 20, 45-58
(2015)
Ahlgrim, C., Gutermuth, J., Onell, A., Borres, M.P., Schäffner, I., Darsow, U., Pfab, F., Brockow, K., Ring,
J., Behrendt, H., Jakob, T., Huss-Marp, J.°: Comparison of molecular multiplex and singleplex analysis of
IgE to grass pollen allergens in untreated German grass pollen-allergic patients. J. Invest. Allergol. Clin.
Immunol. 25, 190-195 (2015)
Amaral, A.F., Newson, R.B., Abramson, M.J., Antò, J.M., Bono, R., Corsico, A.G., de Marco, R., Demoly, P.,
Forsberg, B., Gislason, T., Heinrich, J., Huerta, I., Janson, C., Jõgi, R., Kim, J.L., Maldonado, J.A.,
Martinez-Moratalla Rovira, J., Neukirch, C., Nowak, D., Pin, I., Probst-Hensch, N., Raherison-Semjen, C.,
Svanes, C., Urrutia Landa, I., van Ree, R., Versteeg, S.A., Weyler, J., Zock, J.P., Burney, P.G., Jarvis, D.L.:
Changes in IgE sensitization and total IgE levels over 20 years of follow-up. J. Allergy Clin. Immunol. (2015)
Amaral, A.F.°, Minelli, C., Guerra, S., Wjst, M., Probst-Hensch, N., Pin, I., Svanes, C., Janson, C., Heinrich,
J., Jarvis, D.L.: The locus C11orf30 increases susceptibility to poly-sensitization. Allergy 70, 328-333 (2015)
André, P., Prele, C.M., Vierkotten, S., Carnesecchi, S., Donati, Y., Chambers, R.C., Pache, J., Crestani, B.,
Barazzone-Argiroffo, C., Königshoff, M., Laurent, G.J., Irminger-Finger, I.°: BARD1 mediates TGF-β
signaling in pulmonary fibrosis. Respir. Res. 16:118 (2015)
Artigas, M.S., Wain, L.V., Miller, S., Kheirallah, A.K., Huffman, J.E., Ntalla, I., Shrine, N., Obeidat, M.,
Trochet, H., McArdle, W.L., Alves, A.C., Hui, J., Zhao, J.H., Joshi, P.K., Teumer, A., Albrecht, E., Imboden,
M., Rawal, R., Lopez, L.M., Marten, J., Enroth, S., Surakka, I., Polasek, O., Lyytikäinen, L.P., Granell, R.,
Hysi, P.G., Flexeder, C., Mahajan, A., Beilby, J., Bossé, Y., Brandsma, C.A., Campbell, H., Gieger, C.,
Gläser, S., Gonzalez, J.R., Grallert, H., Hammond, C.J., Harris, S.E., Hartikainen, A.L., Heliövaara, M.,
Henderson, J., Hocking, L.J., Horikoshi, M., Hutri-Kähönen, N., Ingelsson, E., Johansson, Å, Kemp, J.P.,
Kolcic, I., Kumar, A., Lind, L., Melén, E., Musk, A.W., Navarro, P., Nickle, D.C., Padmanabhan, S., Raitakari,
O.T., Ried, J.S., Ripatti, S., Schulz, H., Scott, R.A., Sin, D.D., Starr, J.M., Viñuela, A., Völzke, H., Wild, S.H.,
Wright, A.F., Zemunik, T., Jarvis, D.L., Spector, T.D., Evans, D.M., Lehtimäki, T., Kähönen, M., Gyllensten,
U., Rudan, I., Deary, I.J., Karrasch, S., Probst-Hensch, N.M., Heinrich, J., Stubbe, B., Wilson, J.F.,
Wareham, N.J., James, A.L., Morris, A.P., Jarvelin, M.R., Hayward, C., Sayers, I., Hall, I.P., Tobin, M.D.:
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation.
6:8658 (2015)
Asl, H.F., Talukdar, H.A., Kindt, A.S.D., Jain, R.K., Ermel, R., Ruusalepp, A., Nguyen, K.H., Dobrin, R.,
Reilly, D.F., Schunkert, H., Samani, N.J., Braenne, I., Erdmann, J., Melander, O., Qi, J., Ivert, T., Skogsberg,
J., Schadt, E.E., Michoel, T., Bjorkegren, J.L.M.°, CARDIoGRAM Consortium (Döring, A., Meisinger, C.,
Meitinger, T., Peters, A., Wichmann, H.-E.): Expression quantitative trait loci acting across multiple tissues
are enriched in inherited risk for coronary artery disease. Circ. Cardiovasc. Genet. 8, 305-315 (2015)
page 92 of 213
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Avitabile, S., Odorisio, T., Madonna, S., Eyerich, S., Guerra, L., Eyerich, K., Zambruno, G., Cavani, A.°,
Cianfarani, F.°: Interleukin-22 promotes wound repair in diabetes by improving keratinocyte pro-healing
functions. J. Invest. Dermatol. 135, 2862-2870 (2015)
Bamberg, F.°, Kauczor, H.U., Weckbach, S., Schlett, C.L., Forsting, M., Ladd, S.C., Greiser, K.H., Weber,
M.A., Schulz-Menger, J., Niendorf, T., Pischon, T., Caspers, S., Amunts, K., Berger, K., Bülow, R., Hosten,
N., Hegenscheid, K., Kröncke, T., Linseisen, J., Günther, M., Hirsch, J.G., Köhn, A., Hendel, T., Wichmann,
H.-E., Schmidt, B., Jockel, K.H., Hoffmann, W., Kaaks, R., Reiser, M.F., Völzke, H.: Whole-body MR imaging
in the German National Cohort: Rationale, design, and technical background. Radiology 277, 206-220 (2015)
Bardou, O., Menou, A., François, C., Duitman, J.W., von der Thüsen, J.H., Borie, R., Sales, K.U., Mutze, K.,
Castier, Y., Sage, E.H., Liu, L., Bugge, T.H., Fairlie, D.P., Königshoff, M., Crestani, B., Borensztajn, K.S.:
Membrane-anchored serine protease matriptase is a trigger of pulmonary fibrogenesis. Am. J. Respir. Crit.
Care Med. 193, 847-860 (2016) [published online 2015]
Beelen, R.°, Hoek, G., Raaschou-Nielsen, O., Stafoggia, M., Andersen, Z.J., Weinmayr, G., Hoffmann, B.,
Wolf, K., Samoli, E., Fischer, P.H., Nieuwenhuijsen, M.J., Xun, W.W., Katsouyanni, K., Dimakopoulou, K.,
Marcon, A., Vartiainen, E., Lanki, T., Yli-Tuomi, T., Oftedal, B., Schwarze, P.E., Nafstad, P., de Faire, U.,
Pedersen, N.L., Ostenson, C.G., Fratiglioni, L., Penell, J., Korek, M., Pershagen, G., Eriksen, K.T., Overvad,
K., Sørensen, M., Eeftens, M., Peeters, P.H., Meliefste, K., Wang, M., Bueno-de-Mesquita, H.B., Sugiri, D.,
Krämer, U., Heinrich, J., de Hoogh, K., Key, T., Peters, A., Hampel, R., Concin, H., Nagel, G., Jaensch, A.,
Ineichen, A., Tsai, M.Y., Schaffner, E., Probst-Hensch, N.M., Schindler, C., Ragettli, M.S., Vilier, A.,
Clavel-Chapelon, F., Declercq, C., Ricceri, F., Sacerdote, C., Galassi, C., Migliore, E., Ranzi, A., Cesaroni,
G., Badaloni, C., Forastiere, F., Katsoulis, M., Trichopoulou, A., Keuken, M., Jedynska, A., Kooter, I.M.,
Kukkonen, J.V.K., Sokhi, R.S., Vineis, P., Brunekreef, B.: Natural-cause mortality and long-term exposure to
particle components: An analysis of 19 European cohorts within the multi-center ESCAPE project. Environ.
Health Perspect. 123, 525-533 (2015)
Bigert, C., Gustavsson, P., Straif, K., Pesch, B., Brüning, T., Kendzia, B., Schüz, J., Stücker, I., Guida, F.,
Brüske, I., Wichmann, H.-E., Pesatori, A.C., Landi, M.T., Caporaso, N., Tse, L.A., Yu, I.T., Siemiatycki, J.,
Pintos, J., Merletti, F., Mirabelli, D., Simonato, L., Jockel, K.H., Ahrens, W., Pohlabeln, H., Tardón, A.,
Zaridze, D., Field, J., 't Mannetje, A., Pearce, N., McLaughlin, J., Demers, P., Szeszenia-Dabrowska, N.,
Lissowska, J., Rudnai, P., Fabianova, E., Stanescu Dumitru, R., Bencko, V., Foretova, L., Janout, V.,
Boffetta, P., Forastiere, F., Bueno-de-Mesquita, B., Peters, S., Vermeulen, R., Kromhout, H., Olsson, A.C.°:
Lung cancer risk among cooks when accounting for tobacco smoking: S pooled analysis of case-control
studies from Europe, Canada, New Zealand, and China. J. Occup. Environ. Med. 57, 202-209 (2015)
Bölükbas, D.A., Meiners, S.°: Lung cancer nanomedicine: Potentials and pitfalls. Nanomed. 10, 3203-3212
(2015)
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Bousquet, J.°, Antò, J.M., Wickman, M., Keil, T., Valenta, R., Haahtela, T., Lodrup Carlsen, K.C., van Hage,
M., Akdis, C., Bachert, C., Akdis, M., Auffray, C., Annesi-Maesano, I., Bindslev-Jensen, C.,
Cambon-Thomsen, A., Carlsen, K.H., Chatzi, L., Forastiere, F., Garcia-Aymerich, J., Gehrig, U., Guerra, S.,
Heinrich, J., Koppelman, G.H., Kowalski, M.L., Lambrecht, B.N., Lupinek, C., Maier, D., Melén, E., Momas,
I., Palkonen, S., Pinart, M., Postma, D., Siroux, V., Smit, H.A., Sunyer, J., Wright, J., Zuberbier, T., Arshad,
S.H., Nadif, R., Thijs, C., Anderson, N., Arsanoj, A., Balardini, N., Ballereau, S., Bedbrook, A., Benet, M.,
Bergström, A., Brunekreef, B., Burte, E., Calderon, M., de Carlo, G., Demoly, P., Eller, E., Fantini, M.P.,
Hammad, H., Hohman, C., Just, J., Kerkhof, M., Kogevinas, M., Kull, I., Lau, S., Lemonnier, N., Mommers,
M., Nawijn, M.C., Neubauer, A., Oddie, S., Pellet, J., Pin, I., Porta, D., Saes, Y., Skrindo, I., Tischer, C.G.,
Torrent, M., von Hertzen, L.: Are allergic multimorbidities and IgE polysensitization associated with the
persistence or re-occurrence of foetal type 2 signalling? The MeDALL hypothesis. Allergy 70, 1062-1078
(2015)
Bousquet, J.°, Antò, J.M., Berkouk, K., Gergen, P.J., Pinto Antunes, J., Augé, P., Camuzat, T., Bringer, J.,
Mercier, J., Best, N., Bourret, R., Akdis, M., Arshad, S.H., Bedbrook, A., Berr, C., Bush, A., Cavalli, G.,
Charles, M.A., Clavel-Chapelon, F., Gillman, M., Gold, D.R., Goldberg, M., Holloway, J.W., Iozzo, P.,
Jacquemin, S., Jeandel, C., Kauffmann, F., Keil, T., Koppelman, G.H., Krauss-Etschmann, S., Kuh, D.,
Lehmann, S., Lodrup Carlsen, K.C., Maier, D., Méchali, M., Melén, E., Moatti, J.P., Momas, I., Nérin, P.,
Postma, D.S., Ritchie, K., Robine, J.M., Samolinski, B., Siroux, V., Slagboom, P.E., Smit, H.A., Sunyer, J.,
Valenta, R., van de Perre, P., Verdier, J.M., Vrijheid, M., Wickman, M., Yiallouros, P.K., Zins, M.:
Developmental determinants in non-communicable chronic diseases and ageing. Thorax 70, 595-597 (2015)
page 94 of 213
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Chronic Diseases of the Lung and Allergies
Bousquet, J.°, Schünemann, H.J., Fonseca, J., Samolinski, B., Bachert, C., Canonica, G.W., Casale, T.B.,
Cruz, A.A., Demoly, P., Hellings, P.W., Valiulis, A., Wickman, M., Zuberbier, T., Bosnic-Anticevitch, S.,
Bedbrook, A., Bergmann, K.C., Caimmi, D., Dahl, R., Fokkens, W.J., Grisle, I., Lodrup Carlsen, K.C., Mullol,
J., Muraro, A., Palkonen, S., Papadopoulos, N.G., Passalacqua, G., Ryan, D., Valovirta, E., Yorgancioglu,
A., Aberer, W., Agache, I., Adachi, M., Akdis, C.A., Akdis, M., Annesi-Maesano, I., Ansotegui, I.J., Antò, J.M.,
Arnavielle, S., Arshad, H., Baiardini, I., Baigenzhin, A.K., Barbara, C., Bateman, E.D., Beghe, B., Bel, E.H.,
Ben Kheder, A., Bennoor, K.S., Benson, M., Bewick, M., Bieber, T., Bindslev-Jensen, C., Bjermer, L., Blain,
H., Boner, A.L., Boulet, L.P., Bonini, M., Bonini, S., Bosse, I., Bourret, R., Bousquet, P.J., Braido, F., Briggs,
A.H., Brightling, C.E., Brozek, J.L., Buhl, R., Burney, P.G., Bush, A., Caballero-Fonseca, F., Calderon, M.A.,
Camargos, P.A.M., Camuzat, T., Carlsen, K.H., Carr, W., Cepeda Sarabia, A.M., Chavannes, N.H., Chatzi,
L., Chen, Y.Z., Chiron, R., Chkhartishvili, E., Chuchalin, A.G., Ciprandi, G., Cirule, I., Correia de Sousa, J.,
Cox, L., Crooks, G., Costa, D.J., Custovic, A., Dahlen, S.E., Darsow, U., de Carlo, G., de Blay, F., Dedeu,
T., Deleanu, D., Denburg, J.A., Devillier, P., Didier, A., Dinh-Xuan, A.T., Dokic, D., Douagui, H., Dray, G.,
Dubakiene, R., Durham, S.R., Dykewicz, M.S., El-Gamal, Y., Emuzyte, R., Fink Wagner, A., Fletcher, M.,
Fiocchi, A., Forastiere, F., Gamkrelidze, A., Gemicioğlu, B., Gereda, J.E., González Diaz, S., Gotua, M.,
Grouse, L., Guzman, M.A., Haahtela, T., Hellquist-Dahl, B., Heinrich, J., Horak, F., Hourihane, J., Howarth,
P., Humbert, M., Hyland, M.E., Ivancevich, J.C., Jares, E.J., Johnston, S.L., Joos, G., Jonquet, O., Jung,
K.S., Just, J., Kaidashev, I., Kalayci, O., Kalyoncu, A.F., Keil, T., Keith, P.K., Khaltaev, N., Klimek, L.,
N'Goran, B.K., Kolek, V., Koppelman, G.H., Kowalski, M.L., Kull, I., Kuna, P., Kvedariene, V., Lambrecht,
B.N., Lau, S., Larenas-Linnemann, D., Laune, D., Le, L., Lieberman, P., Lipworth, B., Li, J., Louis, R.,
Magard, Y., Magnan, A., Mahboub, B., Majer, I., Makela, M.J., Manning, P., de Manuel Keenoy, E., Marshall,
G.D., Masjedi, M.R., Maurer, M., Mavale-Manuel, S., Melén, E., Melo-Gomes, E., Meltzer, E.O., Merk, H.,
Miculinic, N., Mihaltan, F., Milenkovic, B., Mohammad, Y., Molimard, M., Momas, I., Montilla-Santana, A.,
Morais-Almeida, M., Mösges, R., Namazova-Baranova, L., Naclerio, R., Neou, A., Neffen, H., Nekam, K.,
Niggemann, B., Nyembue, T.D., O'Hehir, R.E., Ohta, K., Okamoto, Y., Okubo, K., Ouedraogo, S., Paggiaro,
P., Pali-Scholl, I., Palmer, S., Panzner, P., Papi, A., Park, H.S., Pavord, I.D., Pawankar, R., Pfaar, O., Picard,
R.H., Pigearias, B., Pin, I., Plavec, D., Pohl, W., Popov, T.A., Portejoie, F., Postma, D., Potter, P., Price, D.,
Rabe, K.F., Raciborski, F., Radier Pontal, F., Repka-Ramirez, S., Robalo-Cordeiro, C., Rolland, C.,
Rosado-Pinto, J., Reitamo, S., Rodenas, F., Roman Rodriguez, M., Romano, A., Rosario, N., Rosenwasser,
L., Rottem, M., Sanchez-Borges, M., Scadding, G.K., Serrano, E., Schmid-Grendelmeier, P., Sheikh, A.,
Simons, F.E.R., Sisul, J.C., Skrindo, I., Smit, H.A., Sole, D., Sooronbaev, T., Spranger, O., Stelmach, R.,
Strandberg, T.E., Sunyer, J., Thijs, C., Todo-Bom, A., Triggiani, M., Valenta, R., Valero, A.L., van Hage, M.,
Vandenplas, O., Vezzani, G., Vichyanond, P., Viegi, G., Wagenmann, M., Walker, S.L., Wang, D.Y., Wahn,
U., Williams, D.M., Wright, J., Yawn, B.P., Yiallouros, P.K., Yusuf, O.M., Zar, H.J., Zernotti, M.E., Zhang, L.,
Zhong, N., Zidarn, M., Mercier, J.: MACVIA-ARIA sentinel network for allergic rhinitis (MASK-rhinitis): The
new generation guideline implementation. Allergy 70, 1372-1392 (2015)
page 95 of 213
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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Bousquet, J.°, Kuh, D., Bewick, M., Standberg, T., Farrell, J., Pengelly, R., Joël, M.E., Rodriguez Mañas, L.,
Mercier, J., Bringer, J., Camuzat, T., Bourret, R., Bedbrook, A., Kowalski, M.L., Samolinski, B., Bonini, S.,
Brayne, C., Michel, J.P., Venne, J., Viriot-Durandal, P., Alonso, J., Avignon, A., Ben-Shlomo, Y., Bousquet,
P.J., Combe, B.G., Cooper, R., Hardy, R., Iaccarino, G., Keil, T., Kesse-Guyot, E., Momas, I., Ritchie, K.,
Robine, J.M., Thijs, C., Tischer, C.G., Vellas, B., Zaidi, A., Alonso, F., Andersen Ranberg, K., Andreeva, V.,
Ankri, J.C., Arnavielhe, S., Arshad, H., Augé, P., Berr, C., Bertone, P., Blain, H., Blasimme, A., Buijs, G.J.,
Caimmi, D., Carriazo, A., Cesario, A., Coletta, J., Maier, D., Malva, J., Matignon, P., Melén, E., Moda, G.,
Nizinkska, A., Noguès, M., Porta, D., Postma, D., Puisieux, F., Richards, M., Robalo-Cordeiro, C., Romano,
V., Schulz, H., Scott, A., Slagter, S.N., Smit, H.A., Somekh, D., Stafford, M., Todo-Bom, A., Mercier, G.,
O'Neill, M., Pélissier, J.Y., Poethig, D., Roubille, F., Senesse, P., Suanzes, J., Touchon, J., Traver Salcedo,
V., van Beurden, M., Varraso, R., Vergara, I., Villalba-Mora, E., Wilson, N., Wouters, E., Zins, M.:
Operational definition of Active and Healthy Ageing (AHA): A conceptual framework. J. Nutr. Health Aging
19, 955-960 (2015)
Boyman, O.°, Kaegi, C., Akdis, M., Bavbek, S., Bossios, A., Chatzipetrou, A., Eiwegger, T., Firinu, D., Harr,
T., Knol, E., Matucci, A., Palomares, O., Schmidt-Weber, C.B., Simon, H.U., Steiner, U.C., Vultaggio, A.,
Akdis, C.A., Spertini, F.: EAACI IG Biologicals task force paper on the use of biologic agents in allergic
disorders. Allergy 70, 727-754 (2015)
Brenner, D.R., Amos, C.I., Brhane, Y., Timofeeva, M.N., Caporaso, N., Wang, Y., Christiani, D.C.,
Bickeböller, H., Yang, P., Albanes, D., Stevens, V.L., Gapstur, S.M., Mckay, J., Boffetta, P., Zaridze, D.,
Szeszenia-Dabrowska, N., Lissowska, J., Rudnai, P., Fabianova, E., Mates, D., Bencko, V., Foretova, L.,
Janout, V., Krokan, H.E., Skorpen, F., Gabrielsen, M.E., Vatten, L., Njølstad, I., Chen, C., Goodman, G.,
Lathrop, M., Vooder, T., Välk, K., Nelis, M., Metspalu, A., Broderick, P., Eisen, T., Wu, X., Zhang, D., Chen,
W., Spitz, M.R., Wei, Y., Su, L., Xie, D., She, J., Matsuo, K., Matsuda, F., Ito, H., Risch, A., Heinrich, J.,
Rosenberger, A., Muley, T., Dienemann, H., Field, J.K., Raji, O., Chen, Y., Gosney, J., Liloglou, T., Davies,
M.P., Marcus, M.W., McLaughlin, J., Orlow, I., Han, Y., Li, Y., Zong, X., Johansson, M., Liu, G., Tworoger,
S.S., Le Marchand, L., Henderson, B.E., Wilkens, L.R., Dai, J.C., Shen, H., Houlston, R.S., Landi, M.T.,
Brennan, P., Hung, R.J.°: Identification of lung cancer histology-specific variants applying Bayesian
framework variant prioritization approaches within the TRICL and ILCCO consortia. Carcinogenesis 36,
1314-1326 (2015)
Brüske, I.°, Pei, Z., Thiering, E., Flexeder, C., Berdel, D., von Berg, A., Koletzko, S., Bauer, C.P.,
Hoffmann, B., Heinrich, J., Schulz, H.: Caesarean Section has no impact on lung function at the age of 15
years. Pediatr. Pulmonol. 50, 1262-1269 (2015)
Burgstaller, G.°, Vierkotten, S., Lindner, M., Königshoff, M., Eickelberg, O.: Multidimensional
immunolabeling and 4D time-lapse imaging of vital ex vivo lung tissue. Am. J. Physiol. Lung Cell Mol.
Physiol. 309, L323-L332 (2015)
Burns, J., Mason, C., Müller, N.°, Ohlander, J., Zock, J.P., Drobnic, F., Wolfarth, B., Heinrich, J., Omenaas,
E., Stensrud, T., Nowak, D., Radon, K.: Asthma prevalence in Olympic summer athletes and the general
population: An analysis of three European countries. Respir. Med. 109, 813-820 (2015)
page 96 of 213
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#
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° corresponding authors
HMGU authors are given in bold letters
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Buters, J.T.M.°, Prank, M., Sofiev, M., Pusch, G., Albertini, R., Annesi-Maesano, I., Antunes, C., Behrendt,
H., Berger, U., Brandao, R., Celenk, S., Galan, C., Grewling, L., Jackowiak, B., Kennedy, R.,
Rantio-Lehtimaki, A., Reese, G., Sauliene, I., Smith, M., Thibaudon, M., Weber, B., Cecchi, L.: Variation of
the group 5 grass pollen allergen content of airborne pollen in relation to geographic location and time in
season. J. Allergy Clin. Immunol. 136, 87-95 (2015)
Caniard, A., Ballweg, K., Lukas, C., Yildirim, A.Ö., Eickelberg, O., Meiners, S.°: Proteasome function is
not impaired in healthy aging of the lung. Aging 7, 776-792 (2015)
Carpio, A.J.°, Oteros, J., Lora, A., Tortosa, F.S.: Effects of the overabundance of wild ungulates on natural
grassland in Southern Spain. Agrofor. Syst. 89, 637-644 (2015)
Casas, L.°, Sunyer, J., Tischer, C.G., Gehring, U., Wickman, M., García-Esteban, R., Lehmann, I., Kull, I.,
Reich, A., Lau, S., Wijga, A.H., Antò, J.M., Nawrot, T.S., Heinrich, J., Keil, T.O., Torrent, M.: Early-life house
dust mite allergens, childhood mite sensitization, and respiratory outcomes. Allergy 70, 820–827 (2015)
Chaker, A.M., Shamji, M.H., Dumitru, F.A., Calderon, M.A., Scadding, G.W., Makatsori, M., Jones, I.L., He,
Q.A., Subramanian, K.K., Arm, J.P., Durham, S.R., Schmidt-Weber, C.B.°: Short-term subcutaneous grass
pollen immunotherapy under the umbrella of anti-IL-4: A randomized controlled trial. J. Allergy Clin. Immunol.
137, 452-461 (2016) [published online 2015]
Chen, C.M.#, Thiering, E.#, Zock, J.P., Villani, S., Olivieri, M., Modig, L., Jarvis, D., Norbäck, D., Verlato, G.,
Heinrich, J.°: Is there a threshold concentration of cat allergen exposure on respiratory symptoms in adults?
PLoS ONE 10:e0127457 (2015)
Chen, L.S.°, Hung, R.J., Baker, T., Horton, A., Culverhouse, R., Saccone, N.L., Cheng, I., Deng, B., Han, Y.,
Hansen, H.M., Horsman, J., Kim, C., Lutz, S., Rosenberger, A., Aben, K.K., Andrew, A.S., Breslau, N.,
Chang, S.C., Dieffenbach, A.K., Dienemann, H., Frederiksen, B., Han, J., Hatsukami, D.K., Johnson, E.O.,
Pande, M., Wrensch, M.R., McLaughlin, J., Skaug, V., van der Heijden, H.F.M., Wampfler, J., Wenzlaff, A.,
Woll, P.J., Zienolddiny, S., Bickeböller, H., Brenner, H., Duell, E.J., Haugen, A., Heinrich, J., Hokanson,
J.E., Hunter, D.J., Kiemeney, L.A., Lazarus, P., Le Marchand, L., Liu, G., Mayordomo, J.I., Risch, A.,
Schwartz, A.G., Teare, D., Wu, X., Wiencke, J.K., Yang, P., Zhang, Z.F., Spitz, M.R., Kraft, P., Amos, C.I.,
Bierut, L.J.: CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis - a
meta-analysis. J. Natl. Cancer Inst. 107:djv100 (2015)
Chesné, J., Schmidt-Weber, C.B., Esser-von Bieren, J.: The use of adjuvants for enhancing allergen
immunotherapy efficacy. Immunol. Allergy Clin. North. Am. 36, 125-145 (2016) [published online 2015]
Chillappagari, S., Müller, C., Mahavadi, P., Guenther, A., Nahrlich, L., Rosenblum, J., Rubin, B.K., Henke,
M.O.°: A small molecule neutrophil elastase inhibitor, KRP-109, inhibits cystic fibrosis mucin degradation. J.
Cyst. Fibros., DOI: 10.1016/j.jcf.2015.10.008 (2015)
Chillappagari, S., Preuss, J., Licht, S., Müller, C., Mahavadi, P., Sarode, G., Vogelmeier, C., Guenther, A.,
Nahrlich, L., Rubin, B.K., Henke, M.O.°: Altered protease and antiprotease balance during a COPD
exacerbation contributes to mucus obstruction. Respir. Res. 16:85 (2015)
page 97 of 213
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#
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° corresponding authors
HMGU authors are given in bold letters
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Chillappagari, S., Venkatesan, S., Garapati, V., Mahavadi, P., Munder, A., Seubert, A., Sarode, G.,
Guenther, A., Schmeck, B.T., Tuemmler, B., Henke, M.O.°: Impaired TLR4 and HIF expression in cystic
fibrosis bronchial epithelial cells downregulates hemeoxygenase-1 and alters iron homeostasis in vitro. Am.
J. Physiol. Lung Cell Mol. Physiol. 307, L791-L799 (2014)
Conde, J.#, Tian, F.#, Hernandez, Y., Bao, C., Baptista, P.V., Cui, D., Stöger, T.°, de la Fuente, J.M.°:
RNAi-based glyconanoparticles trigger apoptotic pathways for in vitro and in vivo enhanced cancer-cell
killing. Nanoscale 7, 9083-9091 (2015)
Conlon, T.M., Bartel, J., Ballweg, K., Günter, S., Prehn, C., Krumsiek, J., Meiners, S., Theis, F.J.,
Adamski, J., Eickelberg, O., Yildirim, A.Ö.°: Metabolomics screening identifies reduced L-carnitine to be
associated with progressive emphysema. Clin. Sci. 130, 273-287 (2015)
Cyrys, J.°, Peters, A., Soentgen, J., Gu, J., Wichmann, H.-E.: Umweltzonen. Umweltmed. Hygiene
Arbeitsmed. 20, 33-57 (2015)
D'Amato, G.°, Holgate, S.T., Pawankar, R., Ledford, D.K., Cecchi, L., Al-Ahmad, M., Al-Enezi, F., Al-Muhsen,
S., Ansotegui, I.J., Baena-Cagnani, C.E., Baker, D.J., Bayram, H., Bergmann, K.C., Boulet, L.P., Buters,
J.T.M., D'Amato, M., Dorsano, S., Douwes, J., Finlay, S.E., Garrasi, D., Gomez, M., Haahtela, T., Halwani,
R., Hassani, Y., Mahboub, B., Marks, G.B., Michelozzi, P., Montagni, M., Nunes, C., Oh, J.J., Popov, T.A.,
Portnoy, J., Ridolo, E., Rosario, N., Rottem, M., Sanchez-Borges, M., Sibanda, E., Sienra-Monge, J.J.,
Vitale, C., Annesi-Maesano, I.: Meteorological conditions, climate change, new emerging factors, and
asthma and related allergic disorders. A statement of the World Allergy Organization. World Allergy Organiz.
J. 8:25 (2015)
Dau, T., Sarker, R.S., Yildirim, A.Ö., Eickelberg, O., Jenne, D.°: Autoprocessing of neutrophil elastase
near its active site reduces the efficiency of natural and synthetic elastase inhibitors. Nat. Commun. 6:6722
(2015)
de Marco, R.°, Marcon, A., Rossi, A., Antò, J.M., Cerveri, I., Gislason, T., Heinrich, J., Janson, C., Jarvis, D.,
Kuenzli, N., Leynaert, B., Probst-Hensch, N., Svanes, C., Wjst, M., Burney, P.: Asthma, COPD and overlap
syndrome: A longitudinal study in young European adults. Eur. Respir. J. 46, 671-679 (2015)
den Dekker, H.T., Sonnenschein-van der Voort, A.M., de Jongste, J.C., Anessi-Maesano, I., Arshad, S.H.,
Barros, H., Beardsmore, C.S., Bisgaard, H., Phar, S.C., Craig, L., Devereux, G., van der Ent, C.K.,
Esplugues, A., Fantini, M.P., Flexeder, C., Frey, U.H., Forastiere, F., Gehring, U., Gori, D., van der Gugten,
A.C., Henderson, A.J., Heude, B., Ibarluzea, J., Inskip, H.M., Keil, T., Kogevinas, M., Kreiner-Møller, E.,
Kuehni, C.E., Lau, S., Melén, E., Mommers, M., Morales, E., Penders, J., Pike, K.C., Porta, D., Reiss, I.K.,
Roberts, G., Schmidt, A., Schultz, E.S., Schulz, H., Sunyer, J., Torrent, M., Vassilaki, M., Wijga, A.H.,
Zabaleta, C., Jaddoe, V.W., Duijts, L.°: Early growth characteristics and the risk of reduced lung function and
asthma: A meta-analysis of 25,000 children. J. Allergy Clin. Immunol. 137, 1026-1035 (2016) [published
online 2015]
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Eberlein, B.°, Huss-Marp, J., Pfab, F., Fischer, R., Franz, R., Schlich, M.-K., Leibl, M., Allertseder, V.,
Liptak, J., Kriegisch, M., Hennico, R., Latotski, J., Ebner von Eschenbach, C., Darsow, U., Buters,
J.T.M., Behrendt, H., Huber, R., Ring, J.: Influence of alpine mountain climate of Bavaria on patients with
atopic diseases: Studies at the Environmental Research Station Schneefernerhaus (UFS - Zugspitze) - a
pilot study. Clin. Transl. Allergy 4:17 (2014)
Eckers, N., Grabenhenrich, L., McBride, D., Gough, H., Reich, A., Rosenfeld, L., Niggemann, B., Siegert, S.,
Aksünger,, Wjst, M., Kulig, M., Beyer, K., Keil, T.: Frequency and development of hen's egg allergy in early
childhood in Germany: The EuroPrevall birth cohort. Allergologie 38, 507-515 (2015)
Esser-von Bieren, J., Volpe, B., Sutherland, D.B., Bürgi, J., Verbeek, J.S., Marsland, B.J., Urban, J.F.,
Harris, N.L.°: Immune antibodies and helminth products drive CXCR2-dependent macrophage-myofibroblast
crosstalk to promote intestinal repair. PLoS Pathog. 11:e1004778 (2015)
Eyerich, K.°, Eyerich, S.: Th22 cells in allergic disease. Allergo J. Int. 24, 1-7 (2015)
Eyerich, K., Eyerich, S., Biedermann, T.: The multi-modal immune pathogenesis of atopic eczema. Trends
Immunol. 36, 788–801 (2015)
Eyerich, S.°: Molekulare Signaturen zur besseren Unterscheidung : Psoriasis und Ekzem - was wir von
doppelt betroffenen Patienten lernen können. Haut 26, 24-30 (2015)
Felix, J.F., Bradfield, J.P., Monnereau, C., van der Valk, R.J., Stergiakouli, E., Chesi, A., Gaillard, R.,
Feenstra, B., Thiering, E., Kreiner-Møller, E., Mahajan, A., Pitkänen, N., Joro, R., Cavadino, A., Huikari, V.,
Franks, S., Groen-Blokhuis, M.M., Cousminer, D.L., Marsh, J.A., Lehtimäki, T., Curtin, J.A., Vioque, J.,
Ahluwalia, T.S., Myhre, R., Price, T.S., Vilor-Tejedor, N., Yengo, L., Grarup, N., Ntalla, I., Ang, W., Atalay,
M., Bisgaard, H., Blakemore, A.I., Bonnefond, A., Carstensen, L., Eriksson, J., Flexeder, C., Franke, L.,
Geller, F., Geserick, M., Hartikainen, A.L., Haworth, C.M., Hirschhorn, J.N., Hofman, A., Holm, J.C.,
Horikoshi, M., Hottenga, J.J., Huang, J., Kadarmideen, H.N., Kähönen, M., Kiess, W., Lakka, H.M., Lakka,
T.A., Lewin, A.M., Liang, L., Lyytikäinen, L.P., Ma, B., Magnus, P., McCormack, S.E., McMahon, G., Mentch,
F.D., Middeldorp, C.M., Murray, C.S., Pahkala, K., Pers, T.H., Pfäffle, R., Postma, D.S., Power, C., Simpson,
A., Sengpiel, V., Tiesler, C.M., Torrent, M., Uitterlinden, A.G., van Meurs, J.B., Vinding, R., Waage, J.,
Wardle, J., Zeggini, E., Zemel, B.S., Dedoussis, G.V., Pedersen, O., Froguel, P., Sunyer, J., Plomin, R.,
Jacobsson, B., Hansen, T., Gonzalez, J.R., Custovic, A., Raitakari, O.T., Pennell, C.E., Widen, E.,
Boomsma, D.I., Koppelman, G.H., Sebert, S., Jarvelin, M.R., Hyppönen, E., McCarthy, M.I., Lindi, V., Harri,
N., Körner, A., Bønnelykke, K., Heinrich, J., Melbye, M., Rivadeneira, F., Hakonarson, H., Ring, S.M., Smith,
G.D., Sørensen, T.I., Timpson, N.J., Grant, S.F.A., Jaddoe, V.W.: Genome-wide association analysis
identifies three new susceptibility loci for childhood body mass index. Hum. Mol. Genet. 25, 389-403 (2016)
[published online 2015]
Fernandez, I.E., Heinzelmann, K., Verleden, S., Eickelberg, O.°: Characteristic patterns in the fibrotic lung.
Comparing idiopathic pulmonary fibrosis with chronic lung allograft dysfunction. Ann. Am. Thorac. Soc. 12,
S34-S41 (2015)
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° corresponding authors
HMGU authors are given in bold letters
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Flexeder, C., Thiering, E., von Berg, A., Berdel, D., Hoffmann, B., Koletzko, S., Bauer, C.P., Koletzko, B.,
Heinrich, J.°, Schulz, H.: Peak weight velocity in infancy is negatively associated with lung function in
adolescence. Pediatr. Pulmonol. 51, 147-156 (2016) [published online 2015]
Fuertes, E., Bracher, J., Flexeder, C., Markevych, I., Klümper, C., Hoffmann, B., Krämer, U., von Berg, A.,
Bauer, C.P., Koletzko, S., Berdel, D., Heinrich, J., Schulz, H.°: Long-term air pollution exposure and lung
function in 15 year-old adolescents living in an urban and rural area in Germany: The GINIplus and LISAplus
cohorts. Int. J. Hyg. Environ. Health 218, 656-665 (2015)
Fuertes, E.°, Standl, M., von Berg, A., Lehmann, I., Hoffman, B., Bauer, C.P., Koletzko, S., Berdel, D.,
Heinrich, J.: Parental allergic disease before and after child birth poses similar risk for childhood allergies.
Allergy 70, 873-876 (2015)
Gabrys, L.°, Thiel, C., Tallner, A., Wilms, B., Müller, C., Kahlert, D., Jekauc, D., Frick, F., Schulz, H.,
Sprengeler, O., Hey, S., Kobel, S., Vogt, L.: Akzelerometrie zur Erfassung körperlicher Aktivität:
Empfehlungen zur Methodik. Sportwissenschaft 45, 1-9 (2015)
Garcia-Aymerich, J.°, Benet, M., Saeys, Y., Pinart, M., Basagana, X., Smit, H.A., Siroux, V., Just, J., Momas,
I., Ranciere, F., Keil, T., Hohmann, C., Lau, S., Wahn, U., Heinrich, J., Tischer, C.G., Fantini, M.P., Lenzi,
J., Porta, D., Koppelman, G.H., Postma, D.S., Berdel, D., Koletzko, S., Kerkhof, M., Gehring, U., Wickman,
M., Melén, E., Hallberg, J., Bindslev-Jensen, C., Eller, E., Kull, I., Lødrup Carlsen, K.C., Carlsen, K.H.,
Lambrecht, B.N., Kogevinas, M., Sunyer, J., Kauffmann, F., Bousquet, J., Antò, J.M.: Phenotyping asthma,
rhinitis and eczema in MeDALL population-based birth cohorts: An allergic comorbidity cluster. Allergy 70,
973-984 (2015)
Garzorz, N.°, Alsisi, M., Todorova, A., Atenhan, A., Thomas, J., Lauffer, F., Ring, J., Schmidt-Weber, C.B.,
Biedermann, T., Eyerich, S., Eyerich, K.: Dissecting susceptibility from exogenous triggers: The model of
Alopecia areata and associated inflammatory skin diseases. J. Eur. Acad. Dermatol. Venereol. 29,
2429–2435 (2015)
Gehring, U., Wijga, A.H., Hoek, G., Bellander, T., Berdel, D., Brüske, I., Fuertes, E., Gruzieva, O., Heinrich,
J., Hoffmann, B., de Jongste, J.C., Klümper, C., Koppelman, G.H., Korek, M., Krämer, U., Maier, D., Melén,
E., Pershagen, G., Postma, D.S., Standl, M., von Berg, A., Antò, J.M., Bousquet, J., Keil, T., Smit, H.A.,
Brunekreef, B.: Exposure to air pollution and development of asthma and rhinoconjunctivitis throughout
childhood and adolescence: A population-based birth cohort study. Lancet Resp. Med. 3, 933-942 (2015)
page 100 of 213
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° corresponding authors
HMGU authors are given in bold letters
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#
Gharib, S.A. °, Loth, D.W. , Soler Artigas, M. , Birkland, T.P., Wilk, J.B., Wain, L.V., Brody, J.A., Obeidat, M.,
Hancock, D.B., Tang, W., Rawal, R., Boezen, H.M., Imboden, M., Huffman, J.E., Lahousse, L., Alves, A.C.,
Manichaikul, A., Hui, J., Morrison, A.C., Ramasamy, A., Smith, A.V., Gudnason, V., Surakka, I., Vitart, V.,
Evans, D.M., Strachan, D.P., Deary, I.J., Hofman, A., Gläser, S., Wilson, J.F., North, K.E., Zhao, J.H.,
Heckbert, S.R., Jarvis, D.L., Probst-Hensch, N., Schulz, H., Barr, R.G., Jarvelin, M.R., O'Connor, G.T.,
Kähönen, M., Cassano, P.A., Hysi, P.G., Dupuis, J., Hayward, C., Psaty, B.M., Hall, I.P., Parks, W.C., Tobin,
M.D., London, S.J., CHARGE Consortium (Gieger, C., Illig, T.), CHARGE Consortium (Meisinger, C.,
Prokisch, H., Wichmann, H.-E.), SpiroMeta Consortium: Integrative pathway genomics of lung function and
airflow obstruction. Hum. Mol. Genet. 24, 6836-6848 (2015)
Ghosh, S.#, Vivar, J.#, Nelson, C.P., Willenborg, C., Segrè, A.V., Maekinen, V., Nikpay, M., Erdmann, J.,
Blankenberg, S., O'Donnell, C., Maerz, W., Laaksonen, R., Stewart, A.F.R., Epstein, S.E., Shah, S.H.,
Granger, C.B., Hazen, S.L., Kathiresan, S., Reilly, M.P., CARDIoGRAM Consortium (Döring, A., Meisinger,
C., Meitinger, T., Peters, A., Wichmann, H.-E.), Yang, X., Quertermous, T., Samani, N.J., Schunkert, H.,
Assimes, T.L., McPherson, R.°: Systems genetics analysis of genome-wide association study reveals novel
associations between key biological processes and coronary artery disease. Arterioscler. Thromb. Vasc.
Biol. 35, 1712-1722 (2015)
Giannou, A.D., Marazioti, A., Spella, M., Kanellakis, N.I., Apostolopoulou, H., Psallidas, L., Prijovich, Z.M.,
Vreka, M., Zazara, D.E., Lilis, L., Papaleonidopoulos, V., Kairi, C.A., Patmanidi, A.L., Giopanou, J.,
Spiropoulou, N., Harokopos, V., Aidinis, V., Spyratos, D., Teliousi, S., Papadaki, H., Taraviras, S., Snyder,
L.A., Eickelberg, O., Kardamakis, D., Iwakura, V., Feyerabend, T.B., Rodewald, H.R., Kalomenidis, L.,
Blackwell, T.S.°, Agalloti, T.°, Stathopoulos, G.T.°: Mast cells mediate malignant pleural effusion formation.
J. Clin. Invest. 125, 2317-2334 (2015)
Gilles, S.°, Beck, I., Lange, S., Ring, J., Behrendt, H., Traidl-Hoffmann, C.: Non-allergenic factors from
pollen modulate T helper cell instructing notch ligands on dendritic cells. World Allergy Organiz. J. 8:2 (2015)
Giopanou, I., Lilis, I., Papaleonidopoulos, V., Marazioti, A., Spella, M., Vreka, M., Papadaki, H.,
Stathopoulos, G.T.°: Comprehensive evaluation of nuclear factor-κΒ expression patterns in non-small cell
lung cancer. PLoS ONE 10:e0132527 (2015)
Goodhead, R.M., Johnston, B.D., Cole, P.A., Baalousha, M., Hodgson, D., Iguchi, T., Lead, J.R., Tyler,
C.R.: Does natural organic matter increase the bioavailability of cerium dioxide nanoparticles to fish?
Environ. Chem. 12, 673-682 (2015)
Gosens, I.°, Kermanizadeh, A., Jacobsen, N.R., Lenz, A.-G., Bokkers, B., de Jong, W.H., Krystek, P., Tran,
L., Stone, V., Wallin, H., Stöger, T., Cassee, F.R.: Comparative hazard identification by a single dose lung
exposure of zinc oxide and silver nanomaterials in mice. PLoS ONE 10:e0126934 (2015)
Graessel, A., Hauck, S.M., von Toerne, C., Kloppmann, E., Goldberg, T., Koppensteiner, H., Schindler,
M., Knapp, B., Krause, L., Dietz, K., Schmidt-Weber, C.B., Suttner, K.°: A combined omics approach to
generate the surface atlas of human naive CD4+ T cells during early TCR activation. Mol. Cell. Proteomics
14, 2085-2102 (2015)
page 101 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
Hamon, Y., Legowska, M., Fergelot, P., Dallet-Choisy, S., Newell, L., Vanderlynden, L., Kord Valeshabad,
A., Acrich, K., Kord, H., Charalampos, T., Morice-Picard, F., Surplice, I., Zoidakis, J., David, K., Vlahou, A.,
Ragunatha, S., Nagy, N., Farkas, K., Széll, M., Goizet, C., Schacher, B., Battino, M., Al Farraj Aldosari, A.,
Wang, X., Liu, Y., Marchand-Adam, S., Lesner, A., Kara, E., Korkmaz-Icöz, S., Moss, C., Eickholz, P., Taïeb,
A., Kavukcu, S., Jenne, D., Gauthier, F., Korkmaz, B.°: Analysis of urinary cathepsin C for diagnosing
Papillon-Lefèvre syndrome. FEBS J. 283, 498-509 (2016) [published online 2015]
Hancock, D.B.°, Reginsson, G.W., Gaddis, N.C., Chen, X., Saccone, N.L., Lutz, S.M., Qaiser, B., Sherva, R.,
Steinberg, S., Zink, F., Stacey, S.N., Glasheen, C., Chen, J., Gu, F., Frederiksen, B.N., Loukola, A.,
Gudbjartsson, D.F., Brüske, I., Landi, M.T., Bickeböller, H., Madden, P., Farrer, L.A., Kaprio, J., Kranzler,
H.R., Gelernter, J., Baker, T.B., Kraft, P., Amos, C.I., Caporaso, N.E., Hokanson, J.E., Bierut, L.J.,
Thorgeirsson, T.E., Johnson, E.O., Stefansson, K.: Genome-wide meta-analysis reveals common splice site
acceptor variant in CHRNA4 associated with nicotine dependence. Transl. Psychiatry 5:e651 (2015)
Harris, C., Flexeder, C., Thiering, E., Buyken, A., Berdel, D., Koletzko, S., Bauer, C.P., Brüske, I.,
Koletzko, B., Standl, M.°: Changes in dietary intake during puberty and their determinants: Results from the
GINIplus birth cohort study. BMC Public Health 15:841 (2015)
Hellbach, K., Yaroshenko, A., Meinel, F.G., Yildirim, A.Ö., Conlon, T.M., Bech, M., Mueller, M., Velroyen,
A., Notohamiprodjo, M., Bamberg, F., Auweter, S., Reiser, M., Eickelberg, O., Pfeiffer, F.°: In vivo dark-field
radiography for early diagnosis and staging of pulmonary emphysema. Invest. Radiol. 50, 430-435 (2015)
Herder, C.°, Bongaerts, B.W., Ouwens, D.M., Rathmann, W., Heier, M., Carstensen-Kirberg, M., Koenig, W.,
Thorand, B., Roden, M., Meisinger, C., Ziegler, D., KORA Study Group (Gieger, C., Grallert, H., Heinrich,
J., Holle, R., Leidl, R., Peters, A., Strauch, K.): Low serum omentin levels in the elderly population with
type 2 diabetes and polyneuropathy. Diabet. Med. 32, 1479-1483 (2015)
Hinkofer, L.C., Hummel, A.M., Stone, J.H., Hoffman, G.S., Merkel, P.A., Spiera, E.R., St. Clair, W., McCune,
J.W., Davis, J.C., Specks, U., Jenne, D.°: Allosteric modulation of proteinase 3 activity by anti-neutrophil
cytoplasmic antibodies in granulomatosis with polyangiitis. J. Autoimmun. 59, 43-52 (2015)
Hirn, S., Haberl, N., Loza, K., Epple, M., Kreyling, W.G., Rothen-Rutishauser, B., Rehberg, M., Krombach,
F.°: Proinflammatory and cytotoxic response to nanoparticles in precision-cut lung slices. Beilstein J.
Nanotechnol. 5, 2440-2449 (2014)
Hofer, T.P., Zawada, A.M., Frankenberger, M., Skokann, K., Satzl, A.A., Gesierich, W., Schuberth, M.,
Levin, J., Danek, A., Rotter, B., Heine, G.H., Ziegler-Heitbrock, L.°: Slan-defined subsets of CD16-positive
monocytes: Impact of granulomatous inflammation and M-CSF-receptor mutation. Blood 126, 2601-2610
(2015)
page 102 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
Holm, A.T., Wulf-Johansson, H., Hvidtsen, S., Jorgensen, P.T., Schlosser, A., Pilecki, B., Ormhoj, M.,
Moeller, J.B., Johannsen, C., Baun, C., Andersen, T., Schneider, J.P., Hegermann, J., Ochs, M., Götz, A.A.,
Schulz, H., Hrabě de Angelis, M., Vestbo, J., Holmskov, U., Sorensen, G.L.°: Characterization of
spontaneous air space enlargement in mice lacking microfibrillar-associated protein 4. Am. J. Physiol. Lung
Cell Mol. Physiol. 308, L1114-L1124 (2015)
Hrabě de Angelis, M.#, Nicholson, G.#, Selloum, M.#, White, J.K.#, Morgan, H.#, Ramirez-Solis, R.#, Sorg,
T.#, Wells, S.#, Fuchs, H.#, Fray, M.#, Adams, D.J., Adams, N.C., Adler, T., Aguilar-Pimentel, J.A.,
Ali-Hadji, D., Amann, G., André, P., Atkins, S., Auburtin, A., Ayadi, A., Becker, J., Becker, L., Bedu, E.,
Bekeredjian, R., Birling, M.C., Blake, A., Bottomley, J., Bowl, M.R., Brault, V., Busch, D.H., Bussell, J.N.,
Calzada-Wack, J., Cater, H., Champy, M.F., Charles, P., Chevalier, C., Chiani, F., Codner, G.F., Combe, R.,
Cox, R.D., Dalloneau, E., Dierich, A., di Fenza, A., Doe, B., Duchon, A., Eickelberg, O., Esapa, C.T., Fertak,
L.E., Feigel, T., Emelyanova, I., Estabel, J., Favor, J., Flenniken, A.M., Gambadoro, A., Garrett, L., Gates,
H., Gerdin, A.K., Gkoutos, G.V., Greenaway, S., Glasl, L., Goetz, P., da Cruz, I.G., Götz, A., Graw, J.,
Guimond, A., Hans, W., Hicks, G., Hölter, S.M., Höfler, H., Hancock, J.M., Hoehndorf, R., Hough, T.,
Houghton, R., Hurt, A., Ivandic, B., Jacobs, H., Jacquot, S., Jones, N., Karp, N.A., Katus, H.A., Kitchen, S.,
Klein-Rodewald, T., Klingenspor, M., Klopstock, T., Lalanne, V., Leblanc, S., Lengger, C., le Marchand,
E., Ludwig, T., Lux, A., McKerlie, C., Maier, H., Mandel, J.L., Marschall, S., Mark, M., Melvin, D.G.,
Meziane, H., Micklich, K., Mittelhauser, C., Monassier, L., Moulaert, D., Müller, S., Naton, B., Neff, F.,
Nolan, P.M., Nutter, L.M., Ollert, M., Pavlovic, G., Pellegata, N.S., Peter, E., Petit-Demoulière, B., Pickard,
A., Podrini, C., Potter, P., Pouilly, L., Puk, O., Richardson, D., Rousseau, S., Quintanilla-Fend, L., Quwailid,
M.M., Rácz, I., Rathkolb, B., Riet, F., Rossant, J., Roux, M., Rozman, J., Ryder, E., Salisbury, J., Santos,
L., Schäble, K.-H., Schiller, E., Schrewe, A., Schulz, H., Steinkamp, R., Simon, M., Stewart, M., Stöger,
C., Stöger, T., Sun, M., Sunter, D., Teboul, L., Tilly, I., Tocchini-Valentini, G.P., Tost, M., Treise, I.,
Vasseur, L., Velot, E., Vogt Weisenhorn, D.M., Wagner, C., Walling, A., Wattenhofer-Donze, M., Weber, B.,
Wendling, O., Westerberg, H., Willershäuser, M., Wolf, E., Wolter, A., Wood, J., Wurst, W., Yildirim, A.Ö.,
Zeh, R., Zimmer, A., Zimprich, A., Holmes, C.#, Steel, K.P.#, Herault, Y.#, Gailus-Durner, V.#, Mallon,
A.M.#, Brown, S.D.#°: Analysis of mammalian gene function through broad-based phenotypic screens across
a consortium of mouse clinics. Nat. Genet. 47, 969-978 (2015)
page 103 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
Huffman, J.E., Albrecht, E., Teumer, A., Mangino, M., Kapur, K., Johnson, T., Kutalik, Z., Pirastu, N., Pistis,
G., Lopez, L.M., Haller, T., Salo, P., Goel, A., Li, M., Tanaka, T., Dehghan, A., Ruggiero, D., Malerba, G.,
Smith, A.V., Nolte, I.M., Portas, L., Phipps-Green, A., Boteva, L., Navarro, P., Johansson, A., Hicks, A.A.,
Polasek, O., Esko, T., Peden, J.F., Harris, S.E., Murgia, F., Wild, S.H., Tenesa, A., Tin, A., Mihailov, E.,
Grotevendt, A., Gislason, G.K., Coresh, J., D'Adamo, P., Ulivi, S., Vollenweider, P., Waeber, G., Campbell,
S., Kolcic, I., Fisher, K., Viigimaa, M., Metter, J.E., Masciullo, C., Trabetti, E., Bombieri, C., Sorice, R.,
Döring, A., Reischl, E., Strauch, K., Hofman, A., Uitterlinden, A.G., Waldenberger, M., Wichmann, H.-E.,
Davies, G., Gow, A.J., Dalbeth, N., Stamp, L., Smit, J.H., Kirin, M., Nagaraja, R., Nauck, M., Schurmann, C.,
Budde, K., Farrington, S.M., Theodoratou, E., Jula, A., Salomaa, V., Sala, C., Hengstenberg, C., Burnier, M.,
Mägi, R., Klopp, N., Kloiber, S., Schipf, S., Ripatti, S., Cabras, S., Soranzo, N., Homuth, G., Nutile, T.,
Munroe, P.B., Hastie, N., Campbell, H., Rudan, I., Cabrera, C., Haley, C., Franco, O.H., Merriman, T.R.,
Gudnason, V., Pirastu, M., Penninx, B.W., Snieder, H., Metspalu, A., Ciullo, M., Pramstaller, P.P., van Duijn,
C.M., Ferrucci, L., Gambaro, G., Deary, I.J., Dunlop, M.G., Wilson, J.F., Gasparini, P., Gyllensten, U.,
Spector, T.D., Wright, A.F., Hayward, C., Watkins, H., Perola, M., Bochud, M., Kao, W.H., Caulfield, M.,
Toniolo, D., Völzke, H., Gieger, C., Köttgen, A., Vitart, V.°: Modulation of genetic associations with serum
urate levels by body-mass-index in humans. PLoS ONE 10:e0119752 (2015)
Idler, N., Teuner, C.M., Hunger, M., Holle, R.°, Ortlieb, S., Schulz, H., Bauer, C.P., Hoffmann, U.,
Koletzko, S., Lehmann, I., von Berg, A., Berdel, D., Hoffmann, B., Schaaf, B., Heinrich, J., Wolfenstetter,
S.B.: The association between physical activity and healthcare costs in children - results from the GINIplus
and LISAplus cohort studies. BMC Public Health 15:437 (2015)
Italia, S.°, Brüske, I., Heinrich, J., Berdel, D., von Berg, A., Lehmann, I., Standl, M., Wolfenstetter, S.B.: A
longitudinal comparison of drug use among 10-year-old children and 15-year-old adolescents from the
German GINIplus and LISAplus birth cohorts. Eur. J. Clin. Pharmacol. 72, 301-310 (2016) [published online
2015]
Italia, S.°, Brand, H., Heinrich, J., Berdel, D., von Berg, A., Wolfenstetter, S.B.: Utilization of
Complementary and Alternative Medicine (CAM) among children from a German birth cohort (GINIplus):
Patterns, costs, and trends of use. BMC Complement. Altern. Med. 15:569 (2015)
Italia, S.°, Brand, H., Heinrich, J., Berdel, D., von Berg, A., Wolfenstetter, S.B.: Utilization of
self-medication and prescription drugs among 15-year-old children from the German GINIplus birth cohort.
Pharmacoepidemiol. Drug Saf. 24, 1133–1143 (2015)
Jacobsen, N.R.°, Stöger, T., van den Brule, S., Saber, A.T., Beyerle, A., Vietti, G., Mortensen, A., Szarek,
J., Budtz, H.C., Kermanizadeh, A., Banerjee, A., Ercal, N., Vogel, U., Wallin, H., Møller, P.: Acute and
subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three
laboratories. Food Chem. Toxicol. 85, 84-95 (2015)
page 104 of 213
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
#
#
Jacquemin, B. °, Siroux, V. , Sanchez, M., Carsin, A.E., Schikowski, T., Adam, M., Bellisario, V., Buschka,
A., Bono, R., Brunekreef, B., Cai, Y., Cirach, M., Clavel-Chapelon, F., Declercq, C., de Marco, R., de
Nazelle, A., Ducret-Stich, R.E., Ferretti, V.V., Gerbase, M.W., Hardy, R., Heinrich, J., Janson, C., Jarvis, D.,
Al Kanaani, Z., Keidel, D., Kuh, D., Le Moual, N., Nieuwenhuijsen, M.J., Marcon, A., Modig, L., Pin, I.,
Rochat, T., Schindler, C., Sugiri, D., Stempfelet, M., Temam, S., Tsai, M.Y., Varraso, R., Vienneau, D.,
Vierkötter, A., Hansell, A.L., Krämer, U., Probst-Hensch, N.M., Sunyer, J., Künzli, N., Kauffmann, F.: Ambient
air pollution and adult asthma incidence in six European cohorts (ESCAPE). Environ. Health Perspect. 123,
613-621 (2015)
Jaeger, T.°, Rothmaier, M., Zander, H., Ring, J., Gutermuth, J., Anliker, M.D.: Acid-coated textiles (pH
5.5-6.5) - a new therapeutic strategy for atopic eczema? Acta Derm.-Venereol. 95, 659-663 (2015)
Jansen, H., Loley, C., Lieb, W., Pencina, M.J., Nelson, C.P., Kathiresan, S., Peloso, G.M., Voight, B.F.,
Reilly, M.P., Assimes, T.L., Boerwinkle, E., Hengstenberg, C., Laaksonen, R., McPherson, R., Roberts, R.,
Thorsteinsdottir, U., Peters, A., Gieger, C., Rawal, R., CARDIoGRAM Consortium (Döring, A., Meisinger,
C., Schunkert, H.°, Meitinger, T.), Thompson, J.R., König, I.R., Vasan, R.S., Erdmann, J., Samani, N.J.:
Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk.
Atherosclerosis 241, 419-426 (2015)
Jochner, S.°, Lüpke, M., Laube, J., Weichenmeier, I., Pusch, G., Traidl-Hoffmann, C., Schmidt-Weber,
C.B., Buters, J.T.M., Menzel, A.: Seasonal variation of birch and grass pollen loads and allergen release at
two sites in the German Alps. Atmos. Environ. 122, 83-93 (2015)
Jochner, S.°, Markevych, I., Beck, I., Traidl-Hoffmann, C., Heinrich, J., Menzel, A.: The effects of short- and
long-term air pollutants on plant phenology and leaf characteristics. Environ. Pollut. 206, 382-389 (2015)
John-Schuster, G.°, Günter, S., Hager, K., Conlon, T.M., Eickelberg, O., Yildirim, A.Ö.°: Inflammaging
increases susceptibility to cigarette smoke-induced COPD. Oncotarget, DOI: 10.18632/oncotarget.4027
(2015)
Kaess, B.M., Preis, S.R., Lieb, W., Beiser, A.S., Yang, Q., Chen, T.C., Hengstenberg, C., Erdmann, J.,
Schunkert, H., Seshadri, S., Vasan, R.S., CARDIoGRAM Consortium (Döring, A., Meisinger, C., Meitinger,
T., Peters, A., Wichmann, H.-E.): Circulating brain-derived neurotrophic factor concentrations and the risk of
cardiovascular disease in the community. J. Am. Heart Assoc. 4:e001544 (2015)
Karo-Atar, D., Bordowitz, A., Wand, O., Pasmanik-Chor, M., Fernandez, I.E., Itan, M., Frenkel, R., Herbert,
D.R., Finkelman, F.D., Eickelberg, O., Munitz, A.°: A protective role for IL-13 receptor α 1 in
bleomycin-induced pulmonary injury and repair. Mucosal Immunol. 9, 240-253 (2016) [published online 2015]
Kauke, T., Kneidinger, N., Martin, B., Dick, A., Schneider, C., Schramm, R., Meimarakis, G., Preissler, G.,
Eickelberg, O., von Dossow, V., Behr, J., Hatz, R.A., Neurohr, C., Winter, H.: Bronchiolitis obliterans
syndrome due to donor-specific HLA-antibodies. Tissue Antigens 86, 178-185 (2015)
page 105 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
Keller, I.E., Vosyka, O., Takenaka, S., Kloß, A., Dahlmann, B., Willems, L.I., Verdoes, M., Overkleeft, H.S.,
Marcos, E., Adnot, S., Hauck, S.M., Ruppert, C., Günther, A., Herold, S., Ohno, S., Adler, H., Eickelberg,
O., Meiners, S.°: Regulation of immunoproteasome function in the lung. Sci. Rep. 5:10230 (2015)
Kessler, T.#, Zhang, L.#, Liu, Z., Yin, X., Huang, Y., Wang, Y., Fu, Y., Mayr, M., Ge, Q., Xu, Q., Zhu, Y.,
Wang, X., Schmidt, K.J., de Wit, C., Erdmann, J., Schunkert, H., Aherrahrou, Z#°, Kong, W.#°, German
Mouse Clinic Consortium (Adamski, J., Adler, T., Aguilar-Pimentel, J.A., Amarie, O.V., Becker, L.,
Beckers, J., Brachthäuser, L., Busch, D.H., Calzada-Wack, J., Eickelberg, O., Fuchs, H.,
Gailus-Durner, V., Garrett, L., Graw, J., Hans, W., Hölter, S.M., Horsch, M., Hrabě de Angelis, M.,
Janik, D., Klein-Rodewald, T., Klingenspor, M., Klopstock, T., Lengger, C., Leuchtenberger, S., Maier,
H., Moreth, K., Neff, F., Ollert, M., Prehn, C., Puk, O., Rathkolb, B., Rozman, J., Steinkamp, R., Stöger,
C., Stöger, T., Vernaleken, A.M., Yildirim, A.Ö., Wurst, W., Zimprich, A.): ADAMTS-7 inhibits
re-endothelialization of injured arteries and promotes vascular remodeling via cleavage of thrombospondin-1.
Circulation 131, 1191-1201 (2015)
Kinnersley, B., Labussière, M., Holroyd, A., di Stefano, A.L., Broderick, P., Vijayakrishnan, J., Mokhtari, K.,
Delattre, J.Y., Gousias, K., Schramm, J., Schoemaker, M.J., Fleming, S.J., Herms, S., Heilmann, S.,
Schreiber, S., Wichmann, H.-E., Nöthen, M.M., Swerdlow, A., Lathrop, M., Simon, M., Bondy, M., Sanson,
M., Houlston, R.S.°: Genome-wide association study identifies multiple susceptibility loci for glioma. Nat.
Commun. 6:8559 (2015)
Klümper, C.°, Krämer, U.°, Lehmann, I., von Berg, A., Berdel, D., Herberth, G., Beckmann, C., Link, E.,
Heinrich, J., Hoffmann, B., Schins, R.P., GINIplus Study Group (Wichmann, H.-E.), LISAplus Study Group
(Sausenthaler, S., Chen, C.M., Schnappinger, M.): Air pollution and cytokine responsiveness in asthmatic
and non-asthmatic children. Environ. Res. 138, 381-390 (2015)
Kneidinger, N., Giessen, C., von Wulffen, W., Milger, K., Schramm, R., Jaeger, G., Nitschko, H., Striebinger,
H., Behr, J., Neurohr, C.: Trip to immunity: Resistant cytomegalovirus infection in a lung transplant recipient.
Int. J. Infect. Dis. 28, 140-142 (2014)
Krauss-Etschmann, S., Meyer, K.F., Dehmel, S., Hylkema, M.N.°: Inter- and transgenerational epigenetic
inheritance: Evidence in asthma and COPD? Clin. Epigenet. 7:53 (2015)
Kreuter, M.°, Herth, F., Wacker, M., Leidl, R., Hellmann, A., Pfeifer, M., Behr, J., Witt, S., Kauschka, D.,
Mall, M., Günther, A., Markart, P.: Exploring clinical and epidemiological characteristics of interstitial lung
diseases: Rationale, aims, and design of a nationwide prospective registry - the EXCITING-ILD registry.
Biomed Res. Int. 2015:123876 (2015)
Kreyling, W.G.°, Abdelmonem, A.M., Ali, Z., Alves, F., Geiser, M., Haberl, N., Hartmann, R., Hirn, S., de
Aberasturi, D.J., Kantner, K., Khadem-Saba, G., Montenegro, J.M., Rejman, J., Rojo, T., de Larramendi,
I.R., Ufartes, R., Wenk, A., Parak, W.J.°: In vivo integrity of polymer-coated gold nanoparticles. Nat.
Nanotechnol. 10, 619-623 (2015)
page 106 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
#
#
Kreymborg, K.G. , Haak, S. , Murali, R., Wei, J., Waitz, R., Gasteiger, G., Savage, P., van den Brink, M.R.,
Allison, J.P.°: Ablation of B7-H3 but not B7-H4 results in highly increased tumor burden in a murine model of
spontaneous prostate cancer. Cancer Immunol. Res. 3, 849-854 (2015)
Kühnisch, J., Thiering, E., Kratzsch, J., Heinrich-Weltzien, R., Hickel, R., Heinrich, J., GINIplus Study
Group (Chen, C.M., Rzehak, P., Sausenthaler, S., Schnappinger, M., Wichmann, H.-E., Zutavern, A.),
LISAplus Study Group: Elevated serum 25(OH)-vitamin D levels are negatively correlated with molar-incisor
hypomineralization. J. Dent. Res. 94, 381-387 (2015)
Laurent, S.A., Hoffmann, F.S., Kuhn, P.H., Cheng, Q., Chu, Y., Schmidt-Supprian, M., Hauck, S.M., Schuh,
E., Krumbholz, M., Rübsamen, H., Wanngren, J., Khademi, M., Olsson, T., Alexander, T., Hiepe, F., Pfister,
H.W., Weber, F., Jenne, D., Wekerle, H., Hohlfeld, R., Lichtenthaler, S.F., Meinl, E.°: γ-secretase directly
sheds the survival receptor BCMA from plasma cells. Nat. Commun. 6:7333 (2015)
Lehmann, S.#, Hiller, J.#, van Bergenhenegouwen, J., Knippels, L.M., Garssen, J., Traidl-Hoffmann, C.°: In
vitro evidence for immune-modulatory properties of non-digestible oligosaccharides: Direct effect on human
monocyte derived dendritic cells. PLoS ONE 10:e0132304 (2015)
Lenart, M., Rutkowska-Zapala, M., Baj-Krzyworzeka, M., Szatanek, R., Węglarczyk, K., Smallie, T.,
Ziegler-Heitbrock, L., Zembala, M., Siedlar, M.°: Hyaluronan carried by tumor-derived microvesicles
++
induces IL-10 production in classical CD14 CD16 monocytes via PI3K/Akt/mTOR-dependent signalling
pathway. Immunobiology, DOI: 10.1016/j.imbio.2015.06.019 (2015)
page 107 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
#
#
#
#
#
Locke, A.E. , Kahali, B. , Berndt, S.I. , Justice, A.E. , Pers, T.H. , Day, F.R., Powell, C.A., Vedantam, S.,
Buchkovich, M.L., Yang, J., Croteau-Chonka, D.C., Esko, T., Fall, T., Ferreira, T., Gustafsson, S., Kutalik, Z.,
Luan, J., Mägi, R., Randall, J.C., Winkler, T.W., Wood, A.R., Workalemahu, T., Faul, J.D., Smith, J.A., Hua
Zhao, J., Zhao, W., Chen, J., Fehrmann, R.S.N., Hedman, A.K., Karjalainen, J., Schmidt, E.M., Absher, D.,
Amin, N., Anderson, D., Beekman, M., Bolton, J.L., Bragg-Gresham, J.L., Buyske, S., Demirkan, A., Deng,
G., Ehret, G.B., Feenstra, B., Feitosa, M.F., Fischer, K., Goel, A., Gong, J., Jackson, A.U., Kanoni, S.,
Kleber, M.E., Kristiansson, K., Lim, U., Lotay, V., Mangino, M., Mateo Leach, I., Medina-Gomez, C.,
Medland, S.E., Nalls, M.A., Palmer, C.D., Pasko, D., Pechlivanis, S., Peters, M.J., Prokopenko, I., Shungin,
D., Stancáková, A., Strawbridge, R.J., Ju Sung, Y., Tanaka, T., Teumer, A., Trompet, S., van der Laan,
S.W., van Setten, J., van Vliet-Ostaptchouk, J.V., Wang, Z., Yengo, L., Zhang, W., Isaacs, A., Albrecht, E.,
Ärnlöv, J., Arscott, G.M., Attwood, A.P., Bandinelli, S., Barrett, A., Bas, I.N., Bellis, C., Bennett, A.J., Berne,
C., Blagieva, R., Blüher, M., Böhringer, S., Bonnycastle, L.L., Böttcher, Y., Boyd, H.A., Bruinenberg, M.,
Caspersen, I.H., Chen, Y.D.I., Clarke, R., Daw, E.W., de Craen, A.J., Delgado, G., Dimitriou, M., Doney,
A.S., Eklund, N., Estrada, K., Eury, E., Folkersen, L., Fraser, R.M., Garcia, M.E., Geller, F., Giedraitis, V.,
Gigante, B., Go, A.S., Golay, A., Goodall, A.H., Gordon, S.D., Gorski, M., Grabe, H.J., Grallert, H.,
Grammer, T.B., Gräßler, J., Grönberg, H., Groves, C.J., Gusto, G., Haessler, J., Hall, P., Haller, T.,
Hallmans, G., Hartman, C.A., Hassinen, M., Hayward, C., Heard-Costa, N.L., Helmer, Q., Hengstenberg, C.,
Holmen, O.L., Hottenga, J.J., James, A.L., Jeff, J.M., Johansson, A., Jolley, J., Juliusdottir, T., Kinnunen, L.,
Koenig, W., Koskenvuo, M., Kratzer, W., Laitinen, J., Lamina, C., Leander, K., Lee, N.R., Lichtner, P., Lind,
L., Lindstrom, J., Lo, K.S., Lobbens, S., Lorbeer, R., Lu, Y., Mach, F., Magnusson, P.K., Mahajan, A.,
McArdle, W.L., McLachlan, S., Menni, C., Merger, S., Mihailov, E., Milani, L., Moayyeri, A., Monda, K.L.,
Morken, M.A., Mulas, A., Müller, G., Müller-Nurasyid, M., Musk, A.W., Nagaraja, R., Nöthen, M.M., Nolte,
I.M., Pilz, S., Rayner, N.W., Renström, F., Rettig, R., Ried, J.S., Ripke, S., Robertson, N.R., Rose, L.M.,
Sanna, S., Scharnagl, H., Scholtens, S., Schumacher, F.R., Scott, W.R., Seufferlein, T., Shi, J., Smith, A.V.,
Smolonska, J., Stanton, A.V., Steinthorsdottir, V., Stirrups, K., Stringham, H.M., Sundström, J., Swertz, M.A.,
Swift, A.J., Syvanen, A.C., Tan, S.T., Tayo, B.O., Thorand, B., Thorleifsson, G., Tyrer, J.P., Uh, H.W.,
Vandenput, L., Verhulst, F.C., Vermeulen, S.H., Verweij, N., Vonk, J.M., Waite, L.L., Warren, H.R.,
Waterworth, D., Weedon, M.N., Wilkens, L.R., Willenborg, C., Wilsgaard, T., Wojczynski, M.K., Wong, A.,
Wright, A.F., Zhang, Q., Brennan, E.P., Choi, M., Dastani, Z., Drong, A.W., Eriksson, P., Franco-Cereceda,
A., Gådin, J.R., Gharavi, A.G., Goddard, M.E., Handsaker, R.E., Huang, J., Karpe, F., Kathiresan, S.,
Keildson, S., Kiryluk, K., Kubo, M., Lee, J.Y., Liang, L., Lifton, R.P., Ma, B., McCarroll, S.A., McKnight, A.J.,
Min, J.L., Moffatt, M.F., Montgomery, G.W., Murabito, J.M., Nicholson, G., Nyholt, D.R., Okada, Y., Perry,
J.R., Dorajoo, R., Reinmaa, E., Salem, R.M., Sandholm, N., Scott, R.A., Stolk, L., Takahashi, A., van't Hooft,
F.M., Vinkhuyzen, A.A., Westra, H.J., Zheng, W., Zondervan, K.T., Heath, A.C., Arveiler, D., Bakker, S.J.,
Beilby, J., Bergman, R.N., Blangero, J., Bovet, P., Campbell, H., Caulfield, M.J., Cesana, G., Chakravarti, A.,
Chasman, D.I., Chines, P.S., Collins, F.S., Crawford, D.C., Cupples, L.A., Cusi, D., Danesh, J., de Faire, U.,
den Ruijter, H.M., Dominiczak, A.F., Erbel, R., Erdmann, J., Eriksson, J.G., Farrall, M., Felix, S.B.,
Ferrannini, E., Ferrieres, J., Ford, I., Forouhi, N.G., Forrester, T., Franco, O.H., Gansevoort, R.T., Gejman,
P.V., Gieger, C., Gottesman, O., Gudnason, V., Gyllensten, U., Hall, A.S., Harris, T.B., Hattersley, A.T.,
Hicks, A.A., Hindorff, L.A., Hingorani, A.D., Hofman, A., Homuth, G., Kees Hovingh, G., Humphries, S.E.,
Hunt, S.C., Hyppönen, E., Illig, T., Jacobs, K.B., Jarvelin, M.R., Jockel, K.H., Johansen, B., Jousilahti, P.,
Jukema, J.W., Jula, A.M., Kaprio, J., Kastelein, J.J., Keinanen-Kiukaanniemi, S.M., Kiemeney, L.A., Knekt,
page 108 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
P., Kooner, J.S., Kooperberg, C., Kovacs, P., Kraja, A.T., Kumari, M., Kuusisto, J., Lakka, T.A., Langenberg,
C., Le Marchand, L., Lehtimäki, T., Lyssenko, V., Männisto, S., Marette, A., Matise, T.C., McKenzie, C.A.,
McKnight, B., Moll, F.L., Morris, A.D., Morris, A.P., Murray, J.C., Nelis, M., Ohlsson, C., Oldehinkel, A.J.,
Ong, K.K., Madden, P.A., Pasterkamp, G., Peden, J.F., Peters, A., Postma, D.S., Pramstaller, P.P., Price,
J.F., Qi, L., Raitakari, O.T., Rankinen, T., Rao, D.C., Rice, T.K., Ridker, P.M., Rioux, J.D., Ritchie, M.D.,
Rudan, I., Salomaa, V., Samani, N.J., Saramies, J., Sarzynski, M.A., Schunkert, H., Schwarz, P.E., Sever,
P., Shuldiner, A.R., Sinisalo, J., Stolk, R.P., Strauch, K., Tönjes, A., Tregouet, D.A., Tremblay, A., Tremoli,
E., Virtamo, J., Vohl, M.C., Völker, U., Waeber, G., Willemsen, G., Witteman, J.C., Zillikens, M.C., Adair,
L.S., Amouyel, P., Asselbergs, F.W., Assimes, T.L., Bochud, M., Boehm, B.O., Boerwinkle, E., Bornstein,
S.R., Bottinger, E.P., Bouchard, C., Cauchi, S., Chambers, J.C., Chanock, S.J., Cooper, R.S., de Bakker,
P.I., Dedoussis, G., Ferrucci, L., Franks, P.W., Froguel, P., Groop, L.C., Haiman, C.A., Hamsten, A., Hui, J.,
Hunter, D.J., Hveem, K., Kaplan, R.C., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Martin, N.G., Marz, W.,
Melbye, M., Metspalu, A., Moebus, S., Munroe, P.B., Njølstad, I., Oostra, B.A., Palmer, C.N., Pedersen, N.L.,
Perola, M., Perusse, L., Peters, U., Power, C., Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo,
T.E., Saleheen, D., Sattar, N., Schadt, E.E., Schlessinger, D., Slagboom, P.E., Snieder, H., Spector, T.D.,
Thorsteinsdottir, U., Stumvoll, M., Tuomilehto, J., Uitterlinden, A.G., Uusitupa, M., van der Harst, P., Walker,
M., Wallaschofski, H., Wareham, N.J., Watkins, H., Weir, D.R., Wichmann, H.-E., Wilson, J.F., Zanen, P.,
Borecki, I.B., Deloukas, P., Fox, C.S., Heid, I.M., O'Connell, J.R., Strachan, D.P., Stefansson, K., van Duijn,
C.M., Abecasis, G.R., Franke, L., Frayling, T.M., McCarthy, M.I., Visscher, P.M., Scherag, A., Willer, C.J.,
Boehnke, M., Mohlke, K.L., Lindgren, C.M., Beckmann, J.S., Barroso, I., North, K.E., Ingelsson, E.,
Hirschhorn, J.N.°, Loos, R.J.°, Speliotes, E.K.°: Genetic studies of body mass index yield new insights for
obesity biology. Nature 518, 197-206 (2015)
Loss, G.°, Depner, M., Ulfman, L.H., van Neerven, R.J., Hose, A.J., Genuneit, J., Karvonen, A.M.,
Hyvärinen, A., Kaulek, V., Roduit, C., Weber, J., Lauener, R., Pfefferle, P.I., Pekkanen, J., Vaarala, O.,
Dalphin, J.C., Riedler, J., Braun-Fahrländer, C., von Mutius, E., Ege, M.J.: Consumption of unprocessed
cow's milk protects infants from common respiratory infections. J. Allergy Clin. Immunol. 135, 56-62 (2015)
Luzak, A., Flexeder, C., von Berg, A., Berdel, D., Klümper, C., Koletzko, S., Bauer, C.P., Heinrich, J.,
Nowak, D., Schulz, H.°: Relation of lung function and current inhalant allergen-specific immunoglobulin E
concentrations in adolescents (GINIplus cohort). Ann. Allerg. Asthma Immunol. 115, 183-190 (2015)
MacKenzie, B., Henneke, I., Hezel, S., Al Alam, D., El Agha, E., Chao, C.M., Quantius, J., Wilhelm, J.,
Jones, M., Goth, K., Li, X., Seeger, W., Königshoff, M., Herold, S., Rizvanov, A.A., Günther, A., Bellusci,
S.°: Attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise
murine lung repair. Am. J. Physiol. Lung Cell Mol. Physiol. 308, L1014-L1024 (2015)
Marcos, V., Zhou-Suckow, Z., Yildirim, A.Ö., Bohla, A., Hector, A., Vitkov, L., Krautgartner, W.D., Stoiber,
W., Griese, M., Eickelberg, O., Mall, M.A., Hartl, D.°: Free DNA in cystic fibrosis airway fluids correlates with
airflow obstruction. Mediators Inflamm. 2015:408935 (2015)
Meiners, S.°, Eickelberg, O., Königshoff, M.: Hallmarks of the ageing lung. Eur. Respir. J. 45, 807-827
(2015)
page 109 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
Meiners, S., Ballweg, K.: Proteostasis in pediatric pulmonary pathology. Mol. Cell. Pediatr. 1:11 (2014)
Möbs, C.#, Müller, J.#, Rudzio, A., Pickert, J., Blank, S., Jakob, T., Spillner, E., Pfützner, W.°: Decline of Ves
v 5-specific blocking capacity in wasp venom-allergic patients after stopping allergen immunotherapy. Allergy
70, 715-719 (2015)
Möller, W.°, Celik, G., Feng, S., Bartenstein, P., Meyer, G., Eickelberg, O., Schmid, O., Tatkov, S.: Nasal
high flow clears anatomical dead space in upper airway models. J. Appl. Physiol. 118, 1525-1532 (2015)
Mutze, K., Vierkotten, S., Milosevic, J., Eickelberg, O., Königshoff, M.°: Enolase 1 and protein disulfide
isomerase associated 3 regulate Wnt/β-catenin driven trans-differentiation of murine alveolar epithelial cells.
Dis. Model. Mech. 8, 877-890 (2015)
Obeidat, M., Hao, K., Bossé, Y., Nickle, D.C., Nie, Y., Postma, D.S., Laviolette, M., Sandford, A.J., Daley,
D.D., Hogg, J.C., Elliott, W.M., Fishbane, N., Timens, W., Hysi, P.G., Kaprio, J., Wilson, J.F., Hui, J., Rawal,
R., Schulz, H., Stubbe, B., Hayward, C., Polasek, O., Jarvelin, M.R., Zhao, J.H., Jarvis, D., Kähönen, M.,
Franceschini, N., North, K.E., Loth, D.W., Brusselle, G.G., Smith, A.V., Gudnason, V., Bartz, T.M., Wilk, J.B.,
O'Connor, G.T., Cassano, P.A., Tang, W., Wain, L.V., Artigas, M.S., Gharib, S.A., Strachan, D.P., Sin, D.D.,
Tobin, M.D., London, S.J., Hall, I.P., Paré, P.D.°: Molecular mechanisms underlying variations in lung
function: A systems genetics analysis. Lancet Resp. Med. 3, 782-795 (2015)
Oeder, S.#, Kanashova, T.#, Sippula, O.#, Sapcariu, S.C.#, Streibel, T.#, Arteaga-Salas, J.M.#, Passig, J.#,
Dilger, M., Paur, H.R., Schläger, C., Mülhopt, S., Diabaté, S., Weiss, C., Stengel, B., Rabe, R., Harndorf, H.,
Torvela, T., Jokiniemi, J.K., Hirvonen, M.R., Schmidt-Weber, C.B., Traidl-Hoffmann, C., BéruBé, K.A.,
Wlodarczyk, A.J., Prytherch, Z., Michalke, B., Krebs, T., Prévôt, A.S., Kelbg, M., Tiggesbäumker, J., Karg,
E.W., Jakobi, G., Scholtes, S., Schnelle-Kreis, J., Lintelmann, J., Matuschek, G., Sklorz, M., Klingbeil,
S., Orasche, J., Richthammer, P., Müller, L., Elsasser, M., Reda, A., Gröger, T.M., Weggler, B.A.,
Schwemer, T., Czech, H., Rüger, C.P., Abbaszade, G., Radischat, C., Hiller, K., Buters, J.T.M., Dittmar, G.,
Zimmermann, R.°: Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show
strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions. PLoS
ONE 10:e0126536 (2015)
Oeder, S.°, Alessandrini, F., Wirz, O.F., Braun, A., Wimmer, M., Frank, U., Hauser, M., Durner, J.,
Ferreira, F., Ernst, D., Mempel, M., Gilles, S., Buters, J.T.M., Behrendt, H., Traidl-Hoffmann, C.,
Schmidt-Weber, C.B., Akdis, M., Gutermuth, J.°: Pollen-derived non-allergenic substances enhance
Th2-induced IgE production in B cells. Allergy 70, 1450-1460 (2015)
Oehrle, B., Burgstaller, G., Irmler, M., Dehmel, S., Grün, J., Hwang, T., Krauss-Etschmann, S.,
Beckers, J., Meiners, S., Eickelberg, O.°: Validated prediction of pro-invasive growth factors using a
transcriptome-wide invasion signature derived from a complex 3D invasion assay. Sci. Rep. 5:12673 (2015)
page 110 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
Ohnmacht, C., Park, J.H., Cording, S., Wing, J.B., Atarashi, K., Obata, Y., Gaboriau-Routhiau, V., Marques,
R., Dulauroy, S., Fedoseeva, M., Busslinger, M., Cerf-Bensussan, N., Boneca, I.G., Voehringer, D., Hase,
+
K., Honda, K., Sakaguchi, S., Eberl, G.°: The microbiota regulates type 2 immunity through RORγt T cells.
Science 349, 989-993 (2015)
Ollert, M.°, Blank, S.°: Anaphylaxis to insect venom allergens: Role of molecular diagnostics. Curr. Allergy
Asthma Rep. 15:26 (2015)
Oteros, J.°, Garcia-Mozo, H., Alcázar, P., Belmonte, J., Bermejo, D., Boi, M., Cariñanos, P., Díaz de la
Guardia, C., Fernández-González, D., González-Minero, F., Gutiérrez-Bustillo, A.M., Moreno-Grau, S.,
Pérez-Badía, R., Rodríguez-Rajo, F.J., Ruíz-Valenzuela, L., Suárez-Pérez, J., Trigo, M.M.,
Domínguez-Vilches, E., Galan, C.: A new method for determining the sources of airborne particles. J.
Environ. Manage. 155, 212-218 (2015)
Oteros, J., Pusch, G., Weichenmeier, I., Heimann, U., Moller, R.S., Röseler, S., Traidl-Hoffmann, C.,
Schmidt-Weber, C.B., Buters, J.T.M.°: Automatic and online pollen monitoring. Int. Arch. Allergy Immunol.
167, 158-166 (2015)
Oteros, J.°, Garcia-Mozo, H., Botey, R., Mestre, A., Galan, C.: Variations in cereal crop phenology in Spain
over the last twenty-six years (1986-2012). Clim. Change 130, 545-558 (2015)
Pappa, I., St Pourcain, B., Benke, K., Cavadino, A., Hakulinen, C., Nivard, M.G., Nolte, I.M., Tiesler, C.M.,
Bakermans-Kranenburg, M.J., Davies, G.E., Evans, D.M., Geoffroy, M.C., Grallert, H., Groen-Blokhuis,
M.M., Hudziak, J.J., Kemp, J.P., Keltikangas-Järvinen, L., McMahon, G., Mileva-Seitz, V.R., Motazedi, E.,
Power, C., Raitakari, O.T., Ring, S.M., Rivadeneira, F., Rodriguez, A., Scheet, P.A., Seppälä, I., Snieder, H.,
Standl, M., Thiering, E., Timpson, N.J., Veenstra, R., Velders, F.P., Whitehouse, A.J., Smith, G.D.,
Heinrich, J., Hyppönen, E., Lehtimäki, T., Middeldorp, C.M., Oldehinkel, A.J., Pennell, C.E., Boomsma, D.I.,
Tiemeier, H.°: A genome-wide approach to children's aggressive behavior: The EAGLE consortium. Am. J.
Med. Genet. B, DOI: 10.1002/ajmg.b.32333 (2015)
page 111 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
Paternoster, L.°, Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D.P., Curtin, J.A., Bonnelykke,
K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A.C., Thyssen, J.P., den Dekker, H.T., Ferreira, M.A.,
Altmaier, E.M., Sleiman, P.M.A., Xiao, F.L., Gonzalez, J.R., Marenholz, I., Kalb, B., Pino-Yanes, M., Xu, C.,
Carstensen, L., Groen-Blokhuis, M.M., Venturini, C., Pennell, C.E., Barton, S.J., Levin, A.M., Curjuric, I.,
Bustamante, M., Kreiner-Moller, E., Lockett, G.A., Bacelis, J., Bunyavanich, S., Myers, R.A., Matanovic, A.,
Kumar, A., Tung, J.Y., Hirota, T., Kubo, M., McArdle, W.L., Henderson, A.J., Kemp, J.P., Zheng, J.H., Smith,
G.D., Rueschendorf, F., Bauerfeind, A., Lee-Kirsch, M.A., Arnold, A., Homuth, G., Schmidt, C.O., Mangold,
E., Cichon, S., Keil, T., Rodriguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Foelster-Holst, R.,
Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L.L., Grarup, N., de Jongste, J.C., Rivadeneira, F.,
Hofman, A., Jaddoe, V.W.V., Pasmans, S.G.M.A., Elbert, N.J., Uitterlinden, A.G., Marks, G.B., Thompson,
P.J., Matheson, M.C., Robertson, C.F., Ried, J.S., Li, J., Zuo, X.B., Zheng, X.D., Yin, X.Y., Sun, L.D.,
McAleer, M.A., O'Regan, G.M., Fahy, C.M.R., Campbell, L.E., Macek, M., Kurek, M., Hu, D., Eng, C.,
Postma, D.S., Feenstra, B., Geller, F., Hottenga, J.J., Middeldorp, C.M., Hysi, P., Bataille, V., Spector, T.,
Tiesler, C.M., Thiering, E., Pahukasahasram, B., Yang, J.J., Imboden, M., Huntsman, S., Vilor-Tejedor, N.,
Relton, C.L., Myhre, R., Nystad, W., Custovic, A., Weiss, S.T., Meyers, D.A., Soederhaell, C., Melén, E.,
Ober, C., Raby, B.A., Simpson, A., Jacobsson, B., Holloway, J.W., Bisgaard, H., Sunyer, J., Probst-Hensch,
N.M., Williams, L.K., Godfrey, K.M., Wang, C.A., Boomsma, D.I., Melbye, M., Koppelman, G.H., Jarvis, D.,
McLean, W.H.I., Irvine, A.D., Zhang, X.J., Hakonarson, H., Gieger, C., Burchard, E.G., Martin, N.G., Duijts,
L., Linneberg, A., Jarvelin, M.R., Nöthen, M.M., Lau, S., Huebner, N., Lee, Y., Tamari, M., Hinds, D.A.,
Glass, D., Brown, S.J., Heinrich, J., Evans, D.M., Weidinger, S., Australian Asthma Genetics Consortium
(AAGC), EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium: Multi-ancestry
genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic
dermatitis. Nat. Genet. 47, 1449-1456 (2015)
Pedata, P., Stöger, T.°, Zimmermann, R., Peters, A., Oberdörster, G., D'Anna, A.: "Are we forgetting the
smallest, sub 10 nm combustion generated particles?" Part. Fibre Toxicol. 12:34 (2015)
Peng, S., Liu, L., Zhang, X., Heinrich, J., Zhang, J., Schramm, K.-W., Huang, Q., Tian, M., Eqani, S.A.,
Shen, H.°: A nested case-control study indicating heavy metal residues in meconium associate with maternal
gestational diabetes mellitus risk. Environ. Health 14:19 (2015)
Poirier, J.G., Brennan, P.J., McKay, J.D., Spitz, M.R., Bickeböller, H., Risch, A., Liu, G., Le Marchand, L.,
Tworoger, S.S., McLaughlin, J.R., Rosenberger, A., Heinrich, J., Brüske, I., Muley, T.R., Henderson, B.,
Wilkens, L.R., Zong, X., Li, Y., Hao, K., Timens, W., Bossé, Y., Sin, D., Obeidat, M.A., Amos, C.I., Hung, R.°:
Informed genome-wide association analysis with family history as a secondary phenotype identifies novel
loci of lung cancer. Genet. Epidemiol. 39, 197-206 (2015)
page 112 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
Qi, Q.°, Downer, M.K., Kilpeläinen, T.O., Taal, H.R., Barton, S.J., Ntalla, I., Standl, M., Boraska, V., Huikari,
V., Kiefte-de Jong, J.C., Körner, A., Lakka, T.A., Liu, G., Magnusson, J., Okuda, M., Raitakari, O., Richmond,
R., Scott, R.A., Bailey, M.E., Scheuermann, K., Holloway, J.W., Inskip, H.M., Isasi, C.R., Mossavar-Rahmani,
Y., Jaddoe, V.W., Laitinen, J., Lindi, V., Melén, E., Pitsiladis, Y., Pitkänen, N., Snieder, H., Heinrich, J.,
Timpson, N.J., Wang, T., Yuji, H., Zeggini, E., Dedoussis, G.V., Kaplan, R.C., Wylie-Rosett, J., Loos, R.J.,
Hu, F.B., Qi, L.°: Dietary intake, FTO genetic variants and adiposity: A combined analysis of over 16,000
children and adolescents. Diabetes 64, 2467-2476 (2015)
Qian, D.C., Byun, J., Han, Y., Greene, C.S., Field, J.K., Hung, R.J., Brhane, Y., McLaughlin, J.R., Fehringer,
G., Landi, M.T., Rosenberger, A., Bickeböller, H., Malhotra, J., Risch, A., Heinrich, J., Hunter, D.J.,
Henderson, B.E., Haiman, C.A., Schumacher, F.R., Eeles, R.A., Easton, D.F., Seminara, D., Amos, C.I.°:
Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate
from genome-wide association studies and tissue-specific protein interactions. Hum. Mol. Genet. 24,
7406-7420 (2015)
Rädler, D., Schaub, B.°: Immune mechanisms and development of childhood asthma. Lancet Resp. Med. 2,
647-656 (2014)
Rosenberger, A.°, Friedrichs, S., Amos, C.I., Brennan, P., Fehringer, G., Heinrich, J., Hung, R.J., Muley,
T.R., Müller-Nurasyid, M., Risch, A., Bickeböller, H.: META-GSA: Combining findings from gene-set
analyses across several genome-wide association studies. PLoS ONE 10:e0140179 (2015)
Rosewich, M.°, Zissler, U.M., Kheiri, T., Voss, S., Eickmeier, O., Schulze, J., Herrmann, E., Dücker, R.P.,
Schubert, R., Zielen, S.: Airway inflammation in children and adolescents with bronchiolitis obliterans.
Cytokine 73, 156-162 (2015)
Sarker, R.S., John-Schuster, G., Bohla, A., Mutze, K., Burgstaller, G., Bedford, M.T., Königshoff, M.,
Eickelberg, O., Yildirim, A.Ö.°: CARM1 regulates alveolar epithelial senescence and elastase-induced
emphysema susceptibility. Am. J. Respir. Cell Mol. Biol. 53, 769-781 (2015)
Schamberger, A.C., Staab-Weijnitz, C.A., Mise-Racek, N., Eickelberg, O.°: Cigarette smoke alters
primary human bronchial epithelial cell differentiation at the air-liquid interface. Sci. Rep. 5:8163 (2015)
Schiller, H.°, Fernandez, I.E., Burgstaller, G., Schaab, C., Scheltema, R.A., Schwarzmayr, T., Strom,
T.M., Eickelberg, O.°, Mann, M.°: Time- and compartment-resolved proteome profiling of the extracellular
niche in lung injury and repair. Mol. Syst. Biol. 11:819 (2015)
Schloter, M.°, Kostric, M., Schöler, A., Treichel, N., Krauss-Etschmann, S., Berg, G.: Die Bedeutung des
humanen Mikrobioms für die menschliche Gesundheit. BIOspektrum 21, 39-40 (2015)
Schremser, K.°, Rogowski, W.H., Adler-Reichel, S., Tufman, A.L., Huber, R.M., Stollenwerk, B.:
Cost-effectiveness of an individualized first-line treatment strategy offering erlotinib based on EGFR mutation
testing in advanced lung adenocarcinoma patients in Germany. Pharmacoeconomics 33, 1215-1228 (2015)
page 113 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
Seher, T, Thiering, E., al Azemi, M., Heinrich, J., Schmidt-Weber, C.B., Kivlahan, C., Gutermuth, J.,
Fatemi, H.M.°: Is parental consanguinity associated with reduced ovarian reserve? Reprod. Biomed. Online
31, 427-433 (2015)
Sekula, P., Goek, O.N., Quaye, L., Barrios, C., Levey, A.S., Römisch-Margl, W., Menni, C., Yet, I., Gieger,
C., Inker, L.A., Adamski, J., Gronwald, W., Illig, T., Dettmer, K., Krumsiek, J., Oefner, P.J., Valdes, A.M.,
Meisinger, C., Coresh, J., Spector, T.D., Mohney, R.P., Suhre, K., Kastenmüller, G.°, Köttgen, A.°: A
metabolome-wide association study of kidney function and disease in the general population. J. Am. Soc.
Nephrol. 27, 1175-1188 (2016) [published online 2015]
Semren, N., Welk, V., Korfei, M., Keller, I.E., Fernandez, I.E., Adler, H., Günther, A., Eickelberg, O.,
Meiners, S.°: Regulation of 26S proteasome activity in pulmonary fibrosis. Am. J. Respir. Crit. Care Med.
192, 1089-1101 (2015)
Semren, N., Habel-Ungewitter, N.C., Fernandez, I.E., Königshoff, M., Eickelberg, O., Stöger, T.,
Meiners, S.°: Validation of the 2nd generation proteasome inhibitor oprozomib for local therapy of pulmonary
fibrosis. PLoS ONE 10:e0136188 (2015)
page 114 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
Shungin, D., Winkler, T.W., Croteau-Chonka, D.C., Ferreira, T., Locke, A.E., Mägi, R., Strawbridge, R.J.,
Pers, T.H., Fischer, K., Justice, A.E., Workalemahu, T., Wu, J.M., Buchkovich, M.L., Heard-Costa, N.L.,
Roman, T.S., Drong, A.W., Song, C., Gustafsson, S., Day, F.R., Esko, T., Fall, T., Kutalik, Z., Luan, J.,
Randall, J.C., Scherag, A., Vedantam, S., Wood, A.R., Chen, J., Fehrmann, R.S.N., Karjalainen, J., Kahali,
B., Liu, C.T., Schmidt, E.M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bragg-Gresham, J.L.,
Buyske, S., Demirkan, A., Ehret, G.B., Feitosa, M.F., Goel, A., Jackson, A.U., Johnson, T., Kleber, M.E.,
Kristiansson, K., Mangino, M., Mateo Leach, I., Medina-Gomez, C., Palmer, C.D., Pasko, D., Pechlivanis, S.,
Peters, M.J., Prokopenko, I., Stancáková, A., Ju Sung, Y., Tanaka, T., Teumer, A., van Vliet-Ostaptchouk,
J.V., Yengo, L., Zhang, W., Albrecht, E., Ärnlöv, J., Arscott, G.M., Bandinelli, S., Barrett, A., Bellis, C.,
Bennett, A.J., Berne, C., Blüher, M., Böhringer, S., Bonnet, F., Böttcher, Y., Bruinenberg, M., Carba, D.B.,
Caspersen, I.H., Clarke, R., Daw, E.W., Deelen, J., Deelman, E., Delgado, G., Doney, A.S., Eklund, N.,
Erdos, M.R., Estrada, K., Eury, E., Friedrich, N., Garcia, M.E., Giedraitis, V., Gigante, B., Go, A.S., Golay, A.,
Grallert, H., Grammer, T.B., Gräßler, J., Grewal, J., Groves, C.J., Haller, T., Hallmans, G., Hartman, C.A.,
Hassinen, M., Hayward, C., Heikkilä, K., Herzig, K.H., Helmer, Q., Hillege, H.L., Holmen, O.L., Hunt, S.C.,
Isaacs, A., Ittermann, T., James, A.L., Johansson, I., Juliusdottir, T., Kalafati, I.P., Kinnunen, L., Koenig, W.,
Kooner, I.K., Kratzer, W., Lamina, C., Leander, K., Lee, N.R., Lichtner, P., Lind, L., Lindstrom, J., Lobbens,
S., Lorentzon, M., Mach, F., Magnusson, P.K., Mahajan, A., McArdle, W.L., Menni, C., Merger, S., Mihailov,
E., Milani, L., Mills, R., Moayyeri, A., Monda, K.L., Mooijaart, S.P., Mühleisen, T.W., Mulas, A., Müller, G.,
Müller-Nurasyid, M., Nagaraja, R., Nalls, M.A., Narisu, N., Glorioso, N., Nolte, I.M., Olden, M., Rayner,
N.W., Renström, F., Ried, J.S., Robertson, N.R., Rose, L.M., Sanna, S., Scharnagl, H., Scholtens, S.,
Sennblad, B., Seufferlein, T., Sitlani, C.M., Smith, A.V., Stirrups, K., Stringham, H.M., Sundström, J., Swertz,
M.A., Swift, A.J., Syvanen, A.C., Tayo, B.O., Thorand, B., Thorleifsson, G., Tomaschitz, A., Troffa, C., van
Oort, F.V., Verweij, N., Vonk, J.M., Waite, L.L., Wennauer, R., Wilsgaard, T., Wojczynski, M.K., Wong, A.,
Zhang, Q., Hua Zhao, J., Brennan, E.P., Choi, M., Eriksson, P., Folkersen, L., Franco-Cereceda, A., Gharavi,
A.G., Hedman, A.K., Hivert, M.F., Huang, J., Kanoni, S., Karpe, F., Keildson, S., Kiryluk, K., Liang, L., Lifton,
R.P., Ma, B., McKnight, A.J., McPherson, R., Metspalu, A., Min, J.L., Moffatt, M.F., Montgomery, G.W.,
Murabito, J.M., Nicholson, G., Nyholt, D.R., Olsson, C., Perry, J.R., Reinmaa, E., Salem, R.M., Sandholm,
N., Schadt, E.E., Scott, R.A., Stolk, L., Vallejo, E.E., Westra, H.J., Zondervan, K.T., Amouyel, P., Arveiler, D.,
Bakker, S.J., Beilby, J., Bergman, R.N., Blangero, J., Brown, M.J., Burnier, M., Campbell, H., Chakravarti, A.,
Chines, P.S., Claudi-Boehm, S., Collins, F.S., Crawford, D.C., Danesh, J., de Faire, U., de Geus, E.J., Dörr,
M., Erbel, R., Eriksson, J.G., Farrall, M., Ferrannini, E., Ferrieres, J., Forouhi, N.G., Forrester, T., Franco,
O.H., Gansevoort, R.T., Gieger, C., Gudnason, V., Haiman, C.A., Harris, T.B., Hattersley, A.T., Heliövaara,
M., Hicks, A.A., Hingorani, A.D., Hoffmann, W., Hofman, A., Homuth, G., Humphries, S.E., Hyppönen, E.,
Illig, T., Jarvelin, M.R., Johansen, B., Jousilahti, P., Jula, A.M., Kaprio, J., Kee, F., Keinanen-Kiukaanniemi,
S.M., Kooner, J.S., Kooperberg, C., Kovacs, P., Kraja, A.T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Lakka,
T.A., Langenberg, C., Le Marchand, L., Lehtimäki, T., Lyssenko, V., Männisto, S., Marette, A., Matise, T.C.,
McKenzie, C.A., McKnight, B., Musk, A.W., Möhlenkamp, S., Morris, A.D., Nelis, M., Ohlsson, C., Oldehinkel,
A.J., Ong, K.K., Palmer, L.J., Penninx, B.W., Peters, A., Pramstaller, P.P., Raitakari, O.T., Rankinen, T.,
Rao, D.C., Rice, T.K., Ridker, P.M., Ritchie, M.D., Rudan, I., Salomaa, V., Samani, N.J., Saramies, J.,
Sarzynski, M.A., Schwarz, P.E., Shuldiner, A.R., Staessen, J.A., Steinthorsdottir, V., Stolk, R.P., Strauch,
K., Tönjes, A., Tremblay, A., Tremoli, E., Vohl, M.C., Völker, U., Vollenweider, P., Wilson, J.F., Witteman,
J.C., Adair, L.S., Bochud, M., Boehm, B.O., Bornstein, S.R., Bouchard, C., Cauchi, S., Caulfield, M.J.,
page 115 of 213
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
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Chambers, J.C., Chasman, D.I., Cooper, R.S., Dedoussis, G., Ferrucci, L., Froguel, P., Grabe, H.J.,
Hamsten, A., Hui, J., Hveem, K., Jockel, K.H., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Marz, W., Munroe,
P.B., Njølstad, I., Oostra, B.A., Palmer, C.N., Pedersen, N.L., Perola, M., Perusse, L., Peters, U., Power, C.,
Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo, T.E., Saleheen, D., Sinisalo, J., Slagboom, P.E.,
Snieder, H., Spector, T.D., Thorsteinsdottir, U., Stumvoll, M., Tuomilehto, J., Uitterlinden, A.G., Uusitupa, M.,
van der Harst, P., Veronesi, G., Walker, M., Wareham, N.J., Watkins, H., Wichmann, H.-E., Abecasis, G.R.,
Assimes, T.L., Berndt, S.I., Boehnke, M., Borecki, I.B., Deloukas, P., Franke, L., Frayling, T.M., Groop, L.C.,
Hunter, D.J., Kaplan, R.C., O'Connell, J.R., Qi, L., Schlessinger, D., Strachan, D.P., Stefansson, K., van
Duijn, C.M., Willer, C.J., Visscher, P.M., Yang, J., Hirschhorn, J.N., Zillikens, M.C., McCarthy, M.I., Speliotes,
E.K., North, K.E., Fox, C.S., Barroso, I., Franks, P.W., Ingelsson, E., Heid, I.M., Loos, R.J., Cupples, L.A.,
Morris, A.P., Lindgren, C.M.°, Mohlke, K.L.°: New genetic loci link adipose and insulin biology to body fat
distribution. Nature 518, 187-196 (2015)
Smith, M., Berdel, D., Nowak, D., Heinrich, J., Schulz, H.°: Sport engagement by accelerometry under field
conditions in German adolescents: Results from GINIPlus. PLoS ONE 10:e0135630 (2015)
Sotoodehnejadnematalahi, F., Staples, K.J., Chrysanthou, E., Pearson, H., Ziegler-Heitbrock, L., Burke,
B.°: Mechanisms of hypoxic up-regulation of versican gene expression in macrophages. PLoS ONE
10:e0125799 (2015)
Staab-Weijnitz, C.A., Fernandez, I.E., Knüppel, L., Maul, J., Heinzelmann, K., Juan-Guardela, B.M.,
Hennen, E., Preissler, G., Winter, H., Neurohr, C., Hatz, R.A., Lindner, M., Behr, J., Kaminski, N.,
Eickelberg, O.°: FK506-binding protein 10 is a potential novel drug target for idiopathic pulmonary fibrosis.
Am. J. Respir. Crit. Care Med. 192, 455-467 (2015)
Standl, M.°, Demmelmair, H., Koletzko, B., Heinrich, J.: Cord blood n-3 LC-PUFA is associated with
adiponectin concentrations at 10 years of age. Prostaglandins Leukot. Essent. Fatty Acids 96, 51-55 (2015)
Stuart, P.E.#, Nair, R.P.#, Tsoi, L.C.#, Tejasvi, T., Das, S., Kang, H.M., Ellinghaus, E., Chandran, V.,
Callis-Duffin, K., Ike, R.W., Li, Y., Wen, X., Enerbäck, C., Gudjonsson, J.E., Kõks, S., Kingo, K., Esko, T.,
Mrowietz, U., Reis, A., Wichmann, H.-E., Gieger, C., Hoffmann, P., Nöthen, M.M., Winkelmann, J., Kunz,
M., Moreta, E.G., Mease, P.J., Ritchlin, C.T., Bowcock, A.M., Krueger, G.G., Lim, H.W., Weidinger, S.,
Weichenthal, M., Voorhees, J.J., Rahman, P., Gregersen, P.K., Franke, A., Gladman, D.D., Abecasis, G.R.,
Elder, J.T.°: Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals
differences in their genetic architecture. Am. J. Hum. Genet. 97, 816-836 (2015)
Sun, N., Fernandez, I.E., Wei, M., Wu, Y., Aichler, M., Eickelberg, O.°, Walch, A.K.°: Pharmacokinetic
and pharmacometabolomic study of pirfenidone in normal mouse tissues using high mass resolution
MALDI-FTICR-mass spectrometry imaging. Histochem. Cell Biol. 145, 201-211 (2016) [published online
2015]
page 116 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
#
#
Swerdlow, D.I. , Preiss, D. , Kuchenbaecker, K.B., Holmes, M.V., Engmann, J.E.L., Shah, T., Sofat, R.,
Stender, S., Johnson, P.C.D., Scott, R.A., Leusink, M., Verweij, N., Sharp, S.J., Guo, Y., Giambartolomei, C.,
Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J., Howard, P., Cooper, J.A., Drenos, F., Li, Y.R., Lowe,
G., Gallacher, J., Stewart, M.C.W., Tzoulaki, I., Buxbaum, S.G., Daphne, L.v.d.A., Forouhi, N.G.,
Onland-Moret, N.C., van der Schouw, Y.T., Schnabel, R.B., Hubácek, J.A., Kubínová, R., Baceviciene, M.,
Tamosiunas, A., Pajak, A., Topor-Madry, R., Stepaniak, U., Malyutina, S.A., Baldassarre, D., Sennblad, B.,
Tremoli, E., de Faire, U., Veglia, F., Ford, I., Jukema, J.W., Westendorp, R.G.J., de Borst, G.J., De Jong,
P.A., Algra, A., Spiering, W., Maitland-van der Zee, A.H., Klungel, O.H., de Boer, A., Doevendans, P.A.,
Eaton, C.B., Robinson, J.G., Duggan, D., Kjekshus, J., Downs, J.R., Gotto, A.M., Keech, A.C., Marchioli, R.,
Tognoni, G., Sever, P.S., Poulter, N.R., Waters, D.D., Pedersen, T.R., Amarenco, P., Nakamura, H.,
McMurray, J.J.V., Lewsey, J.D., Chasman, D.I., Ridker, P.M., Maggioni, A.P., Tavazzi, L., Ray, K.K.,
Seshasai, S.R.K., Manson, J.E., Price, J.F., Whincup, P.H., Morris, R.W., Lawlor, D.A., Smith, G.D.,
Ben-Shlomo, Y., Schreiner, P.J., Fornage, M., Siscovick, D.S., Cushman, M., Kumari, M., Wareham, N.J.,
Verschuren, W.M.M., Redline, S., Patel, S.R., Whittaker, J.C., Hamsten, A., Delaney, J.A., Dale, C.E.,
Gaunt, T.R., Wong, A., Kuh, D., Hardy, R., Kathiresan, S., Castillo, B.A., van der Harst, P., Brunner, E.J.,
Tybjaerg-Hansen, A., Marmot, M.G., Krauss, R.M., Tsai, M., Coresh, J., Hoogeveen, R.C., Psaty, B.M.,
Lange, L.A., Hakonarson, H., Dudbridge, F., Humphries, S.E., Talmud, P.J., Kivimaeki, M., Timpson, N.J.,
Langenberg, C., Asselbergs, F.W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J.G., Reiner, A.P., Keating,
B.J., Hingorani, A.D.°, Sattar, N.°, DIAGRAM Consortium (Grallert, H., Gieger, C., Klopp, N., Illig, T.,
Müller-Nurasyid, M., Peters, A.), MAGIC Consortium (Meisinger, C., Thorand, B., Wichmann, H.-E.),
InterAct Consortium: HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence
from genetic analysis and randomised trials. Lancet 385, 351-361 (2015)
Taeger, D., Pesch, B., Kendzia, B., Behrens, T., Jockel, K.H., Dahmann, D., Siemiatycki, J., Kromhout, H.,
Vermeulen, R., Peters, S., Olsson, A., Brüske, I., Wichmann, H.-E., Stücker, I., Guida, F., Tardón, A.,
Merletti, F., Mirabelli, D., Richiardi, L., Pohlabeln, H., Ahrens, W., Landi, M.T., Caporaso, N., Pesatori, A.C.,
Mukeriya, A., Szeszenia-Dabrowska, N., Lissowska, J., Gustavsson, P., Field, J., Marcus, M.W., Fabianova,
E., 't Mannetje, A., Pearce, N., Rudnai, P., Bencko, V., Janout, V., Dumitru, R.S., Foretova, L., Forastiere, F.,
McLaughlin, J., Demers, P.D., Bueno-de-Mesquita, B., Schüz, J., Straif, K., Brüning, T.°: Lung cancer among
coal miners, ore miners and quarrymen: Smoking-adjusted risk estimates from the synergy pooled analysis
of case-control studies. Scand. J. Work Environ. Health 41, 467-477 (2015)
Thannickal, V.J., Murthy, M., Balch, W.E., Chandel, N.S., Meiners, S., Eickelberg, O., Selman, M., Pardo,
A., White, E.S., Levy, B.D., Busse, P.J., Tuder, R.M., Antony, V.B., Sznajder, J.I., Budinger, G.R.°: Blue
journal conference : Aging and susceptibility to lung disease. Am. J. Respir. Crit. Care Med. 191, 261-269
(2015)
Thiering, E.°, Brüske, I., Kratzsch, J., Hofbauer, L.C., Berdel, D., von Berg, A., Lehmann, I., Hoffmann, B.,
Bauer, C.P., Koletzko, S., Heinrich, J.: Associations between serum 25-hydroxyvitamin D and bone turnover
markers in a population based sample of German children. Sci. Rep. 5:18138 (2015)
Thiering, E.°, Heinrich, J.: Epidemiology of air pollution and diabetes. Trends Endocrinol. Metab. 26,
384-394 (2015)
page 117 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
#
#
Tian, F. , Clift, M.J. , Casey, A., del Pino, P., Pelaz, B., Conde, J., Byrne, H.J., Rothen-Rutishauser, B.,
Estrada, G., de la Fuente, J.M., Stöger, T.°: Investigating the role of shape on the biological impact of gold
nanoparticles in vitro. Nanomed. 10, 2643-2657 (2015)
Tiesler, C.M., Thiering, E., Tischer, C.G., Lehmann, I., Schaaf, B., von Berg, A., Heinrich, J.°: Exposure to
visible mould or dampness at home and sleep problems in children: Results from the LISAplus study.
Environ. Res. 137, 357-363 (2015)
Tischer, C.G.°, Zock, J.P., Valkonen, M., Doekes, G., Guerra, S., Heederik, D., Jarvis, D., Norbäck, D.,
Olivieri, M., Sunyer, J., Svanes, C., Täubel, M., Thiering, E., Verlato, G., Hyvärinen, A., Heinrich, J.:
Predictors of microbial agents in dust and respiratory health in the Ecrhs. BMC Pulm. Med. 15:48 (2015)
Tischer, C.G.°, Standl, M., Lehmann, I., Schaaf, B., von Berg, A., Heinrich, J.: Sleeping on animal fur is
related to asthma outcomes in later childhood. Eur. Respir. J. 46, 107-114 (2015)
Tsai, M.Y.°, Hoek, G., Eeftens, M., de Hoogh, K., Beelen, R., Beregszaszi, T., Cesaroni, G., Cirach, M.,
Cyrys, J., de Nazelle, A., de Vocht, F., Ducret-Stich, R., Eriksen, K., Galassi, C., Grazuleviciene, R.,
Gražulevicius, T., Grivas, G., Gryparis, A., Heinrich, J., Hoffmann, B., Iakovides, M., Keuken, M., Krämer,
U., Künzli, N., Lanki, T., Madsen, C., Meliefste, K., Merritt, A.S., Mölter, A., Mosler, G., Nieuwenhuijsen, M.J.,
Pershagen, G., Phuleria, H., Quass, U., Ranzi, A., Schaffner, E., Sokhi, R.S., Stempfelet, M., Stephanou, E.,
Sugiri, D., Taimisto, P., Tewis, M., Udvardy, O., Wang, M., Brunekreef, B.: Spatial variation of PM elemental
composition between and within 20 European study areas - results of the ESCAPE project. Environ. Int. 84,
181-192 (2015)
Uhl, F., Vierkotten, S., Wagner, D., Burgstaller, G., Costa, R., Koch, I., Lindner, M., Meiners, S.,
Eickelberg, O., Königshoff, M.°: Preclinical validation and imaging of Wnt-induced repair in human 3D lung
tissue cultures. Eur. Respir. J. 46, 1150-1166 (2015)
van Dillen, T.°, Dekkers, F., Bijwaard, H., Brüske, I., Wichmann, H.-E., Kreuzer, M., Grosche, B.: Modeling
lung carcinogenesis in radon-exposed miner cohorts: Accounting for missing information on smoking. Risk
Anal., DOI: 10.1111/risa.12472 (2015)
van Rijt, S.H.°, Bölükbas, D.A., Argyo, C., Datz, S., Lindner, M., Eickelberg, O., Königshoff, M., Bein, T.,
Meiners, S.: Protease-mediated release of chemotherapeutics from mesoporous silica nanoparticles to ex
vivo human and mouse lung tumors. ACS Nano 9, 2377-2389 (2015)
Vock, C., Yildirim, A.Ö., Wagner, C., Schlick, S., Lunding, L.P., Lee, C.G., Elias, J.A., Fehrenbach, H.,
Wegmann, M.°: Distal airways are protected from goblet cell metaplasia by diminished expression of IL-13
signaling components. Clin. Exp. Allergy 45, 1447-1458 (2015)
Volaklis, K.A.°, Halle, M., Koenig, W., Oberhoffer, R., Grill, E., Peters, A., Strasser, B., Heier, M., Emeny,
R.T., Schulz, H., Ladwig, K.-H., Meisinger, C., Thorand, B.: Association between muscular strength and
inflammatory markers among elderly persons with cardiac disease: Results from the KORA-Age study. Clin.
Res. Cardiol. 104, 982-989 (2015)
page 118 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
von Berg, A.°, Filipiak-Pittroff, B., Schulz, H., Hoffmann, U., Link, E., Sußmann, M., Schnappinger, M.,
Brüske, I., Standl, M., Krämer, U., Hoffmann, B., Heinrich, J., Bauer, C.P., Koletzko, S., Berdel, D.,
GINIplus Study Group: Allergic manifestation 15 years after early intervention with hydrolyzed formulas - the
GINI study. Allergy 71, 210-219 (2016) [published online 2015]
Wain, L.V.#, Shrine, N.#, Miller, S., Jackson, V.E., Ntalla, I., Artigas, M.S., Billington, C.K., Kheirallah, A.K.,
Allen, R.P., Cook, J.P., Probert, K., Obeidat, M., Bossé, Y., Hao, K., Postma, D.S., Paré, P.D., Ramasamy,
A., Mägi, R., Mihailov, E., Reinmaa, E., Melén, E., O'Connell, J., Frangou, E., Delaneau, O., UK Brain
Expression Consortium (Lamina, C., Rawal, R., Wichmann, H.-E.), Freeman, C., Petkova, D., McCarthy,
M., Sayers, I., Deloukas, P., Hubbard, R., Pavord, I.D., Hansell, A.L., Thomson, N.C., Zeggini, E., Morris,
A.P., Marchini, J., Strachan, D.P., Tobin, M.D.°, Hall, I.P.: Novel insights into the genetics of smoking
behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): A genetic association
study in UK Biobank. Lancet Resp. Med. 3, 769-781 (2015)
#
#
Wimmer, M. , Alessandrini, F. °, Gilles, S., Frank, U., Oeder, S., Hauser, M., Ring, J., Ferreira, F., Ernst,
D., Winkler, J.B., Schmitt-Kopplin, P., Ohnmacht, C., Behrendt, H., Schmidt-Weber, C.B.,
Traidl-Hoffmann, C., Gutermuth, J.: Pollen-derived adenosine is a necessary co-factor for ragweed allergy.
Allergy 70, 944-954 (2015)
Wolf, K.°, Schneider, A.E., Breitner, S., Meisinger, C., Heier, M., Cyrys, J., Kuch, B., von Scheidt, W.,
Peters, A., KORA Study Group (Gieger, C., Grallert, H., Heinrich, J., Holle, R., Leidl, R., Strauch, K.):
Associations between short-term exposure to particulate matter and ultrafine particles and myocardial
infarction in Augsburg, Germany. Int. J. Hyg. Environ. Health 218, 535-542 (2015)
Yaroshenko, A., Hellbach, K., Yildirim, A.Ö., Conlon, T.M., Fernandez, I.E., Bech, M., Velroyen, A., Meinel,
F.G., Auweter, S., Reiser, M., Eickelberg, O., Pfeiffer, F.: Improved In vivo assessment of pulmonary fibrosis
in mice using X-ray dark-feld radiography. Sci. Rep. 5:17492 (2015)
Yin, R., Liu, X., Bi, Y., Xie, G., Zhang, P., Meng, X., Ai, L., Xu, R., Sun, Y., Stöger, T., Ding, Z.°: Expression
of raf kinase inhibitor protein is down regulated in response to newcastle disease virus infection to promote
viral replication. J. Gen. Virol. 96, 2579-2586 (2015)
Zawada, A.M., Fell, L.H., Untersteller, K., Seiler, S., Rogacev, K.S., Fliser, D., Ziegler-Heitbrock, L., Heine,
G.H.: Comparison of two different strategies for human monocyte subsets gating within the large-scale
prospective CARE FOR HOMe Study. Cytometry A 87, 750-758 (2015)
page 119 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Chronic Diseases of the Lung and Allergies
Zhang, C., Doherty, J.A., Burgess, S.L., Hung, R.J., Lindström, S., Kraft, P., Gong, J., Amos, C.I., Sellers,
T.A., Monteiro, A.N., Chenevix-Trench, G., Bickeböller, H., Risch, A., Brennan, P., Mckay, J., Houlston, R.,
Landi, M.T., Timofeeva, M., Wang, Y., Heinrich, J., Kote-Jarai, Z., Eeles, R.A., Muir, K., Wiklund, F.,
Grönberg, H., Berndt, S.I., Chanock, S.J., Schumacher, F., Haiman, C.A., Henderson, B.E., Amin Al Olama,
A., Andrulis, I.L., Hopper, J.L., Chang-Claude, J., John, E.M., Malone, K.E., Gammon, M.D., Ursin, G.,
Whittemore, A.S., Hunter, D.J., Gruber, S.B., Knight, J.A., Hou, L., Le Marchand, L., Newcomb, P.A.,
Hudson, T.J., Chan, A.T., Li, L., Woods, M.O., Ahsan, H., Pierce, B.L.°: Genetic determinants of telomere
length and risk of common cancers: A Mendelian randomization study. Hum. Mol. Genet. 24, 5356-5366
(2015)
Zhao, F., El-Kelish, A., Durner, J., Lindermayr, C., Winkler, J.B., Rueff, F., Behrendt, H., Traidl-Hoffmann,
C., Holzinger, A., Kofler, W., Braun, P., von Toerne, C., Hauck, S.M., Ernst, D., Frank, U.°: Common
ragweed (Ambrosia artemisiifolia L.): Allergenicity and molecular characterisation of pollen after plant
exposure to elevated NO2. Plant Cell Environ. 39, 147-164 (2016) [published online 2015]
Ziegler-Heitbrock, L.°: Blood monocytes and their subsets: Established features and open questions. Front.
Immunol. 6:423 (2015)
Zissler, U.M., Chaker, A.M., Effner, R., Ulrich, M., Guerth, F., Piontek, G., Dietz, K., Regn, M., Knapp, B.,
Theis, F.J., Heine, H., Suttner, K., Schmidt-Weber, C.B.°: Interleukin-4 and interferon-γ orchestrate an
epithelial polarization in the airways. Mucosal Immunol., DOI: 10.1038/mi.2015.110 (2015)
page 120 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Abend, M.°, Azizova, T.V., Müller, K., Dörr, H., Doucha-Senf, S., Kreppel, H., Rusinova, G., Glazkova, I.,
Vyazovskaya, N., Unger, K., Braselmann, H., Meineke, V.: Association of radiation-induced genes with
noncancer chronic diseases in Mayak workers occupationally exposed to prolonged radiation. Radiat. Res.
183, 249-261 (2015)
Aerts, A.M., Impens, N.R.E.N., Baatout, S.°, Benotmane, M.A., Camps, J., Dabin, J.M., Derradji, H.,
Grosche, B., Horemans, N., Jourdain, J.R., Moreels, M., Perko, T., Quintens, R., Repussard, J., Rühm, W.,
Schneider, T., Struelens, L., Hardeman, F.: Joint research towards a better radiation protection : Highlights of
the fifth MELODI workshop. J. Radiol. Prot. 34, 931-956 (2014)
Aichler, M., Walch, A.K.°: MALDI Imaging mass spectrometry: Current frontiers and perspectives in
pathology research and practice. Lab. Invest. 95, 422-431 (2015)
Aichler, M., Huber, K., Schilling, F., Lohöfer, F., Kosanke, K., Meier, R., Rummeny, E.J., Walch, A.K.°,
Wildgruber, M.: Spatially resolved quantification of Gadolinium(III)-based magnetic resonance agents in
tissue by MALDI imaging mass spectrometry after in vivo MRI. Angew. Chem.-Int. Edit. 54, 4279-4283
(2015)
Alloni, D.°, Baiocco, G., Babini, G., Friedland, W., Kundrát, P., Mariotti, L., Ottolenghi, A.: Energy
dependence of the complexity of DNA damage induced by carbon ions. Radiat. Prot. Dosim. 166, 86-90
(2015)
Almstätter, I., Mykhaylyk, O., Settles, M., Altomonte, J., Aichler, M., Walch, A.K., Rummeny, E.J., Ebert, O.,
Plank, C., Braren, R.°: Characterization of magnetic viral complexes for targeted delivery in oncology.
Theranostics 5, 667-685 (2015)
Alsadeq, A., Strube, S., Krause, S., Carlet, M., Jeremias, I., Vokuhl, C., Loges, S., Aguirre-Ghiso, J.A.,
Trauzold, A., Cario, G., Stanulla, M., Schrappe, M., Schewe, D.M.°: Effects of p38α/β inhibition on Acute
Lymphoblastic Leukemia (ALL) proliferation and survival in vivo. Leukemia 29, 2307-2316 (2015)
Alvarez Palomo, A.B., McLenachan, S., Chen, F.K., da Cruz, L., Dilley, R.J., Requena, J., Lucas, M., Lucas,
A., Drukker, M., Edel, M.J.°: Prospects for clinical use of reprogrammed cells for autologous treatment of
macular degeneration. Fibrogenesis Tissue Repair 8:9 (2015)
Ameres, S., Liang, X., Wiesner, M., Mautner, J., Moosmann, A.°: A diverse repertoire of CD4 T cells
targets the immediate-early 1 protein of human cytomegalovirus. Front. Immunol. 6:598 (2015)
Amort, M.#, Nachbauer, B.#, Tuzlak, S., Kieser, A., Schepers, A., Villunger, A., Polacek, N.°: Expression of
the vault RNA protects cells from undergoing apoptosis. Nat. Commun. 6:7030 (2015)
Anastasov, N.°, Höfig, I., Radulovic, V., Strobel, S., Salomon, M., Lichtenberg, J., Rothenaigner, I.,
Hadian, K., Kelm, J.M., Thirion, C., Atkinson, M.J.: A 3D-microtissue-based phenotypic screening of
radiation resistant tumor cells with synchronized chemotherapeutic treatment. BMC Cancer 15:466 (2015)
page 121 of 213
31.12.2015
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#
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° corresponding authors
HMGU authors are given in bold letters
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#
#
Andjeli, S. , Lumi, X. , Yan, X., Graw, J., Moe, M.C., Facskó, A., Hawlina, M., Petrovski, G.°:
Characterization of ex vivo cultured neuronal- and glial- like cells from human idiopathic epiretinal
membranes. BMC Ophthalmol. 14:165 (2014)
Andjelić, S., Drašlar, K., Lumi, X., Yan, X., Graw, J., Facskó, A., Hawlina, M., Petrovski, G.°: Morphological
and proliferative studies on ex vivo cultured human anterior lens epithelial cells - relevance to capsular
opacification. Acta Ophthalmol. 93, e499–e506 (2015)
Azimzadeh, O.°, Sievert, W., Sarioglu, H., Merl-Pham, J., Yentrapalli, R., Bakshi, M.V., Janik, D.,
Ueffing, M., Atkinson, M.J., Multhoff, G., Tapio, S.: Integrative proteomics and targeted transcriptomics
analyses in cardiac endothelial cells unravel mechanisms of long-term radiation-induced vascular
dysfunction. J. Proteome Res. 14, 1203-1219 (2015)
Azimzadeh, O., Atkinson, M.J., Tapio, S.°: Qualitative and quantitative proteomic analysis of
Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Methods Mol. Biol. 1295, 109-115 (2015)
Babini, G.°, Bellinzona, V.E., Morini, J., Baiocco, G., Mariotti, L., Unger, K., Ottolenghi, A.: Mechanisms of
the induction of apoptosis mediated by radiation-induced cytokine release. Radiat. Prot. Dosim. 166,
165-169 (2015)
Baptista, M.°, Figueira, C., Teles, P., Cardoso, G., Zankl, M., Vaz, P.: Assessment of the occupational
exposure in real time during interventional cardiology procedures. Radiat. Prot. Dosim. 165, 304-309 (2015)
Barbosa, J.S., Sanchez-Gonzalez, R., di Giaimo, R., Baumgart, E.V., Theis, F.J., Götz, M., Ninkovic,
J.°: Live imaging of adult neural stem cell behavior in the intact and injured zebrafish brain. Science 348,
789-793 (2015)
Barjaktarovic, Z., Kempf, S.J., Sriharshan, A., Merl-Pham, J., Atkinson, M.J., Tapio, S.°: Ionizing
radiation induces immediate protein acetylation changes in human cardiac microvascular endothelial cells. J.
Radiat. Res. 56, 623-632 (2015)
Barrett, H.H.°, Myers, K.J., Hoeschen, C., Kupinski, M.A., Little, M.P.: Task-based measures of image
quality and their relation to radiation dose and patient risk. Phys. Med. Biol. 60, R1-R75 (2015)
Bauer, C., Gobel, K., Nagaraj, N., Colantuoni, C., Wang, M., Müller, U., Kremmer, E., Rottach, A.,
Leonhardt, H.°: Phosphorylation of TET proteins is regulated via O-GlcNAcylation by the glycosyltransferase
OGT. J. Biol. Chem. 290, 4801-4812 (2015)
Bauer, C.°, Hees, C., Sterzik, A., Bauernfeind, F., Mak'Anyengo, R., Duewell, P., Lehr, H.A., Nößner, E.,
Wank, R., Trauzold, A., Endres, S., Dauer, M., Schnurr, M.: Proapoptotic and antiapoptotic proteins of the
Bcl-2 family regulate sensitivity of pancreatic cancer cells toward gemcitabine and T-cell-mediated
cytotoxicity. J. Immunother. 38, 116-126 (2015)
page 122 of 213
31.12.2015
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#
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° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Bauer, L., Takacs, A., Slotta-Huspenina, J., Langer, R., Becker, K., Novotny, A., Ott, K., Walch, A.K.,
Hapfelmeier, A., Keller, G.°: Clinical significance of NOTCH1 and NOTCH2 expression in gastric carcinomas:
An immunohistochemical study. Front. Oncol. 5:94 (2015)
Becker, L.#, Kling, E.#, Schiller, E., Zeh, R., Schrewe, A., Hölter, S.M., Mossbrugger, I., Calzada-Wack,
J., Strecker, V., Wittig, I., Dumitru, I., Wenz, T., Bender, A., Aichler, M., Janik, D., Neff, F., Walch, A.K.,
Quintanilla-Fend, L., Floß, T., Bekeredjian, R., Gailus-Durner, V., Fuchs, H., Wurst, W., Meitinger, T.,
Prokisch, H., Hrabě de Angelis, M., Klopstock, T.°: MTO1-deficient mouse model mirrors the human
phenotype showing complex I defect and cardiomyopathy. PLoS ONE 9:e114918 (2014)
#
#
#
Becker, P.D. , Nörder, M. , Weissmann, S. , Ljapoci, R., Erfle, V., Drexler, I., Guzman, C.A.°: Gene
expression driven by a strong viral promoter in MVA increases vaccination efficiency by enhancing antibody
responses and unmasking CD8⁺ T cell epitopes. Vaccines 2, 581-600 (2015)
Beckers, A.#°, Lodish, M.#, Giampaolo, T., Rostomyan, L., Lee, M.S., Faucz, F.R., Yuan, B., Choong, C.,
Caberg, J.H., Verrua, E., Naves, L.A., Cheetham, T., Young, J., Lysy, P., Petrossians, P., Cotterill, A., Shah,
N., Metzger, D., Castermans, E., Ambrosio, M.R., Villa, C., Strebkova, N., Mazerkina, N., Gaillard, S.,
Barcelos Barra, G., Casulari, L.A., Neggers, S., Salvatori, R., Jaffrain-Rea, M.L., Zacharin, M., Lecumberri
Santamaria, B., Zacharieva, S., Lim, E.M., Mantovani, G., Zatelli, M.C., Collins, M.T., Bonneville, J.F.,
Quezado, M.M., Chittiboina, P., Oldfield, E., Bours, V., Liu, P., de Herder, W.W., Pellegata, N.S., Lupski,
J.R., Daly, A.F., Stratakis, C.A.: X-Linked Acrogigantism (X-LAG) syndrome: Clinical profile and therapeutic
responses. Endocr.-Relat. Cancer 22, 353-367 (2015)
Beer, A.J.°, Pelisek, J., Heider, P., Saraste, A., Reeps, C., Metz, S., Seidl, S., Kessler, H., Wester, H.-J.,
Eckstein, H.H., Schwaiger, M.: PET/CT imaging of integrin αvβ3 expression in human carotid
atherosclerosis. JACC-Cardiovasc. Imag. 7, 178-187 (2014)
Belting, L., Hömberg, N., Przewoznik, M., Brenner, C., Riedel, T., Flatley, A., Polic, B., Busch, D.H.,
Röcken, M., Mocikat, R.°: Critical role of the NKG2D receptor for NK cell-mediated control and immune
escape of B-cell lymphoma. Eur. J. Immunol. 45, 2593-2601 (2015)
Bergami, M.°, Masserdotti, G., Temprana, S.G., Motori, E., Eriksson, T.M., Göbel, J., Yang, S.M.,
Conzelmann, K.K., Schinder, A.F., Götz, M., Berninger, B.: A critical period for experience-dependent
remodeling of adult-born neuron connectivity. Neuron 85, 710-717 (2015)
Bergs, J.W., Wacker, M.G., Hehlgans, S., Piiper, A., Multhoff, G., Rödel, C., Rödel, F.°: The role of recent
nanotechnology in enhancing the efficacy of radiation therapy. Biochim. Biophys. Acta-Rev. Cancer 1856,
130-143 (2015)
Bernauer, F.°, Hürkamp, K., Rühm, W., Tschiersch, J.: On the consistency of 2-D video disdrometers in
measuring microphysical parameters of solid precipitation. Atmos. Meas. Tech. 8, 3251-3261 (2015)
Berscheminski, J., Brun, J., Speiseder, T., Wimmer, P., Ip, W.H., Terzic, M., Dobner, T.°, Schreiner, S.°:
Sp100A is a tumor suppressor that activates p53-dependent transcription and counteracts
E1A/E1B-55K-mediated transformation. Oncogene, DOI: 10.1038/onc.2015.378 (2015)
page 123 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Bi, Z., Merl-Pham, J., Uehlein, N., Zimmer, I., Mühlhans, S., Aichler, M., Walch, A.K., Kaldenhoff, R.,
Palme, K., Schnitzler, J.-P., Block, K.°: RNAi-mediated downregulation of poplar Plasma membrane
Intrinsic Proteins (PIPs) changes plasma membrane proteome composition and affects leaf physiology. J.
Proteomics 128, 321-332 (2015)
Bolch, W.E.°, Dietze, G., Petoussi-Henß, N., Zankl, M.: Dosimetric models of the eye and lens of the eye
and their use in assessing dose coefficients for ocular exposures. Ann. ICRP 44, 91-111 (2015)
Bonaccorsi-Riani, E., Pennycuick, A., Londoño, M.C., Lozano, J.J., Benítez, C., Sawitzki, B.,
Martínez-Picola, M., Bohne, F., Martínez-Llordella, M., Miquel, R., Rimola, A., Sánchez-Fueyo, A.°:
Molecular characterization of acute cellular rejection occurring during intentional immunosuppression
withdrawal in liver transplantation. Am. J. Transplant. 16, 484-496 (2016) [published online 2015]
Bönisch, C., Irmler, M., Brachthäuser, L., Neff, F., Bamberger, M.T., Marschall, S., Hrabě de Angelis,
M., Beckers, J.: Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as
observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring. Mamm. Genome
27, 17-28 (2015)
Böttger, A., Islam, M.S., Chowdhury, R., Schofield, C.J., Wolf, A.°: The oxygenase Jmjd6-a case study in
conflicting assignments. Biochem. J. 468, 191-202 (2015)
Boutaffala, L.#, Bertrand, M.J.#, Remouchamps, C.#, Seleznik, G.M., Reisinger, F., Janas, M., Bénézech, C.,
Fernandes, M.T., Marchetti, S., Mair, F., Ganeff, C., Hupalowska, A., Ricci, J.E., Becher, B., Piette, J.,
Knolle, P., Caamano, J., Vandenabeele, P., Heikenwälder, M., Dejardin, E.°: NIK promotes tissue
destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis. Cell
Death Differ. 22, 2020-2033 (2015)
Brandl, C., Ortiz, O., Röttig, B., Wefers, B., Wurst, W.°, Kühn, R.°: Creation of targeted genomic deletions
using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos. FEBS Open Bio 5, 26-35 (2015)
Braselmann, H.°, Michna, A., Hess, J., Unger, K.: CFAssay: Statistical analysis of the colony formation
assay. Radiat. Oncol. 10:223 (2015)
Bruns, H.°, Büttner, M., Fabri, M., Mougiakakos, D., Bittenbring, J.T., Hoffmann, M.H., Beier, F., Pasemann,
S., Jitschin, R., Hofmann, A.D., Neumann, F.J., Daniel, C., Maurberger, A., Kempkes, B., Amann, K.,
Mackensen, A., Gerbitz, A.: Vitamin D-dependent induction of cathelicidin in human macrophages results in
cytotoxicity against high-grade B cell lymphoma. Sci. Transl. Med. 7:282ra47 (2015)
Buck, A.#, Ly, A.#, Balluff, B., Sun, N., Gorzolka, K., Feuchtinger, A., Janssen, K.P., Kuppen, P.J., van de
Velde, C.J., Weirich, G., Erlmeier, F., Langer, R., Aubele, M., Zitzelsberger, H., Aichler, M., Walch, A.K.°:
High-resolution MALDI-FT-ICR MS imaging for the analysis of metabolites from formalin-fixed
paraffin-embedded clinical tissue samples. J. Pathol. 237, 123–132 (2015)
Bürck, C., Mund, A., Berscheminski, J., Kieweg, L., Müncheberg, S., Dobner, T., Schreiner, S.°: KAP1 is a
host restriction factor that promotes HAdV E1B-55K SUMO modification. J. Virol. 90, 930-946 (2015)
page 124 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Calzolari, F., Michel, J., Baumgart, E.V., Theis, F.J., Götz, M.°, Ninkovic, J.°: Fast clonal expansion and
limited neural stem cell self-renewal in the adult subependymal zone. Nat. Neurosci. 18, 490-492 (2015)
Canli, Ö., Alankus, Y.B., Grootjans, S., Vegi, N., Hültner, L., Hoppe, P.S., Schroeder, T., Vandenabeele, P.,
Bornkamm, G.W., Greten, F.R.°: Glutathione peroxidase 4 prevents necroptosis in mouse erythroid
precursors. Blood 127, 139-148 (2016) [published online 2015]
Cernilogar, F.M.°, di Giaimo, R., Rehfeld, F., Cappello, S., Lie, D.C.: RNA interference
machinery-mediated gene regulation in mouse adult neural stem cells. BMC Neurosci. 16:60 (2015)
Chaachouay, H., Fehrenbacher, B., Toulany, M., Schaller, M., Multhoff, G., Rodemann, H.P.°:
AMPK-independent autophagy promotes radioresistance of human tumor cells under clinical relevant
hypoxia in vitro. Radiother. Oncol. 116, 409-416 (2015)
Chege, M.W.°, Hashim, N.O., Merenga, A.S., Tschiersch, J.: Analysis of internal exposure associated with
consumption of crops and groundwater from the high background radiation area of Mrima Hill, Kenya.
Radiat. Prot. Dosim. 167, 276-278 (2015)
Chege, M.W.°, Hashim, N.O., Merenga, A.S., Meisenberg, O., Tschiersch, J.: Estimation of annual
effective dose due to radon and thoron concentrations in mud dwellings of Mrima Hill, Kenya. Radiat. Prot.
Dosim. 167, 139-142 (2015)
Chekkoury, A., Gateau, J., Driessen, W.H.P., Symvoulidis, P., Bézière, N., Feuchtinger, A., Walch,
A.K., Ntziachristos, V.°: Optical mesoscopy without the scatter: Broadband multispectral optoacoustic
mesoscopy. Biomed. Opt. Express 6, 3134-3148 (2015)
Chin, S.O., Hwang, J.K., Rhee, S.Y., Chon, S., Oh, S.S., Lee, M.S., Pellegata, N.S., Kim, S.W.°:
Acromegaly due to a macroinvasive plurihormonal pituitary adenoma and a rectal carcinoid tumor.
Endocrinol. Metab. 30, 389-394 (2015)
Combs, S.E.°: Individualized Radiotherapy (iRT) concepts for Locally Advanced Pancreatic Cancer (LAPC):
Indications and prognostic factors. Langenbecks Arch. Surg. 400, 749-756 (2015)
Combs, S.E.°, Engelhard, C., Kopp, C., Wiedenmann, N., Schramm, O., Prokic, V., Debus, J., Molls, M.,
Grosu, A.L.: Long-term outcome after highly advanced single-dose or fractionated radiotherapy in patients
with vestibular schwannomas - pooled results from 3 large German centers. Radiother. Oncol. 114, 378-383
(2015)
Cui, X., Luckenbaugh, L., Bruss, V., Hu, J.J.°: Alteration of mature nucleocapsid and enhancement of
covalently closed circular DNA formation by Hepatitis B Virus core mutants defective in complete virion
formation. J. Virol. 89, 10064-10072 (2015)
page 125 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Dargel, C., Bassani-Sternberg, M., Hasreiter, J., Zani, F., Bockmann, J.H., Thiele, F., Bohne, F.,
Wisskirchen, K., Wilde, S., Sprinzl, M.F., Schendel, D.J., Krackhardt, A.M., Uckert, W., Wohlleber, D.,
Schiemann, M., Stemmer, K., Heikenwälder, M., Busch, D.H., Richter, G., Mann, M., Protzer, U.°: T cells
engineered to express a T-cell receptor specific for glypican-3 to recognize and kill hepatoma cells in vitro
and in mice. Gastroenterology 149, 1042-1052 (2015)
de Bin, R.°, Herold, T., Boulesteix, A.-L.: Added predictive value of omics data: Specific issues related to
validation illustrated by two case studies. BMC Med. Res. Methodol. 14:117 (2014)
Degteva, M.O.°, Shagina, N.B., Shishkina, E.A.°, Vozilova, A.V., Volchkova, A.Y., Vorobiova, M.I., Wieser,
A., Fattibene, P., Della Monaca, S., Ainsbury, E.A., Moquet, J., Anspaugh, L.R., Napier, B.A.: Analysis of
EPR and FISH studies of radiation doses in persons who lived in the upper reaches of the Techa River.
Radiat. Environ. Biophys. 54, 433-444 (2015)
Dembek, C.J., Protzer, U.°: Mouse models for therapeutic vaccination against hepatitis B virus. Med.
Microbiol. Immunol. 204, 95-102 (2015)
#
#
Deng, T. , Zhu, Z.I. , Zhang, S., Postnikov, Y., Huang, D., Horsch, M., Furusawa, T., Beckers, J., Rozman,
J., Klingenspor, M., Amarie, O.V., Graw, J., Rathkolb, B., Wolf, E., Adler, T., Busch, D.H.,
Gailus-Durner, V., Fuchs, H., Hrabě de Angelis, M., van der Velde, A., Tessarollo, L., Ovcherenko, I.,
Landsman, D., Bustin, M.°: Functional compensation among HMGN variants modulates the DNase I
hypersensitive sites at enhancers. Genome Res. 25, 1295-1308 (2015)
Deppisch, N., Ruf, P., Eissler, N., Neff, F., Buhmann, R., Lindhofer, H., Mocikat, R.°: Efficacy and
tolerability of a GD2-directed trifunctional bispecific antibody in a preclinical model: Subcutaneous
administration is superior to intravenous delivery. Mol. Cancer Ther. 14, 1877-1883 (2015)
Diakopoulos, K.N., Lesina, M., Wörmann, S., Song, L., Aichler, M., Schild, L., Artati, A., Römisch-Margl,
W., Wartmann, T., Fischer, R., Kabiri, Y., Zischka, H., Halangk, W., Demir, I.E., Pilsak, C., Walch, A.K.,
Mantzoros, C.S., Steiner, J.M., Erkan, M., Schmid, R.M., Witt, H., Adamski, J., Algül, H.°: Impaired
autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.
Gastroenterology 148, 626-638 (2015)
Diener, S.#, Schorpp, K.K.#, Strom, T.M., Hadian, K.°, Lorenz-Depiereux, B.°: Development of a
cell-based assay to identify small molecule inhibitors of FGF23 signaling. Assay Drug Dev. Technol. 13,
476-487 (2015)
Dimou, L.°, Gallo, V.: NG2-glia and their functions in the central nervous system. Glia 63, 1429-1451 (2015)
Discher, M.°, Hiller, M., Woda, C.: MCNP simulations of a glass display used in a mobile phone as an
accident dosimeter. Radiat. Meas. 75, 21-28 (2015)
page 126 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Dorn, T., Goedel, A., Lam, J.T., Haas, J.A., Tian, Q., Herrmann, F., Bundschu, K., Dobreva, G., Schiemann,
M., Dirschinger, R.J., Guo, Y., Kühl, S.J., Sinnecker, D., Lipp, P., Laugwitz, K.L., Kühl, M., Moretti, A.°: Direct
Nkx2-5 transcriptional repression of Isl1 controls cardiomyocyte subtype identity. Stem Cells 33, 1113-1129
(2015)
Dutta, S., Krause, A., Vosberg, S., Herold, T., Ksienzyk, B., Quintanilla-Martinez, L., Tizazu, B., Chopra,
M., Graf, A., Krebs, S., Blum, H., Greif, P.A., Vetter, A., Metzeler, K.H., Rothenberg-Thurley, M., Schneider,
M.R., Dahlhoff, M., Spiekermann, K., Zimber-Strobl, U., Wolf, E., Bohlander, S.K.°: The target cell of
transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models. Leukemia,
DOI: 10.1038/leu.2015.349 (2015)
Ebrahimian, T.G.°, le Gallic, C., Stefani, J., Dublineau, I., Yentrapalli, R., Harms-Ringdahl, M., Haghdoost,
S.: Chronic gamma-irradiation induces a dose-rate-dependent pro-inflammatory response and associated
loss of function in human umbilical vein endothelial cells. Radiat. Res. 183, 447-454 (2015)
Eidemüller, M.°, Holmberg, E., Jacob, P., Lundell, M., Karlsson, P.: Breast cancer risk and possible
mechanisms of radiation-induced genomic instability in the Swedish hemangioma cohort after reanalyzed
dosimetry. Mutat. Res. 775, 1-9 (2015)
Eitelhuber, A.C., Vosyka, O., Nagel, D., Bognar, M., Lenze, D., Lammens, K., Schlauderer, F., Hlahla, D.,
Hopfner, K.P., Lenz, G., Hummel, M., Verhelst, S.H., Krappmann, D.°: Activity-based probes for detection of
active MALT1 paracaspase in immune cells and lymphomas. Chem. Biol. 22, 129-138 (2014)
Eke, I., Zscheppang, K., Dickreuter, E., Hickmann, L., Mazzeo, E., Unger, K., Krause, M., Cordes, N.°:
Simultaneous β1 integrin-EGFR targeting and radiosensitization of human head and neck cancer. J. Natl.
Cancer Inst. 107:dju419 (2015)
Erlmeier, F., Feuchtinger, A., Borgmann, D.M., Rudelius, M., Autenrieth, M., Walch, A.K., Weirich, G.°:
Supremacy of modern morphometry in typing renal oncocytoma and malignant look-alikes. Histochem. Cell
Biol. 144, 147-156 (2015)
Falkenberg, N.°, Anastasov, N., Schaub, A., Radulovic, V., Schmitt, M., Magdolen, V., Aubele, M.:
Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221. Oncotarget 6, 8103-8114 (2015)
Farah, J., Mares, V., Romero-Expósito, M., Trinkl, S., Domingo, C., Dufek, V., Klodowska, M., Kubančák, J.,
Knezevic, Z., Liszka, M., Majer, M., Miljanić, S., Ploc, O., Schinner, K., Stolarczyk, L., Trompier, F.,
Wielunski, M., Olko, P., Harrison, R.M.: Measurement of stray radiation within a scanning proton therapy
facility: EURADOS WG9 intercomparison exercise of active dosimetry systems. Med. Phys. 42, 2572-2584
(2015)
Fechner, S., Alvarez, L., Bönigk, W., Müller, A., Berger, T., Pascal, R., Trötschel, C., Poetsch, A., Stölting,
G., Siegfried, K.R., Kremmer, E., Seifert, R., Kaupp, U.B.: A K+ selective CNG channel orchestrates Ca2+
signalling in zebrafish sperm. eLife 4:e07624 (2015)
page 127 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Feederle, R., Klinke, O., Kutikhin, A., Poirey, R., Tsai, M.H., Delecluse, H.J.°: Epstein–barr virus: From the
detection of sequence polymorphisms to the recognition of viral types. Curr. Top. Microbiol. Immunol. 390,
119-148 (2015)
Filipczyk, A.#, Marr, C.#, Hastreiter, S.#, Feigelman, J., Schwarzfischer, M., Hoppe, P.S., Loeffler, D.,
Kokkaliaris, K.D., Endele, M., Schauberger, B., Hilsenbeck, O., Skylaki, S., Hasenauer, J.,
Anastassiadis, K., Theis, F.J.°, Schroeder, T.°: Network plasticity of pluripotency transcription factors in
embryonic stem cells. Nat. Cell Biol. 17, 1235-1246 (2015)
Filser, J.G.°, Artati, A., Li, Q., Pütz, C., Semder, B., Klein, D., Kessler, W.: Novel and existing data for a
future physiological toxicokinetic model of ethylene and its metabolite ethylene oxide in mouse, rat and
human. Chem. Biol. Interact. 241, 76-86 (2015)
Finkin, S., Yuan, D.T., Stein, I., Taniguchi, K., Weber, A., Unger, K., Browning, J.L., Goossens, N.,
Nakagawa, S., Gunasekaran, G., Schwartz, M.E., Kobayashi, M., Kumada, H., Berger, M., Pappo, O.,
Rajewsky, K., Hoshida, Y., Karin, M., Heikenwälder, M.°, Ben-Neriah, Y.°, Pikarsky, E.°: Ectopic lymphoid
structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nat. Immunol. 16,
1235-1244 (2015)
Fleck, D., Voss, M., Brankatschk, B., Giudici, C., Hampel, H., Schwenk, B.M., Edbauer, D., Fukumori, A.,
Steiner, H., Kremmer, E., Haug-Kröeper, M., Rossner, M.J., Fluhrer, R., Willem, M., Haass, C.: Proteolytic
processing of Neuregulin 1 type III by three intramembrane cleaving proteases. J. Biol. Chem. 291, 318-333
(2016) [published online 2015]
Flossdorf, M., Rössler, J., Buchholz, V.R., Busch, D.H., Höfer, T.°: CD8+ T cell diversification by asymmetric
cell division. Nat. Immunol. 16, 891-893 (2015)
#
#
Friberg, A. , Thumann, S. , Hennig, J., Zou, P., Nößner, E., Ling, P.D., Sattler, M.°, Kempkes, B.°: The
EBNA-2 N-terminal transactivation domain folds into a dimeric structure required for target gene activation.
PLoS Pathog. 11:e1004910 (2015)
Friedland, W., Kundrát, P.°: Chromosome aberration model combining radiation tracks, chromatin structure,
DSB repair and chromatin mobility. Radiat. Prot. Dosim. 166, 71-74 (2015)
Friedland, W.°, Kundrát, P., Schmitt, E.: Modelling proton bunches focussed to submicrometre scales:
Low-LET radiation damage in high-LET-like spatial structure. Radiat. Prot. Dosim. 166, 34-37 (2015)
Fukusumi, Y.#, Meier, F.#, Götz, S.#, Matheus, F., Irmler, M., Beckervordersandforth, R., Faus-Kessler, T.,
Minina, E., Rauser, B., Zhang, J., Arenas, E., Andersson, E.A., Niehrs, C., Beckers, J., Simeone, A.,
Wurst, W.°, Prakash, N.°: Dickkopf3 promotes the differentiation of a rostrolateral midbrain dopaminergic
neuronal subset in vivo and from pluripotent stem cells in vitro in the mouse. J. Neurosci. 35, 13385-13401
(2015)
page 128 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Garrett, L., Zhang, J., Zimprich, A., Niedermeier, K.M., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis,
M., Vogt Weisenhorn, D.M., Wurst, W., Hölter, S.M.°: Conditional reduction of adult born
doublecortin-positive neurons reversibly impairs selective behaviors. Front. Behav. Neurosci. 9:302 (2015)
Gascón, S.#°, Murenu, E.#, Masserdotti, G., Ortega, F., Russo, G.L., Petrik, D., Deshpande, A., Heinrich,
C., Karow, M., Robertson, S.P., Schroeder, T., Beckers, J., Irmler, M., Berndt, C., Friedmann Angeli, J.P.,
Conrad, M., Berninger, B., Götz, M.°: Identification and successful negotiation of a metabolic checkpoint in
direct neuronal repogramming. Cell Stem Cell 18, 396-409 (2016) [published online 2015]
Geipel, A., Seiz, P.L., Niekamp, H., Neumann-Fraune, M., Zhang, K., Kaiser, R., Protzer, U., Gerlich, W.H.,
Glebe, D.°, HOPE Consortium: Entecavir allows an unexpectedly high residual replication of HBV mutants
resistant to lamivudine. Antivir. Ther. (Lond.) 20, 779-787 (2016) [published online 2015]
Genitsch, V., Novotny, A., Seiler, C.A., Kröll, D., Walch, A.K., Langer, R.°: Epstein-Barr virus in
gastro-esophageal adenocarcinomas - single center experiences in the context of current literature. Front.
Oncol. 5:73 (2015)
Ghasemi, A., Jeddi-Tehrani, M.°, Mautner, J., Salari, M.H., Zarnani, A.H.°: Simultaneous immunization of
mice with Omp31 and TF provides protection against Brucella melitensis infection. Vaccine 33, 5532-5538
(2015)
Giannitrapani, L., Multhoff, G.°: The role of HSP70 in the diagnosis of HCC. Forum Immunopathol. Dis.
Therapeut. 5, 137-143 (2015)
#
#
Gnirß, K. , Zmora, P. , Blazejewska, P., Winkler, M., Lins, A., Nehlmeier, I., Gärtner, S., Moldenhauer, A.S.,
Hofmann-Winkler, H., Wolff, T., Schindler, M., Pöhlmann, S.°: Tetherin sensitivity of influenza A viruses is
strain specific: Role of hemagglutinin and neuraminidase. J. Virol. 89, 9178-9188 (2015)
God, J.M., Cameron, C., Figueroa, J., Amria, S., Hossain, A., Kempkes, B., Bornkamm, G.W., Stuart, R.K.,
Blum, J.S., Haque, A.°: Elevation of c-MYC disrupts HLA class II-mediated immune recognition of human B
cell tumors. J. Immunol. 194, 1434-1445 (2015)
Goldmann, T., Zeller, N., Raasch, J., Kierdorf, K., Frenzel, K., Ketscher, L., Basters, A., Staszewski, O.,
Brendecke, S.M., Spiess, A., Tay, T.L., Kreutz, C., Timmer, J., Mancini, G.M., Blank, T., Fritz, G., Biber, K.,
Lang, R., Malo, D., Merkler, D., Heikenwälder, M., Knobeloch, K.P., Prinz, M.°: USP18 lack in microglia
causes destructive interferonopathy of the mouse brain. EMBO J. 34, 1612-1629 (2015)
Gondim, M.V., Wiltzer-Bach, L., Maurer, B., Banning, C., Arganaraz, E., Schindler, M.°: AP-2 is the crucial
clathrin adaptor protein for CD4 downmodulation by HIV-1 Nef in primary infected CD4+ T cells. J. Virol. 89,
12518-12524 (2015)
Gottschalk, S., Estrada, H., Degtyaruk, O., Rebling, J., Klymenko, O., Rosemann, M., Razansky, D.°:
Short and long-term phototoxicity in cells expressing genetic reporters under nanosecond laser exposure.
Biomaterials 69, 38-44 (2015)
page 129 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Götz, M.°, Nakafuku, M., Petrik, D.: Neurogenesis in the developing and adult brain - similarities and key
differences. Cold Spring Harbor Perspect. Biol., DOI: 10.1101/cshperspect.a018853 (2015)
Götz, M.°, Sirko, S., Beckers, J., Irmler, M.: Reactive astrocytes as neural stem or progenitor cells: In vivo
lineage, In vitro potential, and genome-wide expression analysis. Glia 63, 1452-1468 (2015)
Graessel, A., Hauck, S.M., von Toerne, C., Kloppmann, E., Goldberg, T., Koppensteiner, H., Schindler,
M., Knapp, B., Krause, L., Dietz, K., Schmidt-Weber, C.B., Suttner, K.°: A combined omics approach to
+
generate the surface atlas of human naive CD4 T cells during early TCR activation. Mol. Cell. Proteomics
14, 2085-2102 (2015)
Gramolelli, S., Weidner-Glunde, M., Abere, B., Viejo-Borbolla, A., Bala, K., Rückert, J., Kremmer, E., Schulz,
T.F.°: Inhibiting the recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 protein reduces the
invasiveness and angiogenesis of infected endothelial cells. PLoS Pathog. 11:e1005105 (2015)
#
#
Grau, S.J. °, Trillsch, F. , Tonn, J.C., Goldbrunner, R.H., Nößner, E., Nelson, P.J., von Luettichau, I.:
Podoplanin increases migration and angiogenesis in malignant glioma. Int. J. Clin. Exp. Pathol. 8, 8663-8670
(2015)
Graw, J.°: From eyeless to neurological diseases. Exp. Eye Res., DOI: 10.1016/j.exer.2015.11.006 (2015)
#
#
#
Groß, C. , Steiger, K. , Sayyed, S. , Heid, I., Feuchtinger, A., Walch, A.K., Hess, J., Unger,
Zitzelsberger, H., Settles, M., Schlitter, A.M., Dworniczak, J., Altomonte, J., Ebert, O., Schwaiger,
Rummeny, E.J., Steingötter, A., Esposito, I., Braren, R.°: Model matters: Differences in orthotopic
hepatocellular carcinoma physiology determine therapy response to sorafenib. Clin. Cancer Res.
4440-4450 (2015)
K.,
M.,
rat
21,
Guenova, E.#°, Skabytska, Y.#, Hoetzenecker, W.#, Weindl, G., Sauer, K., Tham, M., Kim, K.W., Park, J.H.,
Seo, J.H., Ignatova, D., Cozzio, A., Levesque, M.P., Volz, T., Köberle, M., Kaesler, S., Thomas, P.,
Mailhammer, R., Ghoreschi, K., Schäkel, K., Amarov, B., Eichner, M., Schaller, M., Clark, R.A., Röcken,
M.°, Biedermann, T.°: IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in
antigen-presenting cells. Proc. Natl. Acad. Sci. U.S.A. 112, 2163-2168 (2015)
Gunther, S., Ostheimer, C., Stangl, S., Specht, H.M., Mozes, P., Jesinghaus, M., Vordermark, D., Combs,
S.E., Peltz, F., Jung, M.P., Multhoff, G.°: Correlation of Hsp70 serum levels with gross tumor volume and
composition of lmphocyte subpopulations in patients with squamous cell and adeno non-small cell lung
cancer. Front. Immunol. 6:556 (2015)
Haar, J., Contrant, M., Bernhardt, K., Feederle, R., Diederichs, S., Pfeffer, S., Delecluse, H.J.°: The
expression of a viral microRNA is regulated by clustering to allow optimal B cell transformation. Nucleic Acids
Res. 44, 1326-1341 (2016) [published online 2015]
Haase, K., Raffegerst, S.H., Schendel, D.J., Frishman, D.°: Expitope: A web server for epitope expression.
Bioinformatics 31, 1854-1856 (2015)
page 130 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Haep, L., Britzen-Laurent, N., Weber, T.G., Naschberger, E., Schaefer, A., Kremmer, E., Foersch, S., Vieth,
M., Scheuer, W., Wirtz, S., Waldner, M., Stürzl, M.°: Interferon gamma counteracts the angiogenic switch
and induces vascular permeability in dextran sulfate sodium colitis in mice. Inflamm. Bowel Dis. 21,
2360-2371 (2015)
Haftmann, C., Stittrich, A.B., Zimmermann, J., Fang, Z., Hradilkova, K., Bardua, M., Westendorf, K., Heinz,
G.A., Riedel, R., Siede, J., Lehmann, K., Weinberger, E.E., Zimmel, D., Lauer, U.M., Häupl, T., Sieper, J.,
Backhaus, M., Neumann, C., Hoffmann, U., Porstner, M., Chen, W., Grün, J.R., Baumgrass, R., Matz, M.,
Löhning, M., Scheffold, A., Wittmann, J., Chang, H., Rajewsky, N., Jack, H.M., Radbruch, A.H., Mashreghi,
M.F.°: MiR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the
proapoptotic gene Bim. Eur. J. Immunol. 45, 1192-1205 (2015)
Hain, K.°, Faestermann, T., Famulok, N., Fimiani, L., Gómez-Guzmán, J.M., Korschinek, G., Kortmann, F.,
Lierse, C., Ludwig, P., Shinonaga, T.: Analytical method for the determination of Np and Pu in sea water by
AMS with respect to the Fukushima accident. Nucl. Instrum. Methods Phys. Res. Sect. B 361, 505-509
(2015)
Hammerschmidt, W.°: The epigenetic life cycle of epstein–barr virus. Curr. Top. Microbiol. Immunol. 390,
103-117 (2015)
Hellfritsch, J., Kirsch, J., Schneider, M., Fluege, C., Wortmann, M., Frijhoff, J., Dagnell, M., Fey, T.,
Esposito, I., Kölle, P., Pogoda, K., Ingold, I., Angeli, J.P., Kuhlencordt, P., Östman, A., Pohl, U., Beck, H.°,
Conrad, M.°: Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits
tumor growth and tumor-derived angiogenesis. Antioxid. Redox Signal. 22, 938-950 (2015)
Helmbrecht, M.S.#, Soellner, H.#, Castiblanco-Urbina, M.A., Winzeck, S., Sundermeier, J., Theis, F.J.,
Fouad, K., Huber, A.B.°: A critical period for postnatal adaptive plasticity in a model of motor axon miswiring.
PLoS ONE 10:e0123643 (2015)
Helmbrecht, M.S.°, Soellner, H., Truckenbrodt, A.M., Sundermeier, J., Cohrs, C., Hans, W., Hrabě de
Angelis, M., Feuchtinger, A., Aichler, M., Fouad, K., Huber, A.B.°: Loss of Npn1 from motor neurons
causes postnatal deficits independent from Sema3A signaling. Dev. Biol. 399, 2-14 (2015)
Hensel, T., Giorgi, C., Schmidt, O., Calzada-Wack, J., Neff, F., Buch, T., Niggli, F.K., Schäfer, B.W.,
Burdach, S., Richter, G.H.: Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition
in Ewing sarcoma. Oncotarget 7, 1451-1463 (2016) [published online 2015]
Herranz, N., Gallage, S., Mellone, M., Wuestefeld, T., Klotz, S., Hanley, C.J., Raguz, S., Acosta, J.C., Innes,
A.J., Banito, A., Georgilis, A., Montoya, A., Wolter, K., Dharmalingam, G., Faull, P., Carroll, T.,
Martínez-Barbera, J.P., Cutillas, P., Reisinger, F., Heikenwälder, M., Miller, R.A., Withers, D., Zender, L.,
Thomas, G.J., Gil, J.°: mTOR regulates MAPKAPK2 translation to control the senescence-associated
secretory phenotype. Nat. Cell Biol. 17, 1205-1217 (2015)
page 131 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Heyne, K., Kölsch, K., Bruand, M., Kremmer, E., Grässer, F.A., Mayer, J., Roemer, K.: Np9, a cellular
protein of retroviral ancestry restricted to human, chimpanzee and gorilla, binds and regulates ubiquitin
ligase MDM2. Cell Cycle 14, 2619-2633 (2015)
Hoellein, A., Hecker, J., Hoffmann, D., Göttle, F., Protzer, U., Peschel, C., Götze, K.°: Serious outbreak of
human metapneumovirus in patients with hematologic malignancies. Leuk. Lymphoma 57, 623-627 (2016)
[published online 2015]
Hoffmann, T., Krackhardt, A.M., Antes, I.°: Quantitative analysis of the association angle between T-cell
receptor Vα/Vβ domains reveals important features for epitope recognition. PLoS Comput. Biol. 11:e1004244
(2015)
Hoh, A., Heeg, M., Ni, Y., Schuch, A., Binder, B., Hennecke, N., Blum, H.E., Nassal, M., Protzer, U.,
Hofmann, M., Urban, S., Thimme, R.°: HBV-infected HepG2hNTCP cells serve as a novel immunological tool to
analyze the antiviral efficacy of CD8+ T cells in vitro. J. Virol. 89, 7433-7438 (2015)
Holzerova, E., Danhauser, K., Haack, T.B., Kremer, L.S., Melcher, M., Ingold, I., Kobayashi, S., Terrile,
C., Wolf, P., Schaper, J., Mayatepek, E., Baertling, F., Friedmann Angeli, J.P., Conrad, M., Strom, T.M.,
Meitinger, T., Prokisch, H.°, Distelmaier, F.: Human thioredoxin 2 deficiency impairs mitochondrial redox
homeostasis and causes early-onset neurodegeneration. Brain 139, 346-354 (2016) [published online 2015]
page 132 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
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Hrabě de Angelis, M. , Nicholson, G. , Selloum, M. , White, J.K. , Morgan, H. , Ramirez-Solis, R. , Sorg,
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#
T. , Wells, S. , Fuchs, H. , Fray, M. , Adams, D.J., Adams, N.C., Adler, T., Aguilar-Pimentel, J.A.,
Ali-Hadji, D., Amann, G., André, P., Atkins, S., Auburtin, A., Ayadi, A., Becker, J., Becker, L., Bedu, E.,
Bekeredjian, R., Birling, M.C., Blake, A., Bottomley, J., Bowl, M.R., Brault, V., Busch, D.H., Bussell, J.N.,
Calzada-Wack, J., Cater, H., Champy, M.F., Charles, P., Chevalier, C., Chiani, F., Codner, G.F., Combe, R.,
Cox, R.D., Dalloneau, E., Dierich, A., di Fenza, A., Doe, B., Duchon, A., Eickelberg, O., Esapa, C.T., Fertak,
L.E., Feigel, T., Emelyanova, I., Estabel, J., Favor, J., Flenniken, A.M., Gambadoro, A., Garrett, L., Gates,
H., Gerdin, A.K., Gkoutos, G.V., Greenaway, S., Glasl, L., Goetz, P., da Cruz, I.G., Götz, A., Graw, J.,
Guimond, A., Hans, W., Hicks, G., Hölter, S.M., Höfler, H., Hancock, J.M., Hoehndorf, R., Hough, T.,
Houghton, R., Hurt, A., Ivandic, B., Jacobs, H., Jacquot, S., Jones, N., Karp, N.A., Katus, H.A., Kitchen, S.,
Klein-Rodewald, T., Klingenspor, M., Klopstock, T., Lalanne, V., Leblanc, S., Lengger, C., le Marchand,
E., Ludwig, T., Lux, A., McKerlie, C., Maier, H., Mandel, J.L., Marschall, S., Mark, M., Melvin, D.G.,
Meziane, H., Micklich, K., Mittelhauser, C., Monassier, L., Moulaert, D., Müller, S., Naton, B., Neff, F.,
Nolan, P.M., Nutter, L.M., Ollert, M., Pavlovic, G., Pellegata, N.S., Peter, E., Petit-Demoulière, B., Pickard,
A., Podrini, C., Potter, P., Pouilly, L., Puk, O., Richardson, D., Rousseau, S., Quintanilla-Fend, L., Quwailid,
M.M., Rácz, I., Rathkolb, B., Riet, F., Rossant, J., Roux, M., Rozman, J., Ryder, E., Salisbury, J., Santos,
L., Schäble, K.-H., Schiller, E., Schrewe, A., Schulz, H., Steinkamp, R., Simon, M., Stewart, M., Stöger,
C., Stöger, T., Sun, M., Sunter, D., Teboul, L., Tilly, I., Tocchini-Valentini, G.P., Tost, M., Treise, I.,
Vasseur, L., Velot, E., Vogt Weisenhorn, D.M., Wagner, C., Walling, A., Wattenhofer-Donze, M., Weber, B.,
Wendling, O., Westerberg, H., Willershäuser, M., Wolf, E., Wolter, A., Wood, J., Wurst, W., Yildirim, A.Ö.,
#
#
#
#
Zeh, R., Zimmer, A., Zimprich, A., Holmes, C. , Steel, K.P. , Herault, Y. , Gailus-Durner, V. , Mallon,
#
#
A.M. , Brown, S.D. °: Analysis of mammalian gene function through broad-based phenotypic screens across
a consortium of mouse clinics. Nat. Genet. 47, 969-978 (2015)
Hu, D., Mohanta, S.K., Yin, C., Peng, L., Ma, Z., Srikakulapu, P., Grassia, G., MacRitchie, N., Dever, G.,
Gordon, P.M., Burton, F.L., Ialenti, A., Sabir, S.R., McInnes, I.B., Brewer, J.M., Garside, P., Weber, C.,
Lehmann, T., Teupser, D., Habenicht, L., Beer, M., Grabner, R., Maffia, P., Weih, F., Habenicht, A.J.R.°:
Artery tertiary lymphoid organs control aorta immunity and protect against atherosclerosis via vascular
smooth muscle cell lymphotoxin β receptors. Immunity 42, 1100-1115 (2015)
#
#
#
Hüttl, R.E. , Luxenhofer, G. , Bianchi, E. , Haupt, C., Joshi, R., Prochiantz, A., Huber, A.B.°: Engrailed 1
mediates correct formation of limb innervation through two distinct mechanisms. PLoS ONE 10:e0118505
(2015)
Hüttl, R.E., Eckstein, S., Stahl, T., Petricca, S., Ninkovic, J., Götz, M., Huber, A.B.°: Functional dissection
of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development.
Dev. Biol., DOI: 10.1016/j.ydbio.2015.07.009 (2015)
Ingold, I., Aichler, M., Yefremova, E., Roveri, A., Buday, K., Doll, S., Tasdemir, A., Hoffard, N., Wurst,
W., Walch, A.K., Ursini, F., Friedmann Angeli, J.P., Conrad, M.°: Expression of a catalytically inactive
mutant form of Glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility. J. Biol.
Chem. 290, 14668-14678 (2015)
page 133 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Isernhagen, A., Schilling, D., Monecke, S., Shah, P., Elsner, L., Walter, L., Multhoff, G., Dressel, R.: The
MICA-129Met/Val dimorphism affects plasma membrane expression and shedding of the NKG2D ligand
MICA. Immunogenetics 68, 109-123 (2015)
Jacobi, C.°, Ayx, I., Fritsche, K., Piontek, G., Hoffmann, D., Weirich, G., Knopf, A.: Potential impact of
human papilloma virus on survival of basaloid squamous carcinoma of the head and neck. Oncotarget 6,
3462-3470 (2015)
Joekel, D., Hinse, P., Raulf, M.K., Schicht, S., Bäumer, W., Werling, D., Kremmer, E., Strube, C.:
Vaccination of calves with yeast- and bacterial-expressed paramyosin from the bovine lungworm
Dictyocaulus viviparus. Parasite Immunol. 37, 614-623 (2015)
Jors, S., Jeliazkova, P., Ringelhan, M., Thalhammer, J., Dürl, S., Ferrer, J., Sander, M., Heikenwälder, M.,
Schmid, R.M., Siveke, J.T., Geisler, F.°: Lineage fate of ductular reactions in liver injury and carcinogenesis.
J. Clin. Invest. 125, 2445-2457 (2015)
Kagan, V.E.°, Tyurina, Y.Y., Tyurin, V.A., Mohammadyani, D., Friedmann Angeli, J.P., Baranov, S.V.,
Klein-Seetharaman, J., Friedlander, R.M., Mallampalli, R.K., Conrad, M., Bayir, H.: Cardiolipin signaling
mechanisms: Collapse of asymmetry and oxidation. Antioxid. Redox Signal. 22, 1667-1680 (2015)
Kandemir, M., Feuchtinger, A., Walch, A.K., Hamprecht, F.A.: Digital pathology: Multiple instance learning
can detect Barrett's cancer. In: (IEEE International Symposium on Biomedical Imaging, ISBI). Piscataway,
NJ: IEEE, 2014, 1348-1351
Keipert, S., Kutschke, M., Lamp, D., Brachthäuser, L., Neff, F., Meyer, C.W., Oelkrug, R., Kharitonenkov,
A., Jastroch, M.°: Genetic disruption of uncoupling protein 1 in mice renders brown adipose tissue a
significant source of FGF21 secretion. Mol. Metab. 4, 537-542 (2015)
Keller, I.E., Vosyka, O., Takenaka, S., Kloß, A., Dahlmann, B., Willems, L.I., Verdoes, M., Overkleeft, H.S.,
Marcos, E., Adnot, S., Hauck, S.M., Ruppert, C., Günther, A., Herold, S., Ohno, S., Adler, H., Eickelberg,
O., Meiners, S.°: Regulation of immunoproteasome function in the lung. Sci. Rep. 5:10230 (2015)
Kellner, M., Rohrmoser, M., Forne, I., Voss, K., Burger, K., Mühl, B., Gruber-Eber, A., Kremmer, E.,
Imhof, A., Eick, D.°: DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S RNA and stably
associates with the PeBoW-complex. Exp. Cell Res. 334, 146-159 (2015)
Kempf, S.J., von Toerne, C., Hauck, S.M., Atkinson, M.J., Benotmane, M.A., Tapio, S.°: Long-term
consequences of in utero irradiated mice indicate proteomic changes in synaptic plasticity related signalling.
Proteome Sci. 13:26 (2016) [published online 2015]
Kempf, S.J., Mörtl, S., Sepe, S., von Toerne, C., Hauck, S.M., Atkinson, M.J., Mastroberardino, P.G.,
Tapio, S.°: Low-dose ionizing radiation rapidly affects mitochondrial and synaptic signaling pathways in
murine hippocampus and cortex. J. Proteome Res. 14, 2055-2064 (2015)
page 134 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Kempf, S.J., Sepe, S., von Toerne, C., Janik, D., Neff, F., Hauck, S.M., Atkinson, M.J., Mastroberardino,
P.G., Tapio, S.°: Neonatal irradiation leads to persistent proteome alterations involved in synaptic plasticity
in the mouse hippocampus and cortex. J. Proteome Res. 14, 4674-4686 (2015)
Kempkes, B.°, Ling, P.D.°: EBNA2 and its coactivator EBNA-LP. Curr. Top. Microbiol. Immunol. 391, 35-39
(2015)
Kempkes, B.°, Robertson, E.S.: Epstein-Barr virus latency: Current and future perspectives. Curr. Opin.
Virol. 14, 138-144 (2015)
Kerr, G.D., Egbert, S.D., Al-Nabulsi, I.°, Bailiff, I.K., Beck, H.L., Belukha, I.G., Cockayne, J.E., Cullings, H.M.,
Eckerman, K.F., Granovskaya, E., Grant, E.J., Hoshi, M., Kaul, D.C., Kryuchkov, V., Mannis, D., Ohtaki, M.,
Otani, K., Shinkarev, S., Simon, S.L., Spriggs, G.D., Stepanenko, V.F., Stricklin, D., Weiss, J.F., Weitz, R.L.,
Woda, C., Worthington, P.R., Yamamoto, K., Young, R.W.: Workshop report on atomic bomb dosimetry:
Review of dose related factors for the evaluation of exposures to residual radiation at Hiroshima and
Nagasaki. Health Phys. 109, 582-600 (2015)
Kessel, K.A., Combs, S.E.: Data management, documentation and analysis systems in radiation oncology:
A multi-institutional survey. Radiat. Oncol. 10:230 (2015)
Kessler, T.#, Zhang, L.#, Liu, Z., Yin, X., Huang, Y., Wang, Y., Fu, Y., Mayr, M., Ge, Q., Xu, Q., Zhu, Y.,
Wang, X., Schmidt, K.J., de Wit, C., Erdmann, J., Schunkert, H., Aherrahrou, Z#°, Kong, W.#°, German
Mouse Clinic Consortium (Adamski, J., Adler, T., Aguilar-Pimentel, J.A., Amarie, O.V., Becker, L.,
Beckers, J., Brachthäuser, L., Busch, D.H., Calzada-Wack, J., Eickelberg, O., Fuchs, H.,
Gailus-Durner, V., Garrett, L., Graw, J., Hans, W., Hölter, S.M., Horsch, M., Hrabě de Angelis, M.,
Janik, D., Klein-Rodewald, T., Klingenspor, M., Klopstock, T., Lengger, C., Leuchtenberger, S., Maier,
H., Moreth, K., Neff, F., Ollert, M., Prehn, C., Puk, O., Rathkolb, B., Rozman, J., Steinkamp, R., Stöger,
C., Stöger, T., Vernaleken, A.M., Yildirim, A.Ö., Wurst, W., Zimprich, A.): ADAMTS-7 inhibits
re-endothelialization of injured arteries and promotes vascular remodeling via cleavage of thrombospondin-1.
Circulation 131, 1191-1201 (2015)
Kiermayer, C.°, Northrup, E., Schrewe, A., Walch, A.K., Hrabě de Angelis, M., Schoensiegel, F.,
Zischka, H., Prehn, C., Adamski, J., Bekeredjian, R., Ivandic, B., Kupatt, C., Brielmeier, M.: Heart-specific
knockout of the mitochondrial Thioredoxin reductase (Txnrd2) induces metabolic and contractile dysfunction
in the aging myocardium. J. Am. Heart Assoc. 4:e002153 (2015)
Kieser, A.°, Sterz, K.: The Latent Membrane Protein 1 (LMP1). Curr. Top. Microbiol. Immunol. 391, 119-149
(2015)
Klein, D., Schmetter, A., Imsak, R., Wirsdörfer, F., Unger, K., Jastrow, H., Stuschke, M., Jendrossek, V.°:
Therapy with multipotent mesenchymal stromal cells protects lungs from radiation-induced injury and
reduces the risk of lung metastasis. Antioxid. Redox Signal. 24, 53-69 (2015)
page 135 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Kobayashi, S., Sato, M., Kasakoshi, T., Tsutsui, T., Sugimoto, M., Osaki, M., Okada, F., Igarashi, K.,
Hiratake, J., Homma, T., Conrad, M., Fujii, J., Soga, T., Bannai, S., Sato, H.°: Cystathionine is a novel
substrate of cystine/glutamate transporter: Implications for immune function. J. Biol. Chem. 290, 8778-8788
(2015)
Köhnke, T., Krupka, C., Tischer, J., Knösel, T., Subklewe, M.°: Increase of PD-L1 expressing B-precursor
ALL cells in a patient resistant to the CD19/CD3-bispecific T cell engager antibody blinatumomab. J.
Hematol. Oncol. 8:111 (2015)
Kovac, M., Blattmann, C., Ribi, S., Smida, J., Müller, N.S., Engert, F., Castro-Giner, F., Weischenfeldt, J.,
Kovacova, M., Krieg, A., Andreou, D., Tunn, P.U., Dürr, H.R., Rechl, H.P., Schaser, K.D., Melcher, I.,
Burdach, S., Kulozik, A., Specht, K., Heinimann, K., Fulda, S., Bielack, S., Jundt, G., Tomlinson, I., Korbel,
J.O., Nathrath, M., Baumhoer, D.: Exome sequencing of osteosarcoma reveals mutation signatures
reminiscent of BRCA deficiency. Nat. Commun. 6:8940 (2015)
Kovalchuk, Y., Homma, R., Liang, Y., Maslyukov, A., Hermes, M., Thestrup, T., Griesbeck, O., Ninkovic, J.,
Cohen, L.B., Garaschuk, O.°: In vivo odourant response properties of migrating adult-born neurons in the
mouse olfactory bulb. Nat. Commun. 6:6349 (2015)
Kreuzer, M.°, Auvinen, A., Cardis, E., Hall, J., Jourdain, J.R., Laurier, D., Little, M.P., Peters, A., Raj, K.,
Russell, N.S., Tapio, S., Zhang, W., Gomolka, M.: Low-dose ionising radiation and cardiovascular diseases
– strategies for molecular epidemiological studies in Europe. Mutat. Res.- Rev. Mutat. Res. 764, 90-100
(2015)
Krupka, C., Kufer, P., Kischel, R., Zugmaier, G., Lichtenegger, F.S., Köhnke, T., Vick, B., Jeremias, I.,
Metzeler, K.H., Altmann, T., Schneider, S., Fiegl, M., Spiekermann, K., Baeuerle, P.A., Hiddemann, W.,
Riethmüller, G., Subklewe, M.°: Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the
CD33/CD3-BiTE antibody construct AMG 330: Reversing a T-cell induced immune escape mechanism.
Leukemia 30, 484-491 (2016) [published online 2015]
Kundrát, P.°, Friedland, W.: Impact of intercellular induction of apoptosis on low-dose radiation
carcinogenesis. Radiat. Prot. Dosim. 166, 170-173 (2015)
Kundrát, P.°, Friedland, W.: Mechanistic modelling of radiation-induced bystander effects. Radiat. Prot.
Dosim. 166, 148-151 (2015)
Kunze, S., Dalke, C., Fuchs, H., Klaften, M., Rössler, U., Hornhardt, S., Gomolka, M., Puk, O., Sabrautzki,
S., Kulka, U., Hrabě de Angelis, M., Graw, J.°: New mutation in the mouse Xpd/Ercc2 gene leads to
recessive cataracts. PLoS ONE 10:e0125304 (2015)
Kurek, D., Neagu, A., Tastemel, M., Tüysüz, N., Lehmann, J., van de Werken, H.J.G., Philipsen, S., van der
Linden, R., Maas, A., van IJcken, W.F.J., Drukker, M., ten Berge, D.°: Endogenous WNT signals mediate
BMP-induced and spontaneous differentiation of epiblast stem cells and human embryonic stem cells. Stem
Cell Rep. 4, 114-128 (2015)
page 136 of 213
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Kyrousi, C., Arbi, M., Pilz, G.-A., Pefani, D.E., Lalioti, M.E., Ninkovic, J., Götz, M., Lygerou, Z., Taraviras,
S.°: Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult
neurogenic niche. Development 142, 3661-3674 (2015)
Labazi, M., McNeil, A.K., Kurtz, T., Lee, T.C., Pegg, R.B., Friedmann Angeli, J.P., Conrad, M., McNeil,
P.L.°: The antioxidant requirement for plasma membrane repair in skeletal muscle. Free Radic. Biol. Med.
84, 246-253 (2015)
Lagouge, M., Mourier, A., Lee, H.J., Spåhr, H., Wai, T., Kukat, C., Silva Ramos, E., Motori, E., Busch, J.D.,
Siira, S., German Mouse Clinic Consortium (Larsson, N.G.°, Aguilar-Pimentel, J.A., Amarie, O.V., Becker,
L., Beckers, J., Brachthäuser, L., Calzada-Wack, J., Eickelberg, O., Gailus-Durner, V., Garrett, L.,
Graw, J., Hans, W., Hölter, S.M., Horsch, M., Hrabě de Angelis, M., Janik, D., Klein-Rodewald, T.,
Lengger, C., Leuchtenberger, S., Maier, H., Moreth, K., Neff, F., Östereicher, M., Puk, O., Rácz, I.,
Rathkolb, B., Rozman, J., Steinkamp, R., Stöger, C., Stöger, T., Vernaleken, A.M., Wurst, W., Yildirim,
A.Ö., Zimprich, A.), Kremmer, E., Filipovska, A.°: SLIRP regulates the rate of mitochondrial protein
synthesis and protects LRPPRC from degradation. PLoS Genet. 11:e1005423 (2015)
Lahiri, S., Sun, N., Solis-Mezarino, V., Fedisch, A., Ninkovic, J., Feuchtinger, A., Götz, M., Walch, A.K.,
Imhof, A.°: In situ detection of histone variants and modifications in mouse brain using imaging mass
spectrometry. Proteomics 16, 437-447 (2016) [published online 2015]
Lahm, H.°, Doppler, S.A., Dressen, M., Werner, A., Adamczyk, K., Schrambke, D., Brade, T., Laugwitz, K.L.,
Deutsch, M.A., Schiemann, M., Lange, R., Moretti, A., Krane, M.: Live fluorescent RNA-based detection of
pluripotency gene expression in embryonic and induced pluripotent stem cells of different species. Stem
Cells 33, 392-402 (2015)
Lambelé, M., Koppensteiner, H., Symeonides, M., Roy, N.H., Chan, J., Schindler, M., Thali, M.°: Vpu is the
main determinant for tetraspanin downregulation in HIV-1 infected cells. J. Virol. 89, 3247-3255 (2015)
Lee, M.S., Wiedemann, T., Gross, C., Leinhäuser, I., Roncaroli, F., Braren, R., Pellegata, N.S.°: Targeting
PI3K/mTOR signaling displays potent antitumor efficacy against nonfunctioning pituitary adenomas. Clin.
Cancer Res. 21, 3204-3215 (2015)
Leinhäuser, I., Richter, A., Lee, M.S., Höfig, I., Anastasov, N., Fend, F., Ercolino, T., Mannelli, M.,
Gimenez-Roqueplo, A.P., Robledo, M., de Krijger, R.R., Beuschlein, F., Atkinson, M.J., Pellegata, N.S.°:
Oncogenic features of the Bone Morphogenic Protein 7 (BMP7) in pheochromocytoma. Oncotarget 6,
39111-39126 (2015)
#
#
#
Lemmermann, N.A.W. , Krmpotic, A. , Podlech, J. , Brizic, I., Prager, A., Adler, H., Karbach, A., Wu, Y.,
Jonjic, S., Reddehase, M.J., Adler, B.°: Non-redundant and redundant roles of cytomegalovirus gH/gL
complexes in host organ entry and intra-tissue spread. PLoS Pathog. 11:e1004640 (2015)
Li, C.°, Hauck, B., Capello, K., Nogueira, P., Lopez, M.A., Kramer, G.H.: Counting 241Am in the BfS human
skull phantom on contact - evaluation in the human monitoring laboratory. Health Phys. 108, 380-382 (2015)
page 137 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Li, W.B.°, Klein, W., Blanchardon, E., Puncher, M., Leggett, R.W., Oeh, U., Breustedt, B., Noßke, D., López,
M.A.: Parameter uncertainty analysis of a biokinetic model of caesium. Radiat. Prot. Dosim. 163, 37-57
(2015)
Lichtenegger, F.S., Krupka, C., Köhnke, T., Subklewe, M.°: Immunotherapy for acute myeloid leukemia.
Semin. Hematol. 52, 207-214 (2015)
Lichtenegger, F.S.°, Kondla, I., Krempasky, M., Weber, A.L., Herold, T., Krupka, C., Spiekermann, K.,
Schneider, S., Büchner, T., Berdel, W.E., Wörmann, B.J., Hiddemann, W., Subklewe, M.: RNA and protein
expression of Herpesvirus Entry Mediator (HVEM) is associated with molecular markers, immunity-related
pathways and relapse-free survival of patients with AML. Cancer Immunol. Immunother. 64, 1505-1515
(2015)
Lin, H.-C., Chekkoury, A., Omar, M., Schmitt-Manderbach, T., Koberstein-Schwarz, B., Mappes, T.,
López-Schier, H., Razansky, D., Ntziachristos, V.°: Selective plane illumination optical and optoacoustic
microscopy for postembryonic imaging. Laser Photon. Rev. 9, L29-L34 (2015)
#
#
Lin, X. , Tsai, M.H. , Shumilov, A., Poirey, R., Bannert, H., Middeldorp, J.M., Feederle, R., Delecluse, H.J.°:
The Epstein-Barr virus BART miRNA cluster of the M81 strain modulates multiple functions in primary B
cells. PLoS Pathog. 11:e1005344 (2015)
Linder, K., Schleger, F., Kiefer-Schmidt, I., Fritsche, L., Kümmel, S., Heni, M., Weiss, M., Häring, H.-U.,
Preissl, H.°, Fritsche, A.: Gestational diabetes impairs human fetal postprandial brain activity. J. Clin.
Endocrinol. Metab. 100, 4029-4036 (2015)
Linnemann, J., Miura, H., Meixner, L.K., Irmler, M., Kloos, U., Hirschi, B., Bartsch, H.S., Sass, S.,
Beckers, J., Theis, F.J., Gabka, C., Sotlar, K., Scheel, C.°: Quantification of regenerative potential in
primary human mammary epithelial cells. Development 142, 3239-3251 (2015)
Linzen, U., Lilischkis, R., Pandithage, R., Schilling, B., Ullius, A., Luscher-Firzlaff, J., Kremmer, E., Lüscher,
B.°, Vervoorts, J.°: ING5 is phosphorylated by CDK2 and controls cell proliferation independently of p53.
PLoS ONE 10:e0123736 (2015)
Loffredo-Verde, E., Abdel-Aziz, I.Z., Albrecht, J., El Guindy, N.M., Yacob, M., Solieman, A.S., Protzer, U.,
Busch, D.H., Layland, L.E., Prazeres da Costa, C.U.: Schistosome infection aggravates HCV-related liver
disease and induces changes in the regulatory T-cell phenotype. Parasite Immunol. 37, 97-104 (2015)
Lorenz, F.K., Wilde, S., Voigt, K., Kieback, E., Mosetter, B., Schendel, D.J., Uckert, W.°: Codon
optimization of the human papillomavirus E7 oncogene induces a CD8+ T cell response to a cryptic epitope
not harbored by wild-type E7. PLoS ONE 10:e0121633 (2015)
Mackenzie, I.R., Frick, P., Grässer, F.A., Gendron, T.F., Petrucelli, L., Cashman, N.R., Edbauer, D.,
Kremmer, E., Prudlo, J., Troost, D., Neumann, M.°: Quantitative analysis and clinico-pathological
correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers. Acta
Neuropathol. 130, 845-861 (2015)
page 138 of 213
31.12.2015
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° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Magin, S., Papaioannou, M., Saha, J., Staudt, C., Iliakis, G.°: Inhibition of homologous recombination and
promotion of mutagenic repair of DNA double-strand breaks underpins arabinoside-nucleoside analogue
radiosensitization. Mol. Cancer Ther. 14, 1424-1433 (2015)
Mancuso, M.°, Pasquali, E., Braga-Tanaka III, I., Tanaka, S., Pannicelli, A., Giardullo, P., Pazzaglia, S.,
Tapio, S., Atkinson, M.J., Saran, A.°: Acceleration of atherogenesis in ApoE-/- mice exposed to acute or
low-dose-rate ionizing radiation. Oncotarget 6, 31263-31271 (2015)
Marcos, S., González-Lázaro, M., Beccari, L., Carramolino, L., Martin-Bermejo, M.J., Amarie, O.V., Martín,
D.M., Torroja, C., Bogdanović, O., Doohan, R., Puk, O., Hrabě de Angelis, M., Graw, J., Gómez-Skarmeta,
J.L., Casares, F., Torres, M.°, Bovolenta, P.°: Meis1 coordinates a network of genes implicated in eye
development and microphthalmia. Development 142, 3009-3020 (2015)
Martinez, G.J., Pereira, R.M., Äijö, T., Kim, E.Y., Marangoni, F., Pipkin, M.E., Togher, S., Heissmeyer, V.,
Zhang, Y.C., Crotty, S., Lamperti, E.D., Ansel, K.M., Mempel, T.R., Lähdesmäki, H.°, Hogan, P.G., Rao, A.°:
The transcription factor NFAT promotes exhaustion of activated CD8+ T Cells. Immunity 42, 265–278 (2015)
#
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Masserdotti, G. , Gillotin, S. , Sutor, B., Drechsel, D., Irmler, M., Jørgensen, H.F., Sass, S., Theis, F.J.,
Beckers, J., Berninger, B., Guillemot, F.°, Götz, M.°: Transcriptional mechanisms of proneural factors and
REST in regulating neuronal reprogramming of astrocytes. Cell Stem Cell 17, 74-88 (2015)
Matheson, N.J.°, Sumner, J., Wals, K., Rapiteanu, R., Weekes, M.P., Vigan, R., Weinelt, J., Schindler, M.,
Antrobus, R., Costa, A.S.H., Frezza, C., Clish, C.B., Neil, S.J.D., Lehner, P.J.°: Cell surface proteomic map
of HIV infection reveals antagonism of amino acid metabolism by Vpu and Nef. Cell Host Microbe 18,
409-423 (2015)
Matsushita, M., Freigang, S., Schneider, C., Conrad, M., Bornkamm, G.W., Kopf, M.°: T cell lipid
peroxidation induces ferroptosis and prevents immunity to infection. J. Exp. Med. 212, 555-568 (2015)
Maugg, D.°, Rothenaigner, I., Schorpp, K.K., Potukuchi, H.K., Korsching, E., Baumhoer, D., Hadian, K.,
Smida, J., Nathrath, M.: New small molecules targeting apoptosis and cell viability in osteosarcoma. PLoS
ONE 10:e0129058 (2015)
Meisenberg, O.°, Tschiersch, J.°: Test of methods for retrospective activity size distribution determination
from filter samples. Radiat. Meas. 76, 29-35 (2015)
Meredith, L.W.#, Hu, K.#, Cheng, X., Howard, C.R., Baumert, T.F., Balfe, P., van de Graaf, K.F., Protzer, U.,
McKeating, J.A.°: Lentiviral hepatitis B pseudotype entry requires NTCP and additional hepatocyte-specific
factors. J. Gen. Virol. 97, 121-127 (2016) [published online 2015]
Miras, A., Mogford, J.T., Wright, J.E.°, Mendoza, N.N., Xekouki, P., Lakhani, A., Pellegata, N.S., Stratakis,
C.A., Roncaroli, F., Russell-Jones, D.L.: Ovarian hyperstimulation from ectopic hypersecretion of follicle
stimulating hormone. Lancet 385, 392 (2015)
page 139 of 213
31.12.2015
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#
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#
#
Mu, X. , Español-Suñer, R. , Mederacke, I., Affò, S., Manco, R., Sempoux, C., Lemaigre, F.P., Adili, A.,
Yuan, D.T., Weber, A., Unger, K., Heikenwälder, M., Leclercq, I.A., Schwabe, R.F.°: Hepatocellular
carcinoma originates from hepatocytes and not from the progenitor/biliary compartment. J. Clin. Invest. 125,
3891-3903 (2015)
Mulholland, C.B., Smets, M., Schmidtmann, E., Leidescher, S., Markaki, Y., Hofweber, M., Qin, W., Manzo,
M., Kremmer, E., Thanisch, K., Bauer, C., Rombaut, P., Herzog, F., Leonhardt, H., Bultmann, S.°: A
modular open platform for systematic functional studies under physiological conditions. Nucleic Acids Res.
43:e112 (2015)
Müllner, M., Schlattl, H., Hoeschen, C., Dietrich, O.°: Feasibility of spectral CT imaging for the detection of
liver lesions with gold-based contrast agents - a simulation study. Phys. Med. 31, 875-881 (2015)
Multhoff, G.°, Pockley, A.G., Schmid, T.E., Schilling, D.: The role of Heat shock protein 70 (Hsp70) in
radiation-induced immunomodulation. Cancer Lett. 368, 179-184 (2015)
Murakami, N., Kühnel, A., Schmid, T.E., Ilicic, K., Stangl, S., Braun, I.S., Gehrmann, M., Molls, M., Itami, J.,
Multhoff, G.°: Role of membrane Hsp70 in radiation sensitivity of tumor cells. Radiat. Oncol. 10:149 (2015)
Nagel, D., Bognar, M., Eitelhuber, A.C., Kutzner, K., Vincendeau, M., Krappmann, D.°: Combinatorial
BTK and MALT1 inhibition augments killing of CD79 mutant diffuse large B cell lymphoma. Oncotarget 6,
42232-42242 (2015)
Nagel, D., Krappmann, D.°: Detection of recombinant and cellular MALT1 paracaspase activity. Methods
Mol. Biol. 1280, 239-246 (2015)
Naves, L.A., Daly, A.F., Dias, L.A., Yuan, B., Zakir, J.C., Barra, G.B., Palmeira, L., Villa, C., Trivellin, G.,
Júnior, A.J., Neto, F.F., Liu, P.P., Pellegata, N.S., Stratakis, C.A., Lupski, J.R., Beckers, A.: Aggressive
tumor growth and clinical evolution in a patient with X-linked acro-gigantism syndrome. Endocrine 51,
236-244 (2015)
Neumann, M., Vosberg, S., Schlee, C., Heesch, S., Schwartz, S., Gökbuget, N., Hoelzer, D., Graf, A.,
Krebs, S., Bartram, I., Blum, H., Brüggemann, M., Hecht, J., Bohlander, S.K., Greif, P.A., Baldus, C.D.°:
Mutational spectrum of adult T-ALL. Oncotarget 6, 2754-2766 (2014)
Nguyen, T.T., Yeom, Y.S., Kim, H.S., Wang, Z.J., Han, M.C., Kim, C.H.°, Lee, J.K., Zankl, M.,
Petoussi-Henß, N., Bolch, W.E., Lee, C., Chung, B.S.: Incorporation of detailed eye model into
polygon-mesh versions of ICRP-110 reference phantoms. Phys. Med. Biol. 60, 8695-8707 (2015)
Nogueira, P.°, Rühm, W., Lopez, M.A., Vrba, T., Buchholz, W., Fojtik, P., Etherington, G., Broggio, D.,
Huikari, J., Marzocchi, O., Lynch, T., Lebacq, A.L., Li, C., Os̈ko, J., Malatova, I., Franck, D., Breustedt, B.,
Leone, D., Scott, J., Shutt, A.L., Hauck, B., Capello, K., Pérez-López, B., Navarro-Amaro, J.F., Pliszczyński,
241
T., Fantínová, K., Tolmachev, S.Y.: EURADOS Am skull measurement intercomparison. Radiat. Meas. 82,
64-73 (2015)
page 140 of 213
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Nowicka, A.M., Häuselmann, I., Borsig, L., Bolduan, S., Schindler, M., Schraml, P., Heikenwälder, M.°,
Moch, H.°: A novel pVHL-independent but NEMO-driven pathway in renal cancer promotes HIF stabilization.
Oncogene, DOI: 10.1038/onc.2015.400 (2015)
O'Connor, T.°, Borsig, L., Heikenwälder, M.°: CCL2-CCR2 signaling in disease pathogenesis. Endocr.
Metab. Immune Disord. Drug Targets 15, 105-118 (2015)
O'Leary, V.B.°, Ovsepian, S.V., Carrascosa, L.G., Buske, F.A., Radulovic, V., Niyazi, M., Mörtl, S., Trau,
M., Atkinson, M.J., Anastasov, N.: PARTICLE, a triplex-forming long ncRNA, regulates locus-specific
methylation in response to low-dose irradiation. Cell Rep. 11, 474-485 (2015)
Oechsner, M., Odersky, L., Berndt, J., Combs, S.E., Wilkens, J.J., Duma, M.N.: Dosimetric impact of
different CT datasets for stereotactic treatment planning using 3D conformal radiotherapy or volumetric
modulated arc therapy. Radiat. Oncol. 10:249 (2015)
Oetjen, J., Veselkov, K., Watrous, J., McKenzie, J.S., Becker, M., Hauberg-Lotte, L., Kobarg, J.H.,
Strittmatter, N., Mróz, A.K., Hoffmann, F., Trede, D., Palmer, A., Schiffler, S., Steinhorst, K., Aichler, M.,
Goldin, R., Guntinas-Lichius, O., von Eggeling, F., Thiele, H., Maedler, K., Walch, A.K., Maass, P.,
Dorrestein, P.C., Takats, Z., Alexandrov, T.°: Benchmark datasets for 3D MALDI- and DESI-imaging mass
spectrometry. GigaScience 4:20 (2015)
Orabi, A., Bieringer, M., Geerlof, A., Bruss, V.°: An aptamer against the matrix binding domain on the
hepatitis B virus capsid impairs virion formation. J. Virol. 89, 9281-9287 (2015)
Ovsepian, S.V.°, O'Leary, V.B., Zaborszky, L.: Cholinergic mechanisms in the cerebral cortex: Beyond
synaptic transmission. Neuroscientist, DOI: 10.1177/1073858415588264 (2015)
Ovsepian, S.V.°, Bodeker, M.O., O'Leary, V.B., Lawrence, G.W., Dolly, J.O.: Internalization and retrograde
axonal trafficking of tetanus toxin in motor neurons and trans-synaptic propagation at central synapses
exceed those of its C-terminal-binding fragments. Brain Struct. Funct. 220, 1825-1838 (2015)
Ovsepian, S.V.°, O'Leary, V.B.: Neuronal activity and amyloid plaque pathology: An update. J. Alzheimers
Dis. 49, 13-19 (2015)
Pastore, A., Jurinovic, V., Kridel, R., Hoster, E., Staiger, A.M., Szczepanowski, M., Pott, C., Kopp, N.,
Murakami, M., Horn, H., Leich, E., Moccia, A.A., Mottok, A., Sunkavalli, A., van Hummelen, P., Ducar, M.,
Ennishi, D., Shulha, H.P., Hother, C., Connors, J.M., Sehn, L.H., Dreyling, M., Neuberg, D., Möller, P., Feller,
A.C., Hansmann, M.L., Stein, H., Rosenwald, A., Ott, G., Klapper, W., Unterhalt, M., Hiddemann, W.,
Gascoyne, R.D., Weinstock, D.M., Weigert, O.°: Integration of gene mutations in risk prognostication for
patients receiving first-line immunochemotherapy for follicular lymphoma: A retrospective analysis of a
prospective clinical trial and validation in a population-based registry. Lancet Oncol. 16, 1111-1122 (2015)
Paul-Konietzko, K., Thomale, J., Arakawa, H., Iliakis, G.°: DNA ligases I and III support nucleotide excision
repair in DT40 cells with similar efficiency. Photochem. Photobiol. 91, 1173-1180 (2015)
page 141 of 213
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Pfluger, P.T., Kabra, D.G., Aichler, M., Schriever, S.C., Pfuhlmann, K., Casquero García, V., Lehti, M.,
Weber, J., Kutschke, M., Rozman, J., Elrod, J.W., Hevener, A.L., Feuchtinger, A., Hrabě de Angelis, M.,
Walch, A.K., Rollmann, S.M., Aronow, B.J., Müller, T.D., Perez-Tilve, D., Jastroch, M., de Luca, M.,
Molkentin, J.D., Tschöp, M.H.°: Calcineurin links mitochondrial elongation with energy metabolism. Cell
Metab. 22, 838-850 (2015)
Pinto-Teixeira, F.#, Viader-Llargues, O.#, Torres-Mejia, E., Turan, M., Gonzalez-Gualda, E., Pola-Morell, L.,
López-Schier, H.°: Inexhaustible hair-cell regeneration in young and aged zebrafish. Biol. Open 4, 903-909
(2015)
Pockley, A.G., Foulds, G.A., Oughton, J.A., Kerkvliet, N.I., Multhoff, G.°: Immune cell phenotyping using
flow cytometry. Curr. Protoc. Toxicol. 66, 18.8.1-18.8.34 (2015)
Poos, K.#, Smida, J.#, Maugg, D., Eckstein, G.N., Baumhoer, D., Nathrath, M., Korsching, E.°: Genomic
heterogeneity of osteosarcoma - shift from single candidates to functional modules. PLoS ONE 10:e0123082
(2015)
Protzer, U.°: Epigenetic control of HBV by HBx protein-releasing the break? Nat. Rev. Gastroenterol.
Hepatol. 12, 558-559 (2015)
Raffegerst, S.H.°, Steer, B., Hohloch, M., Adler, H.°: Prevention of tumor formation by latent
gammaherpesvirus infection. PLoS ONE 10:e0145678 (2015)
Rancan, C., Schirrmann, L., Hüls, C., Zeidler, R., Moosmann, A.°: Latent membrane protein LMP2A
+
impairs recognition of EBV-infected cells by CD8 T cells. PLoS Pathog. 11:e1004906 (2015)
Ratschiller, T.°, Deutsch, M.A., Calzada-Wack, J., Neff, F., Roesch, C., Guenzinger, R., Lange, R., Krane,
M.: Heterotopic cervical heart transplantation in mice. J. Vis. Exp. 102:e52907 (2015)
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Ribi, S. , Baumhoer, D. , Lee, K. , Edison, Teo, A.S., Madan, B., Zhang, K., Kohlmann, W.K., Yao, F., Lee,
W.H., Hoi, Q., Cai, S.W., Woo, X.Y., Tan, P.L., Jundt, G., Smida, J., Nathrath, M., Sung, W.K., Schiffman,
J.D., Virshup, D.M.°, Hillmer, A.M.°: TP53 intron 1 hotspot rearrangements are specific to sporadic
osteosarcoma and can cause Li-Fraumeni syndrome. Oncotarget 6, 7727-7740 (2015)
Riemer, J.°, Schwarzländer, M., Conrad, M., Herrmann, J.M.: Thiol switches in mitochondria: Operation and
physiological relevance. Biol. Chem. 396, 465-482 (2015)
Ringelhan, M., Reisinger, F., Yuan, D.T., Weber, A., Heikenwälder, M.: Modeling human liver cancer
heterogeneity: Virally induced transgenic models and mouse genetic models of chronic liver inflammation.
Curr. Protoc. Pharmacol. 67, 14.31.1-14.31.17 (2014)
Ringelhan, M., Protzer, U.°: Oncogenic potential of hepatitis B virus encoded proteins. Curr. Opin. Virol. 14,
109-115 (2015)
page 142 of 213
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#
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° corresponding authors
HMGU authors are given in bold letters
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Roeper, B., Heinrich, C., Kehl, V., Rechl, H.P., Specht, K., Woertler, K., Toepfer, A., Molls, M., Kampfer, S.,
von Eisenharth-Rothe, R., Combs, S.E.°: Study of preoperative radiotherapy for sarcomas of the extremities
with intensity-modulation, image-guidance and small safety-margins (PREMISS). BMC Cancer 15:904
(2015)
Rühm, W., Woloschak, G.E., Shore, R.E., Azizova, T.V., Grosche, B., Niwa, O., Akiba, S., Ono, T., Suzuki,
K., Iwasaki, T., Ban, N., Kai, M., Clement, C.H., Bouffler, S., Toma, H., Hamada, N.°: Dose and dose-rate
effects of ionizing radiation: A discussion in the light of radiological protection. Radiat. Environ. Biophys. 54,
379-401 (2015)
Rühm, W.°, Fantuzzi, E., Harrison, R.M., Schuhmacher, H., Vanhavere, F., Alves, J., Bottollier Depois, J.F.,
Fattibene, P., Knezevic, Z., Lopez, M.A., Mayer, S., Miljanić, S., Neumaier, S., Olko, P., Stadtmann, H.,
Tanner, R., Woda, C.: Eurados strategic research agenda: Vision for dosimetry of ionising radiation. Radiat.
Prot. Dosim. 168, 223-234 (2016) [published online 2015]
Sadic, D., Schmidt, K., Groh, S., Kondofersky, I., Ellwart, J.W., Fuchs, C., Theis, F.J., Schotta, G.°: Atrx
promotes heterochromatin formation at retrotransposons. EMBO Rep. 16, 836-850 (2015)
Sakoda, S.°, Meisenberg, O., Tschiersch, J.: Behavior of radon progeny produced in a scintillation cell in
the flow-through condition. Radiat. Meas. 77, 41-45 (2015)
Salomaa, S.°, Averbeck, D., Ottolenghi, A., Sabatier, L., Bouffler, S., Atkinson, M.J., Jourdain, J.R.:
European low-dose radiation risk research strategy: Future of research on biological effects at low doses.
Radiat. Prot. Dosim. 164, 38-41 (2015)
Sambugaro, S., di Ruvo, M., Ambrosio, M.R., Pellegata, N.S., Bellio, M., Guerra, A., Buratto, M., Foschini,
M.P., Tagliati, F., degli Uberti, E.C., Zatelli, M.C.°: Early onset acromegaly associated with a novel deletion in
CDKN1B 5'UTR region. Endocrine 49, 58-64 (2015)
Sass, S.°, Pitea, A.°, Unger, K., Hess, J., Müller, N.S., Theis, F.J.°: MicroRNA-target network inference
and local network enrichment analysis identify two microRNA clusters with distinct functions in head and
neck squamous cell carcinoma. Int. J. Mol. Sci. 16, 30204-30222 (2015)
Saunders, N.R., Dreifuss, J., Dziegielewska, K.M., Johansson, P.A., Habgood, M.D., Møllgård, K., Bauer,
H.: The rights and wrongs of blood-brain barrier permeability studies: A walk through 100 years of history.
Front. Neurosci. 8:404 (2014)
Sautto, G.A., Wisskirchen, K., Clementi, N., Castelli, M., Diotti, R.A., Graf, J., Clementi, M., Burioni, R.,
Protzer, U., Mancini, N.°: Chimeric Antigen Receptor (CAR)-engineered T cells redirected against Hepatitis
C Virus (HCV) E2 glycoprotein. Gut 65, 512-523 (2016) [published online 2015]
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Schemionek, M. , Kharabi Masouleh, B. , Klaile, Y., Krug, U., Hebestreit, K., Schubert, C., Dugas, M.,
Büchner, T., Wörmann, B., Hiddemann, W., Berdel, W.E., Brümmendorf, T.H., Müller-Tidow, C.,
Koschmieder, S.°: Identification of the adapter molecule MTSS1 as a potential oncogene-specific tumor
suppressor in acute myeloid leukemia. PLoS ONE 10:e0125783 (2015)
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Schilling, D., Kühnel, A., Tetzlaff, F., Konrad, S., Multhoff, G.°: NZ28-induced inhibition of HSF1, SP1 and
NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. Cancer
Immunol. Immunother. 64, 599-608 (2015)
Schilling, D., Kühnel, A., Konrad, S., Tetzlaff, F., Bayer, C., Yaglom, J., Multhoff, G.°: Sensitizing tumor
cells to radiation by targeting the heat shock response. Cancer Lett. 360, 294-301 (2015)
Schludi, M.H., May, S., Grässer, F.A., Rentzsch, K., Kremmer, E., Küpper, C., Klopstock, T., Arzberger, T.°,
Edbauer, D.°: Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases
suggests link to transcriptional silencing. Acta Neuropathol. 130, 537-555 (2015)
Schmid, S.C.°, Thümer, L., Schuster, T., Horn, T., Kurtz, F., Slotta-Huspenina, J., Seebach, J., Straub, M.,
Maurer, T., Autenrieth, M., Kübler, H.R., Retz, M., Protzer, U., Gschwend, J.E., Hoffmann, D.: Human
papilloma virus is not detectable in samples of urothelial bladder cancer in a central European population: A
prospective translational study. Infect. Agents Cancer 10:31 (2015)
Schmid, T.E.°, Friedland, W., Greubel, C., Girst, S., Reindl, J., Siebenwirth, C., Ilicic, K., Schmid, E.,
Multhoff, G., Schmitt, E., Kundrát, P., Dollinger, G.: Sub-micrometer 20 MeV protons or 45 MeV lithium
spot irradiation enhances yields of dicentric chromosomes due to clustering of DNA double-strand breaks.
Mutat. Res. - Gen. Tox. Environ. Mutag. 793, 30-40 (2015)
Schmidt, J., Panzilius, E., Bartsch, H.S., Irmler, M., Beckers, J., Kari, V., Linnemann, J., Dragoi, D.,
Hirschi, B., Kloos, U., Sass, S., Theis, F.J., Kahlert, S., Johnsen, S.A., Sotlar, K., Scheel, C.°:
Stem-cell-like properties and epithelial plasticity arise as stable traits after transient Twist1 activation. Cell
Rep. 10, 131-139 (2015)
Schmitt, E.°, Friedland, W., Kundrát, P., Dingfelder, M., Ottolenghi, A.: Cross-section scaling for track
structure simulations of low-energy ions in liquid water. Radiat. Prot. Dosim. 166, 15-18 (2015)
Schmitt, S., Eberhagen, C., Weber, S., Aichler, M., Zischka, H.°: Isolation of mitochondria from cultured
cells and liver tissue biopsies for molecular and biochemical analyses. Methods Mol. Biol. 1295, 87-97
(2015)
Schneider, M., Tigges, B., Meggendorfer, M., Helfer, M., Ziegenhain, C., Brack-Werner, R.°: A new
model for post-integration latency in macroglial cells to study HIV-1 reservoirs of the brain. Aids 29,
1147-1159 (2015)
Schnorfeil, F.M., Lichtenegger, F.S.°, Emmerig, K., Schlueter, M., Neitz, J.S., Draenert, R., Hiddemann,
W., Subklewe, M.: T cells are functionally not impaired in AML: Increased PD-1 expression is only seen at
time of relapse and correlates with a shift towards the memory T cell compartment. J. Hematol. Oncol. 9:93
(2015)
Schöllnberger, H.°, Ozasa, K., Neff, F., Kaiser, J.C.: Cardiovascular disease mortality of a-bomb survivors
and the healthy survivor selection effect. Radiat. Prot. Dosim. 166, 320-323 (2015)
page 144 of 213
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Schraivogel, D., Schindler, S.G., Danner, J., Kremmer, E., Pfaff, J., Hannus, S., Depping, R., Meister, G.°:
Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein
levels. Nucleic Acids Res. 43, 7447-7461 (2015)
Schulz, S., Lichtmannegger, J., Schmitt, S., Leitzinger, C., Eberhagen, C., Einer, C., Kerth, J., Aichler,
M., Zischka, H.°: A protocol for the parallel isolation of intact mitochondria from rat liver, kidney, heart, and
brain. Methods Mol. Biol. 1295, 75-86 (2015)
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Schuster, F.R. , Stanglmaier, M. , Woessmann, W., Winkler, B., Siepermann, M., Meisel, R., Schlegel, P.G.,
Hess, J., Lindhofer, H.G., Borkhardt, A., Buhmann, R.°: Immunotherapy with the trifunctional anti-CD20 x
anti-CD3 antibody FBTA05 (Lymphomun) in paediatric high-risk patients with recurrent CD20-positive B cell
malignancies. Br. J. Haematol. 169, 90-102 (2015)
Seifert, R.#, Flick, M.#, Bönigk, W., Alvarez, L., Trötschel, C., Poetsch, A., Müller, A., Goodwin, N., Pelzer, P.,
Kashikar, N.D., Kremmer, E., Jikeli, J., Timmermann, B., Kuhl, H., Fridman, D., Windler, F., Kaupp, U.B.°,
Strünker, T.°: The CatSper channel controls chemosensation in sea urchin sperm. EMBO J. 34, 379-392
(2015)
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Seleznik, G.M. , Seeger, H. , Bauer, J. , Fu, K., Czerkowicz, J., Papandile, A., Poreci, U., Rabah, D.,
Ranger, A., Cohen, C.D., Lindenmeyer, M., Chen, J., Edenhofer, I., Anders, H.J., Lech, M., Wüthrich, R.P.,
Ruddle, N.H., Moeller, M.J., Kozakowski, N., Regele, H., Browning, J.L., Heikenwälder, M., Segerer, S.°:
The lymphotoxin β receptor is a potential therapeutic target in renal inflammation. Kidney Int. 89, 113–126
(2015)
Selmansberger, M.#, Kaiser, J.C.#°, Hess, J., Güthlin, D., Likhtarov, I., Shpak, V., Tronko, M., Brenner, A.,
Abend, M., Blettner, M., Unger, K., Jacob, P., Zitzelsberger, H.: Dose-dependent expression of CLIP2 in
post-Chernobyl papillary thyroid carcinomas. Carcinogenesis 36, 748-756 (2015)
Selmansberger, M., Braselmann, H., Hess, J., Bogdanova, T., Abend, M., Tronko, M., Brenner, A.,
Zitzelsberger, H., Unger, K.°: Genomic copy number analysis of Chernobyl papillary thyroid carcinoma in
the Ukrainian-American Cohort. Carcinogenesis 36, 1381-1387 (2015)
Semren, N., Welk, V., Korfei, M., Keller, I.E., Fernandez, I.E., Adler, H., Günther, A., Eickelberg, O.,
Meiners, S.°: Regulation of 26S proteasome activity in pulmonary fibrosis. Am. J. Respir. Crit. Care Med.
192, 1089-1101 (2015)
Serth, K., Schuster-Gossler, K., Kremmer, E., Hansen, B.T., Marohn-Köhn, B., Gossler, A.°: O-fucosylation
of DLL3 is required for its function during somitogenesis. PLoS ONE 10:e0123776 (2015)
Sibley, C.R.#, Emmett, W.#, Blazquez, L., Faro, A., Haberman, N., Briese, M., Trabzuni, D., Ryten, M.,
Weale, M.E., Hardy, J., Modic, M., Curk, T., Wilson, S.W., Plagnol, V., Ule, J.: Recursive splicing in long
vertebrate genes. Nature 521, 371-375 (2015)
page 145 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Sievert, W., Trott, K.-R., Azimzadeh, O., Tapio, S., Zitzelsberger, H., Multhoff, G.°: Late proliferating and
inflammatory effects on murine microvascular heart and lung endothelial cells after irradiation. Radiother.
Oncol. 117, 376-381 (2015)
Simonetto, C., Schöllnberger, H., Azizova, T.V., Grigoryeva, E.S., Pikulina, M.V., Eidemüller, M.:
Cerebrovascular diseases in workers at Mayak PA: The difference in radiation risk between incidence and
mortality. PLoS ONE 10:e0125904 (2015)
Singh, S.K., Chen, N.M., Hessmann, E., Siveke, J., Lahmann, M., Singh, G., Voelker, N., Vogt, S., Esposito,
I., Schmidt, A., Brendel, C., Stiewe, T., Gaedcke, J., Merenberger, M., Crawford, H.C., Bamlet, W.R., Zhang,
J.S., Li, X.K., Smyrk, T.C., Billadeau, D.D., Hebrok, M., Neesse, A., Koenig, A., Ellenrieder, V.°: Antithetical
NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity. EMBO J. 34,
517-530 (2015)
Sirko, S., Irmler, M., Gascón, S., Bek, S., Schneider, S., Dimou, L., Obermann, J., de Souza Paiva, D.,
Poirier, F., Beckers, J., Hauck, S.M., Barde, Y.A., Götz, M.°: Astrocyte reactivity after brain injury - the role
of galectins 1 and 3. Glia 63, 2340-2361 (2015)
Sironi, S., Wagner, M., Kuett, A., Drolle, H., Polzer, H., Spiekermann, K., Rieger, C., Fiegl, M.°:
Microenvironmental hypoxia regulates FLT3 expression and biology in AML. Sci. Rep. 5:17550 (2015)
Skiöld, S., Azimzadeh, O., Merl-Pham, J., Näslund, I., Wersäll, P.J., Lidbrink, E.K., Tapio, S.,
Harms-Ringdahl, M., Haghdoost, S.°: Unique proteomic signature for radiation sensitive patients: A
comparative study between normo-sensitive and radiation sensitive breast cancer patients. Mutat. Res.
-Fund. Mol. Mech. Mutag. 776, 128-135 (2015)
Solchenberger, B., Russell, C., Kremmer, E., Haass, C., Schmid, B.°: Granulin knock out zebrafish lack
frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis pathology. PLoS ONE 10:e0118956
(2015)
Song, H., Lee, B., Pyun, D., Guimera, J., Son, Y., Yoon, J., Baek, K., Wurst, W., Jeong, Y.°: Ascl1 and Helt
act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. Dev. Biol. 398,
280-291 (2015)
Specht, H.M., Ahrens, N., Blankenstein, C., Duell, T.H.G., Fietkau, R.J., Gaipl, U.S., Günther, C., Gunther,
S., Habl, G., Hautmann, H., Hautmann, M.G., Huber, R.M., Molls, M.M., Offner, R., Rödel, C.M., Rödel, F.,
Schuetz, M., Combs, S.E., Multhoff, G.°: Heat shock protein 70 (Hsp70) peptide activated Natural Killer
(NK) cells for the treatment of patients with Non-Small Cell Lung Cancer (NSCLC) after radiochemotherapy
(RCTx) - from preclinical studies to a clinical phase II trial. Front. Immunol. 6:162 (2015)
Specht, H.M.°, Neff, T., Reuschel, W., Wagner, F.M., Kampfer, S., Wilkens, J.J., Petry, W., Combs, S.E.:
Paving the road for modern particle therapy - what can we learn from the experience gained with fast neutron
therapy in Munich? Front. Oncol. 5:262 (2015)
page 146 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Spielmann, V.°, Li, W.B., Zankl, M., Oeh, U., Hoeschen, C.: Uncertainty quantification in internal dose
calculations for seven selected radiopharmaceuticals. J. Nucl. Med. 57, 122-128 (2016) [published online
2015]
Srivastava, M., Duan, G., Kershaw, N.J., Athanasopoulos, V., Yeo, J.H., Ose, T., Hu, D., Brown, S.H.,
Jergic, S., Patel, H.R., Pratama, A., Richards, S., Verma, A., Jones, E.Y., Heissmeyer, V., Preiss, T., Dixon,
N.E., Chong, M.M., Babon, J.J., Vinuesa, C.G.°: Roquin binds microRNA-146a and Argonaute2 to regulate
microRNA homeostasis. Nat. Commun. 6:6253 (2015)
#
#
Steinbrück, L. , Gustems, M. , Medele, S., Schulz, T.F., Lutter, D., Hammerschmidt, W.°: K1 and K15 of
Kaposi sarcoma-associated herpes virus are partial functional homologues of latent membrane protein 2A of
Epstein-Barr virus. J. Virol. 89, 7248-7261 (2015)
Strube, C.°, Haake, C., Sager, H., Schorderet Weber, S., Kaminsky, R., Buschbaum, S., Joekel, D., Schicht,
S., Kremmer, E., Korrell, J., Schnieder, T., von Samson-Himmelstjerna, G.: Vaccination with recombinant
paramyosin against the bovine lungworm Dictyocaulus viviparus considerably reduces worm burden and
larvae shedding. Parasit. Vectors 8:119 (2015)
Summerer, I., Unger, K., Braselmann, H., Schuettrumpf, L., Maihoefer, C., Baumeister, P., Kirchner, T.,
Niyazi, M., Sage, E.H., Specht, H.M., Multhoff, G., Mörtl, S., Belka, C., Zitzelsberger, H.°: Circulating
microRNAs as prognostic therapy biomarkers in head and neck cancer patients. Br. J. Cancer 113, 76-82
(2015)
Summerer, I., Hess, J., Pitea, A., Unger, K., Hieber, L., Selmansberger, M., Lauber, K., Zitzelsberger,
H.°: Integrative analysis of the microRNA-mRNA response to radiochemotherapy in primary head and neck
squamous cell carcinoma cells. BMC Genomics 16:654 (2015)
#
#
#
#
Sun, C. , Schattgen, S.A. , Pisitkun, P. , Jorgensen, J.P. , Hilterbrand, A.T., Wang, L.J., West, J.A., Hansen,
K., Horan, K.A., Jakobsen, M.R., O'Hare, P., Adler, H., Sun, R., Ploegh, H.L., Damania, B., Upton, J.W.,
Fitzgerald, K.A., Paludan, S.R.°: Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates
establishment of latent infection. J. Immunol. 194, 1819-1831 (2015)
Sun, N., Fernandez, I.E., Wei, M., Wu, Y., Aichler, M., Eickelberg, O.°, Walch, A.K.°: Pharmacokinetic
and pharmacometabolomic study of pirfenidone in normal mouse tissues using high mass resolution
MALDI-FTICR-mass spectrometry imaging. Histochem. Cell Biol. 145, 201-211 (2016) [published online
2015]
Sweetwyne, M.T., Gruenwald, A., Niranjan, T., Nishinakamura, R., Strobl, L.J., Susztak, K.°: Notch1 and
Notch2 in podocytes play differential roles during diabetic nephropathy development. Diabetes 64,
4099-4111 (2015)
Taverna, E., Götz, M.°, Huttner, A.B.: The cell biology of neurogenesis: Toward an understanding of the
development and evolution of the neocortex. Annu. Rev. Cell Dev. Biol. 30, 465-502 (2014)
page 147 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
#
#
Teiluf, K. , Seidl, C. , Blechert, B., Gaertner, F.C., Gilbertz, K.P., Fernandez, V., Bassermann, F., Endell, J.,
Boxhammer, R., Leclair, S., Vallon, M., Aichler, M., Feuchtinger, A., Bruchertseifer, F., Morgenstern, A.,
Essler, M.°: α-Radioimmunotherapy with 213Bi-anti-CD38 immunoconjugates is effective in a mouse model
of human multiple myeloma. Oncotarget 6, 4692-4703 (2015)
Teles, P.°, Barros, S., Cardoso, S., Facure, A., da Rosa, L.A.R., Santos, M., Pereira, P., Vaz, P., Zankl, M.:
A dosimetric study of prostate brachytherapy using Monte Carlo simulations with a voxel phantom,
measurements and a comparison with a treatment planning procedure. Radiat. Prot. Dosim. 165, 482-487
(2015)
Thiele, F., Tao, S., Zhang, Y., Muschaweckh, A., Zollmann, T., Protzer, U., Abele, R., Drexler, I.°:
+
MVA-infected dendritic cells present CD4 T-cell epitopes by endogenous MHC class II presentation
pathways. J. Virol. 98, 2698-2709 (2015)
Tischer, J.°, Engel, N., Fritsch, S., Prevalsek, D., Hubmann, M., Schulz, C., Zoellner, A.-K., Bücklein, V.L.,
Reibke, R., Mumm, F., Rieger, C.T., Hill, W., Ledderose, G., Stemmler, H.J., Köhnke, T., Jäger, G., Kolb,
H.J., Schmid, C., Moosmann, A., Hausmann, A.: Virus infection in HLA-haploidentical hematopoietic stem
cell transplantation: Incidence in the context of immune recovery in two different transplantation settings.
Ann. Hematol. 94, 1677-1688 (2015)
Toma, M., Wehner, R., Kloss, A., Huebner, L., Fodelianaki, G., Erdmann, K., Fuessel, S., Zastrow, S.,
Meinhardt, M., Seliger, B., Brech, D., Nößner, E., Tonn, T., Schaekel, K., Bornhaeuser, M., Bachmann,
M.P., Wirth, M.P., Baretton, G., Schmitz, M.°: Accumulation of tolerogenic human 6-sulfo LacNAc dendritic
cells in renal cell carcinoma is associated with poor prognosis. OncoImmunology 4:e1008342 (2015)
Träber, S.C.°, Li, W.B.°, Höllriegl, V., Nebelung, K., Michalke, B., Rühm, W., Oeh, U.: Calculation of
internal dose from ingested soil-derived uranium in humans: Application of a new method. Radiat. Environ.
Biophys. 54, 265-272 (2015)
Truong, D.J.J., Kühner, K., Kühn, R., Werfel, S., Engelhardt, S., Wurst, W.°, Ortiz, O.°: Development of an
intein-mediated split-Cas9 system for gene therapy. Nucleic Acids Res. 43, 6450-6458 (2015)
Uda, N.R.°, Seibert, V., Stenner-Liewen, F., Müller, P., Herzig, P., Gondi, G., Zeidler, R., van Dijk, M.,
Zippelius, A., Renner, C.°: Esterase activity of carbonic anhydrases serves as surrogate for selecting
antibodies blocking hydratase activity. J. Enzyme Inhib. Med. Chem. 30, 955-960 (2015)
Uzbas, F., May, I.D., Parisi, A.M., Thompson, S.K., Kaya, A., Perkins, A.D., Memili, E.°: Molecular
physiognomies and applications of adipose-derived stem cells. Stem Cell Rev. Rep. 11, 298-308 (2014)
van Berkel, A., Upendrao, J., Lenders, J., Pellegata, N.S., Kusters, B., Piscaer, I., Hermus, A.R., Plantinga,
T.S., Langenhuijsen, H., Vriens, D., Janssen, M., Gotthardt, M., Timmers, H.°: Semi-quantitative
123
I-metaiodobenzylguanidine scintigraphy to distinguish pheochromocytoma and paraganglioma from
physiological adrenal uptake and its correlation with genotype-dependent expression of catecholamine
transporters. J. Nucl. Med. 56, 839-846 (2015)
page 148 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
van Nierop, G.P., Mautner, J., Mitterreiter, J.G., Hintzen, R.Q., Verjans, G.M.°: Intrathecal CD8 T-cells of
multiple sclerosis patients recognize lytic Epstein-Barr virus proteins. Mult. Scler. J. 22, 279-291 (2016)
[published online 2015]
Vassena, L., Giuliani, E., Koppensteiner, H., Bolduan, S., Schindler, M., Doria, M.°: HIV-1 NEF and VPU
interfere with L-selectin (CD62L) cell surface expression to inhibit adhesion and signaling in infected CD4+ t
lymphocytes. J. Virol. 89, 5687-5700 (2015)
Velikova, V.B., Müller, C., Ghirardo, A., Rock, T., Aichler, M., Walch, A.K., Schmitt-Kopplin, P.,
Schnitzler, J.-P.°: Knocking down of isoprene emission modifies the lipid matrix of thylakoid membranes
and influences the chloroplast ultrastructure in poplar. Plant Physiol. 168, 859-870 (2015)
Vick, B., Rothenberg, M., Sandhöfer, N., Carlet, M., Finkenzeller, C., Krupka, C., Grunert, M., Trumpp,
A., Corbacioglu, S., Ebinger, M., Andre, M.C., Hiddemann, W., Schneider, S., Subklewe, M., Metzeler,
K.H., Spiekermann, K., Jeremias, I.°: An advanced preclinical mouse model for acute myeloid leukemia
using patients' cells of various genetic subgroups and in vivo bioluminescence imaging. PLoS ONE
10:e0120925 (2015)
Viganò, F., Dimou, L.: The heterogeneous nature of NG2-glia. Brain Res. (2015)
Vincendeau, M., Krappmann, D., Hadian, K.°: In vitro detection of NEMO-ubiquitin binding using DELFIA
and microscale thermophoresis assays. Methods Mol. Biol. 1280, 311-320 (2015)
Vincendeau, M., Göttesdorfer, I., Schreml, J., Wetie, A., Mayer, J., Greenwood, A.D., Helfer, M., Kramer,
S., Seifarth, W., Hadian, K., Brack-Werner, R., Leib-Mösch, C.°: Modulation of Human Endogenous
Retrovirus (HERV) transcription during persistent and de novo HIV-1 infection. Retrovirol. 12:27 (2015)
Vogl, A.M.#, Brockmann, M.M.#, Giusti, S.A., Maccarrone, G., Vercelli, C.A., Bauder, C.A., Richter, J.S.,
Roselli, F., Hafner, A.S., Dedic, N., Wotjak, C.T., Vogt Weisenhorn, D.M., Choquet, D., Turck, C.W., Stein,
V., Deussing, J.M., Refojo, D.°: Neddylation inhibition impairs spine development, destabilizes synapses and
deteriorates cognition. Nat. Neurosci. 18, 239-251 (2015)
Voss, K., Forne, I., Descostes, N., Hintermair, C., Schüller, R., Maqbool, M.A., Heidemann, M., Flatley,
A., Imhof, A., Gut, M., Gut, I., Kremmer, E., Andrau, J.C., Eick, D.: Site-specific methylation and acetylation
of lysine residues in the C-terminal domain (CTD) of RNA polymerase II. Transcription 13, 91-101 (2015)
Vrba, T.°, Broggio, D., Caldeira, M., Capello, K., Fantínová, K., Franck, D., Gómez-Ros, J.M., Hunt, J.,
Kinase, S., Leone, D., Lombardo, P.A., Manohari, M., Marzocchi, O., Moraleda, M., Nogueira, P., Ośko, J.,
Arron, S., Suhl, S., Takahashi, M., Teles, P., Tremblay, M., Tymińska, K., Lopez, M.A., Tanner, R.:
EURADOS intercomparison exercise on MC modelling for the in-vivo monitoring of AM-241 in skull
phantoms (Part II and III). Radiat. Phys. Chem. 113, 59-71 (2015)
Vukicevic, V., Rubin de Celis, M.F., Pellegata, N.S., Bornstein, S.R., Androutsellis-Theotokis, A.,
Ehrhart-Bornstein, M.°: Adrenomedullary progenitor cells: Isolation and characterization of a multi-potent
progenitor cell population. Mol. Cell. Endocrinol. 408, 178-184 (2015)
page 149 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Warth, S.C., Höfig, K.P., Hiekel, A., Schallenberg, S., Jovanovic, K., Klein, L., Kretschmer, K., Ansel, K.M.,
Heissmeyer, V.°: Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote
regulatory T-cell differentiation. EMBO J. 34, 1195-1213 (2015)
Washkowitz, A.J., Schall, C., Zhang, K.L., Wurst, W., Floß, T., Mager, J., Papaioannou, V.E.°: Mga is
essential for the survival of pluripotent cells during peri-implantation development. Development 142, 31-40
(2015)
Weber, A., O'Connor, T., Heikenwälder, M.°: Next generation of preclinical liver cancer models. Clin. Cancer
Res. 21, 4254-4256 (2015)
Weber, J.#, Öllinger, R.#, Friedrich, M., Ehmer, U., Barenboim, M., Steiger, K., Heid, I.M., Mueller, S.,
Maresch, R., Engleitner, T., Gross, N., Geumann, U., Fu, B., Segler, A., Yuan, D.T., Lange, S., Strong, A.,
de la Rosa, J., Esposito, I., Liu, P., Cadiñanos, J., Vassiliou, G.S., Schmid, R.M., Schneider, G., Unger, K.,
Yang, F., Braren, R., Heikenwälder, M., Varela, I., Saur, D., Bradley, A., Rad, R.°: CRISPR/Cas9 somatic
multiplex-mutagenesis for high-throughput functional cancer genomics in mice. Proc. Natl. Acad. Sci. U.S.A.
112, 13982-13987 (2015)
Weber, S., Salabei, J.K., Möller, G., Kremmer, E., Bhatnagar, A., Adamski, J.°, Barski, O.A.°: Aldo-Keto
Reductase 1B15 (AKR1B15): A mitochondrial human aldo-keto reductase with activity toward steroids and
3-keto-acyl-CoA conjugates. J. Biol. Chem. 290, 6531-6545 (2015)
Wester, H.J.°, Keller, U., Schottelius, M., Beer, A., Philipp-Abbrederis, K., Hoffmann, F., Simecek, J.,
Gerngross, C., Lassmann, M., Herrmann, K., Pellegata, N.S., Rudelius, M., Kessler, H., Schwaiger, M.:
Disclosing the CXCR4 expression in lymphoproliferative diseases by targeted molecular imaging.
Theranostics 5, 618-630 (2015)
Wiedemann, T., Pellegata, N.S.°: Animal models of multiple endocrine neoplasia. Mol. Cell. Endocrinol.
421, 49-59 (2015)
Wiedemann, T., Bielohuby, M., Müller, T.D., Bidlingmaier, M., Pellegata, N.S.°: Obesity in MENX rats is
accompanied by high circulating levels of ghrelin and improved insulin sensitivity. Diabetes 65, 406-420
(2015)
Willem, M.°, Tahirovic, S., Busche, M.A., Ovsepian, S.V., Chafai, M., Kootar, S., Hornburg, D., Evans, L.D.,
Moore, S., Daria, A., Hampel, H., Müller, V., Giudici, C., Nuscher, B., Wenninger-Weinzierl, A., Kremmer, E.,
Heneka, M.T., Thal, D.R., Giedraitis, V., Lannfelt, L., Müller, U., Livesey, F.J., Meissner, F., Herms, J.,
Konnerth, A., Marie, H., Haass, C.°: η-secretase processing of APP inhibits neuronal activity in the
hippocampus. Nature 526, 443-447 (2015)
Wimmer, P.#, Berscheminski, J.#, Blanchette, P., Groitl, P., Branton, P.E., Hay, R.T., Dobner, T., Schreiner,
S.°: PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally
inhibiting the tumor-suppressor p53. Oncogene 35, 69–82 (2016) [published online 2015]
page 150 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Wimmer, P., Schreiner, S.°: Viral mimicry to usurp ubiquitin and sumo host pathways. Viruses 7, 4854-4877
(2015)
Wittmaack, K.°: Attenuation length in ion-induced kinetic electron emission: A key to an understanding of
angular-dependent yields. Phys. Rev. B Condens. Matter 91:115434 (2015)
Wohlleben, G., Scherzad, A., Guettler, A., Vordermark, D., Kuger, S., Flentje, M., Polat, B.°: Influence of
hypoxia and irradiation on osteopontin expression in head and neck cancer and glioblastoma cell lines.
Radiat. Oncol. 10:167 (2015)
Xia, Y., Stadler, D., Lucifora, J., Reisinger, F., Webb, D., Hösel, M., Michler, T., Wisskirchen, K., Cheng,
X., Zhang, K., Chou, W.M., Wettengel, J.M., Malo, A., Bohne, F., Hoffmann, D., Eyer, F., Thimme, R.,
Falk, C.S., Thasler, W.E., Heikenwälder, M., Protzer, U.°: Interferon-γ and tumor necrosis factor-α
produced by T cells reduce the HBV persistence form, cccDNA, without cytolysis. Gastroenterology 150,
194-205 (2015)
Xiao, Y., Faucherre, A., Pola-Morell, L., Heddleston, J.M., Liu, T.L., Chew, T.L., Sato, F., Sehara-Fujisawa,
A., Kawakami, K., López-Schier, H.°: High-resolution live imaging reveals axon-glia interactions during
peripheral nerve injury and repair in zebrafish. Dis. Model. Mech. 8, 553-564 (2015)
Xiao, Y., Tian, W., López-Schier, H.°: Optogenetic stimulation of neuronal repair. Curr. Biol. 25, R1-R3
(2015)
Xie, W.Z.°, Friedland, W., Li, W.B.°, Li, C.Y., Oeh, U., Qiu, R., Li, J.L., Hoeschen, C.: Simulation on the
molecular radiosensitization effect of gold nanoparticles in cells irradiated by X-rays. Phys. Med. Biol. 60,
6195-6212 (2015)
Yentrapalli, R., Azimzadeh, O., Kraemer, A., Malinowsky, K., Sarioglu, H., Becker, K.F., Atkinson, M.J.,
Mörtl, S., Tapio, S.°: Quantitative and integrated proteome and microRNA analysis of endothelial replicative
senescence. J. Proteomics 126, 12-23 (2015)
#
#
Yu, X. , Ilecka, M. , Bartlett, E.J., Schneidt, V., Bhat, R., Mautner, J., Feederle, R., Delecluse, H.J.°:
+
Antigen-armed antibodies targeting B lymphoma cells effectively activate antigen-specific CD4 T cells.
Blood 125, 1601-1610 (2015)
Zacarias-Cabeza, J.#, Belhocine, M.#, Vanhille, L., Cauchy, P., Koch, F., Pekowska, A., Fenouil, R., Bergon,
A., Gut, M., Gut, I., Eick, D., Imbert, J., Ferrier, P.°, Andrau, J.C.°, Spicuglia, S.°: Transcription-dependent
generation of a specialized chromatin structure at the TCRβ locus. J. Immunol. 194, 3432-3443 (2015)
Zarzycka, B., Seijkens, T., Nabuurs, S.B., Ritschel, T., Grommes, J., Soehnlein, O., Schrijver, R.S., van Tiel,
C.M., Hackeng, T.M., Weber, C., Giehler, F., Kieser, A., Lutgens, E., Vriend, G., Nicolaes, G.A.F.°:
Discovery of small molecule CD40-TRAF6 inhibitors. J. Chem. Inf. Model. 55, 294-307 (2015)
Zhang, Y., Lin, S., Karakatsani, A., Rüegg, M.A., Kröger, S.°: Differential regulation of AChR clustering in the
polar and equatorial region of murine muscle spindles. Eur. J. Neurosci. 41, 69-78 (2015)
page 151 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
Mechanisms of Genetic and Environmental Influences on Health and Disease
Zhang, Y., Wesolowski, M., Karakatsani, A., Witzemann, V., Kröger, S.: Formation of cholinergic
synapse-like specializations at developing murine muscle spindles. Dev. Biol. 393, 227-235 (2014)
Zhao, Y.°, Zhao, L., Ischenko, I., Bao, Q., Schwarz, B.E., Nieß, H., Wang, Y., Renner, A., Mysliwietz, J.,
Jauch, K.-W., Nelson, P.J., Ellwart, J.W., Bruns, C.J., Camaj, P.°: Antisense inhibition of microRNA-21 and
microRNA-221 in tumor-initiating stem-like cells modulates tumorigenesis, metastasis, and chemotherapy
resistance in pancreatic cancer. Target. Oncol. 10, 535-548 (2015)
Zoellner, A.-K.°, Bayerl, S., Hutter, G., Zimmermann, Y., Hiddemann, W., Dreyling, M.: Temsirolimus
inhibits cell growth in combination with inhibitors of the B-cell receptor pathway. Leuk. Lymphoma 56,
3393-3400 (2015)
Zöllner, S.°, Sokolnikov, M.E., Eidemüller, M.: Beyond two-stage models for lung carcinogenesis in the
Mayak workers: Implications for Plutonium risk. PLoS ONE 10:e0126238 (2015)
®
Zugmaier, G., Klinger, M.°, Schmidt, M., Subklewe, M.: Clinical overview of anti-CD19 BiTE and ex vivo
®
data from anti-CD33 BiTE as examples for retargeting T cells in hematologic malignancies. Mol. Immunol.
67, 58–66 (2015)
page 152 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Abdelaziz, A.°, Sushko, Y., Novotarskyi, S., Koerner, R., Brandmaier, S., Tetko, I.V.: Using online tool
(iPrior) for modeling ToxCast™ assays towards prioritization of animal toxicity testing. Comb. Chem. High
Throughput Screen. 18, 420-438 (2015)
Aichler, M., Walch, A.K.°: MALDI Imaging mass spectrometry: Current frontiers and perspectives in
pathology research and practice. Lab. Invest. 95, 422-431 (2015)
Aichler, M., Huber, K., Schilling, F., Lohöfer, F., Kosanke, K., Meier, R., Rummeny, E.J., Walch, A.K.°,
Wildgruber, M.: Spatially resolved quantification of Gadolinium(III)-based magnetic resonance agents in
tissue by MALDI imaging mass spectrometry after in vivo MRI. Angew. Chem.-Int. Edit. 54, 4279-4283
(2015)
Almstätter, I., Mykhaylyk, O., Settles, M., Altomonte, J., Aichler, M., Walch, A.K., Rummeny, E.J., Ebert, O.,
Plank, C., Braren, R.°: Characterization of magnetic viral complexes for targeted delivery in oncology.
Theranostics 5, 667-685 (2015)
Ameling, S., Kacprowski, T., Chilukoti, R.K., Malsch, C., Liebscher, V., Suhre, K., Pietzner, M., Friedrich, N.,
Homuth, G., Hammer, E., Völker, U.°: Associations of circulating plasma microRNAs with age, body mass
index and sex in a population-based study. BMC Med. Genomics 8:61 (2015)
Andreetto, E.#, Malideli, E.#, Yan, L.M.#, Kracklauer, M., Farbiarz, K., Tatarek-Nossol, M., Rammes, G.,
Prade, E., Neumüller, T., Caporale, A., Spanopoulou, A., Bakou, M., Reif, B., Kapurniotu, A.°: A
hot-segment-based approach for the design of cross-amyloid interaction surface mimics as inhibitors of
amyloid self-assembly. Angew. Chem.-Int. Edit. 54, 13095-13100 (2015)
Anlauf, M., Hein, L., Hense, H.W., Köbberling, J., Lasek, R., Leidl, R., Schöne-Seifert, B.: Complementary
and alternative drug therapy versus science-oriented medicine. GMS Ger. Med. Sci. 13:Doc05 (2015)
Anosova, I., Melnik, S., Tripsianes, K., Kateb, F., Grummt, I., Sattler, M.°: A novel RNA binding surface of
the TAM domain of TIP5/BAZ2A mediates epigenetic regulation of rRNA genes. Nucleic Acids Res. 43,
5208-5220 (2015)
Anton, G.°, Wilson, R.K., Yu, Z., Prehn, C., Zukunft, S., Adamski, J., Heier, M., Meisinger, C.,
Römisch-Margl, W., Wang-Sattler, R., Hveem, K., Wolfenbuttel, B.H.R., Peters, A., Kastenmüller, G.,
Waldenberger, M.: Pre-analytical sample quality: Metabolite ratios as an intrinsic marker for prolonged room
temperature exposure of serum samples. PLoS ONE 10:e0121495 (2015)
Arloth, J., Bogdan, R., Weber, P., Frishman, G., Menke, A., Wagner, K.V., Balsevich, G., Schmidt, M.V.,
Karbalai, N., Czamara, D., Altmann, A., Trümbach, D., Wurst, W., Mehta, D., Uhr, M., Klengel, T., Erhardt,
A., Carey, C.E., Conley, E.D., Ruepp, A., Müller-Myhsok, B., Hariri, A.R., Binder, E.B.°: Genetic differences
in the immediate transcriptome response to stress predict risk-related brain function and psychiatric
disorders. Neuron 86, 1189-1202 (2015)
Asami, S., Porter, J.R., Lange, O.F., Reif, B.°: Access to Cα backbone dynamics of biological solids by
T1 relaxation and molecular dynamics simulation. J. Am. Chem. Soc. 137, 1094-1100 (2015)
13
C
page 153 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Assmann, W.°, Kellnberger, S., Reinhardt, S., Lehrack, S., Edlich, A., Thirolf, P.G., Moser, M., Dollinger, G.,
Omar, M., Ntziachristos, V., Parodi, K.: Ionoacoustic characterization of the proton Bragg peak with
submillimeter accuracy. Med. Phys. 42, 567-574 (2015)
Attia, A.B.E., Balasundaram, G., Driessen, W.H.P., Ntziachristos, V., Olivo, M.°: Phthalocyanine
photosensitizers as contrast agents for in vivo photoacoustic tumor imaging. Biomed. Opt. Express 6,
591-598 (2015)
Azimzadeh, O.°, Sievert, W., Sarioglu, H., Merl-Pham, J., Yentrapalli, R., Bakshi, M.V., Janik, D.,
Ueffing, M., Atkinson, M.J., Multhoff, G., Tapio, S.: Integrative proteomics and targeted transcriptomics
analyses in cardiac endothelial cells unravel mechanisms of long-term radiation-induced vascular
dysfunction. J. Proteome Res. 14, 1203-1219 (2015)
Balasundaram, G.#, Ho, C.J.H.#, Li, K., Driessen, W.H.P., Dinish, U.S., Wong, C.L., Ntziachristos, V., Liu,
B., Olivo, M.C.D.°: Molecular photoacoustic imaging of breast cancer using an actively targeted conjugated
polymer. Int. J. Nanomed. 10, 387-397 (2015)
Barbosa, J.S., Sanchez-Gonzalez, R., di Giaimo, R., Baumgart, E.V., Theis, F.J., Götz, M., Ninkovic,
J.°: Live imaging of adult neural stem cell behavior in the intact and injured zebrafish brain. Science 348,
789-793 (2015)
Barjaktarovic, Z., Kempf, S.J., Sriharshan, A., Merl-Pham, J., Atkinson, M.J., Tapio, S.°: Ionizing
radiation induces immediate protein acetylation changes in human cardiac microvascular endothelial cells. J.
Radiat. Res. 56, 623-632 (2015)
Barnsley, M.F.°, Massopust, P.°: Bilinear fractal interpolation and box dimension. J. Approx. Theory 192,
362-378 (2015)
Barrios, C.°, Zierer, J., Gudelj, I., Stambuk, J., Ugrina, I., Rodriguez, E., Soler, M.J., Pavić, T., Simurina, M.,
Keser, T., Pučić-Baković, M., Mangino, M., Pascual, J., Spector, T.D., Lauc, G., Menni, C.: Glycosylation
profile of IgG in moderate kidney dysfunction. J. Am. Soc. Nephrol. 27, 933-941 (2015)
#
#
Bartel, J. , Krumsiek, J. , Schramm, K., Adamski, J., Gieger, C., Herder, C., Carstensen, M., Peters, A.,
Rathmann, W., Roden, M., Strauch, K., Suhre, K., Kastenmüller, G., Prokisch, H., Theis, F.J.°: The
human blood metabolome-transcriptome interface. PLoS Genet. 11:e1005274 (2015)
Bauer, L., Takacs, A., Slotta-Huspenina, J., Langer, R., Becker, K., Novotny, A., Ott, K., Walch, A.K.,
Hapfelmeier, A., Keller, G.°: Clinical significance of NOTCH1 and NOTCH2 expression in gastric carcinomas:
An immunohistochemical study. Front. Oncol. 5:94 (2015)
Baust, M.°, Demaret, L.°, Storath, M.°, Navab, N.°, Weinmann, A.°: Total variation regularization of shape
signals. Proc. IEEE Inst. Electr. Electron. Eng., 2075-2083 (2015)
Becker, C.°, Holle, R., Stollenwerk, B.: The excess health care costs of KardioPro, an integrated care
program for coronary heart disease prevention. Health Policy 119, 778-786 (2015)
page 154 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
#
#
Becker, L. , Kling, E. , Schiller, E., Zeh, R., Schrewe, A., Hölter, S.M., Mossbrugger, I., Calzada-Wack,
J., Strecker, V., Wittig, I., Dumitru, I., Wenz, T., Bender, A., Aichler, M., Janik, D., Neff, F., Walch, A.K.,
Quintanilla-Fend, L., Floß, T., Bekeredjian, R., Gailus-Durner, V., Fuchs, H., Wurst, W., Meitinger, T.,
Prokisch, H., Hrabě de Angelis, M., Klopstock, T.°: MTO1-deficient mouse model mirrors the human
phenotype showing complex I defect and cardiomyopathy. PLoS ONE 9:e114918 (2014)
Benmerah, A., Durand, B., Giles, R.H., Harris, T., Kohl, L., Laclef, C., Meilhac, S.M., Mitchison, H.M.,
Pedersen, L.B., Roepman, R., Swoboda, P., Ueffing, M., Bastin, P.°: The more we know, the more we have
to discover: An exciting future for understanding cilia and ciliopathies. Cilia 4:5 (2015)
Bergmann, R.°, Laus, F.°, Steidl, G.°, Weinmann, A.°: Second order differences of cyclic data and
applications in variational denoising. SIAM J. Imaging Sci. 7, 2916-2953 (2014)
Bézière, N.°, Ntziachristos, V.: Optoacoustic imaging of naphthalocyanine: Potential for contrast
enhancement and therapy monitoring. J. Nucl. Med. 56, 323-328 (2015)
Bi, Z., Merl-Pham, J., Uehlein, N., Zimmer, I., Mühlhans, S., Aichler, M., Walch, A.K., Kaldenhoff, R.,
Palme, K., Schnitzler, J.-P., Block, K.°: RNAi-mediated downregulation of poplar Plasma membrane
Intrinsic Proteins (PIPs) changes plasma membrane proteome composition and affects leaf physiology. J.
Proteomics 128, 321-332 (2015)
Bonifacio, E., Ziegler, A.-G., Klingensmith, G., Schober, E., Bingley, P.J., Rottenkolber, M., Theil, A.,
Eugster, A., Puff, R., Peplow, C., Buettner, F., Lange, K., Hasford, J., Achenbach, P.°: Effects of high-dose
oral insulin on immune responses in children at high risk for type 1 diabetes: The Pre-POINT randomized
clinical trial. JAMA 313, 1541-1549 (2015)
Bozorgmehr, K.°, San Sebastian, M., Brenner, H., Razum, O., Maier, W., Saum, K.U., Holleczek, B., Miksch,
A., Szecsenyi, J.: Analysing horizontal equity in enrolment in Disease Management Programmes for
coronary heart disease in Germany 2008–2010. Int. J. Equity Health 14:28 (2015)
Bozorgmehr, K.°, Maier, W., Brenner, H., Saum, K.U., Stock, C., Miksch, A., Holleczek, B., Szecsenyi, J.,
Razum, O.: Social disparities in disease management programmes for coronary heart disease in Germany: A
cross-classified multilevel analysis. J. Epidemiol. Community Health 69, 1091-1101 (2015)
Brandes, A., Sinner, M.F., Kääb, S., Rogowski, W.H.°: Early decision-analytic modeling - a case study on
vascular closure devices. BMC Health Serv. Res. 15:486 (2015)
Breuer, D., Friedrich, C., Moehlmann, C., Dragan, G.-C.: Das miniaturisierte Probenahmesystem
GGP-Minizur gleichzeitigen Erfassung von Dampf-Tröpfchen-Gemischen schwerflüchtiger Verbindungen :
Ergebnisse von Labor- und Praxismessungen. Gefahrstoffe Reinhalt. Luft 75, 390-394 (2015)
#
#
Breuer, D. °, Dragan, G.-C. , Friedrich, C., Möhlmann, C., Zimmermann, R.: Development and field testing
of a miniaturized sampling system for simultaneous sampling of vapours and droplets. Environ. Sci. Process
Impacts 17, 278-287 (2015)
page 155 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Bruns, E.A., Krapf, M., Orasche, J., Huang, Y., Zimmermann, R., Drinovec, L., Močnik, G., El Haddad, I.,
Slowik, J.G., Dommen, J., Baltensperger, U.R.S., Prevot, A.S.H.°: Characterization of primary and
secondary wood combustion products generated under different burner loads. Atmos. Chem. Phys. 15,
2825-2841 (2015)
Buchner, S., Schlundt, A., Lassak, J., Sattler, M., Jung, K.°: Structural and functional analysis of the signal
transducing linker in the pH-responsive one component system CadC of Escherichia coli. J. Mol. Biol. 427,
2548-2561 (2015)
#
#
Buck, A. , Ly, A. , Balluff, B., Sun, N., Gorzolka, K., Feuchtinger, A., Janssen, K.P., Kuppen, P.J., van de
Velde, C.J., Weirich, G., Erlmeier, F., Langer, R., Aubele, M., Zitzelsberger, H., Aichler, M., Walch, A.K.°:
High-resolution MALDI-FT-ICR MS imaging for the analysis of metabolites from formalin-fixed
paraffin-embedded clinical tissue samples. J. Pathol. 237, 123–132 (2015)
Buettner, F.#, Natarajan, K.N.#, Casale, F.P., Proserpio, V., Scialdone, A., Theis, F.J., Teichmann, S.A.,
Marioni, J.C.°, Stegle, O.°: Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing
data reveals hidden subpopulations of cells. Nat. Biotechnol. 33, 155-160 (2015)
Butzke, B., Oduncu, F.S., Severin, F., Pfeufer, A., Heinemann, V., Giessen-Jung, C., Stollenwerk, B.,
Rogowski, W.H.°: The cost-effectiveness of UGT1A1 genotyping before colorectal cancer treatment with
irinotecan from the perspective of the German statutory health insurance. Acta Oncol. 55, 318-328 (2016)
[published online 2015]
Calzolari, F., Michel, J., Baumgart, E.V., Theis, F.J., Götz, M.°, Ninkovic, J.°: Fast clonal expansion and
limited neural stem cell self-renewal in the adult subependymal zone. Nat. Neurosci. 18, 490-492 (2015)
Chaki, M., Shekariesfahlan, A., Ageeva, A., Mengel, A., von Toerne, C., Durner, J., Lindermayr, C.°:
Identification of nuclear target proteins for S-nitrosylation in pathogen-treated Arabidopsis thaliana cell
cultures. Plant Sci. 238, 115-126 (2015)
Chekkoury, A., Gateau, J., Driessen, W.H.P., Symvoulidis, P., Bézière, N., Feuchtinger, A., Walch,
A.K., Ntziachristos, V.°: Optical mesoscopy without the scatter: Broadband multispectral optoacoustic
mesoscopy. Biomed. Opt. Express 6, 3134-3148 (2015)
Chevelkov, V.°, Xiang, S., Giller, K., Becker, S.T., Lange, A.D., Reif, B.: Perspectives for sensitivity
enhancement in proton-detected solid-state NMR of highly deuterated proteins by preserving water
magnetization. J. Biomol. NMR 61, 151-160 (2015)
Choi, S.S., Mandelis, A.°, Guo, X., Lashkari, B., Kellnberger, S., Ntziachristos, V.: Wavelength-Modulated
Differential Photoacoustic Spectroscopy (WM-DPAS) for noninvasive early cancer detection and tissue
hypoxia monitoring. J. Biophotonics 9, 388-395 (2016) [published online 2015]
Christensen, O., Forster, B., Massopust, P.°: Directional time-frequency analysis via continuous frames.
Bull. Austral. Math. Soc. 92, 268-281 (2015)
page 156 of 213
31.12.2015
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#
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° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Chromikova, V., Mader, A., Hofbauer, S., Göbl, C., Madl, T., Gach, J.S., Bauernfried, S., Furtmüller, P.G.,
Forthal, D.N., Mach, L., Obinger, C.°, Kunert, R.°: Introduction of germline residues improves the stability of
anti-HIV mAb 2G12-IgM. Biochim. Biophys. Acta-Proteins Proteom. 1854, 1536–1544 (2015)
Chronakova, A.°, Schloter-Hai, B., Radl, V., Endesfelder, D., Quince, C., Elhottova, D., Simek, M.,
Schloter, M.: Response of archaeal and bacterial soil communities to changes associated with outdoor
cattle overwintering. PLoS ONE 10:e0135627 (2015)
Conlon, T.M., Bartel, J., Ballweg, K., Günter, S., Prehn, C., Krumsiek, J., Meiners, S., Theis, F.J.,
Adamski, J., Eickelberg, O., Yildirim, A.Ö.°: Metabolomics screening identifies reduced L-carnitine to be
associated with progressive emphysema. Clin. Sci. 130, 273-287 (2015)
Crevenna, A.H.°, Arciniega, M., Dupont, A., Mizuno, N., Kowalska, K., Lange, O.F., Wedlich-Soeldner, R.,
Lamb, D.C.: Side-binding proteins modulate actin filament dynamics. eLife 4, DOI: 10.1101/008128 (2015)
Cruz Perez, C., Lauri, A., Symvoulidis, P., Cappetta, M., Erdmann, A., Westmeyer, G.G.°: Calcium
neuroimaging in behaving zebrafish larvae using a turn-key light field camera. J. Biomed. Opt. 20:96009
(2015)
Cui, H., Hense, B.A., Müller, J., Schröder, P.°: Short term uptake and transport process for metformin in
roots of Phragmites australis and Typha latifolia. Chemosphere 134, 307-312 (2015)
Dames, S.A.°: One short cysteine-rich sequence pattern - two different disulfide-bonded structures - a
molecular dynamics simulation study. J. Pept. Sci. 21, 480-494 (2015)
de Boer, E., Harlaar, N.J., Taruttis, A., Nagengast, W.B., Rosenthal, E.L., Ntziachristos, V., van Dam,
G.M.°: Optical innovations in surgery. Br. J. Surg. 102, e56-e72 (2015)
de Cicco, M., Abd Rahim, M.S., Dames, S.A.°: Regulation of the target of rapamycin and other
phosphatidylinositol 3-kinase-related kinases by membrane targeting. Membranes 5, 553-575 (2015)
de Wit, G.A.°, Over, E.A., Schmid, B.V., van Bergen, J.E., van den Broek, I.V., van der Sande, M.A., Welte,
R., Op de Coul, E.L., Kretzschmar, M.E.: Chlamydia screening is not cost-effective at low participation rates:
Evidence from a repeated register-based implementation study in the Netherlands. Sex. Transm. Dis. 91,
423-429 (2015)
Dean-Ben, X.L., Ford, S.J., Razansky, D.°: High-frame rate four dimensional optoacoustic tomography
enables visualization of cardiovascular dynamics and mouse heart perfusion. Sci. Rep. 5:10133 (2015)
Dean-Ben, X.L.#, Estrada, H.#, Ozbek, A., Razansky, D.°: Influence of the absorber dimensions on
wavefront shaping based on volumetric optoacoustic feedback. Opt. Lett. 40, 5395-5398 (2015)
Dean-Ben, X.L., Stiel, A.C., Jiang, Y., Ntziachristos, V., Westmeyer, G.G., Razansky, D.°: Light fluence
normalization in turbid tissues via temporally unmixed multispectral optoacoustic tomography. Opt. Lett. 40,
4691-4694 (2015)
page 157 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Dean-Ben, X.L., Pang, G.A., de Espinosa, F.M., Razansky, D.°: Non-contact optoacoustic imaging with
focused air-coupled transducers. Appl. Phys. Lett. 107:051105 (2015)
Dean-Ben, X.L.#, Estrada, H.#, Razansky, D.°: Shaping volumetric light distribution through turbid media
using real-time three-dimensional opto-acoustic feedback. Opt. Lett. 40, 443-446 (2015)
Dean-Ben, X.L., Fehm, T.F., Gostic, M., Razansky, D.°: Volumetric hand-held optoacoustic angiography as
a tool for real-time screening of dense breast. J. Biophotonics 9, 253-259 (2016) [published online 2015]
Demaret, L.°, Iske, A.°: Optimal N-term approximation by linear splines over anisotropic Delaunay
triangulations. Math. Comput. 84, 1241-1264 (2015)
Derntl, A., Plant, C.°: Clustering techniques for neuroimaging applications. WIREs Data Mining Knowl.
Discov. 6, 22–36 (2015)
Derntl, A., Plant, C., Gruber, P., Wegener, S., Bauer, J.S., Menze, B.: Stroke lesion segmentation using a
probabilistic atlas of cerebral vascular territories. Lecture Notes Comp. Sci. (2015)
Diab, J., Streibel, T., Cavalli, F., Lee, S.C., Saathoff, H., Mamakos, A., Chow, J.C., Chen, L.W.A., Watson,
J.G., Sippula, O., Zimmermann, R.°: Hyphenation of a EC / OC thermal-optical carbon analyzer to
photo-ionization time-of-flight mass spectrometry: An off-line aerosol mass spectrometric approach for
characterization of primary and secondary particulate matter. Atmos. Meas. Tech. 8, 3337-3353 (2015)
Diakopoulos, K.N., Lesina, M., Wörmann, S., Song, L., Aichler, M., Schild, L., Artati, A., Römisch-Margl,
W., Wartmann, T., Fischer, R., Kabiri, Y., Zischka, H., Halangk, W., Demir, I.E., Pilsak, C., Walch, A.K.,
Mantzoros, C.S., Steiner, J.M., Erkan, M., Schmid, R.M., Witt, H., Adamski, J., Algül, H.°: Impaired
autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.
Gastroenterology 148, 626-638 (2015)
Ding, L., Dean-Ben, X.L., Lutzweiler, C., Razansky, D., Ntziachristos, V.°: Efficient non-negative
constrained model-based inversion in optoacoustic tomography. Phys. Med. Biol. 60, 6733-6750 (2015)
Diot, G., Dima, A., Ntziachristos, V.°: Multispectral opto-acoustic tomography of exercised muscle
oxygenation. Opt. Lett. 40, 1496-1499 (2015)
Dondorp, W.°, de Wert, G., Bombard, Y., Bianchi, D.W., Bergmann, C., Borry, P., Chitty, L.S., Fellmann, F.,
Forzano, F., Hall, A., Henneman, L., Howard, H.C., Lucassen, A., Ormond, K., Peterlin, B., Radojkovic, D.,
Rogowski, W.H., Soller, M., Tibben, A., Tranebjærg, L., van El, C.G., Cornel, M.C.: Non-invasive prenatal
testing for aneuploidy and beyond: Challenges of responsible innovation in prenatal screening. Eur. J. Hum.
Genet. 23, 1438-1450 (2015)
page 158 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Dondorp, W.°, de Wert, G., Bombard, Y., Bianchi, D.W., Bergmann, C., Borry, P., Chitty, L.S., Fellmann, F.,
Forzano, F., Hall, A., Henneman, L., Howard, H.C., Lucassen, A., Ormond, K., Peterlin, B., Radojkovic, D.,
Rogowski, W.H., Soller, M., Tibben, A., Tranebjærg, L., van El, C.G., Cornel, M.C.: Non-invasive prenatal
testing for aneuploidy and beyond: Challenges of responsible innovation in prenatal screening. Summary
and recommendations. Eur. J. Hum. Genet., DOI: 10.1038/ejhg.2015.56 (2015)
Draisma, H.H.#°, Pool, R.#, Kobl, M., Jansen, R.C., Petersen, A.-K., Vaarhorst, A.A., Yet, I., Haller, T.,
Demirkan, A., Esko, T., Zhu, G., Böhringer, S., Beekman, M., van Klinken, J.B., Römisch-Margl, W., Prehn,
C., Adamski, J., de Craen, A.J., van Leeuwen, E.M., Amin, N., Dharuri, H., Westra, H.J., Franke, L., de
Geus, E.J., Hottenga, J.J., Willemsen, G., Henders, A.K., Montgomery, G.W., Nyholt, D.R., Whitfield, J.B.,
Penninx, B.W., Spector, T.D., Metspalu, A., Slagboom, P.E., van Dijk, K.W., 't Hoen, P.A., Strauch, K.,
Martin, N.G., van Ommen, G.J., Illig, T., Bell, J.T., Mangino, M., Suhre, K., McCarthy, M.I., Gieger, C.,
Isaacs, A., van Duijn, C.M., Boomsma, D.I.: Genome-wide association study identifies novel genetic variants
contributing to variation in blood metabolite levels. Nat. Commun. 6:7208 (2015)
#
#
Edelmann, F.T. , Niedner, A. , Niessing, D.°: ASH1 mRNP-core factors form stable complexes in absence
of cargo RNA at physiological conditions. RNA Biol. 12, 233-237 (2015)
Egusquiaguirre, S.P., Bézière, N., Pedraz, J.L., Hernández, R.M., Ntziachristos, V., Igartua, M.°:
Optoacoustic imaging enabled biodistribution study of cationic polymeric biodegradable nanoparticles.
Contrast Media Mol. Imaging 10, 421-427 (2015)
Emerenini, B.O.°, Hense, B.A., Kuttler, C., Eberl, H.J.: A mathematical model of quorum sensing induced
biofilm detachment. PLoS ONE 10:e0132385 (2015)
Emmanouilidis, L., Gopalswamy, M., Passon, D.M., Wilmanns, M., Sattler, M.: Structural biology of the
import pathways of peroxisomal matrix proteins. Biochim. Biophys. Acta-Mol. Cell Res. 1863, 804-813 (2016)
[published online 2015]
Erlmeier, F., Feuchtinger, A., Borgmann, D.M., Rudelius, M., Autenrieth, M., Walch, A.K., Weirich, G.°:
Supremacy of modern morphometry in typing renal oncocytoma and malignant look-alikes. Histochem. Cell
Biol. 144, 147-156 (2015)
Ermolayev, V.#, Dean-Ben, X.L.#, Mandal, S., Ntziachristos, V., Razansky, D.°: Simultaneous
visualization of tumor oxygenation, neovascularization and contrast agent perfusion by real-time
three-dimensional optoacoustic tomography. Eur. Radiol., DOI: 10.1007/s00330-015-3980-0 (2015)
Fehm, T., Dean-Ben, X.L., Razansky, D.°: Hybrid optoacoustic and ultrasound imaging in three dimensions
and real time by optical excitation of a passive element. Proc. SPIE 9323:93232X (2015)
Fehm, T., Dean-Ben, X.L., Schaur, P., Sroka, R., Razansky, D.°: Volumetric optoacoustic imaging feedback
during endovenous laser therapy - an ex vivo investigation. J. Biophotonics, DOI: 10.1002/jbio.201500210
(2015)
page 159 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Feng, L., Zhang, X., Wu, J.°, Efendiyev, M.A.: Necessary conditions for positivity-preserving property of
reaction-diffusion systems with delay. Electron. J. Qual. Theory Differ. Equations, accepted (2015)
Filipczyk, A.#, Marr, C.#, Hastreiter, S.#, Feigelman, J., Schwarzfischer, M., Hoppe, P.S., Loeffler, D.,
Kokkaliaris, K.D., Endele, M., Schauberger, B., Hilsenbeck, O., Skylaki, S., Hasenauer, J.,
Anastassiadis, K., Theis, F.J.°, Schroeder, T.°: Network plasticity of pluripotency transcription factors in
embryonic stem cells. Nat. Cell Biol. 17, 1235-1246 (2015)
Fischer, L., Arnold, M.°, Kirsch, F., Leidl, R.: Wirtschaftlichkeit des 21 Gene Tests in der Behandlung von
Patientinnen mit nodal-positivem Mammakarzinom. Gesundheitswesen, DOI: 10.1055/s-0035-1549989
(2015)
Fischer, M., Wohlfahrt, S., Varga, J., Matuschek, G., Saraji-Bozorgzad, M.R., Denner, T., Walte, A.,
Zimmermann, R.°: Optically heated ultra-fast-cycling gas chromatography module for rapid separation of
direct sampling and online monitoring applications. Anal. Chem. 87, 8634-8639 (2015)
Flynn, R.M.°, Mallén, G., Engel, M., Ahmed, A., Rossi, P.: Characterizing aquifer heterogeneity using
bacterial and bacteriophage tracers. J. Environ. Qual. 44, 1448-1458 (2015)
Ford, S.J., Dean-Ben, X.L., Razansky, D.°: Cardiac function and perfusion dynamics measured on a
beat-by-beat basis in the live mouse using ultra-fast 4D optoacoustic imaging. Proc. SPIE 9323:93231U
(2015)
#
#
Freiburger, L. , Sonntag, M. , Hennig, J., Li, J., Zou, P., Sattler, M.°: Efficient segmental isotope labeling
of multi-domain proteins using Sortase A. J. Biomol. NMR 63, 1-8 (2015)
Friberg, A.#, Thumann, S.#, Hennig, J., Zou, P., Nößner, E., Ling, P.D., Sattler, M.°, Kempkes, B.°: The
EBNA-2 N-terminal transactivation domain folds into a dimeric structure required for target gene activation.
PLoS Pathog. 11:e1004910 (2015)
Friedrich, N.°, Budde, K., Suhre, K., Völker, U., John, U., Felix, S.B., Kroemer, H.K., Grabe, H.J., Völzke, H.,
Nauck, M., Wallaschofski, H.: Sex differences in urine metabolites related with risk of diabetes using NMR
spectroscopy: Results of the study of health in pomerania. Metabolomics 11, 1405-1415 (2015)
Frikel, J., Quinto, E.T.: Artifacts in incomplete data tomography with applications to photoacoustic
tomography and sonar. SIAM J. Appl. Math. 75, 703-725 (2015)
Gabrys, H., Buettner, F., Schubert, K., Mescher, H., Debus, J., Sterzing, F., Bangert, M.: TH-AB-304-12:
Validation of a morphological xerostomia prediction model. Med. Phys. 42:3703 (2015)
Garcia-Allende, P., Koch, M., Glatz, J., Symvoulidis, P., Ntziachristos, V.°: Near-infrared fluorescence
molecular guidance in oncologic surgery and surveillance endoscopy. In: Proceedings (Optical Molecular
Probes, Imaging and Drug Delivery, OMP 2015). 2015
page 160 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Genitsch, V., Novotny, A., Seiler, C.A., Kröll, D., Walch, A.K., Langer, R.°: Epstein-Barr virus in
gastro-esophageal adenocarcinomas - single center experiences in the context of current literature. Front.
Oncol. 5:73 (2015)
Gersch, M., Famulla, K., Dahmen, M., Göbl, C., Malik, I., Richter, K., Korotkov, V.S., Sass, P.,
Rübsamen-Schaeff, H., Madl, T., Brötz-Oesterhelt, H.°, Sieber, S.A.°: AAA+ chaperones and
acyldepsipeptides activate the ClpP protease via conformational control. Nat. Commun. 6:6320 (2015)
Ghazaryan, A., Omar, M., Tserevelakis, G.J., Ntziachristos, V.°: Optoacoustic detection of tissue glycation.
Biomed. Opt. Express 6, 3149-3156 (2015)
Gilsbach, B.K., Messias, A.C., Ito, G., Sattler, M., Alessi, D.R., Wittinghofer, A., Kortholt, A.°: Structural
characterization of LRRK2 inhibitors. J. Med. Chem. 58, 3751-3756 (2015)
Goebl, S.°, He, X.°, Mai, S.T.°, Plant, C.°, Böhm, C.°: Finding the optimal subspace for clustering. In: Kumar,
R., Toivonen, H., Pei, J., Huang, J.Z., Wu, X. [Ed.]: (IEEE International Conference on Data Mining
(ICDM)). 2014, 130-139
Gomes de Matos, E.°, Kraus, L., Pabst, A., Piontek, D.: Does a change over all equal a change in all?
Testing for polarized alcohol use within and across socio-economic groups in Germany. Alcohol Alcohol. 50,
700-707 (2015)
Gottschalk, S., Fehm, T., Dean-Ben, X.L., Razansky, D.°: Noninvasive real-time visualization of multiple
cerebral hemodynamic parameters in whole mouse brains using five-dimensional optoacoustic tomography.
J. Cereb. Blood Flow Metab. 35, 531-535 (2015)
Gottschalk, S., Estrada, H., Degtyaruk, O., Rebling, J., Klymenko, O., Rosemann, M., Razansky, D.°:
Short and long-term phototoxicity in cells expressing genetic reporters under nanosecond laser exposure.
Biomaterials 69, 38-44 (2015)
Grabner, G.F., Eichmann, T.O., Wagner, B., Gao, Y., Farzi, A., Taschler, U., Radner, F.P., Schweiger, M.,
Lass, A., Holzer, P., Zinser, E., Tschöp, M.H., Yi, C.-X., Zimmermann, R.: Deletion of monoglyceride lpase
in astrocytes attenuates lipopolysaccharide-induced neuroinflammation. J. Biol. Chem. 291, 913-923 (2016)
[published online 2015]
Graessel, A., Hauck, S.M., von Toerne, C., Kloppmann, E., Goldberg, T., Koppensteiner, H., Schindler,
M., Knapp, B., Krause, L., Dietz, K., Schmidt-Weber, C.B., Suttner, K.°: A combined omics approach to
generate the surface atlas of human naive CD4+ T cells during early TCR activation. Mol. Cell. Proteomics
14, 2085-2102 (2015)
Grau, H., Berth, H., Lauterberg, J., Holle, R., Gräßel, E.: „Zuhause geht es nicht mehr“ – Gründe für den
Wechsel ins Pflegeheim bei Demenz. Gesundheitswesen, DOI: 10.1055/s-0035-1547301 (2015)
Grech, V.°, Scherb, H.: Hurricane Katrina: Influence on the male-to-female birth ratio. Med. Princ. Pract. 24,
477-485 (2015)
page 161 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
#
#
Griese, M. °, Kirmeier, H.G. , Liebisch, G., Rauch, D., Stückler, F., Schmitz, G., Zarbock, R.: Surfactant
lipidomics in healthy children and childhood interstitial lung disease. PLoS ONE 10:e0117985 (2015)
Grosche, A.°, Hauser, A., Lepper, M.F., Mayo, R., von Toerne, C., Merl-Pham, J., Hauck, S.M.°: The
proteome of native adult Muller glial cells from murine retina. Mol. Cell. Proteomics 15, 462-480 (2016)
[published online 2015]
#
#
#
Groß, C. , Steiger, K. , Sayyed, S. , Heid, I., Feuchtinger, A., Walch, A.K., Hess, J., Unger,
Zitzelsberger, H., Settles, M., Schlitter, A.M., Dworniczak, J., Altomonte, J., Ebert, O., Schwaiger,
Rummeny, E.J., Steingötter, A., Esposito, I., Braren, R.°: Model matters: Differences in orthotopic
hepatocellular carcinoma physiology determine therapy response to sorafenib. Clin. Cancer Res.
4440-4450 (2015)
K.,
M.,
rat
21,
Gutierrez, B., Mateus, D., Shiban, E., Meyer, B.U., Lehmberg, J., Navab, N.A.: A sparse approach to build
shape models with routine clinical data. In: (IEEE International Symposium on Biomedical Imaging, ISBI).
Piscataway, NJ: IEEE, 2014, 258-261
Haase, K., Mösch, A., Frishman, D.: Differential expression analysis of human endogenous retroviruses
based on ENCODE RNA-seq data. BMC Med. Genomics 8:71 (2015)
Haase, K., Raffegerst, S.H., Schendel, D.J., Frishman, D.°: Expitope: A web server for epitope expression.
Bioinformatics 31, 1854-1856 (2015)
Hacker, C., Christ, N.A., Duchardt-Ferner, E., Korn, S., Göbl, C., Berninger, L., Düsterhus, S., Hellmich,
U.A., Madl, T., Kötter, P., Entian, K.D., Wöhnert, J.°: The solution structure of the lantibiotic immunity protein
NisI and its interactions with Nisin. J. Biol. Chem. 290, 28869-28886 (2015)
Haghverdi, L., Buettner, F., Theis, F.J.°: Diffusion maps for high-dimensional single-cell analysis of
differentiation data. Bioinformatics 31, 2989-2998 (2015)
Halama, A., Guerrouahen, B.S., Pasquier, J., Diboun, I., Karoly, E.D., Suhre, K., Rafii, A.°: Metabolic
signatures differentiate ovarian from colon cancer cell lines. J. Transl. Med. 13:223 (2015)
Halama, A., Horsch, M., Kastenmüller, G., Möller, G., Kumar, P., Prehn, C., Laumen, H., Hauner, H.,
Hrabě de Angelis, M., Beckers, J., Suhre, K., Adamski, J.°: Metabolic switch during adipogenesis: From
branched chain amino acid catabolism to lipid synthesis. Arch. Biochem. Biophys. 589, 93-107 (2015)
Han, Y.°, Ntziachristos, V., Rosenthal, A.: A system analysis and image reconstruction tool for
optoacoustic imaging with finite-aperture detectors. Proc. SPIE 9539:953915 (2015)
Han, Y., Tzoumas, S., Nunes, A., Ntziachristos, V., Rosenthal, A.°: Sparsity-based acoustic inversion in
cross-sectional multiscale optoacoustic imaging. Med. Phys. 42, 5444-5452 (2015)
Haslbeck, V., Drazic, A., Eckl, J.M., Alte, F., Helmuth, M., Popowicz, G.M., Rattei, T., Braun, F., Weiwad,
M., Fischer, G., Gemmecker, G., Sattler, M., Striggow, F., Groll, M., Richter, K.°: Selective activators of
protein phosphatase 5 target the auto-inhibitory mechanism. Biosci. Rep. 35:e00210 (2015)
page 162 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Haslbeck, V., Eckl, J.M., Drazic, A., Rutz, D.A., Lorenz, O.R., Zimmermann, K., Kriehuber, T., Lindemann,
C., Madl, T., Richter, K.: The activity of protein phosphatase 5 towards native clients is modulated by the
middle- and C-terminal domains of Hsp90. Sci. Rep. 5:17058 (2015)
He, H., Mandal, S., Bühler, A., Dean-Ben, X.L., Razansky, D., Ntziachristos, V.°: Improving optoacoustic
image quality via geometric pixel super-resolution approach. IEEE Trans. Med. Imaging 35, 812-818 (2016)
[published online 2015]
He, H., Bühler, A.°, Ntziachristos, V.°: Optoacoustic endoscopy with curved scanning. Opt. Lett. 40,
4667-4670 (2015)
He, X., Hartlieb, E., Rothmund, L., Waschke, J., Wu, X., van Landuyt, K.L., Milz, S., Michalke, B., Hickel, R.,
Reichl, F.X., Högg, C.H.°: Intracellular uptake and toxicity of three different Titanium particles. Dent. Mater.
31, 734-744 (2015)
#
#
Helmbrecht, M.S. , Soellner, H. , Castiblanco-Urbina, M.A., Winzeck, S., Sundermeier, J., Theis, F.J.,
Fouad, K., Huber, A.B.°: A critical period for postnatal adaptive plasticity in a model of motor axon miswiring.
PLoS ONE 10:e0123643 (2015)
Helmbrecht, M.S.°, Soellner, H., Truckenbrodt, A.M., Sundermeier, J., Cohrs, C., Hans, W., Hrabě de
Angelis, M., Feuchtinger, A., Aichler, M., Fouad, K., Huber, A.B.°: Loss of Npn1 from motor neurons
causes postnatal deficits independent from Sema3A signaling. Dev. Biol. 399, 2-14 (2015)
Hennig, J., Sattler, M.°: Deciphering the protein-RNA recognition code: Combining large-scale quantitative
methods with structural biology. Bioessays 37, 899-908 (2015)
Hennig, J., Andrésen, C., Museth, A.K., Lundström, P., Tibell, L.A.E., Jönsson, B.H.°: Local destabilization
of the metal-binding region in human copper-zinc superoxide dismutase by remote mutations is a possible
determinant for progression of ALS. Biochemistry 54, 323-333 (2015)
Hennig, J., Warner, L., Simon, B.H., Geerlof, A., Mackereth, C.D., Sattler, M.°: Structural analysis of
protein-RNA complexes in solution using NMR paramagnetic relaxation enhancements. Methods Enzymol.
558, 333-362 (2015)
Hense, B.A.°, Schuster, M.°: Core principles of bacterial autoinducer systems. Microbiol. Mol. Biol. Rev. 79,
153-169 (2015)
Herder, C.°, Bongaerts, B.W., Ouwens, D.M., Rathmann, W., Heier, M., Carstensen-Kirberg, M., Koenig, W.,
Thorand, B., Roden, M., Meisinger, C., Ziegler, D., KORA Study Group (Gieger, C., Grallert, H., Heinrich,
J., Holle, R., Leidl, R., Peters, A., Strauch, K.): Low serum omentin levels in the elderly population with
type 2 diabetes and polyneuropathy. Diabet. Med. 32, 1479-1483 (2015)
Hertz-Schünemann, R., Ehlert, S., Streibel, T., Liu, C., McAdam, K., Baker, R.R., Zimmermann, R.°:
High-resolution time and spatial imaging of tobacco and its pyrolysis products during a cigarette puff by
microprobe sampling photoionisation mass spectrometry. Anal. Bioanal. Chem. 407, 2293-2299 (2015)
page 163 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Hocking, H.G., Häse, F., Madl, T., Zacharias, M., Rief, M., Žoldák, G.°: A compact native 24-residue
supersecondary structure derived from the villin headpiece subdomain. Biophys. J. 108, 678-686 (2015)
Hoffmann, F.S., Kühn, P., Laurent, S.A., Hauck, S.M., Berer, K., Wendlinger, S.A., Krumbholz, M., Khademi,
M., Olsson, T., Dreyling, M., Pfister, H., Alexander, T., Hiepe, F., Kümpfel, T., Crawford, H.C., Wekerle, H.,
Hohlfeld, R., Lichtenthaler, S.F., Meinl, E.°: The immunoregulator soluble TACI is released by ADAM10 and
reflects B cell activation in autoimmunity. J. Immunol. 194, 542-552 (2015)
Hofmeister, C., Maier, W., Mielck, A., Stahl, L., Breckenkamp, J.°, Razum, O.: Regionale Deprivation in
Deutschland: Bundesweite Analyse des Zusammenhangs mit Mortalität unter Verwendung des ‚German
Index of Multiple Deprivation (GIMD)‘. Gesundheitswesen 78, 42-48 (2015)
Hohm, K., Storath, M.°, Weinmann, A.: An algorithmic framework for Mumford-Shah regularization of
inverse problems in imaging. Inverse Probl. 31:115011 (2015)
Horn, A.P., Hennig, J., Ahmed, Y.L., Stier, G., Wild, K., Sattler, M., Sinning, I.: Structural basis for cpSRP43
chromodomain selectivity and dynamics in Alb3 insertase interaction. Nat. Commun. 6:8875 (2015)
Huber, M.B.°, Wacker, M., Vogelmeier, C.F., Leidl, R.: Excess costs of comorbidities in chronic obstructive
pulmonary disease: A systematic review. PLoS ONE 10:e0123292 (2015)
Hug, S.°, Schwarzfischer, M., Hasenauer, J., Marr, C., Theis, F.J.°: An adaptive scheduling scheme for
calculating Bayes factors with thermodynamic integration using Simpson’s rule. Stat. Comp., DOI:
10.1007/s11222-015-9550-0 (2015)
Idler, N., Teuner, C.M., Hunger, M., Holle, R.°, Ortlieb, S., Schulz, H., Bauer, C.P., Hoffmann, U.,
Koletzko, S., Lehmann, I., von Berg, A., Berdel, D., Hoffmann, B., Schaaf, B., Heinrich, J., Wolfenstetter,
S.B.: The association between physical activity and healthcare costs in children - results from the GINIplus
and LISAplus cohort studies. BMC Public Health 15:437 (2015)
Illner, K., Miettinen, J., Fuchs, C., Taskinen, S., Nordhausen, K., Oja, H., Theis, F.J.°: Model selection
using limiting distributions of second-order blind source separation algorithms. Signal Process. 113, 95-103
(2015)
Ilmonen, P.°, Nordhausen, K., Oja, H., Theis, F.J.: An affine equivariant robust second-order BSS method.
Lecture Notes Comp. Sci. 9237, 328-335 (2015)
Ingold, I., Aichler, M., Yefremova, E., Roveri, A., Buday, K., Doll, S., Tasdemir, A., Hoffard, N., Wurst,
W., Walch, A.K., Ursini, F., Friedmann Angeli, J.P., Conrad, M.°: Expression of a catalytically inactive
mutant form of Glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility. J. Biol.
Chem. 290, 14668-14678 (2015)
Iske, A.°, Demaret, L.°: Optimally sparse image approximation by adaptive linear splines over anisotropic
triangulations. In: (International Conference on Sampling Theory and Applications, SampTA 2015). 2015,
463-467
page 164 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
#
#
Istvanffy, R. , Vilne, B. , Schreck, C., Ruf, F., Pagel, C., Grziwok, S., Henkel, L., Prazeres da Costa, O.,
Berndt, J., Stuempflen, V., Götze, K.S., Schiemann, M., Peschel, C., Mewes, H.-W., Oostendorp, R.A.°:
Stroma-derived connective tissue growth factor maintains cell cycle progression and repopulation activity of
hematopoietic stem cells in vitro. Stem Cell Rep. 5, 702-715 (2015)
Italia, S.°, Brüske, I., Heinrich, J., Berdel, D., von Berg, A., Lehmann, I., Standl, M., Wolfenstetter, S.B.: A
longitudinal comparison of drug use among 10-year-old children and 15-year-old adolescents from the
German GINIplus and LISAplus birth cohorts. Eur. J. Clin. Pharmacol. 72, 301-310 (2016) [published online
2015]
Italia, S.°, Brand, H., Heinrich, J., Berdel, D., von Berg, A., Wolfenstetter, S.B.: Utilization of
Complementary and Alternative Medicine (CAM) among children from a German birth cohort (GINIplus):
Patterns, costs, and trends of use. BMC Complement. Altern. Med. 15:569 (2015)
Italia, S.°, Brand, H., Heinrich, J., Berdel, D., von Berg, A., Wolfenstetter, S.B.: Utilization of
self-medication and prescription drugs among 15-year-old children from the German GINIplus birth cohort.
Pharmacoepidemiol. Drug Saf. 24, 1133–1143 (2015)
Jiang, Y.°, Sigmund, F., Reber, J., Dean-Ben, X.L., Glasl, S., Kneipp, M., Estrada, H., Razansky, D.,
Ntziachristos, V., Westmeyer, G.G.: Violacein as a genetically-controlled, enzymatically amplified and
photobleaching-resistant chromophore for optoacoustic bacterial imaging. Sci. Rep. 5:11048 (2015)
Kanashova, T.#, Popp, O.#, Orasche, J., Karg, E.W., Harndorf, H., Stengel, B., Sklorz, M., Streibel, T.,
Zimmermann, R., Dittmar, G.A.G.°: Differential proteomic analysis of mouse macrophages exposed to
adsorbate-loaded heavy fuel oil derived combustion particles using an automated sample-preparation
workflow. Anal. Bioanal. Chem. 407, 5965-5976 (2015)
Kandemir, M., Feuchtinger, A., Walch, A.K., Hamprecht, F.A.: Digital pathology: Multiple instance learning
can detect Barrett's cancer. In: (IEEE International Symposium on Biomedical Imaging, ISBI). Piscataway,
NJ: IEEE, 2014, 1348-1351
Karabulut, N.P., Frishman, D.°: Tissue-specific sequence and structural environments of lysine acetylation
sites. J. Struct. Biol. 191, 39-48 (2015)
Karg, E.W.°, Dragan, G.-C., Ferron, G.A., Nordsieck, H., Blaskowitz, M., Friedrich, C., Kohlmeier, V.,
Moehlmann, C., Schnelle-Kreis, J., Stanglmaier, S., Zimmermann, R., Breuer, D.: Dynamisches Verhalten
von Aerosolen aus semivolatilen Komponenten. Gefahrstoffe Reinhalt. Luft 75, 265-274 (2015)
Kastenmüller, G., Raffler, J., Gieger, C., Suhre, K.°: Genetics of human metabolism: An update. Hum.
Mol. Genet. 24, R93-R101 (2015)
Kaufmann, S., Fuchs, C., Gonik, M., Khrameeva, E.E., Mironov, A.A., Frishman, D.°: Inter-chromosomal
contact networks provide insights into mammalian chromatin organization. PLoS ONE 10:e0126125 (2015)
page 165 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Kavšček, M., Bhutada, G., Madl, T., Natter, K.: Optimization of lipid production with a genome-scale model of
Yarrowia lipolytica. BMC Syst. Biol. 9:72 (2015)
Kazeroonian, A.°, Theis, F.J.°, Hasenauer, J.°: Modeling of stochastic biological processes with
non-polynomial propensities using non-central conditional moment equation. IFAC Proc. 19, 1729-1735
(2014)
Keller, I.E., Vosyka, O., Takenaka, S., Kloß, A., Dahlmann, B., Willems, L.I., Verdoes, M., Overkleeft, H.S.,
Marcos, E., Adnot, S., Hauck, S.M., Ruppert, C., Günther, A., Herold, S., Ohno, S., Adler, H., Eickelberg,
O., Meiners, S.°: Regulation of immunoproteasome function in the lung. Sci. Rep. 5:10230 (2015)
Kempf, S.J., von Toerne, C., Hauck, S.M., Atkinson, M.J., Benotmane, M.A., Tapio, S.°: Long-term
consequences of in utero irradiated mice indicate proteomic changes in synaptic plasticity related signalling.
Proteome Sci. 13:26 (2016) [published online 2015]
Kempf, S.J., Mörtl, S., Sepe, S., von Toerne, C., Hauck, S.M., Atkinson, M.J., Mastroberardino, P.G.,
Tapio, S.°: Low-dose ionizing radiation rapidly affects mitochondrial and synaptic signaling pathways in
murine hippocampus and cortex. J. Proteome Res. 14, 2055-2064 (2015)
Kempf, S.J., Sepe, S., von Toerne, C., Janik, D., Neff, F., Hauck, S.M., Atkinson, M.J., Mastroberardino,
P.G., Tapio, S.°: Neonatal irradiation leads to persistent proteome alterations involved in synaptic plasticity
in the mouse hippocampus and cortex. J. Proteome Res. 14, 4674-4686 (2015)
Kiermayer, C.°, Northrup, E., Schrewe, A., Walch, A.K., Hrabě de Angelis, M., Schoensiegel, F.,
Zischka, H., Prehn, C., Adamski, J., Bekeredjian, R., Ivandic, B., Kupatt, C., Brielmeier, M.: Heart-specific
knockout of the mitochondrial Thioredoxin reductase (Txnrd2) induces metabolic and contractile dysfunction
in the aging myocardium. J. Am. Heart Assoc. 4:e002153 (2015)
Kirchberger, I.°, Hunger, M., Stollenwerk, B., Seidl, H., Burkhardt, K., Kuch, B., Meisinger, C., Holle, R.:
Effects of a 3-year nurse-based case management in aged patients with acute myocardial infarction on
rehospitalisation, mortality, risk factors, physical functioning and mental health. A secondary analysis of the
randomized controlled KORINNA study. PLoS ONE 10:e0116693 (2015)
Kirsch, F.°: A systematic review of quality and cost-effectiveness derived from Markov models evaluating
smoking cessation interventions in patients with chronic obstructive pulmonary disease. Expert Rev.
Pharmacoecon. Outcomes Res. 15, 301-316 (2015)
Kirscher, L., Dean-Ben, X.L., Scadeng, M., Zaremba, A., Zhang, Q., Kober, C., Fehm, T.F., Razansky, D.,
Ntziachristos, V., Stritzker, J., Szalay, A.A.°: Doxycycline inducible melanogenic vaccinia virus as
theranostic anti-cancer agent. Theranostics 5, 1045-1057 (2015)
#
#
Kirschner, M. °, Bauch, A. , Agusti, A., Hilke, S., Merk, S., Pison, C., Roldan, J., Seidenath, B., Wilken, M.,
Wouters, E.F., Mewes, H.-W., Heumann, K., Maier, D.: Implementing systems medicine within healthcare.
Genome Med. 7:102 (2015)
page 166 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Kleeblatt, J., Schubert, J.K., Zimmermann, R.°: Detection of gaseous compounds by needle trap sampling
and direct thermal-desorption photoionization mass spectrometry: Concept and demonstrative application to
breath gas analysis. Anal. Chem. 87, 1773–1781 (2015)
Kleeblatt, J., Stengel, B., Radischat, C., Passig, J., Streibel, T., Sippula, O., Rabe, R., Harndorf, H.,
Zimmermann, R.°: Needle trap sampling thermal-desorption resonance enhanced multiphoton ionization
time-of-flight mass spectrometry for analysis of marine diesel engine exhaust. Anal. Methods 7, 3608-3617
(2015)
Kneipp, M., Turner, J.E., Estrada, H., Rebling, J., Shoham, S., Razansky, D.°: Effects of the murine skull
in optoacoustic brain microscopy. J. Biophotonics 9, 117-123 (2016) [published online 2015]
Kneipp, M., Estrada, H., Lauri, A., Turner, J.E., Ntziachristos, V., Westmeyer, G.G., Razansky, D.°:
Volumetric tracking of migratory melanophores during zebrafish development by optoacoustic microscopy.
Mech. Dev. 138, 300-304 (2015)
Knowlton, S.M., Sadasivam, M., Tasoglu, S.°: Microfluidics for sperm research. Trends Biotechnol. 33,
221-229 (2015)
Kohler, D.°, Marzouk, Y.M., Müller, J., Wever, U.: A new network approach to Bayesian inference in partial
differential equations. Int. J. Numer. Methods Eng. 104, 313-329 (2015)
Kohler, D.°, Müller, J.°, Wever, U.°: Cellular non-deterministic automata and partial differential equations.
Physica D 311-312, 1-16 (2015)
Kohlmeier, V., Dragan, G.-C., Karg, E.W., Schnelle-Kreis, J., Breuer, D., Forbes, P.B.C., Rohwer, E.R.,
Zimmermann, R.: The suitability of Multichannel-PDMS-Denuders for the gas-particle-partitioning of SVOCs.
Gefahrstoffe Reinhalt. Luft 75, 383-389 (2015)
Kolder, I.C., Tanck, M.W., Postema, P.G., Barc, J., Sinner, M.F., Zumhagen, S., Husemann, A., Stallmeyer,
B., Koopmann, T.T., Hofman, N., Pfeufer, A., Lichtner, P., Meitinger, T., Beckmann, B.M., Myerburg, R.J.,
Bishopric, N.H., Roden, D.M., Kääb, S., Wilde, A.A., Schott, J.J., Schulze-Bahr, E., Bezzina, C.R.°: Analysis
for genetic modifiers of disease severity in patients with long QT syndrome type 2. Circ. Cardiovasc. Genet.
8, 447-456 (2015)
Kondofersky, I., Fuchs, C., Theis, F.J.°: Identifying latent dynamic components in biological systems. IET
Syst. Biol. 9, 193-203 (2015)
Kong, B., Wu, W., Cheng, T., Schlitter, A.M., Qian, C., Bruns, P., Jian, Z., Jager, C., Regel, I., Raulefs, S.,
Behler, N., Irmler, M., Beckers, J., Friess, H., Erkan, M., Siveke, J.T., Tannapfel, A., Hahn, S.A., Theis,
F.J., Esposito, I., Kleeff, J., Michalski, C.W.°: A subset of metastatic pancreatic ductal adenocarcinomas
depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling. Gut 65, 647-657
(2016) [published online 2015]
page 167 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Kong, B., Bruns, P., Raulefs, S., Rieder, S., Paul, L., da Costa, O.P., Buch, T., Theis, F.J., Michalski, C.W.,
Kleeff, J.: Metabolism gene signatures and surgical site infections in abdominal surgery. Int. J. Surg. 14,
67-74 (2015)
Kopanitsa, G.°, Veseli, H., Yampolsky, V.: Development, implementation and evaluation of an information
model for archetype based user responsive medical data visualization. J. Biomed. Inform. 55, 196-205
(2015)
Kovac, M., Blattmann, C., Ribi, S., Smida, J., Müller, N.S., Engert, F., Castro-Giner, F., Weischenfeldt, J.,
Kovacova, M., Krieg, A., Andreou, D., Tunn, P.U., Dürr, H.R., Rechl, H.P., Schaser, K.D., Melcher, I.,
Burdach, S., Kulozik, A., Specht, K., Heinimann, K., Fulda, S., Bielack, S., Jundt, G., Tomlinson, I., Korbel,
J.O., Nathrath, M., Baumhoer, D.: Exome sequencing of osteosarcoma reveals mutation signatures
reminiscent of BRCA deficiency. Nat. Commun. 6:8940 (2015)
Kraus, L.°, Tryggvesson, K., Pabst, A., Room, R.: Involvement in alcohol-related verbal or physical
aggression. Does social status matter? Nord. Stud. Alcohol Drugs 32, 449-463 (2015)
Kraus, L.°, Pabst, A., Piontek, D., Gmel, G., Shield, K.D., Frick, H., Rehm, J.: Temporal changes in
alcohol-related morbidity and mortality in Germany. Eur. Addict. Res. 21, 262-272 (2015)
Krause, L., Haubold, B., Börsch-Haubold, A.G.°: Social exclusion changes histone modifications H3K4me3
and H3K27ac in liver tissue of wild house mice. PLoS ONE 10:e0133988 (2015)
Kreuter, M.°, Herth, F., Wacker, M., Leidl, R., Hellmann, A., Pfeifer, M., Behr, J., Witt, S., Kauschka, D.,
Mall, M., Günther, A., Markart, P.: Exploring clinical and epidemiological characteristics of interstitial lung
diseases: Rationale, aims, and design of a nationwide prospective registry - the EXCITING-ILD registry.
Biomed Res. Int. 2015:123876 (2015)
Kristensen, D.M., Saeed, U., Frishman, D., Koonin, E.V.: A census of α-helical membrane proteins in
double-stranded DNA viruses infecting bacteria and archaea. BMC Bioinformatics 16:380 (2015)
#
#
Krumsiek, J. , Mittelstraß, K. , Do, K.T., Stückler, F., Ried, J.S., Adamski, J., Peters, A., Illig, T.,
Kronenberg, F., Friedrich, N., Nauck, M., Pietzner, M., Mook-Kanamori, D.O., Suhre, K., Gieger, C.,
Grallert, H., Theis, F.J.°, Kastenmüller, G.°: Gender-specific pathway differences in the human serum
metabolome. Metabolomics 11, 1815-1833 (2015)
Kumar, P., Halama, A., Hayat, S., Billing, A.M., Gupta, M., Yousri, N.A., Smith, G.M., Suhre, K.°:
MetaRNA-Seq: An interactive tool to browse and annotate metadata from RNA-Seq studies. Biomed Res.
Int. 2015:318064 (2015)
Kunis, S.°, Peter, T.°, Römer, T.°, von der Ohe, U.°: A multivariate generalization of Prony's method. Linear
Algebra Appl. 490, 31-47 (2016) [published online 2015]
page 168 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Lahiri, S., Sun, N., Solis-Mezarino, V., Fedisch, A., Ninkovic, J., Feuchtinger, A., Götz, M., Walch, A.K.,
Imhof, A.°: In situ detection of histone variants and modifications in mouse brain using imaging mass
spectrometry. Proteomics 16, 437-447 (2016) [published online 2015]
Lan, D., Popowicz, G.M., Pavlidis, I.V., Zhou, P., Bornscheuer, U.T., Wang, Y.°: Conversion of a mono- and
diacylglycerol lipase into a triacylglycerol lipase by protein engineering. ChemBioChem 16, 1431-1434
(2015)
Lan, D., Wang, Q., Popowicz, G.M., Yang, B., Tang, Q., Wang, Y.°: The role of residues 103,104 and 278
on the activity of SMG1 lipase from Malassezia globosa: A site-directed mutagenesis studies. J. Microbiol.
Biotechnol. 25, 1827-1834 (2015)
Lau, K., Junk, R., Klingbeil, S., Schümann, U., Streibel, T.°: Analysis of internal common rail injector
deposits via thermodesorption photon ionization time of flight mass spectrometry. Energy Fuels 29,
5625-5632 (2015)
Laurent, S.A., Hoffmann, F.S., Kuhn, P.H., Cheng, Q., Chu, Y., Schmidt-Supprian, M., Hauck, S.M., Schuh,
E., Krumbholz, M., Rübsamen, H., Wanngren, J., Khademi, M., Olsson, T., Alexander, T., Hiepe, F., Pfister,
H.W., Weber, F., Jenne, D., Wekerle, H., Hohlfeld, R., Lichtenthaler, S.F., Meinl, E.°: γ-secretase directly
sheds the survival receptor BCMA from plasma cells. Nat. Commun. 6:7333 (2015)
Laxy, M.°, Hunger, M., Stark, R.G., Meisinger, C., Kirchberger, I., Heier, M., von Scheidt, W., Holle, R.:
The burden of diabetes mellitus in patients with coronary heart disease: A methodological approach to
assess quality-adjusted life-years based on individual-level longitudinal survey data. Value Health 18,
969-976 (2015)
Laxy, M.°, Stark, R.G., Meisinger, C., Kirchberger, I., Heier, M., von Scheidt, W., Holle, R.: The
effectiveness of German Disease Management Programs (DMPs) in patients with type 2 diabetes mellitus
and coronary heart disease: Results from an observational longitudinal study. Diabetol. Metab. Syndr. 7:77
(2015)
Leuchner, M.°, Gubo, S., Schunk, C., Wastl, C., Kirchner, M., Menzel, A., Plaß-Dülmer, C.: Can positive
matrix factorization help to understand patterns of organic trace gases at the continental Global Atmosphere
Watch site Hohenpeissenberg? Atmos. Chem. Phys. 15, 1221-1236 (2015)
Lin, H.-C., Chekkoury, A., Omar, M., Schmitt-Manderbach, T., Koberstein-Schwarz, B., Mappes, T.,
López-Schier, H., Razansky, D., Ntziachristos, V.°: Selective plane illumination optical and optoacoustic
microscopy for postembryonic imaging. Laser Photon. Rev. 9, L29-L34 (2015)
Linnemann, J., Miura, H., Meixner, L.K., Irmler, M., Kloos, U., Hirschi, B., Bartsch, H.S., Sass, S.,
Beckers, J., Theis, F.J., Gabka, C., Sotlar, K., Scheel, C.°: Quantification of regenerative potential in
primary human mammary epithelial cells. Development 142, 3239-3251 (2015)
page 169 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Livshits, G., Macgregor, A.J., Gieger, C., Malkin, I., Moayyeri, A., Grallert, H., Emeny, R.T., Spector, T.,
Kastenmüller, G., Williams, F.M.: An omics investigation into chronic widespread musculoskeletal pain
reveals epiandrosterone sulfate as a potential biomarker. Pain 156, 1845-1851 (2015)
Loedige, I.°, Jakob, L., Treiber, T., Ray, D.W., Stotz, M., Treiber, N., Hennig, J., Cook, K.B., Morris, Q.,
Hughes, T.R., Engelmann, J.C., Krahn, M.P., Meister, G.°: The crystal structure of the NHL domain in
complex with RNA reveals the molecular basis of Drosophila brain-tumor-mediated gene regulation. Cell
Rep. 13, 1206-1220 (2015)
Loos, C., Marr, C., Theis, F.J., Hasenauer, J.°: Approximate bayesian computation for stochastic
single-cell time-lapse data using multivariate test statistics. Lecture Notes Comp. Sci. 9308, 52-63 (2015)
Lorber, B.#°, Chew, D.J.#, Hauck, S.M.#, Chong, R.S., Fawcett, J.W., Martin, K.R.°: Retinal glia promote
dorsal root ganglion axon regeneration. PLoS ONE 10:e0115996 (2015)
Lotty, E.Y., Hämmerling, C., Mielck, A.°: Gesundheitszustand von Menschen ohne Krankenversicherung
und von Menschen ohne legalen Aufenthaltsstatus: Analyse von Daten der Malteser Migranten Medizin
(MMM) in München. Gesundheitswesen 77, e143-e152 (2015)
Lutzweiler, C., Tzoumas, S., Rosenthal, A., Ntziachristos, V., Razansky, D.°: High-throughput
sparsity-based inversion scheme for optoacoustic tomography. IEEE Trans. Med. Imaging 35, 674-684
(2016) [published online 2015]
Mai, H.J., Lindermayr, C., von Toerne, C., Fink-Straube, C., Durner, J., Bauer, P.°: Iron and FER-LIKE
IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (FIT)-dependent regulation of proteins and
genes in Arabidopsis thaliana roots. Proteomics 15, 3030-3047 (2015)
Mai, S.T.°, He, X., Feng, J., Plant, C., Böhm, C.: Anytime density-based clustering of complex data. Knowl.
Inf. Syst. 45, 319-355 (2015)
Mainz, A., Peschek, J., Stavropoulou, M., Back, K.C., Bardiaux, B., Asami, S., Prade, E., Peters, C.,
Weinkauf, S., Buchner, J., Reif, B.°: The chaperone αB-crystallin uses different interfaces to capture an
amorphous and an amyloid client Nat. Struct. Mol. Biol. 22, 898-905 (2015)
Mandal, S., Dean-Ben, X.L., Burton, N.C., Razansky, D.°: Extending biological imaging to the fifth
dimension: Evolution of volumetric small animal multispectral optoacoustic tomography. IEEE Pulse 6, 47-53
(2015)
Mandal, S., Nasonova, E., Dean-Ben, X.L., Razansky, D.°: Fast calibration of speed-of-sound using
temperature prior in whole-body small animal optoacoustic imaging. Proc. SPIE 9323:93232Q (2015)
Masserdotti, G.#, Gillotin, S.#, Sutor, B., Drechsel, D., Irmler, M., Jørgensen, H.F., Sass, S., Theis, F.J.,
Beckers, J., Berninger, B., Guillemot, F.°, Götz, M.°: Transcriptional mechanisms of proneural factors and
REST in regulating neuronal reprogramming of astrocytes. Cell Stem Cell 17, 74-88 (2015)
Massopust, P.°: On local fractal functions in Banach spaces. AIP Conf. Proc. 1648:640002 (2015)
page 170 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
#
#
Mathew, L.S. , Seidel, M. , George, B., Mathew, S., Spannagl, M., Haberer, G., Torres, M.F., Al-Dous, E.K.,
Al-Azwani, E.K., Diboun, I., Krueger, R.R., Mayer, K.F.X., Mohamoud, Y.A., Suhre, K., Malek, J.A.°: A
genome-wide survey of date palm cultivars supports two major subpopulations in Phoenix dactylifera. Genes
Genomes Genetics G3 5, 1429-1438 (2015)
Matos, M.R.#, Knapp, B.#°, Kaderali, L.: lpNet: A linear programming approach to reconstruct signal
transduction networks. Bioinformatics 31, 3231-3233 (2015)
Maurus, S., Plant, C.: Ternary matrix factorization. In: (IEEE International Conference on Data Mining
(ICDM)). Piscataway, NJ: IEEE, 2014, 400-409
Menni, C.#, Graham, D.#, Kastenmüller, G., Alharbi, N.H., Alsanos, S.M., McBride, M., Mangino, M.,
Titcombe, P., Shin, S.Y., Psatha, M., Geisendorfer, T., Huber, A., Peters, A., Wang-Sattler, R., Xu, T.,
Brosnan, M.J., Trimmer, J., Reichel, C., Mohney, R.P., Soranzo, N., Edwards, M.H., Cooper, C., Church,
A.C., Suhre, K., Gieger, C., Dominiczak, A.F., Spector, T.D., Padmanabhan, S.°, Valdes, A.M.: Metabolomic
identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension 66,
422-429 (2015)
Mercep, E., Jeng, G., Morscher, S., Li, P.C., Razansky, D.°: Hybrid optoacoustic tomography and
pulse-echo ultrasonography using concave arrays. IEEE Trans. Ultrason. Ferroelectr. Freq. Control. 62,
1651-1661 (2015)
Mercep, E.°, Burton, N.C., Claussen, J., Razansky, D.: Whole-body live mouse imaging by hybrid
reflection-mode ultrasound and optoacoustic tomography. Opt. Lett. 40, 4643-4646 (2015)
Merl-Pham, J.°, Gruhn, F.°, Hauck, S.M.°: Proteomic profiling of cigarette smoke induced changes in retinal
pigment epithelium cells. Adv. Exp. Med. Biol. 854, 785-791 (2016)
Meyer, N.H., Mayerhofer, H., Tripsianes, K., Blindow, S., Barths, D., Mewes, A., Weimar, T., Köhli, T.,
Bade, S., Madl, T., Frey, A., Haas, H., Müller-Dieckmann, J., Sattler, M., Schramm, G.°: A crystallin fold in
the interleukin-4-inducing principle of Schistosoma mansoni eggs (IPSE/alpha-1) mediates IgE binding for
antigen-independent basophil activation. J. Biol. Chem. 290, 22111-22126 (2015)
Meyer, S.U.°, Sass, S., Müller, N.S., Krebs, S., Bauersachs, S., Kaiser, S., Blum, H., Thirion, C., Krause, S.,
Theis, F.J., Pfaffl, M.W.: Integrative analysis of MicroRNA and mRNA data reveals an orchestrated function
of MicroRNAs in skeletal myocyte differentiation in response to TNF-α or IGF1. PLoS ONE 10:e0135284
(2015)
Midha, N., Mandal, S.: Making health care universally accessible : The emergence of telemedicine as a core
necessity. IEEE Pulse 5, 4-7 (2014)
Miettinen, J.°, Illner, K., Nordhausen, K., Oja, H., Taskinen, S., Theis, F.J.: Separation of uncorrelated
stationary time series using autocovariance matrices. J. Time Ser. Anal. 37, 337-354 (2016) [published
online 2015]
page 171 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Mohajerani, P.°, Ntziachristos, V.°: An inversion scheme for hybrid fluorescence molecular tomography
using a fuzzy inference system. IEEE Trans. Med. Imaging 35, 381-390 (2016) [published online 2015]
Mohajerani, P., Tzoumas, S., Rosenthal, A., Ntziachristos, V.°: Optical and optoacoustic based
tomography : Theory and current challenges for deep tissue imaging of optical contrast. IEEE Signal
Process. Lett. 32, 88-100 (2015)
Moignard, V., Woodhouse, S., Haghverdi, L., Lilly, A.J., Tanaka, Y., Wilkinson, A.C., Buettner, F.,
Macaulay, I.C., Jawaid, W., Diamanti, E., Nishikawa, S.I., Piterman, N., Kouskoff, V., Theis, F.J., Fisher, J.°,
Gottgens, B.°: Decoding the regulatory network of early blood development from single-cell gene expression
measurements. Nat. Biotechnol. 33, 269-276 (2015)
Mook-Kanamori, D.O.°, de Mutsert, R., Rensen, P.C., Prehn, C., Adamski, J., Heijer, M.D., le Cessie, S.,
Suhre, K., Rosendaal, F.R., van Dijk, K.W.: Type 2 diabetes is associated with postprandial amino acid
measures. Arch. Biochem. Biophys. 589, 138-144 (2015)
Mook-Kanamori, M.J., El-Din Selim, M.M., Takiddin, A.H., Al-Mahmoud, K.A.S., Al-Homsi, H., McKeon, C., Al
Muftah, W.A., Kader, S.A., Mook-Kanamori, D.O., Suhre, K.°: Elevated HbA1c levels in individuals not
diagnosed with type 2 diabetes in Qatar: A pilot study. Qatar Med. J. 2014:17 (2014)
Morath, V., Truong, D.J.J., Albrecht, F., Polte, I., Ciccone, R.A., Funke, L.F., Reichart, L., Wolf, C.G.,
Brunner, A.D., Fischer, K., Schneider, P.C., Brüggenthies, J.B., Fröhlich, F., Wiedemann, G., Reski, R.,
Skerra, A.°: Design and characterization of a modular membrane protein anchor to functionalize the moss
Physcomitrella patens with extracellular catalytic and/or binding activities. ACS Synth. Biol. 3, 990-994
(2014)
Morgen, M., Jöst, C., Malz, M., Janowski, R., Niessing, D., Klein, C.D., Gunkel, N., Miller, A.K.°:
Spiroepoxytriazoles are fumagillin-like irreversible inhibitors of MetAP2 with potent cellular activityγ. ACS
Chem. Biol., DOI: 10.1021/acschembio.5b00755 (2015)
Müller, G.°, Wellmann, J., Hartwig, S., Greiser, K.H., Moebus, S., Jöckel, K.-H., Schipf, S., Völzke, H., Maier,
W., Meisinger, C., Tamayo, T., Rathmann, W., Berger, K.: Association of neighbourhood unemployment rate
with incident type 2 diabetes mellitus in five German regions. Diabet. Med. 32, 1017-1022 (2015)
Müller, J.°, Jiang, H.: Graphical limit sets for general cellular automata. Theor. Comput. Sci. 580, 14-27
(2015)
Müller, L., Jakobi, G., Czech, H., Stengel, B., Orasche, J., Arteaga-Salas, J.M., Karg, E.W., Elsasser, M.,
Sippula, O., Streibel, T., Slowik, J.G., Prevot, A.S.H., Jokiniemi, J., Rabe, R., Harndorf, H., Michalke, B.,
Schnelle-Kreis, J.°, Zimmermann, R.°: Characteristics and temporal evolution of particulate emissions from
a ship diesel engine. Appl. Energy 155, 204-217 (2015)
Müller, L., Jakobi, G., Orasche, J., Karg, E.W., Sklorz, M., Abbaszade, G., Weggler, B.A., Jing, L.,
Schnelle-Kreis, J.°, Zimmermann, R.: Online determination of polycyclic aromatic hydrocarbon formation
from a flame soot generator. Anal. Bioanal. Chem. 407, 5911-5922 (2015)
page 172 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Müller, S., Raulefs, S., Bruns, P., Afonso-Grunz, F., Plötner, A., Thermann, R., Jager, C., Schlitter, A.M.,
Kong, B., Regel, I., Roth, W.K., Rotter, B., Hoffmeier, K., Kahl, G.F., Koch, I., Theis, F.J., Kleeff, J., Winter,
P., Michalski, C.W.°: Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs,
miRNAs, sdRNAs and a piRNA in pancreatic cancer. Mol. Cancer 14:94 (2015)
Münch, K.M., Müller, J., Wienecke, S., Bergmann, S., Heyber, S., Biedendieck, R., Münch, R.°, Jahn, D.:
Polar fixation of plasmids during recombinant protein production in Bacillus megaterium results in population
heterogeneity. Appl. Environ. Microbiol. 81, 5976-5986 (2015)
Nahrendorf, M.°, Frantz, S., Swirski, F.K., Mulder, W.J., Randolph, G.J., Ertl, G., Ntziachristos, V., Piek,
J.J., Stroes, E.S., Schwaiger, M., Mann, D.L., Fayad, Z.A.: Imaging systemic inflammatory networks in
ischemic heart disease. J. Am. Coll. Cardiol. 65, 1583-1591 (2015)
Nizami, B., Tetko, I.V., Koorbanally, N.A., Honarparvar, B.°: QSAR models and scaffold-based analysis of
non-nucleoside HIV RT inhibitors. Chemometr. Intell. Lab. Syst. 148, 134-144 (2015)
Nozière, B.°, Kalberer, M.°, Claeys, M.°, Allan, J., D'Anna, B., Decesari, S., Finessi, E., Glasius, M., Grgić, I.,
Hamilton, J.F., Hoffmann, T., Iinuma, Y., Jaoui, M., Kahnt, A., Kampf, C.J., Kourtchev, I., Maenhaut, W.,
Marsden, N., Saarikoski, S., Schnelle-Kreis, J., Surratt, J.D., Szidat, S., Szmigielski, R., Wisthaler, A.: The
molecular identification of organic compounds in the atmosphere: State of the art and challenges. Chem.
Rev. 115, 3919-3983 (2015)
Obermaier, J., Stavropoulou, F.: Generalized polynomial chaos expansions with weights. J. Comput. Anal.
Appl. 18, 30-45 (2015)
Ocone, A., Haghverdi, L., Müller, N.S., Theis, F.J.°: Reconstructing gene regulatory dynamics from
high-dimensional single-cell snapshot data. Bioinformatics 31, i89-i96 (2015)
Oeder, S.#, Kanashova, T.#, Sippula, O.#, Sapcariu, S.C.#, Streibel, T.#, Arteaga-Salas, J.M.#, Passig, J.#,
Dilger, M., Paur, H.R., Schläger, C., Mülhopt, S., Diabaté, S., Weiss, C., Stengel, B., Rabe, R., Harndorf, H.,
Torvela, T., Jokiniemi, J.K., Hirvonen, M.R., Schmidt-Weber, C.B., Traidl-Hoffmann, C., BéruBé, K.A.,
Wlodarczyk, A.J., Prytherch, Z., Michalke, B., Krebs, T., Prévôt, A.S., Kelbg, M., Tiggesbäumker, J., Karg,
E.W., Jakobi, G., Scholtes, S., Schnelle-Kreis, J., Lintelmann, J., Matuschek, G., Sklorz, M., Klingbeil,
S., Orasche, J., Richthammer, P., Müller, L., Elsasser, M., Reda, A., Gröger, T.M., Weggler, B.A.,
Schwemer, T., Czech, H., Rüger, C.P., Abbaszade, G., Radischat, C., Hiller, K., Buters, J.T.M., Dittmar, G.,
Zimmermann, R.°: Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show
strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions. PLoS
ONE 10:e0126536 (2015)
Oetjen, J., Veselkov, K., Watrous, J., McKenzie, J.S., Becker, M., Hauberg-Lotte, L., Kobarg, J.H.,
Strittmatter, N., Mróz, A.K., Hoffmann, F., Trede, D., Palmer, A., Schiffler, S., Steinhorst, K., Aichler, M.,
Goldin, R., Guntinas-Lichius, O., von Eggeling, F., Thiele, H., Maedler, K., Walch, A.K., Maass, P.,
Dorrestein, P.C., Takats, Z., Alexandrov, T.°: Benchmark datasets for 3D MALDI- and DESI-imaging mass
spectrometry. GigaScience 4:20 (2015)
page 173 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Omar, M., Soliman, D., Gateau, J., Ntziachristos, V.°: High-resolution epi-illumination raster-scan
optoacoustic mesoscopy for imaging of model organisms and microvessels. Proc. SPIE 9539:95390U (2015)
Omar, M., Schwarz, M., Soliman, D., Symvoulidis, P., Ntziachristos, V.°: Pushing the optical Imaging
limits of cancer with multi-frequency-band Raster-Scan Optoacoustic Mesoscopy (RSOM). Neoplasia 17,
208-214 (2015)
Omar, M.°, Soliman, D., Gateau, J., Ntziachristos, V.: Retrieving small features in reflection-mode
Raster-Scan Optoacoustic Mesoscopy (RSOM) using multi-frequency reconstruction. Proc. SPIE
9323:932326 (2015)
Orabi, A., Bieringer, M., Geerlof, A., Bruss, V.°: An aptamer against the matrix binding domain on the
hepatitis B virus capsid impairs virion formation. J. Virol. 89, 9281-9287 (2015)
Otto, S., Streibel, T.°, Erdmann, S., Sklorz, M., Schulz-Bull, D., Zimmermann, R.: Application of
pyrolysis-mass spectrometry and pyrolysis-gas chromatography-mass spectrometry with electron-ionization
or resonance-enhanced-multi-photon ionization for characterization of crude oils. Anal. Chim. Acta 855,
60-69 (2015)
Otto, S., Streibel, T.°, Erdmann, S., Klingbeil, S., Schulz-Bull, D., Zimmermann, R.: Pyrolysis-gas
chromatography-mass spectrometry with electron-ionization or resonance-enhanced-multi-photon-ionization
for characterization of polycyclic aromatic hydrocarbons in the Baltic Sea. Mar. Pollut. Bull. 99, 35-42 (2015)
Pang, G.A., Bay, E., Dean-Ben, X.L., Razansky, D.°: Optoacoustic monitoring of real-time lesion formation
during radiofrequency catheter ablation. Proc. SPIE 9323:932308 (2015)
Pedata, P., Stöger, T.°, Zimmermann, R., Peters, A., Oberdörster, G., D'Anna, A.: "Are we forgetting the
smallest, sub 10 nm combustion generated particles?" Part. Fibre Toxicol. 12:34 (2015)
Pérez-Velázquez, J.°, Quinones, P.A.°, Hense, B.A.°, Kuttler, C.°: A mathematical model to investigate
quorum sensing regulation and its heterogeneity in Pseudomonas syringae on leaves. Ecol. Complex. 21,
128-141 (2015)
Peter, L., Pauly, O., Chatelain, P., Mateus, D., Navab, N.°: Scale-adaptive forest training via an efficient
feature sampling scheme. Lecture Notes Comp. Sci. 9349, 637-644 (2015)
Petri, T., Altmann, S., Geistlinger, L., Zimmer, R., Küffner, R.°: Addressing false discoveries in network
inference. Bioinformatics 31, 2836-2843 (2015)
page 174 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Peyrot, W.J.°, Lee, S.H., Milaneschi, Y., Abdellaoui, A., Byrne, E.M., Esko, T., de Geus, E.J., Hemani, G.,
Hottenga, J.J., Kloiber, S., Levinson, D.F., Lucae, S., Psychiatric GWAS Consortium Major Depressive
Disorder Working Group (Wray, N.R.), Martin, N.G., Medland, S.E., Metspalu, A., Milani, L., Noethen, M.M.,
Potash, J.B., Rietschel, M., Rietveld, C.A., Ripke, S., Shi, J., Social Science Genetic Association Consortium
(Gieger, C., Holle, R., Illig, T., Lichtner, P., Mielck, A., Wichmann, H.-E.), Willemsen, G., Zhu, Z.,
Boomsma, D.I., Penninx, B.: The association between lower educational attainment and depression owing to
shared genetic effects? Results in ~25 000 subjects. Mol. Psychiatry 20, 735-743 (2015)
Pfannmüller, A., Wagner, D., Sieber, C.M.K., Schönig, B., Boeckstaens, M., Marini, A.M., Tudzynski, B.°:
The general amino acid permease FfGap1 of Fusarium fujikuroi Is sorted to the vacuole in a
nitrogen-dependent, but Npr1 kinase-independent manner. PLoS ONE 10:e0125487 (2015)
Pfluger, P.T., Kabra, D.G., Aichler, M., Schriever, S.C., Pfuhlmann, K., Casquero García, V., Lehti, M.,
Weber, J., Kutschke, M., Rozman, J., Elrod, J.W., Hevener, A.L., Feuchtinger, A., Hrabě de Angelis, M.,
Walch, A.K., Rollmann, S.M., Aronow, B.J., Müller, T.D., Perez-Tilve, D., Jastroch, M., de Luca, M.,
Molkentin, J.D., Tschöp, M.H.°: Calcineurin links mitochondrial elongation with energy metabolism. Cell
Metab. 22, 838-850 (2015)
Pirovano, A.°, Brandmaier, S., Huijbregts, M.A., Ragas, A.M., Veltman, K., Hendriks, A.J.: The utilisation of
structural descriptors to predict metabolic constants of xenobiotics in mammals. Environ. Toxicol. Pharmacol.
39, 247-258 (2015)
Plant, C.°: Metric factorization for exploratory analysis of complex data. In: Kumar, R., Toivonen, H., Pei, J.,
Huang, J.Z., Wu, X. [Ed.]: (IEEE International Conference on Data Mining (ICDM)). 2014, 510-519
Plößnig, M.°, Kabak, Y., Lamprinos, I., Pabst, A., Hildebrand, C., Mantwill, S.: EMPOWER - pathways for
supporting the self-management of diabetes patients. Stud. Health Technol. Inform. 212, 159-166 (2015)
Popovic, N.°, Marr, C., Swain, P.S.: A geometric analysis of fast-slow models for stochastic gene
expression. J. Math. Biol. 72, 87-122 (2015)
Porras, P.°, Duesbury, M., Fabregat, A., Ueffing, M., Orchard, S., Gloeckner, C.J.°, Hermjakob, H.: A visual
review of the interactome of LRRK2: Using deep-curated molecular interaction data to represent biology.
Proteomics 15, 1390-1404 (2015)
Prade, E., Bittner, H.J., Sarkar, R., Lopez del Amo, J.M., Althoff-Ospelt, G., Multhaup, G., Hildebrand, P.W.,
Reif, B.°: Structural mechanism of the interaction of Alzheimer's disease Aβ fibrils with the NSAID sulindac
sulfide. J. Biol. Chem. 290, 28737-28745 (2015)
Prakash, J., Todd, N., Yalavarthy, P.K.: Prior image based temporally constrained reconstruction algorithm
for magnetic resonance guided high intensity focused ultrasound. Med. Phys. 42, 6804-6814 (2015)
Preusse, M., Marr, C., Saunders, S., Maticzka, D., Lickert, H., Backofen, R., Theis, F.J.°: SimiRa: A tool to
identify coregulation between microRNAs and RNA-binding proteins. RNA Biol. 12, 998-1009 (2015)
page 175 of 213
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HMGU authors are given in bold letters
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Radischat, C., Sippula, O., Stengel, B., Klingbeil, S., Sklorz, M., Rabe, R., Streibel, T.°, Harndorf, H.,
Zimmermann, R.: Real-time analysis of organic compounds in ship engine aerosol emissions using
resonance-enhanced multiphoton ionisation and proton transfer mass spectrometry. Anal. Bioanal. Chem.
407, 5939-5951 (2015)
Radrich, K., Ntziachristos, V.°: Quantitative multi-spectral oxygen saturation measurements independent of
tissue optical properties. J. Biophotonics 9, 83-99 (2015)
Raffler, J., Friedrich, N., Arnold, M., Kacprowski, T., Rueedi, R., Altmaier, E.M., Bergmann, S., Budde, K.,
Gieger, C., Homuth, G., Pietzner, M., Römisch-Margl, W., Strauch, K., Völzke, H., Waldenberger, M.,
Wallaschofski, H., Nauck, M., Völker, U., Kastenmüller, G.°, Suhre, K.: Genome-wide association study
with targeted and non-targeted NMR metabolomics identifies 15 novel loci of urinary human metabolic
individuality. PLoS Genet. 11:e1005487 (2015)
Raue, A.°, Steiert, B., Schelker, M., Kreutz, C., Maiwald, T., Hass, H., Vanlier, J., Tönsing, C., Adlung, L.,
Engesser, R., Mader, W., Heinemann, T., Hasenauer, J., Schilling, M., Höfer, T., Klipp, E., Theis, F.J.,
Klingmüller, U., Schöberl, B., Timmer, J.: Data2Dynamics: A modeling environment tailored to parameter
estimation in dynamical systems. Bioinformatics 31, 3558-3560 (2015)
Reagan, A.°, Gu, X.°, Hauck, S.M.°, Ash, J.D.°, Cao, G.°, Thompson, T.C.°, Elliott, M.H.°: Retinal caveolin-1
modulates neuroprotective signaling. Adv. Exp. Med. Biol. 854, 411-418 (2016)
Reda, A., Czech, H., Schnelle-Kreis, J.°, Sippula, O., Orasche, J., Weggler, B.A., Abbaszade, G.,
Arteaga-Salas, J.M., Kortelainen, M., Tissari, J., Jokiniemi, J., Streibel, T., Zimmermann, R.: Analysis of
gas-phase carbonyl compounds in emissions from modern wood combustion appliances: Influence of wood
type and combustion appliance. Energy Fuels 29, 3897-3907 (2015)
Riebold, M., Kozany, C., Freiburger, L., Sattler, M., Buchfelder, M., Hausch, F., Stalla, G.K., Paez-Pereda,
M.°: A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of
Cushing disease. Nat. Med. 21, 276-280 (2015)
Rieke, N., Hennersperger, C., Mateus, D., Navab, N.A.: Ultrasound interactive segmentation with
tensor-graph methods. In: (IEEE International Symposium on Biomedical Imaging, ISBI). Piscataway, NJ:
IEEE, 2014, 690-693
Ripoll, J., Koberstein-Schwarz, B., Ntziachristos, V.°: Unleashing optics and optoacoustics for
developmental biology. Trends Biotechnol. 33, 679-691 (2015)
Röhl, A., Tippel, F., Bender, E., Schmid, A.B., Richter, K., Madl, T., Buchner, J.°: Hop/Sti1 phosphorylation
inhibits its co-chaperone function. EMBO Rep. 16, 240-249 (2014)
Röhl, A., Wengler, D., Madl, T., Lagleder, S., Tippel, F., Herrmann, M., Hendrix, J., Richter, K., Hack, G.,
Schmid, A.B., Kessler, H., Lamb, D.C.°, Buchner, J.°: Hsp90 regulates the dynamics of its cochaperone Sti1
and the transfer of Hsp70 between modules. Nat. Commun. 6:6655 (2015)
page 176 of 213
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#
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Rückert, I.-M.°, Baumert, J.J., Schunk, M., Holle, R., Schipf, S., Völzke, H., Kluttig, A., Greiser, K.H.,
Tamayo, T., Rathmann, W., Meisinger, C.: Blood pressure control has improved in people with and without
type 2 diabetes but remains suboptimal: A longitudinal study based on the German DIAB-CORE consortium.
PLoS ONE 10:e0133493 (2015)
Rüger, C.P., Sklorz, M.°, Schwemer, T., Zimmermann, R.: Characterisation of ship diesel primary
particulate matter at the molecular level by means of ultra-high-resolution mass spectrometry coupled to
laser desorption ionisation - comparison of feed fuel, filter extracts and direct particle measurements. Anal.
Bioanal. Chem. 407, 5923-5937 (2015)
Rüger, C.P., Miersch, T., Schwemer, T., Sklorz, M.°, Zimmermann, R.: Hyphenation of thermal analysis to
ultra-high resolution Mass Spectrometry (FT-ICR MS) using Atmospheric Pressure Chemical Ionization
(APCI) for studying composition and thermal degradation of complex materials. Anal. Chem. 87, 6493–6499
(2015)
Rybacka, A.°, Rudén, C., Tetko, I.V., Andersson, P.L.: Identifying potential endocrine disruptors among
industrial chemicals and their metabolites - development and evaluation of in silico tools. Chemosphere 139,
372-378 (2015)
Sadic, D., Schmidt, K., Groh, S., Kondofersky, I., Ellwart, J.W., Fuchs, C., Theis, F.J., Schotta, G.°: Atrx
promotes heterochromatin formation at retrotransposons. EMBO Rep. 16, 836-850 (2015)
Sarkar, R., Rodriguez Camargo, D.C., Pintacuda, G., Reif, B.°: Restoring resolution in biological solid-state
NMR under conditions of off-magic-angle spinning. J. Phys. Chem. Lett. 6, 5040-5044 (2015)
Sass, S.°, Pitea, A.°, Unger, K., Hess, J., Müller, N.S., Theis, F.J.°: MicroRNA-target network inference
and local network enrichment analysis identify two microRNA clusters with distinct functions in head and
neck squamous cell carcinoma. Int. J. Mol. Sci. 16, 30204-30222 (2015)
Schäfer, A., Neschen, S., Kahle, M., Sarioglu, H., Gaisbauer, T., Imhof, A., Adamski, J., Hauck, S.M.°,
Ueffing, M.: The epoxyeicosatrienoic acid pathway enhances hepatic insulin signaling and is repressed in
insulin-resistant mouse liver. Mol. Cell. Proteomics 14, 2764-2774 (2015)
Scherb, H.°, Voigt, K., Kusmierz, R.: Ionizing radiation and the human gender proportion at birth - a
concise review of the literature and complementary analyses of historical and recent data. Early Hum. Dev.
91, 841-850 (2015)
Scherb, H.°, Kusmierz, R.°, Sigler, M.°, Voigt, K.°: Modeling human genetic radiation risks around nuclear
facilities in Germany and five neighboring countries: A sex ratio study. Environ. Modell. Softw. 79, 343-353
(2016) [published online 2015]
Schmidt, J., Panzilius, E., Bartsch, H.S., Irmler, M., Beckers, J., Kari, V., Linnemann, J., Dragoi, D.,
Hirschi, B., Kloos, U., Sass, S., Theis, F.J., Kahlert, S., Johnsen, S.A., Sotlar, K., Scheel, C.°:
Stem-cell-like properties and epithelial plasticity arise as stable traits after transient Twist1 activation. Cell
Rep. 10, 131-139 (2015)
page 177 of 213
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#
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° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Schmitt, S., Eberhagen, C., Weber, S., Aichler, M., Zischka, H.°: Isolation of mitochondria from cultured
cells and liver tissue biopsies for molecular and biochemical analyses. Methods Mol. Biol. 1295, 87-97
(2015)
Schott, K., Hunger, M., Lampert, T., Spengler, S., Mess, F., Mielck, A.°: Soziale Unterschiede in der
körperlich-sportlichen Aktivität bei Jugendlichen: Analyse der MoMo-Daten mithilfe der metabolischen
Äquivalente (MET). Gesundheitswesen, DOI: 10.1055/s-0034-1398556 (2015)
Schremser, K.°, Rogowski, W.H., Adler-Reichel, S., Tufman, A.L., Huber, R.M., Stollenwerk, B.:
Cost-effectiveness of an individualized first-line treatment strategy offering erlotinib based on EGFR mutation
testing in advanced lung adenocarcinoma patients in Germany. Pharmacoeconomics 33, 1215-1228 (2015)
Schuler, D., Wahl, R., Wippel, K., Vranes, M., Münsterkötter, M., Sauer, N., Kämper, J.T.°: Hxt1, a
monosaccharide transporter and sensor required for virulence of the maize pathogen Ustilago maydis. New
Phytol. 206, 1086-1100 (2015)
Schulz, S., Lichtmannegger, J., Schmitt, S., Leitzinger, C., Eberhagen, C., Einer, C., Kerth, J., Aichler,
M., Zischka, H.°: A protocol for the parallel isolation of intact mitochondria from rat liver, kidney, heart, and
brain. Methods Mol. Biol. 1295, 75-86 (2015)
Schunk, M., Reitmeir, P., Schipf, S., Völzke, H., Meisinger, C., Ladwig, K.-H., Kluttig, A., Greiser, K.H.,
Berger, K.U., Müller, G., Ellert, U., Neuhauser, H., Tamayo, T., Rathmann, W., Holle, R.°: Health-related
quality of life in women and men with type 2 diabetes: A comparison across treatment groups. J. Diab.
Complic. 29, 203-211 (2015)
Schunk, M.°, Stark, R.G., Reitmeir, P., Meisinger, C., Holle, R.: Towards patient-oriented diabetes care:
Results from two KORA surveys in Southern Germany: J. Diabetes Res. 2015:368570 (2015)
Schwab, S., Zierer, A., Schneider, A.E., Heier, M., Koenig, W., Kastenmüller, G., Waldenberger, M.,
Peters, A., Thorand, B.°: Vitamin E supplementation is associated with lower levels of C-reactive protein
only in higher dosages and combined with other antioxidants: The Cooperative Health Research in the
Region of Augsburg (KORA) F4 study. Br. J. Nutr. 113, 1782-1791 (2015)
Schwarz, M., Bühler, A., Aguirre, J., Ntziachristos, V.°: Three-dimensional multispectral optoacoustic
mesoscopy reveals melanin and blood oxygenation in human skin in vivo. J. Biophotonics 9, 55-60 (2015)
Schwarz, M., Aguirre, J., Bühler, A., Omar, M., Ntziachristos, V.°: Visualization of the microcirculatory
network in skin by high frequency optoacoustic mesoscopy. Proc. SPIE 9539:95390J (2015)
Schwarzkopf, L.°, Wacker, M.°, Holle, R.°, Leidl, R.°, Günster, C.°, Adler, J.B.°, Huber, R.M.°:
Cost-components of lung cancer care within the first three years after initial diagnosis in context of different
treatment regimens. Lung Cancer 90, 274-280 (2015)
page 178 of 213
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#
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° corresponding authors
HMGU authors are given in bold letters
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Scialdone, A.°, Natarajan, K.N., Saraiva, L.R., Proserpio, V., Teichmann, S.A., Stegle, O.°, Marioni, J.C.°,
Buettner, F.°: Computational assignment of cell-cycle stage from single-cell transcriptome data. Methods
85, 54-61 (2015)
Sekula, P., Goek, O.N., Quaye, L., Barrios, C., Levey, A.S., Römisch-Margl, W., Menni, C., Yet, I., Gieger,
C., Inker, L.A., Adamski, J., Gronwald, W., Illig, T., Dettmer, K., Krumsiek, J., Oefner, P.J., Valdes, A.M.,
Meisinger, C., Coresh, J., Spector, T.D., Mohney, R.P., Suhre, K., Kastenmüller, G.°, Köttgen, A.°: A
metabolome-wide association study of kidney function and disease in the general population. J. Am. Soc.
Nephrol. 27, 1175-1188 (2016) [published online 2015]
Sena, F.V., Batista, A.P., Catarino, T., Brito, J.A., Archer, M., Viertler, M., Madl, T., Cabrita, E.J., Pereira,
M.M.°: Type-II NADH:quinone oxidoreductase from Staphylococcus aureus has two distinct binding sites and
is rate limited by quinone reduction. Mol. Microbiol. 98, 272-288 (2015)
Severin, F.°, Stollenwerk, B., Holinski-Feder, E., Meyer, E., Heinemann, V., Giessen-Jung, C., Rogowski,
W.H.: Economic evaluation of genetic screening for Lynch syndrome in Germany. Genet. Med. 17, 765-773
(2015)
Shariful Islam, S.M.°, Lechner, A., Ferrari, U., Seissler, J., Holle, R., Niessen, L.W.: Mobile phone use and
willingness to pay for SMS for diabetes in Bangladesh. J. Public Health 38, 163-169 (2016) [published online
2015]
Sim, N., Gottschalk, S., Pal, R., Delbianco, M., Degtyaruk, O., Razansky, D., Westmeyer, G.G.,
Ntziachristos, V., Parker, D., Mishra, A.°: Wavelength-dependent optoacoustic imaging probes for NMDA
receptor visualisation. Chem. Commun. 51, 15149-15152 (2015)
Sirko, S., Irmler, M., Gascón, S., Bek, S., Schneider, S., Dimou, L., Obermann, J., de Souza Paiva, D.,
Poirier, F., Beckers, J., Hauck, S.M., Barde, Y.A., Götz, M.°: Astrocyte reactivity after brain injury - the role
of galectins 1 and 3. Glia 63, 2340-2361 (2015)
Skiöld, S., Azimzadeh, O., Merl-Pham, J., Näslund, I., Wersäll, P.J., Lidbrink, E.K., Tapio, S.,
Harms-Ringdahl, M., Haghdoost, S.°: Unique proteomic signature for radiation sensitive patients: A
comparative study between normo-sensitive and radiation sensitive breast cancer patients. Mutat. Res.
-Fund. Mol. Mech. Mutag. 776, 128-135 (2015)
Smit, E.°, Rüger, C.P., Sklorz, M., de Goede, S., Zimmermann, R., Rohwer, E.R.: Investigating the trace
polar species present in diesel using high-resolution mass spectrometry and selective ionization techniques.
Energy Fuels 29, 5554-5562 (2015)
Sokolenko, A.P., Suspitsin, E.N., Kuligina, E.S., Bizin, I.V., Frishman, D., Imyanitov, E.N.°: Identification of
novel hereditary cancer genes by whole exome sequencing. Cancer Lett. 369, 274-288 (2015)
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Soliman, D. , Tserevelakis, G.J. , Omar, M., Ntziachristos, V.°: Combining microscopy with mesoscopy
using optical and optoacoustic label-free modes. Sci. Rep. 5:12902 (2015)
page 179 of 213
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joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Soliman, D., Tserevelakis, G.J., Omar, M., Ntziachristos, V.°: Hybrid label-free Multiphoton and
Optoacoustic Microscopy (MPOM). Proc. SPIE 9539:953908 (2015)
Sonner, S., Efendiyev, M.A., Eberl, H.J.°: On the well-posedness of mathematical models for
multicomponent biofilms. Math. Meth. Appl. Sci. 38, 3753–3775 (2015)
Stiel, A.C., Dean-Ben, X.L., Jiang, Y., Ntziachristos, V., Razansky, D., Westmeyer, G.G.°: High-contrast
imaging of reversibly switchable fluorescent proteins via temporally unmixed multispectral optoacoustic
tomography. Opt. Lett. 40, 367-370 (2015)
Stollenwerk, B.°, Bartmus, T., Klug, F., Stock, S., Müller, D.: Cost-effectiveness of hip protector use on a
geriatric ward in Germany: A Markov model. Osteoporos. Int. 26, 1367-1379 (2015)
Stollenwerk, B.°, Welchowski, T., Vogl, M., Stock, S.: Cost-of-illness studies based on massive data: A
prevalence-based, top-down regression approach. Eur. J. Health Econ. 17, 235-244 (2016) [published online
2015]
Storath, M.°, Demaret, L., Massopust, P.: Signal analysis based on complex wavelet signs. Appl. Comput.
Harmon. Anal., DOI: 10.1016/j.acha.2015.08.005 (2014)
Strasser, M., Feigelman, J., Theis, F.J., Marr, C.°: Inference of spatiotemporal effects on cellular state
transitions from time-lapse microscopy. BMC Syst. Biol. 9:61 (2015)
Strobl, A.N.°, Vickers, A.J., van Calster, B., Steyerberg, E., Leach, R.J., Thompson, I.M., Ankerst, D.P.:
Improving patient prostate cancer risk assessment: Moving from static, cross mark globally-applied to
dynamic, practice-specific risk calculators. J. Biomed. Inform. 56, 87-93 (2015)
Strobl, R.°, Maier, W., Ludyga, A., Mielck, A., Grill, E.: Relevance of community structures and
neighbourhood characteristics for participation of older adults: A qualitative study. Qual. Life Res. 25,
143-152 (2015)
Suhre, K., Raffler, J., Kastenmüller, G.: Biochemical insights from population studies with genetics and
metabolomics. Arch. Biochem. Biophys. 589, 168-176 (2016) [published online 2015]
Suhre, K., Schwartz, J.E., Sharma, V.K., Chen, Q., Lee, J.R., Muthukumar, T., Dadhania, D.M., Ding, R.,
Ikle, D.N., Bridges, N.D., Williams, N.M., Kastenmüller, G., Karoly, E.D., Mohney, R.P., Abecassis, M.,
Friedewald, J., Knechtle, S.J., Becker, Y.T., Samstein, B., Shaked, A., Gross, S.S., Suthanthiran, M.°: Urine
metabolite profiles predictive of human kidney allograft status. J. Am. Soc. Nephrol. 27, 626-636 (2015)
Sun, N., Fernandez, I.E., Wei, M., Wu, Y., Aichler, M., Eickelberg, O.°, Walch, A.K.°: Pharmacokinetic
and pharmacometabolomic study of pirfenidone in normal mouse tissues using high mass resolution
MALDI-FTICR-mass spectrometry imaging. Histochem. Cell Biol. 145, 201-211 (2016) [published online
2015]
page 180 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Sushko, Y.°, Novotarskyi, S., Körner, R., Vogt, J., Abdelaziz, A., Tetko, I.V.: Prediction-driven matched
molecular pairs to interpret QSARs and aid the molecular optimization process. J. Cheminformatics 6:48
(2014)
Symvoulidis, P., Cruz Perez, C., Schwaiger, M., Ntziachristos, V., Westmeyer, G.G.: Serial sectioning
and multispectral imaging system for versatile biomedical applications. In: (IEEE International Symposium
on Biomedical Imaging, ISBI). IEEE: Piscataway, NJ, 2014, 890-893
Taruttis, A., Ntziachristos, V.°: Advances in real-time multispectral optoacoustic imaging and its
applications. Nat. Photonics 9, 219-227 (2015)
Taruttis, A., van Dam, G.M., Ntziachristos, V.°: Mesoscopic and macroscopic optoacoustic imaging of
cancer. Cancer Res. 75, 1548-1559 (2015)
#
#
Teiluf, K. , Seidl, C. , Blechert, B., Gaertner, F.C., Gilbertz, K.P., Fernandez, V., Bassermann, F., Endell, J.,
Boxhammer, R., Leclair, S., Vallon, M., Aichler, M., Feuchtinger, A., Bruchertseifer, F., Morgenstern, A.,
Essler, M.°: α-Radioimmunotherapy with 213Bi-anti-CD38 immunoconjugates is effective in a mouse model
of human multiple myeloma. Oncotarget 6, 4692-4703 (2015)
Teuner, C.M., John, J., Wolfenstetter, S.B., Holle, R.°: An economic perspective on childhood obesity.
Pediatr. Adolesc. Med. 19, 148-159 (2015)
Tharun, I.M., Nieto, L., Haase, C., Scheepstra, M., Balk, M., Möcklinghoff, S., Adriaens, W., Dames, S.A.,
Brunsveld, L.°: Subtype-specific modulation of estrogen receptor-coactivator interaction by phosphorylation.
ACS Chem. Biol. 10, 475-484 (2015)
Theis, F.J.°, Ugelvig, L.V.°, Marr, C.°, Cremer, S.°: Opposing effects of allogrooming on disease
transmission in ant societies. Philos. Trans. R. Soc. B - Biol. Sci. 370, DOI: 10.1098/rstb.2014.0108 (2015)
Thiele, I.°, Linseisen, J., Meisinger, C., Schwab, S., Huth, C., Peters, A., Perz, S., Meitinger, T.,
Kronenberg, F., Lamina, C., Thiery, J., Koenig, W., Rathmann, W., Kääb, S., Then, C., Seissler, J.,
Thorand, B.: Associations between calcium and vitamin D supplement use as well as their serum
concentrations and subclinical cardiovascular disease phenotypes. Atherosclerosis 241, 743-751 (2015)
Thrul, J.°, Pabst, A., Kraus, L.: The impact of school nonresponse on substance use prevalence estimates Germany as a case study. Int. J. Drug Policy 27, 164-172 (2015)
#
#
Tsang, J.C.H. , Yu, Y. , Burke, S., Buettner, F., Wang, C., Kolodziejczyk, A.A., Teichmann, S.A., Lu, L., Liu,
P.°: Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in
Bcl11a-deficient hematopoietic stem cells. Genome Biol. 16:178 (2015)
Tsepilov, Y.A., Shin, S.Y., Soranzo, N., Spector, T.D., Prehn, C., Adamski, J., Kastenmüller, G.,
Wang-Sattler, R., Strauch, K., Gieger, C., Aulchenko, Y.S., Ried, J.S.°: Non-additive effects of genes in
human metabolomics. Genetics 200, 707-718 (2015)
page 181 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Uhl, P.B., Amann, B., Hauck, S.M., Deeg, C.A.°: Novel localization of peripherin 2, the
photoreceptor-specific retinal degeneration slow protein, in retinal pigment epithelium. Int. J. Mol. Sci. 16,
2678-2692 (2015)
Uksa, M., Schloter, M.°, Endesfelder, D., Kublik, S., Engel, M., Kautz, T., Köpke, U., Fischer, D.:
Prokaryotes in subsoil - evidence for a strong spatial separation of different phyla by analysing
co-occurrence networks. Front. Microbiol. 6:1269 (2015)
Velikova, V.B., Müller, C., Ghirardo, A., Rock, T., Aichler, M., Walch, A.K., Schmitt-Kopplin, P.,
Schnitzler, J.-P.°: Knocking down of isoprene emission modifies the lipid matrix of thylakoid membranes
and influences the chloroplast ultrastructure in poplar. Plant Physiol. 168, 859-870 (2015)
Vogl, M.°, Leidl, R.: Informing management on the future structure of hospital care: An extrapolation of
trends in demand and costs in lung diseases. Eur. J. Health Econ., DOI: 10.1007/s10198-015-0699-4 (2015)
Vogt, S., Zierer, A., Laxy, M., Koenig, W., Linkohr, B., Linseisen, J., Peters, A., Thorand, B.°:
Association of serum vitamin D with change in weight and total body fat in a German cohort of older adults.
Eur. J. Clin. Nutr. 70, 136-139 (2016) [published online 2015]
Vogt, S.°, Mielck, A., Berger, U., Grill, E., Peters, A., Döring, A., Holle, R., Strobl, R., Zimmermann, A.-K.,
Linkohr, B., Wolf, K., Kneißl, K., Maier, W.: Neighborhood and healthy aging in a German city: Distances to
green space and senior service centers and their associations with physical constitution, disability, and
health-related quality of life. Eur. J. Ageing 12, 273-283 (2015)
Voss, A.°, Schroeder, R., Heitmann, A., Peters, A., Perz, S.: Short-term heart rate variability-influence of
gender and age in healthy subjects. PLoS ONE 10:e0118308 (2015)
Wahl, S.#°, Vogt, S.#, Stückler, F., Krumsiek, J., Bartel, J., Kacprowski, T., Schramm, K., Carstensen, M.,
Rathmann, W., Roden, M., Jourdan, C., Kangas, A.J., Soininen, P., Ala-Korpela, M., Nöthlings, U., Boeing,
H., Theis, F.J., Meisinger, C., Waldenberger, M., Suhre, K., Homuth, G., Gieger, C., Kastenmüller, G.,
Illig, T., Linseisen, J., Peters, A., Prokisch, H., Herder, C., Thorand, B.°, Grallert, H.°: Multi-omic
signature of body weight change: Results from a population-based cohort study. BMC Med. 13:48 (2015)
Wang, L., Belagiannis, V., Marr, C., Theis, F.J., Yang, G.Z., Navab, N.: Anatomic-landmark detection using
graphical context modelling. In: (12th IEEE International Symposium on Biomedical Imaging, ISBI 2015).
2015, 1304-1307
Wang, X., Tang, Q., Popowicz, G.M., Yang, B., Wang, Y.°: A mechanistic study into the epoxidation of
carboxylic acid and alkene in a mono, di-acylglycerol lipase. Biochem. Biophys. Res. Commun. 460, 392-396
(2015)
Weinmann, A.°, Storath, M.: Iterative Potts and Blake-Zisserman minimization for the recovery of functions
with discontinuities from indirect measurements. Proc. R. Soc. London A 471:20140638 (2015)
page 182 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
1
Weinmann, A.°, Storath, M.°, Demaret, L.°: The L -Potts functional for robust jump-sparse reconstruction.
SIAM J. Numer. Anal. 53, 644-673 (2015)
Wheway, G.#, Schmidts, M.#, Mans, D.A.#, Szymanska, K.#, Nguyen, T.T.#, Racher, H., Phelps, I.G., Toedt,
G., Kennedy, J., Wunderlich, K.A., Sorusch, N., Abdelhamed, Z.A., Natarajan, S., Herridge, W., van
Reeuwijk, J., Horn, N., Boldt, K., Parry, D.A., Letteboer, S.J., Roosing, S., Adams, M., Bell, S.M., Bond, J.,
Higgins, J., Morrison, E.E., Tomlinson, D.C., Slaats, G.G., van Dam, T.J., Huang, L., Kessler, K., Giessl, A.,
Logan, C.V., Boyle, E.A., Shendure, J., Anazi, S., Aldahmesh, M., Al Hazzaa, S., Hegele, R.A., Ober, C.,
Frosk, P., Mhanni, A.A., Chodirker, B.N., Chudley, A.E., Lamont, R., Bernier, F.P., Beaulieu, C.L., Gordon,
P.M., Pon, R.T., Donahue, C., Barkovich, A.J., Wolf, L., Toomes, C., Thiel, C.T., Boycott, K.M., McKibbin, M.,
Inglehearn, C.F., Stewart, F., Omran, H., Huynen, M.A., Sergouniotis, P.I., Alkuraya, F.S., Parboosingh, J.S.,
Innes, A.M., Willoughby, C.E., Giles, R.H., Webster, A.R., Ueffing, M., Blacque, O.E., Gleeson, J.G.,
Wolfrum, U., Beales, P.L., Gibson, T.J., Doherty, D.°, Mitchison, H.M.°, Roepman, R.°, Johnson, C.A.°: An
siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and
ciliopathy genes. Nat. Cell Biol. 17, 1074-1087 (2015)
Widmann, P., Reverter, A., Weikard, R., Suhre, K., Hammon, H.M., Albrecht, E., Kuehn, C.°: Systems
biology analysis merging phenotype, metabolomic and genomic data identifies Non-SMC Condensin I
Complex, Subunit G (NCAPG) and cellular maintenance processes as major contributors to genetic
variability in bovine feed efficiency. PLoS ONE 10:e0124574 (2015)
Wieczorek, M.°, Frikel, J., Vogel, J., Eggl, E., Kopp, F., Noel, P.B., Pfeiffer, F., Demaret, L., Lasser, T.:
X-ray computed tomography using curvelet sparse regularization. Med. Phys. 42, 1555-1565 (2015)
#
#
Willmann, S. , Müller, N.S. , Engert, S., Sterr, M., Burtscher, I., Raducanu, A., Irmler, M., Beckers, J.,
Sass, S., Theis, F.J., Lickert, H.°: The global gene expression profile of the secondary transition during
pancreatic development. Mech. Dev. 139, 51-64 (2016) [published online 2015]
Wilson, N.K., Kent, D.G., Buettner, F., Shehata, M., Macaulay, I.C., Calero-Nieto, F.J., Sánchez Castillo, M.,
Oedekoven, C.A., Diamanti, E., Schulte, R., Ponting, C.P., Voet, T., Caldas, C., Stingl, J., Green, A.R.,
Theis, F.J., Göttgens, B.°: Combined single-cell functional and gene expression analysis resolves
heterogeneity within stem cell populations. Cell Stem Cell 16, 712-724 (2015)
Wittwer, M., Dames, S.A.°: Expression and purification of the natively disordered and redox sensitive metal
binding regions of Mycobacterium tuberculosis protein kinase G. Protein Expr. Purif. 111, 68-74 (2015)
Wohlfahrt, S., Fischer, M., Varga, J., Saraji-Bozorgzad, M.R., Matuschek, G., Denner, T., Zimmermann,
R.°: A dual-stage consumable-free thermal modulator for the hyphenation of Thermal Analysis, Gas
Chromatography and Mass Spectrometry (TA-GC-MS). Anal. Chem. 88, 640-644 (2016) [published online
2015]
page 183 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Wolf, K.°, Schneider, A.E., Breitner, S., Meisinger, C., Heier, M., Cyrys, J., Kuch, B., von Scheidt, W.,
Peters, A., KORA Study Group (Gieger, C., Grallert, H., Heinrich, J., Holle, R., Leidl, R., Strauch, K.):
Associations between short-term exposure to particulate matter and ultrafine particles and myocardial
infarction in Augsburg, Germany. Int. J. Hyg. Environ. Health 218, 535-542 (2015)
Xie, B., Stammes, M.A., van Driel, P.B., Cruz, L.J., Knol-Blankevoort, V.T., Löwik, M.A., Mezzanotte, L.,
Que, I., Chan, A., van den Wijngaard, J.P., Siebes, M., Gottschalk, S., Razansky, D., Ntziachristos, V.,
Keereweer, S., Horobin, R.W., Hoehn, M., Kaijzel, E.L., van Beek, E.R., Snoeks, T.J., Löwik, C.W.°:
Necrosis avid near infrared fluorescent cyanines for imaging cell death and their use to monitor therapeutic
efficacy in mouse tumor models. Oncotarget 6, 39036-39049 (2015)
Xu, T., Brandmaier, S., Messias, A.C., Herder, C., Draisma, H.H., Demirkan, A., Yu, Z., Ried, J.S., Haller,
T., Heier, M., Campillos, M., Fobo, G., Stark, R.G., Holzapfel, C., Adam, J., Chi, S., Rotter, M., Panni, T.,
Quante, A.S., He, Y., Prehn, C., Römisch-Margl, W., Kastenmüller, G., Willemsen, G., Pool, R., Kasa, K.,
van Dijk, K.W., Hankemeier, T., Meisinger, C., Thorand, B., Ruepp, A., Hrabě de Angelis, M., Li, Y.,
Wichmann, H.-E., Stratmann, B., Strauch, K., Metspalu, A., Gieger, C., Suhre, K., Adamski, J., Illig, T.,
Rathmann, W., Roden, M., Peters, A., van Duijn, C.M., Boomsma, D.I., Meitinger, T., Wang-Sattler, R.°:
Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes. Diabetes
Care 38, 1858-1867 (2015)
Yang, J.Z., Röwer, C., Koy, C., Ruß, M., Rüger, C.P., Zimmermann, R., Fritschen, U.V., Bredell, M., Finke,
J.C., Glocker, M.O.°: Mass spectrometric characterization of limited proteolysis activity in human plasma
samples under mild acidic conditions. Methods 89, 30-37 (2015)
Yang, Q., Boehm, C., Scholz, M., Plant, C., Shao, J.°: Predicting multiple functions of sustainable flood
retention basins under uncertainty via multi-instance multi-label learning. Water 7, 1359-1377 (2015)
Yousri, N.A., Mook-Kanamori, D.O., Selim, M.M.E.D., Takiddin, A.H., Al-Homsi, H., Al-Mahmoud, K.A.S.,
Karoly, E.D., Krumsiek, J., Do, K.T., Neumaier, U., Mook-Kanamori, M.J., Rowe, J., Chidiac, O.M.,
McKeon, C., Al Muftah, W.A., Kader, S.A., Kastenmüller, G., Suhre, K.°: A systems view of type 2
diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic
control. Diabetologia 58, 1855-1867 (2015)
Yousri, N.A., Kastenmüller, G., AlHaq, W.G., Holle, R., Kääb, S., Mohney, R.P., Gieger, C., Peters, A.,
Adamski, J., Suhre, K., Arayssi, T.°: Diagnostic and prognostic metabolites identified for joint symptoms in
the KORA population. J. Proteome Res. 15, 554-562 (2016) [published online 2015]
Yttri, K.E.°, Schnelle-Kreis, J., Maenhaut, W., Abbaszade, G., Alves, C.A., Bjerke, A., Bonnier, N., Bossi,
R., Claeys, M., Dye, C., Evtyugina, M.G., García Gacio, D., Hillamo, R.E.J., Hoffer, A.G., Hyder, M., Iinuma,
Y., Jaffrezo, J.L., Kasper-Giebl, A., Kiss, G., López-Mahía, P.L., Pio, C., Piot, C., Ramirez-Santa-Cruz, C.,
Sciare, J., Teinilä, K., Vermeylen, R., Vicente, A.M., Zimmermann, R.: An intercomparison study of
analytical methods used for quantification of levoglucosan in ambient aerosol filter samples. Atmos. Meas.
Tech. 8, 125-147 (2015)
page 184 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
New Technologies for Biomedical Discoveries
Zach, N.°, Ennist, D.L., Taylor, A.A., Alon, H., Sherman, A.V., Küffner, R., Walker, J., Sinani, E., Katsovskiy,
I., Cudkowicz, M.E., Leitner, M.L.: Being PRO-ACTive: What can a clinical trial database reveal about ALS?
Neurotherapeutics 12, 417-423 (2015)
Zaghlool, S.B., Al-Shafai, M., Al Muftah, W.A., Kumar, P., Falchi, M., Suhre, K.°: Association of DNA
methylation with age, gender, and smoking in an Arab population. Clin. Epigenet. 7:6 (2015)
Zhang, Y.°, Huang, R.J., El Haddad, I., Ho, K.F., Cao, J., Han, Y., Zotter, P., Bozzetti, C., Daellenbach, K.R.,
Canonaco, F., Slowik, J.G., Salazar, G.A., Schwikowski, M., Schnelle-Kreis, J., Abbaszade, G.,
Zimmermann, R., Baltensperger, U.R.S., Prevot, A.S.H., Szidat, S.°: Fossil vs. non-fossil sources of fine
carbonaceous aerosols in four Chinese cities during the extreme winter haze episode of 2013. Atmos. Chem.
Phys. 15, 1299-1312 (2015)
Zhang, Y.°, Schnelle-Kreis, J., Abbaszade, G., Zimmermann, R., Zotter, P., Shen, R.R., Schaefer, K.,
Shao, L., Prévôt, A.S., Szidat, S.: Source apportionment of elemental carbon in Beijing, China: Insights from
radiocarbon and organic marker measurements. Environ. Sci. Technol. 49, 8408-8415 (2015)
Zhao, F., El-Kelish, A., Durner, J., Lindermayr, C., Winkler, J.B., Rueff, F., Behrendt, H., Traidl-Hoffmann,
C., Holzinger, A., Kofler, W., Braun, P., von Toerne, C., Hauck, S.M., Ernst, D., Frank, U.°: Common
ragweed (Ambrosia artemisiifolia L.): Allergenicity and molecular characterisation of pollen after plant
exposure to elevated NO2. Plant Cell Environ. 39, 147-164 (2016) [published online 2015]
Ziegler, D., Voss, A., Rathmann, W., Strom, A., Perz, S., Roden, M., Peters, A., Meisinger, C., KORA Study
Group (Heinrich, J., Gieger, C., Grallert, H., Holle, R., Leidl, R., Strauch, K.): Increased prevalence of
cardiac autonomic dysfunction at different degrees of glucose intolerance in the general population: The
KORA S4 survey. Diabetologia 58, 1118-1128 (2015)
Zierer, J., Menni, C., Kastenmüller, G., Spector, T.D.°: Integration of 'omics' data in aging research: From
biomarkers to systems biology. Aging Cell 14, 933–944 (2015)
Zimmermann, R.°, Hertz-Schünemann, R., Ehlert, S., Liu, C., McAdam, K., Baker, R., Streibel, T.: Highly
time-resolved imaging of combustion and pyrolysis product concentrations in solid fuel combustion: NO
formation in a burning cigarette. Anal. Chem. 87, 1711-1717 (2015)
Zissler, U.M., Chaker, A.M., Effner, R., Ulrich, M., Guerth, F., Piontek, G., Dietz, K., Regn, M., Knapp, B.,
Theis, F.J., Heine, H., Suttner, K., Schmidt-Weber, C.B.°: Interleukin-4 and interferon-γ orchestrate an
epithelial polarization in the airways. Mucosal Immunol., DOI: 10.1038/mi.2015.110 (2015)
Zwirglmaier, K.°, Keiz, K., Engel, M., Geist, J., Raeder, U.: Seasonal and spatial patterns of microbial
diversity along a trophic gradient in the interconnected lakes of the Osterseen Lake District, Bavaria. Front.
Microbiol. 6:1168 (2015)
page 185 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Lung Research
Casas, L.°, Sunyer, J., Tischer, C.G., Gehring, U., Wickman, M., García-Esteban, R., Lehmann, I., Kull, I.,
Reich, A., Lau, S., Wijga, A.H., Antò, J.M., Nawrot, T.S., Heinrich, J., Keil, T.O., Torrent, M.: Early-life house
dust mite allergens, childhood mite sensitization, and respiratory outcomes. Allergy 70, 820–827 (2015)
Fernandez, I.E., Heinzelmann, K., Verleden, S., Eickelberg, O.°: Characteristic patterns in the fibrotic lung.
Comparing idiopathic pulmonary fibrosis with chronic lung allograft dysfunction. Ann. Am. Thorac. Soc. 12,
S34-S41 (2015)
Fischer, L., Arnold, M.°, Kirsch, F., Leidl, R.: Wirtschaftlichkeit des 21 Gene Tests in der Behandlung von
Patientinnen mit nodal-positivem Mammakarzinom. Gesundheitswesen, DOI: 10.1055/s-0035-1549989
(2015)
Flexeder, C., Thiering, E., von Berg, A., Berdel, D., Hoffmann, B., Koletzko, S., Bauer, C.P., Koletzko, B.,
Heinrich, J.°, Schulz, H.: Peak weight velocity in infancy is negatively associated with lung function in
adolescence. Pediatr. Pulmonol. 51, 147-156 (2016) [published online 2015]
Fuertes, E., Bracher, J., Flexeder, C., Markevych, I., Klümper, C., Hoffmann, B., Krämer, U., von Berg, A.,
Bauer, C.P., Koletzko, S., Berdel, D., Heinrich, J., Schulz, H.°: Long-term air pollution exposure and lung
function in 15 year-old adolescents living in an urban and rural area in Germany: The GINIplus and LISAplus
cohorts. Int. J. Hyg. Environ. Health 218, 656-665 (2015)
Giannou, A.D., Marazioti, A., Spella, M., Kanellakis, N.I., Apostolopoulou, H., Psallidas, L., Prijovich, Z.M.,
Vreka, M., Zazara, D.E., Lilis, L., Papaleonidopoulos, V., Kairi, C.A., Patmanidi, A.L., Giopanou, J.,
Spiropoulou, N., Harokopos, V., Aidinis, V., Spyratos, D., Teliousi, S., Papadaki, H., Taraviras, S., Snyder,
L.A., Eickelberg, O., Kardamakis, D., Iwakura, V., Feyerabend, T.B., Rodewald, H.R., Kalomenidis, L.,
Blackwell, T.S.°, Agalloti, T.°, Stathopoulos, G.T.°: Mast cells mediate malignant pleural effusion formation.
J. Clin. Invest. 125, 2317-2334 (2015)
Hellbach, K., Yaroshenko, A., Meinel, F.G., Yildirim, A.Ö., Conlon, T.M., Bech, M., Mueller, M., Velroyen,
A., Notohamiprodjo, M., Bamberg, F., Auweter, S., Reiser, M., Eickelberg, O., Pfeiffer, F.°: In vivo dark-field
radiography for early diagnosis and staging of pulmonary emphysema. Invest. Radiol. 50, 430-435 (2015)
Huber, M.B.°, Wacker, M., Vogelmeier, C.F., Leidl, R.: Comorbid influences on generic health-related
quality of life in COPD: A systematic review. PLoS ONE 10:e0132670 (2015)
Huber, M.B.°, Wacker, M., Vogelmeier, C.F., Leidl, R.: Excess costs of comorbidities in chronic obstructive
pulmonary disease: A systematic review. PLoS ONE 10:e0123292 (2015)
John-Schuster, G.°, Günter, S., Hager, K., Conlon, T.M., Eickelberg, O., Yildirim, A.Ö.°: Inflammaging
increases susceptibility to cigarette smoke-induced COPD. Oncotarget, DOI: 10.18632/oncotarget.4027
(2015)
Karo-Atar, D., Bordowitz, A., Wand, O., Pasmanik-Chor, M., Fernandez, I.E., Itan, M., Frenkel, R., Herbert,
D.R., Finkelman, F.D., Eickelberg, O., Munitz, A.°: A protective role for IL-13 receptor α 1 in
bleomycin-induced pulmonary injury and repair. Mucosal Immunol. 9, 240-253 (2016) [published online 2015]
page 186 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Lung Research
Kirsch, F.°: A systematic review of quality and cost-effectiveness derived from Markov models evaluating
smoking cessation interventions in patients with chronic obstructive pulmonary disease. Expert Rev.
Pharmacoecon. Outcomes Res. 15, 301-316 (2015)
Krämer, U.°, Schmitz, R., Ring, J., Behrendt, H.°: What can reunification of East and West Germany tell us
about the cause of the allergy epidemic? Clin. Exp. Allergy 45, 94-107 (2014)
Kreuter, M.°, Herth, F., Wacker, M., Leidl, R., Hellmann, A., Pfeifer, M., Behr, J., Witt, S., Kauschka, D.,
Mall, M., Günther, A., Markart, P.: Exploring clinical and epidemiological characteristics of interstitial lung
diseases: Rationale, aims, and design of a nationwide prospective registry - the EXCITING-ILD registry.
Biomed Res. Int. 2015:123876 (2015)
Luzak, A., Flexeder, C., von Berg, A., Berdel, D., Klümper, C., Koletzko, S., Bauer, C.P., Heinrich, J.,
Nowak, D., Schulz, H.°: Relation of lung function and current inhalant allergen-specific immunoglobulin E
concentrations in adolescents (GINIplus cohort). Ann. Allerg. Asthma Immunol. 115, 183-190 (2015)
Obeidat, M., Hao, K., Bossé, Y., Nickle, D.C., Nie, Y., Postma, D.S., Laviolette, M., Sandford, A.J., Daley,
D.D., Hogg, J.C., Elliott, W.M., Fishbane, N., Timens, W., Hysi, P.G., Kaprio, J., Wilson, J.F., Hui, J., Rawal,
R., Schulz, H., Stubbe, B., Hayward, C., Polasek, O., Jarvelin, M.R., Zhao, J.H., Jarvis, D., Kähönen, M.,
Franceschini, N., North, K.E., Loth, D.W., Brusselle, G.G., Smith, A.V., Gudnason, V., Bartz, T.M., Wilk, J.B.,
O'Connor, G.T., Cassano, P.A., Tang, W., Wain, L.V., Artigas, M.S., Gharib, S.A., Strachan, D.P., Sin, D.D.,
Tobin, M.D., London, S.J., Hall, I.P., Paré, P.D.°: Molecular mechanisms underlying variations in lung
function: A systems genetics analysis. Lancet Resp. Med. 3, 782-795 (2015)
Schiller, H.°, Fernandez, I.E., Burgstaller, G., Schaab, C., Scheltema, R.A., Schwarzmayr, T., Strom,
T.M., Eickelberg, O.°, Mann, M.°: Time- and compartment-resolved proteome profiling of the extracellular
niche in lung injury and repair. Mol. Syst. Biol. 11:819 (2015)
Schremser, K.°, Rogowski, W.H., Adler-Reichel, S., Tufman, A.L., Huber, R.M., Stollenwerk, B.:
Cost-effectiveness of an individualized first-line treatment strategy offering erlotinib based on EGFR mutation
testing in advanced lung adenocarcinoma patients in Germany. Pharmacoeconomics 33, 1215-1228 (2015)
Schwarzkopf, L.°, Wacker, M.°, Holle, R.°, Leidl, R.°, Günster, C.°, Adler, J.B.°, Huber, R.M.°:
Cost-components of lung cancer care within the first three years after initial diagnosis in context of different
treatment regimens. Lung Cancer 90, 274-280 (2015)
Semren, N., Welk, V., Korfei, M., Keller, I.E., Fernandez, I.E., Adler, H., Günther, A., Eickelberg, O.,
Meiners, S.°: Regulation of 26S proteasome activity in pulmonary fibrosis. Am. J. Respir. Crit. Care Med.
192, 1089-1101 (2015)
Semren, N., Habel-Ungewitter, N.C., Fernandez, I.E., Königshoff, M., Eickelberg, O., Stöger, T.,
Meiners, S.°: Validation of the 2nd generation proteasome inhibitor oprozomib for local therapy of pulmonary
fibrosis. PLoS ONE 10:e0136188 (2015)
page 187 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Lung Research
Smith, M., Berdel, D., Nowak, D., Heinrich, J., Schulz, H.°: Sport engagement by accelerometry under field
conditions in German adolescents: Results from GINIPlus. PLoS ONE 10:e0135630 (2015)
Staab-Weijnitz, C.A., Fernandez, I.E., Knüppel, L., Maul, J., Heinzelmann, K., Juan-Guardela, B.M.,
Hennen, E., Preissler, G., Winter, H., Neurohr, C., Hatz, R.A., Lindner, M., Behr, J., Kaminski, N.,
Eickelberg, O.°: FK506-binding protein 10 is a potential novel drug target for idiopathic pulmonary fibrosis.
Am. J. Respir. Crit. Care Med. 192, 455-467 (2015)
Uhl, F., Vierkotten, S., Wagner, D., Burgstaller, G., Costa, R., Koch, I., Lindner, M., Meiners, S.,
Eickelberg, O., Königshoff, M.°: Preclinical validation and imaging of Wnt-induced repair in human 3D lung
tissue cultures. Eur. Respir. J. 46, 1150-1166 (2015)
van Rijt, S.H.°, Bölükbas, D.A., Argyo, C., Datz, S., Lindner, M., Eickelberg, O., Königshoff, M., Bein, T.,
Meiners, S.: Protease-mediated release of chemotherapeutics from mesoporous silica nanoparticles to ex
vivo human and mouse lung tumors. ACS Nano 9, 2377-2389 (2015)
Vogl, M.°, Leidl, R.: Informing management on the future structure of hospital care: An extrapolation of
trends in demand and costs in lung diseases. Eur. J. Health Econ., DOI: 10.1007/s10198-015-0699-4 (2015)
von Berg, A.°, Filipiak-Pittroff, B., Schulz, H., Hoffmann, U., Link, E., Sußmann, M., Schnappinger, M.,
Brüske, I., Standl, M., Krämer, U., Hoffmann, B., Heinrich, J., Bauer, C.P., Koletzko, S., Berdel, D.,
GINIplus Study Group: Allergic manifestation 15 years after early intervention with hydrolyzed formulas - the
GINI study. Allergy 71, 210-219 (2016) [published online 2015]
page 188 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
Aicheler, F., Li, J., Hoene, M., Lehmann, R., Xu, G.°, Kohlbacher, O.°: Retention time prediction improves
identification in nontargeted lipidomics approaches. Anal. Chem. 87, 7698-7704 (2015)
Altevers, J., Lukaschek, K., Baumert, J.J., Kruse, J., Meisinger, C., Emeny, R.T., Ladwig, K.-H.°: Poor
structural social support is associated with an increased risk of Type 2 diabetes mellitus: Findings from the
MONICA/KORA Augsburg cohort study. Diabet. Med. 33, 47-54 (2016) [published online 2015]
#
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Anastasiou, V. , Ninou, E. , Alexopoulou, D., Stertmann, J., Müller, A., Dahl, A., Solimena, M., Speier, S.,
Serafimidis, I.°, Gavalas, A.°: Aldehyde dehydrogenase activity is necessary for beta cell development and
functionality in mice. Diabetologia 59, 139-150 (2015)
Bartel, J.#, Krumsiek, J.#, Schramm, K., Adamski, J., Gieger, C., Herder, C., Carstensen, M., Peters, A.,
Rathmann, W., Roden, M., Strauch, K., Suhre, K., Kastenmüller, G., Prokisch, H., Theis, F.J.°: The
human blood metabolome-transcriptome interface. PLoS Genet. 11:e1005274 (2015)
Bayindir, I., Babaeikelishomi, R., Kocanova, S., Sousa, I.S., Lerch, S., Hardt, O., Wild, S., Bosio, A.,
Bystricky, K., Herzig, S., Vegiopoulos, A.°: Transcriptional pathways in cPGI2-induced adipocyte progenitor
activation for browning. Front. Endocrin. 6:129 (2015)
Beranger, G.E., Djedaini, M., Battaglia, S., Roux, C.H., Scheideler, M., Heymann, D., Amri, E.Z.°, Pisani,
D.F.°: Oxytocin reverses osteoporosis in a sex-dependent manner. Front. Endocrin. 6:81 (2015)
Berti, L., Irmler, M., Zdichavsky, M., Meile, T., Böhm, A., Stefan, N., Fritsche, A., Beckers, J.,
Königsrainer, A., Häring, H.-U., Hrabě de Angelis, M., Staiger, H.°: Fibroblast growth factor 21 is elevated
in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of
human abdominal subcutaneous adipocytes. Mol. Metab. 4, 519-527 (2015)
Beutel, O., Roder, F., Birkholz, O., Rickert, C., Steinhoff, H., Grzybek, M., Coskun, Ü., Piehler, J.:
Two-dimensional trap for ultrasensitive quantification of transient protein interactions. ACS Nano 9,
9783-9791 (2015)
Bongers, M.N.°, Stefan, N., Fritsche, A., Häring, H.-U., Nikolaou, K., Schick, F., Machann, J.:
Lebervolumen, Leberfettanteil und Körpergewicht im Verlauf einer Lebensstilinterventionsstudie : Eine
Analyse mit quantitativen MR-basierten Methoden. Radiologe 55, 323-328 (2015)
Bonifacio, E., Ziegler, A.-G., Klingensmith, G., Schober, E., Bingley, P.J., Rottenkolber, M., Theil, A.,
Eugster, A., Puff, R., Peplow, C., Buettner, F., Lange, K., Hasford, J., Achenbach, P.°: Effects of high-dose
oral insulin on immune responses in children at high risk for type 1 diabetes: The Pre-POINT randomized
clinical trial. JAMA 313, 1541-1549 (2015)
Bonifacio, E.°: Predicting type 1 diabetes using biomarkers. Diabetes Care 38, 989-996 (2015)
Boulet, M.M., Chevrier, G., Grenier-Larouche, T., Pelletier, M.P., Nadeau, M., Scarpa, J., Prehn, C.,
Marette, A., Adamski, J., Tchernof, A.°: Alterations of plasma metabolite profiles related to adipose tissue
distribution and cardiometabolic risk. Am. J. Physiol. Endocrinol. Metab. 309, E736-E746 (2015)
page 189 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
Brina, D.°, Miluzio, A., Ricciardi, S., Clarke, K., Davidsen, P.K., Viero, G., Tebaldi, T., Offenhäuser, N.,
Rozman, J., Rathkolb, B., Neschen, S., Klingenspor, M., Wolf, E., Gailus-Durner, V., Fuchs, H., Hrabě
de Angelis, M., Quattrone, A., Falciani, F., Biffo, S.°: eIF6 coordinates insulin sensitivity and lipid
metabolism by coupling translation to transcription. Nat. Commun. 6:8261 (2015)
Bunz, H., Weyrich, P., Peter, A., Baumann, D., Tschritter, O., Guthoff, M., Beck, R., Jahn, G., Artunc, F.,
Haering, H., Heyne, N., Wagner, R.: Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) and
proteinuria predict severity of acute kidney injury in Puumala virus infection. BMC Infect. Dis. 15, 464 (2015)
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CARDIoGRAMplusC4D Consortium (Nikpay, M. , Goel, A. , Won, H. , Hall, L.M. , Willenborg, C. , Kanoni,
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S. , Saleheen, D. , Gieger, C., Meitinger, T., Peters, A., Watkins, H.°, Kathiresan, S.°, MacPherson, R.°): A
comprehensive 1000 genomes–based genome-wide association meta-analysis of coronary artery disease.
Nat. Genet. 47, 1121-1130 (2015)
Catani, M., Walther, D., Christie, M.R., McLaughlin, K.A., Bonifacio, E., Eugster, A.°: Isolation of human
monoclonal autoantibodies derived from pancreatic lymph node and peripheral blood B cells of islet
autoantibody-positive patients. Diabetologia 59, 294-298 (2016) [published online 2015]
Chambers, J.C.°, Loh, M., Lehne, B., Drong, A., Kriebel, J., Motta, V., Wahl, S., Elliott, H.R., Rota, F., Scott,
W.R., Zhang, W., Tan, S.T., Campanella, G., Chadeau-Hyam, M., Yengo, L., Richmond, R.C.,
Adamowicz-Brice, M., Afzal, U., Bozaoglu, K., Mok, Z.Y., Ng, H.K., Pattou, F., Prokisch, H., Rozario, M.A.,
Tarantini, L., Abbott, J., Ala-Korpela, M., Albetti, B., Ammerpohl, O., Bertazzi, P.A., Blancher, C., Caiazzo,
R., Danesh, J., Gaunt, T.R., de Lusignan, S., Gieger, C., Illig, T., Jha, S., Jones, S., Jowett, J., Kangas, A.J.,
Kasturiratne, A., Kato, N., Kotea, N., Kowlessur, S., Pitkäniemi, J., Punjabi, P., Saleheen, D., Schafmayer,
C., Soininen, P., Tai, E.S., Thorand, B., Tuomilehto, J., Wickremasinghe, A.R., Kyrtopoulos, S.A., Aitman,
T.J., Herder, C., Hampe, J., Cauchi, S., Relton, C.L., Froguel, P., Soong, R., Vineis, P., Jarvelin, M.R., Scott,
J., Grallert, H., Bollati, V., Elliott, P., McCarthy, M.I., Kooner, J.S.: Epigenome-wide association of DNA
methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: A
nested case-control study. Lancet Diabet. Endocrinol. 3, 526-534 (2015)
Cheng, Y.S., Seibert, O., Klöting, N., Dietrich, A., Straßburger, K., Fernández-Veledo, S., Vendrell, J.J.,
Zorzano, A., Blüher, M., Herzig, S., Berriel Diaz, M.°, Teleman, A.A.°: PPP2R5C couples hepatic glucose
and lipid homeostasis. PLoS Genet. 11:e1005561 (2015)
Chmelova, H., Cohrs, C.M., Chouinard, J.A., Petzold, C., Kuhn, M., Chen, C., Roeder, I., Kretschmer, K.,
Speier, S.°: Distinct roles of β-cell mass and function during type 1 diabetes onset and remission. Diabetes
64, 2148-2160 (2015)
Clemmensen, C., Müller, T.D., Finan, B., Tschöp, M.H.°, DiMarchi, R.: Current and emerging treatment
options in diabetes care. Handb. Exp. Pharmacol. 233, 437-459 (2016) [published online 2015]
page 190 of 213
31.12.2015
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joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
Clemmensen, C., Finan, B., Fischer, K., Tom, R.Z., Legutko, B., Sehrer, L., Heine, D., Grassl, N.,
Meyer, C.W., Henderson, B., Hofmann, S.M., Tschöp, M.H., van der Ploeg, L.H.T., Müller, T.D.°: Dual
melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese
mice. EMBO Mol. Med. 7, 288-298 (2015)
Conlon, T.M., Bartel, J., Ballweg, K., Günter, S., Prehn, C., Krumsiek, J., Meiners, S., Theis, F.J.,
Adamski, J., Eickelberg, O., Yildirim, A.Ö.°: Metabolomics screening identifies reduced L-carnitine to be
associated with progressive emphysema. Clin. Sci. 130, 273-287 (2015)
Curado, M.R., Cossio, E.G., Broetz, D., Agostini, M., Cho, W., Brasil, F.L., Yilmaz, O., Liberati, G., Lepski,
G., Birbaumer, N., Ramos-Murguialday, A.: Residual upper arm motor function primes innervation of paretic
forearm muscles in chronic stroke after Brain-Machine Interface (BMI) training. PLoS ONE 10:e0140161
(2015)
Dai, W., Yin, P., Zeng, Z., Kong, H., Tong, H., Xu, Z.L., Lu, X., Lehmann, R.°, Xu, G.W.°: Nontargeted
modification-specific metabolomics study based on liquid chromatography high-resolution mass
spectrometry. Anal. Chem. 86, 9146-9153 (2014)
page 191 of 213
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° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
Day, F.R., Ruth, K.S., Thompson, D.J., Lunetta, K.L., Pervjakova, N., Chasman, D.I., Stolk, L., Finucane,
H.K., Sulem, P., Bulik-Sullivan, B., Esko, T., Johnson, A.D., Elks, C.E., Franceschini, N., He, C., Altmaier,
E.M., Brody, J.A., Franke, L.L., Huffman, J.E., Keller, M.F., McArdle, P.F., Nutile, T., Porcu, E., Robino, A.,
Rose, L.M., Schick, U.M., Smith, J.A., Teumer, A., Traglia, M., Vuckovic, D., Yao, J., Zhao, W., Albrecht, E.,
Amin, N., Corre, T., Hottenga, J.J., Mangino, M., Smith, A.V., Tanaka, T., Abecasis, G.R., Andrulis, I.L.,
Anton-Culver, H., Antoniou, A.C., Arndt, V., Arnold, A.M., Barbieri, C., Beckmann, M.W., Beeghly-Fadiel, A.,
Benítez, J., Bernstein, L., Bielinski, S.J., Blomqvist, C., Boerwinkle, E., Bogdanova, N.V., Bojesen, S.E.,
Bolla, M.K., Borresen-Dale, A.L., Boutin, T.S., Brauch, H., Brenner, H., Brüning, T., Burwinkel, B., Campbell,
A., Campbell, H., Chanock, S.J., Chapman, J.R., Chen, Y.D., Chenevix-Trench, G., Couch, F.J., Coviello,
A.D., Cox, A., Czene, K., Darabi, H., de Vivo, I., Demerath, E.W., Dennis, J., Devilee, P., Dörk, T.,
Dos-Santos-Silva, I., Dunning, A.M., Eicher, J.D., Fasching, P.A., Faul, J.D., Figueroa, J., Flesch-Janys, D.,
Gandin, I., Garcia, M.E., Garcia-Closas, M., Giles, G.G., Girotto, G.G., Goldberg, M.S., González-Neira, A.,
Goodarzi, M.O., Grove, M.L., Gudbjartsson, D.F., Guénel, P., Guo, X., Haiman, C.A., Hall, P., Hamann, U.,
Henderson, B.E., Hocking, L.J., Hofman, A., Homuth, G., Hooning, M.J., Hopper, J.L., Hu, F.B., Huang, J.,
Humphreys, K., Hunter, D.J., Jakubowska, A., Jones, S.E., Kabisch, M., Karasik, D., Knight, J.A., Kolcic, I.,
Kooperberg, C., Kosma, V.M., Kriebel, J., Kristensen, V., Lambrechts, D., Langenberg, C., Li, J., Li, X.,
Lindström, S., Liu, Y., Luan, J., Lubinski, J., Mägi, R., Mannermaa, A., Manz, J., Margolin, S., Marten, J.,
Martin, N.G., Masciullo, C., Meindl, A., Michailidou, K., Mihailov, E., Milani, L., Milne, R.L., Müller-Nurasyid,
M., Nalls, M., Neale, B.M., Nevanlinna, H., Neven, P., Newman, A.B., Nordestgaard, B.G., Olson, J.E.,
Padmanabhan, S., Peterlongo, P., Peters, U., Petersmann, A., Peto, J., Pharoah, P.D., Pirastu, N.N., Pirie,
A., Pistis, G., Polasek, O., Porteous, D.J., Psaty, B.M., Pylkäs, K., Radice, P., Raffel, L.J., Rivadeneira, F.,
Rudan, I., Rudolph, A., Ruggiero, D., Sala, C.F., Sanna, S., Sawyer, E.J., Schlessinger, D., Schmidt, M.K.,
Schmidt, F., Schmutzler, R.K., Schoemaker, M.J., Scott, R.A., Seynaeve, C.M., Simard, J., Sorice, R.,
Southey, M.C., Stöckl, D., Strauch, K., Swerdlow, A., Taylor, K.D., Thorsteinsdottir, U., Toland, A.E.,
Tomlinson, I., Truong, T., Tryggvadottir, L., Turner, S.T., Vozzi, D., Wang, Q., Wellons, M., Willemsen, G.,
Wilson, J.F., Winqvist, R., Wolffenbuttel, B.B., Wright, A.F., Yannoukakos, D., Zemunik, T., Zheng, W.,
Zygmunt, M., Bergmann, S., Boomsma, D.I., Buring, J.E., Ferrucci, L., Montgomery, G.W., Gudnason, V.,
Spector, T.D., van Duijn, C.M., Alizadeh, B.Z., Ciullo, M., Crisponi, L., Easton, D.F., Gasparini, P.P., Gieger,
C., Harris, T.B., Hayward, C., Kardia, S.L., Kraft, P., McKnight, B., Metspalu, A., Morrison, A.C., Reiner, A.P.,
Ridker, P.M., Rotter, J.I., Toniolo, D., Uitterlinden, A.G., Ulivi, S., Völzke, H., Wareham, N.J., Weir, D.R.,
Yerges-Armstrong, L.M., Price, A.L., Stefansson, K., Visser, J.A., Ong, K.K., Chang-Claude, J., Murabito,
J.M., Perry, J.R.°, Murray, A.: Large-scale genomic analyses link reproductive aging to hypothalamic
signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nat. Genet. 47, 1294-1303 (2015)
Dehghany, J.°, Hoboth, P., Ivanova, A., Mziaut, H., Müller, A., Kalaidzidis, Y., Solimena, M.,
Meyer-Hermann, M.: A spatial model of insulin-granule dynamics in pancreatic β-cells. Traffic 16, 797-813
(2015)
page 192 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
#
#
Deng, T. , Zhu, Z.I. , Zhang, S., Postnikov, Y., Huang, D., Horsch, M., Furusawa, T., Beckers, J., Rozman,
J., Klingenspor, M., Amarie, O.V., Graw, J., Rathkolb, B., Wolf, E., Adler, T., Busch, D.H.,
Gailus-Durner, V., Fuchs, H., Hrabě de Angelis, M., van der Velde, A., Tessarollo, L., Ovcherenko, I.,
Landsman, D., Bustin, M.°: Functional compensation among HMGN variants modulates the DNase I
hypersensitive sites at enhancers. Genome Res. 25, 1295-1308 (2015)
Diakopoulos, K.N., Lesina, M., Wörmann, S., Song, L., Aichler, M., Schild, L., Artati, A., Römisch-Margl,
W., Wartmann, T., Fischer, R., Kabiri, Y., Zischka, H., Halangk, W., Demir, I.E., Pilsak, C., Walch, A.K.,
Mantzoros, C.S., Steiner, J.M., Erkan, M., Schmid, R.M., Witt, H., Adamski, J., Algül, H.°: Impaired
autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes.
Gastroenterology 148, 626-638 (2015)
Dimitrov, S.°, Besedovsky, L., Born, J., Lange, T.: Differential acute effects of sleep on spontaneous and
stimulated production of tumor necrosis factor in men. Brain Behav. Immun. 47, 201-210 (2015)
Dinter, J.#, Mühlhaus, J.#, Wienchol, C.L., Yi, C.-X., Nürnberg, D., Morin, S., Grüters, A., Köhrle, J.,
Schöneberg, T., Tschöp, M.H., Krude, H., Kleinau, G., Biebermann, H.°: Inverse agonistic action of
3-iodothyronamine at the human trace amine-associated receptor 5. PLoS ONE 10:e0117774 (2015)
Dopico, X.C., Evangelou, M., Ferreira, R.C., Guo, H., Pekalski, M.L., Smyth, D.J., Cooper, N., Burren, O.S.,
Fulford, A.J., Hennig, B.J., Prentice, A.M., Ziegler, A.-G., Bonifacio, E., Wallace, C., Todd, J.A.°:
Widespread seasonal gene expression reveals annual differences in human immunity and physiology. Nat.
Commun. 6:7000 (2015)
Draisma, H.H.#°, Pool, R.#, Kobl, M., Jansen, R.C., Petersen, A.-K., Vaarhorst, A.A., Yet, I., Haller, T.,
Demirkan, A., Esko, T., Zhu, G., Böhringer, S., Beekman, M., van Klinken, J.B., Römisch-Margl, W., Prehn,
C., Adamski, J., de Craen, A.J., van Leeuwen, E.M., Amin, N., Dharuri, H., Westra, H.J., Franke, L., de
Geus, E.J., Hottenga, J.J., Willemsen, G., Henders, A.K., Montgomery, G.W., Nyholt, D.R., Whitfield, J.B.,
Penninx, B.W., Spector, T.D., Metspalu, A., Slagboom, P.E., van Dijk, K.W., 't Hoen, P.A., Strauch, K.,
Martin, N.G., van Ommen, G.J., Illig, T., Bell, J.T., Mangino, M., Suhre, K., McCarthy, M.I., Gieger, C.,
Isaacs, A., van Duijn, C.M., Boomsma, D.I.: Genome-wide association study identifies novel genetic variants
contributing to variation in blood metabolite levels. Nat. Commun. 6:7208 (2015)
Dyar, K.A., Ciciliot, S., Tagliazucchi, G.M., Pallafacchina, G., Tothova, J., Argentini, C., Agatea, L.,
Abraham, R., Ahdesmäki, M., Forcato, M., Bicciato, S., Schiaffino, S., Blaauw, B.: The calcineurin-NFAT
pathway controls activity-dependent circadian gene expression in slow skeletal muscle. Mol. Metab. 4,
823-833 (2015)
Eckel, N., Mühlenbruch, K., Meidtner, K., Boeing, H., Stefan, N., Schulze, M.B.°: Characterization of
metabolically unhealthy normal-weight individuals: Risk factors and their associations with type 2 diabetes.
Metab.-Clin. Exp. 64, 862-871 (2015)
page 193 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
Ehehalt, F., Sturm, D., Rösler, M., Distler, M., Weitz, J., Kersting, S., Ludwig, B., Schwanebeck, U.,
Saeger, H.-D., Solimena, M.°, Grützmann, R.°: Blood glucose homeostasis in the course of partial
pancreatectomy - evidence for surgically reversible diabetes induced by cholestasis. PLoS ONE
10:e0134140 (2015)
Eugster, A.°, Lindner, A., Catani, M., Heninger, A.K., Dahl, A., Klemroth, S., Kühn, D., Dietz, S., Bickle, M.,
Ziegler, A.-G., Bonifacio, E.: High diversity in the TCR repertoire of GAD65 autoantigen-specific human
CD4+ T cells. J. Immunol. 194, 2531-2538 (2015)
Fasan, A.°, Haferlach, C., Eder, C., Alpermann, T., Quante, A.S., Peters, A., Kern, W., Haferlach, T.,
Schnittger, S.: Evaluation of IDH1G105 polymorphism as prognostic marker in intermediate-risk AML. Ann.
Hematol. 94, 1991-2001 (2015)
Feld, G.B., Wilhem, I., Benedict, C., Rüdel, B., Klameth, C., Born, J., Hallschmid, M.°: Central nervous
insulin
signaling
in
sleep-associated
memory
formation
and
neuroendocrine
regulation.
Neuropsychopharmacology 41, 1540-1550 (2016) [published online 2015]
Ferrari, U., Künzel, H.E.°, Tröndle, K., Rottenkolber, M., Kohn, D., Fugmann, M., Banning, F., Weise, M.,
Sacco, V., Hasbargen, U., Hutter, S., Parhofer, K.G., Kloiber, S., Ising, M., Seissler, J., Lechner, A.: Poor
sleep quality is associated with impaired glucose tolerance in women after gestational diabetes. J. Psychiatr.
Res. 65, 166-171 (2015)
Finan, B.°, Clemmensen, C., Müller, T.D.: Emerging opportunities for the treatment of metabolic diseases:
Glucagon-like peptide-1 based multi-agonists. Mol. Cell. Endocrinol. 418, 42-54 (2015)
#
#
Forcisi, S. , Moritz, F. , Lucio, M., Lehmann, R., Stefan, N., Schmitt-Kopplin, P.°: Solutions for low and
high accuracy mass spectrometric data matching. A data-driven annotation strategy in non-targeted
metabolomics. Anal. Chem. 87, 8917-8924 (2015)
Fuchs, Y.F., Jainta, G.W., Kühn, D., Wilhelm, C., Weigelt, M., Karasinsky, A., Upadhyaya, B., Ziegler, A.-G.,
Bonifacio, E.°: Vagaries of the ELISpot assay: Specific detection of antigen responsive cells requires
purified CD8+ T cells and MHC class I expressing antigen presenting cell lines. Clin. Immunol. 157, 216-225
(2015)
Fugmann, M., Uhl, O., Hellmuth, C., Hetterich, H., Kammer, N.N., Ferrari, U., Parhofer, K.G., Koletzko, B.,
Seissler, J., Lechner, A.°: Differences in the serum nonesterified fatty acid profile of young women
associated with a recent history of gestational diabetes and overweight/obesity. PLoS ONE 10:e0128001
(2015)
Fugmann, M., Breier, M., Rottenkolber, M., Banning, F., Ferrari, U., Sacco, V., Grallert, H., Parhofer,
K.G., Seissler, J., Clavel, T., Lechner, A.°: The stool microbiota of insulin resistant women with recent
gestational diabetes, a high risk group for type 2 diabetes. Sci. Rep. 5:13212 (2015)
page 194 of 213
31.12.2015
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joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
Gancheva, S., Koliaki, C., Bierwagen, A., Nowotny, P., Heni, M., Fritsche, A., Häring, H.-U., Szendrödi, J.,
Roden, M.°: Effects of intranasal insulin on hepatic fat accumulation and energy metabolism in humans.
Diabetes 64, 1966-1975 (2015)
Gaulton, K.J.#°, Ferreira, T.#, Lee, Y.#, Raimondo, A.#, Mägi, R.#, Reschen, M.E.#, Mahajan, A., Locke, A.,
William Rayner, N., Robertson, N., Scott, R.A., Prokopenko, I., Scott, L.J., Green, T., Sparso, T., Thuillier, D.,
Yengo, L., Grallert, H., Wahl, S., Frånberg, M., Strawbridge, R.J., Kestler, H., Chheda, H., Eisele, L.,
Gustafsson, S., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Karssen, L.C., van Leeuwen, E.M., Willems,
S.M., Li, M., Chen, H., Fuchsberger, C., Kwan, P., Ma, C., Linderman, M., Lu, Y., Thomsen, S.K., Rundle,
J.K., Beer, N.L., van de Bunt, M., Chalisey, A., Kang, H.M., Voight, B.F., Abecasis, G.R., Almgren, P.,
Baldassarre, D., Balkau, B., Benediktsson, R., Blüher, M., Boeing, H., Bonnycastle, L.L., Bottinger, E.P.,
Burtt, N.P., Carey, J., Charpentier, G., Chines, P.S., Cornelis, M.C., Couper, D.J., Crenshaw, A.T., van Dam,
R.M., Doney, A.S., Dorkhan, M., Edkins, S., Eriksson, J.G., Esko, T., Eury, E., Fadista, J., Flannick, J.,
Fontanillas, P., Fox, C., Franks, P.W., Gertow, K., Gieger, C., Gigante, B., Gottesman, O., Grant, G.B.,
Grarup, N., Groves, C.J., Hassinen, M., Have, C.T., Herder, C., Holmen, O.L., Hreidarsson, A.B., Humphries,
S.E., Hunter, D.J., Jackson, A.U., Jonsson, A., Jørgensen, M.E., Jørgensen, T., Kao, W.L., Kerrison, N.D.,
Kinnunen, L., Klopp, N., Kong, A., Kovacs, P., Kraft, P., Kravic, J., Langford, C., Leander, K., Liang, L.,
Lichtner, P., Lindgren, C.M., Lindholm, E., Linneberg, A., Liu, C.T., Lobbens, S., Luan, J., Lyssenko, V.,
Männisto, S., McLeod, O., Meyer, J., Mihailov, E., Mirza, G., Mühleisen, T.W., Müller-Nurasyid, M.,
Navarro, C., Nöthen, M.M., Oskolkov, N.N., Owen, K.R., Palli, D., Pechlivanis, S., Peltonen, L., Perry, J.R.,
Platou, C.G., Roden, M., Ruderfer, D., Rybin, D., van der Schouw, Y.T., Sennblad, B., Sigurdsson, G.,
Stancáková, A., Steinbach, G., Storm, P., Strauch, K., Stringham, H.M., Sun, Q., Thorand, B., Tikkanen, E.,
Tönjes, A., Trakalo, J., Tremoli, E., Tuomi, T., Wennauer, R., Wiltshire, S., Wood, A.R., Zeggini, E., Dunham,
I., Birney, E., Pasquali, L., Ferrer, J., Loos, R.J., Dupuis, J., Florez, J.C., Boerwinkle, E., Pankow, J.S., van
Duijn, C.M., Sijbrands, E., Meigs, J.B., Hu, F.B., Thorsteinsdottir, U., Stefansson, K., Lakka, T.A., Rauramaa,
R., Stumvoll, M., Pedersen, N.L., Lind, L., Keinanen-Kiukaanniemi, S.M., Korpi-Hyovalti, E., Saaristo, T.E.,
Saltevo, J., Kuusisto, J., Laakso, M., Metspalu, A., Erbel, R., Jöcke, K.H., Moebus, S., Ripatti, S., Salomaa,
V., Ingelsson, E., Boehm, B.O., Bergman, R.N., Collins, F.S., Mohlke, K.L., Koistinen, H.A., Tuomilehto, J.,
Hveem, K., Njølstad, I., Deloukas, P., Donnelly, P.J., Hattersley, A.T., de Faire, U., Hamsten, A., Illig, T.,
Peters, A., Cauchi, S., Sladek, R., Froguel, P., Hansen, T., Pedersen, O., Morris, A.D., Palmer, C.N.,
Kathiresan, S., Melander, O., Nilsson, P.M., Groop, L.C., Barroso, I., Langenberg, C., Wareham, N.J.,
O'Callaghan, C.A., Gloyn, A.L., Altshuler, D., Boehnke, M., Teslovich, T.M., McCarthy, M.I.°, Morris, A.P.°,
DIAGRAM Consortium: Genetic fine mapping and genomic annotation defines causal mechanisms at type 2
diabetes susceptibility loci. Nat. Genet. 47, 1415-1425 (2015)
Gerst, F., Kaiser, G., Panse, M., Sartorius, T., Pujol, A., Hennige, A.M., Machicao, F., Lammers, R.,
Bosch, F., Häring, H.-U., Ullrich, S.°: Protein kinase Cδ regulates nuclear export of FOXO1 through
phosphorylation of the chaperone 14-3-3ζ. Diabetologia 58, 2819-2831 (2015)
Giannopoulou, E.Z., Winkler, C., Chmiel, R., Matzke, C., Scholz, M., Beyerlein, A., Achenbach, P.,
Bonifacio, E., Ziegler, A.-G.°: Islet autoantibody phenotypes and incidence in children at increased risk for
type 1 diabetes. Diabetologia 58, 2317-2323 (2015)
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HMGU authors are given in bold letters
German Center for Diabetes Research
Grabner, G.F., Eichmann, T.O., Wagner, B., Gao, Y., Farzi, A., Taschler, U., Radner, F.P., Schweiger, M.,
Lass, A., Holzer, P., Zinser, E., Tschöp, M.H., Yi, C.-X., Zimmermann, R.: Deletion of monoglyceride lpase
in astrocytes attenuates lipopolysaccharide-induced neuroinflammation. J. Biol. Chem. 291, 913-923 (2016)
[published online 2015]
Gutierrez, D.A., Muralidhar, S., Feyerabend, T.B., Herzig, S., Rodewald, H.R.°: Hematopoietic Kit deficiency,
rather than lack of mast cells, protects mice from obesity and insulin resistance. Cell Metab. 21, 678-691
(2015)
Halama, A., Horsch, M., Kastenmüller, G., Möller, G., Kumar, P., Prehn, C., Laumen, H., Hauner, H.,
Hrabě de Angelis, M., Beckers, J., Suhre, K., Adamski, J.°: Metabolic switch during adipogenesis: From
branched chain amino acid catabolism to lipid synthesis. Arch. Biochem. Biophys. 589, 93-107 (2015)
Hallschmid, M., Oster, H., Schultes, B., Schmid, S.M.°: Kurzer, gestörter und unregelmäßiger Schlaf: Die
schädlichen Auswirkungen auf den menschlichen Stoffwechsel. Dtsch. Med. Wochenschr. 140, 1278-1283
(2015)
Hansen, J.S., Clemmesen, J.O., Secher, N.H., Hoene, M., Drescher, A., Weigert, C., Pedersen, B.K.,
Plomgaard, P.°: Glucagon-to-insulin ratio is pivotal for splanchnic regulation of FGF-21 in humans. Mol.
Metab. 4, 551-560 (2015)
Hansen, J.S., Zhao, X., Irmler, M., Liu, X., Hoene, M., Scheler, M., Li, Y., Beckers, J., Hrabě de Angelis,
M., Häring, H.-U., Pedersen, B.K., Lehmann, R., Xu, G.°, Plomgaard, P.°, Weigert, C.°: Type 2 diabetes
alters metabolic and transcriptional signatures of glucose and amino acid metabolism during exercise and
recovery. Diabetologia 58, 1845-1854 (2015)
Häring, H.-U., Hrabě de Angelis, M., Joost, H.G., Roden, M., Schürmann, A., Solimena, M.: 5 Jahre
erfolgreiche translationale Forschung - Deutsches Zentrum für Diabetesforschung. Diabetes akt. 13, 58-62
(2015)
Heinze, J.M., Preissl, H.°, Fritsche, A., Frank, S.: Controversies in fat perception. Physiol. Behav. 152,
479-493 (2015)
Heinzmann, S.S.°, Schmitt-Kopplin, P.: Deep metabotyping of the murine gastrointestinal tract for the
visualization of digestion and microbial metabolism. J. Proteome Res. 14, 2267-2277 (2015)
Herder, C.°, Ouwens, D.M., Carstensen, M., Kowall, B., Huth, C., Meisinger, C., Rathmann, W., Roden, M.,
Thorand, B.: Adiponectin may mediate the association between omentin, circulating lipids and insulin
sensitivity: Results from the KORA F4 study. Eur. J. Endocrinol. 172, 423-432 (2015)
Hoboth, P., Müller, A., Ivanova, A., Mziaut, H., Dehghany, J., Sönmez, A., Lachnit, M., Meyer-Hermann,
M., Kalaidzidis, Y., Solimena, M.°: Aged insulin granules display reduced microtubule-dependent mobility
and are disposed within actin-positive multigranular bodies. Proc. Natl. Acad. Sci. U.S.A. 112, E667-E676
(2015)
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German Center for Diabetes Research
Homuth, G.°, Wahl, S., Mueller, C., Schurmann, C., Maeder, U., Blankenberg, S., Carstensen, M., Doerr, M.,
Endlich, K., Englbrecht, C., Felix, S.B., Gieger, C., Grallert, H., Herder, C., Illig, T., Kruppa, J., Marzi, C.S.,
Mayerle, J., Meitinger, T., Metspalu, A., Nauck, M., Peters, A., Rathmann, W., Reinmaa, E., Rettig, R.,
Roden, M., Schillert, A., Schramm, K., Steil, L., Strauch, K., Teumer, A., Voelzke, H., Wallaschofski, H.,
Wild, P.S., Ziegler, A., Voelker, U., Prokisch, H., Zeller, T.: Extensive alterations of the whole-blood
transcriptome are associated with body mass index: Results of an mRNA profiling study involving two large
population-based cohorts. BMC Med. Genomics 8:65 (2015)
Hrabě de Angelis, M.#, Nicholson, G.#, Selloum, M.#, White, J.K.#, Morgan, H.#, Ramirez-Solis, R.#, Sorg,
T.#, Wells, S.#, Fuchs, H.#, Fray, M.#, Adams, D.J., Adams, N.C., Adler, T., Aguilar-Pimentel, J.A.,
Ali-Hadji, D., Amann, G., André, P., Atkins, S., Auburtin, A., Ayadi, A., Becker, J., Becker, L., Bedu, E.,
Bekeredjian, R., Birling, M.C., Blake, A., Bottomley, J., Bowl, M.R., Brault, V., Busch, D.H., Bussell, J.N.,
Calzada-Wack, J., Cater, H., Champy, M.F., Charles, P., Chevalier, C., Chiani, F., Codner, G.F., Combe, R.,
Cox, R.D., Dalloneau, E., Dierich, A., di Fenza, A., Doe, B., Duchon, A., Eickelberg, O., Esapa, C.T., Fertak,
L.E., Feigel, T., Emelyanova, I., Estabel, J., Favor, J., Flenniken, A.M., Gambadoro, A., Garrett, L., Gates,
H., Gerdin, A.K., Gkoutos, G.V., Greenaway, S., Glasl, L., Goetz, P., da Cruz, I.G., Götz, A., Graw, J.,
Guimond, A., Hans, W., Hicks, G., Hölter, S.M., Höfler, H., Hancock, J.M., Hoehndorf, R., Hough, T.,
Houghton, R., Hurt, A., Ivandic, B., Jacobs, H., Jacquot, S., Jones, N., Karp, N.A., Katus, H.A., Kitchen, S.,
Klein-Rodewald, T., Klingenspor, M., Klopstock, T., Lalanne, V., Leblanc, S., Lengger, C., le Marchand,
E., Ludwig, T., Lux, A., McKerlie, C., Maier, H., Mandel, J.L., Marschall, S., Mark, M., Melvin, D.G.,
Meziane, H., Micklich, K., Mittelhauser, C., Monassier, L., Moulaert, D., Müller, S., Naton, B., Neff, F.,
Nolan, P.M., Nutter, L.M., Ollert, M., Pavlovic, G., Pellegata, N.S., Peter, E., Petit-Demoulière, B., Pickard,
A., Podrini, C., Potter, P., Pouilly, L., Puk, O., Richardson, D., Rousseau, S., Quintanilla-Fend, L., Quwailid,
M.M., Rácz, I., Rathkolb, B., Riet, F., Rossant, J., Roux, M., Rozman, J., Ryder, E., Salisbury, J., Santos,
L., Schäble, K.-H., Schiller, E., Schrewe, A., Schulz, H., Steinkamp, R., Simon, M., Stewart, M., Stöger,
C., Stöger, T., Sun, M., Sunter, D., Teboul, L., Tilly, I., Tocchini-Valentini, G.P., Tost, M., Treise, I.,
Vasseur, L., Velot, E., Vogt Weisenhorn, D.M., Wagner, C., Walling, A., Wattenhofer-Donze, M., Weber, B.,
Wendling, O., Westerberg, H., Willershäuser, M., Wolf, E., Wolter, A., Wood, J., Wurst, W., Yildirim, A.Ö.,
Zeh, R., Zimmer, A., Zimprich, A., Holmes, C.#, Steel, K.P.#, Herault, Y.#, Gailus-Durner, V.#, Mallon,
A.M.#, Brown, S.D.#°: Analysis of mammalian gene function through broad-based phenotypic screens across
a consortium of mouse clinics. Nat. Genet. 47, 969-978 (2015)
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Huan, T. , Esko, T. , Peters, M.J. , Pilling, L.C. , Schramm, K. , Schurmann, C. , Chen, B.H., Liu, C.,
Joehanes, R., Johnson, A.D., Yao, C., Ying, S.X., Courchesne, P., Milani, L., Raghavachari, N., Wang, R.,
Liu, P., Reinmaa, E., Dehghan, A., Hofman, A., Uitterlinden, A.G., Hernandez, D.G., Bandinelli, S., Singleton,
A., Melzer, D., Metspalu, A., Carstensen, M., Grallert, H., Herder, C., Meitinger, T., Peters, A., Roden, M.,
Waldenberger, M., Dörr, M., Felix, S.B., Zeller, T., ICBP Consortium (Levy, D.°), Vasan, R.S., O'Donnell,
C.J., Munson, P.J., Yang, X.°, Prokisch, H.°, Völker, U.°, van Meurs, J.B.°, Ferrucci, L.°: A meta-analysis of
gene expression signatures of blood pressure and hypertension. PLoS Genet. 11:e1005035 (2015)
Hudak, S.K., Overkamp, D., Wagner, R., Häring, H.-U., Heni, M.°: Ketoacidosis in a non-diabetic woman
who was fasting during lactation. Nutr. J. 14:117 (2015)
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German Center for Diabetes Research
Huerta-Cepas, J., Szklarczyk, D., Forslund, K., Cook, H., Heller, D., Walter, M.C., Rattei, T., Mende, D.R.,
Sunagawa, S., Kuhn, M., Jensen, L.J., von Mering, C., Bork, P.: eggNOG 4.5: A hierarchical orthology
framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences. Nucleic
Acids Res. 44, D286-D293 (2016) [published online 2015]
Huth, C., Beuerle, S., Zierer, A., Heier, M., Herder, C., Kaiser, T., Koenig, W., Kronenberg, F., Oexle, K.,
Rathmann, W., Roden, M., Schwab, S., Seissler, J., Stöckl, D., Meisinger, C., Peters, A., Thorand, B.°:
Biomarkers of iron metabolism are independently associated with impaired glucose metabolism and type 2
diabetes: The KORA F4 Study. Eur. J. Endocrinol. 173, 643-653 (2015)
Jacobs, S., Jager, S., Jansen, E., Peter, A., Stefan, N., Boeing, H., Schulze, M.B., Kröger, J.°: Associations
of erythrocyte fatty acids in the de novo lipogenesis pathway with proxies of liver fat accumulation in the
EPIC-Potsdam study. PLoS ONE 10:e0127368 (2015)
Kälin, S., Heppner, F.L., Bechmann, I., Prinz, M., Tschöp, M.H.°, Yi, C.-X.: Hypothalamic innate immune
reaction in obesity. Nat. Rev. Endocrinol. 11, 339–351 (2015)
Karbiener, M., Glantschnig, C., Pisani, D.F., Laurencikiene, J., Dahlman, I., Herzig, S., Amri, E.Z.,
Scheideler, M.°: Mesoderm Specific Transcript (MEST) is a negative regulator of human adipocyte
differentiation. Int. J. Obes. 39, 1733-1741 (2015)
Karbiener, M., Scheideler, M.°: Microarray analysis of small non-coding RNAs. Methods Mol. Biol. 1296,
161-171 (2015)
Kastenmüller, G., Raffler, J., Gieger, C., Suhre, K.°: Genetics of human metabolism: An update. Hum.
Mol. Genet. 24, R93-R101 (2015)
Kaszuba, K.#, Grzybek, M.#, Orłowski, A., Danne, R., Róg, T., Simons, K.°, Coskun, Ü.°, Vattulainen, I.°:
N-Glycosylation as determinant of epidermal growth factor receptor conformation in membranes. Proc. Natl.
Acad. Sci. U.S.A. 112, 4334–4339 (2015)
Keipert, S., Kutschke, M., Lamp, D., Brachthäuser, L., Neff, F., Meyer, C.W., Oelkrug, R., Kharitonenkov,
A., Jastroch, M.°: Genetic disruption of uncoupling protein 1 in mice renders brown adipose tissue a
significant source of FGF21 secretion. Mol. Metab. 4, 537-542 (2015)
Kirsten, H., Scholz, M., Kovacs, P., Grallert, H., Peters, A., Strauch, K., Frank, J., Rietschel, M., Nöthen,
M.M., Witt, H., Rosendahl, J.°: Genetic variants of lipase activity in chronic pancreatitis. Gut 65, 184-185
(2016) [published online 2015]
Klüppelholz, B., Thorand, B., Koenig, W., de Las Heras Gala, T., Meisinger, C., Huth, C., Giani, G.,
Franks, P.W., Roden, M., Rathmann, W., Peters, A., Herder, C.°: Association of subclinical inflammation
with deterioration of glycaemia before the diagnosis of type 2 diabetes: The KORA S4/F4 study. Diabetologia
58, 2269-2277 (2015)
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German Center for Diabetes Research
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Kluth, O. , Matzke, D. , Kamitz, A., Jähnert, M., Vogel, H., Scherneck, S., Schulze, M., Staiger, H.,
Machicao, F., Häring, H.-U., Joost, H.G., Schürmann, A.: Identification of four mouse diabetes candidate
genes altering β-cell proliferation. PLoS Genet. 11:e1005506 (2015)
Koch, M., Baurecht, H., Ried, J.S., Rodriguez, E., Schlesinger, S., Volks, N., Gieger, C., Rückert, I.-M.,
Heinrich, L., Willenborg, C., Smith, C., Peters, A., Thorand, B., Koenig, W., Lamina, C., Jansen, H.,
Kronenberg, F., Seissler, J., Thiery, J., Rathmann, W., Schunkert, H., Erdmann, J., Barker, J., Nair, R.P.,
Tsoi, L.C., Elder, J.T., Mrowietz, U., Weichenthal, M., Mucha, S., Schreiber, S., Franke, A., Schmitt, J., Lieb,
W., Weidinger, S.°: Psoriasis and cardiometabolic traits: Modest association but distinct genetic
architectures. J. Invest. Dermatol. 135, 1283-1293 (2015)
Kong, B., Wu, W., Cheng, T., Schlitter, A.M., Qian, C., Bruns, P., Jian, Z., Jager, C., Regel, I., Raulefs, S.,
Behler, N., Irmler, M., Beckers, J., Friess, H., Erkan, M., Siveke, J.T., Tannapfel, A., Hahn, S.A., Theis,
F.J., Esposito, I., Kleeff, J., Michalski, C.W.°: A subset of metastatic pancreatic ductal adenocarcinomas
depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling. Gut 65, 647-657
(2016) [published online 2015]
Kovarova, M., Königsrainer, I., Königsrainer, A., Machicao, F., Häring, H.-U., Schleicher, E.°, Peter, A.:
The genetic variant I148M in PNPLA3 is associated with increased hepatic retinyl-palmitate storage in
humans. J. Clin. Endocrinol. Metab. 100, E1568–E1574 (2015)
Kröger, J.°, Jacobs, S., Jansen, E.H.J.M., Fritsche, A., Boeing, H., Schulze, M.B.: Erythrocyte membrane
fatty acid fluidity and risk of type 2 diabetes in the EPIC-Potsdam study. Diabetologia 58, 282-289 (2015)
Krumsiek, J.#, Mittelstraß, K.#, Do, K.T., Stückler, F., Ried, J.S., Adamski, J., Peters, A., Illig, T.,
Kronenberg, F., Friedrich, N., Nauck, M., Pietzner, M., Mook-Kanamori, D.O., Suhre, K., Gieger, C.,
Grallert, H., Theis, F.J.°, Kastenmüller, G.°: Gender-specific pathway differences in the human serum
metabolome. Metabolomics 11, 1815-1833 (2015)
Kullmann, S.°, Schweizer, F., Veit, R., Fritsche, A., Preissl, H.: Compromised white matter integrity in
obesity. Obes. Rev. 16, 273-281 (2015)
Kullmann, S.°, Heni, M., Fritsche, A., Preissl, H.: Insulin action in the human brain: Evidence from
neuroimaging studies. J. Neuroendocrinol. 27, 419-423 (2015)
Kullmann, S.°, Heni, M., Veit, R., Scheffler, K., Machann, J., Häring, H.-U., Fritsche, A., Preissl, H.:
Selective insulin resistance in homeostatic and cognitive control brain areas in overweight and obese adults.
Diabetes Care 38, 1044-1050 (2015)
Kullmann, S., Callaghan, M.F., Heni, M., Weiskopf, N., Scheffler, K., Häring, H.-U., Fritsche, A., Veit, R.,
Preissl, H.: Specific white matter tissue microstructure changes associated with obesity. Neuroimage 125,
36-44 (2015)
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German Center for Diabetes Research
Kunz, M.°, König, I.R., Schillert, A., Kruppa, J., Ziegler, A., Grallert, H., Müller-Nurasyid, M., Lieb, W.,
Franke, A., Ranki, A., Panelius, J., Koskenmies, S., Hasan, T., Kere, J., Rönn, A.C., Simon, J.C., Schmidt,
E., Wenzel, J., Tüting, T., Landsberg, J., Zeller, T., Blankenberg, S., Gläser, R., Patsinakidis, N., Kuhn, A.,
Ibrahim, S.M.: Genome-wide association study identifies new susceptibility loci for cutaneous lupus
erythematosus. Exp. Dermatol. 24, 510-515 (2015)
Laxy, M., Malecki, K.C., Givens, M.L., Walsh, M.C., Nieto, F.J.°: The association between neighborhood
economic hardship, the retail food environment, fast food intake, and obesity: Findings from the Survey of
the Health of Wisconsin. BMC Public Health 15:237 (2015)
Laxy, M.°, Hunger, M., Stark, R.G., Meisinger, C., Kirchberger, I., Heier, M., von Scheidt, W., Holle, R.:
The burden of diabetes mellitus in patients with coronary heart disease: A methodological approach to
assess quality-adjusted life-years based on individual-level longitudinal survey data. Value Health 18,
969-976 (2015)
Laxy, M.°, Stark, R.G., Meisinger, C., Kirchberger, I., Heier, M., von Scheidt, W., Holle, R.: The
effectiveness of German Disease Management Programs (DMPs) in patients with type 2 diabetes mellitus
and coronary heart disease: Results from an observational longitudinal study. Diabetol. Metab. Syndr. 7:77
(2015)
Lehmann, R., Friedrich, T., Krebiehl, G., Sonntag, D., Häring, H.-U., Fritsche, A., Hennige, A.M.°:
Metabolic profiles during an oral glucose tolerance test in pregnant women with and without gestational
diabetes. Exp. Clin. Endocrinol. Diabet. 123, 433-438 (2015)
Lenoir, M., Grzybek, M., Majkowski, M., Rajesh, S., Kaur, J., Whittaker, S.B., Coskun, Ü., Overduin, M.°:
Structural basis of dynamic membrane recognition by trans-Golgi network specific FAPP proteins. J. Mol.
Biol. 427, 966-981 (2015)
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Lim, H.W. , Uhlenhaut, N.H. °, Rauch, A., Weiner, J., Hübner, S., Hubner, N., Won, K.J., Lazar, M.A.,
Tuckermann, J.P.°, Steger, D.J.°: Genomic redistribution of GR monomers and dimers mediates
transcriptional response to exogenous glucocorticoid in vivo. Genome Res. 25, 836-844 (2015)
Linder, K., Schleger, F., Kiefer-Schmidt, I., Fritsche, L., Kümmel, S., Heni, M., Weiss, M., Häring, H.-U.,
Preissl, H.°, Fritsche, A.: Gestational diabetes impairs human fetal postprandial brain activity. J. Clin.
Endocrinol. Metab. 100, 4029-4036 (2015)
Ludwig, B.: Bioartifizielles Pankreas durch Inselzellverkapselung. Diabetologe 11, 558-567 (2015)
Ludwig, B.°, Ludwig, S.: Transplantable bioartificial pancreas devices: Current status and future prospects.
Langenbecks Arch. Surg. 400, 531-540 (2015)
Luisoni, S., Suomalainen, M., Boucke, K., Tanner, L.B., Wenk, M.R., Guan, X.L., Grzybek, M., Coskun, Ü.,
Greber, U.F.°: Co-option of membrane wounding enables virus penetration into cells. Cell Host Microbe 18,
75-85 (2015)
page 200 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
#
#
Lunetta, K.L. , Day, F.R. , Sulem, P., Ruth, K.S., Tung, J.Y., Hinds, D.A., Esko, T., Elks, C.E., Altmaier,
E.M., He, C., Huffman, J.E., Mihailov, E., Porcu, E., Robino, A., Rose, L.M., Schick, U.M., Stolk, L., Teumer,
A., Thompson, D.J., Traglia, M., Wang, C.A., Yerges-Armstrong, L.M., Antoniou, A.C., Barbieri, C., Coviello,
A.D., Cucca, F., Demerath, E.W., Dunning, A.M., Gandin, I., Grove, M.L., Gudbjartsson, D.F., Hocking, L.J.,
Hofman, A., Huang, J., Jackson, R.D., Karasik, D., Kriebel, J., Lange, E.M., Lange, L.A., Langenberg, C., Li,
X., Luan, J., Mägi, R., Morrison, A.C., Padmanabhan, S., Pirie, A., Polasek, O., Porteous, D.J., Reiner, A.P.,
Rivadeneira, F., Rudan, I., Sala, C.F., Schlessinger, D., Scott, R.A., Stöckl, D., Visser, J.A., Völker, U.,
Vozzi, D., Wilson, J.G., Zygmunt, M., EPIC-Interact Consortium, Generation Scotland Consortium,
Boerwinkle, E., Buring, J.E., Crisponi, L., Easton, D.F., Hayward, C., Hu, F.B., Liu, S., Metspalu, A., Pennell,
C.E., Ridker, P.M., Strauch, K., Streeten, E.A., Toniolo, D., Uitterlinden, A.G., Ulivi, S., Völzke, H.,
Wareham, N.J., Wellons, M., Franceschini, N., Chasman, D.I., Thorsteinsdottir, U., Murray, A., Stefansson,
K., Murabito, J.M., Ong, K.K.°, Perry, J.R.°: Rare coding variants and X-linked loci associated with age at
menarche. Nat. Commun. 6:7756 (2015)
Ma, C., Boehnke, M., Lee, S.°, GoT2D Consortium (Gieger, C., Grallert, H., Hrabě de Angelis, M., Huth,
C., Kriebel, J., Meisinger, C., Meitinger, T., Müller-Nurasyid, M., Peters, A., Ried, J.S., Strauch, K.,
Strom, T.M.): Evaluating the calibration and power of three gene-based association tests of rare variants for
the X chromosome. Genet. Epidemiol. 39, 499-508 (2015)
#
#
#
Mahajan, A. , Sim, X. , Ng, H.J. , Manning, A., Rivas, M.A., Highland, H.M., Locke, A.E., Grarup, N., Im,
H.K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K.J., Teslovich, T.M., Rayner,
N.W., Robertson, N.R., Beer, N.L., Rundle, J.K., Bork-Jensen, J., Ladenvall, C., Blancher, C., Buck, D.,
Buck, G., Burtt, N.P., Gabriel, S., Gjesing, A.P., Groves, C.J., Hollensted, M., Huyghe, J.R., Jackson, A.U.,
Jun, G., Justesen, J.M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K.S., Stringham, H.M.,
Syvanen, A.C., Trakalo, J., Abecasis, G., Bell, G.I., Blangero, J., Cox, N.J., Duggirala, R., Hanis, C.L.,
Seielstad, M., Wilson, J.G., Christensen, C., Brandslund, I., Rauramaa, R., Surdulescu, G.L., Doney, A.S.,
Lannfelt, L., Linneberg, A., Isomaa, B., Tuomi, T., Jørgensen, M.E., Jørgensen, T., Kuusisto, J., Uusitupa,
M., Salomaa, V., Spector, T.D., Morris, A.D., Palmer, C.N., Collins, F.S., Mohlke, K.L., Bergman, R.N.,
Ingelsson, E., Lind, L., Tuomilehto, J., Hansen, T., Watanabe, R.M., Prokopenko, I., Dupuis, J., Karpe, F.,
Groop, L., Laakso, M., Pedersen, O., Florez, J.C., Morris, A.P., Altshuler, D., Meigs, J.B., Boehnke, M.,
McCarthy, M.I., Lindgren, C.M.°, Gloyn, A.L.°, T2D-GENES Consortium, GoT2D Consortium (Hrabě de
Angelis, M., Gieger, C., Grallert, H., Huth, C., Kriebel, J., Meisinger, C., Meitinger, T., Peters, A., Ried,
J.S., Strauch, K., Strom, T.M.), GoT2D Consortium (Müller-Nurasyid, M.): Identification and functional
characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the
G6PC2-ABCB11 locus. PLoS Genet. 11:e1004876 (2015)
Medrikova, D., Sijmonsma, T.P., Sowodniok, K., Richards, D.M., Delacher, M., Sticht, C., Gretz, N.,
Schafmeier, T., Feuerer, M., Herzig, S.°: Brown adipose tissue harbors a distinct sub-population of
regulatory T cells. PLoS ONE 10:e0118534 (2015)
Mook-Kanamori, D.O.°, de Mutsert, R., Rensen, P.C., Prehn, C., Adamski, J., Heijer, M.D., le Cessie, S.,
Suhre, K., Rosendaal, F.R., van Dijk, K.W.: Type 2 diabetes is associated with postprandial amino acid
measures. Arch. Biochem. Biophys. 589, 138-144 (2015)
page 201 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
Müller, T.D., Nogueiras, R.A., Andermann, M.L., Andrews, Z.B., Anker, S.D., Argente, J., Batterham, R.,
Benoit, S.C., Bowers, C.Y., Broglio, F., Casanueva, F.F.F., D'Alessio, D., Depoortere, I., Geliebter, A.A.,
Ghigo, E., Cole, P.A., Cowley, M.A., Cummings, D.E., Dagher, A., Diano, S., Dickson, S.L., Dieguez, C.,
Granata, R., Grill, H.J., Grove, K.L., Habegger, K.M., Heppner, K.M., Heiman, M.L., Holsen, L., Holst, B.,
Inui, A., Jansson, J.O., Kirchner, H., Korbonits, M., Laferrère, B., LeRoux, C.W., López, M.D., Morin, S.,
Nakazato, M., Nass, R., Perez-Tilve, D., Pfluger, P.T., Schwartz, T.W., Seeley, R.J., Sleeman, M.W., Sun,
Y., Sussel, L., Tong, J., Thorner, M.O., van der Lely, A.J., van der Ploeg, L.H.T., Zigman, J.M., Kojima, M.,
Kangawa, K., Smith, R.G., Horvath, T., Tschöp, M.H.°: Ghrelin. Mol. Metab. 4, 437–460 (2015)
Müller, T.D.°: The potential of glucagon-like peptide 1 to reverse high-fat, high-sugar diet-related metabolic
damage. Expert Rev. Endocrinol. Metab. 9, 293-295 (2014)
#
#
Nahon, K.J. , Boon, M.R. °, Bakker, L.E.H., Prehn, C., Adamski, J., Jazet, I.M., van Dijk, K.W., Rensen,
P.C.N., Mook-Kanamori, D.O.: Physiological changes due to mild cooling in healthy lean males of white
Caucasian and South Asian descent: A metabolomics study. Arch. Biochem. Biophys. 589, 152-157 (2015)
Neth, K.°, Lucio, M., Walker, A., Zorn, J., Schmitt-Kopplin, P., Michalke, B.: Changes in brain
metallome/metabolome pattern due to a single i.v. injection of manganese in rats. PLoS ONE 10:e0138270
(2015)
Neth, K.°, Lucio, M., Walker, A., Kanawati, B., Zorn, J., Schmitt-Kopplin, P., Michalke, B.: Diverse
serum manganese species affect brain metabolites depending on exposure conditions. Chem. Res. Toxicol.
28, 1434-1442 (2015)
Nettersheim, A., Hallschmid, M., Born, J., Diekelmann, S.°: The role of sleep in motor sequence
consolidation: Stabilization rather than enhancement. J. Neurosci. 35, 6696-6702 (2015)
Nowotny, B., Zahiragic, L., Bierwagen, A., Kabisch, S., Groener, J.B., Nowotny, P.J., Fleitmann, A.K.,
Herder, C., Pacini, G., Erlund, I., Landberg, R., Häring, H.-U., Pfeiffer, A.F., Nawroth, P.P., Roden, M.°:
Low-energy diets differing in fibre, red meat and coffee intake equally improve insulin sensitivity in type 2
diabetes: A randomised feasibility trial. Diabetologia 58, 255-264 (2015)
Okun, J.G., Conway, S., Schmidt, K.V., Schumacher, J., Wang, X., de Guia, R., Zota, A., Klement, J.,
Seibert, O., Peters, A., Maida, A., Herzig, S., Rose, A.J.°: Molecular regulation of urea cycle function by the
liver glucocorticoid receptor. Mol. Metab. 4, 732-740 (2015)
#
#
Oyanedel, C.N. , Kelemen, E. , Scheller, J., Born, J.°, Rose-John, S.: Peripheral and central blockade of
interleukin-6 trans-signaling differentially affects sleep architecture. Brain Behav. Immun. 50, 178-185 (2015)
Panse, M., Gerst, F., Kaiser, G., Teutsch, C.A., Dölker, R., Wagner, R., Häring, H.-U., Ullrich, S.°:
Activation of Extracellular signal-Regulated protein Kinases 1 and 2 (ERK1/2) by Free Fatty Acid Receptor 1
(FFAR1/GPR40) protects from palmitate-induced beta cell death, but plays no role in insulin secretion. Cell.
Physiol. Biochem. 35, 1537-1545 (2015)
page 202 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
Petzold, A.°, Solimena, M.°, Knoch, K.-P.°: Mechanisms of beta cell dysfunction associated with viral
infection. Curr. Diab. Rep. 15:654 (2015)
Pfeiffer, L., Wahl, S., Pilling, L.C., Reischl, E., Sandling, J.K., Kunze, S., Holdt, L.M., Kretschmer, A.,
Schramm, K., Adamski, J., Klopp, N., Illig, T., Hedman, A.K., Roden, M., Hernandez, D.G., Singleton, A.B.,
Thasler, W.E., Grallert, H., Gieger, C., Herder, C., Teupser, D., Meisinger, C., Spector, T.D., Kronenberg,
F., Prokisch, H., Melzer, D., Peters, A., Deloukas, P., Ferrucci, L., Waldenberger, M.°: DNA methylation of
lipid-related genes affects blood lipid levels. Circ. Cardiovasc. Genet. 8, 334-342 (2015)
Pfluger, P.T., Kabra, D.G., Aichler, M., Schriever, S.C., Pfuhlmann, K., Casquero García, V., Lehti, M.,
Weber, J., Kutschke, M., Rozman, J., Elrod, J.W., Hevener, A.L., Feuchtinger, A., Hrabě de Angelis, M.,
Walch, A.K., Rollmann, S.M., Aronow, B.J., Müller, T.D., Perez-Tilve, D., Jastroch, M., de Luca, M.,
Molkentin, J.D., Tschöp, M.H.°: Calcineurin links mitochondrial elongation with energy metabolism. Cell
Metab. 22, 838-850 (2015)
Pivovarova, O.°, von Loeffelholz, C., Ilkavets, I., Sticht, C., Zhuk, S., Murahovschi, V., Lukowski, S., Döcke,
S., Kriebel, J., de Las Heras Gala, T., Malashicheva, A., Kostareva, A., Lock, J.F., Stockmann, M., Grallert,
H., Gretz, N., Dooley, S., Pfeiffer, A.F., Rudovich, N.N.: Modulation of insulin degrading enzyme activity and
liver cell proliferation. Cell Cycle 14, 2293-2300 (2015)
Podkalicka, J., Biernatowska, A., Majkowski, M., Grzybek, M., Sikorski, A.F.°: MPP1 as a factor regulating
phase separation in giant plasma membrane-derived vesicles. Biophys. J. 108, 2201-2211 (2015)
Reis, W.L., Yi, C.-X., Gao, Y., Tschöp, M.H., Stern, J.E.°: Brain innate immunity regulates hypothalamic
arcuate neuronal activity and feeding behavior. Endocrinology 156, 1303-1315 (2015)
Rimmele, U.°, Besedovsky, L., Lange, T., Born, J.: Emotional memory can be persistently weakened by
suppressing cortisol during retrieval. Neurobiol. Learn. Mem. 119, 102-107 (2015)
Rottenkolber, M.#, Ferrari, U.#, Holland, L., Aertsen, S., Kammer, N.N., Hetterich, H., Fugmann, M.,
Banning, F., Weise, M., Sacco, V., Kohn, D., Freibothe, I., Hutter, S., Hasbargen, U., Lehmann, R.,
Grallert, H., Parhofer, K.G., Seissler, J., Lechner, A.°: The diabetes risk phenotype of young women with
recent gestational diabetes. J. Clin. Endocrinol. Metab. 100, E910-E918 (2015)
Rozman, J., Rathkolb, B., Neschen, S., Fuchs, H., Gailus-Durner, V., Klingenspor, M., Wolf, E., Hrabě de
Angelis, M.°: Glucose tolerance tests for systematic screening of glucose homeostasis in mice. Curr. Protoc.
Mouse Biol. 5, 65-84 (2015)
Sartorius, T.°, Drescher, A., Panse, M., Lastovicka, P., Peter, A., Weigert, C., Kostenis, E., Ullrich, S.,
Häring, H.-U.: Mice lacking Free Fatty Acid Receptor 1 (GPR40/FFAR1) are protected against conjugated
linoleic acid-induced fatty liver but develop inflammation and insulin resistance in the brain. Cell. Physiol.
Biochem. 35, 2272-2284 (2015)
page 203 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
#
#
Sartorius, T. °, Peter, A. , Heni, M., Maetzler, W., Fritsche, A., Häring, H.-U., Hennige, A.M.: The brain
response to peripheral insulin declines with age: A contribution of the blood-brain barrier? PLoS ONE
10:e0126804 (2015)
Schäfer, A., Neschen, S., Kahle, M., Sarioglu, H., Gaisbauer, T., Imhof, A., Adamski, J., Hauck, S.M.°,
Ueffing, M.: The epoxyeicosatrienoic acid pathway enhances hepatic insulin signaling and is repressed in
insulin-resistant mouse liver. Mol. Cell. Proteomics 14, 2764-2774 (2015)
Schäfer, M., Oeing, C.U., Rohm, M., Baysal-Temel, E., Lehmann, L.H., Bauer, R., Volz, H.C., Boutros, M.,
Sohn, D., Sticht, C., Gretz, N., Eichelbaum, K., Werner, T., Hirt, M.N., Eschenhagen, T., Müller-Decker, K.,
Strobel, O., Hackert, T., Krijgsveld, J., Katus, H.A., Berriel Diaz, M., Backs, J.°, Herzig, S.°: Ataxin-10 is part
of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia. Mol. Metab. 5, 67-78
(2016) [published online 2015]
Scheler, M., Hrabě de Angelis, M., Al-Hasani, H., Häring, H.-U., Weigert, C.°, Lehr, S.: Methods for
proteomics-based analysis of the human muscle secretome using an in vitro exercise model. Methods Mol.
Biol. 1295, 55-64 (2015)
#
#
Schmidt, E. , Linz, B. , Diekelmann, S., Besedovsky, L., Lange, T., Born, J.°: Effects of an interleukin-1
receptor antagonist on human sleep, sleep-associated memory consolidation, and blood monocytes. Brain
Behav. Immun. 47, 178-185 (2015)
Schmitz, F., Roscioni, S., Lickert, H.°: Repurposing an osteoporosis drug for β cell regeneration in diabetic
patients. Cell Metab. 22, 58-59 (2015)
Schunk, M.°, Stark, R.G., Reitmeir, P., Meisinger, C., Holle, R.: Towards patient-oriented diabetes care:
Results from two KORA surveys in Southern Germany: J. Diabetes Res. 2015:368570 (2015)
Schwab, S., Zierer, A., Heier, M., Fischer, B., Huth, C., Baumert, J.J., Meisinger, C., Peters, A.,
Thorand, B.°: Intake of vitamin and mineral supplements and longitudinal association with HbA1c levels in
the general non-diabetic population - results from the MONICA/KORA S3/F3 study. PLoS ONE 10:e0139244
(2015)
Sebelefsky, C.°, Karner, D., Voitl, J., Klein, F., Voitl, P., Böck, A.: Internet health seeking behaviour of
parents attending a general paediatric outpatient clinic: A cross-sectional observational study. J. Telemed.
Telecare 21, 400-407 (2015)
Segrè, A.V., Wei, N., DIAGRAM Consortium (Florez, J.C.°, Klopp, N., Illig, T., Müller-Nurasyid, M., Peters,
A.): Pathways targeted by antidiabetes drugs are enriched for multiple genes associated with type 2 diabetes
risk. Diabetes 64, 1470-1483 (2015)
page 204 of 213
31.12.2015
Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
Sekula, P., Goek, O.N., Quaye, L., Barrios, C., Levey, A.S., Römisch-Margl, W., Menni, C., Yet, I., Gieger,
C., Inker, L.A., Adamski, J., Gronwald, W., Illig, T., Dettmer, K., Krumsiek, J., Oefner, P.J., Valdes, A.M.,
Meisinger, C., Coresh, J., Spector, T.D., Mohney, R.P., Suhre, K., Kastenmüller, G.°, Köttgen, A.°: A
metabolome-wide association study of kidney function and disease in the general population. J. Am. Soc.
Nephrol. 27, 1175-1188 (2016) [published online 2015]
Sezgin, E., Gutmann, T., Buhl, T., Dirkx, R., Grzybek, M., Coskun, Ü., Solimena, M., Simons, K., Levental,
I.°, Schwille, P.°: Adaptive lipid packing and bioactivity in membrane domains. PLoS ONE 10:e0123930
(2015)
Shariful Islam, S.M.°, Niessen, L.W., Ferrari, U., Ali, L., Seissler, J., Lechner, A.: Effects of mobile phone
SMS to improve glycemic control among patients with type 2 diabetes in Bangladesh: A prospective,
parallel-group, randomized controlled trial. Diabetes Care 38, e112-e113 (2015)
Shariful Islam, S.M.°, Lechner, A., Ferrari, U., Seissler, J., Holle, R., Niessen, L.W.: Mobile phone use and
willingness to pay for SMS for diabetes in Bangladesh. J. Public Health 38, 163-169 (2016) [published online
2015]
page 205 of 213
31.12.2015
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#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
Shungin, D., Winkler, T.W., Croteau-Chonka, D.C., Ferreira, T., Locke, A.E., Mägi, R., Strawbridge, R.J.,
Pers, T.H., Fischer, K., Justice, A.E., Workalemahu, T., Wu, J.M., Buchkovich, M.L., Heard-Costa, N.L.,
Roman, T.S., Drong, A.W., Song, C., Gustafsson, S., Day, F.R., Esko, T., Fall, T., Kutalik, Z., Luan, J.,
Randall, J.C., Scherag, A., Vedantam, S., Wood, A.R., Chen, J., Fehrmann, R.S.N., Karjalainen, J., Kahali,
B., Liu, C.T., Schmidt, E.M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bragg-Gresham, J.L.,
Buyske, S., Demirkan, A., Ehret, G.B., Feitosa, M.F., Goel, A., Jackson, A.U., Johnson, T., Kleber, M.E.,
Kristiansson, K., Mangino, M., Mateo Leach, I., Medina-Gomez, C., Palmer, C.D., Pasko, D., Pechlivanis, S.,
Peters, M.J., Prokopenko, I., Stancáková, A., Ju Sung, Y., Tanaka, T., Teumer, A., van Vliet-Ostaptchouk,
J.V., Yengo, L., Zhang, W., Albrecht, E., Ärnlöv, J., Arscott, G.M., Bandinelli, S., Barrett, A., Bellis, C.,
Bennett, A.J., Berne, C., Blüher, M., Böhringer, S., Bonnet, F., Böttcher, Y., Bruinenberg, M., Carba, D.B.,
Caspersen, I.H., Clarke, R., Daw, E.W., Deelen, J., Deelman, E., Delgado, G., Doney, A.S., Eklund, N.,
Erdos, M.R., Estrada, K., Eury, E., Friedrich, N., Garcia, M.E., Giedraitis, V., Gigante, B., Go, A.S., Golay, A.,
Grallert, H., Grammer, T.B., Gräßler, J., Grewal, J., Groves, C.J., Haller, T., Hallmans, G., Hartman, C.A.,
Hassinen, M., Hayward, C., Heikkilä, K., Herzig, K.H., Helmer, Q., Hillege, H.L., Holmen, O.L., Hunt, S.C.,
Isaacs, A., Ittermann, T., James, A.L., Johansson, I., Juliusdottir, T., Kalafati, I.P., Kinnunen, L., Koenig, W.,
Kooner, I.K., Kratzer, W., Lamina, C., Leander, K., Lee, N.R., Lichtner, P., Lind, L., Lindstrom, J., Lobbens,
S., Lorentzon, M., Mach, F., Magnusson, P.K., Mahajan, A., McArdle, W.L., Menni, C., Merger, S., Mihailov,
E., Milani, L., Mills, R., Moayyeri, A., Monda, K.L., Mooijaart, S.P., Mühleisen, T.W., Mulas, A., Müller, G.,
Müller-Nurasyid, M., Nagaraja, R., Nalls, M.A., Narisu, N., Glorioso, N., Nolte, I.M., Olden, M., Rayner,
N.W., Renström, F., Ried, J.S., Robertson, N.R., Rose, L.M., Sanna, S., Scharnagl, H., Scholtens, S.,
Sennblad, B., Seufferlein, T., Sitlani, C.M., Smith, A.V., Stirrups, K., Stringham, H.M., Sundström, J., Swertz,
M.A., Swift, A.J., Syvanen, A.C., Tayo, B.O., Thorand, B., Thorleifsson, G., Tomaschitz, A., Troffa, C., van
Oort, F.V., Verweij, N., Vonk, J.M., Waite, L.L., Wennauer, R., Wilsgaard, T., Wojczynski, M.K., Wong, A.,
Zhang, Q., Hua Zhao, J., Brennan, E.P., Choi, M., Eriksson, P., Folkersen, L., Franco-Cereceda, A., Gharavi,
A.G., Hedman, A.K., Hivert, M.F., Huang, J., Kanoni, S., Karpe, F., Keildson, S., Kiryluk, K., Liang, L., Lifton,
R.P., Ma, B., McKnight, A.J., McPherson, R., Metspalu, A., Min, J.L., Moffatt, M.F., Montgomery, G.W.,
Murabito, J.M., Nicholson, G., Nyholt, D.R., Olsson, C., Perry, J.R., Reinmaa, E., Salem, R.M., Sandholm,
N., Schadt, E.E., Scott, R.A., Stolk, L., Vallejo, E.E., Westra, H.J., Zondervan, K.T., Amouyel, P., Arveiler, D.,
Bakker, S.J., Beilby, J., Bergman, R.N., Blangero, J., Brown, M.J., Burnier, M., Campbell, H., Chakravarti, A.,
Chines, P.S., Claudi-Boehm, S., Collins, F.S., Crawford, D.C., Danesh, J., de Faire, U., de Geus, E.J., Dörr,
M., Erbel, R., Eriksson, J.G., Farrall, M., Ferrannini, E., Ferrieres, J., Forouhi, N.G., Forrester, T., Franco,
O.H., Gansevoort, R.T., Gieger, C., Gudnason, V., Haiman, C.A., Harris, T.B., Hattersley, A.T., Heliövaara,
M., Hicks, A.A., Hingorani, A.D., Hoffmann, W., Hofman, A., Homuth, G., Humphries, S.E., Hyppönen, E.,
Illig, T., Jarvelin, M.R., Johansen, B., Jousilahti, P., Jula, A.M., Kaprio, J., Kee, F., Keinanen-Kiukaanniemi,
S.M., Kooner, J.S., Kooperberg, C., Kovacs, P., Kraja, A.T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Lakka,
T.A., Langenberg, C., Le Marchand, L., Lehtimäki, T., Lyssenko, V., Männisto, S., Marette, A., Matise, T.C.,
McKenzie, C.A., McKnight, B., Musk, A.W., Möhlenkamp, S., Morris, A.D., Nelis, M., Ohlsson, C., Oldehinkel,
A.J., Ong, K.K., Palmer, L.J., Penninx, B.W., Peters, A., Pramstaller, P.P., Raitakari, O.T., Rankinen, T.,
Rao, D.C., Rice, T.K., Ridker, P.M., Ritchie, M.D., Rudan, I., Salomaa, V., Samani, N.J., Saramies, J.,
Sarzynski, M.A., Schwarz, P.E., Shuldiner, A.R., Staessen, J.A., Steinthorsdottir, V., Stolk, R.P., Strauch,
K., Tönjes, A., Tremblay, A., Tremoli, E., Vohl, M.C., Völker, U., Vollenweider, P., Wilson, J.F., Witteman,
J.C., Adair, L.S., Bochud, M., Boehm, B.O., Bornstein, S.R., Bouchard, C., Cauchi, S., Caulfield, M.J.,
page 206 of 213
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° corresponding authors
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Chambers, J.C., Chasman, D.I., Cooper, R.S., Dedoussis, G., Ferrucci, L., Froguel, P., Grabe, H.J.,
Hamsten, A., Hui, J., Hveem, K., Jockel, K.H., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Marz, W., Munroe,
P.B., Njølstad, I., Oostra, B.A., Palmer, C.N., Pedersen, N.L., Perola, M., Perusse, L., Peters, U., Power, C.,
Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo, T.E., Saleheen, D., Sinisalo, J., Slagboom, P.E.,
Snieder, H., Spector, T.D., Thorsteinsdottir, U., Stumvoll, M., Tuomilehto, J., Uitterlinden, A.G., Uusitupa, M.,
van der Harst, P., Veronesi, G., Walker, M., Wareham, N.J., Watkins, H., Wichmann, H.-E., Abecasis, G.R.,
Assimes, T.L., Berndt, S.I., Boehnke, M., Borecki, I.B., Deloukas, P., Franke, L., Frayling, T.M., Groop, L.C.,
Hunter, D.J., Kaplan, R.C., O'Connell, J.R., Qi, L., Schlessinger, D., Strachan, D.P., Stefansson, K., van
Duijn, C.M., Willer, C.J., Visscher, P.M., Yang, J., Hirschhorn, J.N., Zillikens, M.C., McCarthy, M.I., Speliotes,
E.K., North, K.E., Fox, C.S., Barroso, I., Franks, P.W., Ingelsson, E., Heid, I.M., Loos, R.J., Cupples, L.A.,
Morris, A.P., Lindgren, C.M.°, Mohlke, K.L.°: New genetic loci link adipose and insulin biology to body fat
distribution. Nature 518, 187-196 (2015)
Spetter, M.S., Hallschmid, M.°: Intranasal neuropeptide administration to target the human brain in health
and disease. Mol. Pharm. 12, 2767-2780 (2015)
Stangl, S., Kollerits, B., Lamina, C., Meisinger, C., Huth, C., Stöckl, A., Dähnhardt, D., Böger, C.A., Krämer,
B.K., Peters, A., Kronenberg, F.: Association between apolipoprotein A-IV concentrations and chronic kidney
disease in two large population-based cohorts: Results from the KORA studies. J. Intern. Med. 278, 410-423
(2015)
Stefan, N.°, Staiger, H., Wagner, R., Machann, J., Schick, F., Häring, H.-U., Fritsche, A.: A high-risk
phenotype associates with reduced improvement in glycaemia during a lifestyle intervention in prediabetes.
Diabetologia 58, 2877-2884 (2015)
Stefan, N.°, Artunc, F., Heyne, N., Machann, J., Schleicher, E.D., Häring, H.-U.: Obesity and renal disease:
Not all fat is created equal and not all obesity is harmful to the kidneys. Nephrol. Dial. Transplant., DOI:
10.1093/ndt/gfu081 (2014)
Stemmer, K., Zani, F., Habegger, K.M., Neff, C., Kotzbeck, P., Bauer, M., Yalamanchilli, S., Azad, A.,
Lehti, M., Martins, P.J., Müller, T.D., Pfluger, P.T., Seeley, R.J.°: FGF21 is not required for glucose
homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice. Diabetologia 58,
2414-2423 (2015)
Stoy, C., Sundaram, A., Rios Garcia, M., Wang, X., Seibert, O., Zota, A., Wendler, S., Männle, D., Hinz, U.,
Sticht, C., Muciek, M., Gretz, N., Rose, A.J., Greiner, V., Hofmann, T.G., Bauer, A., Hoheisel, J., Berriel
Diaz, M., Gaida, M.M., Werner, J., Schafmeier, T., Strobel, O.°, Herzig, S.°: Transcriptional co-factor
Transducin Beta-Like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy. EMBO Mol. Med. 7,
1048-1062 (2015)
page 207 of 213
31.12.2015
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#
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° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
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Swerdlow, D.I. , Preiss, D. , Kuchenbaecker, K.B., Holmes, M.V., Engmann, J.E.L., Shah, T., Sofat, R.,
Stender, S., Johnson, P.C.D., Scott, R.A., Leusink, M., Verweij, N., Sharp, S.J., Guo, Y., Giambartolomei, C.,
Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J., Howard, P., Cooper, J.A., Drenos, F., Li, Y.R., Lowe,
G., Gallacher, J., Stewart, M.C.W., Tzoulaki, I., Buxbaum, S.G., Daphne, L.v.d.A., Forouhi, N.G.,
Onland-Moret, N.C., van der Schouw, Y.T., Schnabel, R.B., Hubácek, J.A., Kubínová, R., Baceviciene, M.,
Tamosiunas, A., Pajak, A., Topor-Madry, R., Stepaniak, U., Malyutina, S.A., Baldassarre, D., Sennblad, B.,
Tremoli, E., de Faire, U., Veglia, F., Ford, I., Jukema, J.W., Westendorp, R.G.J., de Borst, G.J., De Jong,
P.A., Algra, A., Spiering, W., Maitland-van der Zee, A.H., Klungel, O.H., de Boer, A., Doevendans, P.A.,
Eaton, C.B., Robinson, J.G., Duggan, D., Kjekshus, J., Downs, J.R., Gotto, A.M., Keech, A.C., Marchioli, R.,
Tognoni, G., Sever, P.S., Poulter, N.R., Waters, D.D., Pedersen, T.R., Amarenco, P., Nakamura, H.,
McMurray, J.J.V., Lewsey, J.D., Chasman, D.I., Ridker, P.M., Maggioni, A.P., Tavazzi, L., Ray, K.K.,
Seshasai, S.R.K., Manson, J.E., Price, J.F., Whincup, P.H., Morris, R.W., Lawlor, D.A., Smith, G.D.,
Ben-Shlomo, Y., Schreiner, P.J., Fornage, M., Siscovick, D.S., Cushman, M., Kumari, M., Wareham, N.J.,
Verschuren, W.M.M., Redline, S., Patel, S.R., Whittaker, J.C., Hamsten, A., Delaney, J.A., Dale, C.E.,
Gaunt, T.R., Wong, A., Kuh, D., Hardy, R., Kathiresan, S., Castillo, B.A., van der Harst, P., Brunner, E.J.,
Tybjaerg-Hansen, A., Marmot, M.G., Krauss, R.M., Tsai, M., Coresh, J., Hoogeveen, R.C., Psaty, B.M.,
Lange, L.A., Hakonarson, H., Dudbridge, F., Humphries, S.E., Talmud, P.J., Kivimaeki, M., Timpson, N.J.,
Langenberg, C., Asselbergs, F.W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J.G., Reiner, A.P., Keating,
B.J., Hingorani, A.D.°, Sattar, N.°, DIAGRAM Consortium (Grallert, H., Gieger, C., Klopp, N., Illig, T.,
Müller-Nurasyid, M., Peters, A.), MAGIC Consortium (Meisinger, C., Thorand, B., Wichmann, H.-E.),
InterAct Consortium: HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence
from genetic analysis and randomised trials. Lancet 385, 351-361 (2015)
Teperino, R., Pospisilik, J.A.°: Determination and analysis of cellular metabolic changes by noncanonical
Hedgehog signaling. Methods Mol. Biol. 1322, 187-198 (2015)
Thiele, I.°, Linseisen, J., Meisinger, C., Schwab, S., Huth, C., Peters, A., Perz, S., Meitinger, T.,
Kronenberg, F., Lamina, C., Thiery, J., Koenig, W., Rathmann, W., Kääb, S., Then, C., Seissler, J.,
Thorand, B.: Associations between calcium and vitamin D supplement use as well as their serum
concentrations and subclinical cardiovascular disease phenotypes. Atherosclerosis 241, 743-751 (2015)
Tokarz, J., Möller, G., Hrabě de Angelis, M., Adamski, J.°: Steroids in teleost fishes: A functional point of
view. Steroids 103, 123-144 (2015)
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Tönjes, A. , Scholz, M. , Breitfeld, J., Marzi, C., Grallert, H., Gross, A., Ladenvall, C., Schleinitz, D., Krause,
K.P., Kirsten, H., Laurila, E., Kriebel, J., Thorand, B., Rathmann, W., Groop, L.C., Prokopenko, I., Isomaa,
B., Beutner, F., Kratzsch, J.K., Thiery, J.J., Faßhauer, M., Klöting, N., Gieger, C., Blüher, M., Stumvoll,
M.W.°, Kovacs, P.°: Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the
regulation of circulating serum chemerin. PLoS Genet. 10:e1004854 (2015)
Tsepilov, Y.A., Shin, S.Y., Soranzo, N., Spector, T.D., Prehn, C., Adamski, J., Kastenmüller, G.,
Wang-Sattler, R., Strauch, K., Gieger, C., Aulchenko, Y.S., Ried, J.S.°: Non-additive effects of genes in
human metabolomics. Genetics 200, 707-718 (2015)
page 208 of 213
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° corresponding authors
HMGU authors are given in bold letters
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Tsuprykov, O., Chaykovska, L., Kretschmer, D., Stasch, J.-P., Pfab, T., Krause-Relle, K., Reichetzeder. C.,
Kalk, P., Adamski, J., Hocher, B.°: Endothelin-1 overexpression improves renal function in eNOS knockout
mice. Cell. Physiol. Biochem. 37, 1474-1490 (2015)
Um, S.H., Sticker-Jantscheff, M., Chau, G.C., Vintersten, K., Mueller, M., Gangloff, Y.G., Adams, R.H.,
Spetz, J.F., Elghazi, L., Pfluger, P.T., Pende, M., Bernal-Mizrachi, E., Tauler, A., Tschöp, M.H., Thomas,
G., Kozma, S.C.°: S6K1 controls pancreatic β cell size independently of intrauterine growth restriction. J.
Clin. Invest. 125, 2736-2747 (2015)
van den Berg, R., Mook-Kanamori, D.O., Donga, E., van Dijk, M., van Dijk, J.G., Lammers, G.J., van
Kralingen, K.W., Prehn, C., Adamski, J., Romijn, J.A., Willems van Dijk, K., Corssmit, E.P.M., Rensen, P.C.,
Biermasz, N.R.°: A single night of sleep curtailment increases plasma acylcarnitines: Novel insights in the
relationship between sleep and insulin resistance. Arch. Biochem. Biophys. 589, 145-151 (2015)
Vettorazzi, S., Bode, C., Dejager, L., Frappart, L., Shelest, E., Klaßen, C., Tasdogan, A., Reichardt, H.M.,
Libert, C., Schneider, M., Weih, F., Uhlenhaut, N.H., David, J.P., Gräler, M.H., Kleiman, A.°, Tuckermann,
J.P.°: Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of
SphK1. Nat. Commun. 6:7796 (2015)
Vogt, S., Zierer, A., Laxy, M., Koenig, W., Linkohr, B., Linseisen, J., Peters, A., Thorand, B.°:
Association of serum vitamin D with change in weight and total body fat in a German cohort of older adults.
Eur. J. Clin. Nutr. 70, 136-139 (2016) [published online 2015]
Wahl, S.#°, Vogt, S.#, Stückler, F., Krumsiek, J., Bartel, J., Kacprowski, T., Schramm, K., Carstensen, M.,
Rathmann, W., Roden, M., Jourdan, C., Kangas, A.J., Soininen, P., Ala-Korpela, M., Nöthlings, U., Boeing,
H., Theis, F.J., Meisinger, C., Waldenberger, M., Suhre, K., Homuth, G., Gieger, C., Kastenmüller, G.,
Illig, T., Linseisen, J., Peters, A., Prokisch, H., Herder, C., Thorand, B.°, Grallert, H.°: Multi-omic
signature of body weight change: Results from a population-based cohort study. BMC Med. 13:48 (2015)
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Walter, M.C. , Öhrman, C. , Myrtennäs, K., Sjödin, A., Byström, M., Larsson, P., Macellaro, A., Forsman,
#
#
M. , Frangoulidis, D. °: Genome sequence of Coxiella burnetii strain Namibia. Stand. Genomic Sci. 9:22
(2014)
Warth, S.C., Höfig, K.P., Hiekel, A., Schallenberg, S., Jovanovic, K., Klein, L., Kretschmer, K., Ansel, K.M.,
Heissmeyer, V.°: Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote
regulatory T-cell differentiation. EMBO J. 34, 1195-1213 (2015)
Weber, S., Salabei, J.K., Möller, G., Kremmer, E., Bhatnagar, A., Adamski, J.°, Barski, O.A.°: Aldo-Keto
Reductase 1B15 (AKR1B15): A mitochondrial human aldo-keto reductase with activity toward steroids and
3-keto-acyl-CoA conjugates. J. Biol. Chem. 290, 6531-6545 (2015)
page 209 of 213
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Westra, H.J. , Arends, D. , Esko, T., Peters, M.J., Schurmann, C., Schramm, K., Kettunen, J., Yaghootkar,
H., Fairfax, B.P., Andiappan, A.K., Li, Y., Fu, J., Karjalainen, J., Platteel, M., Visschedijk, M., Weersma, R.K.,
Kasela, S., Milani, L., Tserel, L., Peterson, P., Reinmaa, E., Hofman, A., Uitterlinden, A.G., Rivadeneira, F.,
Homuth, G., Petersmann, A., Lorbeer, R., Prokisch, H., Meitinger, T., Herder, C., Roden, M., Grallert, H.,
Ripatti, S., Perola, M., Wood, A.R., Melzer, D., Ferrucci, L., Singleton, A.B., Hernandez, D.G., Knight, J.C.,
Melchiotti, R., Lee, B., Poidinger, M., Zolezzi, F., Larbi, A., Wang, Y., van den Berg, L.H., Veldink, J.H.,
Rotzschke, O., Makino, S., Salomaa, V., Strauch, K., Völker, U., van Meurs, J.B., Metspalu, A., Wijmenga,
C., Jansen, R.C., Franke, L.°: Cell specific eQTL analysis without sorting cells. PLoS Genet. 11:e1005223
(2015)
Wiedemann, T., Bielohuby, M., Müller, T.D., Bidlingmaier, M., Pellegata, N.S.°: Obesity in MENX rats is
accompanied by high circulating levels of ghrelin and improved insulin sensitivity. Diabetes 65, 406-420
(2015)
#
#
Willmann, S. , Müller, N.S. , Engert, S., Sterr, M., Burtscher, I., Raducanu, A., Irmler, M., Beckers, J.,
Sass, S., Theis, F.J., Lickert, H.°: The global gene expression profile of the secondary transition during
pancreatic development. Mech. Dev. 139, 51-64 (2016) [published online 2015]
page 210 of 213
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HMGU authors are given in bold letters
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Winkler, T.W. , Justice, A.E. , Graff, M. , Barata, L. , Feitosa, M.F., Chu, S., Czajkowski, J., Esko, T., Fall, T.,
Kilpeläinen, T.O., Lu, Y., Mägi, R., Mihailov, E., Pers, T.H., Rüeger, S., Teumer, A., Ehret, G.B., Ferreira, T.,
Heard-Costa, N.L., Karjalainen, J., Lagou, V., Mahajan, A., Neinast, M.D., Prokopenko, I., Simino, J.,
Teslovich, T.M., Jansen, R., Westra, H.J., White, C.C., Absher, D., Ahluwalia, T.S., Ahmad, S., Albrecht, E.,
Alves, A.C., Bragg-Gresham, J.L., de Craen, A.J., Bis, J.C., Bonnefond, A., Boucher, G., Cadby, G., Cheng,
Y.C., Chiang, C.W., Delgado, G., Demirkan, A., Dueker, N., Eklund, N., Eiriksdottir, G., Eriksson, J.,
Feenstra, B., Fischer, K., Frau, F., Galesloot, T.E., Geller, F., Goel, A., Gorski, M., Grammer, T.B.,
Gustafsson, S., Haitjema, S., Hottenga, J.J., Huffman, J.E., Jackson, A.U., Jacobs, K.B., Johansson, A.,
Kaakinen, M., Kleber, M.E., Lahti, J., Mateo Leach, I., Lehne, B., Liu, Y., Lo, K.S., Lorentzon, M., Luan, J.,
Madden, P.A., Mangino, M., McKnight, B., Medina-Gomez, C., Monda, K.L., Montasser, M.E., Müller, G.,
Müller-Nurasyid, M., Nolte, I.M., Panoutsopoulou, K., Pascoe, L., Paternoster, L., Rayner, N.W., Renström,
F., Rizzi, F., Rose, L.M., Ryan, K.A., Salo, P., Sanna, S., Scharnagl, H., Shi, J., Smith, A.V., Southam, L.,
Stancáková, A., Steinthorsdottir, V., Strawbridge, R.J., Sung, Y.J., Tachmazidou, I., Tanaka, T., Thorleifsson,
G., Trompet, S., Pervjakova, N., Tyrer, J.P., Vandenput, L., van der Laan, S.W., van der Velde, N., van
Setten, J., van Vliet-Ostaptchouk, J.V., Verweij, N., Vlachopoulou, E., Waite, L.L., Wang, S.R., Wang, Z.,
Wild, S.H., Willenborg, C., Wilson, J.F., Wong, A., Yang, J., Yengo, L., Yerges-Armstrong, L.M., Yu, L.,
Zhang, W., Zhao, J.H., Andersson, E.A., Bakker, S.J., Baldassarre, D., Banasik, K., Barcella, M., Barlassina,
C., Bellis, C., Benaglio, P., Blangero, J., Blüher, M., Bonnet, F., Bonnycastle, L.L., Boyd, H.A., Bruinenberg,
M., Buchman, A.S., Campbell, H., Chen, Y.D., Chines, P.S., Claudi-Boehm, S., Cole, J., Collins, F.S., de
Geus, E.J., de Groot, L.C., Dimitriou, M., Duan, J., Enroth, S., Eury, E., Farmaki, A.E., Forouhi, N.G.,
Friedrich, N., Gejman, P.V., Gigante, B., Glorioso, N., Go, A.S., Gottesman, O., Gräßler, J., Grallert, H.,
Grarup, N., Gu, Y.M., Broer, L., Ham, A.C., Hansen, T., Harris, T.B., Hartman, C.A., Hassinen, M., Hastie,
N., Hattersley, A.T., Heath, A.C., Henders, A.K., Hernandez, D., Hillege, H., Holmen, O.L., Hovingh, K.G.,
Hui, J., Husemoen, L.L., Hutri-Kähönen, N., Hysi, P.G., Illig, T., de Jager, P.L., Jalilzadeh, S., Jørgensen, T.,
Jukema, J.W., Juonala, M., Kanoni, S., Karaleftheri, M., Khaw, K.T., Kinnunen, L., Kittner, S.J., Koenig, W.,
Kolcic, I., Kovacs, P., Krarup, N.T., Kratzer, W., Krüger, J., Kuh, D., Kumari, M., Kyriakou, T., Langenberg,
C., Lannfelt, L., Lanzani, C., Lotay, V., Launer, L.J., Leander, K., Lindstrom, J., Linneberg, A., Liu, Y.P.,
Lobbens, S., Luben, R., Lyssenko, V., Männisto, S., Magnusson, P.K., McArdle, W.L., Menni, C., Merger, S.,
Milani, L., Montgomery, G.W., Morris, A.P., Narisu, N., Nelis, M., Ong, K.K., Palotie, A., Perusse, L., Pichler,
I., Pilia, M.G., Pouta, A., Rheinberger, M., Ribel-Madsen, R., Richards, M., Rice, K.M., Rice, T.K., Rivolta, C.,
Salomaa, V., Sanders, A.R., Sarzynski, M.A., Scholtens, S., Scott, R.A., Scott, W.R., Sebert, S., Sengupta,
S., Sennblad, B., Seufferlein, T., Silveira, A., Slagboom, P.E., Smit, J.H., Sparsø, T.H., Stirrups, K., Stolk,
R.P., Stringham, H.M., Swertz, M.A., Swift, A.J., Syvanen, A.C., Tan, S.T., Thorand, B., Tönjes, A.,
Tremblay, A., Tsafantakis, E., van der Most, P.J., Völker, U., Vohl, M.C., Vonk, J.M., Waldenberger, M.,
Walker, R.W., Wennauer, R., Widen, E., Willemsen, G., Wilsgaard, T., Wright, A.F., Zillikens, M.C., van Dijk,
S.C., van Schoor, N.M., Asselbergs, F.W., de Bakker, P.I., Beckmann, J.S., Beilby, J., Bennett, D.A.,
Bergman, R.N., Bergmann, S., Böger, C.A., Boehm, B.O., Boerwinkle, E., Boomsma, D.I., Bornstein, S.R.,
Bottinger, E.P., Bouchard, C., Chambers, J.C., Chanock, S.J., Chasman, D.I., Cucca, F., Cusi, D.,
Dedoussis, G., Erdmann, J., Eriksson, J.G., Evans, D.A., de Faire, U., Farrall, M., Ferrucci, L., Ford, I.,
Franke, L., Franks, P.W., Froguel, P., Gansevoort, R.T., Gieger, C., Grönberg, H., Gudnason, V.,
Gyllensten, U., Hall, P., Hamsten, A., van der Harst, P., Hayward, C., Heliövaara, M., Hengstenberg, C.,
Hicks, A.A., Hingorani, A., Hofman, A., Hu, F., Huikuri, H.V., Hveem, K., James, A.L., Jordan, J.M., Jula, A.,
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Kähönen, M., Kajantie, E., Kathiresan, S., Kiemeney, L.A., Kivimaki, M., Knekt, P.B., Koistinen, H.A.,
Kooner, J.S., Koskinen, S., Kuusisto, J., Maerz, W., Martin, N.G., Laakso, M., Lakka, T.A., Lehtimäki, T.,
Lettre, G., Levinson, D.F., Lind, L., Lokki, M.L., Mäntyselkä, P., Melbye, M., Metspalu, A., Mitchell, B.D., Moll,
F.L., Murray, J.C., Musk, A.W., Nieminen, M.S., Njølstad, I., Ohlsson, C., Oldehinkel, A.J., Oostra, B.A.,
Palmer, L.J., Pankow, J.S., Pasterkamp, G., Pedersen, N.L., Pedersen, O., Penninx, B.W., Perola, M.,
Peters, A., Polasek, O., Pramstaller, P.P., Psaty, B.M., Qi, L., Quertermous, T., Raitakari, O.T., Rankinen,
T., Rauramaa, R., Ridker, P.M., Rioux, J.D., Rivadeneira, F., Rotter, J.I., Rudan, I., den Ruijter, H.M.,
Saltevo, J., Sattar, N., Schunkert, H., Schwarz, P.E., Shuldiner, A.R., Sinisalo, J., Snieder, H., Sørensen,
T.I., Spector, T.D., Staessen, J.A., Stefania, B., Thorsteinsdottir, U., Stumvoll, M., Tardif, J.C., Tremoli, E.,
Tuomilehto, J., Uitterlinden, A.G., Uusitupa, M., Verbeek, A.L., Vermeulen, S.H., Viikari, J.S., Vitart, V.,
Völzke, H., Vollenweider, P., Waeber, G., Walker, M., Wallaschofski, H., Wareham, N.J., Watkins, H.,
Zeggini, E., CHARGE Consortium (Gieger, C., Meisinger, C., Prokisch, H., Wichmann, H.-E.), DIAGRAM
Consortium (Klopp, N., Meyer, J.), GLGC Consortium, Global BPgen Consortium (Döring, A.), ICBP
Consortium (Meitinger, T.), MAGIC Consortium, Chakravarti, A., Clegg, D.J., Cupples, L.A., Gordon-Larsen,
P., Jaquish, C.E., Rao, D.C., Abecasis, G.R., Assimes, T.L., Barroso, I., Berndt, S.I., Boehnke, M., Deloukas,
P., Fox, C.S., Groop, L.C., Hunter, D.J., Ingelsson, E., Kaplan, R.C., McCarthy, M.I., Mohlke, K.L.,
O'Connell, J.R., Schlessinger, D., Strachan, D.P., Stefansson, K., van Duijn, C.M., Hirschhorn, J.N.,
Lindgren, C.M., Heid, I.M.°, North, K.E.°, Borecki, I.B.°, Kutalik, Z.°, Loos, R.J.°: The influence of age and
sex on genetic associations with adult body size and shape: A large-scale genome-wide interaction study.
PLoS Genet. 11:e1005378 (2015)
Wittenbecher, C., Mühlenbruch, K., Kröger, J., Jacobs, S., Kuxhaus, O., Floegel, A., Fritsche, A., Pischon,
T., Prehn, C., Adamski, J., Joost, H.-G., Boeing, H., Schulze, M.B.°: Amino acids, lipid metabolites, and
ferritin as potential mediators linking red meat consumption to type 2 diabetes. Am. J. Clin. Nutr. 101,
1241-1250 (2015)
Wolf, M., Riedlinger, I., Lehmann, R., Häring, H.-U., Schleicher, E., Peter, A.°: Comparison of the
automated KRYPTOR chromogranin A assay with the DAKO ELISA. Clin. Lab. 60, 2103-2106 (2014)
Würtz, P.°, Havulinna, A.S., Soininen, P., Tynkkynen, T., Prieto-Merino, D., Tillin, T., Ghorbani, A., Artati, A.,
Wang, Q., Tiainen, M., Kangas, A.J., Kettunen, J., Kaikkonen, J., Mikkilä, V., Jula, A., Kähönen, M.,
Lehtimäki, T., Lawlor, D.A., Gaunt, T.R., Hughes, A.D., Sattar, N., Illig, T., Adamski, J., Wang, T.J., Perola,
M., Ripatti, S., Vasan, R.S., Raitakari, O.T., Gerszten, R.E., Casas, J.P., Chaturvedi, N., Ala-Korpela, M.,
Salomaa, V.: Metabolite profiling and cardiovascular event risk: A prospective study of three
population-based cohorts. Circulation 131, 774-785 (2015)
Xie, T.Y., Ngo, S.T., Veldhuis, J.D., Jeffery, P.L., Chopin, L.K., Tschöp, M.H., Waters, M.J., Tolle, V.,
Epelbaum, J., Chen, C.C., Steyn, F.J.: Effect of deletion of ghrelin-o-acyltransferase on the pulsatile release
of growth hormone in mice. J. Neuroendocrinol. 27, 872-886 (2015)
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Publication List 2015
#
joint first authors
° corresponding authors
HMGU authors are given in bold letters
German Center for Diabetes Research
Xu, T., Brandmaier, S., Messias, A.C., Herder, C., Draisma, H.H., Demirkan, A., Yu, Z., Ried, J.S., Haller,
T., Heier, M., Campillos, M., Fobo, G., Stark, R.G., Holzapfel, C., Adam, J., Chi, S., Rotter, M., Panni, T.,
Quante, A.S., He, Y., Prehn, C., Römisch-Margl, W., Kastenmüller, G., Willemsen, G., Pool, R., Kasa, K.,
van Dijk, K.W., Hankemeier, T., Meisinger, C., Thorand, B., Ruepp, A., Hrabě de Angelis, M., Li, Y.,
Wichmann, H.-E., Stratmann, B., Strauch, K., Metspalu, A., Gieger, C., Suhre, K., Adamski, J., Illig, T.,
Rathmann, W., Roden, M., Peters, A., van Duijn, C.M., Boomsma, D.I., Meitinger, T., Wang-Sattler, R.°:
Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes. Diabetes
Care 38, 1858-1867 (2015)
Yin, P., Lehmann, R., Xu, G.: Effects of pre-analytical processes on blood samples used in metabolomics
studies. Anal. Bioanal. Chem. 407, 4879-4892 (2015)
Yousri, N.A., Kastenmüller, G., AlHaq, W.G., Holle, R., Kääb, S., Mohney, R.P., Gieger, C., Peters, A.,
Adamski, J., Suhre, K., Arayssi, T.°: Diagnostic and prognostic metabolites identified for joint symptoms in
the KORA population. J. Proteome Res. 15, 554-562 (2016) [published online 2015]
Zeller, T.°, Haase, T., Müller, C., Riess, H., Lau, D., Zeller, S., Krause, J., Baumert, J.J., Pless, O., Dupuis,
J., Wild, P.S., Eleftheriadis, M.S., Waldenberger, M., Zeilinger, S., Ziegler, A., Peters, A., Tiret, L., Proust,
C., Marzi, C., Münzel, T., Strauch, K., Prokisch, H., Lackner, K.J., Herder, C., Thorand, B., Benjamin, E.J.,
Blankenberg, S., Koenig, W., Schnabel, R.B.: Molecular characterization of the NLRC4 expression in relation
to interleukin-18 levels. Circ. Cardiovasc. Genet. 8, 717-726 (2015)
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