Newsletter March 2014
Transcription
Newsletter March 2014
ERN WIS CO AST E TH N IO NO R Newsletter AL ASSOC IAT DIC ME N VETERINAR N I Y S March 2014 Rabid – A Wisconsin Tale A Twist of Fate The traditional medical teaching was that “rabies is universally fatal once symptoms develop.” Things have changed a lot over the last 10 years with our understanding of rabies. Thanks to a Wisconsin patient and her doctor, rabies is no longer considered 100 percent fatal. A teenager from Fond du Lac, Jeanna Giese, made history in 2004 after she became the first known unvaccinated survivor of clinical rabies. She received an experimental treatment, now known as the Milwaukee protocol, involving a medically induced coma and course of anti-viral drugs that was pioneered at the Children’s Hospital of Wisconsin in Milwaukee. Prior to 2004, there had been only five documented survivors of symptomatic rabies and all had either been rabies vaccinated prior to exposure or received postexposure prophylaxis. Simply the act of surviving rabies is remarkable, but to have a neurologically functional outcome is remarkable. After being released from intensive care, Jeanna spent months in the hospital and in a rehabilitation facility relearning how to perform basic functions like speaking, standing and walking. She was able to go home at the beginning of 2005 and although some neurologic deficits still persist they have not stopped her from achieving her goals. In May 2011, Jeanna graduated from Lakeland College in Sheboygan, WI with a bachelor’s degree. One of her hobbies is sled dog racing with her team of Siberian Huskies. Jeanna is also an advocate for rabies education; she talks with school children about rabies safety and the importance of vaccinating their pets and is an Ambassador for the Global Alliance for Rabies Control. In Wisconsin in 2004 there were ten confirmed cases of rabies. This included eight bats, one skunk and one person, Jeanna Giese. In Wisconsin in 2013 there were 30 confirmed rabies cases, all in bats. In a twist of fate, one of those rabies positive bats was submitted by Jeanna Giese. She found the dead bat covered in bite marks in an enclosure with two of her Siberian Huskies. The bat was submitted to the Wisconsin State Laboratory of Hygiene which confirmed a positive rabies test. Fortunately there was no human contact (Jeanna collected the bat with a shovel and bags) and her dogs were rabies vaccinated. Her family veterinarian, Dr. Kim Everson of St. Bernard’s Animal Medical Center in Van Dyne, WI boosted her dogs’ rabies vaccinations and per Wisconsin state statutes the dogs were on home quarantine for 60 days. Jeanna’s encounter with rabies in 2013 was much less eventful than the one nine years ago. The Milwaukee Protocol In her first and most serious encounter with rabies, Jeanna Giese was only 15 years old when she found a bat in her Fond du Lac church. As an animal lover, she picked it up to carry it outside and was bitten on the finger. The wound was cleansed but due to a lack of awareness of any public health concern, the bat was not submitted for rabies testing. Jeanna was asymptomatic while the rabies virus traveled from the bite wound up her peripheral nerves into her central nervous system. Thirty seven days after being bit, she developed flu-like symptoms which rapidly progressed. Rabies causes encephalitis. In people this often begins with symptoms of a mild illness (headache, muscle aches, lethargy, weakness, nausea, fever and pain or paresthesia at site of the bite) that progressively worsens within days with changes in mentation (anxiety, insomnia, hallucinations) and neurologic deficits. The classic rabies symptoms of hydrophobia and hypersalivation are due to dysphagia. The disease progresses with hyperthermia, convulsions and death often occurs due to dysautonomia. Prior to Jeanna’s case, the most modern medicine could offer a clinical rabies patient was palliative end of life care with sedatives and analgesics. In Jeanna’s case, the diagnosis of rabies was made less than a week after the onset of her continued on page 2 1 symptoms via exRabid Continued from page 1 clusion of other causes of encephalitis and with confirmatory testing by the CDC of rabies. Antemortem testing that is utilized for diagnosis of rabies in people includes virus-specific antibody in the CSF and serum, nuchal skin biopsy antigen testing of cutaneous nerves and virus isolation on salivary samples. Dr. Rodney Willoughby, Jr. and his colleagues at the Children’s Hospital of Wisconsin in Milwaukee who were caring for Jeanna offered either hospice care or an experimental treatment to the Giese family. The treatment was based on the hypothesis that rabies mortality occurs not from neuronal cell death (from viral or immune-mediated cytopathic effects) but from temporary neurotransmission dysfunction. An excitotoxicity causes the neurons to rapidly deplete their supplies of nutrients leading to dysfunction. If one could protect the brain until neutralizing antibody levels were developed by the immune system a patient could potentially survive rabies. This treatment was consented to by the family even though there were no guarantees about what kind of quality of life a rabies survivor would have. The original Milwaukee protocol used on Jeanna involved a medically induced coma with antiviral drugs. Jeanna was on a ventilator and in a coma for six days. The sedatives were weaned once signs of an immune response were noted. After rehabilitation, Jeanna has had a remarkable recovery; seven years after her initial diagnosis, Dr. Willoughby was in attendance at her college graduation. Details of the original case can be found in publication and online in the New England Journal of Medicine. Willoughby, RE; Tieves, KS; Hoffman, GM; Ghanayem, NS; Amlie-Lefond, CM; Schwabe, MJ; Chusid, MJ; Rupprecht, CE (June 2005). “Survival after treatment of rabies with induction of coma” New England Journal of Medicine 352 (24): 2508–14. The Milwaukee protocol has been used on 43 reported cases and has been modified based on additional rabies research and clinical data. Recommendations for symptomatic patients include neither providing rabies immunoglobulin (as this delays rabies antibodies in the CSF which are thought to be essential for survival) nor rabies vaccination as this may be detrimental to survival. It is now known that there are common 2 complications associated with rabies such as transient hyponatremia, arrhythmias and diabetes insipidus which are routinely monitored for and managed. The main treatments in the Milwaukee protocol are based on the hypothesis that there are three main pathways of rabies induced neuronal damage including: excitotoxity, BH4 deficiency and cerebral vasospasm. Ketamine is an NMDA antagonist which has shown anti-rabies activity in animal models. It is also thought that ketamine can help prevent the build-up of the excitotoxin quinolinic acid through NMDA blockade. Amantadine, besides its antiviral properties is also an NMDA antagonist. Rabies patients also often have an acquired tetrahydrobiopterin (BH4) deficiency in their CSF. BH4 is a cofactor for the synthesis of dopamine, norepinephrine, serotonin and melatonin. Interestingly, people can be born with a BH4 metabolic deficiency. Symptoms of this rare genetic disorder can overlap with some of the symptoms of rabies including poor muscle tone, movement disorders, inability to modulate body temperature, difficulty swallowing and seizures. Cerebral arterial spasms are thought to be from decreased nitric oxide synthase (NOS). BH4 is a cofactor for NOS. Cerebral arterial spasms can respond to calcium channel blockers. The Rabies Treatment Controversy In 2011, Precious Reynolds, an 8 year old Californian was bitten by a cat and underwent treatment with the Milwaukee protocol with a positive outcome. Unfortunately Jeanna’s and Precious’ successful outcomes are still the exception rather than the rule for clinical rabies treatment. According to the rabies registry through the Medical College of Wisconsin, to date there have been 43 attempts to treat rabies with the Milwaukee protocol with only 5 classified as survivors. Of those survivors, limited information is available on if they are still alive or what quality of life they have. This poor success rate has led the scientific community to ask why so few patients respond to treatment. One of the major presumptions of the Milwaukee protocol is that there is not direct neuronal damage, only neuronal dysfunction, which can be managed until an immune response is mounted. This presumption is controversial in the scientific community; some researchers have found cytopathic effects in cells induced with rabies virus. Even if the central premise of the Milwaukee protocol is questioned, we still can’t ignore the fact that a handful of people have now survived rabies after developing clinical symptoms. A determining factor may be differences in strain of wild rabies. Three of the survivors were bitten by bats and two by cats (which often carry the bat strain of the virus). There has been less success for treatment of canine strains of the virus. Survival may increase from being infected with a less virulent strain of the virus. The patient’s own immune systems may also hold a key to surviving rabies. Two of the survivors were early immune responders which is not typical for rabies cases. An early immune response may have begun clearing the virus even before treatment was initiated. There may be a unique genetic component to survivors’ immune systems or perhaps being bit on an extremity allows the immune system adequate time to respond as the virus slowly moves up peripheral nerves to the brain. Rabies is Preventable There is no controversy that rabies prevention is much more effective than rabies treatment. The World Health Organization (WHO) estimates that over 55,000 people die each year of rabies. Death rates are especially high in developing nations in Asia, Africa and nonurbanized areas of Latin America where there are no preventative programs in place. Dogs are the source of rabies in 99% of cases world-wide so vaccination and stray animal control are key factors in decreasing human exposure. People who are at risk are encouraged to be vaccinated. This includes those with potential exposure due to occupation (such as veterinarians and technicians) and people who travel or those living in rabies endemic areas. Pre-exposure rabies vaccinations are expensive but they are less expensive than post-exposure prophylaxis. Prevention is also more effective and economical than treatment of clinical rabies; one doctor estimated that for the cost of treating just one patient with the Milwaukee protocol, 10,000 vaccines could have been administered. Fortunately United States laws requiring rabies vaccinations for dogs (and cats) have limited human exposure to rabies significantly. According to the CDC, in the United States over 90% of animal cases of rabies in the US are from wildlife and there are now only 2-3 cases of human rabies each year rather than dozens. There needs to be an ongoing crusade for public awareness of the risks of rabies since it is preventable and post-exposure prophylaxis can be life-saving. As Jeanna Giese learned, it is easier to take precautions immediately after a possible exposure to a rabid animal than to ignore the risk since the new saying is that rabies is still almost always a fatal illness. If you are interested in listening to a fascinating account on the history of rabies and treatments over the years you can download the August 2013 Radiolab podcast “Rodney Versus Death” at www.radiolab.org For further information on rabies and prevention, please visit the CDC: www. cdc.gov/rabies/ and the World Health Organization at www.who.int/ rabies/en/ AAH One call does it all. Call MWI today! (800) 824-3703 www.mwivet.com your business • your success • our goal There is also mounting evidence that people may be able to develop natural rabies immunity. There was case in 2009 in Texas of a teenager who encountered bats in a cave two months before rabies symptoms developed but did not received any prophylactic treatment as she did not think she was bit. When symptoms developed, she tested positive for rabies but only developed mild symptoms. She needed no intensive care and was discharged from the hospital two weeks later. Three years later and over 3000 miles away from Texas, people in the Amazon have developed natural rabies antibodies. Research published in the 2012 Vol. 87 of The American Journal of Tropical Medicine and Hygiene “Evidence of Rabies Virus Exposure among Humans in the Peruvian Amazon” shows some people living in two communities in Peru survived being exposed to rabies virus without receiving treatment. After nearly twenty years of outbreaks of rabies from the resident vampire bat population, 11% of those in the study tested positive for rabies neutralizing antibodies. It was unknown from the study if these people were ever clinically symptomatic or not. 3 Symptoms of RBF include fever, chills, muscle aches, headache, and vomiting. A maculopapular rash on the limbs may be noted 24-48 hours after the onset of fever and can then be followed by polyarthritis. The incubation period is from 3-10 days. Death in untreated cases is around 10% and is often from development of endocarditis, myocarditis, meningitis, pneumonia or sepsis. Fortunately Rat Bite Fever is rare in the United States and is highly treatable with antibiotics (such as penicillins) when caught early. It is not a reportable disease. PAST-PRESIDENT Dr. Jessica Daul Riverside Animal Hospital 920-336-5090 Email: [email protected] TREASURER Dr. Ellen Hooker WDATCP-Division of Animal Health 715-256-0068 Email: [email protected] EXECUTIVE DIRECTOR Dr. Jennifer Cyborski Fox Valley Animal Referral Center 920-931-2VMA Email: [email protected] BADGER DISTRICT DIRECTOR Dr. Pete Gasper One Medicine 920-359-1182 Email: [email protected] FOX VALLEY DISTRICT DIRECTOR Dr. Stephanie Slavik Country View Animal Hospital 920-722-1518 Email: [email protected] LAKELAND DISTRICT DIRECTOR Dr. Melanie Goble Mishicot Veterinary Clinic 920-755-2115 Email: [email protected] 4 STERN WISC EA O H T NO R Contact the NEWVMA Office at: 920-931-2862 or e-mail: [email protected] VETERINAR Y N IO www.newvma.org IN NS AL ASSOC IAT DIC ME NEWVMA Office N3354 Meade Street Appleton, WI 54913 PACKERLAND DISTRICT DIRECTOR Dr. Jenny Knorr Riverside Animal Hospital 920-336-5090 Email: [email protected] WVMA DISTRICT REPRESENTATIVES Dr. James Ziegler Wolf River Veterinary Clinic 920-982-2733 Email: [email protected] Dr. Ann Sosalla Companion Animal Care 920-921-5199 Email: [email protected] Contact your NEWVMA district director directly or get in touch with the NEWVMA Office at [email protected] or leave a message at 920-931-2VMA. NS Membership Announcements & Congratulations NEWVMA welcomes Dr. Tara Johanek of Apple Valley Veterinary Clinic as a new member. Congratulations to the following veterinarians who have earned the 10 Year Membership Award: Dr. Jill Duch, Globe University Appleton Dr. Mark Pipkorn, St. Anna Veterinary Clinic The following veterinarians have been awarded the 25 Year Membership Certificate: Dr. Kelly Peters, Countryside Veterinary Service Dr. Scott Ruetten, DePere Veterinary Services Life Membership, which is an honor awarded to NEWVMA members of good standing 65 years and older, has been bestowed upon the following veterinarians: Dr. John Fountain, Manawa-Marion Veterinary Clinic Dr. Allen Lande Dr. Dennis Nyren, We Care Animal Hospital Dr. Gretchen Schmidt, Animal Eye Clinic VETERINAR IN Y AL ASSOC IAT DIC ME It is advised that people in contact with rats practice good hygiene including washing hands after handling and not eating or drinking around rodents. Anyone with suspicious symptoms should see their physician and alert them to ownership/exposure to rodents so appropriate testing and treatment can be sought. Since S. moniliformis is part of the natural respiratory flora of rodents, routine testing or treatment of rodents by veterinarians is not advised. PRESIDENT-ELECT Dr. Ruth Hanson Oak View Veterinary Hospital 920-468-6936 Email: [email protected] The NEWVMA Board is here to serve you, but we can only be as helpful as the feedback we get from our members. If you have an idea for a continuing education topic or a speaker you’d like to hear, let us know. If there is a fun activity or locale you think would make for an interesting NEWVMA social next year, send us a line. If there is a serious local or state issue that affects you professionally and you would like NEWVMA and the WVMA to become involved, please share your thoughts and concerns. STERN WISC EA O TH Rat-bite Fever RBF is caused primarily by Streptobacillus moniliformis, a gram-negative bacillus. S. minus has been associated with RBF cases in Asia. Both of these bacteria are part of the normal respiratory flora of rats (and can also be found in other rodents such as mice and gerbils) and can be transmitted to people via bites or scratches. Cases have also been reported to occur from simply handling an infected rodent without any bites or scratches or ingesting contaminated food and drink. Person-to-person transmission has not been reported. PRESIDENT Dr. Ron Biese Kaukauna Veterinary Clinic 920-766-1237 Email: [email protected] Contact Us NO R Around half a million households in America have a rat or mouse as a pet. Rat fanciers praise rats as affordable pets that are sociable, intelligent animals with distinct personalities. Recently rat ownership has been in the news in a negative light with reports of a family suing Petco for the death of their ten-year old son from ratbite fever. 2014 NEWVMA BOARD of DIRECTORS N IO Rat-Bite Fever Correction The January 2014 NEWVMA Newsletter should have read on page 6 “Thank you to Dr. Frank Shearer for his ongoing support of the NEWVMA Scholarship Fund. He has made another contribution as a Silver Level Donor. His ongoing support helps NEWVMA support deserving veterinary students.” NEWVMA Will Pay for Published Articles Have you recently seen an interesting patient that would make a great case summary? Do you have a humorous veterinary anecdote to tell? Is there a timely public health issue, medical advance or veterinary-related humaninterest story that would be worth sharing with others? NEWVMA will pay $50 for each fulllength (minimum one page including any pictures) article or $25 for each shorter article that is accepted for publication in the newsletter. Articles may be edited for publication. Please e-mail the article and any related photographs to [email protected] for consideration. 5 Refresh Your Memory – Reportable Infectious Diseases in Wisconsin There are a list of reportable diseases that veterinarians who work with those species in Wisconsin should be knowledgeable about. The diseases are legally reportable to the Department of Agriculture, Trade and Consumer Protection (DATCP) for the protection of the public, monitoring of animal health, eradication programs and/or for the safety of agriculture in the state. Suspected or confirmed cases are legally required to be reported. Per state law if the WVDL or the State Lab of Hygiene tests a sample that is positive for a reportable disease they will make the report to the DATCP; in that case the referring veterinarian is not also required to do so. If you have a suspected or confirmed reportable disease, during business hours (7:45 a.m.-4:30 p.m. weekdays), contact one of the following (do not leave a message, please make sure you speak directly with the contact person): • Wisconsin Division of Animal Health 608-224-4872 • U.S. Department of Agriculture Veterinary Services 608-662-0600 • A district veterinarian For diseases (suspected or confirmed) that must be reported within 24 hours the following numbers are to be used to report a veterinary emergency and only during non-business hours: • • • Wisconsin Emergency Management duty officer 1-800-943-0003 Wisconsin State Veterinarian 262740-0574 USDA Veterinary Service Area Veterinarian in Charge 608-3346811 Diseases to be Reported within One Day Foot and mouth disease Bluetongue Vesicular conditions including vesicular stomatitis Equine encephalomyelitis (Eastern and Western) Swine vesicular disease African horse sickness Rinderpest African swine fever 6 Peste des petits ruminants Classical swine fever Contagious bovine pleuropneumonia Avian influenza Lumpy skin disease Viscerotropic velogenic Newcastle disease Rift Valley fever Sheep pox and goat pox Pseudorabies (Aujesky’s disease) Brucellosis Rabies Tuberculosis Pullorum disease Mycoplasma meleagridis Chronic wasting disease Any disease that is a foreign or exotic disease to Wisconsin Diseases to be Reported within 10 Days Multiple species diseases Anthrax Echinococcosis/hydatidosis Heartwater Leptospirosis New world screwworm (Cochliomyia hominivorax) Old world screwworm (Chrysomya bezziana) Paratuberculosis also known as Johne’s Disease Q Fever Fish diseases Channel catfish virus Enteric septicemia of catfish Epizootic hematopoietic necrosis Infectious hematopoietic necrosis Largemouth bass virus Mycobacteriosis infection Oncorhynchus masou virus disease Proliferative kidney disease Spring viremia of carp Streptococcus iniae Viral hemorrhagic septicemia Whirling disease (Myxobolus cerebralis) White sturgeon iridovirus Sheep and goat diseases Caprine and ovine brucellosis (excluding B. ovis) Caprine arthritis/encephalitis Contagious agalactia Contagious caprine pleuropneumonia Enzootic abortion of ewes (ovine chlamydiosis) Maedi-visna Nairobi sheep disease Ovine epididymitis (Brucella ovis) Ovine pulmonary adenomatosis Salmonellosis (S. abortusovis) Scrapie Division of Animal Health Ve t e r i n a r i a n S t a f f Wisconsin Department of Agriculture, Trade & Consumer Protection 7/25 /20 12 Contacts for Central Office: Dr. Bourie, supervisor Melissa Mace, Bureau Dir DATCP - Reception USDA - Reception Swine diseases Atrophic rhinitis of swine Enterovirus encephalomyelitis Porcine cysticercosis Porcine reproductive and respiratory syndrome Transmissible gastroenteritis Trichinellosis (608) 224-4886 (608) 224-4883 (608) 224-4872 (608) 662-0600 Bayfield Douglas Ashland Iron Vilas Bee diseases Acariosis of bees American foulbrood European foulbrood Nosemosis of bees Varroosis Washburn Burnett Sawyer Florence Tom Varty - USDA (715) 933-1202 cell Polk Lagomorph diseases Myxomatosis Rabbit hemorrhagic disease Oneida Price Rusk Barron Forest Timothy DeVeau - USDA (715) 536-4534 (715) 432-2152 cell Lincoln Taylor Marinette Langlade Chippewa Saint Croix Cattle diseases Bovine anaplasmosis Bovine babesiosis Bovine spongiform encephalopathy Bovine cysticercosis Bovine genital campylobacteriosis Infectious bovine rhinotracheitis/infectious pustular vulvovaginitis Dermatophilosis Enzootic bovine leukosis Hemorrhagic septicemia Malignant catarrhal fever Theileriosis Trichomonosis Trypanosomosis (tsetse-borne) Door Marathon Ellen Hooker - DATCP (715) 256-0068 (608) 516-9131 cell Shawano Pierce Clark Eau Claire Pepin Kewaunee Portage Wood Buffalo Waupaca Brown Outagamie Jackson Trempealeau Libby Balzer - DATCP (608) 269-0604 (608) 516-9128 cell Waushara Manitowoc Calumet Winnebago Lake Winnebago Monroe La Crosse Juneau Dick Bertz - USDA (608) 444-3546 cell Adams Marquette Fond du Lac Green Lake Sheboygan Vernon Columbia Sauk Richland Dodge Washington Ozaukee Crawford Equine diseases Contagious equine metritis Dourine Epizootic lymphangitis Equine infectious anemia Equine influenza Equine piroplasmosis Equine herpes virus Equine viral arteritis continued on page 8 Oconto Menominee Dunn Erika Doescher- DATCP (608) 516-9127 cell Dane Jefferson Iowa Waukesha Grant Racine Lafayette Green Rock Walworth Dennis Foelker - DATCP (920) 261-5584 (608) 225-5490 cell Milwaukee Shelby Molina - DATCP (262) 473-3757 (608) 516-9125 cell Kenosha Kim Kessenich - USDA (608) 444-5047 cell I:\Library\MAPS\AH_Vets_Map.pdf 7 Pet Jerky Treat Investigation Update Fowl pox Fowl typhoid Marek’s disease Infectious bursal disease (Gumboro disease) Diseases Continued from page 6 Glanders Horse mange Horse pox Japanese encephalitis Surra (Trypanosoma evansi) Venezuelan equine encephalomyelitis Avian diseases Avian infectious bronchitis Avian infectious encephalomyelitis Avian infectious laryngotracheitis Avian mycoplasmosis (M. gallisepticum) Avian tuberculosis Duck virus enteritis Duck virus hepatitis Fowl cholera Ornithosis (psittacosis) Paramyxovirus infections of poultry other than Newcastle disease Salmonellosis Infectious laryngotracheitis Chicken jerky treats originating from China have been causing pets to become ill. The FDA first put out a warning to pet owners in 2007 and has recalled certain brands, but jerky products are still being sold and illnesses are still being reported. The FDA has had over 3,000 reports of pet illness that may be related to jerky treats; this includes more than 3,600 dogs, 10 cats and includes more than 580 deaths. Testing is also being extended beyond chicken jerky to include duck, dried fruit, sweet potato and yam jerky treats. Mollusc diseases Haplosporidiosis (H. nelsoni or H. costale) Bonamiosis Marteiliosis Mikrocytosis (Mikrocytos mackini) Perkinsosis The FDA is working with laboratories across the country to investigate causes but thus far testing for contaminants in jerky pet treats has not revealed a cause for the illnesses. The following have been ruled out with negative testing: Salmonella, metals and elements such as arsenic, cadmium and lead, markers of irradiation level (such as acyclobutanones), pesticides, antibiotics (including both approved and unapproved sulfanomides and tetracyclines), mold and mycotoxins, rodenticides, nephrotoxins (such as aristolochic acid, maleic acid, paraquat, ethylene glycol, diethylene glycol, toxic hydrocarbons, melamine, and related triazines) and endotoxins. Diseases of other animal species Leishmaniasis Thank You We appreciate the opportunity to supply your practice with all that it takes to care for the needs of your patients. Like you, we are always looking for ways to better serve our customers. That’s why we have developed a multitude of business solutions that can help to grow your practice and build stronger relationships with your clients. Presenting Growing Solutions for Your Practice Stop by our booth at the May NEWVMA meeting to learn all about what Midwest Veterinary Supply can do for you! WWW.MIDWESTVET.NET I JAT PHARMS I JAT RX I MYVETSTOREONLINE.COM ECARD CONNECT I SARIS WEB DESIGN I THE VET APP 8 Pet owners should watch for signs that may occur within hours to days of ingestion including anorexia, lethargy, vomiting, diarrhea and polyuria/polydipsia. Severely affected cases are often diagnosed with pancreatitis, gastrointestinal bleeding and kidney failure including Fanconi-like Syndrome which can cause glucosuria, proteinuria, electrolyte abnormalities and metabolic acidosis. Fanconi-like Syndrome is an acquired disease most commonly caused by renal tubular toxicity. Fanconi Syndrome is a rare inherited disorder seen most commonly in Basenjis. Pet owners and veterinarians can report cases to the FDA either through their local FDA Consumer Complaint Coordinator or electronically through the FDA safety reporting portal online. Any packaging and samples of the treats should be held in case the FDA asks for submission for testing. The FDA states that although they do “not necessarily respond to every individual complaint submitted, each report becomes part of the body of knowledge that helps to inform FDA on the situation or incident.” What you can do to prevent issues: ■ Alert your clients to the possible dangers of jerky treats. A client warning can be shared from the NEWVMA Facebook page, downloaded from www.newvma.org or you can contact [email protected] for a Microsoft Publisher document you can customize with your own business logo to hand out to clients. What you should do if you suspect a case: ■ Perform routine blood work and urinalysis for diagnosis. Urinalysis should be performed even if only GI symptoms are noted. ■ Record the product information including lot number. ■ Submit an official report (see reporting information above). ■ Save additional samples for possible submission including: the treats, a frozen sample (10 mL if possible) of urine (if within 24 hours of ingestion) and frozen necropsy tissues. Since it has been difficult for the FDA to determine if jerky treats or other diseases are the cause of illness/death in reported cases, the Veterinary Information Network (VIN) and veterinary pathologists are helping with the investigation. If a veterinarian has a suspected case (where signs occur within four days of ingestion of a jerky treat) he or she may complete a survey on VIN. Veterinarians who are not members of VIN may call toll-free (800) 700-4636 to obtain a temporary login and password to access the survey. In some cases, veterinarians may also be asked to submit: samples of suspect jerky (provided the package lot number is available), frozen tissue samples from necropsies and urine from active cases when samples are collected within 24 hours of jerky treat ingestion. More than a pet to her. More than a sample to us. Locations in: Marshfield, WI; Milwaukee, WI; Madison, WI; Cleveland, OH; Akron, OH 1000 North Oak Avenue Marshfield, WI 54449 www.marshfieldlabs.org 9 In Memoriam — Dr. Quintin Metzig Dr. Quintin C. Metzig passed away on March 2, 2014. He was born on April 4, 1917, on his family’s homestead in Zittau, Wisconsin. His industrious German family farmed, hunted, trapped, fished, and gardened, making full use of the land. Quintin received his primary education in a one-room church school where the academic calendar revolved around planting and harvesting. His father frequently took him to school in a horse-drawn sleigh in winter. As a teenager, he boarded with a local family during the week so that he could attend Oshkosh High School. The day Prohibition was repealed, 16-year-old Quintin celebrated at John Brown’s, an Oshkosh bar that would later be renamed Oblio’s. As a student at the University of Wisconsin, he came home from Madison one Christmas, trapped 200 muskrats, and sold the pelts for $400- the total cost of his freshman year. He went on to Michigan State University, where he earned his degree in veterinary medicine and a number-one academic ranking. While working in the cafeteria at Michigan State his senior year, he met Jeanne Mosson of Ionia, Michigan, a junior studying home economics. By spring term, they were going on two dates a day. The two were married the day Jeanne graduated, in 1946. Quintin and Jeanne made their home in Oshkosh, where they had six children and worked diligently to raise their family and build Quintin’s veterinary practice- the only one in Winnebago County at a time when the county comprised more than 2,000 farmers. The bulk of Quintin’s work was with large farm animals, primarily cows. He was named Wisconsin Veterinarian of the Year in 1958 and became a well-known figure among local farmers in his 45 years as a veterinarian. Quintin was a devoted tree farmer who, over the course of his life, oversaw the planting of approximately 100,000 seedlings, many of which stand tall today. He was also a prolific grower of shiitake mushrooms, which he and Jeanne studied while traveling in Japan, one of many countries they visited together. In addition to travel, farming, and being a veterinarian, Quintin enjoyed driving his tractor, eating brick cheese and licorice, and going to lunch with his ROMEO (Really Old Men Eating Out) group every Wednesday. Quintin was involved in numerous charitable endeavors including being the major donor which helped found the NEWVMA Scholarship Fund which has awarded over $10,000 to third year University of Wisconsin veterinary students since it was started in 1997. In Dr. Metzig’s memory, NEWVMA will be donating $100 to the NEWVMA Scholarship Fund. Limited Seats Still Available for Dentistry CE NEWVMA has invited Animal Health International to the Fox Valley area to provide veterinarians and technicians up to 16 hours of CE credit with lectures and hands on laboratories under the guidance of two board certified veterinary dentistry specialist, Dr. Brooke Niemiec and Dr. Dale Kressin. On Saturday and Sunday, April 12th and 13th, 2014 there will be lectures on oral pathology, periodontal disease and therapy, dental radiology and interpretation, dental extractions and veterinary dentistry marketing. The wet labs will include hands on dental radiology, prophylaxis, extractions, bonded sealants, clindoral and regional anesthesia. The technician wet lab is full. There are still a limited number of seats available for the veterinarian wet lab as well as the lectures for both veterinarians and technicians. To register (or if you would like to be placed on the waiting list) contact Tom Knutson at [email protected] or 970-347-3217. A registration link for this program is available at www.newvma.org In Memoriam — Dr. James Walsdorf James A. “Doc” Walsdorf, 86, formerly of St. Anna, passed away last year, March 10, 2013. He was born October 24, 1926, in St. Anna, son of the late Dr. I.A. & Johanna (Wollner) Walsdorf. Doc attended St. Ann Catholic School and was a 1945 graduate of Kiel High School. After finishing his undergraduate studies he attended Kansas State University and was a 1956 graduate of The College of Veterinarian Medicine. In June of 1956, Doc began his career as a large animal veterinarian at the St. Anna Veterinarian Clinic, which his father founded in 1921 . He continued his practice until his retirement in 1987. Doc was an active and lifetime member of many veterinarians associations, including NEWVMA, and was recognized by the WVMA for his 50 years of service to his profession. He took great pride in the work he did, especially helping many young veterinarians get started by offering his home and clinic while they completed their internship. On August 17, 1957, he was united in marriage to Ruth Bradley at St. Peters Catholic Church in Oshkosh. Doc was a member of St. Ann Catholic Church, St. Anna. He was a proud supporter and active member of many organizations in the community, including, New Holstein St. Vincent DePaul, Knights of Columbus and the St. Anna Sportsmen Club. He was a 50 year, charter member of the East Shore Lions Club holding many offices throughout the years. Doc served as Bank Director to Marytown Bank and later M&I Bank. He also enjoyed his time volunteering as a Meals on Wheels driver and doing patient transportation. He was a founding member of the Men’s Breakfast Club at Calumet Homestead and served on the CPES School Board for many years. He was also a 56 year member of the Night Crawlers Card Club. A Gift of a Lifetime Oral Histories in Veterinary Medicine by Fred J. Born, DVM We all know of an associate, colleague, mentor or friend that is a veterinarian who is in their 70s, 80s or even in their 90’s. A recent survey conducted by the American Veterinary Medical History Society revealed that this age group had experienced the greatest change in one generation in the history of our profession. It is suggested, if anyone would be interested in conducting an interview of a veterinarian who would be willing to share his professional story, it would be a gift of a lifetime. What a great gift-- a transcribed, written record of that interview to accompany the spoken word for this veterinarian and his/her family to cherish for generations to come. Next year the WVMA will be celebrating their 100th Anniversary 1915 – 2015. It will be an exciting year, reviewing the great history of the WVMA and featuring some of the outstanding WVMA members in our local communities and including our own leaders on the state and the national scene. Anyone who would be interested in this very rewarding experience need only download the interview guide and some examples of oral histories in veterinary medicine. To do this, just email: Dr. Fred J. Born fjborn@att. net and request the complete information. In his early days he coached his daughter’s softball teams, loved tailgating and watching Packers and Brewers games. He found great comfort and relaxation at the family cottage on Wilkes Lake and at the cabin in northern WI. In his retirement, he also enjoyed his many travels with Ruth. Doc loved his time spent golfing, bowling, sturgeon fishing, and deer hunting, especially bow hunting. Above all else, doc most enjoyed the time he spent with his family, especially his wife , children and grandchildren. In Dr. Walsdorf’s memory, NEWVMA will be donating $100 to the NEWVMA Scholarship Fund. 10 11 Tired of Winter? Upcoming Events and Continuing Education Opportunities MARCH Friday March 28 Clarifide Genomic Technology – Key Learnings and Applications of a Game Changing Technology 4 CE hours* 10 am, Liberty Hall, Kimberly, WI RSVP to Cheryl Marti at 608-206-0635 or [email protected] APRIL Looking forward to spending time outside in the sunshine and fresh air? Then join us for the NEWVMA Spring Social on June 14th! Save the Date! NEWVMA is hosting our Spring Social on Saturday, June 14th at the Galloway House & Village in Fond du Lac, WI. There will be activities and food available from 11 am to 3 pm as your family strolls the grounds, including guided tours of the Veterinary Museum. The Fred J. Born Veterinary Office is one of only 28 veterinary Saturday and Sunday April 12-13 Small Animal Dental Lecture and Wet Lab for Veterinarians and Technicians Appleton, WI Earn up to 16 CE hours. Registration Details Inside! historical museums in the country. It includes hundreds of items of veterinary historical MAY shop with working equipment and many more century-old structures to take you back The rest of the Galloway House & Village grounds are also available for you to explore. They include: the famous 30-room Galloway Victorian mansion, a school house, a print 100 years. Proceeds from the NEWVMA Spring Social will benefit maintenance and upkeep for the Veterinary Museum at the Galloway House & Village. Help support a good cause and enjoy the company of your fellow veterinary professionals--stay tuned for details! Northeastern Wis. Veterinary Medical Association N3354 Meade St. Appleton, WI 54913 Tuesday May 20 Veterinary Medicine in the 21st Century: Strategies for Success Now and in the Future 6 CE hours* Appleton, WI Registration Details Inside! *CE credits provided by NEWVMA significance from old surgical texts and diagrams to antique diplomas and tools.