Preliminary Program
Transcription
Preliminary Program
Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 Scan the code with your smart phone to go directly to SLAS2012.org. Premier Sponsor: Preliminary Program Register by December 12 for Maximum Savings! SLAS2012—the First Annual SLAS Conference and Exhibition—unites the scientific savvy, innovation and energy of the former LabAutomation and SBS conferences to increase collaboration and prominence for the laboratory science and technology community. An Exceptional Line-up of Industry Visionaries: Peter G. Schultz, Ph.D. Jing Cheng, Ph.D. Robert Ballard, Ph.D. Scripps Family Chair Professor, Department of Chemistry, The Scripps Research Institute Member, Chinese Academy of Engineering; Director, National Engineering Research Center for Beijing Biochip Technologies; CEO, CapitalBio Corporation; Cheung Kong Professor, Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing, China Professor, University of Rhode Island (URI) Graduate School of Oceanography; Founder and President, Institute for Exploration (IFE) at Mystic Aquarium, Mystic, Connecticut Monday, February 6 Presentation: A Chemist’s Foray Into Translational Medicine Tuesday, February 7 Presentation: Biochips for Translational Medicine Wednesday, February 8 Presentation: Deep Sea Science and Exploration HERE’S JUST A BIT ABOUT WHAT COMES YOUR WAY ALL 365 DAYS: EVENTS AND EDUCATION JOURNALS THE MARKET PLACE ELN Annual Conferences and Exhibitions (US, Asia and beyond), Virtual Courses and SLAS On-Demand all provide content-rich scientific education. SLAS members receive significant registration discounts. Two award-winning internationally recognized peer-reviewed scientific journals— The Journal of Laboratory Automation (JALA) and the Journal of Biomolecular Screening (JBS). The ultimate online product directory with quick-andeasy access to an everexpanding collection of new and existing technology products and services for the laboratory. The SLAS Electronic Laboratory Neighborhood (ELN), an innovative e-zine that is people focused and people sourced, is available 365/24/7 at SLAS.org. JOIN OR RENEW AT SLAS.ORG! FOR DETAILS ON INDIVIDUAL AND CORPORATE MEMBERSHIPS, CONTACT: [email protected] | +1.630.256.7527 Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org “I’m looking forward to the new technologies! Having access and being introduced to the latest innovation in the marketplace is imperative to what I do. With so many exhibitors showcasing their products and services in one place, SLAS2012 is the perfect opportunity for me to get a broad overview of what’s new. And with SLAS now expanding into Asia, it’s exciting to be part of a global organization.” Ying Yang, Managing Director, LBD Life Sciences Limited China Table of Contents ºº What’s Moving You to SLAS2012?Page 4 ºº Short Courses OverviewPage 5 ºº Keynote Speaker SeriesPage 8 ºº Conference-at-a-GlancePage 9 ºº Conference SchedulePage 11 ºº Strategic Alliances at SLAS2012Page 18 ºº Celebrate InnovationPage 19 ºº SLAS2012@NightPage 20 ºº Experience a Robust and Lively ExhibitionPage 21 ºº Exhibitor ListPage 22 ºº Travel and Hotel InformationPage 23 ºº SLAS Career ConnectionsPage 25 SLAS2012 Annual Conference Program Committee, SLAS Scientific Program Advisory Committee, SLAS Board of Directors Page 26 ºº Sponsors and Media Partners That Make SLAS2012 Possible! Page 27 ºº Conference and Short Course Registration Form ºº Page SLAS goes mobile December 1. Try us out on your smart phone! 3 | SLAS2012.org 29 Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org What's Moving You to SLAS2012? SLAS2012 is the moment in time when we all come together as a community to collaborate, innovate and dominate the field of laboratory science and technology. Join 5,000+ of your colleagues — innovative scientists, engineers, researchers and technologists from academic, government and commercial laboratories around the world — in beautiful San Diego, CA, USA, February 4–8, for SLAS2012. “I am most looking forward to the expansive format of the meeting; several days of conference with more than 130 presenters, hundreds of posters, and a variety of special sessions — I think the event is going to be outstanding.” Dan Harms, Automation Engineer, Syngenta Biotechnology Inc. Accelerate Celebrate With over 130 podium presentations, 300+ poster presentations, influential keynote speakers, and a strong short course program covering an array of topics in-depth, SLAS2012 packs a powerful scientific punch. Kick back, relax and mingle each night while you’re in San Diego with hundreds of your SLAS2012 colleagues at these three prime evening events: Content-Rich Scientific Program Accelerates Learning and Professional Growth Collaborate Collaborate with others in your area of interest and expertise by joining an SLAS Special Interest Group (SIG) at SLAS2012, visit, SLAS.org/community/special_interest.cfm. Examples of organized SLAS SIGs include: ºº ºº ºº Automation Quality Control Drug Repurposing Screen Design and Assay Technology Standards Initiatives — New! To be considered for participation, contact Katie Woywod at [email protected] by November 18. SLAS has partnered with several leading scientific organizations to bring you new and relevant sessions and informational briefings at SLAS2012. Partner sessions include: ºº Elevate Career Advisory and Networking Events Learn how to effectively network with professionals; work one-on-one with a career coach; have your résumé critiqued; participate in mock interviews; strategize for the job market; and have access to current job opportunities in the marketplace at the SLAS Career Center. SLAS Smart-Savers Program Helps Get You There Strategic Alliances Bring Special Sessions to SLAS2012 ºº ºº Sunday, February 5 — Super Bowl After-Party Monday, February 6 — Monday Night Diamond Groove-a-Thon Tuesday, February 7 — Gaslamp Block Party Bash Motivate Stimulate ºº ºº ºº SIGs to Meet at SLAS2012 ºº SLAS2012@Night Offers Good Times, Great Networking and an SLAS Community Feel Early-bird, SLAS member and group registration discounts. Special hotel pricing. 20 percent off a Sunday short course with the purchase of a Saturday course. Academic and unemployed registration waivers. The SLAS2012 SmartSavers Program provides myriad ways to help you get to San Diego, visit SLAS2012.org/conference/smartsavers.cfm. Facilitate Analytical and Life Science Systems Association Laboratory Products Association Late Night With LRIG Get Employer Approval for SLAS2012 Investigate Experience a Robust and Lively Exhibition See, hear, touch, feel and engage with some of the latest and most innovative technology products and services from around the world when you explore the SLAS2012 exhibit floor. With over 275 companies housed in 500+ booths, SLAS2012 provides the ultimate hands-on experience. Don’t simply ask your employer to approve “your trip” to SLAS2012. Rather, present them with a sound business case that rationally justifies “your participation” by illustrating the benefits they can expect to receive in return for their investment. To get more tips and tools and specific examples of appropriate rationales to sell your participation at SLAS2012, visit SLAS2012.org/conference/employerapproval.cfm. 4 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Accelerate | Short Courses Overview The SLAS2012 Short Course Program provides in-depth instruction on topics, issues and techniques related to the laboratory science and technology community. Each course is a full day and is led by distinguished faculty with deep expertise in their respective course topic. Each course is organized separately, though individuals will benefit from attending two days of short courses. Short Course registration is an additional fee. Short Course only registration is also available. For additional information on the Short Course Program, visit SLAS2012.org/program/shortcourses.cfm Short Course Discount for Members: Save 20 percent on a Sunday short course by purchasing a Saturday course. This discount is already calculated in the price of the course. Saturday, February 4, 2012, 8:30 am – 4:30 pm Applied Information Technology for the Laboratory Introduction to Laboratory Automation Burkhard Schaefer, BSSN Software This course provides decision makers and practitioners from bio-pharma, healthcare, and academia with a comprehensive overview of IT topics and trends in laboratory automation, data management, and systems integration. Steven D. Hamilton, SLAS Director of Education; Gary W. Kramer, National Institute of Standards and Technology; James M. Gill II This course presents a broad introduction to the field of industrial (i.e. non-clinical) laboratory automation. A general understanding of a laboratory environment is helpful. Automated Liquid Handling in Accredited or Forensic Environments LIMS in the Organization Michael Stangegaard, University of Copenhagen; Anders Johannes Hansen, University of Copenhagen This course presents an introduction to the process of standardizing, validating and accrediting automated liquid handling instruments and processes in both conventional and forensic environments. Automation for In Vitro Diagnostics Angelika Niemz, Keck Graduate Institute; Jim Osborne, Keck Graduate Institute In vitro diagnostics (IVD) entails the diagnosis, screening, and monitoring of human diseases based on identification and quantification of small molecules, proteins, nucleic acids, or cells obtained from patient specimens. Automation has fundamentally changed the IVD industry, and continues to play an important role in the move towards disseminated testing and personalized medicine. Electronic Laboratory Notebooks John Trigg, phaseFour Informatics This course outlines the role of an Electronic Laboratory Notebook, addressing functional and user requirements, legal and IP issues, cost/benefit and implementation strategies. Establishing Cell-Based Assays for Screening Terry Riss, Promega Corporation; Lisa Minor, In Vitro Strategies, LLC; Geoffrey Bartholomeusz, UT M.D. Anderson Cancer Center; Eric Johnson, Merck This course describes developing standard procedures for handling cultured cells to set up cell-based assays, techniques for measuring cell health, multiplexed with other assays, developing siRNA screening assays, and an overview of various GPCR screening methods. Robert D. McDowall, McDowall Consulting This course provides an overview of the system development life cycle of a LIMS and the identification of the common issues and problems associated with a project. Liquid Handling Boot Camp — A Beginner's Hands-On Introduction to Lab Automation Douglas Gurevitch, University of California, San Diego; Petar Stojadinovic̀, National University; Justin Provchy, Amgen, Inc. Learn about lab automation in a hands-on environment. One-third of the class time is lecture and two-thirds is hands-on work with the robots. Quantitative Evaluation of Screening Assays for Drug Discovery & Biomarker Applications V. Devanarayan, Abbott Laboratories; Eric Goedken, Abbott Laboratories This course provides an overview of methods useful for optimizing, evaluating, and analyzing in vitro screening assays for drug discovery and biomarker applications are provided. Sample Management: Best Practice, Trends and Challenges Sue Holland Crimmin, GlaxoSmithKline This course provides current status and considered best practice in the discipline of sample management. It will focus on the traditional aspects of compound management but cover the synergies and differences in managing biologics. Consideration will be given to key challenges and future directions. 5 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Sunday, February 5, 2012, 8 am – 3:30 pm Automated Assays for Drug Discovery: A Toolbox Approach to Selecting an Appropriate Assay Mohammed Kashem, Boehringer-Ingelheim Pharmaceuticals, Inc.; Siqi Lin, Boehringer-Ingelheim Pharmaceuticals, Inc. This course focuses on one central question: given a multitude of assay technologies available for a given target, how does one go about selecting an appropriate technology? What criteria should one examine during this process? This course describes a toolbox approach: a generic, flexible set of assay methodologies and shows how they can be applied to some of the major target classes in molecular and cell-based screening. Automating Scientific Data Analysis and Visualization With Excel and VBA Mark F. Russo, Bryn Mawr College; Stephen Carafello, Green Iguana Productions LLC This course explores advanced features of Excel 2007 and Excel 2010 useful to scientists and engineers. Topics covered include importing and processing experimental data, handling of data arrays, creation of custom user interfaces, curve fitting, and automatic generation of charts. High Content Screening: Instrumentation, Assay Development, Screening, Image and Data Analysis Eberhard Krausz, Janssen Research & Development; Stephan Schürer, University of Miami Medical School; Vance Lemmon, University of Miami; James G. Evans, Anon Consulting This course provides a state-of-the-art overview of the components of HCS (instrumentation, reagents, HC assay development, automated image analysis and multi-parametric data analysis, and data standards) together with some showcases of small molecule and RNAi high-content screens in industry and academia. Liquid Handling Boot Camp — A Beginner's Hands-On Introduction to Lab Automation Douglas Gurevitch, University of California, San Diego; Petar Stojadinovic̀, National University; Justin Provchy, Amgen, Inc. Learn about lab automation in a hands-on environment. One-third of the class time is lecture and two-thirds is hands-on work with the robots. Next Generation Sequencing Technologies and Automation Introduction Patrick Merel, University Hospital of Bordeaux This course provides an overview of the major Next Generation Sequencing (NGS) technologies, how to automate their workflow and what to expect from Next-Next Generation Sequencing upcoming technologies. Pharmacokinetics and Pharmacodynamics in Drug Discovery Terry Kenakin, University of North Carolina School of Medicine, Chapel Hill This course is designed to increase understanding of the fundamental concepts governing drug pharmacokinetics (ADME studies), safety pharmacology and therapeutic pharmacodynamics as they are utilized in new drug discovery. Technical Project Management Introduction to Design of Experiments Wayne J. Levin, Predictum Inc. This interactive, hands-on course allows students to exploit Design of Experiments (DOE) as soon as they get back to their workplace. The course uses Excel for the essentials and JMP software for more advanced, yet accessible, methodologies. Introduction to Laboratory Automation Steven D. Hamilton, SLAS Director of Education; Gary W. Kramer, National Institute of Standards and Technology; James M. Gill II This course presents a broad introduction to the field of industrial (i.e. non-clinical) laboratory automation. A general understanding of a laboratory environment is helpful. Label-Free/Biophysics Methods for Screening Johannes Ottl, Novartis Pharma NIBR; Delphine Collin, Boehringer-Ingelheim Pharmaceuticals, Inc.; Kristin Coan, Novartis Pharma AG This course focuses on those "biochemical" biophysics technologies with highest impact and applicability for screening and lead finding. This short course also focuses on biochemical assay applications and the detection, quantification and qualification of ligand/protein binding events. Jim Atkin, Invetech Pty Ltd Course objectives include: mapping the phases of a project; introducing specific project management tools; and discussing and demonstrating the application of these tools in the development and implementation of new technologies and processes for diagnostics, manufacturing and drug discovery. Writing Testable and Verifiable User Requirements Robert D. McDowall, McDowall Consulting This short course teaches a methodology for specifying the user needs of the instrument and software elements that will enable selection of the most appropriate system and end user testing to meet business and/or regulatory (e.g. GLP or GMP) needs. XML for the Laboratory Burkhard Schaefer, BSSN Software This computer-based short course provides an introduction to XML and examines how it can be used in a laboratory environment. Using a healthy mix of theory and hands-on exercises, it helps provide guidance when it comes to evaluating XML applications in the laboratory. 6 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Two-Day Short Courses Saturday, February 4, 2012, 8:30 am – 4:30 pm | Sunday, February 5, 2012, 8 am – 3:30 pm Getting Started With Excel and VBA in the Laboratory Microfluidics I/II William Neil; Martin Echols, Forest Laboratories Excel is widely used in scientific laboratories to automate tedious data manipulation and presentation tasks. This course reviews many of the tools built-in to Excel for handling problems commonly encountered in the laboratory. It also introduces the Visual Basic for Applications scripting language as a way to customize Excel and expand upon its functionality. Jörg P. Kutter, Technical University of Denmark; Johan Nilsson, Lund University; Sabeth Verpoorte, University of Groningen This course is an introduction to microfluidics and the application of this technology in the life sciences. It is designed to give a compact overview of the main important aspects of working with liquids in confined spaces as well as handling of minute amounts of chemicals, highlighting the essential differences between microfluidic-based approaches and more traditional biochemical analysis systems. The attendees receive a broad "first glimpse" impression of all the different bits and pieces (technological, physical and chemical) that are necessary to arrive at functional lab-on-a-chip devices. “It’s exciting to be part of an organization that is truly operating globally. I think SLAS2012 is going to be a fantastic representation of our international community and I look forward to meeting my colleagues from all over the world.” Jörg P. Kutter, Professor, Technical University of Denmark 7 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Keynote Speaker Series Sponsored by: Monday, February 6, 2012, 9 am Peter G. Schultz, Ph.D. Scripps Family Chair Professor Department of Chemistry, The Scripps Research Institute A Chemist’s Foray Into Translational Medicine Peter G. Schultz and his team are using a variety of cell based screens to identify and characterize the mechanisms of small molecules that affect stem cell self renewal and differentiation, and the reprogramming of somatic cells. During his presentation, examples of this will be discussed including the expansion of cord blood derived HSCs, in vivo neurogenesis, the selective differentiation of MSCs to chondrocytes and osteoblasts, reversible beta cell proliferation, MEF reprogramming, human ESC self renewal and differentiation, and the selective killing of cancer stem cells. Tuesday, February 7, 2012, 9 am Jing Cheng, Ph.D. Member, Chinese Academy of Engineering Director, National Engineering Research Center for Beijing Biochip Technologies CEO, CapitalBio Corporation Cheung Kong Professor, Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing, China Biochips for Translational Medicine CapitalBio, China’s advanced diagnostics powerhouse, has been developing biochip technologies and products for 10 years in collaboration with leading research hospitals in China to satisfy unmet demands from hospital bedsides. The products that have been certified by China SFDA including a DNA microarray analyzing nine mutations in four human genomic and mitochondrial genes account for approximately 80 percent of the causes of inherited deafness, including susceptibility to deafness induced by exposure to aminoglycoside antibiotics, and a protein array for autoimmune disease diagnosis. In addition, two chips that can provide rapid sample-to-answer results in only 6 hours have also been developed, one chip identifies 17 different mycobacteria and the second chip detects the resistance to two first line drugs, Rifampicin and Isoniazid. These two multi-facet TB tests are certified by both the China SFDA and the European Community (CE mark). A number of other close to market products include a HBV drug resistance detection array for Lamivudine and Adefovir and a microfluidic chip for the identification of 12 major bacterialassociated respiratory infections in two hours. Active biochip technologies for fertility and reproductive health will be discussed. A full line of instruments from sample processing to detection of results will also be presented. Wednesday, February 8, 2012, 3:30 pm Robert Ballard, Ph.D. Professor, University of Rhode Island (URI) Graduate School of Oceanography Founder and President, Institute for Exploration (IFE) at Mystic Aquarium, Mystic, Connecticut Deep Sea Science and Exploration Robert Ballard, President of the Institute for Exploration at Mystic Aquarium in Mystic, Connecticut and Director of the Institute for Archaeological Oceanography at the University of Rhode Island’s Graduate School of Oceanography, is best known for his 1985 discovery of the Titanic. Ballard is now using advanced technology to create a new field of research in deep water archaeology. At the Institute for Exploration’s Challenge of the Deep exhibit hall, as well as with his Jason Foundation for Education, Ballard hopes to inspire young people to pursue learning in science, math, and technology through exploration and discovery. This past summer he used satellite and internet technologies to bring thousands of students around the world into direct contact with his team while on location in the Black Sea and Mediterranean Sea. In his talk, through the use of stunning high quality images and personal accounts, Ballard will present his most recent work in deep water archaeology and the technology of tele-presence. He discusses motivating people to think outside the box, learning how to deal with failure — that failure is just a step along the way to success, motivating children to choose careers in math, science and engineering; and how to live your dream. 8 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Conference-at-a-Glance (Schedule Subject to Change) Saturday, February 4, 2012 (Short Course only registration is available.) 8:30 am – 4:30 pm Short Courses: Applied Information Technology for the Laboratory; Automated Liquid Handling in Accredited or Forensic Environments; Automation for In Vitro Diagnostics; Electronic Laboratory Notebooks; Establishing CellBased Assays for Screening; Introduction to Laboratory Automation; LIMS in the Organization; Liquid Handling Boot Camp; Quantitative Evaluation of Screening Assays for Drug Discovery; Sample Management: Best Practice, Trends and Challenges Saturday and Sunday (two-day courses): Getting Started With Excel and VBA in the Laboratory; Microfluidics I/II Sunday, February 5, 2012 (Short Course only registration is available.) 8:00 am – 3:30 pm Short Courses: Automated Assays for Drug Discovery; Automating Scientific Data Analysis and Visualization With Excel and VBA; High Content Screening: Instrumentation, Assay Development, Screening, Image and Data Analysis; Introduction to Design of Experiments; Introduction to Laboratory Automation; Label-Free/Biophysics Methods for Screening; Liquid Handling Boot Camp; Next Generation Sequencing Technologies and Automation Introduction; Pharmacokinetics and Pharmacodynamics in Drug Discovery; Technical Project Management; Writing Testable and Verifiable User Requirements; XML for the Laboratory Saturday and Sunday (two-day courses): Getting Started With Excel and VBA in the Laboratory; Microfluidics I/II 9:00 am – 12:00 pm 8:00 pm Exhibitor Workshops Super Bowl After-Party — Location: JJ's Sponsored by: Monday, February 6, 2012 7:30 – 8:30 am Laboratory Products Association (LPA) Special Session 8:00 – 8:30 am Continental Breakfast 8:30 – 9:00 am Opening Remarks 9:00 – 10:00 am 10:00 am – 6:30 pm Opening Keynote Speaker: Peter G. Schultz, Scripps Family Chair Professor, Department of Chemistry, The Scripps Research Institute Sponsored by: Exhibits Open Track 1: Drug Target Biology Track 2: Assay Development and Screening Track 3: HighThroughput Technologies Track 4: Micro/Nano Technology Bridging the Valley of Death; How Can Academia and Pharma Best Work Together? Evolving HighThroughput Screening Strategies Automated Chemistry and HighThroughput Sample Management Single Cell Analysis and Cytometry Advances in HighThroughput Screening Technologies Nanoprobe Biosensors for Molecular Imaging Track 5: Bioanalytical Techniques Track 6: Diagnostics Advances in Separation and Detection Technologies Laboratory Based Diagnostic Systems – Next Generation Sequencing Advances in Bioanalytical Sample Preparation Methods Portable Point of Care Diagnostic Systems Session 1 10:30 am – 12:30 pm 12:30 – 1:00 pm Lunch Break in Exhibit hall 12:30 – 1:20 pm Exhibitor Tutorials 12:30 – 2:00 pm Exhibitor Tutorials 1:00 – 3:00 pm Poster Session 2:00 – 2:50 pm Exhibitor Tutorials Session 2 3:00 – 5:00 pm New Approaches for Interrogating High Value Drug Targets Screening Library Resources: The Comeback of Natural Products, Fragments & Focused Collections 5:00 – 6:30 pm Reception in Exhibit Hall 7:00 – 9:00 pm Late Night With LRIG-Rapid Fire Innovation Session 8:00 pm Monday Night Diamond Groove-a-Thon — Location: JJ's 9 | SLAS2012.org Sponsored by: Track 7: Informatics Track 7 Begins Tuesday at 3 pm Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Conference-at-a-Glance (Schedule Subject to Change) Tuesday, February 7, 2012 7:00 – 9:00 am Analytical and Life Science Systems Association (ALSSA) Special Session (Invitation Only) 8:00 – 8:30 am Continental Breakfast 8:00 – 8:50 am Exhibtor Tutorials 9:00 – 10:00 am Keynote Speaker: Jing Cheng, Member Chinese Academy of Engineering; Director, National Engineering Research Center for Beijing Biochip Technologies; CEO, CapitalBio Corporation; Cheung Kong professor, Department of Biomedical Engineering, Tsinghua University School of Medicine 10:00 am – 6:00 pm Exhibits Open 10:30 am – 12:30 pm GenomicsBased Drug Discovery Sponsored by: Session 3 Biochemical Assay Technologies in Screening 12:30 – 1:00 pm Lunch Break in Exhibit Hall 12:30 – 1:20 pm Exhibitor Tutorials 12:30 – 2:00 pm Exhibitor Tutorials 1:00 – 3:00 pm Poster Session 2:00 – 2:50 pm Exhibitor Tutorials Physiologically Relevant Screening Systems Droplet Microfluidics Bioanalytical Techniques in Drug Discovery and Development Track 5 Ends Advances in Clinical Diagnostics Track 6 Ends Session 4 3:00 – 5:00 pm 5:00 – 6:00 pm 7:00 – 10:00 pm Understanding the Molecular Mechanisms of Drugs, Promising Natural Products, and Traditional Agents RNAi Screening Technologies HighThroughput Analytics and Automation Session 1 Optofluidics for On-Chip Bioanalysis Data integration Across Multiple Technology Platforms Track 7 Begins Reception in the Exhibit Hall Celebrating JALA and JBS Authors Gaslamp Block Party Bash — Location: Gaslamp Quarter Sponsored by: Wednesday, February 8, 2012 8:30 – 9:00 am Continental Breakfast Session 5 9:00 – 11:00 am 11:00 – 11:30 am Emerging Tools and Approaches for Drug Discovery Cell-Based Assay Technologies in Screening HighThroughput Screening of Biologics Session 2 Tissues and Small Animals On a Chip Informatics Solutions for TerabyteScale Technologies Break 11:00 am – 1:00 pm JALA & JBS Authors Workshop: New Ways to Increase Your Citations 11:30 am – 1:00 pm Lunch 11:30 am – 1:00 pm Special Interest Group Meetings Session 6 1:00 – 3:00 pm 3:00 – 3:30 pm New Life for Old Drugs? Post Screening: Optimizing the Lead and Confirming the Molecular Target Chair’s Choice Session 3 Integrated Microsystems Laboratory Data Discovery: Finding and Using Laboratory Information Break Awards Ceremony and Closing Keynote 3:30 – 5:00 pm Keynote Speaker: Robert Ballard, Professor, University of Rhode Island (URI) Graduate School of Oceanography; Founder and President, Institute for Exploration (IFE) at Mystic Aquarium 10 | SLAS2012.org Sponsored by: Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Accelerate | Conference Schedule (Schedule Subject to Change) Short Course Program is held on Saturday, February 4 and Sunday, February 5. For complete listing, see pages 5–7. Sunday, February 5, 2012 9:00 am – 12:00 pm 8:00 pm Exhibitor Workshops Super Bowl After-Party — Location: JJ's Sponsored by: Monday, February 6, 2012 7:30 – 8:30 am Laboratory Products Association (LPA) Special Session 8:00 – 8:30 am Continental Breakfast 8:30 – 9:00 am Opening Remarks 9:00 – 10:00 am Opening Keynote Speaker: Peter G. Schultz, Scripps Family Chair Professor Department of Chemistry, The Scripps Research Institute Sponsored by: 10:00 am – 6:30 pm Exhibits Open 10:30 am – 12:30 pm Drug Target Biology — Track 1 Bridging the Valley of Death; How Can Academia and Pharma Best Work Together? Chair: Bill Janzen, University of North Carolina; Michelle Palmer, Broad Institute Moderator: Derek Lowe, In the Pipeline Panelists: John Luk, National University of Singapore; Rudy Juliano, University of North Carolina; Mao Mao, Pfizer; Alan D. Palkowitz, Eli Lilly and Company; John Reed, Sanford-Burnham Medical Research Institute 10:30 am – 12:30 pm Assay Development and Screening — Track 2 Evolving High-Throughput Screening Strategies Chair: James Inglese, NIH 10:30 am Screening With Integrating Decision-Making: Maximizing Resources With Continuous Event-Driven HTS of Large Chemical Libraries; Sam Micheal, NIH 11:00 am High-Throughput In Vivo Cellular-Resolution Whole-Animal Screening; Fatih Yanik, Massachusetts Institute of Technology 11:30 am Tissue Dynamics Imaging for Phenotypic Profiling in Drug Screening; David Nolte, Purdue University 12:00 pm Selective Melamine Detection in Multiple Sample Matrices With a Portable Raman Instrument Using SERS-active Gold Nanoparticles; Laura Mecker, US Food and Drug Administration 10:30 am – 12:30 pm High-Throughput Technologies — Track 3 Automated Chemistry and High-Throughput Sample Management Chair: Adam Hill, Novartis 10:30 am DNA Encoded Libraries for Hit Discovery: Some Reflections on the Past Five Years; Barry Morgan, GlaxoSmithKline 11:00 am High-Throughput Sample Management: Enabling Customised HTS; Daniel Baeschlin, Novartis 11:30 am A Novel Platform to Improve HTS Compound Management Operations; Pierre Baillargeon, Scripps Florida 12:00 pm Screening Heuristics & Chemical Property Bias — New Directions for Lead Identification and Optimization; Andy Pope, GlaxoSmithKline 10:30 am – 12:30 pm Micro/Nano Technologies — Track 4 Single Cell Analysis and Cytometry Chair: Dino Di Carlo, University of California, Los Angeles 10:30 am Microfluidic Cytometry for Blood Analysis; Hywel Morgan, University of Southampton 11:00 am Microfluidics 2.0: Cell-Based Discovery and Diagnostics; Cristian Ionescu-Zanetti, Fluxon Biosciences 11:30 am A Flexible New Device and Method to Prepare Cells for Single Cell Analysis; Andre Gross, IMTEK, University of Freiburg 12:00 pm Ligand-Gated Ion Channel: Novel Assay Formats Using a Microfluidic Automated Electrophysiology Platform; Stephen Smith, Fluxion Biosciences 10:30 am – 12:30 pm Bioanalytical Techniques — Track 5 Advances in Separation and Detection Technologies Chair: Carlos Garcia, University of Texas, San Antonio 10:30 am Chemical Laptop Platform for Environmental Monitoring Applications; Hong Jiao, HJ Science and Technology Inc. 11:00 am Technology Trends in Mobile Water Analysis; Juan Gonzalez, Hach Inc. 11:30 am Increased Functionality in Protein Purification Systems; Craig Schulz, Amgen, Inc. 12:00 pm New Dielectrophoretic (DEP) Devices for Automated Sample to Answer Diagnostics and Bioanalysis; Michael Heller, University of California, San Diego 11 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Conference Schedule 10:30 am – 12:30 pm Diagnostics — Track 6 Laboratory Based Diagnostic Systems — Next Generation Sequencing Chair: Gregory Heath, Illumina, Inc. 10:30 am Clinical Applications of Next Generation Sequencing; Gregory Heath, Illumina, Inc. 11:00 am Genomics Medicine: Recent Progresses and Future Challenges; Mostafa Ronaghi, Illumina, Inc. 11:30 am Automated Liquid Handling for Next Generation Sequencing Sample Preparation Applications; Andrew Barry, Caliper Life Sciences 12:00 pm Increasing Throughput of DNA Library Preparation to Meet Emerging Needs of Next Generation Sequencing; Vibhu Vivek, Microsonic Systems Inc. 12:30 – 1:00 pm Lunch Break in Exhibit Hall 12:30 – 1:20 pm Exhibitor Tutorials 12:30 – 2:00 pm Exhibitor Tutorials 1:00 – 3:00 pm Poster Session 2:00 – 2:50 pm Exhibitor Tutorials 3:00 – 5:00 pm Drug Target Biology — Track 1 New Approaches for Interrogating High Value Drug Targets Chair: Haian Fu, Emory University 3:00 pm Changing Landscape of Drug Targets; Haian Fu, Emory University 3:30 pm Crystal Structure of the Ectodomain Complex of the CGRP Receptor: Insights Into Drug Antagonism of a Class B GPCR; Jonathan Moore, Vertex Pharmaceuticals 4:00 pm Proteases as Drug Targets — A Difficult Target Class With Accelerated Success and Still Many More Opportunities; Lorenz Mayr, Novartis 4:30 pm Therapeutic Targeting of Mcl-1 Protein-Protein Interactions in Human Cancers; Zaneta Nikolovska-Coleska, University of Michigan 3:00 – 5:00 pm Assay Development and Screening — Track 2 Screening Library Resources: The Comeback of Natural Products, Fragments & Focused Collections Chair: Ron Quinn, Eskitis Institute, Griffith University 3:00 pm Natural Products and Close Relatives as Sources of Drug Leads; David Newmann, NCI 3:30 pm Optimized Methods for Screening and Analysis of Stereochemically Diverse Libraries; Joshua Bittker, Broad Institute of Harvard and MIT 4:00 pm Modern Methods for Rapid Development of Robust Small-Molecule SPR Assays: A Variety of Lessons Learned From Difficult Proteins in Different Target Classes; Anthony Gianetti, Genentech 4:30 pm Lessons From Global Consideration of Natural Products: Can Natural Products be Used in Fragment-Based Screening?; Ron Quinn, Eskitis Institute, Griffith University 3:00 – 5:00 pm High-Throughput Technologies — Track 3 Advances in High-Throughput Screening Technologies Chair: Wayne Bocchinfuso, Eli Lilly and Company 3:00 pm Moving HCS into HTS...The Journey of Moving From 384 to 1536-Well Automated High Content Assays; Debra Nickischer, Bristol-Myers Squibb Company 3:30 pm High Content Mass Cytometry Screening to Study Single Cell Signaling Networks in Biology and Disease; Bernd Bodenmiller, Stanford University School of Medicine 4:00 pm Two High Content Screening Approaches for the Rare Neurological Disease Amyotrophic Lateral Sclerosis; Marcie Glicksman, Brigham and Women 4:30 pm Can Peptide Substrates Properly Represent Physiological Substrates in Drug Discovery; Min Liu, LDDN 3:00 – 5:00 pm Micro/Nano Technologies — Track 4 Nanoprobe Biosensors for Molecular Imaging Chair: Yingxiao (Peter) Wang, University of Illinois at Urbana-Champaign 3:00 pm Fluorogenic and FRET-Based Nanoprobes for Live Cell Imaging; Gang Bao, Georgia Tech University 3:30 pm Molecular Imaging in Live Cells for Studying Cell-Environment and Cell-Cell Interactions; Yingxiao (Peter) Wang, University of Illinois at Urbana-Champaign 4:00 pm Non-Optical Detection Technology for the Rapid and Sensitive Detection and Quantitation of Proteins in Complex Biological Matrices; Brian Lightbody, BioScale 4:30 pm Use of High-Throughput Cell-Based and Model Organism Assays for Understanding the Potential Toxicity of Engineered Nanomaterials; Keith Houck, US EPA 12 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Conference Schedule 3:00 – 5:00 pm Bioanalytical Techniques — Track 5 Advances in Bioanalytical Sample Preparation Methods Chair: Thomas Perroud, Illumina, Inc. 3:00 pm Mutation-Specific Sequence Enrichment Using SCODA; Andre Marziali, Boreal Genomics 3:30 pm RNA Sample Preparation for Next Generation Sequencing; Shujun Luo, Illumina, Inc. 4:00 pm Automated Quality Control Platform for Next-Generation Sequencing Library Preparation; Numrin Thaitrong, Sandia National Laboratories 4:30 pm One-Step Analyte Isolation; David Beebe, University of Wisconsin 3:00 – 5:00 pm Diagnostics — Track 6 Portable Point of Care Diagnostic Systems Chair: Greg Sommer, Sandia National Laboratories 3:00 pm The Programmable Bio-Nano-Chip: A Fully Automated Platform That Bridges From Biomarker Discovery to Clinical Application; John McDevitt, Rice University 3:30 pm A Fully Integrated Microfluidic Instrument for Automated On-Cartridge Biodosimetry; Matthew Estes, Center for Applied NanoBioscience and Medicine, University of Arizona 4:00 pm Towards True Miniaturization of Raman Instrumentation for Bioanalytical and Clinical Applications: Challenges and Possible Solutions; Narahara Chari Dingari, Massachusetts Institute of Technology 4:30 pm POC Industry Overview: What Can We Learn From the High Tech Industry; Amit Agarwal, Scientia Advisors 5:00 – 6:30 pm Reception in Exhibit Hall 7:00 – 9:00 pm Late Night With LRIG-Rapid Fire Innovation Session 8:00 pm Monday Night Diamond Groove-a-Thon — Location: JJ's Sponsored by: Tuesday, February 7, 2012 7:00 – 9:00 am Analytical and Life Science Systems Association (ALSSA) Special Session (Invitation Only) 8:00 – 8:30 am Continental Breakfast 8:00 – 8:50 am Exhibtor Tutorials 9:00 – 10:00 am 10:00 am – 6:00 pm 10:30 am – 12:30 pm Plenary Session Chair: Keynote Speaker: Jing Cheng, Member Chinese Academy of Engineering; Director, National Engineering Research Center for Beijing Biochip Technologies; CEO, CapitalBio Corporation; Cheung Kong professor, Department of Biomedical Engineering, Tsinghua University School of Medicine Sponsored by: Exhibits Open Drug Target Biology — Track 1 Genomics-Based Drug Discovery Chair: Jonathan Derry, SageBionetworks 10:30 am A Porous Needle Array Technology Platform for Multiplexed In Vivo Oncology Target Validation Studies; Richarg Klinghoffer, Presage 11:00 am Functional Genomics to Identify Cancer Targets; Jesee Boehm, Broad Institute 11:30 am Next-Generation Sequencing as a Means to Discover and Develop Novel Cancer Biomarkers; Mao Mao, Pfizer 12:00 pm Targeting Nad Biogenesis: A Path Toward Irresistible Antibiotics; Andrei Osterman, Sanford Burnham Medical Research Institute 10:30 am – 12:30 pm Assay Development and Screening — Track 2 Biochemical Assay Technologies in Screening Chair: Andrew Napper, Nemours Center for Childhood Cancer Research 10:30 am Label-Free Tools in Early Discovery: Compound Mode of Action Gleaned From Orthogonal Profiling of HTS Positives; Matthew Todd, Johnson & Johnson 11:00 am Innovative Assay Design for Protein-Protein Interaction Modulator Discovery; Yuhong Du, Emory University 11:30 am Real-Time Measurement of Protein Conformational Change in Key Therapeutic Targets: Application to Abl Kinase and Mutant Ras; Joshua Salafsky, Biodesy LLC 12:00 pm From Biological Phenomenon to Practical Drug Discovery: Development of Physiologically-Relevant Screening Assays in the Novel Target Space of Epigeneic Enzymes; Margaret Porter Scott, Epizyme 13 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Conference Schedule 10:30 am – 12:30 pm High-Throughput Technologies — Track 3 Physiologically Relevant Screening Systems Chair: Jonathan Lee, Eli Lilly and Company 10:30 am Automated, In Vivo Screening for Behavior-Modifying Compounds; Randall Peterson, Cardiovascular Research Center Mass General Hospital 11:00 am A High Definition Screening Technology for Stem Cell Modulators; Sheng Ding, University of California, San Francisco 11:30 am Potent Inhibitors of Lipid Droplet Accumulation in Liver and Muscle Identified From the NIH Molecular Libraries Collection; Siobhan Malany, Sanford Burnham Medical Research Institute 12:00 pm Patient Specific Cell Based Disease Models for Drug Discovery; Anne Bang, Conrad Prebys Center for Chemical Genomics 10:30 am – 12:30 pm Micro/Nano Technologies — Track 4 Droplet Microfluidics Chair: Cory Gerdts, Emerald Biosystems 10:30 am Microfluidic Droplets, Vesicles, and Bubbles: From Digital Biology to Targeted Therapy; Abe Lee, University of California, Irvine 11:00 am SlipChip High-Throughput Platform for Protein Crystallization and Molecular Diagnostics; Liang Li, SlipChip 11:30 am Partipetting & Spinning Color Barcoded Microparticles for Ultraplex Bio-Assay; Sunghoon Kwon, School of Electrical Engineering, Seoul National University 12:00 pm Digital Microfluidics for Automated Library Preparation of Next Generation Sequencing; Hanyoup Kim, Sandia National Laboratories 10:30 am – 12:30 pm Bioanalytical Techniques — Track 5 (Track 5 Ends) Bioanalytical Techniques in Drug Discovery and Development Chair: Chris Morrow, Genentech 10:30 am An Intercalated Software & Hardware Based Genotyping Pipeline; Colin Cox, Genentech 11:00 am A Role for Large Molecule Bioanalytical Automation in a Discovery/Early Development Setting; Sheldon Leung, Pfizer 11:30 am Nanomaterials, Proteins, and the Solution in Between Them; Carlos Garcia, University of Texas, San Antonio 12:00 pm High-Throughput Sample Dilution in a GXP Environment; Chris Morrow, Genentech 10:30 am – 12:30 pm Diagnostics — Track 6 (Track 6 Ends) Advances in Clinical Diagnostics Chair: Kevin Halling, Mayo Clinic 10:30 am Development and Validation of Genetic Biomarkers for Oncology; Kevin Halling, Mayo Clinic 11:00 am Development and Validation of Protein Based Biomarkers; Samir Hanash, Fred Hutchinson Cancer Research Center 11:30 am Applying Metabolomics to Neglected Tropical Disease Diagnostics; Tobin Dickerson, The Scripps Research Institute 12:00 pm An AC Electrokinetic Device for the Separation and Detection of Cancer Related Nanosomes; Krishnan Rajaram, Biological Dynamics, Inc. 12:30 – 1:00 pm Lunch Break in Exhibit Hall 12:30 – 1:20 pm Exhibitor Tutorials 12:30 – 2:00 pm Exhibitor Tutorials 1:00 – 3:00 pm Poster Session 2:00 – 2:50 pm Exhibitor Tutorials 3:00 – 5:00 pm Drug Target Biology — Track 1 Understanding the Molecular Mechanisms of Drugs, Promising Natural Products, and Traditional Agents Chair: Lixin Zhang, Institute of Microbiology, Chinese Academy of Sciences, Beijing 3:00 pm Increasing Natural Product Libraries for Drug Discovery; John Clardy, Harvard Medical School 3:30 pm Bioprospecting Natural Products for Potential Anti Infective Drug; Lixing Zhang, Institute of Microbiology, Chinese Academy of Sciences, Beijing 4:00 pm Dynamic Biomarkers of Triglyceride and Cholesterol Metabolism for Application in Drug Discovery; Thomas Roddy, Merck 4:30 pm Identification of Uncompetitive Inhibitors of Caspase-6: A Mechanistic and Structural Understanding; Christopher Heise, Genentech 14 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Conference Schedule 3:00 – 5:00 pm Assay Development and Screening — Track 2 RNAi Screening Technologies Chair: Susan Magdaleno, Life Technologies, USA 3:00 pm Silencer ® Select siRNA: Combining Novel siRNA Design and LNA® Chemical Modification for Enhanced Specificity Without Compromising Performance; Susan Magdaleno, Life Technologies, USA 3:30 pm Lentivirus Enabled shRNA Drug Modifier Screens: Panoramic View of the Human Genome One Hairpin at a Time; Hakim Djaballah, MSKCC 4:00 pm siRNA Screening to Identify Novel Modulators of Aβ Homeostasis; Paul Kassner, Amgen, Inc. 4:30 pm Viability Screens in Leukemic and Breast Cancer Cells With Pooled Lentiviral shRNA Libraries Identify Potential Therapeutic Targets and Synergistic Lethal Interactions; Alex Chenchik, Cellecta, Inc. 3:00 – 5:00 pm High-Throughput Technologies — Track 3 High-Throughput Analytics and Automation Chair: Matt Greving, Nextval 3:00 pm Large Scale Gene Expression Analysis of Cellular States; Arvind Subramanian, Broad Institute 3:30 pm Activity-Based Proteomics for Quantitative Profiling of Enzyme Function; Chu Wang, Scripps 4:00 pm Accelerating Drug Discovery: Automation, Robotics, Remote Access and High-Throughput Technologies at the SSRL Protein Crystallography Beam Lines; Clyde Smith, Stanford University 4:30 pm Flexible HCS Automation — Sharing Cellular Imaging Capability Across the Oncology Drug Discovery Cascade; Roger Clark, AstraZeneca Pharmaceuticals 3:00 – 5:00 pm Micro/Nano Technologies — Track 4 Optofluidics for On-Chip Bioanalysis Chair: Holger Schmidt, University of California, Santa Cruz 3:00 pm OptoFluidic Detection System Enabling Sophisticated Point-of-Care Diagnostics; Peter Kiesel, PARC 3:30 pm Optofluidic Waveguide Development for High Sensitivity Bioparticle Detection; Aaron Hawkins, Brigham Young University 4:00 pm Surface Enhanced Raman Scattering (SERS) Cytometry for Multiparameter Cell Analysis; John Nolan, La Jolla Bioengineering Institute 4:30 pm Tuning Energy Transfer and Spectral Selectivity in Lanthanide-Doped Upconverting Nanoparticles With High-Throughput Screening; Emory Chan, Lawrence Berkeley National Laboratory 3:00 – 5:00 pm Informatics — Track 7 (Track 7 Begins) Data Integration Across Multiple Technology Platforms Chair: William Goode, Amgen, Inc. 3:00 pm Facilitating Target Candidate Prioritization Via Integrated, Interactive Visualizations of Molecular Profiling Data; Wolfgang Hoeck, Amgen, Inc. 3:30 pm Material Master: Federation Across Multiple Biologics Repositories; David Dorsett, Bristol-Myers Squibb Company 4:00 pm Data Quality Assessment Enables Knowledge Management; Bob O’Hara, ResultWorks, LLC 4:30 pm Unison: An Integrated Platform for Computational Drug Target Discovery; Kiran Mukhyala, Genentech 5:00 – 6:00 pm 7:00 – 10:00 pm Reception in the Exhibit Hall Celebrating JALA and JBS Authors Gaslamp Block Party Bash — Location: Gaslamp Quarter Sponsored by: Wednesday, February 8, 2012 8:30 – 9:00 am 9:00 – 11:00 am Continental Breakfast Drug Target Biology — Track 1 Emerging Tools and Approaches for Drug Discovery Chair: Dan Shoemaker, Fate Therapeutics 9:00 am RASL-seq: A Deep Sequencing-Based Platform for Chemical Screenings; Xiang-Dong Fu, University of California, San Diego 9:30 am Mark Chee, Prognosys Biosciences 10:00 am A Pharmacoempiric Platform for Personalized Cardiovascular Drug Discovery; Will Adams, Harvard Medical School 10:30 am Miniaturization and Optimization of FAIRE to Increase Throughput and Efficiency; Chatura Jayakody, University of North Carolina 15 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Conference Schedule 9:00 – 11:00 am Assay Development and Screening — Track 2 Cell-Based Assay Technologies in Screening Chair: Thierry Dorval, Institute Pasteur Korea 9:00 am A Biosensor Based High Content Screen for Modulators of the EGF Receptor: Merits of Live Cell Based Assays?; Christopher Antczak, MSKCC 9:30 am Multiplex Transduction Based on Encoded Micropatch Immobilizing Viral Vector for High-Content Screening Assay; Park Wook, Seoul National University 10:00 am Leverage Innovation in High Content Screening — Integration of Bioimaging, Informatics and Data Management to Realize High-Throughput High Content Screening Using Physiologically Relevant Cellular Models; Julie Li, Sanofi-Aventis 10:30 am Human Induced Pluripotent Stem Cell Derived Cardiomyocytes; Multi-Platform Screening for Ion Channel Function and Pharmacology; Blake Anson, Cellular Dynamics International 9:00 am – 11:00 am High-Throughput Technologies — Track 3 High-Throughput Screening of Biologics Chair: Jean-Phillipe Stephan, Genentech 9:00 am High-Throughput Cellular Assays Using a “Well-Less” Plate Format; Gabriel Quinones, Genentech 9:30 am High-Throughput Biochemical Assays for Screening Antibody Clones; Pamela Chan, Genentech 10:00 am High-Throughput In Vitro Biochemical Synthesis of Non-Natural Amino Acid Biotherapeutic Proteins; Remesh Baliga, Sutro Biopharma 10:30 am Development and Application of Automated Systems for Plasmid-Based Functional Proteomics to Improve Syntheitc Biology of Engineered Industrial Microbes; Stephen Hughes, USDA, NCAUR, ARS, BBC 9:00 am – 11:00 am Micro/Nano Technologies — Track 4 Tissues and Small Animals on a Chip Chair: Fatih Yanik, Massachusetts Institute of Technology 9:00 am High-Throughput Vertebrate Imaging, Surgery, and Screening at Cellular Resolution; Fatih Yanik, Massachusetts Institute of Technology 9:30 am Zebrafish in Drug Discovery: An Industry Perspective; Andrew Dodd, Evotech 10:00 am A Digital Microfluidic Method for Parallel-Scale Cell-Based Apoptosis Assays; Dario Bogojevic, University of Toronto 10:30 am A Human Breathing Lung-on-a-Chip for Drug Screening and Nanotoxicology Applications; Dan Dongeun Huh, Harvard University 9:00 am – 11:00 am Informatics — Track 7 Informatics Solutions for Terabyte-Scale Technologies Chair: Chris Dagdigian, BioTeam 9:00 am Where Did I Put That Again? Case Studies in Managing Unstructured Data With iRODS; Chris Smith, Distributed Bio 9:30 am Software Design and Architecture for the New Genomic Era; Mick Correll, Dana-Farber Cancer Institute 10:00 am CellOrganizer: Image-Derived Models of Subcellular Organization Over Time and Space; Robert Murphy, Carnegie Mellon University 10:30 am Development of High-Throughput Laboratory and Analysis Workflows for Whole Exome Capture, Sequencing and Analysis; Olivier Harismendy, University of California, San Diego 11:00 – 11:30 am Break 11:00 am - 1:00 pm JALA & JBS Authors Workshop: New Ways to Increase Your Citations 11:30 am – 1:00 pm Lunch 11:30 am – 1:00 pm Special Interest Group Meetings 1:00 – 3:00 pm Drug Target Biology — Track 1 New Life for Old Drugs? Chair: Justin Lamb, Broad Institute 1:00 pm New Uses for Old Drugs: Data and Chemistry Challenges; Chris Lipinski, Melior Discovery 1:30 pm Pinging the Transcriptome; Mining System Wide Transcriptional Databases for Rare Inherited Disorder Therapeutic Leads; Alex MacKenzie, Children's Hospital of Eastern Ontario 2:00 pm An Ex-Vivo Drug Sensitivity Profiling Platform of Adult AML Identifies Patient-Specific Novel Molecular Drivers of Adult and Novel Therapeutic Combinations; Krister Wennerberg, Institute for Molecular Medicine Finland, FIMM 2:30 pm Identification of New Molecular Targets Among Known Drugs; Wesley Kroeze, University of North Carolina 16 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Conference Schedule 1:00 – 3:00 pm Assay Development and Screening — Track 2 Post Screening: Optimizing the Lead and Confirming the Molecular Target Chair: Tim Hammonds, Wolfson Institute for Biomedical Research 1:00 pm Cell Based Screening for Regulators of p53 Dependent Transcription; David Lane, Singapore 1:30 pm Molecular Tools for Target Identification From ‘Black-Box’ Cell Based Screens. What Can Medicinal Chemistry Bring to the Tool Box?; John Roffey, Cancer Research UK 2:00 pm Identification of Physiologically Relevant Modulators for Human Tissue Non-Specific Alkaline Phosphatase; Eduard Sergienko, Sanford Burnham 2:30 pm Novel Cell-Based Assay for Characterizing Fatty Acid Metabolism; Lawrence Wiater, Biolog 1:00 – 3:00 pm High-Throughput Technologies — Track 3 Chair’s Choice Chair: Tim Dawes, Genentech 1:00 pm Improving Phenotypic Assay Analyte Detection Using Proximity Ligation Assay (PLA) Methodology; Steven Ludbrook, GlaxoSmithKline 1:30 pm Multiplex Quantification of mRNAs With Barcoded Hydrogel Microparticles; Nakwon Choi, Novartis 2:00 pm Controlling Stem Cell Growth and Differentiation by Automation: Enhanced and More Reliable Differentiation for Drug Discovery; Michael Kowalski, Beckman Coulter 2:30 pm Modern Phenotypic Drug Discovery is a Viable Pharma Strategy; Jonathan Lee, Eli Lilly and Company 1:00 – 3:00 pm Micro/Nano Technologies — Track 4 Integrated Microsystems Chair: Kamlesh Patel, Sandia National Laboratories 1:00 pm Ultra-High Throughput On-Chip Microscopy and Cytometry Using Lensfree Computational Imaging; Aydogan Ozcan, University of California, Los Angeles 1:30 pm Electrokinetic Microfluidics and Biomedical Lab-on-a-Chip Devices; Dongqinq Li, University of Waterloo 2:00 pm An Integrated Miniaturized Platform for High-Throughput RNAi Screens Using Microfabrication and Nanoliter Scale Dispensing; Tilak Jain, Scripps 2:30 pm New Platform Technology for Simple, Consistent Production of Collagen Based Tissues for Physiologically Relevant Assays; Rosemary Drake, TAP Biosystems 1:00 – 3:00 pm Informatics — Track 7 Laboratory Data Discovery: Finding and Using Laboratory Information Chair: James Gill, Bristol-Myers Squibb Company 1:00 pm Automating Biology Using Robot Scientists; Ross King, Aberystwyth University 1:30 pm Complex Data Management - Lessons From Recipes or What Do I Want For Dinner?; Alden Hart, Ten Mile Square 2:00 pm Cloud-Based Collaboration and Long-Term Archiving Using the AnIML Standard; Burkhard Schaefer, BSSN Software 2:30 pm Active Learning Methods for High Dimensional Perturbagen-Target Spaces; Armaghan Naik, Carnegie Mellon University 3:00 – 3:30 pm Break 3:30 – 5:00 pm Awards Ceremony and Closing Keynote Keynote Speaker: Robert Ballard, Professor, University of Rhode Island (URI) Graduate School of Oceanography; Founder and President, Institute for Exploration (IFE) at Mystic Aquarium Sponsored by: SLAS Video Channel Be sure to watch the wacky, irreverent SLAS2012 video on YouTube by going to the SLAS Video Channel. 17 | SLAS2012.org Strategic Alliances Bring Special Sessions to SLAS2012 Laboratory Products Association (LPA), Monday, February 6, 7:30 – 8:30 am LPA and SLAS host a special session to announce the preliminary results of the 2012 North American Laboratory Equipment Purchasing Trends Study. The study addresses emerging trends such as: spending for laboratory products broken down by categories; capital and non-capital equipment budgets; building of new laboratories; personnel issues to include the number of people in the laboratory, hiring, and work load changes; use of social media in the laboratory; and more. K.C. Warawa of K.C. Associates who conducted the joint survey, will present the findings and compare the results to previous studies. Late Night With LRIG-Rapid Fire Innovation, Monday, February 6, 7 – 9 pm A highly interactive forum which weaves together all the constituent audiences participating at SLAS2012 to discuss and learn about the latest innovations in technology products and services impacting laboratory automation and screenin g. Participants will enjoy quick information-bites from approximately 15 companies and a fertile ground for questions-and-answers in an open-space atmosphere. Complimentary refreshments are served. Seating is limited and on a first-come, first-served basis. Admission is FREE. Analytical and Life Science Systems Association (ALSSA), Tuesday, February 7, 7 – 9 am This exclusive invitation-only breakfast provides an informal forum for dialogue among the senior executive of ALSSA members attending SLAS2012 and features presentations from leading academics and users on global trends in laboratory automation technologies and applications and the strategic implications. E-mail [email protected] with ideas and feedback. Interested in sponsorship advertising? Contact Mary Michalik at [email protected]. Short Courses: February 4–5 Conference: February 6–8 Celebrate Innovation Tony B. Academic Travel Awards The Tony B. Academic Travel Awards recognizes approximately 50 up-and-coming researchers who have demonstrated outstanding achievement in laboratory science and technology. The Tony B. Academic Travel Awards include roundtrip coach airfare or mileage reimbursement, conference registration and shared accommodations. $10,000 SLAS Innovation Award The SLAS Innovation Award recognizes the most unique and innovative scientific podium presentation at SLAS2012. Young Scientist Awards Program Recognizes Best Student Poster Presentations From Around the World This program rewards achievement in student poster presentations from strategically aligned sister organizations, institutions and educational forums including the American Institute of Chemical Engineers, Institute of Food Technologists and European Laboratory Robotics Interest Group. Recipients of the Young Scientist Awards are part of the Academic Travel Awards program. Be sure to come and listen to the presentations from these emerging scientists who are actively engaged in laboratory science and technology research. Student Poster Competition SLAS selects the top student posters from around the world to be presented at SLAS2012. Student posters automatically qualify for the SLAS Student Poster Competition, which offers a $750 for first place, $500 for second place and $250 for third place. The award-winning posters will be featured in an issue of JALA and/or JBS following the conference and identified as winners on LabAutopedia. SLAS Journal Awards of Excellence SLAS's two peer-reviewed scientific journals, the Journal of Biomolecular Screening (JBS) and the Journal of Laboratory Automation (JALA) both honor and celebrate the best of 2010 with Readers' Choice Awards, Authors' Choice Awards and Reviewer Excellence Awards. Sidebar Photos From Top to Bottom: Kamlesh Patel, Department Manager for the Advance Systems Engineering and Deployment Group; Preparation of Nucleic Acid Libraries for Ultra High Throughput Sequencing with a Digital Microfluidic Hub, is the $10,000 Innovation Award Winner. 1st Place Student Poster: Human Tear Fluid-Based Point-of-Care Diagnostics Enabled by Integrated Microfluidic Systems; Kelly Karns, University of California, Berkeley, presented at SBS2011. 1st Place Student Poster: Microfluidic Platform for High-Throughput Drug Screening of Angiogenesis Inhibitors During Endothelial Vessel Formation; Travis Moore, Ju Hun Yeon, Sudong Kim, Hyun Jae Lee and Noo Li Jeon, Seoul National University, School of Mechanical and Aerospace Engineering, presented at LabAutomation2011. 19 | SLAS2012.org Exhibition: February 6–7 SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org SLAS2012@Night Offers Good Times and Great Networking with the SLAS Community Celebrate! Sunday thru Wednesday, February 5–8 | Discounts & Drink Specials at JJ's After hours at SLAS2012, kick back and relax or see and be seen at JJ's Restaurant — a legendary and lively anchor of the Gaslamp Quarter that's just a short walk from the convention center and Marriott and Hilton hotels. JJ's is the SLAS2012 "corner bar" where SLAS2012 participants can enjoy exclusive discounts and drink specials all week long. It's the place to go for pool, ping pong, plasma TVs and even dancing. This 15,000 square foot historic brick warehouse will welcome SLAS2012, participants with indoor and outdoor beverage bars, plus lunch, dinner and late-night pub fare (burgers, tacos, salads, steaks). JJ's is open until 1:30 am daily. SLAS2012@Night Sponsors: SLAS2012 features three premier special events to light up the nights: Sunday, February 5, 8 pm Super Bowl After-Party Sponsored by LRIG San Diego and LRIG Bay Area, this celebratory Super Bowl After-Party takes place at JJ's and is open to all SLAS2012 participants. Register to attend on either of the LRIG websites, guess the correct winning score of the big game, and you could win a Kindle Fire or a number of gift cards being given away. Special SLAS discounts on food and beverages ensure this will be a great way to kick off the start of SLAS2012. Monday, February 6, 8 pm Monday Night Diamond Groove-a-Thon Diamond Sponsor PerkinElmer's world famous rock band, "Molecular Groove," is live and loud at JJ's on Monday night so join the rest of the SLAS2012 contingency for a rockin' good time. Renowned on the tour as the "hardest working band in science," Molecular Groove is sure to blow the roof off of JJ's. Stop by, take a load off, and let the good times roll. Special SLAS discounts on food and beverages apply. Tuesday, February 7, 7-10 pm Gaslamp Block Party Bash Don't miss the Gaslamp Block Party Bash, generously hosted by Premier Sponsor Agilent Technologies. SLAS2012 participants will storm the streets of the Gaslamp Quarter in the heart of downtown San Diego. Twist n' shout along with American English — the "Best Tribute Band" for four years running — as they fill the San Diego night with the best of the Beatles. Come hungry and graze the outdoor buffets and open bars. Play ping pong and foosball in the fresh air or simply sit and enjoy the comfortable lounge seating that lines the streets. Expect lots of fun at this first-of-its-kind big bash event! 20 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Investigate | A Robust and Lively Exhibition SLAS2012 plays host to a robust exhibition exploring more than 500+ exhibit booths showcasing over 275 of the most innovative companies from around the world. It’s where new innovation is unveiled, energy runs high and collaborations begin. Visit SLAS2012.org Exhibitor Workshops and Tutorials — Learn About the Science Behind the Technology As part of the technical program, exhibiting companies will present FREE scientific workshops and tutorials. Each of these is designed to give you an in-depth look at topics of ongoing practical interest. Exhibitor Workshops as of October 21: ºº Molecular Devices ºº PerkinElmer Tutorial Companies as of October 21: ºº ºº ºº ºº Bio Rad Laboratories BioTek Instruments Inc. Cell Signaling Technology Cellular Dynamics ºº ºº ºº ºº ForteBio Genedata Labcyte Molecular Devices LLC ºº ºº ºº ºº PerkinElmer Promega Siloam Biosciences Thermo Scientific Visit SLAS2012.org/program/exhibitorworkshops.cfm for descriptions and new listings. The Entrepreneurial Spirit Shines on Innovation AveNEW Interact and engage with some of the newest and most creative products and services in the laboratory science and technology field. Visit Innovation AveNEW, where a select group of emerging companies from around the world have been chosen to participate. Past participants include start-ups from Singapore, Korea, Germany, the United Kingdom, and Switzerland to name a few. New Product Award Recognizes the Best of What’s New SLAS2012 is the ideal venue for companies to launch new products. The prestigious SLAS New Product Award (NPA) designation recognizes and rewards up to three of the newest and most innovative automation and technology products for research and discovery in the laboratory. Past winners include: LabAutomation2011 ºº ºº ºº Cellasic — Pearl Microfluidic Hepatocyte Culture System Covaris, Inc. — LE220 Ultrasonicator Microsaic Systems Ltd — Microsaic 3500 MiD SBS 2011 ºº ºº ºº InSphero: GravityPLUS System Pharmadiagnostics: SoPRano Surface Plasmon Resonance (SPR) -Based Screening using a Standard Absorbance Plate Reader Teflabs: Asante NaTRIUM Green and Asante Potassium Green Ion Channel Dyes The Ultimate Online Product Directory The Market Place for Laboratory Science and Technology is the ultimate online product directory with quick-andeasy access to an ever-expanding collection of new and existing technology products and services for your laboratory. To explore the latest products and services, visit SLAS.org/marketplace/index.cfm 21 | SLAS2012.org SL AS 2012 pla ys ho st to severa l of the FIR ST Ro bo tic s Co mp eti tio n Tea ms as they dis pla y and op era te the ir win nin g rob ots in the SL AS Me mb er Ce nte r. Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Exhibitor List (as of October 14, 2011) 4titude Ltd AAT Bioquest, Inc. Accel Biotech, Inc. Advanced Chemistry Development, Inc., (ACD/LABS) Agilent Technologies Inc. Akonni Biosystems AllMotion Almac Sciences Alpaqua Engineering LLC Amnis Corporation Analytical Biological Services, Inc. (ABS) Angelantoni Industrie SpA Applied Innovation Group Apricot Designs Arise Biotech Corporation Art Robbins Instruments ARTEL AssayMetrics Limited ASI / Applied Scientific Instrumentation Inc. Atlantic Lab Equipment LLC Aurora Biomed, Inc. Axxam SpA Bal Seal Engineering, Inc. BD Biosciences Beckman Coulter, Inc. BellBrook Labs BERTHOLD TECHNOLOGIES GmbH & Co. KG Bigneat Containment Technology Bio Chromato Co., Ltd. Bio-Rad Laboratories Biodirect Inc. BioFluidix GmbH BioFocus Biohit, Inc. Biolog BioMedTech Laboratories, Inc. BioMicroLab, Inc. BioNex Solutions, Inc. BioScale, Inc. BioSero BioTek Instruments, Inc. Biotix, Inc. Blue Sky Biotech, Inc. bluechiip Ltd BMG Labtech, Inc. Bosch Rexroth Corporation BPS Bioscience Inc. Brady Corporation BrandTech Scientific, Inc. BSSN Software Burkert Fluid Control Systems Cadence, Inc. Caliper Life Sciences, Inc. CapitalBio Corporation Cayman Chemical Company CCS Cell Culture Service, Inc. Cell Signaling Technology Cellecta, Inc. Cellular Dynamics IT ChanTest Corporation Chemglass Life Sciences Chieftek Precision Co., Ltd. CiDRA Precision Services, LLC Cisbio Bioassays Clippard Instrument Lab., Inc. Computype, Inc. Conductive Technologies Inc. Core Informatics Corning Life Sciences Covaris, Inc. / KBioscience CSEM SA Curiox Biosystems CyBio AG Cynvenio Biosystems, Inc. Cyth Systems, Inc. Data Unlimited International, Inc. Diba Industries Inc. Douglas Scientific Drug Discovery News Dynamic Devices E&K Scientific Products Inc. Elmo Motion Control, Inc. EMD Millipore Enamine Eppendorf North America EPSON Robots Essen BioScience Etaluma, Inc. Excel Scientific, Inc. Falcon Electric Festo Corporation FlexLink Systems, Inc. FluidX Fluxion Biosciences Formulatrix, Inc. ForteBio, Inc. Freezerworks, a Division of Dataworks Development, Inc. Frontier Scientific Services Gems Medical Sciences Genedata AG Gilson, Inc. Global FIA GNF Systems Greiner Bio-One Hamamatsu Corporation Hamilton Company Harmonic Drive LLC HEIDENHAIN Corporation Hettich Centrifuges HighRes Biosolutions, Inc. HIWIN Corporation Hudson Robotics, Inc. IDBS IDEX Health & Science Igus, Inc. IKO International, Inc. ILS ImageXpert Inc. IMS Schneider Electric Motion IMTEK – Department of Microsystems Engineering INDIGO Biosciences Inc. infoteam Software AG INHECO Industrial Heating & Cooling GmbH Innoprot Innovate Engineering & Design, Inc. Integra / Viaflo IntelliCyt Corporation Invetech, Inc. IonField Systems LLC J-Kem Scientific Kawator KBiosystems Ltd Kloehn / Norgren KNF Neuberger Inc. Lab Services B.V. Labcon North America Labcyte, Inc. Labman Automation Ltd LabSmith, Inc. Labtronics Inc. LabVantage Solutions, Inc. LabWare, Inc. Lathrop Engineering Inc. LEAP Technologies The Lee Company LiCONiC US, Inc. Life Chemicals, Inc. Lin Engineering, Inc. Lonza Lorring & Associates / Gotmotion LLC Macherey-Nagel, Inc. matrical bioscience MaxCyte, Inc. MéCour Temperature Control Mettler Toledo microfluidic ChipShop GmbH MicroLiter Analytical Supplies, Inc. Micronic North America, LLC Microscan Systems, Inc. Microsonic Systems Inc. Miltenyi Biotec GmbH MiniFab (Aust) Pty Ltd Minitubes MipTec Moeller Medical GmbH Molecular Devices (New Milton) Ltd Molecular Devices, Inc. Multispan, Inc. Nanion Technologies NanoScreen, LLC Nature Publishing Group New England Small Tube Corporation Nexus Biosystems NSK Americas Nymotion LLC Omega Bio-Tek, Inc. Omni International, Inc. Opticon, Inc. Pacific - iD Pall Life Sciences Parker Hannifin Automation & Fluidics PBC Linear, a Pacific Bearing Co. Peak Robotics, Inc. PerkinElmer PharmaDiagnostics BV PHENIX Research Products Pittcon Plastic Design Corporation Plexera LLC Precise Automation Prestwick Chemical, Inc. Pro-Dex, Inc. 22 | SLAS2012.org Process Analysis & Automation Ltd Progeny Software, LLC Promega Corporation PSS Precision System Science QIAGEN Sciences, Inc. Quantifoil Instruments GmbH ReproCELL ReTiSoft Inc. Roche RTS Life Science RURO, Inc. SAGE Publications Sarstedt, Inc. Schaeffler USA SCIENION AG Scigilian Software, Inc. Scinomix, Inc. Seahorse Bioscience SelectScience SensiQ / ICx Nomadics Seyonic SA Sias AG Sigma Life Science SiLA Consortium Siloam Biosciences, Inc. Solid State Cooling Systems Sophion Bioscience A/S Specs SPEX SamplePrep LLC SRU Biosystems, Inc. STaCS DNA, Inc. STARLIMS Corporation Stäubli Corporation Steinmeyer Inc. STRATEC Biomedical Systems AG Swisslog TAP Biosystems Tecan Technology Networks Ltd Thermo Scientific Thorlabs Titertek - Berthold Titian Software TOMTEC Torrey Pines Scientific, Inc. TriContinent TRINAMIC Motion Control GmbH & Co. KG Trinean TTP LabTech Ltd TWD TradeWinds, Inc. TubeWriter UNIConnect Union Biometrica, Inc. USA Scientific, Inc. V&P Scientific, Inc. Venenum BioDesign VICI Valco Instruments Wako Laboratory Automation Watson-Marlow Pumps Group Weidmann Plastics Technology AG Wheaton Science Products Wyatt Technology Corporation Xavo Systems AG Xiril AG Yole Développement Zinsser Analytic Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Travel and Hotel Information Join us at SLAS2012 in Beautiful San Diego Be a part of the excitement surrounding this premier world-class scientific event where leaders within the laboratory science and technology community will come together in beautiful San Diego, California. The San Diego Convention Center overlooks spectacular Coronado Bay, filled with colorful sailboats, spectacular yachts, and massive aircraft carriers. Where you can walk just three blocks and discover urban galleries, and boutiques. And where within just a few minutes north, south, east or west, you can find not only rural orchards, and ranches set against a dramatic North American desert, but world-class biomedical research centers, seaside restaurants and exquisite Pacific sunsets. SLAS2012 Smart-Savers Program To help make the SLAS2012 experience both affordable and well-founded, SLAS has developed the SLAS2012 Smart-Savers Program. The cost-savings program offers SLAS2012 participants early-bird registration discounts; discounted registration for groups; short course registration discounts, and special hotel pricing. SLAS also offers complimentary SLAS2012 registration for academics and unemployed professionals. Be sure to check out SLAS2012.org/conference/smartsavers.cfm to secure your savings. Hotel Information SLAS2012 has contracted with two of San Diego's premier convention hotels the San Diego Marriot Marquis & Marina and the Hilton San Diego Bayfront for event participants. The deadline to secure hotel rooms at the SLAS2012 group rate is January 5, 2012. Make your reservations online for immediate confirmation of hotel at SLAS2012.org/conference/travel.cfm. Please have your credit card and arrival/departure information ready when making reservations. By booking within the official hotel block, you ensure that you will receive: ºº ºº ºº ºº ºº The best rate available at these hotels for the duration of your stay Complimentary internet in all guest rooms Complimentary access to the hotel fitness center Guaranteed reservations and email confirmations for each reservation Ease of booking using the designated SLAS2012 booking portals San Diego Marriott Marquis & Marina (Headquarters Hotel) $229 Single/Double Occupancy (does not include state and local tax) ºº ºº Telephone Reservations: +1.619.234.1500 (Be sure to reference “SLAS2012” when booking via telephone.) SLAS2012.org/conference/travel.cfm Hilton San Diego Bayfront $229 Single/Double Occupancy (does not include state and local tax) ºº ºº Telephone Reservations: +1.800.445.8667 (Be sure to reference “SLAS2012” when booking via telephone.) SLAS2012.org/conference/travel.cfm Please Note: Your patronage of these official meeting hotels makes it possible for SLAS to secure the space necessary for this event at greatly reduced costs. The hotels not only offer discounted rates and the best networking opportunities, but staying in the official hotels helps SLAS meet its obligation to the hotels, avoid penalties, and keep meeting registration prices down. Thank you in advance for your support. Air Travel Information You may book your air travel directly with SLAS2012’s official travel agent, Travel Focus. [email protected]; +1.800.756.2987 (domestic); +1.214.915.9448 (international) American Airlines is the official carrier of SLAS2012. Receive a 5 percent discount off the lowest applicable published fare on AA flights. If you use your own travel agency, please reference American Airlines Authorization Number 2422AU when booking to receive the discount. 23 | SLAS2012.org The JALA & JBS ART of SCIENCE CONTEST ber 6 15, Num Volume r 2010 Decembe JALA JALA (Fluorescent protein can do the craziest things!) devoted . nal forum internatio in the laboratory iplinary ology A multi-disc ent of techn ncem to the adva Volume Share your mesmerizing original scientific images with SLAS and you might win an 419–464 Pages ber 6, 15, Num 0 er 201 Decemb iPad 2 lop 10 es to deve ISSUE ATION20 Techniqu formation to SPECIAL OF LABAUTOM Winner: te T Award aggrega dow n mic roTHE BES vation g cell Inno rollin and top- e. for cont 2010 ALA ctur om- up From the microstructures r, and a bott tissue-like stru avio imic hydrogel stem cell beh creating biom ening and Scre roach to regu late mation ring app ratory Auto eng inee al of the ial Journ An Offic SLAS.org ty for Labo Socie 0 PM 010 2:24:1 11/3/2 or One of Ten $50 Amazon.com Gift Cards Interesting, beautiful or just plain COOL! Visualization plays an important role in the analysis and presentation of scientific work. In journal articles, images often communicate ideas and information in ways that text, tables, charts, graphs or equations cannot. Sometimes scientific images surpass this purpose and create shapes, patterns and designs that capture attention and imagination. These are the images JALA and JBS seek for the 2011 Art of Science Contest. Here’s How: Here’s Why: E-mail a high resolution jpg file (300+ dpi/10MB maximum size) of your favorite cell structures, assay results or other lab creations to [email protected]. Include your first and last name in the title of the jpg file AND include your name, contact information and a brief description of your image in your message. One grand prize winner will receive an iPad 2. Up to ten honorable mentions may be awarded and each will receive one $50 Amazon.com gift card. In addition, entries will be celebrated in the SLAS Member Center at SLAS2012, at SLAS.org and Facebook, and the grand prize winning entry will be shared with the media. One winner per entry. Here’s When: Entries must be received by e-mail before 10:00 p.m. on Thursday, December 2, 2011. Entries are welcome from SLAS members and nonmembers. Judges’ decisions are final and subjective. One winner per entry. By submitting an entry, all participants must agree to these terms: • I grant SLAS the right to copy, distribute, publish, display and otherwise use the photos and text submitted for purposes of the Bio Art Blast Off program or for any advertising or publicity on behalf of the program or other similar future programs. Questions? Contact Nan Hallock at [email protected] or +1.630.256.7527, ext. 106. • I agree that the submitted photos and text may be cropped, edited, electronically manipulated or otherwise altered, and that whether the photographs are used is entirely for SLAS to decide in their sole discretion. • I certify that I am the photographer and sole copyright owner of the submitted photos and text, or I have the owner’s permission to submit such photos, and I have obtained the consent of all identifiable persons shown in the photos for these uses. • I agree to reimburse SLAS for all damages and expenses (including attorney’s fees) they may incur from claims based on their use of my submitted photos or text. • I understand and accept that use of any personal information I submit will be governed by SLAS’s privacy policy. • I am at least 18 years old and have full legal authority to transfer these rights to SLAS. Presented by the Official Journals of the Society for Laboratory Automation and Screening Journal of Biomolecular Screening and Journal of Laboratory Automation Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Start the search at SLAS Career Connections. SLAS Career Connections is one of the select few highly discrete, automated employment programs that brings together its online professional services with its respected career center and development sessions at SLAS2012. Student and Early Career Professionals Program Life After Graduation and Career Coaching Instructor: Professor Daniel J. Eustace, Ph.D., University of Connecticut Join us for one or both of our FREE career related workshops. Monday, February 6, 7 – 8:15 am Job Seekers Job Seekers may submit résumé online through the SLAS website and on-site in San Diego, browse the job boards, meet one-on-one with a career coach and network with recruiting professionals. How to Network at a Technical Meeting This session will review critical activities that can make a difference for you in your job search — networking conversations, practice with small talk, listening skills and body language. Résumé and Cover Letter Writing Learning how to structure and what to say clearly and briefly is critical to having reviewers read it and select you for interviews. Human Resource Professionals and Recruiters With 5,000 participants concentrated at SLAS2012, our career center substantially narrows the applicant pool to very highly qualified prospects. Start the search at SLAS Career Connections. Get started today for more information about Career Connections, visit: SLAS2012.org/conference/career.cfm Career Coaching Sessions Monday, February 6 and Tuesday, February 7 from 10 am – 5 pm One-on-one career counseling sessions to conduct mock interviews and review résumés, available by appointment at SLAS2012 in the SLAS Member Center. Contact Carol Brady, SLAS Member Services Coordinator to schedule your appointment at [email protected]. Tuesday, February 7, 7 – 8:30 am The Interviewing Continuum An opportunity to look in the mirror and see yourself as a candidate for a professional position. Mock Interviews This workshop will teach interviewing principles by conducting mock interviews with members of the audience. Student and Early Career Professionals Mixer at SLAS2012 Monday, February 6, 5 – 6 pm; SLAS Member Center Interested in becoming involved with SLAS? SLAS welcomes student attendees and Academic Travel Award winners to SLAS2012 with this social event designed to help students connect with each other and with SLAS Volunteer Leaders. Drinks and snacks will be served. 25 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org SLAS2012 Annual Conference Program Committee, SLAS Scientific Program Advisory Committee, SLAS Board of Directors Informatics Track SLAS2012 Annual Conference Program Committee Andrew Su, Chair Scripps James Gill, Ph.D., Associate Chair Bristol-Myers Squibb Company Daniel Sipes, M.S., Co-Chair Genomics Institute of the Novartis Research Foundation Micro- and Nanotechnologies Track David Eddington, Ph.D., Chair University of Illinois at Chicago Elliot Hui, Ph.D., Associate Chair University of California, Irvine Frank Fan, Ph.D., Co-Chair Promega SLAS Scientific Program Advisory Committee William Janzen, Ph.D., Chair University of North Carolina Frank Fan, Ph.D. Promega Assay Development and Screening Track Hakim Djaballah, Ph.D., Chair Memorial Sloan-Kettering Cancer Center Andrew Napper, Ph.D., Associate Chair Nemours Center for Childhood Cancer Research Jonathan O'Connell, Ph.D. Bristol-Myers Squibb Company Daniel Sipes, M.S. Genomics Institute of the Novartis Research Foundation Aaron Wheeler, Ph.D. Toronto University Bioanalytical Techniques Track Kamlesh Patel, Ph.D., Chair Sandia National Laboratories Thomas Perroud, Ph.D., Associate Chair Illumina, Inc. SLAS Board of Directors Michelle Palmer, Ph.D. Broad Institute of Harvard and MIT David Dorsett, M.B.A. Bristol-Myers Squibb Company Diagnostics Track Anson Hatch, Chair Sandia National Laboratories Erik Rubin, Ph.D. Bristol-Myers Squibb Company Andy Zaayenga John Robinson, Associate Chair High-Res Biosolutions Abbott Laboratories Jason Abbas, M.S. Syngenta Seeds Drug Target Biology Track Michele Cleary, Ph.D., Chair Merck & Co., Inc. Haian Fu, Associate Chair Emory University Robert Ames, Ph.D. GlaxoSmithKline Bill Janzen University of North Carolina at Chapel Hill Jeff Paslay, Ph.D. Paslay Consulting Group High-Throughput Technologies Track Timothy Dawes, Ph.D., Chair Mary Jo Wildey, Ph.D. Merck Research Labs Genentech Jonathan Lee, Associate Chair Eli Lilly and Company 26 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Sponsors That Make SLAS2012 Possible Premier Sponsor: An exclusive sponsorship, SLAS thanks Agilent Technologies for underwriting a number of this year’s conference activities, student grants and the Tuesday Gaslamp Block Party Bash in the heart of downtown San Diego. Diamond Sponsors: Platinum Sponsors: Gold Sponsor: Silver Sponsor: Barcode Label Solutions To reserve your sponsorship or for more information please contact: Mary Michalik, Sponsorship Manager; [email protected]; +1.312.265.9650 27 | SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 Media Partners That Make SLAS2012 Possible Media Partners: 28 | SLAS2012.org SLAS2012.org Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 Scan the code with your smart phone to go directly to SLAS2012.org. Conference and Short Course Registration Form Register online at SLAS2012.org or complete this form. A $50 cancellation fee will be charged on cancellations received on or before December 31, 2011. No refunds will be given on cancellations received after December 31, 2011. First Name Last Name Year of Birth School Obtained Highest Degree Job Title/Year Hired Company Name Highest Degree/Year Earned What is Your Current Salary q Work q Home Preferred Mailing AddressStreet Address City State/Province Zip/Postal Code Country TelephoneFaxEmail q Check this box if you do not wish to be included in promotional mailings or faxes from Exhibitors sent prior to SLAS2012. Employment Sector: (check only one) q Academia/Institute q Agriculture q Chemical Industry q Clinical Diagnostics q Consumer Products q Contract Services q Drug Discovery q Drug Development q Energy Generation and Petrochemicals q Financial/Investment q Forensics and Security q Food q Government q Technology Provider q Other:__________________________ Purchasing Involvement: (check only one) q Approver/Final Decision Maker q Influencer q Not involved in buying decisions q Specifier q Other:__________________________ Classify Your Current Position: (check only one) q Academic Dean, Provost, Department Head q Account Executive q Administrative Support q Attorney/Legal q Consultant q Directorq Editor/Reporter q Finance q Intern q Lab Specialist/Technician q Licensing q Manager/Department Head q President/CEO/Corporate Officer q Professor q Purchasing q Retired q Sales/marketing/Business Development q Scientist/Engineer/Research q Student-Undergraduate q Student-Graduate q Student-Post Doctoral q Vice President q Other:__________________________ Primary Area of Interest: (check only one) q Assay Development and Screening q Bioanalytical Techniques q Diagnostics q Drug Target Biology q High-Throughput Technologies q Informatics q Micro- and Nanotechnologies q Other:__________________________ Your Additional Member Organizations: (check all that apply) q American Academy of Forensic Scientists q American Association of Pharmaceutical Scientists q American Association of Clinical Chemistry q Association of Laboratory Managers q American Chemical Society q American Institute of Chemical Engineers q ASBMBq American Society of Microbiology q Clinical Laboratory Management Association q International Association for Food Protection q Institute of Electrical and Electronics Engineers q Institute of Food Technologists q International Society for Pharmaceutical Engineering q ISSCRq Laboratory Robotics Interest Group Other Meeting(s) You Attend: (check all that apply) q ACHEMA q American Association of Clinical Chemistry q American Academy of Forensic Scientists q American Association of Pharmaceutical Scientists q American Chemical Society q American Institute of Chemical Engineers q Association of Laboratory Managers q American Society of Microbiology q Clinical Laboratory Management Associationq European Lab Automation q LRIG/ELRIG q microTAS continued on next page. q Institute of Food Technologists q MIPTECq None Short Courses: February 4–5 Conference: February 6–8 Exhibition: February 6–7 SLAS2012.org Conference and Short Course Registration Form Conference Registration On or Before October 31 Between November 1 and December 12 After December 12 Member Non-Member Member Non-Member Member Non-Member $810 $1,050 $900 $1,050 $1,110 $1,250 $270 $450 $300 $450 $400 $550 $25 FREE $25 FREE $25 FREE $25 FREE $25 FREE $25 FREE Industry Participant Academic/Government Participant Student Participant* Exhibits Only Participant** *Full-time students ONLY are eligible for this rate. Student ID is required to register. Student must register using the PDF form. **Registration is required. Those without badges will not be allowed access to the Exhibit Hall. Short Courses Check box of selected course. (Short Course registrations include entrance into the Exhibits.) Industry Academic/ NonGovernment Member Member $650 $275 $650 $275 $650 $275 $650 $275 Industry Member Saturday, February 4, 2012, One-Day LIMS in the Organization Sample Management: Best Practice, Trends and Challenges Establishing Cell-Based Assays for Screening Applied Information Technology for the Laboratory Automated Liquid Handling in Accredited or Forensic Environments Liquid Handling Boot Camp (Hands-On) Introduction to Laboratory Automation Automation for In Vitro Diagnostics Electronic Laboratory Notebooks Quantitative Evaluation of Screening Assays for Drug Discovery $550 $550 $550 $550 $550 $650 $275 $325 $25 $650 $550 $550 $550 $550 $750 $650 $650 $650 $650 $375 $275 $275 $275 $275 $425 $325 $325 $325 $325 $25 $25 $25 $25 $25 $325 $325 $325 $325 $25 $25 $25 $25 $550 $550 $550 $550 Second Course for Industry Member $440 $440 $440 $440 $650 $650 $650 $650 $275 $275 $275 $275 Second Course for Academic/ Government Member $220 $220 $220 $220 $650 $520 $750 $375 $300 $425 $25 $650 $550 $650 $550 $520 $440 $520 $440 $750 $650 $750 $650 $375 $275 $375 $275 $300 $220 $300 $220 $425 $325 $425 $325 $25 $25 $25 $25 $550 $440 $650 $275 $220 $325 $25 $550 $440 $650 $275 $220 $325 $25 $650 $520 $750 $375 $300 $425 $25 $1,170 $1,350 $495 $675 $585 $765 $50 $50 Sunday, February 5, 2012, One-Day Label-Free/Biophysics Methods for Screening Pharmacokinetics and Pharmacodynamics in Drug Discovery Automated Assays for Drug Discovery Technical Project Management Automating Scientific Data Analysis and Visualization With Excel and VBA (Computer-Based) Liquid Handling Boot Camp (Hands-On) Writing Testable and Verifiable User Requirements XML for the Laboratory (Computer-Based) Introduction to Laboratory Automation High Content Screening: Instrumentation, Assay Development, Screening, Image and Data Analysis Next Generation Sequencing Technologies and Automation introduction Introduction to Design of Experiments (Computer-Based) Saturday and Sunday, Two-Day Microfluidics I/II Getting Started With Excel and VBA (Computer-Based) Academic/ Government Student Non-Member $325 $25 $325 $25 $325 $25 $325 $25 $990 $1,170 Questions? Call: +1.866.878.0747 (toll free in US Only) or +1.708.486.0747 Membership: Conference registration discounts are available to SLAS members. For membership information go to www.slas.org. Send to: SLAS2012 Registration, P.O. Box 6271, Broadview, IL 60155-6271 or +1.708.344.4444 [fax] Conference Payment: Enter conference registration amount $ _______________ Enter short course amount $ _______________ Total amount: _______________ Please include payment for the total amount. q Check enclosed (U.S. funds, payable through U.S. bank). Please make checks payable to SLAS2012. q Credit Card: MasterCard, Visa, American Express, Discover number Exp. Date Authorized Signature Name as it Appears on Card Terms and Conditions: By signing this SLAS2012 registration form, I “the conferee” acknowledge and agree to the terms and conditions as posted on the SLAS2012 website (SLAS2012.org). Signature In Case of Emergency: This year we are asking that you please provide your cell phone number: _______________________________________. This number will only be used in the event of an emergency at SLAS2012. It will not be used for marketing purposes or stored in your permanent member record. Should an emergency situation arise in San Diego, you will receive a text message sent to this cell phone number with instructions regarding the situation. Should you require special assistance due to a medical disability, please contact SLAS Headquarters at +1.877.990.SLAS (7527)