Trauma – Update from Clinical Examples
Transcription
Trauma – Update from Clinical Examples
Trauma – Update from Clinical Examples Paul D. Eleazer University of Alabama at Birmingham DDS 1947 Waycross 6 7 8 5 3 2 9 1 4 1 Guidelines Guidelines are not guarantees Guidelines change Most trauma guidelines are based on anecdotes / “Expert Opinion” Very few good research projects exist Background Andreason, Danish oral surgeon - schools AAE Guidelines – 20032004 Pedo’s are different Recent lit. Dentaltraumaguide.org Exhaustive database Thousands Since Great 1962 example of EBD Many categories have few examples Jens Andreasen, et al. 2 Risk / Prevention Girls fall / Boys fight (sports) Primary tooth injuries peak @ age 2-3 Permanent tooth injuries peak @ 9-10 Trauma to the oral cavity is a Huge public health problem worldwide Risks Young Male Previous trauma Crown fracture is most common Procumbent Anteriors 3 Prevention Helmet with Facemask Motorcycle trauma Football Mouthguard Distributes May force transmit force to spine, brain Outline Assessment Physical Exam History Radiography Head and Neck Exam Cases Prognosis / Follow-up visits MD / Emergency Room Referral Tetanus – wi/ 5y=OK C-spine Swallowed / Aspirated matter Soft tissue suturing ? 4 Smooth Muscle in Artery will stop bleeding, IF CLEAN CUT artery Capillaries and veins continue to bleed Middle Meningeal Artery Passes into cranial vault in central base of brain Ragged Tear 5 Brain Movement = Easy to break MMA Hematoma from ruptured MMA Brain protein between microtubules ruptures with force Shenoy, U Penn, Biophys J, 2013 Microtubules inside neurons are paths for chemical transport, protein (tau) between tubules breaks when the brain moves too much and stops suddenly. Neurons lose function(die) 6 MD / Emergency Room Referral Tetanus – wi/ 5y=OK C-spine Fx Swallowed / Aspirated matter Soft tissue suturing ? Occipital Artery tear? CSF leak Basilar Skull Fx Bleeding from ear canal = really bad Assessment - History Force- direction and magnitude Did tooth move? Bleed? Consider fulcrum for fx. Soft tissue Tear ? PDL Compression ? Root / Bone Fracture ? 7 Assessment – Dental X-rays Different horizontal and vertical angles Cervical spine views for vertebral fx. See fx / resorption Vertical angle radiographs Is this a fx? What about this? Change vertical angle 8 Assessment – Clinical Exam Mobility / Percussion (Auscultation) Displacement Indicates Confirm PDL tear that root is repositioned Splint Pulp tests (negative not reliable) Discoloration = Intrapulpal Bleed Foreign material embedded in soft tissue Validity of Pulp Tests, All Cases Linda Levin, JEndo 12-09 and Andreasen text 3rded. pp. 196-215 EPT-sensitivity=.71-.93, specificity=.92-.96 Cold – .68-.92 .70-.93 Heat – .68-.86 .41-.81 Laser Doppler 1.0 1.0 May need to wait 6 w. for accurate test (longer?) + test early = very good sign The Trauma Continuum Concussion Fracture – enamel only; enamel + dentin; crown only; w/ or wo/ pulp exposure Discolorations Subluxation and Luxation Intrusion – surgical reposition or orthodontic extrusion Extrusion – Lateral Avulsions – Replanted in field, in mouth, in Medium, dry time / Ankylosis Resorptions Fractures Pulpal Regeneration 9 Cases: Concussion Fractures – crown – root Intrusion Subluxation Luxation Avulsion Resorption Ankylosis Bone fracture Pulp Regeneration Case Study Concussion Courtesy Dr. Jim Tinnin Check for foreign body in lip / tongue / lung / stomach Watch for symptoms Microfracture of enamel ? Concussion can allow bacteria into pulp Love, Endod Dent Traumatol 1996 16 Intact teeth received impact injury No visible fracture or luxation 7 had bacteria in pulp Conclusion: Micro enamel/dentin infractions May be wise to seal enamel 10 Concussions usually heal BUT, can result in pulp necrosis Cases: Concussion Fractures – crown – root Intrusion Pulp cap Subluxation Pulpotomy Luxation Pulpectomy Avulsion ______ Resorption Soft tissue Ankylosis Bone fracture Pulp Regeneration Crown Fracture enamel or enamel + dentin, w/ or wo/ pulp exposure Bonded restoration / Bond piece back on Pulp Cap (Frank or near exposure) Pulpotomy Pulpectomy (Apexification/Apexogenesis) Pulp prognosis degrades w/ larger exposure, time open, pt’s healing, pulp blood flow 11 Enamel Only Fractures BUT #8 Discoloration = Previous Trauma Dr. Jim Tinnin Enamel and Dentin, Pulp Intact Dr. Jim Tinnin Where did the Incisal Edges go? Lip ? Bacterial ingress into pulp minimal for few days, (extreme thermal pain) Dr. Jim Tinnin 12 Crown Fx = energy dissipated = usually heals Rule Breaker Why Endo ? Accident history may have disclosed a bodily blow in addition to enamel fracture Two (+) Blows Tooth Loose ? 13 Two Blows #7 and 8 needed endo – #9 healed OK Get a Good history Concussion in addition to dentin-enamel fx Required Endo #7 & 8 Pulp Cap Excellent prognosis Inflammation at 48 h is 2 mm into pulp Cvek, JOE 1982 Harran-Ponce, Bacteria invade pulp (superficial) Dent Tramatol 2002 Why wait? Treat ASAP Calcium hydroxide MTA 14 Let’s Build a Chart Closed Apex Prognosis (Statistics mean nothing if you are the one) Pulp OK Pulp cap = 99% Pulp Prognosis (open apex =10% better) Pulpotomy Cut to level where bleeding stops by itself (No vasodilation = no inflammation) Best wound with water-cooled large round diamond Granath & Hagman Deep pulpotomy w/ open apex MTA ? Pulpectomy Max. Time before pulpectomy: 11 days 11 (Andreasen) Sooner is better ! External resorption visible microscopically Apexification vs. apexogenesis (pulp vital) Conclusion: Pulp tests not reliable 15 Always, Always, Always Use a Rubber Dam File Appendix Pulp Exposed 4-98, MTA Pulpotomy Dr. Jim Tinnin Pulp Still OK @ 40 m. APRIL ‘98 Dr. Jim Tinnin AUGUST ‘01 16 Soft Tissue Laceration (multiple small sutures) Abrasion Contusion (bruise) Debride well Heals better if moist (Neosporin Ointment) Peridex for intraoral wounds Neosporin has 3 antibiotics, Ointment stays moist Neosporin + pain relief swaps bacitracin for local anesthetic “N” Drugs antibacterial antifungal Neosporin (Neomycin, Polymyxin B, analgesic) External topical, not absorbed thru skin Neomycin – absorbed thru m. memb. Nystatin (N.Y.State lab) disrupts fungal cell walls, topical, oral (not absorbed) Nizoral (ketaconazole) inhibits fungal sterols, our corticosteroids, oral dosing systemic absorption 17 Gray Discoloration Acute – Bleeding, may heal (rare) Chronic – Old bleed, pulp necrosis (likely) The gray primary tooth of longstanding bleeding intrapulpally may be necrotic, and thus a risk to succedaneous tooth What about old trauma ? Pulp necrosis Possible damage to 2° t. Endo ZOE Stay fill absorbs wi/ canal Bumped & Discolored = Intrapulpal Bleed 18 Yellow Discoloration From Andreasen text Calcific metamorphosis May take many years for pulp necrosis F. Andreason Eur. DJ 1987 and Jacobsen JDR 1977 say 1% per year chance of pulp necrosis after calcific metamorphosis But a serious clinical problem to treat nonsurgically I say: Follow for 1 year, & do endo if canal closing Yellow Discoloration Calcific Metamorphosis -typically occurs during 1st year Why did it abscess ? Dr. Jason Sayer 19 Calcific Metamorphosis patient - dead stop - note lateral position of radiolucency Dr. Jason Sayer Calcific Metamorphosis patient - note lateral canal Dr. Jason Sayer 3-4 mm shorter #8 high school football trauma Now age 74 and painful 74-17 = 57 ! 20 65 y o female #7 pain Calcific metamorphosis or deep restoration calcified canal ? Status of #8? Bleaching 30% H2O2 is too strong Cases of external resorption Need to make a seal at cervical Sodium perborate Slower Less potential damage Slightly over bleached, probably will return OK From Google Images 21 External vs. Internal Bleaching H2O2 reaches pulp wi. 15 min. (Cooper, JOE, 92) Apparently pulp neutralizes chemical wo/ permanent damage Sensitivity often increases dramatically (weeks) Carbamide peroxide = 1/3 of [H2O2] Heat degrades proteins (not for vital bleach) Healing = Sometimes a surprise What killed 49 years ago the patient received intracanal bacteria ? a trauma to #9, with subsequent pain then drainage. The patient, then a 16 year old girl, refused to allow extraction. The dentist attempted endo, but the drainage persisted for several years (with the patient still refusing extraction). Eventually the drainage stopped – WHY ? Asymptomatic w/ good bone, but crown fx at age 65, endo thru crown Resorption @ root end First file size = size at pulpal death 3 year recall, new crown 22 Fell and Bumped Chin Trauma to Mandibular Anteriors How Many Need Endo ? Test Max. too 7 Month Result – Asymptomatic, Lateral still tests vital Bone fill beginning Cases: Concussion Fractures – crown – root Intrusion Subluxation Luxation Avulsion Resorption Ankylosis Bone fracture Pulp Regeneration 23 Crown–Root Fracture Auto Wreck Extract small piece and evaluate Horizontal position = fx. after crown Crown usually prevents this iatrogenic ? This is very rare 24 Root Fracture Angle and Force of Blow of Fracture ? Mobility ? Level Splint 3-4 weeks or more Hope for cementum “callus” Post that lutes two pieces ? avoid cement into bone Some Possible Fractures Cusp Fx. Incomplete Fx. Hopeless Do these exist ? Fractured from apex: Natural or Spreader ? 25 Mobility Issue Apical segment did not move, and is likely vital When to debride pulp ? Do MTA to fracture ? Move broken part in and splint Dr. Chris Fleming Horizontal Root Fx. Usually apical segment is vital Avoid cement in fracture line Severe Inflammation Old Trauma, Failed Pulp Cap G-P Fill @ 6 m External Resorption Dr. Jim Tinnin Ca(OH)2 x 6 m 26 Cut threads is apical segment and draw coronal part tight Minimal threads needed Seal canal w. MTA slurry ? Treatment for Crestal Level Fx. or Intrusion of whole tooth Surgical extrusion Orthodontic extrusion Implant 27 Bone Crest is least favorable root fracture Kerbl & Eleazer Root Fracture Traumatic decoronation #22 Kerbl & Eleazer Cases: Concussion Fractures – crown – root Intrusion Subluxation Luxation Avulsion Resorption Ankylosis Bone fracture Pulp Regeneration 28 Intrusion Very poor pulpal prognosis High risk to succedaneous tooth Surgical extrusion Orthodontic Extrusion Antibiotic(s) in canal may decrease ext. root resorption Prognosis Pulp Prognosis is Based on: Root Prognosis is Based on: Time of compression of vessels (1-2 hours ?) Damage to cementum / PDL and infection Intrusion Controversy Andreasen says pulpal necrosis almost 100% External resorption highly likely. My dental school: Let it re-erupt Saroglu (OOO2006 – 102(4):e60-5. 5 cases of permanent teeth w/ open apexes that spontaneously re-erupted 29 Let it Re-erupt ? Wigen (Dent Traumatol 2008) 35 of 37 primary teeth re-erupted in 3-12 months 7 forcefully erupted w/ surg and 7 w/ ortho 43% remained vital @ 4 y. (range 1-12y) Cunha (Endodont Dent Traumatol 1995) blow in dog deep intrusion re-erupted wi/2 months Severe All O.R. Case - Intrusion, Surgical Access to Linguals Dr. Brad Alley 9-04 8 w post trauma, Mixed Dentition = no ortho extrusion Open Apexes MTA Fills Bradley Alley 9-04 30 O.R. Case Bradley Alley 9-04 MTA Fills Orthodontic Extrusion Endo Post w/ hook (cut trans-septal fibers) Elastic traction to ortho wire (1 week) Stabilize (1 month) Ortho wire allows direct extrusive force from hook cemented in canal 31 Elastic in position Ortho Extrusion - 5 mm in 1 m. Dr. Mark Essner Ortho Extrusion Courtesy Dr. Frank Kerbl Gingivectomy to allow pulpectomy 32 Cases: Concussion Fractures – crown – root Intrusion Subluxation – Moved, but back in place by itself Luxation = PDL tear Avulsion Resorption Ankylosis Bone fracture Pulp Regeneration Case Study Subluxation (PDL tear, moves back into position) Check occlusion Splint (none / light for 7-10 days) Pain pills (NSAIDs) Soft diet CHX rinse bid Sub-Luxation or Luxation Note Wide PDL Is Occl. OK? 33 Closed Apex Prognosis (Statistics mean nothing if you are the one) Pulp OK Pulp cap = 99% Resorption / PDL Concussion = 90% Subluxation = 75% -Calcif. Meta.10% 20% Pulp Prognosis (open apex =10% better) Cases: Lateral, Extrusion, Intrusion Concussion Fractures – crown – root Intrusion Subluxation Luxation - Still out of place, ? Blood supply Avulsion Resorption Ankylosis Bone fracture Pulp Regeneration Luxation (Moved but still in socket) Check occlusion Splint (none / light for 7-10 days) Pain pills (NSAIDs) Soft diet CHX rinse bid 34 Luxations Lateral luxation Intrusive luxation Extrusive luxation Splint lightly for 1-2 w. Bone fracture needs more stability x 6-8 w. Some mobility prevents ankylosis Splint If you MUST Maybe no splint Light, brief = reduce ankylosis w/ movement Bond wire or heavy fishing line mesh Attach to firm teeth first, traumatized one last Titanium Splint 3-4 weeks (longer)(more rigid) for alveolar fx or mid-root fx (avoid cement in fx.) Not like this ! 35 Attach wire to sides, then lute avulsed teeth Debride canals ASAP, Splint for 10 days, Ca(OH)2 for ___ TTS Titanium mesh splint Adatia & Kenny J Cal Dent Assoc 2006 Patterson Dental $47.00 Von Arx et al Dent Traumatol 2001 Medartis 36 Estimate Force, Direction Facial plate fractured & root trapped Pressure may result in resorption, or fracture Must pull down to reposition How far will pulpal vessels stretch before rupturing? About 2 mm Plan on Endo if moved >2 mm, dying pulp has NO BENEFIT, remove ASAP Can vessels ends rejoin ? Maybe, but rare 37 Closed Apex Prognosis (Statistics mean nothing if you are the one) Pulp OK Pulp cap = 99% Resorption / PDL Concussion = 90% Subluxation = 75% - Calcif. Meta. 10% 20% Extrusion = 15% - Calcif. Meta. 60% 20% Lateral lux. = 10% - Calcif.Meta. 60% Alveolar fx. = 10% Intrusion = 0%??? Root Fx. = varies – PDL/resorption 60% 30% 100% 100% Pulp Prognosis (open apex =10% better) Cases: Concussion Fractures – crown – root Intrusion Subluxation Luxation Avulsion Resorption Ankylosis Bone fracture Pulp Regeneration Avulsion = out of socket Replanted in field In milk Saliva Saline Gatorade Out , 30 min. (AAE: 1 hour) Dry > 30 min. (AAE: 1 hour) 38 Replant Permanent Teeth If not out too long If not mistreated (Kleenex) Tetanus Antibiotics Splint briefly 50% PDL strength @ 2 w PDL strength @ 8 w. 100% Avulsions: Clot in socket Open apex Remove gently or Not (do not damage PDL) Dry > 1 h. = generally not rec. to replant Closed apex Endo for sure Pulpectomy ASAP Antibiotics + corticosteroid in canal Avulsed Primary teeth Do not replant due to damage to succedaneous t. Tooth may already be damaged Infection may aid / cause resorption 39 Primary tooth injury can impact tooth bud Study force Treat before infected Generally, extract damaged primary tooth Primary Tooth Luxated / Avulsed = Leave It Out Dr. Jim Tinnin This is a Problem ! Permanent Teeth Avulsed in Mixed Dentition Dr. Jim Tinnin 40 Best Case Avulsion Replanted in field Hold by crown, rinse, replant (even backward) Light splint x 7-10 days (No splint) Endo ASAP Antibiotic / Tetanus (TIG / booster after 5 y. / q 10 y for all) 50% PDL strength @ 2 w (100%@8w) Mandell Avulsed Tooth “high” Compress clot, maintain pressure Occlusal adjustment May need splint 2nd best In mouth Saliva is good Hold in mouth (Do not swallow) Antibiotic Tetanus 41 In transport medium Via-Span Hank’s Balanced Salts solution Milk Physiologic saline Antibiotic Tetanus Cases: Concussion Fractures – crown – root Intrusion Subluxation Luxation Avulsion Resorption - Internal – External Replacement – Inflamm. Ankylosis Bone fracture Pulp Regeneration Long time Out, Dry Case of long dry time (Kleenex)(1/2 to 1 h) Strip Soak PDL to minimize foreign body rejection in fluoride to retard resorption Bisphosphonate ? Emdogain, GEM 21, other growth enhancer(s) Load canal w/ calcium hydroxide / iodoform Antibiotic Tetanus 42 Straumann Emdogain 1-800-448-8168 Made from pig tooth buds in Sweden Works nicely in perio Again available in US US FDA banned in 2007 until factory passed inspection Chemically remove smear layer and apply to root Growth- Factor Enhanced Matrix 21s GEM 21s Osteohealth – 631-924-4000 Recombinant Platelet-Derived Growth Factor (rhPDGF-BB), and a synthetic bone matrix, Beta-tricalcium phosphate (ß-TCP) FDA approved (2006) for perio regeneration Case Study Traumatic Extrusion time Extruded 1 month ago Pulp #8 test vital to cold and EPT Splint ? Occlusion ? 43 Oblique Fracture 1. Drill canal to size X-Trac Device 2. Thread in self tapping screw 3. Place plate over tap-screw 4. Apply pressure w/ jack screw A-Titan Instruments $2500.00 877-284-8261 Hamburg, NY Implant Bone Graft at 6 w. 44 Resorption – need break in pre-dentin / pre-cementum Problem: Damage from trauma or forceps to reposition tooth Internal External Inflammatory Replacement (ankylosis) Osteoclasts activated by inflammation Replacement Resorption (Ankylosis) Poor Prognosis Body “sees” dentin as bone Rapid External Resorption Inflammation 2 weeks after Ca(OH)2 Concussion from Horse Kick Ca(OH)2 in canals failed on #7. Note crestal bone loss. 45 Note Irregular Outline of Pulp w/ External Resorption Internal Resorption – Excellent Prognosis – Did not Perforate to PDL Blood Supply Internal resorption ? Prognosis May have begun externally True internal resorption has excellent prognosis if treated before perf. into PDL 46 Perforated facial of root = must do surgery, perio defect Geristore is best bet Geristore DenMat Dual Cure Hybrid Ionomer-Composite Very biocompatible Also need Etchant, Primer, Clear Matrix Strips, Finishing Instruments (#12 Blade, Burs, Sanding Strips) Geristore for external resorption 47 External Resorption May need a Cone Beam External Resorption at Epithelial Attachment, Extr. by Dr. Geurs Extensive weakening of tooth 48 Clinical Crown Esthetically bonded in Position - Dr. Liu Not like ortho resorption Almost always limited to apex Stops when force stops # 9 at 2 weeks after avulsion External Resorption (Inflammatory) Note #9 shorter than #8, perhaps a prior trauma ? 49 Reduce Resorption Calcium hydroxide Penicillin (Hammarstrom, Endo. Dent. Traumatol 1986;2:51-3) Tetracycline (Selvig, Scand JDR 1992;100(4):200-3) Stannous Flouride (ibid.) Corticosteroid (Trope,J Endo 2009;35:663-7) Calcium Hydroxide Decreases resorption Counteracts osteoclast’s HCl necrosis = stimulates osteoid Ca45 shows new calcium not from Ca(OH)2 Coagulation Antibacterial dentin (White JOE 2002) & Kills bone and nerve But it Weakens Sigma-Aldrich 800-558-9160 Calcium Hydroxide Needs a second germicide #10,945-2 $10.40/5g 50-50 Iodoform & Ca(OH)2 50 We have grown E. faecalis in Calcium hydroxide 2004 UAB Study Chris McHugh: E. faecalis grows in pH 11 Commercial preparations pH 10 USP Ca(OH)2 pH 12 2012 UAB Study Jason Latham: E. faecalis grows in Calasept (pH 12+) First growth after 4 m, now adapted and grows faster Dangers Ca(OH)2 Ahlgren OOO 2003 Other Calcium Hydroxide Overfill Accidents Sharma, OOO, May ‘08 51 Calcium hydroxide is dangerous Lindgren, J Oral Maxillofac Surg ‘02 Clorox accident JADA 2000 External Resorption 52 Stannous Fluoride + Doxycycline Selvig Scand J Dent Res 1992;100:200-3. Hx: 1% SnF2 chron. inflam. resorption/ankylos Exp: dog teeth extracted, dry for 45 min., 0.1% SnF2 x 5 min, then 1% doxy. X 5 min., 85% root surface OK @ 4 w. (control 33%) Dilute Stannous Fluoride caused less cell damage, while enhancing healing Corticosteroid in canal Kirakozova…Trope JOE 2009;35:663-7. Dog teeth 60 min. dry outcome measure: pdl healing 0.05% clobetasol intracanal 56% OK No healed systemic c/s 0.05% fluocinonide 32%OK control 14% OK My Thought Bacteria wi/ tubules may be cause of resorption Calcium hydroxide does not kill all bacteria (E. faecalis) Need second germicide to boost Ca(OH)2 I favor 50:50 w. Iodoform Vitapex has 22% silicone oil 53 Cases: Concussion Fractures – crown – root Intrusion Subluxation Luxation Avulsion Resorption Ankylosis Bone fracture Pulp Regeneration Ankylosis Sound (Auscultation) Only part of PDL may ankylose Block repositioning may work Endodontic Endosseous Stabilizer Tri-Lock™ Endodontic Titanium Implants Al Frank (Dent Clin N AM – 1967) Park Dental Research, NYC Courtesy: Dr. Robert Barfield – healing @ 2-3 y, failed at 6 y –angled out buccal 54 Cases: Concussion Fractures – crown – root Intrusion Subluxation Luxation Avulsion Resorption Ankylosis Bone fracture Pulp Regeneration Case Study Fractured alveolus Several teeth move Obvious on x-ray More rigid splint x 3-4 weeks or more Intermaxillary fixation (vomiting danger) Displaced apex (to labial) Easily Diagnosed – Two teeth in alveolus, held by soft tissue Courtesy Dr. Cody Nelson 55 Bridal wire applied from #’s 9 – 11 to re-approximate bone Courtesy Dr. Cody Nelson 2008 Trampoline, 3 teeth pushed back w. alveolar fx. & splinting 2010 2 pulps died, why not 3? Frequency of Mandibular Fractures Deviation TO side of fx when opening 56 4-01 4 teeth Move Together Courtesy Dr. Steve Clark Alveolar Fx. – mixed-dentition removable/compos. splint 6 m post, good color, EPT? Courtesy Dr. Steve Clark 1 1/3 y post = AOK Note: Calcif. #26 canal Courtesy Dr. Steve Clark 57 3 year post-trauma Still asympt. Good color #26 calcif. Courtesy Dr. Steve Clark Cases: Concussion Fractures – crown – root Intrusion Subluxation Luxation Avulsion Resorption Ankylosis Bone fracture Pulp/PDL Regeneration Case Study Pulp Regeneration - need 1. 2. 3. 1.1 mm open apex Chemically debride necrotic pulp cells Place antibiotic mixture in canal Observe for signs of trouble Metronidazole Clindamycin Thibodeau…Trope JOE 2007;33:680-9. Minocycline Wang…Trope…Huang JOE 2010;36-56-63. 58 Current Thinking for Pulp Regen. ASAP: NaOCl debridement, instrumentation to min.110 file Dry Triple antibiotic paste (consider omitting tetracycline) 2 w. later: Saline irrigation of canal 0.04% NaOCl = highest concentration wo/ cell death) Induce bleeding from pulp stump (STEM CELLS) Preserve CLOT at mid root level Gently apply MTA over clot (Essner- George T-J. Huang SCID Mice Human roots – 6 mm long – implanted SQ canals reamed to 2 mm mm of an end plugged w/ MTA 5 mm wide, open canal space 1 Human stem cells planted in pulp turned into pulp, with working odontoblasts on dentin Huang et al. Tissue Eng Part A 2010 Feb;16:605-15. Tissue Engineering: Place PDL cells on Dry Tooth Dog: tooth extracted, PDL cells stripped and into culture medium (pulp extirpated), pulp left in dry isolation PDL cells grow and reproduce x 30 days PDL cells painted on root and replanted PDL reformed (control = ankylosis & resorption) Wang, JOE Feb. 2010 59 Cryopreservation Magnetic cryopreservation 73% preservation of cells (5 generations of normal reproduction after thawing) SLOW FREEZING IN A WEAK MAG. FIELD Lee JOE Aug 2010 Prognosis – Follow-ups Ins. Co. attorney wants legal release Test adjacent teeth Pulp cap is best bet Closed Apex Prognosis (Statistics mean nothing if you are the one) Pulp OK Pulp cap = 99% Concussion = 90% Subluxation = 75% - Calcif. Meta. 10% 20% Extrusion = 15% - Calcif. Meta. 60% 20% Lateral lux. = 10% - Calcif.Meta. 60% Alveolar fx. = 10% Intrusion = 0%??? Root Fx. = varies – 30% 100% 100% 60% Resorption / PDL Pulp Prognosis (open apex =10% better) 60 Follow-ups, AAE 2013 Guidelines Fx permanent Luxated teeth, bony fx. permanent teeth • 4w 2w • 6-8 w 4w • 4m 6-8 w • 6m 6m • 12 m 12m • Yearly x 5 y yearly x 5 y Avulsed perm. teeth Endo @ 7-10 d 2w 4w 3m 6m yearly x 5 y Splint (light)only if mobile, remove at 10 d-2 w Bony Fx and high root fx, splint (rigid)4 m. Gather Your Armamentarium Now Splint: material, bonding Suture Root therapy: 2.4% sodium fluoride, Emdo-Gain, GEM21 Canal therapy: Ca(OH)2, other disinfectant, c/s, bisphosphonate Triple Antibiotic Paste Metronidazole, S u m m a r y Clindamycin, Minocycline (?) Determine direction/ amount of force C-spine x-rays, etc. Tetanus Antibiotic X-ray/palpate lip/cheek/tongue Where is the broken piece ? Lung x-ray x-rays of roots Multiple Wiggle one tooth / Do others move ? Occlusion Don’t Forget the Soft diet Whole Body ! Follow-up 61 Summary What was the direction and concentration of force? Did a fracture dissipate some force? Think at the microscope level What are the cells doing? Can the cementum reform? What is the healing timeline? PDL mends in 6-8w. What is the blood supply like? Disclaimer These are current Not guarantees guidelines Guidelines are NOT Absolutes 62