cryo preservation catalog rev J 1:Cryo preservation catalog 1

Cryopreservation Equipment
Storage and Transport Systems for Biological Materials
MVE Biological Systems
Excellence & Innovation
Chart-MVE is the world’s leading manufacturer of vacuum
insulated products and cryogenic systems. More than forty years
ago, we set the standard for storage of biological materials at low
temperatures. Today, we continue to exceed these standards. Industries from around the world look to Chart-MVE for excellence
and innovation. Our solutions empower industries to better utilize
cryogenic technology. In this manner, Chart-MVE continues to
make a vital contribution in today’s biomedical industry.
Chart-MVE has the solution for all of your cryogenic storage
needs. We offer the broadest range of storage capacities for your
biological products, with the most advanced vacuum technology
available today.
Chart-MVE is the market leader in the manufacturing of Bulk
Storage, Liquid Cylinder and Vacuum Insulated Pipe products.
Chart-MVE applied this knowledge to the development and creation of “Turn Key” liquid nitrogen supply systems that can provide your freezer with the most economical use of liquid nitrogen
and the best return on your storage investment.
Every Chart-MVE freezer is designed for optimum vacuum performance for the duration of its use. Chart-MVE freezers are engineered to hold and maintain specific temperatures, whether
samples are in liquid or vapor. Chart-MVE offers the widest
range of storage capacities and storage options (from -125°C to
-196°C) to suit your biological product needs.
By choosing Chart-MVE, you are installing a secure and viable
environment, free of the noise and heat created by mechanical refrigeration systems. Chart-MVE products meet worldwide standards of excellence such as CE, MDD, UL, IATA, TGA, and ISO
9001. Factory tested to ensure reliability in the field, Chart-MVE
vessels are backed by one of the strongest and longest warranties
in the industry.
Inventory Management &
Environmental Monitoring
Chart-MVE also offers its customers Cryobyte LSTM, a complete
software solution for managing the storage and monitoring of
their biorepositories. Cryobyte LSTM is the only product that
combines inventory management and real-time environmental
monitoring into one complete package. Additional features include remotely reporting and responding to alarm events, which
will meet their Quality System requirements for a comprehensive
audit trail and electronic data system security. Cryobyte LSTM
Software is compliant with 21 CFR11.
Service to Match Your Expectations
• Worldwide network of qualified and certified distributors.
• Each distributor is factory trained in sales and service to
provide you with the expert assistance you deserve.
Product Warranties
• Standard two (2) year warranty on
all equipment.
• Three (3) year vacuum warranty
on CryoSystem Series, Doble Series
and Vapor Shippers.
• Five (5) year vacuum warranty on
Stainless Steel Freezers, XC/SC
Aluminum Units, and LAB units.
• Static evaporation rate and static
holding times are nominal. Actual
rate and holding time will be affected
by the nature of container use, atmospheric conditions, and manufacturing
tolerances.
2 Cryopreservation Catalog
Cryopreservation
All biological materials deteriorate over time–this is an unavoidable physical phenomenon. When the need to study and/or store
biological materials arises, a long-term reliable storage solution
is needed; cryopreservation is the answer. When exploring
cryopreservation as a storage solution, many factors must be
considered, including, but not limited to: Critical Temperature,
Storage Phase, and Capacity. MVE offers a complete line of
storage solutions in liquid or vapor, with temperatures ranging
from -125°C to -190°C.
Understanding the materials to be stored is vital to determining
the critical temperature. Most biological materials must be stored
below the Glass Transition of Water (Tg) before long term degradation is minimized. The value of Tg is most commonly agreed
to be between -130°C and -135°C. Storage above this temperature will result in poor long term viability of samples. Storage
conditions that transition above and below this value will accelerate degradation of samples. Knowing this, one can make the
conclusion that colder is better. All MVE freezers are created to
maintain the coldest and most consistent temperature in their
designed operating ranges. Many models can maintain near
liquid nitrogen temperature in the warmest part of the freezer,
minimizing transient temperature conditions.
Determining the phase of storage is nearly as critical as determining the proper storage temperature. Storing in liquid phase
provides the longest possible hold time and coldest possible
temperature. Vapor storage minimizes the possibility of cross
contamination and exposure of samples to liquid nitrogen. MVE
provides a complete line of freezers that can meet any storage
solution in liquid or vapor.
Selecting the proper size freezer is important to ensuring the long
term efficiency and cost effectiveness of the repository. MVE
offers the widest, most complete product line in the world and
can meet the needs of the small research laboratory as well as the
largest long term repository. Your local MVE distributor can help
you select a freezer that is large enough to meet your current
needs and provide room for growth.
Recommended maximum temperature for storage of biological samples.
MATERIAL TO BE
STORED
Algae
Blood
Cells:
Animals
/Human
Plant
Embryos
Fungi:
Mycelium
Hybridomas
Phage:
Libraries
Protozoa
Viruses: Animal
In Cells
VOLUME
CONTAINER
Cryovial
Cryovial/Blood Bag
INVENTORY
CONFIGURATION
Boxes or canes
Boxes or canes/bag rack
CRITICAL
TEMPERATURE
-150°C
-150°C
0.5 - 1.0 mL
0.5 - 500 mL
0.5 - 1.0 mL
0.5 - 1.0 mL
Cryovial
Cryovial
Straw
Boxes or canes
Boxes or canes
Canes
-150°C
-150°C
-150°C
0.5 - 1.0 mL
0.5 - 1.0 mL
Cryovial
Cryovial
Boxes or canes
Boxes or canes
-150°C
-150°C
0.5 - 1.0 mL
0.5 - 1.0 mL
Cryovial
Cryovial
Boxes or canes
Boxes or canes
-150°C
-150°C
0.5 - 1.0 mL
Cryovial
Boxes or canes
-150°C
Source: F. Simeone, American Type Culture Collection, Manassas, VA
3
Product Overview:
CryoBiological
Product Selector Guide
Do you need to
store in vapor?
NO
YES
Do you require
-190°C under
the lid?
YES
Choose from
the
NO
Do you want YES
easy access to
the samples and
the lowest LN2
consumption?
MVE High
Efficiency/
Vapor Series
NO
Do you need to
store more than
6000 vials or YES
straws?
Choose
from the
NO
MVE Series
A Offset neck design to maintain -150°C or -190°C in
vapor storage and provide low liquid nitrogen
consumption
B Optimized lid design for enhanced durability
Do you need to
store more than
1500 vials?
NO
NO
C Rotating interior tray provides easy access to cryobiological samples
D Low Maintenance, all-stainless steel construction
E Annular filling lines reduce frost and ice formation near
lid
YES
Are you using
square storage
boxes?
YES
NO
Choose
from the
Choose from the
F Durable casters
G Two-level folding step on 1500 and 1800 series models
provides lowest liftover height
H Advanced TEC 3000 controller
4 Cryopreservation Catalog
MVE
CryoSystem
Series
MVE
SC/XC
Series
TEC 3000
The TEC 3000 employs a variety of advanced features that enable the controller to monitor
and control the environment inside a freezer with a high level of precision.
Features/Options:
• Liquid Nitrogen Level Measurement
• Automatic Liquid Nitrogen Level Control
• Two Channel Temperature Measurement
• Multiple-use Adjustable Alarms
• Adjustable Security / Password System
• One Fill All Capability (Sequential or Simultaneous)
• Timed Filling
• Battery Backup (Optional)
• Gas Bypass (Optional)
Technical Specifications:
• Level Measurement
- Sensor Type - Dual Port Pressure Transducer Measurement
Accuracy +/- .5 in; +/- 13 mm (typical)
- Liquid Usage Feature
- Two Point Calibration Feature
• Level Control
- Range 3–48” (76-122 mm)
- Control Output - (Fill Solenoid Valve)
- 24 VDC, 1.0 amp (max)
• Temperature Measurement
-Two Sensors, Platinum RTD - Two wire element
• Accuracy +/-2.0°C Full Scale
• Altitude Compensation For Accuracy
• Full Range Calibration Feature
• Probe Heater For High Temp Alarm Testing
• Front Panel Display
- Backlit LCD Readout, 4 row x 20 character
- Level Display - in, mm, %
- Temperature Display - °C, °F, or K
• Standard Alarms
- Alarm Conditions
• Low Level Alarm
• High Level Alarm
• Low Temperature (Probe A & B)
• High Temperature (Probe A & B)
• Fill Time Alarm
• Power Failure (remote only)
• Lid Open Alarm
• Usage Warning and Alarm
• Temperature Calibration Alarm (Probe A & B)
• Optional Alarms
- Bypass Sensor Failure
- Bypass Time
- Bypass Sensor Calibration
- Power Failure (audible, visual and remote alarms)
- Low Battery Voltage
• Alarm Output
- Both Visual and Audible Alarms
- One Global Remote Alarm Relay
- Four Discrete Remote Contacts
• Temp A High
• Low Level
• High Level
• Low Battery (optional when equipped with
battery backup)
• Controller Features
- Communication Interface: Serial Communication
RS485/ASCII/MODBUS
- Memory: Stores time and date stamped information
on the controller’s 30,000 most recent events
5
MVE High Efficiency/Vapor Series
There is a critical temperature for most biological samples that are cryopreserved. This critical temperature is known as the Glass Transition Temperature (Tg) of water, which is widely accepted as being in the order of -130° to -135°C. The long-term viability of frozen
samples can be seriously compromised if stored above this temperature range. Further, if they experience several transitions through
this range in either thermal direction, additional deterioration may occur. It is important that the LN2 freezer
maintain a lower temperature, even during filling and sample retrieval cycles. This is much more likely to be
achieved if the freezer maintains a temperature of -190°C than if the system is at or near the critical temperature at
Optional Step for
800 Series
Product
Specifications
815P-150
818P-150
819P-150
1536P-150
1539P-150
18200
12
4
14
19500
12
4
15
36400
24
16
13
39200
24
16
14
370
420
463
756
797
52
55
55
133
133
12.5 (317)
30.7 (781)
28.8 (731)
53.3 (1353)
32 (813)
33.19x32 (843x813)
495 (225)
1168 (530)
12.5 (317)
34.5 (877)
28.8 (731)
57 (1449)
32 (813)
33.19x32 (843x813)
515 (234)
1340 (608)
17.5 (445)
28.8 (730)
38.5 (978)
54.9 (1393)
42 (1066)
43.6x54.1 (1107x1172)
7.9 (202)
690 (313)
2037 (924)
17.5 (44)
30.8 (781)
38.5 (978)
56.8 (1445)
42 (1066)
42x46.1 (1066x117)
7.9 (202)
720 (327)
2140 (971)
819P-150
Total Bags/ No.
Bags Frame Frames
1536P-150
Total Bags/ No.
Bags Frame Frames
1539P-150
Total Bags/ No.
Bags Frame Frames
MAXIMUM STORAGE CAPACITY
1.2 & 2 mL Vials (Internally Threaded) 15600
Number of Racks 100 cell boxes
12
Number of Racks 25 cell boxes
4
Number of Stages per Rack
12
PERFORMANCE
LN2 Capacity L
LN2 Capacity Under
Platform Vapor Storage L
UNIT DIMENSIONS
Neck Opening in. (mm)
12.5 (317)
Usable Internal Height in. (mm) 26.6 (676)
Inner Diameter in. (mm)
28.8 (731)
Overall Height in. (mm)
49 (1245)
Outer Diameter in. (mm)
32 (813)
Footprint in. (mm)
33.19x32 (843x813)
Depth of Extended Step in. (mm)
Weight Empty lb. (kg)
475 (215)
Weight Full lb. (kg)
1134 (514)
Blood Bag Capacities
Unit
815P-150
Total Bags/ No.
Bags Frame Frames
818P-150
Total Bags/ No.
Bags Frame Frames
791 OS/U (25 mL)
1224
6
204
1632
8
204
-
-
-
3080
7
440
3064
8
383
4R9951 (50 mL)
768
6
128
896
7
128
1024
8
128
1488
6
248
1736
7
248
4R9953 (250 mL)
416
4
104
416
4
104
520
5
104
812
4
203
812
4
203
4R9955 (500 mL)
304
4
76
304
4
76
380
5
76
608
4
152
608
4
152
DF200 (200 mL)
236
4
59
-
-
-
295
5
59
496
4
124
496
4
124
DF700 (700 mL)
-
-
-
-
-
-
-
-
-
256
4
64
256
4
64
TWO Year Standard Warranty • FIVE Year Vacuum Warranty
6 Cryopreservation Catalog
-150 & -190
normal equilibrium. Chart-MVE’s approach to this problem was to
improve the fundamental design of freezers used in vapor phase and
to design and build a nitrogen vapor freezer which ensures stability
at -190°C.
MVE 1879P-150
MVE 1892P-150
MVE 815P-190
MVE 1536P-190
MVE 1879P-190
79950
54
30
13
92250
54
30
15
15600
12
4
12
36400
24
16
13
79950
54
30
13
1612
1829
370
756
1672
260
296
52
133
296
25 (635)
28.8 (732)
56.3 (1429)
60.6 (1539)
60 (1524)
60x64.1 (1524x1629)
15.2 (385)
1585 (719)
4458 (2022)
25 (635)
34.5 (876)
56 (1422)
67.1 (1704)
60 (1524)
60x64.1 (1524x1629)
15.2 (385)
1545 (701)
4803 (2179)
12.5 (317)
26.5 (673)
28.8 (731)
49 (1245)
32 (813)
32x33.2 (813x843)
475 (215)
1134 (514)
17.5 (445)
28.8 (730)
38.5 (978)
54.9 (1393)
42 (1066)
46.1x42 (1172x1066)
7.94 (202)
690 (313)
2037 (924)
25 (635)
29.5 (749)
56 (1422)
62.1 (1577)
60 (1524)
64.1x60 (1629x1524)
15.2 (385)
1606 (728)
4585 (2080)
Total
Bags
1879P-150
Bags/ No.
Frame Frames
MVE 1892P-150
Total Bags/
No.
Bags Frame Frames
MVE 815P-190
Total
Bags/ No.
Bags Frame Frames
MVE 1536P-190
Total Bags/
No.
Bags Frame Frames
MVE 1879P-190
Total Bags/ No.
Bags Frame Frames
5866
7
838
6704
8
838
1224
6
204
3080
7
440
5866
7
838
2952
6
492
3936
8
492
768
6
128
1488
6
248
2952
6
492
1584
4
396
1980
5
396
416
4
104
812
4
203
1584
4
396
1104
4
276
1380
5
276
304
4
76
608
4
152
1104
4
276
960
4
240
1200
5
240
236
4
59
496
4
124
960
4
240
504
4
126
630
5
126
-
-
-
256
4
64
504
4
126
• Units available which conform to MDD 93/42/EEC, the Medical Device Directive for the EU.
7
MVE High Efficiency/Vapor Series
Product
Specifications
MVE 1539R-150
MVE 1542R-150
MVE 1542R-190
39000
42000
42000
Number of Racks 100 cell boxes
26
26
26
Number of Racks 25 cell boxes
16
16
16
Number of Stages per Rack
13
14
14
756
797
797
133
113
113
Neck Opening in. (mm)
17.5 (445)
17.5 (445)
17.5 (445)
Usable Internal Height in. (mm)
29.3 (745)
31.3 (745)
30.8 (781)
MAXIMUM STORAGE CAPACITY
1.2 & 2 mL Vials (Internally Threaded)
PERFORMANCE
LN2 Capacity (L)
LN2 Capacity Under Platform
Vapor Storage (L)
UNIT DIMENSIONS
Inner Diameter in. (mm)
38.7 (983)
38.7 (983)
38.7 (983)
Overall Height in. (mm)
54.9 (1393)
56.9 (1445)
56.9 (1445)
42 (1066)
42 (1066)
42 (1066)
43.6x46.2 (1107x1172)
43.6x46.14 (1107x1172)
43.6x46.1 (1107x1172)
Outer Diameter in. (mm)
Footprint in. (mm)
Depth of Extended Step in. (mm)
7.9 (202)
7.9 (202)
7.9 (202)
Weight Empty lb. (kg)
690 (313)
720 (327)
720 (327)
Weight Full lb. (kg)
2037 (924)
2140 (971)
2140 (971)
Blood Bag Capacities
Unit
MVE 1539R-150
Total
Bags/
No.
Bags
Frame Frames
MVE 1542R-150
Total
Bags/
No.
Bags
Frame Frames
MVE 1542R-190
Total
Bags/
No.
Bags
Frame
Frames
791 OS/U (25 mL)
2786
7
398
3184
8
398
3184
8
398
4R9951 (50 mL)
1446
6
241
1687
7
241
1687
7
241
4R9953 (250 mL)
768
4
192
960
5
192
960
5
192
4R9955 (500 mL)
576
4
144
720
5
144
720
5
144
DF200 (200 mL)
488
4
122
610
5
122
610
5
122
DF700 (700 mL)
264
4
66
330
5
66
330
5
66
TWO Year Standard Warranty • FIVE Year Vacuum Warranty
• Units available which conform to MDD 93/42/EEC, the Medical Device Directive for the EU.
8 Cryopreservation Catalog
R-150 & R-190
MVE 1881R-150
MVE 1881R-190
MVE 1894R-150
MVE 1894R-190
81900
81900
94500
94500
60
60
60
60
12
12
12
12
13
13
15
15
1612
1745
1770
1770
260
318
295
295
25 (635)
25 (635)
25 (635)
25 (635)
29.2 (741)
29.2 (741)
34.2 (868)
34.2 (868)
56.3 (1429)
54.8 (1391)
54.8 (1391)
54.8 (1391)
60.6 (1539)
61.3 (1556)
66.3 (1683)
66.3 (1683)
60 (1524)
60 (1524)
60 (1524)
60 (1524)
60x64.1 (1524x1629)
60x64.1 (1524x1629)
60x64.1 (1524x1629)
60x64.1 (1524x1629)
15.2 (385)
15.2 (385)
15.2 (385)
15.2 (385)
1606 (728)
1721 (781)
1721 (781)
1721 (781)
4479 (2032)
4830 (2192)
4875 (2211)
4875 (2211)
MVE 1881R-150
Total Bags/
No.
Bags Frame Frames
MVE 1881R-190
Total Bags/
No.
Bags Frame Frames
MVE 1894R-150
Total
Bags/
No.
Bags Frame Frames
MVE 1894R-190
Total
Bags/
No.
Bags
Frame Frames
5628
7
804
5628
7
804
6432
8
804
6432
8
804
2940
6
490
2940
6
490
3920
8
490
3920
8
490
1608
4
402
1608
4
402
2010
5
402
2010
5
402
1240
4
310
1240
4
310
1550
5
310
1550
5
310
984
4
246
984
4
246
1230
5
246
1230
5
246
544
4
136
544
4
136
680
5
136
680
5
136
TWO Year Standard Warranty • FIVE Year Vacuum Warranty
• Units available which conform to MDD 93/42/EEC, the Medical Device Directive for the EU.
9
MVE Series
MVE Cryopreservation Systems are designed to
be used for either vapor or liquid storage. A wide
neck opening and stainless steel construction
provide the most durable environment for your
biological samples. With advanced features and
storage from 3,200 to 39,000 vials, the MVE
series is the choice of laboratories worldwide.
The MVE Series freezers are designed primarily for liquid phase storage. If vapor phase storage is required, ask your distributor about the
vapor storage accessory package.
Product Specifications
MVE 204*
MVE 205
MVE 510
3200
4
4
-
5200
4
4
13
10400
7
4
11
13
65
95
166
16 (406)
19.7 (502)
30.8 (784)
18 (457)
16 (406)
19.4x18.9 (492x479)
79 (36)
195 (88)
16 (406)
28.9 (735)
41.6 (1059)
20.4x18.5 (518x470)
16 (406)
20.4x18.5 (518x470)
195 (88)
365 (166)
20.7 (527)
30 (762)
46.7 (1185)
30.6x29.7 (778x754)
20.7 (527)
29.1x30.6 (740x778)
281 (127)
577 (262)
MAXIMUM STORAGE CAPACITY
Number of 1.2 & 2.0 mL vials in racks
Number of racks 100 vials
Number of racks 25 vials
Total number of racks
Number of Stages per Rack
PERFORMANCE
Liquid nitrogen capacity L
UNIT DIMENSIONS
Neck opening in (mm)
Usable height in (mm)
Overall height in (mm)
Outside diameter in (mm)
Internal diameter in (mm)
Footprint in (mm)
Weight empty lb. (kg)
Weight full lb. (kg)
Blood Bag Capacities (Liquid Phase Storage)
Unit
791 OS/U (25 mL)
Total
Bags
MVE 204*
Bags/
Frame
No.
Frames
Total
Bags
-
-
-
539
MVE 205
Bags/
No.
Frame Frames
7
77
Total
Bags
MVE 510
Bags/
Frame
No.
Frames
882
7
126
4R9951 (50 mL)
-
-
-
228
6
38
420
6
70
4R9953 (250 mL)
-
-
-
128
4
32
224
4
56
4R9955 (500 mL)
-
-
-
96
4
24
160
4
40
DF200 (200 mL)
-
-
-
80
4
20
128
4
32
DF700 (700 mL)
-
-
-
40
4
10
68
4
17
*Number of SUC-1 Canisters is 22
10 Cryopreservation Catalog
TWO Year Standard Warranty • FIVE Year Vacuum Warranty
MVE 616
MVE 1426
16900
12
4
16
13
26650
18
10
28
13
39000
28
8
36
13
240
388
673
25.1 (638)
29.5 (749)
45.8 (1161)
33.5x34.6 (852x878)
25.13 (638)
33.8x33.5 (859x852)
320 (145)
748 (339)
31.75 (806)
29.3 (745)
42.4 (1076)
33.8x41.6 (858x1056)
31.75 (806)
41.6x40 (1056x1017)
490 (222)
1181 (536)
39.4 (1002)
33.6 (854)
54 (1372)
46.1x48.3 (1172x1225)
39.4 (1002)
48.9x46.8 (1243x1187)
750 (341)
1950 (885)
Total
Bags
MVE 616
Bags/
Frame
No.
Frames
Total
Bags
1372
7
196
-
MVE 1839
MVE 1426
Bags/
No.
Frame
Frames
-
-
Total
Bags
MVE 1839
Bags/
No.
Frame
Frames
3968
8
496
612
6
102
924
6
154
1856
8
232
336
4
84
512
4
128
1010
5
202
248
4
62
424
4
106
770
5
154
200
4
50
336
4
84
854
7
122
116
4
29
168
4
42
532
7
76
Units available which conform to MDD 93/42/EEC, the Medical Device Directive for the EU.
11
MVE Stock Series
MVE Stock Series tanks are primarily designed for storage of
either vials or straws on canes in liquid nitrogen. The tanks are
built for long life, durability in service and ergonomic sample
retrieval, all of vital importance for this type of storage environment. Dual lids on the MVE 1318 aid in sample removal while
retaining critical temperatures inside the storage area. The rotating sample tray in the 1842P-150 allows for maximum storage
space and easy access. All MVE Stock units are built with an
emphasis on sample security and the ability to provide safe
long-term storage for your valuable samples.
Product Specifications
Model
MAXIMUM STORAGE CAPACITY
MVE 103
MVE 808
Number of 1.2 & 2.0 mL vials in racks
-
11700
Number of racks 100 vials
-
12
Number of racks 25 vials
-
4
Total number of racks
-
16
22
61
Number of 1.2 ml vials on canes
3168
8784
Number of 2.0 ml vials on canes
1760
4880
Number of 1/2 cc straws 10/cane
6820
18910
39
230
16 (406)
25 (634)
Number of SUC-1 canisters (2.5” x 2.5” x 11”)
PERFORMANCE
Liquid nitrogen capacity L
UNIT DIMENSIONS
Neck Opening in (mm)
Usable height in (mm)
12 (305)
22 (558)
Overall height in (mm)
16.4 (415)
42.8 (1088)
Outside diameter in (mm)
18 (457)
31 (787)
Internal diameter in (mm)
16 (406)
28.3 (720)
19.4x18.9 (492x479)
35.2x31 (893x787)
-
-
Footprint in (mm)
Depth of Extended Step in. (mm)
Weight empty lb. (kg)
48 (22)
250 (114)
Weight full lb. (kg)
117 (53)
660 (300)
TWO Year Standard Warranty • FIVE Year Vacuum Warranty
12 Cryopreservation Catalog
MVE 816P-2T-190
MVE 1318
MVE 1842P-150
MVE 1877P-2T-150
-
20800
-
-
-
24
-
-
-
8
-
-
-
32
-
-
115
129
294
539
16560
18576
42336
77616
9200
10320
23520
43120
35650
39990
91140
167090
381
482
915
1400
12.5 (317)
35.5 (901)
25 (635)
25 (635)
13 (330) per level
18.8 (479)
13 (332)
13 (330) per tray
50 (1271)
47 (1193)
44.3 (1127)
58.2 (1479)
32 (813)
42 (1067)
60 (1524)
60 (1524)
28.7 (728) top tray 27.7 (702) bottom
39.6 (1007)
56.25 (1429)
56.25 (1429)
32x33.2 (813x843)
42x42 (1067x1067)
60x60 (1524x1524)
64.2x60 (1629x1524)
-
-
-
15.1 (385)
475 (215) est.
469 (213)
1167 (530)
1600 (726)
1155 (524) est.
1328 (602)
2798 (1270)
4094 (1857)
• Units available which conform to MDD 93/42/EEC, the Medical Device Directive for the EU.
13
MVE Cabinet Series
The MVE 600 and 1400 Cryopreservation Systems
are designed to provide reliable storage of biological
products in liquid or vapor*. The units are upgraded
with improved ergonomics and easier sample access.
In addition, the cabinets are constructed from aluminum, with stainless steel top decks. With vial storage capacities ranging from 16900 to 26650,
low-maintenance design and the TEC 3000 controller,
the MVE Cabinet Series are world-class, wide neck
freezers.
* The MVE 600/1400 Series Freezers are designed primarily for
liquid phase storage. If vapor phase storage is required, ask your
distributor about the available vapor phase storage accessory
package.
Product Specifications
Model
MAXIMUM STORAGE CAPACITY
Number of 1.2 & 2.0 mL
vials in racks
Number of racks 100 vials
Number of racks 25 vials
Number of Stages per Rack
Total vial capacity
PERFORMANCE
Liquid nitrogen capacity L
UNIT DIMENSIONS
Neck Opening in (mm)
Usable height in (mm)
Overall height in (mm)
Outside diameter in (mm)
Internal diameter in (mm)
Footprint in (mm)
Weight empty lb. (kg)
Weight full lb. (kg)
MVE 616C
MVE 1426C
16900
12
4
13
16900
26650
18
10
13
26650
243
388
25.1 (638)
30 (762)
41.4 (1051)
35.1x28 (892x711)
25.1 (638)
35.1x28 (892x711)
352 (160)
785 (356)
31.8 (806)
29.9 (759)
42.3 (1075)
41.1x34.8 (1044x883)
31.8 (806)
41.1x34.8 (1044x883)
530 (240)
1198 (543)
Blood Bag Capacities (Liquid Phase Storage)
Unit
Total Bags
MVE 616C
Bags/Frame No. Frames
MVE 1426C
Total Bags Bags/Frame No. Frames
791 OS/U (25 mL)
1372
7
196
-
-
-
4R9951 (50 mL)
4R9953 (250 mL)
4R9955 (500 mL)
DF200 (200 mL)
DF700 (700 mL)
612
336
248
200
116
6
4
4
4
4
102
84
62
50
29
924
512
424
336
168
6
4
4
4
4
154
128
106
84
42
TWO Year Standard Warranty • FIVE Year Vacuum Warranty
Units available which conform to MDD 93/42/EEC, the Medical Device Directive for the EU.
14 Cryopreservation Catalog
MVE Cryo Cart
Product Specifications
UNIT CAPACITIES
LN2 Capacity To Top of Platform L
53
UNIT DIMENSIONS
MVE Cryo Carts are designed for the safe loading of biological
samples into canes, boxes, racks or frames. When used as a
portable workbench with the lid removed, the unit will provide a
safe and controlled environment for your samples for up to ten
hours.
Overall Length in (mm)
51.69 (1313)
Overall Width in (mm)
17.56 (192)
Overall Height in (mm)
38.875 (987)
Lift Overall Height in (mm)
36.31 (922)
Inside Length in (mm)
41 (1041)
Inside Width in (mm)
13.25 (337)
Inside Depth in (mm)
15.44 (392)
Platform Height in (mm)
6 (152)
Footprint in (mm)
17.56x51.69 (446x1313)
Weight Empty lb. (kg)
241 (109)
Weight w/LN2 Filled To
Top Of Platform lb. (kg)
356 (161)
Approximate Hold Time With Lid On hrs
18
Number of Racks
2
The MVE Cryo Cart is ideal for transporting large quantities of
samples from one tank to another within the same facility. These
high-efficiency carts are the safest and most convenient way to
protect the viability of your samples!
Features:
• Approximate hold time of 18 hours with lid in place
• Omega temperature monitor with Type-T Thermocouple
• Traceable calibration certificate with RS232 PC interface
• LN2 transfer hose connection with ball and relief
valve
Recommended Accessories:
• Square Stainless or Aluminum Racks
• Cardboard Boxes
• Plastic Boxes
• Canes and Protectors
• Cryogenic Gloves / Apron
One (1) Year Standard Warranty
15
Product Overview: Aluminum
Doble 20
SC 20
A
B
C
D
E
F
G
H
I
J
A Durable, tamper-proof lid design
F Advanced chemical vacuum retention system
B Locking tab
G Insulation to provide maximum thermal performance
C Easy maintenance lid design
H Superior strength, lightweight aluminum construction
D Color-coded canister/lid numbering system
I
Spider design for easy retrieval and insertion of
product canisters
J
Hydrophobic liquid nitrogen absorbent system
E High strength neck tube reduces liquid nitrogen loss
16 Cryopreservation Catalog
MVE CryoSystem Series
The MVE CryoSystem 750, 2000, 4000 and 6000 combine the benefits of low nitrogen consumption with mid-range vial capacity to
meet the diverse needs of today’s professionals worldwide. The lightweight and low-space demands of these containers make them the
most economical units in their class. Chart-MVE cryogenic vessels are performance leaders through innovation, super insulation and
vacuum technology.
Product Specifications
Model
CryoSystem
750
CryoSystem
2000
CryoSystem
4000
CryoSystem
6000
6
750
5
4
2000
5
4
4000
10
6
6000
10
47.4
0.39
47
76
61
.85
51
38
121
.99
111
70
175
.99
165
104
8.5 (216)
38 (965)
22 (559)
81 (36.7)
300 (136)
8.5 (216)
37.75 (959)
26 (665)
103 (46.7)
425 (193)
MAXIMUM STORAGE CAPACITY
Number of Racks
Number of 1.2 & 2.0 ml vials (100/Box)
Number of 1.2 & 2.0 ml vials (25/Box)
Boxes Per Rack
PERFORMANCE
Liquid nitrogen capacity L
Static Evaporation Rate L/day
Working Volume L
Normal Working Duration days
UNIT DIMENSIONS
Neck opening in (mm)
5 (127)
8.5 (216)
Overall height in (mm)
26.5 (673)
27.25 (692)
Outside diameter in (mm)
20 (508)
22 (559)
Weight empty lb. (kg)
42 (19)
58 (26.3)
Weight full lb. (kg)
126 (57)
182 (82.5)
THREE Year Vacuum Warranty
Conforms to MDD 93/42/EEC, the Medical Device Directive for the EU.
* Static evaporation rate and static holding times are nominal. Actual rate and holding time will be affected by the nature of container use, atmospheric conditions, and manufacturing tolerances.
** Normal Working Duration is an arbitrary reference, to estimate container performance under normal operating conditions. Actual working time may vary due to current atmospheric conditions, container history, manufacturing tolerances and any individual patterns of use.
Roller Base
Measuring Stick
Gloves
Vapor Inserts
17
MVE Lab Series
The Lab Series cryogenic liquid dewars get their name from their acceptance in laboratories and medical facilities worldwide. These
high-efficiency, super insulated dewars are the most convenient, economical way to store and dispense liquid nitrogen. Many lab units
can be fitted with pouring spouts, pressurized dispensing devices, or dippers to aid in the transfer of liquid nitrogen.
Product
Specifications
MODEL
LAB 4
LAB 5
LAB 10
LAB 20
4
5
10
20
0.19
0.15
0.18
0.18
Neck opening in (mm)
1.4 (35.5)
2.18 (56)
2.18 (56)
2.18 (51)
Usable height in (mm)
7.8 (198)
10.5 (266)
13.5 (343)
13.7 (348)
Overall height in (mm)
16.8 (426)
18.2 (462)
21.5 (546)
24.5 (622)
Outside diameter in (mm)
7.3 (185)
8.8 (222)
10.3 (260)
14.5 (368)
Internal diameter in (mm)
5.5 (139)
6.5 (165)
8.3 (210)
11.4 (289)
Weight empty lb. (kg)
6 (2.7)
8 (4)
12 (5.4)
19 (9)
Weight full lb. (kg)
13 (6)
17 (8)
31 (14)
55 (25)
Net Capacity L
PERFORMANCE
Static Evaporation Rate L/day
UNIT DIMENSIONS
Accessories
Manual Discharge Device
18 Cryopreservation Catalog
Spare Plug
Cork
Pouring Spout
LAB 30
LAB 50
SS 1.5L
SS 2.5L
SS 5L
32
50
1.5
2.5
5
0.22
0.49
N/A
N/A
N/A
2.5 (64)
2.5 (64)
5.9 (149)
5.9 (149)
6 (152)
14.9 (378)
22 (559)
3.8 (86)
5.6 (143)
14 (356)
24 (610)
30.5 (775)
9.5 (242)
11.8 (300)
16.5 (419)
17 (432)
17 (432)
8 (203)
8 (203)
8 (203)
14 (356)
14 (356)
6 (152)
6 (152)
6 (152)
25 (11.4)
31 (14)
6 (2.7)
8 (3.6)
11 (5)
82 (37.2)
120 (54.4)
8.6 (3.9)
12.5 (5.7)
20 (9)
FIVE Year Vacuum Warranty
Conforms to MDD 93/42/EEC, the Medical Device Directive for the EU.
Gloves
Rigid Dipper
Swivel Dipper
Roller Base
19
MVE SC Series
MVE offers the widest range of compact aluminum storage tanks available on the market today. Over the past 50 years, our product
designs have improved through end-user input and evolved into a unique selection of units. The SC Series is designed for the user who
has small capacity needs, but requires long-term storage and low liquid nitrogen consumption in a convenient lightweight package.
Product Specifications
MODEL
MAX. STORAGE CAPACITY
SC 3/3
SC 8/5
SC 11/7
Number of canisters
No. of 1/2 cc straws 10/cane
No. of 1/2 cc straws 1 Level Bulk
No. of 1.2 & 2.0 ml vials 5/cane
6
1122
-
6
1122
-
6
720
1122
210
3.6
0.13
17
8.4
0.15
35
11
0.16
43
2.18 (55.4)
16 (406)
8.7 (222)
5 (127)
1.65 (41.9)
8 (3.6)
14.4 (65)
2.18 (55.4)
18.5 (470)
10.2 (260)
5 (127)
1.65 (41.9)
12 (5.3)
27 (12.1)
2.18 (55.4)
21.6 (549)
10.2 (260)
11 (279)
1.65 (41.9)
17 (7.7)
36.6 (16.6)
PERFORMANCE
Liquid nitrogen capacity L
Static evaporation rate L/day*
Normal Working Duration day**
UNIT DIMENSIONS
Neck opening in (mm)
Overall height in (mm)
Outside diameter in (mm)
Canister height in (mm)
Canister diameter in (mm)
Weight empty lb. (kg)
Weight full lb. (kg)
FIVE Year Vacuum Warranty
Conforms to MDD 93/42/EEC, the Medical Device Directive for the EU.
Accessories
Cryo Sleeves
20 Cryopreservation Catalog
Canes
Cork
Roller Base
*
SC 16/11
SC Millennium 20
SC 20/20
SC 33/26
SC 36/32
9
1098
-
6
540
780
150
6
540
780
150
6
540
780
150
6
540
780
150
16.4
0.14
74
20.5
.095
135
20.5
0.09
142
33
0.13
182
36.5
0.10
224
2.18 (55.4)
17.5 (444)
17.2 (438)
5 (127)
1.5 (38)
14 (6.4)
43 (19.6)
2.18 (55.4)
25.7 (652)
14.5 (368)
11 (279)
1.5 (38)
23 (10.5)
59.5 (27)
2 (51)
25.7 (652)
14.5 (368)
11 (279)
1.5 (38)
26 (11.8)
62.5 (28.3)
2 (51)
25.9 (657)
18.2 (464)
11 (279)
1.5 (38)
34 (15.4)
93.4 (42.4)
2 (51)
27.2 (690)
18.2 (464)
11 (279)
1.5 (38)
34 (15.4)
100 (44.8)
Static evaporation rate and static holding time are nominal. Actual rate and holding time will be affected by the nature of container use, atmospheric conditions, and manufacturing tolerances.
** Normal Working Duration is an arbitrary reference, to estimate container performance under normal operating conditions. Actual working time may vary due to current atmospheric conditions, container history, manufacturing tolerances and
any individual patterns of use.
Phase Separators
Measuring Stick
Gloves
Vapor Inserts
21
MVE XC Series
MVE XC Series tanks have capacities ranging from 700-5000 straws and 150-1000 vials. Manufactured to a world class level of
excellence and backed by a 5 year vacuum warranty, these durable, lightweight units can be relied on to perform in the most
demanding of environments. The XC Series is designed for the user who requires large capacity storage and low liquid nitrogen
consumption in a convenient lightweight package.
Product
Specifications
MODEL
MAX. STORAGE CAPACITY
Number of canisters
No. of 1/2 cc straws 10/cane
No. of 1/2 cc straws 1 Level Bulk
No. of 1.2 & 2.0 ml vials 5/cane
No. of 1.2 & 2.0 ml vials 25/box
XC
Millennium 20
XC 21/6
XC 22/5
XC 32/8
6
720
1122
210
-
9
3870
-
6
2400
3666
810
-
9
2520
3960
855
-
20.5
0.095
140
21
0.35
38
22.4
0.35
40
32
0.35
57
2.18 (55.4)
25.7 (652)
14.5 (368)
11 (279)
1.65 (41.9)
23 (10.5)
59.5 (27)
3.5 (89)
17.2 (438)
18.2 (464)
5 (127)
2.75 (70)
30 (13.6)
62.5 (28.3)
3.81 (97)
22 (559)
14.5 (368)
11 (279)
3.09 (79)
26 (11.8)
66 (30)
3.81 (97)
21.5 (546)
18.2 (464)
11 (279)
2.62 (67)
30 (13.6)
87 (39.5)
PERFORMANCE
Liquid nitrogen capacity L
Static evaporation rate L/day*
Normal Working Duration days**
UNIT DIMENSION
Neck opening in (mm)
Overall height in (mm)
Outside diameter in (mm)
Canister height in (mm)
Canister diameter in (mm)
Weight empty lb. (kg)
Weight full lb. (kg)
FIVE Year Vacuum Warranty
Conforms to MDD 93/42/EEC, the Medical Device Directive for the EU.
Cryo Sleeves
22 Cryopreservation Catalog
Canes
Measuring Stick
Roller Base
Cork
*
XC 33/22
XC 34/18
XC 43/28
XC 47/
11-6SQ
XC 47/
11-6
XC 47/
11-10
6
1260
1764
360
-
6
2100
3000
630
-
6
1260
1764
360
-
6 sq.
750
6
4500
6216
1320
-
10
3500
5000
1050
-
33.4
0.14
154
34.8
0.18
123
42.2
0.14
193
47.4
0.39
76
47.4
0.39
76
47.4
0.39
76
2.75 (70)
26 (660)
18.2 (464)
11 (279)
2.22 (56)
34 (15.4)
94 (42.5)
3.5 (89)
26.6 (675)
18.2 (464)
11 (279)
2.81 (71)
34 (15.4)
96 (43.5)
2.75 (70)
26.4 (670)
20 (508)
11 (279)
2.22 (56)
36 (16.4)
111 (50.5)
5 (127)
26.5 (673)
20 (508)
42 (19)
120.4 (54.6)
5 (127)
26.5 (673)
20 (508)
11 (279)
4 (102)
42 (19)
120.4 (54.6)
5 (127)
26.5 (673)
20 (508)
11 (279)
2.81 (71)
42 (19)
120.4 (54.6)
Static evaporation rate and static holding time are nominal. Actual rate and holding time will be affected by the nature of container use, atmospheric conditions, and manufacturing tolerances.
** Normal Working Duration is an arbitrary reference, to estimate container performance under normal operating conditions. Actual working time may vary due to current atmospheric conditions, container history, manufacturing tolerances and any
individual patterns of use.
Phase Separators
Gloves
Vapor Inserts
25 Vial Boxes
23
MVE Doble Series
The traditional method of export shipment and distribution for biological products such as semen and vaccines has involved wet
shipment under liquid nitrogen. In recent years, many traditional shipping companies have either prohibited the shipment of liquid
nitrogen, or placed hazardous material surcharges on shipments, making this method of transport uneconomical.
In many cases, vapor shippers have become the method of choice for cryogenic shipment. These shippers hold samples at cryogenic
temperature and allow a wide variety of shipping methods to be employed, even export shipments. Regarding transport, this is a perfect solution, regarding distribution, it is not. Once at the destination, the samples have to be
transferred into a liquid storage tank. Meanwhile, the shipping
container must be recovered by the shipping company, incurring
an additional “return shipment”.
Product Specifications
MODEL
Doble 11
Doble 20
6
6
660
660
Liquid Nitrogen Capacity l
10
18.5
Vapor Capacity l
3.1
2.8
Static Evaporation Rate l/day
0.17
0.1
Normal Working Duration days for liquid
37
116
Normal Working Duration days for vapor
17
21
Neck Opening in (mm)
2.18 (55.4)
2.18 (55.4)
Overall Height in (mm)
21.6 (549)
25.7 (652)
Outside Diameter in (mm)
10.2 (260)
14.5 (368)
11 (279)
11 (279)
1.65 (41.9)
1.65 (42)
17 (7.7)
25.2 (12)
22.5 (10.2)
30.2 (14)
Weight Full liquid lb. (kg)
36 (16)
60 (27)
Cabosil lb. (kg)
1 (.45)
1 (.45)
Number of Canisters
No. of 1/2 cc Straws 10/cane
PERFORMANCE
UNIT DIMENSIONS
Canister Height in (mm)
Canister Diameter in (mm)
Weight Empty lb. (kg)
Weight Charged vapor lb. (kg)
THREE Year Vacuum Warranty
Conforms to MDD 93/42/EEC, the Medical Device Directive for the EU.
Cryo Sleeves
24 Cryopreservation Catalog
Canes
Measuring Stick
Roller Base
Cork
The Doble Series tanks are the first units to be designed for both vapor shipment and liquid storage. A unique absorbent layer in the
base of the storage tanks enables them to be charged with nitrogen and employed as dry shippers with hold times of up to 30 days. Once
at the final destination, the tanks can be filled with liquid and used for long term storage, therefore avoiding the need for return
shipments.
Doble 28
Doble 34
Doble 47
Doble 47-10
6
6
6
10
2400
2100
4500
3500
28
32
46
46
8.4
6.7
8.4
9.6
0.35
0.2
0.4
0.4
50
100
74
72
24
30
21
21
3.81 (97)
3.5 (89)
5 (127)
5 (127)
22 (559)
26.6 (676)
26.5 (673)
26.5 (673)
18.2 (462)
18.2 (462)
20 (508)
20 (508)
11 (279)
11 (279)
11 (279)
11 (279)
3.09 (78)
2.81 (72)
4 (101.6)
2.81 (72)
34 (16)
39.2 (18)
47 (21.3)
48 (21.8)
49 (22)
51 (23)
63 (28.6)
64 (29)
84 (38)
95 (43)
125 (57)
120 (54.5)
3.5 (1.58)
2 (.9)
2.5 (1.2)
3.4 (1.6)
Phase Separators
Gloves
Shipping Carton
Vapor Inserts
25 Vial Boxes
25
MVE Vapor Shippers
MVE Vapor Shippers are designed for the safe transportation of biological samples at cryogenic (-150°C or colder) temperatures. Manufactured from durable, lightweight aluminum, they employ a hydrophobic compound which absorbs the liquid nitrogen to ensure
spill-free shipping. Because the absorbent is hydrophobic, it also repels moisture and humidity, assuring maximum holding time and
eliminating the necessity to dry units between uses.
A protective shipping carton is available for all models (except the SC 20/12V). This carton protects the container from being placed
on its side and helps withstand the rigors of transportation. These containers may be used to ship your samples with a “non-hazardous”
classification throughout the world, thus reducing costs and helping to assure sample viability.
Product
Specifications
MODEL
MAX. STORAGE CAPACITY
Number of canisters
No. of 1/2 cc straws 10/cane
No. of 1/2 cc straws 1 Level Bulk
No. of 1/4 cc straw 1 Level Bulk
No. of 1.2 & 2.0 ml vials 5/cane
No. of 1.2& 2.0 ml vials 6/cane
No. of blood bags stored 4R9953
SC 2/1V
SC 4/2 V
SC 4/3V
SC 20/12V
XC 20/3V*
1
88
182
9
-
1
280
440
938
95
106
-
1
120
210
452
40
48
-
6
540
780
1630
150
180
-
4 + 1 Center
2500/2000*
3750/3000*
7410/6000
675/560*
840/672*
-
1.5
0.19
8
3.6
0.26
13
4.3
0.20
21
12.3
0.09
85
6.8
0.3
23
1.4 (35)
13.5 (343)
7.25 (184)
5 (127)
1.2 (31)
6 (2.7)
8.8 (4)
2.75 (70)
18.4 (468)
8.7 (222)
11 (278)
2.62 (67)
11 (5)
17 (7.7)
2 (51)
19.4 (492)
8.7 (222)
11 (278)
1.81 (46)
13 (5.9)
20 (9.3)
2 (51)
25.7 (652)
14.5 (368)
11 (79)
1.5 (38)
30 (13.6)
52 (23.6)
3.81 (96.7)
25 (635)
14.5 (368)
11 (278)
3.2 (80)
23 (10.5)
35 (16)
PERFORMANCE
Liquid nitrogen capacity l
Static evaporation rate l/day
Static holding time days
UNIT DIMENSIONS
Neck opening in (mm)
Overall height in (mm)
Outside diameter in (mm)
Canister height in (mm)
Canister diameter in (mm)
Weight empty lb. (kg)
Weight charged lb. (kg)
THREE Year Vacuum Warranty
Conforms to MDD 93/42/EEC, the Medical Device Directive for the EU.
5-Level Rack
Canes
26 Cryopreservation Catalog
Measuring Stick
Cryo Block
Cork
IATA Shipper -150C Specimen Transport
MVE’s IATA Dewar has been independently tested and approved to meet current UN and IATA regulations concerning the transportation of potentially infectious substances. Test Data and Reports are available upon request.
* Please note that ALL other models of MVE Vapor Shippers can be legally transported by air (when shipping specimens that are not classified as or known to be potentially infectious).
Mini Moover
Cryo Shipper Mini
Cryo Moover
Cryo Shipper
Cryo Shipper XC
IATA
1
60
88
8904
20
24
-
-
7
3080
4354
945
1134
-
1 Rack
500
10
966 (Bulk)
10
1 Rack
-
2.9
0.20
14
5.9
0.84
7
4.2
0.35
12
8.5
0.85
10
10
0.7
14
11.8
0.8
14
1.4 (35)
19.5 (495)
7.2 (184)
11 (278)
1.2 (31)
8 (3.6)
11.6 (5)
8.5 (216)
20 (508)
11.6 (295)
16.5 (419)
34.3 (871)
3.8 (97)
22 (558)
18.3 (464)
11 (278)
3.1 (79)
30.5 (13.8)
38 (17.2)
8.5 (216)
21.5 (546)
14.5 (369)
24 (10.9)
37.5 (17)
8.5 (216)
23 (584)
15 (381)
12.5 (317.5**)
30 (13.6)
47 (21.4)
8.5 (216)
24 (610)
15 (381)
29 (131)
50.5 (22.9)
Static evaporation rate and static holding times are nominal. Actual rate and holding time will be affected by the nature of container use, atmospheric conditions, and manufacturing tolerances. Without center absorbent canister two week holding time, greater storage capacity.
* With center absorbent canister (3 week holding time)
** Useable Height
Phase Separators
Gloves
Vapor Inserts
25 Vial Boxes
27
Chart: Total
Cryogenic Solutions
Distribution
Air Separation
Bulk Storage Tanks
Dewars
Liquid Cylinders
Freezers
Security Through Systems
Chart Industries, Inc.
MVE, BioMedical Group
1800 Sandy Plains Industrial Parkway, Suite 316
Marietta, GA 30066
Ph 770-425-4470 • Toll Free 1-800-482-2473
Fax 770-425-4740
Chart BioMedical, Ltd.
Unit 2, Maxdata Centre
Downmill Road, Bracknell
Berks RG12 1QS, United Kingdom
Ph +44(0) 1344 403100 Fax +44(0) 1344 429224
www.chartbiomed.com
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