- Sapien Biosciences

SAPIEN BIOSCIENCES
Sapien Biosciences is a Bio-bank led R&D organization with focus on
Biomarker discovery and Diagnostics development
Sapien's association with Apollo hospitals help diagnostics, pharma and
drug discovery companies to do collaborative research using ethically
bio-banked patient samples
Patients are benefited by availability of cutting edge diagnostics through
Sapien in Apollo network and beyond
Exclusive access to clinical
tissue samples with associated
data & Access to KOLs
Front end for introducing
cutting edge diagnostics
at Apollo network
Personalized
Medicines
New Dx /
Prognostic Assays
BIO
BANK
Epidemiological
Studies
To utilize for in-house &
collaborative R&D with partners
Phenotypic
Drug Discovery
Platforms for
Drug Repurposing
Biomarker Identification /
Validation for diseases
Samples collected as per ICMR guidelines at par with any
International Guidelines
De-identified, coded samples in case of Prospective Collection
With informed consent in case of Prospective Collection
Developed in-house or
by collaborators
Ethically
approved samples
with peace of mind
for researcher
DIVERSITY OF SAPIEN BIO-BANK
ASSOCIATED DATA TO EMPOWER RESEARCH
Retrospective samples
50,000 patients' FFPE blocks and acquiring …
Tumor as well as adjacent non-tumor
Disease
status
Prospective samples
Diagnostic
Data
Pathology
Fresh tumor and adjacent non-tumor samples
Hematological tumors
Blood, Plasma, Serum
Saliva, Urine, BAL, Pleural fluid, synovial fluid etc.
Non-diseased specimens
Molecular
classification
Treatment
information
Recurrence
Follow ups
Health Check-up left over samples
Visits History
Family history
Serum / Blood / Urine - With extremely rich demographics
and biochemical data
 Sapien Bio-bank has over 50,000 patient samples banked in its
facility and access to over 0.5 million samples spread across
 Apollo network over the last 5 to 10 years that can be retrieved on
priority for studies
 Most samples have associated diagnostic data including pathology
reports, treatment, outcome & recurrence.
 Tissue tracking database implemented: First instance of caTissue
Plus (Open Specimen, Krishagni) implementation in India.
 Bioinformatics and IT infrastructure to accommodate BIG data
being put in place.
DIVERSITY OF SAMPLES - CANCER
HEART, VALVES, PERICARDIUM,
VASCULAR SYSTEM 94
BRAIN, SPINAL CORD, SPINE 831
MISCELLANEOUS E.G. PITUITARY /
MUSCLE / OCULAR ETC 222
DISEASE TYPES
SKIN (MEDICAL & SURGICAL) 818
BUCCAL MUCOSA, LIPS, TONGUE,
PALATE, DENTAL, JAWS, NOSE,
PARANASAL SINUSES, NASOPHARYNX,
LARYNGOPHARYNX/HYPOPHARYNX
OROPHARYNX/ADENOIDS/TONSILS,
MAJOR & MINOR SALIVARY
GLANDS, LARYNX, VOCAL CORD,
TRACHEA 1387
SOFT TISSUES, PERITONEUM,
MESENTERY, OMENTUM, ABD
WALL, FLUID 709
BONE MARROW, BONE,
SYNOVIUM, TENDONS, JOINTS 454
SPLEEN, THYMOS 18
LUNG, BRONCHUS-MEDICAl,
PLEURA, MEDIASTINUM 275
LYMPHOMA & ALLIED
DISORDERS 125
LYMPH NODES EXCLUDING
LYMPHOMA 388
BREAST 891
ECTOPIC PREGNANCY
GLIOBLASTOMA MULTIFORME
OF BRAIN
NON HODGKIN'S LYMPHOMA
DEGENERATIVE DISORDERS
CROHN'S DISEASE
TUBERCULOSIS
PULMONARY ARTERY STENOSIS
COLITIS
MISCELLANEOUS NECK, THYROID,
PARATHYROID 475
LIPOMA
ESOPHAGUS (ENDO & SURGICAL) 103
POLYPS
STOMACH (ENDO & SURGICAL) 315
VULVA, VAGINA, CERVIX, UTERUS,
ENDOMETRIUM, FALLOPIAN TUBE,
BROAD LIG, OVARY 2902
HIMANGIOMA
MENINGIOMA
CARCINOMA
INFLAMMATORY DISORDER
CYSTS
DUODENUM & SI (ENDO & SURGICAL)
APPENDIX 169
LARGE INTESTINE (ENDO &
SURGICAL) 570
ANUS 163
KIDNEY ( MEDICAL & SURGICAL) 383
PROSTATE/ SEMINAL VESICLES 829
TESTIS, EPIDIDYMIS,SPERMATIC
CORD (SURGICAL), TESTICULAR
BIOPSY, PENIS, SCROTUM 170
www.sapienbio.com
PANCREAS 31
RENAL PELVIS/URETER/RENAL
PAPILLAE, URINARY BLADDER/
URACHUS, URETHRA 166
ADENOMA
LEIOMYOMA
LIVER ( MEDICAL & SURGICAL) 121
GALL BLADDER & BILEDUCTS 411
ADRENAL & PARAGANGLIA 27
HYPERPLASIA
CHRONIC CHOLECYSTITIS
[email protected]
DIVERSITY - BRAIN CANCER SAMPLES
ASTROCYTOMA OF BRAIN
DIVERSITY - STAGES: BREAST CANCER
LOW-GRADE FIBROMYXOID
SARCOMA
ADENOCARCINOMA,
METASTATIC, NOS
HEMATOMA
INFLAMMATORY DISORDER
ANGIOMATOUS MENINGIOMA
62
GLIOBLASTOMA MULTIFORME
OF BRAIN
EPENDYMOMA NOS
Stage 0
116
83
NON-HODGKIN'S LYMPHOMA
ANAPLASTIC ASTROCYTOMA
OF BRAIN
27 18
Stage I
Stage IIA
GLIOBLASTOMA NOS
PILOCYTIC ASTROCYTOMA
PITUITARY ADENOMA
DIFFUSE NON HODGKIN'S
LYMPHOMA, LARGE CELL
MENINGIOMA NOS
CARCINOMA, METASTATIC, NOS
TRANSITIONAL MENINGIOMA
Stage IIB
144
Stage IIIA
NEOPLASM OF BRAIN
339
CRANIOPHARYNGIOMA
GANGLIOGLIOMA
Stage IIIB
Stage IIIC
MENINGOTHELIAL MENINGIOMA
GEMISTOCYTIC ASTROCYTOMA
OLIGODENDROGLIOMA,
ANAPLASTIC
CEREBRAL ARTERIOVENOUS
MALFORMATION
EPIDERMOID CYST
Stage IV
199
TRICHILEMMAL CYST
PRIMITIVE NEUROECTODERMAL
TUMOR
TUBERCULOSIS
TRIGEMINAL SCHWANNOMA
YOUR PARTNER IN RESEARCH
Effective roll out of tests across Apollo network with
the available Sapien machinery for BD, marketing,
logistics and more
Flow cytometry
Cell sorting
Fluorescent microscopy
Laser scanning confocal
ELISAs
Histopatholgy
Molecular Cytology:
Clinical Hematology
Clinical Microbiology
Clinical Immunology
SNPs, SNP arrays
NGS / or Sanger
Sequencing
Bioinformatics including
pathway/ systems biology
Proteomics
Biacore
HPLC
GCMS
LC-MALDI-TOF
X-Ray diffraction
CD
Bio-Bank
Resource
Technical
Expertise
Access to thought leader at Apollo for
feedback / beta testing during assay validation
Your organization
as a PARTNER
for Biomarker
Discovery/Diagnostic
test development
Research infrastructure available at Sapien/ NABL accredited Apollo laboratories or at strategic collaborators
Partnership & Collaboration
www.sapienbio.com
[email protected]
The Apollo advantage
Apollo, with it’s large expanse and by the mere number of
patients that it sees, is an abundant resource of diseased
tissue samples.
Apollo ecosystem also has an honest will to use them for
betterment of mankind by contributing to diagnostics and
drug development and also offering these new drugs /
diagnostics for their patients by bringing them to India.
Ludhiana
Gurgaon
Delhi
3,000,000
Out-Patients
325,000 +
Admissions
250,000+
Preventive Health Checks
13,000
Neuro Surgical Operations
500
Robotic Surgeries
1,000+
Kidney Transplants
375
Liver Transplants
150
Bone Marrow Transplants
150,000+
Radiotherapy Sessions
42,000+
Chemotherapy Sittings
120
Countries Medical
Valve Travel
Margoa
Nasik
Belapur
Pune
Lavasa
Bilaspur
Ranchi
Kolkata
Bhilai
Bhuvaneswar
Hyderabad
Vizag
Bellary Kurnool
Kakinada
Rachur
Nelloe
Aragonda
Tirupathi
Bangalore
Ayambakkam
Chennai
Tirunelveli
Trichy
Thirukadaiyur
Calicut
Karaikudi
Karur
Madurai
I ac
credit
8
H ac cr e d
10
ion
itat
5,000+
Joint Replacements
Mumbai Byculla
Thane
Indore
on
ati
10,000
Heart Surgeries
Ahemedabad
Bhagatpur
NAB
FY14 at Apollo hospitals
Bacheli
Agra
JC
Noida
Hospital owned by AHEL
Hospital owned by Subsidary /
Associates / Ms of AHEL
AHEL Affiliated Hospitals
Clinics / Diagnostic Centres
Under Construction
Explore with
How we can help with
prospective sample
collections for your study
specific requirements
CUSTOM SAMPLE
ACQUISITION
How our curated FFPE
blocks & data collection
can help validate your
hypothesis
TISSUE BANK
Contact us @
Phone: +91-40-6557-0007, +91-40-6558-0008
E-mail: [email protected]
www.sapienbio.com
How we can help in drug
discovery research using
patient derived discovery
platforms
DISCOVERY
PLATFORM
How we can partner with
you to bring KOLs on
board & launch your test
@ Apollo
VALIDATION &
LAUNCH
Sapien Biosciences Private Limited
Apollo Healthcity, Jubilee Hills,
Hyderabad - 500096
[email protected]