Shrink Fat on Your “Problem Areas,” Like the Hips, Thighs

S C I E N T I F I C U P D AT E
From iSatori Global Technologies
Shrink Fat on Your “Problem Areas,” Like
the Hips, Thighs, and Waist: Is It Possible?
New Study Offers Solid Proof!
Thanks to
Lean System 7,
“trouble spots” may
no longer be such
a burden. Find out
what new research
has to say about your
ability to shrink fat
on the places you
hate the most.
With our commitment to always
bringing you the most cutting-edge
information, we delve into a surprising new study that says you may be
able to target the most stubborn
zones of fat and lose them for good.
~ Prepared by Stephen Adele
Here’s the story… as you may know
(since I reported this in a previous issue
of Real SOLUTIONS), after nearly eight
millions dollars and ten years of diligent research, Dr. Henry Lardy discovered what many experts claimed to be
“the fountain of youth”—a micronutrient/metabolite called 7-Keto (a natural
substance produced by the body in our
adrenal glands, which declines with
age). It was originally released to the
market in 1998 and quickly became one
of the most sought after and widely
used “anti-aging” supplements in
America.
Later, on October 21, 1999, the groundbreaking results of a double-blind,
placebo-controlled study were published in the Journal of Exercise
Physiology, which revealed healthy
male and female participants who
supplemented with 7-Keto lost 3 times
more bodyfat (and dropped bodyfat
200% faster!) in only 8 weeks than
participants who followed the same
nutrition and exercise program but did
not use 7-Keto.
An April 2002 edition of Current
Therapeutic Research published a similar
clinical trial, which confirmed these
impressive findings. This research
revealed 7-Keto’s ability to help the
body metabolize fat at a much accelerated rate.
These landmark studies solidified the
patents on this breakthrough supplement, which continue to protect Dr.
Henry Lardy and Humanetics (the
manufacturer of 7-Keto). One such
prestigious U.S. Patent (# 5,296,481)
was awarded for use in weight loss
and weight management. Since then,
7-Keto has been awarded seventeen
other U.S. patents for additional health
benefits, such as improved immune
functioning, cognitive and memory
enhancement, and healthy skin.
In early 2002, an exciting, new supplement
company called iSatori
Global Technologies
decided to “up the
ante” in fat-loss technology by forging
a partnership with
Humanetics to develop
the novel supplement
called Lean System 7—
the first “advanced
metabolic activation
Lean System 7, with 7-Keto, was recently “put to the test” and faired exceptionally well.
74 Real Solutions
LEAN SYSTEM 7 STUDY RESULTS PRESENTED!
At this year’s Experimental Biology meetings held April 11, 2003, in San Diego,
California, Dr. John Zenk and his colleagues presented their recent findings on
Lean System 7. Reprinted below is a copy of that abstract.
468
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system” on the market. Lean System 7
was designed using the latest science on
7-Keto and combining it with other
equally powerful “metabolic-enhancing” supplements, such as yerba mate,
guarana, and forslean (coleus). Over the
last year, this supplement has become
wildly successful—rapidly becoming
the most popular non-ephedrine-based
fat-loss supplement to date.
Recently, Lean System 7 was thoroughly examined in a randomized, doubleblind, placebo-controlled clinical study
(the “gold standard” in research), and it
appears to be remarkably safe and
effective in helping individuals reduce
bodyfat, increase metabolic rate, and
preserve muscle mass. What’s even
more surprising, Lean System 7 was
shown to specifically reduce bodyfat in
those hard-to-reach “trouble areas,”
more commonly referred to as the hips
and thighs (for women) and the waist
or love handles (for men).
This landmark study was recently presented in abstract form at this year’s
Experimental Biology Meetings, which
was attended by more than 10,000 medical doctors, scientists, and researchers
who came together to share their work
and reveal the latest scientific findings.
John Zenk, a board certified internal
medical doctor, headed up this study as
the Principal Investigator at the
Minnesota Applied Research Center
(MARC). The study consisted of 47
healthy, slightly overweight male and
female adults (average age of 39).
Before the study, Dr. Zenk and his
research team measured the test sub-
jects’ body composition by DEXA
analysis (a highly accurate method for
evaluating lean mass and bodyfat). And
to make the study comprehensive, they
also measured the test subjects’ bodyweight, BMI (body mass index), BMR
(basal metabolic rate or the rate the
body burns calories at complete rest),
and waist and hip circumference.
During the eight-week study, all test
subjects were instructed to follow the
same nutrition program (consisting of
40% protein, 40% carbohydrates, and
20% dietary fat), and the same exercise
regimen (consisting of three-day-aweek mild exercise, such as a brisk walk
or jog).
What is a double-blind,
placebo-controlled study?
Ask any researcher the best way to
conduct a study—a “gold standard” if
you will—and you’ll get one answer:
double blind, placebo controlled.
A double-blind, placebo-controlled
study means that the study has certain
limitations set to prevent “contaminating” the study with the participants’ or researchers’ beliefs or expectations.
Placebo controlled, for instance,
means there are two groups of participants. One group uses the supplement, drug, or test substance, and the
other group uses a placebo.
Double blind adds another level of
protection. This simply means that neither the researchers nor the participants know which group they’re in.
They don’t know if they’re using the
supplement or taking the placebo, so
they won’t be influenced to think that
something is working or not.
So the next time you are looking at
study results, watch carefully for the
words “double-blind, placebo-controlled.” If you see them, you’re looking at a well-done, more accurate,
non-subjective study. You can depend
on the objectivity of the results.
www.RealSolutionsMag.com 75
S C I E N T I F I C U P D AT E
From iSatori Global Technologies
Results of the Study…
Minnesota Applied Research Center
18894 Lake Drive East, Charhassen, MN 55317
Change in Basal Metabolic Rate
(BMR)/Calorie Expenditure
Mean Change From Baseline
Placebo
group
Lean System 7 ™
group
iSatori Global Technologies, LLC
15000 West 6th Avenue
Suite 202
Golden, CO 80401
To Whom It May Concern:
Enclosed please find the results of our study with Lean System 7™, which was recently presented at the
meeting of the Federation of American Societies for Experimental Biology (FASEB). This annual meeting of
professional research scientists was held in San Diego on April 11-15, 2003, and had over 10,000 national
and international attendees.
The abstract for this study was accepted by the American Society for Pharmacology and Experimental
Therapeutics, Clinical Pharmacology division, and was presented formally at the meeting and published in
the FASEB Journal, Volume 17, Number 4, March 14, 2003, LB468.
Calories Burned Per Day
175
June 5, 2003
Based on the results of this controlled clinical study, Lean System 7 is a safe and effective formula for accelerating weight/fat loss and reducing waist and hip measurements in individuals following a healthy diet and
exercise program. The complete manuscript for this study has been submitted to a peer-reviewed scientific
journal for publication.
125
e
Burn
d 1,
C
More
391%
alo
ries!
100
75
50
25
0
Change in Weight Loss
Mean Change From Baseline
Placebo
group
In this clinical trial, healthy, overweight adults were given three capsules of Lean System 7 twice daily or an
identical placebo and followed a calorie-restricted diet and an exercise program for eight weeks.
Bodyweight, body mass index (BMI), basal metabolic rate (BMR), waist and hip circumference, and bodyfat
and lean tissue composition by DEXA were measured at baseline and week 8.
Lean System 7 ™
group
7 lbs
Overall Weight Loss
The results of the study revealed that the group taking Lean System 7 experienced a significantly greater
reduction in hip circumference measurement than did the group taking the placebo (4.85 cm vs. 2.34 cm).
Additionally, the Lean System 7 treatment group had significant reductions in bodyweight (2.9 kg), BMI
(0.97 kg/m2), and waist circumference (5.78 cm) with no change in muscle mass over the course of the study.
Furthermore, the BMR, which accounts for 70% of daily caloric expenditure, was also measured in this study,
and it is important to point out that the placebo group had the expected decline in BMR (-14 kcal/d) over
the 8-week period while the Lean System 7 group had a 1,391% increase (+178 kcal/d) in BMR. This illustrates a preservation of metabolic rate by Lean System 7 in the face of caloric restriction, which normally
results in a decrease in BMR. The largest increase in BMR by a subject taking Lean System 7 was a remarkable 930 kcal/d. Most importantly, there were no significant changes in vital signs, health assessment scores,
or adverse events between the two treatment groups, demonstrating that the oral administration of Lean
System 7 is safe and has a side effect profile that is no different than the placebo.
150
6 lbs
5 lbs
4 lbs
eigh
ore W
M
t
Los
t!!
3 lbs
2 lbs
1 lb
0 lbs
Change in Waist Circumference
Mean Change From Baseline
Placebo
group
Best regards,
Lean System 7 ™
group
Now, it’s important to point out that
this was a “blinded” study, with a
placebo. This means that none of the
test subjects knew who was getting
what. Both groups consumed a supplement that came in a generic bottle, and
all the capsules looked identical. Only
one group was taking the actual Lean
System 7 and the other was taking a
placebo (which was rice flour).
At the end of the study, researchers
once again evaluated the test subjects’
lean and fat mass (by DEXA), as well as
their bodyweight, BMI, BMR, and waist
and hip circumference. The study
results were very impressive (and interesting), to say the least! Here’s (above)
an exact copy of a letter iSatori received
from Dr. Zenk informing them of the
study results, which were presented at
the Experimental Biology meetings.
Although parts of Dr. Zenk’s letter are
rather complicated, I wanted to show
you this information, firsthand, just as
it was presented to the company who
markets Lean System 7, iSatori. (Talk
about being on the “frontline” of cutting-edge information… you saw it here
first!)
6 cm
5 cm
4 cm
c
Redu
ed B
e
t!
lly Fa
3 cm
2 cm
1 cm
0 cm
Change in Hip Circumference
Mean Change From Baseline
Placebo
group
Lean System 7 ™
group
7 cm
Over all Hip Reduction
John L. Zenk, MD
Medical Director and Principal Investigator
Over all Waist Reduction
7 cm
6 cm
5 cm
Over
Dou
he
ble t
Lo
Fat
ss!
4 cm
3 cm
2 cm
1 cm
0 cm
76 Real Solutions
Look, here’s the
reason I made
an entire feature
about this study—
this
is
not
just “pretty interesting stuff”; in
the realm of scientific research on fat
metabolism, it’s
literally groundbreaking!
Of course, one,
two, or three studies that demonstrate a particular
supplement can
obtain
certain
effects
doesn’t
necessarily mean
you can say the
data proves that
everyone
will
experience
the
same
results.
Check out the
While studies like
charts on the prethis offer solid eviIn today’s world of over-hyped, under-performing
vious page. They
dence of the type
“miracle dieting gimmicks,” it’s hard to tell the
reveal the astonof results experidifference between which ones will work for you
ishing results of
enced in a conand which ones won’t. Unlike guessing which will
the study. This
trolled environwork, scientific studies very often offer evidence
study suggests, for
ment, results can
(real, empirical data) that a particular supplement
the first time ever,
and will vary, even
may or may not work. Science offers a way to
using the same
that a supplement
objectively look at a supplement and first determine whether it’s
supplement and
may finally target
safe and effective. Following the latest marketing hype is an easy
following
the
particular places
way to throw your money down the drain (and possibly jeopardsame
the
nutrition
of
deep-stored,
ize your health). It appears much smarter to use a supplement
and exercise. In
hard-to-reach
that’s been rigorously tested in a clinical trial.
Don’t you agree?
essence, there are
bodyfat. Not only
no typical results.
that but with
But, doesn’t strong scientific evidence
no adverse side effects reported, Lean
make you feel much more confident
System 7 was proven just as safe as the
than marketing hype and simply guessplacebo (remember, that was rice flour).
ing?! I would think so.
To my knowledge, Lean System 7 is the
Don’t miss our next issue, where I’ll
only non-ephedrine-based fat-loss supgive you the results of a study which
plement that’s been clinically tested
Anthony Almada compared a pair
(and proven) to be both safe and effecof ingredients, and this combinative, with results of this magnitude.
tion outperformed both creatine
Obviously, I would recommend that
e
and a creatine cocktail. There’s
anyone who’s using any form of diet
h
t t
y
l
u
pill, thermogenic, or weight-loss
some very interesting data here,
n
r
is tpplemey!
supplement try Lean
which I can’t wait to share with
7
m w su toda pree
t
System 7. This evidence
you, especially for those
Sys lly ne theremore comn while
clearly shows that Lean
searching for increased musn
Leay totat out fat is that evexcess
System 7 appears to procularity and strength. In
onl oncep attacktso know g more de unlike t
duce greater, more targeted
each issue of Real SOLUc way it cool s usin t. An me jus s.
effects than any other fat-loss
TIONS, I’ll try to keep you
i
a
s
s
The ve... It’ body ming f gives lertne d
y
7
i
supplement out there.
up to date on the latest scie
a
m
s
z
hen leep, m nd tri ystem gy and energi er
s
a
entific discoveries in suph
S
l
r
I
rat
fee
e
an
rgy
ene
ene ra, Le st of way: I em 7, ally lik
plementation, which I
o
ed
re
s
st
eph ight bo it thi an Sy aky. I 7.
feel would be the most
t
h
e
r
the me pu with L and s System
interesting and useful
Let aler t ked up Lean
to you. Stay Tuned!
d
c
n
ut
ja
MARKETING
HYPE
John L. Zenk, MD
VS. SCIENTIFIC PROOF
a
o
ll
n a hat ab
tha
t
www.RealSolutionsMag.com 77
WHICH FAT BURNER IS RIGHT FOR YOU?
By Sue Mosebar*
L
osing weight isn’t easy. Choosing a fat-burner supplement can be even harder. With hundreds to choose from, it
can be downright confusing. The good news is fat burners do work (at least some of them anyway!), and they can
help you get rid of ugly, unsightly bodyfat faster than diet and exercise alone. Here are our favorites… top fat-burner
supplements backed by solid scientific evidence, proven to work, and which have satisfied thousands of people already.
Find out which one is right for you…
MX-LS7™ THE HIGH-PERFORMANCE
FAT BURNER FOR MEN AND BRAVE WOMEN
Rated the #1 Best in Class Fat Burner by Jeff Everson’s Planet Muscle
magazine, new MX-LS7 is perfect for men and brave women
who want an extreme thermogenic that delivers maximum
intensity and strips away fat, fast. Starting with the “core” from
the original clinically researched Lean System 7 formula, iSatori then
seriously amped up the intensity and thermogenic impact using the
most powerful, cutting-edge ingredients
known to science... to create MX-LS7. MXLS7 is the only formula to contain Rapid BioDiffusion Delivery Technology™, so it starts
working from the very first dose to eliminate
stubborn bodyfat, fast. For those who want
all the “perks” that come with chiseled,
granite-like abs, there’s only one obvious
choice: MX-LS7. Nothing is stronger. Nothing
works faster. (MX-LS7.com)
LEAN SYSTEM 7 ADVANCED
METABOLIC SUPPORT
®
Voted the #1 fat-burner supplement by UltimateFatBurner.
com (the web’s premier source for online reviews of weight-loss
supplements), Lean System 7 has been used successfully by over
one-million people since its introduction over five years ago. Lean
System 7 is perfect for men and women who are trying to
lose those last 10 to 20 lbs. Lean System 7 contains a patented
form of 7-Keto, a substance naturally
produced in our bodies that declines with age
and is the primary reason our metabolisms
slow down. Lean System 7 was found in a
recent scientific study to safely increase
your metabolism, so you can turn back the
clock to more youthful, active metabolism
and finally shed those unwanted pounds.
(LeanSystem7.com)
CURVELLE™ NATURAL WEIGHT LOSS FOR WOMEN
New Curvelle is the perfect diet pill for women searching for
a natural way to faster weight loss. Using only pure, natural
ingredients, Curvelle is a significant weight-loss breakthrough
because it works to speed up your weight loss by slowing down blood
sugar—preventing spikes and crashes to eliminate your cravings for
sugar and other foods that can wreck your diet, while rapidly burning
excess calories for energy. When taking Curvelle, you’ll experience
more energy, but thankfully, you won’t be over-stimulated, and it
won’t upset your stomach (unlike other fat-loss supplements!). And
because Curvelle contains special antioxidants, it is ideal for women
who want to look younger and
more radiant on the outside,
but just as importantly,
want to feel healthier on the
inside. Curvelle does work
fast though, as users have
reported losing up to seven
pounds in the first week!
(MyCurvelle.com)
ENERGIZE™ THE ALL-DAY ENERGY
AND CALORIE-BURNING PILL
Boasted as the #1 Energy pill by retailers
nationwide, Energize is perfect for men and
women who want sustained energy and allday calorie burning. That’s because Energize
was developed to safely give your body back
the energy it needs and to keep your energy
levels up longer. In fact, as the clinical studies
suggest, one dose of Energize in the morning keeps you energized
all day long. Combining a unique blend of B-vitamins, minerals, and
amino acids, Energize works with your body’s natural ability to burn
calories for energy and is ideal for those days when you need to boost
your energy, fight off midday fatigue, and think more clearly... all
while burning extra calories. (EnergizeMyLife.com)
EDITOR’S NOTE: These fat-burner supplements are available at retailers nationwide. Or, check out their websites, where you can order direct,
find out more information, or locate your nearest retailer. (Bonus: they all come with a no-questions-asked 60-day money-back guarantee.)
*Sue Mosebar is the Executive Editor for Real SOLUTIONS for your best body (RealSolutionsMag.com)
34 Real Solutions
© 2008 iSatori Technologies, LLC. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. In a recent clinical trial,
www.RealSOLUTIONSMag.com
35placebo
subjects taking the Lean System 7 formula had a significant increase in resting metabolic rate (7.2% versus a .07% decrease in the placebo group) and a significant decrease in hip circumference
(3.78 cm versus 2.07 cm in the
group.) While one study subject did lose up to 19 lbs, the average weight loss in the Lean System 7 group was 6.38 lbs over 8 weeks. Your results may vary.