FreshaxylTM - Eurotrading

Freshaxyl
TM
Managing odors caused by perspiration has been a long-time focus of bodily care. The daily
application of a deodorant is an essential step for both men and women. While the product
variety is abundant in terms of application and scenting, the active molecules are very similar
to each other. Triclosan acts as the reference active molecule, but today’s market demands
solutions that are more natural.
Here at Beauty Creations, we recognize that it is possible to combine effectiveness with
naturalness. This is precisely why we have created FreshaxylTM.
Specially designed for deodorant applications, FreshaxylTM is a plant-based, high-performance
alternative to synthetic anti-odor molecules.
Fresh and pure all day, in the most natural way in the world.
FreshaxylTM leverages all of Beauty Creations’ expertise in the development of active ingredients
used in bodily care products.
FreshaxylTM is a synergistic blend of two plant-based compounds: an extract from the Moringa
oleifera plant and glyceryl laurate.
FreshaxylTM works at two levels for optimal effectiveness: through its bactericidal activity, it slows
down the proliferation of microorganisms and Moringa oleifera extract, which is known for its
detoxifying properties, thus capturing odors.
The plant
Moringa oleifera is an exotic tree reaching 5 meters in height.
Originating from India, the plant grows in tropical and subtropical
regions mostly in Africa and Asia. In Africa it is called nabeday (from
‘’never die’’), or the drumstick tree due to its long pods. It produces
white flowers that bear fruit resembling long pods. These contain
sphere-shaped seeds with little wings.
The moringa is largely used in these regions for its nutritional (pods)
and medicinal (leaves and flowers) properties. The crushed seeds
are also known for their ability to purify dirty water, particularly from
Proven effectiveness
Perspiration in itself does not produce an odor. The formation of bodily odors is linked to the
development of bacteria present on skin.
The vast majority of these microorganisms are Gram + based, and the Corynebacterium remains
preponderant. These bacteria produce enzymes capable of decomposing different odorless
precursors that are present in sweat as part of odorous molecules.
FreshaxylTM's performance has been clinically proven in comparison to the leading reference
molecule on the market: triclosan.
Its bactericidal activity on the Gram + strains responsible for the apparition of bodily odors has
been demonstrated in vitro. FreshaxylTM reduces the proliferation of these bacteria as does
triclosan.
FreshaxylTM's effectiveness in vivo derives from this inhibitory ability.
The latter has been proven by a clinical study, in which FreshaxylTM not only significantly reduced
the production of bodily odors, but did so as efficiently as the leading molecule on the market.
FreshaxylTM is effective for 24 hours, starting at the very first application.
Properties
Reduction of odors.
Applications
Deodorants.
Anti-odor bodily care.
Foot cream.
Intimate hygiene.
Proof of concept
Antibacterial action compared to triclosan
MIC in % of the tested products
The performance of FreshaxylTM has been demonstrated in vitro on the leading
bacterial strains responsible for the formation of bodily odors.
0.06
0.05
0.04
0.03
0.02
0.01
0.00
a
b
c
d
e
Triclosan
Freshaxyl™
a: Brevibacterium epidermidis
b: Corynebacterium minutissimum
c: Corynebacterium xerosis
d: Micrococcus luteus
e: Staphylococcus epidermidis
In vitro study.
A measure of Freshaxyl™’s ability to inhibit the growth of dermal microflora, including the bacteria responsible for
bodily odors. The determination of Freshaxyl™’s Minimal Inhibitory Concentration (MIC) level as compared to that of
triclosan, using the agar dilution method.
A demonstrated
clinical effectiveness
FreshaxylTM significantly reduces the intensity of odors caused by perspiration.
A measurable reduction of odors caused by
perspiration
Delta Perspiration Smell Intensity
(Treated - Non-treated)
6 hours after treatment
1
0.5
0
-0.5
-1
-1.5
** ***
-2
-2.5
-3
-3.5
Before
One
treatment
application
***
**
Six
applications
Effectiveness
comparable to triclosan.
Delta Perspiration Smell Intensity
(Treated - Non-treated)
24 hours after treatment
1
0.5
0
-0.5
-1
-1.5
-2
***
**
-2.5
-3
-3.5
Before
One
treatment
application
*
**
Six
applications
Significant effect up to
24 hours after application.
Stick containing 0.25% Triclosan
Stick containing 0.40% Freshaxyl™
Statistics: comparison / before application. Student T test or Wilcoxon T test (according to the normality of the distribution).
* p<0.05 - ** p<0.01 - *** p<0.001
Delta Hedonic Value
(Treated - Non-treated)
Effect felt by the testers
6 hours after treatment
2
1.5
**
1
*
0.5
0
-0.5
Before
treatment
***
**
One
application
Six
applications
Delta Hedonic Value
(Treated - Non-treated)
Effective from the very
first application.
24 hours after treatment
2
1.5
**
**
1
**
**
0.5
0
-0.5
Before
treatment
One
application
Six
applications
Stick containing 0.25% Triclosan
Stick containing 0.40% Freshaxyl™
Statistics: comparison / before application. Student T test or Wilcoxon T test (according to the normality of the distribution).
* p<0.05 - ** p<0.01 - *** p<0.001
In vivo study.
Tested on two groups of 15 subjects. Daily application of a deodorant formula containing 0.40% FreshaxylTM or 0.25%
triclosanTM under the arms over 6 days, versus untreated. Sensory evaluation by a trained jury (5 people), evaluating
the intensity of the perspiration odor, as well as the hedonic value of the odor, 6 hours and 24 hours after 1 and 6
successive applications.
Summary
REFERENCE FreshaxylTM LS9980
DESCRIPTION Freshaxyl™ is the combination of glyceryl
laurate and Moringa oleifera seed extract obtained, as a
powder, by prilling technology
DOSE OF USE 0.40%
REGULATORY DATA
INCI (US) Glyceryl Laurate, Moringa Oleifera* Seed Extract
*Moringa Pterygosperma Seed Extract could be used as a synonym
CAS 142-18-7, 93165-54-9 (999999-99-4)
EINECS 205-526-6, 296-941-1 (310-127-6)
China Each component listed in IECSC 2010 and in
International Cosmetic ingredient standard Chinese name
(2007 & 2010 versions) as well as 1st batch IECIC 2013
Preservative None
Solvent None
preliminary specifications
Organoleptic characteristics Beige powder, with weak
characteristic odor
Microbiological test Total germs < 100 CFU/g
Pathogens Absent
Gram negative bacteria Absent
Water content (%) 0.0 - 5.0
Saponification value (mgKOh/g) > 150
Acid value (mgKOh/g) 0.0 - 5.0
Total nitrogen (%) > 0.4
Commercial sample of FreshaxylTM sample and example of formulas.
Formulation
Freshaxyl™ can be incorporated into the oil phase before
making the emulsion.
Recommended pH: 4-7
TOXICOLOGy
Available data upon request.
CUSTOMS CODE 38 24 90 97
STORAGE
Store properly at room temperature (recommended 1525°C) in original sealed container, and protected from light
and from moisture.
SHELF LIFE 24 months
MANUFACTURER
BASF Beauty Care Solutions France SAS
3 rue de Seichamps
54425 Pulnoy (France)
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believed to be accurate and reliable, they are presented gratis and
for guidance only, and risks and liability for results obtained by use
of the products or application of the suggestions described are
assumed by the user. SELLER MAKES NO WARRANTY OF ANY
KIND, EITHER EXPRESS OR IMPLIED, BY FACT OR LAW,
INCLUDING
WARRANTIES
OF
MERCHANTABILITY
OR
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suggestions concerning possible use of the products are made
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patent. The user should not assume that toxicity data and safety
measures are indicated or that other measures may not be
required. The claims and supporting data provided in this
publication have not been evaluated for compliance with any
jurisdiction’s regulatory requirements and the results reported may
not be generally true under other conditions or in other matrices.
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