Maquetación 1 - Diabetes Research Institute
Transcription
Maquetación 1 - Diabetes Research Institute
Diabetes Research Institute Foundation DRIfocus Summer 2008 / Volume 36 / Issue 1 Miami / New York / Long Island / California / Washington, D.C. DRI DISCOVERS IMPORTANT REGULATOR OF BLOOD SUGAR Researchers from the Diabetes Research Institute’s Islet Physiology Laboratory and the Karolinska Institutet in Stockholm, Sweden, have identified an important mechanism that helps the body maintain normal blood sugar levels. The novel study was important enough to be featured on the cover of the June 2008 issue of the prestigious journal Cell Metabolism. The regulation of normal blood glucose levels relies primarily on the function of two types of cells that are found inside the islets in the pancreas – beta cells which produce insulin, and alpha cells which produce glucagon. These cells work together to maintain a delicate balance for normal blood sugar levels and prevent both hyperglycemia (high blood sugar levels) and hypoglycemia (low blood sugar levels). Alpha cells release glucagon when there is an increase in insulin production and/or a drop in blood sugar levels. In individuals with type 1 diabetes, this mechanism is impaired or lost altogether. The research team, led by Drs. Per-Olof Berggren, Alejandro Caicedo and Over Cabrera, found that, in addition to glucagon, pancreatic alpha cells also release glutamate, a > Continues on Page 6 Fluorescent markers identify specific cell types within the same islet. Image D combines the insulin, glucagon and glutamate-containing cells involved in the complex regulation of normal blood sugar levels. DRI FOUNDATION SURPASSES FIVE-YEAR GOAL TO RAISE $100 MILLION “…The DRI Foundation now ranks among the leading diabetes fundraising organizations in this country and internationally…yet we remain unique in the world of diabetes.” > See Chairman’s Message on Page 2 Dare to Dream A Silver Anniversary Recently retired NY Giants defensive end Michael Strahan included himself in the golf foursome that he auctioned off at D.R.E.a.M.S. in the City. Former Dolphins quarterbacks Don Strock and Dan Marino celebrated the 25th annual Don Strock Diabetes Classic. > Articles on Pages 16 > Article on Page 13 Armani Exchange Supermodel DRI Golf Classic in CA Tackling Diabetes Supermodel Izabel Goulart proved that “Giving Never Goes Out of Style” through her support of the DRI at the Armani Exchange store in NYC's Soho. Sports Journalist Roy Firestone and Baseball Great Don Baylor played integral roles in the DRI Golf Classic in California. New England Patriots nose tackle Vince Wilfork hosted his fifth Draft Day fundraiser benefiting the DRI. > Article on Page 12 > Article on Page 17 > Article on Page 13 A Message from the Chairman Dear Friends, The close of the Diabetes Research Institute Foundation’s 2007/08 fiscal year on June 30th marked the end of our five-year plan to raise $100 million for the Diabetes Research Institute. We are extremely pleased to announce that not only have we achieved our goal, but have surpassed it by 25 percent, raising more than $125 million over the last five years! This is an extraordinary accomplishment and one that could not have been realized without the unwavering generosity of our donors. The DRI Foundation now ranks among the leading diabetes fundraising organizations in this country and internationally. Yet with our singular focus on curing those living with this disease, we remain unique in the world of diabetes. What is perhaps most notable is that almost 40 percent of the funds raised during this campaign, across all donation levels, came from contributors who had never before given to our organization, including many of you reading this issue of DRIfocus. The importance of planned gifts cannot be overstated as the DRIF was the beneficiary of a number of bequests throughout these past few years. The legacy created by these generous individuals will help to transform the futures of those living with this disease. The significant involvement of our lay leadership also contributed immensely to the success of our campaign. Many new members have joined our National and Regional Boards of Directors, which are comprised of dedicated individuals from around the United States and as far away as Italy and England. Our leadership’s personal connection to diabetes and passionate resolve to find a cure drives them to support the DRI and to engage others within their own communities who share our mission. Clearly the work of the DRI and Foundation is attracting the attention of those who seek accountability, transparency and a focused mission when supporting a diabetes organization. For each of the past two years, the DRI Foundation has earned a four-star rating, the highest possible, from Charity Navigator, the nation’s largest independent evaluator of charities. Only 15 percent of all charities evaluated have received back-to-back four-star ratings, indicating that “the Diabetes Research Institute Foundation outperforms most charities in America in its efforts to operate in the most fiscally responsible way possible.” Each and every donor can feel confident that their contributions were stewarded in the most responsible and efficient manner. Your critical support of the Foundation has enabled the DRI to pursue the newest directions in science, merging traditional research approaches with cutting-edge, emerging technologies. Armed with these powerful tools, DRI scientists are re-engineering the path to a cure for those living with diabetes. We invite you to learn more about these promising research developments, some of which are covered in this issue. As we embark on a new year and a new plan, we will be sharing some exciting information with you in the months to come. You have played an integral role in the DRI’s tremendous progress and we hope to count on your continuing support. We are all working together for a common goal and each of you is needed now more than ever before. Thank you again for your generosity and commitment to this organization. Sincerely, Thomas D. Stern Chairman of the Board ANTHONY E. CHILDS SELECTED TO LEAD FOUNDATION’S LONG ISLAND OFFICE As the DRI continues its life-saving work toward a cure for diabetes, it is more critical than ever for the Foundation to raise the increased funds necessary to support its many cutting-edge initiatives. Efforts in Long Island have been key to the Foundation’s overall success. In order to fulfill its financial obligation to support the DRI, the Foundation must continue to grow and attract new donors.To help spearhead additional fund-raising opportunities, Anthony E. Childs has been appointed Long Island regional director. “I am excited to be involved with an organization that is so focused on finding a cure for diabetes,” said Tony. “On my visit to the Diabetes Research Institute, I was inspired by the drive and the commitment of the scientists working there. I have taken it on as a personal mission to ensure that these researchers have the funds they need to continue their important work.” Tony joins the organization after a long and established tenure in the nonprofit arena, where he held senior development and marketing positions with human services and healthcare organizations. He has worked closely with several boards of directors and various committees to achieve results at the American Cancer Society as director of major gifts, St. Catherine of Siena Medical Center in Smithtown as vice president of development, and the Interfaith Nutrition Network as director of development. Tony holds a master’s degree in nonprofit management and is an active member of the Association of Fundraising Professionals. Additionally, he has gained nearly a decade of experience in the insurance/financial services industry. “We have experienced overwhelming growth over the last several years, and it became necessary for the Foundation to add senior level leadership so that we can continue our momentum. Tony brings tremendous strength to this organization, and we are thrilled to have him join us,” said DRI Foundation President and CEO Robert A. Pearlman. NEW DIRECTORS JOIN NATIONAL, REGIONAL BOARDS Pictured left to right: Mark H. Ayers, William Fishlinger, Glenn Kleiman, Alan S. Kava, Steven Silva and Bruce Waller. The Diabetes Research Institute Foundation is pleased to announce the appointment of three new members to the National Board and three new members to the regional boards. National Board member Mark H. Ayers of Baltimore, MD, is the president of the Building and Construction Trades Department of the AFL-CIO. Prior to his unanimous election on September 6, 2007 as president of the BCTD, Mark was the director of the Construction Maintenance Department of the International Brotherhood of Electrical Workers (IBEW) and chair of the National Maintenance Agreements Policy Committee (NMAPC). He has held other positions within the IBEW and attended the George Meany Institute for Labor Studies (now known as the National Labor College), the University of Wisconsin, the University of Illinois Institute of Labor and Industrial Relations, and the International Foundation for Employee Benefits. He also served his country as an aviator in the United States Navy. The men and women of the BCTD are the Foundation’s largest contributors. The partnership reached a milestone when the unions funded and built the Diabetes Research Institute facility in Miami, and they continue to raise millions of dollars for the DRI each year through their Dollars Against Diabetes (DAD’s Day) and other campaigns. National Board member William Fishlinger of Plandome, NY, is chairman and chief executive officer of Wright Risk Management and is also the senior partner and president of the law firm of Congdon, Flaherty, O'Callaghan, Reid, Donlon, Travis & Fishlinger. Bill has been recognized for the creation of some of the most innovative and successful risk financing vehicles, including NYMIR and NYSIR, and has lectured extensively in the areas of general litigation, environmental law, medical malpractice, risk management and insurance. A graduate of St. John's University School of Law and the State University of Maryland, he is admitted to practice law in both the Federal and State courts of New York. He also served in the United States Air Force. He and his wife, Joan, established the Future Leadership Foundation, whose mission is to control, prevent and cure juvenile diabetes and other conditions that threaten the future of young people. Both Bill and Joan are active members of the Long Island Regional Board’s Executive Committee. Their tireless efforts are in honor of their daughter, Alex, who has type 1 diabetes. They also have a son, Matt. National Board member Glenn Kleiman of Fox Point, WI, is president and owner of Fullhouse, an interactive marketing agency in Milwaukee and Chicago. Fullhouse provides services—such as website development and interactive games—for leading business-to-consumer and business-to-business brands. Born in Miami Beach, FL, Glenn attended Northwestern University, where he received a bachelor’s degree from the Medill School of Journalism. He began his professional career as a television news reporter and manager, winning four Emmy Awards and a Peabody. He founded Fullhouse in 1989. His parents have been supporters of the DRI Foundation since its earliest beginnings. Glenn's late father, Marty, served as chairman of the National Board. His mother, Marge Kleiman Mintz, continues to serve on the Florida Regional Board. His brother, Gary, and his daughter, Alison, 23, have type 1 diabetes. He and his wife, Gisela Terner, also have another daughter, Marley, 16. Northeast Board member Alan S. Kava of New York City is the chief financial officer of the Whitehall Street Real Estate Funds, a division of Goldman Sachs. He joined Goldman Sachs as a vice president in 1997 and became a managing director in 2002. Prior to joining the firm, he worked as an associate attorney in the Corporate and Real Estate Departments of Simpson, Thacher & Bartlett. Alan earned a BA in economics from the University of Virginia in 1987 and a JD from New York University’s School of Law in 1990. He and his wife, Lisa, have two children, Ben, 9, who has type 1 diabetes, and Zoe, 6. Northeast Board member Steven Silva of Long Island, NY, is the president and chief operating officer of Chem Rx, a major, long-term care pharmacy. He is responsible for overseeing the operations and workflow at Chem Rx’s five sites, with continued focus in sales, marketing and client services. During his 16-year tenure, he has held several positions within the company, including director of corporate operations and vice president of sales and servicing. A graduate of New York University, Steven is involved with a number of charitable organizations and also offers guidance to over a dozen healthcarerelated non-profit organization committees. Steven’s mother battled type 1 diabetes for much of her life, and he is determined to help find a cure. He and his wife, Shanna, have three children, twins Robert and Brandon, 7, and Alex, 3. Long Island Board member Bruce Waller of Upper Brookville, NY, is the president of Gold Coast Properties and Development, LTD. and of GW Development, LLC. He is involved in private real estate development, operation and management and is also a New York State licensed real estate broker. Prior to this, he served as an executive of a large private manufacturing and import/export conglomerate and as president of Décor, Inc. Bruce is also a member of the board of directors at Congregation Teferith Israel. He and his wife, Long Island Board member Roberta Waller, have been dedicated supporters of the DRI ever since their daughter, Dara, was diagnosed with type 1. They also have two sons, Andrew and Skylor. At the National Board’s May meeting, the 39-member group also paid tribute to outgoing directors Samuel J. Fox, Eugene Milgram, Marge Kleiman Mintz and Edward James Olmos. These individuals will now serve on the Honorary Board. 3 | 1 2 1. Sue (2nd from left) and Norman Kenyon with their daughters, Pam Kenyon (far left), Dr. Norma Sue Kenyon (2nd from right) and Cyndi Drake (far right). 2. The Kenyon family will stop at nothing until they find a cure for Laura Mauriello. THE KENYON FAMILY'S MISSION Medicine practically runs in the Kenyon family’s blood. Patriarch Dr. Norman Kenyon is a retired surgeon who volunteers his services in the labs at the Diabetes Research Institute. Past chief of staff at both Baptist Hospital and Doctors Hospital in South Florida, he continues to serve as trustee of Baptist Health and chairman of the board at Doctors Hospital. His wife, Sue, is a registered nurse, and their three daughters all work in the medical field – possibly the most recognized being the DRI's Dr. Norma Sue Kenyon. But it’s the third generation that drives their passionate commitment to find a cure for diabetes. Sixteen-year-old Laura Mauriello, Sue and Norman's granddaughter and Norma’s daughter, was diagnosed as an infant, and the family will stop at nothing until a cure is found. For Norman, working in the DRI labs side-by-side with his daughter, and serving on the Foundation’s Florida board, simply weren’t enough. He wanted to do more. As a retiree living on a fixed income, he determined that the best way to maximize a financial gift was through life insurance.Together, he and Sue made the DRI Foundation the beneficiary of their life insurance policy which provided them with an immediate tax deduction for the lesser of the policy’s fair market value or the net premiums paid. In order to build value in the policy, the Kenyons continue to make contributions to cover the cost of subsequent premiums. This provides them with an annual deduction as well. “I’m very tied in to fundraising, and it was clear to me that life insurance was the best option for us,” said Norman. “My connection to the cause couldn’t be more personal, having a granddaughter with diabetes and a daughter who is working to come up with a way to correct, cure or eliminate diabetes. “I’m also very proud that I can continue to teach, train and test different techniques at the DRI. There are so many complexities to achieving our goal; the only way to do it is by working methodically and persistently,” he concluded. With Norman and Sue’s gift, their names join dozens of others on a commemorative wall at the Diabetes Research Institute as members of the DRI Heritage Society. There are a number of ways that insurance can be used to support the DRI. By naming the DRI Foundation as the beneficiary of your life insurance policy, you can turn a relatively modest annual outlay for the premium into a much larger gift, and you will receive an estate tax deduction for the insurance proceeds. To learn more about utilizing life insurance to make a charitable gift, please contact the DRI Foundation office at 800-321-3437 or [email protected]. DRIF’s Jeffrey Young JOINS FICPA BOARD OF GOVERNORS Individuals who ensure the future of the DRI through generous provisions made in their estate plans via wills, life insurance, charitable remainder trusts, charitable gift annuities and other planned giving vehicles are recognized as part of the DRI Heritage Society. Members are included on a designated wall of honor at the DRI. They receive a special award, are invited to attend one of the DRI Foundation’s annual donor appreciation dinners, and are listed in the DRI Annual Report and several other publications. If you have made provisions for the DRI or are planning to do so, we would like to include you in this special group of supporters. By becoming part of the Heritage Society, you are providing us with the opportunity to express our gratitude while inspiring others to support the DRI through their estate plans as well. Please call 800-321-3437 to learn more. Jeffrey Young, chief financial officer of the Diabetes Research Institute Foundation, has been elected to the Board of Governors of the Florida Institute of Certified Public Accountants (FICPA). Jeff will represent the DRIF and other not-for-profit organizations based in the state of Florida. “It is an honor to be recognized by your peers and to serve on the board,” said Jeff, who chaired the FICPA’s Not-for-Profit Organization Conference held in Ft. Lauderdale and Tampa last year. Jeff has worked for the DRIF for the past 14 years after spending the earlier part of his career in public accounting and industry. Tallahassee-based FICPA was founded in 1905. It is a professional association representing more than 19,000 member CPAs throughout Florida FROM ONE GENERATION TO THE NEXT “Dad, don’t worry. God wanted me to be just like you.” Most parents would be thrilled to hear such meaningful words spoken by a child. But for John Reisman, his young daughter’s sentiment struck him with an enormity of emotions that were far from simply pride and joy. A true “daddy’s girl,” the pair shares the same hair color and a love of swimming, tennis and boating. His eldest daughter even loves to tag along with John at work, where she has her very own office. But when Julia, 11, was diagnosed with type 1 diabetes, it was one thing John hoped they would never have in common. “The day I found out Julia had diabetes was probably the most difficult day of my life. Much harder than the day I was diagnosed. It couldn’t even compare,” said John, who has been living with this disease since he was 14. John Reisman with daughter Julia. “This disease is epidemic, not only in our family but in the world today. We need to find a cure,” stated Kim. “My family and I believe the DRI is the best hope for a cure, and we want to focus our fundraising efforts on the Institute.” While John was away on business, his wife, Lisa, recognized a telltale sign in Julia, who was 7 at the time. “It was her sweet-smelling breath – something Lisa had recognized on me when I had high blood sugars. She took Julia to the hospital and said to the nurse,‘I think my daughter has diabetes. Test her,’” John recounted. “When the nurse questioned her, Lisa said,‘I just know.’” Kim and John hail from a family of philanthropists, most notably their maternal grandparents, Norma and Jack Parker, who created the Jack Parker Foundation. This family foundation supports various charities, mostly medical-related, such as the Parker Jewish Institute for Health Care and Rehabilitation and the Diabetes Research Institute. John is also the president of The Jack Parker Corporation – Florida, a real estate development company located in Fort Meyers. Unfortunately, John’s family knows the signs and symptoms of diabetes all too well. His grandmother and great grandmother had type 2. Following Julia’s diagnosis, his mother, Jane Parker, also developed type 2, and his aunt was diagnosed with type 1. Finding a cure has become the family’s top priority and they have channeled their efforts in support of the Diabetes Research Institute. Earlier this year, Lisa and John, as well as Jane, each served as Platinum Sponsors of the Foundation’s D.R.E.a.M.S. in the City event. One of John’s four sisters, Kim Dickstein, joined the Foundation’s Northeast Regional Board and is very active in helping to raise funds and awareness for the DRI. 1 2 “My grandparents used to say,‘It’s so much easier to give than to ask,’” said John fondly, and he tries to pass this trait along to his own children, Julia and Jayda, 9. John recently toured the DRI in Miami, spoke with the scientists and saw firsthand the life-saving work being conducted there. “I was very impressed and felt that the DRI is probably our biggest hope to finding a cure. If you have faith and dedication, it will happen,” he concluded. 3 4 5 6 CYCLE OF DISCOVERY AWARDS HYPOTHESIS AWARD: (1) Barbara Annis, (2) Ric Carter of Fluor Construction QUERY AND HYPOTHESIS AWARDS: (3)Don Strock presents to Mary Jo (not pictured) and Bruce Schumin. (4) Barbara Singer presents to Elizabeth and Gary Hall, Jr., with baby Charlie. QUERY AWARD: (5) Irwin Hochberg, (6) Mordechai Lebenberg of KNR Constructions Hypothesis represents gifts of $50,000 or more. Query represents gifts of $25,000 or more. For a description of the DRI Foundation's Cycle of Discovery donor award program, please visit www.diabetesresearch.org. 5 | AROUND THE DRI DRI DEVELOPS FIRST EVER “LIVING WINDOW” to View Transplanted Islets For the first time ever,scientists can view transplanted insulinproducing islet cells in realtime. As published in the prestigious journal, Nature Medicine, DRI researchers used a sophisticated noninvasive imaging system to observe how islets develop blood vessels and nerves following transplantation. DRI DISCOVERS IMPORTANT REGULATOR OF BLOOD SUGAR > Continued from Page 1 neurotransmitter which facilitates the release of glucagon. Neurotransmitters are chemicals that relay, amplify and modulate signals between a neuron and another cell. “We learned that glutamate acts as a positive signal that instructs alpha cells to speed up glucagon secretion in order to prevent glucose levels from falling too low,” said Dr. Caicedo. This process prevents hypoglycemia in those without diabetes, as well as in islet transplant recipients. Just how the body regulates the correct amount of glucagon wasn’t clear until now. “It is this signal pathway that is our discovery,” says Dr. Berggren, head of Cell Biology and Signal Transduction at the DRI and head of Experimental Endocrinology at the Karolinska Institutet.“This interaction between beta cells and alpha cells is crucial for normal blood sugar regulation.” The researchers also noted that when beta cells do not produce insulin, the alpha cells’ signal pathways are blocked, which eliminates their ability to respond to changes in glucose. Therefore, in those with type 1 diabetes whose beta cells have been destroyed this entire cell process is hampered. “We are now designing strategies to test the use of the neurotransmitter glutamate, which is critical to this mechanism, to determine if we can prevent hypoglycemia in patients who require insulin,” says Dr. Caicedo. To view a video featuring Dr. Berggren speaking on this novel work, please visit www.diabetesresearch.org. The DRI team, directed by Dr. Per-Olof Berggren from the Karolinska Institutet in Sweden, selected the anterior chamber of a mouse’s eye as a“living window”to monitor islets in a live model. “We chose this unique site because the eye offers a The prestigious journal, Nature virtually unobstructed view Medicine, featured the DRI’s groundthrough the transparent breaking study on the cover, showing the image of an islet (in red) engrafted cornea,”explained in the anterior chamber of the eye, with Dr.Alejandro Caicedo from the dense blood supply to the islets the DRI’s Islet Physiology lab. (in green). “By implanting islets in the eye, we are able to follow the same cells over time and assess their function as well as the immune system’s response to the transplanted cells.” This novel viewing platform gives researchers unprecedented opportunity to observe the effects of new drugs on islet engraftment, function, regeneration and their ability to prevent rejection. “Until now, scientists had no way of directly viewing and monitoring the biological processes of islets upon implantation,” explained Dr. Camillo Ricordi, scientific director of the Diabetes Research Institute. That’s because in clinical trials islets have been infused into the liver, making it impossible to view their activity in real time.The liver,which is easier to access than the pancreas,provides a rich network of blood vessels.However,similar to their native environment in the pancreas, islets are scattered throughout and deeply embedded in the organ. The Islet Physiology team is continuing these studies and exploring the potential use of the eye as a transplantation site for pilot clinical trials. DRI Presents Results of Continuous Glucose Monitoring Study Investigators from the DRI’s Clinical Islet Transplant Program showed that the use of continuous glucose monitoring systems (CGMS) in islet transplant recipients can provide important data to assess how the transplanted cells are working. In recent years, improved technology has provided clinicians and patients alike with the ability to monitor blood sugars around the clock in‘realtime’. Rather than a snapshot of a single blood sugar reading or a three-month average with a Hemoglobin A1C test, multiple readings per hour are able to plot patterns and impact regimen changes. In a study conducted by DRI researchers, CGMS was used to assess metabolic control in 25 patients with type 1 diabetes, including 12 who had previously received islet transplants.The participants were monitored for three consecutive days and repeated every three months during the 18 month study. “We found the continuous glucose monitoring system to be useful in telling us how well our patients were doing after their islet transplant,” said Lisa Gorin, DO, a third-year fellow in endocrinology, diabetes and metabolism at the Diabetes Research Institute.The results were presented at Mastering Your Diabetes is a unique educational program for people with diabetes and their families. Participants of diverse ages, professions and nationalities overwhelmingly report that MYD is a life-altering experience for them... MASTER YOUR DIABETES THROUGH INNOVATIVE DRI PROGRAM Insulin therapy is essential for life in those with type 1 diabetes and is an increasingly required therapy for people with type 2 diabetes. Perhaps there is no other condition that requires so much diligence and proactive management on a minute-to-minute basis to achieve normal blood sugar control. To provide the level of knowledge needed to accomplish this, the DRI has designed an empowering diabetes self-management program, Mastering Your Diabetes (MYD), which is a unique educational and experiential program for individuals using insulin therapy and for their family members or significant others. This comprehensive five-day program provides insulin management education and the necessary tools to make informed decisions about blood glucose interpretation, insulin management and the factors that influence diabetes control, all with the purpose of promoting a flexible lifestyle and optimizing health outcomes. One of the keys to the success of MYD is the unique perspective brought by each participant. So while MYD is a group-based program, it ensures achievement of individual needs. Participants of diverse ages, professions and nationalities overwhelmingly report that MYD is a life-altering experience for them, providing unique opportunities to interact with others with diabetes and explore their self-management decisions in a supportive team environment. Participation provides a better understanding of how blood glucose levels respond to various lifestyle and therapeutic changes, assisting participants in developing improved problemsolving skills and the ability to live more confidently and with greater flexibility. has gained a newfound knowledge of diabetes and his ability to control blood sugar. He has regained physical well-being and selfconfidence and now feels in control of his life. In fact, he wants to help others gain that same control. “I have felt an extremely strong urge to help other diabetics that are in the same place that I was in prior to attending the MYD class.” (To read a letter from Todd, please visit the Mastering Your Diabetes area of our website at www.diabetesresearch.org/DiabetesEducation&Management) The expert education team is led by Dr. Luigi Meneghini, director of the DRI’s Kosow Diabetes Treatment Center, and is comprised of nurse practitioners, nurse educators, dietitians, psychologists, and endocrinologists. The interactive and experiential components of the MYD Program include daily review of personal blood glucose records, insulin management options, activities to enhance proficiency in carbohydrate counting and opportunities for participants to explore and express the impact of diabetes on their lives. Participants receive comprehensive education and medical evaluation prior to the start of the course. During the program, laboratory test results are reviewed as a way to teach standards of diabetes medical care. This review also enhances skills for improved patienthealth provider interactions. MYD is offered four times a year, and program participants benefit from regular follow-up, support, and annual updates on state-ofthe-art scientific advances. For more information, please contact Arleen Barreiros, the DRI’s education coordinator, at (305) 243-3696 or visit www.diabetesresearch.org. Todd Dunnahoe, a recent MYD participant from Texas, wrote, “Prior to attending the MYD class, I felt hopelessly out of control, like there was nothing I could do to change anything. The MYD class has completely changed my life.” Todd, like many other MYD participants, the American Association of Clinical Endocrinologists 17th Annual Meeting & Clinical Congress. Dr. Gorin was recognized for her oral presentation receiving First Prize at the conference. CGMS can be a useful tool as an indicator of islet graft function and the metabolic effects of islet replacement therapy. “We found that those participants who had undergone islet transplantation had significantly fewer episodes of hypoglycemia throughout the study period,” said Gorin.“They also spent longer periods of time in the normal glycemic range with overall improvement in glucose control and metabolic stability. “We hope that with the use of real time continuous glucose monitoring we can better predict islet graft function, thus allowing us to intervene earlier in the disease process,” Gorin concluded. The Clinical Islet Transplantation Program is currently screening individuals for participation in a new islet transplant trial.This trial is part of the National Institutes of Health (NIH) Clinical Islet Transplant Consortium (CIT).The new trials are aimed at extending long-term islet function and improving anti-rejection drugs. 7 | UNDER THE MICROSCOPE with Alessia Fornoni, M.D., Ph.D. Type 1 diabetes is an autoimmune disease in which an individual’s insulinproducing beta cells are mistakenly destroyed by his/her own immune system.While the actual cause of this autoimmune attack is still under investigation, researchers are uncovering a number of key factors that lead to the onset of the disease. In recent years, scientists have discovered that chronic inflammation plays a major role in islet loss. DRI researchers are now testing numerous anti-inflammatory agents to prevent islet destruction while exploring how the different cells that make up the Islets of Langerhans function. These cell clusters are responsible for regulating and maintaining normal blood sugar levels. A better understanding of the factors that lead to beta cell loss and contribute to normal beta cell function will help in developing strategies to restore natural insulin production in those living with diabetes. Scientists are identifying many of the key molecules involved in islet function. Among these is nephrin, a promising new therapeutic target. Nephrin, derived from the Greek nephros, or kidney, is a substance essential for optimal kidney filtration, which eliminates toxins produced by the body, as well as for the retention of certain molecules needed for a person’s survival. Although nephrin was thought to be a kidney-specific molecule, scientists recently discovered it in the pancreas, where its actual role still needs to be fully understood. However, recent findings suggest that there is a link between the development of type 1 diabetes and nephrin, thought to be a target of autoimmune attack. At the DRI, Dr. Alessia Fornoni, assistant professor of clinical medicine in the Division of Nephrology and Hypertension, and her colleagues have generated preliminary results showing that beta cells express nephrin and that this molecule is vital for beta cells to secrete insulin in response to blood sugar. In diabetes, nephrin expression in the kidneys is reduced, which contributes to the development of diabetic kidney disease. Dr. Fornoni has demonstrated that this decrease of nephrin is also seen in beta cells of patients with diabetes. To further investigate this connection, Dr. Fornoni and her team are using mice, lacking nephrin in the pancreas, to assess the protein’s potential to prevent type 1 diabetes and also to delay the need for insulin injections in those with type 2 diabetes. Q. How does your research fit in to the DRI’s cure-focused mission? A. Evidence that both type 1 and type 2 diabetes are chronic inflammatory states led me to study the function of novel antiinflammatory agents for the treatment of diabetes. Inflammation affects the ability of insulin to signal through its own receptor and to maintain proper cell function and survival. If we overcome insulin’s inability to signal, we can recover islet survival, function and viability after exposure to inflammatory stimuli. We have generated preliminary evidence that this could also be the mechanism by which nephrin facilitates islet cell function. Ensuring effective insulin signaling and maintaining proper islet cell function is probably one of the best ways to go about finding a cure. Q. Can nephrin facilitate the development of insulin-producing cells? A. Nephrin expression is critical for mature kidney cell development. Knowing this, we are planning studies in collaboration with DRI’s stem cell development team to explore the role of nephrin in the generation of insulin-producing cells from immature cells known as precursors. Q. What brought you to the DRI? A. I obtained my M.D. and Ph.D. in Medical Pharmacology at the Universita’ degli Studi di Pavia in Italy. I later joined the Renal Cell Biology lab in the Vascular Biology Institute at the University of Miami Miller School of Medicine. I continued my medical education at UM, where I currently work as a clinical nephrologist treating many diabetic patients. After being appointed assistant professor in clinical medicine at UM in 2005, I had a strong desire to join a research institution committed to curing diabetes, and I was very fortunate to have the opportunity to join the DRI team. I’ve always thought of diabetes as a slow but persistent “Pac Man” that will slowly take over patients’ bodies and souls. Here, my training and research successes in diabetes and diabetic complications can be quickly translated from the lab to patients. The commitment of the DRI’s scientific director, Dr. Camillo Ricordi, to finding a cure and his ability to harness talent from multidisciplinary areas of expertise are among the DRI’s biggest strengths and was a major reason for my joining the institute. Q. How does this multidisciplinary environment benefit your research efforts? A. At the DRI, my interaction with cell biologist Dr. Per Olof Berggren is critical to characterizing the role of nephrin in insulin secretion. The enthusiasm and encouragement of Dr. Ricordi; expertise of immunologists Drs. Luca Inverardi and Alberto Pugliese; intellectual support and technical assistance of Dr. Antonello Pileggi and molecular biologist Dr. Ricardo Pastori; as well as mentoring of physician scientists, such as Dr. Daniel Mintz, will be instrumental in finding a cure. I also have a close interaction with Dr. Jochen Reiser, recently recruited from Harvard Medical School to become chief of nephrology and hypertension at UM; Dr. Peter Mundel, basic science research director of UM’s Division of Nephrology; and Dr. Karl Tryggvason, the scientist who discovered nephrin in the kidney. I’m excited about the recruitment of researchers with different scientific backgrounds and believe this strategy will be pivotal in leading to new discoveries. Q.What are your future research plans and how will that help find effective treatments? A. I believe that understanding and improving beta cell function is necessary for finding a cure for diabetes. By knowing more about how beta cells work, we can develop strategies to better preserve islets and protect cells from the dangerous effects of anti-rejection drugs, inflammatory agents and the immune system. Nephrin is probably just one of the pieces of the puzzle but, once the puzzle comes together, a cure will be found. My patients are the driving force of my research. Help, Heal, Inspire and Inform THE BENEFITS OF ONLINE COMMUNITIES What the DRI Foundation’s PEP Squad (Parents Empowering Parents) has discovered through its outreach to “diabetes families” across the country is that several newly diagnosed kids and parents feel isolated in their local communities. There are countless cases where the child is the only one with diabetes at the school, and the family has no one to turn to for advice or simply an understanding ear from someone in the know. Many families, however, have already discovered that online communities, social networks and web logs (blogs) bring the global diabetes community to your living room (or wherever your PC/laptop might rest!). One of the first online diabetes communities that emerged and that continues to be one of the most trusted diabetes resources on the web is ChildrenWithDiabetes.com (CWD). Founded by Jeff Hitchcock in 1995, the site offers a thriving support system and allows families to share experiences and connect with each other. “As a parent of a now young adult with type 1 diabetes, I am very optimistic about my daughter’s future. Throughout the world, many doctors and scientists are working very hard to unlock the secrets of type 1 diabetes,” said Jeff, who created the site in response to his daughter’s diagnosis at the age of 2. “Until the day that type 1 is no longer, Children with Diabetes helps families and kids to live well with diabetes. Together, as a community, we learn and share and offer support.” In 2000, CWD held its first conference for 110 families who gathered for camaraderie and fun. Today, the conferences have grown to become the most amazing educational and support experiences for families who have kids with diabetes. The Diabetes Research Institute and Foundation have been involved since the very first year, and at the 2008 Friends for Life Annual Conference in July, which attracted more than 3,000 people, the DRI’s Dr. Norma S. Kenyon and Dr. Cherie Stabler gave informative presentations for both parents and kids. What has quickly become the coffee shop of the 21st century is the online social network, a place “where everybody knows your name” - or user name where you can go to connect with others, socialize and exchange ideas. And no, parents, it’s not just for your teenagers! There’s a social network out there for everyone: saving time in our busy lives, allowing us to meet others with similar interests, and offering one-on-one contact as our own schedules permit. Two very popular diabetes social networks are TuDiabetes.com, where users write blog posts, exchange ideas in discussion forums, and share photos and helpful videos, and Diabetestalkfest.com, which is dedicated to live scheduled chats with medical professionals, scientists and nutritionists and also live daily chats to help connect people with diabetes coast to coast. These sites encourage users to discover new people and new possibilities; they turn distant strangers into friends with a click of the mouse; and they provide access to a variety of people with diabetes from around the globe. Support Our Work While Doing Yours Many companies encourage employees to support charitable organizations through workplace giving campaigns. These gifts are tax deductible and can be made through a payroll deduction program. Simply select the DRI Foundation from your company’s charitable choices and encourage your co-workers to do the same. If the Foundation is not already an option, you can further assist by working with us to determine how to go about being included. For participants in the Combined Federal Campaign (CFC), our number is #11149.We are also listed under the Health 1st America’s Charities Federation. The easiest way to find us is in the alphabetical index at the back of your campaign guide. If your company holds a United Way campaign, you have the opportunity to contribute to the DRI Foundation by utilizing the write-in feature. Please call 1-800-321-3437 or email [email protected] if you have any questions. Be Entertained & Educated Online In recognition of National Diabetes Awareness Month, the DRI Foundation will run its first online webathon throughout November to raise funds and awareness.Offering entertainment as well as education on diabetes and the DRI, the webathon will feature online auctions, play-for-the-cure tournaments, healthy lifestyle segments, comedy acts, messages from celebrities, and much more! Linda and Barry Gibb will serve as International Hosts, and Larry the Cable Guy, Sugar Ray Leonard, Roy Firestone, Lance Burton, Smokey Robinson, and Bret Michaels have already signed on to lend their talent. Tune in to www.DiabetesWebathon.com for updates! Other great online resources are diabetes blogs, such as Amy Tenderich’s DiabetesMine.com and Scott’s Web Log by Scott Strumello (sstrumello.blogspot.com). A popular on-line interactive diabetes site, dLife.com offers comprehensive information directed toward empowering those with diabetes, their familiy members and other caretakers. These sites and others offer personal accounts and life stories, different perspectives on the latest tools, technologies and scientific research, information on variety of diabetes management issues, plus the opportunity for readers to review and respond. Most of all, online communities allow you to learn, connect, help, heal, inspire, inform and relate. Don’t delay in getting involved. To find out about additional online resources, visit www.diabetesresearch.org/links. To get connected to a PEP Squad member, find the link on our homepage or call 1-800-321-3437. 9 | LET ME COUNT THE WAYS TO GIVE There are so many different ways to contribute to the Diabetes Research Institute Foundation. Below is a short list of easy ways to give and we have additional ideas posted on our website. Visit diabetesresearch.org/Foundation, then click Ways to Give, Generous Partners or Links. Honor and Memory Gifts Looking for a unique way to show that you care? Keep the memory of loved ones alive or honor someone special for a birthday or milestone. The Foundation will notify that individual or family member and send you a confirmation of your thoughtful gift. Call 1-800-321-3437 or visit the above web link. Online Giving – At no cost to you! The DRI will receive a donation just from you doing the things you do every day. • Shop online at GiveBackAmerica.org • Use GoodSearch.com as your preferred online search engine • Plan your wedding at IDoFoundation.org • Donate your car through Cars4Charities.org Generous Partners The DRI Foundation has partnered with multiple companies that offer enjoyable products and donate a portion of their sales to support the DRI's cure-focused research. • Drink VitaZest® if you love vitamin and fruit enriched water – drinkvitazest.com • Rejuvenate at Canyon Ranch, Skana or Miraval Resorts if you love spa destination get aways – [email protected] • Order the Swingdicator to improve your golf game – swingdicator.com • Enjoy HoneyTree’s Sugar Free Imitation Honey – honeytreehoney.com Shown here with DRI Scientific Director Camillo Ricordi, M.D., Kelli Klein (right) and her mother, Marci, were impressed by their tour of the DRI and are thrilled to support the DRI with Dog Tags 4 Diabetes. THE FUTURE OF PHILANTHROPY What does the future of philanthropy look like? Could it possibly resemble a boy band and its fawning tween fans? In the case of one young philanthropist helping to forge the way for her generation, it does! Currently rampant among teenage girls nationwide, OJD is defined in the urban dictionary as Obsessive Jonas Disorder, a frenzied fascination with everything relating to pop-rock stars, the Jonas Brothers. For 16-year-old Kelli Klein, the affliction provided the ideal market audience for the perfect fundraising opportunity, one which combines the love of her favorite band with her desire to help cure one of its members. A huge fan of the Jonas Brothers for about two years, Kelli has attended several of their shows, keeping track of Kevin, Joe and Nick Jonas via the Internet in between. As she watched the New Jersey siblings rise to superstardom, Kelli also witnessed OJD sweep the nation…and a metaphorical light bulb turned on. When the Jonas Brothers performed at the DRIF’s Carnival for a Cure in New York City in March of 2007, Nick, the youngest brother, revealed that he has type 1 diabetes. Since then, millions of fans all over the world have watched the video taken at the event. It was in this way that Kelli learned about the DRI and realized her desire to help support its work toward a cure. And when she noticed Nick wearing a medical ID tag and realized that his fans would want to wear one in support of him, she put her thoughts into action. With a business mind beyond her years, the high school student excitedly described her plan to her mother. They ordered samples of dog tags from various vendors, chose one, and purchased 100 dog tags engraved with the words, "Support Diabetes, Support Nick." Kelli then created MySpace and Facebook pages, which she named “Dog Tags 4 Diabetes.” Immediately, she began receiving orders for the dog tags and soon she was thrilled to deliver her first check for $800 to the DRI Foundation. And as of now, Kelli’s project has raised more than $6,500 for the DRI. “I am so proud of how far Dog Tags 4 Diabetes has come, and I hope the success continues,” Kelli said. Referring to the Jonas Brothers’ title track from their upcoming album, out August 12, she continued, “I strongly believe if we work together, Nick and the millions of others dealing with diabetes will only have to wait A Little Bit Longer for a cure.” If every kid was doing what Kelli is doing, we’d have a cure! This is the future of philanthropy. JOIN US AT DIABETES 2.0 New Venue! New Format! DIABETES 2.0 Harnessing New Technologies in Research and Treatment What’s next in diabetes research and treatment? What’s available now? Is it hype – or hope? The 7th New York Research Update will answer these questions and more on Saturday, October 25, at the Marriott Marquis in New York City. For an agenda of the daylong conference and to pre-register, visit www.diabetesresearch.org. ENJOY HONEYTREE’S SUGAR FREE IMITATION HONEY AND SUPPORT THE DRI Most folks love the good, sweet taste of honey. Now, people with diabetes and those looking to reduce their sugar intake can also enjoy this delicious treat with HoneyTree's Sugar Free Imitation Honey. To sweeten the deal, HoneyTree, Inc., a top quality honey supplier with a 90-year history, donates a portion of product sales to the DRI. The Diabetes Research Institute Foundation and HoneyTree, Inc., recently announced this new partnership that indicates the honey manufacturer’s commitment to supporting the cure-focused work being conducted at the DRI. The Foundation logo will appear on the label of HoneyTree’s Sugar Free Imitation Honey to help consumers easily identify a great-tasting alternative. 1 IT ALL ADDS UP “More and more adults – and parents – are taking a proactive role in their family’s healthful habits and specifically nutrition. Small changes in diet, such as reducing sugar intake, can make a huge impact, especially for people with diabetes or who are at risk of developing diabetes,” said Robert A. Pearlman, president and CEO of the Diabetes Research Institute Foundation. “We are grateful for HoneyTree’s support of our mission to cure diabetes and for their concern for all people affected by this disease.” Consumers can find HoneyTree’s Sugar Free Imitation Honey and other HoneyTree products in select grocery stores and drug stores nationwide, or they can order directly from the company’s website, www.honeytreehoney.com. With its golden color, smooth honey-flavored taste and thick, flowing consistency, HoneyTree’s Sugar Free Imitation Honey is the ultimate honey substitute. It can be used in place of honey in recipes, as a topping for toast, breads and cereals, or as a sweetener in tea and coffee. DIABETES DIPLOMATS DEMONSTRATE: A sweet-tasting substitute for those who love honey. “HoneyTree is pleased to have an opportunity to give back to the diabetic community. We are privileged to support a research focused organization such as the DRI Foundation in its efforts to find a cure for diabetes,” said Bob Olney, HoneyTree’s president. 2 3 1. Sammy Schechter proudly presented DRIF’s Jill Shapiro Miller with a check, signed by his entire 2nd grade class. 2. Shannon Painter (center) coordinated The Benefit in Chicago in honor of her friend, Alyssa LeVine (right.) Also pictured is Alyssa’s husband, Cory LeVine. 3.(l-r) Lorraine, Carol, and Michal Nudelman plus Morton Blumberg, support the DRI with hope of a cure for Ashley Blumberg. As the prevalence of diabetes rises, so does the amount of people who have a connection to the disease. When these individuals act upon the desire to “do something” for themselves or on behalf of their loved one with diabetes, then colossal results are achieved. Following are just a few examples of Diabetes Diplomats of varying ages and geographic locations who are showing that it all adds up for the DRI. Recently diagnosed with type 1 diabetes, 8-year-old Sammy Schechter helped his parents, Beno and Rosa Schechter, produce a DVD of Beth Am Day School’s 2nd Grade Chanukah Celebration Show, which he offered to his classmates for a donation. Sammy was deeply touched and amazed as he opened the envelopes and saw the amounts contributed by his classmates. Beating his goal of $1,000 by a landslide, Sammy was excited to present “a big fat check” for $5,575.50 to the DRI. In response to his father’s gentle warning that the money may only last 15 minutes in the DRI's labs with such expensive equipment, Sammy said,“Who knows…maybe just like in Chanukah, the miraclecure could be found in those 15 minutes and last for a life-time.” While Sammy and his classmates were busy in Florida, another Diabetes Diplomat, Shannon Painter, was hard at work in Illinois. In honor of her friend, 27-year-old Alyssa LeVine, who was diagnosed with type 1 at age 6, Shannon coordinated The Benefit, held at Level nightclub in Chicago on April 19. More than 200 guests attended the trendy event, sipping cocktails and nibbling on sushi as they enjoyed music spun by popular deejays. The evening peaked with a fabulous spring fashion show, featuring the work of top designers. Proceeds benefited the DRI, and thanks to Shannon, awareness of the DRI reached additional Midwesterners. Even further west, in Colorado, Carol Nudelman, along with her husband, Morton Blumberg, and her father, 92-year-old Michal Nudelman, were spreading the word of the DRI to another group of people. Motivated by 18-year-old Ashley, Carol and Morty’s daughter who has been dealing with type 1 diabetes for seven years, they began a letter writing campaign in 2002. Each year, the campaign has raised approximately $20,000 for the DRI. While Carol initiates the effort, Morty helps her to fine tune and personalize each letter, and they send them out to family and friends across the country. Michal personalizes his own letters and reaches out to his and his wife, Lorraine’s friends and family.“Just as polio was eradicated in our lifetime, so can juvenile diabetes become a historical footnote,” their letter expressed this year. As efforts across the country are combined, it is clear that it all adds up when you are an advocate of the DRI. Please contact the DRI Foundation at 800-321-3437 if you would like to become a Diabetes Diplomat to raise funds and/or awareness for the DRI. You can also send an email to [email protected] or visit www.diabetesdiplomats.com for more information. 11 | ARMANI EXCHANGE SUPERMODEL STEPS OUT FOR THE DRI Proving that giving never goes out of style, supermodel Izabel Goulart, along with Armani Exchange, raised $10,000 for the DRI in just two hours on May 3 in New York City. Starring in the Armani Exchange (A/X) Spring 2008 advertising campaign, the Brazilian beauty greeted her fans at the SoHo A/X store, graciously autographing her photos and handing out DRI information. “I am here with all my love to raise money for the Diabetes Research Institute,” Izabel said. “I am 100 percent positive that one day they’ll find the cure.” DRI Foundation President and CEO Robert A. Pearlman was on-site to present Izabel with a certificate of appreciation for her support of and dedication to the cause, one that is as close to her heart as it is to so many others. Supermodel Izabel Goulart, new friend of the DRI. “This is such an honor for me,” the 23-year-old sensation said earnestly. “I have someone in my family who suffers from diabetes.” Izabel’s 7-year-old brother was diagnosed with type 1 diabetes five years ago. Since then, she has worked with hospitals in her native Brazil to raise money to provide free insulin for diabetic children in need. Upon hearing of the DRI, Izabel expressed her belief that the message was a Godsend because she sincerely wants to find a cure. More than just an angel to the DRI, Izabel has been a Victoria’s Secret “Angel” since 2005. She has sashayed down the runway wearing duds by top designers such as Bill Blass, Oscar de la Renta, Valentino, Chanel, Michael Kors, Ralph Lauren and Stella McCartney, among others. She also had her television debut last year in an episode of HBO’s Entourage. The DRI looks forward to a lasting relationship with Izabel Goulart, a woman whose beauty is not just skin deep. DIAMOND ANNIVERSARY, CRYSTAL BALL More than 400 guests gathered at the Garden City Hotel for the 10th anniversary of Long Island’s premier DRIF event, the Crystal Ball. According to Gala Committee Chairman Charles Rizzo, the elegant affair, held on May 3, raised $792,000. The tremendous success of the event can be attributed in part to the dedicated support of the evening’s honorees, Jodi and Michael Genatt, and the recipients of the Gillin Family Humanitarian Award, Michael’s parents, Judy and Les Genatt. The family has taken on the search for a cure as a personal mission ever since Jodi and Michael’s 15-year-old son, Zach, was diagnosed with type 1 diabetes five years ago. “Diabetes affects the entire family. It changes your whole life,” said Jodi, personally thanking everyone in the room for their attendance and support. “It’s going to take a facility like the Diabetes Research Institute down in Miami to find a cure for this disease. With the money we raise here tonight, we will find a cure,” added Michael. During the dinner program, which was led by WCBS-TV’s Dr. Max Gomez, DRI Associate Director Dr. Norma Sue Kenyon explained some of the research underway. She further connected with the crowd by discussing her personal sense of urgency as a scientist and a mother of a teenager with type 1 diabetes. Touched by her words, the audience responded with generous gifts during the Fund-A-Grant portion of the program, including significant contributions from the Future Leadership Foundation, Roberta and Bruce Waller and Family, Martin Granowitz, the Genatt Family and Genatt Associates, Inc., and Joan and William Fishlinger. Other top sponsors included Wright Risk Management; Congdon, Flaherty, O’Callaghan, Reid, Donlon, Travis & Fishlinger; The Weitz Family Charitable Foundation/Weitz & Luxenberg Law Offices; ACE INA Foundation; AIG Insurance Companies; Kenneth and Jane Hirsch and the Seaman Family Foundation; and Rooms to Go Children’s Fund. The Grand Ballroom was transformed into a sophisticated supper club thanks to Lawrence Scott Events, the producer and underwriter of the evening's design and decor. Thanks to the Kossoy, Auerbach and Landow families, guests went home with a variety of goodies, such as beautiful pashminas, limited edition frosted glass water bottles handcrafted with Swarovski Crystals, and Crystal Ball tote bags. 1 1. Honorees Michael and Jodi Genatt (left) with their son, Zach, and Judy and Les Genatt, Gillin Family Humanitarian Award recipients. 2. Gala Committee Chairman Charles Rizzo, and his wife, Marie. 2 NEW ENGLAND PATRIOTS' VINCE WILFORK'S MANTRA: ONE LIFE TO LIVE Considered one of the finest defensive tackles in the NFL today, New England Patriots’ Vince “Big Daddy”Wilfork is also a fine example of a son who took his father’s words to heart. Vince’s philanthropic actions, as well as the tattoo on his upper arm, reflect the mantra of David Wilfork, Sr.: One Life to Live. For more than half of his 26 years,Wilfork witnessed his father struggle with complications of diabetes. In 2002, while he was attending University of Miami, he sadly received news that his father and best friend had lost this battle. And since then, Wilfork has bravely turned his heartache into an ongoing fight for life. “I am trying to help find a cure for diabetes so that maybe one day I can prevent a son or daughter from losing their mother or father to the disease,” Wilfork said. Organized by his wife, Bianca, and supported by friends, family and teammates, including Randy Moss, Ty Warren, Kevin Faulk, Santonio Thomas, Pierre Woods, Lonnie Paxton, Logan Mankins and Ellis Hobbs, Vince Wilfork’s 5th Annual Draft Day Fundraiser was held on March 15 at PiNZ in Milford, MA. More than 800 fans from throughout New England and across the Eastern Seaboard attended the party, eagerly anticipating the chance to interact with their favorite nose tackle while watching the draft on three gigantic projection screens and a multitude of televisions. Guests were treated to professional draft Vince and Bianca Wilfork raised more than $100,000 for the DRI with their 5th Annual Draft Day fundraiser. commentary, while enjoying food, drinks and raffles, plus live and silent auctions. PlayStation’s Madden and bowling tournaments kept the fun rolling. Proceeds exceeded $100,000 this year, more than double from last year and ten times the amount the first event raised, when Vince himself donated half of the $12,000 proceeds. The DRI is grateful to call Vince and Bianca Wilfork, along with their son, D’Aundre, and daughter, Destiny, friends and partners in the quest to cure diabetes. Don’t miss out on this wonderful family’s 6th Draft Day fundraiser, which is certain to be even bigger and better than ever! Don Strock Diabetes Classic CELEBRATES A SILVER ANNIVERSARY Presented by Miami Seaquarium and supported largely by the produce industry, the Don Strock Diabetes Classic attracted 175 golfers to Miccosukee Golf and Country Club on May 14, raising more than $175,000. In honor of the 25th annual tournament, fellow current and former pro-athletes Dan Marino, Dwight Stephenson, Nat Moore, Jim Jensen, Larry Little, Don McNeal, George Mira, Kim Bokamper, Harvey Clayton, Tony Fiorentino, Eddie Hill, Quadtrine Hill, Ricky Jackson, John Harris, and Twan Russell joined Don Strock on the course. “Dan Marino was a rookie the first year we had this tournament,” Strock quipped. “That gives you some perspective on just how long we’ve been doing this.” After enjoying perfect weather on the course, the spirited group tackled cocktails and dinner, plus live and silent auctions. When seven special guests took the stage, silence overcame the noisy dining room. “My little brother is a hero,” said Emilio Lamar, Jr., age 13, speaking of 11-year-old Felipe, who has type 1 diabetes. “He has to be much more responsible than other kids. And he never complains.” With maturity beyond their nine years, Brooke Miller displayed the bulky diabetes-related contents of her purse and Hunter Cope explained how her diabetes dog and constant companion, Diva, senses when her blood sugar is too high or too low and then alerts one of her family members. Brooke’s mother, Lynette Miller, shared further examples of how the disease affects the whole family. Matthew Sanchez, Ellie Tamminga and Armand Guim also addressed the teary-eyed crowd, and the universal hope of all children with diabetes was summed up in ten words:“My dream is just to be a regular kid again.” “You’ve just heard firsthand the reason for this tournament,” said Barbara Singer of the DRI Foundation. “With our help, these kids can look forward to a future free from diabetes.” Bruce Fishbein, event chairman since inception, then announced with pride that the Classic’s cumulative proceeds have now surpassed the $2 million mark. Generous sponsors: Back (l-r) Tournament Host Don Strock, Chairman Bruce Fishbein of The Produce Connection, Terry Willie of Miccosukee Tribe of Indians of Florida, name unavailable. Middle (l-r) John Spicei of Taylor Farms of Florida, Jim McGrath of Outback Steakhouse, Andrew Hertz of Miami Seaquarium, a representative of Tropical Shipping, Mike DeGiuseppi of Minuteman Press of Boca Raton, John Marini of Heineken USA, Floyd Seskin of Uro-Club, Jeff Pfaff of Top Tomato, Adam Homan of Six L’s Packing Company, and Morris Corbitt of The Produce Connection. Front (l-r) Doug Tannehill of C.H. Robinson Worldwide, Paula Pippin of Coca-Cola, Robert Piper and Jerry Share of Sheds Plus, and Bruce Schumin of M & R Produce Distributors. Not pictured: American Fruit & Produce, Miccosukee Championship, Florida Mushroom, Freedom Fresh, Sierra Produce, The Oppenheimer Group, Capital Produce Distributors, Crystal Springs and Warren Henry Automobiles. 13 | EVENTS LONG ISLAND REGION Springing Forward More than 350 women attended Spring into Fashion, presented by Roberta and Bruce Waller and Family, at the Carlyle on the Green in Bethpage State Park. A decade ago, dear friends Addy Fritzhand (2nd from left) and Miriam Marlowe-Shiff (right) started the event, and this year they were honored for their dedication as co-chairs. The elegant luncheon was followed by a fashion show featuring the spring collection, provided by Marshs. Honorary Chairman Senator Craig Johnson and DRI’s Gary Kleiman were on-hand to congratulate current Co-chairs Doreen Peykar (2nd from right) and Rina Weinbrom (left) on a successful event, which raised $214,000. In Heart & Mind The family of Helaine Shari White continues to celebrate her incredible love of life and powerful spirit with fundraising events that focus on laughter, fun and family. Her parents, Rhoda and Donald White, and her two sisters and brothersin-law, Peter and Hillari Boritz and Renee and Ron Spiegel, organized the eighth annual Lanie's Lanes at the East Meadow Bowling Lanes. Keeping Lanie in heart and mind, the family raised more than $28,000 for the DRI this year. Pictured bowling are Marti Motherway and his granddaughter, Caitlyn Bella. EMPIRE BALL Another Empire Record The 2007 Empire Ball, which was chaired by Peter DiCapua, was held at the Grand Hyatt Hotel and raised more than $1.4 million. Sponsored by the Real Estate Division of the DRI, the event had another record breaking year, attracting more than 1,200 guests. The gala honored Edward Piccinich (center), executive vice president of SL Green Realty Corp, who received the prestigious Empire Ball Award from last year’s honoree, David Arena (left) of Grubb & Ellis. (Also pictured is Marc Holliday, CEO of SL Green Realty Corp.) The Camillo Ricordi Humanitarian Award was presented to John Catsimatidis, chairman and CEO of Red Apple Group, Gristedes Supermarkets, by last year's recipient, Arthur Skelskie of Moody’s Corporation. The annual DRI film was emceed by Patti LaBelle, and the evening’s entertainment was provided by the Ric Mango orchestra and the Mid Life Crisis band. What’s Cooking? Glen Cove Mayor Ralph V. Suozzi and Judge Richard McCord were among the guests of the fifth annual Cooking for a Cure dinner prepared by Page One Restaurant’s co-owner and chef, Jeanine DiMenna. Held at and sponsored in part by Page One, this exquisite dinner raised $45,000, which included a generous $25,000 grant secured by Senator Carl Marcellino. The event honored Jean Corrigan RN, CDE (2nd from left), director of the Pediatric Diabetes Program at Winthrop University Hospital. Also pictured (l-r) are Co-chair and DRIF Long Island Regional Board member Delia Whitton, Long Island Regional Board Chairman Allan L. Pashcow, Co-chair Mary Hall, and Long Island Regional Director Anthony E. Childs. Shooting for a Cure Featuring an exciting day of clay shooting, the third annual Sportsmen for Charity (SFC) event was held on April 18 at the Pawling Mountain Club in Pawling, NY. Event Chairman Charles F. Guigno and SFC President Edward A. Rytter thanked approximately 80 guests for their participation during the awards program. Guigno made special mention of his connection to diabetes, as he displayed confidence in the DRI. Guigno is pictured (left) with his grandsons, 10-year-old Joseph, and 17-year-old Michael (right), who was diagnosed with type 1 diabetes at age 11. UNION EVENTS Labor of Love In sunny San Diego, the 23rd annual Labor of Love Golf Tournament brought together nearly 200 members, friends and business associates of the labor unions at Steele Canyon, one of Southern California’s finest golf clubs. Las Vegas Convention and Visitors Authority sponsored a welcome cocktail party Friday evening at Hotel Del Coronado, and the dinner program Saturday evening was held at this gorgeous Victorian landmark on Coronado Island. Special thanks were extended to Harbaugh Hotels for donating the crystal door prizes once again and to Harrah’s Entertainment for making a $50,000 donation to the event, which raised nearly $200,000. Hosted each year by the Building and Construction Trades Department (BCTD) of the AFL-CIO and led by President Mark H. Ayers, Labor of Love is an integral part of the Blueprint for Cure campaign, which to date, has raised approximately $40 million for the DRI. Pictured are BCTD Secretary/Treasurer Sean McGarvey (left) and BCTD President Emeritus Ed Sullivan. 15 | EVENTS NORTHEAST REGION Dare to Dream DRIF’s Northeast region proudly held its third annual D.R.E.a.M.S. in the City fundraiser on May 14 at Cipriani 23rd Street in New York City. The glamorous and sophisticated event attracted nearly 600 people and generated close to $1 million. Co-chaired by Samantha Shanken, Bonnie Inserra and Risa Pulver, vice chairman for events and public relations of DRIF’s Northeast Board, the unforgettable soirée boasted an Art Deco theme. It featured classic cocktails, plus a delicious dinner paired with highly-rated wines, and luxury silent and live auctions. During the dinner program, Michael Strahan of the Super Bowl-winning New York Giants presented Honoree Thomas P. Silver of Orda Management Corporation with the Dare to Dream award. Pictured with Silver is his wife, Natasha Silver, Honorary Chair. Riedel Shows it’s All in the Glass A select group of guests was treated to a unique wine-tasting experience at the beautiful Riedel glass showroom on New York City’s Madison Avenue. Tenth-generation glassmaker Georg Riedel conducted an interactive glass appreciation seminar, during which guests tasted wine in glasses designed for specific types of wine. At the end of the evening, each guest received the set of four beautiful and unique glasses, courtesy of Northeast Board Chairman Ricardo Salmon and his wife, Leslie Dezer, and Northeast Board member Samantha Shanken (center). Attendees were treated to a discussion on advances in diabetes research by DRI’s Dr. Norma S. Kenyon (far right). Also pictured are (l-r) DRI Foundation’s National Board Chairman Emeritus Marc Goodman, National Board Chairman Thomas D. Stern, and President and CEO Robert A. Pearlman. Katya at Carnegie Making history as the first female solo pianist to grace the stage of Carnegie Hall for a record ten breathtaking performances, Katya Grineva (pictured) dedicated her tenth performance on April 27 to children afflicted with type 1 diabetes. More than 1,000 concert-goers enjoyed the evening, which featured the works of Chopin, Debussy, Albeniz, and Ravel. Thanks to the generosity of Platinum Sponsor Monster Worldwide and Gold Sponsor Novo Nordisk, $20,000 of the proceeds from the concert benefited the DRI. World renowned, Katya has shared her musical gift with presidents, dignitaries and the poorest citizens in countries throughout the world. FLORIDA REGION A Decade of Decadence At the tenth anniversary of Pleasures of the Palate, hosts Sue (pictured) and Doug Gallagher welcomed approximately 120 fellow bon vivants to the event’s latest venue, Emeril’s Miami Beach. Guests were greeted with glasses of bubbling champagne and passed hors d’oeuvres before sitting down to a fourcourse dinner paired with the appropriate wines to enhance flavors. Renowned harpist Roberto Perera entertained guests throughout the evening affair, which was presented by Wine Spectator. Exclusive bottles of wine from the cellars of South Florida’s elite collectors were highlighted in the incredible live and silent auctions. Though the wines always take center stage at this event, sharing the spotlight were the perfectly prepared courses served by the impeccable staff at Emeril’s, led by Bryan Kazee (left) and Chef Brandon Benach (right). Third Time’s a Charm Held at the Metropolitan Pavilion in New York City, the third annual Carnival for a Cure raised more than $500,000 for the DRI while supplying nearly 1,000 guests with a fun, family-friendly afternoon. Party-goers enjoyed various foods and the “way cool” tunes of DJ Scott Zuckerman, plus games and activities galore. Some laughed with stilt walkers, clowns, balloon artists and face painters, while others raced sports cars and dunked hoops. All were delighted with fantastic prizes. Co-chairs Robert and Joanne Schenker are pictured with their sons, Michael (center) and Jamie (right). CALIFORNIA REGION Fore! Baseball Great Don Baylor (2nd from left) and Emmy® Award Winning Sports Journalist Roy Firestone joined 200 golf enthusiasts at the Diabetes Research Institute Golf Classic, which was held on May 12 at the El Caballero Country Club in Tarzana. The fourth annual event featured an afternoon of golf followed by auctions and a dinner program that honored Charles Delle Donne (2nd from right), a seasoned veteran of the investment management business. According to Co-chairs Ken Bernstein (left) and Bob Bills (right), the tournament raised $232,000 for the cure-focused work of the DRI. ONLINE AUCTION Priceless Gift for Son with Diabetes As the mother of a child with type 1 diabetes, bestselling author Brenda Novak used the creativity and vision she calls upon regularly as a writer to create the 4th Annual Online Auction to Benefit Diabetes Research. Held throughout the month of May in honor of Mother's Day, the auction offered a unique array of items, such as the chance to appear as a character in Novak’s next novel, personal meetings and mentoring from top-notch, celebrated authors, autographed books, evaluation opportunities with some of the most powerful and wellconnected agents and editors in publishing, and possibly face-to-face interaction with these A-list publishing industry giants. This year, Novak donated approximately $70,000 to the DRI, the newest beneficiary. Novak is pictured with her 11-year-old son, Thad, who was diagnosed with type 1 diabetes at age 5. A Family’s Commitment The fourth annual DRI Golf and Tennis Classic boasted outstanding weather and equally sunny, hopeful spirits at Miami Beach’s prestigious La Gorce Country Club on Monday, January 28. More than 300 friends of Chairfamily Javier (far left), Andria (3rd from left), Matthew (not pictured), Nicole (right) and Andrew (2nd from left) Holtz, turned out to show their support and encouragement for the family’s ongoing efforts to help the DRI find a cure for their youngest member, Andrew. Ever since he was diagnosed with type 1 diabetes seven years ago at age 7, it has become the personal mission of everyone in the Holtz household to do anything possible to eliminate the disease. In accordance with their great efforts, each event, including this one, has raised more than $350,000. 17 | EVENTS FLORIDA REGION Dance, Romance and Family Ties In its 34th year, the Love and Hope Ball truly became a family affair for International Chairmen Linda and Barry Gibb (center) when their children, (l-r) Ashley and Therese, Travis and Stacey, Michael, Ali, and Stephen and Gloria Gibb, were named the first Young Society of Love and Hope Honorees. Other VIPs graciously thanked by Life Chairman Sonja Zuckerman were: Humanitarian Honoree Sherman Simon, Honorary Chairmen Serena and Leon Simkins, Love Honoree Shirley Harris and Hope Honorees Carmen Alexander Printup and Michael Alexander. Golden Beach Police Chief Jim Skinner then presented the key to the town of Golden Beach to Executive Chairmen Sandra and Sid Levy. Themed An Evening of Dance and Romance, the black-tie gala, which hosted more than 500 guests, was held at the Westin Diplomat Resort & Spa on February 16. In combination with the Love and Hope Preview Party in November, the fabulous evening once again raised more than $1 million. Ladies Shuffle and Shop More than 220 women gathered to support diabetes research while enjoying an afternoon of card games and boutique shopping at Polo Club of Boca Raton, for the Ninth Annual A Gift of Love…A Gift of Hope Luncheon. Once again led by Mariana Sherman (right) and Renee Aronin (left), the ladies of the Palm Beach County Auxiliary organized the event, which raised more than $30,000, their largest amount yet, for the DRI. If you would like to help out with or attend the next A Gift of Love...A Gift of Hope event, please call the DRI Foundation at 800-321-3437. Stepping Up to a Cause Approximately 1,000 students, teachers, and parents, walked, ran, biked and skated to the finish line of the Seven-mile Walk-a-thon. The pinnacle of DRI Week, a week-long campaign that allows participants to organize projects of their choice to create awareness and raise funds for the DRI, the walkathon was held at C.B. Smith Park in Pembroke Pines. This year, it was organized by Charles W. Flanagan High School senior Matt Caesar, who oversaw the work of not only the members of his own National Honor Society (NHS) chapter, of which he serves as the Parliamentarian, but also of all the other participating NHS and National Junior Honor Societies in Broward County. Pictured with Caesar (2nd from left) are classmates (l-r) Jack Garcia, Tony Guadamuz and Keith Brown. DRI Week was also recognized on February 18 with a Majic 102.7 live broadcast with Vance Phillips at the Rand Eye Institute in Pompano Beach. D'Vine Divas Dish it Out for Diabetes Serving as a kick-off for the 2008 Food Network South Beach Wine & Food Festival and celebrating the talents of some extraordinary women, the D’Vine Divas dinner was held at the Biltmore Hotel. Female chefs from coast to coast prepared each course, which were paired with incredible wines, courtesy of Southern Wine & Spirits. This fun, feminine and flavorful event also featured live and silent auctions, which benefited the DRI. Pictured are Hosts Samantha Shanken (center) of Wine Spectator and Master Sommelier Laura DePasquale (right), with Yvonne Robert of the Biltmore Hotel Cellar Club. Welcome to the Jungle Jungle Safari intertwined elegance and exuberance to create one of the most memorable events of the area’s famed equestrian season. This decidedly-different gala, held at the International Polo Club Palm Beach on March 1, was topped off with a safari-themed ambience. Aside from the human guest list, which surpassed 300, partygoers were delighted to spend time with a white tiger, a Bengal tiger and a black leopard, as well as a young kangaroo, ring-tailed lemurs and a tiger cub. Chairmen Joe and Ashley Maguire (pictured) were pleased to announce that the event raised more than $225,000. They offered special recognition to their sponsors and committee, as well as to Honorary Chairmen Joan and Lou Jacobs, Chairmen Emeritus Karen and Bob Cavanagh and Vice Chairmen Debbie and Mark Plaxen, Ginny and Paul Farber, and Marie and Michael Bianchini; and Presenting Sponsor U.S. Trust - Bank of America Private Wealth Management. Seeing Stars On the heels of another successful fundraising season, members of Love and Hope were thanked for their tireless dedication and support at the committee’s season-closing event, the Thank You Luncheon, held at Miami’s Westview Country Club. Life Chairman Sonja Zuckerman (left) and Executive Chairman Sandra Levy (right) led the program. The coveted Star Award, which is bestowed annually to the person who stands out among the extremely dedicated committee, was then presented to Jill Rosenhaus (2nd from right). The lovely afternoon closed with a serenade by Australian singer and committee member Noeleen Batley Stewart, friend of International Chairmen Linda (2nd from left) and Barry Gibb. Extinguishing Diabetes On March 29, South Florida firefighters took a break from fighting fires to help extinguish another menace to their communities, type 1 diabetes. Consisting of firefighters from several local municipalities, the self-named hockey team, East Coast Bomberos, took on Florida’s West Coast Firefighters in an afternoon amateur hockey game played at the Bank Atlantic Center. According to Dade County Firefighter Bob Maloney, event coordinator, the effort raised more than $12,000 for the DRI. Maloney is shown with his niece, Madison Armstrong, and his nephew, Ryan Maloney, both of whom have type 1 diabetes and were his inspiration for the fundraiser. Fashionably Philanthropic The Young Society of Love and Hope, in conjunction with Saks Fifth Avenue Bal Harbour, Just Cavalli, and Ocean Drive magazine, hosted a hip fundraiser on April 17 at the prestigious Rubell Family Collection in Miami. Throughout an extended cocktail hour, guests indulged in the delectable hors d’oeuvres of Table 8 South Beach and assorted spirits compliments of Roberto Cavalli Vodka and Southern Wine and Spirits. Randi Caster shared her experiences as a DRI islet transplant patient. Then, the runway came to life, and models captivated the audience with a presentation of the Just Cavalli 2008 Fall Collection. Members of the Young Society of Love and Hope include: Therese Gibb, Jamie Jo Harris, Melanie Herman, Andrea Kasparoff, Erin Newberg, Michelle Rubell, and Nicole Simkins. Shown with DRIF President and CEO Robert A. Pearlman are Rubell (left) and VP and GM of Saks Fifth Avenue Bal Harbour Deborah Slack (right). 19 | For information on the events or to make reservations, please call one of the DRI Foundation offices listed below. CALENDAR Rod Gilbert DRI Golf Classic August 4, 2008 / LONG ISLAND To be held simultaneously at two locations, Pine Hollow Country Club and Muttontown Country Club, this event includes an afternoon of golf followed by an awards dinner and silent auction. Phil Peterson’s Key West Poker Run September 19-21, 2008 / FLORIDA Phil Peterson will once again host his annual motorcycle run that starts in Miami and finishes in Key West for South Florida’s biggest biker party weekend of the year. Kids Party for a Cure October 19, 2008 / LONG ISLAND This afternoon of fun for the entire family at Dave and Buster’s will feature video games, inflatables, face painting and more followed by dinner and a silent auction. DRIfocus New York Research Update October 25, 2008 / NEW YORK This day-long conference at the Marriott Marquis will feature scientific presentations and interactive sessions. Stand Up for a Cure October 26, 2008 / CALIFORNIA Drew Carey and the Improv AllStars will bring down the house during another hilarious night, to be held at the Millennium Biltmore Hotel in Los Angeles. This event includes a cocktail reception, dinner, live and silent auctions and fabulous prize drawings. Diabetes Research Institute Harold Kart Golf Classic November 17, 2008 / FLORIDA An afternoon of golf followed by a cocktail reception and awards dinner will take place at Boca West Country Club. Love and Hope Preview Party November 19, 2008 / FLORIDA In its 35th year, this fabulous dinner reception, which is often referred to as “the heart of Love and Hope,” will officially kick off the group’s fundraising season at the Diplomat Country Club. Kids Party for a Cure November 23, 2008 / FLORIDA To be held at the Miami Hilton Downtown, this fun family event themed Around the World will feature exciting activities, live entertainment, food, a silent auction, raffles and more. Encore! A Cure! January 18, 2009 / FLORIDA Attendees will experience a special showing of the World Premier of Miami Bombshells,The Musical, at Actors Playhouse on the Miracle Mile in Coral Gables after enjoying a light dinner, wine reception and auction. DRI Golf & Tennis Classic January 26, 2009 / FLORIDA An afternoon of golf and tennis tournaments at La Gorce Country Club in Miami Beach will be followed by a cocktail reception and awards dinner. Love and Hope Ball February 7, 2009 / FLORIDA To be held at the Westin Diplomat Resort & Spa in Hollywood, this extraordinary affair is certain to delight its guests while commemorating 35 years of success A Gift of Love...A Gift of Hope February 16, 2009 / FLORIDA Organized by the ladies of the Palm Beach Auxiliary, this tenth annual event will feature a delightful lunch, a unique boutique filled with fashionable items, a raffle, and an afternoon of card-playing at The Polo Club in Boca Raton. is a publication of the Diabetes Research Institute Foundation. Summer 2008 / Volume 36, Issue 1 Staff Lori Weintraub, APR Lauren Schreier Natasha Norris Laurie Cummings Contributors Jeanne Antol Krull Erica Banyon Gary Kleiman Alegre Levy Jill Salter Jill Shapiro Miller Mitra Zehtab, M.D. Design Franz Franc Design Group Inc. DRIfocus Photography Andre Chow Charles Eshelman Fifth Avenue Digital Orlando Garcia Dennis Goldensohn Marc Levine Tony Lopez Lucien Capehart Photography Paul Lester Photography Patty Daniels Town & Country Studio Peter Richardson Sarah Merians Photography & Co. John Seberg Jon Simon Von Kantor Photography & Design Claude Zick Diabetes Research Institute National Foundation Office 200 South Park Road Suite 100 Hollywood, FL 33021 www.diabetesresearch.org address service requested The Diabetes Research Institute Foundation supports the Diabetes Research Institute at the University of Miami Leonard M. Miller School of Medicine, whose mission is to develop and rapidly apply the most promising research to treat and cure those now living with diabetes. To obtain additional information or request copies of DRIfocus, please call (800) 321-3437 or e-mail [email protected], or visit www.diabetesresearch.org. DIABETES RESEARCH INSTITUTE FOUNDATION National Office 200 South Park Road, Suite 100 Hollywood, FL 33021 Phone: (954) 964-4040 Fax: (954) 964-7036 [email protected] Northeast Regional Office 381 Park Avenue South, Suite 1118 New York, NY 10016 Phone: (212) 888-2217 Fax: (212) 888-2219 [email protected] Long Island Regional Office 410 Jericho Turnpike, Suite 201 Jericho, NY 11753 Phone: (516) 822-1700 Fax: (516) 822-3570 [email protected] California Regional Office 6624 Melrose Avenue Los Angeles, CA 90038 Phone: (323) 857-0080 Fax: (323) 857-1856 [email protected] Non-Profit Org. US Postage PAID Diabetes Research Institute Foundation