jr carlson laboratories, inc.

Copyright 2002, 2000, 1999, 1996, 1991
J.R. CARLSON LABORATORIES, INC.
NATURAL and SYNTHETIC VITAMIN E
DIFFER IN SEVERAL WAYS...
Natural
VS.
synthetic
NATURAL-SOURCE
SYNTHETIC-SOURCE
Natural-Source Vitamin E is from
vegetable oils.
Synthetic-Source Vitamin E is from
petroleum or turpentine.
Carlson Natural-Source Vitamin E is derived from soybeans.
All products test GMO-FREE
ABSORPTION & RETENTION:
Scientists have found Natural* Vitamin E is absorbed better from our
digestive system than Synthetic* Vitamin E and retained in the body longer.
Research scientist Maret Traber’s work indicates that the liver preferentially recycles the natural form of
vitamin E (d-alpha tocopherol), causing the excretion of synthetic forms and other tocopherols.
CHEMICAL DIFFERENCE:
Natural*
NATURAL VITAMIN E is the single molecular
configuration which occurs in nature. It is called:
• d-alpha tocopherol
• d-alpha tocopheryl
• rrr-alpha tocopherol
d-
SYNTHETIC VITAMIN E is a mixture of
8 molecular configurations, 7 of which
only occur when made by man.
It is called:
• dl-alpha tocopherol
• dl-alpha tocopheryl
• all-rac alpha tocopherol
dl-
Synthetic*
MORE IN THE BODY CELLS:
Dr. Graham Burton, associated with the National Research
Council of Canada, studied the body’s response to Natural
Vitamin E compared to Synthetic Vitamin E. This study
strongly indicates the body prefers Natural Vitamin E to
Synthetic Vitamin E. Here are some of the results:
❖
❖
❖
❖
❖
❖
5.3 times more Natural Vitamin E
was found in the Brain than
Synthetic Vitamin E and:
3.6 times more in Red Blood Cells
2.6 times more in the Lungs
2.4 times more in the Plasma
1.9 times more in the Heart
1.7 times more in the Muscles
This published study measured the
proportion of Natural and Synthetic
Vitamin E in various organs, tissues
and fluids of experimental animals
given equal doses of both types of
Vitamin E. The preference was then
confirmed by measurement of Vitamin E
in blood and plasma from human
subjects. This study was based on
equal milligram amounts, not IU
amounts, which tries to correct for
some of the differences observed.
Our
Our bodies
bodies know
know the
the difference!
difference!
The International Unit [IU] System For Vitamin E
Potency “Has Not Been An Exact Science.”
The International Unit System for Vitamin E was designed to account for all of the
potency difference between Natural and Synthetic Vitamin E so that 1 IU of
Natural Vitamin E would be equivalent to 1 IU Synthetic Vitamin E. However,
there is scientific evidence which challenges it. As Max Horwitt, Ph.D., indicates
“. . . the standardization of the various tocopherols for their biological values has
not been an exact science.”
The IU system is based on a type of Synthetic Vitamin E which has not been
commercially manufactured since 1956. The form had 2 molecular spacial configurations,one of which does not occur in nature. The present Synthetic Vitamin E
has 8 molecular spacial configurations, 7 of which do not occur in nature.
But can the International Unit System, even if revised, show all the differences?
Or will our bodies still favor the Natural-source Vitamin E and continue to show
higher tissue levels, better absorption and longer retention?
Some researchers, such as Jeffrey Bland, Ph.D., have questioned whether spacial
configurations of tocopherol found only in Synthetic Vitamin E are actually a
hindrance to the body because they tie up receptor sites, preventing the
naturally occurring form of Vitamin
E from acting. This is like someone
In this Brochure:
putting the wrong key into a lock.
The right key cannot open a lock
NATURAL Vitamin E means Natural-Source
when the wrong key is in it.
SYNTHETIC Vitamin E means Synthetic-Source
*
E
E
OTHER FACTS YOU
SHOULD KNOW ABOUT
VITAMIN E . . .
Vitamin E is ESSENTIAL to life. We can not survive without it.
Several prominent researchers believe that to perform at its best,
the human body needs more than the U.S. Daily Value (DV)
of 30 IU Vitamin E daily.
The average American diet
supplies considerably less than this amount.
E
Dr. Evan Shute, a Canadian physician internationally recognized for his 30
years of work with Vitamin E stated, “We think that the average normal female
should have 400 IU a day and the average normal male about 600 IU a day.”
E
Vitamin E should be taken at mealtime. Dr. G.E. Desaulniers of the
Shute Medical Clinic has shown that Vitamin E is absorbed better
when taken with meals rather than on an empty stomach.
Inorganic IRON can destroy VITAMIN E. The Shute Institute was
the first to discover and announce that inorganic iron, as ferrous
sulfate, can be destructive to the Vitamin E when the two are
taken together. They suggest that when inorganic iron and Vitamin E are
taken, they should be separated in the stomach by an interval of 8 to 9 hours.
E
Organic iron, however, such as that found in raisins, spinach and other ironrich foods, can be taken at the same time as Vitamin E, with no harm to the
Vitamin E. Moderate amounts of organic iron supplements, such as the
“Albion process” iron amino acid chelate, can also be taken with Vitamin E.
E
NATURAL VITAMIN E is stated as:
E
SYNTHETIC VITAMIN E is stated as:
ddl-
• rrr-alpha tocopherol
• d-alpha tocopherol
d-alpha
tocopheryl
acetate
•
• d-alpha tocopheryl succinate
• all-rac alpha tocopherol • dl-alpha tocopherol
• dl-alpha tocopheryl acetate • dl-alpha tocopheryl succinate
Some firms mix 10% Natural Vitamin E
with 90% Synthetic Vitamin E and call
their product NATURAL VITAMIN E
without declaring the synthetic portion. The
U.S. Food and Drug Administration (FDA) has
yet to act to stop this misleading labeling.
E
Deceptive product labeled
“Natural”
c
10% Natural
Vitamin E
i
%
90 nthet E
Sy amin
Vit
To be sure your Vitamin E is 100% Natural Vitamin E and not a blend
containing mostly synthetic Vitamin E, choose only products that print the
following on each bottle label:
E
Two biologically active, preferred forms of Vitamin E are:
d-alpha tocopheryl acetate and
d-alpha tocopheryl succinate
Acetate and Succinate are important organic molecules within our bodies
and are involved in numerous biochemical reactions. For example, acetate
is an important part of acetylcholine, the neural transmitter required by
every nerve cell in our bodies to transmit impulses. Moreover, acetate and
succinate are found in energy producing reactions in every cell. Acetate is
another name for vinegar, and succinate is 2 acetic acid molecules attached
together.
Because these two forms change to alpha tocopherol during the digestive
process, they are active antioxidants.
E
All forms of Natural Vitamin E become active antioxidants
(free radical fighters) inside our bodies.
The ALPHA form of tocopherol is considered Vitamin E. Beta,
Gamma and Delta tocopherols, often called mixed tocopherols,
have less Vitamin E activity in the human body. Alpha and mixed
tocopherols are present in substantial amounts in Carlson E-GEMS PLUS.
E-Gems Elite contains alpha and mixed tocopherols, with the related
tocotrienols.
E
E
E
Natural Vitamin E penetrates the skin and is of benefit to some
skin conditions. It can help keep your skin looking young.
All Carlson Vitamin E Products Test GMO-free.
A Personal Word about
Natural Vitamin E
from Susan Carlson
Beginning in 1946, Canadian physicians Evan and
Wilfrid Shute pioneered and documented Vitamin E therapy,
using it on over 30,000 patients at the renowned Shute Institute
and Medical Clinic.
Initially they had only crude wheat germ oil to use as a
Vitamin E source, followed by Synthetic Vitamin E. When
Natural Vitamin E became available, Doctor Evan Shute
discovered it was more effective for his patients. He found
Vitamin E useful for so many conditions that other physicians
and scientists became suspicious about this powerful nutrient.
Today, medical research continues to
substantiate the numerous clinical findings of Doctors Evan and Wilfrid Shute.
Like many brilliant pioneers, they were
ahead of their day, discovering uses of
Vitamin E only now being rediscovered
and substantiated. Sadly, both did not
live to see these newer advances.
We were introduced to Vitamin E
through the Shute Institute of Canada.
The results we observed when using Vitamin E were
exceptional, yet even then we noticed significant differences
when using Natural Vitamin E as compared to its Synthetic
version. We even experienced differences between the different forms and brands of Vitamin E. Because our optimum
health depended on only the finest Vitamin E, we decided to
provide it ourselves and began planning a new company.
When Carlson Laboratories became a reality, we were
committed to offering only the highest quality Vitamin E
which would consistently provide the best results. We were
convinced then, as now, that Natural Vitamin E is superior to
Synthetic, so ALL Carlson Vitamin E supplements, since our
beginning, have been only 100% Natural-Source Vitamin E.
To assure you of its quality, we print the following guarantee
on every bottle:
The independent testing firms are registered with the FDA as
following Good Laboratory Practices. Assay (test) reports are
available on request.
Look over our Vitamin E products. They are the finest.
If you have any questions on Vitamin E or other nutritional
subjects, be sure to ask us. We are Carlson Laboratories, a
caring family owned company dedicated to serving you.
Yours for health,
Susan Carlson
Registered Pharmacist
Licensed Nutritional Counselor
VITAMIN E GAINS NOTORIETY
FROM SCIENCE
With over 50 years of scientific research,Vitamin E
has gained notoriety as one of the most predominant
and active antioxidant nutrients. The amounts of
Vitamin E effective within clinical studies are not
obtainable, even from a well-balanced diet, and that is
why many people choose a Vitamin E supplement.
100% NATURAL-SOURCE VITAMIN E
Promotes a Healthy Heart and Cardiovascular System
Maintains the Strength of Capillary Walls
Helps Maintain Blood Glucose Levels
Within a Normal Range
Promotes a Healthy
Immune System
Supports Healthy Vision
Promotes Healthy
Nerves and Muscles
100%
Natural-Source
Vitamin E
Protects Other Nutrients,
Including Fish Oils and Vitamin A and C
The statements above have not been evaluated by the FDA.
These products are not intended to diagnose, treat, cure or prevent any disease.
The
Essential
Nutrient
Promotes Healthy
Skin and Hair
Protects Cell
Membranes by
Preventing
Free Radical
Damage
Promotes
Normal
Growth
Helps Maintain
Your Good
Health
Protects Lung Tissue
Carlson
Vitamin E is
Twice as active
in our bodies
as synthetic
Vitamin E
(gram to gram)
Carlson All Natural-Source Vitamin E
is Twice as Active in our Bodies
as Synthetic Vitamin E*
Promotes a Healthy Heart and
Cardiovascular System
Is Necessary for the Proper
Functioning of the Immune System
Protects Cell Membranes by
Preventing Free Radical Damage
Since its discovery, Vitamin E has gained the interest of scientists and health
professionals world-wide. It was originally found that an absence of Vitamin E
caused animals to become sterile. Further research has shown a deficiency of
Vitamin E in some animals may also result in muscular dystrophy, certain heart
problems and other ailments. The most extensive clinical work with Vitamin E
was done by Doctors Evan and Wilfrid Shute of Canada, beginning in the 1940’s.
Because this essential nutrient cannot be manufactured by the body, many
knowledgeable individuals are choosing a Vitamin E nutritional supplement.
E•GEMS®
A Very Popular Product!
E-GEMS are golden gelatin gems containing concentrated natural-source
Vitamin E oil, (d-alpha tocopheryl acetate). The Vitamin E is derived from
soybean oil; synthetic Vitamin E is never used.
8 Strengths
E • GEMS are twice as active
as Synthetic Vitamin E
30 IU
100 IU
200 IU
(Actual Size)
400 IU
600 IU
800 IU - 1000 IU - 1200 IU
“I would like to thank you for your interest in our work and your efforts to market a
good quality vitamin E which we feel confident to recommend to our patients.”
G.E. Desaulniers, M.D.
Medical Director, Shute Medical Clinic, London, Canada
E•GEMS® ELITE
Exclusive Formula
Complete E-Family of Tocopherols & Tocotrienols
E-GEMS ELITE is an exclusive blend of 8 forms of natural-source tocopherols and
tocotrienols providing the antioxidant benefits of the entire family of Vitamin E.
Research supports that natural forms of Vitamin E as found in foods have beneficial
properties playing roles in protecting body cells from free radical damage.
E-GEMS ELITE provides 400 IU of Vitamin E as d-alpha
tocopherol, plus the benefits of beta, delta and gamma
tocopherols and their 4 corresponding tocotrienols.
Each Soft Gel Contains
Vitamin E (as d-Alpha Tocopherol) . . . . . . . . . . . . . . 400 IU
d-Gamma Tocopherol . . . . . . . . . . . . . . . . . . . . . . . . . 100 mg
d-Beta and d-Delta Tocopherol . . . . . . . . . . . . . . . . . 40 mg
Total Tocotrienols . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 mg
Tocopherols & Tocotrienols are from soy, palm and rice oil
concentrates. Typical tocotrienol analysis shows gamma
tocotrienol 13 to 14 mg, alpha tocotrienol 6 to 7 mg, beta and
delta tocotrienols 3 to 4 mg. Natural color. Preservative-free.
TOCOTRIENOLS
Antioxidant
Palm oil provides an all natural-source of alpha,
beta, gamma and delta tocotrienols with 100 IU of
Vitamin E. Carlson Tocotrienols provides the
same ratio of tocotrienols as used in several
scientific studies. Tocotrienols are powerful,
naturally occurring antioxidants closely related to
Vitamin E.
Each soft gel provides 200 mg of palm oil
containing approximately 36 mg to 50 mg of
tocotrienols.
Amount Per Soft Gel
Vitamin E
(as d-alpha Tocopherol)
100 mg
Gamma Tocotrienol
20 to 24 mg
Alpha Tocotrienol
12 to 18 mg
Delta and Beta Tocotrienols 4 to 8 mg
THE RECOMMENDED VITAMIN E
CARRIES THE BEST GUARANTEE
On each Carlson Vitamin E label you’ll find the words:
“Independently Assayed to Guarantee 100% Potency,
100% Natural-Source Vitamin E.”
Carlson does not just promise quality, we guarantee it.
Every batch of Vitamin E product is assayed (tested)
for potency and source by an independent testing
firm who is registered with the FDA as
following Good Laboratory Practices.
Every assay report since our
beginning, like the one
shown at the right,
is available for
viewing at our
Laboratory.
Copies of
individual
assay reports
may be requested.
TESTED
QUALITY
E•GEMS® PLUS
Alpha & Mixed Tocopherols
E-GEMS PLUS are soft, gelatin capsules containing
Vitamin E derived from soybean oil supplying d-alpha
tocopherol plus other tocopherols.
Independent assay results of E-GEMS PLUS show a full
200 IU, 400 IU or 800 IU of Vitamin E in the form of
d-alpha tocopherol, natural and not esterified. Non-alpha
tocopherols are also present including d-beta, d-delta and
d-gamma tocopherols in significant amounts.
3 gths
e
Str
n
(Actual Size)
200 IU
400 IU
800 IU
d-Alpha Tocopherol
Plus
200 IU
400 IU
800 IU
Mixed Tocopherols
34 mg
67 mg
134 mg
(Non-Alpha)
d•ALPHA GEMS™
Highest Concentrate
If you are taking “mixed tocopherols”
and not taking E-GEMS PLUS, you
could be getting only 2 mg of mixed
(non-alpha) tocopherols.
400 IU
(Actual Size)
Tiny, Soy-Free
Soft Gels
Formulated for the renowned Shute Medical Clinic of Canada, d-ALPHA GEMS is
natural-source Vitamin E, so pure it is considered soy-free. Because it is so highly
concentrated (1360 IU/gram), the soft gels are smaller than E-GEMS. Both are
concentrates of d-alpha tocopheryl acetate.
AQUA GEM•E
Water-Solubilized Vitamin E
Before Vitamin E can be used by the body, it must be absorbed by the
digestive system. Vitamin E is a fat-soluble nutrient. Research shows that some
people are unable to absorb the full potency of fat-soluble (oil-based) vitamins.
All of the following can interfere with the
body’s absorption process:
• Digestive Disorders
• Fried Foods
• Illness
• Environmental Toxins
• Dieting
• Alcohol
• Stress
• Age
Aqua Gem-E is Vitamin E from soy, solubilized to
disperse in water to support absorption by the body.
Two Strengths of
AQUA GEM-E:
(Actual Size)
200 IU
400 IU
A
C
E
S
ACES®
Vitamin E teams up with other antioxidant
nutrients to provide protection
from excess free radicals.
Antioxidant Nutrients
ACES provides natural Beta-Carotene [pro-Vitamin A], buffered
Vitamin C, natural-source Vitamin E, and organic Selenium.
Four natural antioxidants are in easy-to-swallow soft gels.
PRO-VITAMIN A (Natural Beta-Carotene) . . . . . . . . . . 10,000
VITAMIN C (Non-acidic Calcium Ascorbate) . . . . . . . . . . 1,000
VITAMIN E (Natural d-Alpha Tocopherol) . . . . . . . . . . . 400
S ELENIUM (Selenomethionine) . . . . . . . . . . . . . . 100
IU
mg
IU
mcg
Provided by two soft gels.
KEY•E® TABLETS
Chewable Dry Vitamin E
KEY-E TABLETS are Carlson’s exclusive formulation containing the naturally dry d-alpha tocopheryl acid succinate form
of Vitamin E, derived from soybean oil. It was our first
Vitamin E product and continues to be very popular.
❥
Highly effective ❥ May be chewed ❥ Pleasant tasting
❥ Mild in the stomach ❥ Vegetarian
KEY•E® KAPS
Dry Vitamin E Capsules
KEY-E-KAPS contain the same dry natural-source Vitamin E
as KEY-E TABLETS; however, the Vitamin E powder is in a
hard gelatin capsule. The capsule may be easily swallowed
with liquid or pulled apart to release capsule contents onto
food. Natural bland taste.
E•SEL™
Natural-Source Vitamin E
and Organic Selenium
Together, Vitamin E and Selenium
play vital roles in quenching free
radicals in our cell membranes. The
Selenium is supplied by selenomethionine which is the primary form
in food.
Two Soft Gels Contain:
Vitamin E (d-Alpha Tocopheryl Acetate . . 400 IU
derived from soybean oil)
Selenium (from L-Selenomethionine) . . . 100 mcg
BODY CARE
Natural Vitamin E for
Personal, Skin & Body Care
ADE® CREAM &
Intensive
OINTMENT Moisturizer
KEY-E® CREAM & OINTMENT
For Softer,
Smoother Skin
ADE Cream is an intensive moisturizing
cream rich in Natural Vitamins A, D and
E. Fragrance-free. Extra Strength.
ADE Ointment softens, lubricates, and
protects. Rich in Natural Vitamins A, D,
and E. Unscented. Extra Strength.
KEY•E Cream is a light,
Natural Vitamin E cream which
moisturizes and maintains
softer, smoother skin.
Fragrance-free.
KEY•E Ointment softens,
lubricates and protects.
With Natural Vitamin E.
Unscented.
E-GEM® OIL DROPS
E-GEM® SOAP
100% Natural Vitamin E
E-GEM SKIN CARE SOAP
gently cleans your skin....
leaving you feeling naturally
refreshed. Free of animal
products. Each golden glycerin
bar contains 1000 IU of Vitamin E
(d-alpha tocopheryl acetate) with 1000 IU of
Vitamin A and a fresh fragrance of lemon oil.
Each drop of E•GEM Oil Drops
contains 10 IU of Vitamin E (d-alpha
tocopheryl acetate) derived from
soybean oil. Apply externally to aid
and soften skin or take orally when
controlled dosages are desired.
Popular squeeze bottle.
E-GEM® CREAM
Moisturizing
Feel the soothing, moisturizing
touch of E-Gem Cream as it
smooths away rough, dry areas
while the natural vitamins and
beauty oils pamper your skin.
Each gram of E-Gem Cream contains Vitamin E
with both Vitamin A and Vitamin D. The rich
formula contains a blend of natural beauty oils to
make you look and feel radiant. Fragrance-free.
Translucent Bar
E-GEM® SHAMPOO
For Healthy, Radiant Hair
E•GEM Shampoo is specially
formulated with Vitamin E
(d-alpha tocopheryl acetate),
Vitamins A & D, Panthenol and
Protein to bring out the natural
highlights in your hair.
pH-balanced at 5.5. Non-alkaline.
Biodegradable. Organic.
KEY-E® SPRAY
KEY-E® SUPPOSITORIES
Easy to Apply & Soothing
Soothing and
Lubricating
Natural Vitamin E in Vegetable Spray.
Each 3 seconds of KEY•E Spray
provides approximately 30 IU
of Natural-Source Vitamin E.
Spray lightly on dry, parched, or
irritated skin due to winter
weathering or exposure to sun.
Each KEY•E Suppository
contains 30 IU of
Vitamin E (d-alpha
tocopheryl acetate)
derived from
soybean oil
in a soothing
base of coconut
and palm oil.
Rectal or Vaginal
KEY-E® POWDER
E-GEM® LIP CARE
Pure Powder
1,000 IU of Vitamin E per tube
Each level 1/4 teaspoonful of
KEY•E Powder supplies
700 IU of Vitamin E (d-alpha
tocopheryl acid succinate)
derived from soybean oil.
E•GEM Lip Care protects lips, aids natural
healing, and applies easily.
Natural-source Vitamin E
is the only ingredient.
Each tube contains 1000 IU of
Vitamin E and Aloe Vera.
Ideal for year-round use.
Light lemon scent.
J. R. CARLSON LABORATORIES, INC.
15 College, Arlington Hts., IL 60004-1985
• 888-234-5656 • 847-255-1600 • FAX: 847-255-1605
• E-Mail: [email protected] • Website: www.carlsonlabs.com
030L
REFERENCES:
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
(partial listing)
Recommended Dietary Allowances. 9th ed. Washington, D.C. National Academy of Sciences.
Human Biochemistry. 5th ed. Kliener & Orten. p. 389.
Organic Chemistry. 3rd ed. Morrison & Boyd. p. 584.
“Vitamin E: A Re-examination.” Horwitt, M.K., Ph.D. Am. J. Clin. Nutr. 29:569-578.
“Absorption and Retention of Vitamin E Com. in Ad. Humans.” Horwitt, M.K., Fed. of Amer. Soc. Exp. Bio. 84.
“Rel. Bio. Values of D-A-Tocopheryl A. & All-Rac-A-Tocopheryl A. in Man.” Horwitt, M.K., Am. J. of Clin. Nutr.
1980. 33:1856-1860.
Vitamin E: A Comprehensive Treatise. Machlin, L.J., Ph.D., Ed. B. and Clin. Nutr., Vol. 1. Marcel Dekker: NY. 1980.
Vitamin E: Biochemistry and Health Implications. Vol. 570. Annals of the NY Academy of Sciences: NY. 1989.
Bjorneboe, A. et al. Absorption, Transport of Vitamin E. Journal of Nutrition. 120:233-242. 1990.
Burton, G.W. et al. “Comparison of Free A. Tocopherol & A. Tocopheryl Acetate...” Lipids. 23:834-840. 1988.
Kayden, H.J. and Traber, M.G. “Absorption, L. Transport & Reg. of Vit. E in Humans.” J. of Lipid Res. 34:343-358. 1993.
Ferslew, et al. Journal of Clinical Pharmacology. 33:84-88. 1993.