Multimodal Preclinical Imaging Solutions

Multimodal Preclinical
Imaging Solutions
The Path to More Advanced In Vivo Research
BioPET/CT™
NanoPET/CT®
MRS 1500™
MRS 3000™
BioPET/CT-XL
BioPET/CT-MR
BioSONIC WAVE™
BioSONIC VIEW™
NanoSPECT/CT®
HiSPECT®
NanoX-CT
Minerve®
InVivoScope™
™
BioFLECT/CT™
™
™
Multimodal Preclinical Imaging Solutions
About Bioscan
Bioscan is totally focused on
preclinical imaging. With a large team
of application specialists, technical
engineers and dedicated sales
personnel, Bioscan doesn’t provide
equipment - we provide solutions. From
advice on setting up your preclinical
lab to post-processing and image
analysis, there will always be an expert
available to assist you with your life
sciences research.
Our Vision
Become the leader in preclinical imaging by:
• Providing best-in-class in vivo imaging systems
in the key life science modalities
• Providing superior applications and technical
support - “Selling solutions, not equipment”
• Building a robust network of direct and indirect
distribution channels to meet demand in a
global marketplace
• Establishing a broad footprint serving the best
research institutions in the world
Our History
Bioscan has supplied customers with unique
research productivity tools for more than 30 years.
Bioscan was founded in 1980 as a supplier of
radioanalytic instrumentation and entered the PET
chemistry equipment market in the late 1990s.
Company Overview
Bioscan is a leading provider of preclinical,
tomographic molecular imaging solutions that
enable groundbreaking life sciences research.
Bioscan’s innovative nuclear (PET & SPECT), optical,
X-Ray CT, Ultrasound and MRI imaging tools are
used worldwide by life sciences companies,
academic institutions and government research
centers to improve their disease, drug discovery
and development research.
With the introduction of the NanoSPECT/CT in
2006 and the NanoPET/CT in 2010, Bioscan set a
new standard in the field of molecular imaging of
animal models for biological & disease research.
In 2011, Bioscan added the BioPET/CT imaging
system to its product line. That year, the company
also divested its analytic instrumentation and PET
chemistry synthesis product lines, focusing the
company exclusively on molecular imaging. In
early 2012, Bioscan launched the BioFLECT true360° tomographic optical imager, as well as the
MRS line of preclinical MRI scanners.
The unique imaging performance enabled by
Bioscan’s patented technologies makes it possible
to translate research protocols and results directly
from animal models of disease to human clinical
trials, enabling faster, more efficient development
of new diagnostics and therapies.
With the recent installation of its first PET/CT/MRI
systems and the introduction of the BioSONIC line
of preclinical ultrasound imagers, today Bioscan
offers the most complete range of preclinical
imaging systems in the world.
Our Mission
Bioscan facilitates early disease diagnosis
and accelerates drug discovery by providing
innovative technologies for preclinical imaging.
Our goal is to provide researchers with reliable,
flexible and easy-to-use instrumentation that offers
state-of-the-art performance capabilities.
Translational imaging from mice to larger animals
5kg
30g
Mice
1
Rats
Marmosets
Rabbits
Monkeys
Uncompromising Performance
Distinctive imaging systems that work in concert
Bioscan provides differentiated, multimodal imaging solutions designed for the preclinical market:
• Sub-mm PET, SPECT and X-Ray CT
• True 360° Optical tomography
• Translational MRI and PET/MRI
• Feature-rich, translational Ultrasound
• Common platforms for Animal Handling & Image Analysis
Features & Benefits:
• Coregistration of multiple modalities made easy - All systems use the same post-processing software
and animal handling equipment.
• Efficiency in your daily research - Modalities can operate simultaneously, so there are no limitations
on research workflow.
• Truly translational - Transfer preclinical study protocols directly to the clinic.
• Wide range of animal models - Accommodates animals from mice to rabbits and monkeys.
• Compact design, small footprint - Bioscan multimodality solutions will fit in imaging facilities as small
as 9m2. The systems are internally shielded and can be installed side-by-side or even back-to-back.
• Upgradable platforms - As your research needs change, upgrade your Bioscan systems to add
throughput and new capabilities.
Multimodal imaging...
BioPET/CT
BioPET/CT-XL
NanoPET/CT
MRS 1.5T &
3.0T
BioSONIC
InVivoScope
Minerve
NanoX-CT
NanoSPECT/CT
BioFLECT/CT
...One common animal handling platform and analysis software
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Bioscan Multimodality Combinations
Superior alternatives to the standard trimodality solution
Researchers interested in pursuing both PET and SPECT imaging often consider purchasing a trimodality
system that combines PET, SPECT and X-Ray CT in a single cabinet. Bioscan has developed solutions for these
customers that rely on two or more discrete systems, because this approach offers significant advantages for
system performance, research efficiency and workflow.
Efficiency Without Performance Compromises
• Better efficiency - Dual systems (e.g., PET/CT and SPECT/
CT) enable acquisitions to be completed simultaneously,
increasing throughput and improving study workflow
• No performance compromises - Achieve industry-leading
performance with each of the modalities you purchase
• Small footprint - Two Bioscan systems can fit in less than 9m2,
less than many trimodality systems
• Upgradable - Bioscan’s modular architecture can enable
you to upgrade your systems to add new modalities or add
throughput
F-18 and Tc-99m
F-18 (FDG):
Heart and
Bladder (Pink)
Tc-99m: Thyroid
and Stomach
(Green)
Research Applications
Small animal imaging - Keys to success
Molecular imaging has become a widely-established procedure for diagnosing various disease states and
monitoring the effects of therapeutic treatments in humans. In recent years, molecular imaging has also
become a valuable preclinical research tool for studying the development and progression of disease in
mouse and rat models, as well as the efficacy of potential therapeutic treatments. Dedicated small animal
imaging systems, which include MRI, PET, SPECT, Fluorescence/Bioluminescence, X-Ray CT, and Ultrasound,
allow for the characterization of biological, molecular and cellular processes in vivo, with exceptional levels of
resolution and sensitivity.
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Oncology
•
•
•
Tumor biology
Metastasis
Therapeutic effect
CNS
•
•
Receptor density
Occupancy studies
Cardiology
•
•
Functional studies
Stem cell repair
Disease Biology
•
•
•
ADME/Tox
•
•
Performance
•
•
•
Sensitivity
Resolution
Uniformity
•
•
•
Flexibility
Anatomical localization
Absolute quantification
Metabolic function
Gene expression
Cell trafficking
•
•
•
Ease of use
Quality Assurance
Throughput
Biodistribution
Time activity curves(TAC)
•
•
•
Standard Configurations
Optional features
Serviceability
Functionality
Productivity
Cost
BioPET/CT™
Small animal PET with sub-mm resolution throughout the FOV
Bioscan offers next-generation LYSO/GSO phoswich technology featuring true Depth-Of-Interaction (tDOI) with
four lines of response, eliminating the degradation of resolution away from the center of the imaging chamber
that results from PET detector parallax effects. The parallax effect is mitigated using information captured as
gammas pass through the double crystal layers, enabling sub-millimeter PET resolution even at the edge of the
field of view. With its thick, dual-crystal layer (15mm: 7mm LYSO + 8mm GSO), the BioPET/CT also provides the
highest sensitivity per axial cm in the industry.
Technical specifications
Cardiac and respiratory
gating
Dynamic & biodistribution
studies - Whole body imaging
High resolution & true
quantification
9 cm
CT specifications:
Dynamic FOV: 68 x 180mm
Detector active area: 120 x 120mm
Spatial resolution: 50, 100, 200µm (Variable)
X-Ray source focal spot: 35µm
X-Ray peak energy: 0-50kv (Variable)
Max Current/power: 1mA/50Watts
18 cm
PET detector specifications:
Crystals: Double-layer 15mm LYSO/GSO
Resolution: 0.8mm
Dynamic axial FOV: 180mm
Axial FOV: 47mm
Transaxial FOV: 68mm
Bore size: 80mm
Abs center point sensitivity @350-700 keV: 3.1%
Timing resolution: 1.5ns
Reconstruction time: FBP ≤ 10 seconds,
2DOSEM ≤ 2 minutes, 3DOSEM <5 minutes
Animals:
Mice, rats, marmosets
BioPET/CT-XL™
Industry-leading digital PET/CT performance...extra-large bore
Finally, a powerful, convenient solution for researchers seeking to perform PET/CT imaging of larger animals.
Featuring a 34cm dual-layer ring of LYSO:Ce crystals coupled to silicon photomultipliers, BioPET/CT-XL’s digital
PET architecture enables uniform, high-sensitivity, high-resolution imaging applications from rabbits to primate
brains. The inline 8-slice X-Ray CT provides an automatic anatomical reference. The optional powered wheels
can transport the system for use in any standard hospital room or research laboratory, while the clinical
package enables dual-use animal and human research imaging.
Technical specifications
PET detector specifications:
Crystal type: LYSO:Ce
Sensor type: SiPM
Subject aperture: 34 cm
Crystal size: 2.3 mm, 20 mm thick dual layer
FOV: 26cm transaxial, 22 cm axial
NEMA sensitivity: 14.5 cps/kBq @350keV
Point sensitivity: 8%
Resolution 2.5 mm
NEC >40kHz (NEMA NU2 2007)
CT specifications:
CT detector: 8x1.25 mm detector
Maximum technique: 140kV 7mA
Detector channels: 3264
Max rotational speed: 60 RPM
Views/second: 1440
Resolution: 0.65mm
Animals:
Rabbits, pigs, cats, dogs, monkeys, primate
brain imaging
Acquisition:
Static & Moving PET acquisition
List mode acquisition
Rebinning: Single slice rebinning
(SSRB), Fourier rebinning (FORE)
DOI native mode
Cardiac & respiratory gating
(optional, available 2013)
Reconstruction:
Filtered Back Projection (FBP)
2D MLEM/OSEM
3D MLEM/OSEM (available 2013)
Portability:
Powered transport wheels (optional)
Self-shielded CT
Human Brain
F-18 AV-133
Human Brain
F-18 AV-45
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NanoPET/CT
®
Sub-mm translational PET imaging
NanoPET/CT uses twelve detector arrays of 81 x 39 LYSO crystals of 1.12 x 1.12 x 13mm3 at a packing fraction
of 92% to ensure PET performance with exceptional spatial resolution. This cutting-edge detector technology
is further complemented by a state-of-the-art data acquisition and processing architecture with 12-bit
high-speed digital to analog converters that fully digitize the detector signals. The NanoPET/CT’s advanced
detection technology and large field of view provide very high absolute sensitivity, together with the flexibility
to image mice, rats and larger animals such as rabbits and monkeys.
Technical specifications
PET detector specifications:
Crystals: 13mm LYSO
Resolution: 0.8mm
Dynamic axial FOV: 300mm
Axial FOV: 95mm
Transaxial FOV: 123mm
Bore size: 160mm
Abs center point sensitivity @250-750 kev: 8.3%
Timing resolution: 1.5ns
Reconstruction: Fast 3DOSEM reconstruction
CT specifications:
Dynamic field of view: 80 x 300mm
Detector active area: 50 x 175mm
Pixel size: 11, 34, 100µm
Focal spot: 9µm
X-Ray peak energy: 35-80kv (Variable)
Max current/power: 180µA/ 8Watts
GPU-based, real-time CT reconstruction
Animals:
Mice, rats, marmosets and rabbits 3kg
High-spatial
resolution system
Mouse thyroid
(F18-NIS)
Dynamic & biodistribution studies Whole body mouse & rats
Rat Brain
(FDG)
NanoSPECT/CT & HiSPECT
®
®
The gold standard multi-pinhole system in preclinical SPECT
Bioscan’s NanoSPECT/CT combines up to four large, proprietary Broadband Gamma Ray Detectors™ with
patented Multiplexed Multi-Pinhole SPECT (MMP-SPECT™) to eliminate many of the sensitivity versus resolution
trade-offs associated with traditional SPECT systems. Unlike any other preclinical SPECT system, Bioscan’s
NanoSPECT/CT offers high-resolution and high-efficiency detection with a large field of view. As a result,
the system can perform fast and dynamic whole-body scans in a single-step procedure, with high isotropic
resolution. The NanoSPECT’s reconstruction software and aperture plates are available separately as the
HiSPECT® upgrade to clinical gamma cameras.
Technical specifications
SPECT Detector specifications:
Detectors: Na(Tl)-Spectroscopy
From 25Kev to 365KeV
Resolution: from 350µm (whole body)
Number of pinholes: up to 64
Stationary, semi-stationary & rotational
imaging
Dynamic Axial FOV: 270mm
Transaxial FOV: up to 230mm (for 5 kg
rabbits)
Bore size: 215mm x 230mm
CT specification
Dynamic Field of view: 80 x 300mm
Detector Active Area: 100 x 100mm
Pixel Size: 50µm
Focal Spot: 9µm
X-Ray Peak Energy: 35-80kv (Variable)
Max Current/power: 180µA/ 8 Watts
Animals:
Mice, rats, marmosets, rabbits (3kg) &
rabbits (5kg)
5
Multi-isotope imaging
e.g. 4 isotopes & CT
Fast Dynamic and Kinetic SPECT (4D-SPECT)
Cardiac and respiratory gating
Tc-99m, I-123, In-111
and Tl-201, plus X-ray
CT
Nanoparticle imaging with nano-liter precision
and pico-molar sensitivity
MRS 1500™ & MRS 3000™
Cryogen-free, superconducting MRI at 1.5T & 3.0T
Our preclinical MRI systems, the MRS 1500 & MRS 3000, are state-of-the-art, cost-effective translational
MRI instruments with low running costs and no special site requirements. The innovative, cryogen-free
superconducting magnets virtually have no fringe field, enabling safe use of the system in any facility and
by any operator. Designed to complement Bioscan’s other molecular imaging modalities, these MRI systems
deliver powerful performance and ease-of-use. The systems feature a small footprint and can be placed within
2m of another imaging system. MRS instruments are in use worldwide for a wide range of life sciences research
applications including, functional, molecular, anatomical and multi-modality imaging.
Technical specifications
Magnet
Magnet type: Cryogen-free, superconducting
Field strength: 1.5T and 3.0T
FOV: 70mm DSV
Homogeneity: DSV 30mm +/- 0.10ppm
DSV 60mm +/- 1.0ppm
Clear bore diameter: 160mm
Example Pulse Sequences
Spin Echo Based Sequences
Fast Sequences
EPI Sequences
Gradient Echo Based Sequences
Magnetic Resonance Angiography
2D & 3D Time of Flight sequence
Bulk Spectroscopy Sequences
IVS Sequences
STEAM spectroscopy sequence
Point Resolved Spectroscopy Sequence
Fat/water suppression sequence
ISIS sequence
Animals:
Mice and Rats
Mouse Sagittal Image; Spin Echo TE 36ms,
Resolution 93 x 93 µ x 1.0mm 1.5T (single
loop surface coil)
Mouse Whole Body Image; Spin Echo TR 1200ms,
FOV 65mm, THK 1.2mm, 3 averages, Scan Time
7m 50s, 130x256, TE = 20 ms
BioPET/CT-MR™
Translational multimodality PET/CT/MRI (1.5T/3.0T)
Bioscan’s entry into the PET/MR imaging segment combines superior PET performance with translational MRI at
1.5T and 3.0T field strengths. Coupling the PET and MRI modalities while retaining superior imaging performance
is a significant technical challenge: As the two modalities are brought into closer proximity, the magnetic field
interferes with the PET detectors, creating a trade-off between field strength and PET resolution. To address the
challenge, Bioscan has developed a three-phase approach* to preclinical PET/MRI development, moving from
sequential imaging to integrated inline imaging and finally to simultaneous/dynamic imaging.
Phase 1 (available today): Side-By-Side PET/CT and MRI
Sequential imaging with the BioPET/CT positioned next to the MRS 1500 or 3000 system.
Sub-mm PET performance, high-resolution, high-contrast MRI at translational field
strengths, seamless integration with PET-CT-MRI compatible animal beds and
automated fusion of PET, CT and MRI images with Bioscan’s InVivoScope software. This
enables both parallel and sequential imaging with the PET, CT and MRI modalities.
MI
SHAM
Phase 2 (Work-In-Progress): Integrated In-line PET/MRI
In-line PET/MRI system similar in configuration to current preclinical PET/CT systems.
This phase will combine magnetic field-tolerant PET detection technology with a
benchtop cryogen-free superconducting MRI system of minimum 3.0T.
Protocol Details: 208 g Wistar Rat
LDA Ligation- chronic infarct SHAM vs. MI
Cardiac Gating: 30 min 18F-FDG uptake
25 min acquistion Dose: 1 mCi
Phase 3 (Work-In-Progress): Simultaneous PET/MRI
New approach to functional preclinical PET/MRI imaging providing sub-mm PET
resolution at fMRI field strengths. Enabled by combining the tDOI technology
from Bioscan’s BioPET detectors with Digital Photon Counting (PDPC**) powered PET
detection.
* Work supported by IMAPPI (ANR - France)
** PDPC= Philips Digital Photon Counting and Digital SiPM Technology (Philips Corporate Technologies, Koninklijke Philips Electronics N.V.)
Digital SiPM: the key to
dynamic PET/MR imaging
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BioFLECT/CT™
True 360° optical tomography with optional integrated CT
With the launch of BioFLECT, Bioscan enables researchers to realize the full potential of in vivo optical imaging.
With BioFLECT’s true 360° tomographic capabilities, researchers will no longer have to choose between
imaging only near the surface of the subject or partial tomography solutions that distort the subject or create
artifacts. BioFLECT provides uniform sensitivity and resolution throughout the subject volume. For the first time,
researchers will be able to examine deep tissue phenomena such as spontaneous tumors and metastases
without sacrificing image quality or quantitative accuracy. With the optional upgrade to integrated, one-pass
X-Ray CT, researchers will gain anatomical correlation data that will significantly improve the segmentation and
resolution of the optical image.
Technical specifications
Imaging performance:
Maximum resolution: ~1mm3
Sensitivity: 800fM/mm3
Uniform resolution and sensitivity throughout
FOV
Field-of-view:
Axial FOV: 100mm (mice), 120mm (rats)
Transaxial FOV: 38mm (mice), 42mm (rats)
Bore size: 45 mm
CT specification
Dynamic Field of view: 50 x 150 mm
Detector Active Area: 115 x 65 mm
Pixel Size: 75, 150, 300 µm
Focal Spot: 18 µm
X-Ray Peak Energy: 0-50 kv (Variable)
Max Current/power: 800µA/50 Watts
Uniform resolution and
sensitivity throughout the
subject
Multimodality imaging
(BioFLECT/NanoSPECT/XRay CT)
Multimodality imaging
(BioFLECT/NanoX-CT)
Animals:
Mice and rats
BioSONIC WAVE™ & VIEW™
Feature-rich preclinical ultrasound with customizable touchscreen interface
The BioSONIC product line offers researchers access to advanced high-frequency ultrasound imaging
capabilities in a package appropriate for today’s challenging funding environment. These compact,
economical systems are fully customizable to support imaging techniques such as harmonic & compound
imaging, plane-wave imaging, panoramic imaging, free-hand 3D imaging, 3D GPS-guided injection & biopsy,
and photoacoustics. The systems’ flexibility enables imaging of mice as well as larger animals with a single,
portable system. Because BioSONIC systems are part of the Bioscan family, users can also gain the advantage
of effortless co-registration of 3D ultrasound data with data from other imaging modalities via InVivoScope.
Technical Specifications
Imaging Modes:
RF collection
B-Mode
M-Mode: Regular, Anatomical, Color
Doppler: Color, Power, Pulsed Wave, Continuous
Wave, Tissue - Triplex
3D freehand registration
4D with mechanical transducer
Contrast imaging - Harmonics & Pulse Inversion
Elastography
Panoramic imaging
Transducers:
Bandwidth/FOV: 14-5 MHz/38mm
Bandwidth/FOV: 40-8 MHz/12mm
Transducer ports: 3(Wave) 2(View)
Data Export:
DICOM compatible, supports export to DICOM servers
and PACS applications
7
Transmit:
Amplitude Maximum: +/- 47V
Channels: 128
Beamforming: Programmable delays, steering
Pulse length: 96 bits@ 80MHz or 40Mhz
Receive:
ADC: 14bits
Channels: 64
Sampling Rate: 40MHz
RF Sampling Max (DAQ): 80MHz
Beamforming: Programmable delays, steering,
dynamic focusing, apodization
Post-Processing Features:
Speckle reduction
TGC, compression, map
Form Factor:
Footprint: 26” x 20” (Wave)
18” x 7” (View)
Mouse
breast
tumor
Mouse
bladder
Mouse
kidney
NanoX-CT™
High resolution, high contrast CT upgradable to PET or SPECT
Bioscan’s NanoX-CT is upgradable to a NanoPET/CT or a NanoSPECT/CT system, depending on the initially
selected configuration. The system acquires X-Ray CT images using helical scanning with volumetric conebeam detection. The NanoX-CT uses a micro-focus source with variable magnification. The combination of
this source with a large bore and detector allow the user to optimize resolution of CT images. Voxel sizes range
from 11-34 microns (<10µm optional) and dynamic axial FOV is 300mm, enabling both microscopy and wholebody imaging applications with mice, rats and larger animals. NanoX-CT’s dedicated GPU allows real-time
reconstruction of CT images.
Technical specifications
NanoX-CT specification
Dynamic Field of view: 80 x 300 mm
Detector Active Area: 50 x 175 mm
Pixel Size: 11, 34, 100 µm
Focal Spot: 9 µm
X-Ray Peak Energy: 35-80 kv (Variable)
Max Current/power: 180µA/ 8 Watts
GPU-based, real-time CT
reconstruction
Animals:
Mice, rats and marmosets
Minerve
®
Pathogen-free multimodality animal handling
Minerve imaging cells provide key support functions to the animal during the preparation stage and
throughout the imaging process. They are compatible and interchangeable with all Bioscan preclinical
imaging systems, including MRI. The Minerve system provides transfer of anesthetic gas, digitally controlled
heating and a pathogen-free environment for infectious or immunocompromised animal models. The imaging
chamber enables precise, repeatable animal positioning. The remote controlled gas and heating control
systems maintain the animal at constant sedation and temperature levels. The imaging chamber includes a
transparent imaging cell and holder and comes in 5 sizes: mouse, rat, marmoset, rabbit and multi-mouse hotel.
One animal handling solution- Five modalities: PET-SPECT-CT-FLECT-MR
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InVivoScope™ Version 2.0
Multimodality image processing software
Bioscan’s InVivoScope (IVS) image processing software features the powerful fully 3D ROI tool developed by
software partner inviCRO. You will be able to classify each individual voxel of a three-dimensional volume
dataset. IVS supports segmentation efforts with an easy-to-use, powerful toolbox for manual, semi-automatic
and fully automatic segmentation. IVS fully supports multimodal and dynamic data. You only have to do the
segmentation for a fixed ROI once and it will be evaluated for all loaded datasets automatically. InVivoScope
supports the import and export of DICOM 3.0 compatible data, as well as providing raw and native image
formats (some with full DICOM conversion). Up to 3 modalities, such as Optical, SPECT, CT, PET or MR, can be
displayed at any time, while even more data can be co-registered, analyzed and modified simultaneously.
One software - Five modalities: PET-SPECT-CT-OPTICAL-MR
Automatic Segmentation
Multi-planar
reconstruction
Comprehensive tools for post-processing
Software Accessories
Software packages to amplify your data
Bioscan offers a spectrum of software accessories and modules to expand your data management,
quantification and analysis. Featured accessories include:
FlowQuant© - A complete cardiac SPECT & PET image analysis package
IVS: Brain Atlas & Quantification Module - Mouse and rat brain models
IVS: 3D Segmentation - Powerful 3D ROI tool
iPACS© - Pre-Clinical Imaging Study Management
Imalytics - Advanced image analysis, quantification, and visualization
FlowQuant
- Tracer kinetic
modeling
- Myocardial Blood
Flow (MBF) analysis
- Myocardial Viability
Analysis
- Cardiac function
using gated image
analysis
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IVS: Brain Atlas &
Quantification
IVS: 3D
Segmentation
- Single-click coregistration routine
- Single-click atlas
deformation routine
- Spreadsheet readout
of radioactivity
- Classify each
individual voxel of 3D
volume dataset
- Powerful toolbox for
segmentation.
- IVS supports 3D ROI
tool
iPACS
Imalytics
- Divide data in
meaningful domains
- Set domain access
policies
- Stores other file
formats, with version
control & electronic
signatures
- Advanced
functionality for
translational research
- Specialized
applications for
pharmacokinetic
modeling, dosimetry
and dementia analysis
Service & Support
Going beyond products... providing solutions
Technical Services &
Support
Field Applications
Support
Bioscan’s technical services and support team
provides exceptional support and service to
Bioscan’s diverse portfolio of small animal, in
vivo preclinical imaging products: BioFLECT/CT,
BioSONIC, BioPET/CT, BioPET/CT-XL, NanoPET/CT,
NanoX-CT, NanoSPECT/CT and the MRS 1500 &
3000.
Bioscan’s Field Applications Scientist (FAS) Team
delivers technical education and training for
Bioscan’s diverse portfolio of small animal, in
vivo preclinical imaging products. These training
sessions are intended to educate the customer in
the expert operation of their new equipment, in
order for them to generate reliable, reproducible
and quantitative results to solve their research
queries of their biological models.
These imaging products are sophisticated,
precision instruments. In order to keep these
instruments operating at their peak productivity
levels, our global network of factory-trained Field
Service Engineers (FSEs) and Field Applications
Scientists (FASs) are available to assist you with
installation, preventative maintenance, calibration,
technical guidance, and emergency repair
services.
We provide fast and knowledgeable support to
ensure your system uptime and performance is
maximized. We also understand that our customers
have their own unique requirements for service,
which is why we offer a variety of service level
agreements. You can select the level of coverage
that best suits your needs.
Bioscan’s support teams are committed to
providing the highest level of onsite and remote
support in the industry with our expert team of
highly trained and courteous staff.
Our onsite training courses, with proven methods
for training and delivery, are guaranteed to
reward the end-user with a successful educational
experience. Each training session is designed
to enable the user to expertly operate his/her
preclinical imaging system. Bioscan has several
on-site training and applications optimization
offerings with the purchase of any new system. In
the event that any customer requires more handson training and/or specialized customization of
acquisition protocols, Bioscan offers additional
customized onsite training packages ranging from
1 to 3 days. These flexible training sessions are
intended to be performed at the customer site. The
training content is developed specifically with the
customer to help customize the training to support
specific areas or applications of interest. If smaller
time frames are required, the FAS Team also offers
hourly remote training sessions using TeamViewer
software.
Bioscan’s FAS Team is comprised of highly trained
and experienced research scientists focused on
education excellence. Our goal is to exceed
customer expectations and satisfaction by
delivering exceptional quality training that is
modality specific and has a measurable impact on
research.
FAS
Team
Sales
Team
Customers
Service
Team
Marketing
R&D
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Multimodal Preclinical Imaging Solutions
Corporate Headquarters
4590 MacArthur Blvd, NW
Washington, DC, 20007 USA
TF: 1-800-255-7226
Tel: 1-202-338-0974
Email: [email protected]
Bioscan Europe, Ltd.
58 Avenue de Wagram
Paris, France 75017
Tel: +33 3 83 63 62 67
Email: [email protected]
NanoPET®, NanoPET/CT®, NanoSPECT®, NanoSPECT/CT®, and HiSPECT® are registered trademarks of Bioscan Inc. Minerve is a registered trademark of Minerve SA. iPACS is a registered trademark of
inviCRO llc, Imalytics is a registered trademark of Philips, FlowQuant is copyright Ottawa Heart Institute. InVivoScope™, MRS 1500™, MRS 3000™, BioPET/CT™, BioPET/CT-MR™, BioPET/CT-XL™, BioCT™, BioFLECT/
CT™, BioSONIC™, BioSONIC WAVE™, BioSONIC VIEW™, NanoX-CT™, Bioscan Inc™ are trademarks of Bioscan Inc. MMP-SPECT is a trademark of Bioscan Inc. under exclusive license from Scivis GmbH.
BioPET/CT is designed and manufactured by Sedecal. BioPET/CT-XL is designed and manufactured by PDSI, Inc. NanoPET/CT is designed and manufactured by Mediso, Ltd. NanoSPECT/CT is manufactured by
Mediso, Ltd. NanoX-CT is manufactured by Mediso, Ltd.. © 2012 Bioscan Inc. All rights reserved.
BioPET/CT patents and applications: ES 2301303, EP 1941835, US 2009213983 and US 20090065699 MMP-SPECT patents: US 7,498,580 - EP 1421411 -US 7,199,371
BioFLECT/CT Patents: US 5,952,664; 6,029,077; 6,044,288; 6,100,520; 6,130,958; 6,150,649; 6,211,512; 6,331,700; 6,681,130; 6,693,287; 6,693,287; 7,155,274; 7,212,848; Plus international equivalents
Rev-AK-08/18/2012
Web:
www.bioscan.com
www.preclinical-imaging.com