program - CardioFocus
Transcription
program - CardioFocus
TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics program The World’s Premier Interventional Experience November 7-11, 2011 The Moscone Center · San Francisco, CA www.tctconference.com Hypertension Innovation Endovascular Innovation Innovating for life. Leading the Way Medtronic is leading the way in interventional medicine. From groundbreaking technologies to novel therapies and more, we’re pioneering a path to the future. For distribution in the USA only. © 2011 Medtronic, Inc. All rights reserved. Printed in USA. 9/11 Transcatheter Valve Innovation Coronary Stent Innovation Table of Contents Overview TCT for Surgeons, Nurses/Technologists, and Fellows ................................. 4 Directors and Organizers. . ........................................................................... 6 Acknowledgements.. ................................................................................... 8 Commercial Support Acknowledgement. . ................................................... 13 Special Activities.. ..................................................................................... 14 ACC and CRF Joint Initiative..................................................................... 16 Learning Labs and Edited Taped Cases..................................................... 18 CME/CE Information................................................................................. 19 TCT 2011 Awards..................................................................................... 20 TCT Week at a Glance.............................................................................. 21 Breakout Symposium II. Working in Today’s Cath Lab. . ........................... 59 Breakout Symposium III. Business Development and Operations.. ........... 59 Scientific Symposia Surgical, Interventional, and Hybrid Procedures (Part 1): Coronary Revascularization. . ................................................................. 59 Peer-Reviewed Research Poster Abstract Sessions. . .................................................................... 60 Challenging Cases Video Abstracts....................................................... 79 Oral Abstract Sessions......................................................................... 82 Scientific Symposia (Continued) Device-Based Approaches for Heart Failure: Recent Developments and New Directions. . ........................................... 88 Faculty International Faculty. . ................................................................................ 24 TCT Advisory Faculty................................................................................ 30 United States Faculty................................................................................ 32 Endovascular Intervention (Part 2)......................................................... 89 Hot Topics in Interventional Cardiology: ACC.11 Highlights for the Interventional, Invasive, and General Cardiologist. . ....................................................... 89 Identifying the High-Risk Patient and Lesion: From Vulnerable Plaque to Ischemia and Viability................................... 90 Live Case Sites and Operators.................................................................. 39 Left Atrial Appendage Closure: Indications, Devices, and Techniques.................................................... 91 Monday Next Generation Drug-Eluting Stents and Bioabsorbable Scaffolds.. ............................................................... 92 Board Review Course with Self-Assessment in Interventional Cardiology (Part 1)........................................................... 42 The Valvular Heart Disease Summit (Part 2): Mitral Valve Therapies........................................................................... 93 TCT for Nurses and Technologists Translational Research and First-in-Human Studies for Emerging Cardiovascular Technologies................................. 93 20th Annual Cardiovascular Nurse and Technologist Symposium............ 42 RCIS Review Course............................................................................ 43 Scientific Symposia Special Sessions Chronic Total Occlusions: Basic and Expert Techniques.. ........................ 43 Endovascular Intervention (Part 1)......................................................... 45 Interventional Innovation: Novel Therapies and The “Best” New Device Concepts for 2011..................................... 46 Left Main and Bifurcation Stenting: An Advanced Operator’s Workshop....................................................... 48 Transradial Angiography and Intervention: From Basic to Advanced. . ..................................................................... 94 Strategies for Cardiovascular Repair: Stem Cells and Beyond................. 49 The Drug-Eluting Stent Summit: Appropriate Utilization of Current Generation Devices............................................... 50 The Valvular Heart Disease Summit (Part 1): Aortic Valve Therapies.......................................................................... 52 PFO and ASD Closure: Evolving Indications, Patient Selection, Devices, and Technique............................................. 53 Special Twilight Sessions Featured Clinical Research I. Transcatheter Valve and STEMI/Heart Failure Therapies............................................... 54 New Patients for New Interventional Therapies. . ..................................... 54 Partnership Session: Angioplasty Summit-TCTAP. . ................................. 55 Evening Programs. . ............................................................................... 146 SCAI ELM Program in Partnership with ACC and CRF............................ 95 Japan-US Synergies for Medical Device Innovation: A Harmonization by Doing (HBD) Educational Symposium...................... 95 Presentation Theater South.................................................................. 150 Special Twilight Sessions Featured Clinical Research II. Drug-Eluting Stent vs. Stent Studies. . .................................................... 96 How to Treat Complex Lesions. . ............................................................ 96 Partnership Session: CIT in Partnership with TCT: Challenging Cases in Clinical Practice................................................... 97 Partnership Session: TCT Russia: Focused Session on Endovascular and Structural Heart Disease.......................... 97 Evening Programs. . ............................................................................... 150 Wednesday Breakfast Meetings............................................................................... 152 Main Arena. . .......................................................................................... 100 How to Treat Theater: Coronary Artery Disease.................................... 101 How to Treat Theater: Endovascular and Structural Heart Disease...... 102 Tuesday 2 Challenging Case Multiplex Breakfast Meetings............................................................................... 147 Challenging Case Theater................................................................... 103 Board Review Course with Self-Assessment In Interventional Cardiology (Part 2)....................................................... 58 International Society-Sponsored Case Theater..................................... 103 Maintenance of Certification (MOC) Course.. ........................................ 104 TCT for Nurses and Technologists Morning Spotlight Sessions Breakout Symposium I. The Great Debates. . .......................................... 58 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Core Training Curriculum in Clinical Research . . ..................................... 104 The World’s Premier Interventional Experience TCT2011 Deep Dive: Stroke Prevention Therapies.............................................. 105 Innovative Surgical Techniques and Technologies................................. 106 International Debating Chamber: Interventional Cardiology on Trial........ 106 Presentation Theaters. . ......................................................................... 155 Lunchtime Activities Hot Topics......................................................................................... 107 Learn the Technique........................................................................... 109 Afternoon Spotlight Sessions Aortic Endografts and Aneurysm Repair.. ............................................. 111 Integrating IVUS and FFR to Improve PCI Outcomes............................ 112. Next Generation Transcatheter Mitral Valve Therapies. . ......................... 112 Optimizing Use of Today’s Antithrombotic and Antiplatelet Drugs in ACS, PCI, and Atrial Fibrillation............................ 113 Surgical, Interventional, and Hybrid Procedures (Part 2): Valvular and Structural Heart Disease.................................................. 114 Special Twilight Sessions T r a n s c at h e t e r Cardiovascular Therapeutics Next Generation Optical Intravascular Imaging: OCT and NIR Spectroscopy................................................................ 133 Optimizing Primary PCI for STEMI (Part 2): Drugs, Devices, and Techniques.. ........................................................ 133 Special Twilight Sessions Partnership Session: Brazilian Society of Interventional Cardiology (SBHCI) and Gi2: Transcatheter Aortic Valve Replacement and Complex Coronary Intervention.............. 134 Partnership Session: p-c-i Live in Partnership with TCT: Practical Aspects of Coronary, Valvular, and Electrophysiologic Interventions.......................................................... 134 Practicalities and Pitfalls of Platelet Function Testing............................ 135 TCT Mediterranean. . ........................................................................... 135 Evening Programs. . ............................................................................... 161 Friday Breakfast Meetings............................................................................... 162 Clinical Cardiovascular Genetics and the Era of Personalized Medicine.. ....................................................... 114 Main Arena. . .......................................................................................... 138 Featured Clinical Research III. Drug-Eluting Stents, Drug-Coated Balloons, and PCI Pharmacology.................................... 115 How to Treat Theater: Endovascular and Structural Heart Disease...... 139 How to Treat Theater: Coronary Artery Disease.................................... 139 Challenging Case Multiplex Partnership Session: JIM at TCT......................................................... 115 Focus on India: Interactive Case Review and Panel Discussion............. 115 Challenging Case Theater................................................................... 140 Korean Interventional Cardiology Summit. . ........................................... 115 International Society-Sponsored Case Theater..................................... 140 Special Circulation Journal Session: The Most Important Interventional Papers from the Last Year. . .............. 116 Evening Programs. . ............................................................................... 156 Thursday Breakfast Meetings............................................................................... 157 Morning Spotlight Sessions Controversies in Interventional Cardiology: The Skeptic’s Corner.......................................................................... 140 Difficult Patients in Interventional Cardiology: The Art of Clinical Decision-Making..................................................... 141 TAVR Site Readiness: Organizing and Training Your Site to Prepare for TAVR..................................................................... 142 Main Arena. . .......................................................................................... 120 How to Treat Theater: Coronary Artery Disease.................................... 121 How to Treat Theater: Endovascular and Structural Heart Disease...... 122 Challenging Case Multiplex Challenging Case Theater................................................................... 123 International Society-Sponsored Case Theater..................................... 123 Maintenance of Certification (MOC) Course.. ........................................ 124 Special Sessions FDA Town Hall Meeting. . ..................................................................... 125 Morning Spotlight Sessions From Clinical Trials Evidence to Clinical Practice: Unraveling the Issues.. ........................................................................ 126 Next Generation Transcatheter Aortic Valve Therapies.......................... 126 Optimizing Primary PCI for STEMI (Part 1): The Systems Approach....... 127 Tough Calls in the Cath Lab: Are You Up to the Challenge?.................. 127 Presentation Theaters. . ......................................................................... 160 Lunchtime Sessions Hot Topics......................................................................................... 128 Learn the Technique........................................................................... 129 Afternoon Spotlight Sessions Deep Dive: Interventional Hypertension. . .............................................. 131 Drug-Coated Balloons: Clinical Data and Applications.......................... 132 Satellite Symposia Monday Evening Programs.............................................................................. 146 Tuesday Breakfast Meetings. . ........................................................................... 147 Presentation Theater South. . ............................................................... 150 Evening Programs.............................................................................. 150 Wednesday Breakfast Meetings. . ........................................................................... 152 Presentation Theater North................................................................. 155 Presentation Theater South. . ............................................................... 156 Evening Programs.............................................................................. 156 Thursday Breakfast Meetings. . ........................................................................... 157 Presentation Theater North................................................................. 160 Presentation Theater South. . ............................................................... 161 Evening Programs.............................................................................. 161 Friday Breakfast Meetings. . ........................................................................... 162 Poster Abstracts Map........................................................................... 166 Moscone Center Map.. .......................................................................... 168 www . t c t c o n f e r e n c e . c o m 3 TCT for Surgeons, Nurses/ Technologists, and Fellows TCT for Surgeons: Creating and Securing the Future 20th Annual Cardiovascular Nurse and Technologist Symposium Monday Monday The Valvular Heart Disease Summit (Part 1): Aortic Valve Therapies.......................................................................... 52 20th Annual Cardiovascular Nurse and Technologist Symposium...................................................................... 42 Tuesday Surgical, Interventional, and Hybrid Procedures (Part 1): Coronary Revascularization................................................................... 59 Tuesday Breakout Symposium I. The Great Debates. . .......................................... 58 The Valvular Heart Disease Summit (Part 2): Mitral Valve Therapies........................................................................... 93 Breakout Symposium II. Working in Today’s Cath Lab. . ........................... 59 Breakout Symposium III. Business Development and Operations.. ........... 59 Wednesday Innovative Surgical Techniques and Technologies................................. 106 Aortic Endografts and Aneurysm Repair.. ............................................. 111 Surgical, Interventional, and Hybrid Procedures (Part 2): Valvular and Structural Heart Disease.................................................. 114 RCIS Review Course............................................................................ 43 Special TCT Sessions for Cardiology Fellows Monday Board Review Course with Self-Assessment in Interventional Cardiology (Part 1)........................................................... 42 Tuesday Board Review Course with Self-Assessment in Interventional Cardiology (Part 2)........................................................... 58 Wednesday MOC Course Interventional Cardiology 2011 Update Module Review, 8:05 am .......................................................... 104 MOC Course Interventional Cardiology 2010 Update Module Review, 10:15 am ........................................................ 104 MOC Course Interventional Cardiology 2009 Update Module Review, 12:00 pm ........................................................ 104 ACC Fellows Session I. Advanced Training in Valvular Heart Disease........................................................................ 107 Thursday MOC Course Interventional Cardiology 2011 Update Module Review, 8:05 am .......................................................... 125 MOC Course Interventional Cardiology 2010 Update Module Review, 10:15 am ........................................................ 125 MOC Course Interventional Cardiology 2009 Update Module Review, 12:00 pm ........................................................ 125 ACC Fellows Session II. Advanced Training in Structural (Non-valve) Heart Disease................................................... 128 4 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience 5 Reasons to Attend 1 Late Breaking Clinical Science TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Late Breaking Trials A cornerstone of every TCT, late breaking trials are presented in the Main Arena and are typically the initial worldwide presentation of clinical trials, impactful single-center or multicenter registries, or important follow-up data from major randomized trials and first-in-man experiences with novel devices or drugs. Special Twilight Sessions A major highlight from last year’s TCT, the Special Twilight Sessions are can’t-miss evening sessions that highlight featured clinical research and presentations on the hottest topics in a more casual setting with hors d’oeuvres. Dedicated Oral, Poster, and Challenging Cases Video Abstract Presentations TCT 2011 will feature a four-and-a-half hour block dedicated to oral and poster abstract presentations and, new this year, challenging cases video abstracts. This will provide the opportunity to interact with peers in an intimate setting for critical review of science. 2 Practical Knowledge “How to Treat” Live Case Theaters For practitioners desiring a state-of-the-art review of contemporary interventional practice, TCT’s “How to Treat” Live Case Theaters are there to provide step-by-step approaches to basic and advanced interventions, covering a broad knowledge base as well as numerous new techniques and tips and tricks to improve care for patients with cardiovascular disease. Challenging Case Multiplex Theater Over 400 physicians submit their most challenging cases to be presented at TCT, with the most remarkable cases to be presented in the Challenging Case Multiplex Theater and published in Catheterization and Cardiovascular Interventions. 3 Networking With Colleagues 4 Focused Educational Activities TCTMD Connect TCTMD Connect is an online professional media network designed and developed just for you—the interventional cardiovascular professional. Along with your free membership to TCTMD (www.tctmd.com), you can now network with colleagues, blog about issues and updates relevant to you and your practice, and collaborate by uploading and downloading images, presentations, and cases. 14th Annual Self-Assessment Course for Interventional Cardiology This interactive course will include didactic and case presentations, image interpretation, and multiple choice (single best answer) questions to prepare you for your exam or enhance your overall understanding of interventional cardiology. 20th Annual Cardiovascular Nurse and Technologist Symposium The Annual Nurse and Technologist Symposium provides a forum for discussion of the latest advances in interventional, pharmacologic, structural heart, and endovascular strategies for the management of the cardiovascular patient. TCT for Surgeons: Creating and Securing the Future TCT for Surgeons is an in-depth course focusing on novel and advanced surgical techniques for surgeons interested in the most contemporary surgical techniques and catheter-based approaches. 5 Interactive Meeting Technology CRF Meetings Mobile App Keeping up to date with news and the best sessions at TCT has never been easier with our free app for the iPhone and iPad: Up-to-the-minute information on TCT, with extensive program, exhibitor, and faculty search tools, add integration with your mobile calendar. The free TCT mobile app is available from iTunes using the keyword “TCT”. A mobile Web site is available for those not using Apple products. Smart Tags With only your mobile device, access detailed information on the go, which include slides from late breaking trials and other presentations, exhibitor details and locations, and useful tips on San Francisco and the Moscone Center. Download the free app at http://gettag.mobi from your mobile device. www . t c t c o n f e r e n c e . c o m 5 Directors and Organizers Directors Scientific Committee Martin B. Leon, MD David H. Adams, MD Gregg W. Stone, MD Dominick J. Angiolillo, MD, PhD Josef Bartunek, MD, PhD Eric R. Bates, MD Co-Directors Olivier F. Bertrand, MD, PhD George D. Dangas, MD, PhD Deepak L. Bhatt, MD, MPH William A. Gray, MD William E. Boden, MD Roxana Mehran, MD Steven F. Bolling, MD Gary S. Mintz, MD Russell A. Brandwein, RPA-C Ralph G. Brindis, MD, MPH Associate Directors Todd J. Brinton, MD Bruce R. Brodie, MD Alexandre Abizaid, MD, PhD Daniel Burkhoff, MD, PhD Gary M. Ansel, MD Jacques Busquet, MD Robert O. Bonow, MD Josep Rodés-Cabau, MD Antonio Colombo, MD Christopher P. Cannon, MD Ted Feldman, MD Louis A. Cannon, MD Run-Lin Gao, MD John D. Carroll, MD Bernard J. Gersh, MB, ChB, DPhil David A. Cox, MD Anthony H. Gershlick, MD Michael E. Crawford, MD Juan F. Granada, MD Frank J. Criado, MD Liliana R. Grinfeld, MD Mark A. de Belder, MD, MA Eberhard Grube, MD Bernard de Bruyne, MD, PhD Ziyad M. Hijazi, MD, MPH Elazer R. Edelman, MD, PhD David R. Holmes Jr, MD David P. Faxon, MD Alice K. Jacobs, MD William F. Fearon, MD Michael R. Jaff, DO Francisco Fernandez-Aviles, MD, PhD Barry T. Katzen, MD Peter J. Fitzgerald, MD, PhD Dean J. Kereiakes, MD William J. French, MD Ajay J. Kirtane, MD, SM James A. Goldstein, MD Alexandra J. Lansky, MD Christopher B. Granger, MD Michael J. Mack, MD J. Aaron Grantham, MD Akiko Maehara, MD Giulio Guagliumi, MD Ian T. Meredith, MBBS, PhD Michael Guiry, RPA-C David J. Moliterno, MD Paul A. Gurbel, MD Jeffrey W. Moses, MD Christian W. Hamm, MD Masahiko Ochiai, MD, PhD Martial Hamon, MD John A. Ormiston, MB, ChB Kishore J. Harjai, MD Seung-Jung Park, MD, PhD Marian C. Hawkey, RN LeRoy E. Rabbani, MD Ziyad M. Hijazi, MD, MPH Mark Reisman, MD David J. Hildick-Smith, MD Patrick W. Serruys, MD, PhD W. Craig Hooper, PhD Sigmund Silber, MD Nancy Houston Miller, BSN, RN Varinder P. Singh, MD Yong Huo, MD Robert J. Sommer, MD Yang-Soo Jang, MD, PhD Paul S. Teirstein, MD Peter Juni, MD Renu Virmani, MD Aaron V. Kaplan, MD John G. Webb, MD Saibel Kar, MD Giora Weisz, MD John W. Karanian, PhD Harvey D. White, MD Sanjay Kaul, MD Mathew Williams, MD Morton J. Kern, MD Stephan Windecker, MD 6 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Ran Kornowski, MD Hans Krankenberg, MD Mitchell W. Krucoff, MD Massoud A. Leesar, MD Thierry Lefevre, MD JoAnn Lindenfeld, MD James B. McClurken, MD John A. McPherson, MD Marie-Claude Morice, MD Hilary Nierenberg, NP, MPH E. Magnus Ohman, MD Semih Oktay, PhD Jeffrey W. Olin, DO Manish A. Parikh, MD Helen Parise, ScD Amit Patel, MD, MS Ileana L. Pina, MD Stuart J. Pocock, PhD Jeffrey J. Popma, MD Matthew J. Price, MD Sunil V. Rao, MD Vivek Y. Reddy, MD Evelyn S. Regar, MD, PhD Bernhard Reimers, MD Mark Reisman, MD Charanjit S. Rihal, MD Ivan C. Rokos, MD Dierk Scheinert, MD Allan Schwartz, MD Warren Sherman, MD Georgios Sianos, MD, PhD Horst Sievert, MD, PhD Martina Kelly Speight, RN, BSN H. Robert Superko, MD David Taggart, MD, PhD Guillermo Tearney, MD, PhD Holger Thiele, MD Martyn R. Thomas, MD Craig A. Thompson, MD, MMSc Leif Thuesen, MD Jonathan M. Tobis, MD Zoltan G. Turi, MD E. Murat Tuzcu, MD Alec Vahanian, MD Marco Valgimigli, MD Ron Waksman, MD Gerald S. Werner, MD, PhD Janet F. Wyman, MSN, ACNS-BC Paul Yock, MD Christopher K. Zarins, MD Thomas Zeller, MD Bram D. Zuckerman, MD Organizational Committee Andrea Abizaid, MD, PhD Fernando Alfonso, MD, PhD Somjot S. Brar, MD Stephen Balter, PhD Antonio L. Bartorelli, MD Lee N. Benson, MD Joseph Carrozza, MD Christina A. Chadwick, RN, MSN Michael B. Collins, MD Joseph S. Coselli, MD Nick Curzen, PhD John S. Douglas Jr, MD Michael E. Farkouh, MD, MSc Frederick Feit, MD Philippe Genereux, MD Ulrich Gerckens, MD A. Marc Gillinov, MD Cindy L. Grines, MD Howard C. Herrmann, MD James B. Hermiller Jr, MD Richard R. Heuser, MD John McB. Hodgson, MD Leo Nelson Hopkins, MD Kurt Huber, MD Alice K. Jacobs, MD David E. Kandzari, MD Osamu Katoh, MD Susheel Kodali, MD Raghu Kolluri, MD Bon-Kwon Koo, MD, PhD Edward M. Kreps, MD Frederick Kushner, MD Glenn N. Levine, MD Scott Lim, MD Brij Maini, MD Tift Mann, MD D. Christopher Metzger, MD Philip M. Meyers, MD Issam D. Moussa, MD Srihari S. Naidu, MD Manesh R. Patel, MD Mahmood K. Razavi, MD John F. Rhodes, MD Binoy K. Singh, MD Thomas D. Stuckey, MD Clemens von Birgelen, MD, PhD Bonnie H. Weiner, MD, MSEC, MBA David O. Williams, MD Bernhard Witzenbichler, MD The World’s Premier Interventional Experience TCT2011 Associations and Affiliations American Association for Thoracic Surgery American College of Cardiology ASEAN Federation of Cardiology Association on Cardiovascular Interventions of the Polish Cardiac Society Belgian Working Group of Interventional Cardiology Brazilian Society of Interventional Cardiology British Cardiovascular Intervention Society Canadian Association of Interventional Cardiology Cardiac Society of Australia and New Zealand Cardiology Society of India CardioVascular Research Foundation Asia China Interventional Therapeutics Chinese Society of Cardiology Cardiovascular Intervention Association of Thailand Chinese Society of Cardiology Circulation: Cardiovascular Interventions TCT International Advisory Committee Argentina Rubén Piraino, MD Australia and New Zealand James Cameron, MD Belgium Glenn Van Langenhove, MD, PhD Brazil Alexandre Abizaid, MD Canada Erick Schampaert, MD Chile Oscar A. Mendiz, MD China Dayi Hu, MD Croatia Aleksander Ernst, MD, PhD Czech Republic Petr Kala, MD, PhD Denmark Anders Junker, MD Leif Thuesen, MD Colegio Argentino de Cardioangiologia Intervencionista Croatia Working Group of Iran Heart Association Singapore Cardiac Society Israeli Working Group on Interventional Society for Cardiovascular Cardiology/The Israel Heart Society Interventional Cardiology, Italian Society of Invasive Cardiology Croatian Cardiac Society Japanese Association of Czech Working Group of Interventional Cardiology of the Czech Society of Cardiology Danish Group of Interventional Cardiology Dutch Society of Interventional Cardiology Dutch Working Group on Interventional Cardiology Egyptian Society of Cardiology Finland Working Group on Interventional Cardiology Greece Working Group on Interventional Cardiology Heart Association of Thailand Under the Royal Patronage of His Majesty the King Hellenic Cardiological Society International Society of Endovascular Specialists Therapeutics Joint Interventional Meeting Journal of the American College of Cardiology Korean Society of Cardiology Malaysian Interventional Cardiology Society Cardiologia Intervencionista Society of Invasive Cardiovascular Professionals Spanish Working Group on Interventional Cardiology Spanish Society of Angiology and Vascular Surgery Stanford Biodesign Morocco Working Group on Swedish Working Group on Coronary Interventional Cardiology Nordic-Baltic Study Group of Interventional Cardiology Heart Disease Swedish Working Group on PCI/ Swedish Society of Cardiology p-c-i Live Swiss Society of Cardiology Pediatric Interventional Cardiac TCT Mediterranean Symposium Preventive Cardiovascular Nurses Association Russian Society of Endovascular Surgery Endovascular Therapy Cardiology and Angiology and New Zealand Sociedad Latin Americana de Mexican Society of Cardiology Russian Society of Interventional Cardiac Society of Australia Angiography and Interventions Sociedad de Cardiologia Intervencionista de Mexico Cardiovascular Intervention and International Symposium on Interventional Council of the T r a n s c at h e t e r Cardiovascular Therapeutics TCT Russia Turkish Working Group of Interventional Cardiology Working Group on Interventional Cardiology and Acute Coronary Syndrome/The Swiss Society of Cardiology Saudi Arabia Cardiology Interventional Group Science Innovation Synergy Egypt Latin America Spain Mohamed Sobhy, MD Oscar A. Mendiz, MD Marc Cairols, MD Europe Malaysia Josefina Mauri, MD Carlo Di Mario, MD Rosli Mod Ali, MD Sweden Finland Mexico Göran Olivecrona, MD Karl Andersen, MD, PhD Jose Luis Leyva Pons, MD Frederik Schersten, MD Greece Carlos Martínez-Sánchez, MD Switzerland Lambros Michalis, MD Morocco Giovanni Battista Pedrazzini, MD Georgios Parcharidis, MD Abdelhamid Moustaghfir, MD Thailand Iceland Poland Sarana Boonbaichaiyapruck, MD Karl Andersen, MD, PhD Waldemar Banasiak, MD Yingnoi Uboldejpracharak, MD India Russia Turkey Samuel K. Mathew, MD Bagrat G. Alekyan, MD Muzaffer Degertekin, MD, PhD Iran Zaza Kavteladze, MD United Kingdom Feridoun Noohi, MD Saudi Arabia Mark A. de Belder, MD Israel Mohammed Balghith, MD Ran Kornowski, MD Serbia Italy Miodrag Ostojic, MD Antonio Colombo, MD Singapore Giulio Guagliumi, MD Bernard Kwok, MD Japan South Korea Takeshi Kimura, MD Chong Yun Rhim, MD Masahiko Ochiai, MD www . t c t c o n f e r e n c e . c o m 7 Acknowledgments The TCT program development and organization Laura A. McKeown is a year-round effort. Many people play important Editorial Services Medical Writer/Editor roles that ensure the success of TCT by contributing Thomas Mortimer their experience and expertise. The Cardiovascular Editorial Services Proofreader Research Foundation wishes to give special thanks Cody Pietras to all those who have worked tirelessly and with Web Sites great dedication to our mission. Consultant Leonard Posso Graphic Designer Marketing and Creative Services Planning Group Johnnie White, CMP Elizabeth Burke Executive Director Executive Assistant Meetings and Educational Services Meetings and Educational Services Stephen Cannarelli Caitlin C. Cox Senior Design Manager Senior Medical Writer/Editor Marketing and Creative Services Editorial Services Jeff Chamlee Elizabeth Coyle Service Coordinator Multimedia Manager Senior Meeting Planner Web Sites Marketing and Creative Services Meeting Planning Irma Damhuis William A. Himmelsbach, MPH, FACHE President and Chief Executive Officer Matthew P. Pazaryna Chief Financial Officer Donald L. Abrams, Esq General Counsel Johnnie White, CMP Executive Director Meetings and Educational Services Industry Relations Administrative Support Staff Abby Rees Nancy Collins Program Coordinator Gabriella Gallo-Cisak CME Program Development Diane Salerno-Madrid Program Project Manager Adam Saunders E-Marketing and Customer Clinical Trials Center Rasha Aaskar Maria Alfonso Greg Simsic Sinan Biro Kim Dalton Consultant Sonia Burgher Director Medical Writer/Editor Marketing and Creative Services Isabel Corral External Relations Editorial Services Denise Tong Ecaterina Cristea Josh Hartman Alexander Damhuis Associate Director CME Coordinator CME Program Development Web Sites CME Program Development Lisa Hathaway Stella, CMP Christina DiFrancesco Senior Copy Editor Director Senior Coordinator, Grants Editorial Services Industry Relations Industry Relations Jason Kahn Scott Allan Wallick Rosa De Jesus Ossen Delbrun Marina Dizik Champika Djurkovic Ovidiu Dressler LaTosha Eligon Todd Worms Monica Embacher Tara Donegan Project Manager Martin Fahy Manager, Academic Content Meeting Planner Marketing and Creative Services Raza Hijazi Editorial Services Meeting Planning Margaret Zetts Cecilia Jade Hart Fun Lee, CMP Michelle Gan Program Coordinator Director Senior CME Coordinator CME Program Development Meeting Planning CME Program Development Ted Silverstein Stephanie Gutch Director Manager, Operations and Content Marketing and Creative Services Web Sites Todd Wagner Katie Herrion Katharine Lymberis Manager, Print Production Senior Associate Catalin Mindrescu Marketing and Creative Services Industry Relations Gary S. Mintz, MD Colleen Whelan Guadalupe Hogarty, CMP Gopinathan Mohan Director Senior Meeting Planner Sophia Papamitrou CME Program Development Meeting Planning Helen Parise, ScD Michael Houk Multimedia Designer Marketing and Creative Services Yael L. Maxwell Medical Writer/Editor Editorial Services 8 Tricia Rawh Management Team Senior Management Group program · Irene Hueter Jaclyn Jacobson Elena Konovalova Laura LaSalle Wangyue Liu Sarah Luijpers, PMP Mitchel Lustre Nicoleta Pavlovici Khary Perry Ecaterina Prepelita Eugene Salgado Raquel Sanchez Shawnalee Vassell Stepahnie Wolin Sarah McDaniel Douey Wright Program Planner Ke Xu CME Program Development Yuliya Yureneva T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 Finance Yuliya Bogomolny Jenni Kong Eileen Morales Cheryl Turnbull Human Resources Kelli O’Toole Emilia K. Valtcheva Office Services Aryel Flores De Valgaz The Jack H. Skirball Center for Cardiovascular Research Juan Carbonell Francy Castro Carlos Fernandez Ceballos Yan-Ping Cheng Gerard B. Conditt Duane Dennis Jennifer Duffy Juan F. Granada, MD Anguo Gu Jaime Guzman Greg L. Kaluza, MD, PhD Information Technology Jennifer McGregor Patricia Mount Louis Cruz Athanasios Peppas Richard Han Armando Tellez, MD Alain Moise Kathy Troyan Anthony Napoli Alyssa Wagner Kimberly White External Relations Irma Damhuis Judy Romero Geng-Hua Yi T r a n s c at h e t e r Cardiovascular Therapeutics Factoid Faculty Elissa Altin, MD Usman Baber, MD Louise Buchanan, MD Adriano Caixeta, MD, PhD Bimmer E. Claessen, MD, PhD Jose Costa, MD Daniel Silva Chamié de Queiroz, MD Isaac George, MD Philip Green, MD Diaa Hakim, MD Vishal Kapur, MD Farhan Khawaja, MD Thosaphol Limpijankit, MD Jorge Magallon, MD Vinod Patel, MD Elias Sanidas, MD Georgios Vlachojannis, MD Tadayuki Yakushiji, MD Jennifer Yu, MD Board of Directors of the Cardiovascular Research Foundation Eric B. Woldenberg, Esq Office of Legal Affairs Donald L. Abrams, Esq Quality Assurance Chairman William A. Himmelsbach, MPH, FACHE President and Chief Executive Officer Joseph G. Beck Whitney Petrie Colette Y. Gardner Maria Rossolino Jeffrey W. Moses, MD Arthur J. Pergament Eric A. Rose, MD Marvin L. Woodall www . t c t c o n f e r e n c e . c o m 9 Acknowledgments Columbia University Medical Center AnnMarie Kelly Delita Glori-Feri, RN Rose Ang, RN Eileen Madison Denise Groff, RN Samantha Allen Faculty Enid Montalvo Dennis Sta. Maria, RN Scott Cooper, RN Dora Mussenden Derrrick Horne, RN Serge Sabo Sr. Diane Pearson Ellen Moreno, RN Sheehan Raab Jackie Price-Saunders Ellen Pitiger, RN Sheri Pinto, RN Brenda Puentes Emil Osorno, RN Siobhan Reilly, RN Aura Adelhaydy Ramirez Eufemia Penaflor, RN Soojin Horland, RN Fernando Ramirez Evaine Iral-Fallurin, RN Stephanie Quach Luc, RN Catherine Reyes Fall Fatou-Khady Stephen Balter, PhD Jacqueline Rosenthal Felicia Leon Tamara Grazette, RN Evelyn Rendon Gerard Cowles, RN Tamara Van Gelder Tiesha Ruiz Gleonisi Ramirez Tina Jones Toni Russo Greta Martin Viola King Diane Salerno-Madrid Harold Stella Vivian Tamara Jeanie Sohn Hilda Devlin, RN Woodley Perpignan, RN Alina Sokolinskaya Holly McCall, RN Yang Fang Annicia Thomas Hongge Wei Yovana Chardon Samantha Tsiolis Isidro Gonzalez Yvette Reyes Jaime Crist, RN Zaira Marcelino Jan Greenfield, RN Zoraya Boissard Mark A. Apfelbaum, MD Michael B. Collins, MD Braulio Flores, MD Philippe Genereux, MD Alexander Gorodnitskiy, MD William A. Gray, MD Rebecca Hahn, MD Nellie Kalcheva, MD Ajay Kirtane, MD Susheel Kodali, MD Edward Kreps, MD Martin B. Leon, MD Jeffrey W. Moses, MD Manish Parikh, MD LeRoy E. Rabbani, MD Norbert Rainford, MD Abdollah Sedighi, MD Clinical Research Staff Warren Sherman, MD Angelica Castaneda, BS Binoy Singh, MD Diane Weber Cannone, BA Varinder Singh, MD Vasiliki Chantziara, MD Robert J. Sommer, MD Kate Dalton, MS Gregg Stone, MD Zumara de la Cruz, BS Giora Weisz, MD Eunice Dilone Mathew Williams, MD Ahmed Hassanein, MD Ashlee Mattone, BS Clinical Instructors Andy Morales, MD Benoit Daneault, MD Gordian Ndubizu, BS Isaac George, MD Lauren Privitera, MPH Elana Y. Koss, MD Jean-Michel Paradis, MD Fernando Sosa, BS Philip Green, MD Niurka Suero, BA, MA Vishal Kapur, MD Joyce Ann Thomas, BS Farhan Khawaja, MD Giora Weisz, MD Jorge Magallon, MD Treena Williams, ME Tamim Nazif, MD Prabhdeep Sandhu, MD Wilson Arango, FNP- BC Russell Brandwein, PA-C Marian Hawkey, RN Hilary Nierenberg, NP, MPH 10 Rachel Yoo, MA Cath Lab Clinical Staff Tiffany Wongh, PA-C Elaine Rodriguez, MPH Sowmya Shree, MD Fellows Susan Schnell, ACNP-c Yasir Qureshi, MD Alex Castillo Alla Ogii-Landis, RN Andrew Stefanski Annelle Williams Araceli Limbaga, RN Barbara Stock, RN Beatriz Custodio Administrative Staff Betty Yu-Chong, RN Regina Amelko Brian Aquino, RN C. Jeanette Bermeo Brian Padilla Donna Brown Byron Johnson Rosie Calcano Christine Carthy, RN Beth Carraturo Christopher Bechtel Veronica Garcia Claudia Echeverry Tiffany Gibney Danielle Thompson Charlette Gomez David Borsh, RN Yemilet Gonzalez Debbie Donaldson Stacy Hall Debbie Maccaro Bevi James Deborah Plant, RN Suzanne Jakubiak Deirdre Conlon, RN Rona Kahn Del Mundo, Regel, RN program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Janice Sbarro Jhan Nunez Joanna Castro Jodi Conway, RN Joel De Jesus Kathleen Casey, RN Kelle Brocker, RN Kelly Light, RN Ketevan Telia Lenny Guzman Leslyn Hall Lihua Fang Louis Lopez Lu Kan Gorman RN Margaret Griffin, RN Maria Lourdes Tan-Uy,RN Maria Mamuri, RN Maria Younessian, RN Maria-Cristina Beltran, RN Maricar Jordana, RN Mary Egan, RN Melanie Diaz, RN Melissa Pusterla, RN Michael De Leon, RN Michael Sgarella Michele Foley, RN Michelle Lindquist, RN Michelle Murray, RN Miriam Candaroma, RN Moira Smith RN Myriam Medrano Nenita Generales, RN Noel Castor, RN Norma Ennis Osama Amine Patrick Hayford Patrick Kline, RN Paul Kelley, RN Phyllis Rodriguez Rene Ambrona Rodello Diamante Ronald Rigor, RN Physician Assistants Alicia Adams, RPA-C Sean Ahearn, RPA-C Anna Akker, RPA-C Gretchen Andersen, RPA-C Michael Bergman, RPA-C Priscilla Binsack, RPA-C Russell Brandwein, RPA-C Mario Buss, RPA-C Kamman Chan, RPA-C Tara Collins, RPA-C Pilar Dolcimascolo, RPA-C Galina Dumchin, RPA-C Marian Elbert, RPA-C Jessica Forman, RPA-C Neisha Hariprashad, RPA-C Seing Houy, RPA-C Nancy Copeland-Kelley, RPA-C Kristin Maidhof, RPA-C Irina Pilosova, RPA-C Michael Querijero, RPA-C Eileen Redmond, RPA-C Sofia Romero, RPA-C Jamie Shein, RPA-C Mindy Sporn, RPA-C Bethany West, RPA-C Kayin Wu, RPA-C The World’s Premier Interventional Experience TCT2011 Abstract Reviewers The TCT Course Directors and the Abstract Selection Committee, which was chaired by Gary S. Mintz, MD, wish to express their sincere appreciation to all the physicians who selflessly donated their time and expertise as TCT Abstract Reviewers. J. Dawn Abbott, MD Andrea Abizaid, MD Takashi Akasaka, MD Fernando Alfonso, MD Steven Almany, MD John Ambrose, MD Zahid Amin, MD Dominick Angiolillo, MD Gary M. Ansel, MD David Antoniucci, MD Robert Applegate, MD Stephen Balter, MD Adrian Banning, MD Gerald Barbeau, MD Colin Barker, MD Jozef Bartunek, MD Theodore A. Bass, MD Eric R. Bates, MD Mark Bates, MD Kevin Beatt, MD Jorge Belardi, MD Keith Benzuly, MD Nirat Beohar, MD Daniel Berman, MD Daniel Berrocal, MD Olivier Bertrand, MD Anuj Bhasin, MD Deepak Bhatt, MD John Bittl, MD William Boden, MD Steven Bolling, MD Raoul Bonan, MD J.J.R.M. (Hans) Bonnier, MD Alessandro S. Bortone, MD Bruce Bowers, MD Somjot Brar, MD Jeffrey Breall, MD Stephen Brecker, MD Sorin Brener, MD Carlo Briguori, MD Emmanouil Brilakis, MD Ralph Brindis, MD Jeffrey Brinker, MD Bruce R. Brodie, MD Maurice Buchbinder, MD Robert Byrne, MD Christopher P. Cannon, MD Louis A. Cannon, MD Davide Capodanno, MD Blase Carabello, MD Mauro Carlino, MD John Carroll, MD Joseph P. Carrozza, MD Paul N. Casale, MD Charles E. Chambers, MD Seemant Chaturvedi, MD Shaoliang Chen, MD Stanley Chetcuti, MD Alaide Chieffo, MD Kenneth Chin, MD Leslie Cho, MD Michael W. Cleman, MD Marc Cohen, MD David Cohen, MD Mauricio Cohen, MD Tyrone Collins, MD Antonio Colombo, MD Jose A. Condado, MD Jose De Ribamar Costa, MD David Cox, MD Michael Crawford, MD Fernando Cura, MD Nick Curzen, MD Donald Cutlip, MD Charles J. Davidson, MD Jose M. De La Torre Hernandez, MD Robbert De Winter, MD Larry S. Dean, MD Gregory Dehmer, MD Ali Denktas, MD Germano Di Sciascio, MD Nabil Dib, MD Stefanie Dimmeler, MD Daniel Diver, MD Simon R. Dixon, MD Douglas Drachman, MD Henricus J. Duckers, MD Vladimir Dzavik, MD Holger Eggebrecht, MD Stephen G. Ellis, MD Raimund Erbel, MD Andrejs Erglis, MD David Erlinge, MD Steven M. Ettinger, MD Peter Fail, MD Tony Farah, MD Michael Farkouh, MD Dave Faxon, MD William F. Fearon, MD Frederick Feit, MD Ted Feldman, MD Dmitriy Feldman, MD Fausto Feres, MD Francisco Fernandez-Aviles, MD Michael Fifer, MD Hans R. Figulla, MD Tim A. Fischell, MD Gregory Fontana, MD Robert Freedman, MD William French, MD Shmuel Fuchs, MD Lawrence Garcia, MD Hector Garcia-Garcia, MD Eulogio Garcia, MD Kirk Garratt, MD Efrain Gaxiola, MD Junbo Ge, MD Jon George, MD Anthony Gershlick, MD Gary Gershony, MD Ian Gilchrist, MD Linda Gillam, MD Robert Giugliano, MD Dietmar Glogar, MD Sheldon Goldberg, MD Steven Goldberg, MD Mark Goldberger, MD Paul C. Gordon, MD Evelyne Goudreau, MD Neil Goyal, MD Juan F. Granada, MD Christopher Granger, MD William A. Gray, MD Liliana Grinfeld, MD Luis Gruberg, MD Marek Grygier, MD Giulio Guagliumi, MD Luis A. Guzman, MD Jaap N. Hamburger, MD Michalis Hamilos, MD Yaling Han, MD George Hanzel, MD Jan Harnek, MD Robert Harrington, MD Michael Haude, MD Jose Henriques, MD Michel Henry, MD Timothy D. Henry, MD David J. R. Hildick-Smith, MD Jonathan Hill, MD Willibald Hochholzer, MD Rainer Hoffmann, MD Ralf Holzer, MD Myeong-Ki Hong, MD Stephen Hoole, MD Craig Hooper, MD Eric Horlick, MD Phillip Horwitz, MD Dongming Hou, MD Thomas Ischinger, MD Alice K. Jacobs, MD Michael R. Jaff, MD Farouc Jaffer, MD Ik-Kyung Jang, MD Lisa Jennings, MD Allen Jeremias, MD Neeraj Jolly, MD Sanjit Jolly, MD Christoph Kaiser, MD Petr Kala, MD Greg L. Kaluza, MD Soo-Jin Kang, MD Hsien-Li Kao, MD Samir Kapadia, MD Aaron Kaplan, MD Adnan Kastrati, MD Barry Katzen, MD Upendra Kaul, MD Henning Kelbaek, MD Dean Kereiakes, MD R. Stefan Kiesz, MD Young-Hak Kim, MD Hyo-Soo Kim, MD Nicholas Kipshidze, MD Ajay J. Kirtane, MD Neal Kleiman, MD Lloyd Klein, MD Raghu Kolluri, MD David Kong, MD Jacques Koolen, MD Ran Kornowski, MD Jan Kovac, MD Zvonimir Krajcer, MD Hans Krankenberg, MD Henry Krum, MD Aaron Kugelmass, MD Michael Kutcher, MD Vincent On-Hing Kwok, MD Jean-Marc Lablanche, MD Antoine Lafont, MD Roger Laham, MD Gervasio Lamas, MD T r a n s c at h e t e r Cardiovascular Therapeutics John Lasala, MD Azeem Latib, MD Bonello Laurent, MD Michel Le May, MD Guy LeClerc, MD Michael Lee, MD Massoud Leesar, MD Pedro Lemos, MD Jonathan Leor, MD Norman Lepor, MD Amir Lerman, MD Michael Lim, MD Thosaphol Limpijankit, MD Hugo Londero, MD Robert Lookstein, MD Chaim Lotan, MD Kapildeo Lotun, MD Tom Mabin, MD Lindsay Machan, MD Akiko Maehara, MD Francesco Maisano, MD Ganesh Manoharan, MD Steven Manoukian, MD Jack Martin, MD Pedro Martinez-Clark, MD John A. McPherson, MD Julinda Mehilli, MD Roxana Mehran, MD Maurizio Menichelli, MD D. Chris Metzger, MD Erich Minar, MD David J. Moliterno, MD Michael Mooney, MD Pedro Moreno, MD Marie-Claude Morice, MD J. Brent Muhlestein, MD Brad Munt, MD Toshiya Muramatsu, MD Subbarao Myla, MD Srihari Naidu, MD Massimo Napodano, MD Franz-Josef Neumann, MD Thach Nguyen, MD Stephen Nicholls, MD Andrzej Ochala, MD Masahiko Ochiai, MD Takao Ohki, MD Goran Olivecrona, MD William O’Neill, MD Charles D. O’Shaughnessy, MD Miodrag Ostojic, MD Igor Palacios, MD David Paniagua, MD Keyur Parikh, MD Seung-Jung Park, MD Raghotham Patlola, MD Wes Pedersen, MD Carlos Pedra, MD Marc Penn, MD John Petersen, MD Harry R. Phillips, MD Nicolo Piazza, MD Augusto Pichard, MD Nico Pijls, MD Duane Pinto, MD Michael Poon, MD Francesco Prati, MD Matthew J. Price, MD John Puskas, MD Shakeel Qureshi, MD Leroy Rabbani, MD www . t c t c o n f e r e n c e . c o m 11 Acknowledgments Sunil Rao, MD Sudhir Rathore, MD Simon Redwood, MD Jon Resar, MD Expedito Ribeiro, MD Charanjit Rihal, MD David Rizik, MD Josep Rodes-Cabau, MD Jason Rogers, MD Ivan Rokos, MD Eric Roselli, MD Jamil Saad, MD Robert D. Safian, MD Francesco Saia, MD Luigi Salemme, MD Giuseppe Sangiorgi, MD Teguh Santoso, MD Gennaro Sardella, MD Lowell Satler, MD Jorge Saucedo, MD Erick Schampaert, MD Bruno Scheller, MD Paul Schoenhagen, MD Joachim Schofer, MD Helmut Schuhlen, MD Gerhard Schuler, MD Allan Schwartz, MD Amit Segev, MD Hubert Seggewiss, MD Victor Serebruany, MD Ashok Seth, MD Samin Sharma, MD Marc Shelton, MD Warren Sherman, MD Mehdi Shishehbor, MD Dirk Sibbing, MD Robert Siegel, MD Horst Sievert, MD Ulrich Sigwart, MD Sigmund Silber, MD Frank Silvestry, MD Tomasz Siminiak, MD Daniel Simon, MD Richard Smalling, MD Mohamed Sobhy, MD Robert Sommer, MD Amanda Sousa, MD Vankeepuram Srinivas, MD Eugenio Stabile, MD Terje Steigen, MD Thomas D. Stuckey, MD Satoru Sumitsuji, MD Robert Superko, MD Maarten J. Suttorp, MD Corrado Tamburino, MD Huay-Cheem Tan, MD Jean-François Tanguay, MD Mitsuyasu Terashima, MD Martyn Thomas, MD Christopher Thompson, MD Leif Thuesen, MD Henry Ting, MD Jonathan M. Tobis, MD Carl L. Tommaso, MD Pim Tonino, MD Sam Tsimikas, MD Thomas Tu, MD E. Murat Tuzcu, MD Kinzo Ueda, MD Barry Uretsky, MD Marco Valgimigli, MD 12 program · Glenn Van Langenhove, MD Stefan Verheye, MD Francesco Versaci, MD Renu Virmani, MD Clemens Von Birgelen, MD Marco Wainstein, MD Ron Waksman, MD Darren Walters, MD Thomas Walther, MD Jie Wang, MD Sergio Waxman, MD Bonnie H. Weiner, MD Neil J. Weissman, MD Giora Weisz, MD Peter Wenaweser, MD Brian Whisenant, MD Robert Whitbourn, MD Christopher White, MD Harvey White, MD Michael Wholey, MD Robert L. Wilensky, MD Mathew Williams, MD David Williams, MD Peter Wilmshurst, MD B. Hadley Wilson, MD Stephan Windecker, MD Bernhard Witzenbichler, MD Jochen Wöhrle, MD Wojciech Wojakowski, MD S. Chiu Wong, MD Bo Xu, MD Alan Yeung, MD Hiroyoshi Yokoi, MD Andreas Zeiher, MD David Zhao, MD Late Breaking Trial and First Report Reviewers Steven Bailey, MD Michel Bertrand, MD David Cohen, MD Antonio Colombo, MD George D. Dangas, MD David Faxon, MD Ted Feldman, MD Bernard Gersh, MD Tony Gershlick, MD Juan F. Granada, MD Liliana Grinfeld, MD Christian Hamm, MD Adnan Kastrati, MD Sanjay Kaul, MD Dean Kereiakes, MD Ajay J. Kirtane, MD Martin B. Leon, MD Morice Marie-Claude, MD Roxana Mehran, MD Ian T. Meredith, MD Gary S. Mintz, MD David Moliterno, MD Jeffrey W. Moses, MD John Ormiston, MD Seung-Jung Park, MD Sigmund Silber, MD Gregg W. Stone, MD John G. Webb, MD T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Giora Weisz, MD Karl-Heinz Kuck, MD Harvey White, MD Massoud Leesar, MD Stephan Windecker, MD Pedro Lemos, MD Martin B. Leon, MD Challenging Case Reviewers Scott Lim, MD J. Dawn Abbott, MD Ganesh Manoharan, MD Alexandre Abizaid, MD Patrick Mccarthy, MD Andrea Abizaid, MD Roxana Mehran, MD S. Hinan Ahmed, MD Neil Moat, MD Dominick Angiolillo, MD Douglass Morrison, MD Antonio Bartorelli, MD Issam Moussa, MD Theodore Bass, MD John Ormiston, MD Eric Bates, MD Igor Palacios, MD Mark Bates, MD Seung-Jung Park, MD Jorge Belardi, MD Lynn Peng, MD Lee Benson, MD Anna Sonia Petronio, MD John Bittl, MD Nicolo Piazza, MD Peter Block, MD Duane Pinto, MD Raoul Bonan, MD Jeffrey Popma, MD Emmanouil Brilakis, MD John Reilly, MD Jeffrey Brinker, MD Chet Rihal, MD Maurice Buchbinder, MD Carlos Ruiz, MD Samuel Butman, MD Lowell Satler, MD Blase Carabello, MD Robert Schainfeld, MD Charles Chambers, MD Joachim Schofer, MD Alaide Chieffo, MD Gerhard Schuler, MD Robert Chilton, MD Robert Schwartz, MD Mehmet Cilingiroglu, MD Allan Schwartz, MD Mauricio Cohen, MD Ashok Seth, MD Tyrone Collins, MD Paul Sorajja, MD Antonio Colombo, MD Martyn Thomas, MD Marco Costa, MD Jonathan Tobis, MD Charles Davidson, MD Carl Tommaso, MD Larry Dean, MD Thomas Tsai, MD Douglas Drachman, MD Thomas Tu, MD David Faxon, MD E. Murat Tuzcu, MD Ted Feldman, MD Barry Uretsky, MD Marc Feldman, MD Nicolas Van Mieghem, MD Gregory Fontana, MD Bonnie Weiner, MD Olaf Franzen, MD Olaf Wendler, MD Ian Gilchrist, MD Brian Whisenant, MD Steven Goldberg, MD Thomas Zeller, MD James Goldstein, MD Paul Grayburn, MD Donald Hagler, MD Timothy Henry, MD James Hermiller, MD Richard Heuser, MD Ziyad Hijazi, MD John Hirshfeld, MD Alice Jacobs, MD Allen Jeremias, MD Thomas Jones, MD Samir Kapadia, MD Pieter Kappetein, MD Navin Kapur, MD Morton Kern, MD Carey Kimmelstiel, MD Takeshi Kimura, MD Ran Kornowski, MD Zvonimir Krajcer, MD Michael Mack, MD Francesco Maisano, MD The World’s Premier Interventional Experience TCT2011 Commercial Support T r a n s c at h e t e r Cardiovascular Therapeutics Commercial Support Acknowledgement TCT 2011 is sponsored by the Cardiovascular Research Foundation and partially funded through educational grants from commercial supporters. The Cardiovascular Research Foundation strives to ensure that its programs are as educational as possible and free from bias. To support this endeavor, TCT directors and co-directors create organizational and scientific committees to assist in educational content development and content oversight for live cases, spotlight sessions, case reviews, practical workshops, and scientific symposia. These sessions are developed without influence from commercial supporters. The educational grant support of our industry colleagues, who, like the Cardiovascular Research Foundation, are dedicated to educating medical professionals and the public to enhance patient outcomes, helps to make each TCT possible. The Cardiovascular Research Foundation gratefully acknowledges the TCT 2011 MAJOR BENEFACTORS: Abbott Vascular AstraZeneca Boston Scientific Corporation Cordis Cardiac and Vascular InstituteSM Edwards Lifesciences Medtronic CardioVascular The Cardiovascular Research Foundation appreciates the educational grant support for the Faculty Support Program provided by: ABIOMED, Inc. AngioScore, Inc. Biotronik Boston Scientific Corporation MAQUET Cardiovascular Medtronic CardioVascular The Cardiovascular Research Foundation gratefully acknowledges the TCT 2011 BENEFACTORS: ABIOMED, Inc. Terumo Medical Corporation TherOx, Inc. The Cardiovascular Research Foundation gratefully acknowledges the TCT for Surgeons: Creating and Securing the Future MAJOR BENEFACTORS: Abbott Vascular Edwards Lifesciences Medtronic CardioVascular The Cardiovascular Research Foundation appreciates the educational grant support for TCT 2011 provided by: BridgePoint Medical, Inc. Cook Medical Cytori Therapeutics Direct Flow Medical, Inc. Genzyme Guerbet LLC Lutonix Mitralign, Inc. Tryton Medical, Inc. Valtech Cardio W.L. Gore & Associates The Cardiovascular Research Foundation appreciates the educational grant support for TCT for Surgeons: Creating and Securing the Future provided by: Boston Scientific Corporation Cook Medical Direct Flow Medical St. Jude Medical The Cardiovascular Research Foundation appreciates the educational grant support for the 20th Annual Cardiovascular Nurse Technologist Symposium provided by: Abbott Vascular Boston Scientific Corporation Cordis Cardiac and Vascular InstituteSM Medtronic CardioVascular St. Jude Medical Disclosure Statement It is the policy of the Cardiovascular Research Foundation to ensure balance, independence, objectivity, and scientific rigor in all of its sponsored educational activities. Commercial support from industry does not influence educational content, faculty selection, and/or faculty presentations, and, therefore, does not compromise the scientific integrity of the educational activity. Discussion of off-label product usage and/or off-label product use during live cases is made at the sole discretion of the faculty. Off-label product discussion and usage are not endorsed by the Cardiovascular Research Foundation or the conference directors of this activity. Faculty participating in continuing medical education activities sponsored by the Cardiovascular Research Foundation are required to disclose to the activity audience any real or apparent conflicts of interest related to the content of their presentations. Faculty not complying with this policy are not permitted to participate in this activity. (As of 9/26/2011) www . t c t c o n f e r e n c e . c o m 13 Special Activities Education Challenging Case Multiplex and Poster Presentations Keynote Speaker: Michio Kaku, PhD The renowned theoretical physicist, futurist, and author Dr. Michio Kaku will be providing the keynote address, “The Future of Humankind,” Wednesday, November 9, 10:40 am, in the Main Arena of the Moscone Center. Please see page 100 for the complete listing. Please drop off your business card at the CRF booth in the Partnership Pavilion on the first floor of Moscone North for a chance to win autographed copies of Dr. Kaku’s latest book, Physics of the Future. There will be a book signing with Dr. Kaku in the Partnership Pavilion on Wednesday, November 9, at 11:30 am. Dedicated Poster and Oral Abstract and Challenging Cases Video Abstracts The presentation of original peer-reviewed research is the basis of scientific discovery, representing the heart of academic medicine and offering participants opportunities to interact with peers in an intimate setting for critical review prior to manuscript generation. To emphasize TCT’s belief in the importance of such research, all accepted abstracts will be presented in a dedicated four-and-a-halfhour block during which there will be few competing sessions. Abstracts, both oral and poster, will be downloadable during TCT in electronic format via TCTMD.com and from the e-abstract viewing stations located throughout the Moscone Center. All abstracts are published in a special supplement of the Journal of the American College of Cardiology. Please see pages 60 and 82 for complete listings. New this year, Challenging Cases Video Abstracts will be presented during the Poster Abstract Sessions. Please see page 79 for complete listings. Tuesday, November 8 Poster Abstract Sessions 8:00 am-10:00 am The Challenging Case Multiplex will include two theaters, the Challenging Case Theater and the International Society-Sponsored Case Theater. Over 550 physicians submitted their most challenging coronary and endovascular intervention and structural heart disease cases to be presented at TCT. The most remarkable cases will be presented in the Challenging Case Theater and published in Catheterization and Cardiovascular Interventions. New this year, Challenging Cases Video Abstracts will be presented during the poster session on Tuesday, 8:00 am-10:00 am. Challenging cases will also be shown in the multiplex organized under the auspices of numerous international societies in the International Society-Sponsored Case Theater. The Challenging Case Multiplex is located in Hall D of Moscone North. Please see pages 103, 123, and 140 for complete listings. program · Hosted during the evenings of TCT Week, Special Twilight Sessions will highlight featured clinical research, presentations on the hottest topics in interventional cardiology and hosted must-see international sessions in a more casual setting with hors d’oeuvres. Please see pages 54, 96, 114, and 134 for complete listings. Monday through Thursday, November 7-10 6:00 pm-8 :00 pm The Moscone Center Maintenance of Certification (MOC) Course and ABIM Simulation Sessions The MOC Course will prepare you with the 2009, 2010, and 2011 update modules and enhance your knowledge base and get you updated for your ten-year recertification on the ABIM and ABVM exams. These sessions will be planned and developed by the ACC in partnership with CRF. You can earn up to 30 credit points from the home study module sessions at the MOC Course and an additional 20 credit points for participating in the Practice Improvement Module (PIM). TCT can offer you up to 50 credit points, half of the 100 credit points needed to sit for the secure recertification examination. Please see pages 104 and 124 for complete listings. Tuesday, November 8 1:00 pm-6:00 pm Hands on Hearts ACC Educational Sessions Co-sponsored by the American College of Cardiology (ACC) and the Cardiovascular Research Foundation (CRF) Hot Topics in Clinical Cardiology: ACC.11 Highlights for the Intervention, Invasive, and General Cardiologist (page 89) Wednesday, November 9 12:15 pm-1:45 pm ACC Fellows Session I. Advanced Training in Valvular Heart Disease (page 107) Special JACC Session: How to Write and Evaluate Medical Journal Articles (page 109) Thursday, November 10 12:15 pm-1:45 pm ACC Fellows Session II. Advanced Training in Structural (Non-valve) Heart Disease (page 128) ACC Practitioners Session: Innovations to Manage, Maintain, and Expand Your Clinical Practice (page 128) Oral Abstract Sessions 10:15 am-12:30 pm 14 Special Twilight Sessions T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s A favorite of TCT attendees, Hands on Hearts includes actual pathological specimens demonstrating human heart disease as well as CT-generated casts of human hearts prior to intervention, ventricular septal disease, valves, cardiomyopathies, coronary anomalies, and special video vignettes from the bioskills sessions presented at CRF’s Transcatheter Valve Therapies (TVT) workshop. Please visit the Hands on Hearts Pavilion in Hall D of Moscone North. Wednesday and Thursday, November 9-10 9:00 am-5:00 pm Friday, November 11 9:00 am-12:00 pm Learn the Technique Lunchtime Sessions and Spotlight Sessions New in 2011, the Learn the Technique Lunchtime Sessions will demonstrate step-by-step approaches to advanced interventional techniques, relying heavily on patient cases to showcase tips and tricks The World’s Premier Interventional Experience TCT2011 to achieve success while avoiding (and, if necessary, managing) complications. Please see pages 109 and 129 for complete listings. Spotlight Sessions are a brand new approach to the concurrent sessions from previous TCTs and are now focused, clinical issue-centered sessions with featured lectures, case presentations, and special “summary” sessions. Please see pages 104, 111, 126, 131, and 140 for complete listings. TCT for surgeons: Creating and securing the future The integrated four-day course within TCT Week will be of special interest to cardiac and vascular surgeons, highlighting advanced techniques and emerging devices specific to cardiovascular surgery, as well as emphasizing emerging areas of percutaneous and minimally invasive therapies in which the surgeon is increasingly participating or leading, including transcatheter valve therapies and structural heart and aortic aneurysm repair. Please see pages 52, 59, 93, 106, 111, and 114 for complete listings. 20th Anniversary of the Cardiovascular Nurse Technologist Symposium Join us as we celebrate the 20th anniversary of the Cardiovascular Nurse and Technologist Symposium. The symposium began two decades ago, when TCT Director Martin B. Leon, MD, then at Washington Hospital Center (Washington, DC), invited nurses working there to share their expertise at TCT. Please see pages 42 and 58 for complete listings. Networking Opportunities Partnership Pavilion Come visit the CRF booth on the first floor of Moscone North to learn about the services CRF offers and also meet representatives from the American College of Cardiology and NewYork-Presbyterian/ Columbia University Medical Center. For more information about each of these organizations, please visit CRF at www.crf.org, the ACC at www.cardiosource.org/acc, NewYorkPresbyterian at www.nyp.org, and Columbia University Medical Center at www.cumc.columbia.edu. Exhibit Hall Opening and Reception Please join us at the opening of the Exhibit Hall in the Moscone Center for lunch at 12:00 pm on Tuesday, November 8. Also, there will be a special cocktail reception in the Exhibit Hall on Tuesday, November 8, 5:30 pm-6:30 pm. All are welcome! Attendee Lounge Sponsored by TCTMD Connect Meet with colleagues and connect with other professionals at the Attendee Lounge, in Hall D of Moscone North, sponsored by TCTMD Connect, an online professional media network designed and developed just for you—the interventional cardiovascular professional. Along with your free membership to TCTMD (www.tctmd.com), you can now network with colleagues, blog about issues and updates relevant to you and your practice, and collaborate by uploading and downloading images, presentations, and cases. To sign up for TCTMD Connect, please visit www.tctmd.com/connect, and please visit the Attendee Lounge sponsored by TCTMD Connect in Hall D of Moscone North. Art from the Heart Art from the Heart is a sculpture exhibition provided by the international awardwinning sculptor Akiva Huber. Be sure to see Mr. Huber’s exhibition during TCT outside Hall D in Moscone North. Technology Smart Tags at TCT Smart tags are made possible through support from Edwards Lifesciences With only your mobile device, access detailed information and the slides from the late breaking trial presentations and abstract posters. Smart tags will be located on the signs outside the room where late breaking trials are presented and in the poster abstract hall. Simply download the free app at http://gettag.mobi from your mobile device to gain access to the late breaking trial presentations, and download the QR code reader for your device to gain access to the abstract posters. T r a n s c at h e t e r Cardiovascular Therapeutics CRF MEEtings App for iPhone and iPad The CRF Meetings App is made possible through support from Cook Medical Keeping up to date with news and finding the best sessions at TCT has never been easier with our free app. You can get up-todate information on TCT, search agendas, exhibitors, and faculty, add sessions to your calendar, find out what’s going on in San Francisco, and view the Virtual TCT stream and the new “Best Practices” feature. You can also network with faculty and other TCT attendees. The free CRF Meetings App is available from iTunes with the keyword “CRF Meetings”. TCTMD Gold An initiative to provide an enhanced online educational experience to the interventional cardiovascular community, this TCTMD offering includes access to multimedia versions of presentations from TCT and other conferences, downloadable PowerPoint slides, and a host of premium educational content in addition to continuous access to news and other educational opportunities now available to current TCTMD members. Visit the TCTMD Gold booth during TCT to learn more about TCTMD Gold and to take a test drive, or visit www.tctmd.com/gold. Virtual TCT Virtual TCT delivers live and on-demand viewing of the Main Arena during TCT 2011 and for 30 days after the conference. Access to Virtual TCT is provided complimentary to all paid TCT Week and TCT in 3 attendees. Wednesday and Thursday, November 9-10 8:00 am-6:00 pm Friday, November 11 8:00 am-3:00 pm Need to Know Meals Lunches will be served during Scientific Symposia (Monday), at the opening of the Exhibit Hall (Tuesday), and during lunchtime activities (Wednesday and Thursday). Concession stands will be available throughout the Moscone Center and Exhibit Hall. www . t c t c o n f e r e n c e . c o m 15 ACC and CRF Joint Initiative Joint Conflict of Interest (COI) and Relationship with Industry (RWI) Policies of the Cardiovascular Research Foundation (CRF) and the American College of Cardiology Foundation (ACC) planning the activity) as well as faculty. For a live activity, each faculty is required to check-in upon arrival; and faculty who have not completed their RWI declarations are not allowed to enter the CME activity. For enduring activities, the CME product is not published, either online or in print, until all declarations are completed. CRF/ACC require and collect disclosure of relationships with industry (RWI) from all individuals who are in a position to control or influence educational content. This is done annually in conjunction with all of CRF’s meetings and educational offerings for which CME is offered (including TCT, CRF’s major annual educational event) and all of ACC’s meetings and educational offerings for which CME is offered (including the annual ACC scientific session). All individuals involved in directing, planning, and delivering educational content for CRF and ACC (course directors, planning committee members, faculty, staff, etc) are required to submit RWI disclosures prior to participation; otherwise their participation in the event is precluded. If disclosure of RWI information is not already on file at the inception of a new activity, that information is collected at confirmation of individual participation. This information is also confirmed and updated prior to the development of each CME activity to ensure that the most up-to-date information is collected and available. Likewise, nonphysician staff are required to complete RWI Disclosure Declaration forms. COI Resolution COI (RWI) Declaration The online Required Faculty Disclosure Declaration form requires each individual to identify financial relationships that he or she and/or his or her spouse or partner have had with any organization within the preceding 12 months or that is anticipated in the next 12 months that could be perceived as a relevant conflict of interest. Any individual who does not complete the form is not permitted to participate; this includes course director(s) and planners (who are then excluded from 16 program · Director(s) and planning committee members are required to complete the COI Resolution form prior to content development. In the event that a conflict of interest exists, the activity content is reviewed by course director(s), planning committee members, CME committee members, or designees who do not have conflicts of interest. Speakers, Presenters, Moderators, Panelists, and Live Case Operators who have declared a COI or RWI are required to complete a COI Resolution form online to indicate that they will resolve their conflict(s) by one or more of the following: 1.Confirming that no patient care recommendations will be made to the learners regarding the use of drugs or devices from companies with which they have a financial relationship 2. Confirming that if patient recommendations will be made to the learners regarding the use of drugs or devices from companies with which they have a financial relationship, the conflict will need to be resolved (see next paragraph) 3. Submitting an alternate resolution of the conflict that is then reviewed by the CME Committee, course director(s) and/or planning committee, and if acceptable, approved 4. Recommending an alternate speaker 5. Agreeing to divest themselves of the financial relationship T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Upon receipt of the COI Resolution form, the course director(s), planning committee members, or CME committee members or their designees review each COI Resolution form to determine the course of action, if any, necessary to resolve the conflict. Possible conflict resolution mechanisms, based on the educational design of the program, include using a variety of approaches including, but not limited to: 1. Knowledge of speakers (for example, in the past has the individual participated in unbiased presentations, discussions, published literature, etc) 2. Knowledge of content 3. Interview with speakers 4. Slide peer review 5. Abstract peer review 6. Replacing the presenter For TCT and ACC annual scientific sessions where presentations number in the thousands, a committee is formed to review all faculty financial relationships to determine whether slide review is necessary; if so, slides are reviewed prior to presentation and, when necessary, changes are recommended and implemented. In July 2010, in response to an ACCME update, sessions with industry employee speakers are allowed to be certified under the following circumstances: 1. The presentation is about the scientific or discovery process itself 2. The presentation is about products that have not yet entered the clinical arena (including products that are under investigation) 3. P resentation slides are submitted at least 2 weeks before the start of the CME activity, and the presenter agrees in advance to any and all modifications requested by the CME committee The World’s Premier Interventional Experience TCT2011 Disclosure to Attendees Standard practices to ensure that faculty financial relationships are disclosed to the learners prior to the activity include: 1. Printed disclosure summaries 2. A COI slide prepared by the presenter is inserted at the beginning of the presentation. COI slide templates are e-mailed to all faculty approximately one month prior to the activity. Audiovisual vendors review each presentation to insure that a COI slide has been inserted, and are instructed not to load or confirm the speaker’s presentation without a valid COI slide being present. Additional Policies of the Cardiovascular Research Foundation CRF requires members of the Board of Directors, all employees, and affiliated physicians to disclose on an annual basis any relevant financial interests. The process is managed and the policy is enforced by CRF’s Compliance Oversight Review Committee of the Board of Directors and its Compliance Officer. For the TCT scientific sessions, abstracts are peer-reviewed and if accepted are presented at the meeting and published in the Journal of the American College of Cardiology. Approximately 379 physicians grade the abstracts, more than 80% of whom are TCT Course Directors, Co-directors, or Associate Directors, planning committee members, or faculty, and their Disclosure Declarations are on file. The abstract review process is performed online, is blinded, and requests reviewers to recuse themselves from grading abstracts for which they may have a COI or RWI. Ten reviewers are assigned to grade each abstract, and the high and low scores are discarded. This process T r a n s c at h e t e r Cardiovascular Therapeutics also performed online similar to the abstract review process. For TCT 2011, 25 physicians graded the Late Breaking Trial submissions. As part of the selection process, outlier as well as mean scores are reviewed to confirm that grading is fair. For all live activities except TCT, CRF has mandatory slide review for all individuals, even individuals who attest that (1) recommendations will be based on data and findings from peer-reviewed sources or, in the absence of adequate peer-reviewed material, will rely on the best available evidence based medicine, and (2) content will be fair and balanced, and if any product specific drugs or devices are discussed, alternative drugs or devices will be discussed. Slides are reviewed prior to presentation, and when necessary, changes are recommendedand implemented. Faculty members at all CRF educational events are instructed to verbally communicate to the audience the RWIs displayed on the COI slide. CRF’s audiovisual vendor has developed a system that requires that the COI slide cannot be advanced until a sufficient time has elapsed to allow it to be read by the audience. was selected to mitigate the effect of any one individual who may have a conflict of interest. Late Breaking Clinical Trial review is www . t c t c o n f e r e n c e . c o m 17 Learning Labs and Edited Taped Cases Learning Labs Learning Labs are hands-on interactive training sessions dedicated to creating an intimate educational atmosphere for interaction between physicians and health care professionals and a company’s clinical specialist or a key opinion leader to enhance knowledge and understanding of treatment techniques and devices. Learning Labs are conveniently located in Exhibit Hall with sessions Tuesday through Thursday, November 8-10, during Exhibit Hall hours. Learning Lab Sponsored by Cordis Corporation, a Johnson & Johnson Company Tuesday, November 8 12:00 pm-1:00 pm Experience EXOSEAL™ Workshop: Vascular Closure Patrick A. Cambier, MD 2:30 pm-3:30 pm How to Start a Radial Program Wayne Batchelor, MD, MHS Thursday, November 10 Tuesday, November 8 9:00 am-10:00 am How to Start a Radial Program Wayne Batchelor, MD, MHS Transradial Access and Procedural Anticoagulation Therapies 2:30 pm-3:30 pm 3:30 pm-4:30 pm A Nurse Perspective on Radial Approach Jeanne Kuperberg, RN 10:00 am-11:00 am Experience EXOSEAL™ Workshop: Vascular Closure Patrick A. Cambier, MD 2:00 pm-3:00 pm Experience EXOSEAL™ Workshop: Vascular Closure Patrick A. Cambier, MD 3:30 pm-5:00 pm Complex Radial PCI “Tips and Tricks” Christopher J. Cooper, MD Panel Discussion: How Should I Treat? Adhir R. Shroff, MD, Oliver F. Bertrand, MD, Christian Spaulding, MD Learning Lab Sponsored by Terumo Interventional Systems and The Medicines Company A Nurse Perspective on Radial Approach Jeanne Kuperberg, RN Transradial Access and Procedural Anticoagulation Therapies Wednesday, November 9 Educating for Better Outcome 9:00 am-10:00 am Experience EXOSEAL™ Workshop: Vascular Closure Patrick A. Cambier, MD Through didactic presentations and handson simulator demonstrations, the attendee will have the opportunity to gain exposure and experience in the following areas: radial access, catheter and wire selection for various anatomical situations, tips and tricks, and complex cases review. 12:00 pm-1:30 pm Complex Radial PCI “Tips and Tricks” Christopher J. Cooper, MD Panel Discussion: How Should I Treat? Adhir R. Shroff, MD, Oliver F. Bertrand, MD, Christian Spaulding, MD 2:00 pm-3:00 pm Experience EXOSEAL™ Workshop: Vascular Closure Patrick A. Cambier, MD 3:30 pm-4:30 pm How to Start a Radial Program Wayne Batchelor, MD, MHS In addition, the attendee will learn about hemostasis techniques and comparing the TR Band™ to competitive offerings and why patent hemostasis is preferred along with procedural anticoagulation therapies. This program has been developed in close coordination with Sunil V. Rao, MD, and Adhir R. Shroff, MD, along with a faculty of experienced physicians in radial and anticoagulation solutions. A Nurse Perspective on Radial Approach Jeanne Kuperberg, RN 18 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Wednesday, November 9 Transradial Access and Procedural Anticoagulation Therapies 9:30 am-10:30 am 11:00 am-12:00 pm 1:00 pm-2:00 pm 2:30 pm-3:30 pm 4:00 pm-5:00 pm Thursday, November 10 Transradial Access and Procedural Anticoagulation Therapies 9:30 am-10:30 am 11:00 am-12:00 pm 12:30 pm-1:30 pm Edited Taped Case Presentations Presentation Theater North, Napa Valley (Located in Hall D) A taped case demonstration consists of capturing the following elements of an interventional procedure performed in a cath lab in real time: • Narrated patient history slides and an introduction of the case • A wide shot of the primary operator from across the table narrating the demonstration • A close-up of devices and techniques from the foot of the table • Live imaging capture from flouroscopy, echo, IVUS, etc New to TCT 2011, the Edited Taped Cases Presentations will be presented in the Presentation Theater North (Napa Valley) of the Moscone Center on Wednesday and Thursday, November 9-10. The topics will include FFR, OCT, CHF, CTO, and endovascular interventions. The World’s Premier Interventional Experience CME/CE information CME Accreditation and Designation The Cardiovascular Research Foundation is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Cardiovascular Research Foundation designates this live activity for a maximum of 54.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. One contact hour equals 60 minutes of learning time. This does not include Breakfast Meetings, Evening Symposia, or other specialty programs such as Hands on Hearts. Documentation of awarded credit is provided for registered attendees in exchange for completed online activity evaluations. Certificates of attendance are provided to all registered attendees in their meeting bags. CE Accreditation and Designation The American College of Cardiology Foundation (ACCF) is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation. The ACCF designates TCT 2011 educational activity for a maximum of 54.75 contact hours. Requirements for successful completion are attendance at TCT 2011 and completing the evaluation tool. Each nurse/nurse practitioner attendee may only claim a maximum of 54.75 contact hours, commensurate with the extent of their separate or combined successful completion in the activities. Non-Endorsement of Products Accredited status does not imply endorsement by the American Nurses Credentialing Center or the American College of Cardiology Foundation of any commercial products displayed in conjunction with this activity. Off-Label Use ACCF requires that all faculty disclose their intent to discuss any unlabeled/unapproved uses of drugs and/or devices during their presentations. Learning Objectives By the end of this symposium, participants should be able to: •Discuss the results from important clinical trials and evidence-based medicine to guide management of patients with atherosclerosis and structural heart disease •Incorporate new interventional technologies and procedures into the care of patients with complex coronary and endovascular disease •Integrate advances in diagnostic evaluation and therapeutics to patients with carotid and peripheral arterial disease •Describe appropriate pharmacologic management in the care of patients undergoing diagnostic arteriography and interventional therapies before, during, and after catheterization Target Audience This symposium is designed for interventional cardiologists, radiologists, clinical cardiologists, basic scientists, vascular medicine specialists, surgeons, nurses, cath lab technicians, and other health care professionals with a special interest in the field of interventional and vascular medicine. Activity Evaluation Online evaluation will address content, presentation, possible bias, and future educational needs. TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Disclosure Statement It is the policy of the Cardiovascular Research Foundation to ensure balance, independence, objectivity, and scientific rigor in all of its sponsored educational activities. Commercial support from industry does not influence educational content, faculty selection, and/or faculty presentations, and, therefore, does not compromise the scientific integrity of the educational activity. Discussion of off-label product usage and/ or off-label product use during live cases is made at the sole discretion of the faculty. Off-label product discussion and usage are not endorsed by the Cardiovascular Research Foundation or the conference directors of this activity. Faculty/planners participating in continuing medical education activities sponsored by the Cardiovascular Research Foundation are required to disclose to the activity audience any real or apparent conflicts of interest related to the content of their presentations. Faculty/planners not complying with this policy are not permitted to participate in this activity. Program Sponsorship This symposium is sponsored by the Cardiovascular Research Foundation. This symposium is co-provided by the American College of Cardiology Foundation. Program Support This symposium is partially funded through educational grants from commercial supporters. The Cardiovascular Research Foundation ensures that its programs are educational and meet the needs of the target audience. To support this endeavor, the directors and co-directors of TCT create organizational and scientific committees to assist in educational content development and content oversight for live cases, concurrent sessions, case reviews, abstract sessions, practical workshops, and scientific symposia. These sessions are developed without influence from commercial supporters. www . t c t c o n f e r e n c e . c o m 19 TCT 2011 awards TCT 2011 Awards Please join us in the Main Arena for the presentation of the following awards: TCT Career Achievement Award Wednesday, November 9 at 11:15 am Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award Geoffrey O. Hartzler Master Clinical Operator Award Friday, November 11 at 10:50 am Thursday, November 10 at 11:00 am 1994 Geoffrey O. Hartzler, MD 2003 David E. Kandzari, MD 2009 Eberhard Grube, MD 1995 David R. Holmes, MD 2004 Farouc Jaffer, MD, PhD 2010 Osamu Katoh, MD 1996 Patrick W. Serruys, MD, PhD 2005 Giuseppe De Luca, MD Takahiko Suzuki, MD 1997 John B. Simpson, MD 2006 Alaide Chieffo, MD 2011 Horst Sievert, MD 1998 Antonio Colombo, MD 2007 Wojciech Wojakowski, MD, PhD 1999 Julio C. Palmaz, MD 2008 Mehdi H. Shishehbor, DO, MPH 2000 Donald S. Baim, MD 2009 Robert A. Byrne, MD 2002 William W. O’Neill, MD 2010 Colin M. Barker, MD 2003 J. Eduardo M.R. Sousa, MD, PhD 2011 Finalists Masaki Awata, MD 2004 Eugene Braunwald, MD Davide Capodanno, MD 2005 James T. Willerson, MD Robert W. Yeh, MD Thomas T. Tsai, MD 2006 Paul Yock, MD 2007 Barry T. Katzen, MD 2008 Seung-Jung Park, MD 2009 Spencer B. King III, MD 2010 Alain G Cribier, MD 2011 Eric J. Topol, MD 20 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Hideo Tamai, MD www . t c t c o n f e r e n c e . c o m 21 FRIDAY, 11/11 THURSDAY, 11/10 WEDNESDAY, 11/9 TUESDAY, 11/8 MONDAY, 11/7 SUNDAY, 11/6 am Breakfast Meetings Breakfast Meetings Breakfast Meetings Breakfast Meetings 7:30 am am 9:00 am 9:30 am 10:00 am 10:30 am 11:00 pm 1:00 pm 1:30 pm 2:00 pm 2:30 TCT for Surgeons Scientific Symposia Presentation Theaters pm 3:30 pm 4:00 pm 4:30 How to Treat Theater: Endovascular Disease Learn the Technique Lunchtime Sessions TCT for Surgeons Challenging Case Multiplex Spotlight Sessions Hot Topic Lunchtime Sessions Learn the Technique Lunchtime Sessions Exhibit Hall Presentation Theaters FDA Town Hall Meeting How to Treat Theater: Endovascular Disease How to Treat Theater: Coronary Artery Disease Challenging Case Multiplex Main Arena How to Treat Theater: Endovascular Disease Spotlight Sessions Main Arena Challenging Case Multiplex Spotlight Sessions How to Treat Theater: Structural Heart Disease How to Treat Theater: Coronary Artery Disease Maintenance of Certification (MOC) Session TCT for Surgeons Challenging Case Multiplex Exhibit Hall Spotlight Sessions Challenging Case Multiplex Spotlight Sessions Presentation Theaters How to Treat Theater: Coronary Artery Disease Hot Topic Lunchtime Sessions How to Treat Theater: Structural Heart Disease Exhibit Hall TCT for Surgeons Scientific Symposia pm 5:30 pm 6:00 pm 6:30 pm 7:00 Exhibit Hall Reception Twilight Sessions Twilight Sessions Twilight Sessions pm 7:30 Twilight Sessions Registration: All Attendees and Exhibitors pm 5:00 How to Treat Theater: Coronary Artery Disease Main Arena Lunch in Exhibit Hall Maintenance of Certification (MOC) Session pm 3:00 Registered Cardiovascular Invasive Specialists (RCIS) Review Course Self-Assessment for Interventional Cardiology (Part 2) Oral Abstracts 20th Annual Nurse and Technologist Symposium TCT for Surgeons Poster Abstracts pm 12:30 Registration: All Attendees and Exhibitors pm 12:00 Self-Assessment for Interventional Cardiology (Part 1) am 11:30 20th Annual Cardiovascular Nurse and Technologist Symposium am 8:30 How to Treat Theater: Structural Heart Disease am 8:00 Week at a Glance 7:00 TCT2011 pm 8:00 pm 9:00 pm 9:30 Evening Programs Evening Programs Evening Programs Evening Programs pm 8:30 THE MOSCONE CENTER SAN FRANCISCO, CA November 7-11, 2011 C A R D I O VA S C U L A R RESEARCH F O U N D AT I O N A Passion for Innovation Pioneering New Therapies for the Treatment of Heart Disease More than 81 million people live with heart disease worldwide. Many of them will benefit from interventional procedures developed or refined by the Cardiovascular Research Foundation (CRF) . . . . WE INVESTIGATE Early Stage Technologies During Preclinical Research WE EVALUATE Promising New Therapies by Designing and Implementing Multiple Phases of Human Clinical Trials WE EDUCATE Medical Professionals and the Public to Enhance Patient Outcomes Visit us at the Partnership Pavilion on the first floor of Moscone North. International Faculty Alexandre Abizaid, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Antonio L. Bartorelli, MD University of Milan Milan, Italy Stephen J.D. Brecker, MD St. George’s Hospital London, United Kingdom Paulo Caramori, MD, PhD Hospital São Lucas-PUCRS Porto Alegre, Brazil Andrea Abizaid, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Jozef Bartunek, MD, PhD Cardiovascular Center, OLV Hospital Aalst, Belgium Carlo Briguori, MD, PhD Clinica Mediterranea Naples, Italy Mauro Carlino, MD San Raffaele Hospital Milan, Italy Sergey A. Abugov, ScD BV Petrovsky Russian Centre of Science of Surgery Moscow, Russia Jeroen J. Bax, MD Leiden University Medical Center Leiden, The Netherlands Fabio S. Brito, MD, PhD Albert Einstein Hospital São Paulo, Brazil Didier Carrie, MD, PhD Hôpital de Ranueil Toulouse, France Kevin J. Beatt, MBBS, PhD Mayday University Hospital London, United Kingdom Miroslav Brtko, MD Charles University Prague Hradec Kralove, Czech Republic Luiz Antonio Carvalho, MD Hospital Pro-Cardiaco S/A Rio de Janeiro, Brazil Jorge A. Belardi, MD Instituto Cardiovascular de Buenos Aires Buenos Aires, Argentina Elchanan Bruckheimer, MBBS Schneider Children’s Medical Center Petach Tikva, Israel Graham A. Cassel, MD Milpark Hospital Johannesburg, South Africa Ivo Bernat, MD University Hospital Pilsen Pilsen, Czech Republic Gill L. Buchanan, MD San Raffaele Scientific Institute Milan, Italy Renzo Cecere, MD McGill University Health Centre Montreal, Canada Daniel H. Berrocal, MD Hospital Italiano de Buenos Aires Buenos Aires, Argentina Wacin Buddhari, MD King Chulalongkorn Memorial Hospital Bangkok, Thailand Pavel Cervinka, MD, PhD Masaryk Hospital Ústí nad Labem, Czech Republic Colin Berry, BSc, MBChB, PhD Golden Jubilee National Hospital Glasgow, United Kingdom Lutz Buellesfeld, MD Bern University Hospital Bern, Switzerland Albert W. Chan, MD Royal Columbian Hospital New Westminster, Canada Olivier F. Bertrand, MD, PhD Institut Universitaire de Cardiologie et de Pneumologie de Québec Quebec City, Canada Siro Buendia, MD Son Espases Palma de Mallorca Palma de Mallorca, Spain Charles Chan, MD Gleneagles Medical Centre Singapore Christopher E. Buller, MD St. Michael’s Hospital Toronto, Canada Asim Cheema, MD St. Michael’s Hospital Toronto, Canada Rafael Beyar, MD, DSc Rambam Medical Center Haifa, Israel Francesco Burzotta, MD Institute of Cardiology, Catholic University of the Sacred Heart Rome, Italy Shao Liang Chen, MD Nanjing First Hospital of Nanjing Medical Center Jiangsu, China Henning Rud Andersen, MD University of Aarhus Aarhus, Denmark Giancarlo Biamino, MD, PhD Clinica Montevergine Mercogliano, Italy Jacques Busquet, MD Clinique Chirurgicale Val d’Or Paris-Saint Cloud, France YunDai Chen, PhD Chinese PLA General Hospital Beijing, China David Antoniucci, MD Careggi Hospital Florence, Italy Klaudija Bijuklic, MD Hamburg University Cardiovascular Center Hamburg, Germany Pawel E. Buszman, MD, PhD American Heart of Poland Katowice, Poland Anson Cheung, MD St. Paul’s Hospital Vancouver, Canada Robert A. Byrne, MB, BCh Deutsches Herzzentrum Munich, Germany Bernard R. Chevalier, MD Institut Cardiovasculaire Paris Sud Massy, France Adriano Caixeta, MD, PhD Hospital Israelita Albert Einstein São Paulo, Brazil Paul T.L. Chiam, MD National Heart Center Singapore Singapore Alisson L. Calver, MD, MBBS, MD Wessex Cardiothoracic Centre Southampton, United Kingdom Alaide Chieffo, MD San Raffaele Scientific Institute Milan, Italy Edoardo Camenzind, MD University Hospital of Geneva Geneva, Switzerland Kenneth Chin, MBBS Pantai Hospital Kuala Lumpur, Malaysia Marcelo Jose de Carvalho Cantarelli, MD, PhD Bandeirantes Hospital São Paulo, Brazil Yoon Sin Chong, MD Serdang Hospital Kajang, Malaysia Takashi Akasaka, MD, PhD Wakayama Medical University Wakayama, Japan Remo Albiero, MD Clinica San Rocco di Franciacorta Brescia, Italy Bagrat Alekyan, MD Bakoulev Center for Cardiovascular Surgery/RAMS Moscow, Russia Dimitrios Alexopoulos, PhD Patras University Hospital Patras, Greece Fernando Alfonso, MD, PhD Hospital Universitario San Carlos Interventional Cardiology Madrid, Spain Yaron Almagor, MD Shaare Zedek Medical Center Jerusalem, Israel Ibrahim R. Al-Rashdan, MD Chest Disease Hospital, Ministry of Health Safat, Kuwait Aleksander Araszkiewicz, MD Poznan University of Medical Sciences Poznan, Poland Magaly Arrais dos Santos, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Yasushi Asakura, MD Toyohashi Heart Center Toyohashi, Japan Panayiotis Avraamides, MD Cyprus Society of Cardiology Nicosia, Cyprus Masaki Awata, MD Kansai Rosai Hospital Amagasaki, Japan Vinay K. Bahl, MD, DM All India Institute of Medical Sciences New Delhi, India Amal Kumar Banerjee, MD, DM Advanced Medical Research Institute Kolkata, India Adrian P. Banning, MD John Radcliffe Hospital Oxford, United Kingdom Mauricio R. Barbosa, MD Biocor Hospital Nova Lima, Brazil 24 program · Otavio Berwanger, MD São Paulo Cardiac Hospital São Paulo, Brazil Josef Bis, MD Charles University Prague Hradec Kralove, Czech Republic Daniel J. Blackman, MD Leeds General Infirmary Leeds, United Kingdom Wolfgang Bocksch, MD, PhD Tubingen University Hospital Tubingen, Germany Jose Ary Boechat, MD Sociedade Brasileira de Hemodinâmica e Cardiologia Intervencionista Rio de Janeiro, Brazil Raoul Bonan, MD Montreal Heart Institute Montreal, Canada Laurent Bonello, MD Hôpital Universitaire Nord Marseille, France Sarana Boonbaichaiyapruck, MD Ramathibodi Hospital, Mahidol University Bangkok, Thailand Alessandro S. Bortone, MD, PhD Interventional Lab Cardiac Surgery University of Bari Bari, Italy T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Warren J. Cantor, MD Southlake Regional Health Center Newmarket, Canada Davide Capodanno, MD Ferrarotto Hospital Catania, Italy Piera Capranzano, MD Ferrarotto Hospital Catania, Italy Evald H. Christiansen, PhD Aarhus University Hospital Aarhus, Denmark Sanjay Kumar Chugh, MD, DM Fortis Escorts Heart Institute New Delhi, India Bimmer E. Claessen, MD, PhD University of Amsterdam Academic Medical Center Amsterdam, The Netherlands The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Eric A. Cohen, MD Sunnybrook Health Sciences Centre Toronto, Canada Giuseppe De Luca, MD Eastern Piedmont University Novara, Italy David Erlinge, MD, PhD Lund University Hospital Lund, Sweden Hector M. Garcia-Garcia, MD, PhD Thoraxcenter, Erasmus Medical Center Rotterdam, The Netherlands Antonio Colombo, MD Columbus Hospital/San Raffaele Hospital Milan, Italy Muzaffer Degertekin, MD, PhD Yeditepe University Istanbul, Turkey Aleksander Ernst, MD, PhD Clinical Hospital Center Zagreb Zagreb, Croatia Jorge Gaspar, MD National Institute of Cardiology Mexico City, Mexico Stéphane Cook, MD Swiss Cardiovascular Center Fribourg, Switzerland Peter den Heijer, MD Amphia Hospital Breda Breda, The Netherlands Javier Escaned, MD, PhD Hospital ClÌnico San Carlos Madrid, Spain Efrain Gaxiola, MD Jardines Hospital de Especialidades Jalisco, Mexico Thierry Corcos, MD American Hospital of Paris Neuilly-sur-Seine, France Jean-Pierre Dery, MD, MHS Quebec Heart and Lung Institute Quebec, Canada Miroslaw Ferenc, MD Heart Center Bad Krozingen Bad Krozingen, Germany Lei Ge, MD Shanghai Zhongshan Hospital Shanghai, China Roberto Corti, MD University Hospital Zurich Zurich, Switzerland Walter Desmet, MD Katholieke Universiteit Leuven, Belgium Fausto Feres, MD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Ulrich J. Gerckens, MD Hospitial St. Petrus Bonn, Germany Jose de Ribamar Costa Jr, MD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Carlo Di Mario, MD Royal Brompton Hospital London, United Kingdom Anthony H. Gershlick, MD University of Leicester Leicester, United Kingdom Ricardo A. Costa, MD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Germano Di Sciascio, MD Campus Bio-Medico University Rome, Italy Francisco Fernandez-Aviles, MD, PhD Hospital General Universitario Gregorio Marañón Madrid, Spain Brian Courtney, MD, MSEE Schulich Heart Program Toronto, Canada Stefanie Dimmeler, PhD University of Frankfurt Frankfurt, Germany Bodo Cremers, MD Klinik für Innere Medizin III Homburg, Germany Mirko Doss, MD JW Goethe University Frankfurt Frankfurt, Germany Alain G. Cribier, MD Hôpital Charles Nicolle Rouen, France Henricus J. Duckers, MD, PhD Erasmus Medical Center Rotterdam, The Netherlands Fernando Cura, MD, PhD Instituto Cardiovascular de Buenos Aires Buenos Aires, Argentina Dariusz Dudek, MD, PhD Jagiellonian University Krakow, Poland Nick Curzen, PhD Southampton University Hospitals Southampton, United Kingdom Timothy C. Dy, MD Chinese General Hospital and Medical Center Manila, Philippines Maciej Dabrowski, MD Institute of Cardiology Warszawa, Poland Joost Daemen, MD, PhD Erasmus Medical Center Rotterdam, The Netherlands Sameer Indravadan Dani, MD Apollo Hospital International Ltd. Ahmedabad, India Mikael Danielewicz, MD PCI-unit Karlstad Karlstad, Sweden Justin Davies, MBBS, MRCP, PhD Imperial College London NHS Trust London, United Kingdom Periklis Davlouros, MD Patras University Hospital Patras, Greece Vladimir Dzavik, MD Peter Munk Cardiac Centre, University Health Network Toronto, Canada Franz R. Eberli, MD Triemli Hospital Zurich Zurich, Switzerland Guering Eidt-Lidt, MD Instituto Nacional de Cardiologia Mexico City, Mexico Helene Eltchaninoff, MD Hôpital Charles Nicolle Rouen, France Knut Endresen, MD, PhD Oslo University Hospital Oslo, Norway Mark A. de Belder, MD, MA The James Cook University Hospital Middlesbrough, United Kingdom Thomas Engstrom, MD, DMSci, PhD The Heart Centre, University of Copenhagen Copenhagen, Denmark Bernard De Bruyne, MD, PhD Cardiovascular Center Aalst Aalst, Belgium Raimund A. Erbel, MD University Duisburg-Essen Essen, Germany Antonio Carlos Campos de Carvalho, MD National Cardiology Institute Rio de Janeiro, Brazil Oktay Ergene, PhD State Hospital in Izmir Izmir, Turkey Jose M. de la Torre Hernandez, MD, PhD Hospital Universitario Marques de Valdecilla Santander, Spain Andrejs Erglis, MD, PhD P. Stradins Clinical University Hospital Riga, Latvia Hans R. Figulla, MD Friedrich-Schiller Universitat Jena, Germany Massimo Fineschi, MD Le Scotte Hospital, University Hospital of Siena Siena, Italy Thierry A. Folliguet, MD Institut Mutualiste Montsouris Paris, France Olaf Franzen, MD Rigshospitalet Copenhagen Copenhagen, Denmark Douglas G. Fraser, MD Manchester Heart Centre Manchester, United Kingdom Guosheng Fu, MD Sir Run Run Shaw Hospital Zhejiang, China Xianghua Fu, MD Second Hospital of Hebei Medical University Shijiazhuang City, China Rié Fukaya, MMS Pharmaceuticals and Medical Devices Agency, Japan Tokyo, Japan Anthony Fung, MBBS Vancouver General Hospital Vancouver, Canada Alfredo R. Galassi, MD Ferrarotto Hopsital Catania, Italy Daljeet S. Gambhir, MD, DM Kailash Hospital and Heart Institute New Delhi, India Vladimir Ganyukov, MD Scientific Research Institute for Cardiovascular Diseases Kemerovo, Russia Run-Lin Gao, MD Fu Wai Hospital Beijing, China Eulogio J. Garcia, MD Hospital Clinico San Carlos Madrid, Spain Georges Ghanem, MD Clemenceau Medical Center Beirut, Lebanon Robert J. Gil, PhD Central Clinic Hospital Warsaw, Poland Dietmar H. Glogar, MD University of Vienna Vienna, Austria Matthias Götberg, MD, PhD Skane University Hospital Lund, Sweden Roger M. Greenhalgh, MD Charing Cross Hospital London, United Kingdom Liliana R. Grinfeld, MD CENPEC Buenos Aires, Argentina Ladislav Groch, MD University Hospital St. Anna Brno, Czech Republic Eberhard Grube, MD University Hospital Bonn Bonn, Germany Marek Grygier, MD, PhD University Hospital in Poznan Poznan, Poland Giulio Guagliumi, MD Ospedali Riuniti Di Bergamo Bergamo, Italy Victor Guetta, MD Heart Institute Chaim Medical Center Tel-Hashomer, Israel Vivek Gupta, MD, DM Indraprastha Apollo Hospitals New Delhi, India Maoto Habara, MD Toyohashi Heart Center Toyohashi, Japan Marcelo Halac, MD Hospital Italiano de Buenos Aires Buenos Aires, Argentina Michalis Hamilos, MD University Hospital of Heraklion Crete, Greece Christian W. Hamm, MD Kerckhoff Clinic Bad Nauheim, Germany www . t c t c o n f e r e n c e . c o m 25 International Faculty Martial Hamon, MD University Hospital of Caen Caen, France Keiichi Igarashi, MD, PhD Hokkaido Social Insurance Hospital Sapporo, Japan Osamu Katoh, MD Kusatsu Heart Center Toyohashi, Japan Takashi Kubo, MD, PhD Wakayama Medical University Wakayama, Japan Yaling Han, MD Shenyang Northern Hospital Shenyang, China Koji Ikeda, PhD Pharmaceuticals and Medical Devices Agency Tokyo, Japan Upendra Kaul, MD Fortis Hospital Karnataka, India Karl-Heinz Kuck, MD Asklepios Hospital St. Georg Hamburg, Germany Zaza Kavteladze, MD The Centre of Endosurgery and Lithotripsy Moscow, Russia Sreenivas Arramraju Kumar, MD, DM CARE Hospitals Hyderabad, India Claude Hanet, MD University of Louvain Medical School Brussels, Belgium Jan Harnek, MD, PhD Skane University Hospital Lund, Sweden Thomas A. Ischinger, MD, PhD Kardiologie im Zentrum Munich, Germany Michael Haude, MD Lukaskrankenhaus Neuss Neuss, Germany Gonzague Issenmann Stentys Paris, France Paul J. Hauptman, MD BioControl Medical Yehud, Israel Christoph Hehrlein, MD University Hospital Freiburg Freiburg, Germany Stefan K. James, MD Uppsala Clinical Research Center, Uppsala University Hospital Uppsala, Sweden Lars Hellsten, MD Landstinget Gävleborg Gävle, Sweden Yang-Soo Jang, PhD Yonsei University Health System Seoul, South Korea Jose P.S. Henriques, MD, PhD Academic Medical Center Amsterdam, The Netherlands Lisette Okkels Jensen, MD, DMSci, PhD Odense University Hospital Odense, Denmark Michel Henry, MD Cabinet de Cardiologie Nancy, France Ulf Jens Jensen, MD Karolinska University Hospital Stockholm, Sweden Yudi Her Oktaviono, MD Dr Hospital Soetomo Surabaya, Indonesia Young-Hoon Jeong, MD, PhD Gyeongsgang National University Hospital Jinju, South Korea Felipe Hernandez, MD Hospital 12 de Octubre Madrid, Spain Elvin Kedhi, MD Maasstad Ziekenhuis Rotterdam, The Netherlands Henning Kelbaek, MD Rigshospitalet Kobenhavn, Denmark Thomas Kellerth, MD Örebro University Hospital Örebro, Sweden Joerg Kempfert, MD Kerckhoff Clinic Bad Nauheim Bad Nauheim, Germany Hyo-Soo Kim, MD, PhD Seoul National University Hospital Seoul, South Korea Young-Hak Kim, PhD Asan Medical Center Seoul, South Korea Masashi Kimura, MD Toyohashi Heart Center Toyohashi, Japan Takeshi Kimura, MD Kyoto University Hospital Sakyo-ku, Japan Indulis Kumsars, MD Pauls Stradins Clinical University Hospital Riga, Latvia Vincent On-Hing Kwok, MD Hong Kong Sanatorium & Hospital Hong Kong, China Jean-Claude Laborde, MD St George’s Hospital London, United Kingdom Antoine Lafont, MD Hôpital European Georges Pompidou Paris, France Irene M. Lang, MD University of Vienna Vienna, Austria Rudiger Lange, MD, PhD German Heart Center Munich Munich, Germany Jens Flensted Lassen, MD, PhD Aarhus University Hospital Aarhus, Denmark Azeem Latib, MB, BCh EMO Cuore Columbus Milan, Italy Florin Laubenthal, MD Alfried Krupp Krankenhaus Essen, Germany Nigel Jepson, MD Prince of Wales Hospital Sydney, Australia Pawel Kleczynski, MD, PhD University Hospital in Krakow Krakow, Poland Gillian A. Jessurun, MD, PhD, MBA Scheper Ziekenhuis Emmen Emmen, The Netherlands Merril L. Knudtson, MD Libin Cardiovascular Institute of Alberta Calgary, Canada Jonathan M. Hill, MD, MRCP King’s College Hospital London, United Kingdom Sanjit S. Jolly, MD McMaster University Hamilton, Canada Karel T. Koch, MD, PhD Academic Medical Center Amsterdam Amsterdam, The Netherlands Jose Luis Lazaro Castillo, MD Hospital General Centro Médico Nacional La Raza Mexico City, Mexico Lynne Hinterbuchner, RN, DGKS Salzburg University Hospital Salzburg, Austria Michael Joner, MD Deutsches Herzzentrum München Munich, Germany Viktor Kocka, MD Charles University Praque Prague, Czech Republic Michel R. Le May, MD University of Ottawa Heart Institute Ottawa, Canada Andrew Holden, MD Auckland City Hospital Auckland, New Zealand Jeffrey B. Jump Biosensors International Morges, Switzerland Tian-Hai Koh, MD National Heart Center Singapore Guy LeClerc, MD Centre Hospital Universitaire de Montreal Montreal, Canada Stephen P. Hoole, MD Papworth Hospital Cambridge, United Kingdom Peter Juni, MD University of Bern Bern, Switzerland Bon-Kwon Koo, MD, PhD Seoul National University Hospital Seoul, South Korea Michael Kang-Yin Lee, MBBS Queen Elizabeth Hospital Kowloon, Hong Kong Eric Horlick, MD, CM University Health Network Toronto General Hospital Toronto, Canada Christoph A. Kaiser, MD University Hospital Basel Basel, Switzerland Jacques J. Koolen, MD, PhD Catharina Hospital Eindhoven, The Netherlands Thierry Lefevre, MD Institut Hospitalier Jacques Cartier Massy, France Angela Hoye, MD, PhD Castle Hill Hospital Kingston-upon-Hull, United Kingdom Petr Kala, MD, PhD University Hospital and Medical Faculty Masaryk University Brno, Czech Republic Ran Kornowski, MD Rabin Medical Center Petach Tikva, Israel Jorge H. Leguizamon, MD Argentine Society of Interventional Cardiology Buenos Aires, Argentina Kurt Huber, MD Wilhelminen Hospital Vienna, Austria Soo-Jin Kang, MD Asan Medical Center Seoul, South Korea Ioannis (John) Iakovou, MD, PhD Onassis Cardiac Surgery Center Athens, Greece A. Pieter Kappetein, MD, PhD Thoraxcenter Rotterdam, The Netherlands David J. Hildick-Smith, MD Sussex Cardiac Centre, Brighton and Sussex University Hospitals Brighton, United Kingdom 26 Dan Ioanes, MD Sahlgrenska University Hospital Gothenburg Gothenburg, Sweden program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Jan Kovac, MD University Hospital of Leicester Leicester, United Kingdom Hans Krankenberg, MD Medical Care Center Hamburg, Germany Henry Krum, MBBS, PhD Monash University Victoria, Australia Sandra Lauck, MSN St. Paul’s Hospital Vancouver, Canada Jonathon A. Leipsic, MD St. Paul’s Hospital Vancouver, Canada Jose L. Leiva-Pons, MD Hospital Central San Luis Potosi, Mexico Pedro A. Lemos, MD, PhD University of São Paulo Medical School São Paulo, Brazil The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Jonathan Leor, MD Sheba Medical Center Tel-Hashomer, Israel Massimo Mancone, MD Umberto I Hospital Rome, Italy Friedrich W. Mohr, MD, PhD Heart Center Leipzig Leipzig, Germany Jacob Odenstedt, MD, PhD University of Gothenburg Gothenburg, Sweden Maciej Lesiak, MD, PhD University Hospital Poznan, Poland Jose Armando Mangione, MD BeneficÍncia Portuguesa Hospital São Paulo, Brazil Marie-Angele Morel, BSc Cardialysis B.V. Rotterdam, The Netherlands Takao Ohki, MD, PhD Jikei University School of Medicine Tokyo, Japan Thorsten Lewalter, MD Isar Heart Center Munich, Germany Ganesh Manoharan, MD Royal Victoria Hospital Belfast, United Kingdom Marie-Claude Morice, MD Institut Cardiovasculaire Paris Sud Massy, France Hiroyuki Okura, MD Kawasaki Medical School Kurashiki, Japan Lang Li, MD, PhD Guangxi Medical University Nanning, China Isabelle Martin Minvasys Gennevilliers, France Ralf Mueller, MD HELIOS Klinikum Siegburg Siegburg, Germany Shu-Kin Li, MD College of Cardiology Chai Wan, Hong Kong Martin Mates, PhD Na Homolce Hospital Prague, Czech Republic Ajit Mullasari, MD, DM, DNB Madras Medical Mission Hospital Chennai, India Keith G. Oldroyd, MD West of Scotland Regional Heart and Lung Centre Glasgow, Scotland Berglind Libungan, MD Sahlgrenska University Hospital Göteborg, Sweden Samuel K. Mathew, MD, DM Apollo Hospitals Chennai, India Michael J. Mullen, MD University College Hospital London London, United Kingdom Valter C. Lima, MD, PhD Hospital São Francisco - ISCMPA Porto Alegre, Brazil Detlef G. Mathey, MD Hamburg University Cardiovascular Center Hamburg, Germany David W.M. Muller, MBBS, MD St. Vincent’s Hospital Darlinghurst, Australia Thosaphol Limpijankit, MD Ramathibodi Hospital Bangkok, Thailand Axel Linke, MD University of Leipzig Heart Center Leipzig, Germany Jian Liu, MD Peking University People’s Hospital Beijing, China Xuebo Liu, MD East Hospital, Tongji University Shanghai, China Hugo F. Londero, MD Sanatorio Allende-Cordoba Cordoba, Argentina Chaim S. Lotan, MD Hadassah University Hospital Jerusalem, Israel Shuzheng Lu, MD Beijing An Zhen Hospital Beijing, China Georg Lutter, MD, PhD University Hospital Schleswig-Holstein Kiel, Germany Rhona MacDonald, DPhil Mercy Angiography Unit Auckland, New Zealand Sumaira Macdonald, MBChB, PhD Freeman Hospital Newcastle upon Tyne, United Kingdom Lindsay S. Machan, MD Vancouver Hospital & Health Sciences Center Vancouver, Canada Ahmed Magdy, MD National Heart Institute in Cairo Cairo, Egypt Felix Mahfoud, MD Klinik für Innere Medizin III Homburg/Saar, Germany Elsayed Mahmoud Egypt Francesco Maisano, MD San Raffaele Hospital Milan, Italy Talib Majwal, MD Dubai Heart Center Hospital Dubai, United Arab Emirates Jorge Antonio Mayol Almera, MD Universidad de la República Montevideo, Uruguay Margaret B. McEntegart, MD Golden Jubilee National Hospital Glasgow, United Kingdom Julinda Mehilli, MD Deutsches Herzzentrum und Medizinische Klinik der Technischen Universitat Munchen Munich, Germany Ashwin Balachand Mehta, MD Jaslok Hospital Mumbai, India Shamir R. Mehta, MD, MSc Hamilton Health Sciences Hamilton, Canada Bernhard Meier, MD Swiss Cardiovascular Center Bern Bern, Switzerland Oscar A. Mendiz, MD Fundacion Favaloro Buenos Aires, Argentina Maurizio Menichelli, MD Spaziani Hospital Frosinone Frosinone, Italy Ajit Menon, MD, DM Lilavathi Hospital Mumbai, India Ian T. Meredith, MBBS, PhD Monash Medical Centre Clayton Melbourne, Australia Antonio Micari, MD Maria Eleonora Hospital Palermo, Italy Ghada W. Mikhail, MD Imperial College Healthcare London, United Kingdom Erich Minar, MD Medical University Vienna Vienna, Austria Neil E. Moat, MD Royal Brompton Hospital London, United Kingdom Rosli Mohd Ali, MD National Heart Institute Kuala Lumpur, Malaysia Goran K. Olivecrona, MD, PhD Skane University Hospital Lund, Sweden Eustaquio Maria Onorato, MD Policlinico Universitario tor Vergata, Rome Gussago, Italy Yoshinobu Onuma, MD Thoraxcenter, Erasmus Medical Center Rotterdam, The Netherlands Brad I. Munt, MD St. Paul’s Hospital Vancouver, Canada Toshiya Muramatsu, MD Saiseikai Yokohama-City Eastern Hospital Yokohama, Japan Christoph K. Naber, MD, PhD Contilia Heart and Vascular Center Essen, Germany Masato Nakamura, MD Toho University Ohashi Medical Center Tokyo, Japan Sunao Nakamura, MD, PhD New Tokyo Hospital Chiba, Japan John A. Ormiston, MB, ChB Mercy and Auckland City Hospitals Auckland, New Zealand Alexander G. Osiev, MD State Research Institute of Circulation Pathology Novosibirsk, Russia Miodrag C. Ostojic, MD, PhD Clinical Centre of Serbia Belgrade, Serbia Ali Oto, MD Hacettepe University Hospital Ankara, Turkey Dev B. Pahlajani, MD Breach Candy Hospital Mumbai, India Massimo Napodano, MD Padova University Hospital Padova, Italy Alejandro O. Palacios, MD Instito Dupuytren Buenos Aires, Argentina Milan A. Nedeljkovic, MD Clinical Center of Serbia Belgrade, Serbia Matti Jaakko Niemela, MD University of Oulu Oulu, Finland Tullio Palmerini, MD Istituto di Cardiologia/ Universita di Bologna Bologna, Italy Christoph A. Nienaber, MD, PhD University of Rostock Rostock, Germany Keyur H. Parikh, MD Heart Care Clinic Ahmedabad, India Eugenia Nikolsky, MD, PhD Rambam Medical Center Haifa, Israel Jai-Wun Park, MD Asklepios Kliniken Hamburg, Germany Stephane Noble, MD Hùpitaux Universitaires de Genéve Geneva, Switzerland Seung-Jung Park, MD, PhD Asan Medical Center Seoul, South Korea James Nolan, MD, MB, ChB University Hospital North Staffordshire Stoke on Trent, United Kingdom Radoslaw Parma, MD, PhD Medical University of Silesia Katowice, Poland Gilberto Lahorgue Nunes, MD, PhD Hospital Mae de Deus Porto Alegre, Brazil Guido Parodi, MD Careggi Hospital Florence, Italy Andrzej J. Ochala, MD University Hospital Katowice, Poland Tejas Patel, MD, DM TCVS Pvt Ltd Ahmedabad, India Masahiko Ochiai, MD, PhD Showa University Northern Yokohama Hospital Kanagawa, Japan Carlos Pedra, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil www . t c t c o n f e r e n c e . c o m 27 International Faculty Giovanni B. Pedrazzini, MD Cardiocentro Ticino Lugano, Switzerland Evelyn S. Regar, MD, PhD Erasmus Medical Center Rotterdam, The Netherlands Teguh Santoso, MD, PhD Medistra Hospital Jakarta, Indonesia Marco A. Perin, MD, PhD Hospital Albert Einstein Sao Paulo, Brazil Bernhard Reimers, MD Ospedale di Mirano Mirano, Italy Gennaro Sardella, MD Policlinico Umberto I University Rome, Italy Anna Sonia Petronio, MD Ospedale di Cisanello Pisa, Italy Expedito E. Ribeiro, MD, PhD The Heart Institute/ University of São Paulo São Paulo, Brazil Rogerio Sarmento-Leite, MD, PhD Instituto de Cardiologia do Rio Grande do Sul Porto Alegre, Brazil Flavio L. Ribichini, MD Università di Verona Verona, Italy Kazuhiro Sase, MD, PhD Juntendo University Medical Center Tokyo, Japan Gert Richardt, MD, PhD Heart Center, Segeberger Kliniken Bad Segeberg, Germany Erick Schampaert, MD Hopital du Sacre-Coeur de Montreal Montreal, Canada Stéphane Rinfret, MD, SM Quebec Heart and Lung Institute Quebec City, Canada Dierk Scheinert, MD Park-Krankenhaus Leipzig Leipzig, Germany Gilles Rioufol, MD, PhD Hospices Civils de Lyon, Cardiovascular Hospital Bron, France Bruno Scheller, MD Universitatsklinikum des Saarlandes Homburg, Germany Nicolo Piazza, MD German Heart Center Munich, Germany Philippe Pibarot, DVM, PhD Quebec Heart and Lung Institute Quebec City, Canada Jan J. Piek, MD University of Amsterdam Amsterdam, The Netherlands Ruben A. Piraino, MD Sanatorio Plaza Rosario, Argentina Stuart J. Pocock, PhD London School of Hygiene and Tropical Medicine London, United Kingdom Antonios A. Polydorou, MD Evangelismos Hospital Athens, Greece Francesco Prati, MD San Giovanni Hospital Rome, Italy Piotr Pysz, MD Medical University of Silesia Katowice, Poland Shubin Qiao, MD Beijing Fuwai Hospital Beijing, China Marcelo Queiroqa, MD Cardiocenter Centro de Diag e Trat das Doenças João Pessoa, Brazil Sam Radhakrishnan, MD Schulich Heart Center, Sunnybrook Hospital Toronto, Canada Maria D. Radu, MD The Heart Centre, Rigshospitalet Copenhagen, Denmark Homero A. Ramirez, MD Hospital de Cardiologia Instituto Mexicano del Seguro Social Mexico City, Mexico Sudhir Rathore, MD St Georges Hospital London, United Kingdom Krzysztof Reczuch, MD, PhD Wojskowy Szpital Kliniczy Wrocław, Poland 28 program · Robert Roberts, MD University of Ottawa Heart Institute Ottawa, Canada Josep Rodes-Cabau, MD Quebec Heart and Lung Institute/ Laval University Quebec, Canada Alexey Protopopov, MD Krasnoyarsk Regional Cardiovascular Center Krasnoyarsk, Russia Simon Redwood, MD St Thomas’ Hospital London, United Kingdom Harald Rittger, MD Universitätsklinikum Erlangen Erlangen, Germany Wolfgang Schillinger, MD Universitatsmedizin Gottingen Gottingen, Germany Joachim Schofer, MD Hamburg University Cardiovascular Center Hamburg, Germany Peter Sick, MD Krankenhaus Barmherzige Brüder Regensburg Regensburg, Germany Horst Sievert, MD, PhD CardioVascular Center Frankfurt, Sankt Katharinen Frankfurt, Germany Ulrich Sigwart, MD University of Geneva Geneva, Switzerland Sigmund Silber, MD Heart Center at the Isar Munich, Germany Tabassome Simon, MD, PhD Hospital St. Antoine UPMC Paris, France Ajay Radheshyam Sinhal, MBBS, MD, DM Flinders Medical Centre Adelaide, Australia Dimytri Siqueira, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Peter C. Smits, MD, PhD Maasstad Ziekenhuis Rotterdam, The Netherlands Derek So, MD University of Ottawa Heart Institute Ottawa, Canada Erwin Schroeder, MD UCL de Mont-Godinne Yvoir, Belgium Mohamed Sobhy, MD Alexandria University Alexandria, Egypt Gerhard C. Schuler, MD Herzzentrum Leipzig Leipzig, Germany Amanda G.M.R. Sousa, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Karl-Ludwig Schulte, MD, PhD Ev Hospital Königin Elisabeth Herzberge Berlin, Germany Konstantinos Spargias, MD, PhD Hygeia Hospital Athens, Greece Alessandro Sciahbasi, MD Policlinico Casilino - ASL RMB Rome, Italy Christian M. Spaulding, MD, PhD Cochin Hospital/Cordis Issy-les-Moulineaux, France Amit Segev, MD Chaim Sheba Medical Center Tel Hashomer, Israel Eugenio Stabile, MD, PhD Clinica Montevergine Mercogliano, Italy Jacques Seguin, MD CoreValve Paris, France Rod H. Stables, MA, DM Liverpool Heart and Chest Hospital Liverpool, United Kingdom Patrick W. Serruys, MD, PhD Thoraxcenter Rotterdam, The Netherlands Boris Starcevic, MD Clinical Hospital Dubrava Zagreb, Croatia Francesco Saia, MD, PhD Policlinico S. Orsola-Malpighi Bologna, Italy Ashok Seth, DSc Escorts Heart Institute and Research Centre New Delhi, India Christodoulos I. Stefanadis, MD University of Athens Athens, Greece Shigeru Saito, MD Shonan Kamakura General Hospital Kanagawa, Japan Hiroki Shiomi, MD Kyoto University Hospital Kyoto, Japan Luigi Salemme, MD Montevergine Clinic Naples, Italy Junya Shite, MD Kobe University Hyogo, Japan Archimides Sanati, MD Tehran University of Medical Sciences Tehran, Iran Georgios Sianos, MD, PhD AHEPA University Hospital Thessaloniki, Greece Giuseppe M. Sangiorgi, MD University of Rome tor Vergata Rome, Italy Dirk Sibbing, MD Deutsches Herzzentrum Munchen Munich, Germany Alfredo Rodriguez, MD, PhD Sanatorio Otamendi Buenos Aires, Argentina Enrico Romagnoli, MD, PhD Policlinico Casilino Rome, Italy Peter N. Ruygrok, MD Auckland City Hospital Grafton, New Zealand Jamil Abdalla Saad, MD Fundação Felisse Rosso Belo Horizonte, Brazil Manel Sabate, MD, PhD Thorax Institute, Hospital Clinic Barcelona, Spain Stefan Sack, MD Klinikum Schwabing Munich, Germany T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Terje K. Steigen, MD, PhD University Hospital of Northern Norway Tromso, Norway Pieter R. Stella, MD, PhD University Medical Center Utrecht Utrecht, The Netherlands Jason Stewart, MD Västra Götalandsregionen Vänersborg, Switzerland Roman Stipal, MD University Hospital Olomouc, Czech Republic Bradley H. Strauss, MD, PhD Sunnybrook Health Sciences Center Toronto, Canada The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Satoru Sumitsuji, MD Nozaki Tokushukai Hospital/ Osaka University Osaka, Japan Sanjay Tyagi, MBBS, MD, DM G.B. Pant Hospital and Maulana Azad Medical College New Delhi, India Marco V. Wainstein, MD, DSc Hospital de Clinicas de Porto Alegre and Hospital Moinhos de Vento Porto Alegre, Brazil Maarten J. Suttorp, MD, PhD St. Antonius Hospital Nieuwegein, The Netherlands Wasan Udayachalerm, MD King Chulalongkorn Memorial Hospital Bangkok, Thailand Kevin Walsh, MD Our Lady’s Hospital for Sick Children Dublin, Ireland Takahiko Suzuki, MD Toyohashi Heart Center Toyohashi, Japan Yasunori Ueda, MD, PhD Osaka Police Hospital Osaka, Japan Simon Walsh, MD, MRCP Belfast Trust Belfast, United Kingdom Tomoyuki Suzuki, MD Sakakibara Heart Institute Tokyo, Japan Philip M. Urban, MD La Tour Hospital Geneva, Switzerland Darren L. Walters, MBBS, MPhil The Prince Charles Hospital Brisbane, Australia David Taggart, MD, PhD John Radcliffe Hospital Oxford, United Kingdom Gian Paolo Ussia, MD Ferrarotto Hospital Catania, Italy Thomas Walther, MD Kerckhoff Klinik Bad Nauheim Bad Nauheim, Germany Corrado Tamburino, MD, PhD Ferrarotto Hospital Catania, Italy Alec Vahanian, MD Hôpital Bichat Paris, France Haichang Wang, MD Xijing Fourth Military Medical University Xi’an, China Bo Xu, MD Cardiovascular Institute and Fu Wai Hospital Beijing, China Huay Cheem Tan, MD National University Heart Centre Singapore Marco Valgimigli, MD, PhD University of Ferrara, Cardiovasuclar Institute Ferrara, Italy Lefeng Wang, MD Beijing Chaoyang Hospital Beijing, China Masahisa Yamane, MD Sayama Hospital Sayama City, Japan Philip Wang, MBA Microport Shanghai, China Hongbing Yan, MD, PhD Beijing Anzhen Hospital Beijing, China Weiman Wang, MD Peking University People’s Hospital Beijing, China Yuejin Yang, MD, PhD Cardiovascular Institute and Fu Wai Hospital Beijing, China Jean-François Tanguay, MD Montreal Heart Institute Montreal, Canada Jurrien M. Ten Berg, PhD St. Antonius Hospital Nieuwegein, The Netherlands Swee Guan Teo, MD National University Health Centre Singapore Mitsuyasu Terashima, MD Toyohashi Heart Center Toyohashi, Japan Christian Juhl Terkelsen, MD Aarhus University Hospital Skejby, Denmark Holger Thiele, MD University of Leipzig Heart Center Leipzig, Germany Martyn R. Thomas, MD St Thomas’ Hospital London, United Kingdom Leif Thuesen, MD Aarhus University Hospital Aarhus, Denmark Ralph Toelg, MD Herz-Kreislauf-Zentrum Bad Segeberg, Germany Pim A.L. Tonino, MD Catharina Hospital Eindhoven, The Netherlands Konstantinos Toutouzas, MD Athens Medical School Athens, Greece Hendrik Treede, MD University Heart Center Hamburg Hamburg, Germany Dietmar Trenk, PhD Herz-Zentrum Bad Krozingen Bad Krozingen, Germany Uday Trivedi, FRCS, C-Th Royal Sussex County Hospital Brighton, United Kingdom Etsuo Tsuchikane, MD, PhD Toyohashi Heart Center Toyohashi, Japan Heleen van Beusekom, MD Thoraxcenter Erasmus, The Netherlands Frans Van de Werf, MD University of Leuven Leuven, Belgium Isabelle Van Herzeele, MD, PhD University Hospital Ghent Ghent, Belgium Glenn Van Langenhove, MD, PhD, MBA Middelheim Hospital Antwerp Antwerpen, Belgium Nicolas van Mieghem, MD Eramus Medical Center Rotterdam, The Netherlands Hugo Vanermen, MD Onz-Lieve-Vrouw Ziekenhuis Aalst, Belgium Dobrin Vassilev, MD, PhD National Heart Hospital Sofia, Bulgaria Freek W.A. Verheugt, MD Onze Lieve Vrouwe Gasthuis Amsterdam, The Netherlands Stefan Verheye, MD, PhD Antwerp Cardiovascular Institute, Middleheim Hospital Antwerp, Belgium Paul Vermeersch, MD, PhD AZ Middelheim Hove, Belgium Ernst Vester, MD, PhD University of Düsseldorf Düsseldorf, Germany Clemens von Birgelen, MD, PhD Thoraxcentrum Twente Enschede, The Netherlands Jeroen Vos, MD Amphia Hospital Breda Breda, The Netherlands Pascal Vranckx, MD Hartcentrum Hasselt, Belgium Wojciech Wojakowski, MD, PhD Third Division of Cardiology Katowice, Poland Stephen G. Worthley, PhD The University of Adelaide Adelaide, Australia Yongjian Wu, MD Fu Wai Hospital Beijing, China Nina C. Wunderlich, MD CardioVascuar Center Frankfurt Frankfurt, Germany Yusuke Watanabe, MD Institut Cardiovasculaire Paris Sud Paris, France Jian Ye, MD St. Paul’s Hospital Vancouver, Canada John G. Webb, MD St. Paul’s Hospital Vancouver, Canada Hiroyoshi Yokoi, MD Kokura Memorial Hospital Fukuoka, Japan Mark W.I. Webster, MB, ChB Auckland City Hospital Auckland, New Zealand Carlos Zabal, MD Instituto Nacional de CardiologÌa Mexico City, Mexico Peter Wenaweser, MD University Hospital Bern Bern, Switzerland Azfar G. Zaman, MD Freeman Hospital Newcastle Upon Tyne, United Kingdom Olaf Wendler, MD, PhD King’s College Hospital London, United Kingdom Robaayah Zambahari, MBBS National Heart Institute Kuala Lumpur, Malaysia Gerald S. Werner, MD, PhD Klinikum Darmstadt Darmstadt, Germany Robert J. Whitbourn, MBBS, MD, BSc St. Vincent Hospital Melbourne Melbourne, Australia Harvey D. White, DSc Green Lane Cardiovascular Service, Auckland City Hospital Auckland, New Zealand Aaron Wong, MD National Heart Centre Singapore Singapore Andreas M. Zeiher, MD University Hospital Medical Center Frankfurt, Germany Michael Zelizko, MD, PhD Clinic of Cardiology IKEM Praha, Czech Republic Thomas Zeller, MD Herzzentrum Bad Krozingen Bad Kronzingen, Germany Stephan Windecker, MD Swiss Cardiovascular Center Bern Bern, Switzerland Uwe Zeymer, MD Herzzentrum Ludwigshafen Ludwigshafen, Germany Adam Witkowski, MD, PhD Institute of Cardiology Warsaw, Poland Qi Zhang, PhD Shanghai Ruijin Hospital Luwan, China Bernhard Witzenbichler, MD Charite University of Medicine Berlin Berlin, Germany Ruiyan Zhang, PhD Shanghai Ruijin Hospital Shanghai, China Jochen Wöhrle, MD University Hospital Ulm Ulm, Germany Yujie Zhou, MD, PhD Beijing Anzhen Hospital Beijing, China www . t c t c o n f e r e n c e . c o m 29 TCT Advisory Faculty Atul Abhyankar, MD Sunil Eshwarchand Agarwal, MD, DNB Rajiv Agarwal, MD Syed Ali Ahsan, MD Ravikumar Aluri MD Sung Gyu An, Fellow Sambasivam Kalpathi Ananthanarayanan, MD Pedro Beraldo De Andrade, MD Júlio César Machado Andrea, MD Madeswaran Tiruchengode Angappan, MD Syed Ali Anis, MD Nelson Antonio Moura De Araujo, MD José Augusto Rocha Araujo, MD Carlos Augusto Formiga Areas, MD Santiago Raul Arrieta, MD José Airton De Arruda, MD Bedson Jose Lopes De As, MD Safiya Manzil Ashraf, MD, DM Khurshid Aslam, MD Parayoru Kottayil Asokan, MD, DM Lakshmi Narayanan Aswathaman, MD Ravi Kanth Athuluri, MD Thankachan Varkey Attacheril, MD, DM Guilherme Ferragut Attizzani, MD Milind Avdhout, MD, FRCP Harish Somasundaram Ayyappan, MD Ju Yeal Back, MD, PhD Rajeev Bagarhatta, MD Shiv Bagga, MD R. Bagirath, MD Madan Mohan Balakrishnan, MD Profparthasarathi Banerjee, MD Raju Barathithasan, MD Flavio Passos Barbosa, MD Hemang Baxi, MD Leonardo Gogo Beck, MD Mrutyunjaya Behera, MD Abhijit Belgaumkar, MD Nirav Bhalani, MD Naveen Bhambhri, MD Rajeev Bhardwaj, MD Suman Bhandari, MD Jayesh Bhaskaran, MD Gopalkrishna Bhat, MD M. N. Bhat, MD Vineet Bhatia, MD J. S. Bhuvaneswaran, MD Arup Das Biswas, MD Roberto Vieira Botelho, MD Fábio Sândoli De Brito Jr, MD André Farinelli Lima Brito, MD Ronaldo Da Rocha Loures Bueno, MD Jamil Ribeiro Cade, MD Adriano Mendes Caixeta, MD Marcelo José De Carvalho Cantarelli, MD Paulo Ricardo Avancini Caramori, MD Cristiano De Oliveira Cardoso, MD Rajneesh Carlton, MD José Klauber Roger Carneiro, MD Antonio Carlos De Camargo Carvalho, MD Luiz Antonio Ferreira Carvalho, MD Marco Tulio Villaça Castagna, MD Hélio José Castello Jr, MD Marinella Patrizia Centemero, MD Gpcaptds Chadha, MD In-Ho Chae, MD Jei-Keon Chae, MD, PhD Venkateshawara Rao Chaganti, MD Subhash Chana, MD B. B. Chanana, MD Bharat Bhushan Chanana, MD, DM Aniruddha Balkrishna Chandorkar, MD 30 program · Nishith Chandra, MD Gopalan Bahuleyan Charantharayil, MD Mahantesh Rachayya Charantimath, MD S.S. Chatterjee, MD Sanjiv Chaudhary, MD V. C. Chauhan, MD Áurea Chaves, MD Kamaldeep Chawla, MD Wook-Hyun Cho, MD Yun-Kyeong Cho, MD Yunseok Choi, MD, PhD Jae-Woong Choi, MD Arun Chopra, MD Vikas Chopra, MD Wilson Miguel Cecim Coelho, MD Ricardo Alves Da Costa, MD Rodrigo Nieckel Da Costa, MD José Ribamar Costa Jr, MD Luciana Constant Daher, MD Ramakrishna Chengala Damodara, MD, DM Sameer Dani, MD Dinyar Daruwala, MD Rubens Zenobio Darwich, MD Arvind Das, MD Mrinal Kanti Das, MD Ajit Desai, MD Devang Desai, M.D Rajendra Govindrao Deshmukh, MBBS, MD, DnB Shantanu Deshpande, MD Pradeep Kumar Devan, MD Fernando Stucchi Devito, MD Anil Dhall, MD Gilvan Oliveira Dourado, MD Bipin Dubey, MD, DM Norberto Toazza Duda, MD Jaskaran S. Dugal, MD Shuvo Dutta, MD Timothy. C. Dy, MD Rajeev Edakutty, MD Satish Kumar Epari, MD Arunachalam Esakkiappan, MD Manoel Augusto Batista Esteves, MD Ali Faizal, MD Esmeralci Ferreira, MD Antonio Carlos Neves Ferreira, MD Hélio Roque Figueira, MD Augusto Lima Filho, MD Eulógio Emilio Martinez Filho, MD Heitor Maurício De Medeiros Filho, MD Moyses De Oliveira Lima Filho, MD Wilson Albino Pimentel Filho, MD Raul Ivo Rossi Filho, MD Newton Fernando Stadler De Souza Filho, MD José Breno De Sousa Filho, MD Louie Fischer, MD Alberto Gomes Taques Fonseca, MD Raimundo João Costa Furtado, MD Ramesh Gadepalli, MD Narayan Gadkar, MD Gamini Galapathy, MD Lazaro Claudovino Garcia, MD Naveen Garg, MD Gulab Chandra Gautam, MD Ulisses Marquez Gianecchini, MD Anand Gnanraj, MD Girish S. Godbole, MD Antonio Gilson Lapa Godinho, MD Nagendra Prasad Golla, MD Vitor Osorio Gomes, MD José Maria Pereira Gomes, MD T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Sreenivas Colanakuduru Gopal, MD Sridhara Gopalasastry, MD Aniyathodiyil Gopi, MD Carlos Antonio Mascia Gottschall, MD Raghu Thagachagere Rame Gowda, MD Jasprakash Singh Grewal, MD, DM Luiz Antonio Gubolino, MD Ênio Eduardo Guérios, MD Luiz Carlos Giuliano, MD Jorge Ilha Guimarães, MD Jose Silverio Peixoto Guimaraes, MD Heloisa Maria Melo Silva Guimarães, MD Surya Prakash Gulla, MD Amit Gupta, MD, DM Nishant Gupta, MD Pankaj Gupta, MD, DM Sanjiv Gupta, MD Shashi Bhushan Gupta, MD Suvir Gupta, MD Jorge Luis Haddad, MD Suhas Hardas, MD Sivadasan P. Harikrishnan, MD Jagdish Hiremath, MD Shirish Hiremath, MD Soon-Jun Hong, MD, PhD Young-Joon Hong, MD Biju C. Issaac, MD, DM Prashant Jagtap, MD Alkesh Jain, MD, DM Amit Jain, MD Bimit Kumar Jain, MD Nirmal Jain, MD, DM Sharad Jain, MD Satej Janorkar, MD R.K. Jaswal, MD Rakesh Kumar Jaswal, MD José Antonio Jatene, MD Dong-Woon Jeon, MD Paulo Henrique Jorge, MD George Joseph, MD George Johnson, MD Johny Joseph, MD Wilson Ambalathingal Joseph, BSC, MVS Hasit Joshi, MD Shishir Joshi, MD Kannan Jothiraj, MD João Orávio De Freitas Junior, MD Alcides Ferreira Junior, MD Pravin Rameshchandra Kahale, MD Luiz Junya Kajita, MD Annapoorna Kalia, MD Dhamodaran Kaliyamoorthy, MD Sanjay Kalkekar, MD Basavraj Chandrashekhar Kalmath, MD Chanakya Kishore Kumar Kammaripalli, MD G.R. Kane, MD Tae Soo Kang, MD, PhD Woong-Chol Kang, MD Nitin Kansal, MD Anuj Kapadia, MD Ketan Kapashi, MD Aditya Kapoor, MD Vipul Kapoor, MD Hashir Kareem, MD Rajeev Karnik, MD Chakkalakal Prahakaran Karunadas, MD Atul Kasliwal, MD Jamesthomas Kathalankal, MD B. Kesavamoorthy, MD Zakia Khan, MD Asit Khanna, MD Rajeev Khare, MD, DM Dong-Kie Kim, MD Hyong-Jun Kim, MD Joong Sun Kim, MD, PhD June-Hong Kim, MD Ki-Seok Kim, MD, PhD Pum-Jun Kim, MD, PhD Young-Hoon Kim, MD, PhD Yong-Giun Kim, Fellow K. S. Kishore, MD Tarlochan S. Kler, MD Subramanyam Kodangala, MD Young-Youp Koh, MD, PhD Prabhakar Chandrashekhar Koregol, MD Adrian Paulo Morales Kormann, MD Deepaesh Kothari, MD Deepak Krishnamurthy, MD Suresh Krishnan, MD Abhay Kumar, MD, DM Anand Kumar, MD Anil Kumar, MD, DM Ganesh Kumar, MD Krishnankutty Krishna Kumar, MD Manoj Kumar, MD Nanda Kumar, MD, DM Pampana Venkata Varaha Narasimha Markandeya Kumar, MD Prabhat Kumar, MD Prasana Kumar, MD, DM Pratap Kumar, MD Rakesh Kumar, MD Sampath Kumar, MD Sanjay Kumar, MD Vijay Kumar, MD Jabirabdullah Kutty, MD André Labrunie, MD Marta Moraes Labrunie, MD Tilak Kishor Lall, MD Ricardo Lasevitch, MD Kalidoss Latchumanadhas, MD Byoung-Kwon Lee, MD Jae-Beom Lee, MD Jae Hwan Lee, MD, PhD Jang Hoon Lee, MD Jong-Min Lee, MD, PhD Sang-Chil Lee, MD Seung Whan Lee, MD, PhD Seung-Uk Lee, MD Sang-Rok Lee, MD Suhas Lele, MD Viviana De Mello Guzzo Lemke, MD Valter Correia Lima, MD Antonio Augusto Guimaraes Lima, MD Marcelo Antônio Cartaxo Queiroga Lopes, MD João Batista Lopes Loures, MD Bruno Moulin Machado, MD Garikapat Mahesh, MD Samir Kanti Majumder, MD Chandrashekhar Makhale, MD C.N. Makhale, MD Susheel Kumar Malani, MD Ashish Kumar Malhotra, MD Hemant Malhotra, MD Vineet Malik, MD Ari Mandil, MD Luiz Alberto Rolla Maneschy, MD José Armando Mangione, MD Panchanatham Manokar, MD José Antonio Marin-Neto, MD Marcos Antonio Marino, MD Helman Campos Martins, MD Ganesh Mathan, MD Navin Mathew, MD The World’s Premier Interventional Experience TCT2011 Samuel Mathew, MD Nelson Durval Ferreira Gomes De Mattos, MD Luiz Alberto Piva E Mattos, MD Shafeeq Mattummal, MD, DM Alok Mazumdar, MD César Rocha Medeiros, MD Vivek Mehan, MD Haresh G. Mehta, MD George Cesar Ximenes Meirelles, MD Cintia Acosta Melo, MD Ajit Menon, MD Gaurav Minocha, MD Ricardo Pontes De Miranda, MD Anil Mishra, MD H.N. Mishra, MD Sundeep Mishra, MD Sunilkumar Modi, MD Bishav Mohan, MD Keon-Woong Moon, MD Raul D´aurea Mora Jr, MD Marco Antonio Gonçalves De Moura, MD Álvaro Vieira Moura, MD Siddharth Mukerjee, MD Ajit Mullasari, MD Antonio Jose Muniz, MD Viswanathan Muthukrishnan, MD Venkatesh Anegunta Naidu, MD Muralikrishna Nallamothu, MD Ganesan Nambirajan, MD Varun Shanker Narain, MD Patnaik Amar Narayan, MD Murugan Sankara Narayanan, MD Sajan Narayanan, MD Ranjit Kumar Nath, MD Girishb Navasundi, MD C.N. Nayak, MD Hernando Eduardo Nazzeta, MD Vijay Singh Negi, MD Deborah Christina Nercolini, MD Pedro Alves Lemos Neto, MD Milton De Macedo Soares Neto, MD Gilberto Lahorgue Nunes, MD Prasanna Nyayadhish, MD Adriano Dias Dourado Oliveira, MD Flavio Roberto Azevedo De Oliveira, MD Itamar Ribeiro De Oliveira, MD Ludmilla Almeida Da Rocha Ribeiro De Oliveira, MD Paulo Sérgio De Oliveira, MD Abraham Oomman, MD Costantino Costantini Ortiz, MD Evandro Cesar Vidal Osterne, MD Shoaib Padaria, MD Sreekala Padmanabhan, MD José Nogueira Paes Jr, MD Devkishen Pahlajani, MD Mariappan Palanisamy, MD Girish Meennahalli Palleda, MD Naresh Pamnani, MD A.K. Pandey, MD Rashmit Pandya, MD Manotosh Panja, MD Yongwhi Par, MD, PhD Gurunath Parale, MD Jagdish Parikh, MD Prakashvir Parikh, MD Hun-Jun Park, MD Jong-Pil Park, MD Jong-Seon Park, MD Kyoung Woo Park, MD, PhD Yong-Whi Park, MD Woo Jung Park, MD, PhD Rajiv Passey, MD Balagopalan Jayagopal Pathiyil, MD Rajendra Patil, MD, DM Rahul Patil, MD Nitin Suresh Patki, MD João Eduardo Tinoco De Paula, MD Carlos Augusto Cardoso Pedra, MD Mukund Penurkar, MD Luis Amandio Coelho Pereira, MD Marco Aurélio Magalhães Pereira, MD Govinda Madhavan Pillai, MD Jayakumar Balakrishna Pillai, MD Ramakrishna Pillai , MD, DM Brian Pinto, MD Pawan Poddar, MD Antenor Lages Fortes Portela, MD Sanjay Porwal, MD Anil Potdar, MD Jayesh Prajapati, MD Sergio Correa Prata, MD Rajenakumar Premchand, MD Mauricio Lopes Prudente, MD C.S. Pruthi, MD Aniket Puri, MD Raman Puri, MD Alexandre Schaan De Quadros, MD Francisco Jose Araujo Chamié Queiroz, MD Bagirath Raghuraman, MD Asif Raheem, MD Abdul Kasem Mohammad Fazlur Rahman, MD Afzalur Rahman, MD Mahbubor Rahman, MD Siddiqur Rahman, MD Thachathodiyil Rajesh, MD Pusapativenkataramachana Raju, MD Rangaraj Ramalingam, MD Vaidyanathan Peruvamba Raman, MD Gian C. Rana, MD Alok Ranjan, MD Anand Rao, MD M. Srinivas Rao, MD Pratapchana Rath, MD Rajiv Rathi, MD Sivakumar Rathinavel, MD Dilip Kumar Ratnani, MD Pachakkoottathil Raveendran, MD, DM Gupta Ravi, MD Khandenahally Palya S. Ravindranath, MD Anilkrishna Reddy, MD Mandala Gokul Reddy, MD Sujay Renga, MD, DM Jorge Pinto Ribeiro, MD Henrique Barbosa Ribeiro, MD Cyro Vargues Rodrigues, MD Kanchan Satish Roplekar, MD Satish Murlidharrao Roplekar, MD Sanjeeb Roy, MD Subhanan Roy, MD Sunil Baran Roy, MD Jamil Abdalla Saad, MD Arabinda Saha, MD Uttam Kumar Saha, MD Atul Kumar Sahi, MD P.K. Sahoo, MD Ashutosh Sahu, MD Sanjib Kumar Sahu, MD Goyal Saket, MD Anil Saleem, MD, DM José Ary Boechat E Salles, MD Décio Salvadori Jr, MD Mahenaprasad Samal, MD Amit Sambare, MD Fernando Mendes Sant´anna, MD Harikrishnan Madhavankutty Santhakumari, MD Marcelo De Freitas Santos, MD Prakash Sanzgiri, MD Vikas Sardana, MD Pramod Ratanchand Sarnot, MBBS, DHE, MD Toutem Sashikant, MD Shireesh Sathe, MD Antônio Luiz Secches, MD Durgaprasadraja Sekhar, MD Fabio Augusto Selig, MD Rajiv Sethi, MD Bhadresh, Shah, MD, DM Bhaskar Shah, MD Bhupesh Shah, MD Chetan Shah, MD Dhiren Shah, MD, DM Hetan Shah, MD Hitesh. J. Shah, MD Jay Manojkumar Shah, MD Prasad Shah, MD O.M. Shankar, MD Anil Sharma, MD Arvind Sharma, MD Kamal Sharma, MD Manish Sharma, MD, DM Mridul Sharma, MD, DM Mridul Sharma, MD Sunil Kumar Sharma, MD, DM Anand Ramesh Shenoy, MD Chirag Sheth, MD G.G. Shetty, MD Prabhakar Shetty, MD Ranjan Shetty, MD Sadanand Shetty, MD Sreekanth Shetty, MD Eun Seok Shin, MD, PhD Deepak Jijabrao Shinde, MBBS, DnB Bharat Shivdasani, MD Jalepalli Shivkumar Rao, MD Célia Maria Camelo Silva, MD Eduardo Missel Silva, MD Ricardo Cavalcante E Silva, MD Samuel Silva Da Silva, MD Stefan Costa Siveira, MD Alok Kumar Singh, MD Parminder Singh, MD Rakesh Kumar Singh, MD Nakul Sinha, MD Ramanand Sinha, MD Sudhir Chandra Sinha, MD Dimytri Alexandre De Alvim Siqueira, MD Paulo Rogério Soares, MD Vinod Somani, MD Antonio Cesar De Souza, MD Antonio José Neri Souza, MD Rodolfo Staico, MD Mantravadi Sai Sudhakar, MD, DM Jon Suh, MD, PhD Pawan Suri, MD, DM Satish Suryavanshi, MD Puttam Reddy Susheel, MD Chetan Swaroop, MD Ajit Tambolkar, MD Luiz Fernando Leite Tanajura, MD Sergio Gustavo Tarbine, MD Sunil Thanvi, MD Luiz Eduardo Koenig Sao Thiago, MD Manikandan Thiruvanath Variam, MD Vinod Thomas, MD, DM, DnB James Thomas, MD T r a n s c at h e t e r Cardiovascular Therapeutics Joby Kochuparambil Thomas, MD Pyarelal Tiwari, MD, MRCP Nityanand Tripathi, MD Rutvik Trivedi, MD Sunil Trivedi, MD Rogério Tadeu Tumelero, MD Mir Jamal Uddin, MD D. Vaidiyanathan, MD Ali Faizal Valiyakath, MD Kesava Vallabhapurapu, MD Kiran Varghese, MD Jagmohan Varma, MD Manu Varma, MD Vinicius Daher Vaz, MD Manjunatha Bagur Venkataramaiah, MD Krishnan Nair Venugopal, MD, DM Puneet Kumar Verma, MD Suresh Vijan, MD Vinod Vijan, MD Maniyal Vijayakumar, MD Rajesh Vijayvergia, MD Marco Vugman Wainstein, MD Gagandeep Singh Wander, MD R.D. Yadave, MD Joo-Young Yang, MD, PhD Shiva Kumar Yerra, MD Sang-Yeob Yim, MD Jung-Han Yoon, MD, PhD Cheol-Woong Yu, MD Alexandre Do Canto Zago, MD Alcides José Zago, MD www . t c t c o n f e r e n c e . c o m 31 United States Faculty J. Dawn Abbott, MD Rhode Island Hospital Providence, RI Husam H. Balkhy, MD The Wisconsin Heart Hospital West Allis, WI William E. Boden, MD Buffalo General Hospital Buffalo, NY Mark W. Burket, MD University of Toledo Medical Center Toledo, OH Alex Abou-Chebl, MD University of Louisville Stroke Center Louisville, KY Stephen Balter, PhD Cardiovascular Research Foundation New York, NY Steven F. Bolling, MD University of Michigan Ann Arbor, MI Daniel Burkhoff, MD, PhD CircuLite Saddle Brook, NJ William T. Abraham, MD Ohio State University Columbus, OH Subhash Banerjee, MD UT Southwestern Clinical Heart Center Dallas, TX Johannes Bonatti, MD University of Maryland Baltimore, MD David H. Adams, MD Mount Sinai Medical Center New York, NY Sripal Bangalore, MD, MHA New York University School of Medicine New York, NY Robert O. Bonow, MD Northwestern University Chicago, IL Louis A. Cannon, MD Northern Michigan Hospital Heart and Vascular Institute, Petoskey Cardiology Petoskey, MI Tayo A. Addo, MD UT Southwestern Clinical Heart Center Dallas, TX Kenneth W. Baran, MD United Heart and Vascular Clinic Saint Paul, MN Brett E. Bouma, PhD Massachusetts General Hospital Boston, MA Heather L. Agler, PhD US Food and Drug Administration Silver Spring, MD Ravit Barkama, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Bruce Bowers, MD Dallas Cardiovascular Specialists Dallas, TX Jodi Akin, VP Edwards Lifesciences Irvine, CA Steven L. Almany, MD William Beaumont Hospital Boomfield Hills, MI Caesar Alvero, AAS, RCIS NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY John A. Ambrose, MD UCSF Fresno Fresno, CA Zahid Amin, MBBS, MD Rush University Medical Center Chicago, IL Dominick J. Angiolillo, MD, PhD University of Florida-Shands Jacksonville, FL Brian H. Annex, MD University of Virginia Charlottesville, VA Gary M. Ansel, MD Riverside Methodist Hospital Columbus, OH Robert J. Applegate, MD Wake Forest University School of Medicine Winston-Salem, NC Salman A. Arain, MD Tulane University School of Medicine New Orleans, LA Michael Argenziano, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Herbert D. Aronow, MD, MPH St. Joseph Mercy Hospital Ypsilanti, MI Vasilis Babaliaros, MD Emory University School of Medicine Atlanta, GA J. Michael Bacharach, MD, MPH North Central Heart Institute Sioux Falls, SD Steven R. Bailey, MD University of Texas Health Science Center at San Antonio San Antonio, TX 32 program · Colin M. Barker, MD Hermann Memorial Heart and Vascular Institute Houston, TX Theodore A. Bass, MD University of Florida Health Science Center Jacksonville, FL Eric R. Bates, MD University of Michigan Medical Center Ann Arbor, MI Mark C. Bates, MD CAMC Vascular Center of Excellence Charleston, WV Joseph E. Bavaria, MD University of Pennsylvania Philadelphia, PA Anthony A. Bavry, MD, MPH University of Florida Gainesville, FL Nirat Beohar, MD Columbia University Division of Cardiology at Mount Sinai Medical Center Miami, FL Daniel S. Berman, MD Cedars-Sinai Medical Center Los Angeles, CA Robert M. Bersin, MD Seattle Cardiology Seattle, WA Andrew J. Boyle, MD, PhD UCSF Medical Center San Francisco, CA Russell A. Brandwein, RPA-C NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Somjot S. Brar, MD Kaiser Permanente Los Angeles, CA Sorin J. Brener, MD New York Methodist Hospital Brooklyn, NY Andreas Brieke, MD University of Denver Aurora, CO Emmanouil S. Brilakis, MD, PhD VA North Texas Health Care System and UT Southwestern Medical Center Dallas, TX Ralph G. Brindis, MD, MPH Northern California Kaiser Permanente Oakland, CA Todd J. Brinton, MD Stanford University Medical Center Stanford, CA Bruce R. Brodie, MD Moses Cone Heart and Vascular Center Greensboro, NC Thomas G. Brott, MD Mayo Clinic Jacksonville, FL Ronald Caputo, MD SJH Cardiology Associates Liverpool, NY Blase A. Carabello, MD Veterans Affairs Medical Center Houston, TX John D. Carroll, MD University of Colorado Denver Aurora, CO Joseph P. Carrozza Jr, MD Caritas St. Elizabeth’s Medical Center Boston, MA Charles E. Chambers, MD Hershey Medical Center Hershey, PA Paul S. Chan, MD Saint Luke’s Mid America Heart and Vascular Institute Kansas City, MO S. James Chen, PhD University of Colorado Hospital Aurora, CO James H. Chesebro, MD UMass Memorial Medical Center Worcester, MA W. Randolph Chitwood Jr, MD East Carolina University School of Medicine Greenville, NC Leslie Cho, MD Cleveland Clinic Cleveland, OH Lorraine Choi, MD UTMB Galveston, TX Karen Christman, PhD University of California San Diego La Jolla, CA Maurice Buchbinder, MD Foundation for Cardiovascular Medicine San Diego, CA Nicolas A.F. Chronos, MD Saint Joseph’s Translational Research Institute/American Cardiovascular Research Institute Atlanta, GA Michael Buck Abbott Vascular Abbott Park, IL Timothy A.M. Chuter, DM UCSF Medical Center San Francisco, CA John A. Bittl, MD Munroe Regional Medical Center Ocala, FL Clifford J. Buckley, MD Scott & White Clinic Temple, TX Daniel G. Clair, MD Cleveland Clinic Foundation Cleveland, OH Peter C. Block, MD Emory University Hospital Atlanta, GA James P. Burke, MD, PhD Lehigh Valley Health Network Allentown, PA Sarah Clarke, MSN, NP Scripps Clinic and Research Foundation La Jolla, CA Ashley B. Boam, MSBE US Food and Drug Administration Silver Spring, MD M. Nicholas Burke, MD Minneapolis Heart Institute Foundation Minneapolis, MN Joseph C. Cleveland, MD University of Colorado Anschutz Medical Center Aurora, CO Patricia J. Best, MD Mayo Clinic Rochester, MN Deepak L. Bhatt, MD, MPH VA Boston Healthcare System and Brigham and Women’s Hospital Boston, MA T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 David J. Cohen, MD Saint Luke’s Mid-America Heart Institute Kansas City, MO George D. Dangas, MD, PhD Mount Sinai Medical Center New York, NY Mauricio G. Cohen, MD University of Miami Hospital Miami, FL Tony Das, MD Presbyterian Heart Institute-Dallas Dallas, TX William E. Cohn, MD Texas Heart Institute at St. Luke’s Episcopal Hospital Houston, TX Rajesh M. Dave, MD Central Pennsylvania Cardiovascular Research Institute Harrisburg, PA Gerald D. Dorros, MD, ScD Dorros-Feuer Interventional Cardiovascular Disease Foundation, Ltd. Wilson, WY Michael B. Collins, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Charles J. Davidson, MD Northwestern Memorial Hospital Chicago, IL John S. Douglas Jr, MD Emory University School of Medicine Atlanta, GA Michael J. Davidson, MD Brigham and Women’s Hospital Boston, MA Robert D. Dowling, MD University of Louisville School of Medicine Louisville, KY Tyrone J. Collins, MD Ochsner Clinic Foundation New Orleans, LA Anthony J. Comerota, MD Jobst Vascular Institute Toledo, OH Mark W. Connolly, MD St. Joseph’s Hospital Medical Center Paterson, NJ Christopher J. Cooper, MD University of Toledo Medical Center Toledo, OH Jeff Davis, RRT, RCIS Edison State University Fort Myers, FL Keith D. Dawkins, MD Boston Scientific Natick, MA Anthony Dawson, MSN, RN NewYork-Presbyterian Hospital New York, NY Pilar Dolcimascolo, RPA-C NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Ted Feldman, MD Evanston Hospital Evanston, IL Valerian Fernandes, MD Medical University of South Carolina Charleston, SC Dennis J Donohoe, MD Durham, NC Elazer R. Edelman, MD, PhD Brigham and Women’s Hospital Cambridge, MA Neal L. Eigler, MD St. Jude Medical Sylmar, CA Stephen G. Ellis, MD Cleveland Clinic Foundation Cleveland, OH Gregory P. Fontana, MD Cedars-Sinai Medical Center Los Angeles, CA Prakash Deedwania, MD UCSF Medical Center Fresno, CA Stephen E. Epstein, MD Washington Hospital Center Washington, DC Marco A. Costa, MD, PhD University Hospitals Case Medical Center Cleveland, OH Regina Deible, BSN, RN Suburban Hospital/ Johns Hopkins Medicine Bethesda, MD Michael D. Ezekowitz, MB, ChB, DPhil Lankenau Medical Center Wynnewood, PA Michael J. Cowley, MD Medical College of Virginia Richmond, VA David A. Cox, MD Lehigh Valley Hospital Bethlehem, PA Michael H. Crawford, MD University of California, San Francisco Medical Center San Francisco, CA Enrique Criado, MD University of Michigan Health System Ann Arbor, MI Frank J. Criado, MD Union Memorial Hospital/MedStar Health Baltimore, MD Donald Cutlip, MD Beth Israel Deaconess Medical Center Boston, MA Michael D. Dake, MD Stanford University School of Medicine Stanford, CA Kate Dalton, MS, RD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Tony J. DeMartini, MD Prairie Cardiovascular Springfield, IL Ali E. Denktas, MD University of Texas at Houston Houston, TX Joseph J. DeRose, MD Albert Einstein College of Medicine Montefiore Medical Group Bronx, NY Tim A. Fischell, MD Heart Institute at Borgess Medical Center Kalamazoo, MI Thomas J. Fogarty, MD Fogarty Institute for Innovation Mountain View, CA Nicola Corvaja, MD Stamford Hospital Stamford, CT Todd D. Courtney US Food and Drug Administration Silver Spring, MD Aloke V. Finn, MD Emory Crawford Long Hospital Atlanta, GA John Flack, MD, MPH Wayne State University Detroit, MI Chad Cornell Medtronic, Inc. Minneapolis, MN Anthony N. DeMaria, MD University of California, San Diego School of Medicine San Diego, CA Michael A. Fifer, MD Massachusetts General Hospital Boston, MA Peter J. Fitzgerald, MD, PhD Stanford University Medical Center Stanford, CA Larry S. Dean, MD University of Washington Regional Heart Center Seattle, WA Maria Rosa Costanzo, MD Midwest Heart Specialists Naperville, IL T r a n s c at h e t e r Cardiovascular Therapeutics Sammy Elmariah, MD, MPH Massachusetts General Hospital Boston, MA Robert J. Freedman Jr, MD Life Recovery Systems Alexandria, LA Peter S. Fail, MD Cardiovascular Institute of the South Houma, LA William J. French, MD Harbor - UCLA Medical Center Torrance, CA Glenna Friedman, RN NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Valentin Fuster, MD, PhD Mount Sinai Medical Center New York, NY Andrew Farb, MD US Food & Drug Administration Silver Spring, MD James S. Gammie, MD University of Maryland Heart Center Baltimore, MD Michael E. Farkouh, MD, MSc Mount Sinai School of Medicine New York, NY Lawrence A. Garcia, MD St. Elizabeth’s Medical Center Boston, MA David P. Faxon, MD Brigham and Women’s Hospital Boston, MA Neal Fearnot, PhD Cook Group Incorporated W. Lafayette, IN Timothy J. Gardner, MD Center for Heart and Vascular Health, Christiana Care Health System Newark, DE Todd M. Dewey, MD Medical City Dallas Dallas, TX William F. Fearon, MD Stanford University Medical Center Stanford, CA Kirk N. Garratt, MD, MSc Lenox Hill Hospital New York, NY Nabil Dib, MD, MSc Chandler Regional and Mercy Gilbert Medical Centers/Catholic Healthcare West Gilbert, AZ Frederick Feit, MD New York University Medical Center New York, NY Philippe Genereux, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Simon R. Dixon, MBChB William Beaumont Hospital Royal Oak, MI Ozgen Dogan, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY David S. Feldman, MD, PhD Abbott Northwestern/Minneapolis Heart Institute Minneapolis, MN Isaac George, MD NewYork-Presbyterian Hospital New York, NY Dmitriy N. Feldman, MD NewYork-Presbyterian Cornell Hospital New York, NY Jon C. George, MD Deborah Heart and Lung Center Browns Mills, NJ Marc D. Feldman, MD University of Texas Health Science Center at San Antonio San Antonio, TX Bernard J. Gersh, MB, ChB, DPhil Mayo Clinic Rochester, MN www . t c t c o n f e r e n c e . c o m 33 United States Faculty Gary Gershony, MD John Muir Cardiovascular Institute Piedmont, CA Cindy L. Grines, MD Detroit Medical Center Royal Oak, MI Ziyad M. Hijazi, MD, MPH Rush University Medical Center Chicago, IL David B. Jessup, MD St. Joseph Hospital Bellingham, WA C. Michael Gibson, MD Beth Israel Deaconess Medical Center Boston, MA Eugene A. Grossi, MD NYU Medical Center New York, NY Mark Andrew Hlatky, MD Stanford University School of Medicine Stanford, CA Thomas K. Jones, MD Seattle Children’s Hospital Seattle, WA Ian C. Gilchrist, MD Penn State/Hershey Medical Center Hershey, PA Luis Gruberg, MD Stony Brook University Medical Center Stony Brook, NY Judith S. Hochman, MD New York University Medical Center New York, NY Ulrich P. Jorde, MD NewYork-Presbyterian Hospital New York, NY Linda D. Gillam, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Michael Guiry, MBA, RPA-C NewYork-Presbyterian Hospital New York, NY John McB. Hodgson, MD Geisinger Health System Wilkes Barre, PA James D. Joye, DO El Camino Hospital Mountain View, CA Paul A. Gurbel, MD Sinai Hospital of Baltimore System Baltimore, MD Udo Hoffmann, MD, MPH Massachusetts General Hospital Boston, MA Hitinder S. Gurm, MD University of Michigan Medical Center Ann Arbor, MI Lawrence Hofmann, MD Stanford School of Medicine Stanford, CA Rona G. Kahn, DS NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Swaminatha V. Gurudevan, MD Cedars-Sinai Medical Center Los Angeles, CA David R. Holmes Jr, MD Mayo Clinic Rochester, MN Lee R. Guterman, MD, PhD Catholic Health System of Buffalo Amherst, NY Howard M. Holstein, JD Department of Health, Education, and Welfare Washington, DC A. Marc Gillinov, MD Cleveland Clinic Foundation Cleveland, OH Gregory R. Giugliano, MD, SM Baystate Medical Education and Research Foundation Springfield, MA Peter J. Goadsby, MD, PhD UCSF Medical Center San Francisco, CA Sheldon Goldberg, MD Cardiology Consultants of Philadelphia Philadelphia, PA Steven L. Goldberg, MD University of Washington Seattle, WA Mark Goldberger, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Lee Goldman, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY James A. Goldstein, MD William Beaumont Hospital Royal Oak, MI Juan F. Granada, MD The Jack H. Skirball Center for Cardiovascular Research Orangeburg, NY Luis A. Guzman, MD University of Florida Jacksonville, FL Rebecca Tung Hahn, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Adam Hansgen, BS University of Colorado Health Sciences Center Aurora, CO Joshua M. Hare, MD Miller School of Medicine Miami, FL Kishore J. Harjai, MD Guthrie Clinic Sayre, PA Christopher B. Granger, MD Duke University Medical Center Durham, NC William T. Harrington, MD, MBA Three Arch Partners Portola Valley, CA J. Aaron Grantham, MD University of Missouri Kansas City and Mid America Heart Institute Kansas City, MO Marian C. Hawkey, RN NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY William A. Gray, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Timothy D. Henry, MD Minneapolis Heart Institute Foundation Minneapolis, MN Ralf J. Holzer, MD, MSc Nationwide Children’s Hospital Columbus, OH W. Craig Hooper, PhD Centers for Disease Control and Prevention Atlanta, GA L. Nelson Hopkins, MD Millard Fillmore Gates Hospital Buffalo, NY Phillip A. Horwitz, MD University of Iowa Hospitals & Clinics Iowa City, IA Syed Hossainy, PhD Abbott Vascular Santa Clara, CA Fumiaki Ikeno, MD Stanford University Medical Center Palo Alto, CA Frank F. Ing, MD Texas Children’s Hospital Houston, TX Alice K. Jacobs, MD Boston University Medical Center Boston, MA Michael R. Jaff, DO Massachusetts General Hospital Boston, MA Ross A. Jaffe, MD Versant Ventures Menlo Park, CA Paul A. Grayburn, MD Baylor University Medical Center Dallas, TX James B. Hermiller Jr, MD St. Vincent Hospital/ The Heart Center of Indiana Indianapolis, IN Philip Green, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Howard C. Herrmann, MD University of Pennsylvania Philadelphia, PA Robert D.B. Jaquiss, MD Duke University Durham, NC Richard R. Heuser, MD St. Luke’s Medical Center Phoenix, AZ Allen Jeremias, MD, MSc Stony Brook University Medical Center Stony Brook, NY Ann Greenberg, MSN Suburban Hospital Bethesda, MD 34 Robert A. Guyton, MD Emory University Hospital Atlanta, GA program · Jo Carol Hiatt, MD Kaiser Permanente Pasadena, CA T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Farouc Jaffer, MD, PhD Massachusetts General Hospital Boston, MA Greg L. Kaluza, MD, PhD The Jack H. Skirball Center for Cardiovascular Research Orangeburg, NY David E. Kandzari, MD Piedmont Heart Institute Atlanta, GA Samir R. Kapadia, MD Cleveland Clinic Foundation Cleveland, OH Aaron V. Kaplan, MD Dartmouth-Hitchcock Medical Center Lebanon, NH Navin K. Kapur, MD Tufts Medical Center Boston, MA Saibal Kar, MD Cedars-Sinai Medical Center Los Angeles, CA John W. Karanian, PhD US Food and Drug Administration Laurel, MD Dimitri Karmpaliotis, MD Piedmont Heart Institute Atlanta, GA Barry T. Katzen, MD Baptist Cardiac and Vascular Institute Miami, FL Sanjay Kaul, MD Cedars-Sinai Medical Center Los Angeles, CA Clifford J. Kavinsky, MD, PhD Rush University Medical Center Chicago, IL Martina Kelly Speight, RN, BSN Stanford University Medical Center Stanford, CA Dean J. Kereiakes, MD The Christ Hospital Cincinnati, OH Morton J. Kern, MD University of California Irvine Orange, CA Akshay Khandelwal, MD Henry Ford Hospital Northville, MI R. Stefan Kiesz, MD San Antonio Endovascular and Heart Institute San Antonio, TX The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Michael S. Kim, MD University of Washington Medical Center Seattle, WA Tak W. Kwan, MD Beth Israel Medical Center New York, NY Glenn N. Levine, MD Baylor College of Medicine Houston, TX Tift Mann, MD Wake Heart Associates Raleigh, NC Carey D. Kimmelstiel, MD Tufts Medical Center Boston, MA Elena Ladich, MD CVPath Institute, Inc. Gaithersburg, MD John C. Lewin, MD American College of Cardiology Washington, DC Steven V. Manoukian, MD Sarah Cannon Research Institute Nashville, TN Nicholas N. Kipshidze, MD, PhD Lenox Hill Hospital New York, NY Roger J. Laham, MD Beth Israel Deaconess Medical Center Boston, MA Michael J. Lim, MD Saint Louis University Saint Louis, MO Gopi Manthripragada, MD University of California Los Angeles, CA Ajay J. Kirtane, MD, SM NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY John R. Laird Jr, MD UC Davis Medical Center Sacramento, CA Scott Lim, MD UVA Medical Center Charlottesville, VA James R. Margolis, MD Jackson South Community Hospital Miami, FL Gervasio A. Lamas, MD Mount Sinai Medical Center Miami Beach, FL JoAnn Lindenfeld, MD University of Colorado Health Sciences Center Aurora, CO Jonathan D. Marmur, MD Downstate Medical Center Brooklyn, NY Jacqueline Kixmiller, RN Stanford University Medical Center Stanford, CA Neal S. Kleiman, MD Methodist DeBakey Heart and Vascular Center Houston, TX Robert A. Kloner, MD, PhD Good Samaritan Hospital Los Angeles, CA Susheel Kodali, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Raghu Kolluri, MD Prairie Vascular Institute Springfield, IL David F. Kong, MD, AM, DMT Duke University Medical Center Durham, NC Zvonimir Krajcer, MD St. Luke’s Episcopal Hospital Houston, TX Paul H. Kramer, MD Liberty Cardiovascular Specialists Liberty, MO Edward M. Kreps, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Alexandra J. Lansky, MD Yale School of Medicine New Haven, CT Tim J. Lapp, RCIS Lancaster General Hospital Lancaster, PA Kevin Larkin TherOx Irvine, CA John M. Lasala, MD, PhD Washington University School of Medicine St. Louis, MO Pedro Martinez-Clark, MD Jupiter Medical Center Miami, FL Laura Mauri, MD, MSc Brigham and Women’s Hospital Boston, MA Byron K. Lee, MD UCSF Medical Center San Francisco, CA Kapildeo Lotun, MD Virginia Commonwealth University Medical Center Richmond, VA James B. McClurken, MD Temple Cardiothoracic Surgery Associates Philadelphia, PA Michael S. Lee, MD UCLA Medical Center Los Angeles, CA Reginald I. Low, MD UC Davis Heart Center Sacramento, CA Randall J. Lee, MD, PHD University of California, San Francisco San Francisco, CA Alan Lumsden, MD Methodist DeBakey Heart and Vascular Center Houston, TX Massoud A. Leesar, MD University of Cincinnati Cincinnati, OH Aaron D. Kugelmass, MD Baystate Medical Center Springfield, MA Martin B. Leon, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Robert Kutys, MS, PA(ASCP) CVPath Institute, Inc. Gaithersburg, MD William L. Lombardi, MD North Cascade Cardiology Bellingham, WA Tim I. Martin, RCIS Lancaster General Hospital Lancaster, PA Robert A. Lookstein, MD Mount Sinai Medical Center New York, NY Robert J. Lederman, MD National Heart, Lung, and Blood Institute Bethesda, MD Mitchell W. Krucoff, MD Duke University Medical Center Durham, NC Michael A. Kutcher, MD Wake Forest University Baptist Medical Center Winston-Salem, NC Julie Logan, RN Foundation for Cardiovascular Medicine San Diego, CA Jon S. Matsumura, MD University of Wisconsin Madison, WI W. Anthony Lee, MD Lynn Heart and Vascular Institute Boca Raton, FL Frederick Kushner, MD Heart Clinic of Lousiana Marrero, LA Jack L. Martin, MD Methodist Hospitals, San Antonio Texas Live Oak, TX Frank Litvack, MD Cedars-Sinai Medical Center Los Angeles, CA Kareen Looi Campbell, CA Paul A. LaViolette SV Life Sciences Boston, MA Prakash Krishnan, MD Mount Sinai Medical Center New York, NY Chad Kugler BridgePoint Medical Plymouth, MN David J. Maron, MD Vanderbilt Chest Pain Center Nashville, TN Richard J. Linder Coherex Medical, Inc. Salt Lake City, UT Doff B. McElhinney, MD Children’s Hospital Boston Boston, MA James F. McKinsey, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Michael J. Mack, MD The Heart Hospital Baylor Plano Plano, TX Akiko Maehara, MD Cardiovascular Research Foundation New York, NY Brij Maini, MD Pinnacle Health System Harrisburg, PA Jane A. Leopold, MD Brigham and Women’s Hospital Boston, MA William H. Maisel, MD, MPH US Food and Drug Administration Silver Spring, MD Norman E. Lepor, MD Cedars-Sinai Medical Center Beverly Hills, CA Raj Makkar, MD Cedars-Sinai Medical Center Los Angeles, CA Stamatios Lerakis, MD Emory Healthcare Atlanta, GA Joshua Makower, MD Stanford University Stanford, CA Amir Lerman, MD Mayo Clinic Rochester, MN Thomas H. Maloney, MHA, RCIS Memorial Regional Medical Center Mechanicsville, VA Daniel J. McCormick, DO Hahnemann University Hospital Philadelphia, PA Thomas O. McNamara, MD UCLA Medical Center Los Angeles, CA Edward J. McNulty, MD Kaiser San Francisco San Francisco, CA John A. McPherson, MD Vanderbilt University Nashville, TN Roxana Mehran, MD Mount Sinai Medical Center New York, NY Davendra Mehta, MD Mount Sinai Medical Center New York, NY Manish Mehta, MD Albany Medical Center Albany, NY www . t c t c o n f e r e n c e . c o m 35 United States Faculty Sameer Mehta, MD Columbia Cedars Medical Center Miami, FL Sandeep Nathan, MD, MSc University of Chicago Medical Center Chicago, IL D. Christopher Metzger, MD Wellmont CVA Heart Institute Kingsport, TN Manuela Negoita, MD Medtronic Santa Rosa, CA Philip M. Meyers, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Christopher M. Nelson, RN, RCIS Sentara College of Health Sciences Chesapeake, VA Andrew D. Michaels, MD, MAS St. Joseph Hospital Eureka, CA Robert E. Michler, MD Montefiore Einstein Center New York, NY Hilary Nierenberg, NP, MPH NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY D. Craig Miller, MD Stanford University Medical School Stanford, CA James K. Min, MD NewYork-Presbyterian Hospital/ Weill Cornell Medical College New York, NY David Paniagua, MD St. Luke’s Episcopal Hospital/ Texas Heart Institute Houston, TX Manish A. Parikh, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Duane S. Pinto, MD, MPH Beth Israel Deaconess Medical Center Boston, MA Hina M. Pinto, MSE US Food and Drug Administration Silver Spring, MD Dan Polcyn Business Development Cardiovascular Service Line Palo Alto, CA Vincent J. Pompili, MD Ohio State University Medical Center Columbus, OH Sahil A. Parikh, MD University Hospitals Case Medical Center Cleveland, OH Jeffrey J. Popma, MD Beth Israel Deaconess Medical Center Boston, MA Alexander Nikanorov, MD, PhD Abbott Vascular Santa Clara, CA Helen Parise, ScD Cardiovascular Research Foundation New York, NY Thomas A. Ports, MD University of California SF San Francisco, CA Serjan D. Nikolic CardioKinetix, Inc. Menlo Park, CA Juan C. Parodi, MD University of Miami Pinecrest, FL Robert S. Poston, MD UA Sarver Heart Center Tucson, AZ Michelle O’Donoghue, MD, MPH Brigham and Women’s Hospital Boston, MA Amit Patel, MD, MS University of Utah Salt Lake City, UT Thomas J. Povsic, MD, PhD Duke University Medical Center Chapel Hill, NC Patrick T. O’Gara, MD Brigham and Women’s Hospital Boston, MA Manesh R. Patel, MD Duke University Medical Center Durham, NC Alex Powell, MD Baptist Cardiac and Vascular Institute Miami, FL E. Magnus Ohman, MD Duke University Medical Center Durham, NC Rahul S. Patel, MD University of Maryland Medical Center Baltimore, MD Abhiram Prasad, MD Mayo Clinic Rochester, MN Semih Oktay, PhD CardioMed Device Consultants Baltimore, MD Vinod Patel, MD Mount Sinai Medical Center New York, NY Matthew J. Price, MD Scripps Clinic La Jolla, CA Jeffrey W. Olin, DO Mount Sinai School of Medicine New York, NY Raghotham R. Patlola, MD Cardiovascular Institute of the South Lafayette, LA William W. O’Neill, MD University of Miami Miami, FL Bray Patrick-Lake PFO Research Foundation Boulder, CO Lauren T. Privitera, MPH Columbia University Medical Center, Health Policy and Management New York, NY Fumiyuki Otsuka, MD CVPath Institute, Inc. Gaithersburg, MD Wesley R. Pedersen, MD Minneapolis Heart Institute Foundation Minneapolis, MN Mauro Moscucci, MD University of Miami Miami, FL Kenneth Ouriel, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Lynn Peng, MD Stanford University Medical Center Stanford, CA Jeffrey W. Moses, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Christopher D. Owens, MD University of California, San Francisco Medical Center San Francisco, CA Issam D. Moussa, MD Mayo Clinic, Jacksonville Jacksonville, FL Francis D. Pagani, MD, PhD University of Michigan Ann Arbor, MI James E. Muller, MD InfraReDx Burlington, MA Igor F. Palacios, MD Massachusetts General Hospital Boston, MA Michael A. Mussallem Edwards Lifesciences Irvine, CA James M. Palazzo, MBA Paragon Health Southlake, TX Srihari S. Naidu, MD Winthrop University Hospital Mineola, NY Julio C. Palmaz, MD University of Texas Health Science Center at San Antonio San Antonio, TX Gary S. Mintz, MD Cardiovascular Research Foundation Washington, DC Greg Mishkel, MD Prairie Cardiovascular Consultants Springfield, IL David J. Moliterno, MD University of Kentucky Lexington, KY Frederic H. Moll, MD Hansen Medical Mountain View, CA Michael Mooney, MD Minneapolis Heart Institute Foundation Minneapolis, MN Pedro R. Moreno, MD Mount Sinai Medical Center New York, NY Nancy Morris, RN, MSN Interventional Technologies San Diego, CA Masataka Nakano, MD CVPath Institute, Inc Gaithersburg, MD 36 Christopher D. Nielsen, MD Medical University of South Carolina Charleston, SC Samir B. Pancholy, MD Wright Center for Graduate Medical Education and the Commonwealth Medical College Clarks Summit, PA program · Marc S. Penn, MD, PhD Summa Health System Cleveland, OH Emerson C. Perin, MD, PhD Texas Heart Institute Houston, TX Alice A. Perlowski, MD NorthShore University HealthSystem Evanston, CA John L. Petersen, MD Swedish Medical Center Seattle, WA Harry R. Phillips, MD Duke University Medical Center Durham, NC Augusto D. Pichard, MD Washington Hospital Center Washington, DC Ileana L. Piña, MD, MPH Albert Einstein College of Medicine Bronx, NY T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s John D. Puskas, MD, MSc Emory University Hospital Midtown Atlanta, GA Patricia M. Pye, RN, MS Carolinas Medical Center Charlotte, NC Robert T. Pyo, MD Mount Sinai Medical Center New York, NY Michael Querijero, RPA-C NewYork-Presbyterian Hospital New York, NY Ramon Quesada, MD Baptist Cardiac and Vascular Institute of Miami Miami, FL Sheehan L. Raab, RT(R), RCIS NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Jeffrey J. Rade, MD Johns Hopkins Heart and Vascular Institute Baltimore, MD C. Venkata S. Ram, MD Dallas Nephrology Associates Dallas, TX The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Stephen R. Ramee, MD Ochsner Medical Center New Orleans, LA Ivan C. Rokos, MD Olive View Medical Center Sylmar, CA Victor L. Serebruany, MD, PhD HeartDrug Research Laboratories Towson, MD David P. Slovut, MD, PhD Montefiore Medical Center Bronx, NY Sunil V. Rao, MD Duke University Medical Center Durham, NC Matthew Romano, MD University of Michigan Medical Center Ann Arbor, MI Prediman K. Shah, MD Cedars-Sinai Medical Center Los Angeles, CA Mahmood K. Razavi, MD St. Joseph Cardiac and Vascular Center Orange, CA Martin T. Rothman, MD, MB, ChB Medtronic CardioVascular Santa Rosa, CA Mohsen Sharifi, MD Arizona Cardiovascular Consultants Mesa, AZ Richard Smalling, MD, PhD Memorial Hermann Heart and Vascular Institute Houston, TX Michael J. Reardon, MD The Methodist Hospital Houston, TX Serge Rousselle, DVM, DACVP Alizee Pathology Thurmont, MD Samin K. Sharma, MD Mount Sinai Medical Center New York, NY Vivek Y. Reddy, MD Mount Sinai Medical Center New York, NY Stanton J. Rowe Edwards Lifesciences Irvine, CA Leslee J. Shaw, PhD Emory University School of Medicine Atlanta, GA Mark Reisman, MD Swedish Heart and Vascular Institute Seattle, WA John H. Rundback, MD Holy Name Hospital Teaneck, NJ Fayaz Shawl, MD Washington Adventist Hospital Takoma Park, MD George R. Reiss, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Joseph F. Sabik, MD Cleveland Clinic Foundation Cleveland, OH James R. Shay, JD, BSE Shay Glenn LLP San Mateo, CA Robert D. Safian, MD William Beaumont Hospital Royal Oak, MI Marc E. Shelton, MD Prairie Cardiovascular Consultants, Ltd. Springfirld, IL Sean Salmon, MBA Medtronic Santa Rosa, CA Warren Sherman, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Frederic S. Rensic, MD Brigham and Women’s Hospital Boston, MA David G. Reuter, MD, PhD Seattle Childrens Hospital Kirkland, WA Matthew R. Reynolds, MD Beth Israel Deaconess Medical Center Boston, MA John F. Rhodes, MD Duke University Medical Center Durham, NC Randel Richner Neocure Group, LLC Sherborn, MA Charanjit S. Rihal, MD Mayo Clinic Rochester, MN Michael J. Rinaldi, MD Sanger Heart and Vascular Institute/ Carolinas Medical Center Charlotte, NC Marian K. Rippy, DVM, PhD Rippy Pathology Solutions Woodbury, MN David G. Rizik, MD Scottsdale Heart Group Scottsdale, AZ Krishna J. Rocha-Singh, MD Prairie Cardiovascular Consultants, Ltd. Springfield, IL Matthew T. Roe, MD, MHS Duke Clinical Research Institute Durham, NC Campbell Rogers, MD Cordis Corporation Bridgewater, NJ Jason H. Rogers, MD UC Davis Medical Center Sacramento, CA Joseph G. Rogers, MD Duke University School of Medicine Durham, NC Habib Samady, MD Emory University Hospital Atlanta, GA Timothy A. Sanborn, MD NorthShore University HealthSystem Evanston, IL Maurice E. Sarano, MD Mayo Clinic Rochester, MN Jorge F. Saucedo, MD OU Medical Center Oklahoma City, OK Gary L. Schaer, MD Rush University Medical Center Chicago, IL Robert M. Schainfeld, DO Massachusetts General Hospital Waltham, MA Richard A. Schatz, MD Scripps Clinic La Jolla, CA Peter A. Schneider, MD Kaiser Permanente Honolulu, HI Theodore L. Schreiber, MD Cardiovascular Consultants Warren, MI Daniel G. Schultz, MD Greenhealth Health LLC Washington, DC Allan Schwartz, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Robert S. Schwartz, MD Minneapolis Heart Institute Foundation Minneapolis, MN Craig R. Smith, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Richard Solomon, MD University of Vermont Burlington, VT Robert J. Sommer, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Paul Sorajja, MD Mayo Clinic Rochester, MN John A. Spertus, MD Mid America Heart Institute Kansas City, MO Robert J. Siegel, MD Cedars-Sinai Medical Center Los Angeles, CA Frank E. Silvestry, MD Hospital of the University of Pennsylvania Radnor, PA Daniel I. Simon, MD University Hospitals Case Medical Center Cleveland, OH Charles A. Simonton, MD Abbott Vascular Santa Clara, CA John Sninsky, PhD Celera Alameda, CA Paul A. Sobotka, MD Hennepin County Medical Center West St Paul, MN Mehdi H. Shishehbor, DO, MPH Cleveland Clinic Foundation Cleveland, OH Pamela P. Simons St. Jude Medical, Inc. Plymouth, MN Wade S. Smith, MD, PhD UCSF Medical Center San Francisco, CA Vankeepuran S. Srinivas, MD Montefiore Medical Center New York, NY Frederick G. St. Goar, MD Advanced Cardiovascular Specialists Mountain View, CA Richard S. Stack, MD Duke University Medical Center Chapel HIll, NC Anthony E. Steimle, MD Santa Clara Medical Center Santa Clara, CA John B. Simpson, MD, PhD Sequoia Hospital Redwood City, CA Allan Stewart, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Binoy K. Singh, MD Columbia University, Center for Interventional Vascular Therapy New York, NY Gregg W. Stone, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Varinder P. Singh, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Peter H. Stone, MD Brigham and Women’s Hospital Boston, MA Motasim Sirhan Elixir Medical Corporation Sunnyvale, CA Kristen Skelton Edwards Lifesciences Corporation Irvine, CA Marvin J. Slepian, MD University of Arizona Health Sciences Center Tucson, AZ Thomas D. Stuckey, MD Moses Cone Heart and Vascular Center Lebauer Cardiovascular Research Foundation Greensboro, NC H. Robert Superko, MD Saint Joseph’s Translational Research Institute Alameda, CA www . t c t c o n f e r e n c e . c o m 37 United States Faculty Lars G. Svensson, MD, PhD Cleveland Clinic Foundation Cleveland, OH Alfredo Trento, MD Cedars-Sinai Medical Center Los Angeles, CA Brian Whisenant, MD Intermountain Medical Center Salt Lake City, UT David X. Zhao, MD Vanderbilt Heart and Vascular Institute Nashville, TN Gilani Syed, MD UTMB Galveston Galveston, TX Thomas T. Tsai, MD, MSc Denver Veterans Affairs Medical Center Denver, CO Rodney White, MD Harbor-UCLA Medical Center Torrance, CA James P. Zidar, MD Rex Healthcare Raleigh, NC Jacqueline E. Tamis-Holland, MD St. Luke’s-Roosevelt Hospital New York, NY Sotirios Tsimikas, MD University of California San Diego San Diego, CA Mark H. Wholey, MD UPMC Shadyside Pittsburgh, PA David Zimrin, MD University of Maryland Medical Center Baltimore, MD Atsushi Tanaka, MD Massachusetts General Hospital Boston, MA Thomas M. Tu, MD Louisville Cardiology Medical Group Louisville, KY Michael H. Wholey, MD Christus Santa Rosa Medical Center San Antonio, TX William A. Zoghbi, MD American College of Cardiology Houston, TX Addis Taye Makuria, MD CVPath Institute, Inc. Gaithersburg, MD Mark A. Turco, MD Washington Adventist Hospital Takoma Park, MD Josiah N. Wilcox, PhD Medtronic CardioVascular Santa Rosa, CA Bram D. Zuckerman, MD US Food and Drug Administration Silver Spring, MD Addison A. Taylor, MD, PhD Baylor College of Medicine Houston, TX Zoltan G. Turi, MD Cooper University Hospital Camden, NJ Robert L. Wilensky, MD Hospital of the University of Pennsylvania Philadelphia, PA Guillermo Tearney, MD, PhD Massachusetts General Hospital Boston, MA E. Murat Tuzcu, MD Cleveland Clinic Foundation Cleveland, OH Jose M. Wiley, MD Mount Sinai Medical Center New York, NY Faramarz Tehrani, MD UC Davis Medical Center Sacramento, CA Takahiro Uchida, MD, PhD, MSc Boston Scientific Corporation Natick, MA David O. Williams, MD Brigham and Women’s Hospital Boston, MA Paul S. Teirstein, MD Scripps Clinic and Research Foundation La Jolla, CA Uma S. Valeti, MD University of Minnesota Minneapolis, MN Michael W. Tempelhof, MD Northwestern University Chicago, IL Renu Virmani, MD CVPath Institute, Inc. Gaithersburg, MD Mathew Williams, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY David E. Thaler, MD, PhD Tufts Medical Center Boston, MA William W. Voda, JD Arnold and Porter LLP Washington, DC Robert Thatcher, BSBA, MBA Cardiovascular Systems, Inc. St. Paul, MN Szilard Voros, MD Integrated Cardiovascular Research Group Atlanta, GA Craig A. Thompson, MD, MMSc Yale New Haven Hospital New Haven, CT Vinod H. Thourani, MD Emory University Hospital Midtown Atlanta, GA Craig M. Walker, MD Cardiovascular Institute of the South Houma, LA Stephen D. Wiviott, MD Brigham and Women’s Hospital Boston, MA S. Chiu Wong, MD NewYork-Presbyterian Hospital/ Weill Cornell Medical College New York, NY Larry L. Wood Edwards Lifesciences Irvine, CA Sergio Waxman, MD Lahey Clinic Burlington, MA Janet F. Wyman, DNPc ACCF Cardiac Catheterization and Intervention Committee Grosse Pointe, MI Jesse Weinberger, MD Mount Sinai Medical Center New York, NY R. Michael Wyman, MD Torrance Memorial Medical Center Torrance, CA Bonnie H. Weiner, MD, MSEC, MBA Worcester Medical Center Worcester, MA Jay S. Yadav, MD Piedmont Hospital Atlanta, GA Jonathan M. Tobis, MD UCLA Medical Center Los Angeles, CA Neil J. Weissman, MD Washington Hospital Center Washington, DC Steven J. Yakubov, MD Riverside Methodist Hospital Columbus, OH On Topaz, MD Charles George Veterans Affairs Medical Center Asheville, NC Giora Weisz, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Robert W. Yeh, MD, MBA Massachusetts General Hospital Boston, MA Eric J. Topol, MD Scripps Clinic La Jolla, CA Catherine P. Wentz US Food and Drug Administration Silver Spring, MD Jennifer A. Tremmel, MD Stanford University Medical Center Stanford, CA Grayson H. Wheatley, MD Arizona Heart Institute Phoenix, AZ Gary Thompson Abbott Vascular Santa Clara, CA Henry H. Ting, MD, MBA Mayo Clinic Rochester, MN Judy Tingley, RN, MPH Columbia University Medical Center, Health Policy and Management New York, NY 38 Ron Waksman, MD Cardiovascular Research Institute Washington, DC Robert Winchester, MD Columbia University Medical Center, Health Policy and Management New York, NY program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Alan C. Yeung, MD Stanford University Medical Center Stanford, CA Paul Yock, MD Stanford University Medical Center Stanford, CA Christopher K. Zarins, MD Stanford University Medical Center Stanford, CA The World’s Premier Interventional Experience TCT2011 LIve case sites and operators High-definition live case transmission sites span 21 locations around the globe. Live cases offer unique, invaluable learning opportunities for attendees. International Asan Medical Center Seoul, South Korea Soo-Jin Kang, MD, PhD Won-Jang Kim, MD, PhD Young-Hak Kim, MD, PhD Cheol-Whan Lee, MD, PhD Jong-Young Lee, MD, PhD Seung-Whan Lee, MD, PhD Duk-Woo Park, MD, PhD Seong-Wook Park, MD, PhD Seung-Jung Park, MD, PhD Auckland City Hospital Auckland, New Zealand Brendan Buckley, MBChB Brigid Connor, MBDCh Andrew Hill, MBChB Andrew Holden, MBChB Cardiovascular Centre, ZNA Middelheim Hospital Antwerp, Belgium Carl Convens, MD Glenn Van Langenhove, MD, PhD Stefan Verheye, MD, PhD Paul Vermeersch, MD, PhD First Affiliated Hospital of Nanjing Medical University Nanjing, China Shao-Liang Chen, MD Jie Qian, MD Shou-Jie Shan, MD Imad Sheiban, MD Fei Ye, MD Jun-Jie Zhand, MD ICPS Institut Hospitalier Jacques Cartier Massy, France Hakim Benamer, MD Thomas Hovasse, MD Thierry Lefevre, MD Marie-Claude Morice, MD Mirano General Hospital Mirano, Italy Andrea Pacchioni, MD Carlo Penzo, MD Bernhard Reimers, MD Salvatore Sacca, MD Francesco Versaci, MD Park Hospital Leipzig Leipzig, Germany Sven Braulich, MD Dierk Scheinert, MD Andrej Schmidt, MD Matthias Ulrich, MD Quebec Heart and Lung Institute Quebec City, Canada Daniel Doyle, MD Eric Dumont, MD Can M. Nguyen, MD Stephane Rinfret, MD Josep Rodes-Cabau, MD St. Paul’s Hospital/ University of British Columbia Vancouver, Canada Anson Cheung, MD John G. Webb, MD David A. Wood, MD Jian Ye, MD St Thomas’ Hospital London, United Kingdom Vinnie Bapat, MD Philip MacCarthy, MD Simon Redwood, MD Chris Young, MD Toyohashi Heart Center Toyohashi, Japan Osamu M. Katoh, MD Takahiko Suzuki, MD T r a n s c at h e t e r Cardiovascular Therapeutics University Hospital Bonn Bonn, Germany Piedmont Heart Institute Atlanta, GA Lutz Buellesfeld, MD Eberhard Grube, MD Lars Lickfett, MD Georg Nickenig, MD Nikos Werner, MD Chuck Ballard, MD Harold Carlson, MD Anna Kalynych, MD David E. Kandzari, MD Dimitri Karmpaliotis, MD Nicholas Lembo, MD United States Rush Center for Congenital and Structural Heart Disease at Rush University Medical Center Chicago, IL Cedars-Sinai Medical Center Los Angeles, CA Suhail Dohad, MD Saibal Kar, MD Mehran Khorsandi, MD Hooman Madyoon, MD Raj Makkar, MD Qi-Ling Cao, MD Ziyad M. Hijazi, MD, MPH Clifford Kavinsky, MD, PhD Damien Kenny, MD Mayo Clinic Rochester, MN Scripps Green Hospital La Jolla, CA Patricia Best, MD Allison Cabalka, MD Rajiv Gulati, MD Charanjit S. Rihal, MD Yaron Almagor, MD Antonio Colombo, MD Mathew J. Price, MD, Richard A. Schatz, MD Curtiss T. Stinis, MD Paul S. Teirstein, MD NewYork-Presbyterian Hospital/Columbia University Medical Center New York, NY Michael B. Collins, MD Khady Fall, MD William A. Gray, MD Osamu Katoh, MD Susheel Kodali, MD Edward M. Kreps, MD William L. Lombardi, MD Akiko Maehara, MD Philip Meyers, MD Jeffrey W. Moses, MD Tamim Nazif, MD Masahiko Ochiai, MD, PhD Jean-Michel Paradis, MD Anthony Pucilo, MD Prabhdeep Sandhu, MD Varinder P. Singh, MD Robert J. Sommer, MD Mathew Williams, MD Swedish Health Services Seattle, WA Robert M. Bersin, MD Amish J. Desai, MD Paul P. Huang, MD Thomas K. Jones, MD John Petersen II, MD Mark Reisman, MD University of California, Davis Medical Center Sacramento, CA David Dawson, MD Andrew T. Kwa, MD John R. Laird Jr, MD Reginald I. Low, MD William Pevec, MD Jason Rogers, MD Jeffrey Southard, MD Garrett Wong, MD Khung-Keong Yeo, MD University of Colorado Denver, CO John D. Carroll, MD www . t c t c o n f e r e n c e . c o m 39 TCT Comes to Miami in 2012 Save the date OCTOber 22-26, 2012 Mi ami Bea ch Co nv en tion Cent er MiaMi, florida w w w. t ct con f e re n c e . c o m The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics TCT for Nurses and Technologists . . ..................................42, 43 TCT for Surgeons........................................................................ 52 Scientific Symposia Chronic Total Occlusions: Basic and Expert Techniques............................ 43 Endovascular Intervention (Part 1).............................................................. 45 Interventional Innovation: Novel Therapies and the “Best” New Device Concepts for 2011................................................. 46 Left Main and Bifurcation Stenting: An Advanced Operator’s Workshop........................................................... 48 Strategies for Cardiovascular Repair: Stem Cells and Beyond.............................................................................. 49 The Drug-Eluting Stent Summit: Appropriate Utilization of Current Generation Devices................................................... 50 The Valvular Heart Disease Summit (Part 1): Aortic Valve Therapies................................................................................ 52 PFO and ASD Closure: Evolving Indications, Patient Selection, Devices, and Technique................................................. 53 New Patients for New Interventional Therapies.......................................... 54 Partnership Session: Angioplasty Summit-TCTAP...................................... 55 Evening Programs.............................................................................. 146 · san francisco, ca www.tctconference.com November 7, 2011 Featured Clinical Research I. Transcatheter Valve and STEMI/Heart Failure Therapies............................................................ 54 the Moscone Center Special Twilight Sessions Monday Board Review Course with Self-Assessment in Interventional Cardiology (Part 1).............................................. 42 41 MOnday, November 7 Board Review Course with Self-Assessment in Interventional Cardiology (Part 1) This session is not CE accredited for nurses. 8:00 am-6:00 Room 103 pm Central Concepts of PCI Moderators: Tayo A. Addo, George D. Dangas 8:00 am - Medical Statistics and Trial Design: Lessons from Recent Publications Stuart J. Pocock 8:30 am - Radiation Principles and Safety Stephen Balter 9:00 am - Femoral Vascular Access: Technique, Closure Devices, and Complications Robert J. Applegate 9:20 am - Radial Artery Access and Closure: Technique, Results, and Complications Varinder P. Singh 9:40 am - Break PCI Strategies, Indications, Guidelines, and Outcomes Moderators: Emmanouil S. Brilakis, George D. Dangas 10:00 am - PCI in Stable Coronary Artery Disease: Risk Stratification and Comparison with Medical and Surgical Alternatives Manish A. Parikh 10:30 am - PCI in ACS and Non-STEMI: Guidelines and Outcomes Emmanouil S. Brilakis 11:00 am - Primary PCI for STEMI: Guidelines, Strategies, and Outcomes Tayo A. Addo 11:30 am - Pharmacoinvasive Strategies (Facilitated, Rescue, and Transfer PCI) in STEMI Duane S. Pinto 12:00 pm - Cardiogenic Shock and Hemodynamic Support Alternatives Timothy A. Sanborn 12:30 pm - Lunch Break Interventional Pharmacology: Guidelines and Practice Outcomes Moderators: Tayo A. Addo, George D. Dangas 1:30 pm - Elective (Nonurgent) PCI Matthew J. Price 42 program · 2:00 pm - Acute Coronary Syndromes/NSTEMI Emmanouil S. Brilakis Case Presentations and Discussion with Integrated Audience Response 2:30 pm - PCI in STEMI Gregg W. Stone The Hybrid Approach to Coronary Revascularization: Best of Both Worlds? 3:00 pm - Platelet Reactivity, Genetics, and Thienopyridine Responsiveness Matthew J. Price Moderator: Thomas H. Maloney Discussants: Caesar Alvero, Ajay J. Kirtane, George R. Reiss, Mathew Williams 3:30 pm - Break 8:40 am - Review of the Data George R. Reiss Valvular and Structural Heart Disease 8:50 am - Case Introduction Thomas H. Maloney Moderators: Charanjit S. Rihal, Zoltan G. Turi 4:00 pm - Essentials of Aortic Valve Disease Hemodynamics and Intervention with Approved Devices (Including Related Guidelines) Susheel Kodali 4:30 pm - Essentials of Mitral Valve Disease Hemodynamics and Intervention with Approved Devices (Including Related Guidelines) Zoltan G. Turi 5:00 pm - Essentials of Adult Congenital Heart Disease Intervention: Diagnosis, Devices, and Outcomes Robert J. Sommer 5:30 pm - Specialized Structural Interventions: Approach to HOCM, Paravalvular Leaks, Acute MI VSD, and LAA Closure Charanjit S. Rihal 6:00 pm - Adjourn TCT for Nurses and Technologists 8:00 am-5:30 Room 102 pm 20th Annual Cardiovascular Nurse and Technologist Symposium Director: Marian C. Hawkey Co-Directors: Russell A. Brandwein, Michael Guiry, Nancy Houston Miller, Martina Kelly Speight, Hilary Nierenberg, Janet F. Wyman 8:00 am - Introduction and Review of Learning Objectives Marian C. Hawkey 8:10 am - TCT for Nurses and Technologists: Then and Now Moderator: Regina Deible Discussants: Ann Greenberg, Marian C. Hawkey, Alexandra J. Lansky, Thomas H. Maloney, Nancy Morris, Christopher M. Nelson T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 8:55 am - Initial Assessment: Cardiac Surgeon Mathew Williams 9:00 am - Initial Assessment: Interventionalist Ajay J. Kirtane 9:05 am - Case (Continued) Thomas H. Maloney 9:10 am - Discussion (Continued) 9:15 am - Cath Lab Staff Perspective on Preparedness for Hybrid Procedures Caesar Alvero 9:25 am - Case Conclusion and Final Comments Adapt to DAPT Moderator: George D. Dangas Discussants: Russell A. Brandwein, Matthew J. Price, Stephen D. Wiviott 9:30 am - Current Standards for DAPT Post-DES Stephen D. Wiviott 9:40 am - Choice and Dosing of Thienopyridines: Does It Really Matter? Matthew J. Price 9:50 am - Clinical Vignettes in Patients Requiring DAPT Russell A. Brandwein 10:00 am - DAPT of the Future George D. Dangas 10:10 am - Discussion Decisions in ACS/Primary PCI: Conflicts in Quality Moderator: Janet F. Wyman Discussants: Hitinder S. Gurm, Ralph G. Brindis, Akshay Khandelwal 10:20 am - Case Presentation Janet F. Wyman 10:30 am - Decision Making Akshay Khandelwal 10:40 am - Indications for Public Reporting Ralph G. Brindis The World’s Premier Interventional Experience TCT2011 10:55 am - Real-World Impact of Public Reporting Hitinder S. Gurm 2:55 pm - Discussion with Audience Q&A 11:05 am - Decision-Making in High-Risk Patients and the Impact of Public Reporting Transcatheter Heart Valve Therapies: Year in Review Moderator: Martina Kelly Speight Discussants: Jodi Akin, Julie Logan 11:10 am - Transcatheter Heart Valve Repair Julie Logan 11:25 am - Transcatheter Aortic Valve Replacement Martina Kelly Speight 11:45 am - PMA Challenges and Imperatives Jodi Akin 11:55 am - Final Discussion 12:00 pm - Adjourn with Lunch Pick-up Session III. The Mitral Valve: A Deep Dive Moderator: Thomas H. Maloney Discussants: James B. Hermiller Jr, Tim I. Martin, J. Wesley Todd 3:05 pm - Foundational Knowledge: Mitral Valve Anatomy, Function, and Associated Pathology Tim I. Martin Session II. Regional Updates for CTO PCI Practice Moderators: Gerald S. Werner, Alan C. Yeung Discussants: Alfredo R. Galassi, Bradley H. Strauss, Craig A. Thompson, Masahisa Yamane 9:02 am - EURO CTO Registry Alfredo R. Galassi 9:10 am - Japan CTO Registry Masahisa Yamane 9:18 am - US CTO Practice Trends Craig A. Thompson 3:25 pm - Hemodynamics of Mitral Stenosis and Mitral Regurgitation J. Wesley Todd 9:26 am - Canadian CTO Registry Bradley H. Strauss 3:50 pm - Future of Percutaneous Devices for the Treatment of Mitral Regurgitation James B. Hermiller Jr Session III. The Toolbox and Basic Techniques for CTO PCI Moderators: William L. Lombardi, Georgios Sianos Discussants: Christopher E. Buller, Alfredo R. Galassi, David E. Kandzari, Jeffrey W. Moses, Masahiko Ochiai, Sudhir Rathore, Stéphane Rinfret 4:10 pm - Discussion with Audience Q&A Session IV. Hands on Hearts Room 12 4:20 pm - Hands on Hearts 9:34 am - Discussion with Audience Q&A RCIS Review Course 5:30 pm - Adjourn Session I. Fundamental Knowledge Moderator: Thomas H. Maloney Discussants: Jeff Davis, Todd Ginapp, Robert S. Schwartz, George W. Vetrovec 9:42 am - Patient Selection and Indications for CTO PCI: A Contemporary Look Christopher E. Buller Scientific Symposia 9:52 am - Preprocedure Angiographic Review: Occlusion Morphology and Collateral Patterns: What I Look For Sudhir Rathore 12:15 pm - Introduction and Session Objectives Thomas H. Maloney 12:20 pm - Basics of the Heart and Related Structures Robert S. Schwartz 12:40 pm - Hemodynamics of the Normal Heart: Basic Understanding Todd Ginapp 1:00 pm - Coronary Angiography from the Interventional Cardiologist’s Perspective George W. Vetrovec 1:20 pm - The Heart of the Animal Kingdom: Comparing Human Hearts to Multiple Species Jeff Davis 1:40 pm - Discussion with Audience Q&A Session II. The Aortic Valve: A Deep Dive Moderator: Thomas H. Maloney Discussants: Stephen M. Foster, Susheel Kodali, Tim Lapp, 1:50 pm - Foundational Knowledge: Aortic Valve Anatomy, Function, and Associated Pathology Stephen M. Foster 2:10 pm - Hemodynamics of Aortic Stenosis and Aortic Insufficiency Tim Lapp Chronic Total Occlusions: Basic and Expert Techniques 8:00 am-6:10 Room 132 pm Session I. The Anatomy of the Chronic Total Occlusion Moderators: Yasushi Asakura, Masahiko Ochiai, Stéphane Rinfret Discussants: Masataka Nakano, Satoru Sumitsuji, Gerald S. Werner 8:00 am - CTO Plaque Anatomy: Histopathology and Micro CT Observations Masataka Nakano 8:10 am - Collateral Patterns and Significance in Coronary CTO Gerald S. Werner 8:20 am - Use of MSCT for CTO Procedural Planning Satoru Sumitsuji 8:30 am - IVUS Pattern Recognition During the CTO PCI Procedure Yasushi Asakura 8:40 am - IVUS Image Integration During the CTO PCI Procedure Satoru Sumitsuji 8:50 am - Discussion with Audience Q&A - N o v e m b e r 7 , 2 0 11 2:35 pm - Future of Percutaneous Devices for the Treatment of Aortic Stenosis Susheel Kodali monday 10:50 am - Scene from Star Trek: The Kobayashi Maru: Kirk and Spock Discuss the No-Win Scenario T r a n s c at h e t e r Cardiovascular Therapeutics 10:02 am - Patient Preparation, Vascular Access, and Cath Lab Readiness Stéphane Rinfret 10:12 am - Antegrade Direction 1: Guidewire Engineering, Shaping, Selection, and Technique Masahiko Ochiai 10:24 am - Antegrade Direction 2: Wire and Device-Based Coronary Reentry (with Case Examples) William L. Lombardi 10:36 am - Antegrade Direction 3: Wire Switch Strategies Within the Occluded Segment Alfredo R. Galassi 10:46 am - STAR and Mini-STAR: How to Salvage Success While Avoiding Complications Jeffrey W. Moses 10:56 am - Support Matters: Guide Selection and Support Augmentation Techniques (Balloon Anchoring, Guideliner, and More) Jeffrey W. Moses 11:08 am - Microcatheters, Balloons, and Stents: Tips and Tricks David E. Kandzari 11:18 am - Discussion with Audience Q&A www.tctconference.com 43 MOnday, November 7 Session IV. Retrograde Intervention Core Concepts Moderators: Jeffrey W. Moses, Etsuo Tsuchikane Discussants: Tony J. DeMartini, J. Aaron Grantham, Craig A. Thompson Debate III. The Retrograde Approach as an Initial Strategy for CTO PCI 11:33 am - Retrograde Step-by-Step Approach 1: Collateral Selection and Crossing Technique (with Case Examples) Tony J. DeMartini 1:34 pm - Think Backwards! Retrograde Techniques Are Essential in Many Procedures as a Primary Strategy! Tony J. DeMartini 11:48 am - Retrograde Step-by-Step Approach 2: Lesion Crossing, Reverse CART and CART Techniques, and Wire Externalization (with Case Examples) J. Aaron Grantham 1:42 pm - Discussion 12:03 pm - Putting It All Together: Hybrid Antegrade/Retrograde Approaches for CTO PCI (with Case Examples) Craig A. Thompson 12:18 pm - JAPAN Retrograde: A Large-Scale National Registry of the Retrograde Approach for Recanalization of Chronic Total Coronary Artery Occlusions Masahisa Yamane 12:26 pm - Discussion with Audience Q&A Session V. The Great CTO Technique Debates Moderators: Alfredo R. Galassi, Sudhir Rathore Discussants: Kenneth Chin, Thierry Corcos, Richard R. Heuser, Vincent On-Hing Kwok, Shigeru Saito, Bradley H. Strauss Debate I. The Role of Parallel Wire in 2011 and Beyond 12:38 pm - Parallel Wire Remains a Relevant Basic Technique for CTO PCI! Masahisa Yamane 12:46 pm - The Need for Parallel Wire No Longer Exists in the Era of Stiff Wires, Coronary Reentry, and Retrograde Approach! J. Aaron Grantham 12:54 pm - Moderated Discussion Debate II. How Important Is it to Stay Intraluminal During CTO PCI? 1:02 pm - Every Attempt Should Be Made to Stay Within CTO Plaque for Optimal Outcomes! Gerald S. Werner 1:10 pm - The End Justifies the Means: Use Subintimal and Subadventitial Pathways Freely! William L. Lombardi 1:26 pm - Antegrade First! Retrograde Techniques Should Be Reserved as a Final Resort! Mauro Carlino Session VI. CTO Failure Modes: Unsuccessful Cases from the Masters Moderators: Tony J. DeMartini, David J. Hildick-Smith Discussants: Yasushi Asakura, Yaling Han, Osamu Katoh, Sunao Nakamura, Ramon Quesada, Maarten J. Suttorp, Takahiko Suzuki 1:50 pm - Why CTO PCI Fails: A Contemporary Look Georgios Sianos 2:00 pm - Case 1: Failed CTO - Failure Analysis and What I’d Do Different Yaling Han 2:10 pm - Case 2: Failed CTO - Failure Analysis and What I’d Do Different Takahiko Suzuki 2:20 pm - Case 3: Failed CTO - Failure Analysis and What I’d Do Different Osamu Katoh 2:30 pm - Discussion with Audience Q&A Session VII. New Technologies for Coronary CTO PCI Moderators: Richard R. Heuser, R. Michael Wyman Discussants: M. Nicholas Burke, J. Aaron Grantham, Dimitri Karmpaliotis, Joachim Schofer, Georgios Sianos, Etsuo Tsuchikane 2:40 pm - New Wire Platforms for CTO PCI: How Are They Different, and Are They Really Better? Masahiko Ochiai program · 3:25 pm - Collagenase Update Bradley H. Strauss 3:35 pm - Forward Looking Intravascular Ultrasound Update Craig A. Thompson 3:45 pm - CT Angiographic Coregistration Update Gerald S. Werner 3:55 pm - Discussion with Audience Q&A Session VIII. CTO Complication Management Moderators: Anthony H. Gershlick, Craig A. Thompson Discussants: David Antoniucci, Mauro Carlino, Charles E. Chambers, Javier Escaned, Luis Gruberg, Osamu Katoh, Jeffrey W. Moses, Toshiya Muramatsu, Masahiko Ochiai, Etsuo Tsuchikane, Darren L. Walters 4:10 pm - Radiation Safety and Procedural Considerations Charles E. Chambers 4:22 pm - Periprocedural Renal Injury: Frequency, Impact, and Prevention Luis Gruberg 4:34 pm - Coronary Perforation Primer: Frequency, Causes, Prevention, and Management (Pericardiocentesis, Covered Stents, Coils, and More) Jeffrey W. Moses 4:49 pm - Intraprocedural Thrombosis and Ischemia Masahiko Ochiai 4:59 pm - Device Entrapment Javier Escaned 5:09 pm - Complications Unique to the Retrograde Approach Osamu Katoh Special Session: Crossboss and Stingray Coronary Reentry 5:24 pm - Case 4: CTO Complication - Root Cause and Management Etsuo Tsuchikane 2:50 pm - Review of Crossboss and Stingray Balloon/Wire Design Dimitri Karmpaliotis 5:34 pm - Case 5: CTO Complication - Root Cause and Management Goran K. Olivecrona 3:00 pm - Basic Crossboss and Stingray Technique Joachim Schofer 5:44 pm - Case 6: CTO Complication - Root Cause and Management Georgios Sianos 1:18 pm - Discussion 44 3:10 pm - Crossboss and Stingray Troubleshooting: Lesion Access, Sidebranch Redirection, Poor Reentry Targets, and More R. Michael Wyman 5:54 pm - Discussion with Audience Q&A 6:10 pm - Adjourn T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 pm Session I. Peripheral Arterial Disease: Diagnosis and Imaging Moderators: Michael R. Jaff, Robert M. Schainfeld Discussants: Herbert D. Aronow, Lindsay S. Machan 8:00 am - Statins and Atherosclerotic Vascular Disease: Which Vascular Beds Benefit? Herbert D. Aronow 8:10 am - The Zebra in the Room: Unusual Vascular Diseases the Interventionalist Needs to Know Robert M. Schainfeld 8:22 am - Selecting Imaging for PAD: CTA, MRA, or Duplex Lindsay S. Machan 8:34 am - Discussion with Audience Q&A Session II. Iliac and Femoropopliteal Intervention Moderators: John R. Laird Jr, Lindsay S. Machan Discussants: Lawrence A. Garcia, David B. Jessup, Hans Krankenberg, Thomas O. McNamara, D. Christopher Metzger, Michael J. Rinaldi, John H. Rundback, Mark H. Wholey, Thomas Zeller 8:45 am - The Endovascular Approach to Chronic Aortoiliac Occlusions: Methods, Tools, and Long-term Outcomes (And When to Opt for Surgery!) David B. Jessup 9:05 am - All Atherectomy Devices Are Not Created Equal: A Lesion-Specific Approach Based on Data and Experience Lawrence A. Garcia 9:15 am - Excimer Laser as Primary or Adjunctive Treatment for Calcium and Thrombus in PAD Thomas O. McNamara 9:25 am - Update on the MARIS Registry of 1,000 Patients Treated with Nitinol Stents Hans Krankenberg 9:35 am - Drug-Coated Balloons for Femoropopliteal Intervention: Devices, Trials, and Outcomes to Date Thomas Zeller 9:50 am - Managing Iliac and Femoropopliteal Restenosis: Incidence, Diagnostic Tools, and Treatment Strategies Michael J. Rinaldi 10:15 am - Endovascular Repair of Popliteal Aneurysm: Indications, Imaging, and Tips and Tricks John H. Rundback 10:25 am - Unraveling the Device Spaghetti: A Lesion-Specific Approach to SFA Intervention Thomas Zeller 10:37 am - Complications During Peripheral Intervention: Characterization, Planning, Avoidance, Recognition, and Management Hans Krankenberg 10:52 am - Is There Value in Embolic Protection for Lower Extremity Intervention? Mark H. Wholey 11:02 am - Discussion with Audience Q&A Session III. Emerging Approaches in Vascular Intervention Moderators: Thomas A. Ischinger, John H. Rundback Discussants: Gary M. Ansel, Mark W. Burket, William A. Gray, Michel Henry, David B. Jessup, John R. Laird Jr, Robert A. Lookstein, James F. McKinsey, Manish Mehta, Antonios A. Polydorou, Jason H. Rogers, Dierk Scheinert, On Topaz, Craig M. Walker 11:20 am - Stent Grafts vs. Bare Metal Stents for Occlusive SFA Disease: Three-Year Results of the VIBRANT Trial Gary M. Ansel 11:30 am - Twelve-Month Results from the COMPLETE SE Study of SFA Stenting John R. Laird Jr 11:40 am - Pedal Arteries as Important Targets for Reconstruction in CLI Craig M. Walker 11:50 am - Outcomes of Iliac Intervention Using a Co-Cr Balloon Expandable Stent: Final Results of the ACTIVE Study William A. Gray 12:00 pm - Covered Stents for Iliac Occlusive Disease: Twelve-Month Results of the ICARUS Trial John R. Laird Jr 12:10 pm - Long-term Follow-up with a Multilayer Stent for Treatment of Renal and Mesenteric Aneurysms Antonios A. Polydorou 12:20 pm - Out of the Coronaries and into the Periphery: The BridgePoint System for Lower Extremity CTOs David B. Jessup 12:30 pm - A Low-Profile EVAR Device with Inflatable Sealing Rings: Primary Outcomes from the Pivotal TriVascular Ovation Stent Graft Trial Manish Mehta 12:40 pm - Stenting the Popliteal Artery Using a Woven Nitinol Stent: Twelve-Month Outcomes from the Leipzig SUPERA Experience Dierk Scheinert - N o v e m b e r 7 , 2 0 11 8:00 am-6:00 Room 131 10:00 am - Recanalizing SFA Occlusions: Procedural Planning, Tools, Techniques, and Expected Success Rates D. Christopher Metzger monday Endovascular Intervention (Part 1) T r a n s c at h e t e r Cardiovascular Therapeutics 12:50 pm - Results of a First-in-Man Study Using a Multilayer Stent for Popliteal Aneurysm Michel Henry 1:00 pm - Back to the Future? Outcomes of Brachytherapy for SFA ISR Using a Rhenium 188-Filled Balloon Dierk Scheinert 1:10 pm - Fenestrated Grafts for Juxtarenal AAA: Outcomes from the US Registry James F. McKinsey 1:20 pm - Deep in the Pelvis: Indications and Methods for Internal Iliac Artery Intervention Mark W. Burket 1:30 pm - Deeper in the Pelvis: Status of Pudendal Artery Stenting for Erectile Dysfunction Jason H. Rogers 1:40 pm - Debulking the Critical Renal Stenosis: A New Approach to Renal Revascularization On Topaz 1:50 pm - Optimizing Intervention for Renal FMD: Angiography Is Not Enough Robert A. Lookstein 2:00 pm - Discussion with Audience Q&A Session IV. Critical Limb Ischemia and Infrapopliteal Intervention Moderators: Peter A. Schneider, David P. Slovut Discussants: Gary M. Ansel, Raghu Kolluri, Alex Powell, Craig M. Walker, Thomas Zeller 2:20 pm - Physiologic Testing and Adjunct Management of Patients Undergoing Intervention for Critical Limb Ischemia Raghu Kolluri 2:30 pm - The Approach to Tibial Intervention for CLI: Available Tools and Techniques, and Which Vessels Must Be Treated? Alex Powell 2:45 pm - DES Below the Knee in CLI: Results from YUKON-BTK, DESTINY, and ACHILLES Thomas Zeller 3:00 pm - Drug-Coated Balloons for Infrapopliteal Intervention Gary M. Ansel www.tctconference.com 45 MOnday, November 7 3:10 pm - Access Isn’t Everything—It’s the Only Thing! Tips and Tricks for Successful Vascular Approach to the Infrapopliteal Intervention Craig M. Walker Flash Debate III 3:20 pm - Discussion with Audience Q&A 5:20 pm - It’s Called New School for a Reason: Frontline Endovascular Therapy for Patients with SFA Disease! D. Christopher Metzger Session V. Renal and Mesenteric Intervention Moderators: Christopher J. Cooper, Greg Mishkel Discussants: Mark C. Bates, Michael J. Rinaldi, John H. Rundback, Thomas Zeller 3:35 pm - Essential Tools and Techniques for Renal Artery Intervention Christopher J. Cooper 3:47 pm - Avoiding and Managing Complications of Renal Intervention Mark C. Bates 3:59 pm - Predicting the Response to Intervention: Methods for Determining the “Correct” Renal Artery Stenosis to Treat John H. Rundback 4:09 pm - Managing the Restenotic Renal Artery Thomas Zeller 4:19 pm - Mesenteric Ischemia: Clinical Presentations, Diagnosis, and Indications for Intervention and Surgery Greg Mishkel 4:31 pm - Discussion with Audience Q&A 5:15 pm - Old School Is the Still the Best: Surgical Bypass Is Preferred for Long SFA Disease! Kenneth Ouriel 5:25 pm - Discussion and Vote Flash Debate IV 5:30 pm - Primary Bare Metal Stenting of the SFA Gives the Best Outcomes! Erich Minar 5:35 pm - The Data Are Limited for Bare Metal Stents in the SFA: They Should Be Only Applied Selectively! Tony Das 5:40 pm - Discussion and Vote Flash Debate V 5:45 pm - Data Don’t Lie: Renal Artery Intervention Is Dead in the Water! Robert D. Safian 5:50 pm - Nonsense! Renal Artery Intervention Is a Critically Important Component of Patient Care, and Here’s the Proof! Michael R. Jaff 5:55 pm - Discussion and Vote 6:00 pm - Adjourn Session VI. Flash Debates: Round One Moderators: Frank J. Criado, Dierk Scheinert Discussants: Robert M. Bersin, Tony Das, Michael R. Jaff, James F. McKinsey, D. Christopher Metzger, Erich Minar, Kenneth Ouriel, Robert D. Safian Interventional Innovation: Novel Therapies and the “Best” New Device Concepts for 2011 Flash Debate I Session I. Interventional Innovation: Process, Promise, and Realities in 2011 Moderators: Martin B. Leon, Paul Yock Discussants: Todd J. Brinton, Elazer R. Edelman, Peter J. Fitzgerald, Thomas J. Fogarty, Julio C. Palmaz 4:45 pm - Endovascular Repair of AAA and TAA Should Be Performed Exclusively by the Vascular Surgeon! James F. McKinsey 4:50 pm - In the Future These Repairs Will Be Percutaneous and Performed by the Nonsurgical Interventionalist! Robert M. Bersin 4:55 pm - Discussion and Vote Flash Debate II 5:00 pm - Drug-Eluting Stents for SFAPopliteal Disease: The New Standard of Care! Michael D. Dake 5:05 pm - Drug-Eluting Stents for SFAPopliteal Disease: Not So Fast! Tony Das 8:00 am-6:00 Room 134 pm 8:00 am - Key Elements of the Biodesign Process: Identify, Invent, and Implement Paul Yock 8:12 am - Discussion 8:15 am - The Innovative Process: Taught or Spontaneous? Todd J. Brinton, Peter J. Fitzgerald 8:27 am - Discussion 8:30 am - What’s Gone RIGHT! Innovation Is Still the Cornerstone of Less Invasive Interventional Therapy Elazer R. Edelman 5:10 pm - Discussion and Vote 46 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 8:45 am - Panel Discussion: Lessons from the Masters Moderators: Martin B. Leon, Paul Yock Discussants: Elazer R. Edelman, Thomas J. Fogarty, Stephen N. Oesterle, Julio C. Palmaz, John B. Simpson, Richard S. Stack 9:15 am - What’s Gone WRONG! The “Death Valley” of Medical Innovation: Current Disturbing Trends in the United States Martin B. Leon 9:30 am - Panel Discussion: Is There an Innovation Crisis in the United States? Moderators: Elazer R. Edelman, Martin B. Leon Discussants: Chad Cornell, Keith D. Dawkins, Andrew Farb, Tim A. Fischell, Paul A. LaViolette, Michael A. Mussallem, Charles A. Simonton, Mark A. Turco Session II. The Globalization of Innovation Moderators: Peter J. Fitzgerald, Ran Kornowski Discussants: Michael Buck, Hank Kucheman, Paul A. LaViolette, Daniel T. Lemaitre, Keyur H. Parikh, Sean Salmon, Jacques Seguin, Ashok Seth, Philip Wang 10:00 am - The New Medical Innovation Success Model: “Think Global”—Rationale, Facts, and Trends Peter J. Fitzgerald Regions of Greatest Interest 10:12 am - Israel: The “Start-up Nation” Ran Kornowski 10:22 am - Europe: Old-World Firepower Jacques Seguin 10:32 am - India: A Sleeping Giant Keyur H. Parikh 10:42 am - China: The 800-Pound Gorilla Philip Wang 10:52 am - Panel Discussion: Why Globalization Makes Sense Moderators: Peter J. Fitzgerald, Ran Kornowski Discussants: Michael Buck, Hank Kucheman, Daniel T. Lemaitre, Keyur H. Parikh, Sean Salmon, Jacques Seguin, Ashok Seth, Philip Wang, Bo Xu Session III. The Convergence of Med Tech and Info Tech (MT Meets IT) Moderators: Peter J. Fitzgerald, Dana G. Mead Jr Discussants: Donald Casey, Neal L. Eigler, C. Michael Gibson, William T. Harrington, Frederick G. St. Goar, Alan C. Yeung The World’s Premier Interventional Experience TCT2011 Industry Roundtable Moderators: Juan F. Granada, Chaim S. Lotan 11:42 am - Case Example 1: HEARTFLOW: Combining Physiology and Imaging Frederick G. St. Goar 11:52 am - Case Example 2: Medical iPad: Applications and Managing Heart Failure Neal L. Eigler 12:02 pm - Case Example 3: Cell Phone: Integration into Medical Practice Donald Casey 12:12 pm - Panel Discussion: Impact of IT on Medical Care, Cost, and Clinical Outcomes Moderators: Peter J. Fitzgerald, Dana G. Mead Jr Discussants: Donald Casey, Neal L. Eigler, C. Michael Gibson, William T. Harrington, Frederick G. St. Goar, Alan C. Yeung Session IV. Cath Lab of the Future Moderators: Louis A. Cannon, Jacques J. Koolen Discussants: Elchanan Bruckheimer, Samir R. Kapadia, Saibal Kar, Frederic H. Moll, Augusto D. Pichard, Amit Segev, Marvin J. Slepian, Giora Weisz Advanced Imaging 12:42 pm - 3-D (and 4-D) Angiography, Echo, and CTA Have Arrived! John D. Carroll 12:54 pm - Case Example: REALVIEW Holographic Imaging for Adult Congenital, Structural, and Valvular Heart Disease Elchanan Bruckheimer 1:05 pm - Discussion Telemanipulation and Robotics 2:00 pm - The ICI Vision of the Most Compelling Unmet Clinical Needs for the Next Decade Chaim S. Lotan 2:12 pm - Discussion Case Model Proposition I 2:15 pm - Modulating Sympathetic Nervous System Activity to Treat HTN and CHF Paul A. Sobotka 2:27 pm - Discussion 2:30 pm - Case Example 1: RF Ablation (ARDIAN) Robert J. Whitbourn 2:37 pm - Case Example 2: Local Drug Delivery (MERCATOR) Christopher D. Owens 4:10 pm - Case Example 1: BACKBEAT for HTN Therapy Daniel Burkhoff 4:20 pm - Case Example 2: The “TIC-TAC” Approach Stephen N. Oesterle 4:30 pm - Case Example 3: External Shock Therapy Debra S. Echt 4:40 pm - Discussion: Alternative Options for the Therapy of CHF and HTN Moderators: Juan F. Granada, Chaim S. Lotan Discussants: Daniel Burkhoff, Debra S. Echt, Stephen N. Oesterle, Robert S. Schwartz NonCardiovascular Transcatheter Therapies 4:55 pm - Transcatheter Less Invasive Therapies “Gone Wild”: Breakthrough Innovations in the Noncardiovascular Space Juan F. Granada 5:07 pm - Discussion 2:43 pm - Case Example 3: Focused Energy (The Gamma Knife Experience) John Adler 5:10 pm - Case Example 1: Interventional Orthopedics Gary S. Fanton 2:50 pm - Discussion: Challenges, Opportunities, and Therapeutic Approaches of Renal Denervation Therapies Moderators: Juan F. Granada, Chaim S. Lotan Discussants: John Adler, William A. Gray, Maurizio Menichelli, Christopher D. Owens, Paul A. Sobotka 5:20 pm - Case Example 2: Interventional ENT Rick Anderson Case Model Proposition II 3:05 pm - Implantable Sensors Can Prevent Adverse Events and Improve Management of HTN and CHF William T. Abraham 1:10 pm - History, Rationale, and Future Opportunities for Telemanipulation of Catheters and Devices Frederic H. Moll 3:17 pm - Discussion 1:22 pm - Case Example: CORINDUS Robotic-Assisted Angioplasty: Current Status and Distant Vision Giora Weisz 3:30 pm - Case Example 2: SAVACOR Future Directions Neal L. Eigler 1:32 pm - Panel Discussion: Dissecting the Basic Components of the Cath Lab of the Future Moderators: Louis A. Cannon, Jacques J. Koolen Discussants: Elchanan Bruckheimer, Samir R. Kapadia, Frederic H. Moll, Augusto D. Pichard, Amit Segev, Marvin J. Slepian, Giora Weisz 4:07 pm - Discussion - N o v e m b e r 7 , 2 0 11 Session V. Responding to the Next Clinical Needs In collaboration with Innovations in Cardiovascular Interventions monday 11:30 am - The Transforming Potential of Combining Innovative MT and IT: Can GE and Google Coexist and Thrive? Peter J. Fitzgerald T r a n s c at h e t e r Cardiovascular Therapeutics 5:30 pm - Case Example 3: Interventional Pulmonology Michael T. Baker 5:40 pm - Discussion: Lessons Learned from the Interventional Cardiology Field Moderators: Juan F. Granada, Chaim S. Lotan Discussants: Rick Anderson, Michael T. Baker, Gary S. Fanton, Peter J. Fitzgerald 6:00 pm - Adjourn 3:20 pm - Case Example 1: CARDIOMEMS Next Steps William T. Abraham 3:40 pm - Discussion: The Impact of Ambulatory Monitoring on Cost and Clinical Outcomes Moderators: William T. Abraham, Juan F. Granada, Chaim S. Lotan Discussants: Daniel Burkhoff, Neal L. Eigler, Frank Litvack Case Model Proposition III 3:55 pm - Novel Implantable Pacemakers and Advances in Resynchronization Therapies Robert S. Schwartz www.tctconference.com 47 MOnday, November 7 Left Main and Bifurcation Stenting: An Advanced Operator’s Workshop 8:00 am-6:10 Room 133 pm Session I. Core Concepts Moderators: James B. Hermiller Jr, David E. Kandzari Discussants: Remo Albiero, Alaide Chieffo, Akiko Maehara, Renu Virmani 8:00 am - How Are Left Main and Non-Left Main Bifurcations Unique, and How Should These Observations Affect the Interventional Approach 1: Insights from Pathology Renu Virmani 8:10 am - How Are Left Main and Non-Left Main Bifurcations Unique, and How Should These Observations Affect the Interventional Approach 2: Insights from Imaging Akiko Maehara 8:20 am - Coronary Bifurcation Treatment: Update from the European Bifurcation Club Remo Albiero 8:35 am - Predictors of Restenosis and Stent Thrombosis After One- and Two-Stent Techniques in Left Main and Non-Left Main Bifurcations Alaide Chieffo 8:47 am - Discussion with Audience Q&A Session II. Non-Left Main Bifurcations Moderators: Thierry Lefevre, David G. Rizik Discussants: Carlo Briguori, David J. Hildick-Smith, Bon-Kwon Koo, Gary S. Mintz, Issam D. Moussa, Stefan Verheye 9:02 am - Does PCI of Non-Left Main Bifurcation Lesions Impair the Acute and Late Results of Multivessel Intervention? Insights from SYNTAX Patrick W. Serruys 9:12 am - Technical Approach to Non-Left Main Bifurcations: Integrated Lessons from Nordic, CACTUS, BBC ONE, and EBC TWO David J. Hildick-Smith 9:24 am - A Prospective, Randomized Trial of Aggressive vs. Conservative Sidebranch Dilation Strategies After Provisional Stenting of Bifurcation Lesions Hyeon-Cheol Gwon 9:34 am - When to Favor a Planned Two-Stent Technique in Non-Left Main Bifurcations (and Which One)? Issam D. Moussa 9:49 am - Use of IVUS to Guide Complex Non-Left Main Bifurcation Stenting Gary S. Mintz 48 program · 10:01 am - Use of FFR to Guide Complex Non-Left Main Bifurcation Stenting Bon-Kwon Koo 12:38 pm - Does Hybrid PCI/CABG Have a Role for Left Main Disease? Leif Thuesen 10:13 am - Sidebranch Preservation Strategies 1: Debulking and Scoring Jeffrey W. Moses 12:46 pm - Are PCI Results Improving in Left Main Disease with Advances in Stent Technology, Pharmacology, and Technique? Thierry Lefevre 10:23 am - Sidebranch Preservation Strategies 2: The GLIDER Balloon Carlo Briguori 10:31 am - Sidebranch Preservation Strategies 3: Dedicated Stents Stefan Verheye 10:46 am - TRYTON: Design and Status of the First US IDE Dedicated Bifurcation Stent Trial Martin B. Leon 10:51 am - Discussion with Audience Q&A Session III. Management of Complex Non-Left Main Bifurcations: An Operator’s Guide Moderators: Stephen G. Ellis, Marie-Claude Morice Discussants: Antonio Colombo, Fernando Cura, Jens Flensted Lassen, Thierry Lefevre 11:01 am - My Top 10 Techniques to Surviving Complex Non-Left Main Bifurcations Antonio Colombo 11:16 am - Case Review 1: How Did I Treat This Complex Non-Left Main Bifurcation? Fernando Cura 11:26 am - Case Review 2: How Did I Treat This Complex Non-Left Main Bifurcation? Jens Flensted Lassen 11:36 am - Case Review 3: How Did I Treat This Complex Non-Left Main Trifurcation? Thierry Lefevre 11:46 am - Discussion with Audience Q&A Session IV. Left Main Revascularization: PCI vs. CABG Moderators: Gregg W. Stone, David Taggart Discussants: William E. Cohn, Andrejs Erglis, Raj Makkar, James R. Margolis, Friedrich W. Mohr, John D. Puskas, Corrado Tamburino 12:01 pm - PCI vs. CABG for Left Main Disease: Today’s Data: LEMANS, PRECOMBAT, SYNTAX LM, and the MAIN COMPARE Registry Young-Hak Kim 12:16 pm - Four-Year Results of the Left Main Cohort from the SYNTAX Trial Marie-Claude Morice 12:28 pm - Left Main PCI and CABG: Trends from Europe Keith G. Oldroyd T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 1:01 pm - Are Surgical Results Improving in Left Main Disease, and What Is the State of the Art? Michael J. Mack 1:16 pm - The NOBLE Trial: Design, Status, and Timelines Leif Thuesen 1:26 pm - The EXCEL Trial: Design, Status, and Timelines Gregg W. Stone 1:36 pm - Discussion: Left Main PCI vs. CABG: EU and US Perspectives Session V. Risk Stratification in Left Main Disease Moderators: Davide Capodanno, Seung-Jung Park Discussants: Bernard De Bruyne, A. Pieter Kappetein, Raj Makkar, Marie-Angele Morel, Tullio Palmerini 1:56 pm - Outcomes of Left Main PCI: Factors Influencing Prognosis Raj Makkar 2:08 pm - A Primer in Calculating the Syntax Score Marie-Angele Morel 2:18 pm - CREDO-Kyoto PCI/CABG Registry Cohort-2: A Large-Scale Multicenter Registry Comparing the Outcomes of Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients with Left Main Disease Hiroki Shiomi 2:26 pm - How Well Do Cardiologists Calculate the Syntax Score (and Where Are Mistakes Commonly Made)? Tullio Palmerini 2:36 pm - Reflections on the Ideal RiskStratification Tool: Beyond the Syntax Score Patrick W. Serruys 2:48 pm - Functional vs. Anatomic Revascularization: Surgical Perspectives A. Pieter Kappetein 2:58 pm - Functional vs. Anatomic Revascularization: Interventional Perspectives Bernard De Bruyne 3:08 pm - Discussion with Audience Q&A The World’s Premier Interventional Experience TCT2011 3:33 pm - Evaluating Left Main Severity: The Case for FFR Michalis Hamilos 3:43 pm - Evaluating Left Main Severity: The Case for IVUS Stéphane Rinfret 3:53 pm - Discussion with Audience Q&A Session VII. Left Main PCI: Special Situations Moderators: Run-Lin Gao, Leif Thuesen Discussants: Adrian P. Banning, Michael S. Lee, John A. Ormiston 4:05 pm - Left Main Intervention During Primary PCI for STEMI: Technique and Outcomes Michael S. Lee 4:17 pm - Geometric Considerations and Physical Constraints of Current DES as it Applies to Distal Left Main Stenting John A. Ormiston 4:29 pm - Restenosis After Left Main Stenting: Frequency, Clinical Presentation, Management, and Outcomes Adrian P. Banning 4:41 pm - Is There a Need for Dedicated Stents for the Distal Left Main Bifurcation (and What Are the Contenders)? Martin B. Leon 4:53 pm - Discussion with Audience Q&A Session VIII. Case Reviews in Complex Left Main PCI Moderators: Antonio Colombo, Corrado Tamburino Discussants: Fernando Alfonso, Andrejs Erglis, Srihari S. Naidu, Erick Schampaert, Paul S. Teirstein 5:05 pm - How Did I Treat This Complex Distal Left Main Bifurcation? (Part 1) Andrejs Erglis 5:15 pm - How Did I Treat This Complex Distal Left Main Bifurcation? (Part 2) Erick Schampaert 5:25 pm - How Did I Treat This Complex Calcified Left Main? Fernando Alfonso 5:35 pm - How Did I Treat This Complex Distal Left Main Trifurcation? Paul S. Teirstein 5:55 pm - Discussion with Audience Q&A 6:10 pm - Adjourn Strategies for Cardiovascular Repair: Stem Cells and Beyond 8:00 am-6:00 pm Room 123 Moderators: Jozef Bartunek, Francisco Fernandez-Aviles, Amit Patel, Warren Sherman Cell-Scape 2011 Moderator: Warren Sherman 8:00 am - Symposium Overview Warren Sherman Session I. The Framework of Cardiovascular Repair: Upgrading to v.2012 Moderators: Atta Behfar, Stefanie Dimmeler, Marc S. Penn Discussants: Karen Christman, Silviu Itescu 8:15 am - Biomechanisms: Making Optimal Use of What Is Known Stefanie Dimmeler 8:30 am - Naive vs. Guided Cells for Heart Repair: The Role for Autologous Cardiopoietic Platforms Atta Behfar 8:45 am - “A Cell for All Seasons”: Current Evidence and New Concepts for the Multipotency of Mesenchymal Cells Silviu Itescu 9:00 am - Myocardial Matrix and Ventricular Remodelling: Promises from Tissue Engineering Karen Christman 9:15 am - Discussion with Audience Q&A Session II. Critical Limb Ischemia: The Vascular Infrastructure of Regenerative Medicine Moderators: Brian H. Annex, Stephen E. Epstein Discussants: Timothy D. Henry, Amit Patel, Vincent J. Pompili, Andreas M. Zeiher 9:35 am - Strategies for Cellular Intervention in Peripheral Vascular Disease Brian H. Annex 9:50 am - Marrow-Derived Stem Cell Therapy in Chronic Limb Ischemia: Focus on Point-of-Care Processing Vincent J. Pompili 10:05 am - Combined Delivery Options for Cell Therapy in PAD: The PROVASA Study Andreas M. Zeiher 10:20 am - Gene Therapy for Peripheral Artery Disease: New Agents, Early Data Timothy D. Henry 10:35 am - Clinical Trials for Critical Limb Ischemia: Forging Ahead with Phase 3 Studies Amit Patel 10:50 am - Discussion with Audience Q&A Session III. Stem Cells for Cardiac Repair in the Acute Setting Moderators: Jozef Bartunek, Hyo-Soo Kim Discussants: Henricus J. Duckers, Francisco Fernandez-Aviles, Warren Sherman, Jochen Wöhrle, Andreas M. Zeiher - N o v e m b e r 7 , 2 0 11 3:25 pm - Limitations of Angiography in Evaluating the Left Main Coronary Artery Alexandra J. Lansky 5:45 pm - How Did I Treat This Complex Left Main in This Patient with Severely Depressed Left Ventricular Function? Srihari S. Naidu monday Session VI. Left Main Assessment Moderators: Alexandra J. Lansky, Erick Schampaert Discussants: Sorin J. Brener, Michalis Hamilos, Stéphane Rinfret T r a n s c at h e t e r Cardiovascular Therapeutics 11:10 am - Bone Marrow Mobilization, Alone or in Combination with Cell Transplantation, in STEMI: Lessons from TECAM-2 Francisco Fernandez-Aviles 11:25 am - Two-Year Results of a Randomized, Double-Blind, Placebo-Controlled Trial (SCAMI) with Serial Cardiac Magnetic Resonance Imaging Jochen Wöhrle 11:40 am - Adipose Cells for STEMI: APOLLO and ADVANCE Randomized Trials Henricus J. Duckers 11:55 am - Bone Marrow Cell Transfer for STEMI: The BAMI Program Andreas M. Zeiher 12:10 pm - MAGIC Study Program: Molecular Modification of Stem Cells in the Clinic Hyo-Soo Kim 12:25 pm - Discussion with Audience Q&A 12:45 pm - Lunch Break Session IV. Stem Cells for Cardiac Repair in the Chronic Setting Moderators: Joshua M. Hare, Emerson C. Perin Discussants: Jozef Bartunek, Nabil Dib, Francisco Fernandez-Aviles, Timothy D. Henry, Marc S. Penn 1:45 pm - Final Results at 18 Months of the PRECISE Trial for Refractory Angina Francisco Fernandez-Aviles 2:00 pm - SDF-1: Heart Failure and Multisystem Applications Marc S. Penn 2:15 pm - Refractory Angina: The Mounting Case for Stem Cells Timothy D. Henry 2:30 pm - Lineage-Specified Mesenchymal Cells in Patients with Chronic Left Ventricular Dysfunction: Lessons from the C-CURE Trial Jozef Bartunek www.tctconference.com 49 MOnday, November 7 2:45 pm - Allogenic Cells for Chronic Left Ventricular Dysfunction: The US Experience and Beyond Nabil Dib 3:00 pm - Discussion with Audience Q&A Session V. Optimizing Delivery and Retention Moderators: Jonathan M. Hill, Amit Patel Discussants: Joshua M. Hare, Emerson C. Perin, Warren Sherman 3:20 pm - IV Delivery, Homing, and Biodistribution: Implications for the Clinical Setting Joshua M. Hare 3:30 pm - Present and Future of Transcatheter Endomyocardial Stem Cell Delivery Emerson C. Perin 3:40 pm - Transvascular Delivery of Biologic Agents: Techniques and Patients Warren Sherman 3:50 pm - Surgical Delivery: Which Patients, Which Products, and When? Amit Patel 4:00 pm - Discussion with Audience Q&A Session VI. Clinical Directions: New Biologics, New Patients Moderators: Francisco Fernandez-Aviles, Andreas M. Zeiher Discussants: Nicolas A.F. Chronos, Robert A. Kloner, Randall J. Lee, Jonathan Leor 4:15 pm - Pediatric Interventions: Autologous Progenitors for Congenital Myocardial Disease Andrejs Erglis 4:25 pm - Therapeutic Impact of B-Cells After Cardiac Ischemia Nicolas A.F. Chronos 4:35 pm - Cardiac Surgery and Ventricular Geometry: Clinical Experience with a Novel Agent Randall J. Lee 4:45 pm - Induced Pluripotent Cells and Embryonic Stem Cells: Promises to Keep? Robert A. Kloner 4:55 pm - Noncellular Approaches to Limiting Infarct Expansion: How Soon, and for Which Patients? Jonathan Leor 5:05 pm - Discussion with Audience Q&A 50 program · Cell Therapy and Cardiovascular Repair State of the Union Moderator: Jonathan M. Hill 5:25 pm - Summary, Insights, and Future Directions Jonathan M. Hill 6:00 pm - Adjourn The Drug-Eluting Stent Summit: Appropriate Utilization of Current Generation Devices 8:00 am-6:10 Room 104 pm Session I. DES as a Mature Subspecialty Moderators: Sigmund Silber, Peter Wenaweser Discussants: Edoardo Camenzind, Bernard R. Chevalier, David J. Cohen, David J. Hildick-Smith, Mitchell W. Krucoff, Jeffrey W. Moses 8:00 am - Featured Lecture: From the ESC Firestorm to the Relatively Calm Seas of 2011: What Have We Learned? Edoardo Camenzind Opening Controversy: Appropriate Utilization of BMS vs. DES 8:12 am - Today’s DES Makes BMS Nearly Obsolete! David J. Hildick-Smith 8:22 am - Outcomes and Economic Data Argue for a Rational Mix of BMS and DES! David J. Cohen 8:32 am - Discussion 8:44 am - Moderated Industry Roundtable: What Are the Targets to Further Improve DES? Are Current Generation DES So Good and Are Reimbursements Such as to Inhibit Further Investment? Moderators: Mitchell W. Krucoff, Gregg W. Stone Discussants: Keith D. Dawkins, Jeffrey B. Jump, Campbell Rogers, Sean Salmon, Charles A. Simonton, Mark A. Turco Session II. DES Selection for Unsettled Indications Moderators: Ian T. Meredith, Gregg W. Stone Discussants: Christoph A. Kaiser, Elvin Kedhi, Roxana Mehran, Maurizio Menichelli, Flavio L. Ribichini, Manel Sabate, Francesco Saia, Paul S. Teirstein, Glenn Van Langenhove, Bernhard Witzenbichler T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Debate: DES vs. BMS During Primary PCI in STEMI: Clinical Equipoise or Pathologic Fear? 8:58 am - The Case for Near Universal DES Use! Bernhard Witzenbichler 9:06 am - The Case for Near Universal BMS Use! Francesco Saia 9:14 am - The Case for Selective Use! Roxana Mehran 9:22 am - Everolimus-Eluting Stents vs. BMS in STEMI: The EXAMINATION Trial Results Manel Sabate 9:30 am - Do DES in STEMI Increase the Rates of Late Stent Thrombosis Compared to BMS? The DESERT Cooperation Giuseppe De Luca 9:38 am - Special Lecture: Can a History Be Accurately Taken Prior to PCI in STEMI Sufficient to Inform BMS vs. DES Use? The GHOST Study Maurizio Menichelli 9:48 am - DES Use in Simple Lesions in Large Vessels: Latest BASKET-PROVE Results Christoph A. Kaiser 9:58 am - DES in Complex Multivessel Disease: The SYNTAX Trial at Four Years: Overall Results and Breakdown of the 3VD Cohort Patrick W. Serruys 10:10 am - DES vs. BMS in SVG Lesions: Routine, Selective, or Rarely? Review of Randomized and Registry Data Glenn Van Langenhove Two Interesting Perspectives 10:20 am - Would SYNTAX Have Shown Equivalence Between DES and CABG Had a Potent Second Generation Device Been Used? Elvin Kedhi 10:28 am - Would FAME Have Been Negative Had Second Generation DES Been Exclusively Used? Ian T. Meredith When Should Cath Plus Ad Hoc PCI Be Allowed? 10:36 am - European Perspectives Flavio L. Ribichini 10:46 am - US Perspectives Paul S. Teirstein 10:56 am - Discussion The World’s Premier Interventional Experience TCT2011 11:11 am - Stent Thrombosis State of Knowledge: Mechanisms, Frequency, Timing, and Implications Joost Daemen 1:31 pm - When DES Restenose: Root Causes and Diagnostic Evaluation Antonio Colombo 11:26 am - Does Stent Thrombosis Start Early? Insights from Angioscopy Yasunori Ueda 11:34 am - Differences in Early and Late Stent Thrombosis with BMS vs DES: Insights from OCT Takashi Akasaka 11:44 am - Relationship Between Stent Malapposition and Stent Thrombosis: Effector or Innocent Bystander? Gary S. Mintz 11:54 am - Might OCT Guidance Be Used to Determine When It’s Safe to Discontinue DAPT? Giulio Guagliumi 12:06 pm - Pharmacotherapeutic Considerations to Reduce Stent Thrombosis 1: Appropriate Use of Prasugrel and Ticagrelor Dean J. Kereiakes 1:43 pm - Late Catch-up After First and Second Generation DES: Angiographic and IVUS Phenomena vs. Clinical Relevance Robert A. Byrne 1:53 pm - New Insights into Strut Fracture and DES Restenosis David E. Kandzari 4:41 pm - Everolimus-Eluting Stents: Three-Year COMPARE Results Peter C. Smits 2:17 pm - Treatment of DES In-Stent Restenosis: A Rationale Algorithm with Emerging Evidence Fernando Alfonso 4:56 pm - Sirolimus-Eluting Stents vs. EES: Meta-analysis of Overall Results Hyo-Soo Kim 2:29 pm - Use of Drug-Coated Balloons to Treat DES In-Stent Restenosis: First or Last Option? Alaide Chieffo 3:04 pm - Case 2: What Is the Cause of This DES Restenosis? Thomas A. Ischinger Stump the Panel Cases 1:11 pm - Case 1: What Is the Cause of This Stent Thrombosis? Jose M. de la Torre Hernandez 1:21 pm - Case 2: What Is the Cause of This Stent Thrombosis? Upendra Kaul 4:16 pm - Comparison of Zotarolimus-Eluting (Resolute) and Sirolimus-Eluting Stents in Long Coronary Artery Lesions: The Randomized LONG-DES IV Trial Seung-Jung Park 2:09 pm - Implications of Aneurysm Formation After DES Daljeet S. Gambhir 12:28 pm - Strategies to Prevent Stent Thrombosis When DAPT Must Be Discontinued Early Ajay J. Kirtane 12:56 pm - Discussion 4:01 pm - Zotarolimus-Eluting (Endeavor) Stents 2011/2012: Final Five-Year Trial Results and Clinical Use Recommendations for Patient Selection David E. Kandzari 4:31 pm - Everolimus-Eluting Stents 2011/2012: Stent Design Evolution, Clinical Trial Update Gregg W. Stone 2:39 pm - Discussion 12:48 pm - Operator Techniques to Reduce Stent Thrombosis Antonio Colombo 3:46 pm - Paclitaxel-Eluting Stents 2011/2012: New Data, Appropriate Utilization Louis A. Cannon 2:01 pm - Implications of Peri-stent Contrast Staining After DES Takeshi Kimura 12:16 pm - Pharmacotherapeutic Considerations to Reduce Stent Thrombosis 2: DAPT Duration 6 vs. 12 vs. 24 Months: Review of Completed Trials and Insights from the DAPT Trial Enrollment Laura Mauri 12:38 pm - Can DAPT be Discontinued Early with Selected DES? Insights from the SPIRIT and XIENCE USA Trials James B. Hermiller Jr 3:36 pm - How to Select DES: The Pathologist’s View Renu Virmani Stump the Panel Cases 2:54 pm - Case 1: What Is the Cause of This DES Restenosis? Robert J. Whitbourn Session V. DES Program Update: Today’s Generation Moderators: Steven R. Bailey, Dean J. Kereiakes Discussants: Louis A. Cannon, David E. Kandzari, Hyo-Soo Kim, Martin B. Leon, Tullio Palmerini, Seung-Jung Park, Peter C. Smits, Gregg W. Stone, Renu Virmani, Clemens von Birgelen 3:14 pm - How to Select DES: Geometry, Recoil, Strut Thickness, and Bifurcation Considerations John A. Ormiston - N o v e m b e r 7 , 2 0 11 Session IV. DES Restenosis: New Insights to Mechanisms, Prevention, and Treatment Moderators: Fernando Alfonso, Peter J. Fitzgerald Discussants: Robert A. Byrne, Alaide Chieffo, Daljeet S. Gambhir, David E. Kandzari, Upendra Kaul, Takeshi Kimura, Ajay J. Kirtane monday Session III. Stent Thrombosis: New Insights to Mechanisms, Prevention, and Treatment Moderators: Giulio Guagliumi, Paul S. Teirstein Discussants: Takashi Akasaka, Joost Daemen, Dean J. Kereiakes, Laura Mauri, Gary S. Mintz, Yasunori Ueda, Marco Valgimigli T r a n s c at h e t e r Cardiovascular Therapeutics 5:04 pm - Sirolimus-Eluting Stents vs. EES: Focus on Stent Thrombosis Tullio Palmerini 5:12 pm - Zotarolimus-Eluting (Resolute) Stents 2011/2012: Emerging Data from Randomized Trials and Registries Martin B. Leon 5:20 pm - Discussion Session VI. Emerging Noncoronary DES Applications Moderators: Michael D. Dake, David E. Kandzari Discussants: Lindsay S. Machan, Jason H. Rogers 5:35 pm - Evolution and Current Status of DES Use in the SFA and Below the Knee Lindsay S. Machan 5:47 pm - Drug-Eluting Stents for the Treatment of Erectile Dysfunction: Results of the ZEN Trial Jason H. Rogers 5:57 pm - Discussion 6:10 pm - Adjourn 3:26 pm - How to Select DES: Do Differences in Polymer Coating Consistency, Defects, and Integrity Exist (and Do They Matter)? Clemens von Birgelen www.tctconference.com 51 MOnday, November 7 The Valvular Heart Disease Summit (Part 1): Aortic Valve Therapies 8:00 am-7:00 Room 135 pm Session I. Aortic Stenosis: Pathophysiology, Diagnosis, and Treatment Moderators: Robert O. Bonow, Maurice E. Sarano Discussants: Michael J. Davidson, Craig R. Smith, E. Murat Tuzcu, Robert Winchester 8:00 am - Echocardiographic Keys to Diagnosing Aortic Stenosis: What’s Clinically Meaningful? Maurice E. Sarano 8:12 am - Discussion 8:15 am - Is Aortic Stenosis an Inflammatory Disease? New Laboratory Observations and Clinical Implications Robert Winchester 8:27 am - Discussion 8:30 am - How to Manage Patients with Aortic Stenosis: Guidelines, Controversies, and Clinical Pearls Robert O. Bonow 8:42 am - Discussion 8:45 am - Surgical Results in High-Risk Patients with Aortic Stenosis: Insights from PARTNER Craig R. Smith 8:55 am - Discussion 8:58 am - Are Outcomes Improved After Minimally Invasive Aortic Valve Surgery? Michael J. Davidson 9:08 am - Discussion 9:12 am - Indications, Results, and Complications of Balloon Aortic Valvuloplasty in the Era of TAVR: Lessons from PARTNER and Other Experiences E. Murat Tuzcu 9:45 am - Are Animal Studies with Transcatheter Aortic Valves Meaningful? Juan F. Granada 9:55 am - Analysis of Human Necropsy Transcatheter Heart Valve Specimens: Valve Design Differences, Durability Predictions, and Comparison with Surgical Valves Renu Virmani 10:05 am - Discussion 10:15 am - TAVR Update 2011: The Year in Review Martin B. Leon 10:30 am - VARC-2 Update: A Revised Roadmap for TAVR Clinical Research Patrick W. Serruys 10:42 am - Discussion Provocative Debate: TAVR Clinical Use Patterns: Disciplined Appropriate Growth vs. Uncontrolled Inappropriate Over use 10:45 am - “Risk Creep” Is Exaggerated: The Pie Is Growing! Martyn R. Thomas 10:55 am - Surgery Is Being Unfairly Cannibalized and Surgical Volumes Are Declining! Friedrich W. Mohr 11:05 am - Rebuttal and Discussion Session III. TAVR: Case Selection Considerations Moderators: Gregory P. Fontana, Jean-Claude Laborde Discussants: Stephen J.D. Brecker, Philip Green, Michael J. Mack, D. Craig Miller, Michael J. Reardon, Lars G. Svensson 11:15 am - The Proper Use (and Abuse) of Risk Algorithms: “New” (and Improved) STS and EuroSCORE and Beyond Michael J. Mack 9:22 am - Discussion 11:25 am - Discussion Session II. The TAVR Era: Historical Perspectives, Basic Concepts, and Status Updates Moderators: Alain G. Cribier, Michael J. Mack Discussants: Henning Rud Andersen, Juan F. Granada, Friedrich W. Mohr, Patrick W. Serruys, Martyn R. Thomas, Renu Virmani, John G. Webb Characterizing and Defining the “Inoperable” or “Extreme Risk” Aortic Stenosis Patient 9:25 am - TAVR Reflections 1: Concept Genesis and Early Animal Studies Henning Rud Andersen 52 9:35 am - TAVR Reflections 2: The Often Agonizing Path from Concept to Clinical Reality Alain G. Cribier program · 11:28 am - Viewpoints from PARTNER Lars G. Svensson 11:36 am - Viewpoints from the US CoreValve Study Michael J. Reardon 11:44 am - Discussion 11:50 am - Understanding the Frailty Phenotype: Objective Criteria and Implications for TAVR Case Selection Philip Green T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 12:00 pm - Discussion 12:03 pm - When Is an Aortic Stenosis Patient “Too Sick to Treat”? The Cohort C Patient (with Case Examples) D. Craig Miller 12:13 pm - Discussion 12:23 pm - Which Lower-Risk Aortic Stenosis Patients Are Appropriate TAVR Candidates TODAY? (with Case Examples) Stephen J.D. Brecker 12:33 pm - Discussion Session IV. Aortic Stenosis Clinical Case Conundrums: How to Manage a Patient with. . . . Moderators: Blase A. Carabello, D. Craig Miller Discussants: Robert O. Bonow, Howard C. Herrmann, Susheel Kodali, Reginald I. Low, Ganesh Manoharan, Josep Rodes-Cabau 12:35 pm - “Asymptomatic” Severe Aortic Stenosis with Case Examples: Exercise Testing and Elderly with Comorbidities Allan Schwartz 12:45 pm - Discussion 12:50 pm - Low-Flow, Low-Gradient Aortic Stenosis: With and Without Contractile Reserve and Clinical Outcomes Philippe Pibarot 1:00 pm - Low-Flow, Low-Gradient Aortic Stenosis: Case Example Nirat Beohar 1:05 pm - Discussion 1:10 pm - Aortic Stenosis and CAD (Simple and Complex) with Case Examples: AVR-CABG vs. TAVR-PCI and When Not to Treat CAD James B. Hermiller Jr 1:20 pm - Discussion Session V. TAVR Evidence-Based Medicine Corner: Consensus, Gaps, and Controversies Moderators: Jeffrey J. Popma, John G. Webb Discussants: Antonio Colombo, Helene Eltchaninoff, Jean-Claude Laborde, Rudiger Lange, Ian T. Meredith, John L. Petersen, Josep Rodes-Cabau, Stefan Sack, Nicolas van Mieghem, Thomas Walther, Olaf Wendler 1:25 pm - Updates from the Pooled Analysis from Multicenter Country TAVR Registries Nicolas van Mieghem 1:35 pm - SOURCE 1, 2, and XT Registries: Take-Home Messages and Late Follow-up Olaf Wendler The World’s Premier Interventional Experience TCT2011 2:05 pm - The Australia-New Zealand Multicenter TAVR Registry Experience Ian T. Meredith 2:15 pm - The Munich Heart Center TAVR Registry: Multiple Devices and Evolving Trends Rudiger Lange 2:25 pm - Updates from the German Aortic Valve Therapy Registry Stefan Sack 2:35 pm - Milan Experiences with Multiple TAVR Systems: Patient and Lesion Profiling Antonio Colombo 2:45 pm - Panel Discussion: Take-Home Messages from the Registry Data Transapical vs. Transfemoral TAVR: A Spirited Debate 3:00 pm - Outcome Differences Are Largely a Reflection of Underlying Patient Characteristics! Thomas Walther 3:10 pm - Outcome Differences Are Determined by Fundamental Procedural Differences and Not Just Patient Characteristics! Jeffrey W. Moses 3:20 pm - Discussion 3:25 pm - Settled and Unsettled PARTNER Issues: A Critical Analysis of the Data Susheel Kodali 3:35 pm - Discussion 3:38 pm - Updates from the US CoreValve Pivotal Randomized Trial Jeffrey J. Popma 3:48 pm - Discussion New Clinical Indications for TAVR 3:51 pm - Balloon Expandable Sapien TAVR: Valve-in-Valve, Bicuspid Disease, and with Mitral Prostheses John G. Webb 4:01 pm - Self-Expanding CoreValve TAVR: Valve-in-Valve, Bicuspid Disease, and Aortic Regurgitation Jean-Claude Laborde 5:55 pm - Discussion Intermediate Risk Patients: Updates from. . . . . Session VII. TAVR Complications: A “No-Holds Barred” Appraisal Moderators: Nicolo Piazza, Josep Rodes-Cabau Discussants: Philippe Genereux, Linda D. Gillam, D. Craig Miller, John G. Webb 4:16 pm - PARTNER 2 Martin B. Leon 4:21 pm - SURTAVI Patrick W. Serruys 4:26 pm - Discussion Session VI. TAVR Procedural Considerations: Screening, Access, Techniques, and Adjunctive Technologies Moderators: Raj Makkar, E. Murat Tuzcu Discussants: Lutz Buellesfeld, Alain G. Cribier, Mirko Doss, Eberhard Grube, Rebecca Tung Hahn, Susheel Kodali, Jean-Claude Laborde, Jonathon A. Leipsic, Augusto D. Pichard, Michael J. Reardon Advanced Imaging 4:30 pm - An Overview of Advanced Imaging Modalities for TAVR Screening and Procedures Lutz Buellesfeld 4:40 pm - Echo Before and During TAVR: A Screening Tool and for Intraprocedural Decision-Making Rebecca Tung Hahn 4:50 pm - CTA Is Indispensable for TAVR Screening and Procedure Planning: What Every Interventionalist and Surgeon Should Know Jonathon A. Leipsic 5:00 pm - Discussion TAVR Access Alternatives and Closure 5:05 pm - Subclavian/Axillary Access (And Results) Jean-Claude Laborde 5:13 pm - Transaortic Options Michael J. Reardon 5:21 pm - Percutaneous Closure Techniques Susheel Kodali 5:29 pm - Discussion The Emerging Minimalist TAVR Approach: Who Needs. . . . 5:35 pm - General Anesthesia? (Monitored Anesthesiology Control Is Better) Augusto D. Pichard 5:40 pm - Transesophageal Echo? (Transthoracic Echo Is Sufficient) Alain G. Cribier 6:00 pm - Strokes May Be the Achilles’ Heel of TAVR! D. Craig Miller 6:10 pm - The Stroke-TAVR Controversy Has Been Exaggerated and Will Be Solved in the Future! John G. Webb - N o v e m b e r 7 , 2 0 11 1:55 pm - The France Multicenter TAVR Registry Experience Helene Eltchaninoff 4:11 pm - Discussion monday 1:45 pm - Canadian TAVR Experiences: Focus on Procedural Complications, Late Clinical Outcomes, and Echo Core Lab Findings Josep Rodes-Cabau T r a n s c at h e t e r Cardiovascular Therapeutics 6:20 pm - Discussion 6:25 pm - Conduction Abnormalities After TAVR: Frequency, Predictors, and Clinical Relevance Nicolo Piazza 6:35 pm - Vascular and Bleeding Events Associated with TAVR: Insights from PARTNER and Future Expectations Philippe Genereux 6:45 pm - Paravalvular Regurgitation: Accurate Diagnosis and Clinical Implications Linda D. Gillam 6:55 pm - Discussion 7:00 pm - Adjourn PFO and ASD Closure: Evolving Indications, Patient Selection, Devices, and Technique 1:00 pm-6:10 Room 130 pm Session I. Update on PFO Stroke Trials Moderators: Ziyad M. Hijazi, Bernhard Meier Discussants: John D. Carroll, Ted Feldman, Mark Reisman, Jeffrey Saver, David E. Thaler 1:00 pm - How to Evaluate Patients with Cryptogenic Stroke David E. Thaler 1:10 pm - PFO Closure for Stroke Prevention: Meta-analysis Evidence from Nonrandomized Trials Jeffrey Saver 1:20 pm - In-depth Review and Failure Analysis of CLOSURE I Mark Reisman Flash Debate: Should We Stop Closing PFOs After CLOSURE I? 5:45 pm - Pretreatment with BAV? (Better Results with “Direct” TAVR) Eberhard Grube 1:30 pm - Pro: With Rare Exception—Primum Non Nocere! Stephen J.D. Brecker 5:50 pm - On-site Surgical Backup? (May Not Be Necessary?) Mirko Doss 1:38 pm - Con: We Certainly Should Continue Closing PFOs! Ted Feldman www.tctconference.com 53 MOnday, November 7 1:46 pm - The RESPECT Trial: Baseline Characteristics and Early Insights John D. Carroll 4:31 pm - The Next Generation of PFO Closure Devices: Problems Solved and Unsolved Horst Sievert 1:56 pm - Discussion with Audience Q&A 4:43 pm - Discussion with Audience Q&A Session II. PFO and Migraine Moderators: Mark Reisman, Horst Sievert Discussants: John D. Carroll, Peter J. Goadsby, Jonathan M. Tobis Session V. ASDs in Adult Patients Moderators: Frank F. Ing, Eustaquio Maria Onorato Discussants: Ziyad M. Hijazi, Eric Horlick, Thomas K. Jones, Horst Sievert 2:11 pm - How Could a PFO Possibly Cause Headache? Peter J. Goadsby 2:21 pm - A Tale of Two PFO Migraine Patients: A Great Success and a Complete Failure Jonathan M. Tobis 2:31 pm - Status of PFO Migraine Clinical Trials: Completed and Ongoing Peter J. Goadsby 2:41 pm - When to Consider Closing PFOs in Migraine Patients TODAY (If Ever) John D. Carroll 2:51 pm - Discussion with Audience Q&A Session III. PFO Closure Beyond Stroke and Migraine Moderators: Michael J. Mullen, Robert J. Sommer Discussants: Paul H. Kramer, Bernhard Meier, John F. Rhodes, Kevin Walsh 3:01 pm - The Truth About PFO and Divers Kevin Walsh 4:53 pm - Indications for ASD Closure and Long-term Outcomes Ziyad M. Hijazi 5:05 pm - REPERA: A Multicenter Registry Examining the Acute and Late Outcomes Following Percutaneous Repair of Large Atrial Septal Defects Felipe Hernandez 5:15 pm - Case 1: Closure of Multiple ASDs Eric Horlick 5:25 pm - Case 2: Closure of a Large ASD with Aneurysm Eustaquio Maria Onorato 5:35 pm - Case 3: Closure of an ASD in an Elderly Patient with a Stiff Ventricle Thomas K. Jones 5:45 pm - Novel Emerging ASD Devices: What Benefits Can We Expect? Horst Sievert 5:55 pm - Discussion with Audience Q&A 6:10 pm - Adjourn 3:11 pm - PFO, Sleep Apnea, and Hypoxemia John F. Rhodes 3:21 pm - PFO, DVT, and Thrombogenic Disorders Paul H. Kramer 3:31 pm - Long-term Outcomes of PFO Closure Bernhard Meier 3:41 pm - Discussion with Audience Q&A Session IV. Difficult Cases, Troubleshooting Moderators: John D. Carroll, John F. Rhodes Discussants: Clifford J. Kavinsky, Michael J. Mullen, Mark Reisman, Horst Sievert, Robert J. Sommer 3:51 pm - Case 1: A Patient with a Questionable Indication Robert J. Sommer 4:01 pm - Case 2: Device Embolization Michael J. Mullen 4:11 pm - Case 3: Thrombus on the Device Clifford J. Kavinsky 4:21 pm - Case 4: Residual Shunt: Assessment and Management Mark Reisman 54 program · Special Twilight Sessions Featured Clinical Research I. Transcatheter Valve and STEMI/Heart Failure Therapies 6:00 pm-8:00 pm Room 121 Moderators: Jeffrey J. Popma, Martyn R. Thomas Discussants: Maurice Buchbinder, Daniel Burkhoff, Charles J. Davidson, Larry S. Dean, Ted Feldman, Olaf Franzen, Thierry Lefevre, Ganesh Manoharan 6:00 pm - UK TAVI: A Large-Scale National Registry Comparing Transcatheter Aortic Valve Type and Access Route Daniel J. Blackman 6:10 pm - Discussion with Audience Q&A 6:15 pm - CoreValve Subclavian: A SingleCenter, Propensity-Case-Controlled Registry of Transcatheter Aortic Valve Implantation via Subclavian vs. Transfemoral Access Anna Sonia Petronio T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 6:25 pm - Discussion with Audience Q&A 6:30 pm - ACURATE TA: A Prospective Observational Study of a New SelfExpanding Transapical Bioprosthesis in Elderly High-Risk Patients with Aortic Stenosis Joerg Kempfert 6:40 pm - Discussion with Audience Q&A 6:45 pm - SAT-TAVI: A Prospective, Randomized Trial of Single vs. Dual Antiplatelet Therapy After Transcatheter Aortic Valve Replacement in High-Risk Patients with Aortic Stenosis Eugenio Stabile 6:55 pm - Discussion with Audience Q&A 7:00 pm - A Two-Center Registry Study Comparing Bivalirudin and Unfractionated Heparin in Patients Undergoing Balloon Aortic Valvuloplasty George D. Dangas 7:10 pm - Discussion with Audience Q&A 7:15 pm - C-PULSE. A Prospective, First-in-Man Study with a Non-Blood Contacting Extra-Aortic Counterpulsation System in Patients with Moderate to Severe Ambulatory Heart Failure William T. Abraham 7:25 pm - Discussion with Audience Q&A 7:30 pm - A Prospective, Randomized Trial of Thrombus Aspiration in Patients with ST-Segment Elevation Myocardial Infarction Assessed by Optical Coherence Tomography Patrick W. Serruys 7:40 pm - Discussion with Audience Q&A 7:45 pm - A Prospective, Multicenter, Randomized Trial of Zotarolimus-Eluting Stents and Sirolimus-Eluting Stents in Patients with ST-Segment Elevation Myocardial Infarction Lefeng Wang 7:55 pm - Discussion with Audience Q&A 8:00 pm - Adjourn New Patients for New Interventional Therapies 6:00 pm-7:15 pm Room 122 Moderators: Saibal Kar, Horst Sievert Discussants: Tony Das, Manish A. Parikh, Robert J. Whitbourn 6:00 pm - Maintaining a Robust Coronary Referral Practice in the Modern Era Manish A. Parikh The World’s Premier Interventional Experience TCT2011 7:45 pm - Discussion with Audience Q&A 6:15 pm - Growing a Thriving Endovascular Referral Base: Outreach Programs and Opportunities Tony Das 8:00 pm - Adjourn 6:25 pm - Discussion with Audience Q&A 7:00 Evening Programs - N o v e m b e r 7 , 2 0 11 Creating New Referral Sources for New Interventional Programs: Structural, Valve, Adult Congenital, and Hypertension monday 6:10 pm - Discussion with Audience Q&A T r a n s c at h e t e r Cardiovascular Therapeutics pm -10:00 pm Please see page 146 for the Evening Programs schedule 6:30 pm - A European Success Model Horst Sievert 6:40 pm - US Approaches Saibal Kar 6:50 pm - Strategies from “Down Under” Robert J. Whitbourn 7:00 pm - Discussion with Audience Q&A 7:15 pm - Adjourn Partnership Session: Angioplasty Summit-TCTAP 6:00 pm-8:00 Room 120 pm Left Main and Bifurcation Stenting: Optimization with FFR and IVUS Moderators: Gary S. Mintz, Seung-Jung Park, Gregg W. Stone Discussants: Antonio Colombo, David J. Hildick-Smith, Soo-Jin Kang, Young-Hak Kim, Akiko Maehara, Raj Makkar, Jeffrey W. Moses, Patrick W. Serruys 6:00 pm - Welcome and Introductory Remarks Seung-Jung Park 6:03 pm - Morphology and Distribution of Left Main and Non-Left Main Bifurcation Atherosclerosis: Why Is This Important? Akiko Maehara 6:13 pm - Discussion with Audience Q&A 6:16 pm - IVUS and FFR to Guide Non-Left Main Bifurcation PCI Soo-Jin Kang 6:31 pm - Discussion with Audience Q&A 6:38 pm - Two Complex Non-Left Main Bifurcation Cases: My Solutions David J. Hildick-Smith 6:53 pm - IVUS and FFR to Guide Left Main Bifurcation PCI Seung-Jung Park 7:08 pm - Discussion with Audience Q&A 7:15 pm - Two Distal Left Main Bifurcation Cases: My Solutions Jeffrey W. Moses 7:30 pm - Two Distal Left Main Trifurcation Cases: My Solutions Antonio Colombo www.tctconference.com 55 TCTMD The source for interventional cardiovascular news and education Become a member of TCTMD GOLD at www.tctmd.com/GOLD Get the most out of TCTMD with TCTMD Gold! Get the most out of TCTMD with TCTMD Gold! Subscribe to TCTMD Gold for access to: • M orethan8,000PowerPointandmultimedia web cast presentations from: - TCT 2011 - Transcatheter Valve Therapies 2011 - OptimizingPCIOutcomes2011 - InterventionalCardiologyFellowsCourse2011 - InternationalChronicTotalOcclusionSummit2011 - TCT 2010 - S electpresentationsarealsoavailablefrom ACC2011,PCR2011andESC2011 • Morethan300livecasevideosfrom: - TCT 2011, TCT 2010, TCT 2009 - TVT 2011, TVT 2010 - CTO 2011 Additional premium content will be available throughout the year. Visit www.tctmd.com/GOLD to register! For more information, visit www.tctmd.com/GOLD or contact Josh Hartman, Managing Editor, TCTMD, at 646-434-4604 or [email protected]. The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Board Review Course with Self-Assessment in Interventional Cardiology (Part 2)......................................... 58 TCT for Nurses and Technologists . . ..................................58, 59 TCT for Surgeons...................................................................59, 93 Scientific Symposia Surgical, Interventional, and Hybrid Procedures (Part 1): Coronary Revascularization ....................................................................... 59 Peer-Reviewed Research Poster Abstract Sessions .......................................................................... 60 Challenging Cases Video Abstracts........................................................... 79 Oral Abstract Sessions .............................................................................. 82 Scientific Symposia (Continued) Device-Based Approaches for Heart Failure: Recent Developments and New Directions................................................ 88 Endovascular Intervention (Part 2) ............................................................. 89 Hot Topics in Interventional Cardiology: ACC.11 Highlights for the Interventional, Invasive, and General Cardiologist ......................... 89 Next Generation Drug-Eluting Stents and Bioabsorbable Scaffolds........... 92 The Valvular Heart Disease Summit (Part 2): Mitral Valve Therapies........... 93 Translational Research and First-in-Human Studies for Emerging Cardiovascular Technologies................................................ 93 Transradial Angiography and Intervention: From Basic to Advanced ........ 94 Japan-US Synergies for Medical Device Innovation: A Harmonization by Doing (HBD) Educational Symposium.........................95 Presentation Theater South.......................................................... 150 Special Twilight Sessions Featured Clinical Research II. Drug-Eluting Stent vs. Stent Studies ......................................................... 96 san francisco, ca SCAI ELM Program in Partnership with ACC and CRF............................... 95 · Special Sessions November 8, 2011 Left Atrial Appendage Closure: Indications, Devices, and Techniques....... 91 the Moscone Center Identifying the High-Risk Patient and Lesion: From Vulnerable Plaque to Ischemia and Viability...................................... 90 Tuesday Breakfast Meetings............................................................................147 How to Treat Complex Lesions.................................................................. 96 Partnership Session: CIT in Partnership with TCT: Challenging Cases in Clinical Practice....................................................... 97 Partnership Session: TCT Russia: Focused Session on Endovascular and Structural Heart Disease............................................... 97 Evening Programs............................................................................. 150 www.tctconference.com 57 Tuesday, November 8 Breakfast Meetings 7:00 am -8:00 am Please see page 147 for the Breakfast Meetings schedule. Board Review Course with Self-Assessment In Interventional Cardiology (Part 2) This session is not CE accredited for nurses. 8:00 am-6:00 Room 103 pm Interventional Cardiology Devices and Outcomes Moderators: Emmanouil S. Brilakis, George D. Dangas 1:00 pm - PCI for Left Main and Multivessel CAD David R. Holmes Jr 1:30 pm - Complex Lesions: Bifurcations and CTO David E. Kandzari 2:00 pm - Thrombectomy and Distal Protection in Native Coronary Artery and Saphenous Vein Graft Lesions Emmanouil S. Brilakis 2:30 pm - Break Cardiac Cath Lab Basics Moderators: Steven R. Bailey, Manish A. Parikh 8:00 am - Coronary Angiography and Ventriculography: Anatomy and Anomalies Michael J. Lim 8:30 am - Chronic Kidney Disease, Contrast Agents, and Radiocontrast Nephropathy Roxana Mehran 8:50 am - Selection of Angioplasty Guiding Catheters, Wires, and Balloons Aaron D. Kugelmass 9:10 am - Angioplasty, Atherotomy, and Atherectomy: Mechanisms of Action, Results, and Current Indications Steven R. Bailey Special Interventional Imaging and Physiology Session Moderators: Massoud A. Leesar, Gary S. Mintz 3:00 pm - Physiologic Lesion Assessment Guidelines, Key Clinical Results, and Case Presentations (with Integrated Q&A) Michael J. Lim Stents Moderators: George D. Dangas, Ajay J. Kirtane 10:00 am - Bare Metal vs. Drug-Eluting Stents: Mechanisms of Action, Results, and Comparative Effectiveness Ajay J. Kirtane 10:30 am - Drug-Eluting Stent Systems and Results Duane S. Pinto 11:00 am - In-Stent Restenosis: Mechanisms, Predictors, and Treatment Roxana Mehran Breakout Symposium I. The Great Debates 8:00 am-12:00 Room 102 pm Topic I. The Status of PFO Closure After CLOSURE 1 Moderator: Russell A. Brandwein 8:00 am - Understanding PFO Russell A. Brandwein 8:12 am - PFO Closure Is No Longer Indicated! Brad I. Munt 8:24 am - PFO Closure Still Has Its Place! Jonathan M. Tobis 8:36 am - Rebuttals and Discussion Topic II. Treatment of Carotid Artery Disease Moderator: Russell A. Brandwein 8:48 am - Carotid Artery Disease Essentials Pilar Dolcimascolo 3:45 pm - Intravascular Ultrasound Guidelines, Key Clinical Results, and Case Examples (with Integrated Q&A) Gary S. Mintz 9:00 am - CEA Is the Way! Michael J. Reardon Essentials of Vascular Disease 9:24 am - Rebuttals and Discussion Moderators: Prakash Krishnan, Jeffrey W. Olin Topic III: Vascular Access Moderator: Russell A. Brandwein 4:30 pm - Endovascular Rescue During Cardiac Interventions Prakash Krishnan 9:30 am - Break TCT for Nurses and Technologists 5:00 pm - Essentials of Aortic and Peripheral Arterial (Upper/Lower Extremity) Diseases: Guidelines, Assessment, and Outcomes Jeffrey W. Olin 5:30 pm - Essentials of Carotid Artery Diseases: Guidelines, Assessment, and Outcomes Jose M. Wiley 5:45 pm - Essentials of Renal Artery Disease: Guidelines, Assessment, and Outcomes Jeffrey W. Olin 6:00 pm - Adjourn 11:30 am - Stent Thrombosis: Mechanisms, Predictors, and Treatment George D. Dangas 12:00 am - Lunch Break 9:12 am - PTA Is the Way! Herbert D. Aronow 9:36 am - Vascular Anatomy 101 Sheehan L. Raab 9:48 am - Radial Access for All! Martial Hamon 10:00 am - Femoral Is Still No. 1! Jeffrey W. Moses 10:12 am - Rebuttals and Discussion Topic IV. Lesion Assessment in the Cath Lab Moderator: Russell A. Brandwein 10:24 am - Lesion Assessment Beyond Angiography Caesar Alvero 10:36 am - IVUS Is All You Need! Michael J. Rinaldi 10:48 am - FFR Wins by Far! Pim A.L. Tonino 11:00 am - Rebuttals and Discussion Topic V. Left Main Disease Moderator: Russell A. Brandwein 11:12 am - Left Main Disease Review Sarah Clarke 58 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 11:36 am - Left Main Disease Equals PCI! Paul S. Teirstein 12:00 pm - Adjourn Breakout Symposium II. Working in Today’s Cath Lab 8:00 am-12:00 Room 134 pm 8:00 am - Introduction and Session Objectives Trends in Professional Practice Moderator: Janet F. Wyman Discussants: Marian C. Hawkey, Christopher M. Nelson 8:05 am - Maintaining Staff Proficiency with Professional Certification and Competencies Christopher M. Nelson 8:20 am - Role of Midlevel Practitioners Janet F. Wyman 8:35 am - Integrating Clinical Research into the Cath Lab Marian C. Hawkey 8:50 am - Discussion with Audience Q&A Trends in Patient Management Moderator: Thomas H. Maloney Discussants: Jacqueline Kixmiller, Michael Querijero 9:00 am - Adapting to the Needs of Our Diverse Patient Population Michael Querijero 9:15 am - Adapting to New Techniques and Technology Thomas H. Maloney 9:35 am - Adapting to the Challenges of the 23-Hour Admission Jacqueline Kixmiller 9:50 am - Discussion with Audience Q&A Spotlight Session: TAVR Program Development and Clinical Management Discussants: Sarah Clarke, Marian C. Hawkey, Martina Kelly Speight, Sandra Lauck 10:00 am - Moving Parts: Who and What Do You Need? Marian C. Hawkey 10:15 am - Managing Referral Volume Sarah Clarke 10:30 am - Matching Patients to Treatment Options Martina Kelly Speight 10:45 am - Recommendations for Clinical Management Sandra Lauck 11:15 am - Austria Lynne Hinterbuchner 11:20 am - New Zealand Rhona MacDonald 11:25 am - Qatar Elsayed Mahmoud 11:30 am - Spain Siro Buendia 11:35 am - Discussion with Audience Q&A 11:50 am - Final Comments and Wrap-up 12:00 pm - Adjourn Breakout Symposium III. Business Development and Operations 8:00 am-12:00 pm Room 135 Moderators: Michael Guiry, Hilary Nierenberg 8:00 am - Health Care Reform: A Climate Overview James M. Palazzo 8:25 am - What Is Happening with Fee for Service? James M. Palazzo 8:38 am - Cardiology Practice Acquisitions: How Will This Impact Your Volume? Robert R. Moss 8:50 am - Cardiovascular Practice Trends Michael Guiry 9:00 am - Discussion with Audience Q&A 9:12 am - The Cardiovascular Service Line Physician Growth Strategies Ellen Komar 9:24 am - Drivers of Patient Satisfaction to Improve Market Share Patricia M. Pye 9:36 am - Effectively Branding and Marketing Your Cardiovascular Program Dan Polcyn 10:24 am - RAC Protection Program: Successful Documentation to Maintain Revenue Glenna Friedman 10:36 am - Cloud Technology and Patient Education Rob Dhoble 11:00 am - Discussion with Audience Q&A 11:12 am - Staffing Competencies for Hybrid Rooms: Nightmare or Nirvana? Anthony Dawson 11:24 am - Is That a Cardiac Surgeon in My Cath Lab? Mathew Williams - N o v e m b e r 8 , 2 0 11 11:48 am - Rebuttals and Discussion International Perspectives on Working in the Cath Lab Moderator: Regina Deible Discussants: Siro Buendia, Lynne Hinterbuchner, Sumaira Macdonald, Elsayed Mahmoud Tuesday 11:24 am - Left Main Disease Equals CABG! Mark W. Connolly T r a n s c at h e t e r Cardiovascular Therapeutics 11:36 am - Cardiovascular Programs of the 21st Century Charanjit S. Rihal 11:48 am - Discussion with Audience Q&A 12:00 pm - Adjourn SciEntific Symposia Surgical, Interventional, and Hybrid Procedures (Part 1): Coronary Revascularization Co-sponsored by the American Association for Thoracic Surgery This session is not CE accredited for nurses. 8:00 am-12:00 Room 133 pm Session I. Evolution of Coronary Revascularization Moderators: William E. Cohn, A. Marc Gillinov Discussants: Johannes Bonatti, Robert A. Guyton, Martin B. Leon, Friedrich W. Mohr, Marie-Claude Morice, Jeffrey W. Moses, Joseph F. Sabik, Gregg W. Stone, Paul S. Teirstein 8:00 am - PCI Technique and Technology: Evolution from the Past to the Present with Prediction for the Future Martin B. Leon 9:48 am - Discussion with Audience Q&A 8:12 am - CABG Technique and Technology: Evolution of a Subspecialty—And Are Most Surgeons Adapting? Johannes Bonatti 10:00 am - Cath Lab Quality Reporting: Appropriate Use Criteria and What It Means Judy Tingley 8:24 am - Chair’s Informal Comments: On the Evolution of Coronary Revascularization William E. Cohn, A. Marc Gillinov 10:12 am - Successful Practices Leave Nothing Behind Rona G. Kahn 11:00 am - Discussion with Audience Q&A www.tctconference.com 59 Tuesday, November 8 Session II. Multivessel Disease Moderators: Robert A. Guyton, Paul S. Teirstein Discussants: Johannes Bonatti, William E. Cohn, A. Marc Gillinov, Martin B. Leon, Friedrich W. Mohr, Jeffrey W. Moses, Joseph F. Sabik, Gregg W. Stone 8:29 am - PCI Today: Best Practices, Optimal Outcomes, and Limitations: When Do I Prefer CABG for MVD? Gregg W. Stone 8:41 am - CABG Today: Best Practices, Optimal Outcomes, and Limitations: When Do I Prefer PCI for MVD? Joseph F. Sabik Should the Syntax Score Guide Therapy in MVD? 8:53 am - Yes: The Data Are Clear! Friedrich W. Mohr 9:03 am - No: The Syntax Score Is Too Simplistic! Jeffrey W. Moses 9:13 am - Discussion with Audience Q&A Moderators: Robert A. Guyton, Marie-Claude Morice Session III. Left Main Disease Moderators: A. Pieter Kappetein, Patrick W. Serruys Discussants: Vladimir Dzavik, Marie-Claude Morice, David Taggart Is PCI Appropriate for Up to 50% of Patients with Left Main Disease? 9:23 am - Yes: Today and Tomorrow! Marie-Claude Morice 9:33 am - Based on Today’s Evidence, Most Patients with Left Main Disease Should Go to the OR! David Taggart 9:43 am - Ventricular Support for Unprotected Left Main (and Other High-Risk PCI Scenarios): Options and Indications (Routine vs. Provisional) Vladimir Dzavik 9:53 am - Discussion with Audience Q&A Session IV. Hybrid Treatment of Coronary Artery Disease Moderators: Johannes Bonatti, David Zimrin Discussants: Michael J. Davidson, Joseph J. DeRose, John D. Puskas, Corrado Tamburino, Vinod H. Thourani 10:03 am - Rationale for Hybrid Revascularization: The Best of Both Worlds? Johannes Bonatti 60 program · 10:13 am - Hybrid Revascularization: Who Goes First? Joseph J. DeRose 10:23 am - Antiplatelet Therapy for Hybrid Revascularization David Zimrin 10:33 am - The NIH Trial on Hybrid Revascularization: Rationale, Design, and Status Update John D. Puskas 10:43 am - Concurrent Coronary Artery and Valvular Heart Disease 1: Hybrid PCI with Surgical Valves Vinod H. Thourani 10:53 am - Concurrent Coronary Artery and Valvular Heart Disease 2: Hybrid PCI with Transcatheter Valves Corrado Tamburino 11:03 am - The Hybrid Room: What Is It, and Is It Necessary? Michael J. Davidson 11:13 am - Discussion with Audience Q&A Session V. CAD Case Presentations: CABG, PCI, Hybrid, or Medical Therapy? (Multidisciplinary Panel) Moderators: Johannes Bonatti, Mathew Williams Discussants: William E. Boden, Joseph J. DeRose, William F. Fearon, Gregory P. Fontana, Isaac George, Jeffrey W. Moses, Robert S. Poston, John D. Puskas, Robaayah Zambahari, David Zimrin 11:25 am - Three Cases of Increasing Patient and Anatomic Complexity Isaac George 12:00 pm - Adjourn Adjunct Pharmacology TCT-150. Genetic Variants Affecting Clopidogrel Metabolism Have Minor Influence on Platelet Reactivity After Elective Percutaneous Coronary Intervention Andras Komocsi et al TCT-151. Paraoxonase-1 (PON1) Activity and PON1 Polymorphisms Have No Effect on Platelet Reactivity in Patients Treated with Clopidogrel Jean-Pierre P. Dery et al TCT-152. Pharmacodynamic Effect of Double-Dose Clopidogrel vs. Adding Dipyridamole In Patients with High On-Treatment Platelet Reactivity (ACCEL-DIP) Study Yongwhi Park et al TCT-153. CYP3A4 Genetic Status May Be Associated with Increased Vulnerability to the Adverse Effect of Calcium Channel Blockers on Clopidogrel Response Variability Jin Joo Park et al TCT-154. Stopping Clopidogrel One-Year After Drug-Eluting Stent (DES) Implantation: Is It Safe? Nalyaka Sambu et al TCT-155. Genetic Determinants of Clopidogrel Responsiveness in Koreans Jin Joo Park et al TCT-156. Safety of Dual Antiplatelet Therapy in Patients Treated with Coronary DrugEluting Stents Andrzej Drewnicki et al TCT-157. Methods of Measurement of Aspirin-Mediated Antiplatelet: Degree of Correlation and Agreement Between Two Point of Care: VerifyNow Aspirin Assay and PFA-100 Jose Maria Cubero Gomez et al Poster Abstract Sessions and Challenging Cases Video Abstracts TCT-158. Inhibition of Platelet Aggregation by Prostaglandin E1 (PGE1) May Be Attenuated in Diabetic Patients During Therapy with Clopidogrel Rolf P. Kreutz et al 8:00 am-10:00 am Hall D See page 166 for the poster abstracts map. TCT-159. Recovery of Platelet Function After a Loading Dose of Prasugrel or Clopidogrel in Patients with Coronary Artery Disease Isabell Bernlochner et al Poster Session Moderators: Michael J. Cowley, Raimund A. Erbel, James R. Margolis, E. Magnus Ohman Poster Session Discussants: Andrea Abizaid, Vinay K. Bahl, Daniel H. Berrocal, Graham A. Cassel, Leslie Cho, Roberto Corti, David Erlinge, Marc D. Feldman, Ioannis Iakovou, Henning Kelbaek, Carey D. Kimmelstiel, Gervasio A. Lamas, Guy LeClerc, Pedro A. Lemos, Norman E. Lepor, Massimo Napodano, Pedro R. Moreno, Juan C. Parodi, Frederic S. Rensic, Peter H. Stone T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s TCT-160. High On-Treatment Platelet Reactivity Measured by Various Platelet Function Tests: Is the Current VASP-PRI Cutoff Too Low? Young-Hoon Jeong et al TCT-161. Anemia Is a Major Predictor of Decreased Platelet Response to Clopidogrel Following Coronary Stenting Catalin Toma et al The World’s Premier Interventional Experience TCT2011 TCT-164. Impact of Bleedings on Prasugrel Adherence in Real-World Patients Guido Parodi et al TCT-165. Response to Prasugrel in ST-Elevation Myocardial Infarction Patients: Is It as Rapid as We Expected? Frédéric Casassus et al TCT-166. Clinical Outcomes of Intracoronary Eptifibatide Bolus-Only vs. Intracoronary Bolus and Intravenous Infusion of Eptifibatide in Primary Percutaneous Coronary Intervention Dinna K. Soon et al TCT-167. Protease Activated Receptor-1 (PAR-1) Mediated Platelet Aggregation Is Dependant on Clopidogrel Response Rolf P. Kreutz et al TCT-168. Adherence to Evidence-Based Medical Therapy According to Management Strategy in Patients with Acute Coronary Syndrome Samer Mansour et al TCT-169. Safety and Efficacy for the Use of Prasugrel in Patients Undergoing Percutaneous Coronary Intervention and Anticoagulated with Bivalirudin Ana Laynez et al TCT-170. Additive Pharmacodynamic Effects of Double-Dose Clopidogrel According to CYP2C19*2 vs. *3 Variant Young-Hoon Jeong et al TCT-171. Cytochrome P450 2C19 Loss-of-Function Genetic Variants but Not Paraoxonase-1 Activity Modulate P2Y12 Blockade in Response to Clopidogrel Therapy Arun Karunakaran et al TCT-172. Long-term Dual Antiplatelet Therapy in Patients Treated with Bare Metal Stent Implantation: Results from the NHLBI Dynamic Registry Gopi Manthripragada et al TCT-174. Low-Molecular-Weight Heparins vs. Unfractionated Heparin in the Setting of Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction: A Meta-analysis Eliano P. Navarese et al TCT-175. Evaluation of Dose Requirements for Prolonged Bivalirudin Administration in Patients with Renal Insufficiency and Suspected Heparin-Induced Thrombocytopenia James W. Wisler et al TCT-176. Access and Non-Access Site Bleeding in Acute Coronary Syndrome Patients Treated with a Novel Actively Reversible Factor IXa Inhibitor: Results from the RADAR Trial Mauricio G. Cohen et al TCT-177. In-Hospital and 30-Day Outcomes in All-Comer Percutaneous Coronary Intervention with Bivalirudin: Initial Report of the Prospective EUROVISION Registry Martial Hamon et al TCT-178. Use of the REG1 Anticoagulation System During PCI May Improve Bleeding and Ischemic Complications Compared with Heparin: A PCI Substudy from the Phase 2B RADAR Trial Thomas J. Povsic et al TCT-179. Efficacy and Safety of Bivalirudin Compared to Unfractionated Heparin in Relation to the Use of “Preclose” Technique Using the Perclose Vascular Closure Device Among Patients Undergoing Balloon Aortic Valvuloplasty Shyam Poludasu et al TCT-180. Patients with Acute Coronary Syndrome Have Higher Levels of OnTreatment Platelet Reactivity Michael A. Gaglia et al TCT-181. Benefits of CD34 Antibody-Coated Stent in Patients with High Risk for Bleeding During Dual Antiplatelet Therapy Miltiadis Papalexandris et al TCT-182. On-Treatment Platelet Reactivity Before Coronary Artery Bypass Surgery Is Associated with In-Hospital Major Bleeding: Results of a Prospective Evaluation Gabriel L. Sardi et al TCT-183. The Impact of Paraoxonase-1 Activity on the Incidence of Intrastent Thrombus After Drug-Eluting Stent Implantation in the Japanese CYP2C19*2 Carriers Receiving Clopidogrel Ryo Nishio et al TCT-184. Immobilized Recombinant Human Tropoelastin on a Plasma-Activated Coating Dramatically Enhances Biocompatibility of Metal Alloys: Implications for Coronary Stents Martin Ng et al TCT-185. Comparison of Bivalirudin vs. Heparin During PCI in Patients Receiving Prasugrel Martial Hamon et al - N o v e m b e r 8 , 2 0 11 TCT-163. Accelerated Platelet Inhibition After Switching with Hydrophilic Statin in Patients with Increased Platelet Reactivity During Atorvastatin and Clopidogrel Coadministration (ACCEL-STATIN) Study: A Randomized, Parallel-Group Trial Young-Hoon Jeong et al TCT-173. The Association Between Duration of Clopidogrel Therapy After Saphenous Vein Graft Intervention and Long-term Death and Myocardial Infarction Amit Sachdeva et al Tuesday TCT-162. Ticagrelor Enhances Adenosineinduced Coronary Vasodilatory Responses in Humans: Randomized, Double-Blind, Placebo-Controlled, Crossover, SingleCenter Study Using Transthoracic Color Doppler Echocardiography Li-Ming Gan et al T r a n s c at h e t e r Cardiovascular Therapeutics TCT-186. Combination Abciximab and tPA Use with the Trellis-6 Peripheral Infusion System for Thrombotic Occlusion of the Superficial Femoral and Popliteal Arteries Eric J. Dippel et al TCT-187. The Utility and Safety of Bilivalirudin in Out-Patient Peripheral Procedures R. Stefan Kiesz et al TCT-188. Long-term Outcomes in Patients with Acetylsalicylic Acid Sensitivity Undergoing a Novel Desensitization Protocol Roberta Rossini et al Bioabsorbable, Drug-Eluting, and Bare Metal Stent Studies TCT-192. Two-Year Patient Outcomes with the Resolute Zotarolimus-Eluting Stent: Results of the RESOLUTE International Registry Jorge Belardi et al TCT-193. Outcomes After Revascularization with Everolimus- and Sirolimus-Eluting Stents In Patients with Acute Coronary Syndromes: A Substudy of the SORT OUT IV Trial Lisbeth Antonsen et al TCT-194. Off-Label Use of Drug-Eluting Stent with Biodegradable Polymer at Two Years Gian Battista Danzi et al TCT-195. Current Treatment and Outcome of Coronary In-Stent Restenosis: Report from the Swedish Angiography and Angioplasty Registry (SCAAR) Torsten Schwalm et al TCT-196. Restenosis Pattern of Drug-Eluting Stent: Impact of Stent Type and Timing Noriyuki Ohashi et al www.tctconference.com 61 Tuesday, November 8 TCT-197. Multicenter, Prospective, Randomized, Single-Blind, Consecutive Enrollment Evaluation of the Elixir DESyne BD Novolimus-Eluting Coronary Stent System with Bioabsorbable Polymer Compared to the Endeavor ZotarolimusEluting Coronary Stent System: Six Months Alexandre Abizaid et al TCT-198. The Impact of XIENCE V: Everolimus-Eluting Coronary Stents on Health Status in COURAGE-Like Patients David R. Rutledge et al TCT-199. ENERGY 1,000-Patient Registry with a Thin Strut Bare Metal Stent with Passive Coating Presenting Six Month Follow-up MACE Raimund Erbel et al TCT-200. DES vs. MIDCAB for Proximal LAD Disease: Long-term Registry Results Piotr P. Buszman et al TCT-201. Incidence of Periprocedural Myocardial Infarction Following Stent Implantation: Comparison Between First and Second Generation Drug-Eluting Stents Kenneth Tandjung et al TCT-202. The Difference of Predictors for Occurrence of Instent Restenosis in the Underexpanded or Non-Underexpanded Post-DES Implantation: An Intravascular Ultrasound Analysis from Multicenter, Randomized Trials Ki-Woon Kang et al TCT-203. No Difference In Long-term Major Adverse Cardiac Event Rates Between Paclitaxel-Eluting and SirolimusEluting Stents James P. Howard et al TCT-204. A Comparative Analysis of Major Clinical Outcomes with Drug-Eluting Stents vs. Bare Metal Stents in Male vs. Female Patients Ran Kornowski et al TCT-205. The Nine-Month Outcomes of a Polymer-Free Drug-Eluting Stent (YUKON) Compared with Different Polymer Based Drug-Eluting Stents in Real-World Coronary Artery Lesions Ted S. Trajceski et al TCT-206. Real-World Comparison of Clinical Outcomes of Patients Who Received New Generation Platinum Chromium EverolimusEluting Stent vs. Cobalt Chromium Everolimus-Eluting Stent Ruogu Li et al TCT-207. Interim Analysis of the IMOS MGUARD International Registry Chaim Lotan et al 62 program · TCT-208. Late Clinical Impact of Postprocedural Incomplete Stent Apposition and Late Acquired Incomplete Stent Apposition After Deployment of ZotarolimusEluting Stent or Everolimus-Eluting Stent Sang-Rok Lee et al TCT-209. Drug-Eluting Stents in the Treatment of Isolated Proximal LAD Disease Are Associated with Similar Outcomes Compared to Minimally Invasive LIMA Grafts Daniel A. Jones et al TCT-210. Low Incidence of Stent Thrombosis in Asian Races: Multicenter Registry in Asia Six-Year Follow-up Results Sunao Nakamura et al TCT-211. The SYNTAX Trial at Three Years: A Global Risk Approach to Identify Patients with Three-Vessel and/or Left Main Stem Disease Who Could Safely and Efficaciously Be Treated with Percutaneous Coronary Intervention (Part 2): The All-Comers SYNTAX Population Vasim Farooq et al TCT-212. Are Results from an All-Comers Registry Comparable with the Results from an All-Comers Randomized Clinical Trial? Insights from 12-Month Results of the e-BioMatrix PMS Registry Philip Urban et al TCT-213. Increased Tissue Stress Leads to Increased Neointima Evaluated by Histology and Computational Modeling Chad Abunassar et al TCT-214. Safety and Effectiveness of Everolimus-Eluting Stents in 5,054 Patients from a Large, Prospective, Real-World Study: Two-Year Clinical Outcomes from the XIENCE VÆ USA Study Mitchell W. Krucoff et al TCT-215. STEALTH I: Five-Year Follow-up from a Prospective, Randomized Study of Biolimus A9-Eluting Stent with a Biodegradable Polymer Coating vs. a Bare Metal Stent Ricardo Costa et al TCT-216. In-Hospital Experience of “Real-World” Patients Enrolled in the TAXUS Liberte Post-Approval Study: The TAXUS Liberte Stent with Concomitant Prasugrel Therapy David P. Lee et al TCT-217. Impact of Total Stent Length per Patient and per Lesion on Five-Year Clinical Outcomes Shirai Shinichi et al TCT-218. New Application of a LongExisting Index Score Philip Urban et al T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s TCT-219. Prospective Evaluation of the Xience V Everolimus-Eluting Stent In Saphenous Vein Graft Atherosclerosis: The Xience V-SVG Angiographic Study Emmanouil S. Brilakis et al TCT-220. Efficacy and Saftey of 38-mm-Long Stent Treatment for Diffuse Coronary Disease: A Multicenter Evaluation by Angiography and OCT Analysis at One Year After Implantation Giuseppe Sangiorgi et al TCT-221. Long-term Safety and Effectiveness of Drug-Eluting Stents Compared to Bare Metal Stents in Non-ST-Elevation Myocardial Infarction: Findings from the Guthrie Health Off-Label STent (GHOST) Registry Sudhakar Sattur et al TCT-222. Everolimus-Eluting Stents Show No Stent Thrombosis with Similar One-Year Outcomes Compared with First and Second Generation Drug-Eluting Stents for the Treatment of ST-Segment Elevation Myocardial Infarction Kyounghoon Lee et al TCT-223. Complete Revascularization and Clinical Outcomes of Patients with Multivessel Disease Jozef Bartunek et al TCT-224. Coating Irreguralities of Drug-Eluting Stents as Assessed by Scanning Electron Microscopy Takeshi Ijichi et al TCT-225. Safety and Efficacy of the Xience Everolimus-Eluting Stent Compared to First-Generation Drug-Eluting Stents in Contemporary Clinical Practice Israel M. Barbash et al TCT-226. Five-Year Survival After Percutaneous Coronary Intervention with Drug-Eluting Stents and Bare Metal Stents in All-Comers: A New Jersey Statewide Database Study Tudor Vagaonescu et al TCT-227. Validation of Age, Creatinine, and Ejection Fraction Score as a Risk Assessment Tool in Patients Undergoing Stent Implantation During Percutaneous Coronary Intervention: A Report from the Dynamic Registry of the National Heart, Lung, and Blood Institute Hiroya Nambu et al TCT-228. Four-Year Follow-up of the SYNTAX Trial: Optimal Revascularization Strategy in Patients with Three-Vessel Disease and/or Left Main Disease David R. Holmes et al The World’s Premier Interventional Experience TCT2011 TCT-231. One-Year Results of the Multicenter, Double-Blinded, Randomized, VESTAsync II Trial Jose De Ribamar Costa et al TCT-232. Impact of Stent Size and Length on Neointimal Hyperplasia After Resolute Zotarolimus-Eluting Stent Implantation: Insights from the RESOLUTE Trials Ryotaro Yamada et al TCT-233. First-in-Man IVUS Findings of the Prohealing PROTEX Coronary Stent System for the Treatment of Coronary Artery Disease Kenji Sakata et al TCT-234. Vascular Healing After Endothelial Progenitor Cell Capturing Stent Implantation at 30 Days Tuomas Lehtinen et al TCT-235. Evaluation of Neointimal Healing of EPC-Capturing Sirolimus-Eluting COMBO Stent by Optical Coherence Tomography: The EGO-COMBO Pilot Study (Interim Results) Stephen W. Lee et al TCT-236. Twelve-Month Clinical Efficacy and Safety of Zotarolimus- vs. Everolimus-Eluting Stents in a Series of Asian Population SunWon Kim et al TCT-237. Two-Year Outcomes of a PropensityMatched Comparison of the ION and TAXUS Liberte Paclitaxel-Eluting Stents Dean J. Kereiakes et al TCT-238. Proximal and Distal Maximal Luminal Diameters (Dmax) as a Guide to Appropriate Deployment of the Everolimus-Eluting Bioresorbable Vascular Scaffold: A Substudy of the ABSORB Cohort B and Ongoing ABSORB EXTEND Single-Arm Study Vasim Farooq et al TCT-239. Final Results of the SVELTE Trial with the Novel Acrobat Balloon-Expandable SOAW Coronary System Jose De Ribamar Costa et al TCT-240. Platinum Chromium EverolimusEluting Stent in Long Coronary Lesions Paul S. Teirstein et al TCT-242. First Report of a Novel Abluminal Groove-Filled Biodegradable Polymer Rapamycin-Eluting Stent in De Novo Coronary Artery Disease: Results of the First-in-Man FIREHAWK Trial Bo Xu et al TCT-243. Six-Month Clinical and Angiographic Results of the BIOSOLVE-I with the Drug-Eluting Absorbable Metal Scaffold Michael Haude et al TCT-244. Bioadhesive, Drug-Impregnated Thin Films for Vascular Restenosis Treatment Terry W. Steele et al TCT-245. ABSORB Cohort B Trial: Two-Year Clinical and Angiographic Results of the ABSORB Bioresorbable Everolimus-Eluting Vascular Scaffold John Ormiston et al TCT-246. Differences in Cardiovascular Risk Factors and Clinical Outcomes Between Western European and Southeast Asian Patients Treated with the EPC Capturing Stent: A Substudy of the e-HEALING Registry Margo Klomp et al TCT-247. Preliminary Data from ABSORB EXTEND: A Report of the Six-Month Clinical Outcomes from the First 200 Patients Enrolled Alexandre Abizaid et al TCT-248. Predictors of Adverse Cardiac Events After PCI with GENOUS EPC-Coated Stents Compared to Drug-Eluting Stents Boris Rudenko et al TCT-249. DESSOLVE I FIH Trial of the MiStent DES: Sirolimus-Eluted from an Absorbable Polymer on a Thin Strut Stent Is Highly Efficacious John Ormiston et al TCT-250. An All-Comers Randomized Trial Comparing Xience Prime and Promus Element Stents: Preliminary Results Jose M. De la Torre Hernandez et al TCT-251. Comparison of Polymer-Free BioFreedom Stents with Durable Polymer Taxus Liberte Stents: Two-Year Results from the BioFreedom First-in-Man Trial Eberhard Grube et al TCT-252. Proof-of-Concept Experience with the Acrobat Svelte Stent-on-a-Wire System in Complex Coronary Interventions: A Multicenter European Pilot Study, the “PEACE” Study Ahmed Rezq et al TCT-253. Long-term Luminal Change After Drug-Eluting Stent Implantation: Serial Angiographic Follow-up Study of the ZEST Randomized Trial Gyung-Min Park et al TCT-254. Lipoprotein(a) Level and Two-Year Clinical Outcomes in Patients Undergoing Percutaneous Coronary Intervention with Drug-Eluting Stents Sang-Ho Park et al - N o v e m b e r 8 , 2 0 11 TCT-230. BIOSOLVE-I Optical Coherence Tomography (OCT) Results of Cohort 1 with the First Drug-Eluting Absorbable Metal Scaffold (DREAMS) Jacques Koolen et al TCT-241. NOYA I: A Prospective, Randomized Trial of NOYA Sirolimus-Eluting Stent with Biodegradable Coating Compared to FIREBIRD 2 Sirolimus-Eluting Stent with Durable Coating in Patients with Coronary Artery Disease Kefei Dou et al Tuesday TCT-229. First Report of a Novel Polymer-Free Dual-Drug-Eluting Stent in De Novo Coronary Artery Disease: Results of the First-in-Man BICARE Trial Mengyue Yu et al T r a n s c at h e t e r Cardiovascular Therapeutics TCT-255. Impact of ApoB/ApoA-I Ratio on Two-Year Clinical Outcomes in Patients Undergoing Percutaneous Coronary Intervention with Drug-Eluting Stents Sang-Ho Park et al TCT-256. Use of the HearTrial Catheter as a Distal Stent Delivery Device Darragh P. Moran et al TCT-257. Long-term Follow-up of the Platinum Chromium TAXUS Element (ION) Stent: PERSEUS Two-Year Results Louis A. Cannon et al TCT-258. Applying the National Institute for Clinical Excellence Criteria to Patients Treated with the Genous EPC-Capturing Stent: A Substudy of the e-HEALING Worldwide Registry Margo Klomp et al TCT-259. Response of Endothelial Progenitor Cells to Antiproliferative Drugs Currently Used in Drug-Eluting Stents Hao Xu et al TCT-260. Drug-Eluting Stent Failure: Report from the Swedish Angiography and Angioplasty Registry (SCAAR) Torsten Schwalm et al TCT-261. Long-term Clinical Outcomes from the Zotarolimus-Eluting Stent Program: Final Five-Year Pooled Results from the ENDEAVOR Program David E. Kandzari et al TCT-262. Serial Angiographic Follow-up After Successful Implantation of Sirolimus-, Paclitaxel-, Everolimus-, and ZotarolimusEluting Stents for Chronic Total Occlusions: Multicenter Registry in Asia Sunao Nakamura et al TCT-263. Elevated Preprocedural HighSensitive CRP Levels Are Associated with Uneven Vessel Healing After PaclitaxelEluting Stents Implantation in Patients with Stable Angina Hiromasa Otake et al www.tctconference.com 63 Tuesday, November 8 TCT-264. Twelve-Month Clinical Outcomes After Coronary Stenting with the Genous Bioengineered R Stent in Patients with a Bifurcation Lesion from the e-HEALING Registry Pier Woudstra et al TCT-275. Three-Year Outcomes of Chronic Total Occlusion Treatment with BiolimusEluting Biodegradable Polymer Stent vs. Sirolimus-Eluting Permanent Polymer Stent In the LEADERS All-Comers Trial Joanna J. Wykrzykowska et al TCT-287. Multicenter Clinical Trial with Everolimus-Eluting Stent for the Treatment of Bare Metal In-Stent Restenosis: Immediate and Long-term Clinical and Angiographic Outcomes Didier Carriè et al TCT-265. Impact of Stent Fracture on Stent Thrombosis After Drug-Eluting Stent and Bare Metal Stent Implantations Shunsuke Kubo et al TCT-276. New Generation Drug-Eluting Stent Nobori: Two-Year Clinical Outcome of Patients with Chronic Total Occlusion Bernard Chevalier et al TCT-288. Serial Morphological and Functional Assessment of In-Stent Restenosis Treated with Drug-Eluting Balloon Anouar Belkacemi et al TCT-266. Impact of Stent Length in Diffuse Coronary Disease on Clinical Outcome After Zotarolimus-Resolute-Eluting Stent Implantation: An Italian Multicenter Observational Evaluation Claudio Larosa et al TCT-277. Effect of Coronary Revascularization for Chronic Total Occlusions on Long-term Prognosis: Analysis of 585 Patients Mikhail A. Maslennikov et al TCT-289. The Pacifier Trial: A Randomized, Multicenter Trial Evaluating Prevention of Restenosis with Paclitaxel-Coated PTA Balloon Catheters in Stenosis or Occlusion of Femoropopliteal Arteries: First Report Michael Werk et al TCT-267. No Recovery of Drug-Eluting Stent Use in Clinical Practice in Europe After the Collapse Following Initial Reports of Impaired Outcomes in September 2006: Results of The Euro Heart Survey PCI-Registry Anselm K. Gitt et al TCT-268. Eight-Year Clinical Outcomes After Unrestricted Sirolimus-Eluting Stent Implantation for Severe Coronary Artery Disease Alfonso Ielasi et al Chronic Total Occlusions TCT-270. Multicenter Chronic Total Occlusion Intervention Experience in Korean Population: Korean Perspectives from Korean e-CTO Club Seung Woon Rha et al TCT-271. Impact of Multislice Computed Tomography in Evaluating Micro-Channels in Coronary Chronic Total Occlusion Lesions Prior to Percutaneous Coronary Intervention Masashi Kimura et al TCT-272. Impact of Stent Length on Long-term Clinical Outcomes of SirolimusEluting Stent Implantation for Chronic Total Occlusion Hiroyuki Tanaka et al TCT-273. Elective Stenting After Subintimal Tracking and Reentry (Star) Technique in Coronary Chronic Total Occlusions Gabriella Visconti et al TCT-274. Prognostic Impact of a Chronic Total Occlusion in a Non-Infarct-Related Artery in Patients with ST-Elevation Myocardial Infarction: Three-Year Results from the HORIZONS-AMI Trial Bimmer E. Claessen et al 64 program · TCT-278. Short- and Long-term Clinical Outcomes After Percutaneous Coronary Intervention in Patients with Chronic Total Occlusions: Results from a Multicenter, Prospective Study Shao-Liang Chen et al TCT-279. Impact of Lesion Length on Chronic Total Occlusion Intervention Outcomes Amro Elnagar et al In-Stent Restenosis and Drug-Eluting Balloons TCT-281. Three Different Strategies for Restenosis with Stent Fracture After Sirolimus-Eluting Stent Implantation: POBA vs. DES vs. DEB Suguru Otsuru et al TCT-282. Practice of Treatment of In-StentStenosis in PCI for ACS in Clinical Practice in Europe: Results of the EHS PCI Registry Anselm K. Gitt et al TCT-283. Impact of Initial Procedure and Revascularization Strategy on the Treatment of Drug-Eluting Stent Restenosis Following Unprotected Distal Left Main PCI: The Milan and New-Tokyo Registry Kensuke Takagi et al TCT-284. Paclitaxel-Eluting Balloon Catheter vs. Repeat Sirolimus-Eluting Stent for the Treatment of Sirolimus-Eluting Stent Restenosis Seiji Habara et al Left Main and Bifurcation Stenting TCT-290. Challenging Bifurcation Stenting: Clinical Outcomes at Two Years Bernard Chevalier et al TCT-291. Coronary Artery Bifurcation Stenting Using a Dedicated Sidebranch Stent Combined with DES (Facilitated Culottes): Two-Years Clinical Outcomes Solomon D. Asgedom et al TCT-292. Use of a Dedicated Sidebranch Device for Bifurcation Disease: A SingleCenter Experience of the TRYTON Stent Michael Norell et al TCT-293. Advanced Bifurcation Systems Mother-Daughter Platform in Complex Coronary Bifurcations: Prospective, Multicenter First-in-Man Experience Mehran J. Khorsandi et al TCT-294. Acute Procedural Outcome in Patients Treated with a Dedicated Bifurcation Stent for Left Main Stem Disease: The TRYTON LM Multicenter Registry Michael Magro et al TCT-295. Crush vs. Culotte for the Treatment of Coronary Bifurcations: Insights from a Long-term Follow-up Xavier Freixa et al TCT-285. Incidence of Acute Thrombosis After Percutaneous Coronary Intervention with Paclitaxel-Eluting Balloons in a Clinical Setting and in Clinical Trials Klaus Bonaventura et al TCT-296. Comparison of Ostial and Crossover Drug-Eluting Stent Implantation Technique for Medina (0,1,0) and (0,0,1) Bifurcated Lesion Yasunari Sakamoto et al TCT-286. Paclitaxel-Eluting Balloon for High Risk Coronary Lesions: One-Year Clinical Results with Angiographic Follow-up of a Multicenter Registry Beatriz Vaquerizo et al TCT-297. Periprocedural Myocardial Infarction Is Not Associated with Increased Risk of Long-term Cardiac Mortality After Coronary Bifurcation Stenting: Result from the COBIS Registry Pil Sang Song et al T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 TCT-300. Procedural Outcomes from the European Sideguard Registry Azeem Latib et al TCT-301. Sequential Sidebranch and Main Vessel Dilatation Instead of Kissing Balloon After Provisional Bifurcation Stenting: Lessons from Micro-CT and Computational Simulations Nicolas Foin et al TCT-302. Long-term Follow-up of SirolimusEluting Stent (SES) Implanted in Coronary Bifurcation Lesion: Insight from OCT Observations Hirotoshi Hariki et al TCT-303. Favorable Long-term Clinical Outcomes of Intravascular UltrasoundGuided Provisional Single-Stent Strategy for Feasible Unprotected Left Main Trunk Distal Bifurcation Lesions Takayoshi Toba et al TCT-304. True Bifurcation: A Special Subeset? Mario Bollati et al TCT-305. Left Main Percutaneous Coronary Intervention in Spain: The National Registry RENACIMIENTO Augustin Albarran G. Trevilla et al TCT-306. Use of the Novel Sideguard Dedicated Bifurcation Stent: A Real-World Experience Mamas Mamas et al TCT-307. Impact of Acute Coronary Syndrome on Clinical Outcomes in Patients with Coronary Bifurcation Lesions Treated with Drug-Eluting Stents. Pil Sang Song et al TCT-308. Left Main Bifurcation Stenting: Long-term Follow-up of Simultaneous Kissing Stents in 140 Consecutive, Unselected Patients Julian Gunn et al TCT-309. Outcomes Following Unprotected Left Main Stenting with Everolimus-Eluting Stents: The Milan Experience Gill L. Buchanan et al TCT-310. Treatment of Bifurcations with the Dedicated Sideguard Nitinol Stent Compared with Conventional Two-Stent Strategies Nicolas Foin et al TCT-312. Effect and Mechanisms of Coronary Bifurcation Angle from 3-D on Clinical Outcomes After Percutaneous Treatment with Stents: Results from DKCRUSH-II Trial Shao-Liang Chen et al TCT-313. Clinical Outcomes of Left Main Crossover Stenting Without Opening of Left Circumflex Coronary Artery Homyung Lee et al TCT-314. Predictive Factors of Long-term Outcomes After Crush Technique for Bifurcation Coronary Lesions Hae-Geun Song et al TCT-315. Acute Myocardial Infarction Due to Unprotected Left Main Coronary Artery Occlusion Treated with Primary Angioplasty Ivan Gomez et al TCT-316. First Generation vs. Newer Generation Drug-Eluting Stents in Unprotected Left Main Coronary Artery Intervention Amro Elnagar et al TCT-317. The SYNTAX Trial at Three Years: A Global Risk Approach to Identify Patients with Three-Vessel and/or Left Main Stem Disease Who Could Safely and Efficaciously Be Treated with Percutaneous Coronary Intervention (Part 1): The Randomized Population Patrick W. Serruys et al TCT-318. Bench Micro-CT Study and OCT Experience of a Final Proximal Postdilatation to Optimize Results in Bifurcation Stenting Nicolas Foin et al TCT-319. Left Main to Left Anterior Descending Artery or Left Main to Circumflex Stenting? This Is the Question Marco Di Cuia et al TCT-320. Natural History of Unprotected Sidebranch Jailed by Drug-Eluting Stent Masahiro Yamawaki et al TCT-321. Computational Analysis of Wall Shear Stress at the Distal Left Main Coronary Artery Bifurcation Wang Soo Lee et al TCT-322. Inmediate and Midterm Results of the E-Tryton Spanish Registry for the Treatment of Bifurcations Lesions Eulogio Garcia et al TCT-323. Five-Year Outcomes of SirolimusEluting Stent in Patients with Unprotected Left Main Coronary Arteries: The Milan and New-Tokyo Registry Kensuke Takagi et al TCT-324. Five-Year Results of Treatment of Unprotected Left Main Stenosis by CABG or PCI with Sirolimus-Eluting Stent: A Multicenter, Randomized Trial Enno Boudriot et al - N o v e m b e r 8 , 2 0 11 TCT-299. Clinical Outcomes of Periprocedural Myocardial Infarction After Intracoronary Stent Implantation for Bifurcation Lesion: Results from Coronary Bifurcation Stenting Registry (COBIS) Keun-Ho Park et al TCT-311. Healing Responses After Bifurcation Stenting with the Dedicated TRYTON Sidebranch Stent in Combination with XIENCE V Stents: An Angiography and Optical Coherence Tomography Study Christophe L. Dubois et al Tuesday TCT-298. Ischemia Detection by Intracoronary ECG After Stent Implantation in Coronary Bifurcation Lesions Dobrin Vassilev et al T r a n s c at h e t e r Cardiovascular Therapeutics STEMI Intervention TCT-328. Long-term Outcome After Percutaneous Coronary Intervention with Titanium-Nitride-Oxide-Coated Stents vs. Paclitaxel-Eluting Stents in Acute Myocardial infarction: A Five-Year Follow-up of the TITAX-AMI Trial Petri O. Tuomainen et al TCT-329. Prolonged Bivalirudin Infusion Is Associated with Enhanced ST-Segment Resolution Following Primary Percutaneous Coronary Intervention Bernardo Cortese et al TCT-330. DES vs. BMS in Large Coronary Arteries During Primary PCI Eva C. Sammut et al TCT-331. Predictors and Prognostic Consequence of Gastrointestinal Bleeding in Patients with ST-Elevation Myocardial Infarction Wouter J. Kikkert et al TCT-332. Four-Year Cardiovascular Event Rates Were Lower in Myocardial Infarction Patients with Early Increases in Mobilization of Oct-4-High Nanog-High Stem Cells Soon Jun Hong et al TCT-333. Impact of Positive Thrombus Retrieval During Primary Percutaneous Coronary Intervention with Thrombectomy on Infarct Size and Microvascular Obstruction Romain Chopard et al TCT-334. Equivalent Improvement of Cardiac Function After Delayed Reperfusion By Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Shinichiro Yamada et al TCT-335. Clinical Outcomes of Primary Percutaneous Coronary Intervention In Elderly vs. Younger Patients Presenting with Acute Myocardial Infarction (From the KAMIR) Jin Hee Choi et al TCT-336. Patient Differences by Mode of Hospital Arrival for ST-Elevation Myocardial Infarction Treated with Primary PCI Robert S. Lee et al www.tctconference.com 65 Tuesday, November 8 TCT-337. Does the Increase in Mortality in Patients with Acute Myocardial Infarction Admitted on Weekends Still Exist? Abhishek Deshmukh et al TCT-338. Associations Between Symptom-toDoor Time and Biomarkers on 12-Month Mortality in Patients with Acute Myocardial infarction Jang Hoon Lee et al TCT-339. Transradial Intervention Procedure for Unshock, ST-Segment Elevation Myocardial Infarction Patients with Palpable Radial Artery Hung M. Ngo et al TCT-340. Efficacy and Safety of The MGuard Stent in Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction Prodromos Anthopoulos et al TCT-341. Prognostic Consequence of Periprocedural Hemoglobin Decrease With and Without Observed Blood Loss in Patients with ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention Wouter J. Kikkert et al TCT-342. Accuracy of Acef, EuroScore and Syntax Score in Risk Stratification of Elderly (≥70 Years) Patients Undergoing Primary Angioplasty Flavia Ballocca et al TCT-343. In-Hospital Mortality of Patients Undergoing Primary Percutaneous Coronary Intervention: Validation of the EuroHeart STEMI PCI Score Ana Belen Cid Alvarez et al TCT-344. Postdischarge Bleeding and Thienopyridine Discontinuation Among AMI Patients Treated with PCI: Insights from the TRANSLATE-ACS Study Tracy Y. Wang et al TCT-345. Impact of the Novel Mobile Telemedicine System in Realtime Transmission of Prehospital 12-Lead ECG for ST-Segment Elevation Acute Myocardial Infarction Nobuhtio Yagi et al TCT-346. Routing Angioplasty After Fibrinolytic Therapy for ST-Segment Elevation Myocardial Infarction: An Updated Meta-analysis (RAFT-STEMI) Jose Donato A. Magno et al TCT-347. The Impact of Symptom-to-Door Time and Door-to-Balloon Time on 12-Month Mortality in Patients Undergoing Primary Percutaneous Coronary Interventions for ST-Segment Elevation Myocardial Infarction Jang Hoon Lee et al 66 program · TCT-348. Temporal Trends in Treatment and Outcomes of Patients with ST-Segment Elevation Myocardial Infarction in Clinical Practice: Analysis from the PL-ACS Registry Lech Polonski et al TCT-349. Monocyte Platelet Aggregate Act as Platelet Function Assay and Prognostic Marker for Acute Myocardial Infarction Ho Lam et al TCT-350. Very Late Hazard with Primary Stenting vs. Primary PTCA for STEMI: A 16-Year Single-Center Experience Bruce R. Brodie et al TCT-351. Impact of Bleeding on Mortality in Patients Referred for Primary PCI Michel Le May et al TCT-352. Prior Coronary Artery Bypass Graft (CABG) Patients Treated with Primary Percutaneous Coronary Intervention (PPCI) Have Higher Long-term Major Adverse Cardiovascular Event (MACE) Rates Mohammed M. Akhtar et al TCT-353. Time-to-Treatment and Infarct Size in STEMI Patients Undergoing Primary Angioplasty Guido Parodi et al TCT-354. Impact of Prehospital Activation Strategy on Revascularization Time, Left Ventricular Ejection Fraction, and Mortality in Patients with ST-Elevation Myocardial Infarction Sofia A. Horvath et al TCT-355. Does Thrombus Extraction from IRA During Rescue PCI After Prehospital Thrombolysis Improve Early and Midterm Follow-up in STEMI Patients? Anton Koledinsky et al TCT-356. Reperfusion Delay in Patients with ST-Elevation Myocardial Infarction Presenting to Hospitals Without Angioplasty Capability: Should “Door-to-Ambulance” Time Be The New Quality Parameter? Kishore Harjai et al TCT-357. Incidence and Predictors of Definite Stent Thrombosis After Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction in “Real-World” Patients Ivan Gomez et al TCT-358. Infarct Size Evaluation in Multidevice Thrombus Aspiration Study Elena Guerra et al TCT-359. Prognostic Value of the Syntax Score in Patients Undergoing Primary Percutaneous Coronary Intervention Ana Belen Cid Alvarez et al T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s TCT-360. Use of Thrombectomy Devices in Primary Percutaneous Coronary Intervention Neville Kukreja et al TCT-361. Safety and Efficacy of Biodegradable vs. Durable Polymer Drug-Eluting Stents: Evidence from a Meta-analysis of Randomized Trials Eliano P. Navarese et al TCT-362. The Impact of LV Function on the Mortality of Patients Undergoing Transcatheter Aortic Valve Implantation Yacine Elhmidi et al TCT-363. Cerebrovascular Events in Patients with ST-Segment Elevation Myocardial Infarction Undergoing a Primary PCI Management Strategy: Analysis from the HORIZONS-AMI Trial Eugenia Nikolsky et al TCT-364. The Association of Preinfarction Angina, Preprocedural Thrombolysis in Myocardial Infarction Flow, and Collateral Flow with Myocardial Salvage in Patients with ST-Segment Elevation Myocardial Infarction Jacob T. Lønborg et al TCT-365. Primary Percutaneous Coronary Intervention with Off-Site Cardiac Surgery Backup in Unselected Patients with ST-Segment-Elevation Myocardial Infarction: The RIvoli ST-Segment Elevation Myocardial Infarction (RISTEMI) Registry Francesco Tomassini et al TCT-366. Prognostic Role of Thrombus Aspiration and GP IIb/IIIa Inhibitors During Primary Percutaneous Coronary Intervention Stylianos A. Pyxaras et al TCT-367. Quantitative Proteomic Approach for Identification of Differentially Expressed Proteins After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction Sergio Alonso-Orgaz et al TCT-368. Copeptin: An Ultra Early Prognostic Marker for Acute Myocardial Infarction Ho Lam et al TCT-369. Prognosis After Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction Is Predicted by Extent and Complexity of Coronary Artery Disease as Assessed by the Syntax Score Adam J. Brown et al TCT-370. Door-to-Balloon Time and Long-term Clinical Outcome in Patients with STEMI Undergoing Primary PCI in Japan Hiroki Shiomi et al The World’s Premier Interventional Experience TCT2011 TCT-373. Influence of Acute Myocardial Infarction on the Incidence and Outcome of Early Surgical Procedure After Coronary Stent Implantation: A Report from the CREDO-Kyoto Registry Cohort 2 Akihiro Tokushige et al TCT-374. Twelve-Month Mortality of NSTEMI Patients Treated by PCI with Multivessel Disease and Chronic Total Occlusions: Analysis from the PL-ACS Registry Mateusz Tajstra et al TCT-375. Select EKG Characteristics Predict Door to Balloon Time In Primary PCI for STEMI Rajinder S. Marok et al TCT-376. Relationship Between Elevated BNP Levels in STEMI and Clinical Outcomes: The HORIZONS-AMI Trial Rudolf Jarai et al TCT-377. The Impact of the Location of a Chronic Total Occlusion in Conjunction with the Location of the Infarct Related Artery on Long-term Mortality in ST-Elevation Myocardial Infarction Patients Loes P. Hoebers et al TCT-379. Routine Thrombus Aspiration and Glycoprotein Inhibitor Use During Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction: Do All Patients Benefit? Liam M. McCormick et al TCT-380. No Difference in Periprocedural Myocardial Infarction Between Direct Stenting and Balloon Predilatation During Elective Percutaneous Coronary Intervention Gabriel L. Sardi et al TCT-381. Improvement of Early Invasive Treatment for NSTE-ACS Over Time in Clinical Practice in Europe: Results of the EHS ACS Registry Anselm K. Gitt et al Unstable Angina and NSTEMI Intervention TCT-382. Influence of Chronic Pulmonary Disease on In-Hospital Outcome in 21,576 Patients with Acute Coronary Syndromes: Data from Euro Heart Survey ACS III Registry (2006-2008) Wojciech Wojakowski et al TCT-384. Incidents and Types of Ischemic Events Detected Using Permanent Intracardiac ST-Segment Monitoring: First-in-Human Experience Mitchell W. Krucoff et al TCT-385. Thrombus Aspiration vs. Local Intracoronary Delivery of Abciximab In Acute Coronary Syndromes: An OCT Study Fabrizio Imola et al TCT-386. Admission Electrocardiogram Analysis for the Prediction of Long-term Outcomes After Non-ST-Elevation Acute Coronary Syndrome Peter Damman et al TCT-387. Prognosis of Patients Presenting with Acute Coronary Syndromes with Elevated Serum Troponins and Nonobstructive Coronary Artery Disease: The ACUITY Trial David Planer et al TCT-388. A “Direct” Transfer Protocol for Patients with Non-ST-Elevation Myocardial Infarction Reduces Time to Coronary Angiography Sean Gallagher et al TCT-389. Are Adverse Events Following an Invasive Strategy in Patients with Non-STSegment Elevation Acute Coronary Syndromes (NSTEACS) More Frequent at US Sites vs. Non-US Sites (OUS)? Analysis from the ACUITY Trial Patrick Tobbia et al PCI Outcomes TCT-390. A Prospective Appropriate Use Criteria Tool Aids Revascularization Decision-Making in the Catheterization Laboratory Michael A. Wilson et al TCT-391. Red Blood Cell Transfusion and Long-term Major Adverse Events in Patients Undergoing Percutaneous Coronary Interventions: Results from a Large Prospective Multicenter Registry—the STENT Group Hiroki Ito et al TCT-392. The Frequency and Etiology of Readmission in the 30 Days After Percutaneous Coronary Intervention Gregory W. Yost et al TCT-393. Incidence, Predictors, and Long-term Clinical Outcomes of Coronary Perforation in the Modern Era Samer Mansour et al TCT-394. Early and Long-term Results After Five-Hour Discharge Percutaneous Coronary Interventions R. Stefan Kiesz et al TCT-395. Study Modifications and Primary Endpoint Reinterpretations Prior to FDA Approval of High-Risk Cardiovascular Devices Sanket S. Dhruva et al TCT-396. Percutaneous Coronary Intervention in Patients with Severe Left Ventricular Dysfunction: A Meta-analysis of 19 Studies Vijay Kunadian et al - N o v e m b e r 8 , 2 0 11 TCT-372. Prehospital ECG Triage Strategy vs. Interhospital Transfer for STEMI Albert Chan et al TCT-383. Effect of Chronic Use of Vitamin K Antagonists on In-Hospital Outcomes of Patients Presenting with Acute Coronary Syndromes: Data from 19,000 Patients from EuroHeart Survey ACS III Registry (2006-2008) Wojciech Wojakowski et al Tuesday TCT-371. Frequency and Predictors of Drug-Eluting Stents Implantation in Patients with Acute Myocardial Infarction: Analysis from the PL-ACS Registry Marek Gierlotka et al T r a n s c at h e t e r Cardiovascular Therapeutics TCT-397. Statin Therapy Reduces Late Target Lesion Revascularization After SirolimusEluting Stent Implantation Masahiro Natsuaki et al TCT-398. Married Patients Suffer Less Death and Myocardial Infarction After Percutaneous Coronary Intervention Michael A. Gaglia et al TCT-399. Pressure-Controlled Intermittent Coronary Sinus Occlusion (PICSO): Results From the First-in-Man Prepare PICSO Pilot Study Tim P. van de Hoef et al TCT-400. Correction of Anemia During Follow-up Periods Improves Clinical Outcomes in Patients Who Underwent Drug-Eluting Stents Pum-Joon Kim et al TCT-401. Determining a Troponin I Threshold for Predicting 30-Day Mortality: Results from the Troponin I In the Emergency Room (TiER) Study Saman Fakheri et al TCT-402. Regular Exercise Improve FMD, Carotid IMT, and EPC in PCI Patients Je Sang Kim et al TCT-403. Could Mean Platelet Volume Be a Predictive Marker for One-Year Clinical Outcomes in Patients Who Underwent Percutaneous Coronary Intervention? Cheol Ung Choi et al TCT-404. Age and Five-Year Outcomes After a Routine or Selective Invasive Strategy for Non-ST-Segment Elevation Acute Coronary Syndromes Peter Damman et al TCT-405. Rotational Atherectomy Following by Second Generation Drug-Eluting Stents Implantation Against Heavily Calcified Coronary Lesions Munetaka Yamaguchi et al www.tctconference.com 67 Tuesday, November 8 TCT-406. Syntax Score Does Not Add to Clinical Risk Score in a Typical PCI Population Julian Gunn et al Heart Disease in Women TCT-416. Female Patients with Acute Coronary Syndrome: Two-Year Clinical Outcomes Philip Urban et al TCT-417. Gender-Specific Outcomes After Paclitaxel-Eluting Stent Implantation in Japanese Patients with Coronary Artery Disease: A Subanalysis of Japan TAXUS Express2 Postmarketing Survey Hiroyuki Okura et al TCT-418. Bivalirudin Use During Percutaneous Coronary Intervention Improves Clinical and Economic Outcomes in Diabetic Women Erin M. Galbraith et al TCT-419. Outcomes of Women After Acute Myocardial Infarction: Results from the HORIZONS-AMI Study Jennifer Yu et al TCT-420. Predictors of Major Adverse Events in Female Patients with Acute Myocardial Infarction Undergoing Primary PCI: Three-Year Results from the HORIZONS-AMI Study Jennifer Yu et al TCT-421. The SPIRIT WOMEN Single Arm Study: Two-Year Follow-up Results Marie-Claude Morice et al TCT-422. Nonatherosclerotic Coronary Artery Disease in Young Women Jacqueline Saw et al TCT-423. Higher Rates of Repeat Revascularization in Young Women Undergoing Percutaneous Coronary Intervention: Results from the NHLBI Dynamic Registry Kelly C. Epps et al TCT-424. Do Women Continue to Have Longer Door-to-Balloon Times in the Era of STEMI Systems? Melissa Blondeau et al Heart Disease in Diabetics TCT-426. Diabetes Mellitus Requiring Insulin and High Residual Platelet Reactivity After Clopidogrel Loading Dose Are Predictors of Long-term Clinical Outcome in Patients with Acute Coronary Syndrome: The RECLOSE2ACS Diabetes Mellitus Substudy Renato Valenti et al 68 program · TCT-427. Clopidogrel Hyporesponsiveness, Interacting with Diabetes Mellitus, Predicts Two-Year Cardiovascular Outcome Among Taiwanese Population Underging Percutaneous Coronary Intervention Ping-Yen Liu et al TCT-428. Effects of Low Dose Pioglitazone on Restenosis and Atheroma Plaques in Patients with Diabetes Mellitus Undergoing Percutaneous Coronary Intervention Sung Gyu An et al TCT-429. Clinical and Angiographic Results of the Titanium vs. Everolimus Stent in Diabetic Patients Randomized Trial (TITANIC-XV) Jose Ramon Lopez-Minguez et al TCT-430. Two-Year Clinical Outcomes of Diabetic Patients Treated with a New Generation Drug-Eluting Stent Francesco Saia et al TCT-431. Coronary Plaque Characteristics in Diabetic and Nondiabetic Patients Evaluated by Integrated Backscatter Intravascular Ultrasound Yoshinori Miyamoto et al TCT-432. Impaired Lung Function is an Independent Predictor of Type 2 Diabetes in Korean Men: Five-Year Follow-up Study Ki-Chul Sung et al TCT-433. Does Diabetes Mellitus Impact Clinical Outcomes Following Chronic Total Occlusion Intervention with DrugEluting Stents? Amro Elnagar et al TCT-434. Impact of Chronic Dialysis on Below-the-Knee Intervention Outcomes in Patients with Critical Limb Ischemia Amro Elnagar et al TCT-435. Long-term (Five-Year) Outcomes of Drug-Eluting Stents and Coronary Artery Bypass Grafting for Multivessel Coronary Revascularization in Diabetic and Nondiabetic Patients Yong-Giun Kim et al TCT-436. Clinical Outcome in Diabetic Patients Treated for Coronary Bifurcation Lesions by Drug-Eluting Stents: Pooled Analysis of the BBC ONE Study and the Nordic Bifurcation Studies Michael Maeng et al Heart Disease in the Elderly TCT-407. Population-Based Analysis of the Epidemiology and Reintervention Rates of Cardiovascular Stenting Procedures: A Medicare Study Jasmine D. Patel et al T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s TCT-408. Effect of Invasive Strategy on Long-term Outcome in Elderly Chinese Patients with Non-ST-Elevation Myocardial Infarction Shao-Sung Huang et al TCT-409. Long-term Clinical Follow-up of Percutaneous Coronary Intervention in Nonagenarians Paolo Angioli et al TCT-410. Impact of Age for Treatment of Acute Coronary Syndromes in Elderly Patients Harald Rittger et al TCT-411. Survival and Discharge Rates for Octogenarians Undergoing Coronary Revascularization Procedures After Acute Myocardial Infarction Abhishek Deshmukh et al TCT-412. Impact of Age on Coronary Endothelial Dysfunction in Patients with Myocardial Bridge Amro Elnagar et al TCT-413. Safety and Efficacy of the Resolute Zotarolimus-Eluting Stent in Patients ≥70 Years of Age Ganesh Manoharan et al TCT-414. Predictors of In-Hospital Mortality in Acute Myocardial Infarction in Elderly Patients Harald Rittger et al TCT-415. Impact of Old Age on Clinical and Angiographic Characteristics of Coronary Artery Spasm as Assessed by Acetylcholine Provocation Test Woong Gil Choi et al Basic Science, Animal Models, and Preclinical Studies TCT-437. The Mitochondrial Permeability Transition Pore is a Target for Pharmacological Cardioprotection in Human Hypertrophic Cardiomyopathy Paul S. Rees et al TCT-438. Atorvastatin, Administered at the Onset of Reperfusion, Protects Human Myocardium Against Lethal Reperfusion Injury by Activation of the RISK Pathway Paul S. Rees et al TCT-439. Periadventitial Delivery of a Nanoparticle Albumin-Bound (Nab) Rapamycin Solution Reduces Luminal Stenosis in a Porcine Femoral Artery Balloon Injury Model Warren J. Gasper et al The World’s Premier Interventional Experience TCT2011 TCT-442. The Controlled Reperfusion with Bivalirudin and Intracoronary Abciximab in the Porcine Mycoardial Infarction/ Reperfusion Model Piotr P. Buszman et al TCT-443. Systemic and Local Tissue Pharmacokinetics of Single and Overlapping NEVO Sirolimus-Eluting Stents in the Porcine Coronary Artery Model Rami Tzafriri et al TCT-444. Antiinflammatory Effect of Arsenic Trioxide-Eluting Stents in a Porcine Coronary Model Li Shen et al TCT-445. Optical Characteristics of Neointimal Formation Correlate with Histological Markers of Stent Healing in a Porcine Model of Restenosis Jung-Sun Kim et al TCT-446. Short-term Effects of SirolimusEluting Fully Bioabsorbable Polymeric Coronary Stents in a Porcine Model Li Shen et al TCT-447. Angiographic and Histological Response Following Implantation of a Novel Stent-on-a-Wire in the Animal Model Roberto Diletti et al TCT-448. Scanning Electron Microscopic Observation of Coating Irregularities and Their Precursors in Unexpanded Durable Polymer-Based Drug-Eluting Stents Mounir W. Basalus et al TCT-449. Preclinical Evaluation of a Myolimus-Eluting Bioresorbable Polymeric Scaffold in the Porcine Coronary Artery Model Guy Leclerc, MD et al TCT-450. Insights from Network Analysis: Deficiency of Glutathione Peroxidase-1 Increases In-Stent Stenosis Ziad A. Ali et al TCT-451. Right Through the Heart: Transseptal Access for Stent-Graft placement in the Ascending Aorta Sabine H. Wipper et al TCT-453. Early Enzymatic Infarct Size Assessment Using Heart Specific Fatty Acid Binding Protein Andre Uitterdijk et al TCT-454. A Highly Reproducible and Clinically Relevant Large Animal Model of Myocardial Ischemia and Heart Failure as Determined by MRI Imaging Michael B. Sweet et al TCT-455. Evaluation of Second Generation DES in an Ex Vivo Model of Stent Thrombosis Alexander Sheehy et al TCT-456. Microarray Analysis for Nobori Biolimus A9-Eluting Stent and Xience V Everolimus-Eluting Stent in Porcine Coronary Artery Arihiro Sumida et al TCT-457. Evaluation of Drug Tissue Concentration Following Stenting in a Healthy Rabbit Iliac Model Alexander Sheehy et al TCT-458. Which Genes of the Nitric Oxide Pathway Contribute to Vascular Dysfunction Following DES Implantation in Swine Coronary Arteries? Selvamuthu K. Natarajan et al TCT-459. Pharmacokinetic Evaluation of Drug-Eluting Stents in a Healthy and Atherosclerotic Rabbit Iliac Model Alexander Sheehy et al TCT-460. Anatomic Substrate for Renal Sympathetic Denervation: A Human Post-Mortem Histological Study Farrell O. Mendelsohn et al TCT-461. Animal Studies on the Mechanisms and Radiofrequency Catheter Ablation of the Syncope with Vasovaga1 Syncope: Radiofrequency Ablation of Cardiac Nerve Attenuates Bezold-Jarisch Reflex in Canine Chunshan Lu et al TCT-462. Percutaneous Renal Sympathetic Denervation Exerts a Chronic Effect on Renal Hemodynamics and Plasma Norepinephrine Levels Using a Novel Catheter for Radiofrequency Ablation: Data from an Animal Study Konstantinos Tsioufis et al TCT-463. Characterization of Cellular Responses to Stent Materials Jeffrey S. Garanich et al TCT-464. Acute Effect of Percutaneous Renal Sympathetic Denervation on Renal Hemodynamics Using a Novel Radiofrequency Ablation Catheter in a Swine Model Vasilios Papademetriou et al TCT-465. Impact of the Different Route of Cell Delivery in Chronic Ischemic Cardiomyopathy Ovine Model Yanping Cheng et al TCT-466. Circadian Body Temperature Variability Corresponds to Significant Decline in Left Ventricular Function in Cardiomyopathic Hamsters Amany Ahmed et al - N o v e m b e r 8 , 2 0 11 TCT-441. Periadventitial Renal Artery Delivery of Guanethidine Monosulfate Attenuates Renal Nerve Function: Preclinical Experience and Implication for Resistant Hypertension Christopher D. Owens et al TCT-452. Increased Endothelial Tetrahydrobiopterin Reduces In Stent Stenosis in Apolipoprotein E-Knockout Mice Ziad A. Ali et al Tuesday TCT-440. Allogeneic Mesenchymal Precursor Cells Reduce Infarct Size and Preserve Cardiac Function Following Intracoronary Infusion in a Sheep Model of Acute Myocardial Infarction Jaco Houtgraaf et al T r a n s c at h e t e r Cardiovascular Therapeutics TCT-467. Quantitative OCT Analysis of In-Stent Neointimal Growth After Implantation of ABSORB BVS in a Diabetic Animal Model Nienke van Ditzhuijzen et al Cardiogenic Shock, Heart Failure, and Hemodynamic Support TCT-468. The Impact of Revascularization and Optimal Medical Therapy on Six-Month Clinical Outcome in Patients With and Without Congestive Heart Failure After Acute Myocardial Infarction Jang Hoon Lee et al TCT-469. Comparison of Clinical Outcomes Between Infarct-Related Artery Revascularization Only and Multivessel Revascularization in Patients with Acute Myocardial Infarction and Cardiogenic Shock Ju Yeol Baek et al TCT-470. Early Hemodynamic Support with Impella 2.5 Improves Survival in Refractory Cardiogenic Shock After Acute Myocardial Infarction Brijeshwar Maini et al TCT-471. Radial vs. Femoral Approach in Primary PCI for STEMI with Cardiogenic Shock: Prospective Comparison Ivo Bernat et al TCT-472. Gradual Decline in the Age-Adjusted Mortality Rate from Cardiogenic Shock of Any Cause or in the Setting of ST-Elevation Myocardial Infarction in the United States Mohammad Reza Movahed et al TCT-473. Suppression of Oxidative Stress in Endovascular Hypothermia-Treated Patients with Acute Myocardial Infarction and Cardiac Arrest Petr Ostadal et al TCT-474. Improvements in LV Function and Afterload with TandemHeart for the Treatment of Refractory Cardiogenic Shock Michael Tempelhof et al www.tctconference.com 69 Tuesday, November 8 TCT-475. Gradual Reduction in the AgeAdjusted Nationwide Trends in the Incidence of Cardiogenic Shock Occurring in the Setting of ST-Elevation Myocardial Infarction Across Different Ethnicities and Gender in the United States Mohammad Reza Movahed et al TCT-476. New Definition for Stress-Induced Cardiomyopathy: The Gothenburg Criteria Elmir Omerovic TCT-477. No Reduction in the Age-Adjusted Nationwide Trends in the Incidence of Cardiogenic Shock in the United States Irrespective of Gender or Ethnicities Mohammad Reza Movahed et al TCT-478. Epicardial Catheter-Based Ventricular Reconstruction Restores Left Ventricular Rotation and Reverses Myocardial Remodeling in an Ovine Model of Left Ventricular Aneurysm Yanping Cheng et al TCT-479. The Utility of Remote Wireless Pulmonary Artery Pressure Monitoring in Patients With or Without a History of Myocardial Infarction: Experience from the CHAMPION Trial Warren L. Strickland et al TCT-480. Safety and Feasibility of Percutaneous Delivery of a Partial Left Ventricular Support Device (CircuLite Synergy Micro-Pump) in a Porcine Model Geng-Hua Yi et al TCT-481. Diastolic Heart Failure: Innovative Extra- and Intraventricular Solutions Mitchell W. Krucoff et al TCT-482. A Prospective Multicenter Randomized Clinical Trial of Intraaortic Balloon Pump vs. Impella for Hemodynamic Support During High-Risk PCI: Final Clinical and Angiographic Results of PROTECT II William O’Neill et al TCT-483. Is It Appropriate to Take All Postresuscitation Patients Suspected of Having an Acute MI for Urgent Angiography? Vivek K. Reddy et al TCT-484. Cost-Effectiveness and Clinical Outcomes of Impella Hemodynamic Support Compared with Intraaortic Balloon Pump in High-Risk Patients Receiving PCI: Results from the PROTECT II Trial Brijeshwar Maini et al TCT-485. Aspiration of the Blood from the Left Ventricular Cavity to Treat Refractory Ventricular Arrhythmias During Complex Coronary Interventions Waleed Y. Kadro et al 70 program · TCT-486. Medical Treatment and Coronary Angioplasty in Patients with Severe Left Ventricular Dysfunction and Coronary Artery Disease Diego D. Grinfeld et al TCT-487. Coronary Sinus Technique in End Stage Heart Failure Jorge Tuma et al TCT-488. Percutaneous Retrograde Left Ventricular Assist Support for Patients with Aortic Stenosis and Left Ventricular Dysfunction Claudia A. Martinez et al TCT-489. Predictive Value of EuroScoreDerived Parameters for the Development of Right Ventricular Failure After Cardiac Surgery Annemarie Engstrom et al TCT-490. Complete Revascularization Improves Survival in Patients with STEMI Complicated by Cardiac Arrest and Cardiogenic Shock Darren Mylotte et al TCT-491. Percutaneous Left Ventricular Support with the Impella 2.5 Assist Device in Severe Cardiogenic Shock Markus Ferrari et al TCT-492. Interim Analysis of the Reitan Catheter Pump (RCP) Heart Failure Efficacy Study: RCP Improves Cardiovascular and Renal Function in Acute Decompensated Heart Failure (ADHF) Thomas R. Keeble et al Contrast-Induced Nephropathy and Chronic Kidney Disease TCT-493. Biomarkers to Predict ContrastInduced Nephropathy After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction: A HORIZONS-AMI Substudy Bimmer E. Claessen et al TCT-494. Impact of Renal Impairment on Clinical and Angiographic Outcomes After Percutaneous Coronary Intervention with Drug-Eluting Stents: A Pooled Analysis of SIRTAX, LEADERS, and RESOLUTE All-Comers Trials Giulio G. Stefanini et al TCT-495. The Effect Of Cilostazol on the Antiplatelet Efficacy of Patients with Moderate Renal Dysfunction: Post-hoc Analysis of CILON-T (Influence of CILostazol based triple antiplatelet therapy ON ischemic complication after drug-Eluting Stent implantation) Trial Min-Ho Lee et al T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s TCT-496. Objectives: The Purpose of This Study Was to Determine the Functional Impact of Cilostazol in Patients with Chronic Kidney Disease (CKD) Undergoing Hemodialysis Weon Kim et al TCT-497. Duration of Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation in Patients with Chronic Kidney Disease: A Report from the National Heart, Lung, and Blood Institute Dynamic Registry Joseph Kim et al TCT-498. The Prognostic Value of Admission Serum Creatinine for Contrast-Induced Nephropathy and 12-Month Mortality In Patients with Acute ST-Elevation Myocardial Infarction Underwent Primary Percutaneous Coronary Intervention Han-Young Jin et al TCT-499. Comparison of Four-Year Clinical Outcomes of Stent Implantation in Renal Failure Patients with Dialysis: Comparison with Bare Metal Stents and First and Second Generation Drug-Eluting Stents Sunao Nakamura et al TCT-500. Effectiveness of Theophylline in Prevention of Contrast-Induced Nephropathy in Risky Egyptian Patients Undergoing Elective Coronary Angiography or Percutaneous Intervention: A Randomized, Controlled Trial Mohammed Elshawadfy et al TCT-501. Baseline Renal Dysfunction is Associated with Worse Outcomes in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction Sean Gallagher et al TCT-502. Cystatin C Is Superior Diagnostic Tool Compared with Conventional Serum Creatinine or Estimated Glomerular Filtration Rate in Prediction of ContrastInduced Nephropathy Hyuck Jun Yoon et al TCT-503. Relationship Between Syntax Score and Contrast-Induced Acute Kidney Injury in Patients with CKD Undergoing Coronary Angiography or PCI Ayesha C. Qureshi et al TCT-504. Clinical Impact of Renal Function Recovery After Contrast-Induced Nephropathy on Long-term Adverse Events Hyuck Jun Yoon et al TCT-505. Contrast-Induced Acute Kidney Injury In Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction: A Randomized Trial on Hydration with Saline or Bicarbonate Mila Menozzi et al The World’s Premier Interventional Experience TCT2011 TCT-508. The Dynamic Hemodialysis to Prevent Contrast-Induced Nephropathy in Catheterization Laboratory Osamu Matsuda et al TCT-509. High Concentration Sodium Bicarbonate for the Prevention of ContrastInduced Nephropathy Nozomu Tamai et al TCT-510. Use of Paclitaxel-Eluting Stents Reduces Target Lesion Revascularization for Dialysis Patients Hirotoshi Watanabe et al TCT-511. Tridimensional Rotational Angiography and Transplant Renal Artery Stenosis: 40-Case Analysis Erlon O. Silva et al Vascular Access and Closure TCT-513. Transradial Approach for Coronary Procedures: Confronting the Myth of Prolonged Preparation Time Sara V. Sloan et al TCT-514. Radiation Exposure During Percutaneous Coronary Interventions and Coronary Angiograms Performed by the Femoral Route as Compared to the Radial Route Ronak Delewi et al TCT-515. Outcome and Safety of Same-Day Discharge Percutaneous Coronary Interventions with Femoral Access: A Single-Center Experience Lisbeth Antonsen et al TCT-516. Impact of Increased Distance on Operator Radiation Exposure During Transradial Catheterization Ranya N. Sweis et al TCT-517. Safety and Efficacy of Ulnar Approach: A New Route for Cardiac Catheterization and Intervention Luis Jhonathan Uribe Gonz·lez et al TCT-518. Radial vs. Femoral Access Approaches in Percutaneous Coronary Intervention of Patients Receiving Bivalirudin Martial Hamon TCT-520. Transradial Approach to Coronary Interventions: How Steep Is the Learning Curve for Trained Interventional Cardiologists? Bharat Gummadi et al TCT-521. Safety and Efficacy of Radial Arterial Injection of Nicorandil Compared to the Usual Cocktail of Nitroglycerine (NTG) and Diltiazem Given During Radial Angiography Jamshed J. Dalal et al TCT-522. Comparison of Clinical Outcomes Between Transradial and Transfemoral Access in Patients with Acute Myocardial Infarction: Results from the Korea Acute Myocardial Infarction Registry Kwang S. Cha et al TCT-523. Influence of Access Site Selection on PCI-Related Adverse Events in STEMI Patients; Meta-analysis of Randomized Controlled Trials Karim Ratib et al TCT-524. Transradial vs. Transfemoral Approach in Elderly Patients with ST-Segment Elevation Acute Myocardial Infarction Treated with Primary Angioplasty: Feasibility, Predictors of Success, and Outcome Victor A. Jimenez Diaz et al TCT-525. Impact of Low-Molecular-Weight Heparin on Reperfusion Rates in Patients with Radial Artery Occlusion after Cardiac Catheterization. Results and Follow-up in 113 Patients Madlen Uhlemann et al TCT-526. Radial vs. Femoral Approach for Primary Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction: An Update Meta-analysis Jae-Sik Jang et al TCT-527. Transulnar and Transradial Approach for Coronary Intervention: A Comparative Study Adolfo G. Lopez Campanher et al TCT-528. Feasibility of Transradial Coronary Intervention for Chronic Total Occlusions Yutaka Tanaka et al TCT-529. Single-Center Registry of Percutaneous Ulnar Artery Approach for Coronary Intervention as an Alternative to Transradial Access Sashko Kedev et al TCT-530. Transradial and Transulnar Coronary Diagnostic and Interventional Procedures Performed Using Color: Doppler Guidance Sanjay K. Chugh et al TCT-531. Transradial vs. Transfemoral Approach for Chronic Total Occlusion of Coronary Arteries: Feasibility and Predictors of Success Victor A. Jimenez Diaz et al TCT-532. Is Verapamil in Transradial Interventions Omittable? The VITRIOL Trial Istvan Hizoh et al TCT-533. Effect of Adopting a Transradial Access Program on Resource Utilization and Efficiency of an Academic Cardiac Catheterization Laboratory Joshua Stolker et al - N o v e m b e r 8 , 2 0 11 TCT-507. Contrast-Induced Nephropathy in Patients with Normal Renal Function Undergoing Complex PCI with High Dose of Contrast Media: Predictive Value of Cystatin C Norbert Mayaud et al TCT-519. Radial vs. Femoral Access in Patients Referred for Primary Percutaneous Coronary Intervention: Characteristics and Clinical Outcomes Samer Mansour et al Tuesday TCT-506. Invasive Treatment of Patients with Non-ST-Segment Elevation Myocardial Infarction and Severe Renal Dysfunction: Early and 12-Month Outcomes from the PL-ACS Registry Marek Gierlotka et al T r a n s c at h e t e r Cardiovascular Therapeutics TCT-534. Transradial Coronary Angiography via Right or Left Radial Artery Approaches in Real-World Practice: A PREVAIL Study Data Subanalysis Francesco Pelliccia et al TCT-535. Shortened Time to Hemostasis, Sitting up, and Ambulation with a Novel Access Technology for Femoral Artery Catheterization: Results of the RECITAL Trial Dale C. Wortham et al TCT-536. Femoral Artery Complications Associated with Mynx vs. Suture-Mediated Closure Device vs. Collagen-Based Closure Device Itsik Ben-Dor et al TCT-537. Influence of Vascular Closure Devices on Femoral Access Site Related Bleeding in ST-Elevation Myocardial Infarction Sophie H. van Nes et al TCT-538. Routine Use of the Transradial Approach in Primary Percutaneous Coronary Intervention: Procedural Aspects and Outcomes in 2,209 Patients Treated in a Single, High-Volume Center Maarten Vink et al TCT-539. Same Wrist Intervention via the Cubital (Ulnar) Artery in Case of Radial Puncture Failure for Percutaneous Cardiac Catheterization or Intervention: The Multicenter Prospective SWITCH Registry Pierfrancesco Agostoni et al TCT-540. Resource Utilization for Propensity Matched Radial and Femoral Catheterization and Intervention Pascha E. Schafer et al TCT-541. Comparison of Transradial and Transfemoral Approach for Carotid Artery Stenting: Radcar Study Zoltan Ruzsa et al www.tctconference.com 71 Tuesday, November 8 TCT-542. Procedural Trends Associated with Successful Initiation of a Transradial Program at an Academic Training Institution Usman Javed et al Peripheral Vascular Intervention (Noncarotid and Nonneurovascular) Carotid and Neurovascular Intervention TCT-554. The Iliac Sidebranch: For All or Only the Few? A Morphological Suitability Study Daphne Pavlidis et al TCT-543. Safety of Carotid Stenting (CAS) Is Based on the Center Experience More Than on the Individual Performance Paola De Rango et al TCT-544. The Safety and Feasibility of Sheathless Transradial Carotid Artery Stenting (Comparing with Transbrachial Carotid Artery Stenting) Hsiu-Yu Fang et al TCT-545. Carotid Artery Stenting in Patients With and Without Contralateral Stenosis (≥50%) Alexander Kypta et al TCT-546. Novel Predictors for In-Stent Restenosis (ISR) After Carotid Artery Stenting (CAS) Roland R. Macharzina et al TCT-547. Transcatheter Laser Revascularization of Brain Vessels in the Treatment of Vascular Dementia Ivan V. Maksimovich TCT-548. Outcomes of Modern Endovascular Treatment of Vein of Galen Malformations in the Neonatal Period Alejandro Berenstein TCT-549. Selective Basilar Artery Thrombolysis for Posterior Territory Stroke: Acute Stroke Registry from Western India Kamaldeep Chawla et al TCT-550. Carotid Stent Placement (CAS) With or Without Debris Aspiration Prior to Embolic Protection (EDP) Retrieval: A CHOICE Registry Subset Study Thomas K. Pow et al TCT-551. Inflammatory Markers Predict Future Cardiovascular Events in Patients Undergoing Carotid Stenting Francesco Versaci et al TCT-552. Fasttrack Carotid Surgery Is the Gold Standard for High-Risk (HRP) Carotid Artery Intervention: Five-Year CostEffectiveness and Quality Stroke-Free Survival Comparison Sherif Sultan et al TCT-553. The Impact of Periprocedural Myocardial Infarction on Long-term Outcomes After Carotid Artery Stenting Christopher Metzger et al 72 program · TCT-555. Higher CD34+ Cells Concentration and Lower Degree of Inflammation Are Associated with Better Therapeutic Response to Autologous Bone Marrow Cells Application in Patients with Critical Limb Ischemia Juraj Madaric et al TCT-556. Percutaneous Transluminal Angioplasty of the Subclavian Arteries: Long-term Follow-up Michel Henry et al TCT-557. Thoracic Abdominal Endovascular Aneurysm Repair (TEVAR) in the Management of Acute Aortic Syndrome (AAS). An Early Experience with Debranching, Chimney Techniques, and Multilayer Stenting Sherif Sultan et al TCT-558. Five-Year THUNDER Follow-up: Patients with PAD Treated with Uncoated vs. Paccocath PaclitaxelCoated Balloons Gunnar Tepe TCT-559. Impact of Angiosome Approach on Clinical Outcomes of Endovascular Therapy in Patients with Critical Limb Ischemia Presenting with Isolated Below-the-Knee Lesions Kiyonori Nanto et al TCT-560. Results of the CONFIRM II Study Demonstrate the Value of Orbital Technology in Effectively Restoring Flow in Patients with Calcified Infrainguinal Disease Gaurav Aggarwala et al TCT-561. New Conformable Thoracic Stentgraft (SG): Apposition Scoring in the Thoracic Aorta Near the Arch Michael Gawenda et al TCT-562. Retrograde Transpedal Access for Below-the-Knee Chronic Total Occlusions After Failed Anterograde Recanalisation Zolt·n Ruzsa et al TCT-563. Five-Year Trial of TASC II Type C/D Lesions Undergoing Subintimal Angioplasty or Bypass Surgery Based on Plaque Echolucency Niamh Hynes et al TCT-564. Vertebral Angioplasty Stenting. Are Protection Devices Useful? Michel Henry et al T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s TCT-565. The Role of Pull-Back Pressure Gradient in Percutaneous Transluminal Angioplasty for Central Vein Stenosis in Dialysis Patients Yu Sheng Lin et al TCT-566. Nitinol Stent Implantation for TASC C and D Lesions in the Superficial Femoral Artery (STELLA Trial) Yann GouÎffic et al TCT-567. The Multilayer Stent for the Treatment of Popliteal Aneurysm Michel Henry et al TCT-568. Ten-Year Outcomes After Revascularization of Peripheral Arterial Disease with Adjunctive Atherectomy Alix J. Tercius et al TCT-569. Prognosis of Chronic Hemodialysis Patients with Critical Limb Ischemia After Isolated Infrapopliteal Balloon Angioplasty from the J-BEAT Registry Masatsugu Nakano et al TCT-570. Six-Month Outcomes of Prospective, Randomized CALCIUM 360 Study Demonstrate the Advantages of Plaque Modification with the Orbital Technology vs. Treatment with Balloon Angioplasty in Patients with Critical Limb Ischemia Nicolas W. Shammas et al TCT-571. Transvenous Intravascular Ultrasound-Guided Endovascular Treatment of Chronic Total Occlusion of a Lower Extremity Artery: A Novel Strategy Yasuhiro Takahashi et al TCT-572. Percutaneous Abdominal Aortic Aneurysm Repair: Methods and Initial Outcomes from the First Prospective, Multicenter Trial Zvonimir Krajcer et al TCT-573. Long-term Mortality After Aortic Dissection in the Community: Results from the Kaiser Permanente Registry of Aortic Dissections (KP-RAD) Cuong Lam et al TCT-574. Dexamethasone Infusion to the Adventitia to Enhance Clinical Efficacy After Femoropopliteal Revascularization: A Firstin-Man Study Christopher D. Owens et al TCT-575. Thoracic Endovascular Aortic Repair for Acute Type A Dissection: A Computational and Anatomic Analysis of Technical Limitations for Available Devices Sam Chitsaz et al TCT-576. Use of Orbital Treatment in a High-Volume Clinical Practice Modifies Noncompliant Plaque to Deliver Durable Long-term Results Prakash Makam et al The World’s Premier Interventional Experience TCT2011 TCT-579. A New Concept of Stent: The Multilayer Stent First-in-Human Study in Peripheral Aneurysms Michel Henry et al TCT-580. Clinical Evaluation of the IN.PACT Drug-Eluting Balloon for Treatment of Femoropopliteal Arterial Disease: Twelve-Month Results from a Multicenter Italian Registry Antonio Micari et al TCT-581. Drug-Eluting Balloon for Below-the-Knee Angioplasty Evaluation: The DEBATE-BTK Study Francesco Liistro et al TCT-582. Endovascular Therapy of Common Femoral Arterial Disease Philip B. Dattilo et al TCT-583. Pathologic Features of Atherosclerotic Plaques Retrieved by Excision and Relevant Biomarkers for the Risk Stratification of Peripheral Artery Disease Fumiyuki Otsuka et al TCT-584. Para-Millennium High-Risk AAA Saga: A Clinical Dilemma But Is Not a Major Concern for the Endovascular Specialist Niamh Hynes et al TCT-585. Usefulness of the Novel Ultrasonography “Vascular Elastography” for Endovascular Therapy Hideyuki Takimura et al TCT-586. Catheter-Based Renal Sympathetic Denervation: Chronic Preclinical Evidence for Renal Artery Safety Marian K. Rippy et al TCT-591. A New Concept of Stent: The Multilayer Stent: First-in-Human Study in TAA and AAA Michel Henry et al TCT-592. Antibiotic-Bonded Aortic Graft for Prevention of Vascular Graft Infection Ibrahim Aboshady et al TCT-593. Relationship Between Novel Angiographic Endpoint of Endovascular Therapy and Clinical Result of Patients with Critical Limb Ischemia Makoto Utsunomiya et al TCT-594. Clinical Outcomes Using the Viabahn Stent Graft in Complex Femoropopliteal Lesions Peter Mohr et al TCT-595. One-Year Clinical Outcomes of MISAGO2 the Large Multicenter Study with Misago the New Self-Expanding Nitinol Peripheral Stent: Final Results Karl-Ludwig Schulte et al TCT-596. Factors Related to the Failure of Limb Salvage Following Endovascular Therapy in Patients with Critical Limb Ischemia Shin Okamoto et al TCT-597. Utilization of Imaging Modalities Prior to Amputation Among Patients with Peripheral Arterial Disease or Diabetes: A Nationwide Study Sumeet Subherwal et al TCT-598. Paradigm Shift in Ruptured AAA (RAAA) Management: Twelve-Year Experience in a Tertiary Referral Center of Endovascular Repair of RAAA (REVAR) vs. Open Repair (OR) Sherif Sultan et al TCT-599. Results of the US IDE Study of the Wildcat Catheter (CONNECT) John P. Pigott et al TCT-587. Acute Limb Ischemia in an Interventional Cardiology Practice Jeremy R. Warner et al TCT-600. The OCELOT Catheter for Long SFA Occlusions: Six-Month Follow-up R. Stefan Kiesz et al TCT-588. Risk Stratification in Abdominal Hybrid-Procedures (AHP) of TAAA: Which Scoring System Fits Best? Michael Gawenda et al TCT-601. Midterm Outcomes of SMART Self-Expanding Nitinol Stent Implantation for Chronic Total Occlusion of Superficial Femoral Artery Yasunari Sakamoto et al TCT-589. New Concept for Percutaneous Peripheral Intervention to Calcified Lesion: Aggressive Wire Recanalization in Calcified Atheroma and Dilatation (ARCADIA) Technique Daisuke Yokota et al Coronary Angiography and CTA TCT-602. Matrix Metalloproteinases Can Predict the Progression of Nonculprit Lesions Konstantinos Toutouzas et al TCT-603. Incidence, Morphological Pattern, and Time Course of Peristent Contrast Staining Haruki Eguchi et al TCT-604. Reduced Coronary Angioplasty Screening Frame Rate Significantly Lowers Radiation Exposure Without Affecting Image Quality or Patient Outcome Sam J. Wilson et al TCT-605. Angiographic Progression of Coronary Atherosclerosis in Culprit and Nonculprit Lesion Seung pyo Hong et al TCT-606. Radiation Dose Reduction During Radial Cardiac Catheterization: Evaluation of a New Absorption Shielding Drape Jeffrey Nadelson et al - N o v e m b e r 8 , 2 0 11 TCT-578. Mechanical Thrombectomy in Treatment of Limb Ischemia: Interim Results of a Prospective Multicenter Registry Peter Soukas et al TCT-590. Endovascular Peripheral and Visceral Aneurysms Repair with Cardiatis Multilayer Flow Modulator: Results at 6- and 12-Month Follow-up Maria Antonella Ruffino et al Tuesday TCT-577. TEVAR in 2011: Worldwide Experience with a Conformable Graft: Does the Combination of Flexibility and Radial Strength Lead to Positive Outcomes in Thoracic Pathologies? Zvonimir Krajcer T r a n s c at h e t e r Cardiovascular Therapeutics TCT-607. Patients Radiation Doses in a Contemporary Cohort of Patients Undergoing Interventional Cardiology Procedures Juan Manuel Nogales-Asensio et al TCT-608. Plasma Levels of Haptoglobin Is Elevated in Patients with Coronary Artery Disease Ching-Wei Lee et al TCT-609. Safety and Feasibility of the Magnetic Positioning System (MPS) for Percutaneous Coronary Intervention Carl J. Schultz et al TCT-610. What Is the Likelihood That an Individual Who Has a Normal Coronary Angiogram After the Age of 40 Will Develop Significant Coronary Artery Disease? Siddhartha Rao et al TCT-611. Radiation Exposure and Diagnostic Efficacy in Dual-Axis Rotational Coronary Angiography vs. Standard Coronary Angiography Gerardo Nau et al TCT-612. Feasibility of Myocardial Perfusion Assessment by the Novel C-Arm CT Angiography Harald Rittger et al TCT-613. Histologic Features of Advanced Coronary Plaques Predict the Delineation of the of Napkin Ring Sign in Coronary CT Angiography Harald Seifarth et al TCT-614. Prognostic Role of Coronary Artery Plaque in Patients with Suspected Coronary Artery Disease Using Multislice Computed Tomography (PREDICT) Sung Uk Kwon TCT-615. The New 320-Row Computed Tomography with Lower Radiation Exposure to Rule Out Coronary Artery Disease in Patients with Atrial Fibrillation Francesco Pelliccia et al www.tctconference.com 73 Tuesday, November 8 TCT-616. Relationship Between Angiographic Dynamic and Densitometric Assessment of Myocardial Reperfusion and Survival in Patients with Acute Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention: The HORIZONS-AMI Trial Sorin J. Brener et al TCT-617. Noninvasive Assessment of In-Stent Restenosis by High-Definition Computed Tomography Coronary Angiography with New Gemstone Detector Hirotsugu Mihara et al TCT-618. Quantitative Monitoring of Atherosclerotic Plaque Development and Characterization by Flat-Panel Computed Tomography Ibrahim Aboshady et al TCT-627. Risk Evaluation of Distal Embolization During Percutaneous Coronary Intervention by Angioscopy and Virtual Histology Intravascular Ultrasound Imaging Koshi Matsuo et al TCT-628. Relative Dose and Vascular Response After Resolute Zotarolimus-Eluting Stent Implantation: A Dosimetric 3-D-Intravascular Ultrasound Study Hideki Kitahara et al TCT-629. Comparison of Optical Coherence Tomography and Histopathology Findings Following Paclitaxel-Coating Balloon in Porcine In-Stent Stenosis Model Arihiro Sumida et al TCT-639. Plaque Morphology with Optical Coherence Tomography and Biomarkers Kohei Koyama et al TCT-640. Totally Occluded Infarct-Related Arteries in STEMI Patients Are Associated with More Calcification and Myonecrosis Sang-Wook Kim et al TCT-630. Does Measurement of Serum 1.5-Anhydroglucitol (1.5-AG) Level Be Able to Predict the Presence of Coronary Plaque? Suguru Murase et al TCT-641. What Is the Optimal Blood Pressure for Coronary Plaque regression in Hypertensive Patients? ALPS-J Subanalysis Akihisa Nishino et al Intravascular Imaging: IVUS, OCT, Spectroscopy, and Other TCT-631. Correlation Between Modification in Plaque Composition and Changes in Vascular Geometry at the Edges of Bare Metal and Drug-Eluting Stents Jose De Ribamar Costa et al TCT-642. The Impact of Endothelial Wall Shear Stress on Vulnerable Plaque Growth Wang-Soo Lee et al TCT-621. Long-term (Five Years) Serial In Vivo Evaluation of Chronic Stent Recoil after Drug-Eluting Stent Implantation: Does It Exist? Carlos A. Collet et al TCT-632. Impact of Stent Platform of Paclitaxel-Eluting Stents: Detailed Assessment of Neointimal Distribution by Optical Coherence Tomography Hiromasa Otake et al TCT-622. The Clinical Impact of Intravascular Ultrasound in Patients Undergoing Implantation of Drug-Eluting Stents in the Left Main Abdi Jama et al TCT-633. Stent Recoil and Angiographic Outcome in Drug-Eluting Stents. Results of the STEREO-DES Pilot Study Javier Escaned et al TCT-619. Direct Mapping and Digital Reconstructions of the Human Cardiac Venous Anatomy Julianne Eggum et al TCT-623. Intravascular Ultrasound and Optical Coherence Tomography Comparison of the Self-Expanding Sideguard Stent in the Sidebranch vs. a Balloon-Expandable Drug-Eluting Stent in the Main Vessel: Follow-up Results of Bifurcation Lesions Treated with this Novel Device Shixin Ma et al TCT-624. Comparison by Optical FrequencyDomain Imaging of Paclitaxel-Eluting Stents and Everolimus-Eluting Stents Implanted in One Coronary Artery in One Procedure: 12-Month Follow-up Evaluation Jose M. De la Torre Hernandez et al TCT-625. Tissue Coverage and Neointimal Hyperplasia of Overlap vs. Nonoverlap Segments in Drug-Eluting Stents 9 to 13 Months After Implantation: In Vivo Assessment with Optical Coherence Tomography Juan Luis Gutiérrez-Chico et al TCT-634. Impact of Peristent Plaque Change After Drug-Eluting Stents Implantation: Comparison Between Zotarolimus-Eluting Stents and Paclitaxel-Eluting Stents Yoshitaka Muraoka et al TCT-635. Distorted Balloon Shape During Predilatation Before Stenting Predicts Stent Underexpansion Shinichiro Yamada et al TCT-636. Frequency and Distribution of Thin-Capped Fibroatheroma in the Left Main Coronary Artery: A Virtual Histology Intravascular Ultrasound Analysis Sang-Wook Kim et al TCT-637. In Vivo Characterization of Bioresorbable Vascular Scaffold Strut Interfaces Using Optical Coherence Tomography with Gaussian Line Spread Function Analysis Alexander Sheehy et al TCT-626. Relation Inflammatory Status and Cholesterol Metabolism to Coronary Plaque Vulnerability Kenya Nasu et al 74 TCT-638. Changes In Quantitative IVUSDerived Hyperechogenicity of EverolimusEluting Bioresorbable Vascular Scaffold In Relationship to Coronary Arterial Remodeling and Baseline Morphology of the Scaffolded Plaque: Insight from ABSORB Trial Salvatore Brugaletta et al program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s TCT-643. Six-Month Follow-up Data of Orbital Atherectomy System for the Treatment of De Novo Calcified Coronary Lesions (ORBIT I Trial) Keyur Parikh et al TCT-644. Detection of Lipid Core Coronary Plaques by Serial Intracoronary Imaging with a NIRS Catheter in Coronary Arteries of Atherogenic Swine Oana Sorop et al TCT-645. Debulking by Rotational Atherectomy with a Modified Protocol Increases Long-term Survival Georg Gaul et al TCT-646. Excimer Laser Lesion Modification to Expand Nondilatable Stents (The ELEMENT Registry) Azeem Latib et al TCT-647. Two-Year Follow-up Data of Orbital Atherectomy System for the Treatment of De Novo Calcified Coronary Lesions: A Single-Center Experience Keyur Parikh et al TCT-648. Evidence of Late Neointimal Hyperplasia Formation After Five Years of Different Generations Drug-Eluting Stents Carlos A. Collet et al TCT-649. Classification of Atherosclerotic Plaques Using Depth Resolved Spectral Analysis of Optical Frequency Domain Imaging Datasets Christine P. Fleming et al TCT-650. In Vivo Tissue Characterization of Coronary Lipid Plaques: Comparison of Optical Coherence Tomography and Near-Infrared Spectroscopy Brijeshwar Maini et al The World’s Premier Interventional Experience TCT2011 TCT-672. Relation Between Microalbuminuria and Vulnerable Plaque Components in Patients with Acute Coronary Syndrome and with Diabetes Mellitus: Virtual HistologyIntravascular Ultrasound Analysis Young Joon Hong et al TCT-662. Impact of Post-interventional Minimal Stent Area on Angiographic Restenosis After Zotarolimus and Everolimus-Eluting Stent implantation Hae-Geun Song et al TCT-673. Optical Coherence Tomography Characteristics of Coronary Plaques with Ultrasonic Attenuation Takashi Kubo et al TCT-653. Quantitative and Qualitative Changes of Neointimal Tissue in DrugEluting Stents: Serial (Nine Months and Two Years) Observation Using Intracoronary Optical Coherence Tomography Jung-Sun Kim et al TCT-663. Relationship Between Plaque Composition Assessed with Radiofrequency IVUS and Clinical Outcomes in Patients with Acute Coronary Syndromes and Diabetes Mellitus or Metabolic Syndrome: The PROSPECT Trial Steven P. Marso et al TCT-654. Quantitative Multimodality Imaging Analysis of a Fully Bioresorbable Scaffold: A Head-to-Head Comparison Between QCA, IVUS, and OCT Juan Luis Gutiérrez-Chico et al TCT-664. Syntax Score Reflects Coronary Plaque Characteristics Assessed by Integrated Backscatter Intravascular Ultrasound Hideaki Ota et al TCT-655. Effectiveness of Thromboaspiration Therapy in Patients with Acute Myocardial Infarction: An Optical Coherence Tomography Study Takashi Kubo et al TCT-665. Association Between Novel 3-D Geometrical Lesion Analysis and Indicators of Plaque Vulnerability Danny Dvir et al TCT-656. Relation Between the Multivessel Disease and Culprit Lesion Morphology in Acute Coronary Syndrome: An Optical Coherence Tomography Study Kenichiro Saka et al TCT-657. Assessment of Atherosclerosis at Coronary Bifurcations with Multislice Computed Tomography and Intravascular Ultrasound-Virtual Histology Stella-Lida Papadopoulou et al TCT-658. Differential Healing Response in Acute Coronary Syndrome vs. Stable Coronary Artery Disease Patients Five Years Following Early Generation DES Implantation: An Optical Coherence Tomography Study Lorenz Raber et al TCT-659. Natural History of Optical Coherence Tomography-Detected Edge Dissections 12 Months Following Drug-Eluting Stent Implantation Maria D. Radu et al TCT-660. In Vivo Findings of Tissue Characteristics in High-Risk Coronary Artery Plaques Using iMap IVUS Karlis Trusinskis et al TCT-666. Near-Infrared Spectroscopic Assessment of Lipid Core Plaque Changes After Coronary Artery Stenting Diaa A. Hakim et al TCT-667. Acute Effects of Nicardipine and Esmolol on the Cardiac Cycle, Hemodynamic and Endothelial Shear Stress in Patients with Unstable Angina Pectoris and Moderate Coronary Stenosis: Results from a Single-Center, Randomized Study Shao-Liang Chen et al TCT-674. Automated 3-D Detection of Intracoronary Stent Struts in Optical Coherence Tomography Images Nico Bruining et al TCT-675. In Vivo Assessment of Neoatherosclerosis After Sirolimus-Eluting Stent Implantation: Comparisons of Serial Optical Coherence Tomography Findings Between Early and Late Follow-up Amane Kozuki et al TCT-676. Comparison of Virtual Histology and OCT in the Tissue Characterization of In-Stent Restenosis Koichi Hanada et al TCT-677. Optical Coherence Tomography Analysis for Restenosis of EverolimusEluting Stents in Comparison with Bare Metal Stents and Paclitaxel-Eluting Stents Shoichi Kuramitsu et al TCT-678. Comparative Study in Two Institutions Between IVUS and Pressure Wire in the Assessment of Intermediate Lesions Jose M. De la Torre Hernandez et al TCT-679. The Relationship Between Long-term Clinical Outcomes and Serial Atheroma Changes by Volumetric Intravascular Ultrasound Atsushi Hirohata et al TCT-668. New Insights into the Coronary Artery Bifurcation: Hypothesis Generating Concepts Utilizing 3-D Optical Frequency Domain Imaging Vasim Farooq et al TCT-680. Extent, Characterization, and Clinical Implications of Untreated Lesions with High Plaque Burden After Successful Percutaneous Coronary Intervention: A PROSPECT Substudy John A. McPherson et al TCT-669. Long-term Follow-up of a Large Cohort of Patients with Intermediate Lesions Assessed with IVUS Jose M. De la Torre Hernandez et al TCT-681. Volumetric Intravascular Ultrasound Assessment of Mechanisms and Results of Stent Expansion in Heart Transplant Patients Elias Sanidas et al TCT-670. Uniform Vessel Healing After Everolimus-Eluting Stent Implantation: Detailed Comparison with Paclitaxel-Eluting Stent by Optical Coherence Tomography Tsuyoshi Osue et al TCT-682. Impact of Plaque Composition on Postprocedural Myocardial Injury During Stent Implantation: A Meta-analysis Jae-Sik Jang et al TCT-671. Can Metabolic Syndrome Predict the Vulnerable Plaque in Patients with Stable Angina Pectoris? Virtual HistologyIntravascular Ultrasound Analysis Min Goo Lee et al - N o v e m b e r 8 , 2 0 11 TCT-652. In Vivo Distribution of Lipid Core Containing Plaque According to Distance from the Ostium by Near-Infrared Spectroscopy in Noncuprit Coronary Arteries Salvatore Brugaletta et al TCT-661. Relation Between Poststenting Peristent Plaque Components and Late Acquired Drug-Eluting Stent Malapposition: Virtual Histology-Intravascular Ultrasound Analysis Young Joon Hong et al Tuesday TCT-651. Assessment of the Bioresorption Process Utilizing Intravascular UltrasoundDerived Echogenicity Analyses and Vasomotion Testing of the ABSORB Bioresorbable Everolimus-Eluting Vascular Scaffold: A Substudy of the ABSORB Cohort B Trial Jung Ho Heo et al T r a n s c at h e t e r Cardiovascular Therapeutics TCT-683. Prediction of Distal Embolization During Percutaneous Coronary Intervention for Unstable Plaques with Grayscale and Integrated Backscatter Intravascular Ultrasound Daisuke Morisawa et al www.tctconference.com 75 Tuesday, November 8 TCT-684. Detection of >0.4 mm of Minimal Intimal Thickness During Routine Intracoronary Ultrasound Studies Without a Baseline Study Correlates Strongly with Total Death and Adverse Outcomes in Cardiac Transplant Patients Reza Arsanjani et al TCT-685. Neointimal Hyperplasia and Peristent Vascular Remodeling After Implantation of Everolimus-Eluting Stent vs. Sirolimus-Eluting Stent: Intravascular Ultrasound Results from EXCELLENT Study Young-Guk Ko et al TCT-686. Optical Coherence Tomography Assessment of Neointimal Coverage According to the Presence or Absence of Malapposed Struts After Drug-Eluting Stent Implantation Byeong-Keuk Kim et al TCT-687. Neointimal Coverage of EverolimusEluting Stent at One, Two, and Three Months Follow-up: Evaluation by Optical Coherence Tomography Takao Shimohama et al TCT-688. Two-Year Long-term Follow-up Optical Coherence Tomographic Findings Compared with Nine Months After Implantation of Everolimus-Eluting Stents Jun-Won Lee et al TCT-689. The Utility of Three Primary Prevention Scoring Systems (Framingham, PROCAM, and SCORE) in Predicting Future Events in Patients with Acute Coronary Syndromes: The PROSPECT Trial Jung-Won Suh et al TCT-690. Age- and Sex-Related Plaque Composition of Nonculprit Lesions in Patients with Acute Coronary Syndromes: The PROSPECT Study Juan Ruiz GarcÌa et al TCT-691. Contributions of Mechanical Factors and Biologic Response to Sirolimus-Eluting Stent Thrombosis: Final IVUS Results from the RESTART Registry Teruyoshi Kume et al Physiologic Lesion Assessment TCT-697. Percent Stenosis Is a Weak Predictor of Fractional Flow Reserve: Insights from a French Multicenter Registry (R3F) Eric Van Belle et al TCT-698. Optimal Cutoff Value of Coronary Flow Velocity to Predict Functional Recovery in TIMI-3 Reperfused Acute Myocardial Infarction Hiroyuki Hikita et al 76 program · TCT-699. Can Potentially Significant Competitive Flow Be Identified at the Time of CABG? T. Bruce Ferguson et al TCT-700. Influence of Cardiac Contractility on Functional and Anatomical Diagnostic Endpoints Under Concomitant Microvascular Dysfunction in a Porcine Model Srikara Viswanath Peelukhana et al TCT-701. Assessment of Lesion Length on Fractional Flow Reserve in Intermediate Coronary Lesions Hiroaki Takashima et al TCT-702. A Comparative Study Between Intravenous and Intracoronary Administration of High Doses Adenosine for Fractional Flow Reserve Measurements in the “FAME” Era Jose M. Cubero et al TCT-703. Functional Assessment of Jailed Sidebranches in Coronary Bifurcation Lesions Using Fractional Flow Reserve Jung-Min Ahn et al TCT-704. Improving Syntax Score with Fractional Flow Reserve Marco Novara et al TCT-705. Intravascular Ultrasound Characteristics in Patients with Intermediate Coronary Lesions and Borderline Fractional Flow Reserve Measurements Hyoung-Mo Yang et al TCT-706. New Perspective on the Fractional Flow Reserve: High Predictive Value of Baseline Pd/Pa During Intracoronary Pressure Wire Study June-Hong Kim et al TCT-707. The Difference of Lesion Location Affects Physiological Severity in Intermediate Coronary Lesions Hiroaki Takashima et al TCT-708. Virtual Coronary Physiology and Anatomy Derived from Rotational Angiography: The First Step Paul D. Morris et al TCT-709. Contemporary Patterns of FFR and IVUS Use Among Patients Undergoing PCI in the United States: Insights from the NCDRÆ Philip B. Dattilo et al TCT-710. Impact of FFR on Global and Individual Decision of Coronary Revascularization: Insights from a Large Multicenter Registry Eric Van Belle et al T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Congenital Heart Disease and Acquired Structural Defects TCT-711. Large Devices for Transcatheter Closure of Atrial Septal Defects in Adult Patients: the REPERA Multicenter Registry Felipe Hernandez et al TCT-712. Percutaneous Paravalvular Leak Closure Abates Heart Failure Symptoms, Reduces NT-proBNP Plasma Concentration and Left Ventricle Size Grzegorz Smolka et al TCT-713. Safety and Performance of a New Ceramic-Coated Double-Disc Patent Foramen Occluder: One- and Six-Month Follow-up Tina Edwards-Lehr et al TCT-714. Percutaneous Transcatheter Pulmonary Valve Implantation Induces a Reduction of B-Type Natriuretic Peptide at 30 Days Joelle Kefer et al TCT-715. Transcatheter Occlusion of the Patent Ductus Arteriosus with the New ADO II Amplatzer Device Norberto Herrera Guemez et al TCT-716. Complications Leading to Explantation of PFO Closure Devices: A Multicenter Review Swarnendra Verma et al TCT-717. Comparison of Long-term Follow-up After Endovascular Stent Placement Between Patients with Native Coarctation or Postsurgical Recoarctation Maria Giulia Gagliardi et al TCT-718. Preclosure of Large-Sized Venous and Arterial Sheath Access Sites in Adults Undergoing Transcatheter Structural Interventions Tahir Hamid et al TCT-719. A New Anatomical Classification of the Left Atrial Appendage Based on Carto/ CT/MR: Implications for the Implantation of Left Atrial Apppendage Closure Device Jose R. Lupez-Minguez et al TCT-720. Percutaneous Closure of the Left Atrial Appendage with the Amplatzer Cardiac Plug: Initial Latin American Experience AnÌbal A. Damonte et al TCT-721. Thrombi on the Amplatzer Cardiac Plug After LAA Occlusion: Evaluation of Potential Echo Risk Factors Börn Plicht et al TCT-722. Single-Center Experience of Left Atrial Appendage Closure. Role of Carto/CT/ MR in the Selection of Device Size Jose R. Lupez-Minguez et al The World’s Premier Interventional Experience TCT2011 TCT-725. Interventional Perspective of Tricuspid Regurgitation: Heterotopic Percutaneous Valve Implantation from Preclinical Trials to First-in-Man Application Alexander Lauten et al TCT-726. Transcatheter Laser Irradiation in the Treatment of Migraine Ivan V. Maksimovich Valvular Heart Disease: Aortic TCT-727. Most Patients Fulfill the Access Way Criteria in Transcatheter Aortic Valve Implantation Daniel John et al TCT-728. Sutureless Implantation of a Expandable Mitral Stent-Valve Prosthesis in Acute Animal Model Jose L. Navia et al TCT-729. Reduced Incidence of Bleedings, Vascular Complications, and 30-Day Mortality with the Sapien Novaflex System: Results from a Single-Center Transfemoral TAVI Registry Giovanni Sorropago et al TCT-730. Transcranial Doppler Analysis of Embolic Events During Transcatheter Aortic Valve Implantation William T. Brinkman et al TCT-731. Clinical and Functional Outcome After Transapical Aortic Valve Implantation Using the JenaValve AVR System: One-Year Results of the First-in-Man Study Ardawan J. Rastan et al TCT-732. Transcatheter Aortic Valve Replacement with a Self-Expandable Bioprosthesis Performed Without Balloon Valvuloplasty: Comparative Results in a Consecutive Series of Patients Dimytri A. Siqueira et al TCT-733. The Ratio Between Bioprosthesis and CT-Measured Mean Annulus Diameter Predicts Significant Postprocedural Aortic Regurgitation in Transcatheter Aortic Valve Implantation Kentaro Hayashida et al TCT-734. Predictors and Clinical Outcome of Patients with Acute Kidney Injury Following Transcutaneous Aortic Valve Replacement Israel M. Barbash et al TCT-736. Impact of CT-Guided Bioprosthesis Sizing on Postprocedural Aortic Regurgitation in Transcatheter Aortic Valve Implantation Kentaro Hayashida et al TCT-737. Does the STS-PROM Score or the Logistic EuroScore Predict Outcomes Following Transcatheter Aortic Valve Replacement at 30 Days: The Milan Experience Gill L. Buchanan et al TCT-738. Geometry of the Edwards SAPIEN XT Valve as Assessed by Multidetector Computed Tomography Alex B. Willson et al TCT-739. Midterm Stability and Hemodynamic Performance of a Transfemorally Implantable Nonmetallic, Retrievable, and Repositionable Aortic Valve in Patients with Severe Aortic Stenosis: Two-Year Results of the Direct Flow Medical Valve Klaudija Bijuklic et al TCT-740. Does Left Atrial Diameter in Patients with Severe Aortic Stenosis Have a Clinical Impact on Outcome? Camille Hauville et al TCT-747. Balloon Aortic Valvuloplasty as a Bridging Thearpy to Aortic Valve Replacement or Transcatheter Aortic Valve Implantation Michael Tempelhof et al TCT-748. Optimal Projection for Transcatheter Aortic Valve Implantation Determined from the Reference Projection Angles James A. Cockburn et al - N o v e m b e r 8 , 2 0 11 TCT-724. Percutaneous Closure of Multiple Paravalvular Leaks with Amplatzer Vascular Plug III Device: Single-Center Experience Jaime R. Dutary et al TCT-735. New Onset Atrioventricular Block After Corevalve Implantation Is Due to Direct Damage on the His-Bundle System Raquel del Valle et al Tuesday TCT-723. Percutaneous Pericardiocentesis vs. Surgical Pericardial Drainage in the Treatment of Symptomatic Pericardial Effusions: Recurrence and Complication Rates A. Garvey Rene et al T r a n s c at h e t e r Cardiovascular Therapeutics TCT-749. Efficacy and Safety of Transcatheter Aortic Valve Replacement: Northern Ireland Experience Ganesh Manoharan et al TCT-750. The STS-Score Outperforms the EuroSCORE in Predicting Short-term Outcome Following Transcatheter Valve Implantation but Does Not Predict Long-term Outcome Ralf Lehmann et al TCT-751. Outcome Comparison of Nontransfemoral Approaches for Transcatheter Aortic Valve Implantation Utilizing CoreValve Pak Hei Chan et al TCT-752. Comparison of Transcatheter Aortic Valve Implantation vs. Surgical Aortic Valve Replacement in a High-Risk Patient Population: A Propensity Score Analysis Lenard Conradi et al TCT-741. Candidates for Transcatheter Aortic Valve Replacement (TAVR): Fitting the Current PARTNERS Criteria? Michael J. Babcock et al TCT-753. In-Hospital Complications After Transcatheter Aortic Valve Implantation Revisited According to the Valve Academic Research Consortium Definitions Rutger-Jan Nuis et al TCT-742. Finite Element Analysis of Transcatheter Aortic Valve Implantation: Impact of Oversizing on Stent and Leaflet Stresses Ali Azadani et al TCT-754. B-Type Natriuretic Peptide Predicts Improvement of Left Ventricular Function and Clinical Outcome After Balloon Aortic Valvuloplasty Joelle Kefer et al TCT-743. Incidence, Timing, and Predictors of Valve Dislodgment During TAVI with the Medtronic Corevalve System Nicolas M. Van Mieghem et al TCT-755. Surgical vs. Transcatheter Aortic Valve Replacement with the Sapien XT Valve and NovoFlex Delivery System in High-Risk Patients with Severe Aortic Stenosis Azeem Latib et al TCT-744. Edwards-SAPIEN Valve Positioning During Transcatheter Aortic Valve Implantation: Multicenter Evaluation with Clinical and Anatomical Correlates Danny Dvir et al TCT-745. Reconsidering Outcomes After Transcatheter Aortic Valve Implantation Following the Valve Academic Research Consortium Definitions Moritz Seiffert et al TCT-746. Mortality Outcomes in 501 TAVI Patients Stratified According to Age Tertiles Matthias Kornek et al TCT-756. The Effects of Preexisting Significant Coronary Artery Disease Defined by QCA Analysis Upon Outcome After Transcatheter Aortic Valve Implantation Using the Edwards Bioprosthesis Muhammed Z. Khawaja et al TCT-757. Impact on the Need for Permanent Pacemaker Requirement After CoreValve Prosthesis Implantation with the New Accutrak Delivery Catheter System Antonio J. Munoz-Garcia et al www.tctconference.com 77 Tuesday, November 8 TCT-758. True Percutaneous Approach for Transfemoral Aortic Valve Implantation Using Prostar XL Device: Impact of the Learning Curve on Vascular Complications Kentaro Hayashida et al TCT-759. Geographic Variations In Transcatheter Aortic Valve Implantation Rates Across 14 European Countries Stuart Mealing et al TCT-760. Numerous Patients Fail the Aortic Annulus Criteria In Transcatheter Aortic Valve Implantation Daniel John et al TCT-761. Prognostic Impact of Permanent Pacemaker Implantation Among Patients with Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation Lutz Buellesfeld et al TCT-762. Predictive Factors and Prognostic Value of Periprocedural Myocardial Injury During Transcatheter Aortic Valve Implantation Ze Yie Yong et al TCT-763. Aortic Valve Calcium Scoring (AVCS) Is a Predictor of Significant Paravalvular Aortic Insufficiency in Transapical Aortic Valve Implantation Martin Haensig et al TCT-764. Transcatheter Aortic Valve Replacement: Outcome of Patients with Moderate or Severe Mitral Regurgitation Stefan Toggweiler et al TCT-765. Transcatheter Aortic Valve Implantation: Multicenter Study Evaluating the Clinical Outcomes of Patients with PARTNER Trial Exclusions Ronen Gurvitch et al TCT-766. Predictors of AVB After TAVR with Both Edwards and CoreValve THV System Marco Mussardo et al TCT-767. Gender Differences in Patients Undergoing Transcatheter Aortic Valve Implantation with the Medtronic CoreValve System Yacine Elhmidi et al TCT-768. Transcatheter Aortic Bioprosthesis Embolization: Technical Aspects and Midterm Follow-up Marco Barbanti et al TCT-769. Requirement of Small Size of Prosthetic Aortic Valve in Asian Population: Implication to Select Valve Size for Transcatheter Aortic Valve Implantation in Elderly Mike Saji et al TCT-770. FRANCE II: French Registry Aortic National CoreValve and Edwards Registry II Martine Gilard et al 78 program · TCT-771. Expanded Anatomic Suitability of Current Generation Transcatheter Aortic Balloon-Expandable Prostheses Massimo Napodano et al TCT-783. Transaortic Access for Transcatheter Aortic Valves Implantation: Single-Center Experience Giuseppe Bruschi et al TCT-772. Clinical Outcome Following Transcatheter Aortic Valve Implantation in Patients with Impaired Left Ventricular Systolic Function Robert M. van der Boon et al TCT-784. Multislice Computed Tomography: New Gold Standard for Valve Sizing and Prevention of Aortic Regurgitation in Patients Referred for Transcatheter Aortic Valve Implantation? Mariam Samim et al TCT-773. Prediction of Optimal Deployment Projections in Transcatheter Aortic Valve Replacement: Angiographic 3-D Reconstruction of the Aortic Root vs. Multidetector Computed Tomography Ronald K. Binder et al TCT-774. Feasibility and Safety of Transaortic Transcatheter Aortic Valve Implantation In Patients with Previous Cardiac Surgery Using the Edwards SAPIEN Bioprosthesis Muhammed Z. Khawaja et al TCT-785. Is “Porcelain Aorta” a Real Contraindication for Transaortic Transcatheter Aortic Valve Replacement? Vinnie Bapat et al TCT-786. Beyond the Short-term: Clinical Outcome and Valve Performance Two Years After Transcatheter Aortic Valve Implantation in 227 Patients Sabine Bleiziffer et al TCT-775. Improved Procedural Results After CoreValve Implantation with the New AccuTrak Delivery System Emmanuel Chorianopoulos et al TCT-787. Australian and New Zealand Source Registry: Edwards Sapien Transcatheter Aortic Valve Replacement: 30-Day Outcomes Darren Walters et al TCT-776. Outcome of Residual Paravalvular Aortic Regurgitation (PAR) After Transfemoral Aortic Valve Implantation (TAVI) and Importance of Hemodynamic Assessment P. C. Patsalis et al TCT-788. Three-Month Results of the JenaValve Multicenter Study Evaluating a Second Generation Transcatheter Aortic Valve Implantation System Hendrik Treede et al TCT-777. Preprocedural Predictors of Early and Midterm Mortality in Patients Treated with Transcatheter Aortic Valve Implantation: A Single-Center Experience. Kirsten Boerlage-van Dijk et al TCT-789. Clinical Profile and Outcome Correlates in Patients with Severe Aortic Stenosis at High-Surgical Risk: Prospective Evaluation According to Treatment Assignment Danny Dvir et al TCT-778. Myocardial Injury and Electrocardiographic Changes Following Transcatheter Aortic Valve Implantation Manolis Vavuranakis et al TCT-779. Predictive Factors of Major VARC Vascular Complications Following Transfemoral Transcatheter Aortic Valve Implantation Ilyes Kharrat et al TCT-780. Accuracy of Intracardiac Echocardiography for Aortic Root Assessment in Patients Candidated to Transcatheter Aortic Valve Implantation Marco Barbanti et al TCT-790. Late Occurrence of Bradyarrhythmias After TAVI with the CoreValve Aortic Bioprosthesis Emmanuel Chorianopoulos et al TCT-791. Transient Increase in Pressure Gradient After TAVI: A Question of Dual Antiplatelet Therapy? Fadi Al-Rashid et al TCT-792. A Low-profile Highly Conformable Sealing Technology for Transcatheter Heart Valves Martin Ng et al TCT-793. The Importance of Aortic Annular Area and Eccentricity on Balloon Expandable Aortic Valve Sizing, Geometry, and Paravalvular Regurgitation Alex B. Willson et al TCT-781. 3-D Multislice Computed Tomography to Predict Annulus Plane Angulation and C-Arm Positioning in Patients Referred for TAVI: Benefit on Safety Procedural Outcome Mariam Samim et al Valvular Heart Disease: Mitral TCT-782. Timing and Potential Mechanisms of New Conduction Abnormalities During the Implantation of the Medtronic CoreValve System in Patients with Aortic Stenosis Rutger-Jan Nuis et al TCT-795. MitraClip for Patients with Mitral Regurgitation Who Are Ineligible for Surgical Repair or Replacement: A UK-Based Cost-Utility Analysis Stuart Mealing et al T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 TCT-798. Long-term Follow-up of Mitral Valvuloplasty with Single Balloon: Independent Predictors of Survival and Event-Free Survival Edison S. Peixoto et al TCT-799. Functional vs. Degenerative Mitral Regurgitation in Patients Not Amenable to Surgery Undergoing MitraClip Treatment Stephan Baldus et al Coronary Interventions TCT-1001. The Use of Multimodality Imaging Optimizes Primary PCI Strategy in Stent Thrombosis Paul Rees et al TCT-1002. Bailout Application of Five-in-Six Double-Catheter in Transradial Coronary Intervention Qi Zhang et al TCT-1003. A Self-Expandable Coronary Stent System to Treat Complex Coronary Stenosis Complicated by Post-Stenotic Aneurysm: An Optical Coherence Tomographic EvidenceBased Case Report Salvatore Geraci et al TCT-800. Quality-of-Life Changes in High-Risk Patients After Percutaneous Mitral Valve Repair with MitraClip Maurizio Taramasso et al TCT-1004. Percutaneous Closure of Secundum Atrial Septal Defect in Left Ventricular Assist Device Recipient with Hypoxia and Right-to-Left Intraatrial Shunt Ethan Korngold et al TCT-801. The Impact of Commissural Morphology on Clinical Outcome in Patients Undergoing Percutaneous Balloon Mitral Valvuloplasty Mohamed A. Sadaka et al TCT-1005. Use of a Novel Stent Delivery Device for Severe Multivessel Diffuse and Chronic Disease Bruno del Blanco et al TCT-802. MitraClip Treatment of Functional Mitral Regurgitation in Patients Not Amenable to Surgery Volker Rudolph et al TCT-803. Changes in Platelet, Coagulation, Fibrinolytic Activities in Mitral Stenosis After Percutaneous Mitral Valvotomy: Role of Hemodymamic Changes and Systemic Inflammation Hosam Hasan-Ali et al TCT-804. Effectiveness of Percutaneous Reduction of Significant Mitral Regurgitation of Functional Etiology in High Surgical Risk Patients Michael Argenziano et al TCT-805. Tissue-Doppler Assessment of the Changes in Longitudinal Left and Right Ventricular Functions After Percutaneous Mitral Valvotomy Hosam Hasan-Ali et al TCT-806. Acute Hemodynamic Changes After Percutaneous Mitral Valve Repair Oliver Gaemperli et al TCT-1006. Only One Radial Artery Access for Retrograde PCI Bin Zhang et al TCT-1007. One Stage Unprotected Left Main and Multiple Vessel Angioplasty Alejandro Fernandez et al TCT-1008. A Case of Treatment for Proximal Left Anterior Descending Artery Chronic Total Occlusions Because of Unsuccessful Intervention via Left Internal Thoracic Artery to Left Anterior Descending Bypass Graft Interfered by Severe Stenosis of Nearby Graft Anastomosis Ryo Gotoh et al TCT-1009. Unusual Case of Coronary-Cameral Fistula with Failure of Surgical Ligation and Successful Outcome with Transradial Coil Embolization Abdul Basit et al TCT-1010. Rewiring and Fixation of a Lost Stent in Proximal LCx Enno Boudriot et al TCT-1011. Left Main Bifurcation Reverse T Stenting with Rotablation of Diffuse LAD Lesion Ananthakrishna Ajith Pillai et al TCT-1012. Which Is the Culprit? Complex Revascularization in a 63-Year-Old Male with Previous Coronary Artery Bypass Grafting Presenting with Non-ST-Segment Elevation Myocardial Infarction Crochan O’Sullivan et al TCT-1013. Percutaneous Retrieval of Entrapped Partially Inflated Broken Coronary Angioplasty Balloon by Modified Fogarty Technique Girish Palleda et al TCT-1014. Stenting: Treatment of Dual Bifurcation Lesions in a Patient with Non-ST-Elevation Myocardial Infarction Kimberly Brayton et al - N o v e m b e r 8 , 2 0 11 TCT-797. Immediate Mitral Valve Area After Successful Percutaneous Mitral Valvuloplasty: A Simple Predictor of Restenosis at Long-term Follow-up Rodrigo Blanco et al Challenging Cases Video Abstracts Tuesday TCT-796. EVEREST II High Surgical Risk Cohort: Clinical Benefit by MR Grade in High Surgical Risk Patients One Year Following MitraClip Therapy Paul Grayburn et al T r a n s c at h e t e r Cardiovascular Therapeutics TCT-1015. Unpreventive Distal Embolism Even with Distal Protection Device Due to Massive Vulnerable Plaque in RCA Observed by MDCT, IVUS, OCT Taku Asano et al TCT-1016. Stent Catheter Break During Percutaneous Coronary Angioplasty: Managing an Iatrogenic Emergency Praveen Sreekumar et al TCT-1017. No Reflow in Case of PAMI of Anterior Wall MI with Distal LAD Total Occlusion After All Measures, Left with Pharmacotherapy with Established Flow After 2 Days Jayesh Prajapati et al TCT-1018. Stage Complete Revascularization of a Cardiogenic Shock Patient Under ECMO Support Hsiu-Yu Fang et al TCT-1019. Successful Retrieval of Entangled Stents Using Basket Device During LM PCI Hsiu-Yu Fang et al TCT-1020. Two Cases with Significant Coronary Stenosis Accompanied by De Novo Coronary Artery Aneurysm; Successful PCI with Stent In Stent Technique - Case 2 Cheol-Yoong Yu et al TCT-1021. Graft Stent Deployment and an Iatrogenic Coronary Arteriovenous Fistula Occurring in Percutaneous Coronary Intervention of Chronic Total Occlusion Lesion Sang-Ho Park et al TCT-1022. Left Anterior Descending Artery Rupture Resolution Diego Grinfeld et al TCT-1023. A Case of Septal Channel Perforation During Retrograde Approach for LAD CTO Rei Fukuhara et al www.tctconference.com 79 Tuesday, November 8 TCT-1024. Hybrid Single Stage Antegrade and Retrograde Procedure for Long Segment Chronic Total Occlusion In Dominant Circumflex Pravin Goel et al TCT-1025. A Thromboid Severe Calcification on Left Main Coronary Artery Yoshihide Fujimoto et al TCT-1026. Left Main PCI in an Elderly Male with 3-Vessel Coronary Disease and Severe LV Dysfunction H. Prabhakar Shetty et al TCT-1027. Multivessel PCI of a Right Coronary Artery Chronic Total Occlusion and an Unprotected Left Main Rajan Patel et al TCT-1028. Stent Treatment of an Aortocoronary Dissection During Percutaneous Coronary Intervention Juan Manuel Nogales-Asensio et al TCT-1029. Rescue of the Coronary Dissection, Identify the True Lumen via IVUS Guidance Chun-Yuan Chu et al TCT-1030. PCI of Left Main Coronary Artery After Successful TAVI (CoreValve) Matjaz Bunc et al TCT-1031. Retrograde RCA CTO Intervention via Ipsilateral Radial and Brachial Artery Approach Hsiu-Yu Fang et al TCT-1032. First Report of Successful Occlusion of Complex Coronary Arteriovenous Malformation by Using Cyanoacrylate-Based Synthetic Glue (Glubran 2) Emanuela de Cillis et al TCT-1033. Impella Support for Unprotected Left Main PCI in a Patient with a Large Aortic Aneurysm Philip Dattilo et al TCT-1034. Multiple Steps Revascularization with Twice Perforation and LM Dissection Hsiu-Yu Fang et al TCT-1035. Repeated Percutaneous Coronary Intervention for Recurrent Spontaneous Coronary Dissection in a Patient with Acute Myocardial Infarction During Postpartum Period Takashi Nakayama et al TCT-1036. A Case with Coronary Perforation which was Treated with Embolic Coils and Fibrin Glue Motoo Date et al TCT-1037. Wiring Trapping in Torturous and Calcified Lesion Feng-Yu Kuo et al 80 program · TCT-1038. Successful Treatment of Radial Artery Occlusion Using a Clearway Catheter and Balloon Angioplasty George Revtyak et al TCT-1039. Excimer Coronary Laser Atherectomy Applied with Guideliner Catheter Support: A Novel Strategy to Treat a Distal Balloon Uncrossable Coronary Stenosis Wissam Al Sahli et al TCT-1040. Getting There is Half the Fun: Recanalizing a Chronically Occluded Brachial Artery Prior to Treatment of an Acute Distal Left Main Bifurcation Lesion from the Right Radial Approach Ronald Caputo et al TCT-1041. Successfully Rescue of Guidewire Fracture in Coronary Collaterals During LAD CTO Intervention Hsiu-Yu Fang et al TCT-1042. Immediately Bilateral Approach for Saving LAD CTO Antegrade Wiring Perforation Hsiu-Yu Fang et al TCT-1043. The Iron Man: Multiple Interventions in an Elderly Patient Fadi Al-Rashid et al TCT-1044. Challenging Anterior Myocardial Infarction in a Young Woman Stuart Watkins et al TCT-1045. Two Cases with Significant Coronary Stenosis Accompanied by De Novo Coronary Artery Aneurysm: Successful PCI with Stent in Stent Technique - Case 1 Hyunjong Lee et al TCT-1046. Retrograde LM Bifurcation Dissection During CTO Intervention Feng-Yu Kuo et al TCT-1047. Wire Fishing for an Unexpectedly Deployed Stent Zu-Yin Chen et al TCT-1048. Two-Step Parallel Wiring for Chronic Total Occlusion Shinichi Furuichi et al TCT-1049. Guideliner for a Difficult Coronary Fistula Elchanan Bruckheimer et al TCT-1050. Detection of Plaque Shifting by Intracoronary Pressure Measurement During Left Main Intervention Zsolt Koszegi et al TCT-1051. Plaque Hunting: Multimodality Imaging Is Mandatory to Allow Target Lesion Identification in ACS Paul Rees et al T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s TCT-1052. Rotational Atherectomy Is Useful to Treat the Restenosis Lesion Due to Under-Expansion of Drug-Eluting Stent Implanted on Severe Calcified Lesion Daisuke Morisawa et al TCT-1053. Impacted Thrombus Within the Introducer Sheath During Thrombus Aspiration Young-Jin Youn et al TCT-1054. Coronary Embolization Following Inadequate Anticoagulation in a Patient with Prosthetic Mitral Valve Vineet Bhatia et al TCT-1055. Unusual Case of Left Main Embolization Following Surgery for Post PCI Mycotic Aneurysm Narenda Khanna et al TCT-1056. A Case of Transradial PCI Using Four-in-Six System for Tortuous RCA Lesion Setsuo Kumazaki et al TCT-1057. PCI to Chronic Total Occlusion of RCA, LAD, and Large LM Disease Bin Zhang et al TCT-1058. Rotational Atherectomy of Native LAD via LIMA Graft Aaron Wong et al Endovascular Interventions TCT-1059. Reuse of Occluded Ulnar Artery for Repeat Coronary Intervention David Dundua et al TCT-1060. A Modified Chimney Technique for the Treatment of Abdominal Aortic Graft Detachment Bernardo Cortese et al TCT-1061. Acute Limb Ischemia Caused by Recurrent Stent Thrombosis in Femoropopliteal Arteries Pil-Ki Min et al TCT-1062. Bilateral Occluded Renal Arteries: An Endovascular Approach Ashraf Manzil et al TCT-1063. A Case of May-Thurner Syndrome Treated with Intralesional UK Infusion Followed by Stent Implantation Jae-Hwan Lee et al TCT-1064. Renal Artery Stenting in Renal Failure Patients: Without Contrast Media, with Intravascular Ultrasound Masayoshi Kimura et al TCT-1065. Successful Recanalization of Both Common Iliac Arteries with Kissing Stent Techniques to the Patient with AxillaryFemoral and Femoral-Femoral Bypass Surgery Jiwon Jang et al The World’s Premier Interventional Experience TCT2011 TCT-1068. The Ruptured Penetrating Aortic Ulcer in the Ascending Aorta Corrected with Stent Graft Sung-Gyu An et al TCT-1069. Complex [Iatrogenic] Vertebral Artery Stenting Harpreet Gilhotra et al TCT-1070. Percutaneous Recanalization of Occluded Aortic- and Bi-Iliac System Massoud Arbabzadeh et al TCT-1071. Severe Angina from Chronic Subclavian Coronary Steal Syndrome Jeffrey Cavendish et al TCT-1072. Flip-it and Stick-it: A Creative Approach to Peripheral Angioplasty Mitul Patel et al TCT-1073. Complex Endovascular Repair of Chronic Type B Dissection Turki Albacker et al TCT-1074. A Case of Transcollateral Retrograde Approach for Totally Obstructed Peroneal Artery Jong-Pil Park et al TCT-1075. Endovascular Repair of a Chronic Aortic and Biiliac Occlusion Immad Sadiq et al TCT-1076. Successful Retrograde Approach of Superficial Femoral Artery Chronic Total Occlusion Without a Stump Shu-kai Hsueh et al TCT-1077. How Do We Handle Mud Pie? Endovascular Recanalization in a Patient with Carotid Occlusion and Repeated TIA Jen-Kuang Lee et al TCT-1078. Carotid Angioplasty While Using an Anchoring Technique of the External Carotid Artery Ramesh Gadepalli et al TCT-1079. A Novel Compression Method for Retrograde Tibial Artery Puncture Toshio Makita et al TCT-1082. Non-surgical Removal of an Entrapped Rotablation Burr by Extracting Drive Shaft Sheath Followed by Balloon Dilatation Kenichi Sakakura et al TCT-1083. Widowmaker Saved by Mobile ECMO Team in PCI Center Without Cardiac Surgery Backup Ulf Jensen et al TCT-1084. Nightmare in the Cath Lab? Bashir Hanif et al TCT-1085. A Second Chance Gopi Manthripragada et al TCT-1086. Acute Cardiogenic Pulmonary Edema Due to Microvascular Spasm Hyun-Woong Park et al TCT-1087. Substrate for Complications Ajay Mhatre et al TCT-1099. Sixteen-Year-Old Male with TAPVC and Recurrent PV Stenosis Daniel Mauriello et al TCT-1100. Transjugular Approach as an Alternative Access for Balloon Mitral Commissurotomy in a Patient with Venous Anomaly Praveen Sreekumar et al TCT-1101. Coiling of a Hemodynamically Significant Coronary Fistula to the Bronchial/Pulmonary Artery Keshav Nayak et al TCT-1102. Placement of a Second Gore Helex Device to Treat Residual Shunting in an Elite Navy Seal Diver Keshav Nayak et al TCT-1103. What and Where Is the Problem? Li-wah Tam et al TCT-1104. Recanalization of Right-Sided Y-Prosthesis Occlusion Thomas Konorza et al TCT-1088. Retrieval of a Perforated Shaldon Catheter Bjoern Plicht et al TAVR TCT-1089. A Healthy Heart Needs More than a Single LIMA Florim Cuculi et al TCT-1105. Subacute Dislocation of a CoreValve Prosthesis Dan Ioanes et al TCT-1090. Stent Avulsion Rajeev Menon et al TCT-1106. PCI After TAVR: Technical Challenges and Solutions Didier Carrié et al Structural Interventions TCT-1091. Transcatheter Closure of Atrial Septal Aneurysm (ASA) of the Fossa Ovalis with Multiple Perforations Do-Hoi Kim et al TCT-1092. Percutaneous Closure of Paravalvular Leaks of a Mechanical Mitral Valve with an Unusual Atrial Position Joachim Schofer et al TCT-1093. Para-Bioprosthetic Mitral Valvular Left Ventricular Pseudoaneurysm Jonathan Roberts et al TCT-1094. Transcatheter Therapy of Lutembacher Syndrome: Easier Said Than Done Shiv Bagga et al TCT-1095. A Rare Case of Left Main Thrombotic Occlusion Following Balloon Aortic Valvuloplasty: Did Protamine Play a Role? Gill Buchanan et al TCT-1080. Use of a Drug-Eluting Stent with Provisional T-stenting Technique in the Treatment of Renal Artery Bifurcation Stenosis Sang-Ho Park et al TCT-1096. Cyanotic Heart Disease Bharat Chanana et al TCT-1081. Vascular Closure Devices Complications Anish George et al TCT-1098. Transcatheter Treatment of Lutembacher Syndrome Garikapati Mahesh et al TCT-1097. Treatment of a 91-Year-Old Patient with Symptomatic Aortic Stenosis Fadi Al-Rashid et al - N o v e m b e r 8 , 2 0 11 TCT-1067. Left Common Iliac Artery Pseudo-Aneurysm Caused by a Gunshot Bullet: A Challenging Transcatheter Treatment Gustavo Carvalho et al Miscellaneous Interventions Tuesday TCT-1066. Percutaneous Revascularization of a Renal Chronic Total Occlusion Salman Arain et al T r a n s c at h e t e r Cardiovascular Therapeutics TCT-1107. Transcatheter Aortic Valve-in-Valve Implantation: Degenerate Surgical Freestyle Aortic Root with False Aneurysm Tiffany Patterson et al TCT-1108. Successful Treatment for Aortic Para Valvular Leak Post Core Valve Carlos Balestrini et al TCT-1109. Combined TEVAR plus Transfemoral TAVI for the Treatment of Thoracic Aortic Disease and Severe Aortic Regurgitation in a Patient with Prior Valve Sparing Root Replacement Philipp Kahlert et al TCT-1110. Successful Transfemoral Aortic CoreValve Implantation During Cardiopulmonary Resuscitation with the LUCAS Device Lionel Leroux et al TCT-1111. Severe Retroperitoneal Bleeding Due to Prostar Dislocation Following Successful Medtronic CoreValve Implantation Vassilis Voudris et al TCT-1112. Retrieval of the Sapien XT Valve from Patient Who Underwent Transcatheter Aortic Valve Implantation Mike Saji et al www.tctconference.com 81 Tuesday, November 8 TCT-1113. A Case of Rotational Atherectomy After Transcatheter Aortic Valve Implantation with the Medtronic CoreValve Prosthesis Mohamed Abdel-Wahab et al TCT-1114. Dual Transcatheter Valvular Intervention for Concomitant Severe Aortic Stenosis and Mitral Regurgitation Pak-Hei Chan et al TCT-1115. Left-to-Right Interventricular Shunt as a Late Complication of Transapical Aortic Valve Implantation Didier Carrié et al TCT-1116. Retroperitoneal Hematoma Post-TAVI Caused by Medial Circumflex Artery Rupture Azeem Latib et al TCT-1117. An Unexpected Complication Immediately Following Transapical Aortic-Valve Implantation Danny Dvir et al TCT-1118. Cardiac Resynchronization Therapy to Improve Cardiac Reserve as a Bridge to Transcatheter Aortic Valve Implantation Martin Sluka et al TCT-1119. Implantation of a Sapien XT Aortic Bioprosthesis Using the Novaflex Catheter (Edwards LifeScience, Irvine, California, USA) Through a Subclavian Access Didier Carrie et al TCT-1120. Migration of the Aortic CoreValve Prosthesis Treated with Rescue “Valve-inValve” Implantation Maciej Dabrowski et al 10:38 am - Discussion 10:41 am - TCT-3. Percutaneous Coronary Intervention for Chronic Total Occlusions: Feasibility, Safety, and Clinical Outcomes at One Year: An Analysis of 307 Patients Virginie Brandao Carreira 10:51 am - Discussion 10:54 am - TCT-4. The Impact of the Location of a Chronic Total Occlusion in a Non Infarct Related Artery on Long-term Mortality in ST-Elevation Myocardial Infarction Patients Loes Hoebers Chronic Total Occlusions 11:07 am - TCT-5. Drug-Eluting Stents for the Treatment of Chronic Total Occlusion: A Comparison with Sirolimus, Paclitaxel, Zotarolimus (Endeavor Resolute), BiolimusA9, EPC Capture, and EverolimusEluting Stent: Multicenter Registry in Asia Sunao Nakamura 10:28 am - TCT-12. Feasibility, Safety, and Clinical Results of In-stent Restenosis Treatment with a Novel Drug-Eluting Balloon: A Single-Center Registry Stefano Galli 11:17 am - Discussion 11:20 am - TCT-6. Long-term Clinical Outcomes After Percutaneous Coronary Intervention for Chronic Total Occlusions in Insulin and Non-Insulin Dependent Diabetes Mellitus: Five-Year Outcomes from a 1,791 Patient Multi-National Registry Bimmer E. Claessen 11:30 am - Discussion 11:33 am - TCT-7. MSCT Guided Coregistration for CTO Procedures: A Pilot Feasibility Study Ravit Barkama 82 11:46 am - TCT-8. Increased Radiation Exposure in Percutaneous Coronary Interventions for Chronic Total Occlusions Sunil Kanwal 11:56 am - Discussion 10:15 am - TCT-1. Successful Recanalization of Chronic Total Occlusions Is Associated with Improved Long-Term Survival Daniel Jones 12:09 pm - Discussion 10:28 am - TCT-2. Prognostic Impact of Complete Coronary Revascularization in Patients with Diabetes Mellitus and Chronic Total Occlusions Renato Valenti program · 10:15 am - TCT-11. In-Stent Restenosis Is Not a Benign Clinical Entity, Presenting as Acute Coronary Syndrome in 40% of Cases Jonathan Behar 10:25 am - Discussion 10:15 am-12:30 pm Room 113 Moderators: Alfredo R. Galassi, Jacques J. Koolen Discussants: Emmanouil S. Brilakis, Mauro Carlino, Thierry Corcos, Goran K. Olivecrona 10:25 am - Discussion 10:15 am-12:30 pm Room 130 Moderators: Fernando Alfonso, Joseph P. Carrozza Jr Discussants: Nicolas A.F. Chronos, Aloke V. Finn, Semih Oktay, Pieter R. Stella 11:04 am - Discussion 11:43 am - Discussion Oral Abstract Sessions Drug-Eluting Balloons and In-Stent Restenosis 11:59 am - TCT-9. Management of Procedural Complications Related to Percutaneous Coronary Intervention of Chronic Total Occlusions via the Retrograde Approach. A Toyohashi Experience Masashi Kimura 12:12 pm - TCT-10. Development of a High-Volume, Multiple-Operator Program for Percutaneous Chronic Total Coronary Occlusion Revascularization: Procedural, Clinical, and Cost-Utilization Outcomes Dimitri Karmpaliotis 12:22 pm - Discussion 12:30 pm - Adjourn T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 10:38 am - Discussion 10:41 am - TCT-13. Findings Supporting Drug Resistance in the Treatment of In-Stent Restenosis Within Drug-Eluting Stents Robert A. Byrne 10:51 am - Discussion 10:54 am - TCT-14. A Single Center, Real World Experience of Drug-Eluting Balloon Use in the Treatment of In-Stent Restenosis and Diffuse Coronary Artery Disease Joann Shannon 11:04 am - Discussion 11:07 am - TCT-15. Paclitaxel-Eluting Balloon in Primary Percutaneous Coronary Intervention in Amsterdam (PAPPA): Short Term Outcome of a Pilot Study Rene van der Schaaf 11:17 am - Discussion 11:20 am - TCT-16. Drug Releasing Balloon with a BTHC Excipient: Six-Month Results on 600 Patients of the International DELUX Registry Ralph Töelg 11:30 am - Discussion 11:33 am - TCT-17. Predilatation with DrugEluting Balloon Followed by Bare Metal Stent Implantation vs. Drug-Eluting Stent in the Treatment of Simple De Novo Native Coronary Stenosis Francesco Liistro 11:43 am - Discussion 11:46 am - TCT-18. Six-Month Angiographic and 18-Month Clinical Results of the Multicenter Randomized DEBIUT (DrugEluting Balloon in Bifurcations Trial) Anouar Belkacemi The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics 11:04 am - Discussion 11:33 am - TCT-27. Four-Year Follow-up of the SYNTAX Trial: Optimal Revascularization Strategy in Patients with Three-Vessel Disease Friedrich W. Mohr 11:07 am - TCT-35. Initial Findings from ABSORB EXTEND on the Use of Overlapping Bioresorbable Scaffolds Alexandre Abizaid 11:43 am - Discussion 11:20 am - TCT-36. One-Year Clinical Outcomes and Multivariate Predictors Following XIENCE V�Everolimus-Eluting Coronary Stent System Implantation in Real-World Clinical Settings Srihari S. Naidu 12:09 pm - Discussion 12:12 pm - TCT-20. Pathologic Features of Everolimus vs. Sirolimus- and PaclitaxelEluting Stents in Human Coronary Arteries Fumiyuki Otsuka 12:22 pm - Discussion 11:46 am - TCT-28. Risk Profile and Three-Year Outcomes from the SYNTAX PCI and CABG Registries Stuart Head 12:30 pm - Adjourn 11:56 am - Discussion Drug-Eluting Stents I and Bioabsorbable Scaffolds 11:59 am - TCT-21. Biodegradable PolymerCoated Sirolimus-Eluting Stent Implantation in Acute Myocardial Infarction Yang Shengli 10:15 am-12:30 pm Room 125 Moderators: Steven R. Bailey, Robert J. Whitbourn Discussants: Bernard R. Chevalier, Marc D. Feldman, Jonathan M. Hill, Pedro R. Moreno 10:15 am - TCT-29. Comparison of EverolimusEluting and Paclitaxel-Eluting Stents: First Report of the Five-Year Clinical Outcomes from the SPIRIT III Trial Gregg W. Stone 10:25 am - Discussion 10:28 am - TCT-22. ABSORB Cohort B Trial: 18 Month Clinical and MSCT Results of the ABSORB Bioresorbable Everolimus Eluting Vascular Scaffold Patrick W. Serruys 10:38 am - Discussion 10:41 am - TCT-23. Drug-Eluting Stents with Biodegradable Polymer: Do They Offer Benefit in the Treatment of Very Small Vessels (< 2.5 mm)? Didier Carrie 10:51 am - Discussion 10:54 am - TCT-24. The “Final” Five-Year Follow-up from the ENDEAVOR IV Trial Comparing a Zotarolimus-Eluting Stent with a Paclitaxel-Eluting Stent Martin B. Leon 11:04 am - Discussion 11:07 am - TCT-30. A Large-Scale, Randomized Comparison of Everolimus-Eluting and Paclitaxel-Eluting Stents: Three-Year Clinical Outcomes from the SPIRIT IV Trial Gregg W. Stone 11:17 am - Discussion 11:20 am - TCT-26. Appropriate Use Criteria for Coronary Revascularization: Results of Retrospective Analysis in a Large Health System Michael Wilson 12:09 pm - Discussion 12:12 pm - TCT-25. Bioresorbable Everolimus Eluting Vascular Scaffold in Small Vessels: One Year Results Roberto Diletti 12:22 pm - Discussion 12:30 pm - Adjourn Drug-Eluting Stents II 10:15 am-12:30 pm Room 111 Moderators: Michael J. Cowley, Peter Wenaweser Discussants: Ronald Caputo, Shu-Kin Li, Marco A. Perin, Richard A. Schatz 10:15 am - TCT-31. Final Five-Year Follow-up from the RESOLUTE First-in-Man Trial Ian T. Meredith 10:25 am - Discussion 10:28 am - TCT-32. Intraprocedural Thrombotic Events During Percutaneous Coronary Intervention in Patients with Non-STElevation Acute Coronary Syndromes are Associated with Adverse Outcomes: Analysis From the ACUITY Trial Margaret B. McEntegart 11:17 am - Discussion 11:30 am - Discussion 11:33 am - TCT-37. Are Adverse Events Following Primary PCI for STEMI More Frequent at US Sites than Sites Outside the US (OUS)? Three-Year Analysis from the HORIZONS-AMI Trial Bruce R. Brodie 11:43 am - Discussion 11:46 am - TCT-38. One-Year Outcomes After Implantation of XIENCE PRIME and XIENCE PRIME Long Lesion Stents in Patients with Coronary Artery Disease: Primary Endpoint Results of the SPIRIT PRIME Multicenter Clinical Trial Marco A. Costa 11:56 am - Discussion 11:59 am - TCT-39. Comprehensive Intravascular Ultrasound Assessment of Stent Area and Its Impact on Restenosis and Adverse Cardiac Events in 403 Patients with Unprotected Left Main Disease Soo-Jin Kang 12:09 pm - Discussion 12:12 pm - TCT-40. Strut Thickness and Type of Metal Alloy of Bare Metal Stents and Frequency of In-Stent-Restenosis: Data from the Swedish Angiography and Angioplasty Registry (SCAAR) Jörg Carlsson et al 12:22 pm - Discussion 10:38 am - Discussion 12:30 pm - Adjourn 10:41 am - TCT-33. Culprit Only or Multivessel Percutaneous Coronary Intervention in Patients with ST-Segment Elevation Myocardial Infarction and Multivessel Disease Mikkel Hougaard Left Main and Bifurcation PCI 10:51 am - Discussion 10:54 am - TCT-34. Everolimus-Eluting Stent vs. Sirolimus- and Paclitaxel-Eluting Stents in Real-Life Practice: Pooled Analysis From the XAMI, COMPARE, and APPENDIX-AMI Trials Matthijs Velders - N o v e m b e r 8 , 2 0 11 11:30 am - Discussion 11:59 am - TCT-19. A Temporal Assessment of Drug Distribution Following Local Balloon Delivery of Nanoparticle Sirolimus Saami Yazdani Tuesday 11:56 am - Discussion 10:15 am-12:30 pm Room 121 Moderators: Theodore A. Bass, Davide Capodanno Discussants: David Antoniucci, Nicola Corvaja, Dietmar H. Glogar, Tak W. Kwan 10:15 am - TCT-41. Impact of Final Kissing Balloon on Outcome After Unprotected Left Main Stenting Klaus Tiroch www.tctconference.com 83 Tuesday, November 8 10:25 am - Discussion 12:09 pm - Discussion 11:30 am - Discussion 10:28 am - TCT-42. Impact of Bifurcation Type and Stenting Technique on Outcome After Unprotected Left Main Stenting Klaus Tiroch 12:12 pm - TCT-50. Complex Coronary Bifurcation Lesions Treated with the Novel Polymer-Free Dedicated Bifurcation Paclitaxel-Eluting Stent (Nile Pax): Nine-Month Clinical and Angiographic Results of the Prospective, Multicenter BIPAX Clinical Trial Ricardo A. Costa 11:33 am - TCT-57. High On-Treatment Platelet Reactivity After Prasugrel Loading Dose and Cardiovascular Events After Percutaneous Coronary Interventions in Acute Coronary Syndromes Laurent Bonello 10:38 am - Discussion 10:41 am - TCT-43. Angiographic Outcome and Predictors of Restenosis in Patients with Unprotect Left Main Disease Treated with Everolimus or Paclitaxel-Eluting Stent: Florence Registry Angela Migliorini 12:30 pm - Adjourn 10:51 am - Discussion Interventional Pharmacology 10:54 am - TCT-44. Unprotected Left Main Stenting in the Real World: Five-Year Outcomes of the French Left Main Taxus Registry Darren Mylotte 10:15 am-12:30 pm Room 122 Moderators: David F. Kong, Steven V. Manoukian Discussants: Patricia J. Best, Kurt Huber, Neal S. Kleiman, Tabassome Simon 11:04 am - Discussion 11:07 am - TCT-45. The ESTROFA-LM Registry: Comparison of Taxus and Xience Stents in Left Main Coronary Artery Disease. Preliminary Results at Three-Year Follow-up Jose M. de la Torre Hernandez 11:17 am - Discussion 11:20 am - TCT-46. Long-term Survival in Patients Undergoing Sirolimus-Eluting Stent PCI of the Unprotected Left Main Coronary Artery According to EuroSCORE, Syntax Score, and GRC: The Milan and New-Tokyo Registry Kensuke Takagi 11:30 am - Discussion 11:33 am - TCT-47. Assessment of the Left Main (LM) with Fractional Flow Reserve (FFR): The Influence of Concomitant Proximal Epicardial Coronary Disease David Daniels 11:43 am - Discussion 11:46 am - TCT-49. Four-Year Follow-up of the SYNTAX Trial: Optimal Revascularization Strategy in Patients with Left Main Disease Patrick W. Serruys 11:56 am - Discussion 11:59 am - TCT-48. Very Long-term Clinical Outcomes of Patients with Coronary Bifurcation Lesions Treated with the Biolimus A9 Coated Dedicated Axxess Stent: Results from the Prospective, Multicenter AXXESS Plus Trial (Final Report of the Study) Eberhard Grube 84 12:22 pm - Discussion program · 10:15 am - TCT-51. Concomitant Clopidogrel and Statin Use and Risk of Major Adverse Cardiovascular Events Following Coronary Stent Implantation Michael Maeng 10:25 am - Discussion 10:28 am - TCT-52. Short-Acting, Reversible Antiplatelet Therapy for Urgent Surgery Early After Coronary DES Implantation Nuccia Morici 10:38 am - Discussion 10:41 am - TCT-53. Death and Acute Myocardial Infarction Associated with Stopping Clopidogrel After Saphenous Vein Graft Percutaneous Coronary Intervention Amit Sachdeva 10:51 am - Discussion 10:54 am - TCT-54. The Impact of HighResidual Platelet Reactivity After Clopidogrel Loading on Long-Term Clinical Outcome of Patients with Acute Coronary Syndromes Receiving an Invasive Treatment: The RECLOSE 2-ACS Trial Renato Valenti 11:43 am - Discussion 11:46 am - TCT-58. Use of Prasugrel in Primary Percutaneous Intervention in Daily Clinical Practice. Results of the Prospective ATACS Registry Uwe Zeymer 11:56 am - Discussion 11:59 am - TCT-59. Concomitant Use of Clopidogrel and Proton Pump Inhibitors and Major Adverse Cardiovascular Events Following Coronary Stent Implantation Michael Maeng 12:09 pm - Discussion 12:12 pm - TCT-60. Protective Effects of Ranolazine Before Elective Percutaneous Coronary Intervention: A Randomized, Double-Blind, Placebo-Controlled Pilot Study Francesco Pelliccia 12:22 pm - Discussion 12:30 pm - Adjourn STEMI Intervention 10:15 am-12:30 pm Room 123 Moderators: Cindy L. Grines, Holger Thiele Discussants: Michael J. Lim, Keith G. Oldroyd, Matthew T. Roe, Gary L. Schaer 10:15 am - TCT-61. Long-term Follow-up of Four Treatment Strategies in Multivessel Disease Following Primary Percutaneous Intervention for Acute Myocardial Infarction Pranobe V. Oemrawsingh 10:25 am - Discussion 11:07 am - TCT-55. Is Clopidogrel Enough for STEMI Patients with Cardiogenic Shock? Klaus Tiroch 10:28 am - TCT-62. Culprit-Lesion-Only vs. Multivessel Revascularization Using Drug-Eluting Stents in ST-Segment Elevation Myocardial Infarction: A KAMIR-Based Analysis Sangwook Kang 11:17 am - Discussion 10:38 am - Discussion 11:20 am - TCT-56. Impact of Major Bleeding on Long-term Mortality in Patients With and Without Anemia Undergoing Percutaneous Coronary Intervention with Bivalirudin Shyam Poludasu 10:41 am - TCT-63. Treatment of Multivessel Coronary Artery Disease in Primary PCI for STEMI: Culprit Only Revascularisation Is Associated with Higher MACE Rates Oliver Guttmann 11:04 am - Discussion T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 11:04 am - Discussion Predictors and Prevention of Stent Thrombosis 10:15 am-12:15 pm Room 124 Moderators: Joost Daemen, Marco Valgimigli Discussants: Anthony A. Bavry, Giuseppe De Luca, Jurrien M. Ten Berg, Bonnie H. Weiner 11:07 am - TCT-65. Does Cytoprotector Mexicor Used Intracoronary During Rescue PCI Limit Reperfusion Myocardial Injury in STEMI Patients? Anton Koledinsky 10:15 am - TCT-71. Incidence and Predictors of Early or Late and Very Late Stent Thrombosis Following Primary PCI with BMS and DES for STEMI: A 16 Year Single-Center Experience Bruce R. Brodie 11:17 am - Discussion 10:25 am - Discussion 11:20 am - TCT-66. Postprocedural ST-Segment Deviation Is an Independent Predictor of Long-term Mortality in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Wichert Kuijt 10:28 am - TCT-72. Stent Thrombosis up to Nine Years Follow-up in Real-World Patients Undergoing Drug-Eluting Stent Implantation Ricardo A. Costa 11:30 am - Discussion 11:33 am - TCT-67. Incremental Value of Thrombus Age to Multiple Biomarkers for the Prediction of One-Year Mortality After ST-Segment Elevation Myocardial Infarction Maik Grundeken 11:43 am - Discussion 11:46 am - TCT-68. Increased Mortality with Post-infarct Ventricular Septal Ruptures at a Tertiary Care Center Lawrence Lazar 11:56 am - Discussion 11:59 am - TCT-69. Factors Associated with Delays in Primary PCI and Cardiac Catheterization Laboratory Activation for ST-Segment Elevation Myocardial Infarctions: A Report from the Activate-SF Registry James McCabe 12:09 pm - Discussion 12:12 pm - TCT-70. Association Between Intraprocedural Thrombotic Events and Adverse Outcomes Following Percutaneous Coronary Intervention for STEMI: The HORIZONS-AMI Trial Ajay J. Kirtane 12:22 pm - Discussion 12:30 pm - Adjourn 10:38 am - Discussion 10:41 am - TCT-73. Impact of Positive Peristent Vascular Remodeling After Sirolimus-Eluting and Paclitaxel-Eluting Stent Implantation on Five-Year Clinical Outcomes: Intravascular Ultrasound Analysis from POET, a Multicenter, Randomized Trial Ki-Woon Kang 10:51 am - Discussion 10:54 am - TCT-74. ST-Elevation Myocardial Infarction (STEMI) Due to Stent Thrombosis: An Enlarging Subgroup of High Risk Patients Bruce R. Brodie 11:04 am - Discussion 11:07 am - TCT-75. Pooled Analysis of RESOLUTE Clinical Trial Long-term Safety Data Martin B. Leon 11:17 am - Discussion 11:20 am - TCT-76. The Clopidogrel Resistance in Stent Thrombosis (CREST) Registry: The Case for Personalized Antiplatelet Therapy? Nalyaka Sambu 11:30 am - Discussion 11:33 am - TCT-77. Stent Thrombosis After Implantation of XIENCE V Everolimus-Eluting Coronary Stent Systems in On-Label and Off-Label Populations: Pooled Two-Year Results from Seven XIENCE V Coronary Stent Trials James B. Hermiller Jr 11:43 am - Discussion 11:46 am - TCT-78. Stent Thrombosis and Dual Antiplatelet Interruption: Insights from the XIENCE V Everolimus-Eluting Coronary Stent System Trials Gregg W. Stone 11:56 am - Discussion 11:59 am - TCT-79. Clinical Outcomes After Acute, Subacute, Late, and Very Late Stent Thrombosis After Primary PCI for STEMI: An Analysis from HORIZONS-AMI Bimmer E. Claessen 12:09 pm - Discussion 12:15 pm - Adjourn Intersection of Diabetes and PCI 10:15 am-12:30 pm Room 110 Moderators: Norman E. Lepor, Robert L. Wilensky Discussants: Kevin J. Beatt, Efrain Gaxiola, Vankeepuran S. Srinivas, Thomas D. Stuckey - N o v e m b e r 8 , 2 0 11 10:54 am - TCT-64. Prasugrel vs. Double Clopidogrel to Overcome High Platelet Reactivity Early Following a 600mg Clopidogrel Loading Dose in Patients Undergoing Primary Percutaneous Coronary Intervention Dimitrios Alexopoulos Tuesday 10:51 am - Discussion T r a n s c at h e t e r Cardiovascular Therapeutics 10:15 am - TCT-80. The Effect of Drug-Eluting Stents on Clinical and Angiographic Outcomes in Diabetic Patients, 3 Years Result: Multicenter Registry in Asia Sunao Nakamura 10:25 am - Discussion 10:28 am - TCT-81. One-Year Outcomes in Over 1,500 Patients with Diabetes Treated with the Resolute Zotarolimus-Eluting Stent Sigmund Silber 10:38 am - Discussion 10:41 am - TCT-82. Impact of Diabetes on Clinical Outcomes after Revascularization with Everolimus- and SirolimusEluting Stents: A Substudy of the SORT OUT IV Trial Anders Junker 10:51 am - Discussion 10:54 am - TCT-83. Impact of the Development and Treatment of Critical Limb Ischemia on Long-term Cardiac Mortality in Diabetic Patients Treated with Percutaneous Coronary Intervention Francesco Liistro 11:04 am - Discussion 11:07 am - TCT-84. Glycosylated Hemoglobin and Outcomes in Diabetic Patients with Acute Myocardial Infarction After Successful Revascularization Anand Singla 11:17 am - Discussion 11:20 am - TCT-85. Three-Year Cardiovascular Event Rates Were Lower in Type 2 Diabetic Patients with Pioglitazone Treatment After Zotarolimus-Eluting Stent Implantation Soon Jun Hong www.tctconference.com 85 Tuesday, November 8 11:30 am - Discussion 10:51 am - Discussion 10:25 am - Discussion 11:33 am - TCT-86. Similar Target Lesion Revascularization In Non-Insulin-Dependent Diabetic Compared with Nondiabetic Patients After Bare Metal Stenting in Lesions Carrying a Low Risk of Restenosis Pier Woudstra 10:54 am - TCT-94. Results of the ALSTER Hypertension Registry: First Experience with Renal Denervation Martin W. Bergmann 10:28 am - TCT-101. Positive Remodeling Is Associated with Vulnerable Coronary Plaque Components Regardless of Clinical Presentation: Virtual Histology-Intravascular Ultrasound Analysis Young Joon Hong 11:43 am - Discussion 11:46 am - TCT-87. Urine NGAL and IL-18 Identify CI-AKI Early in Patients with DM and CKD Undergoing Coronary Angiography/PCI Ayesha Qureshi 11:07 am - TCT-95. Acute and Long-term Follow-up Results of Renal Angioplasty in Takayasu Arteritis Amar Patnaik 11:17 am - Discussion 11:59 am - TCT-88. Twice Daily Dosing of Aspirin Is Biologically More Effective in Patients with Type 2 Diabetes Mellitus and Coronary Artery Disease Jean-Guillaume Dillinger 11:20 am - TCT-96. Impact of Preexisting Cerebral Ischemia Detected by Magnetic Resonance Imaging and Angiography on Clinical Outcomes After Coronary Artery Bypass Graft in Patients Without History of Stroke Won-Jang Kim 12:09 pm - Discussion 11:30 am - Discussion 12:12 pm - TCT-89. Impact of Hyperglycemia in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention: The HORIZONS-AMI Trial David Planer 11:33 am - TCT-97. From US Pivotal Study to 1,200 Patients on Six Continents: A Global Perspective on the Endurant Stent Graft Brij Maini 11:56 am - Discussion 12:22 pm - Discussion 12:30 pm - Adjourn Endovascular Intervention 10:15 am-12:15 pm Room 112 Moderators: Mark W. Burket, Christopher J. Cooper Discussants: Alex Abou-Chebl, Gerald D. Dorros, David B. Jessup, Takao Ohki 10:15 am - TCT-90. The Impact of BTK Runoff Score on the Patency After Stenting for SFA Lesion Ikki Komatsu 10:25 am - Discussion 10:28 am - TCT-91. Six-Year Outcomes Following Endovascular Therapy with Nitinol Stenting for TransAtlantic Inter-Society Consensus C-D Lesions in the Femoropopliteal Segment Tomoharu Dohi 10:38 am - Discussion 10:41 am - TCT-93. COMPLIANCE 360: A Prospective, Randomized, Multicenter Trial Comparing Balloon Angioplasty to Diamondback 360�Orbital Atherectomy System in Calcified Femoropopliteal Disease Raymond Dattilo 86 11:04 am - Discussion program · 11:43 am - Discussion 11:46 am - TCT-98. Carotid Artery Revascularization with Distal Protection in High Surgical Risk Patients in Routine Clinical Practice: Results of the CABANA Safety Surveillance Program L. Nelson Hopkins 11:56 pm - Discussion 11:59 pm - TCT-99. The SAPPHIRE Worldwide Carotid Artery Stenting with Embolic Protection Study: Outcomes to One-Year with Over 7,600 Patients D. Christopher Metzger 12:09 pm - Discussion 12:15 pm - Adjourn Intravascular Imaging: Novel Insights 10:15 am-12:30 pm Room 120 Moderators: Michael Haude, Amir Lerman Discussants: Hector M. Garcia-Garcia, Angela Hoye, Habib Samady, Szilard Voros 10:15 am - TCT-100. Neoatherosclerosis and Late Stent Thrombosis After Coronary Bare Metal Stent Implantation: An Optical Coherence Tomography Study Yuetsu Kikuta T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 10:38 am - Discussion 10:41 am - TCT-102. Multiple Plaque Rupture, Erosion, and Stability as Assessed by Optical Coherence Tomography (OCT), Angioscopy, Intravascular Ultrasound (IVUS), and Coronary Computed Tomographic Angiography (CT Angiography) Yukio Ozaki 10:51 am - Discussion 10:54 am - TCT-103. Head-to-Head Comparison of the Neointimal Response Between Metallic and Bioresorbable EverolimusEluting Scaffolds Using Optical Coherence Tomography Josep Gomez-Lara 11:04 am - Discussion 11:07 am - TCT-104. The Impact of Intravascular Ultrasound Guidance in Routine Percutaneous Coronary Intervention for Conventional Lesions: Data from the EXCELLENT Trial Si-Hyuck Kang 11:17 am - Discussion 11:20 am - TCT-105. Impact of Tissue Prolapse on Short- and Long-term Clinical Outcomes after Stent Implantation in Patients with Acute Myocardial Infarction: An Intravascular Ultrasound Analysis Young Joon Hong 11:30 am - Discussion 11:33 am - TCT-106. Fate of Sidebranches at 6, 12, and 24 Months After Implantation of Bioresorbable Scaffolds: Assessment with 3-Dimensional Optical Coherence Tomography Yoshinobu Onuma 11:43 am - Discussion 11:46 am - TCT-107. Prevalence, Distribution, Predictors, and Outcomes of Patients with Calcified Nodules in Native Coronary Arteries: A Three-Vessel Intravascular Ultrasound Analysis from PROSPECT Yingjia Xu 11:56 am - Discussion 11:59 am - TCT-108. Intraoperative Shuntography for Immediate Control and Improvement of Results of Coronary Bypass Surgery Bagrat Alekyan The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics 11:04 am - Discussion 11:46 am - TCT-117. Off-Pump, Transapical Placement of Artificial Chordae Tendinae to Correct Mitral Insufficiency: European Trial Update Richard C. Daly 11:07 am - TCT-124. Transfemoral Treatment of Bioprosthetic Aortic Valve Failure: Suitability of the Medtronic CoreValve ReValving System Felix Woitek 12:22 pm - Discussion 11:56 am - Discussion 11:17 am - Discussion 12:30 pm - Adjourn 11:59 am - TCT-118. Impact of Severe Left Ventricular Systolic Dysfunction on Clinical and Echocardiographic Outcomes Following Transcatheter Aortic Valve Implantation for Severe Aortic Stenosis Claudia Fiorina 11:20 am - TCT-125. Transcatheter Aortic Valve Implantation for the Treatment of Degenerative Bioprosthetic Surgical Valves: Results from the Global VIV (Valve-in-Valve) Registry Danny Dvir 12:09 pm - Discussion 11:30 am - Discussion 12:12 pm - TCT-119. Long-term Follow-up After Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy in Young Adults Amir-Ali Fassa 11:33 am - TCT-126. Transcatheter Valve-inValve Implantation for Failed Balloon Expandable Transcatheter Aortic Valves Stefan Toggweiler 12:22 pm - Discussion 11:43 am - Discussion 12:30 pm - Adjourn 11:46 am - TCT-127. Low Preprocedural Transaortic Gradient Predicts Adverse Clinical Outcome After Transcatheter Aortic Valve Implantation Nicolas Amabile Structural Heart Disease Intervention 10:15 am-12:30 pm Room 114 Moderators: Zahid Amin, Bernhard Meier Discussants: Sheldon Goldberg, Igor F. Palacios, Matthew J. Price 10:15 am - TCT-110. Follow-up of Patients with Ostium Secundum Atrial Septal Defect with Severe Pulmonary Arterial Hypertension Undergoing Device Closure Sudhir C. Sinha 10:25 am - Discussion 10:28 am - TCT-111. Migraine Visual Aura With or Without Headache: Association with Right to Left Shunt and Assessment Following Transcutaneous Closure M. Khalid Mojadidi 10:38 am - Discussion 10:41 am - TCT-112. Interim Data from AMPLATZER�Cardiac Plug Registry Jai-Wun Park 10:51 am - Discussion 10:54 am - TCT-113. Safety and Efficacy of Balloon Atrial Septostomy for Advanced Pulmonary Hypertension in Patients Failing Prostanoid Therapy Brooks Kuhn 11:04 am - Discussion 11:07 am - TCT-114. Standalone Balloon Aortic Valvuloplasty: Indications and Outcomes from the UK in the Transcatheter Valve Era David Hildick-Smith 11:17 am - Discussion 11:20 am - TCT-115. Immediate and Long-term Results of Mitral Balloon Valvuloplasty in Patients with Severe Pulmonary Hypertension Rodrigo Blanco 11:30 am - Discussion 11:33 am - TCT-116. Long-term Follow-up After Myocardial Contrast EchocardiographyGuided Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy Amir-Ali Fassa Transcatheter Aortic Valve Replacement I 10:15 am-12:15 pm Room 131 Moderators: Josep Rodes-Cabau, John G. Webb Discussants: Larry S. Dean, Michael Kang-Yin Lee, Gilles Rioufol, Thomas Walther 10:15 am - TCT-120. Midterm Outcomes Following Transcatheter Aortic Valve Replacement with Both Edwards SAPIEN and Medtronic CoreValve ReValving System�Devices According to VARC Definitions: The Milan Experience Gill L. Buchanan 10:25 am - Discussion 10:28 am - TCT-121. Late Structural Integrity of Balloon Expandable Stents Used for Transcatheter Aortic Valve Replacement: Assessment by Multidetector Computerized Tomography Alex Willson 10:38 am - Discussion 10:41 am - TCT-122. Short- and Long-term Safety and Effectiveness of Transcatheter Aortic Valve Implantation in a Failing Surgical Aortic Bioprosthesis Ralf Mueller 10:51 am - Discussion 10:54 am - TCT-123. Transcatheter Aortic Valve Replacement with Edwards Sapien Valve for Treatment of Degenerated Bioprosthesis: UK Sapien User Group Experience Vinnie Bapat - N o v e m b e r 8 , 2 0 11 11:43 am - Discussion 12:12 pm - TCT-109. Arterial Response to Sirolimus-Eluting Stents with Bioabsorbable Polymer: First IVUS Report from the DESSOLVE-I FIM Trial Kenji Sakamoto Tuesday 12:09 pm - Discussion 11:56 am - Discussion 11:59 am - TCT-128. Transaortic Transcatheter Aortic Valve Implantation Using the Sapiens Valve for Patients with No Optional Artery Access: A New Promising Approach Kentaro Hayashida 12:09 pm - Discussion 12:15 pm - Adjourn Transcatheter Aortic Valve Replacement II 10:15 am-12:30 pm Room 132 Moderators: Georg Lutter, E. Murat Tuzcu Discussants: Jorge A. Belardi, Reginald I. Low, Terje K. Steigen 10:15 am - TCT-129. Outcome of Conservative Management in Patients with Aortic Valve Stenosis Ineligible for Transcatheter Treatment Massimo Napodano 10:25 am - Discussion 10:28 am - TCT-130. TAVR for High-Risk Patients with Severe Aortic Stenosis Who Satisfy All the Criteria for Conventional Aortic Valve Replacement: A United Kingdom-Based Cost-Utility Analysis John Eaton www.tctconference.com 87 Tuesday, November 8 10:38 am - Discussion 10:41 am - TCT-131. Transfemoral Transcatheter Aortic Valve Implantation vs. Surgical Aortic Valve Replacement in Patients with Severe Aortic Stenosis Marco Barbanti 10:51 am - Discussion 10:54 am - TCT-132. Intracardiac Echocardiography: A New Guiding Tool for Transcatheter Aortic Valve Replacement Thomas Bartel 11:04 am - Discussion 11:07 am - TCT-133. Management of Paravalvular Leaks During and After Transcatheter Valve Replacement Claudia A. Martinez Bermudez 11:17 am - Discussion 11:20 am - TCT-134. Immediate Results and Mid-term Follow-Up of Transcatheter Closure of Paravalvular Leaks with Amplatzer Vascular Plug III Device Manuel Paulo 11:30 am - Discussion 11:33 am - TCT-135. Transcatheter Aortic Valve Replacement with Edwards Sapien Valve via Transaortic Route: European Multicenter Experience Vinnie Bapat Exhibit Hall Opens 12:00 pm Lunch will be provided. Scientific Symposia (Continued) Device-Based Approaches for Heart Failure: Recent Developments and New Directions This session is not CE/CME accredited. 1:00 pm-6:20 Room 123 pm Session I. Indwelling Pressure Monitoring for Patients with Advanced Heart Failure Moderators: Daniel Burkhoff, Ileana L. Piña Discussants: Maria Rosa Costanzo, Neal L. Eigler, JoAnn Lindenfeld 1:00 pm - Featured Lecture: Pressure Monitoring for Patients with Advanced Heart Failure: Past, Present, and Future Maria Rosa Costanzo 1:15 pm - CardioMems: Device and Studies JoAnn Lindenfeld 3:21 pm - New Therapies for Pulmonary Arterial Hypertension Irene M. Lang 3:33 pm - Discussion with Audience Q&A Session III. Left Ventricular Assist Devices Moderators: Joseph C. Cleveland, Maria Rosa Costanzo Discussants: Renzo Cecere, Robert D. Dowling, Robert D.B. Jaquiss, Francis D. Pagani, Joseph G. Rogers, Matt Romano, Marvin J. Slepian 3:48 pm - Featured Lecture: LVADs: State of the Art Francis D. Pagani 4:03 pm - Temporary Left Ventricular Support During High-Risk PCI: New Insights from PROTECT II Jeffrey J. Popma 4:15 pm - SynCardia Marvin J. Slepian 4:27 pm - The REVIVE-IT Study Matt Romano 4:39 pm - HeartMate II for “Less Sick” Patients Joseph G. Rogers 11:43 am - Discussion 1:27 pm - Savacor: Device and Studies Neal L. Eigler 11:46 am - TCT-136. Twelve-Month Results from the CoreValve Transcatheter Aortic Valve Australia-New Zealand Study Ian T. Meredith 4:51 pm - CircuLite: Update on the EU Clinical Study of “Less Sick” Patients Robert D. Dowling 1:39 pm - Chronic Pressure Monitoring in Heart Failure: Regulatory Perspectives Ileana L. Piña 5:03 pm - Sunshine Heart Renzo Cecere 11:56 am - Discussion 11:59 am - TCT-137. Comparison of Balloonexpandable and Self-expandable Bioprosthesis for Transcatheter Aortic Valve Implantation Massimo Napodano 12:09 pm - Discussion 12:12 pm - TCT-138. Aortic Annulus Diameter Determination by Multidetector Computed Tomography: Reproducibility, Applicability, and Implications for Transcatheter Aortic Valve Replacement Ronen Gurvitch 12:22 pm - Discussion 12:30 pm - Adjourn 1:51 pm - Discussion with Audience Q&A: Pressure Sensors and Other Technologies for Keeping Patients Out of Hospital Session II. Update on Novel Therapies for Heart Failure Moderators: JoAnn Lindenfeld, Joseph G. Rogers Discussants: David S. Feldman, Paul J. Hauptman, Irene M. Lang, Serjan D. Nikolic, Paul A. Sobotka 2:06 pm - Featured Lecture: Novel Devices for Refractory Heart Failure William T. Abraham 2:21 pm - Role of Percutaneous Mitral Repair in Patients with CHF Olaf Franzen 2:33 pm - Renal Nerve Ablation (Ardian): Potential for Heart Failure Paul A. Sobotka 2:45 pm - CardioKinetics: Device and Studies Serjan D. Nikolic 2:57 pm - BioControl: Device and Studies Paul J. Hauptman 88 3:09 pm - IMPULSE Dynamics: Device and Studies David S. Feldman program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 5:15 pm - The CircuLite Percutaenous Long-term VAD Daniel Burkhoff 5:27 pm - The HeartWare MVAD Andreas Brieke 5:39 pm - Right Ventricular Support: The Need and the Devices Joseph C. Cleveland 5:51 pm - The Berlin Heart Pediatrics VAD Robert D.B. Jaquiss 6:03 pm - Discussion with Audience Q&A 6:20 pm - Adjourn The World’s Premier Interventional Experience TCT2011 1:00 pm-6:10 Room 131 pm 1:00 pm - The FDA CREST Analysis: Data Which Further Defines the Roles of CEA and CAS Peter A. Schneider 1:12 pm - Explaining the Differences Between European and US CAS Trial Results William A. Gray 1:24 pm - The Case for a Trial of Medical Therapy vs. Revascularization in Asymptomatic Patients Thomas G. Brott 4:23 pm - The Surgical Approaches to and Indications for Iliofemoral Venous Obstruction Anthony J. Comerota 3:08 pm - The Role of the Interventional Cardiologist in Treating Acute Stroke Stephen R. Ramee 4:33 pm - Endovascular Management of SVC Syndrome Hugo F. Londero 3:16 pm - Discussion with Audience Q&A 4:43 pm - Results of a Multicenter Registry of Rheolytic Thrombectomy for DVT Robert A. Lookstein Session VIII. Flash Debates: Round Two Moderators: Gary M. Ansel, Bernhard Reimers Discussants: Thomas G. Brott, Anthony J. Comerota, William A. Gray, Sumaira Macdonald, Issam D. Moussa, Peter A. Schneider Flash Debate VI 3:31 pm - Proximal Protection Should Be Used Whenever Anatomy and Physiology Allow! Sumaira Macdonald 3:36 pm - The Method of Protection Has No Meaningful Impact on CAS Outcomes! Issam D. Moussa 3:41 pm - Discussion and Vote Flash Debate VII 1:32 pm - Risk-Adjusted National Benchmarks for the Performance of CAS Jon S. Matsumura 3:45 pm - The Misinterpretation of CREST and ICSS: CAS Remains Unproven for Standard Surgical Risk Patients! Anthony J. Comerota 1:40 pm - Procedure Rehearsal in CAS Can Improve Procedural Performance and Reduce the Learning Curve Isabelle Van Herzeele 3:50 pm - CEA Is No Longer Justifiable in the Standard Risk Patient Given Results of CREST! William A. Gray 1:48 pm - Managing the Asymptomatic Octogenarian: Who Gets Revascularization, and How to Reduce Adverse Outcomes? Gary M. Ansel 3:55 pm - Discussion and Vote 1:58 pm - Complications During CAS: Recognition and Management D. Christopher Metzger 2:10 pm - Managing Carotid Access from Straight-Forward to Complex Bernhard Reimers 2:20 pm - Is the Carotid String-Sign Off-limits for Carotid Intervention? Colin M. Barker 2:30 pm - Characterization of Plaque Prolapse Following Carotid Artery Stenting by OCT Bernhard Reimers 2:38 pm - A New Variable (High-Low) Flow Reversal Catheter for Transcervical Carotid Intervention Enrique Criado 2:46 pm - Diffusion Weighted MRI Evaluation of the Effectiveness of Proximal Protection (MOMA) During Carotid Stenting: The DESERVE Prospective Study Alberto Cremonesi Flash Debate VIII 3:59 pm - Asymptomatic Patients with Carotid Stenosis Should Be Treated with Best Medical Therapy Given Improvements in Outcomes! Thomas G. Brott 4:04 pm - The Only Randomized Data That Exists for the Asymptomatic Patient Dictates Revascularization! Peter A. Schneider 4:09 pm - Discussion and Vote Session IX. Venous Therapies Moderators: Anthony J. Comerota, Raghu Kolluri Discussants: Michael D. Dake, Michael R. Jaff, Paul H. Kramer, Hugo F. Londero, Robert A. Lookstein, Lindsay S. Machan, Raghotham R. Patlola, Robert M. Schainfeld, Mohsen Sharifi 4:13 pm - Venous Anatomy and Duplex Interpretation for the Interventionalist Raghotham R. Patlola 4:53 pm - EVISTA-DVT Trial Results of Endovenous Infrainguinal Stenting for DVT Mohsen Sharifi 5:03 pm - Should Intervention for Iliofemoral DVT Be Considered Standard of Care? Review of the Data Michael R. Jaff - N o v e m b e r 8 , 2 0 11 Session VII. Cerebrovascular Intervention Moderators: Alex Abou-Chebl, Philip M. Meyers Discussants: Gary M. Ansel, Colin M. Barker, Thomas G. Brott, Alberto Cremonesi, Enrique Criado, William A. Gray, L. Nelson Hopkins, Jon S. Matsumura, D. Christopher Metzger, Stephen R. Ramee, Bernhard Reimers, Peter A. Schneider, Isabelle Van Herzeele 2:56 pm - Current Interventional Approach to Acute Stroke (and SAMMPRIS in Perspective) L. Nelson Hopkins Tuesday Endovascular Intervention (Part 2) T r a n s c at h e t e r Cardiovascular Therapeutics 5:13 pm - IVC Filters 101: Indications for Use, Removal, and Techniques Robert M. Schainfeld 5:23 pm - The Spectrum of Ablation Options for Office-Based Saphenous Vein Practice Lindsay S. Machan 5:33 pm - The Elements Required to Begin a Successful Practice in Venous Insufficiency Paul H. Kramer 5:43 pm - Challenges to the Concept of Chronic Cerebrospinal Venous Insufficiency (CCSVI): What Is the Way Forward? Roger M. Greenhalgh 5:53 pm - Discussion with Audience Q&A 6:10 pm - Adjourn Hot Topics in Interventional Cardiology: ACC.11 Highlights for the Interventional, Invasive, and General Cardiologist 1:00 pm-6:00 Room 132 pm Session I. Surgical vs. Nonsurgical Therapy for CAD Moderators: James B. McClurken, Thomas A. Ports Discussants: Robert O. Bonow, Andrew J. Boyle 1:00 pm - Impact of the STICH Trial on Revascularization for LV Dysfunction Andrew J. Boyle 1:12 pm - CABG vs. PCI for Unprotected Left Main Disease Edward J. McNulty 1:24 pm - Viability Studies: Are They Worth the Cost? Robert O. Bonow 1:36 pm - Discussion www.tctconference.com 89 Tuesday, November 8 Session II. What’s New in Systemic Hypertension? Moderators: Michael H. Crawford, Patrick T. O’Gara Discussant: Anthony E. Steimle 2:00 pm - Evaluation of the Patient with New Hypertension Paul A. Sobotka 2:12 pm - Current Treatment Recommendations for Hypertension Michael H. Crawford 2:24 pm - Hypertension Trials at ACC 2011 Anthony E. Steimle 2:36 pm - Discussion Session III. Stroke Prevention in Interventional Cardiology Moderators: David R. Holmes Jr, E. Murat Tuzcu Discussants: Lee R. Guterman, John G. Webb, Jesse Weinberger 3:00 pm - Definition of Stroke Jesse Weinberger 3:10 pm - Stroke During TAVR, PCI, and Surgery John G. Webb 3:20 pm - Impact of Stroke During Interventional Procedures Lee R. Guterman 3:30 pm - New Devices for Stroke Prevention Eberhard Grube 3:40 pm - Discussion with Audience Q&A Session IV. Stroke Prevention in Atrial Fibrillation Moderators: Ralph G. Brindis, Byron K. Lee Discussants: Michael D. Ezekowitz, Peter J. Goadsby, Karl-Heinz Kuck, Vivek Y. Reddy 4:00 pm - Importance of Stroke Prevention in Patients with Atrial Fibrillation Davendra Mehta 4:10 pm - Left Atrial Appendage Occlusion Vivek Y. Reddy 4:20 pm - What Is the Role of Atrial Fibrillation Ablation in Stroke Prevention? Karl-Heinz Kuck 4:30 pm - Risk of Bleeding vs. Stroke, HAS-BLED and CHADS2, and New Antithrombotic Agents Michael D. Ezekowitz 4:40 pm - Discussion with Audience Q&A Session V. Genetics and Pharmacokinetic Assessment Moderators: George D. Dangas, David J. Moliterno Discussants: Somjot S. Brar, Germano Di Sciascio, Paul A. Gurbel, Dietmar Trenk 5:00 pm - Prognostic Importance of High Platelet Reactivity Somjot S. Brar 5:10 pm - What Might We Expect from the TRIGGER-PCI Late BREAKING TRIAL Presentation? Insights from Public Domain Data Dietmar Trenk 5:20 pm - What Is the Optimal Strategy for Genetic Polymorphism and Platelet Function Testing? Paul A. Gurbel 5:30 pm - Is There a Bleeding Risk with High Platelet Inhibition? Germano Di Sciascio 5:40 pm - Discussion with Audience Q&A 6:00 pm - Adjourn Identifying the High-Risk Patient and Lesion: From Vulnerable Plaque to Ischemia and Viability 1:00 pm-6:00 Room 124 pm Session I. Introductory Lecture 1:00 pm - Conceptual Redesign: Today’s Culprit vs. Future Culprits: Ischemia Today vs. Tomorrow Gregg W. Stone Session II. What Makes a Coronary Plaque Vulnerable? Moderators: Prediman K. Shah, Robert L. Wilensky Discussants: Hector M. Garcia-Garcia, James A. Goldstein, Pedro R. Moreno, Christodoulos I. Stefanadis, Yasunori Ueda, Renu Virmani, Szilard Voros 1:10 pm - What Structural Features Predict Plaque Vulnerability and Future Events? New 2011 Insights Renu Virmani 1:22 pm - What Plaque-Intrinsic Biochemical and Molecular Features Predict Lesion Vulnerability and Future Events? New 2011 Insights Robert L. Wilensky 1:34 pm - Emerging Paradigms in Atherosclerosis: From Inflammation to Cholesterol Metabolism Prediman K. Shah 90 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 1:49 pm - 2011 Intravascular Imaging Insights into Focal Plaque Vulnerability and Identification: From VH-IVUS to OCT to NIRS Gary S. Mintz 2:01 pm - 2011 Intravascular Imaging Insights into Focal Plaque Temporal Stability Akiko Maehara 2:11 pm - Shear Stress 1: Influences of Low vs. High Shear Stress on Plaque Progression Habib Samady 2:21 pm - Shear Stress 2: New Insights from PREDICTION Peter H. Stone 2:31 pm - Social Stress-Related Triggers of Acute Myocardial Infarction and Sudden Death: Examples and Mechanisms Robert A. Kloner 2:41 pm - Is Noninvasive Imaging Useful to Identify Vulnerable Patients for Cardiac Arrest and MI? Jeroen J. Bax 2:51 pm - Can MSCT Truly Identify Vulnerable Plaque? Udo Hoffmann 3:01 pm - How Far Away Is Noninvasive Molecular Imaging of Vulnerable Plaque? Farouc Jaffer 3:11 pm - Does Endothelial Dysfunction Meaningfully Contribute to Plaque Vulnerability or Ischemia? Amir Lerman 3:21 pm - Can We Identify Vulnerable Patients and Vulnerable Plaque? Do We Know Enough to Treat High-Risk Lesions? Discussion with Audience Q&A Session III. Role of Ischemia in Predicting Short-term and Late Events Moderators: John A. Ambrose, Amir Lerman Discussants: Sripal Bangalore, Sorin J. Brener, Allen Jeremias, Morton J. Kern, James K. Min, John A. Spertus, Christodoulos I. Stefanadis, Pim A.L. Tonino 3:37 pm - Relationship Between Ischemic Burden and Prognosis (from Death and MI to Angina and Revascularization) Leslee J. Shaw 3:47 pm - Might Revascularization of Ischemia Reduce Death and MI: From Old RCTs (ACIP, SWISSI II) to New Insights from COURAGE William E. Boden 3:57 pm - A Reevaluation of the Importance of Complete Revascularization Ajay J. Kirtane 4:07 pm - Functional vs. Anatomic Revascularization: What Should Be the Goal? Morton J. Kern The World’s Premier Interventional Experience TCT2011 4:27 pm - Yes, Until Proven Otherwise! Judith S. Hochman 1:20 pm - New European Guidelines for Stroke Prevention in Atrial Fibrillation Peter Sick 1:30 pm - How Do the New Anticoagulants Change the Equation of LAA Closure? Vivek Y. Reddy 4:37 pm - No, Until Proven Otherwise! Julinda Mehilli Debate: Most Patients with Atrial Fibrillation Are Good Candidates for Anticoagulation 4:47 pm - Design, Rationale, and Status of the FAMI II Trial William F. Fearon 1:40 pm - Pro! Michael D. Ezekowitz 4:55 pm - Design, Rationale, and Status of the ISCHEMIA Trial David J. Maron 5:03 pm - Relationship Between Ischemia and Vulnerable Plaque: An Integrated Theory Bernard De Bruyne 5:13 pm - Is Alleviating Ischemia the Key to Improving Cardiovascular Prognosis, and Should This Affect the Practice of PCI Today? Discussion with Audience Q&A Session IV. Is Viability (or Its Assessment) No Longer Essential? Moderators: Daniel S. Berman, Vladimir Dzavik Discussants: Robert O. Bonow, Bernard J. Gersh 5:28 pm - STICH Post-Mortem: Is the Glass Half Empty or Half Full? Robert O. Bonow 5:38 pm - The Totally Negative STICH Viability Substudy: Limitations and Historical Context Bernard J. Gersh 5:48 pm - Should Patients with Severe Coronary Artery Disease, Depressed LVEF, and No or Minimal Inducible Ischemia Undergo Revascularization? Discussion with Audience Q&A 6:00 pm - Adjourn Left Atrial Appendage Closure: Indications, Devices, and Techniques 1:00 pm-6:20 Room 130 pm Session I. Background and Basics Moderators: Peter J. Goadsby, Vivek Y. Reddy Discussants: Paul S. Chan, Michael D. Ezekowitz, Peter Sick 1:00 pm - Stroke Risk in Atrial Fibrillation: Mechanisms and Frequency Peter J. Goadsby 1:45 pm - Con! Paul S. Chan 1:50 pm - Discussion with Audience Q&A Session II. The Evidence: Results of Clinical Trials Moderators: Steven L. Almany, Howard C. Herrmann Discussants: David R. Holmes Jr, Bernhard Meier, Horst Sievert 2:00 pm - Update from PROTECT AF David R. Holmes Jr 2:10 pm - Emerging Data from Continued Access and PREVAIL Status Saibal Kar 2:20 pm - LAA Closure in Patients Who Cannot Take Warfarin: Results of the ASAP Trial Horst Sievert 2:30 pm - Update on the ACP Registries Bernhard Meier 2:40 pm - Discussion with Audience Q&A Session III. Imaging for LAA Closure Moderators: Frank E. Silvestry, Brian Whisenant Discussants: Swaminatha V. Gurudevan, Robert J. Siegel, Nina C. Wunderlich 3:30 pm - LAA Closure with the Watchman: A Step-by-Step Tutorial Zoltan G. Turi 3:40 pm - LAA Closure with the Amplatzer Cardiac Plug: A Step-by-Step Tutorial Jai-Wun Park 3:50 pm - Discussion with Audience Q&A Session V. New LAA Closure Devices and Techniques Moderators: James B. Hermiller Jr, Peter Sick Discussants: A. Marc Gillinov, David W.M. Muller, Steven J. Yakubov 4:00 pm - Initial Experience with the Gen 4 Watchman: Results from the EVOLVE Trial Horst Sievert 4:10 pm - The Coherex WaveCrest: Device Design and Human Results to Date David W.M. Muller 4:20 pm - SentreHEART Device: Description, Technique, and Known Outcomes Steven J. Yakubov 4:30 pm - Other Novel Endocardial and Epicardial Techniques Horst Sievert 4:40 pm - Surgical Ligation and AtriCure: Safety and Acute/Sustained Efficacy A. Marc Gillinov 4:50 pm - Discussion with Audience Q&A Session VI. Difficult Cases and Troubleshooting Moderators: David J. Hildick-Smith, Peter N. Ruygrok Discussants: Maurice Buchbinder, David R. Holmes Jr, Brij Maini, Ramon Quesada, Vivek Y. Reddy, Peter Sick, Zoltan G. Turi, Gian Paolo Ussia, Brian Whisenant, Stephen G. Worthley 5:00 pm - Case Presentation: Device Embolization Stephen G. Worthley 2:50 pm - Pre- and Post-procedural TEE Nina C. Wunderlich 5:07 pm - Device Embolization: Frequency, Prevention, and Management David R. Holmes Jr 3:00 pm - Specific Echocardiographic Imaging Approaches and Angles: A How-to Guide Robert J. Siegel 5:14 pm - Case Presentation: DeviceAssociated Thrombus Ramon Quesada 3:10 pm - Lessons Learned from 3-D TEE Swaminatha V. Gurudevan 5:21 pm - Thrombus on the Device: Origins, Frequency, and Implications for Anticoagulation Brian Whisenant 3:20 pm - Discussion with Audience Q&A Session IV. Latest LAA Closure “Approved” Device Iterations and Device-Specific Implant Considerations Moderators: Peter C. Block, Roger J. Laham Discussants: Jai-Wun Park, Zoltan G. Turi - N o v e m b e r 8 , 2 0 11 The Great Debate: OAT Was Negative: Do the Results Extend to STEMI Between 12 and 48 Hours and CTOs with Ischemia? 1:10 pm - Bleeding from Chronic Anticoagulation: How Large a Problem, and Who Is at Risk? Michael D. Ezekowitz Tuesday 4:17 pm - An Observational Study of Ischemia-Guided vs. Non-Ischemia-Guided Revascularization in 5,340 Patients with Multivessel Disease Young-Hak Kim T r a n s c at h e t e r Cardiovascular Therapeutics 5:28 pm - Case Presentation: Persistent LAA Patency Despite Adequate Device Position Brij Maini 5:35 pm - Residual Flow: What Does It Mean? Vivek Y. Reddy www.tctconference.com 91 Tuesday, November 8 5:42 pm - Case Presentation: Periprocedural Stroke Zoltan G. Turi 1:05 pm - Final Lessons from the NEVO Program Daniel I. Simon 2:56 pm - Progress with a Zotarolimus-Filled Stent: Technology and Preclinical Results Josiah N. Wilcox 5:49 pm - Stroke Early and Late After LAA Occlusion: Thrombotic, Hemorrhagic, Air Embolism, and Others Maurice Buchbinder 1:13 pm - The SYNERGY Stent: Technology, EVOLVE Design, and Future Directions Ian T. Meredith 3:03 pm - Sirolimus Elution from a Nanoparticle-Based Stent (Envision Scientific): Technology and Preclinical Results Heleen van Beusekom 5:56 pm - Case Presentation: Pericardial Tamponade Gian Paolo Ussia 6:03 pm - Effusions and Pericardial Tamponade Peter Sick 6:10 pm - Discussion with Audience Q&A 6:20 pm - Adjourn Next Generation Drug-Eluting Stents and Bioabsorbable Scaffolds 12:15 pm-6:00 Room 104 pm Session I. The Big Picture Moderators: Martin B. Leon, Patrick W. Serruys Discussants: Ian T. Meredith, John A. Ormiston, Manel Sabate, Sigmund Silber Opening Debate: The Promise of Next Generation AntiRestenotic Devices 12:15 pm - Perspective 1: Durable Polymers Can Be a Positive Attribute of a Stent! Elazer R. Edelman 12:23 pm - Perspective 2: Bioabsorbable Polymers, Polymer-Free Systems, and Bioabsorbable Scaffolds Will Improve Late Outcomes and Reduce the Reliance on Dual Antiplatelet Therapy! Stefan Verheye 12:31 pm - Perspective 3: How Can the Current DES Results Get Any Better? And What Kinds of Trials Will This Take? Gregg W. Stone 12:39 pm - Discussion with Audience Q&A Session II. Representative DES with Bioabsorbable Polymers Moderators: Ian T. Meredith, Stefan Verheye Discussants: Alexandre Abizaid, Bernard R. Chevalier, Run-Lin Gao, Daniel I. Simon, Glenn Van Langenhove, Robert J. Whitbourn 12:47 pm - Lessons from BioMatrix and the LEADERS Trial at Four Years: Transitioning into the Global Program Patrick W. Serruys 12:57 pm - Long-term Insights from the Nobori Stent Program Bernard R. Chevalier 92 program · 1:21 pm - Program Update: Micell Crystalline Sirolimus Elution from a Bioabsorbable Polymer John A. Ormiston 1:29 pm - FIREHAWK Bioabsorbable Polymer Sirolimus-Eluting Stent: Update on the First-in-Man, TARGET I, and TARGET II Studies Run-Lin Gao 1:37 pm - Program Update: Voclosporin and Corolimus Elution from a Bioabsorbable Omega-3 Fatty Acid Carrier Glenn Van Langenhove 1:45 pm - Program Update: Excella Novolimus Elution from Bioabsorbable Polymer-Coated Stents Alexandre Abizaid 1:53 pm - Discussion with Audience Q&A Session III. Representative Polymer-Free DES Moderators: Dean J. Kereiakes, Gregg W. Stone Discussants: Alexandre Abizaid, Didier Carrie, Ricardo A. Costa, Run-Lin Gao, Julinda Mehilli, Heleen van Beusekom, Josiah N. Wilcox 3:10 pm - Discussion with Audience Q&A Session IV. Stents Designed to Enhance Healing Moderators: Nicolas A.F. Chronos, Robert S. Schwartz Discussants: Henricus J. Duckers, Michael Haude, Julio C. Palmaz 3:22 pm - Perspectives on the Genous Anti-CD34 Antibody-Coated Stent: From HEALING I/II to TRIAS HR to Use During Primary PCI Henricus J. Duckers 3:32 pm - A Combination Sirolimus-Eluting Anti-CD34 Antibody-Coated Stent: Description and REMEDEE Trial Michael Haude 3:42 pm - Endothelial Cell Guidance: Technological Possibilities Julio C. Palmaz 3:50 pm - Discussion with Audience Q&A 2:05 pm - The Translumina Yukon ISAR-TEST Family of Trials: A Synthesis of the Long-term Trial Results Julinda Mehilli Session V. Bioabsorbable Scaffolds Moderators: Jacques J. Koolen, Ron Waksman Discussants: Alexandre Abizaid, Hector M. Garcia-Garcia, Antoine Lafont, Jens Flensted Lassen, Ian T. Meredith, Patrick W. Serruys, Stefan Verheye, Renu Virmani, Wojciech Wojakowski 2:17 pm - The BioFreedom DES: Late Results, Technology Challenges, and Next Steps Eberhard Grube 4:00 pm - The Promise and Challenges of Bioabsorbable Scaffolds (As I See It)! Renu Virmani 2:25 pm - Two-Year Results from the VESTAsync II Randomized Trial with a Hydroxyapatite Polymer-Free Sirolimus-Eluting Stent Alexandre Abizaid 4:08 pm - Imaging Bioabsorbable Scaffolds: IVUS, VH, OCT, CTA, and More: From Research Insights to Clinical Utility Hector M. Garcia-Garcia 2:33 pm - PAX Polymer-Free Paclitaxel-Eluting Technology and Clinical Trial Update Ricardo A. Costa 2:41 pm - The Cre8 Stent (Sirolimus Elution from Reservoirs in a Carbofilm-Coated Stent): Device Description and Clinical Development Program Didier Carrie 2:49 pm - Experimental and First-in-Man Data with the BICARE Polymer-Free Dual-Drug (Sirolimus and Probucol)-Eluting Stent Run-Lin Gao T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 4:18 pm - Measurement, Magnitude, and Clinical Relevance of Coronary Endothelial Dysfunction After Metallic First and Second Generation DES Wojciech Wojakowski 4:26 pm - Assessment and Potential Clinical Benefits of Restored Late Endothelial Function After Scaffold Bioabsorption Ian T. Meredith 4:34 pm - BVS in Simple Lesions: Five-Year Cohort A and Two-Year Cohort B Results: Integrated Insights Patrick W. Serruys The World’s Premier Interventional Experience TCT2011 5:08 pm - ELIXIR Novolimus and Myolimus Elution from a Fully Bioabsorbable Scaffold Stefan Verheye 5:18 pm - AMS Redesign and Relaunch: Lessons Applied and Current Status Jacques J. Koolen 5:26 pm - REVA Redesign and Relaunch: Lessons Applied and Current Status Alexandre Abizaid 5:34 pm - ART: Progress with a Novel Bioabsorbable PLLA Stent Antoine Lafont 5:42 pm - Discussion with Audience Q&A 6:00 pm - Adjourn The Valvular Heart Disease Summit (Part 2): Mitral Valve Therapies 1:00 pm-6:00 Room 135 pm Session I. Guidelines and Global Developments Moderators: Blase A. Carabello, Allan Schwartz Discussants: David H. Adams, Robert O. Bonow, James S. Gammie, Maurice E. Sarano, Alec Vahanian 1:00 pm - Critical Appraisal of the Latest MR Guidelines 1: Distinguishing Fact from Evidence Level C Opinion Robert O. Bonow 1:10 pm - Critical Appraisal of the Latest MR Guidelines 2: A Future Wish List David H. Adams 1:20 pm - MR Therapy Trends in the United States (DMR and FMR) 1: Mayo Clinic Perspectives Maurice E. Sarano 1:30 pm - MR Therapy Trends in the United States (DMR and FMR) 2: Insights from the STS Database James S. Gammie 1:40 pm - MR Therapy Trends in Europe (DMR and FMR): Nontreatment, MitraClip, and Surgery Alec Vahanian 1:50 pm - Discussion with Audience Q&A 2:00 pm - How Often Is MV Repair Done (And What Are the Predictors)? James S. Gammie 2:10 pm - Pros and Cons of Early Surgery in Asymptomatic MR Allan Schwartz 2:20 pm - Long-term Durability of Valve Repair/Replacement Alfredo Trento 2:30 pm - MitraClip for High-Risk DMR: Data and Perspectives Ted Feldman 2:40 pm - MitraClip for Low-Risk DMR: Data and Perspectives Saibal Kar 2:50 pm - DMR Therapies: Case Presentation Michael J. Rinaldi 3:00 pm - Discussion with Audience Q&A Session III. Functional Mitral Regurgitation Controversies Moderators: Paul A. Grayburn, Patrick T. O’Gara Discussants: William T. Abraham, Michael Argenziano, Steven F. Bolling, Olaf Franzen, Samir R. Kapadia, Alfredo Trento 3:10 pm - Nonvalvular Therapies for FMR 1: Revascularization (Efficacy and Patient Selection) Samir R. Kapadia 3:20 pm - Nonvalvular Therapies for FMR 2: CRT William T. Abraham Debate: TODAY, the Non-revascularizable Patient with Severe FMR Should as First-Line Therapy be Treated with. . . . 3:30 pm - Surgery! Steven F. Bolling 3:38 pm - MitraClip! Olaf Franzen 3:46 pm - Medical Therapy (With or Without CRT)! Patrick T. O’Gara 3:54 pm - Recurrent MR After Mitral Valve Surgery or MitraClip in FMR: Frequency, Implications, and Management Options Michael Argenziano 4:04 pm - FMR Therapies: Case Presentation Alfredo Trento Session IV. MitraClip Considerations Moderators: Howard C. Herrmann, Corrado Tamburino Discussants: Olaf Franzen, Linda D. Gillam, James B. Hermiller Jr, Saibal Kar, Wolfgang Schillinger, Robert J. Siegel, Frank E. Silvestry, Frederick G. St. Goar 4:29 pm - Lessons from Imaging: Patient Selection and Procedural Guidance to Optimize MitraClip Outcomes Robert J. Siegel 4:39 pm - Grading MR After the MitraClip (And Valve Interventions in General) Frank E. Silvestry - N o v e m b e r 8 , 2 0 11 4:58 pm - Case Review Lessons from the BVS Program: The Good, the Bad, and the Ugly John A. Ormiston Session II. Degenerative Mitral Regurgitation Controversies Moderators: David H. Adams, Scott Lim Case Presenter: Michael J. Rinaldi Discussants: Ted Feldman, James S. Gammie, Saibal Kar, Allan Schwartz, Alfredo Trento Tuesday 4:46 pm - Special Lecture: BVS in Complex Lesions: First Results from ABSORB Extend Alexandre Abizaid T r a n s c at h e t e r Cardiovascular Therapeutics 4:49 pm - Impact of Residual MR After Mitral Valve Surgery vs. MitraClip Linda D. Gillam 4:59 pm - MitraClip Learning Curve: What Have We Learned from the EU Experience? Olaf Franzen 5:09 pm - MitraClip Use Outside of the Standard EVEREST Clinical and Anatomic Indications Wolfgang Schillinger 5:19 pm - MitraClip Complications (Acute and Chronic): Frequency, Avoidance, and Management Saibal Kar 5:29 pm - How Can the Current Generation MitraClip Be Improved? Frederick G. St. Goar 5:39 pm - Challenging MitraClip Case Presentation James B. Hermiller Jr 5:49 pm - Discussion with Audience Q&A 6:00 pm - Adjourn Translational Research and First-in-Human Studies for Emerging Cardiovascular Technologies 1:00 pm-6:00 Room 125 pm Emerging DES Platforms Moderators: Greg L. Kaluza, Robert S. Schwartz Discussants: Nicolas A.F. Chronos, Elazer R. Edelman, Andrew Farb, Aloke V. Finn, Giulio Guagliumi 1:00 pm - Experimental Strategies, Models, and Challenges in the Evaluation of Emerging DES Platforms (Safety and Efficacy) Nicolas A.F. Chronos 4:14 pm - Discussion with Audience Q&A www.tctconference.com 93 Tuesday, November 8 1:10 pm - Surrogate Endpoints in FIH DES Trials: From OCT Surrogates of Healing to Measures of Efficacy Giulio Guagliumi TAVR Moderator: Eberhard Grube Discussants: Andrew Farb, Aloke V. Finn, E. Murat Tuzcu, John G. Webb, Larry L. Wood 1:20 pm - Evolving Towards Polymer-Free DES Platforms: Balancing Efficacy and Thrombotic Risk Alexandre Abizaid 4:00 pm - A Technological Overview of Emerging Aortic Valve Concepts John W. Karanian 1:30 pm - Do Polymers on Stents Add Risk or Safety? New Experimental Insights Elazer R. Edelman 1:40 pm - Discussion with Audience Q&A 4:10 pm - Experimental Considerations and Challenges in the Validation Process of Percutaneous Valve Technologies 1: From Design to Bench Testing Larry L. Wood Totally Bioabsorbable Scaffolds Moderators: Antoine Lafont, Ron Waksman Discussants: Andrew Farb, Syed Hossainy, Greg L. Kaluza, John A. Ormiston 4:20 pm - Experimental Considerations and Challenges in the Validation Process of Percutaneous Valve Technologies 2: Animal Models Renu Virmani 2:00 pm - Emerging Concepts, Polymer Formulations, and Stent Designs: Do They Address Current Limitations of the Technology? Patrick W. Serruys 4:30 pm - Surrogate Endpoints for the Validation of TAVR Safety and Efficacy in FIH Studies John G. Webb 2:10 pm - Mechanistic Role of Structural Vascular Support: The Good and Bad of Permanent vs. Temporary Scaffolds Syed Hossainy 2:20 pm - Evaluation of Mechanical Integrity and Degradation Patterns of Bioabsorbable Stents in Animal Models Greg L. Kaluza 2:30 pm - Lessons Learned from FIH Bioabsorbable Scaffolds: The Good, the Bad, and the Ugly John A. Ormiston 2:40 pm - Discussion with Audience Q&A Drug Coated Balloons Moderators: Elazer R. Edelman, Juan F. Granada Discussants: Andrew Farb, Michael R. Jaff, Greg L. Kaluza 3:00 pm - DCB Validation Strategies: Bench Testing, In Vivo PK, and Beyond Elazer R. Edelman 3:10 pm - First Generation DCB: Preclinical Indications of Suboptimal Formulation Greg L. Kaluza 4:40 pm - Discussion with Audience Q&A Renal Artery Denervation Therapies Moderators: Krishna J. Rocha-Singh, Horst Sievert Discussants: John W. Karanian, Serge Roussel, Dierk Scheinert, Paul A. Sobotka 5:00 pm - Experimental Pathways for the Evaluation of Perirenal Nerve Distribution, Density, and Quantification Serge Roussel 5:10 pm - Preclinical Investigation of Non-blood Pressure Related Effects of Renal Artery Denervation (Glucose Homeostasis, Ovarian Function, etc.) Paul A. Sobotka 5:20 pm - New Therapeutic Alternatives and Delivery Approaches Horst Sievert 5:30 pm - Clinical Considerations for the Design of FIH Clinical Studies Krishna J. Rocha-Singh 5:40 pm - Discussion with Audience Q&A 6:00 pm - Adjourn 3:20 pm - Second Generation DCB: Improving Dosing, Transfer Uniformity, and Particulate Formation Juan F. Granada 3:30 pm - Selecting the Proper Endpoints in FIH SFA Trials: Imaging Assessment vs. Functional Michael R. Jaff 3:40 pm - Discussion with Audience Q&A 94 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Transradial Angiography and Intervention: From Basic to Advanced 1:00 pm-6:00 Room 134 pm Session I. Transradial Fundamentals I Moderators: Ronald Caputo, Varinder P. Singh Discussants: Francesco Burzotta, Mauricio G. Cohen, Ian C. Gilchrist, Martial Hamon, Samir B. Pancholy, Jennifer A. Tremmel, Zoltan G. Turi 1:00 pm - Historical Perspectives on Transradial PCI: Where We’ve Been and Where We’re Headed Zoltan G. Turi 1:10 pm - Patient Setup and Arterial Access for Right and Left Radial (Including Tests of Radial-Ulnar Patency) Mauricio G. Cohen 1:20 pm - Upper Extremity Venous Access and Procedure Ian C. Gilchrist 1:30 pm - From Wrist to Coronaries: Basics, Managing Loops, Tortuosity, and Spasm Martial Hamon 1:45 pm - Diagnostic and Guide Catheter Choices and Manipulation from the Radial Artery for Native and Graft Vessels Francesco Burzotta 2:00 pm - Hemostasis and Radial Artery Patency Samir B. Pancholy 2:10 pm - Case Presentation: Overcoming Numerous Transradial Problems Jennifer A. Tremmel 2:20 pm - Discussion with Audience Q&A Session II. Transradial Fundamentals II Moderators: Martial Hamon, Tejas Patel Discussants: Vladimir Dzavik, Tift Mann, Ramon Quesada, Stéphane Rinfret, Varinder P. Singh 2:35 pm - Dealing with Complications of the Radial Approach Varinder P. Singh 2:45 pm - Case Presentation: A Major Transradial Vascular Complication Stéphane Rinfret 2:55 pm - Anticoagulation Strategies for Transradial Diagnostic and Interventional Cases Tift Mann 3:05 pm - Transradial Primary PCI: Tips and Tricks for Success Tejas Patel The World’s Premier Interventional Experience TCT2011 Special Sessions SCAI ELM Program in Partnership with ACC and CRF 3:35 pm - Discussion with Audience Q&A 7:00 am-1:00 Room 238 Session III. Advanced Concepts in Transradial PCI Moderators: Olivier F. Bertrand, Sunil V. Rao Discussants: Asim Cheema, Sanjay Kumar Chugh, Douglas G. Fraser, Sudhir Rathore, Alessandro Sciahbasi 3:50 pm - The Sheathless Approach for Transradial PCI Douglas G. Fraser 4:00 pm - Minimizing Radial Artery Injury Sudhir Rathore 4:10 pm - Radiation Exposure: Lessons from the TALENT Trial Alessandro Sciahbasi 4:20 pm - Anticipating Failure: Role of Arm Imaging Prior to Arterial Access Sanjay Kumar Chugh 4:30 pm - The Transradial Learning Curve Asim Cheema 4:40 pm - Discussion with Audience Q&A Session IV. Clincial Investigation in Transradial PCI Moderators: James Nolan, Marco Valgimigli Discussants: Ivo Bernat, Olivier F. Bertrand, Sanjit S. Jolly, Sunil V. Rao 4:55 pm - Lesson from the RIVAL Trial: A Critical Appraisal Sanjit S. Jolly 5:05 pm - A Randomized Trial of Radial vs. Femoral Approaches for Primary PCI Ivo Bernat 5:15 pm - Study of Access Site for Enchancement of PCI for Women (SAFE-PCI for Women) Sunil V. Rao 5:25 pm - The EASY B2B Trial Olivier F. Bertrand 5:35 pm - The REAL Registry and the MATRIX Trial Marco Valgimigli 5:45 pm - Discussion with Audience Q&A 6:00 pm - Adjourn Please note this session is by invitation only. pm Program Year 1, Training Session 2 This program is supported by unrestricted educational grants from ABIOMED, AGA Medical, and GE Healthcare. ELM Faculty Srihari S. Naidu, MD (Chair) Tyrone J. Collins, MD Morton J. Kern, MD Douglas Levy, MD Michael J. Lim, MD William W. O’Neill, MD Matthew J. Price, MD Robert J. Sommer, MD Jonathan M. Tobis, MD George W. Vetrovec, MD Shelley Wood ELM Mentors George G. Dangas, MD, PhD Cindy L. Grines, MD James B. Hermiller Jr, MD Thomas K. Jones, MD Morton J. Kern, MD Alexandra J. Lansky, MD Srihari S. Naidu, MD William W. O’Neill, MD Ramon Quesada, MD Gregg W. Stone, MD ELM Fellows J. Dawn Abbott, MD Mauricio G. Cohen, MD Douglas Drachman, MD Allen Jeremias, MD, MSc Navin K. Kapur, MD Lynn Peng, MD Duane S. Pinto, MD Paul Sorajja, MD Jennifer A. Tremmel, MD Thomas M. Tu, MD 7:00 am - Breakfast 7:25 am - ELM Program Update Srihari S. Naidu 7:30 am - Podium Presentation Skills Training Panel 10:00 am - Intro to Working with the Media Shelley Wood 1:00 pm - Adjourn Japan-US Synergies for Medical Device Innovation: A Harmonization by Doing (HBD) Educational Symposium This session is not CE/CME accredited. 8:00 am-12:00 Room 270 pm Part I. The Japan-US Medical Device Landscape Moderators: Mitchell W. Krucoff, Gary Thompson Discussants: Ashley B. Boam, Andrew Farb, Koji Ikeda, Fumiaki Ikeno, Takeshi Kimura, Paul A. LaViolette, Shigeru Saito, Huay Cheem Tan, Takahiro Uchida - N o v e m b e r 8 , 2 0 11 3:25 pm - Transradial Approach for Unprotected Left Main PCI Vladimir Dzavik 12:00 pm - Roundtable Discussion: Avoiding and Surmounting Obstacles to Leadership Tuesday 3:15 pm - Transradial Approach for Chronic Total Occulsions Stéphane Rinfret T r a n s c at h e t e r Cardiovascular Therapeutics 8:00 am - Uncertainties, Concerns, and the Innovation Landscape: An Industry View Paul A. LaViolette 8:10 am - MHLW/PMDA-US FDA HBD Pilot Program Initiative Ashley B. Boam 8:20 am - Heart Disease Speaks Both Japanese and English: Working Together Is Better for Patients, Better for Industry, Better for Regulators Shigeru Saito 8:30 am - Discussion Part II. Coronary Stent Innovation: Biological Poolability East and West Moderators: Andrew Farb, Shigeru Saito Discussants: Keith D. Dawkins, Rié Fukaya, Fumiaki Ikeno, Mitchell W. Krucoff, Manuela Negoita, Thomas J. Povsic, Huay Cheem Tan, Gary Thompson 9:00 am - Bioabsorbable Stent Platforms: The Vision and New Questions in Eastern and Western Patients Richard J. Rapoza 9:10 am - Endothelial Progenitor Cell Capture: The Vision and New Questions In Eastern and Western Patients Mitchell W. Krucoff 9:20 am - “Japan First”: Single Global Trials and Other Options Rié Fukaya 9:30 am - Discussion 10:30 am - Media Training and Advanced Public Speaking Douglas Levy www.tctconference.com 95 Tuesday, November 8 Part III. Structural Heart Disease and Devices In Japan and United States Moderators: Koji Ikeda, Fumiaki Ikeno Discussants: Jodi Akin, Ashley B. Boam, Andrew Farb, Rié Fukaya, Mitchell W. Krucoff, Manuela Negoita, David G. Reuter, Stanton J. Rowe, Shigeru Saito, Kazuhiro Sase, Huay Cheem Tan, Gary Thompson, Takahiro Uchida 10:00 am - LVAD and Artificial Hearts: Combining Postmarket Safety Information to Support Ongoing Innovation Kazuhiro Sase 10:10 am - TAVR: Similarities and Differences in the United States and Japan Jodi Akin 10:20 am - Percutaneous Therapy for Mitral Regurgitation and Heart Failure: Similarities and Differences In the United States and Japan Fumiaki Ikeno 10:30 am - Discussion Part IV. Peripheral Vascular Intervention, East and West Moderator: Ashley B. Boam Discussants: Peter C. Block, Nabil Dib, Andrew Farb, Neal Fearnot, Rié Fukaya Koji Ikeda, Mitchell W. Krucoff, Manesh R. Patel, Shigeru Saito, Robert Thatcher 11:00 am - Japan-US Study of DES for PAD: Lessons Learned Neal Fearnot 11:10 am - Consensus Definitions in PAD: A Global Need Manesh R. Patel 11:20 am - Regulatory Issues for PAD Devices Rié Fukaya 11:30 am - Discussion 12:00 pm - Adjourn Presentation Theater South 12:30 pm-1:30 pm Santa Rosa Valley (Exhibit Hall) Please see page 150 for the Presentation Theater schedule. Special Twilight Sessions Featured Clinical Research II. Drug-Eluting Stent vs. Stent Studies 6:00 pm-8:00 pm Room 121 Moderators: Stephen G. Ellis, Alan C. Yeung Discussants: Bernard R. Chevalier, Nicolas A.F. Chronos, Jose M. de la Torre Hernandez, Jorge Gaspar, Christoph A. Kaiser, Young-Hak Kim, Pedro A. Lemos, Tift Mann 6:00 pm - LONG-DES IV: A Prospective, Randomized Trial of Zotarolimus-Eluting Stents and Sirolimus-Eluting Stents in Patients with Long Coronary Artery Lesions Seung-Jung Park 6:10 pm - Discussion with Audience Q&A 6:15 pm - LEADERS Four-Year: A Prospective, Randomized Trial of a Bioabsorbable Polymer-Based Biolimus-Eluting Stent vs. a Durable Polymer-Based SirolimusEluting Stent Thomas A. Ischinger 6:25 pm - Discussion with Audience Q&A 6:30 pm - SORT OUT IV 2-Year: A Prospective, Randomized Trial of an Everolimus-Eluting Stent and a Sirolimus-Eluting Stent Lisette Okkels Jensen 6:40 pm - Discussion with Audience Q&A 6:45 pm - PRECOMBAT-2: A Multicenter Case-Controlled Registry of EverolimusEluting Stents vs. Sirolimus-Eluting Stents in Patients with Unprotected Left Main Disease Seung-Jung Park 6:55 pm - Discussion with Audience Q&A 7:00 pm - XIENCE Prime: A Prospective, Multicenter, Single-Arm Study of a New Cobalt Chromium Everolimus-Eluting Stent Marco A. Costa 7:10 pm - Discussion with Audience Q&A 7:15 pm - RIBS III: A Prospective, Multicenter, Registry of the Use of Same or Different Stents After Coronary Drug-Eluting Stent Restenosis Fernando Alfonso 7:25 pm - Discussion with Audience Q&A 7:30 pm - APICE-OCT: A Prospective, Multicenter, Randomized Trial of Zotarolimus-Eluting Stents and EverolimusEluting Stents in Patients with Acute Coronary Syndromes Alaide Chieffo 7:40 pm - Discussion with Audience Q&A 7:45 pm - A Prospective, Multicenter, Randomized Trial of the Early Healing of Four Types of Stents Assessed by Optical Coherence Tomography Ladislav Groch 7:55 pm - Discussion with Audience Q&A 8:00 pm - Adjourn How to Treat Complex Lesions This session is not CE/CME accredited. 6:00 pm-8:00 pm Room 114 Moderator: Yang-Soo Jang Discussants: In-Ho Chae, Yun-Kyeong Cho, Woong-Chul Kang, Byoung-Kwon Lee, Jong-Seon Park, Sang-Yeob Yim 6:00 pm - Introduction Yang-Soo Jang Session I. Complex Multivessel Disease PCI in a Diabetic Patient 6:05 pm - Case Presentation Yun-Kyeong Cho 6:10 pm - How Would I Treat? Sang-Yeob Yim, Byoung-Kwon Lee 6:30 pm - How Did I Treat? Yun-Kyeong Cho 6:40 pm - Discussion 6:50 pm - Consensus Yang-Soo Jang Session II. Complex Disease PCI in a STEMI Patient 6:55 pm - Case Presentation Woong-Chul Kang 7:00 pm - How Would I Treat? In-Ho Chae, Jong-Seon Park 7:20 pm - How Did I Treat? Woong-Chul Kang 7:30 pm - Discussion 7:40 pm - Consensus Yang-Soo Jang 96 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 8:00 pm - Adjourn 6:00 pm-8:00 pm Room 113 Moderators: Run-Lin Gao, Martin B. Leon, Gregg W. Stone Discussants: YunDai Chen, Antonio Colombo, Eberhard Grube, Ajay J. Kirtane, Shuzheng Lu, Roxana Mehran, Shubin Qiao, Bo Xu, Ruiyan Zhang 7:53 pm - Tips and Tricks in Management of Severe PCI Complications Ruiyan Zhang 8:00 pm - Adjourn Challenge I. How to Treat Difficult Bifurcation Lesions 6:00 pm - A Complex True Bifurcation Lesion Case Presenter: Weimin Wang 6:00 pm - Opening Remarks Juan F. Granada 6:07 pm - Discussion 6:02 pm - Interventional Cardiology in the Russian Federation: “The Last Decade” Bagrat Alekyan Challenge II. How to Treat a Complex CTO Lesion 6:24 pm - Retrograde CTO Angioplasty Case Presenter: Lei Ge 6:31 pm - Discussion 6:41 pm - Tips and Tricks in CTO Angioplasty Yaling Han Challenge III. How to Treat a Treacherous Left Main Lesion by the Transradial Approach 7:05 pm - Tips and Tricks in Left Main Stenting by the Transradial Approach Yuejin Yang 6:51 pm - Case Presentation: Atypical Use of Occluders Alexander G. Osiev Challenge IV. How to Manage a Difficult Patient with STEMI 6:56 pm - Mini-Lecture: Indications and Tips and Tricks with Occluders Bagrat Alekyan 7:36 pm - Nightmare in the Cath Lab Case Presenter: Haichang Wang Please see page 150 for the Evening Programs schedule. 6:29 pm - Case Presentation: Difficult LAA Occlusion Saibal Kar 6:41 pm - Discussion Challenge V. How to Treat a Major Complication During PCI pm -10:00 pm 6:19 pm - Discussion 6:55 pm - Discussion 7:29 pm - Tips and Tricks During Primary PCI for STEMI Hongbing Yan 7:00 6:12 pm - Mini-Lecture: Device Selection and Tips and Tricks for ASD Closure Ziyad M. Hijazi 6:34 pm - Mini-Lecture: Tips and Tricks in LAA Deployment William A. Gray 7:19 pm - Discussion Evening Programs 6:05 pm - Case Presentation: Atrial Septal Defect Alexey Protopopov 6:48 pm - Distal LM Bifurcation Case Presenter: Guosheng Fu 7:12 pm - STEMI with Large, Refractory Thrombus Burden Case Presenter: Lefeng Wang 7:47 pm - Discussion 8:00 pm - Adjourn Partnership Session: TCT Russia: Focused Session on Endovascular and Structural Heart Disease 6:00 pm-8:00 pm Room 122 Moderators: Bagrat Alekyan, Juan F. Granada, Gary S. Mintz Discussants: Vladimir Ganyukov, Barry T. Katzen, Zaza Kavteladze, Alexander Nikanorov, Alexander G. Osiev, Alexey Protopopov, Brian Whisenant 6:17 pm - Tips and Tricks in Bifurcation PCI Michael Kang-Yin Lee 7:40 pm - Mini-Lecture: The Complex SFA Environment: Biomechanics, Biological Considerations, and Beyond Alexander Nikanorov - N o v e m b e r 8 , 2 0 11 Partnership Session: CIT in Partnership with TCT: Challenging Cases in Clinical Practice 7:43 pm - Discussion Tuesday 7:45 pm - Conclusions Yang-Soo Jang T r a n s c at h e t e r Cardiovascular Therapeutics 7:03 pm - Discussion 7:13 pm - Case Presentation: Percutaneous Repair of Thoracic Aortic Aneurysms Vladimir Ganyukov 7:18 pm - Mini-Lecture: Tips and Tricks During TAA Repair Sergey A. Abugov 7:25 pm - Discussion 7:35 pm - Case Presentation: A Complex Case of SFA Intervention Zaza Kavteladze www.tctconference.com 97 C A R D I O VA S C U L A R RESEARCH F O U N D AT I O N Skirball Research Center Redefining Preclinical Cardiovascular Translational Research The goal of translational The Jack H. Skirball Center for Cardiovascular Research (SCCR) is a state-of-the-art research is to bring an innovative facility dedicated to the investigation of novel concepts, treatments, and devices. concept into the arena of human Our team of interventionalists, surgeons, and pathologists guide early ideas and clinical trials. Our scientists and physicians develop the strategies needed to navigate and facilitate this process. inventions through comprehensive research programs in order to introduce practical clinical therapies to patients. SCCR is the starting point for technological advances that will ultimately improve the lives of those suffering from cardiovascular disease and is defined by innovative thinking. Translational Research Research Cores • Biotechnology validation • Emerging vascular interventions • Independent research • Applied cardiovascular imaging • Professional education • Regenerative interventional therapies • Invention • Interventional vascular biology • Emerging cardiovascular concepts Visit us at the Partnership Pavilion on the first floor of Moscone North. The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Major Halls Main Arena............................................................................................... 100 How to Treat Theater: Coronary Artery Disease....................................... 101 How to Treat Theater: Endovascular and Structural Heart Disease.......... 102 Challenging Case Multiplex Challenging Case Theater........................................................................ 103 International Society-Sponsored Case Theater........................................ 103 Maintenance of Certification (MOC) Course........................... 104 Morning Spotlight Sessions Core Training Curriculum in Clinical Research.......................................... 104 Deep Dive: Stroke Prevention Therapies.................................................. 105 Innovative Surgical Techniques and Technologies.................................... 106 International Debating Chamber: Interventional Cardiology on Trial......... 106 Presentation Theaters..................................................................... 155 TCT for Surgeons............................................................... 106, 111, 114 Lunchtime Sessions Hot Topics................................................................................................ 107 Learn the Technique................................................................................. 109 Afternoon Spotlight Sessions Aortic Endografts and Aneurysm Repair ................................................. 111 Integrating IVUS and FFR to Improve PCI Outcomes............................... 112 Next Generation Transcatheter Mitral Valve Therapies............................. 112 Special Twilight Sessions Clinical Cardiovascular Genetics and the Era of Personalized Medicine................................................................... 114 Focus on India: Interactive Case Review and Panel Discussion............... 115 Korean Interventional Summit.................................................................. 116 Special Circulation Journal Session: The Most Important Interventional Papers from the Last Year.................................................. 116 san francisco, ca Partnership Session: JIM at TCT.............................................................. 115 · Featured Clinical Research III. Drug-Eluting Stents, Drug-Coated Balloons, and PCI Pharmacology....................................... 115 November 9, 2011 Surgical, Interventional, and Hybrid Procedures (Part 2): Valvular and Structural Heart Disease...................................................... 114 the Moscone Center Optimizing Use of Today’s Antithrombotic and Antiplatelet Drugs in ACS, PCI, and Atrial Fibrillation.................................................. 113 Wednesday Breakfast Meetings........................................................................... 152 Evening Programs.............................................................................. 156 www.tctconference.com 99 Wednesday, November 9 Breakfast Meetings 7:00 am -8:00 am Please see page 152 for the Breakfast Meetings schedule. Main Arena Moderators: Martin B. Leon, Gregg W. Stone Plenary Session I. Live Cases I Live Case Moderator: Martin B. Leon Live Case Co-Moderator: Martyn R. Thomas Live Case Discussants: Alaide Chieffo, Ulrich J. Gerckens, Sheldon Goldberg, John McB. Hodgson, Thomas K. Jones, Takeshi Kimura, Jan Kovac, John A. Ormiston, Jeffrey J. Popma, E. Murat Tuzcu, Stephen G. Worthley 8:00 am - St Thomas’ Hospital London, United Kingdom 8:45 am - NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Plenary Session II. Transcatheter Aortic Valve Replacement Moderators: Robert O. Bonow, Michael J. Mack Discussants: Blase A. Carabello, Eberhard Grube, D. Craig Miller, Allan Schwartz 9:30 am - Spotlight Lecture: Complications After TAVR: Achilles’ Heel or Manageable in the Future? Martin B. Leon TCT Interventional Corner I. The Future of TAVR: Cautious vs. Rapid Adoption Discussants: Craig R. Smith, E. Murat Tuzcu 9:45 am - A Surgeon’s Perspective Craig R. Smith 9:55 am - The Interventionalist’s Viewpoint E. Murat Tuzcu 10:05 am - Discussion and Rebuttal 10:15 am - Synthesis Patrick T. O’Gara Plenary Session III. TCT 2011 Revolutions Moderator: Gregg W. Stone 10:20 am - TCT 2011 Welcome Martin B. Leon, Gregg W. Stone program · Focus on PCI Pharmacology and Stent Thrombosis II 12:15 pm - RAPID GENE: A Prospective, Randomized Trial of Prasugrel vs. Clopidogrel in CYP2C19*2 Carriers Identified by Rapid Point-of-Care Genotyping 10:40 am - TCT 2011 Keynote Address: The Future of Humankind Michio Kaku Plenary Session IV. TCT 2011 Career Achievement Award 8:00 am-6:00 pm Esplanade Ballroom 100 10:25 am - Incidence and Epidemiology of Cardiovascular Disease: A National (and International) Success Story Lee Goldman 11:15 am - Presentation of the TCT 2011 Career Achievement Award Award Presenter: Martin B. Leon Award Recipient: Eric J. Topol Plenary Session V. Late Breaking Clinical Trials and First Report Investigations I Moderator: E. Magnus Ohman Discussants: Dominick J. Angiolillo, Laurent Bonello, David P. Faxon, Paul A. Gurbel, Neal S. Kleiman, David F. Kong, Roxana Mehran, Shamir R. Mehta, Michelle O’Donoghue, Derek So, Gregg W. Stone, Jurrien M. Ten Berg, Eric J. Topol, Dietmar Trenk Focus on PCI Pharmacology and Stent Thrombosis I 11:30 am - ADAPT-DES: A Large-Scale, Prospective, Multicenter Registry Examining the Relationship of Platelet Responsiveness to Stent Thrombosis After DES Implantation Gregg W. Stone 11:40 am - DESERT: A Large-Scale, Multicenter, Case-Controlled Study Examining the Predictors of Stent Thrombosis Ron Waksman 11:50 am - PARIS: A Large-Scale, Prospective, Multicenter Registry Studying the Patterns of and Reasons for Nonadherence to Antiplatelet Agents in Stented Patients Roxana Mehran 12:00 pm - Roundtable Discussion: Strengths, Limitations, and Implications of These Studies T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Derek So 12:25 pm - TRIGGER-PCI: A Prospective, Randomized Trial of Prasugrel vs. Clopidogrel in ClopidogrelHyporesponsive Patients with Stable Ischemic Heart Disease Undergoing Percutaneous Coronary Intervention Dietmar Trenk 12:35 pm - BRIDGE: A Prospective, Double-Blind, Multicenter, Randomized Placebo-Controlled Trial of Intravenous Cangrelor in Patients Awaiting Surgery Dominick J. Angiolillo 12:45 pm - Roundtable Discussion: Strengths, Limitations, and Implications of These Studies Plenary Session VI. Live Cases II Live Case Moderator: Gregg W. Stone Live Case Co-Moderator: Patrick W. Serruys Live Case Discussants: W. Randolph Chitwood Jr, Alain G. Cribier, Marc D. Feldman, Eberhard Grube, Ajay J. Kirtane, Jean-Claude Laborde, Michael J. Mack, Ian T. Meredith, Jonathan M. Tobis, Olaf Wendler, Stephan Windecker 1:00 pm - St. Paul’s Hospital/University of British Columbia Vancouver, Canada 1:45 pm - University of Colorado Health Sciences Center Denver, CO Plenary Session VII. Coronary Revascularization Updates Moderators: Bernard J. Gersh, Joseph F. Sabik Discussants: William E. Boden, Ralph G. Brindis, David J. Cohen, Mark Andrew Hlatky, Ajay J. Kirtane, David J. Maron, Harry R. Phillips, David Taggart The World’s Premier Interventional Experience TCT2011 2:30 pm - Strengths, Limitations, and the Raison d’Être for Appropriateness Criteria Manesh R. Patel 2:50 pm - Discussion TCT Interventional Hot Topic II. Chronic Cerebrospinal Venous Insufficiency (CCSVI) for Multiple Sclerosis 5:30 pm - Chronic Cerebrospinal Venous Insufficiency (CCSVI) for Multiple Sclerosis Michael D. Dake 5:45 pm - Current Perspectives and Future Expectations Barry T. Katzen 5:50 pm - Discussion 6:00 pm - Adjourn 3:05 pm - Spotlight Lecture: Clinical Decision-Making in Patients with Multivessel and Left Main Disease David E. Kandzari 3:20 pm - Discussion Plenary Session VIII. Live Cases III Live Case Moderator: Martin B. Leon Live Case Co-Moderator: Hans Krankenberg Live Case Discussants: Steven R. Bailey, Rafael Beyar, Giancarlo Biamino, Bernard R. Chevalier, Run-Lin Gao, Michel Henry, Lindsay S. Machan, Ashok Seth, Ron Waksman, Michael H. Wholey, Jay S. Yadav 3:30 pm - University of California, Davis Medical Center Sacramento, CA 4:15 pm - Cedars-Sinai Medical Center Los Angeles, CA Plenary Session IX. Endovascular Horizons Moderators: Barry T. Katzen, Jeffrey W. Olin Discussants: Michael R. Jaff, Lindsay S. Machan, Harry R. Phillips, Stephen R. Ramee, Krishna J. Rocha-Singh, Paul A. Sobotka, Adam Witkowski TCT Interventional Hot Topic I. Transcatheter Renal Nerve Denervation for Refractory Hypertension 5:00 pm - Transcatheter Renal Nerve Denervation for Refractory Hypertension Henry Krum 5:15 pm - Current Perspectives and Future Expectations Murray D. Esler How to Treat Theater: Coronary Artery Disease 8:00 am-6:00 Hall D pm Left Main and Bifurcation Intervention I Moderator: Patrick W. Serruys Co-Moderator: Stephen G. Ellis 8:00 am - Bifurcation (Left Main and Non-Left Main) Technique 1: What Have We Learned from Randomized Trials? Leif Thuesen 8:15 am - Bifurcation (Left Main and Non-Left Main) Technique 2: What Have We Learned from Clinical Experience? Antonio Colombo Live Cases: Left Main and Bifurcation I Live Case Moderator: Patrick W. Serruys Live Case Co-Moderator: Stephen G. Ellis Live Case Discussants: Didier Carrie, Michael J. Cowley, John S. Douglas Jr, Dietmar H. Glogar, Michalis Hamilos, Jens Flensted Lassen, Michael S. Lee, Alfredo Rodriguez, Teguh Santoso 8:30 am - ICPS Institut Hospitalier Jacques Cartier Massy, France 9:15 am - Cedars-Sinai Medical Center Los Angeles, CA 10:00 am - Discussion: What Have We Learned from These Cases? Left Main and Bifurcation Intervention II Moderator: Antonio Colombo Co-Moderator: David G. Rizik 10:15 am - Integrated Clinical Trial Insights into the Appropriateness of Left Main Intervention Patrick W. Serruys 10:30 am - Assessing Patients for Left Main PCI: Practicalities and Limitations of Risk Scores Corrado Tamburino Live Cases: Left Main and Bifurcation II - N o v e m b e r 9 , 2 0 11 2:40 pm - The Appropriateness of PCI Procedures: Insights, Limitations and Recommendations from a Registry-Based Analysis Paul S. Chan 5:20 pm - Discussion Wednesday TCT Interventional Corner II. The Appropriate Use of Appropriateness Criteria T r a n s c at h e t e r Cardiovascular Therapeutics Live Case Moderator: Antonio Colombo Live Case Co-Moderator: David G. Rizik Live Case Discussants: Francesco Burzotta, Kenneth Chin, Andrejs Erglis, Daljeet S. Gambhir, Jorge Gaspar, Ran Kornowski, Shu-Kin Li, Keith G. Oldroyd, Marco Valgimigli 10:45 am - St Thomas’ Hospital London, United Kingdom 11:30 am - NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY 12:15 pm - Discussion: What Have We Learned from These Cases? 12:30 pm - Break Chronic Total Occlusion I Moderator: Kenneth Chin Co-Moderator: Shigeru Saito 1:30 pm - CTO Clinical Decision-Making: Incorporating Myocardium at Risk, Ischemia, and Completeness of Revascularization into a Framework to Guide Revascularization Gerald S. Werner 1:45 pm - Emerging Antegrade Tools, Techniques, and Approaches for CTO Recanalization and Procedural Success J. Aaron Grantham Live Cases: Chronic Total Occlusion I Live Case Moderator: Gerald S. Werner Live Case Co-Moderator: Carlo Di Mario Live Case Discussants: Mauro Carlino, Keiichi Igarashi, Toshiya Muramatsu, Robert T. Pyo, Sudhir Rathore, Shigeru Saito, Georgios Sianos, Bradley H. Strauss, Craig A. Thompson 2:00 pm - NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY www.tctconference.com 101 Wednesday, November 9 3:30 pm - Discussion: What Have We Learned from These Cases? Chronic Total Occlusion II Moderator: David E. Kandzari Co-Moderator: S. Chiu Wong 3:45 pm - Emerging Retrograde Tools, Techniques, and Approaches for CTO Recanalization and Procedural Success Craig A. Thompson 4:00 pm - Complications of Complex PCI: Contrast Nephropathy, Perforations, Vascular Compromise, and Radiation Toxicity Roxana Mehran Live Cases: Chronic Total Occlusion II Live Case Moderator: David E. Kandzari Live Case Co-Moderator: S. Chiu Wong Live Case Discussants: Yaron Almagor, Alfredo R. Galassi, Jonathan M. Hill, Jacques J. Koolen, Ashwin Balachand Mehta, Sunao Nakamura, Stéphane Rinfret, R. Michael Wyman, Masahisa Yamane 4:15 pm - Toyohashi Heart Center Toyohashi, Japan 5:45 pm - Discussion: What Have We Learned from These Cases? 6:00 pm - Adjourn How to Treat Theater: Endovascular and Structural HEart Disease 8:00 am-6:00 Hall D pm Transcatheter Valve Therapies I Moderator: Thomas Walther Co-Moderator: Ganesh Manoharan 8:00 am - Aortic Stenosis: Pathology, Pathophysiology, Natural History, Balloon Aortic Valvuloplasty, and Surgical Therapies Patrick T. O’Gara 8:15 am - TAVR 1: Case Selection Considerations: Anatomic and Clinical Factors Samir R. Kapadia 102 program · Live Cases: Transcatheter Valve Therapies I Live Case Moderator: Thomas Walther Live Case Co-Moderator: Ganesh Manoharan Live Case Discussants: Stephen J.D. Brecker, Gill L. Buchanan, Gregory P. Fontana, Azeem Latib, Michael Kang-Yin Lee, Brij Maini, Oscar A. Mendiz, Wesley R. Pedersen, Corrado Tamburino, William A. Zoghbi 8:30 am - St. Paul’s Hospital/University of British Columbia Vancouver, Canada 9:15 am - St Thomas’ Hospital London, United Kingdom 1:45 pm - Navigating Femoropopliteal Intervention: So Many Choices, So Little Data Thomas Zeller Live Cases: Iliac and SFA Live Case Moderator: Gary M. Ansel Live Case Co-Moderator: Krishna J. Rocha-Singh Live Case Discussants: Herbert D. Aronow, Mark C. Bates, Fernando Cura, Lawrence A. Garcia, Erich Minar, Alex Powell, Luigi Salemme, David P. Slovut, Craig M. Walker 10:00 am - Discussion: What Have We Learned from These Cases? 2:00 pm - University of California, Davis Medical Center Sacramento, CA Transcatheter Valve Therapies II 2:45 pm - Auckland City Hospital Auckland, New Zealand Moderator: Joseph E. Bavaria Co-Moderator: Todd M. Dewey 10:15 am - TAVR 2: Results of TAVR in High Surgical Risk and Inoperable Patients Samir R. Kapadia 10:30 am - TAVR 3: Next Generation TAVR Systems and Novel Accessory Devices (to Reduce Complications) Eberhard Grube Live Cases: Transcatheter Valve Therapies II Live Case Moderator: Joseph E. Bavaria Live Case Co-Moderator: Craig R. Smith Live Case Discussants: Michael J. Davidson, Victor Guetta, Rebecca Tung Hahn, Petr Kala, Axel Linke, Neil E. Moat, Igor F. Palacios, David Paniagua, Augusto D. Pichard 10:45 am - St. Paul’s Hospital/University of British Columbia Vancouver, Canada 11:30 am - ICPS Institut Hospitalier Jacques Cartier Massy, France 12:15 pm - Discussion: What Have We Learned from These Cases? 3:30 pm - Discussion: What Have We Learned from These Cases? Aortic and Renal/ Mesenteric Intervention Moderator: John H. Rundback Co-Moderator: Mark W. Burket 3:45 pm - Renal Intervention Status Before the CORAL Results: The “Prequel” Michael R. Jaff 4:00 pm - EVAR Indications, Patient Selection, and Outcomes: What Are the Remaining Controversies? Roger M. Greenhalgh Live Cases: Aortic and Renal/Mesenteric Live Case Moderator: John H. Rundback Live Case Co-Moderator: Mark W. Burket Live Case Discussants: Robert M. Bersin, Alessandro S. Bortone, Hugo F. Londero, James F. McKinsey, Takao Ohki, Juan C. Parodi, Rahul S. Patel, On Topaz, Marco V. Wainstein 12:30 pm - Break 4:15 pm - University of California, Davis Medical Center Sacramento, CA Iliac and SFA Intervention 5:00 pm - Auckland City Hospital Auckland, New Zealand Moderator: Gary M. Ansel Co-Moderator: Craig M. Walker 5:45 pm - Discussion: What Have We Learned from These Cases? 1:30 pm - The Conversion from Surgical to Endovascular Revascularization for Iliac Occlusive Disease Is Nearly Complete: What Are the Remaining Challenges? Hans Krankenberg 6:00 pm - Adjourn T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 Challenging Case Theater pm Endovascular I Moderators: Greg Mishkel, Jeffrey W. Olin Discussants: Herbert D. Aronow, James P. Burke 9:00 am - Use of a Reentry Catheter in Chronic Total Occlusion of Infrarenal Aorta Taehoon Kim 9:12 am - Innovative Technique to Facilitate Endovascular Repair of Giant Arch and Descending Aortic Aneurysms George Joseph 9:24 am - Double Distal Protection for Carotid and Vertebral Arteries in a Brachiocephalic Artery Occlusion Eijiro Hayashi 9:36 am - Bilateral Carotid Stenting by Transradial Approach Luis Fernando Campos 9:48 am - Alternative Contrast Media for Endovascular Therapy of a Patient with Kidney Disease Iwaki Taku Complex and Unusual Interventions Moderators: Graham A. Cassel, Raimund A. Erbel Discussants: Pawel E. Buszman, Nicola Corvaja 10:00 am - Multiorgan Resuscitation Using Multimodality Support Benjamin Yang 10:12 am - Have a Closer Look. . . . Jaclyn Chi Lin Chan 10:24 am - Hemodynamic Support in Cardiogenic Shock Complicated By Severe Aortic Stenosis Behnam Tehrani 10:36 am - To Pull or Not to Pull . . . Too Hard on a Wire Narasimharaj Rajendra 10:48 am - A Novel Approach to IVC Filter Thrombosis Rahul Sakhuja Thrombotic Complications Moderators: Theodore A. Bass, Michael J. Cowley Discussants: John A. Ambrose, Muzaffer Degertekin 11:12 am - Practicing Safe Stenting: Simultaneous Embolic Protection In Bifurcation Vein Graft Intervention Eric Fuh 11:24 am - The Use of Nicorandil in a Case of No Reflow in RCA with Occluded LAD Seung Uk Lee 11:36 am - A Fractured Balloon Interrupting LAD Flow Jae-Hwan Lee 11:48 am - Acute Occlusion in a Giant Coronary Aneurysm Treated with Covered Stents Katsuyuki Hasegawa 12:00 - Break Acute Myocardial Infarction Moderators: Kirk N. Garratt, Manel Sabate Discussants: Daniel J. Blackman, Robert J. Freedman Jr 2:00 pm - Myocardial Infarction Following Intracardiac Injection of Metallic Mercury Izabela Wojtkowska 2:12 pm - Retrieval of a Ruptured and Detached Balloon During Primary PCI Vit Reznicek 2:24 pm - Cardiogenic Shock in a Postpartum Woman Gianfranco Aprigliano 3:48 pm - Exploring New Interventional Frontiers in Congenital Heart Disease Werner Budts Chronic Total Occlusion I Moderators: Kevin J. Beatt, Angela Hoye Discussants: M. Nicholas Burke, Oktay Ergene 4:00 pm - Modified Rendezvous Technique for CTO During Retrograde PCI Bin Zhang 4:12 pm - Retrograde Approach for a CTO via a Gastroepiploic Artery Graft Yoshiaki Mibiki 4:24 pm - Coronary Perforation During Antegrade and Retrograde Subintimal Tracking for Right Coronary CTO Yuichi Ujiie 4:36 pm - Only 10 ml Contrast Media Used for CTO PCI of the RCA Using Retrograde Approach in a Patient with Chronic Kidney Disease Ryosuke Kametani 4:48 pm - Kissing-Wire Technique for a Totally Occluded Ostial LAD with Retrograde Approach from a SVG in the Descending Aorta Masashi Fujino 5:00 pm - Adjourn International Society-Sponsored Case Theater 8:00 am-6:00 Hall D pm 2:36 pm - Percutaneous Device Closure of Left Ventricular Free Wall Rupture Harinder Bali The Intersection of PCI and CABG Sponsored by the Belgian Working Group of Interventional Cardiology 2:48 pm - Failed Repeated Thrombolysis Requiring Left Ventricular Assist Device Gilbert Tang Moderators: Suzanne Pourbaix, Glenn Van Langenhove Adult Congenital Heart Disease I Moderators: Ralf J. Holzer, John F. Rhodes Discussants: Bruce Bowers, Jon C. George 3:00 pm - Transcatheter Closure of a Large ASD from the Femoral Vein in a Patient with Budd-Chiari Syndrome Shreepal Jain 3:12 pm - Percutaneous Closure of an Aorto-Pseudoaneurysm Fistula and Left Ventricular Pseudoaneurysm Josef Toussaint 3:24 pm - Management of Catheter-Associated Right Atrial Thrombus During Percutaneous Mitral Valve Paravalvular Leak Closure Ethan Korngold 3:36 pm - Transjugular Tricuspid Valve-in-Valve Replacement Hellmuth Weich - N o v e m b e r 9 , 2 0 11 9:00 am-5:00 Hall D 11:00 am - Mechanical and Pharmacological Approach to Extensive Saphenous Vein Graft Thrombus Ethan Korngold Wednesday Challenging Case Multiplex T r a n s c at h e t e r Cardiovascular Therapeutics 9:00 am - Case 1: CABG After Failed/ Complicated PCI Claude Hanet 9:15 am - Case 2: PCI/TAVR for When CABG/AVR Is Impossible Walter Desmet 9:30 am - Case 3: PCI for Late CABG Failure Paul Vermeersch 9:45 am - Case 4: Mixed Revascularization by CABG and PCI Erwin Schroeder PCI Complications Sponsored by the Chinese Society of Cardiology Moderator: Run-Lin Gao Discussants: Xianghua Fu, Yaling Han, Yuejin Yang, Yujie Zhou www.tctconference.com 103 Wednesday, November 9 10:00 am - Case 1: Osteofascial Compartment Syndrome After PCI via Transradial Approach Lang Li 10:15 am - Case 2: Simple Lesion, Complicated Result Jian Liu 10:30 am - Case 3: The Trap of RCA Stenosis with Aneurysmal Dilation Xuebo Liu 10:45 am - Case 4: Stent Loss During LAD PCI: Cause and Treatment Qi Zhang Navigating Complex Coronary Bifurcation Lesion Treatment Sponsored by the Nordic-Baltic Study Group of Interventional Cardiology Moderator: Leif Thuesen Discussants: Knut Endresen, Jens Flensted Lassen, Terje K. Steigen, Simon Walsh 11:00 am - Case 1: Threatened Occlusion of the Main Vessel During Two-Stent Bifurcation Procedure Jaakko Niemela Lead Discussant: Simon Walsh Moderators: Dariusz Dudek, Adam Witkowski Discussants: Robert J. Gil, Maciej Lesiak, Andrzej J. Ochala, Krzysztof Reczuch This session is not CE accredited for nurses. 3:30 pm - Case 3: Valve-in-Valve Technique for Optimization of a Complicated CoreValve TAVR Case Maciej Dabrowski 3:45 pm - Case 4: TAVR and Complex PCI in a Patient with Breast Cancer Pawel Kleczynski Complications in Interventional Cardiology Sponsored by the Swedish Working Group on PCI, Swedish Society of Cardiology 4:00 pm - Case 1: Cardiogenic Shock Induced by a Pacemaker Implant in a Patient with Multiple CTOs Matthias Götberg 11:45 am - Case 4: When a Chronic Total Occlusion Turns into a Bifurcation Lesion Evald H. Christiansen Lead Discussant: Terje K. Steigen 4:15 pm - Case 2: From an LAD Lesion to a Left Main Complication Jason Stewart 2:00 pm - Case 1: When It Rains, It Pours Christoph A. Kaiser 2:15 pm - Case 2: Vascular Nightmare Following TAVR Stephane Noble 2:30 pm - Case 3: Stable—But for How Long? Peter Wenaweser 2:45 pm - Case 4: Valve in Ring: Disappointing Result or Not? Roberto Corti program · 6:00 pm - Adjourn 3:15 pm - Case 2: Bifurcation Stenting in a Patient with NSTE-ACS and Pulmonary Edema Aleksander Araszkiewicz 11:30 am - Case 3: Using FFR for DecisionMaking of Sidebranch Stenting Indulis Kumsars Lead Discussant: Knut Endresen Moderators: Stéphane Cook, Franz R. Eberli, Giovanni B. Pedrazzini, Ulrich Sigwart, Philip M. Urban 5:45 pm - Case 4: Complicated RCA CTO Rosli Mohd Ali Maintenance of Certification (MOC) Course Moderator: Goran K. Olivecrona Discussants: Mikael Danielewicz, Lars Hellsten, Ulf Jens Jensen, Thomas Kellerth Valve Complications Sponsored by the Swiss Society of Cardiology 5:30 pm - Case 3: Occlusion of the Abdominal Aorta After Coronary Angiography Yudi Her Oktaviano 3:00 pm - Case 1: Intraaortic Balloon Pump Counterpulsation During PCI in a Very High-Risk Patient with NSTE-ACS Radoslaw Parma 11:15 am - Case 2: Minimizing Multiple Stent Layers in Bifurcation Stenting Miroslaw Ferenc Lead Discussant: Jens Flensted Lassen 12:00 pm - Break 104 Challenging Cases in Coronary and Aortic Valve Interventions Sponsored by the Association on Cardiovascular Interventions of the Polish Cardiac Society 4:30 pm - Case 3: Cardiac Arrest in a Patient Transferred Between PCI Centers with a Wire Across the Lesion Jacob Odenstedt 4:45 pm - Case 4: Takotsubo Cardiomyopathy: Hemodynamic Compromise When Treated as a Conventional Acute Coronary Syndrome Berglind Libungan PCI Complications: Nightmare Scenarios Sponsored by the ASEAN Federation of Cardiology Moderators: Kenneth Chin, Thosaphol Limpijankit Discussants: Sarana Boonbaichaiyapruck, Teguh Santoso, Wasan Udayachalerm 5:00 pm - Case 1: Thrombus During Coiling of a Coronary Pulmonary Fistula Timothy C. Dy 5:15 pm - Case 2: Stuck Rotablator Burr— Really Stuck! Wacin Buddhari T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 8:00 am-2:00 Room 103 pm 8:00 am - Welcome and Introduction George D. Dangas 8:05 am - Interventional Cardiology 2011 Update Module Review Moderator: Tayo A. Addo Discussants: Emmanouil S. Brilakis, Duane S. Pinto 10:00 am - Break 10:15 am - Interventional Cardiology 2010 Update Module Review Moderators: Steven R. Bailey, Charles E. Chambers Discussants: Tayo A. Addo, Emmanouil S. Brilakis 12:00 pm - Interventional Cardiology 2009 Update Module Review Moderators: Emmanouil S. Brilakis, George D. Dangas Discussants: Tayo A. Addo, Charles E. Chambers 2:00 pm - Adjourn Morning Spotlight Sessions Core Training Curriculum in Clinical Research 8:00 am-12:00 Room 134 pm Session I. How to Establish and Maintain a Successful Research Program Moderators: David A. Cox, Giora Weisz Discussants: Ravit Barkama, Bruce R. Brodie, Kate Dalton, Timothy D. Henry, James B. Hermiller Jr, David E. Kandzari, Roxana Mehran, Lauren T. Privitera, Ron Waksman 8:00 am - Welcome and Introduction: Objectives of the Section Giora Weisz The World’s Premier Interventional Experience TCT2011 8:15 am - The Guiding Principles: Standards to Be Followed Ravit Barkama 8:35 am - The Perfect Site: Enroll More, Keep Quality and Morale High, and Costs Down! James B. Hermiller Jr 8:50 am - Investigator-Initiated Research: How Do You Start? Ron Waksman 9:00 am - Industry-Sponsored Research: How Do You Succeed? David E. Kandzari 11:20 am - Muddy Waters: Intent-to-Treat vs. Per-Protocol Analyses Ajay J. Kirtane 11:30 am - Discussion with Audience Q&A 11:35 am - Benefits and Pitfalls of CostEffectiveness Analyses David J. Cohen 11:45 am - Discussion with Audience Q&A 11:50 am - Final Words Donald Cutlip, Ajay J. Kirtane 12:00 pm - Adjourn Deep Dive: Stroke Prevention Therapies 8:00 am-12:00 Room 135 pm 9:10 am - The Screening Process: A Painful But Essential Step David A. Cox Session I. Stroke Demographics Moderators: William A. Gray, Mark Reisman Discussant: L. Nelson Hopkins 9:20 am - Informed Consent: Follow the Rules Kate Dalton 8:00 am - The Opportunity for Prevention: Mechanisms and Incidence of Cardiac and Atheroembolic Stroke L. Nelson Hopkins 9:30 am - Quality Control: Investigator’s Responsibilities Timothy D. Henry 9:40 am - How to Handle Monitoring Visits and Audits Roxana Mehran 9:50 am - Discussion with Audience Q&A Session II. Clinical Trial Interpretation: Pitfalls and Practical Lessons Moderators: Donald Cutlip, Ajay J. Kirtane Discussants: Somjot S. Brar, Davide Capodanno, David J. Cohen, Sanjay Kaul, Mitchell W. Krucoff, Helen Parise, John L. Petersen, Stuart J. Pocock, John A. Spertus 10:20 am - Randomized Trials vs. Observational Studies: Both Are Good, Both Can Be Bad Roxana Mehran 10:30 am - Discussion with Audience Q&A 10:35 am - Practicalities and Misapplications of Composite Endpoints in Clinical Trials Stuart J. Pocock 10:45 am - Discussion with Audience Q&A 10:50 am - Importance of Adequately Powered Studies in Clinical Medicine: Case Studies Sanjay Kaul 11:00 am - Discussion with Audience Q&A 11:05 am - Noninferiority Exposed: Uses and Abuses Donald Cutlip 9:20 am - Not All Asymptomatic Lesions Are the Same: Objective Measures of the Higher-Risk Lesion Issam D. Moussa 9:28 am - Medical Therapy: Do the Data Support Not Intervening in the Severe Asymptomatic Carotid Lesion? Peter A. Schneider 9:36 am - Surgery for the Asymptomatic Carotid Stenosis: Randomized Trial Evidence-Based Medicine Roger M. Greenhalgh 9:44 am - Carotid Stenting and the Asymptomatic Patient: Can It Be Advocated for Prevention of Stroke? James P. Zidar 9:52 am - Surgery vs. Carotid Stenting for the Symptomatic Patient: Why Is There Such Discrepant Data on Safety? William A. Gray 10:02 am - Intracranial Atherosclerosis: Evaluation, Therapeutic Options, and Outcomes Philip M. Meyers 10:12 am - Discussion with Audience Q&A Session II. Atrial Fibrillation Moderators: William A. Gray, Mark Reisman Discussants: Michael D. Ezekowitz, L. Nelson Hopkins, Vivek Y. Reddy, Peter N. Ruygrok Session IV. Patent Foramen Ovale Moderators: Zahid Amin, Eustaquio Maria Onorato Discussants: Stephen J.D. Brecker, Paul H. Kramer, Mark Reisman, Jonathan M. Tobis 8:10 am - The Brave New World of Antithrombotic Therapy for Stroke Prevention in Atrial Fibrillation Michael D. Ezekowitz 10:27 am - Screening for the PFO-Related Stroke: Is There a Best Method? Paul H. Kramer 8:25 am - Surgical Approaches to Preventing Stroke in Atrial Fibrillation: Rhythm Ablation and Appendage Exclusion A. Marc Gillinov 10:35 am - A Critical Appraisal of CLOSURE I and Status Report on RESPECT and REDUCE Jonathan M. Tobis 8:40 am - Electrophysiologic Ablation for Atrial Fibrillation: Methods and Efficacy Vivek Y. Reddy 10:45 am - Does the Device Matter? The Landscape of Current and Future PFO Closure Devices Mark Reisman 8:52 am - Transcatheter Atrial Appendage Occlusion: From the Watchman Proof of Concept to Emerging Next Generation Devices Peter N. Ruygrok 10:55 am - Is Migraine a Separate Consideration When Assessing the Patient with PFO and Stroke? Stephen J.D. Brecker 9:05 am - Discussion with Audience Q&A Session III. Carotid and Intracranial Therapy Moderators: Michael R. Jaff, Robert D. Safian Discussants: William A. Gray, Roger M. Greenhalgh, Philip M. Meyers, Issam D. Moussa, Peter A. Schneider, James P. Zidar - N o v e m b e r 9 , 2 0 11 8:25 am - Improving Efficiencies with the IRB, Budgets, and Contracts Lauren T. Privitera 11:15 am - Discussion with Audience Q&A Wednesday 8:05 am - How to Establish Clinical Research in Your Hospital: The Essential First Steps Bruce R. Brodie T r a n s c at h e t e r Cardiovascular Therapeutics 11:05 am - Discussion with Audience Q&A Session V. The Great Stroke Debates Moderators: Peter C. Block, John M. Lasala Discussants: Joseph P. Carrozza Jr, Christopher B. Granger, David J. Hildick-Smith, Peter Sick Progress in Anticoagulant Therapy Will Obsolete Left Atrial Appendage Occlusion 11:20 am - Pro! Christopher B. Granger www.tctconference.com 105 Wednesday, November 9 11:28 am - Con! Peter Sick 11:36 am - Discussion and Vote First-Time PFO Strokes Should Not Be Closed 11:40 am - Pro! Joseph P. Carrozza Jr 11:48 am - Con! David J. Hildick-Smith 11:56 am - Discussion and Vote 12:00 pm - Adjourn Innovative Surgical Techniques and Technologies This session is not CE accredited for nurses. 8:00 am-12:00 pm Room 133 Co-sponsored by the American Association for Thoracic Surgery Session I. Coronary Artery Disease Moderators: Johannes Bonatti, John D. Puskas Discussant: Husam H. Balkhy 8:00 am - When Is Off-Pump the Right Choice? John D. Puskas 9:35 am - Transapical Closure of Paravalvular Leaks Mathew Williams 9:45 am - Discussion with Audience Q&A Session III. Aneurysmal Disease Moderators: W. Randolph Chitwood Jr, Allan Stewart Discussant: Grayson H. Wheatley 9:55 am - Composite Bioroot: Is Anyone Too Young for a Tissue Valve? Allan Stewart 10:05 am - Hybrid Therapy for Aneurysms Grayson H. Wheatley 10:15 am - Discussion with Audience Q&A Session IV. Atrial Fibrillation Moderators: Michael Argenziano, Timothy J. Gardner Discussants: Husam H. Balkhy, A. Marc Gillinov 10:20 am - Is There an Indication for Stand-Alone Surgical AF Treatment—And Why Are We Not Seeing These Patients? Michael Argenziano 10:30 am - Hybrid Surgical and Percutaneous AF Ablation Husam H. Balkhy 8:10 am - Robotic Approaches Really Work! Johannes Bonatti 10:40 am - Concomitant Surgical Ablation: What Is the Right Procedure? A. Marc Gillinov 8:20 am - Anastamotic Connectors: Is There a Role? Husam H. Balkhy 10:50 am - The Left Atrial Appendage: A Surgical Target? A. Marc Gillinov 8:30 am - Discussion with Audience Q&A 11:00 am - Discussion with Audience Q&A Session II. Valvular Heart Disease Moderators: Neil E. Moat, Mathew Williams Discussants: Michael Argenziano, Thierry A. Folliguet, James S. Gammie, A. Marc Gillinov, Francesco Maisano, Vinod H. Thourani Session V. Heart Failure Moderators: William E. Cohn, Ulrich P. Jorde Discussants: Robert E. Michler, Amit Patel 8:35 am - Sutureless Surgical Aortic Valve Replacement Thierry A. Folliguet 8:45 am - Is There a Role for the Apicoaortic Conduit in the TAVR Era? James S. Gammie 8:55 am - Apical Closure Devices Vinod H. Thourani 9:05 am - Surgery After Failed MitraClip Procedures: A Critical Appraisal Michael Argenziano 11:10 am - LVADs of Tomorrow William E. Cohn 11:20 am - Destination Therapy: Will This Ever Be a Reality? Ulrich P. Jorde 11:30 am - The Future of CABG and SVR in CHF After STICH Robert E. Michler 11:40 am - Stem Cell Therapy: The Role of Surgery and Surgeons Amit Patel 11:50 am - Discussion with Audience Q&A 12:00 pm - Adjourn 9:15 am - Robotic Mitral Repair: A Step Forward? A. Marc Gillinov 9:25 am - Transapical Mitral Repair with Artificial Chords Francesco Maisano 106 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s International Debating Chamber: Interventional Cardiology on Trial Sponsored by the British Cardiovascular Intervention Society 8:00 am-11:55 Room 104 am 8:00 am - Introduction, Session Outline, and Goals Mark A. de Belder Conflagration I. Early PCI for a Patient with Stable CAD Moderators: Mark A. de Belder, William E. Boden Discussants: Steven R. Bailey, Adrian P. Banning, Daniel S. Berman, William E. Boden, Bernard De Bruyne, Cindy L. Grines, Philip M. Urban, David O. Williams 8:03 am - Session and Participant Introduction Mark A. de Belder, William E. Boden 8:06 am - Case Presentation Introduction: A Patient with New Onset Moderate Angina Undergoes Early Angiography and PCI Keith G. Oldroyd Motion: Medical Treatment Is the First-Line Treatment for Patients with Stable Angina with Revascularization Reserved for Uncontrolled Symptoms 8:09 am - For: The Evidence Is Clear: To Do Otherwise Is Potentially Harmful and Costly! Judith S. Hochman 8:19 am - Against: We’ve Moved on: Ischemia/ FFR Guided Revascularization Will Achieve the Best Outcomes for Patients! Dean J. Kereiakes 8:29 am - Jury Deliberations (Issue in General and Patient Specific) 8:49 am - Panel Discussion and Audience Vote 8:52 am - Case Presentation Conclusion: Procedural and Late Patient Outcomes Keith G. Oldroyd 8:55 am - Final Judicial Sentence and Take-Home Messages Mark A. de Belder, William E. Boden Conflagration II. Duration of Dual Antiplatelet Therapy for Patients Undergoing PCI with DES Moderators: Anthony H. Gershlick, C. Michael Gibson Discussants: Alison L. Calver, Nick Curzen, Laura Mauri, Matthew T. Roe, Manel Sabate, Gary L. Schaer, Bonnie H. Weiner, Azfar G. Zaman 9:00 am - Session and Participant Introduction Frederick Feit, Anthony H. Gershlick The World’s Premier Interventional Experience TCT2011 Motion: The Guidelines Are Wrong: We Do Not Need Prolonged Dual Antiplatelet Therapy for Most Patients Undergoing PCI with DES 9:16 am - Against: The Longer and More Potent DAPT the Better! Daniel I. Simon 9:26 am - Jury Deliberations (Issue in General and Patient Specific) 9:46 am - Panel and Audience Vote 9:49 am - Case Presentation Conclusion: Procedural and Late Patient Outcomes Patricia J. Best 9:52 am - Final Judicial Sentence and Take-Home Messages Anthony H. Gershlick, C. Michael Gibson Conflagration III. TAVR in the Not So High-Risk Surgical Candidate Moderators: Lars G. Svensson, Martyn R. Thomas Discussants: Yaron Almagor, Adrian P. Banning, Daniel J. Blackman, Mark W. Connolly, Michael J. Mullen, Uday Trivedi, Hugo Vanermen, Olaf Wendler 9:57 am - Session and Participant Introduction Lars G. Svensson, Martyn R. Thomas 10:00 am - Case Presentation Introduction: A Moderate-Risk Aortic Stenosis Patient Refuses Surgical Aortic Valve Replacement Roberto Corti Motion: With Appropriate Informed Consent, TAVR Should Be Considered for ModerateRisk Patients Who Prefer the Lesser Invasive Approach 10:03 am - For: The Outcomes Are Good—Let the Patient Have the Say! Brian Whisenant 10:13 am - Against: Has Civilization Lost Its Mind?! Robert A. Guyton 10:25 am - Jury Deliberations (Issue in General and Patient Specific) 10:45 am - Panel and Audience Vote 10:48 am - Case Presentation Conclusion: Procedural and Late Patient Outcomes Roberto Corti Conflagration IV. Arterial Access and Pharmacological Approach to PCI Moderators: Warren J. Cantor, Nick Curzen Discussants: Robert J. Applegate, Bagrat Alekyan, Sripal Bangalore, Daniel J. Blackman, Ronald Caputo, Anthony H. Gershlick, Luis A. Guzman, Martial Hamon, James Nolan, Marco V. Wainstein, Bernhard Witzenbichler 10:56 am - Session and Participant Introduction Warren J. Cantor, Nick Curzen 10:59 am - Case Presentation: A Patient with STEMI Undergoes Radial Access with Heparin Anticoagulation Only (No Bivalirudin or GP IIb/IIIa Inhibitor) and with Thrombus Aspiration Goran K. Olivecrona Motion: Radial Access and Thrombus Aspiration Are the New Standard of Care for Primary PCI in STEMI—The Type of Anticoagulation Is Less Important 11:02 am - For: Radial Access Prevents Most Bleeding, and Thrombus Aspiration Is More Effective Than Any Antiplatelet Agent! Sanjit S. Jolly 11:12 am - Against: Bivalirudin Has the Highest Level of Evidence on Both Continents, and Is the Only Proven Default Therapy! Frederick Feit 11:22 am - Jury Deliberations (Issue in General and Patient Specific) 11:42 am - Panel and Audience Vote 11:45 am - Case Presentation Conclusion: Procedural and Patient Outcomes Goran K. Olivecrona 11:48 am - Final Judicial Sentence and Take-Home Messages Warren J. Cantor, Nick Curzen 12:00 pm - Adjourn Presentation Theaters 12:15 pm -1:15 pm Please see page 155 for the Presentation Theater schedule. Lunchtime Activities Hot Topics ACC Fellows Session I. Advanced Training in Valvular Heart Disease 12:15 pm-1:50 pm Room 131 - N o v e m b e r 9 , 2 0 11 9:06 am - For: To Prescribe DAPT in Most Patients for More Than Six Months Is Cruel and Unusual Punishment! Marco Valgimigli 10:51 am - Final Judicial Sentence and Take-Home Messages Lars G. Svensson, Martyn R. Thomas Wednesday 9:03 am - Case Presentation Introduction: A Patient Undergoes Elective PCI with DES and Is Prescribed DAPT Indefinitely Patricia J. Best T r a n s c at h e t e r Cardiovascular Therapeutics Advanced Training in Valvular Heart Disease Moderators: Vasilis Babaliaros, Wesley R. Pedersen Discussants: Raoul Bonan, Mathew Williams 12:15 pm - Essentials of Mitral Valvuloplasty Wesley R. Pedersen 12:30 pm - Essentials of Aortic Valvuloplasty Samin K. Sharma 12:45 pm - Essentials of Percutaneous Mitral Valve Repair Raoul Bonan 1:00 pm - Essentials of Transcatheter Aortic Valve Replacement Vasilis Babaliaros 1:15 pm - Working with Cardiothoracic Surgeons Mathew Williams 1:30 pm - Discussion with Audience Q&A 1:45 pm - Adjourn Career Development for the “New” Interventionalist This session is not CE accredited for nurses. 12:15 pm-1:45 pm Room 130 Moderator: Manish A. Parikh Discussants: Navin K. Kapur, Sahil A. Parikh, Matthew J. Price, Michael J. Rinaldi, Uma S. Valeti, James P. Zidar 12:15 pm - Introduction Manish A. Parikh 12:20 pm - Getting Started in an Academic Group Practice: What to Do and What Not to Do James P. Zidar 12:30 pm - Getting Started in a University Practice: What to Do and What Not to Do Navin K. Kapur 12:40 pm - Building a Niche: How to Transition from the “New” Interventionalist to the “Expert” Group Michael J. Rinaldi www.tctconference.com 107 Wednesday, November 9 12:50 pm - Tips, Tricks, and Rookie Mistakes When Starting as an Interventionalist: Discussion with Audience Q&A Session III. Preparing for the Future: The TAVR Example Moderator: Harry R. Phillips 12:55 pm - The BARI-2D Trial: Is the Revascularization Glass Really Empty? Frederick Feit 1:00 pm - Balancing Multiple Skills: Building a Portfolio Uma S. Valeti 1:22 pm - Hybrid Rooms, Logistics, Interdepartmental Cooperation: Incremental Steps or the All-in Approach? William F. Fearon 1:03 pm - Which Diabetic Patients with Multivessel and Left Main Disease Should Undergo PCI in 2011? Donald Cutlip 1:29 pm - Discussion with Audience Q&A 1:11 pm - Which Diabetic Patients with Multivessel and Left Main Disease Should Undergo CABG in 2011? Joseph F. Sabik 1:10 pm - Practical Implications of Health Care Reform Randel Richner 1:20 pm - Juggling Clinical Practice and Clinical Research Matthew J. Price 1:30 pm - Ten Things to Do in Your First Five Years to Grow Your Career Manish A. Parikh 1:40 pm - Discussion with Audience Q&A 1:50 pm - Adjourn Cath Lab Directors Roundtable: Managing the Present, Preparing for the Future 12:15 pm-1:45 pm Room 125 Moderator: Kishore J. Harjai Discussants: Simon R. Dixon, Stephen G. Ellis, Peter S. Fail, Cindy L. Grines, William W. O’Neill, Harry R. Phillips, David Jonathan Sahn, Ron Waksman, Bonnie H. Weiner 12:15 pm - Introduction and Session Goals Kishore J. Harjai Session I. PCI Appropriateness and Unnecessary Procedures Moderator: Cindy L. Grines 12:18 pm - The Issue and Implications: The Pandora’s Box of PCI Appropriateness Criteria William W. O’Neill 12:25 pm - The Challenges of Credentialing and Peer Review Stephen G. Ellis 12:32 pm - Discussion with Audience Q&A Session II. Resource Utilization and Metrics Moderator: Stephen G. Ellis 12:47 pm - Efficiency Metrics in the Cath Lab: Focus on Costs, Equipment Utilization, and On-Time Starts Peter S. Fail 12:52 pm - Cost vs. Quality in the Cath Lab: A Fork in the Road? Bonnie H. Weiner 12:57 pm - Integrating Clinical Research in a Busy Lab: Is it Worth it? Ron Waksman 1:02 pm - STEMI Metrics: The Pitfalls of Door-to-Balloon Time Kishore J. Harjai 1:42 pm - Closing Remarks Kishore J. Harjai 1:45 pm - Adjourn Diabetes and Cardiovascular Disease: New Therapeutic Approaches 12:15 pm-1:45 pm Room 124 New Therapeutic Approaches Moderators: Michael E. Farkouh, Frederick Feit 12:15 pm - Introduction and Session Goals Michael E. Farkouh 12:17 pm - Diabetes and Coronary Large/Small Vessel Arteriopathy: Truths and Myths Robert S. Schwartz 12:24 pm - Optimal Periprocedural and Chronic Medical Therapy in the Diabetic: Agents and Goals J. Dawn Abbott Case I. The Patient with Diabetes, Coronary Artery Disease, and Silent Ischemia: Medical Therapies and the Decision Whether to Revascularize Moderators: Michael E. Farkouh, Frederick Feit Discussants: Carlo Briguori, Donald Cutlip, Efrain Gaxiola, Margaret B. McEntegart 12:32 pm - Case Presentation Introduction: Patient Presentation and Diagnostic Testing (Pre-angiography) Kevin J. Beatt 12:35 pm - The Discussion: Optimizing Medical Therapy, Whether to Cath and Revascularize 12:43 pm - Case Presentation Conclusion: Management and Long-term Outcomes of This Patient Kevin J. Beatt 12:47 pm - General Discussion: Optimal Risk-Factor Management in Diabetic Patients, and Triggers for Noninvasive and Invasive Coronary Screening Moderators: Michael E. Farkouh, Frederick Feit Discussants: J. Dawn Abbott, Aaron D. Kugelmass, Norman E. Lepor, Margaret B. McEntegart, Robert S. Schwartz, Vankeepuran S. Srinivas 1:07 pm - Discussion with Audience Q&A 108 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 1:19 pm - Stent Selection in Diabetic Patients: Rationale and Design of the TUXEDO Trial Upendra Kaul Case II. PCI vs. CABG in the Patient with Diabetes Requiring Revascularization Moderators: Michael E. Farkouh, Frederick Feit Discussants: Donald Cutlip, A. Pieter Kappetein, Joseph F. Sabik 1:27 pm - Case Presentation Introduction: A Complex Diabetic and the Heart Team Discussion David H. Adams, Samin K. Sharma 1:30 pm - The Heart Team Discussion: How Would We Have Managed This Patient? 1:38 pm - Case Presentation Conclusion: The Revascularization Decision and Patient Outcomes David H. Adams, Samin K. Sharma 1:42 pm - Concluding Remarks Frederick Feit 1:45 pm - Adjourn Guidelines and Appropriateness Criteria Discussions: PCI in the United States and Europe 12:15 pm-1:45 pm Room 123 PCI in the United States and Europe Moderators: Kurt Huber, Glenn N. Levine, Manesh R. Patel Discussants: Eric R. Bates, Paul S. Chan, Timothy D. Henry, Michel R. Le May, Maurizio Menichelli, John D. Puskas, Erick Schampaert, Thomas D. Stuckey, David Taggart, Corrado Tamburino, Holger Thiele 12:15 pm - Highlights of the Latest US PCI and CABG Guidelines Glenn N. Levine 12:30 pm - Highlights of the Latest European PCI Guidelines (Including NSTEMI and STEMI) Kurt Huber The World’s Premier Interventional Experience TCT2011 1:00 pm - General Discussion OK, What Training Do I Need to Be a Focused Interventional . . . Expert? 1:15 pm - Valve Therapy Samir R. Kapadia 1:00 pm - Case 1: A Patient with Unprotected Left Main Coronary Artery Disease Corrado Tamburino 1:25 pm - Discussion 1:05 pm - Discussion: What Do the US/EU Guidelines and Appropriateness Criteria Say? Discussants: Michael Argenziano, Paul S. Chan, Kurt Huber, Erick Schampaert, David Taggart 1:40 pm - Discussion 1:15 pm - Case 2: A Patient with STEMI 60 Minutes from the Nearest Cath Lab Timothy D. Henry 12:15 pm-1:45 pm Room 132 Moderators: Todd J. Brinton, Paul Yock Discussants: Peter J. Fitzgerald, Howard M. Holstein, Ross A. Jaffe, Joshua Makower, James R. Shay 1:20 pm - Discussion: What Do the US/EU Guidelines and Appropriateness Criteria Say? Discussants: Eric R. Bates, Michel R. Le May, Maurizio Menichelli, Thomas D. Stuckey, Holger Thiele 1:30 pm - Discussion with Audience Q&A 1:45 pm - Adjourn Physician Training Requirements for the “Interventional Futurist” This session is not CE accredited for nurses. 12:15 pm-1:45 pm Room 102 Moderators: Doff B. McElhinney, Mark Reisman Discussants: Michael J. Davidson, Samir R. Kapadia, Michael J. Lim, Ganesh Manoharan, Jeffrey J. Popma, Krishna J. Rocha-Singh 12:15 pm - New Interventional (and Surgical) Skill Sets: Multifocal Access (Transseptal, Transapical, and Endovascular Plus Transvascular) and Implants (Clamshells, Plugs, Clips, and Valves) Mark Reisman 12:25 pm - Discussion 12:30 pm - Mastering New Imaging Modalities: Echo, CT, and Beyond Michael J. Lim 12:40 pm - Discussion OK: I’m a . . . and I Want to Become an “Interventional Futurist”: What’s Next? 12:45 pm - Fellow-in-Training Jeffrey J. Popma 12:50 pm - Practicing (Primarily) Coronary Interventionalist Ganesh Manoharan 1:30 pm - Hypertension Therapy Krishna J. Rocha-Singh 1:45 pm - Adjourn So You Think You Have a Great Idea? An Inventor’s Workshop Sponsored by Stanford Biodesign 12:15 pm - Introduction and Goals Paul Yock 12:18 pm - Secret Sauce: The Right Clinical Need Todd J. Brinton 12:28 pm - Discussion with Audience Q&A 12:32 pm - Assessing the Market (Without Hiring an MBA) Ross A. Jaffe 12:42 pm - Discussion with Audience Q&A 12:46 pm - IP 101: Is Your Device Patentable? James R. Shay 12:56 pm - Discussion with Audience Q&A 1:00 pm - The New Regulatory Logic for CE Mark and FDA Approval Howard M. Holstein 1:10 pm - Discussion with Audience Q&A 1:14 pm - Strategy Assessment: Is This a Product or a New Company? Joshua Makower 1:24 pm - Discussion with Audience Q&A 1:28 pm - Getting Real: Practical Next Steps Peter J. Fitzgerald 1:38 pm - Discussion with Audience Q&A 1:42 pm - Wrap-up Paul Yock 1:45 pm - Adjourn Special JACC Session: How to Write and Evaluate Medical Journal Articles 12:15 pm-1:45 pm Room 133 Moderators: Anthony N. DeMaria, Sotirios Tsimikas Discussant: David J. Moliterno 12:15 pm - How to Write Publishable Papers (with Examples of Dos and Don’ts) Anthony N. DeMaria 12:35 pm - Discussion with Audience Q&A 12:45 pm - How to Evaluate a Research Paper: What Constitutes a Good Review? Sotirios Tsimikas 1:05 pm - Discussion with Audience Q&A - N o v e m b e r 9 , 2 0 11 Applying the US and EU Guidelines and Appropriateness Criteria (from Revascularization Decisions to Pharmacotherapy) 12:55 pm - Practicing or In-Training Surgeon Michael J. Davidson Wednesday 12:45 pm - Highlights of the Appropriateness Use Criteria, and How to Apply Them in Daily Practice Manesh R. Patel T r a n s c at h e t e r Cardiovascular Therapeutics 1:15 pm - How to Enhance Your Paper Through Electronic Media David J. Moliterno 1:35 pm - Discussion with Audience Q&A 1:45 pm - Adjourn Learn the Technique Acute Stroke Intervention 12:15 pm-1:45 pm Room 112 Session I. Flash Lectures Moderators: L. Nelson Hopkins, Philip M. Meyers Discussants: Alex Abou-Chebl, Stephen R. Ramee 12:15 pm - Essential Anatomy for Stroke Intervention L. Nelson Hopkins 12:23 pm - Patient Selection: Clinical and Imaging Philip M. Meyers 12:31 pm - Current Technical Options for Successful Revascularization Stephen R. Ramee 12:39 pm - Complication Avoidance and Management Alex Abou-Chebl 12:47 pm - Roundtable Discussion: How to Train Non-Neurointerventionalists for Stroke Intervention Session II. Case Presentations Moderators: L. Nelson Hopkins, Philip M. Meyers Discussants: Alex Abou-Chebl, Stephen R. Ramee 12:55 pm - Successful Merci Stephen R. Ramee 1:05 pm - Successful Penumbra Alex Abou-Chebl 1:15 pm - Successful Stentriever (Solitaire) L. Nelson Hopkins www.tctconference.com 109 Wednesday, November 9 1:25 pm - Complication: Hemorrhage Post-Revascularization Philip M. Meyers 1:35 pm - Complication: Procedural Perforation L. Nelson Hopkins 1:45 pm - Adjourn Complex Congenital Intervention 12:15 pm-1:45 pm Room 120 Moderators: Ziyad M. Hijazi, John F. Rhodes Discussants: Elchanan Bruckheimer, Ralf J. Holzer, Eric Horlick, Frank F. Ing, Carlos Pedra 12:15 pm - Coarctation of the Aorta: Techniques for Stent Implantation Elchanan Bruckheimer 12:25 pm - Two Illustrative Cases of Coarctation Stent Placement: One Uncomplicated and One Complex Eric Horlick 12:40 pm - Discussion with Audience Q&A 12:45 pm - Coronary AV Fistulas: Treatment Techniques John F. Rhodes 12:55 pm - Two Illustrative Fistula Occlusion Cases: One Uncomplicated and One Complex Ziyad M. Hijazi 1:10 pm - Discussion with Audience Q&A 12:45 pm - A Case Series of DES In-Stent Restenosis (with Insights from Intracoronary Imaging) Fausto Feres 1:00 pm - A Case Series of Late DES Thrombosis (with Insights from Intracoronary Imaging) Fernando Alfonso 1:15 pm - A Case Series of Embolized Stents and Other Devices John S. Douglas Jr 1:30 pm - A Case Series of Vascular Complications: Radial and Femoral Robert J. Applegate 1:45 pm - Adjourn Day-to-Day Use of IVUS 12:15 pm-1:45 pm Room 121 Moderators: John McB. Hodgson, Clemens von Birgelen Discussants: Hector M. Garcia-Garcia, Gary S. Mintz 12:15 pm - Why We Need IVUS in the OCT Era Clemens von Birgelen 12:20 pm - How to Perform IVUS: Right and Wrong (Case Examples) John McB. Hodgson 12:40 pm - Lesion and Plaque Assessment with IVUS Techniques (Case Examples) Hector M. Garcia-Garcia 1:15 pm - Paravalvular Mitral Leaks: Indications for Treatment and Outcomes Zoltan G. Turi 1:00 pm - IVUS for Stent Optimization Including Bifurcation PCI (Case Examples) Brian Courtney 1:25 pm - Two Illustrative Cases: One Uncomplicated and One Complex Transapical LV Closure Thomas Walther 1:20 pm - Use of IVUS in the Recognition, Evaluation, and Management of PCI Complications (Case Examples) Clemens von Birgelen 1:40 pm - Discussion with Audience Q&A 1:40 pm - Take-Home Messages for Your Day-to-Day Work John McB. Hodgson 1:45 pm - Adjourn Coronary Complication Management (Part 1) 12:15 pm-1:45 pm Room 122 Moderators: Fernando Alfonso, Joseph P. Carrozza Jr Discussants: Robert J. Applegate, John S. Douglas Jr, Fausto Feres, Jose P.S. Henriques 12:15 pm - A Case Series of Coronary Perforations: Causes and Management Joseph P. Carrozza Jr 1:45 pm - Adjourn Left Main Intervention 12:15 pm-1:45 pm Room 111 Moderators: David J. Hildick-Smith, David E. Kandzari Session I. The Syntax Score 12:15 pm - How to Calculate the Syntax Score (Step by Step): It’s Not So Hard (with Case Examples) Philippe Genereux, Tullio Palmerini 12:30 pm - A Case Series of Refractory Intracoronary Thrombosis and No-Reflow Jose P.S. Henriques 110 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Session II. Management of the Distal Left Main Bifurcation Provisional Stenting with Crossover Is Usually Possible Discussants: Remo Albiero, Davide Capodanno, Nick Curzen, Bon-Kwon Koo 12:27 pm - Case 1: You Might Not Have Thought So in This Case Remo Albiero 12:33 pm - Case 2: You Might Not Have Thought So in This Case Davide Capodanno 12:39 pm - Case 3: Use of FFR to Avoid the Left Circumflex Entirely Bon-Kwon Koo 12:45 pm - Case 4: Use of IVUS to Simplify and Optimize Left Main PCI Nick Curzen The Planned Two-Stent Technique Discussants: Alaide Chieffo, Andrejs Erglis, Issam D. Moussa, Paul S. Teirstein 12:51 pm - Case 5: TAP/T: When to Choose and How to Do Paul S. Teirstein 12:57 pm - Case 6: Crush/Mini-Crush: When to Choose and How to Do Alaide Chieffo 1:03 pm - Case 7: Culotte: When to Choose and How to Do Andrejs Erglis 1:09 pm - Case 8: SKS/V/Y: When to Choose and How to Do Issam D. Moussa The Complex Distal Left Main Discussants: David E. Kandzari, Brij Maini, Keith G. Oldroyd, Teguh Santoso 1:15 pm - Case 9: LM Rotational Atherectomy Keith G. Oldroyd 1:21 pm - Case 10: Provisional vs. Prophylactic Hemodynamic Support Brij Maini 1:27 pm - Case 11: A Complex Distal Left Main Trifurcation (Three Important Branches) Antonio Colombo 1:33 pm - Case 12: The Restenotic Distal Left Main Segment David E. Kandzari 1:39 pm - Case 13: An Unforgettable Left Main PCI Complication Teguh Santoso 1:45 pm - Adjourn The World’s Premier Interventional Experience TCT2011 12:25 pm - Retrograde CTO PCI via Epicardial Collaterals; Primary Lesion Crossing with Wire Externalization Tony J. DeMartini 12:35 pm - Retrograde CTO PCI, Reverse CART with Wire Externalization Yaron Almagor 12:45 pm - Retrograde CTO PCI, IVUS-Guided Reverse CART with Wire Externalization Masahisa Yamane 12:55 pm - Retrograde CTO PCI, Traditional CART Technique Georgios Sianos 1:05 pm - Retrograde CTO PCI Requiring Wire Snaring for Externalization J. Aaron Grantham 1:05 pm - What Infrastructure Is Required for TAVR Complication Management? Todd M. Dewey 1:15 pm - Case 4: Aortic Insufficiency Post-TAVR Ulrich J. Gerckens 1:25 pm - Incidence, Mechanism, Treatment, and Consequences of Aortic Insufficiency Following TAVR Martyn R. Thomas 1:35 pm - Discussion with Audience Q&A 1:45 pm - Adjourn Transseptal Puncture: A How-to Guide 12:15 pm-1:48 pm Room 110 Moderators: Ted Feldman, Howard C. Herrmann Discussants: Peter C. Block, Eulogio J. Garcia, Paul H. Kramer, Karl-Heinz Kuck, Stefan Sack 12:15 pm - Basic Transseptal Technique and Indications Ted Feldman 12:27 pm - Discussion with Audience Q&A 1:15 pm - Retrograde CTO PCI: Complication Management (Collateral Perforation) Alfredo R. Galassi 12:30 pm - Case 1: Transseptal Puncture for Mitral Balloon Valvuloplasty with ICE Guidance Howard C. Herrmann 1:25 pm - Retrograde CTO PCI: Complication Management (Donor Vessel Thrombosis) Masahisa Yamane 12:40 pm - Case 2: Transseptal Puncture for MitraClip Repair 1 Ted Feldman 1:35 pm - Discussion with Audience Q&A 12:50 pm - Case 3: Transseptal Puncture for Pulmonary Vein Isolation Karl-Heinz Kuck 1:45 pm - Adjourn Transcatheter Aortic Valve Replacement 12:15 pm-1:45 pm Room 114 Moderators: Ulrich J. Gerckens, Martyn R. Thomas Discussants: Todd M. Dewey, Nicolo Piazza, Alec Vahanian 12:15 pm - Case 1: Vascular Access Site Complication Stephan Windecker 12:25 pm - Managing the Vascular Access Site in TAVR Ulrich J. Gerckens 12:35 pm - Case 2: Valve Embolization Nicolo Piazza 12:45 pm - Optimal Deployment Techniques in TAVR Alec Vahanian 1:00 pm - Imaging Guidance of Transseptal Puncture Location Howard C. Herrmann 1:12 pm - Discussion with Audience Q&A 1:15 pm - Case 4: Transseptal Puncture for MitraClip Repair 2 Peter C. Block 1:25 pm - Case 5: Transseptal Puncture for LAA Occlusion Stefan Sack 1:35 pm - Case 6: Transseptal Puncture for Paravalvular Leak Closure Eulogio J. Garcia 1:45 pm - Discussion with Audience Q&A 1:48 pm - Adjourn Afternoon Spotlight Sessions Aortic Endografts and Aneurysm Repair 2:00 pm-6:00 pm Room 134 Sponsored by the International Society of Endovascular Specialists Session I. Abdominal Aortic Aneurysm Repair (EVAR) Part 1 Moderators: Jacques Busquet, Christopher K. Zarins Discussants: Clifford J. Buckley, Frank J. Criado, Barry T. Katzen, Zvonimir Krajcer - N o v e m b e r 9 , 2 0 11 12:15 pm - Retrograde CTO PCI via Septal Collaterals; Primary Lesion Crossing with Wire Externalization Stéphane Rinfret 12:55 pm - Case 3: Hemodynamic Collapse During TAVR Martyn R. Thomas Wednesday Retrograde CTO Approach 12:15 pm-1:45 pm Room 113 Moderators: Carlo Di Mario, Craig A. Thompson Discussants: Yasushi Asakura, Tony J. DeMartini, Alfredo R. Galassi, Stéphane Rinfret, Georgios Sianos, Masahisa Yamane T r a n s c at h e t e r Cardiovascular Therapeutics 2:00 pm - EVAR Triumphs and Defeats: Critical Appraisal of the First 20 Years of the Endograft Era Frank J. Criado 2:10 pm - Are There Meaningful Differences Among the Current Aortic Endografts to Allow Customization to Specific Patient Anatomy? Clifford J. Buckley 2:20 pm - EVAR Devices: The Next Five Years Barry T. Katzen 2:30 pm - EVAR in the Future: Maximizing Device Durability to Minimize the Need for Surveillance and Reinterventions Christopher K. Zarins 2:40 pm - Role of EVAR in Treatment of Ruptured Aneurysms (RAAA): Current Status Christopher K. Zarins 2:50 pm - What Are the Impediments to Wider Adoption of Percutaneous EVAR? Zvonimir Krajcer 3:00 pm - Discussion with Audience Q&A Session II. Abdominal Aortic Aneurysm Repair (EVAR) Part 2 Moderators: Barry T. Katzen, Zvonimir Krajcer Discussants: Jacques Busquet, Tyrone J. Collins, Robert A. Lookstein, Kenneth Ouriel 3:15 pm - Optimal Management of the Small AAA: Can Early EVAR Be Justified? Kenneth Ouriel 3:25 pm - Indications for Intervention and Techniques for Treatment of Post-EVAR Endoleaks Barry T. Katzzen 3:35 pm - Contrast CTA Surveillance Is an Embattled and Increasingly Controversial Practice: What Are the Alternatives? Robert A. Lookstein www.tctconference.com 111 Wednesday, November 9 3:45 pm - Aneurysmal Common Iliac Arteries: Current Guidelines and Considerations for Extension into the External Iliac Jacques Busquet 3:55 pm - Renal Artery Stenosis and AAA: Optimal Timing of Treatment? Tyrone J. Collins 4:05 pm - Discussion with Audience Q&A Session III. Endograft Thoracic Aortic Repair (TEVAR) Moderators: Frank J. Criado, Rodney White Discussants: Timothy A.M. Chuter, W. Anthony Lee, Christoph A. Nienaber, Grayson H. Wheatley 4:20 pm - TEVAR Access Issues and Techniques Grayson H. Wheatley 4:30 pm - TEVAR Devices: State of the Art and Unmet Needs for 2011 Michael D. Dake 4:40 pm - Hybrid Solutions for TAA Involving the Aortic Arch Grayson H. Wheatley 4:50 pm - Does the Expansion of On-Label Indication for TEVAR Devices Matter? Frank J. Criado 5:00 pm - Branch-Vessel Strategies During Endovascular Treatment of Juxta-Visceral and Thoracoabdominal Aneurysms: Chimneys, Snorkels, and Periscopes W. Anthony Lee 5:10 pm - Update on Endovascular Repair of Acute Type B Aortic Dissection: Challenges and Possible Solutions Christoph A. Nienaber 5:20 pm - Branched Endograft Solutions for the Thoracoabdominal Aorta Timothy A.M. Chuter 5:30 pm - TEVAR Strategies for Treatment of Aortic Catastrophes: Emerging Evidence and Evolving Practices Rodney White 5:40 pm - Discussion with Audience Q&A 6:00 pm - Adjourn Integrating IVUS and FFR to Improve PCI Outcomes 2:00 pm-6:05 Room 104 pm Session I. The Basics and Intermediate Lesion Assessment Moderators: Bernard De Bruyne, John McB. Hodgson Discussants: William F. Fearon, Hector M. Garcia-Garcia, Morton J. Kern, Massoud A. Leesar, Gilles Rioufol 112 program · 2:00 pm - How I Use IVUS in the Cath Lab and Why: Basics, Practice, and Pitfalls Gilles Rioufol 2:15 pm - What Is Radiofrequency IVUS, and How Might It Be Used Clinically in the Cath Lab? Hector M. Garcia-Garcia 2:30 pm - How I Use FFR in the Cath Lab and Why: Basics, Practice, and Pitfalls Morton J. Kern 2:45 pm - FFR vs. IVUS for Assessment of LMCA and Non-LMCA Intermediate Lesions: Concordance, Discord, and How/When to Choose John McB. Hodgson 3:00 pm - FIRST: Correlation Between Radiofrequency Intravascular Ultrasound and Fractional Flow Reserve Parameters in Patients with Intermediate Coronary Stenoses Ron Waksman 3:10 pm - Discussion with Audience Q&A: Practicalities of IVUS and FFR and Their Cutoff Values Session II. Stump the IVUS/FFR Experts: Case Presentations Moderators: Morton J. Kern, Gary S. Mintz Discussants: Wacin Buddhari, Ricardo A. Costa, Jose de Ribamar Costa Jr, Michalis Hamilos, Sandeep Nathan, Huay Cheem Tan, Pim A.L. Tonino 3:25 pm - Case 1: IVUS and FFR in Intermediate Lesions Massoud A. Leesar 3:35 pm - Case 2: IVUS and FFR in Tandem Lesions William F. Fearon 3:45 pm - Case 3: One or More Artifacts Habib Samady 3:55 pm - Case 4: IVUS and FFR in Acute Coronary Syndromes Colin Berry Session III. IVUS/FFR Uses During PCI Moderators: Carlo Di Mario, Clemens von Birgelen Discussants: Lisette Okkels Jensen, Bon-Kwon Koo, Massoud A. Leesar, Matthew J. Price, Satoru Sumitsuji 4:05 pm - Use of IVUS During CTO Intervention (with Case Examples) Satoru Sumitsuji 4:15 pm - Use of IVUS and FFR in LMCA Interventions: When to Treat, How to Treat, Outcomes, and Clinical Decision-Making (with Case Examples) Matthew J. Price T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 4:25 pm - Role of IVUS After Stent Implantation: Optimization, Complications, and Predictors of Early and Late Events (with Case Examples) Massoud A. Leesar 4:35 pm - Role of FFR After Stent Implantation: Optimization, Sidebranch Assessment in LMCA and Non-LMCA Lesions, and More (with Case Examples) Bon-Kwon Koo 4:45 pm - Assessment of In-Stent Restenosis and Thrombosis (with Case Examples) Lisette Okkels Jensen 4:55 pm - Discussion with Audience Q&A Session IV. Clinical Strategies Moderators: William F. Fearon, Massoud A. Leesar Discussants: David J. Cohen, Bernard De Bruyne, Gary S. Mintz, Ajit Mullasari 5:10 pm - How I Integrate Selective Use of FFR and IVUS in the Cath Lab and Why Ajit Mullasari 5:20 pm - IVUS and IVUS/VH in Acute Coronary Syndromes: How to Interpret and Apply PROSPECT to Clinical Care Gary S. Mintz 5:30 pm - FFR in Multivessel Disease: A Practical Approach Based on FAME, SYNTAX, and COURAGE Bernard De Bruyne 5:40 pm - Cost-Effectiveness of PCI vs. CABG in Multivessel CAD: Implications of an FFR-Guided Strategy David J. Cohen 5:50 pm - Discussion with Audience Q&A 6:05 pm - Adjourn Next Generation Transcatheter Mitral Valve Therapies 2:00 pm-6:00 Room 135 pm Session I. The Challenges of CatheterBased Therapies for Mitral Regurgitation Moderators: Maurice Buchbinder, A. Marc Gillinov Discussants: Paul A. Grayburn, A. Pieter Kappetein, Robert J. Siegel, Renu Virmani 2:00 pm - A Noninvasive Cardiologist’s Perspective Paul A. Grayburn 2:08 pm - An Echocardiographer’s Perspective Robert J. Siegel 2:16 pm - A Surgeon’s Perspective A. Pieter Kappetein The World’s Premier Interventional Experience TCT2011 2:32 pm - Discussion with Audience Q&A 2:40 pm - Cardiac Dimensions Carrillon XE2: Foundational Results and Design Iteration Toward a Pivotal Clinical Trial Steven L. Goldberg 2:52 pm - Lessons from a Therapy on Hold: The Edwards Monarc (EVOLUTION I and II) Jan Harnek 3:00 pm - Lessons from a Therapy on Hold: Viacor PTMA Stefan Sack 3:08 pm - Coronary Sinus Annuloplasty Plus: Progress with Mitral Cerclage Robert J. Lederman 3:16 pm - Discussion with Audience Q&A Session III. Second Shot on Goal: Direct Annuloplasty Devices Moderators: Ted Feldman, Howard C. Herrmann Discussants: Maurice Buchbinder, Lutz Buellesfeld, Richard R. Heuser, Karl-Heinz Kuck, Francesco Maisano, Jason H. Rogers 3:26 pm - Guided Delivery Systems’ Accucinch: Device Description, Procedure, and Latest Patient Results Joachim Schofer 3:40 pm - Mitralign Bident: Current Device, Procedure, and Up-to-Date Clinical Outcomes Lutz Buellesfeld 4:52 pm - The Cardiosolutions Mitra-Spacer Anson Cheung 5:02 pm - The Valtech V-Chordal System Francesco Maisano 5:10 pm - Discussion with Audience Q&A Session V. Fourth Shot on Goal: Transcatheter Mitral Valve Replacement Moderators: Karl-Heinz Kuck, Joachim Schofer Discussants: Howard C. Herrmann, Georg Lutter, Michael J. Mack 5:20 pm - Progress with Transcatheter Mitral Valve Replacement 1: EndoValve Howard C. Herrmann 5:30 pm - Progress with Transcatheter Mitral Valve Replacement 2: CardiAQ Michael J. Mack 5:40 pm - Progress with Transcatheter Mitral Valve Replacement 3: The Lutter Bioprosthesis Georg Lutter 5:50 pm - Discussion with Audience Q&A 6:00 pm - Adjourn Optimizing Use of Today’s Antithrombotic and Antiplatelet Drugs in ACS, PCI, and Atrial Fibrillation 2:00 pm-6:05 Room 102 pm Debate: Point-of-Care Testing Should Dictate Selection of ADP Inhibitor 2:36 pm - Pro: Platelet Assays/Genotyping Are Useful! David Antoniucci 2:44 pm - Con: Relying on Platelet Assays/ Genotyping Is Misleading and Potentially Harmful! Sanjay Kaul 2:52 pm - Do Glycoprotein IIb/IIIa Inhibitors Still Have a Role in Selected Patients? Neal S. Kleiman 3:02 pm - Discussion with Audience Q&A Session II. Optimal Anticoagulant Therapy in ACS and PCI Moderators: Deepak L. Bhatt, E. Magnus Ohman Discussants: Kurt Huber, Stefan K. James, David F. Kong, Steven V. Manoukian, Julinda Mehilli, Shamir R. Mehta, Gregg W. Stone, George W. Vetrovec 3:17 pm - Patient Selection for Bivalirudin: In Whom Should It Be Required vs. Preferred vs. May Not Be Necessary? Gregg W. Stone 3:29 pm - Enoxaparin: Safe and Cost-Effective for All ACS and PCI Patients! Stefan K. James 3:41 pm - Heparin Alone Is Still the Most Widely Used Antithrombin Regimen—and Rightly So! Julinda Mehilli 3:51 pm - Fondaparinux Has a Role in the Right Patient Shamir R. Mehta 4:01 pm - Discussion with Audience Q&A 4:02 pm - RF-Based Mitral Annuloplasty: QuantumCor Richard R. Heuser Session I. Optimal Antiplatelet Therapy in ACS and PCI Moderators: Dominick J. Angiolillo, David J. Moliterno Discussants: David Antoniucci, Germano Di Sciascio, Stefan K. James, Sanjay Kaul, Neal S. Kleiman, Shamir R. Mehta, Victor L. Serebruany, Sigmund Silber, Jurrien M. Ten Berg Session III. Chronic Anticoagulation in Patients with Atrial Fibrillation Moderators: Christopher B. Granger, Matthew T. Roe Discussants: Andrea Abizaid, Piera Capranzano, James H. Chesebro, Michael D. Ezekowitz, Stefan K. James, David F. Kong, Jeffrey J. Rade, Freek W.A. Verheugt 4:16 pm - The Valtech Catheter-Based Cardioband Francesco Maisano 2:00 pm - Role of Clopidogrel: Who Benefits, What Dose, and Pre- or Post-PCI? Shamir R. Mehta 4:28 pm - Micardia Dynoplasty: Progress Toward a Percutaneously Adjustable Mitral Ring Maurice Buchbinder 2:12 pm - Role of Prasugrel: Who Benefits, Who Doesn’t, and What Are the Risks and Contraindications? Sigmund Silber 4:16 pm - Patient Selection Considerations for the Oral Thrombin Inhibitor Dabigatran: Safety, Efficacy, Contraindications, and Caveats Michael D. Ezekowitz 4:30 pm - The Millepede Percutaneous Annuloplasty Ring Jason H. Rogers 2:24 pm - Role of Ticagrelor: Who Benefits, Who Doesn’t, and What Are the Risks and Contraindications? Stefan K. James 3:50 pm - HIFU-Based Mitral Annuloplasty: ReCor Karl-Heinz Kuck 4:40 pm - Discussion with Audience Q&A - N o v e m b e r 9 , 2 0 11 Session II. First Shot on Goal: Coronary Sinus Annuloplasty Devices Moderators: Jason H. Rogers, Alec Vahanian Discussants: Stephen G. Ellis, Steven L. Goldberg, Jan Harnek, Robert J. Lederman Session IV. Third Shot on Goal: Other Approaches Moderators: Olaf Franzen, James B. Hermiller Jr Discussants: Anson Cheung, Francesco Maisano Wednesday 2:24 pm - A Pathologist’s Perspective Renu Virmani T r a n s c at h e t e r Cardiovascular Therapeutics 4:26 pm - Patient Selection Considerations for the Oral Direct Factor Xa Inhibitor Rivaroxaban: Safety, Efficacy, Contraindications, and Caveats Freek W.A. Verheugt www.tctconference.com 113 Wednesday, November 9 4:36 pm - Patient Selection Considerations for the Oral Direct Factor Xa Inhibitor Apixaban: Safety, Efficacy, Contraindications, and Caveats Christopher B. Granger 4:46 pm - Perspectives on the “New” Anticoagulants for Nonvalvular Atrial Fibrillation: When Is Warfarin Acceptable and Cost-Effective? Matthew R. Reynolds 4:56 pm - Strategies for the Patient Requiring Aspirin, Clopidogrel, and Chronic Anticoagulation David F. Kong 5:06 pm - Discussion with Audience Q&A Session IV. Emerging Novel Therapies Moderators: C. Michael Gibson, Frans Van de Werf Discussants: Deepak L. Bhatt, Kirk N. Garratt, David J. Moliterno, Freek W.A. Verheugt, Pascal Vranckx 5:21 pm - The Clinical Potential for Intravenous ADP Receptor Blockers (and Lessons Learned to Date) Deepak L. Bhatt 5:36 pm - The Clinical Potential for PAR-1 Inhibitors (and Lessons Learned to Date) David J. Moliterno 5:51 pm - Discussion with Audience Q&A 6:05 pm - Adjourn Surgical, Interventional, and Hybrid Procedures (Part 2): Valvular and Structural Heart Disease This session is not CE accredited for nurses. 2:00 pm-6:00 Room 133 pm Session I. Transfemoral vs. Transapical Access for TAVR Moderators: Axel Linke, Thomas Walther Discussants: Gregory P. Fontana, Jan Kovac, Neil E. Moat, Mathew Williams 2:00 pm - Transapical Is the Preferred Approach—Even if Suitable for Transfemoral! Thomas Walther 2:08 pm - Transfemoral (Whenever Feasible) Is the Preferred Approach! Jan Kovac 114 2:32 pm - Discussion with Audience Q&A Session II. TAVR Potpourri Moderators: Nicolo Piazza, Mathew Williams Discussants: Anson Cheung, Eberhard Grube, Larry L. Wood 2:40 pm - Valve-in-Valve for Failed Bioprosthetic Valves Anson Cheung 2:50 pm - TAVR Trends in Europe and What We Might Expect in the United States (Post-Approval) Larry L. Wood 5:16 pm - Discussion with Audience Q&A Session V. Structural Heart Disease Moderators: Gregory P. Fontana, Samir R. Kapadia Discussants: Roger J. Laham, Michael J. Mullen 5:24 pm - PFO: When Is Surgical or Percutaneous Closure Indicated? Michael J. Mullen 3:00 pm - TAVR: Parade of Next Generation Devices Eberhard Grube 5:34 pm - Periventricular Closure of Septal Defects Samir R. Kapadia 3:10 pm - Discussion with Audience Q&A 5:44 pm - Surgical and Percutaneous Options to Close the Left Atrial Appendage: What Really Works? Roger J. Laham Session III. Transcatheter Mitral Valve Procedures Moderators: A. Marc Gillinov, Alfredo Trento Discussants: Michael J. Davidson, Scott Lim, Neil E. Moat, Joachim Schofer 3:18 pm - Multidisciplinary Approach to Mitral Valve Disease Neil E. Moat 3:28 pm - MitraClip: Trends in Europe Francesco Maisano 3:38 pm - Training Surgeons to Do the MitraClip Procedure Scott Lim 3:48 pm - Are Surgical Options Preserved After Transcatheter Mitral Valve Procedures? Michael J. Davidson 3:58 pm - Beyond MitraClip: Parade of Transcatheter Mitral Valve Devices Joachim Schofer 4:08 pm - Discussion with Audience Q&A Session IV. Valve Surgery Moderators: A. Marc Gillinov, Neil E. Moat Discussants: Michael Argenziano, Steven F. Bolling, W. Randolph Chitwood Jr, James S. Gammie, Lars G. Svensson 5:54 pm - Discussion with Audience Q&A 6:00 pm - Adjourn Special Twilight Sessions Clinical Cardiovascular Genetics and the Era of Personalized Medicine 6:00 pm-8:00 pm Room 120 Moderators: W. Craig Hooper, H. Robert Superko Discussants: Colin M. Barker, James H. Chesebro, Robert Roberts, John Sninsky, George Wells 6:00 pm - Tools for Genomics and Pathophysiological Targets for Personalized Medicine James H. Chesebro 6:10 pm - Discussion with Audience Q&A 4:16 pm - Minimally Invasive Mitral Repair: How I Do It A. Marc Gillinov 6:15 pm - Is Genetic Testing for Clopidogrel Hyporesponsiveness Ready for Prime Time? Colin M. Barker 4:26 pm - Artificial Chords: How I Do It Steven F. Bolling 6:25 pm - Discussion with Audience Q&A 4:36 pm - Aortic Valve Repair: How I Do It Lars G. Svensson 2:16 pm - If Transfemoral Is Not Available, Alternative Vascular Access Is Preferable to Transapical! Neil E. Moat 4:46 pm - Who Should Have a Mitral Valve Replacement—Even If the Valve Is Repairable? James S. Gammie 2:24 pm - Stop the Turf Battle: A Collaborative Heart Team Should Decide! (Case Examples) Mathew Williams 4:56 pm - The Tricuspid Valve: When Should It Be Repaired? W. Randolph Chitwood Jr program · 5:06 pm - Update on NIH-Sponsored Mitral Regurgitation Trials Michael Argenziano T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 6:30 pm - Use of Genetic Markers in Families with a History of Coronary Artery Disease H. Robert Superko 6:40 pm - Discussion with Audience Q&A 6:45 pm - 9p21: Risk Marker or Gene Dose Severity? Robert Roberts The World’s Premier Interventional Experience TCT2011 7:00 pm - BIOSOLVE I: A Prospective Study of a Paclitaxel-Eluting Bioabsorbable Magnesium Stent in Patients with Coronary Artery Disease Raimund A. Erbel 7:10 pm - Discussion with Audience Q&A 7:10 pm - Discussion with Audience Q&A 7:15 pm - Multi-SNP Analysis: Risk Prediction Better Than Framingham and ARIC? George Wells 7:15 pm - SeQuent Please World Wide: A Large-Scale Registry Study of a Paclitaxel-Coated Balloon in Native Coronary Artery Lesions Jochen Wöhrle 7:25 pm - Discussion with Audience Q&A 7:30 pm - Genetics of VTE Risk and Comorbidities W. Craig Hooper 7:40 pm - Discussion with Audience Q&A 7:45 pm - Discussion: Current and Future Directions of Genomic-Directed Personalized Medicine 8:00 pm - Adjourn Featured Clinical Research III. Drug-Eluting Stents, Drug-Coated Balloons, and PCI Pharmacology 6:00 pm-8:00 pm Room 124 Moderators: Dominick J. Angiolillo, Bruno Scheller Discussants: Jorge A. Belardi, Rafael Beyar, Kishore J. Harjai, Oscar A. Mendiz, Expedito E. Ribeiro, Francesco Saia, Tabassome Simon, Peter Wenaweser 6:00 pm - MOST: A Prospective, Multicenter, Case-Control-Matched Study Investigating the Causes of Stent Thrombosis Using Optical Coherence Tomography and Platelet Function Testing Guido Parodi 6:10 pm - Discussion with Audience Q&A 6:15 pm - A Prospective, Randomized Trial of Prasugrel vs. Double-Dose Clopidogrel in Patients with ST-Segment Elevation Myocardial Infarction and Clopidogrel Hyporesponsiveness Dimitrios Alexopoulos 6:25 pm - Discussion with Audience Q&A 6:30 pm - SPICE: A Prospective, Randomized Trial of Four Antacid Strategies in Patients Receiving Clopidogrel Jean-Pierre Dery 6:40 pm - Discussion with Audience Q&A 6:45 pm - ACCEL-BLEED: A Prospective Study Examining the Relationship Between Platelet Reactivity and Bleeding Events After Percutaneous Coronary Intervention Young-Hoon Jeong 7:25 pm - Discussion with Audience Q&A 7:30 pm - PEPPER FIM: A Prospective, Multicenter, Registry of a Paclitaxel-Coated Balloon for Treatment of Coronary Bare Metal or Drug-Eluting Stent Restenosis Christoph Hehrlein 7:40 pm - Discussion with Audience Q&A 7:45 pm - A Prospective, Multicenter Registry of a Paclitaxel-Coated Balloon for Treatment of Femoropopliteal Arterial Disease Antonio Micari Session III. TAVR Session: Success, Failures, and Tips and Tricks Moderator: Antonio Colombo Discussants: Jean-Claude Laborde, Martin B. Leon 7:15 pm - CoreValve from the Master Jean-Claude Laborde 7:30 pm - Sapien from the Master Martin B. Leon 7:45 pm - Discussion with Audience Q&A 8:00 pm - Adjourn Focus on India: Interactive Case Review and Panel Discussion 6:00 pm-8:00 pm Room 131 Moderators: Ajay J. Kirtane, Manish A. Parikh Discussants: Sirish M Hiremath, Sreenivas Arramraju Kumar, Ashwin Balachand Mehta, Keyur H. Parikh, Ashok Seth 6:00 pm - Introductions 7:55 pm - Discussion with Audience Q&A 6:05 pm - Case 1: Coronary Artery Disease Intervention Complication 8:00 pm - Adjourn 6:15 pm - Discussion with Audience Q&A Partnership Session: JIM at TCT 6:20 pm - Case 2: Complex Peripheral Arterial Disease Intervention 6:00 pm-8:00 Room 122 pm Session I. Drug-Coated Balloons: Should They Be Used for Coronary In-Stent Restenosis and Bifurcations? Moderator: Jean-Claude Laborde Discussants: Antonio Colombo, Juan F. Granada 6:00 pm - No, DES and PTCA Are Fine for Most: DCB Are Unlikely to Work and/or May Not Be Safe! Juan F. Granada 6:10 pm - Yes, I Challenge the Rationale to Add Extra Metal: In Some Conditions, “a Drug and a Balloon” Will Be Better! Antonio Colombo 6:20 pm - Discussion with Audience Q&A - N o v e m b e r 9 , 2 0 11 6:55 pm - Discussion with Audience Q&A 7:00 pm - Translation of Genomics into Clinical Care: Quality and Strength of Evidence for Clinical Practice Improvements in Advance of Guidelines John Sninsky Wednesday 6:55 pm - Discussion with Audience Q&A T r a n s c at h e t e r Cardiovascular Therapeutics 6:30 pm - Discussion with Audience Q&A 6:35 pm - Case 3: Peripheral Arterial Disease Intervention Complication 6:45 pm - Discussion with Audience Q&A 6:50 pm - Dinner Break Discussants: Vinay Bahl, Upendra Kaul, Pratap Kumar, Samuel K. Mathew 7:15 pm - Case 4: Complex Structural Heart Disease Intervention 7:25 pm - Discussion with Audience Q&A 7:30 pm - Case 5: Structural Heart Disease Intervention Complication 7:40 pm - Discussion with Audience Q&A 7:45 pm - Closing Remarks 8:00 pm - Adjourn Session II. Challenging PCI: Selected Case Reviews Moderator: Gregg W. Stone Commentators: Ted Feldman, Eulogio J. Garcia, Augusto D. Pichard 6:30 pm - Really Diffuse Disease Augusto D. Pichard 6:45 pm - A Really Tough Bifurcation Lesion Antonio Colombo 7:00 pm - Complex In-Stent Restenosis Carlo Di Mario www.tctconference.com 115 Wednesday, November 9 Korean Interventional Cardiology Summit 6:00 pm-8:00 pm Hilton San Francisco Golden Gate 1, Lobby Level 333 O’Farrell St, San Francisco, CA Moderators: Joo-Young Yang, Jung-Han Yoon Panelists: Jae-Keon Chae, Tae-Soo Kang, Young-Hoon Kim, Young-Youp Koh, Sung-Jin Oh, Woo-Jung Park, Eun-Seok Shin 6:00 pm - Welcome Address Joo-Young Yang 6:05 pm - EES vs. First Generation DES: Are There Any Differences? Evidence from Meta-analyses Kyung-Woo Park 6:30 pm - Discussion 6:40 pm - Audience Q&A 6:50 pm - Break Case Studies 7:00 pm - Case 1: Multivessel Treatment 7:05 pm - Discussion 7:10 pm - Case 2: Bifurcation Disease 7:15 pm - Discussion 7:20 pm - Case 3: Left Main Disease 7:25 pm - Discussion 7:30 pm - Case 4: Long Lesion Disease 7:35 pm - Discussion 7:40 pm - Case 5: Small Vessel Disease 7:45 pm - Discussion 7:50 pm - Closing Thoughts and Take-Home Messages Jung-Han Yoon 8:00 pm - Adjourn Special Circulation Journal Session: The Most Important Interventional Papers from the Last Year 6:00 pm-8:00 pm Room 121 Moderators: David P. Faxon, David O. Williams Discussants: J. Dawn Abbott, Theodore A. Bass, Jane A. Leopold 6:00 pm - Introduction David P. Faxon 6:02 pm - Evaluation of the Second Generation of a Bioresorbable Everolimus-Eluting Vascular Scaffold for Treatment of De Novo Coronary Artery Stenosis: Six-Month Clinical and Imaging Outcomes Patrick W. Serruys 6:12 pm - Discussion with Audience Q&A Moderator: Theodore A. Bass Discussants: J. Dawn Abbott, David P. Faxon, Jane A. Leopold, Patrick W. Serruys, David O. Williams 6:20 pm - Incidence and Predictors of Early and Late Mortality After Transcatheter Aortic Valve Implantation in 663 Patients with Severe Aortic Stenosis Corrado Tamburino 6:30 pm - Discussion with Audience Q&A Moderator: David P. Faxon Discussants: J. Dawn Abbott, Theodore A. Bass, Jane A. Leopold, Corrado Tamburino, David O. Williams 6:40 pm - Platelet Reactivity and Cardiovascular Outcomes After Percutaneous Coronary Intervention: A Time-Dependent Analysis of the Gauging Responsiveness with a VerifyNow P2Y12 Assay: Impact of Thrombosis and Safety (GRAVITAS) Trial Matthew J. Price 6:50 pm - Discussion with Audience Q&A Moderator: J. Dawn Abbott Discussants: Theodore A. Bass, Bernard De Bruyne, David P. Faxon, Jane A. Leopold, David O. Williams 7:00 pm - Difference in Tissue Characteristics Between Early and Very Late Restenosis After Bare Metal Stent Implantation: An Optical Coherence Tomography Study Maoto Habara 7:10 pm - Discussion with Audience Q&A Moderator: David O. Williams Lead Discussant: Jane A. Leopold Discussants: J. Dawn Abbott, Theodore A. Bass, David P. Faxon, Maoto Habara 116 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 7:20 pm - Simple or Complex Stenting for Bifurcation Coronary Lesions: A PatientLevel Pooled Analysis of the Nordic Bifurcation Study and the British Bifurcation Coronary Study David J. Hildick-Smith 7:30 pm - Discussion with Audience Q&A Moderator: J. Dawn Abbott Discussants: Theodore A. Bass, David P. Faxon, David J. Hildick-Smith, Jane A. Leopold, David O. Williams 7:40 pm - Validation of Intravascular Ultrasound-Derived Parameters with Fractional Flow Reserve for Assessment of Coronary Stenosis Severity Gary S. Mintz 7:50 pm - Discussion with Audience Q&A Moderator: Jane A. Leopold Discussants: J. Dawn Abbott, Theodore A. Bass, David P. Faxon, Gary S. Mintz, David O. Williams 7:58 pm - Concluding Remarks David O. Williams 8:00 pm - Adjourn Evening Programs 7:00 pm -10:00 pm Please see page 156 for the Evening Programs schedule. The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Wednesday Educational Activities - N o v e m b e r 9 , 2 0 11 C a r d i o va s C u l a r researCh F o u n d at i o n Save the Dates Save the dates for these upcoming meetings sponsored by the Cardiovascular Research Foundation. p-c-i Live with TCT Complex PCI: A Live Case Demonstration Course with Left Main, Bifurcation, and CTO Interventions Gi2 with TCT TCT Russia April 11-13, 2012 XIV Moscow International Course on Endovascular Therapies February 23-25, 2012 Fellows Course December 9, 2011 New York Marriott Marquis April 19-22, 2012 Mandarin Oriental Hotel New York, NY Loews Miami Hotel December 1-2, 2011 Munich, Germany Annual Pulse of the City Gala New York, NY CIT in Partnership with TCT São Paulo, Brazil Interventional Cardiology Moscow, Russia Transcatheter Valve Therapies (TVT) 2012 Miami, FL June 2-5, 2012 Conference on Cell Therapy March 15-18, 2012 Angioplasty Summit-TCTAP for Cardiovascular Disease Beijing, China April 25-28, 2012 January 26-27, 2012 Vivien and Seymour Milstein Family Heart Center NewYork-Presbyterian/Columbia University Medical Center Optimizing PCI Outcomes: Seoul, South Korea Evolving Paradigms TCT Mediterranean 2012 March 2012 May 4-5, 2012 ACC.12/i2 Summit The Grand Resort Chicago, IL New York, NY Limassol, Cyprus May 28-30, 2012 Westin Seattle Seattle, WA Transcatheter Cardiovascular Therapeutics (TCT) 2012 October 22-26, 2012 Miami Beach Convention Center Miami, FL ACC.11/i2 Summit with TCT March 24-27, 2012 Chicago, IL Visit us at the Partnership Pavilion on the first floor of Moscone North. C A R D I O VA S C U L A R R E S E A R C H F O U N D AT I O N passion for innovation w w w . t c t c o n f e r e na c e.com 117 P L E A S E J O I N U S F O R Honoring Elizabeth Nabel, MD Mehmet Oz, MD And Special Guests for Championing Women’s Heart Health F R I D AY, D E C E M B E R 9 , 2 0 11 M A N DA R I N O R I E N TA L · T I M E W A R N E R C E N T E R 8 0 C O L U M B U S C I R C L E · N E W YO R K , N Y Cocktails, Dinner, and Dancing For more information about the gala or the women’s heart health summit, please contact Irma Damhuis at 646-434-4690 or [email protected]. 118 final program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Major Halls Main Arena............................................................................................... 120 How to Treat Theater: Coronary Artery Disease....................................... 121 How to Treat Theater: Endovascular and Structural Heart Disease...........122 Challenging Case Multiplex Challenging Case Theater........................................................................ 123 International Society-Sponsored Case Theater.........................................123 Maintenance of Certification (MOC) Course........................... 124 Special Sessions FDA Town Hall Meeting.............................................................................125 Morning Spotlight Sessions From Clinical Trials Evidence to Clinical Practice: Unraveling the Issues............................................................................... 126 Next Generation Transcatheter Aortic Valve Therapies............................. 126 Optimizing Primary PCI for STEMI (Part 1): The Systems Approach........ 127 Tough Calls in the Cath Lab: Are You Up to the Challenge?......................127 Presentation Theaters..................................................................... 160 Lunchtime Sessions Hot Topics................................................................................................ 128 Thursday Breakfast Meetings........................................................................... 157 Learn the Technique..................................................................................129 Drug-Coated Balloons: Clinical Data and Applications............................ 132 Next Generation Optical Intravascular Imaging: OCT and NIR Spectroscopy..................................................................... 133 Partnership Session: Brazilian Society of Interventional Cardiology (SBHCI) and Gi2: Transcatheter Aortic Valve Replacement and Complex Coronary Intervention................................... 134 Partnership Session: p-c-i Live in Partnership with TCT: Practical Aspects of Coronary, Valvular, and Electrophysiologic Interventions........ 134 san francisco, ca Special Twilight Sessions · Optimizing Primary PCI for STEMI (Part 2): Drugs, Devices, and Technique.................................................................133 the Moscone Center Deep Dive: Interventional Hypertension................................................... 131 November 10, 2011 Afternoon Spotlight Sessions Practicalities and Pitfalls of Platelet Function Testing.............................. 135 TCT Mediterranean...................................................................................135 Evening Programs.............................................................................. 161 www.tctconference.com 119 Thursday, November 10 Breakfast Meetings 7:00 am -8:00 am Please see page 157 for the Breakfast Meetings schedule. Plenary Session XII. TCT 2011 Inspirational Address and the TCT 2011 Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award Moderator: Gregg W. Stone Main Arena 8:00 am-6:00 pm Esplanade Ballroom Plenary Session X. Live Cases IV Live Case Moderator: Gregg W. Stone Live Case Co-Moderator: Horst Sievert Live Case Discussants: Elchanan Bruckheimer, David J. Cohen, Dariusz Dudek, Raimund A. Erbel, Chaim S. Lotan, Daniel J. McCormick, Gary S. Mintz, Robert D. Safian, Alec Vahanian, Brian Whisenant, Alan C. Yeung 8:00 am - Mayo Clinic Rochester, MN 8:45 am - Cardiovascular Centre, ZNA Middelheim Antwerp, Belgium Plenary Session XI. Adjunctive Pharmacology Considerations Moderators: Dominick J. Angiolillo, Dean J. Kereiakes Discussants: Deepak L. Bhatt, Laurent Bonello, James H. Chesebro, Dmitriy N. Feldman, C. Michael Gibson, Michelle O’Donoghue, Dirk Sibbing, Daniel I. Simon TCT Interventional Corner III. The Clinical Utility of Platelet Resistance and Genetic Testing 9:30 am - Selective but Important Value! Matthew J. Price 9:40 am - Research-Only Tool! Jean-François Tanguay 9:50 am - Discussion and Rebuttal 10:00 am - Synthesis Ajay J. Kirtane 10:05 am - Spotlight Lecture: Evidence-Based Pharmacotherapy Recommendations for PCI, NSTEMI, and STEMI: The Forest and the Trees Gregg W. Stone 10:45 am - TCT 2011 Inspirational Address: A Story of Despair, Hope, and Recovery in Japan Shigeru Saito 11:00 am - TCT 2011 Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award Award Presenter: Gregg W. Stone Award Finalists: Masaki Awata, Davide Capodanno, Thomas T. Tsai, Robert W. Yeh Plenary Session XIII. Late Breaking Clinical Trials and First Report Investigations II Focus on Transcatheter Aortic Valve Replacement Moderator: Jean-Claude Laborde Discussants: David J. Cohen, A. Pieter Kappetein, Martin B. Leon, Raj Makkar, Ian T. Meredith, Robert E. Michler, Neil E. Moat, William W. O’Neill, Jeffrey J. Popma, Matthew R. Reynolds, Martyn R. Thomas, Leif Thuesen 11:15 am - PARTNER Cohort B Two-Year: A Prospective, Randomized Trial of Transcatheter Aortic Valve Replacement vs. Standard Therapy in Patients with Inoperable Aortic Stenosis Raj Makkar 11:25 am - PARTNER Cohort A QOL: Qualityof-Life Analysis from a Prospective, Randomized Trial of Transcatheter Aortic Valve Replacement vs. Surgical Aortic Valve Replacement in High-Surgical-Risk Patients with Aortic Stenosis David J. Cohen 10:20 am - Spotlight Lecture: Novel Adjunctive PCI/ACS Pharmacologic Strategies and Agents: Have We Reached a Biologic Plateau? Harvey D. White 10:35 am - Discussion 120 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 11:33 am - PARTNER Cohort A CE: Cost-Effectiveness Analysis from a Prospective, Randomized Trial of Transcatheter Aortic Valve Replacement vs. Surgical Aortic Valve Replacement in High-Surgical-Risk Patients with Aortic Stenosis Matthew R. Reynolds 11:41 am - STACCATO: A Prospective, Randomized Trial of Transapical Transcatheter Aortic Valve Replacement vs. Surgical Aortic Valve Replacement in Low-Surgical-Risk Elderly Patients with Aortic Stenosis Leif Thuesen 11:51 am - Roundtable Discussion: Strengths, Limitations, and Implications of These Studies Focus on Primary PCI in STEMI Moderator: Eric R. Bates Discussants: John A. Bittl, Bruce R. Brodie, Frederick Feit, Martial Hamon, Sanjit S. Jolly, Ajay J. Kirtane, Harry R. Phillips, Enrico Romagnoli, Richard Smalling, Pieter R. Stella 12:15 pm - RIFLE STEACS: A Prospective, Randomized Trial of Radial vs. Femoral Vascular Access in Patients with ST-Segment Elevation Myocardial Infarction Enrico Romagnoli 12:25 pm - MUSTELA: A Prospective, Randomized Trial of Thrombectomy vs. No Thrombectomy in Patients with ST-Segment Elevation Myocardial Infarction and Thrombus-Rich Lesions Anna Sonia Petronio 12:35 pm - DEB-AMI: A Prospective, Randomized Trial of Paclitaxel-Coated Balloons plus Bare Metal Stents vs. PaclitaxelEluting Stents vs. Bare Metal Stents Alone in Patients with ST-Segment Elevation Myocardial Infarction Pieter R. Stella The World’s Premier Interventional Experience TCT2011 Live Case Moderator: Gregg W. Stone Live Case Co-Moderator: Bernard De Bruyne Live Case Discussants: Maurice Buchbinder, Ted Feldman, Howard C. Herrmann, David J. Hildick-Smith, Thomas A. Ischinger, Allen Jeremias, Dean J. Kereiakes, Sameer Mehta, John F. Rhodes, Joachim Schofer, Gerhard C. Schuler 1:00 pm - NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY 1:45 pm - Scripps Green Hospital La Jolla, CA Plenary Session XV. Clinical Trials: The Cornerstone of Evidence-Based Medicine Moderators: Patrick W. Serruys, Gregg W. Stone Discussants: Donald Cutlip, Dean J. Kereiakes, Michael J. Mack, Roxana Mehran, Helen Parise, Sunil V. Rao, Freek W.A. Verheugt, Pascal Vranckx, Stephan Windecker TCT Interventional Corner IV. Clinical Trial Design and Interpretation 2:30 pm - Randomized Trials Remain the Gold Standard! Gregg W. Stone 2:40 pm - Registries Are an Invaluable and Indispensable Tool! Ralph G. Brindis 2:50 pm - Discussion and Rebuttal 3:00 pm - Synthesis Peter Juni 3:05 pm - Spotlight Lecture: Common Sense Interpretation of Increasingly Sophisticated Statistics: Recent Case Study Examples Stuart J. Pocock 3:20 pm - Discussion Plenary Session XVI. Live Cases VI Live Case Moderator: Martin B. Leon Live Case Co-Moderator: Liliana R. Grinfeld Live Case Discussants: John D. Carroll, Charles J. Davidson, Larry S. Dean, Olaf Franzen, Eulogio J. Garcia, Anthony H. Gershlick, Steven L. Goldberg, Joshua M. Hare, Sigmund Silber, Daniel I. Simon, Rod H. Stables 4:15 pm - Scripps Green Hospital La Jolla, CA Plenary Session XVII. Structural Heart Disease Controversies Moderators: Michael J. Mullen, Jonathan M. Tobis Discussants: Stephen J.D. Brecker, Howard C. Herrmann, Eric Horlick, Stamatios Lerakis, Brad I. Munt, Ramon Quesada, Peter Sick, David E. Thaler, Brian Whisenant TCT Interventional Hot Topic III. PFO Closure for Stroke Prevention and Migraine Treatment 5:00 pm - The Clinical Needs (and Data) Are Compelling! John D. Carroll 5:10 pm - Evidence for Efficacy Is Sorely Lacking! Thomas G. Brott 5:20 pm - Discussion and Rebuttal TCT Interventional Hot Topic IV. Left Atrial Appendage Closure for Stroke Prevention 5:30 pm - Spotlight Lecture: Comprehensive Update on LAA Closure: Rationale, Indications, Clinical Trials (Completed and Ongoing), and Technologies Vivek Y. Reddy 5:45 pm - Discussion 6:00 pm - Adjourn How to Treat Theater: Coronary Artery Disease 8:00 am-6:00 Hall D pm Complex and Unusual Cases I Moderator: George D. Dangas Co-Moderator: Richard A. Schatz 8:00 am - Drivers of Revascularization in Stable Coronary Artery Disease: A Balanced Approach John A. Spertus 8:15 am - Revascularization Guidance in Patients with Diabetes Mellitus Ajay J. Kirtane Live Cases: Complex and Unusual Cases I Live Case Moderator: George D. Dangas Live Case Co-Moderator: Richard A. Schatz Live Case Discussants: Steven L. Almany, John A. Ambrose, Christoph A. Kaiser, Henning Kelbaek, Karel T. Koch, Karl-Heinz Kuck, Norman E. Lepor, Giora Weisz, Peter Wenaweser 8:30 am - Scripps Green Hospital La Jolla, CA 9:15 am - Mayo Clinic Rochester, MN 10:00 am - Discussion: What Have We Learned from These Cases? - N o v e m b e r 1 0 , 2 0 11 Plenary Session XIV. Live Cases V 3:30 pm - Swedish Health Services Seattle, WA Thursday 12:45 pm - Roundtable Discussion: Strengths, Limitations, and Implications of These Studies T r a n s c at h e t e r Cardiovascular Therapeutics Multivessel Disease I Moderator: Maurice Buchbinder Co-Moderator: Erick Schampaert 10:15 am - Next Generation Drug-Eluting Stents Today and Tomorrow: Evolution or Revolution? Stephan Windecker 10:30 am - How to Use FFR in Clinical Practice: From Basic to Advanced Bernard De Bruyne Live Cases: Multivessel Disease I Live Case Moderator: Maurice Buchbinder Live Case Co-Moderator: Erick Schampaert Live Case Discussants: Sripal Bangalore, Giulio Guagliumi, Yaling Han, Michael A. Kutcher, Detlef G. Mathey, Michael Mooney, Giuseppe M. Sangiorgi, Pim A.L. Tonino, Haichang Wang 10:45 am - Cardiovascular Centre ZNA Middelheim Antwerp, Belgium 11:30 am - Scripps Green Hospital La Jolla, CA 12:15 pm - Discussion: What Have We Learned from These Cases? 12:30 pm - Break Complex and Unusual Cases II Moderator: Jeffrey J. Popma Co-Moderator: Morton J. Kern 1:30 pm - Optimal Therapies in STEMI: Timing Issues, Pharmacotherapy, Stents, and More Bruce R. Brodie 1:45 pm - Optimal Therapies in NSTEMI: Timing Issues, Pharmacotherapy, Stents, and More Frans Van de Werf www.tctconference.com 121 Thursday, November 10 Live Cases: Complex and Unusual Cases II Live Case Moderator: Jeffrey J. Popma Live Case Co-Moderator: Morton J. Kern Live Case Discussants: Chales E. Chan, Valerian Fernandes, Bon-Kwon Koo, James R. Margolis, Jack L. Martin, Samuel K. Mathew, Miodrag C. Ostojic, Abhiram Prasad, Frederic S. Rensic 2:00 pm - Asan Medical Center Seoul, South Korea 2:45 pm - First Affiliated Hospital of Nanjing Medical University Beijing, China 3:30 pm - Discussion: What Have We Learned from These Cases? Multivessel Disease II Moderator: James B. Hermiller Jr Co-Moderator: Patrick L. Whitlow 3:45 pm - How Can PCI Outcomes in Multivessel Disease Be Improved? Jeffrey J. Popma 4:00 pm - Dual Antiplatelet Therapy Conundrums: Loading, Duration, Agents, and Point-of-Care Testing Dean J. Kereiakes Live Cases: Multivessel Disease II Live Case Moderator: James B. Hermiller Jr Live Case Co-Moderator: Patrick L. Whitlow Live Case Discussants: David Antoniucci, Kevin J. Beatt, Yoon Sin Chong, Marco A. Costa, Aaron D. Kugelmass, Harry R. Phillips, Jorge F. Saucedo, Sotirios Tsimikas, Yongjian Wu 4:15 pm - Asan Medical Center Seoul, South Korea 5:00 pm - First Affiliated Hospital of Nanjing Medical University Beijing, China 5:45 pm - Discussion: What Have We Learned from These Cases? 6:00 pm - Adjourn How to Treat Theater: Endovascular and Structural HEart Disease 8:00 am-6:00 Hall D pm Carotid and Neurovascular Intervention I Moderator: Peter A. Schneider Co-Moderator: Sumaira Macdonald 8:00 am - Carotid Artery Stenting and Endarterectomy: Individualized Patient Decision-Making Jay S. Yadav 8:15 am - Identifying the At-Risk Patient with Asymptomatic Critical Carotid Stenosis: A Neurology Perspective Wade S. Smith Live Cases: Carotid and Neurovascular I Live Case Moderator: Peter A. Schneider Live Case Co-Moderator: Sumaira Macdonald Live Case Discussants: Lee R. Guterman, R. Stefan Kiesz, D. Christopher Metzger, Issam D. Moussa, Antonios A. Polydorou, Amit Segev, Maarten J. Suttorp, Mark H. Wholey, Jose M. Wiley 8:30 am - Mirano General Hospital Mirano, Italy 9:15 am - NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY 10:00 am - Discussion: What Have We Learned from These Cases? Carotid and Neurovascular Intervention II Moderator: Jay S. Yadav Co-Moderator: Roger M. Greenhalgh 10:15 am - Differentiating Between Proximal and Distal Embolic Protection Devices: Patient Selection and Outcomes Sumaira Macdonald 10:30 am - What Are the Optimal Design Attributes for a Carotid Stent? Review of the Current Options and Future Directions Peter A. Schneider Live Cases: Carotid and Neurovascular II Live Case Moderator: Jay S. Yadav Live Case Co-Moderator: Roger M. Greenhalgh Live Case Discussants: J. Michael Bacharach, Enrique Criado, Peter S. Fail, Zvonimir Krajcer, Thosaphol Limpijankit, Flavio L. Ribichini, Peter A. Schneider, Eugenio Stabile, Adam Witkowski 10:45 am - Mirano General Hospital Mirano, Italy 11:30 am - NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY 12:15 pm - Discussion: What Have We Learned from These Cases? 12:30 pm - Break Adult Congenital I Moderator: John M. Lasala Co-Moderator: Michael J. Mullen 1:30 pm - After CLOSURE I, When Should a PFO Be Closed in 2011? Paul H. Kramer 1:45 pm - Paravalvular Leaks: Device Options, Current Results, and Future Directions Eulogio J. Garcia Live Cases: Adult Congential I Live Case Moderator: Eric Horlick Live Case Co-Moderator: Michael J. Mullen Live Case Discussants: Zahid Amin, Nirat Beohar, Ralf J. Holzer, John M. Lasala, Eustaquio Maria Onorato, Carlos Pedra, Ramon Quesada, Peter Sick, Thomas M. Tu 2:00 pm - Rush Center for Congenital and Structural Heart Disease at Rush University Medical Center Chicago, IL 2:45 pm - NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY 3:30 pm - Discussion: What Have We Learned from These Cases? Adult Congenital II Moderator: Elchanan Bruckheimer Co-Moderator: Frank F. Ing 3:45 pm - Left Atrial Appendage Closure: Devices and Results Peter N. Ruygrok 3:55 pm - The Large ASD: Device or Surgery? John F. Rhodes 4:05 pm - Current Experience with Transcatheter Pulmonic Valves Doff B. McElhinney 122 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 4:15 pm - Rush Center for Congenital and Structural Heart Disease at Rush University Medical Center Chicago, IL 5:00 pm - Swedish Health Services Seattle, WA 5:45 pm - Discussion: What Have We Learned from These Cases? 6:00 pm - Adjourn Challenging Case Multiplex Challenging Case Theater 9:00 am-5:00 Hall D pm Coronary Miscellaneous Moderators: Simon R. Dixon, Jonathan D. Marmur Discussants: Stephen P. Hoole, Takashi Kubo 9:00 am - Retrieval of an Entangled Diagnostic Catheter in the Femoral Artery: An Innovative Solution Ming Ming Sim 10:12 am - Retrograde Approach for a Left Main Ostial Occlusion Masaaki Okutsu 10:24 am - Left Main Coronary Artery Thrombus: Now What? 10:36 am - Bifurcation PCI Complicated by Coronary Rupture Jai-Wun Park 10:48 am - Early Stenosis of a Gortex Graft to the Left Main Coronary Artery with Rescue Angioplasty Luis Jhonathan Uribe Gonzalez Chronic Total Occlusion II Moderators: Mauro Carlino, S. Chiu Wong Discussants: Lei Ge, Talib Majwal 11:00 am - Rotablation for an Undilatable CTO Lesion Using the Rendezvous Technique Chao-Feng Liao 11:12 am - CTO Intervention with Minimum Use of Contrast Media Yoshiki Uehara 11:24 am - An Innovative Approach to Facilitate True Lumen Reentry from Subintimal Track in CTO Jon C. George 11:36 am - A Challenging Chronic Total Occlusion Vinny Ram 11:48 am - Left Main Chronic Total Occlusion with Retrograde Coronary Intervention Qi Zhang 12:00 pm - Break 9:12 am - Novel Treatment of an Emboli-Prone Coronary Atherosclerotic Aneurysm Corey Foster Transcatheter Valve Therapies: Aortic and Mitral Moderators: Jan Kovac, Stefan Sack Discussants: Flavio L. Ribichini, Amit Segev 9:24 am - Percutaneous Retrieval of an Entrapped and Transected Rotablator Burr Using a Snare Device Toru Mazaki 2:00 pm - TAVR in a Patient with Aortoiliac Endoprosthesis and Severely Tortuous Bilateral External Iliac Arteries Flavio L. Ribichini 9:36 am - Complex High Risk Rotational Atherectomy Supported by Extracorporeal Membrane Oxygenation Marco Magalhaes 2:12 pm - Transfemoral TAVR for Aortic Regurgitation Philipp Kahlert 9:48 am - Removal of a Fractured Angioplasty Guidewire Using Microcatheter and Microsnare Technique Min-Woong Kim Left Main and Bifurcation Moderators: Andrejs Erglis, Rod H. Stables Discussants: Mitsuyasu Terashima, Hiroyoshi Yokoi 10:00 am - Unprotected Left Main Bifurcation Restenosis Treated with Double Stenting Technique Marco V. Wainstein 2:24 pm - Urgent Bailout Reimplantation of the Sapien Aortic Valve: The Price of a Single Heart Beat Ran Kornowski 2:36 pm - Percutaneous Bioprosthesis Implantation in a Mitral Ring by Anterograde Approach Anna Sonia Petronio 2:48 pm - Modified Technique of Balloon Mitral Valvotomy for Severe Submitral Stenosis Arunkumar Panneerselvam Endovascular II Moderators: Tyrone J. Collins, Erich Minar Discussants: Thomas O. McNamara, Rahul S. Patel 3:00 pm - Unusual Vascular Access for Exclusion of a Large Traumatic Aorta Pseudoanuerysm Raul Rios-Mendez 3:12 pm - Transcatheter Aspiration for Superior Mesenteric and Celiac Arterial Thromboembolism Rie Sasaki 3:24 pm - Massive Pulmonary Embolism Treatment with Thrombolysis via DrugDelivery Catheter Michael Nuyles - N o v e m b e r 1 0 , 2 0 11 Live Case Moderator: Elchanan Bruckheimer Live Case Co-Moderator: Frank F. Ing Live Case Discussants: Hans R. Figulla, Vivek Gupta, Samir R. Kapadia, Kapildeo Lotun, Doff B. McElhinney, Srihari S. Naidu, Ali Oto, Peter N. Ruygrok, Steven J. Yakubov Thursday Live Cases: Adult Congential II T r a n s c at h e t e r Cardiovascular Therapeutics 3:36 pm - Unusual Case of Subclavian Steal Syndrome Kishore Sadanand 3:48 pm - Dual Injection to Facilitate Intervention of an Occluded Posterior Tibial Artery Prakash Krishnan Transcatheter Valve Therapies: Aortic Moderators: Nirat Beohar, Augusto D. Pichard Discussants: Mark Goldberger, Ghada W. Mikhail 4:00 pm - Repositioning of an Embolized Sapien XT Valve with an Inoue-Balloon Catheter via Left Subclavian Artery Access Hans R. Figulla 4:12 pm - TAVR: An Unusual Complication Dan Ioanes 4:24 pm - Repositioning of a CoreValve During TAVR Due to Low Implantation P. Patsalis 4:36 pm - Transcatheter Aortic Valve Implantation Following Thoracic Endovascular Repair with Vascular Surgery Bailout Uzoma Ibebuogu 4:48 pm - PCI in a TAVR Patient Massimo Mancone 5:00 pm - Adjourn International Society-Sponsored Case Theater 8:00 am-6:00 Hall D pm Cath Lab Nightmares Sponsored by the Brazilian Society of Interventional Cardiology Moderators: Mauricio R. Barbosa, Marcelo Queiroga Discussants: Jose Ary Boechat, Fabio S. Brito, Valter C. Lima, Carlos Pedra www.tctconference.com 123 Thursday, November 10 8:00 am - Case 1: Congenital - Intervention in an Early Failing Fontan Carlos Pedra Approach to Tough Bifurcation Lesions Sponsored by the Colegio Argentino de Cardioangiologia Intervencionista 3:30 pm - Case 3: Decisions, Decisions, Decisions: Not Your Everyday STEMI Case Jose P.S. Henriques 8:15 am - Case 2: TAVR - Accidental Repositioning of a Misplaced CoreValve Dimytri Siqueira Moderators: Oscar A. Mendiz, Ruben A. Piraino Discussants: Jorge A. Belardi, Liliana R. Grinfeld 3:45 pm - Case 4: High Thrombotic and Bilateral Occlusions in STEMI: Staging Approach with a Self-Expanding Stent Gillian A. Jessurun 8:30 am - Case 3: PCI - Preventing Distal Embolization During SVG Intervention Adriano Caixeta 8:45 am - Case 4: Intervention in a Calcified Lesion Paulo Caramori Decision-Making in STEMI Sponsored by the Cardiovascular Intervention Association of Thailand Moderator: Sarana Boonbaichaiyapruck Discussants: Wacin Buddhari, Kenneth Chin, Sameer Mehta, Huay Cheem Tan 11:00 am - Case 1: Provisional Stent and TAP Technique Daniel H. Berrocal 11:15 am - Case 2: Crush and Mini-Crush Technique Marcelo Halac 11:30 am - Case 3: Simultaneous Kissing Stents Gustavo Lev 11:45 am - Case 4: Culotte Technique Jorge H. Leguizamon 9:00 am - Case 1: STEMI of the Inferior Wall (Issues: Aspiration, Reperfusion Arrhythmias, Stent Decisions) Sarana Boonbaichaiyapruck 12:00 pm - Break 9:15 am - Case 2: STEMI of the Anterior Wall (Issues: Vascular Access and Anticoagulation) Sarana Boonbaichaiyapruck Moderators: Anthony Fung, Merril L. Knudtson Discussants: Vladimir Dzavik, Michel R. Le May, Erick Schampaert, Jean-François Tanguay 9:30 am - Case 3: STEMI of the Anterior Wall (Issues: Tandem Lesions, Direct Stenting, Imaging, and FFR) Sarana Boonbaichaiyapruck 9:45 am - Case 4: STEMI Due to Multivessel Stent Thrombosis with Shock (Issues: Thrombectomy, Multivessel Intervention, Possible CABG) Sarana Boonbaichaiyapruck SPANK the PCI Technique Sponsored by the Canadian Association of Interventional Cardiology 2:00 pm - Case 1: What’s Wrong with This CTO PCI Technique? Christopher E. Buller Lead Discussant: Jean-François Tanguay 2:15 pm - Case 2: What’s Wrong with This Bifurcation PCI Technique? Sam Radhakrishnan Lead Discussant: Vladimir Dzavik PCI Complications and Innovative Bailout Solutions Sponsored by the Cardiology Society of India 2:30 pm - Case 3: What’s Wrong with This Left Main PCI Technique? Eric A. Cohen Lead Discussant: Erick Schampaert Moderator: Samuel K. Mathew Discussants: Sameer Indravadan Dani, Ajit Menon, Ajit Mullasari, Dev B. Pahlajani 2:45 pm - Case 4: What’s Wrong with This STEMI PCI Technique? Albert W. Chan Lead Discussant: Michel R. Le May 10:00 am - Case 1: Severe CatheterInduced Dissection Samuel K. Mathew 10:15 am - Case 2: A Totally Unexpected Nightmare Upendra Kaul 10:30 am - Case 3: Stent Dislodgement in the Left Main Amal Kumar Banerjee 10:45 am - Case 4: Truly Undilatable Lesions Ashok Seth Complex Cases in ACS: Focus on Primary PCI Sponsored by the Dutch Society of Interventional Cardiology Moderators: Peter den Heijer, Jan J. Piek Discussants: Marek Grygier, Jose P.S. Henriques, Richard Smalling, Jochen Wöhrle 3:00 pm - Case 1: A Complex STEMI: When, What, and How Jeroen Vos 3:15 pm - Case 2: Primary PCI in STEMI with a Self-Deploying Stent Karel T. Koch 124 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Complex PCI: Managing Complications and Achieving Optimal Outcomes Sponsored by the Cardiac Society of Australia and New Zealand Moderator: Darren L. Walters Discussants: John A. Ormiston, Ajay Radheshyam Sinhal, Stephen G. Worthley 4:00 pm - Case 1: Making the Simple Complex Robert J. Whitbourn 4:15 pm - Case 2: Difficulty Crossing the Lesion? Mark W.I. Webster 4:30 pm - Case 3: Atherectomy of the Left Main Trifurcation David W.M. Muller 4:45 pm - Case 4: Stent Thrombosis After Left Main Stem Simultaneous Kissing Stents Nigel Jepson AMI Intervention: Focus on the Left Main Coronary Artery Sponsored by the Czech Working Group of Interventional Cardiology of the Czech Society of Cardiology Moderator: Petr Kala Discussants: Viktor Kocka, Pavel Cervinka, Roman Stipal, Michael Zelizko 5:00 pm - Case 1: STEMI and Transradial PCI of the Left Main Coronary Artery Ivo Bernat 5:15 pm - Case 2: Acute Left Main Coronary Artery Occlusion Treated with PCI Martin Mates 5:30 pm - Case 3: Complex PCI in STEMI Post-CABG Josef Bis 5:45 pm - Case 4: Unusual Case of Primary PCI Miroslav Brtko 6:00 pm - Adjourn Maintenance of Certification (MOC) Course This session is not CE accredited for nurses. 8:00 am-2:00 Room 103 pm 8:00 am - Welcome and Introduction TBA The World’s Premier Interventional Experience TCT2011 10:00 am - Break 12:00 pm - Interventional Cardiology 2009 Update Module Review Moderator: Emmanouil S. Brilakis Discussants: Tayo A. Addo, Charles E. Chambers 2:00 pm - Adjourn Special Sessions FDA Town Hall Meeting 8:00 am-5:00 Room 102 pm Part I. Cardiovascular Medical Device Innovation: Barriers and Solutions Session I. Cardiovascular Device Innovation in the United States: Scope of the Problem: Regulatory, Industry, and Physician-Scientist Perspectives Moderators: Paul A. LaViolette, Paul Yock Discussants: Rick Anderson, Ralph G. Brindis, Keith D. Dawkins, Jo Carol Hiatt, Aaron V. Kaplan, Frank Litvack, Bray Patrick-Lake, Campbell Rogers, Sean Salmon, Daniel G. Schultz, Charles A. Simonton, John B. Simpson, Ron Waksman, Bram D. Zuckerman 8:00 am - Regulatory Science, Innovation and the Public Health: Our Leading Imperative Vicki Seyfert-Margolis 8:12 am - Medical Device Innovation: Balancing Risk with Speed to Market William H. Maisel 8:24 am - Costs Too High, Incentives Too Low: Has the United States Lost Its Leading Position in Innovation? Paul A. LaViolette 8:36 am - The Pace of US Innovation: A Venture Capital Perspective Peter J. Fitzgerald 8:48 am - Viewpoints from a “Humble” Physician-Inventor Julio C. Palmaz 9:45 am - Break Session II. Cardiovascular Device Innovation Solutions: Think Tank Approach Moderators: Mitchell W. Krucoff, John B. Simpson Discussant: Richard S. Stack 1:55 pm - Discussion with Audience Q&A Moderators: Aaron V. Kaplan, William W. O’Neill Session V. New DES Indications Underway: Left Main Coronary Artery Intervention 10:00 am - Restoring an Ecosystem in Crisis: A Series of Suggestions Mitchell W. Krucoff Moderators: A. Pieter Kappetein, Mitchell W. Krucoff Discussants: Keith D. Dawkins, James B. Hermiller Jr, Jeffrey B. Jump, John D. Puskas 10:15 am - Possible Premarket vs. Postmarket Concepts and Solutions Andrew Farb 2:10 pm - Critical Trial Design: Lessons Learned for a Left Main Stent Study Martin B. Leon 10:30 am - Parallel Review: Alignment Between Federal Agencies Jyme H. Schafer 2:15 pm - FDA Talking Points Ashley B. Boam 10:45 am - The 510(k) Process Redesign 1: Modification or Reboot? William Vodra 11:00 am - The 510(k) Process Redesign 2: Modification or Reboot? William H. Maisel 11:15 am - Discussion with Audience Q&A 12:00 pm - Break Part II. Interventional Hot Topics Session III. Catheter-Based Treatment for Hypertension Moderators: Roxana Mehran, Robert S. Schwartz Discussants: Michael A. Kutcher, Semih Oktay, Horst Sievert, Christian M. Spaulding 1:00 pm - FDA Perspectives Kenneth J. Cavanaugh Jr 1:05 pm - Industry Perspectives 1 Martin T. Rothman 1:10 pm - Industry Perspectives 2 Keith D. Dawkins 1:15 pm - Physician-Scientist Perspectives Deepak L. Bhatt 1:20 pm - Discussion with Audience Q&A Session IV. AMI Therapies Moderators: Roxana Mehran, William W. O’Neill Discussants: C. Michael Gibson, Gonzague Issenmann, Kevin Larkin 1:35 pm - FDA Perspectives 1 Andrew Farb 1:40 pm - FDA Perspectives 2 Catherine P. Wentz 1:45 pm - Industry Perspectives Keith D. Dawkins 1:50 pm - Physician-Scientist Perspectives Bernard J. Gersh - N o v e m b e r 1 0 , 2 0 11 10:15 am - Interventional Cardiology 2010 Update Module Review Moderators: Steven R. Bailey, Charles E. Chambers Discussants: Tayo A. Addo, Emmanouil S. Brilakis 9:00 am - Discussion with Audience Q&A Thursday 8:05 am - Interventional Cardiology 2011 Update Module Review Moderator: Emmanouil S. Brilakis Discussants: Tayo A. Addo, Robert T. Pyo T r a n s c at h e t e r Cardiovascular Therapeutics 2:20 pm - Industry Perspectives Charles A. Simonton 2:25 pm - Discussion with Audience Q&A Session VI. New DES Indications Underway: Bifurcations Moderators: Roxana Mehran, Terje K. Steigen Discussants: Isabelle Martin, David G. Rizik, Sean Salmon 2:40 pm - Critical Trial Design: Lessons Learned for a Bifurcation Stent Study Martin B. Leon 2:45 pm - FDA Talking Points Andrew Farb 2:50 pm - Industry Perspectives Aaron V. Kaplan 2:55 pm - Discussion with Audience Q&A Session VII. Addressing “Off-Label Use” Expansion: The CTO Example Moderators: Aaron V. Kaplan, Craig A. Thompson Discussants: Ashley B. Boam, Dennis Donohoe, Gary C. Johnson, David F. Kong, Chad Kugler, Charles A. Simonton, Bradley H. Strauss 3:10 pm - FDA Perspectives Ashley B. Boam 3:15 pm - Industry Perspectives Gary C. Johnson 3:20 pm - Physician-Scientist Perspectives Charles A. Simonton 3:25 pm - Discussion with Audience Q&A Session VIII. Next Generation DES (Including Bioabsorbable Scaffolds): Proving Safety and Efficacy Moderators: Ian T. Meredith, Gregg W. Stone Discussants: Dennis Donohoe, Mitchell W. Krucoff, Motasim Sirhan, Josiah N. Wilcox 3:40 pm - FDA Perspectives 1: Preclinical Duane S. Pinto www.tctconference.com 125 Thursday, November 10 3:45 pm - FDA Perspectives 2: Clinical Andrew Farb 3:50 pm - Industry Perspectives Charles A. Simonton 3:55 pm - Physician-Scientist Perspectives Gregg W. Stone 4:00 pm - Discussion with Audience Q&A Session IX: Left Atrial Appendage Occlusion Moderators: Aaron V. Kaplan, Vivek Y. Reddy Discussants: Steven L. Alman, Ashley B. Boam, Albert W. Chan, Saibal Kar, Pam Simons Part i. With Significant Clinical Data Panel III. TAVR in High-Risk Aortic Stenosis: The PARTNER Trial Moderator: Roxana Mehran Discussants: Bernard J. Gersh, Peter Juni, Sanjay Kaul, Laura Mauri, Helen Parise, Duane S. Pinto, Stuart J. Pocock, Craig R. Smith 8:00 am - Needs and Expectations for Future TAVR Systems Martin B. Leon 9:24 am - The Trial and the Issues Stuart J. Pocock 9:36 am - Discussion with Audience Q&A 4:30 pm - Industry Perspectives 2 Richard J. Linder Panel IV. Does Ticagrelor “Work” in North America? The PLATO Trial Moderator: Roxana Mehran Discussants: Bernard J. Gersh, Peter Juni, Sanjay Kaul, Laura Mauri, Helen Parise, Duane S. Pinto, Stuart J. Pocock, John A. Spertus 4:35 pm - Physician-Scientist Perspectives Ted Feldman 9:56 am - The Trial and the Issues David F. Kong 4:40 pm - Discussion with Audience Q&A 10:08 am - Discussion with Audience Q&A 4:20 pm - FDA Perspectives Heather L. Agler 4:25 pm - Industry Perspectives 1 Keith D. Dawkins 5:00 pm - Adjourn Morning Spotlight Sessions Panel V. The DAPT Conundrum Moderator: Roxana Mehran Discussants: Ashley B. Boam, Bernard J. Gersh, Peter Juni, Sanjay Kaul, Laura Mauri, Helen Parise, Duane S. Pinto, Stuart J. Pocock From Clinical Trials Evidence to Clinical Practice: Unraveling the Issues 10:28 am - The Trial and the Issues Laura Mauri 8:00 am-11:45 Room 133 Panel VI. The Great P Value Debate Moderator: Helen Parise Discussants: Somjot S. Brar, Sanjay Kaul, Ajay J. Kirtane, David F. Kong, Dean J. Kereiakes, Roxana Mehran pm Featured Lecture Moderator: Roxana Mehran 8:00 am - Interpreting Clinical Trial Evidence: Lost in Translation Sanjay Kaul Panel I. Routine Early Angioplasty After Fibrinolysis Moderator: Stuart J. Pocock Discussants: Mark Andrew Hlatky, Peter Juni, Sanjay Kaul, Roxana Mehran, Helen Parise, Stephan Windecker 8:20 am - The Trial and the Issues Peter Juni 8:32 am - Discussion with Audience Q&A Panel II. Left Main DES vs. CABG: The EXCEL Trial Moderator: Stuart J. Pocock Discussants: Mark Andrew Hlatky, Peter Juni, Sanjay Kaul, Roxana Mehran, Helen Parise, Stephan Windecker 8:52 am - The Trial and the Issues Helen Parise 126 9:04 am - Discussion with Audience Q&A program · 10:40 am - Discussion with Audience Q&A Debate: Alpha and the “Magical” P < 0.05 Threshold 11:00 am - P Values Are Important—and Significant! Stuart J. Pocock 11:12 am - Down with P Values! Peter Juni 11:24 am - Discussion with Audience Q&A 11:45 pm - Adjourn Next Generation Transcatheter Aortic Valve Therapies 8:00 am-12:00 Room 135 pm Session I. New and Novel Transcatheter Aortic Valve Systems Moderators: Lutz Buellesfeld, Martin B. Leon Discussants: Joerg Kempfert, Rudiger Lange, Ganesh Manoharan, Ian T. Meredith, Joachim Schofer, Hendrik Treede T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 8:10 am - Results from the Symetis Transapical TAVR System Joerg Kempfert 8:22 am - Results from the Jena Valve Transapical TAVR System Hendrik Treede 8:34 am - Results from the Ventor Embracer Transapical TAVR System Rudiger Lange 8:46 am - Results from the Direct Flow Transfemoral TAVR System Joachim Schofer 8:58 am - The LOTUS Valve and the REPRISE Clinical Trial Program Ian T. Meredith 9:10 am - Results from the St. Jude’s Medical Transfemoral TAVR System Ganesh Manoharan 9:22 am - Discussion with Audience Q&A Part ii. First-in-Human Use and Preclinical Concepts 9:45 am - Heart Leaflet Technology Gerhard C. Schuler 9:49 am - AngioScore Valvuloplasty System Gary Gershony 9:53 am - Valve Medical Martin B. Leon 9:57 am - Colibri Bernard R. Chevalier 10:01 am - InterValve Valvuloplasty System Wesley R. Pedersen 10:05 am - Discussion with Audience Q&A Session II. Cerebral Protection Devices Moderators: Joseph E. Bavaria, Samir R. Kapadia Discussants: Ulrich J. Gerckens, Christoph K. Naber, Pieter R. Stella 10:15 am - Confronting the TAVR Stroke Issue: Background, Reality, and Potential Impact of Cerebral Protection Samir R. Kapadia 10:25 am - Early Clinical Experiences Using the SHEF Deflector Pieter R. Stella 10:37 am - Early Clinical Experiences Using the Embrella Deflector Ulrich J. Gerckens 10:49 am - Early Clinical Experiences Using the Claret Cerebral Filter Christoph K. Naber The World’s Premier Interventional Experience TCT2011 11:15 am - The Landscape of Transarterial “Large Hole” Vascular Closure Devices Peter J. Fitzgerald 11:27 am - The Landscape of Transapical “Large Hole” Closure Devices Michael J. Mack 11:39 am - A Primer on the New Expandable Sheath Technologies Antonio Colombo 11:49 am - Discussion with Audience Q&A 12:00 pm - Adjourn Optimizing Primary PCI for STEMI (Part 1): The Systems Approach 8:00 am-12:00 Room 104 pm Session I. Timely Reperfusion Across STEMI Systems Moderators: William J. French, Bernard J. Gersh Discussants: Kenneth W. Baran, Eric R. Bates, Christian W. Hamm, Christian Juhl Terkelsen 8:00 am - Important New Benchmarks from the 2011 ACC/AHA STEMI Guidelines Eric R. Bates 8:10 am - Contrasting the European and Current ACC/AHA STEMI Guidelines Christian W. Hamm 8:20 am - System Delays and Mortality Christian Juhl Terkelsen 8:30 am - Bypassing the ER at the STEMI Center: Trading-Off Speed vs. False Activations Kenneth W. Baran 8:40 am - STEMI Networks: Potentials and Pitfalls Bernard J. Gersh 8:50 am - Discussion with Audience Q&A Session II. Adjunctive Pharmacology and Interventional Issues Moderators: Cindy L. Grines, Christian W. Hamm Discussants: Bruce R. Brodie, Warren J. Cantor, Stefan K. James, Sigmund Silber 9:05 am - Integrating Fibrinolysis into a Hospital Transfer System Warren J. Cantor 11:35 am - Expansion of Primary PCI in Europe: The Stent for Life Project Carlo Di Mario Debate: Use of More Potent ADP Receptor Antagonists 11:45 am - Discussion with Audience Q&A 9:25 am - STEMI Systems Should Encourage Prasugrel, Preferably Given Upstream! Sigmund Silber 9:35 am - STEMI Systems Should Encourage Ticagrelor, Preferably Given Upstream! Stefan K. James 9:45 am - Discussion with Audience Q&A Session III. Optimizing Appropriate Cath Lab Activation Moderators: Kishore J. Harjai, Henry H. Ting Discussants: William J. French, Christopher B. Granger, Timothy D. Henry, Ivan C. Rokos, Christian M. Spaulding 10:00 am - Appropriate Cath Lab Activation: Optimizing ECG Interpretation Ivan C. Rokos 10:10 am - Insights from the North Carolina Cath Lab Activation Registry (CLAR) Christopher B. Granger 10:20 am - Challenging ECG and Coronary Anatomy at 4 am William J. French Debate: Treatment of the Cardiac Arrest Patient 10:30 am - Hypothermia and Emergent Catheterization Is Only Indicated for Resuscitated Ventricular Tachycardia/Fibrillation! Christian M. Spaulding 10:40 am - Hypothermia and Emergent Catheterization Is Also Indicated for Resuscitated Pulseless Electrical Activity and Asystole! Timothy D. Henry 10:50 am - Discussion with Audience Q&A Session IV. Quality Improvement Strategies and Health Policy Issues for STEMI Systems Moderators: Alice K. Jacobs, Ivan C. Rokos Discussants: Carlo Di Mario, Laura Mauri, Henry H. Ting 11:05 am - ACTION Registry-GWTG and Quality Improvement in Mission: Lifeline Ivan C. Rokos 12:00 pm - Adjourn Tough Calls in the Cath Lab: Are You Up to the Challenge? 8:00 am-12:00 Room 134 pm Session I. Clarifying Hemodynamics Moderators: Morton J. Kern, Zoltan G. Turi Discussants: Blase A. Carabello, Walter Desmet, James A. Goldstein, Ali Oto, Paul Sorajja, Patrick L. Whitlow - N o v e m b e r 1 0 , 2 0 11 Session III. Vascular Closure Devices Moderators: Nicolas van Mieghem, Mathew Williams Discussants: Antonio Colombo, Peter J. Fitzgerald, Michael J. Mack 9:15 am - Pharmacoinvasive Strategies: When Are They Indicated? Bruce R. Brodie Thursday 11:01 am - Discussion with Audience Q&A T r a n s c at h e t e r Cardiovascular Therapeutics 8:00 am - A Patient with Moderate Aortic Stenosis and Poor LV Function: Is it Hemodynamically Severe or Not? Michael S. Lee 8:08 am - Discussion 8:15 am - A Patient with Severe Neck Distension and a Little Pericardial Fluid: What’s the Diagnosis? Thomas M. Tu 8:23 am - Discussion 8:30 am - A Patient with Pulmonary Hypertension: Is It Worth Assessing for Vasodilator Response? Irene M. Lang 8:38 am - Discussion 8:45 am - A Patient with Hypertrophic Cardiomypathy—or Not? Carey D. Kimmelstiel 8:53 am - Discussion Session II. Demystifying Structural Heart Disease Hemodynamics Moderators: Ted Feldman, Gerhard C. Schuler Discussants: Jeroen J. Bax, Larry S. Dean, Eulogio J. Garcia, Saibal Kar, Andrew D. Michaels, Martyn R. Thomas 9:00 am - What’s Wrong with This Prosthetic Valve? Stefan Sack 9:08 am - Discussion 9:15 am - Is This Percutaneous Mitral Valve Repair Going Well or Not? Francesco Maisano 9:23 am - Discussion 11:15 am - First Medical Contact-to-Balloon Times: Metrics, Caveats, and Incentives Henry H. Ting 9:30 am - Is This Percutaneous Aortic Valve Replacement Going Well or Not? Nicolo Piazza 11:25 am - Public Reporting of PCI Mortality: The Massachusetts Experience Laura Mauri 9:38 am - Discussion 9:45 am - Is This Cardiac Assist Device Improving Hemodynamics or Not? Srihari S. Naidu www.tctconference.com 127 Thursday, November 10 Session III. Angiographic Bewilderment (Part 1): Cardiac Angiography Moderators: Jeffrey J. Popma, Patrick L. Whitlow Discussants: Sorin J. Brener, Ecaterina Cristea, Ralf J. Holzer, Pedro A. Lemos, Bonnie H. Weiner, Brian Whisenant 10:00 am - Should I Close This Shunt? Lynn Peng 10:08 am - Discussion 10:15 am - How Exactly Is This (Anomaly) Supplying Blood to the Heart? Frederick Feit 10:23 am - Discussion 10:30 am - Where Is That Blood Going on the LV Gram (Aneurysm, Diverticulum, Fistular, Other)? Ricardo A. Costa 10:38 am - Discussion 10:45 am - What’s Wrong with This Aorta? Takao Ohki 10:53 am - Discussion Presentation Theaters 12:15 pm -1:15 pm Please see page 160 for the Presentation Theater schedule. Lunchtime Sessions Hot Topics ACC Fellows Session II. Advanced Training in Structural (Non-valve) Heart Disease 12:15 pm-1:45 pm Room 133 Moderators: Zahid Amin, Jonathan M. Tobis Discussants: Vivek Y. Reddy, Paul Sorajja 1:45 pm - Adjourn Chronic Kidney Disease and Contrast Nephropathy 12:15 pm-1:45 pm Room 130 Debates and Case Dilemmas Moderators: Antonio L. Bartorelli, Somjot S. Brar, Roxana Mehran Discussants: Steven R. Bailey, Otavio Berwanger, Carlo Briguori, Charles J. Davidson, Augusto D. Pichard, Daniel I. Simon 12:15 pm - A Patient with Chronic Kidney Disease Requiring Complex PCI and TAVR Antonio L. Bartorelli 12:15 pm - Essentials of PFO Closure Jonathan M. Tobis Debate I. N-Acetylcysteine: Effective or No Better than Placebo? 12:30 pm - Discussion with Audience Q&A 12:25 pm - Pro! Somjot S. Brar 12:35 pm - Essentials of ASD/VSD Closure Zahid Amin 12:50 pm - Discussion with Audience Q&A 12:30 pm - Con! Otavio Berwanger 12:35 pm - Discussion Session IV. Angiography Bewilderment (Part 2): Peripheral Angiography Moderators: Stephen R. Ramee, Thomas Zeller Discussants: Thomas A. Ischinger, R. Stefan Kiesz, Robert A. Lookstein, Daniel J. McCormick, Greg Mishkel, Raghotham R. Patlola 12:55 pm - Essentials of Paravalvular Leak Closure Paul Sorajja 11:00 am - A Patient with Carotid Stenosis Plus an Intracerebral Unknown Lee R. Guterman 1:30 pm - Discussion with Audience Q&A 12:50 pm - Discussion 1:35 pm - Open Q&A Session Debate III. Contrast Removal (Hemofiltration and Coronary Sinus Aspiration) 11:08 am - Discussion 11:15 am - A Patient with a Malfunctioning Dialysis Shunt John A. Bittl 11:23 am - Discussion 11:30 am - A Patient with Renal Artery Stenosis and a Renal Parenchymal Disorder Mehdi H. Shishehbor 11:38 am - Discussion 11:45 am - A Patient with Abdominal Pain, Anemia, and a Vascular Disorder Michael J. Rinaldi 11:53 am - Discussion 12:00 pm - Adjourn 1:10 pm - Discussion with Audience Q&A 1:15 pm - Essentials of Left Atrial Appendage Closure Peter Sick 1:45 pm - Adjourn ACC Practitioners Session: Innovations to Manage, Maintain, and Expand Your Clinical Practice 12:15 pm-1:45 pm Room 132 Moderators: George D. Dangas, E. Murat Tuzcu Discussants: Prakash Krishnan, Manish A. Parikh, Krishna J. Rocha-Singh 12:15 pm - Aortic Valve Interventions E. Murat Tuzcu 12:30 pm - Structural Heart Disease Interventions Ted Feldman 12:45 pm - Endovascular Interventions Prakash Krishnan 1:00 pm - Hypertension Initiatives Krishna J. Rocha-Singh 1:15 pm - Quality Control and Appropriateness Criteria Manish A. Parikh 128 1:30 pm - Discussion with Audience Q&A program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Debate II. Matched Hydration/Diuresis (RenalGuard System) 12:40 pm - Pro! Carlo Briguori 12:45 pm - Con! Daniel I. Simon 12:55 pm - Pro! Steven R. Bailey 1:00 pm - Con! Augusto D. Pichard 1:05 pm - Discussion Debate IV. Contrast-Type Matters and Sodium Bicarbonate Helps 1:10 pm - Pro! Somjot S. Brar 1:17 pm - Con! Charles J. Davidson 1:24 pm - Discussion 1:30 pm - Discussion with Audience Q&A 1:40 pm - The Final Word: Preventive Strategies That Work and Don’t Somjot S. Brar 1:45 pm - Adjourn The World’s Premier Interventional Experience TCT2011 STEMI and NSTEMI 12:15 pm - 2011 STEMI Guidelines: What’s New? Frederick Kushner 12:25 pm - Discussion with Audience Q&A 12:30 pm - 2011 Focused Update for NSTEMI/UAP John A. Ambrose 12:40 pm - Discussion with Audience Q&A 12:45 pm - Recommendations for the Management of the Resuscitated Cardiac Arrest Patient: Should PCI Be Performed Routinely? Margaret B. McEntegart 12:55 pm - Discussion with Audience Q&A 1:00 pm - Role of GP IIb/IIIa Inhibitor Therapy in the Era of Bivalirudin and DAPT David X. Zhao 1:10 pm - Discussion with Audience Q&A 1:15 pm - Indications in 2011 for (1) Fibrinolytic Therapy, and (2) Timing of Transfer After Fibrinolytic Therapy for STEMI Jacqueline E. Tamis-Holland 1:25 pm - Discussion with Audience Q&A 1:30 pm - Case Presentation: Clinical Decision-Making David O. Williams 1:45 pm - Adjourn Minimizing and Managing Cath Lab Complications 12:15 pm-1:45 pm Room 125 Moderators: Stephen Balter, Cindy L. Grines, D. Christopher Metzger Discussants: Robert J. Applegate, David A. Cox, Robert D. Safian 12:15 pm - Coronary Dissections (Including Guiding Catheter Complications) Robert J. Applegate 12:30 pm - Vascular Access Complications (Including Retroperitoneal Bleeds) Robert D. Safian 12:45 pm - Distal Embolization and No-Reflow Cindy L. Grines 1:00 pm - Perforations and Cardiac Tamponade David A. Cox 1:30 pm - Excessive Radiation Complications Stephen Balter 1:45 pm - Adjourn Optimizing Care for Women with Cardiovascular Disease 12:15 pm-1:45 pm Room 123 Moderators: Alexandra J. Lansky, Bonnie H. Weiner Discussants: J. Dawn Abbott, John A. McPherson, Eugenia Nikolsky, Anna Sonia Petronio, Jennifer A. Tremmel 12:15 pm - Facility Management: Developing a Multidisciplinary Procedural Venue (Hybrid or Conventional ORs/Cath Labs and Equipment/Inventory) Alan Lumsden 12:25 pm - Discussion 12:30 pm - Staffing Challenges: Integrating the “Team” (Interventionalists, Surgeons, Anesthesia, Echo, Techs, Nurses)—What a Mess! Sam Radhakrishnan 12:40 pm - Discussion How It’s Done in the “Real World”: Meet the Successful Models 12:15 pm - Introduction and Goals Alexandra J. Lansky 12:45 pm - St. Paul’s Hospital, Vancouver, Canada Sandra Lauck 12:20 pm - Coronary and Microvascular Disease in Women: Diagnostic Challenges and Prognosis Jennifer A. Tremmel 12:56 pm - NewYork-Presbyterian Hospital/ Columbia University Medical Center, New York, NY Marian C. Hawkey, Mathew Williams 12:30 pm - Coronary Fibromuscular Dysplasia: An Under-Recognized Cause of ACS in Women Christopher E. Buller 1:07 pm - University of Toronto, Toronto, Canada Eric Horlick 12:40 pm - Discussion with Audience Q&A 12:45 pm - Bleeding Complications in Women Undergoing Revascularization: Implications and Prevention Eugenia Nikolsky 12:55 pm - Discussion with Audience Q&A 1:00 pm - TAVI and Percutaneous Mitral Valve Therapy Outcomes in Women: The European Experience Anna Sonia Petronio 1:10 pm - Discussion with Audience Q&A 1:15 pm - Peripheral Vascular Disease in Women: Prevalence, Prognosis, and Therapies J. Dawn Abbott 1:25 pm - Discussion with Audience Q&A 1:30 pm - Case Presentation: A Woman with Challenging Heart Disease John A. McPherson 1:40 pm - Discussion with Audience Q&A 1:45 pm - Adjourn The Evolving Cath Lab: Facility and Staffing Considerations 12:15 pm-1:45 pm Room 131 Moderators: Ganesh Manoharan, Mathew Williams Discussants: Martin B. Leon, Sam Radhakrishnan - N o v e m b e r 1 0 , 2 0 11 Moderators: Alice K. Jacobs, Frederick Kushner, David O. Williams Discussants: John A. Ambrose, Margaret B. McEntegart, Jacqueline E. Tamis-Holland, David X. Zhao 1:15 pm - Peripheral and Structural Complication Smorgasbord D. Christopher Metzger Thursday Guideline Directions and Controversies: STEMI and NSTEMI 12:15 pm-1:45 pm Room 124 T r a n s c at h e t e r Cardiovascular Therapeutics 1:18 pm - Intermountain Medical Center, Salt Lake City, UT Brian Whisenant 1:30 pm - Sweeping Changes in the Dynamic Interventional Global Landscape Martin B. Leon 1:40 pm - Discussion 1:45 pm - Adjourn Learn the Technique Acute Infarct Angioplasty and Cardiogenic Shock 12:15 pm-1:45 pm Room 120 Moderators: Brij Maini, Thomas D. Stuckey, Bernhard Witzenbichler Discussants: Dariusz Dudek, Ran Kornowski, Roger J. Laham 12:15 pm - How to Perform Left Main PCI in STEMI (Two Cases) Bernhard Witzenbichler 12:30 pm - When and How to Use Aspiration and Thrombectomy Devices (Two Cases) Dariusz Dudek 12:45 pm - How to Perform PCI in Cardiogenic Shock (Two Cases) Thomas D. Stuckey 1:00 pm - When to Treat Multiple Vessels in Patients With and Without Shock (Two Cases) Ran Kornowski www.tctconference.com 129 Thursday, November 10 1:15 pm - When and How to Use Impella in STEMI (Two Cases) Brij Maini 1:30 pm - Unusual Complications of Hemodynamic Support Devices (Two Cases) Roger J. Laham 1:45 pm - Adjourn Alcohol Septal Ablation 12:15 pm-1:45 pm Room 110 Moderators: John S. Douglas Jr, Srihari S. Naidu Discussants: Ali E. Denktas, Michael A. Fifer, Christopher D. Nielsen, Ulrich Sigwart 12:15 pm - Choosing the Patient: Symptoms, Anatomy, and Hemodynamics Srihari S. Naidu 12:25 pm - Tools of the Trade: Selecting Guides, Wires, Balloons, and Alcohol Dose John S. Douglas Jr 12:35 pm - Myocardial Contrast Echocardiography: How to Perform It and What to Look for Christopher D. Nielsen 12:45 pm - Multiple Septals: How to Choose the Right Ones Case Presenter: Ulrich Sigwart 12:55 pm - Discussion 1:00 pm - Borderline Anatomy: Deciding Whether to Proceed Case Presenter: Michael A. Fifer 1:10 pm - Discussion 1:15 pm - Procedural Complications Case Presenter: Ali E. Denktas 1:35 pm - Access for Treating Peripheral Vascular Disease: Complications and Their Management Richard R. Heuser 1:00 pm - Case Review 2: How to Perform the Mini-Crush Technique in a Complex Bifurcation Ioannis Iakovou 1:45 pm - Adjourn 1:15 pm - Case Review 3: How to Perform the Culotte Technique in a Complex Bifurcation Carlo Di Mario 1:30 pm - Case Review 4: How to Perform the Simultaneous Kissing Stent Technique in a Complex Bifurcation Sorin J. Brener 1:45 pm - Adjourn Complication Management (Part 2) 12:15 pm-1:45 pm Room 122 Moderators: Nick Curzen, Richard R. Heuser, John R. Laird Jr Discussants: Rajesh M. Dave, James D. Joye, Thomas O. McNamara, Craig A. Thompson, Gerald S. Werner, R. Michael Wyman Session I. Complications Associated with Treating Coronary CTOs: A Series of Case Reviews 12:15 pm - Complications Arising During the Antegrade Approach to CTOs Craig A. Thompson 12:25 pm - Complications Arising During the Retrograde Approach to CTOs R. Michael Wyman 1:25 pm - Discussion 12:35 pm - Perforations Associated with CTO Treatment: All Types Gerald S. Werner 1:30 pm - HCM and Aortic Stenosis: Is Ablation Ever Right? Case Presenter: Srihari S. Naidu 12:45 pm - Minimizing Complications Associated with Treating CTOs Richard R. Heuser 1:40 pm - Discussion Session II. Peripheral Vascular Complications: Cases, Examples, and Tips and Tricks 1:45 pm - Adjourn Complex Bifurcations 12:15 pm-1:45 pm Room 113 Moderator: Issam D. Moussa Discussants: Sorin J. Brener, Alaide Chieffo, Ricardo A. Costa, Carlo Di Mario, Ioannis Iakovou 12:15 pm - What Is a “Complex Bifurcation”? Issam D. Moussa 12:30 pm - How to Perform Provisional Stenting in Complex Bifurcations: A Roadmap for Success Alaide Chieffo 130 12:45 pm - Case Review 1: What to Do When the Sidebranch Occludes During Provisional Stenting? Ricardo A. Costa program · 12:55 pm - Complications Associated with Aortoiliac Intervention John R. Laird Jr 1:05 pm - Complications Associated with Femoropopliteal Intervention James D. Joye 1:15 pm - Infrapopliteal Intervention: Complications and Their Treatment Thomas O. McNamara 1:25 pm - Complications Associated with Treating Critical Limb Ischemia Rajesh M. Dave T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Day-to-Day Use of FFR 12:15 pm-1:45 pm Room 121 Session I. Clinical Applications of FFR Moderators: Bon-Kwon Koo, Massoud A. Leesar Discussants: Takashi Akasaka, Michalis Hamilos, Allen Jeremias 12:15 pm - How to Integrate FAME, SYNTAX, COURAGE, and PROSPECT into Daily Practice Bernard De Bruyne 12:27 pm - Why FFR in Left Main and Bifurcation Lesions? Bon-Kwon Koo 12:39 pm - Discussion with Audience Q&A Session II. The Art and Technique of FFR Measurement: Case Review Session Moderators: Bon-Kwon Koo, Massoud A. Leesar 12:50 pm - FFR in Bifurcation Lesions Massoud A. Leesar 1:00 pm - FFR in Complex Lesions Pim A.L. Tonino 1:10 pm - FFR in Acute Coronary Syndromes Habib Samady 1:20 pm - FFR in Left Main Stenosis Gregory R. Giugliano 1:30 pm - FFR in Tandem Lesions William F. Fearon 1:40 pm - Take-Home Messages Bon-Kwon Koo, Massoud A. Leesar 1:45 pm - Adjourn Percutaneous Edge-to-Edge Mitral Valve Repair 12:15 pm-1:45 pm Room 111 Step I. TTE and TEE Pre-procedural Assessment to Identify Appropriate Mitral Valve Pathology for the MitraClip Moderators: James B. Hermiller Jr, Scott Lim Discussant: Neil J. Weissman 12:15 pm - Case 1: Degree of MR Assessment Neil J. Weissman 12:23 pm - Case 2: Complex Degenerative Pathology Neil J. Weissman The World’s Premier Interventional Experience TCT2011 Moderators: James B. Hermiller Jr, Scott Lim Discussant: Gorav Ailawadi 12:38 pm - Case 2: How to Gain Height After Inferior Transseptal Gorav Ailawadi Step III. Transseptal Puncture for the MitraClip Moderators: James B. Hermiller Jr, Scott Lim Discussant: Francesco Maisano 12:45 pm - Case 1: How to Puncture the Bulging Septum Francesco Maisano 12:53 pm - Case 2: How to Puncture the Floppy Septum Francesco Maisano Step IV. Steering/Guidance/Grasping of Leaflets Moderators: James B. Hermiller Jr, Scott Lim 1:00 pm - Case 1: Using 2-D TEE to Guide the Clip Scott Lim 1:08 pm - Case 2: Using 3-D TEE to Guide the Clip Scott Lim Step V. MR Evaluation Post-Clip and Decision for Second Clip Moderators: James B. Hermiller Jr, Scott Lim Discussant: Olaf Franzen 1:15 pm - Case 1: 2+ MR and Mild Inflow Gradient Olaf Franzen 1:23 pm - Case 2: Getting Fooled by Residual MR Olaf Franzen Step VI. Dealing with Complications Moderators: James B. Hermiller Jr, Scott Lim Discussant: Richard Smalling 1:30 pm - Case 1: Stuck in Chords Richard Smalling 1:38 pm - Case 2: The Unexpected Richard Smalling 1:45 pm - Adjourn Transradial Intervention 12:15 pm-1:45 pm Room 112 Moderators: Philippe Genereux, Tift Mann Discussants: Ivo Bernat, Olivier F. Bertrand, Vladimir Dzavik, Ian C. Gilchrist, Tak W. Kwan, Ramon Quesada, Sunil V. Rao 12:15 pm - Introduction Philippe Genereux, Tift Mann 12:45 pm - Laser and Radiofrequency Ablation for Superficial Venous Disease Jose M. Wiley 12:28 pm - Bifurcation Stenting with 6 Fr Guide Vladimir Dzavik 12:51 pm - Acute Deep Venous Thrombosis 1 Mahmood K. Razavi 12:37 pm - Subacute Radial Occlusion Treated with Transient Ulnar Compression Ivo Bernat 12:57 pm - Acute Deep Venous Thrombosis 2 Anthony J. Comerota 12:46 pm - PCI via Radial Access in STEMI Olivier F. Bertrand 12:55 pm - Ad Hoc NSTEMI PCI with Switch to Bivalirudin Sunil V. Rao 1:04 pm - TRI in the Post-CABG Patient: Left Radial Access and Setup Tift Mann 1:13 pm - Techniques to Traverse Difficult Arm/ Shoulder/Ascending Aorta Anatomy Ian C. Gilchrist 1:22 pm - Management of Radial Complications Philippe Genereux 1:31 pm - CTO PCI via Transradial Access: Setup and Technique Ramon Quesada 1:40 pm - Take-Home Messages Philippe Genereux, Tift Mann 1:45 pm - Adjourn Venous Disease Intervention 12:15 pm-1:45 pm Room 114 Session I. Core Concepts Moderators: Raghu Kolluri, Mahmood K. Razavi 12:15 pm - Venous Anatomy, Physical Exam, and Assessment Raghu Kolluri 12:23 pm - Evidence Supporting Ablative Therapies in Superficial Venous Disease Anthony J. Comerota 12:28 pm - Evidence Supporting Intervention in Acute Proximal Deep Venous Thrombosis Greg Mishkel 12:35 pm - Evidence Supporting Intervention in Chronic Venous Occlusions Mahmood K. Razavi 12:40 pm - Evidence for Interventional Management of Submassive and Massive Pulmonary Emboli Lawrence Hofmann Session II. The Cases Moderators: Raghu Kolluri, Mahmood K. Razavi Discussants: Anthony J. Comerota, Lawrence Hofmann, Greg Mishkel, Jose M. Wiley 1:03 pm - Upper Extremity Central Venous Occlusion Greg Mishkel 1:09 pm - Chronic Deep Venous Thrombosis Mahmood K. Razavi 1:15 pm - Complications of Venous Intervention Greg Mishkel - N o v e m b e r 1 0 , 2 0 11 12:30 pm - Case 1: How to Get Coaxial After Anterior Transseptal Gorav Ailawadi 12:19 pm - Complex PCI Using 7 Fr Sheathless Technique Tak W. Kwan Thursday Step II. Mechanics and Knobs of the MitraClip System T r a n s c at h e t e r Cardiovascular Therapeutics 1:21 pm - Pulmonary Embolism Lawrence Hofmann 1:27 pm - Something You Don’t See Everyday Raghu Kolluri 1:33 pm - Discussion with Audience Q&A 1:45 pm - Adjourn Afternoon Spotlight Sessions Deep Dive: Interventional Hypertension 2:00 pm-6:00 Room 135 pm Part I. Hypertension Overview Moderators: John Flack, C. Venkata S. Ram Discussants: Prakash Deedwania, Maurizio Menichelli, Addison A. Taylor 2:00 pm - Demographics and Epidemiology of Hypertension: End-Organ Effects and Clinical Consequences C. Venkata S. Ram 2:12 pm - Discussion 2:15 pm - Monitoring and Measuring Blood Pressure: Defining the Resistant (Refractory) Hypertensive Patient Addison A. Taylor 2:27 pm - Discussion 2:30 pm - Standard Hypertension Therapy: Guidelines for Optimal Pharmacotherapy, Diet, and Lifestyle Modifications John Flack 2:42 pm - Discussion 2:45 pm - Current Approaches to Resistant Hypertension: Clinical Workup and Treatment Strategies Henry Black www.tctconference.com 131 Thursday, November 10 2:57 pm - Discussion 5:27 pm - Discussion 3:00 pm - Hypertension Centers of Excellence: A Team Approach Improves Outcomes John Flack 5:30 pm - Future Research Targets for Renal Denervation Therapy: Heart Failure and Sleep Apnea Henry Krum 3:12 pm - Discussion 3:15 pm - Role of the Kidney and RAAS Activation in Hypertension Prakash Deedwania 3:27 pm - Discussion 3:30 pm - Sympathetic Nervous System Activation and Hypertension Prakash Deedwania 3:42 pm - Discussion 3:45 pm - Moderated Panel Discussion: Focus on Resistant Hypertension: Magnitude of the Problem and Therapeutic Challenges Part II. Interventional Hypertension Therapy Moderators: Deepak L. Bhatt, Horst Sievert Discussants: Robert Kieval, Henry Krum, Felix Mahfoud, Christopher D. Owens 4:00 pm - Background and Rationale for Renal Denervation Therapy in Refractory Hypertension Henry Krum 4:12 pm - Discussion 4:15 pm - Latest Results from Renal Denervation Therapy in Refractory Hypertension: The Symplicity HTN-1 and Symplicity HTN-2 Trials Horst Sievert 4:27 pm - Discussion 4:30 pm - Lessons Learned and Trial Design for the United States Pivotal Symplicity HTN-3 Trial Deepak L. Bhatt 4:42 pm - Discussion 4:45 pm - The CVRx Implantable Carotid Sinus Modulation System to Treat Refractory Hypertension: Rationale and Clinical Trial Results Robert Kieval 4:57 pm - Discussion 5:00 pm - Adventitial Drug-Induced Renal Artery Denervation in Refractory Hypertension: Preclinical Experience and First-in-Human Status Update (MERCATOR) Christopher D. Owens 132 5:43 pm - Discussion 5:45 pm - Moderated Panel Discussion: Pitfalls and Promise for Ardian and Other DeviceBased Therapies for Refractory Hypertension 6:00 pm - Adjourn Drug-Coated Balloons: Clinical Data and Applications 2:00 pm-6:00 Room 133 pm Session I. Specific Devices and Latest Results Moderators: Juan F. Granada, Detlef G. Mathey Discussants: Giancarlo Biamino, Bodo Cremers, Hans Krankenberg, Bruno Scheller, Karl Ludwig Schulte, Pieter R. Stella, Thomas Zeller 2:00 pm - Paccocath: Technology Overview and Latest Peripheral Data Thomas Zeller 2:15 pm - Paccocath Cotavance/SeQuent Please: Latest Coronary Data Bruno Scheller 2:27 pm - Discussion with Audience Q&A: Critical Appraisal of the Paccocath Technology and Results 2:39 pm - Eurocor: Technology Overview and Latest Peripheral Data Karl Ludwig Schulte 2:49 pm - Eurocor: Latest Coronary Data Pieter R. Stella 2:57 pm - Discussion with Audience Q&A: Critical Appraisal of the Eurocor Technology and Results 3:03 pm - Invatec: Technology Overview and Latest Peripheral Data Giancarlo Biamino 3:13 pm - Invatec: Latest Coronary Data Bodo Cremers 3:21 pm - Discussion with Audience Q&A: Critical Appraisal of the Invatec Technology and Results 5:12 pm - Discussion 3:27 pm - Pantera Lux: Technology and Data Ralph Toelg 5:15 pm - Impact of Renal Denervation Therapy on Glucose Metabolism, Insulin Resistance, and Diabetes Felix Mahfoud 3:37 pm - Lutonix: Technology Overview and Latest Peripheral Data Hans Krankenberg program · 3:45 pm - Lutonix: Latest Coronary Data Patrick W. Serruys T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 3:51 pm - Discussion with Audience Q&A: Critical Appraisal of the Lutonix Technology and Results 4:01 pm - Progress with a Drug-Coated Angiosculpt Gary Gershony 4:11 pm - Unique Coatings and Novel Carrier-Systems to Enable a SirolimusBased Drug-Coated Balloon: Descriptions and Preclinical Data Greg L. Kaluza 4:21 pm - PERFECT Stent Study 12-Month Results: Paclitaxel-coated Balloon Plus Endothelial Progenitor Cell Capturing Stents in De Novo Coronary Artery Disease Jochen Wöhrle 4:33 pm - Discussion with Audience Q&A Discussants: Gary Gershony, Greg L. Kaluza, Ralph Toelg, Jochen Wöhrle Session II. Case Reviews: Complex Drug-Coated Balloon Cases Moderators: Alessandro S. Bortone, Upendra Kaul Discussants: Jorge Gaspar, Barry T. Katzen, Alfredo Rodriguez, Konstantinos Spargias, Jean-François Tanguay 4:48 pm - Peripheral Case 1 Giuseppe M. Sangiorgi 4:56 pm - Peripheral Case 2 Robert A. Byrne 5:04 pm - Coronary Case 1 Azeem Latib 5:12 pm - Coronary Case 2 Tian-Hai Koh Session III. Summary Statements Moderators: Ron Waksman, Thomas Zeller 5:20 pm - Evidence-based Medicine Synthesis 2011: DCBs for Peripheral Arterial Applications: Promise, Caveats, and Recommendations for Further Development Hans Krankenberg 5:35 pm - Evidence-based Medicine Synthesis 2011: DCBs for Coronary Arterial Applications: Promise, Caveats, and Recommendations for Further Development Bruno Scheller 5:50 pm - The Last Word: “Top Five Facts” That May Kill This Technology— If We’re Not Careful! Juan F. Granada 6:00 pm - Adjourn The World’s Premier Interventional Experience TCT2011 2:00 pm-6:15 Room 134 pm 2:00 pm - The World of 3-D OCT Patrick W. Serruys 2:15 pm - Introduction to OCT Image Interpretation Guillermo Tearney 2:27 pm - Pre-intervention OCT Cases 1 Konstantinos Toutouzas 2:37 pm - Pre-intervention OCT Cases 2 Hiroyuki Okura 2:47 pm - Post-intervention OCT Cases 1 Marco A. Costa 2:57 pm - Post-intervention OCT Cases 2 Francesco Prati 3:07 pm - Stent Failure OCT Cases 1 Gilles Rioufol 3:17 pm - Stent Failure OCT Cases 2 Maria D. Radu 3:27 pm - Next Generation OCT and Beyond Brett E. Bouma 3:37 pm - Discussion Panel: OCT Image Interpretation: What Is Certain and What Is Not Session II. NIRS Image Interpretation: Case Presentations and Panel Interpretations Moderators: James A. Goldstein, Morton J. Kern Discussants: Emmanouil S. Brilakis, Hector M. Garcia-Garcia, Henning Kelbaek, Brij Maini, Pedro R. Moreno, Evelyn S. Regar, Giora Weisz 3:52 pm - NIR Spectroscopy and Image Interpretation (with Integrated IVUS): Beneath the Pixels James E. Muller 4:05 pm - Pre-intervention NIR Cases 1 Brij Maini 4:15 pm - Pre-intervention NIR Cases 2 David G. Rizik 4:25 pm - Post-intervention NIR Cases Emmanouil S. Brilakis Session III. Clinical Potential of Intravascular Optical Imaging Moderators: Gary S. Mintz, Patrick W. Serruys Discussants: Fernando Alfonso, YunDai Chen, Marc D. Feldman, Peter J. Fitzgerald, Giulio Guagliumi, Michael Joner, Takashi Kubo 4:45 pm - Angiography Alone is Not Sufficient for Cath Lab Decision-Making: The Need for Direct Coronary Imaging James A. Goldstein 4:55 pm - Optical Imaging in Acute Coronary Syndromes Atsushi Tanaka 5:10 pm - Optical Imaging to Guide Interventions Junya Shite 5:25 pm - Optical Imaging to Prevent and Assess Immediate Stent Complications Evelyn S. Regar 5:35 pm - Optical Imaging to Prevent and Assess Late Stent Complications Giulio Guagliumi 5:50 pm - In-Stent Neoatherosclerosis: Pathologic Validation, Imaging Insights, and Clinical Findings Gary S. Mintz 6:00 pm - Panel Discussion: Intravascular Optical Imaging: What Is Needed to Further the Clinical Adoption of These Technologies? 6:15 pm - Adjourn Optimizing Primary PCI for STEMI (Part 2): Drugs, Devices, and Techniques 2:00 pm-6:15 Room 104 pm Session I. Management of Thrombus Moderators: Bruce R. Brodie, Chaim S. Lotan Discussants: David Antoniucci, Francesco Burzotta, Joost Daemen, Holger Thiele 2:00 pm - Does Aspiration Really Reduce Mortality? A Critical Appraisal Francesco Burzotta 2:10 pm - Rheolytic Thrombectomy: Explaining the Differences Between AiMI and JETSTENT David Antoniucci 2:20 pm - Intracoronary Glycoprotein IIb/IIIa Platelet Inhibitors: A New Way to Give an Old Drug Holger Thiele 2:30 pm - Stent Thrombosis After Primary PCI: Frequency, Predictors, and Strategies to Prevent Joost Daemen 2:40 pm - Discussion with Audience Q&A Session II. Procedural Management Choices During Primary PCI for STEMI: A Series of Flash Debates Moderators: Petr Kala, Harvey D. White Discussants: Graham A. Cassel, Giuseppe De Luca, Sameer Mehta, Fayaz Shawl, Marco V. Wainstein, Bernhard Witzenbichler Flash Debate I. DES Should Be Used Liberally in STEMI Patients Treated with Primary PCI - N o v e m b e r 1 0 , 2 0 11 Session I. OCT Image Interpretation: Case Presentations and Panel Interpretations Moderators: Giulio Guagliumi, Evelyn S. Regar Discussants: Takashi Akasaka, Francesco Burzotta, Marco A. Costa, Carlo Di Mario, Sheldon Goldberg, Maria D. Radu, Neil J. Weissman 4:35 pm - Discussion Panel: NIRS Imaging and Clinical Applications: What Is Certain and What Is Not Thursday Next Generation Optical Intravascular Imaging: OCT and NIR Spectroscopy T r a n s c at h e t e r Cardiovascular Therapeutics 2:50 pm - Pro: The Data Couldn’t Be More Solid! Somjot S. Brar 2:58 pm - Con: Little to Gain and a Lot to Lose! Bruce R. Brodie 3:06 pm - Discussion with Audience Q&A Flash Debate II. Transradial Should Be the Preferred Access Route in STEMI Patients 3:10 pm - Pro: Eliminate Bleeding, Improve Outcomes (and Patient Comfort)! Marco Valgimigli 3:18 pm - Con: Bivalirudin Plus Femoral Access Preserves My Options—and Is Faster! David A. Cox 3:26 pm - Discussion with Audience Q&A Flash Debate III. Bivalir udin Is the New Standard of Care for Primary PCI 3:30 pm - Pro: It Has the Highest Level of Evidence in Both the EU and US Guidelines! Michel R. Le May 3:38 pm - Con: Heparin (Unfractionated or LMWH) Plus GP IIb/IIIa Inhibitors Are Better! Sanjit S. Jolly 3:46 pm - Discussion with Audience Q&A Session III. Primary PCI Technique and Challenges Moderators: Cindy L. Grines, Marco Valgimigli Discussants: Simon R. Dixon, Elvin Kedhi, Ajay J. Kirtane, Michael Mooney, William W. O’Neill, Manesh R. Patel, Pascal Vranckx 3:50 pm - Management of (Left and Right Ventricular) Cardiogenic Shock During Primary PCI: 2011 Approaches and Outcomes Simon R. Dixon 4:00 pm - Use of Impella During Cardiogenic Shock William W. O’Neill www.tctconference.com 133 Thursday, November 10 4:08 pm - Rationale for Left Ventricular Unloading with Impella to Reduce Infarct Size: The MINI-AMI Trial Ajay J. Kirtane 4:15 pm - Use of Intraaortic Balloon Counterpulsation Before or After Primary PCI in High-Risk STEMI: From PAMI-2 to CRISP-AMI Manesh R. Patel 4:25 pm - Management of STEMI Patients with Multivessel Disease: From Current Recommendations to the COMPARE-ACUTE Trial Elvin Kedhi 4:35 pm - Considerations for STEMI Patients Taking Oral Anticoagulants Pascal Vranckx 4:43 pm - Benefits of Hypothermia in Cardiac Arrest Survivors—and Practical Recommendations Michael Mooney 4:53 pm - Discussion with Audience Q&A Session IV. Approaches to Reperfusion Injury and Enhancing Myocardial Recovery Moderators: Mitchell W. Krucoff, Holger Thiele Discussants: Thomas Engstrom, David Erlinge, Christopher B. Granger, Robert A. Kloner, Frans Van de Werf 5:05 pm - Reperfusion Injury in 2011: Does It Exist, and What Can We Do About It? Robert A. Kloner 5:15 pm - Failed Approaches to Reduce Infarct Size, and Why Do They Keep Failing?! Christopher B. Granger 5:25 pm - Potential for Improved Myocardial Reperfusion with a PTFE Net-Covered Stent: Rationale and MASTER Trial Design Dariusz Dudek 5:33 pm - Intracoronary Adenosine During Primary PCI: Are the Data Strong Enough to Recommend Routine Use? Frans Van de Werf 5:43 pm - Studies of Hypothermia to Reduce Infarct Size David Erlinge Complex Coronary Intervention Great Cases Special Twilight Sessions Partnership Session: Brazilian Society of Interventional Cardiology (SBHCI) and Gi2: Transcatheter Aortic Valve Replacement and Complex Coronary Intervention 6:00 pm-8:00 Room 123 pm 6:00 pm - Opening Remarks Moderators: Andrea Abizaid, Gregg W. Stone Session I. Transcatheter Aortic Valve Replacement Moderators: Mauricio R. Barbosa, Carlos Pedra Discussants: Fabio S. Brito, Augusto D. Pichard, E. Murat Tuzcu 6:05 pm - How to Start a TAVR Program: From Fundamentals, to Training, to Putting Together the Valve Team Augusto D. Pichard 8:00 pm - Adjourn Partnership Session: p-c-i Live in Partnership with TCT: Practical Aspects of Coronary, Valvular, and Electrophysiologic Interventions 6:00 pm-8:00 Room 122 pm 6:00 pm - Introduction to PCI Live Moderators: Martin B. Leon, Sigmund Silber 6:10 pm - PCI vs. Bypass Surgery: The European View: State of the Art Sigmund Silber 6:35 pm - Discussion with Audience Q&A 6:20 pm - Edited Case Presentation: Highly Proximal LAD in a Diabetic Patient Jochen Wöhrle TAVR Great Cases Discussants: Luiz Antonio Carvalho, Pedro A. Lemos, Jose Armando Mangione, Augusto D. Pichard 6:45 pm - Case 1: Unusual Unexpansion of CoreValve Surgically Explanted Rogerio Sarmento-Leite 6:53 pm - Case 2: Valve-in-Valve Augusto D. Pichard 7:01 pm - Case 3: No Vascular Access Magaly Arrais dos Santos 6:01 pm - Novel Approaches to Reduce Infarct Size: Cyclosporin, Preconditioning, and Postconditioning Thomas Engstrom 7:09 pm - Complex Lesion Morphologies: Left Main and Acute MI Davide Capodanno program · 7:52 pm - Case 3: Bioabsorbable Scaffold Jose de Ribamar Costa Jr 6:25 pm - SBHCI Recommendations for TAVR Case Selection Fabio S. Brito 7:19 pm - New DES Technologies Including Fully Bioabsorbable Scaffolds Alexandre Abizaid 7:29 pm - Discussion with Audience Q&A 134 7:44 pm - Case 2: Acute MI Marco V. Wainstein 6:15 pm - How to Avoid the Most Common Complications: Vascular, Bleeding, and Stroke E. Murat Tuzcu Session II. Complex Coronary Intervention Moderators: Expedito E. Ribeiro, Amanda G.M.R. Sousa Discussants: Alexandre Abizaid, Davide Capodanno 6:15 pm - Adjourn 7:36 pm - Case 1: Left Main Marco A. Perin Session I. Coronary Intervention Moderators: Jochen Cremer, Sigmund Silber Discussants: Wolfgang Bocksch, Juerg Gruenenfelder, Kurt Huber, Florin Laubenthal, Gerald S. Werner, Jochen Wöhrle 5:53 pm - Effects of Pressure-Controlled Intermittent Coronary Sinus Occlusion on Myocardial Reperfusion: Preparing for PREPARE-RAMSES Jan J. Piek 6:13 pm - Discussion with Audience Q&A Discussants: Marcelo Jose de Carvalho Cantarelli, Fausto Feres, Gilberto Lahorgue Nunes, Marco V. Wainstein T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 6:30 pm - Discussion with Audience Q&A 6:40 pm - Take-Home Messages Bernhard Witzenbichler Session II. Valvular Intervention Moderators: Hans R. Figulla, Friedrich W. Mohr Discussants: Wolfgang Bocksch, Juerg Gruenenfelder, Kurt Huber, Joachim Schofer, Horst Sievert, Gerald S. Werner 6:45 pm - TAVI vs. Traditional Aortic Valve Implantation: The European View: State of the Art Hans R. Figulla 6:55 pm - Edited Case Presentation: Aortic Stenosis in a 60-Year-Old Patient Wolfgang Bocksch 7:05 pm - Discussion with Audience Q&A 7:15 pm - Take-Home Messages Joachim Schofer The World’s Premier Interventional Experience TCT2011 7:30 pm - Edited Case Presentation: Persistent Atrial Fibrillation in a Young Patient Thorsten Lewalter 7:40 pm - Discussion with Audience Q&A 7:50 pm - Take-Home Messages Ernst Vester 8:00 pm - Adjourn Practicalities and Pitfalls of Platelet Function Testing 6:00 pm-8:00 pm Room 120 Moderators: Dominick J. Angiolillo, Paul A. Gurbel, Matthew J. Price Discussants: Laurent Bonello, Dirk Sibbing, Tabassome Simon, Jurrien M. Ten Berg 6:00 pm - Platelet Reactivity and Outcomes After PCI: Current State of the Evidence Dominick J. Angiolillo Assessing the Prognostic and Predictive Value of Platelet Function Testing in Patients Undergoing PCI: Is It a Meaningful Test? 6:10 pm - Viewpoint 1: Perhaps, but with Little Clinical Use! Jurrien M. Ten Berg 6:22 pm - Viewpoint 2: Yes, If You Know How to Interpret the Test! Paul A. Gurbel 6:34 pm - Discussion with Audience Q&A 6:44 pm - Platelet Function Testing in the Low-Risk Patient: Lessons Learned From GRAVITAS and TRIGGER-PCI Matthew J. Price 6:56 pm - Incorporating Platelet Function Testing into a Practical Clinical Pathway Laurent Bonello 7:08 pm - Discussion with Audience Q&A 7:18 pm - Optimizing Platelet Inhibition to Prevent Bleeding Complications with Platelet Function Testing (Timing of Surgery After DAPT Discontinuation; Long-term Antiplatelet Therapy Management): Are We There Yet? Dirk Sibbing TCT Mediterranean 7:05 pm - A Distal Left Main Bifurcation Mohamed Sobhy 7:45 pm - Discussion with Audience Q&A 6:00 pm-8:00 pm Room 121 Moderators: George D. Dangas, Roxana Mehran 6:00 pm - Welcome and Introduction: Goals and Plans for TCT in the Mediterranean Region George D. Dangas Session I. Imaging/FFR Update in the Mediterranean Region: State of the Union Moderators: Panayiotis Avraamides, George D. Dangas Discussants: Dariusz Dudek, Oktay Ergene, Zaza Kavteladze, Nicholas N. Kipshidze, Milan A. Nedeljkovic, Konstantinos Toutouzas, Dobrin Vassilev 6:05 pm - Case Presentation: Invasive Imaging Solves a Dilemma Konstantinos Toutouzas 6:10 pm - How I Use IVUS/VH in Clinical Practice Nicholas N. Kipshidze 6:15 pm - How I Use OCT in Clinical Practice Dariusz Dudek 6:20 pm - How I Use FFR in Clinical Practice Milan A. Nedeljkovic 6:25 pm - Discussion with Audience Q&A Session II. TAVR in the Mediterranean Region: Investigations and Clinical Penetration Moderators: Chaim S. Lotan, Gennaro Sardella Discussants: Christos Christou, Ghada W. Mikhail, Anna Sonia Petronio, Boris Starcevic, Corrado Tamburino 7:10 pm - Approach to Bifurcations: How to Choose Between a Provisional vs. Planned Two Stent Strategy Archimides Sanati 7:15 pm - Approach to Left Main Disease: Who Should Have PCI Rather Than CABG? Andrejs Erglis - N o v e m b e r 1 0 , 2 0 11 7:20 pm - Ablation vs. Medical Treatment in Atrial Fibrillation: The European View: State of the Art Ernst Vester 8:00 pm - Adjourn Session III. Left Main and Bifurcations: The Mediterranean Experience Moderators: Thierry Corcos, Aleksander Ernst Discussants: Ibrahim R. Al-Rashdan, Andrejs Erglis, Georges Ghanem, Archimides Sanati, Mohamed Sobhy 7:30 pm - Synthesizing the Assessment of Genotype and Phenotype in the PCI Patient Tabassome Simon Thursday Session III. Electrophysiologic Intervention Moderators: Juerg Gruenenfelder, Thorsten Lewalter Discussants: Kurt Huber, Karl-Heinz Kuck, Florin Laubenthal, Ernst Vester, Gerald S. Werner T r a n s c at h e t e r Cardiovascular Therapeutics 7:20 pm - Discussion with Audience Q&A Session IV. Complex PCI: Tackling the Complications Moderators: Roxana Mehran, Antonios A. Polydorou Discussants: Ozgen Dogan, Ahmed Magdy, Luigi Salemme, Giuseppe M. Sangiorgi 7:30 pm - Case Presentation 1: A Severe Perforation Luigi Salemme 7:35 pm - Case Presentation 2: No Reflow Ahmed Magdy 7:40 pm - Case Presentation 3: Stent Thrombosis Giuseppe M. Sangiorgi 7:45 pm - Discussion with Audience Q&A Closing Remarks and Future Plans Moderator: Roxana Mehran 8:00 pm - Adjourn Evening Programs 7:00 pm -10:00 pm Please see page 161 for Evening Programs schedule. 6:35 pm - Case Presentation: A Typical TAVR Case in My Hospital Ghada W. Mikhail 6:40 pm - TAVR Tips and Tricks for Case Selection and Technique Corrado Tamburino 6:50 pm - How to Avoid Stroke and Bleeding Complications in TAVR Anna Sonia Petronio 6:55 pm - Discussion with Audience Q&A www.tctconference.com 135 TCT Comes to Miami in 2012 Save the date OCTOber 22-26, 2012 Mi ami Bea ch Co nv en tion Cent er MiaMi, florida w w w. t ct con f e re n c e . c o m The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Major Halls Main Arena............................................................................................... 138 How to Treat Theater: Coronary Artery Disease....................................... 139 How to Treat Theater: Endovascular and Structural Heart Disease.......... 139 Challenging Case Multiplex Challenging Case Theater........................................................................ 140 International Society-Sponsored Case Theater........................................ 140 Morning Spotlight Sessions Controversies in Interventional Cardiology: The Skeptic’s Corner............ 140 Difficult Patients in Interventional Cardiology: The Art of Clinical Decision-Making......................................................... 141 TAVR Site Readiness: Organizing and Training Your Site to Prepare for TAVR................................................................... 142 Friday Breakfast Meetings........................................................................... 162 the Moscone Center · san francisco, ca November 11, 2011 www.tctconference.com 137 Friday, November 11 Breakfast Meetings 7:00 am -8:00 am Please see page 162 for the Breakfast Meetings schedule. 10:30 am - State of the Subspecialty: Dynamic Changes in Resource Allocation, Physician Training, and Socioeconomic Imperatives John C. Lewin 10:45 am - Discussion Plenary Session XX. TCT 2011 Geoffrey O. Hartzler Master Clinical Operator Award Main Arena 8:00 am-3:00 pm Esplanade Ballroom Plenary Session XVIII. Live Cases VII Live Case Moderator: Martin B. Leon Live Case Co-Moderator: Antonio Colombo Live Case Discussants: Mauricio Cohen, Efrain Gaxiola, J. Aaron Grantham, Reginald I. Low, Brad I. Munt, Christoph A. Nienaber, Raghotham R. Patlola, Stephen R. Ramee, Mahmood K. Razavi, Peter C. Smits, Christopher K. Zarins 8:00 am - University Hospital Bonn Bonn, Germany 8:45 am - Park Hospital Leipzig Leipzig, Germany Plenary Session XIX. Interventional TCT-ACC Masters Collection Moderators: Ralph G. Brindis, Gregg W. Stone Discussants: Simon R. Dixon, Juan F. Granada, Liliana R. Grinfeld, Jose P.S. Henriques, Neal S. Kleiman, David W.M. Muller, Marc E. Shelton, Frans Van de Werf, Glenn Van Langenhove, David O. Williams 9:30 am - Evolution of Diagnosis and Treatment of Vulnerable Plaque: From PROSPECT to the High-Risk Plaque Project Valentin Fuster 9:45 am - Discussion 9:50 am - Improving Outcomes in the High-Risk STEMI Patient: Systems, Cells, and Devices Cindy L. Grines 10:50 am - Presentation of the TCT 2011 Geoffrey O. Hartzler Master Clinical Operator Award Award Presenters: Martin B. Leon, Gregg W. Stone Award Recipient: Horst Sievert Plenary Session XXI. Late Breaking Clinical Trials and First Report Investigations III Focus on Novel Drug-Eluting Stents and Drug-Coated Balloons Moderator: Gregg W. Stone Discussants: Alexandre Abizaid, Didier Carrie, Antonio Colombo, Stéphane Cook, Joost Daemen, Juan F. Granada, Michael Haude, Michael Joner, Laura Mauri, Ian T. Meredith, Harald Rittger, Patrick W. Serruys 11:00 am - EVOLVE: A Prospective, Randomized Trial of Two Dose Formulations of a Bioabsorbable PolymerBased Everolimus-Eluting Stent vs. a Durable Polymer-Based Everolimus-Eluting Stent Ian T. Meredith 11:10 am - REMEDEE: A Prospective, Randomized Trial of a Combination Bioabsorbable PolymerBased Anti-CD34 Antibody Sirolimus-Eluting Stent vs. a Durable Polymer-Based PaclitaxelEluting Stent Michael Haude 10:05 am - Discussion 11:20 am - NEXT: A Prospective, Randomized Trial Comparing Cre8, a Polymer-Free Stent Eluting Sirolimus, to a Paclitaxel-Eluting Stent 10:10 am - Vascular Restoration with Bioabsorbable Drug-Eluting Stents Are the Future! The Science Behind the Dream Patrick W. Serruys 10:25 am - Discussion 138 program · Didier Carrie T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 11:30 am - PEPCAD-DES: A Prospective, Randomized Trial of a PaclitaxelCoated Balloon vs. Uncoated Balloon Angioplasty in Patients with Restenosis of Drug-Eluting Stents Harald Rittger 11:40 am - Roundtable Discussion: Strengths, Limitations, and Implications of These Studies Focus on Optimal PCI Moderator: Michalis Hamilos Discussants: Jozef Bartunek, Justin Davies, Andrejs Erglis, William F. Fearon, John McB. Hodgson, Henning Kelbaek, Morton J. Kern, Gary S. Mintz, Keith G. Oldroyd, Mark Reisman, Gert Richardt, Pim A.L. Tonino, Clemens von Birgelen 11:55 am - TWENTE: A Prospective, Randomized Trial of Zotarolimus-Eluting Stents and EverolimusEluting Stents in Patients with Coronary Artery Disease Clemens von Birgelen 12:05 pm - ROTAXUS: A Prospective, Randomized Trial of High-Speed Rotational Atherectomy Prior to Paclitaxel-Eluting Stent Implantation in Complex Calcified Coronary Artery Lesions Gert Richardt 12:15 pm - ADVISE: Validation of a Vasodilator-Independent Measure of Coronary Fractional Flow Reserve Justin Davies 12:25 pm - Roundtable Discussion: Strengths, Limitations, and Implications of These Studies Focus on Peripheral Vascular Disease Moderator: Thomas Zeller Discussants: J. Michael Bacharach, Subhash Banerjee, Robert M. Bersin, Peter S. Fail, Michel Henry, Raghu Kolluri, Hans Krankenberg, D. Christopher Metzger, Stephen R. Ramee, Mahmood K. Razavi, Joachim Schofer, Mark H. Wholey, Jay S. Yadav The World’s Premier Interventional Experience TCT2011 Carotid Stenting Klaudija Bijuklic 1:00 pm - Roundtable Discussion: Strengths, Limitations, and Implications of These Studies Plenary Session XXII. TCT 2011 Highlights and Take-Home Messages Moderators: Martin B. Leon, Gregg W. Stone Discussants: John A. Bittl, David J. Cohen, Antonio Colombo, Michael J. Cowley, Dariusz Dudek, Ajay J. Kirtane, Roxana Mehran, Gary S. Mintz, Jeffrey W. Moses, Manish A. Parikh, Patrick W. Serruys 1:10 pm - TCT 2011 Late Breaking Trials Critique and Interpretation Gregg W. Stone 3:00 pm - Adjourn How to Treat Theater: Coronary Artery Disease 8:00 am-12:30 Hall D pm Live Case Moderator: Jeffrey W. Moses Live Case Co-Moderator: Rajesh M. Dave Live Case Discussants: Daniel H. Berrocal, Pawel E. Buszman, Edoardo Camenzind, Louis A. Cannon, Lei Ge, Jan J. Piek, Duane S. Pinto, George W. Vetrovec, Wojciech Wojakowski 8:30 am - Piedmont Heart Institute Atlanta, GA 10:00 am - Discussion: What Have We Learned from These Cases? Complex and Unusual Cases IV Moderator: Ajay J. Kirtane Co-Moderator: Kirk N. Garratt 10:15 am - The Exploding World of Intravascular Imaging: Rational Assimilation into Today’s Cath Lab Environment Gary S. Mintz 10:30 am - Radial vs. Femoral Access Revisited: Major Distinction or Much Ado About Nothing? Martial Hamon Live Cases: Complex and Unusual Cases IV Live Case Moderator: Ajay J. Kirtane Live Case Discussants: Periklis Davlouros, Mark A. de Belder, Kirk N. Garratt, Ioannis Iakovou, Hyo-Soo Kim, Young-Hak Kim, Guy LeClerc, Masato Nakamura, Massimo Napodano, Andrzej J. Ochala, Vincent J. Pompili 10:45 am - Quebec Heart and Lung Institute Quebec City, Canada 8:00 am - Spontaneous and Periprocedural Myocardial Infarctions: Definition, Ascertainment Alternatives (High-Sensitivity Troponins and Imaging), and Implications Harvey D. White 8:15 am - Periprocedural Hemorrhagic Complications and Mortality: Linkage or Causality? Frederick Feit 8:15 am - MitraClip Results in Degenerative and Functional Mitral Regurgitation: Identifying Appropriate Patients James B. Hermiller Jr Live Cases: Transcatheter Valve Therapies III Live Case Moderator: Ted Feldman Live Case Co-Moderator: Alec Vahanian Live Case Discussants: Vinay K. Bahl, Jorge A. Belardi, Raoul Bonan, Paul T.L. Chiam, Jan Harnek, Stamatios Lerakis, Francesco Maisano, Konstantinos Spargias, Pieter R. Stella 8:30 am - Quebec Heart and Lung Institute Quebec City, Canada 9:15 am - University Hospital Bonn Bonn, Germany 10:00 am - Discussion: What Have We Learned from These Cases? Chronic Limb Ischemia and Unusual Cases Moderator: Robert M. Schainfeld Co-Moderator: Tyrone J. Collins 10:15 am - The Role of Drug-Eluting Stents and Drug-Coated Balloons in Infrapopliteal Intervention Robert A. Lookstein 10:30 am - The “Holistic” Approach to Salvaging Tissue in Critical Limb Ischemia John R. Laird Jr 11:30 am - University Hospital Bonn Bonn, Germany Live Cases: Chronic Limb Ischemia and Unusual Cases 12:15 pm - Discussion: What Have We Learned from These Cases? Live Case Moderator: Robert M. Schainfeld Live Case Co-Moderator: Tyrone J. Collins Live Case Discussants: Rajesh M. Dave, Richard R. Heuser, Prakash Krishnan, Greg Mishkel, Alexander Nikanorov, Rahul S. Patel, Gary L. Schaer, Mehdi H. Shishehbor, James P. Zidar 12:30 pm - Adjourn Complex and Unusual Cases III Moderator: Jeffrey W. Moses Co-Moderator: Rajesh M. Dave 8:00 am - Mitral Regurgitation: Pathology, Pathophysiology, Natural History, and Surgical Therapies Alec Vahanian How to Treat Theater: Endovascular and Structural HEart Disease 8:00 am-12:30 Hall D pm - N o v e m b e r 1 1 , 2 0 11 12:50 pm - PROFI: A Prospective, Randomized Trial of Proximal Balloon Occlusion vs. Distal Filter Embolic Protection in Patients Undergoing Live Cases: Complex and Unusual Cases III Friday 12:40 pm - COBRA: A Prospective, Randomized Trial of Cryoplasty vs. Conventional Balloon Postdilatation of Nitinol Stents in the Superficial Femoral Artery of Patients with Diabetes Mellitus Subhash Banerjee T r a n s c at h e t e r Cardiovascular Therapeutics 10:45 am - Park Hospital Leipzig Leipzig, Germany 12:15 pm - Discussion: What Have We Learned from These Cases? 12:30 pm - Adjourn Transcatheter Valve Therapies III Moderator: Ted Feldman Co-Moderator: Alec Vahanian www.tctconference.com 139 Friday, November 11 Challenging Case Multiplex Challenging Case Theater 9:00 am-12:00 Hall D pm Aortic Intervention Moderators: J. Michael Bacharach, Jacques Busquet Discussants: Mirko Doss, Takao Ohki 9:00 am - Iatrogenic Aortic Dissection Benjamin Scott 9:12 am - Percutaneous Transcatheter Closure of Paravalvular Aortic Leak Piotr Pysz 9:24 am - Difficulties with a Horizontal Aortic Root Pak Hei Chan 9:36 am - Percutaneous Repair of an Aorta to Right Ventricular Fistula Bryan Cogar 9:48 am - Endovascular Revascularization of Bald Aortic Arch Sanjay Tyagi 11:24 am - Intraoperative Pulmonary Artery Stenting in Aortoarteritis: A Hybrid Procedure Kapil Rangan 11:36 am - Closure of Traumatic Muscular Interventricular Septal Defect Carlos Balestrini Moderators: Oscar A. Mendiz, Jamil Abdalla Saad Discussants: Alexandre Abizaid, Jorge Gaspar, Jose L. Leiva-Pons, Stephan Windecker 11:48 am - Transcatheter Closure of Perimembranous Ventricular Septal Defect Apostolos Tzikas 10:00 am - Case 1: An Unforgettable Coronary Complication, Saved Jorge Antonio Mayol Almera 12:00 pm - Adjourn 10:15 am - Case 2: An Unforgettable Peripheral Arterial Complication, Saved Alejandro O. Palacios International Society-Sponsored Case Theater 8:00 am-12:00 Hall D pm Complex and Unusual Issues in STEMI Intervention Sponsored by the Singapore Cardiac Society Moderators: Tian-Hai Koh, Swee Guan Teo Discussant: Charles Chan 8:00 am - Case 1: Left Main PCI During STEMI Aaron Wong 10:30 am - Case 3: An Unforgettable Interventional Congenital Heart Disease Complication, Saved Carlos Pedra 10:45 am - Case 4: An Unforgettable TAVR Complication, Saved Fabio S. Brito Management of Thrombus During PCI and STEMI Sponsored by the Italian Society of Invasive Cardiology 8:15 am - Case 2: A Complication During Primary PCI Adrian Low Moderator: Giulio Guagliumi Discussants: Bagrat Alekyan, David Antoniucci, Antonio L. Bartorelli 8:30 am - Case 3: IVUS Evaluation of the Infarct Site During STEMI Paul Ong 11:00 am - Case 1: Clinical Impact of Thrombus Composition in STEMI Massimo Fineschi 10:00 am - Challenging Pseudoaneurysm Closure Robert Huang 8:45 am - Case 4: What Can Go Wrong During PCI of a Branch Occlusion in STEMI? Chin Chee Tang 11:15 am - Case 2: Imaging Guidance for Thrombus Removal Francesco Saia 10:12 am - Management of a Ruptured Pseudoaneurysm of Transplanted Renal Artery Narenda N. Khanna Demanding and Unusual Noncoronary Cardiovascular Interventions Sponsored by the Mexican Society of Cardiology 11:30 am - Case 3: Manual and Mechanical Thrombus Aspiration: Tricks and Pitfalls Gennaro Sardella 10:24 am - Endovascular Treatment of Acute Critical Hand Ischemia Using a Novel Infusion Balloon Catheter Salman A. Arain Moderator: Jorge Gaspar Discussants: Jose Luis Assad Morel, Jose L. Leiva-Pons, Homero A. Ramirez, Alfredo Rodriguez 10:36 am - Endovascular Repair of a Large Thrombotic Carotid Pseudoaneurysm Narenda N. Khanna 9:00 am - Case 1: A Large Aortic Aneurysm After Stenting for Aortic Coarctation Guering Eidt-Lidt 10:48 am - Challenging Treatment of an Innominate Artery and Ostial Right Common Carotid Tarun Madan 9:15 am - Case 2: Challenges of Patent Ductus Arteriosus Closure in the Adult Patient Carlos Zabal Endovascular III Moderators: Luigi Salemme, Craig M. Walker Discussants: Alan Lumsden, Pedro Martinez-Clark Adult Congenital Heart Disease II Moderators: Eric Horlick, Michael J. Mullen Discussants: Phillip A. Horwitz, Lynn Peng 11:00 am - To Close or Not to Close an Atrial Septal Defect in Ischemic Cardiomyopathy Thomas Bartel 9:30 am - Case 3: Challenges of ASD Closure in the Adult Patient Jose Luis Lazaro Castillo 9:45 am - Case 4: The Endovascular Approach for the “Nutcracker Syndrome”—Surgery No Longer Needed? Jorge Gaspar 11:12 am - Complex Coiling of Remote Arteriovenous Malformations Matthew Bunte 140 My Worst Complication and My Best Save Sponsored by the Latin America Society of Interventional Cardiology program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s 11:45 am - Case 4: DES vs. Self-Expanding BMS When Thrombus is Present Davide Capodanno 12:00 pm - Adjourn Morning Spotlight Sessions Controversies in Interventional Cardiology: The Skeptic’s Corner 8:00 am-12:00 Room 104 pm Panel I. Interventional Cardiology and Surgery Crossroads Moderators: Sanjay Kaul, William W. O’Neill Discussants: Herbert D. Aronow, Mark W. Connolly, Luis A. Guzman, Michael A. Kutcher, Michel R. Le May, Jean-Claude Laborde, Robert E. Michler, Thomas A. Ports The World’s Premier Interventional Experience TCT2011 8:10 am - Discussion with Audience Q&A Commonly Held View II. Ad Hoc PCI Is Appropriate for Triple-Vessel Disease in Stable Angina 8:22 am - Contrarian Position: Europe Has it Right: All Patients Should Have an Informed Discussion Prior to PCI—Especially Those with Triple-Vessel Disease! Flavio L. Ribichini 8:32 am - Discussion with Audience Q&A Commonly Held View III. Mitral Regurgitation Is an Interventional Cardiology Disease 8:44 am - Contrarian Position: Interventional Devices Will Never Be Able to Manage the Spectrum of Mitral Pathology! David H. Adams 8:54 am - Discussion with Audience Q&A Commonly Held View VIII. FFR Should Be Required for PCI in Stable CAD 10:34 am - Contrarian Position: People Who Make These Statements Don’t Take Care of Patients—or Read the Literature Carefully! Jeffrey W. Moses 10:44 am - Discussion with Audience Q&A Commonly Held View IX. Dual Antiplatelet Therapy Should Be Continued for More Than Six Months After DES 10:56 am - Contrarian Position: Evidence-Based Nonsense! Fausto Feres 11:06 am - Discussion with Audience Q&A Commonly Held View X. CTA Should Be the Initial Screening Test for Coronary Artery Disease 11:18 am - Contrarian Position: Don’t Be Seduced by Pictures: Anatomy Is Less Critical Than Function and Perfusion! Leslee J. Shaw 11:28 am - Discussion with Audience Q&A Commonly Held View IV. TAVR for Aortic Stenosis Changes Everything 12:00 pm - Adjourn 9:06 am - Contrarian Position: More Strokes, Vascular Complications, Unknown Durability—Slow Down! D. Craig Miller Difficult Patients in Interventional Cardiology: The Art of Clinical Decision-Making 9:16 am - Discussion with Audience Q&A Commonly Held View V. Carotid Artery Stenting Is Standard of Care for Asymptomatic Carotid Artery Disease 9:28 am - Contrarian Position: CEA Reigns If Preventing Stroke Is Your Goal! Michael J. Reardon 9:38 am - Discussion with Audience Q&A Panel II. Interventional Cardiology Moderators: Eric R. Bates, Mark Reisman Discussants: Albert W. Chan, Donald Cutlip, Upendra Kaul, Michael A. Kutcher, Chaim S. Lotan, John A. Ormiston, Abhiram Prasad, Jonathan M. Tobis Commonly Held View VI. PFO Closure Has a Future 9:50 am - Contrarian Position: Time to Close the Book on PFO Closure! Darren L. Walters 8:00 am-12:05 Room 134 pm Clinical Decisions I. The “Poor Responder” to Clopidogrel Moderators: John A. McPherson, Shamir R. Mehta Discussants: Laurent Bonello, Somjot S. Brar, Paul A. Gurbel, Michelle O’Donoghue, Matthew J. Price, Dirk Sibbing, Tabassome Simon, Daniel I. Simon Point-Counterpoint 8:00 am - Pro: Point-of-Care Assays for Clopidogrel Responsiveness Offer Important Clinical Information and Should Be Used! Paul A. Gurbel 8:10 am - Con: Point-of-Care Assays for Clopidogrel Responsiveness Have Not Been Shown to be Useful and May Be Misleading! Daniel I. Simon 10:00 am - Discussion with Audience Q&A Commonly Held View VII. Bioabsorbable Stents Are the Future 10:12 am - Contrarian Position: Drug-Eluting Bioabsorbable Stents Will Introduce More Problems Than They Solve! Renu Virmani 8:20 am - Clinical Potential and Uses of Genetic Assays to Assess Responsiveness to Pharmacotherapy in Cardiology Michelle O’Donoghue 8:30 am - Case Presentation: A Patient with Successful PCI for Stable Angina with Clopidogrel Hyporesponsiveness Matthew J. Price 8:40 am - Discussion with Audience Q&A 8:55 am - Summary Comments: Clinical Decision-Making Today and Tomorrow John A. McPherson, Shamir R. Mehta Clinical Decisions II. The Angiographically Indeterminate Lesion: Using Adjunctive Imaging to Guide PCI Moderators: Alexandra J. Lansky, Alan C. Yeung Case Presenter: Jose M. de la Torre Hernandez Discussants: Jose de Ribamar Costa Jr, Michael Haude, Michael J. Lim, James K. Min, Gary S. Mintz, Szilard Voros, Gerald S. Werner - N o v e m b e r 1 1 , 2 0 11 8:00 am - Contrarian Position: CABG Provides More Durable Relief Than PCI and Is More Widely Applicable! Mark W. Connolly 10:22 am - Discussion with Audience Q&A Friday Commonly Held View I. Left Main PCI Will Make CABG Obsolete T r a n s c at h e t e r Cardiovascular Therapeutics 9:00 am - The Role of CT to Screen for and Assess Intermediate Lesions at Risk for Ischemia or Plaque Rupture Szilard Voros 9:08 am - Grayscale IVUS for Assessment of Indeterminate Lesions: When Is It Useful? Jose de Ribamar Costa Jr 9:16 am - The Emerging Role of VH-IVUS, OCT, and NIRS for Assessment of Indeterminate Lesions Gary S. Mintz 9:24 am - FFR for Assessment of Indeterminate Lesions: Strengths Yes, but Know the Limitations Gerald S. Werner 9:32 am - Case Presentation: Management of a Patient with Conflicting Clinical and Imaging/FFR Data Jose M. de la Torre Hernandez 9:42 am - Discussion with Audience Q&A 9:57 am - Summary Comments: Clinical Decision-Making Today and Tomorrow Alexandra J. Lansky, Alan C. Yeung Clinical Decisions III. Revascularization in Patients with Depressed Left Ventricular Function Moderators: Sanjay Kaul, Manish A. Parikh Discussants: John A. Bittl, Larry S. Dean, Vladimir Dzavik, Robert J. Freedman Jr, Norman E. Lepor, Mauro Moscucci, Richard Smalling, David X. Zhao Point-Counterpoint 10:02 am - There Is a Strong Rationale for Revascularization in Patients with Heart Failure (and Patients Benefit)! Richard Smalling www.tctconference.com 141 Friday, November 11 10:12 am - Don’t STICH Me! The Data for Revascularization in Patients with Depressed Ventricular Function is Weak! Sanjay Kaul 10:22 am - What Should Prompt Revascularization Decisions in Heart Failure: Ischemia, Viability, Symptoms, or Other? Vladimir Dzavik 10:32 am - Case Presentation: A Patient with Severe Heart Failure and Coronary Artery Disease Manish A. Parikh 10:42 am - Discussion with Audience Q&A 10:57 am - Summary Comments: Clinical Decision-Making Today and Tomorrow Sanjay Kaul, Manish A. Parikh Clinical Decisions IV. Contemporary Management of Stable Coronary Artery Disease Moderators: John S. Douglas Jr, Jeffrey W. Moses Discussants: David A. Cox, Allen Jeremias, David J. Maron, Binoy K. Singh, Rod H. Stables, Pim A.L. Tonino, Bonnie H. Weiner Point-Counterpoint 11:02 am - Position 1: Based on What We Know Today, Medical Therapy is Sufficient for Most Patients with Stable CAD! David J. Maron 11:12 am - Position 2: Functionally-Guided Revascularization Is the Best Way to Improve Symptoms and Potentially Save Lives! Pim A.L. Tonino 11:22 am - Position 3: Ultraconservatism Is Harming Patients: Follow the Evidence and Common Sense! Jeffrey W. Moses 11:32 am - Case Presentation: A Stable Symptomatic Patient with CAD Giora Weisz 11:42 am - Discussion with Audience Q&A 11:57 am - Summary Comments: Clinical Decision-Making Today and Tomorrow John S. Douglas Jr 12:05 pm - Adjourn TAVR Site Readiness: Organizing and Training Your Site to Prepare for TAVR 8:00 am-12:00 Room 135 pm Session I. Components of a Successful TAVR Program Moderators: Marian C. Hawkey, Mathew Williams Discussants: Joseph E. Bavaria, Michael Guiry, Sandra Lauck, Scott Lim, Kristen Skelton, E. Murat Tuzcu 8:00 am - The Heart Valve Team 1: Concept, Culture, and Commitment E. Murat Tuzcu 8:10 am - The Heart Valve Team 2: Physician and Nonphysician Contributors Sandra Lauck 8:20 am - Procedural Environment 1: A Dedicated Facility (Hybrid Room or Otherwise) Mathew Williams 8:30 am - Procedural Environment 2: Staffing, Stocking, Training, and Scheduling Michael Guiry 8:40 am - TAVR Site Qualification Standards: Recommended Site and Physician Expertise and Volume Requirements Kristen Skelton 8:52 am - Best Practice Guidelines for Managing TAVR Patients: Providing for Optimal Patient Care Before, During, and After TAVR is Essential! Scott Lim 9:04 am - Hospital Administration Must Be Onboard: Experiences and Suggestions Joseph E. Bavaria 9:14 am - Panel Discussion: Components of a TAVR Program Session II. The Critical First Step: Case Screening and Triaging to Optimal Therapies Moderators: Sandra Lauck, Scott Lim Discussants: Michael J. Davidson, Rebecca Tung Hahn, Jonathon A. Leipsic, Augusto D. Pichard, Nicolas van Mieghem, Mathew Williams 9:34 am - Organizing and Implementing a Multidisciplinary Valve Clinic Michael J. Davidson Advanced Noninvasive Imaging is a Must! 9:44 am - Basic Echo Requirements for TAVR Screening Rebecca Tung Hahn 9:54 am - Basic CTA Requirements for TAVR Screening Jonathon A. Leipsic 142 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s Case Distribution Expectations from a Busy TAVR Practice 10:04 am - Experiences from Washington Hospital Center Augusto D. Pichard 10:12 am - Experiences from Columbia University Medical Center Mathew Williams 10:20 am - Identifying High-Risk and Inoperable TAVR Patients: Risk Algorithms, Documentation, and Tips and Tricks Nicolas van Mieghem 10:32 am - Panel Discussion: Case Screening and Triaging for TAVR Session III. Managing Patients, Families, and Referring Physicians Moderators: Michael Guiry, Raj Makkar Discussants: Marian C. Hawkey, Martina Kelly Speight 10:47 am - How to Develop a Thriving TAVR Referral Practice: The West Coast Offense Raj Makkar 10:57 am - Communicating with Patients, Families, and Referring Physicians: Managing Expectations in Ultra-Sick AS Patients Martina Kelly Speight 11:07 am - Education and Training at All Levels Is Critical! This is a “New Ballgame” Marian C. Hawkey 11:17 am - Panel Discussion: TAVR Practice Building Session IV. Successful TAVR Models Moderators: Martina Kelly Speight, Augusto D. Pichard Discussants: Raoul Bonan, Ganesh Manoharan, E. Murat Tuzcu A Successful TAVR Organizational Model. . . . 11:27 am - From Europe Ganesh Manoharan 11:35 am - From Canada Raoul Bonan 11:43 am - From the United States E. Murat Tuzcu 11:51 am - Panel Discussion: Success Lessons from Around the World 12:00 pm - Adjourn The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Friday C a r d i o va s C u l a r researCh F o u n d at i o n - N o v e m b e r 1 1 , 2 0 11 Clinical Trials Center Experts in Protocol Design, Data Management, Core Laboratories, Indicated Judication and Regulatory Support Medical research is a continuum The Clinical Trials Center (CTC) sets the standard for conducting clinical research, that begins with a promising offering a full spectrum of interventional and pharmacological evaluations with concept and concludes with proving the safety and efficacy of a new therapy in a controlled clinical trial. CRF’s Clinical Trials Center provides comprehensive and complete trial design, evaluation, and analysis services. unmatched expertise. The CTC combines the comprehensive knowledge of leading physicians and technologists to streamline the research process from Phase I through Phase IV trials. The CTC provides the full spectrum of services needed for successful clinical research, including clinical and regulatory strategy, protocol and database development, statistical analysis, safety surveillance, and core laboratory capabilities. This full portfolio of abilities means our clients can have a tailored research plan that meets their needs. Visit us at the Partnership Pavilion on the first floor of Moscone North. www.tctconference.com 143 C A R D I O VA S C U L A R RESEARCH F O U N D AT I O N Center for Education Improving Patient Outcomes Through Worldwide Medical Programming For more information, contact: STRATEGIC PLANNING · MEETING LOGISTICS Johnnie White, CMP PROGRAM DEVELOPMENT · FACULTY MANAGEMENT Executive Director, Meetings and Educational Services Tel: 646-434-4392 POST-MEETING RECONCILIATION ·MARKETING AND BRANDING E-mail: [email protected] GRAPHIC DESIGN · WEB SITE DEVELOPMENT Lisa Hathaway Stella VIDEO AND INTERACTIVE MEDIA · E-LEARNING Director, Industry Relations Tel: 646-434-4343 E-mail: [email protected] CRF is certified to accredit programs for continuing medical education (CME). Visit us at the Partnership Pavilion on the first floor of Moscone North. The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Evening Programs.................................................................................... 146 Tuesday, November 8 Breakfast Meetings.................................................................................. 147 Presentation Theater South...................................................................... 150 Evening Programs.................................................................................... 150 Wednesday, November 9 Breakfast Meetings.................................................................................. 152 Presentation Theater North...................................................................... 155 Presentation Theater South...................................................................... 156 Evening Programs.................................................................................... 156 Thursday, November 10 Breakfast Meetings.................................................................................. 157 Presentation Theater North...................................................................... 160 Presentation Theater South...................................................................... 161 Evening Programs.................................................................................... 161 Friday, November 11 Breakfast Meetings.................................................................................. 162 Satellites Monday, November 7 the Moscone Center · san francisco, ca November 7-11, 2011 Satellite Symposia Monday, November 7 EARCH · F N Massimo Napodano, MD Padova University Hospital Padova, Italy Matthew T. Roe, MD, MHS Duke Clinical Research Institute Durham, NC CULAR · R O AS ES ARDIO · C V Evening Programs Ran Kornowski, MD Rabin Medical Center Petach Tikva, Israel UN D AT I O Knights of the Roundtable 2011: Defending and Challenging AMI Therapies Hilton San Francisco, Imperial Ballroom/ Franciscan Room Sponsored by Cardiovascular Research Foundation Supported through educational grants from Abbott Vascular, AstraZeneca, Medtronic CardioVascular, and TherOx, Inc. (as of October 1, 2011) This activity has been approved for AMA PRA Category 1 Credit™ Dietmar Trenk, PhD Herz-Zentrum Bad Krozingen Bad Krozingen, Germany Bernhard Witzenbichler, MD Charite University Medicine Berlin Campus Benjamin Franklin Berlin, Germany Stephen D. Wiviott, MD Brigham and Women’s Hospital Boston, MA Agenda 7:00 pm - Dinner Reception Chairs Bernard J. Gersh, MB, ChB, DPhil Mayo Clinic Rochester, MN Cindy L. Grines, MD William Beaumont Hospital Royal Oak, MI Gregg W. Stone, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Faculty Eric R. Bates, MD University of Michigan Medical Center Ann Arbor, MI Bruce R. Brodie, MD Moses Cone Heart and Vascular Center Greensboro, NC David A. Cox, MD Lehigh Valley Hospital Bethlehem, PA Jan-Henk E. Dambrink, MD, PhD Isala Klinieken Zwolle, The Netherlands Anthony H. Gershlick, MD University of Leicester Leicester, United Kingdom Sanjay Kaul, MD Cedars-Sinai Medical Center Los Angeles, CA Should Clopidogrel, Ticagrelor, or Prasugrel Be Used in Most Cases of Primary PCI (and Is Preloading Important)? Moderator: Cindy L. Grines Discussants: Eric R. Bates, Anthony H. Gershlick, Sanjay Kaul, Ajay J. Kirtane, Matthew T. Roe, Gregg W. Stone, Dietmar Trenk, Stephen D. Wiviott 8:00 pm - Case Presenter Dietmar Trenk 8:10 pm - Opinionated Position Statement Stephen D. Wiviott 8:18 pm - Roundtable Discussion Panel When Should Thrombectomy Be Performed During Primary PCI and How? Moderator: Gregg W. Stone Discussants: Bruce R. Brodie, David A. Cox, Jan-Henk E. Dambrink, Cindy L. Grines, Ajay J. Kirtane, Ran Kornowski, Massimo Napodano, Bernhard Witzenbichler 8:30 pm - Case Presenter Bernard J. Gersh 8:40 pm - Opinionated Position Statement Massimo Napodano 8:48 pm - Roundtable Discussion Panel Ajay J. Kirtane, MD, SM NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY 146 program · T r a n s c a t h ete r C a r d i o v a s c u l a r T h e r a pe u tic s When Should Multivessel Revascularization Be Performed During Primary PCI? Moderator: Bernard J. Gersh Discussants: Eric R. Bates, Bruce R. Brodie, David A. Cox, Anthony H. Gershlick, Sanjay Kaul, Ran Kornowski, Massimo Napodano, Dietmar Trenk 9:00 pm - Case Presenter Ran Kornowski 9:10 pm - Opinionated Position Statement Cindy L. Grines 9:18 pm - Roundtable Discussion Panel Should Patients with STEMI Presenting 12 to 48 Hours After Symptom Onset Be Emergently Revascularized? Moderator: Gregg W. Stone Discussants: Eric R. Bates, Jan-Henk E. Dambrink, Bernard J. Gersh, Anthony H. Gershlick, Cindy L. Grines, Sanjay Kaul, Matthew T. Roe, Bernhard Witzenbichler 9:30 pm - Case Presenter Jan-Henk E. Dambrink 9:40 pm - Opinionated Position Statement Eric R. Bates 9:48 pm - Roundtable Discussion Panel 10:00 pm - Adjourn Innovation in the Management and Treatment of Vascular Disease: 2012 and Beyond Hilton San Francisco, Grand Ballroom A Sponsored by Covidien Chair Michael R. Jaff, DO Massachusetts General Hospital Boston, MA Faculty Joseph Broderick, MD University of Cincinnati Cincinnati, OH Senator Bill Frist, MD Nashville, TN James D. Joye, DO El Camino Hospital Mountain View, CA John R. Laird Jr, MD UC Davis Medical Center Sacramento, CA Mark A. Turco, MD Chief Medical Officer, Covidien Vascular Therapies Takoma Park, MD The World’s Premier Interventional Experience TCT2011 Agenda 7:00 pm - Dinner Reception 7:00 pm - Dinner Reception 8:00 pm - Introduction, Covidien Vascular Therapies Mark A. Turco Overview of the Elixir Medical Programs 8:10 pm - Keynote: An Insider’s Crystal Ball Look into Health Reform: Trends That Impact Innovation Senator Bill Frist 8:00 pm - Drug-Eluting Stents with Durable (DESyne™) and Biodegradable (DESyne™ BD) Polymers 8:07 pm - Drug-Eluting Bioresorbable Scaffold (DESolve™) 8:30 pm - Antirestenosis Therapies: The Changing PAD Landscape John R. Laird Jr 8:15 pm - DESyne™ Randomized Clinical Trial Two-Year Results Venous Vascular 8:25 pm - DESyne™ BD Randomized Clinical Trial Primary Endpoint Results 8:45 pm - Into the Blue: Endovenous Intervention James D. Joye 8:35 pm - IVUS Insights with DESyne™ and DESyne™ BD Neurovascular 9:00 pm - Acute Stroke Intervention: Data and Trends Joseph Broderick 9:15 pm - Q&A Session Panel 9:30 pm - Adjourn Chairs Alexandre Abizaid, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Martin B. Leon, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Faculty Peter Fitzgerald, MD, PhD Stanford University Hospital Palo Alto, CA John A. Ormiston, MB, ChB Auckland City Hospital Auckland, New Zealand Stefan Verheye, MD, PhD ZNA Middleheim Hospital Antwerp, Belgium Agenda 7:00 pm - Dinner Reception 8:00 pm - Welcome and Introductions Alan B. Lumsden 8:05 pm - Building the Room: A Business Case Alan B. Lumsden 8:15 pm - Visit to the Hybrid Room Alan B. Lumsden DESolve™ Bioresorbable Scaffold 8:20 pm - Hybrid Aortic Cases Michael J. Reardon 8:45 pm - Preclinical Experience with the DESolve™ Bioresorbable Scaffold 8:30 pm - Hybrid Coronary Cases Mahesh K. Ramchandani 8:55 pm - Clinical Experience with the DESolve™ FIM Study 8:40 pm - Hybrid Ablation Procedures Basel Ramlawi 9:05 pm - DESolve™ Nx Clinical Trial 8:50 pm - Percutaneous Aortic Valves: If I Knew Then What I Know Now Neal S. Kleiman Discussion 9:15 pm - Take-Home Message Innovating Vascular Restoration: Clinical Experience with Elixir’s Durable and Biodegradable Polymer DES, and Bioresorbable Scaffold Platforms Hilton San Francisco, Continental Ballroom 6-9 Sponsored by Elixir Medical Michael J. Reardon, MD Methodist DeBakey Heart and Vascular Center Houston, TX 9:30 pm - Adjourn - N o v e m b e r 7 - 11 , 2 0 11 Peripheral Vascular Clinical Experience with the DESyne™ and DESyne™ BD Novolimus-Eluting DES Basel Ramlawi, MD Methodist DeBakey Heart and Vascular Center Houston, TX Satellite Symposia Agenda T r a n s c at h e t e r Cardiovascular Therapeutics 9:00 pm - Advanced Imaging and Navigation Alan B. Lumsden 9:10 pm - Discussion with Audience Q&A 9:30 pm - Adjourn Hybrid Room Design and Utilization: Lessons Learned Hilton San Francisco, Continental Ballroom 1-4 Sponsored by Methodist DeBakey Heart and Vascular Center Supported through an educational grant from The Methodist Hospital This activity has been approved for AMA PRA Category 1 Credit™ Chairs Neal S. Kleiman, MD Methodist DeBakey Heart and Vascular Center Houston, TX Tuesday, November 8 Breakfast Meetings Optimizing PCI Outcomes in Complex Patients: Role of Pharmacology and Hemodynamic Support The Moscone Center, Room 112 Sponsored by ABIOMED Inc. and The Medicines Company Chair George D. Dangas, MD, PhD Mount Sinai Medical Center New York, NY Alan B. Lumsden, MD Methodist DeBakey Heart and Vascular Center Houston, TX Faculty Faculty William W. O’Neill, MD University of Miami Miami, FL Mahesh K. Ramchandani, MD Methodist DeBakey Heart and Vascular Center Houston, TX Neal S. Kleiman, MD Methodist DeBakey Heart and Vascular Center Houston, TX www . tctc o n f e r ence . c o m 147 Satellite Symposia ES EARCH · F O ARDIO · C V CULAR · R N N ARDIO · C V CULAR · R Acute Kidney Injury: Effect of Contrast Media—Does It Really Matter? The Moscone Center, Room 113 Sponsored by Cardiovascular Research Foundation 8:00 am - Adjourn AS AS EARCH · F 7:45 am - Discussion with Audience Q&A Panel 8:00 am - Adjourn ES 7:30 am - Lessons from PROTECT-II: Role of Hemodynamic Support with Impella and Complex Case Review William W. O’Neill 7:50 am - Q&A Session Panel O 7:15 am - Assessing the Risk and Targeting the Pharmacologic Treatment: The Role of Direct Thrombin Inhibitors George D. Dangas 7:35 am - Discussion: Impact of TAVR in Your Center and “Unique” Aspects of the Western United States Panel D AT I 7:00 am - Understanding the Management Challenges of the Complex Patient Undergoing PCI Neal S. Kleiman 7:25 am - Site Readiness: Top 10 General Requirements to Be a Successful Heart Team Gregory P. Fontana UN 6:30 am - Breakfast O Agenda Supported through an educational grant from Guerbet UN D AT I O Preparing for a Transcatheter AVR Program and Heart Valve Team in Your Center: The Nuts and Bolts (Western United States) The Moscone Center, Room 123 Sponsored by Cardiovascular Research Foundation Supported through an educational grant from Edwards Lifesciences This activity has been approved for AMA PRA Category 1 Credit™ This activity has been approved for AMA PRA Category 1 Credit™ Praveen Mehrotra, MD Massachusetts General Hospital Boston, MA Tomokuki Suzuki, MD Sakakibara Heart Institute Tokyo, Japan Lorraine Choi, MD UTMB Galveston, TX Richard Solomon, MD University of Vermont Burlington, VT Agenda 6:30 am - Breakfast 7:00 am - Welcome and Introductions Mathew Williams Agenda 7:03 am - Percutaneous Extraction of Pacing Leads from the Left Coronary Artery and Left Ventricle Sammy Elmariah, Praveen Mehrotra 6:30 am - Breakfast 7:18 am - Q&A and Discussion 7:00 am - Tutorial on Contrast Media Richard Solomon 7:22 am - Successful Recanalization of Left Coronary Artery Dissection Involved with Type A Acute Aortic Dissection Tomokuki Suzuki, Yusuke Watanabe 7:10 am - Acute Kidney Injury: Prevention and Risks Somjot S. Brar 7:37 am - Q&A and Discussion 7:05 am - Takeaway Lessons from the PARTNER Trial D. Craig Miller 7:20 am - Contrast-Induced Nephropathy: Does the Type of Contrast Media Matter? One-Year Outcomes of the ICON Study Usman Baber 7:41 am - Aortocaval Fistula: A Case of Rapidly Deteriorating Course, Diagnosis, and Endovascular Treatment Lorraine Choi, Gilani Syed 7:15 am - Review of Balloon-Expandable TAVR Technology, Procedural Tips, and the “Special” Role of the Heart Team Raj Makkar 7:30 am - Case Presentation with Q&A Somjot S. Brar Moderator: Roxana Mehran Discussants: Usman Baber, Richard Solomon 7:56 am - Q&A and Discussion 8:00 am - Adjourn 148 Sammy Elmariah, MD Massachusetts General Hospital Boston, MA Faculty Faculty 7:00 am - Welcome and Introductions Raj Makkar scholarship winners Gilani Syed, MD UTMB Galveston, TX Somjot S. Brar, MD Kaiser Permanente Los Angeles, CA 6:30 am - Breakfast Mathew Williams, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Roxana Mehran, MD Mount Sinai Medical Center New York, NY Raj Makkar, MD Cedars-Sinai Medical Center Los Angeles, CA Agenda Chair Chair Chair D. Craig Miller, MD Stanford University Medical School Stanford, CA Supported through an educational grant from Medtronic CardioVascular Yusuke Watanabe, MD Institut Cardiovasculaire Paris Sud Paris, France Usman Baber, MD Mount Sinai Medical Center New York, NY Gregory P. Fontana, MD Cedars-Sinai Medical Center Los Angeles, CA Innovative Hybrid Therapy for Treatment of Complex Cardiovascular Lesions: Collaborative Care Case Reviews The Moscone Center, Room 122 Sponsored by Cardiovascular Research Foundation program · T r a n s c a t h ete r C a r d i o v a s c u l a r T h e r a pe u tic s 8:00 am - Adjourn The World’s Premier Interventional Experience TCT2011 Chair Martin B. Leon, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Faculty Antonio Colombo, MD Columbus Hospital/San Raffaele Hospital Milan, Italy Agenda 6:30 am - Breakfast 7:00 am - Introduction and Objectives Martin B. Leon 7:05 am - Cre8 Polymer-Free DES Features and Preclinical Results Alexandre Abizaid 7:20 am - Cre8 Polymer-Free DES Clinical Plan Antonio Colombo 7:35 am - Discussion Moderator: Martin B. Leon Discussants: Alexandre Abizaid, Antonio Colombo 7:50 am - Take-Home Messages Martin B. Leon 8:00 am - Adjourn 3-D-Guided Interventions for Structural Heart and Complex PCI Procedures The Moscone Center, Room 124 Sponsored by GE Healthcare Faculty Jeffrey W. Moses, MD NewYork-Presbyterian Hospital/ Weill Cornell Medical Centerr New York, NY Ashok Tirouvanziam, MD University Hospital of Nantes Nantes, France Alan Yeung, MD Stanford University School of Medicine Palo Alto, CA Agenda 6:30 am - Breakfast 7:00 am - Transcatheter Valve Implantation: 3-D Rendering to Guide Valve Replacement Ashok Tirouvanziam Moderator: Jeffrey W. Moses Juan F. Granada, MD The Jack H. Skirball Center for Cardiovascular Research New York, NY 7:50 am - Adjourn Sander IJsselmuiden, MD Dordrecht Dordrecht, The Netherlands PCI Optimization with FFR and OCT The Moscone Center, Room 111 Sponsored by St. Jude Medical Alan Yeung, MD Stanford University Stanford, CA Chair Agenda Marco A. Costa, MD, PhD University Hospitals, Case Western Reserve University Cleveland, OH 6:30 am - Breakfast Faculty Bernard De Bruyne, MD, PhD Cardiovascular Center Aalst Aalst, Belgium Agenda 6:30 am - Breakfast 7:00 am - FFR and OCT to Determine PCI Appropriateness Marco A. Costa 7:10 am - OCT: Clinical Updates and Case Presentations Marco A. Costa 7:25 am - FFR: Clinical Updates and Case Presentations Bernard De Bruyne 7:45 am - Q&A Session Moderator: Marco A. Costa Discussant: Bernard De Bruyne 8:00 am - Adjourn Solving the Sizing Dilemma Using a Self-Apposing Stent: STEMI Clinical Program in Europe and the United States The Moscone Center, Room 121 Sponsored by STENTYS S.A. Chairs Maurice Buchbinder, MD Foundation for Cardiovascular Medicine La Jolla, CA Roxana Mehran, MD Mount Sinai Medical Center New York, NY Faculty Don Cutlip, MD Harvard Clinical Research Institute Cambridge, MA Peter Fitzgerald, MD Stanford University Stanford, CA 7:00 am - Introduction Maurice Buchbinder 7:02 am - Self-Apposing Technology: From Product Design to Imaging-Based Evidence Peter Fitzgerald 7:12 am - One-Year Clinical Results in STEMI: APPOSITION I and II Sander IJsselmuiden - N o v e m b e r 7 - 11 , 2 0 11 Alexandre Abizaid, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil 7:25 am - Imaging in Complex Coronary Artery Interventions Alan Yeung Moderator: Jeffrey W. Moses Satellite Symposia Future DES Technology, Today: Cre8 The Moscone Center, Room 125 Sponsored by CID SpA T r a n s c at h e t e r Cardiovascular Therapeutics 7:20 am - Ongoing and Future Clinical Evaluations: APPOSITION III and IV TBA 7:30 am - US Clinical Trial and IDE: Strawman Protocol of the APPOSITION V Study Don Cutlip 7:40 am - Discussion Panel 8:00 am - Adjourn A Paradigm Shift In Bifurcations: Tryton Experience in the United States and Europe The Moscone Center, Room 120 Sponsored by Tryton Medical, Inc. Chairs William F. Fearon, MD Cardiovascular Medicine Clinic Stanford, CA Thierry Lefèvre, MD Institut Cardiovasculaire Paris Sud Massy, France Faculty Yaron Almagor, MD Jesselson Heart Center Jerusalem, Israel Antonio Bartorelli, MD Centro Cardiologico Monzino, Italy David Foley, MD Beaumont Hospital Dublin, Ireland Maciej Lesiak, MD University Hospital Poznan, Poland www . tctc o n f e r ence . c o m 149 Satellite Symposia 7:23 am - IVUS Assessment In Bifurcations and Case Review Antonio Bartorelli 7:32 am - Long-term Experience: The Dublin Series David Foley 7:41 am - Left Main Treatment: A New Era? Maciej Lesiak 7:50 am - Discussion and Conclusion Moderators: William F. Fearon, Thierry Lefèvre 8:00 am - Adjourn Treating the Complex Lesion: Techniques and Technology for Left Mains and Bifurcations The Moscone Center, Room 114 Sponsored by Volcano Corporation Chairs Saibal Kar, MD Cedars-Sinai Medical Center Los Angeles, CA Brian Whisenant, MD Intermountain Medical Center Salt Lake City, UT Faculty Shephal Doshi, MD Pacific Heart Institute Santa Monica, CA David Muller, MD St. Vincent’s Hospital Darlinghurst, Australia Vivek Reddy, MD Mount Sinai Medical Center New York, NY Chair Agenda David Rizik, MD Scottsdale Healthcare Phoenix, AZ 12:30 pm - LAA Occlusion in the Treatment of Atrial Fibrillation: An Electrophysiologist’s Perspective Vivek Reddy Agenda 6:30 am - Breakfast 7:00 am - Welcome and Introductions David Rizik 7:05 am - Bifurcation Strategies and Techniques 7:20 am - Side Branch Options and the Role of FFR 7:35 am - Left Main PCI: Assessment and Approaches 7:50 am - Discussion with Audience Q&A 8:00 am - Adjourn ARDIO · C V CULAR · R N O 7:14 am - Tryton Clinical Data Overview and Real-World Cases Yaron Almagor AS EARCH · F 7:05 am - The Tryton IDE Study: A First in Man in the United States William F. Fearon Controversies in LAA Occlusion as a Treatment for A-Fib Patients The Moscone Center Presentation Theater South, Santa Rosa Valley (Located in the Exhibit Hall) Sponsored by Coherex, Inc. ES 7:00 am - Introduction Thierry Lefèvre Evening Programs D AT I Lunchtime Sessions UN Presentation Theater South 6:30 am - Breakfast O Agenda Drug-Coated Balloons: An Emerging Breakthrough Technology Hilton San Francisco, Continental Ballroom 6-9 Sponsored by Cardiovascular Research Foundation Supported through educational grants from Abbott Vascular, Boston Scientific Corporation, Cook Medical, Lutonix, MEDRAD Interventional, Medtronic CardioVascular (as of October 1, 2011) This activity has been approved for AMA PRA Category 1 Credit™ Chairs Juan F. Granada, MD The Jack H. Skirball Center for Cardiovascular Research Orangeburg, NY William A. Gray, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Gregg W. Stone, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Faculty 12:40 pm - The “Novel Anticoagulants:” A Reality Check Brian Whisenant Gary M. Ansel, MD Riverside Methodist Hospital Columbus, OH 12:50 pm - Imaging Techniques for LAA Closure Saibal Kar Antonio Colombo, MD Columbus Hospital/San Raffaele Hospital Milan, Italy 1:00 pm - What LAA Closure Might Look Like in a Busy EP Practice Shephal Doshi Andrew Farb, MD US Food and Drug Administration Silver Spring, MD 1:10 pm - Coherex WaveCrest Case Summary with 45-Day Follow-up David Muller Dierk Scheinert, MD Park-Krankenhaus Leipzig, Germany 1:20 pm - Q&A Discussion Panel Bruno Scheller, MD University of Saarland Homburg, Germany 1:30 pm - Adjourn Pieter R. Stella, MD, PhD Department of Heart and Lungs Utrecht, The Netherlands Renu Virmani, MD CVPath Institute, Inc. Gaithersburg, MD 150 program · T r a n s c a t h ete r C a r d i o v a s c u l a r T h e r a pe u tic s The World’s Premier Interventional Experience TCT2011 8:45 pm - Impact of Coating Formulation and Antiproliferative Choices on Drug Transfer and Tissue Pharmacokinetics Bruno Scheller 8:55 pm - Discussion Panel 9:00 pm - Regulatory Challenges to DCB Development and Validation in the United States Andrew Farb 9:10 pm - Discussion Panel 9:15 pm - Tissue Safety Studies: Similarities and Critical Differences Between DCB and DES Technologies Renu Virmani 9:25 pm - Discussion Panel 9:30 pm - Clinical Trial Design for DCB Above and Below the Knee: What Are the Endpoints and Challenges to Completion? Gary M. Ansel 9:40 pm - Discussion Panel 9:45 pm - Future Generation DCB Platforms Juan F. Granada 9:55 pm - Discussion Panel 10:00 pm - Adjourn ARDIO · C V N O 8:40 pm - Discussion Panel D AT I 8:30 pm - Similarities and Differences in Today’s DCB Technologies William A. Gray UN 8:25 pm - Discussion Panel TAVR Has Arrived: Pillars of Success Hilton San Francisco, Grand Ballroom AB Sponsored by Cardiovascular Research Foundation Supported through an educational grant from Edwards Lifesciences This activity has been approved for AMA PRA Category 1 Credit™ Chairs Martin B. Leon, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Craig R. Smith, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Faculty Joseph E. Bavaria, MD University of Pennsylvania Philadelphia, PA Alain G. Cribier, MD Hôpital Charles Nicolle Rouen, France Todd M. Dewey, MD Medical City Dallas Dallas, TX Howard C. Herrmann, MD Hospital of the University of Pennsylvania Philadelphia, PA Samir R. Kapadia, MD The Cleveland Clinic Foundation Cleveland, OH Dean J. Kereiakes, MD The Christ Hospital Cincinnati, OH Scott Lim, MD UVA Medical Center Charlottesville, VA Michael J. Mack, MD The Heart Hospital Baylor Plano Plano, TX D. Craig Miller, MD Stanford University Medical School Stanford, CA William W. O’Neill, MD University of Miami Miami, FL Augusto D. Pichard, MD Washington Hospital Center Washington, DC Allan Schwartz, MD Columbia University Medical Center New York, NY Paul S. Teirstein, MD Scripps Clinic and Research Foundation La Jolla, CA Martyn R. Thomas, MD St Thomas’ Hospital London, United Kingdom Vinod H. Thourani, MD Emory University Hospital Midtown Atlanta, GA E. Murat Tuzcu, MD The Cleveland Clinic Foundation Cleveland, OH Alec Vahanian, MD Hôpital Bichat Paris, France Thomas Walther, MD Kerckhoff Klinik Bad Nauheim Bad Nauheim, Germany - N o v e m b e r 7 - 11 , 2 0 11 8:15 pm - The Potential for Peripheral DCBs: Why Aren’t Other Therapeutic Alternatives (ie, DES) Sufficient? Dierk Scheinert O 8:10 pm - Discussion Panel CULAR · R EARCH · F 8:00 pm - The Potential for Coronary DrugCoated Balloons (DCBs): Indications, Opportunities, and Challenges Gregg W. Stone AS ES 7:00 pm - Dinner Reception Satellite Symposia Agenda T r a n s c at h e t e r Cardiovascular Therapeutics Olaf Wendler, MD, PhD King’s College Hospital London, United Kingdom Mathew Williams, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Agenda 7:00 pm - Dinner Reception INTRODUCTION Martin B. Leon, Craig R. Smith PART I. APPROPRIATE CASE SELECTION 8:00 pm - Choosing the Best Patients for TAVR: Today and Tomorrow Michael J. Mack 8:15 pm - Panel Discussion: TAVR Case Selection and Considerations Moderators: Martin B. Leon, Craig R. Smith Discussants: Scott Lim, Michael J. Mack, D. Craig Miller, William W. O’Neill, Allan Schwartz, Alec Vahanian PART II. THE HEART TEAM aND SITE READINESS 8:30 pm - Forming a Heart Team and Preparing Your Site for Success: Not “Business as Usual” E. Murat Tuzcu 8:45 pm - Panel Discussion: Evolving the Heart Team Concept Moderators: Martin B. Leon, Craig R. Smith Discussants: Joseph E. Bavaria, Alain G. Cribier, Todd M. Dewey, Howard C. Herrmann, Dean J. Kereiakes, E. Murat Tuzcu, Olaf Wendler www . tctc o n f e r ence . c o m 151 Satellite Symposia PART III. OPTIMIZING CLINICAL OUTCOMES 9:00 pm - Best TAVR Practice Standards Today and Future Expectations Martyn R. Thomas 9:15 pm - Panel Discussion: Best Clinical Practices and Future Enhancements Moderators: Martin B. Leon, Craig R. Smith Discussants: Samir R. Kapadia, Augusto D. Pichard, Paul S. Teirstein, Martyn R. Thomas, Vinod H. Thourani, Thomas Walther, Mathew Williams 9:30 pm - Adjourn Emerging Paradigms and New Frontiers in Science and Application of Antithrombotic Interventions for High-Risk ACS Hilton San Francisco, Continental Ballroom 1-4 Sponsored by University of Massachusetts Medical School Supported through an educational grant from sanofi-aventis 8:40 pm - Radial vs. Femoral Access for PCI in the Setting of NSTE-ACS: Implications for Anticoagulation Management—Does Mode of Access Matter? Sunil V. Rao 9:05 pm - Novel Anticoagulants for High-Risk ACS: Rationale and Study Designs Focused on the Safety and Efficacy of Factor Xa Inhibition in the Setting of NSTE-ACS David P. Faxon 9:30 pm - TCT Director Keynote Address: Contemporary and Evolving Approaches to Optimizing Outcomes in High-Risk ACS: A Near Future Vision Statement Focused on Advances in Anticoagulation Gregg W. Stone 9:50 pm - Chair’s Summary on the Future of Anticoagulation for High-Risk ACS in the Setting of PCI Deepak L. Bhatt 10:00 pm - Adjourn Wednesday, November 9 Breakfast Meetings This activity has been approved for AMA PRA Category 1 Credit™ Faculty David P. Faxon, MD Harvard Medical School Boston, MA Ron Waksman, MD Cardiovascular Research Institute Washington, DC Stephan Windecker, MD Swiss Cardiovascular Center Bern Bern, Switzerland Agenda 6:30 am - Breakfast 7:00 am - Welcome and Opening Remarks Ron Waksman 7:05 am - Relevance of Vascular Healing in DES with Bioabsorbable vs. Permanent Polymers Michael Joner 7:20 am - Clinical Utility of a Bioabsorbable Polymer on a Modern Stent Platform with Hybrid Coating Stephan Windecker 7:30 am - Overview of Clinical Experience with a DEB Releasing Paclitaxel from a BTHC Excipient Ralph Toelg 7:40 am - Lessons Learned about a Bioabsorbable Metallic Scaffold: Update from the BIOSOLVE-I Trial Michael Haude Chair Deepak L. Bhatt, MD Harvard Medical School Boston, MA Ralph Toelg, MD Herz-Kreislauf-Zentrum Bad Segeberg, Germany Management of Complex Patients: How the Recent Data May Affect our Approach to Patients The Moscone Center, Room 111 Supported through an educational grant from ABIOMED, Inc. 7:50 am - Closing Remarks Panel 8:00 am - Adjourn Sunil V. Rao, MD Duke University Medical Center Durham, NC This activity has been approved for AMA PRA Category 1 Credit™ Treating Chronic Total Occlusions: Advanced Technology and Techniques The Moscone Center, Room 132 Sponsored by Boston Scientific Agenda Faculty Gregg W. Stone, MD Columbia University Medical School New York, NY Please visit www.tctconference.com for the latest agenda. Tony Das, MD Presbyterian Heart Institute Dallas, TX Agenda Nonpermanent Vascular Therapies: Are They the Future of Vascular Intervention? The Moscone Center, Room 123 Sponsored by BIOTRONIK Dierk Scheinert, MD Heart Center Leipzig Leipzig, Germany Faculty 7:00 am - The Landscape of Tools and Techniques for Crossing Difficult Lesions Tony Das 7:00 pm - Dinner Reception 8:00 pm - Emerging Strategies for Optimizing Outcomes in High-Risk ACS: Look at Where We’ve Been and What the Frontier Looks Like—From Anticoagulation to Stent Selection Deepak L. Bhatt 8:15 pm - The Evolution of AnticoagulationBased Interventions in PCI: From UFH and LMWH to Direct Thrombin and Factor Xa Inhibition—What Have the Trials Taught Us? Where Will the New Breakthroughs Come? Deepak L. Bhatt Michael Haude, MD Lukaskrankenhaus Neuss Neuss, Germany Michael Joner, MD Deutsches Herzzentrum München München, Germany Agenda 6:30 am - Breakfast 7:25 am - TruePath™ CTO Device: The Next Frontier for Intraluminal Crossing Dierk Scheinert 7:50 am - Q&A Session Panel 8:00 am - Adjourn 152 program · T r a n s c a t h ete r C a r d i o v a s c u l a r T h e r a pe u tic s The World’s Premier Interventional Experience CULAR · R O N EARCH · F UN D AT I O Preparing for a Transcatheter AVR Program and Heart Valve Team in Your Center: The Nuts and Bolts (Midwestern United States) The Moscone Center, Room 130 Sponsored by Cardiovascular Research Foundation Supported through an educational grant from Edwards Lifesciences Chair Lars G. Svensson, MD, PhD Cleveland Clinic Foundation Cleveland, OH Faculty Todd M. Dewey, MD Medical City Dallas Hospital Dallas, TX Samir Kapadia, MD Cleveland Clinic Foundation Cleveland, OH Agenda 6:30 am - Breakfast 7:00 am - Welcome and Introductions Lars G. Svensson 7:05 am - Takeaway Lessons from the PARTNER Trial Lars G. Svensson 7:15 am - Review of Balloon Expandable TAVR Technology, Procedural Tips and the “Special” Role of the Heart Team Samir Kapadia 7:25 am - Site Readiness: Top 10 General Requirements to Be a Successful Heart Team Todd M. Dewey 7:35 am - Discussion: Impact of TAVR in Your Center and “Unique” Aspects of the Midwestern United States Panel The Emergence of Peripheral Drug-Coated Balloons The Moscone Center, Room 112 Sponsored by Lutonix, Inc. Chair Gary Ansel, MD Riverside Hospital Columbus, OH Gregg W. Stone, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Faculty Alexandre Abizaid, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Antonio Colombo, MD Columbus Hospital/San Raffaele Hospital Milan, Italy Dariusz Dudek, MD, PhD Jagiellonian University Krakow, Poland Eberhard Grube, MD University Hospital Bonn Bonn, Germany Chaim S. Lotan, MD Hadassah University Hospital Jerusalem, Israel Federico Piscione, MD, PhD University of Naples Federico II Naples, Italy Ashok Seth, MD, PhD Escorts Heart Institute and Research Centre New Delhi, India Sigmund Silber, MD Heart Center at the Isar Munich, Germany Agenda 6:30 am - Breakfast 7:00 am - Unmet Needs, MGuard, and the MASTER Trial Gregg W. Stone Moderator: Chaim S. Lotan 7:15 am - MGuard in Acute MI: Three-Year Follow-up Federico Piscione 7:50 am - Q&A Session Panel 7:25 am - MGuard for Complex Lesions Antonio Colombo 8:00 am - Adjourn 7:35 am - Challenging MGuard Cases TBA 7:55 am - Take-Home Messages Gregg W. Stone 8:00 am - Adjourn Chair Faculty Juan F. Granada, MD The Jack H. Skirball Center for Cardiovascular Research New York, NY D. Christopher Metzger, MD Wellmont CVA Heart Institute Kingsport, TN Dierk Scheinert, MD Heart Center Leipzig/Park Hospital Leipzig, Germany Renu Virmani, MD CVPath Institute, Inc. Gaithersburg, MD - N o v e m b e r 7 - 11 , 2 0 11 This activity has been approved for AMA PRA Category 1 Credit™ Thrombus Management in STEMI with MGuard Micro-Mesh Technology: Complex Lesions and the MASTER Trial The Moscone Center, Room 124 Sponsored by InspireMD Satellite Symposia AS ES ARDIO · C V TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Agenda 6:30 am - Breakfast 7:00 am - Introduction Gary Ansel 7:05 am - The Perceived Paradox of DrugCoated Balloons (DCB) Juan F. Granada 7:17 am - DCB Insights from the Preclinical Model Renu Virmani 7:32 am - The Moxy™ Drug-Coated Balloon and the LEVANT 2 Trial D. Christopher Metzger 7:42 am - Technique and Procedure Lessons from DCB Clinical Trials Dierk Scheinert 8:00 am - Adjourn Management of Thrombus in STEMI Interventions: Discussion and Debate on the Role of AngioJet Thrombectomy and Manual Aspiration The Moscone Center, Room 122 Sponsored by MEDRAD Interventional Faculty David Antoniucci, MD Careggi Hospital Florence, Italy Bruce R. Brodie, MD Moses Cone Heart and Vascular Center Greensboro, NC www . tctc o n f e r ence . c o m 153 Satellite Symposia Giuseppe De Luca, MD, PhD Eastern Piedmont University Novara, Italy Georgios Sianos, MD, PhD AHEPA University Hospital Thessaloniki, Greece Agenda 6:30 am - Breakfast 7:00 am - Introduction and Overview of Aspiration and Mechanical Thrombectomy Trials and STEMI Guidelines Bruce R. Brodie 7:10 am - Importance and Classification of Coronary Thrombus Burden Georgios Sianos 7:20 am - JETSTENT and SMART PCI Trials: Impact on STEMI Interventions David Antoniucci 7:30 am - Updated Meta-analysis on Thrombectomy in STEMI Giuseppe De Luca 7:25 am - Left Main Case Panel 7:40 am - A Complex Bifurcation Case Panel 7:55 am - Conclusion and Take-Home Messages Panel 8:00 am - Adjourn Advanced Imaging for TAVR The Moscone Center, Room 113 Sponsored by Paieon Inc. Chair Martin B. Leon, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Faculty 7:40 am - Discussion and Debate: AngioJet or Aspiration or Dual Strategy? Panel Peter Block, MD Emory University Atlanta, GA 8:00 am - Adjourn Gregory P. Fontana, MD Cedars-Sinai Medical Center Los Angeles, CA Bifurcation Lesion Treatment Dilemmas: Solutions with the Experts The Moscone Center, Room 121 Sponsored by MINVASYS Chairs Alexandre Abizaid, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Roxana Mehran, MD Mount Sinai Medical Center New York, NY Faculty Jacques Berland, MD Clinique Saint Hilaire Rouen, France Bruno Garcia Del Blanco, MD Hospital Vall d'Hebron Barcelona, Spain Azeem Latib, MD San Raffaele Hospital Milan, Italy Agenda 6:30 am - Breakfast 7:00 am - Introduction Panel 7:05 am - Provisional Approach Technique: Step by Step Panel 154 7:10 am - A True Bifurcation Case Panel program · Howard C. Herrmann, MD Penn Heart and Vascular Center Philadelphia, PA Ran Kornowski, MD Rabin Medical Center Petach Tikva, Israel Raj Makarr, MD Cedars-Sinai Medical Center Los Angeles, CA Mathew Williams, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Agenda 6:30 am - Breakfast 7:00 am - Welcome Panel 7:03 am - Valve-in-Valve for Severe AR After TAVR Howard C. Herrmann Moderator: Martin B. Leon 7:21 am - Edwards SAPIEN Valve Positioning During Transcatheter Aortic Valve Implantation: Multicenter Evaluation with Clinical and Anatomical Correlates Ran Kornowski Moderator: Martin B. Leon T r a n s c a t h ete r C a r d i o v a s c u l a r T h e r a pe u tic s 7:39 am - TAVR Postdeployment Analysis Mathew Williams Moderator: Martin B. Leon 7:57 am - Closing Panel 8:00 am - Adjourn Coronary Laser Atherectomy in the 21st Century The Moscone Center, Room 114 Sponsored by Spectranetics Chair On Topaz, MD Charles George Veterans Affairs Medical Center Asheville, NC Faculty Luc Bilodeau, MD Royal Victoria Hospital Montreal, Quebec Arthur Lee, MD Kaiser Permanente Santa Clara, CA Antonis Pratsos, MD Bryn Mawr Hospital Philadelphia, PA Agenda 6:30 am - Breakfast 7:00 am - Excimer Laser: Correlation Between Basic Science and Clinical Utilization On Topaz 7:12 am - Integrating Laser Atherectomy into Today’s Environment of Complex PCI Arthur Lee 7:24 am - Use of Excimer Laser for Complex and Uncrossable Lesions Luc Bilodeau 7:36 am - Current Experience and Challenging Cases Antonis Pratsos 7:48 am - Q&A Session Panel 8:00 am - Adjourn Advanced Tools and Techniques for Challenging Lower Extremity Revascularizations The Moscone Center, Room 125 Sponsored by Terumo Medical Corporation Chairs Nelson Lim Bernardo, MD Washington Cardiology Center Washington, DC The World’s Premier Interventional Experience TCT2011 7:55 am - Questions from the Audience and Closing Remarks Carlo Di Mario Agenda 8:00 am - Adjourn 6:30 am - Breakfast 7:00 am - Welcome Presentation Theater North Lunchtime Sessions 7:05 am - Femoro-Popliteal Arterial Occlusive Disease 7:30 am - Below-the-Knee Arterial Occlusive Disease 8:00 am - Adjourn Guide Extension: Making Impossible Cases Possible and Difficult Cases Easier The Moscone Center, Room 120 Sponsored by Vascular Solutions, Inc. Chair Carlo Di Mario, MD, PhD Royal Brompton Hospital London, United Kingdom Alexandre Abizaid, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Faculty Pawel E. Buszman, MD American Heart of Poland Katowice, Poland Faculty Douglas G. Fraser, MD Manchester Heart Centre Manchester, United Kingdom Sameer I. Dani, MD Apollo Hospital International Ltd. Ahmedabad, India J. Aaron Grantham, MD Mid America Heart Institute Kansas City, MO Upendra Kaul, MD Escorts Heart Institute and Research Centre New Delhi, India William L. Lombardi, MD North Cascade Cardiology Bellingham, WA Martin B. Leon, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Agenda 6:30 am - Breakfast 7:00 am - Welcome and Introductions Carlo Di Mario 1:08 pm - Future of DES: A Call for MitsuMerilimus-Eluting Coronary Stent Martin B. Leon 1:16 pm - Floor Discussion 1:21 pm - Adjourn Chair Ricardo Costa, MD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Aravinda Nanjundappa, MD Charleston Area Medical Center Charleston, WV 1:00 pm - Complex Cases with BioMime Upendra Kaul Ashok Seth, DSc Escorts Heart Institute and Research Centre New Delhi, India Wojciech Wojakowski, MD, PhD Third Division of Cardiology Katowice, Poland Agenda Atrial Fibrillation and Uncontrolled Hypertension: What Interventional Cardiologists Need to Know The Moscone Center, Presentation Theater North, Sonoma Valley (Located in Hall D) Sponsored by The Society for Cardiovascular Angiography and Interventions - N o v e m b e r 7 - 11 , 2 0 11 7:55 am - Q&A Discussion Panel A Decade of Stent Design: DES Evolution The Moscone Center, Presentation Theater North, Napa Valley (Located in Hall D) Sponsored by Meril Life Sciences Pvt. Ltd. 12:52 pm - meriT-2 Extension in Brazil: A Deep Look into BioMime Behavior - IVUS, OCT, and Endothelial Function Tests Ricardo Costa Satellite Symposia Jihad Mustapha, MD West Michigan Heart Grand Rapids, MI T r a n s c at h e t e r Cardiovascular Therapeutics Supported through an educational grant from Abbott Vascular, ABIOMED, AstraZeneca, Boston Scientific, Daiichi Sankyo Lilly, Medtronic, and Merck This activity has been approved for AMA PRA Category 1 Credit™ Chairs Alaide Chieffo, MD San Raffaele Hospital Milan, Italy Roxana Mehran, MD Mount Sinai Hospital New York, NY Faculty Deepak L. Bhatt, MD, MPH VA Boston Healthcare System and Brigham and Women's Hospital Boston, MA 7:05 am - History of Guide Extension and Principles of Action Douglas G. Fraser 12:15 pm - Evolution of Novel DES Technologies: An Introduction Alexandre Abizaid David Holmes, MD Mayo Clinic Rochester, MN 7:15 am - Guide Extension Utility for Stent Delivery Carlo Di Mario 12:20 pm - Polish Clinical Experience with Novel Hybrid Stent Design: NexGen Pawel E. Buszman Henry Krum, MD Monash University Melbourne, Australia 7:25 am - CTO Uses of Guide Extension William L. Lombardi 12:28 pm - Complex Cases with NexGen Wojciech Wojakowski 7:35 am - Guide Extension in Retrograde Vein Graft PCI J. Aaron Grantham 12:36 pm - meriT-1 Final Angiographic Analysis and >18 Months of Follow-up Sameer I. Dani Julinda Mehilli, MD Deutsches Herzzentrum Munich, Germany 7:45 am - Guide Extension Benefit in Peripheral Interventions Aravinda Nanjundappa 12:44 pm - meriT-2 BioMime in Complex Patients Ashok Seth A. Sonia Petronio, MD University of Pisa Pisa, Italy Vivek Y. Reddy, MD Mount Sinai Medical Center New York, NY www . tctc o n f e r ence . c o m 155 Satellite Symposia Agenda 12:15 pm - Introduction Roxana Mehran 12:20 pm - Case 1: Patient with Pulmonary Edema and Uncontrolled Hypertension Julinda Mehilli 12:30 pm - Renal Artery Stenting: In Whom and When? Deepak L. Bhatt 12:35 pm - Renal Artery Denervation: In Whom and When? Henry Krum 12:40 pm - Panel Discussion Moderator: Alaide Chieffo 12:45 pm - Case 2: Patient with Recurrent Atrial Fibrillation A. Sonia Petronio 12:55 pm - Pharmacotherapy and Ablation Therapy: Which and Why? Vivek Reddy 1:00 pm - LAA Occlusion: When and Why? David Holmes 1:05 pm - Panel Discussion Moderator: Roxana Mehran 1:10 pm - Adjourn Presentation Theater South Lunchtime Sessions 12:30 pm - How Does OCT Help Understand Plaque Progression and Changes Following DES Placement? Masataka Nakano Bifurcation Case Reviews: 12:45 pm - Clinical Lessons from OCT Takagi Akasaka 8:45 pm - Case 2: Do Angle and Anatomy Influence Outcomes in Bifurcation Stenting? Achim Buettner 1:00 pm - Q&A Session Renu Virmani 1:15 pm - Adjourn Evening Programs Reducing Late Stent Thrombosis: Does BA9™ Technology Benefit Your Patients Long-term? Hilton San Francisco Dinner Reception (7:00 pm-8:00 pm): Franciscan Room Evening Program (8:00 pm-9:35 pm): Imperial Ballroom Sponsored by Biosensors International Chair Stephan Windecker, MD Inselspital Bern Bern, Switzerland Jacques Berland, MD Clinique Saint Hilaire Rouen, France Faculty OCT: Comparisons to Histology The Moscone Center Presentation Theater South, Santa Rosa Valley (Located in the Exhibit Hall) Sponsored by St. Jude Medical Alexandre Abizaid, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Faculty Achim Buettner, MD Herz-Zentrum Bad Krozingen, Germany Takagi Akasaka, MD Wakayama Medical University Wakayama, Japan Aloke V. Finn, MD Emory University Hospital Midtown Atlanta, GA Masataka Nakano, MD CVPath Institute, Inc. Gaithersburg, MD Renu Virmani, MD CVPath Institute, Inc. Gaithersburg, MD 12:15 pm - Course Welcome, Overview, and Objectives Renu Virmani 12:16 pm - ACS: Plaque Morphology and Progression Aloke V. Finn program · Keith G. Oldroyd, MD West of Scotland Regional Heart and Lung Center Glasgow, Scotland 8:55 pm - Where Dedicated Bifurcation Stents Can Benefit Your Patients: Axxess™: The Self-Expanding Bifurcation Biolimus A9-Eluting Stent Alexandre Abizaid 9:10 pm - Discussion Panel 9:25 pm - Take-Home Message Jacques Berland 9:35 pm - Adjourn Navigating the Evolving Opportunities for the Interventional Cardiologist Hilton San Francisco, Grand Ballroom AB Sponsored by Boston Scientific Chair Ted Feldman, MD NorthShore University Health System, NorthShore Cardiology Skokie, IL Faculty Keith Dawkins, MD Boston Scientific Natick, MA Saibal Kar, MD Cedars-Sinai Medical Center Los Angeles, CA Ian T. Meredith, MBBS, PhD Monash Heart Southern Health Clayton, Australia Chesley (Sully) B. Sullenberger III Pilot, US Airways Flight 1549 Danville, CA Agenda Agenda 7:00 pm - Dinner Reception 7:00 pm - Dinner Reception 8:00 pm - Embracing the Future Lancscape of Interventional Medicine Keith Dawkins Moderator: Ted Feldman 8:00 pm - Welcome and Opening Remarks Stephan Windecker 8:05 pm - The Impact of Patient and Lesion Complexity on Long-term Clinical Outcomes Antonio L. Bartorelli Agenda 156 Antonio L. Bartorelli, MD University of Milan Milan, Italy 8:35 pm - Case 1: Is There Still a Role for Provisional Stenting? Keith G. Oldroyd 8:20 pm - Very Long-term Outcomes with Biolimus A9 from an All-Comers Randomized Clinical Trial: LEADERS Four-Year Data Stephan Windecker T r a n s c a t h ete r C a r d i o v a s c u l a r T h e r a pe u tic s 8:10 pm - Left Atrial Appendage Closure in Patients with Atrial Fibrillation Saibal Kar Moderator: Ted Feldman 8:25 pm - The Future of Transcatheter Aortic Valve Replacement Ian T. Meredith Moderator: Ted Feldman The World’s Premier Interventional Experience CULAR · R N Faculty Philip B. Adamson, MD Oklahoma Heart Hospital Oklahoma City, OK O William T. Abraham, MD Ohio State University Columbus, OH D AT I Chair Optimal Antiplatelet Therapy in Patients Undergoing PCI: A Case-Based Roundtable with the Experts Hilton San Francisco, Continental Ballroom 1-4 Sponsored by Cardiovascular Research Foundation Supported through an educational grant from AstraZeneca This activity has been approved for AMA PRA Category 1 Credit™ Chairs Clinical Cases: Management Dilemmas 8:50 pm - Case 1: Complex Coronary Case with Multiple Stents George D. Dangas 8:57 pm - Case 2: Post-PCI Patient with Bleeding David J. Moliterno Deepak L. Bhatt, MD VA Boston Healthcare System, Brigham and Women’s Hospital, and Harvard Medical School Boston, MA 9:05 pm - Expert Panel Case Discussion Moderator: Roxana Mehran Discussants: Deepak L. Bhatt, George D. Dangas, Paul A. Gurbel, Stefan K. James, David J. Moliterno, Matthew J. Price Roxana Mehran, MD Mount Sinai Medical Center New York, NY 9:25 pm - Words of Wisdom: The Five Important Points to Take Home Stefan K. James Faculty 9:30 pm - Adjourn David E. Kandzari, MD Piedmont Heart Institute Atlanta, GA George D. Dangas, MD, PhD Mount Sinai Medical Center New York, NY Warren L. Strickland, MD Huntsville Hospital Huntsville, AL Paul A. Gurbel, MD Sinai Hospital of Baltimore System Baltimore, MD Breakfast Meetings Stefan K. James, MD Uppsala Clinical Research Center Uppsala, Sweden Management of Complex Patients, Expanding Your Practice: Latest Technologies, Applications and CostEffectiveness Considerations The Moscone Center, Room 130 Sponsored by ABIOMED, Inc Agenda 7:00 pm - Dinner Reception 8:00 pm - Current Methods and Limitations of Assessing the Development of Acute Decompensated Heart Failure Philip B. Adamson 8:20 pm - CHAMPION Trial Results William T. Abraham 8:40 pm - Potential Benefits and Value of Pressure-Guided Hemodynamic Management Warren L. Strickland 9:00 pm - Integration of this New Technology into Today’s Cardiology Practice David E. Kandzari 9:30 pm - Adjourn David J. Moliterno, MD University of Kentucky Lexington, KY Matthew J. Price, MD Scripps Clinic La Jolla, CA Thursday, November 10 Chair Agenda George W. Vetrovec, MD VCU Medical Center Richmond, VA 7:00 pm - Dinner Reception Faculty 8:00 pm - Welcome Roxana Mehran Brij Maini, MD Pinnacle Health and Vascular Institute Harrisburg, PA 8:05 pm - Recommendations for DAPT in PCI Patients: A Mini-Review of ACC/AHA/ESC PCI Guidelines Deepak L. Bhatt 8:12 pm - The Pharmacodynamic Platform for Improved Antiplatelet Regimens: Is There Any Role of Platelet Inhibition Assessment and Genetic Testing? Paul A. Gurbel 8:20 pm - The Landscape of Antiplatelet Agents: Which Drug for Whom? Roxana Mehran - N o v e m b e r 7 - 11 , 2 0 11 Prevention of Heart Failure Hospitalizations with Wireless, Implantable Pulmonary Artery Pressure Monitoring Hilton San Francisco, Continental Ballroom 6-9 Sponsored by CardioMEMs UN 9:30 pm - Adjourn O 9:20 pm - Q&A Session Moderator: Ted Feldman EARCH · F 8:50 pm - Leading Through Change Chesley (Sully) B. Sullenberger III Moderator: Ted Feldman 8:35 pm - Discussion Topic: Why Choose One Drug Over Another (Safety, Efficacy, or Cost)? Moderator: Deepak L. Bhatt Discussants: George D. Dangas, Paul A. Gurbel, Stefan K. James, Roxana Mehran, David J. Moliterno, Matthew J. Price Satellite Symposia AS ES 8:40 pm - Considerations for the Interventionalist as We Look to the Future Ted Feldman ARDIO · C V TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics Srihari S. Naidu, MD Winthrop University Hospital Mineola, NY Agenda 6:30 am - Breakfast 7:00 am - The Emerging Field of Percutaneous Circulatory Support: How It May Change Our Practice George W. Vetrovec www . tctc o n f e r ence . c o m 157 Satellite Symposia 7:30 am - Emerging Clinical Applications of Hemodynamic Support: Case Reviews Srihari S. Naidu Ashish Pershad, MD Heart and Vascular Center of Arizona Phoenix, AZ 7:40 am - Cost-Effectiveness of Revascularization in High-Risk Patients Undergoing PCI with Impella Brij Maini Michael Wyman, MD Torrance Memorial Medical Center Torrance, CA Agenda 6:30 am - Breakfast 7:00 am - Are Stents as Good as We Think? Outcomes in Challenging PCI Subsets Louis Cannon 8:00 am - Adjourn New Era in CTO PCI: The Hybrid Approach and BridgePoint Medical The Moscone Center, Room 114 Sponsored by BridgePoint Medical Chairs Aaron Grantham, MD Saint Luke’s Mid America Heart and Vascular Institute Kansas City, MO William Lombardi, MD PeaceHealth St. Joseph Medical Center Bellingham, WA Craig Thompson, MD Yale University School of Medicine New Haven, CT Faculty Tony DeMartini, MD Springfield Memorial Hospital Springfield, IL 158 program · 7:35 am - Q&A Session Panel 7:50 am - Q&A Session Panel 7:40 am - Antegrade Dissection Re-entry: Tips and Tricks to Improve Success and Procedural Efficiency Ashish Pershad Moderator: William Lombardi 8:00 am - Adjourn 7:55 am - Q&A Session Panel 8:00 am - Adjourn AS CULAR · R EARCH · F 7:50 am - Q&A Session Moderator: Louis Cannon 7:15 am - Review of Balloon Expandable TAVR Technology, Procedural Tips and the “Special” Role of the Heart Team Augusto D. Pichard 7:35 am - Discussion: Impact of TAVR in Your Center and “Unique” Aspects of the Eastern United States Panel ES 7:25 am - New Clinical Research on Bioabsorbable Drug Delivery: Perspectives from the EVOLVE Clinical Trial Program Ian T. Meredith 7:05 am - Takeaway Lessons from the PARTNER Trial Howard C. Herrmann 7:20 am - Hybrid Approach: A New Algorithm for Treating CTOs Michael Wyman Moderator: Aaron Grantham ARDIO · C V Ian T. Meredith, MBBS, PhD Monash Heart Southern Health Clayton, Australia 7:00 am - Welcome and Introductions Augusto D. Pichard 7:15 am - Q&A Session Panel N Louis Cannon, MD Michigan Heart and Vascular Specialists Petoskey, MI 6:30 am - Breakfast 7:25 am - Site Readiness: Top 10 General Requirements to Be a Successful Heart Team Joseph E. Bavaria O Chairs 7:00 am - Broadening the Antegrade Approach: When You Can’t or Don’t Want to Go Retrograde Tony DeMartini Moderator: Craig Thompson D AT I Lessons from New Data in Coronary Stenting The Moscone Center, Room 124 Sponsored by Boston Scientific 6:30 am - Breakfast UN 8:00 am - Adjourn Agenda O 7:55 am - Q&A Session Panel Agenda Preparing for a Transcatheter AVR Program and Heart Valve Team in Your Center: The Nuts and Bolts (Eastern United States) The Moscone Center, Room 132 Sponsored by Cardiovascular Research Foundation Supported through an educational grant from Edwards Lifesciences This activity has been approved for AMA PRA Category 1 Credit™ Chair Augusto D. Pichard, MD Washington Hospital Center Washington, DC Faculty Joseph E. Bavaria, MD University of Pennsylvania Philadelphia, PA Howard C. Herrmann, MD University of Pennsylvania Philadelphia, PA T r a n s c a t h ete r C a r d i o v a s c u l a r T h e r a pe u tic s Robotic-Assisted PCI: User Experience in Daily Practice The Moscone Center, Room 112 Sponsored by Corindus Vascular Robotics and Philips Healthcare Chairs Joseph Carrozza, MD Steward St. Elizabeth’s Medical Center Boston, MA Peter Fitzgerald, MD Stanford University Medical Center Stanford, CA Faculty Ronald Caputo, MD SJH Cardiology Associates Liverpool, NY D. Christopher Metzger, MD Wellmont CVA Heart Institute Kingsport, TN Jeffrey W. Moses, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Giora Weisz, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Agenda 6:30 am - Breakfast 7:00 am - Opening Remarks Moderators: Joseph Carrozza, Peter Fitzgerald The World’s Premier Interventional Experience TCT2011 Faculty Faculty Jorge Gaspar, MD Mexico City, Mexico 7:10 am - High-Volume Operator Experience with Robotic-Assisted PCI D. Christopher Metzger Ian Menown, MD Craigavon, Ireland Michaël Angioi, MD University Hospital Nancy Nancy, France 7:18 am - How Cardiovascular Robotics Is Changing PCI Jeffrey W. Moses 7:34 am - Beyond PCI: Robotics for Structural Heart Disease Procedures Peter Fitzgerald 7:42 am - Q&A Session Moderator: Joseph Carrozza 8:00 am - Adjourn The Identification and Treatment of Venous Insufficiency: A New Frontier for Cardiology Practices The Moscone Center, Room 111 Sponsored by Covidien Vascular Therapies Chairs James D. Joye, DO El Camino Hospital Mountain View, CA Paul H. Kramer, MD Liberty Cardiovascular Specialists Liberty, MO Agenda 6:30 am - Breakfast 7:00 am - Identification of Venous Insufficiency: Disease State James D. Joye, Paul H. Kramer 7:15 am - Treatment of Venous Insufficiency: RF Ablation James D. Joye, Paul H. Kramer Karl-Ludwig Schulte, MD Berlin, Germany Agenda Antonio Serra, MD Barcelona, Spain 7:00 am - Five-Year Follow-up After Percutaneous Coronary Intervention with Titanium-Nitride-Oxide-Coated Stents vs. Paclitaxel-Eluting Stents in Acute Myocardial Infarction: The TITAX AMI Trial Petri Tuomainen Agenda 6:30 am - Breakfast 7:00 am - Welcome and Introduction Sigmund Silber 7:02 am - Part 1: Are DEB an Option for Diabetic Patients? DEAR: Results of the Argentinean Experience Alfredo Rodriguez 7:12 am - Part 2: Are DEB an Option for Diabetic Patients? Valentines Trial I: Update on Subgroups Sigmund Silber 7:22 am - Experiences with DIOR® DEB in the National Institute of Cardiology (Mexico City) Jorge Gaspar 7:29 am - Periphery, First Experiences, and Colombian Results, Announcement of Activation and First Results of Randomized Studies Karl-Ludwig Schulte 7:36 am - Part 1: Are DEB an Option for De Novo Lesions? Focus on DEB Plus CoCr-Stent (MAGICAL™) Mohd Ali Rosli 7:43 am - Part 2: Are DEB an Option for De Novo Lesions? Focus on DEB Only (Valentines Trial II) Ian Menown 7:30 am - Future Technologies and Innovations in the Treatment of Venous Insufficiency James D. Joye, Paul H. Kramer 7:50 am - Part 3: Are DEB an Option for De Novo Lesions? Focus on DEB in Small Vessels (Spanish Multicenter Registry) Antonio Serra 7:45 am - Q&A Session Panel 8:00 am - Adjourn 8:00 am - Adjourn Petri Tuomainen, MD Kuopio Hospital Kuopio, Finland 6:30 am - Breakfast 7:15 am - A Randomized Comparison Of Titan2 BAS With Xience V EES in Acute Coronary Syndrome Patients: The BASEACS Trial 18-Month Follow-up Pasi Karjalainen 7:30 am - Coronary Angioplasty with the Titan2 Bio Active Stent in Acute Myocardial Infarction Patients: The CATS-AMI Large Scale Registry Michaël Angioi 7:45 am - Optical Coherence Tomography (OCT) Findings After Titan2 and Xience V Stents Implantations After 18 Months of Follow-up: The BASE-OCT Trial Pasi Karjalainen 8:00 am - Adjourn True Vessel Characterization: Implications for Increasing Stenting Safety and Preventing Coronary Events The Moscone Center, Room 122 Sponsored by InfraReDx, Inc Chair James A. Goldstein, MD William Beaumont Hospital Royal Oak, MI Faculty Patrick W. Serruys, MD, PhD Erasmus Medical Center Rotterdam, NL New Frontiers in DEB Technologies The Moscone Center, Room 125 Sponsored by Eurocor GmbH Titanium-Nitride-Oxide Bio Active Stent Technology: The Evidence-Based Medicine to Fight Restenosis Safely Over Time The Moscone Center, Room 113 Sponsored by Hexacath Gregg W. Stone, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Chairs Chair 6:30 am - Breakfast Mohd Ali Rosli, MD Kuala Lumpur, Malaysia Pasi Karjalainen, MD Satakunta Central Hospital Pori, Finland 7:00 am - Introduction and Symposium: Learning Objectives James A. Goldstein Sigmund Silber, MD, PhD Munich, Germany - N o v e m b e r 7 - 11 , 2 0 11 7:26 am - Integrating the CorPath 200 System into the Cath Lab Workflow Ronald Caputo Alfredo Rodriguez, MD Buenos Aires, Argentina Satellite Symposia 7:02 am - Overview of the CorPath 200 System and the PRECISE Trial Giora Weisz T r a n s c at h e t e r Cardiovascular Therapeutics Agenda www . tctc o n f e r ence . c o m 159 Satellite Symposia 7:05 am - Optimizing PCI Outcomes Through Multimodality Imaging (Integrated IVUS, OCT, and/or NIR Spectroscopy) Patrick W. Serruys Faculty Agenda Michael Haude, MD Lukaskrankenhaus Neuss Neuss, Germany 6:30 am - Breakfast 7:20 am - Optimizing PCI Outcomes: Detection of Lesions at Risk for Distal Embolization Complications James A. Goldstein Mitchell W. Krucoff, MD Duke University Medical Center Durham, NC 7:05 am - Overcoming Barriers to FFR Daily Use - Is It Possible to Obtain Adenosine Free FFR? Morton J. Kern 7:35 am - Detection of Vulnerable Plaques: Are We Close to Clinical Applicability? Gregg W. Stone 7:45 am - Q&A Session 8:00 am - Adjourn STEMI: Door to Balloon or Door to Device? The Moscone Center, Room 121 Sponsored by MAQUET Cardiovascular Ulf Landmesser, MD University Hospital Zurich Zürich, Switzerland Steven W.L. Lee, MD The University of Hong Kong Queen Mary Hospital, Hong Kong Roxana Mehran, MD Mount Sinai Medical Center New York, NY Agenda 6:30 am - Breakfast Chair Ralph Brindis, MD University of San Francisco Medical Center San Francisco, CA 7:00 am - Introduction to a New Category of Stents Martin B. Leon 7:05 am - Why Our Patients Need It Roxana Mehran Faculty Eric R. Bates, MD University of Michigan Health System Ann Arbor, MI Dorian L. Beasley, MD Indiana University Health Cardiovascular Center Indianapolis, IN Manesh R. Patel, MD Duke University Medical Center Durham, NC Richard W. Smalling, MD Memorial Hermann Heart and Vascular Institute, University of Texas Houston, TX Agenda Please visit www.tctconference.com for the latest agenda. The New Combo Dual Therapy Stent The Moscone Center, Room 120 Sponsored by OrbusNeich Alexandre Abizaid, MD, PhD Instituto Dante Pazzanese de Cardiologia São Paulo, Brazil Martin B. Leon, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY 7:15 am - Randomized REMEDEE Study Design Michael Haude 7:30 am - Pro-healing Stent Coverage Assessment by OCT Steven W.L. Lee 7:45 am - Ongoing and Planned Clinical Investigations Discussants: Mitchell W. Krucoff, Ulf Landmesser 7:50 am - Adjourn Breaking Down Barriers to FFR Adoption: Introducing iFR, a Vasodilator Independent Measure of Fractional Flow Reserve The Moscone Center, Room 123 Sponsored by Volcano Corporation Morton J. Kern, MD University of California Irvine Orange, CA Faculty Justin Davies, MD, PhD Imperial College London, United Kingdom Javier Escaned, MD, PhD Hospital Clínico San Carlos Madrid, Spain 160 program · 7:20 am - Introduction to iFR, a New Pressure-Derived Vasodilator Free Measure of Fractional Flow Reserve Justin Davies 7:40 am - The Future of FFR and the Functional Management of your Patients Javier Escaned 7:50 am - Closing Comments and Audience Q&A Morton J. Kern 8:00 am - Adjourn Presentation Theater North Lunchtime Sessions 7:10 am - The Technology Behind the Combo Dual Therapy Stent Alexandre Abizaid Chair Chairs 7:00 am - Welcome and Introduction Morton J. Kern T r a n s c a t h ete r C a r d i o v a s c u l a r T h e r a pe u tic s The Future of the Cath Lab: Managing Complexity for Improved Safety and Outcomes in CTO, TAVI, and Carotid Intervention The Moscone Center, Presentation Theater North, Sonoma Valley (Located in Hall D) Sponsored by Cardiovascular Learning Network, a NACCME Initiative Supported through an educational grant from ACIST Medical Systems This activity has been approved for AMA PRA Category 1 Credit™ Approved for 1 AMA PRA Category 1 Credit, 1.0 Contact Hour for Nurses, and 1 ARRT Category A CE Credit Chair Roxana Mehran, MD Mount Sinai Medical Center New York, NY Faculty John R. Laird Jr, MD UC Davis Medical Center Sacramento, CA Jeffrey W. Moses, MD NewYork-Presbyterian Hospital/ Weill Cornell Medical Center New York, NY The World’s Premier Interventional Experience TCT2011 12:15 pm - Case Review Gerry Wilkins 8:18 pm - Importance of Ischemia Pre- and Post-Revascularization Leslee J. Shaw 12:30 pm - Q&A Discussion Panel 8:30 pm - Discussion Panel 12:45 pm - Case Review Adrian Low 8:33 pm - Importance of Complete Revascularization Bernard J. Gersh 1:00 pm - Q&A Discussion Panel 1:15 pm - Adjourn Yujie Zhou, MD Beijing An Zhen Hospital Beijing, China ARDIO · C V N O Ian T. Meredith, MBBS, PhD Monash Medical Center Victoria, Australia Supported through an educational grant from Gilead Sciences This activity has been approved for AMA PRA Category 1 Credit™ Chair Giora Weisz, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Faculty Jeroen J. Bax, MD Leiden University Medical Center Leiden, The Netherlands Faculty Bernard J. Gersh, MB, ChB, DPhil Mayo Clinic Rochester, MN Guosheng Fu, MD Sir Run Run Shaw Hospital Hangzhou, China Leslee J. Shaw, PhD Emory University School of Medicine Atlanta, GA Yangsoo Jang, MD Yonsei University College of Medicine Seoul, South Korea Gregg W. Stone, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Adrian Low, MD National University Hospital of Singapore Singapore 9:00 pm - Discussion Panel 9:03 pm - Management of Patients with Incomplete Revascularization Giora Weisz 9:15 pm - Discussion Panel 9:30 pm - Adjourn AS CULAR · R EARCH · F Chairs Ischemia, Viability, and Complete Revascularization in CAD: What Really Matters? Hilton San Francisco, Continental Ballroom Sponsored by Cardiovascular Research Foundation 8:48 pm - Vulnerable Plaque: The Wild Card Factor Gregg W. Stone ES Complex PCI: Asia-Pacific Approaches The Moscone Center, Presentation Theater South, Santa Rosa Valley (Located in the Exhibit Hall) Sponsored by Medtronic D AT I Lunchtime Sessions UN Presentation Theater South CULAR · R O Please visit www.tctconference.com for the latest agenda. AS EARCH · F Agenda Evening Programs ES MEDRAD Interventional® Long-term Clinical Data of Paccocath® Technology, Preclinical Evidence, and Planned Cotavance® Peripheral Study Designs The Moscone Center, Presentation Theater North, Napa Valley (Located in Hall D) Sponsored by MEDRAD Interventional 8:45 pm - Discussion Panel ARDIO · C V 1:15 pm - Adjourn 8:15 pm - Discussion Panel N 12:55 pm - Discussion with Audience Q&A Panel 8:03 pm - Importance of Baseline Myocardial Viability Jeroen J. Bax O 12:45 pm - Carotid Intervention John R. Laird Jr Agenda 8:00 pm - Introduction and Session Goals Gregg W. Stone - N o v e m b e r 7 - 11 , 2 0 11 12:35 pm - Chronic Total Occlusion Jeffrey W. Moses Gerry Wilkins, MD Dunedin Hospital Dunedin, New Zealand 7:00 pm - Dinner Reception D AT I 12:25 pm - Transcathether Aortic Valve Interventions Roxana Mehran Hyo Soo Kim, MD Seoul National University Hospital Seoul, South Korea Agenda UN 12:15 pm - Managing Complexity for Improved Safety and Outcomes: Practical Methods and Tools for the Operator in Complex Cases Roxana Mehran Sharad Shetty, MD Royal Perty Hospital Perth, Australia O Lunch with be provided for all symposium attendees Satellite Symposia Agenda T r a n s c at h e t e r Cardiovascular Therapeutics Preparing the Interventionalist for the Future: An Interactive Workshop Hilton San Francisco, Grand Ballroom AB Sponsored by Cardiovascular Research Foundation Supported through an educational grant from Medtronic CardioVascular This activity has been approved for AMA PRA Category 1 Credit™ Chairs William A. Gray, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Martin B. Leon, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY www . tctc o n f e r ence . c o m 161 Satellite Symposia ARDIO · C V N UN D AT I O John D. Carroll, MD University of Colorado Denver Aurora, CO O Deepak L. Bhatt, MD, MPH VA Boston Healthcare System and Brigham and Women's Hospital Boston, MA CULAR · R EARCH · F Faculty 8:32 pm - Discussion with Audience Q&A AS ES Horst Sievert, MD, PhD CardioVascular Center Frankfurt, Sankt Katharinen Frankfurt, Germany At the Razor’s Edge: Establishing a New Standard of Care in Acute Myocardial Infarction Hilton San Francisco, Imperial Ballroom/ Franciscan Room Sponsored by Cardiovascular Research Foundation Supported through an educational grant from Multiple Commercial Supporters Michael J. Davidson, MD Brigham and Women's Hospital Boston, MA This activity has been approved for AMA PRA Category 1 Credit™ Saibal Kar, MD Cedars-Sinai Medical Center Los Angeles, CA Christian W. Hamm, MD Kerckhoff Clinic Bad Nauheim, Germany Alan B. Lumsden, MD Methodist DeBakey Heart and Vascular Center Houston, TX Gregg W. Stone, MD NewYork-Presbyterian Hospital/Columbia University Medical Center New York, NY Ganesh Manoharan, MD Royal Victoria Hospital Belfast, United Kingdom Faculty Manish A. Parikh, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Jeffrey J. Popma, MD Beth Israel Deaconess Medical Center Boston, MA Sam Radhakrishnan, MD Schulich Heart Center, Sunnybrook Hospital Toronto, Canada Mathew Williams, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Agenda Chairs C. Michael Gibson, MD Beth Israel Deaconess Medical Center Boston, MA Paul A. Gurbel, MD Sinai Hospital of Baltimore System Baltimore, MD Roxana Mehran, MD Mount Sinai Hospital New York, NY 8:00 pm - Facility and Staffing Considerations Alan B. Lumsden 8:10 pm - Discussion Panel 8:40 pm - Physician Training Requirements for the “Interventional Futurist” William A. Gray 8:50 pm - Discussion Panel 9:20 pm - New Patients for New Interventional Therapies Horst Sievert 8:52 pm - The Evolution of Antiplatelet Therapy During Primary PCI Shamir Mehta 9:04 pm - Discussion with Audience Q&A 9:08 pm - Clopidogrel, Prasugrel and Ticagrelor During Primary PCI: Pharmacokinetic and Pharmacodynamic Differences Paul A. Gurbel 9:20 pm - Discussion with Audience Q&A 9:24 pm - Clopidogrel, Prasugrel and Ticagrelor During Primary PCI: Clinical Outcomes C. Michael Gibson 9:36 pm - Discussion with Audience Q&A 9:40 pm - Discussion with Audience Q&A: Establishing a New Standard of Care in Acute Myocardial Infarction Moderators: Gregg W. Stone Discussants: C. Michael Gibson, Paul A. Gurbel, Roxana Mehran, Shamir Mehta, Harvey D. White 10:00 pm - Adjourn Friday, November 11 Shamir Mehta, MD, MSc Hamilton Health Sciences Hamilton, Canada Breakfast Meetings Harvey D. White, DSc Green Lane Cardiovascular Service, Auckland City Hospital Auckland, New Zealand First-in-Man Chronic Total Occlusion Crossing Using the Directional OCT-Guided Ocelot CTO Catheter The Moscone Center, Room 124 Sponsored by Avinger, Inc. 7:00 pm - Dinner Reception 8:00 pm - Introduction and Session Goals Gregg W. Stone 8:04 pm - The Evolution of Reperfusion Therapies: From Thrombolysis to PCI (and From Slow to Fast)! Harvey D. White 8:16 pm - Discussion with Audience Q&A 8:20 pm - The Evolution of Catheter-Based Therapies in STEMI: From Balloons to Drug-Eluting Stents and Mechanical Approaches to Thrombus Christian W. Hamm 9:30 pm - Discussion Panel 10:00 pm - Adjourn program · 8:48 pm - Discussion with Audience Q&A Agenda 7:00 pm - Dinner Reception 162 8:36 pm - The Evolution of Antithrombin Therapy During Primary PCI Roxana Mehran T r a n s c a t h ete r C a r d i o v a s c u l a r T h e r a pe u tic s Faculty Sean F. Janzer, MD Mainline Health, Bryn Mawr Hospital Bryn Mawr, PA John B. Simpson, MD, PhD CEO, Founder, Avinger Inc Redwood City, CA Christian Vande Velde Garmin Cervelo Pro Cycling Team Lemont, IL Agenda 6:30 am - Breakfast 7:00 am - From the Tour de France to TCT Christian Vande Velde The World’s Premier Interventional Experience TCT2011 7:35 am - First-in-Man Chronic Total Occlusion Crossing Using the Directional OCT-Guided Ocelot CTO Catheter John B. Simpson Moderator: Sean F. Janzer CULAR · R O N EARCH · F UN D AT I O Guidewire Design and Selection: A User’s Guide The Moscone Center, Room 123 Sponsored by Cardiovascular Research Foundation 7:30 am - Hydrophilic and Support Wires Ajay J. Kirtane 7:40 am - CTO Wires: Antegrade and Retrograde Approaches Craig A. Thompson 7:50 am - Discussion and Audience Q&A Panel 8:00 am - Adjourn Management of Complex Patients, Award Winning Case Presentations The Moscone Center, Room 120 Sponsored by Cardiovascular Research Foundation Supported through an educational grant from ABIOMED, Inc. Use of Intraaortic Balloon Counterpulsation in Percutaneous Aortic Valve Procedures and Complex PCI: Selected Cases The Moscone Center, Room 121 Sponsored by Cardiovascular Research Foundation Supported through an educational grant from MAQUET Cardiovascular. Moderators Duane S. Pinto, MD, MPH Beth Israel Deaconess Medical Center Boston, MA Jose M. Wiley, MD Mount Sinai Medical Center New York, NY Scholarship Winners Chairs Gill Buchanan, MD San Raffaele Scientific Institute Milan, Itlay Supported through an educational grant from Abbott Vascular and Medtronic CardioVascular Roxana Mehran, MD Mount Sinai Medical Center New York, NY Vinod Patel, MD Mount Sinai Medical Center New York, NY This activity has been approved for AMA PRA Category 1 Credit™ Theodore L. Schreiber, MD Cardiovascular Consultants Warren, MI Alice Perlowski, MD Evanston Hospital, NorthShore University Health System Chicago, IL Chairs Ajay J. Kirtane, MD, SM NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Martin B. Leon, MD NewYork-Presbyterian Hospital/ Columbia University Medical Center New York, NY Faculty Christopher E. Buller, MD Vancouver General Hospital Vancouver, Canada scholarship winners Gopi Manthripragada, MD UCLA Moorpark, CA Faramarz Tahrani, MD UC Davis Medical Center Sacramento, CA Michael Tempelhof, MD Northwestern University Chicago, IL Agenda 6:30 am - Breakfast Craig A. Thompson, MD, MMSc Yale New Haven Hospital New Haven, CT 7:00 am - Building an Impella Program Confirmed Theodore L. Schreiber Agenda 7:15 am - Impella Assisted High Risk Unprotected LM PCI Faramarz Tahrani 6:30 am - Breakfast 7:00 am - Welcome and Introductions Martin B. Leon 7:05 am - Anatomy and Design of Coronary Guidewires 101: Engineering for the Interventionalist Christopher E. Buller 7:15 am - Applied Use of Coronary Guidewires: Basic Principles Martin B. Leon 7:25 am - Q&A - N o v e m b e r 7 - 11 , 2 0 11 AS ES ARDIO · C V 8:00 am - Adjourn Case Presentations Satellite Symposia 7:20 am - Understanding Biological and Mechanical Markers to Cross CTOs Using Optical Coherence Tomography Sean F. Janzer T r a n s c at h e t e r Cardiovascular Therapeutics Agenda 6:30 am - Breakfast 7:00 am - The Vital Role of IABP in a Rare Case of Left Main Thrombotic Occlusion Following Balloon Aortic Valvuloplasty Gill Buchanan 7:15 am - Q&A 7:20 am - Intraaortic Balloon Pump Counterpulsation for Hemodynamic Collapse During Transcatheter Aortic Valve Implantation Alice Perlowski 7:35 am - Q&A 7:40 am - Complex PCI with IABP Support in a Patient with Hypoplastic Aorta Vinod Patel 7:55 am - Q&A 8:00 am - Adjourn 7:30 am - Impella as a Bridge to the First Successful Utilization of the HeartWare Assist Device for Biventricular Failure in North America Michael Tempelhof 7:40 am - Q&A 7:45 am - A Second Chance Gopi Manthripragada 7:55 am - Q&A 8:00 am - Adjourn www . tctc o n f e r ence . c o m 163 Women’s Heart Health Summit Satellite Symposia In Pursuit of Excellence: Improving Cardiovascular Outcomes in Women In PursuIt of ExcEllEncE: Improving Cardiovascular Outcomes in Women friday, December 9, 2011 11:00 am-2:00 pm The Princeton Club 15 West 43rd Street New York, NY SummIt ChaIr Roxana Mehran, MD KEynotE addrESS Cindy L. Grines, MD Please join us for a special luncheon program featuring prominent experts in research, academia, and health policy as we examine the importance of gender in cardiovascular disease research. The Summit will address the state of heart disease in women: what has been achieved and how can we fill the gaps in the future. For more information or to register, please visit www.pulsegala.org/womensheartsummit 164 program · T r a n s c a t h ete r C a r d i o v a s c u l a r T h e r a pe u tic s The World’s Premier Interventional Experience TCT2011 T r a n s c at h e t e r Cardiovascular Therapeutics A Passion for Innovation Satellite Symposia C A R D I O VA S C U L A R RESEARCH F O U N D AT I O N - N o v e m b e r 7 - 11 , 2 0 11 Pioneering New Therapies for the Treatment of Heart Disease More than 81 million people live with heart disease worldwide. Many of them will benefit from interventional procedures developed or refined by the Cardiovascular Research Foundation (CRF) . . . . WE INVESTIGATE Early Stage Technologies During Preclinical Research WE EVALUATE Promising New Therapies by Designing and Implementing Multiple Phases of Human Clinical Trials WE EDUCATE Medical Professionals and the Public to Enhance Patient Outcomes Visit us at the Partnership Pavilion on the first floor of Moscone North. www . tctc o n f e r ence . c o m 165 493 - 512 4 4 8 4 86 5 4 8 92 7 4 49 91 0 89 697 - 710 Congenital Heart Disease and Acquired Structural Defects 711 - 726 Valvular Heart Disease - Aortic 727 - 794 Valvular Heart Disease - Mitral 795 - 807 431 4 40 6 0 40 5 39 4 8 40 39 3 9 40 400 1 2 40 495 494 CORONARY 39 0 3 39 3 95 4 3 9 6 93 3 39 92 1 39 7 382-389 (8 posters) Unstable Anginaand NSTEMI 354 355 341 346 347 350 342 345 348 349 343 344 353 338 363 356 357 358 385 389 14 15 3 4 4 08 3 382 8 4 6 41 384 388 2 09 41 11 387 383 04 4 41 407-415 (9 posters) Heart Disease in the Elderly 364 365 373 366 367 368 340 351 372 369 362 359 370 360 352 371 361 339 328-381 (54posters) - STEMI Poster 328 337 329 330 32 320 7 32 3225 3261 32 331 336 332 333 30 2981 3027 29 30 296 3 30 3069 3105 30 31 304 1 31 312 9 3183 31 31 3147 3009 29 3087 30 2165 31 3243 32 290-327 (38poster faces) - Left Main and Bifurcation Stenting 226 235 236 245 247 252 246 253 256 257 255 258 254 259 262 263 261 264 260 265 267 268 266 269 1106 1107 2045 20 2012 20 2078 20 186 191 190 193 189 194 188 195 196 187 183 1854 18 176 1827 17 169 164 1685 16 1750 17 1818 17 158 161 1609 15 1632 16 1676 16 1741 17 151 1809 17 1732 17 152 197 206 209 192 153 200 210 211 212 215 154 1989 19 203 2134 21 155 150 - 191 (42posters faces) - Adjunct Pharmacology 156 1197 1198 1199 1200 1201 1202 1203 1204 1205 1206 1207 1208 1209 1210 1211 1212 1213 1214 1215 1216 1217 1218 1219 150 270 271 272 1220 270-280(11 poster faces) Chronic Total Occlusion 277 276 280 273 279 274 278 275 334 335 290 282 281 288 287 286 285 225 227 234 237 244 248 251 281-289 poster faces) - In-stent Restenosis and Drug-eluting Balloons 224 228 233 238 243 230 231 240 241 le, rbab 229 232 239 242 249 250 abso udies - Bio tent St ces) S er fa e Metal r post (78 and Ba , -269 192 Eluting gDru 223 222 221 220 284 283 289 291 292 293 294 295 379 380 381 376 377 378 374 375 416-425(10 poster faces) Heart Disease in Women 416 417 418 425 421 422 420 423 419 424 434 433 432 436 435 428 429 430 426 427 426 - 437 (11 posters) - Heart Disease in Diabetics 496 493 48 84 Structural 8 44 44 7 45 9 44 0 44 1 45 4 44 6 44 5 11 2 03 4 0 1 0 5 5 505 2 5 5 497 51 50 9 1 06 98 50 08 50 00 75 94 5 5 50 49 493 - 512 (20 posters) - Contrast Nephropathy and Chronic Kidney Disease 621 - 696 Physiologic Lesion Assessment 1133 1132 Endovascular CHALLENGING CASES 602 - 620 Intravascular Imaging: IVUS, OCT, Spectroscopy, and Other 1131 1130 468 - 492 Contrast Nephropathy and Chronic Kidney Disease OTHER Coronary Angiography and CTA 1129 1128 554 - 601 1127 1126 437 - 467 Cardiogenic Shock, Heart Failure, and Hemodynamic Support 0 4 4 44 9 4 1 4 43 2 43 3 44 43 8 7 Imaging 1125 1124 543 - 553 Peripheral Vascular Intervention (non carotid, non neurovascular) 1123 1122 513 - 542 Carotid and Neurovascular Intervention 1121 Vascular Access and Closure CHALLENGING Basic Science, Animal Models and Preclinical Studies 390 - 406 (17 posters) PCI Outcomes 426 - 436 1102 1103 416 - 425 Heart Disease in Diabetics 1104 1105 407 - 415 Heart Disease in Women 1108 1109 390 - 406 Heart Disease in the Elderly 1110 1111 382 - 389 PCI Outcomes 1112 1113 328 - 381 Unstable Angina and NSTEMI t Failure, 290 - 327 STEMI Posters 1114 1115 281 - 289 Left Main and Bifurcation Stenting 1116 1117 270 - 280 In-stent Restenosis and Drug-Eluting Balloons cience, Animal Models and Preclinical Studies 192 - 269 Chronic Total Occlusion 1118 1119 150 - 191 Bioabsorbable, Drug-Eluting, and Bare Metal Stent Studies 1120 Adjunct Pharmacology 40 7 # A b s t r a ct s C atag o r i e s # Abstracts 150 - 191 192 - 269 270 - 280 281 - 289 290 - 327 328 - 381 382 - 389 390 - 406 407 - 415 416 - 425 426 - 436 437 - 467 468 - 492 493 - 512 513 - 542 543 - 553 554 - 601 219 218 217 216 157 T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s program · 166 602 - 620 621 - 696 697 - 710 711 - 726 727 - 794 795 - 807 Poster abstract Map Coronary Other 1101 1150 1151 4 46 46 3 46 5 46 6 46 7 46 0 46 2 46 1 CHALLENGING CASES 4 46 47 70 9 4 86 1 4 47 47 85 24 4 73 3 53 1164 39 85 53 T r a n s c at h e t e r Cardiovascular Therapeutics TCT2011 778 779 777 760 761 762 758 759 734 745 744 741 743 742 728 729 730 731 795 - 807 (13 posters) - Valvular Heart Disease - Mitral 780 781 782 776 763 764 765 802 801 783 784 785 727 - 794 (68 posters) - Valvular Heart Disease - Aortic 766 757 733 732 767 748 746 747 756 749 750 751 797 796 798 795 807 786 787 788 775 768 769 770 803 800 804 799 805 806 789 790 791 691 690 686 679 687 678 688 677 STRUCTURAL 657 658 656 659 647 644 663 662 674 675 673 676 664 661 653 654 652 655 651 648 IMAGING 660 643 570 569 573 568 571 572 577 564 574 567 575 566 576 565 563 581 559 578 562 579 561 580 560 582 558 583 557 584 556 554 585 555 ENDOVASCULAR 1196 1194 1195 1192 1193 1190 1191 1188 1189 1186 1187 1184 1185 1182 1183 1180 1181 1178 1179 1176 1177 1174 1175 1172 1173 1170 1171 1178 1169 1166 1167 1165 735 740 792 774 771 755 752 727 793 772 753 739 738 794 773 754 736 737 704 - 719 (16 posters) - Congenital Heart Disease & Aquired Structural Defects 720 721 722 723 724 725 726 711 718 717 716 715 714 713 712 719 692 685 680 646 645 637 638 636 639 627 624 553 549 546 550 545 551 544 552 543 641 642 640 623 622 621 650 649 670 671 669 672 668 665 667 666 710 709 708 707 706 705 704 697 698 699 700 701 702 703 697- 710 (14 posters) - Physiology Lesion assessment 693 684 681 689 694 683 682 633 634 632 635 631 628 626 625 610 611 612 609 616 613 630 629 606 607 605 608 620 617 615 614 695 696 604 619 618 589 598 588 599 587 600 548 547 590 597 602- 620 (19 posters) Coronary Angiography and CTA 595 594 603 602 5 52 5 52 52 27 8 5 51 19 0 5 2 13 6 8 1 5 5 52 51 52 22 51 14 55 75 3 5 24 16 Vascular Access and Closure 513 - 542 (30 posters) 5 5 42 3 7 5 54 41 0 1162 1163 5 52 53 30 9 5 36 1 5 53 35 4 2 1160 1161 53 586 601 Peripheral Vascular Intervention (non coraotid, non neurovascular 554 - 601 (48 posters) 1154 1155 4 47 47 78 7 4 84 9 4 48 48 83 04 2 81 8 1144 1143 1142 1141 1140 1139 1138 1137 1136 1148 1149 6 45 45 5 45 7 45 8 45 9 45 2 45 4 45 3 621 - 696 (76 posters) - Intravascular Imaging: IVUS, OCT, Spectroscopy, and Other 593 596 592 591 543-553 (11 posters) - Carotid and Neurovascular Intervention 1156 1157 R 1145 1135 1134 1146 1147 G CASES 1158 1159 46 The World’s Premier Interventional Experience 1152 1153 167 www . t c t c o n f e r e n c e . c o m 437 - 467 (31 posters) - Basic 468- 492(25 posters) - Cardiogenic Shock, Hea and Hemodynamic Support Moscone Center Map 168 program · T r a n s c at h e t e r C a r d i o va s c u l a r T h e r a p e u t i c s The World’s Premier Interventional Experience TCT2011 TCT Advisory Faculty Lounge Presentation theater North - Sonoma Valley Endovascular/ Structural Theater T r a n s c at h e t e r Cardiovascular Therapeutics Right Theater: International Society Case Theater Presentation Theater North: Sonoma Valley Cath Lab of the Future computer computer PW PW PW computer PW Presentation theater North - Napa Valley PW Partnership Pavilion computer Hands on Heart Presentation Theater North: Napa Valley Left Theater: Challenging Case Theater Physcian Attendee Lounge Coronary Theater www . t c t c o n f e r e n c e . c o m 169 Visit the ACC booth, located in the North Hall Concourse, Lower Level in the CRF Partner Pavilion, to learn more about the ACC’s Interventional Cardiology offerings including: • Membership in the ACC and the Interventional Scientific Section • ACC.12 and the ACC-i2 with TCT Interventional Learning Pathway • Journal of the American College of Cardiology (JACC ) and JACC: Interventions • ACC’s Interventional Clinical Collection in collaboration with TCTMD on CardioSource.org Plus, stop by the booth in order for your chance to win free registration and housing to ACC.12, where you’ll experience the ACC’s passion for science, education and networking! Don’t miss Hot Topics in Clinical Cardiology: ACC.11 Highlights for the Interventional, Invasive and General Cardiologist on Nov. 8 from 1:00 – 6:00 p.m. in room 132. ©2011 American College of Cardiology X11109 Launching January 2012 THE POWER OF COLLABORATION Take a sneak peek PILOT ISSUE AT: Booth 2334 in association with 11-1624 Ultra-modern ISO 13485 & cGMP Qualified Manufacturing facility. Over 10,000Sq Ft of Class 10,000Sq Ft clean rooms; with all key process conducted under Class 100 LAF. EtO Sterilization & all microbial QA Tests conducted in-house. Tip to Hub manufacturing of Stent systems and PTCA balloons is done in-house. Meril Life Sciences Pvt. Ltd., Muktanand Marg, Chala, Vapi 396 191. Gujarat. India. T + 91 260 3052 100 F + 91 260 3052 125 E [email protected] W www.merillife.com A9114-9161-A1-4A00 © 2011 Siemens Medical Solutions USA, Inc. Visit us at TCT, Booth 916 Are you ready for the long run? The road to Sustainable Cardiovascular Care is here. www.usa.siemens.com/cardiovascular The dynamics of our healthcare system may be changing but the need for high-quality care for every individual patient remains the same. You need to be able to provide the best possible care for an increasing number of patients—efficiently—not just today but for years to come. technology, and support to enable sounder decisions, safer procedures, stronger operations, and smarter investments. Helping you deliver quality outcomes affordably, again and again. That’s Sustainable Cardiovascular Care. Through its longstanding commitment to innovation and technological integration, Siemens Healthcare is helping cardiovascular care move forward. Providing the systems, Answers for life. The XIENCE® V and XIENCE nano™ Everolimus Eluting Coronary Stent on the MULTI-LINK VISION® or MULTI-LINK MINI VISION® Delivery System INDICATIONS The XIENCE V Everolimus Eluting Coronary Stent System (XIENCE V stent) is indicated for improving coronary luminal diameter in patients with symptomatic heart disease due to de novo native coronary artery lesions (length ≤ 28 mm) with reference vessel diameters of 2.25 mm to 4.25 mm. CONTRAINDICATIONS The XIENCE V stent is contraindicated for use in patients: • Whocannotreceiveantiplateletand/oranticoagulant therapy • Withlesionsthatpreventcompleteangioplasty balloon inflation or proper placement of the stent or stent delivery system • Withhypersensitivityorcontraindicationto everolimus or structurally-related compounds, cobalt, chromium, nickel, tungsten, acrylicpolymers or fluoropolymers. WARNINGS • Ensurethattheinnerpackagesterilebarrierhas not been opened or damaged prior to use. • Judiciouspatientselectionisnecessary because device use has been associated with stent thrombosis, vascular complications, and/ or bleeding events. • Thisproductshouldnotbeusedinpatients who are not likely to comply with the recommended antiplatelet therapy. PRECAUTIONS • Stentimplantationshouldonlybeperformed by physicians who have received appropriate training. • Stentplacementshouldbeperformedat hospitals where emergency coronary artery bypass graft surgery is accessible. • Subsequentrestenosismayrequirerepeat dilatation of the arterial segment containing the stent. Long-term outcomes following repeat dilatation of the stent are presently unknown. • Risksandbenefitsshouldbeconsideredin patients with severe contrast agent allergies. • Careshouldbetakentocontroltheguiding catheter tip during stent delivery, deployment and balloon withdrawal. Use fluoroscopy to avoid arterial damage. • Stentthrombosisisalow-frequencyevent thatisfrequentlyassociatedwithmyocardial infarction (MI) or death. • WhenDESareusedoutsidethespecified Indications for Use, patient outcomes may differ from the results observed in the XIENCE V SPIRIT family of trials. • ComparedtousewithinthespecifiedIndications forUse,theuseofDESinpatientsandlesions outside of the labeled indications may have an increased risk of adverse events, including stent thrombosis, stent embolization, MI or death. • Orallyadministeredeverolimuscombinedwith cyclosporine is associated with increased serum cholesterol and triglycerides levels. • Apatient’sexposuretodrugandpolymeris proportional to the number of and total length of implanted stents. See Instructions for Use for current data on multiple stent implantation. • SafetyandeffectivenessoftheXIENCEV stent have not been established for subject populations with the following clinical settings: • Patientswithpriortargetlesionorin-stent restenosis related brachytherapy, patients in whom mechanical atherectomy devices or laser angioplasty devices are used simultaneously, women who are pregnant or lactating, men intending to father children, pediatric patients, unresolved vessel thrombus at the lesion site, coronary artery reference vessel diameters < 2.25 mm or > 4.25 mm or lesion length > 28 mm, lesions located in saphenous vein grafts, unprotected left main coronary artery, ostial lesions, chronic total occlusions, lesions located at a bifurcation or previously stented lesions, diffuse disease orpoorflow(TIMI<1)distaltotheidentified lesions,excessivetortuosityproximaltoor within the lesion, recent acute myocardial infarction (AMI) or evidence of thrombus in target vessel, moderate or severe lesion calcification,multivesseldiseaseandin-stent restenosis. • Everolimushasbeenshowntoreducethe clearance of some prescription medications when it was administered orally along with cyclosporine (CsA). Formal drug interaction studies have not been performed with the XIENCE V stent because of limited systemic exposuretoeverolimuselutedfromXIENCEV. • Everolimusisanimmunosuppressiveagent. Consideration should be given to patients taking other immunosuppressive agents or who are at risk for immune suppression. • Oraleverolimususeinrenaltransplantpatients and in patients treated for advanced renal cell carcinoma was associated with increased serum cholesterol and triglycerides that in somecasesrequiredtreatment. • Non-clinicaltestinghasdemonstratedthatthe XIENCE V stent, in single and in overlapped configurationsupto68mminlength,isMR Conditional. It can be scanned safely under the conditions in the Instructions for Use. • TheXIENCEVstentshouldbehandled, placed, implanted and removed according to the Instructions for Use. POTENTIAL ADVERSE EVENTS Adverse events (in alphabetical order) which may be associated with coronary stent use in native coronary arteries include but are not limited to: • Abruptclosure,Accesssitepain,hematoma, or hemorrhage, Acute myocardial infarction, Allergic reaction or hypersensitivity to contrast agent or cobalt, chromium, nickel, tungsten, acrylic and fluoropolymers; and drug reactions to antiplatelet drugs or contrast agent, Aneurysm, Arterial perforation and injury to the coronary artery, Arterial rupture, XIENCEV,XIENCEnano,MULTI-LINKVISIONandMULTI-LINKMINIVISION are trademarks of the Abbott Group of Companies. ©2011 Abbott. All rights reserved. AP2935460-US Rev. A 09/11 Arteriovenousfistula,Arrhythmias,atrialand ventricular, Bleeding complications, which mayrequiretransfusion,Cardiactamponade, Coronary artery spasm, Coronary or stent embolism, Coronary or stent thrombosis, Death,Dissectionofthecoronaryartery,Distal emboli (air, tissue or thrombotic), Emergent or non-emergent coronary artery bypass graft surgery, Fever, Hypotension and/or hypertension, Infection and pain at insertion site, Injury to the coronary artery, Ischemia (myocardial), Myocardial infarction (MI), Nausea and vomiting, Palpitations, Peripheral ischemia (due to vascular injury), Pseudoaneurysm, Renal Failure, Restenosis of the stented segment of the artery, Shock/pulmonary edema, Stroke/ cerebrovascular accident (CVA), Total occlusion of coronary artery, Unstable or stable angina pectoris, Vascular complications including at theentrysitewhichmayrequirevesselrepair, Vessel dissection. Adverse events associated with daily oral administration of everolimus to organ transplant patients include but are not limited to: • Abdominalpain(includingupperabdominal pain);Anemia;Angioedema;Anorexia; Asthenia;Constipation;Cough;Delayed woundhealing/fluidaccumulation;Diarrhea; Dyslipidemia(includinghyperlipidemiaand hypercholesterolemia);Dyspnea;Dysgeusia; Dyspepsia;Dysuria;Dryskin;Edema (peripheral);Epistaxis;Fatigue;Headache; Hematuria; Hyperglycemia (may include new onset of diabetes); Hyperlipidemia; Hyperkalemia; Hypertension; Hypokalemia; Hypomagnesemia; Hypophosphatemia; Increased serum creatinine; Infections and serious infections: bacterial, viral, fungal, and protozoal infections (may include herpes virus infection, polyoma virus infection which may be associated with BK virus associated nephropathy, and/or other opportunistic infections); Insomnia; Interaction with strong inhibitors and inducers of CY3PA4; Leukopenia; Lymphoma and other malignancies (including skin cancer); Male infertility (azospermia and/or oligospermia); Mucosal inflammation (including oral ulceration and oral mucositis); Nausea; Neutropenia; Non-infectious pneumonitis; Pain:extremity,incisionsiteandprocedural, andback;Proteinuria;Pruritus;Pyrexia;Rash; Stomatitis; Thrombocytopenia; Thrombotic microangiopathy (TMA)/Thrombotic thrombocytopenic purpura (TTP)/Hemolytic uremic syndrome (HUS); Tremor; Urinary tract infection; Upper respiratory tract infection; Vomiting. • Livevaccinesshouldbeavoidedandclose contact with those that have had live vaccines should be avoided. Fetal harm can occur when administered to a pregnant woman. There may be other potential adverse events that are unforeseen at this time. Prior to use, please reference the Instructions for Use at www.AbbottVascular.com/ifu for more information on indications, contraindications, warnings, precautions and adverse events. Advance your vascular procedures. We believe there are no limits to what you can do—whether you’re treating aortic disease, preventing pulmonary embolism or fighting PAD. That’s why we offer more than just proven vascular products. With Cook Medical, you can: EMBOLIC THERAPIES ENDOVASCULAR AORTIC REPAIR LEAD MANAGEMENT • Expand your interventional skill set. • Partner with a leader in physician-driven innovation. Cook Medical—Working with you to improve patient outcomes. LEG THERAPIES PULMONARY EMBOLISM PREVENTION RENAL THERAPIES STRUCTURAL HEART ACCESS Download the CRF Meetings App for iPhone and iPad to get mobile access to TCT 2011. © COOK 2011 • Rely on our experienced team of specialists. PI-BADV-TCTP-EN-201109 • Share best practices with physicians worldwide. Everolimus Eluting Coronary Stent System Because I put safety first I use XIENCE. Chosen with conviction Contact your Abbott Vascular sales representative for more information. Indications: The XIENCE V® Everolimus Eluting Coronary Stent System (XIENCE V® stent) is indicated for improving coronary luminal diameter in patients with symptomatic heart disease due to de novo native coronary artery lesions (length ≤ 28 mm) with reference vessel diameters of 2.25 mm to 4.25 mm. For Important Safety Information, see page 176. Source: SPIRIT III 2-year and SPIRIT II 2-year stent thrombosis rates from XIENCE V® IFU. For more information, visit our website at www.AbbottVascular.com ©2011 Abbott. All rights reserved. AP2935460-US Rev. A 09/11 TCT 2011 Visit us at booth 1017