Publication - American Heart Association
Transcription
Publication - American Heart Association
EXPECT REGISTER BY OCT. 7 TO SAVE! THINGS SCIENTIFIC SESSIONS PREVIEW BIG REASONS TO ATTEND BIG SCIENCE AND CLINICAL CONTENT BIG SPEAKERS BIG TECHNOLOGY BIG LEARNING BIG FUN IN ORLANDO AMERICAN HEART ASSOCIATION SCIENTIFIC SESSIONS 2015 WELCOME DEAR COLLEAGUES, It is our pleasure to invite you to attend Scientific Sessions 2015 in Orlando. The American Heart Association’s annual meeting offers a unique opportunity to gather and network with colleagues from around the world in an educational and professional environment. This event features five days of the best in science and cardiovascular clinical practice covering all aspects of basic, clinical, population and translational content. The scope and quality of the scientific exchange make Scientific Sessions the premier cardiovascular research and instructional meeting in the world. Exciting changes have been made to Scientific Sessions’ structure, and new topics have been added to increase the educational offerings available to attendees. Educational sessions this year are organized in 30 areas of interest (tracks) structured to help you find your community within the event. New areas of interest introduced for Sessions 2015 include Workplace Health, Health Tech, Frontiers in Science and Clinical Trialists. Also new this year are the Simulation Zone, featuring hands-on activities at the 3D Body Interact and Mechanical Circulatory Support Simulation, and the Genomics Boot Camp, offering non-scientists and practitioners the The Orange County Convention Center, in Orlando, Florida, will host Scientific Sessions 2015. opportunity to learn about genomics through case-based, active-learning activities. We will continue with the very well-received Case Theaters: Learning at the Movies, which offer 45-minute live presentations of recorded cases, accompanied by panel discussion. Other highlights include an increased number of joint sessions with professional societies from around the world, additional MOC sessions, Professor Rounds of posters, a poster reception highlighting some of the best basic science research, as well as many more. Scientific Sessions continues to evolve and improve with the input from our attendees making an already great meeting even more spectacular. We thank you for your input in the past, and we hope you have the opportunity to experience the enhancements to our meeting. Most importantly, we hope the meeting addresses the greater mission of the American Heart Association, to reduce the burden of cardiovascular disease. Sincerely yours, Frank Sellke, MD, FAHA Chair, Committee on Scientific Sessions Programming Eric Peterson, MD, MPH, FAHA Vice Chair, Committee on Scientific Sessions Programming scientificsessions.org | American Heart Association Scientific Sessions 2015 Preview 1 AMERICAN HEART ASSOCIATION SCIENTIFIC SESSIONS 2015 INSIDE THE BIG Bigger and better: Scientific Sessions 2015 highlights Big reasons you can’t miss Scientific Sessions 2015 Scientific Sessions Week at-a-glance BIG 1 6 8 12 TECHNOLOGY Scientific Sessions 2015 exhibitors Cardiovascular Expert Theaters BIG LEARNING BIG FUN IN ORLANDO Unofficial Satellite Events SCIENCE AND CLINICAL CONTENT Late-Breaking Clinical Trials Clinical Science Special Reports Scientific programming Narrow your focus: 30 areas of interest/tracks CME/CE information BIG BIG REASONS TO ATTEND Welcome from chair and vice chair of the Committee on Scientific Sessions Programming 14 20 21 21 SPEAKERS Scientific Sessions 2015 faculty 22 Welcome to Orlando Orlando attractions BIG 30 32 34 36 36 PLANS Do-now checklist 40 American Heart Association National Center 7272 Greenville Ave. Dallas, TX 75231 214-373-6300 800-242-2453 my.americanheart.org Registration Convention Data Services 508-743-8517 800-748-3583 [email protected] Housing Travel Planners 212-532-1660 877-468-3548 [email protected] Facility Orange County Convention Center 9400 Universal Blvd. Orlando, FL 32819 occc.net For advertising information, visit: [email protected] For additional information regarding Scientific Sessions 2015, please visit scientificsessions.org. The official American Heart Association Conference Preview is published by AHA as an exclusive service to Scientific Sessions 2015 attendees. While every effort is made to ensure accuracy, AHA makes no warranties, expressed or implied, related to the information. Information contained herein is subject to change without notice. No part of this publication may be reproduced, stored or transmitted without written permission from AHA. © 2015 American Heart Association. All rights reserved. 2 American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org Add Corlanor ® to maximally tolerated doses of beta-blockers and help give appropriate patients with stable, symptomatic chronic heart failure... MORE HOME. LESS HOSPITAL. Learn how you can DO MORE with Corlanor® to reduce the risk of hospitalization for worsening heart failure 1 CorlanorHCP.com Indication Corlanor® (ivabradine) is indicated to reduce the risk of hospitalization for worsening heart failure in patients with stable, symptomatic chronic heart failure with left ventricular ejection fraction ≤ 35%, who are in sinus rhythm with resting heart rate ≥ 70 beats per minute and either are on maximally tolerated doses of beta-blockers or have a contraindication to beta-blocker use. Important Safety Information Contraindications: Corlanor® is contraindicated in patients with acute decompensated heart failure, blood pressure < 90/50 mmHg, sick sinus syndrome, sinoatrial block, 3rd degree atrioventricular block (unless a functioning demand pacemaker is present), a resting heart rate < 60 bpm prior to treatment, severe hepatic impairment, pacemaker dependence (heart rate maintained exclusively by the pacemaker), and concomitant use of strong cytochrome P450 3A4 (CYP3A4) inhibitors. Fetal Toxicity: Corlanor® may cause fetal toxicity when administered to a pregnant woman based on embryo-fetal toxicity and cardiac teratogenic effects observed in animal studies. Advise females to use effective contraception when taking Corlanor®. Atrial Fibrillation: Corlanor® increases the risk of atrial fibrillation. The rate of atrial fibrillation in patients treated with Corlanor® compared to placebo was 5% vs. 3.9% per patient-year, respectively. Regularly monitor cardiac rhythm. Discontinue Corlanor® if atrial fibrillation develops. © 2015 Amgen Inc. All rights reserved. Not for reproduction. USA-998-108642 Bradycardia and Conduction Disturbances: Bradycardia, sinus arrest and heart block have occurred with Corlanor®. The rate of bradycardia in patients treated with Corlanor® compared to placebo was 6% (2.7% symptomatic; 3.4% asymptomatic) vs. 1.3% per patient-year, respectively. Risk factors for bradycardia include sinus node dysfunction, conduction defects, ventricular dyssynchrony, and use of other negative chronotropes. Concurrent use of verapamil or diltiazem also increases Corlanor® exposure, contributes to heart rate lowering, and should be avoided. Avoid use of Corlanor® in patients with 2nd degree atrioventricular block unless a functioning demand pacemaker is present. Adverse Reactions: The most common adverse reactions reported at least 1% more frequently with Corlanor® than placebo and that occurred in more than 1% of patients treated with Corlanor® were bradycardia (10% vs. 2.2%), hypertension or increased blood pressure (8.9% vs. 7.8%), atrial fibrillation (8.3% vs. 6.6%), and luminous phenomena (phosphenes) or visual brightness (2.8% vs. 0.5%). Please see Brief Summary of full Prescribing Information on adjacent page. Reference: 1. Corlanor® (ivabradine) Prescribing Information, Amgen. Corlanor® (ivabradine) BRIEF SUMMARY OF PRESCRIBING INFORMATION Please see package insert for full Prescribing Information 1. INDICATIONS AND USAGE Corlanor is indicated to reduce the risk of hospitalization for worsening heart failure in patients with stable, symptomatic chronic heart failure with left ventricular ejection fraction ≤ 35%, who are in sinus rhythm with resting heart rate ≥ 70 beats per minute and either are on maximally tolerated doses of beta-blockers or have a contraindication to beta-blocker use. 4. CONTRAINDICATIONS Corlanor is contraindicated in patients with: • Acute decompensated heart failure • Blood pressure less than 90/50 mmHg • Sick sinus syndrome, sinoatrial block, or 3rd degree AV block, unless a functioning demand pacemaker is present • Resting heart rate less than 60 bpm prior to treatment [see Warnings and Precautions (5.3)] • Severe hepatic impairment [see Use in Specific Populations (8.6)] • Pacemaker dependence (heart rate maintained exclusively by the pacemaker) [see Drug Interactions (7.3)] • Concomitant use of strong cytochrome P450 3A4 (CYP3A4) inhibitors [see Drug Interactions (7.1)] 5. WARNINGS AND PRECAUTIONS 5.1 Fetal Toxicity Corlanor may cause fetal toxicity when administered to a pregnant woman based on findings in animal studies. Embryo-fetal toxicity and cardiac teratogenic effects were observed in fetuses of pregnant rats treated during organogenesis at exposures 1 to 3 times the human exposures (AUC0-24hr) at the maximum recommended human dose (MRHD) [see Use in Specific Populations (8.1)]. Advise females to use effective contraception when taking Corlanor [see Use in Specific Populations (8.3)]. 5.2 Atrial Fibrillation Corlanor increases the risk of atrial fibrillation. In SHIFT, the rate of atrial fibrillation was 5.0% per patient-year in patients treated with Corlanor and 3.9% per patient-year in patients treated with placebo [see Clinical Studies (14)]. Regularly monitor cardiac rhythm. Discontinue Corlanor if atrial fibrillation develops. 5.3 Bradycardia and Conduction Disturbances Bradycardia, sinus arrest, and heart block have occurred with Corlanor. The rate of bradycardia was 6.0% per patientyear in patients treated with Corlanor (2.7% symptomatic; 3.4% asymptomatic) and 1.3% per patient-year in patients treated with placebo. Risk factors for bradycardia include sinus node dysfunction, conduction defects (e.g., 1st or 2nd degree atrioventricular block, bundle branch block), ventricular dyssynchrony, and use of other negative chronotropes (e.g., digoxin, diltiazem, verapamil, amiodarone). Concurrent use of verapamil or diltiazem will increase Corlanor exposure, may themselves contribute to heart rate lowering, and should be avoided [see Clinical Pharmacology (12.3)]. Avoid use of Corlanor in patients with 2nd degree atrioventricular block, unless a functioning demand pacemaker is present [see Contraindications (4) and Dosage and Administration (2)]. 6. ADVERSE REACTIONS Clinically significant adverse reactions that appear in other sections of the labeling include: • Fetal Toxicity [see Warnings and Precautions (5.1)] • Atrial Fibrillation [see Warnings and Precautions (5.2)] • Bradycardia and Conduction Disturbances [see Warnings and Precautions (5.3)] 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. In the Systolic Heart failure treatment with the If inhibitor ivabradine Trial (SHIFT), safety was evaluated in 3260 patients treated with Corlanor and 3278 patients given placebo. The median duration of Corlanor exposure was 21.5 months. The most common adverse drug reactions in the SHIFT trial are shown in Table 2 [see also Warnings and Precautions (5.2), (5.3)]. Table 2. Adverse Drug Reactions with Rates ≥ 1.0% Higher on Ivabradine than Placebo occurring in > 1% on ivabradine in SHIFT Ivabradine N=3260 Placebo N=3278 Bradycardia 10% 2.2% Hypertension, blood pressure increased 8.9% 7.8% Atrial fibrillation 8.3% 6.6% Phosphenes, visual brightness 2.8% 0.5% Luminous Phenomena (Phosphenes) Phosphenes are phenomena described as a transiently enhanced brightness in a limited area of the visual field, halos, image decomposition (stroboscopic or kaleidoscopic effects), colored bright lights, or multiple images (retinal persistency). Phosphenes are usually triggered by sudden variations in light intensity. Corlanor can cause phosphenes, thought to be mediated through Corlanor’s effects on retinal photoreceptors [see Clinical Pharmacology (12.1)]. Onset is generally within the first 2 months of treatment, after which they may occur repeatedly. Phosphenes were generally reported to be of mild to moderate intensity and led to treatment discontinuation in < 1% of patients; most resolved during or after treatment. 6.2 Postmarketing Experience Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency reliably or establish a causal relationship to drug exposure. The following adverse reactions have been identified during post-approval use of Corlanor: syncope, hypotension, angioedema, erythema, rash, pruritus, urticaria, vertigo, diplopia, and visual impairment. 7. DRUG INTERACTIONS 7.1 Cytochrome P450-Based Interactions Corlanor is primarily metabolized by CYP3A4. Concomitant use of CYP3A4 inhibitors increases ivabradine plasma concentrations, and use of CYP3A4 inducers decreases them. Increased plasma concentrations may exacerbate bradycardia and conduction disturbances. The concomitant use of strong CYP3A4 inhibitors is contraindicated [see Contraindications (4) and Clinical Pharmacology (12.3)]. Examples of strong CYP3A4 inhibitors include azole antifungals (e.g., itraconazole), macrolide antibiotics (e.g., clarithromycin, telithromycin), HIV protease inhibitors (e.g., nelfinavir), and nefazodone. Avoid concomitant use of moderate CYP3A4 inhibitors when using Corlanor. Examples of moderate CYP3A4 inhibitors include diltiazem, verapamil, and grapefruit juice [see Warnings and Precautions (5.3) and Clinical Pharmacology (12.3)]. Avoid concomitant use of CYP3A4 inducers when using Corlanor. Examples of CYP3A4 inducers include St. John’s wort, rifampicin, barbiturates, and phenytoin [see Clinical Pharmacology (12.3)]. 7.2 Negative Chronotropes Most patients receiving Corlanor will also be treated with a betablocker. The risk of bradycardia increases with concomitant administration of drugs that slow heart rate (e.g., digoxin, amiodarone, beta-blockers). Monitor heart rate in patients taking Corlanor with other negative chronotropes. 7.3 Pacemakers Corlanor dosing is based on heart rate reduction, targeting a heart rate of 50 to 60 beats per minute [see Dosage and Administration (2)]. Patients with demand pacemakers set to a rate ≥ 60 beats per minute cannot achieve a target heart rate < 60 beats per minute, and these patients were excluded from clinical trials [see Clinical Studies (14)]. The use of Corlanor is not recommended in patients with demand pacemakers set to rates ≥ 60 beats per minute. 8. USE IN SPECIFIC POPULATIONS 8.1 Pregnancy Risk Summary Based on findings in animals, Corlanor may cause fetal harm when administered to a pregnant woman. There are no adequate and well-controlled studies of Corlanor in pregnant women to inform any drug-associated risks. In animal reproduction studies, oral administration of ivabradine to pregnant rats during organogenesis at a dosage providing 1 to 3 times the human exposure (AUC0-24hr) at the MRHD resulted in embryo-fetal toxicity and teratogenicity manifested as abnormal shape of the heart, interventricular septal defect, and complex anomalies of primary arteries. Increased postnatal mortality was associated with these teratogenic effects in rats. In pregnant rabbits, increased post-implantation loss was noted at an exposure (AUC0-24hr) 5 times the human exposure at the MRHD. Lower doses were not tested in rabbits. The background risk of major birth defects for the indicated population is unknown. The estimated background risk of major birth defects in the U.S. general population is 2 to 4%, however, and the estimated risk of miscarriage is 15 to 20% in clinically recognized pregnancies. Advise a pregnant woman of the potential risk to the fetus. Clinical Considerations Disease-associated maternal and/or embryo/fetal risk Stroke volume and heart rate increase during pregnancy, increasing cardiac output, especially during the first trimester. Pregnant patients with left ventricular ejection fraction less than 35% on maximally tolerated doses of beta-blockers may be particularly heart-rate dependent for augmenting cardiac output. Therefore, pregnant patients who are started on Corlanor, especially during the first trimester, should be followed closely for destabilization of their congestive heart failure that could result from heart rate slowing. Monitor pregnant women with chronic heart failure in 3rd trimester of pregnancy for preterm birth. Data Animal Data In pregnant rats, oral administration of ivabradine during the period of organogenesis (gestation day 6-15) at doses of 2.3, 4.6, 9.3, or 19 mg/kg/day resulted in fetal toxicity and teratogenic effects. Increased intrauterine and post-natal mortality and cardiac malformations were observed at doses ≥ 2.3 mg/kg/day (equivalent to the human exposure at the MRHD based on AUC0-24hr). Teratogenic effects including interventricular septal defect and complex anomalies of major arteries were observed at doses ≥ 4.6 mg/kg/day (approximately 3 times the human exposure at the MRHD based on AUC0-24hr). In pregnant rabbits, oral administration of ivabradine during the period of organogenesis (gestation day 6-18) at doses of 7, 14, or 28 mg/kg/day resulted in fetal toxicity and teratogenicity. Treatment with all doses ≥ 7 mg/kg/day (equivalent to the human exposure at the MRHD based on AUC0-24hr) caused an increase in post-implantation loss. At the high dose of 28 mg/kg/ day (approximately 15 times the human exposure at the MRHD based on AUC0-24hr), reduced fetal and placental weights were observed, and evidence of teratogenicity (ectrodactylia observed in 2 of 148 fetuses from 2 of 18 litters) was demonstrated. In the pre- and postnatal study, pregnant rats received oral administration of ivabradine at doses of 2.5, 7, or 20 mg/kg/day from gestation day 6 to lactation day 20. Increased postnatal mortality associated with cardiac teratogenic findings was observed in the F1 pups delivered by dams treated at the high dose (approximately 15 times the human exposure at the MRHD based on AUC0-24hr). 8.2 Lactation Risk Summary There is no information regarding the presence of ivabradine in human milk, the effects of ivabradine on the breastfed infant, or the effects of the drug on milk production. Animal studies have shown, however, that ivabradine is present in rat milk [see Data]. Because of the potential risk to breastfed infants from exposure to Corlanor, breastfeeding is not recommended. Data Lactating rats received daily oral doses of [14C]-ivabradine (7 mg/kg) on post-parturition days 10 to 14; milk and maternal plasma were collected at 0.5 and 2.5 hours post-dose on day 14. The ratios of total radioactivity associated with [14C]ivabradine or its metabolites in milk vs. plasma were 1.5 and 1.8, respectively, indicating that ivabradine is transferred to milk after oral administration. 8.3 Females and Males of Reproductive Potential Contraception Females Corlanor may cause fetal harm, based on animal data. Advise females of reproductive potential to use effective contraception during Corlanor treatment [see Use in Specific Populations (8.1)]. 8.4 Pediatric Use Safety and effectiveness in pediatric patients have not been established. 8.5 Geriatric Use No pharmacokinetic differences have been observed in elderly (≥ 65 years) or very elderly (≥ 75 years) patients compared to the overall population. However, Corlanor has only been studied in a limited number of patients ≥ 75 years of age. 8.6 Hepatic Impairment No dose adjustment is required in patients with mild or moderate hepatic impairment. Corlanor is contraindicated in patients with severe hepatic impairment (Child-Pugh C) as it has not been studied in this population and an increase in systemic exposure is anticipated [see Contraindications (4) and Clinical Pharmacology (12.3)]. 8.7 Renal Impairment No dosage adjustment is required for patients with creatinine clearance 15 to 60 mL/min. No data are available for patients with creatinine clearance below 15 mL/min [see Clinical Pharmacology (12.3)]. 10. OVERDOSAGE Overdose may lead to severe and prolonged bradycardia. In the event of bradycardia with poor hemodynamic tolerance, temporary cardiac pacing may be required. Supportive treatment, including intravenous (IV) fluids, atropine, and intravenous betastimulating agents such as isoproterenol, may be considered. This Brief Summary is based on the Corlanor® Prescribing Information v1, 04/15 Corlanor® (ivabradine) Manufactured for: Amgen Inc. One Amgen Center Drive Thousand Oaks, California 91320-1799 Patent: http://pat.amgen.com/Corlanor/ © 2015 Amgen Inc. All rights reserved. Not for reproduction. USA-998-108642, v2 08/15 Download the Mobile Meeting Guide 9:15 AM Dashboard Mobile app available at scientificsessions.org/mobile My Schedule Educational Sessions Faculty Abstracts Unofficial Programs Science & Tech Hall Maps Get It At Sessions Sessions Daily News AHA Newsroom Science News Updates Social Networks AHA EVENTS 2015 Use the above QR code to download the meeting guide app now or search and download the app from the Google play or App Store by searching “AHA Events”! ©2015, American Heart Association 8/15DS9611 BIGGER & AMERICAN HEART ASSOCIATION SCIENTIFIC SESSIONS 2015 CUSTOMIZE your experience with tracks. Programming is divided into five main categories: Basic, Clinical, Population, Special Focus and Frontiers in Science. Each category features a number of areas of interest to allow you to focus your education in your specialty or expand your knowledge in other areas. But most important, you will be able to locate what you need faster and more easily than ever before. Basic Science programming seeks to provide state-of-the-art insights into the underlying mechanisms of cardiovascular development and disease. These insights ultimately could lead to the development of effective new interventions to better diagnose, treat and prevent cardiovascular disease. Clinical Science programming aims to provide access to the latest clinical and Use the new areas of interest/tracks scientific applications in the diagnosis, to create a schedule that will make medical management, prevention and treatment of Scientific Sessions the right fit for you. cardiovascular disease. The Population Science programming provides awareness of the most effective population-based approaches to preventing cardiovascular diseases and improving cardiovascular health across populations. The Special Focus programming is comprised of various topics within cardiovascular disease that are of continuing concern to clinicians, including the use of innovative tools and technologies. The Frontiers in Science meetings deliver one-day, science-focused gatherings that provide an intimate setting for the free exchange of new ideas. Speakers present in a rapid-fire format, encouraging discussion throughout the day. Because Frontiers in Science meetings focus on pre-discovery/pre-publication topics, there is no recording of lectures or discussion; ideas are not meant to be disseminated to the public. See the box to the right for a complete list of the categories affiliated with each track. 6 American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org BIG areas of interest/ tracks BASIC •Arteriosclerosis, Vascular Biology and Development • Cardiac Development, Structure and Function • Genetics and Genomics • Metabolism and Physiology • Cellular Biology and Function • Signaling Mechanisms and Drug Discovery • Thrombosis, Immunity and Inflammation CLINICAL • Chronic and Acute Ischemic Heart Disease • Arrhythmias and Electrophysiology • Intervention and Surgery • Heart Failure and Cardiomyopathies •Hypertension •Imaging • Vascular Disease •Stroke • Nursing Clinical Symposium POPULATION • Prevention and Rehabilitation • Obesity and Cardiometabolic Health • Lifestyle Risk Factors • Quality of Care and Outcomes •Epidemiology • Population Health Cohorts – Big Data • Workplace Health • Health Tech SPECIAL FOCUS • Nursing Science • Clinical Trialists • Lifelong Congenital Heart Disease and Heart Health in the Young • Resuscitation Science Symposium FRONTIERS IN SCIENCE •Arrhythmia Research Summit • Vascular Disease & BETTER AMERICAN HEART ASSOCIATION SCIENTIFIC SESSIONS 2015 SESSIONS 2015 HIGHLIGHTS LEARN in the Health Tech sessions. One fee. FULL ACCESS. Health Tech sessions explore the role of technology in the treatment and prevention of cardiovascular disease, examine ways to drive innovation and collaboration in the marketplace and, ultimately, drive toward a health-technology road map with the goal of improved outcomes. Scientific Sessions registration now includes access to more programming: • Arrhythmia Research Summit • Resuscitation Science Symposium • Cardiovascular Nursing Clinical Symposium Health Tech sessions will address many topics, from digital health solutions to implementation. ATTEND Genomics Boot Camp. The Science & Technology Hall will be home to the new Simulation Zone. LEARN in the Simulation Zone. At the Genomics Boot Camp, learn about genomics through case-based, active-learning activities. Test your cardiac knowledge, skills and critical thinking in AHA’s new hands-on, interactive Simulation Zone. PARTICIPATE in the 2015 Guidelines Instructor Conference. Body Interact Body Interact is an immersive training platform that virtualizes acute and chronic medical conditions. Mechanical Circulatory Support Simulation This area of the Simulation Zone provides a hands-on opportunity to model critical scenarios and observe hemodynamic consequences. Attendees who have an interest in learning about clinical genomics, especially non-scientists and clinical practitioners (including physicians, nurses, pharmacists, etc.) are welcome to attend this flipped classroom boot camp. All Genomics Boot Camp participants must complete the Basic Concepts in Genetics and Genomics CME/CE activity on learn.heart.org prior to the event. A certificate of completion must be presented for entry. Don’t miss your opportunity to receive your required Guidelines Instructor update from the AHA at the 2015 Guidelines Instructor Conference on Friday, Nov. 6, prior to Scientific Sessions 2015. Using a conference format, attendees will receive a comprehensive science update, and then add sessions for each discipline. AHA science experts, volunteers and staff will outline what the new guidelines mean for teaching lifesaving CPR and ECC courses. BLS, ACLS and PALS sessions will be offered multiple times throughout the day of the conference. The Guidelines Instructor Conference includes a fourth educational track for instructor development and enrichment. scientificsessions.org | American Heart Association Scientific Sessions 2015 Preview 7 AMERICAN HEART ASSOCIATION SCIENTIFIC SESSIONS 2015 BIG SCIENCE. BIG INNOVATION. BIG DISCOVERIES. More than 17,000 cardiovascular healthcare professionals attended Scientific Sessions last year, including more than 6,000 international attendees who came from more than 100 countries. You asked. We listened. We delivered new offerings and enhanced favorites, giving you more reasons than ever to attend Scientific Sessions 2015. Scientific Sessions 2015 offers a unique opportunity to gather with colleagues from around the world in an exciting educational and professional environment. The scope and quality of the scientific exchange make Scientific Sessions the premier cardiovascular research and educational meeting in the world. BIG science To extend your learning, you can connect with the researchers involved in select trials through the Meet the Trialists program. Located in the Science & Technology Hall, Meet the Trialists provides the opportunity to get your questions answered in a casual setting. BIG clinical simulation Presented in AHA’s newly formed Simulation Zone, located in the Science & Technology Hall, Body Interact is EXPECT Late-Breaking Clinical Trials bring you face-to-face with leading experts in the cardiovascular field as they unveil the latest breakthroughs in clinical science. These innovative presentations likely will have a significant impact on your clinic practice, making them one of the must-see forums at Scientific Sessions. The Clinical Science Special Report sessions highlight trial updates, registries and important clinical science in a variety of specialties. THINGS 8 Learn from the cardiovascular community’s leading presenters at Scientific Sessions 2015. an immersive training platform that virtualizes acute and chronic medical conditions. Experts will facilitate realistic user experiences with a life-like virtual patient, complete with dynamic monitoring, dialoguing, test orders, scans, drugs, intervention options and performance debriefing. The Simulation Zone is also where you’ll find Mechanical Circulatory Support Simulation. The field of mechanical circulatory support provides longer and improved quality of life for patients with end stage heart failure. As innovation in this field impacts an increasing number of patients, new diagnostic dilemmas challenge the clinician. The Mechanical Circulatory Support Simulation — led by industry experts — provides a hands-on opportunity to model critical scenarios and observe hemodynamic consequences. A total artificial heart mock circulatory loop paired with both axial and centrifugal continuous flow devices will test scenarios such as inadequate preload/afterload conditions, right heart failure and device obstruction. American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org AMERICAN HEART ASSOCIATION SCIENTIFIC SESSIONS 2015 BIG TECHNOLOGY. BIG NETWORKING. IT’S ALL HERE. BIG innovation Schedule time to explore the Science & Technology Hall, where you’ll discover the latest in technology, services and products. You will find areas dedicated to the tools and resources for your business and practice. Check out the Cardiovascular Expert Theaters to find specific products and therapeutic treatments, and visit the Emerging Science & Technology Showcase to see the latest technologies in prevention, diagnosis and treatment of cardiovascular disease. BIG technology If you aren’t following Scientific Sessions 2015 on your smartphone or mobile device, you’re missing out. Use the Mobile Meeting Guide app to get instant access to educational sessions, ePosters, abstracts, faculty, event information, hotels, schedule planning and maps. Ask questions and engage with big-name speakers in our most popular sessions live by using the Digital Moderators component. Listen The Mobile Meeting Guide offers instant access to educational sessions, abstracts and more. BIG events Conference Notes Available in more sessions this year, Conference Notes is an app which allows you to follow along with presentations in real time, bookmark important slides to revisit later, and add notes and sketches directly on your screen. Conference Notes is available on iPad or through your internet browser for laptop viewing. Please bring your own iPad or laptop to experience Conference Notes during Sessions 2015. The app is provided by AstraZeneca. Visit with the many exhibitors in the Science & Technology Hall. to live stream audio from all the educational sessions. Navigate the meeting through the interactive map, get information on all the Science & Technology Hall exhibitors, and expand your professional network. Additionally, with easy access to your Scientific Sessions photos, you can quickly share your pictures on social networks. (Follow us on social media using #AHA15.) Never stop learning. In addition to the hundreds of presentations and educational opportunities at Scientific Sessions, you also have access to Unofficial Satellite Events — independently organized scientific and educational activities offered and/or accredited by various sponsoring organizations. These events will be held during Scientific Sessions 2015 before and after official programming, giving you an opportunity for additional learning and networking. BIG information HeartQuarters, located in Booth 859 in the Science & Technology Hall, is your one-stop shop for all things American Heart Association. Here you can join or renew AHA/ASA Professional Membership, learn about councils, browse various scientific publications, explore online professional education activities and attend events in the theater. scientificsessions.org | American Heart Association Scientific Sessions 2015 Preview 9 AMERICAN HEART ASSOCIATION SCIENTIFIC SESSIONS 2015 you to give your feet a break by trading your business shoes for comfortable walking shoes. To ignite your competitive side, we’ll host the Annual Sessions Walking Challenge, which will track your daily steps. The program will feed all numbers into a leaderboard so users can monitor their daily progress and see how they compare to the leading walkers at Sessions. PACKING LIST When packing your bags to come to Scientific Sessions 2015, remember to bring these items: ❏ iPad or laptop — so you can participate in Conference Notes ❏ Sneakers — for Wear Sneakers Day ❏ Red attire — so you can support Wear BIG opportunities Walking is a part of Scientific Sessions. Turn it into something fun by participating in the Walking Challenge. Come see our new layout featuring the Collaboration Station and Shop Heart, as well as Science, Patient and Consumer programs. Our theater will hold hourly presentations. Check out the interactive global map which will allow you to see your colleagues from around that world that are attending Scientific Sessions. BIG fitness Just because you’re traveling doesn’t mean you have to kick your daily exercise routine to the curb. AHA has planned several activities for you. Wear Your Sneakers Day will be Tuesday, Nov. 10, when we invite Early career members are invited to engage with senior investigators at the Early Career Day on Saturday, Nov. 7. The day features an opening general session, a networking lunch and specialty breakout sessions. At the Early Career Engagement Lounge, you can meet the experts, learn how AHA membership can help you achieve your goals, network with peers and see what other attendees are saying on our social media sites. BIG discoveries Don’t miss the cutting-edge original research presented through Posters and ePosters that are displayed in the Poster Hall. You can view these at personal workstations or on your smartphone. You also are encouraged to go online and communicate with presenters via email. Posters presenters will be able to network with Poster Professors — the top researchers in a presenter’s field of interest — who will make rounds to welcome and network with Red for Women Day ❏ Fitness tracker — to track all your steps ❏ Business cards — for networking poster presenters for increased interaction and robust discussion. The Best of AHA Specialty Conferences Poster Session features the top 10 percent of abstracts presented at the 2015 specialty conferences. Meet these poster presenters from 9:30 to 11 a.m., Monday, Nov. 9. An addition to our Poster program is the Basic Science Reception, which recognizes the best of basic science abstracts, as well as late-breaking basic science abstracts. It will be held from 5 to 7 p.m., Monday, Nov. 9. Check out the Case Theaters: Learning at the Movies, presentations that showcase technical aspects and management of procedures performed in patients, accompanied by a panel of experts for intense discussion. The Case Theaters are 45-minute live presentations of case presentations by international experts in challenging and controversial situations in structural heart disorders, cardiac surgery, vascular intervention and advanced heart failure. BIG networking Meet, network and share ideas with colleagues at Scientific Sessions 2015. 10 Scientific Sessions attracts nearly 17,000 attendees, with a global presence from more than 100 countries, making it the perfect place to expand your network and share your knowledge on cardiovascular diseases and stroke with like-minded professionals. Several networking opportunities are available during the week, including Meet the Trialists, Case Theaters: Learning at the Movies, EP Central, Simulation Zone, WiFi/ Charging Lounges, Early Career Lounge, council dinners, as well as the Members Circle and AHA Fellows Lounge. American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org Heart Disease and Stroke Statistics—2015 Update Your only source for verified data on US cardiovascular health Rates of death attributable to cardiovascular diseases (CVD) have declined, yet the burden of disease remains high. Based on 2011 data: • The overall rate of death attributable to CVD was 229.6 per 100,000. • More than 2150 Americans die of CVD each day, an average of 1 death every 40 seconds. • Stroke accounted for ≈1 of every 20 deaths in the United States. Prevalence and control of traditional risk factors remains an issue for many Americans: • 32.6% of US adults have hypertension. That’s 80 million adults. • An estimated 30.9 million adults have total serum cholesterol levels ≥240 mg/dL. • Among adults in the United States, 1 in 5 men and 1 in 6 women are current smokers. Presence of ideal cardiovascular health is age, sex, and race related: • Younger adults are more likely to meet greater numbers of ideal metrics than are older adults. More than 60% of Americans >60 years of age have ≤2 metrics at ideal levels. At any age, women tend to have more metrics at ideal levels than do men. • Blacks and Mexican Americans tend to have fewer metrics at ideal levels than whites or other races. Approximately 6 in 10 white adults and 7 in 10 black or Mexican American adults have no more than 3 of 7 metrics at ideal levels. Visit circ.ahajournals.org/site/StatUpdate to link to the full-text article. Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, de Ferranti S, Després J-P, Fullerton HJ, Howard VJ, Huffman MD, Judd SE, Kissela BM, Lackland DT, Lichtman JH, Lisabeth LD, Liu S, Mackey RH, Matchar DB, McGuire DK, Mohler ER 3rd, Moy CS, Muntner P, Mussolino ME, Nasir K, Neumar RW, Nichol G, Palaniappan L, Pandey DK, Reeves MJ, Rodriguez CJ, Sorlie PD, Stein J, Towfighi A, Turan TN, Virani SS, Willey JZ, Woo D, Yeh RW, Turner MB; on behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics—2015 update: a report from the American Heart Association. Circulation. 2015;131:e29–e322. doi: 10.1161/CIR.0000000000000152. 5-Q001 AMERICAN HEART ASSOCIATION SCIENTIFIC SESSIONS 2015 SCIENTIFIC SESSIONS Nov 7 Saturday 7:00 8:00 9:00 Sunday 8 11:00 12:00 1:00 Early Career Day Includes a general session, specialty breakouts (including the Peripheral Vascular Disease FIT Workshop) and a reception for all. Invited Sessions Nov 10:00 Lunch Break Science & Technology Exhibit Hall Opening Session Poster Sessions Nov 10 Nov 11 Wear Sneakers Day 9 Wednesday Nov Wear Red Day Science & Technology Exhibit Hall Invited Sessions Late-Breaking Clinical Trials and Invited Sessions Oral Abstracts Oral Abstracts Lunch Break Science & Technology Exhibit Hall Poster Sessions Science & Technology Exhibit Hall Invited Sessions Late-Breaking Clinical Trials and Invited Sessions Oral Abstracts Oral Abstracts Lunch Break Science & Technology Exhibit Hall Poster Sessions Science & Technology Exhibit Hall Invited Sessions Don’t Miss Out on These Other Key Events Invited Sessions and Late-Breaking Clinical Trials Sa Su M Resuscitation Science Symposium Saturday-Monday Nov. 7-9 M Frontiers in Science: Arrhythmia Research Summit Monday Nov. 9 12 American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org AMERICAN HEART ASSOCIATION SCIENTIFIC SESSIONS 2015 WEEK AT-A-GLANCE 2:00 3:00 4:00 5:00 Late-Breaking Clinical Trials and Invited Sessions 6:00 7:00 Invited Sessions Oral Abstracts Oral Abstracts Invited Sessions Invited Sessions Invited Sessions Oral Abstracts Oral Abstracts Oral Abstracts Invited Sessions Invited Sessions Invited Sessions Oral Abstracts Oral Abstracts Oral Abstracts Council Dinners Rosen Center Orlando, Florida M Frontiers in Science: Vascular Disease M Tu Health Tech Monday Nov. 9 Monday Nov. 9 M Tu Clinical Nursing Symposium Monday-Tuesday Nov. 9-10 Workplace Health Monday Nov. 9 Tu Clinical Trialists Tuesday Nov. 10 scientificsessions.org | American Heart Association Scientific Sessions 2015 Preview 13 ADVANCE PROGRAM AND FACULTY LATE-BREAKING CLINICAL TRIALS AND LATE-BREAKING CLINICAL TRIALS SUNDAY, NOV. 8 Oral sGC Stimulator Vericiguat in Patients With Worsening Chronic Heart Failure and Reduced Ejection Fraction — The SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with REDUCED EF (SOCRATES-REDUCED) Study SOCRATES-REDUCED: Phase II dose finding LBCT.01, 3:45-5 p.m. trial of the once daily sGC stimulator vericiguat Failure is Not an Option: New Drugs and Systems of Care added to standard therapy in patients with worsening chronic HF and reduced ejection fraction over 12 weeks. A Randomized Trial of Liraglutide for High-Risk Heart Failure Patients With Reduced Ejection Fraction controlled clinical trial of treatment with Remote Patient Management After Discharge of Hospitalized Heart Failure Patients: The Better Effectiveness After Transition — Heart Failure Study liraglutide versus placebo for six months in high- BEAT-HF: The Better Effectiveness After risk HF patients with reduced ejection fraction Transition — Heart Failure (BEAT-HF) study is a (LVEF ≤ 40 percent) and recent hospitalization. comparative effectiveness randomized control FIGHT: A randomized, double-blinded, placebo- trial that evaluated a remote patient management Nitrate’s Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction (NEAT-HFpEF) NEAT-HFpEF: This trial was designed to evaluate MONDAY, NOV. 9 care transition approach to reduce readmissions for 1,404 hospitalized heart failure patients aged LBCT.02, 10:45-11:55 a.m. 50 years and over. Decreasing the Global Burden of Disease: Breakthroughs in Prevention the effect of isosorbide mononitrate on activity tolerance in heart failure with preserved ejection fraction. The Efficacy and Safety of Varenicline, a Selective Alpha4beta2 Nicotinic Receptor Partial Agonist, for Smoking Cessation in Patients Hospitalized With Acute Coronary Syndrome: A Randomized Controlled Trial E VITA: This trial was designed to evaluate the efficacy and safety of varenicline for smoking cessation in patients hospitalized with acute coronary syndrome. 14 American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org ADVANCE PROGRAM AND FACULTY CLINICAL SCIENCE SPECIAL REPORTS Clinical Trial of a Mobile Health Intervention for Simultaneous Versus Sequential Diet and Activity Change Clinical Outcomes of Intravascular Ultrasound Guided Everolimus-Eluting Stents Implantation in Long Coronary Lesions MBC2: Make Better Choices 2 is a mobile health IVUSXPL: During the PCI procedure, trial designed to determine whether targeting intravascular ultrasound (IVUS) is a useful tool for diet and activity risk behaviors simultaneously or providing information on pre-intervention lesion sequentially maximized healthy lifestyle change. characteristics and post-intervention optimal stent implantation. Although recent guidelines The Effect of Disclosing Genomic Risk of Coronary Heart Disease on Low-Density Lipoprotein Cholesterol Levels: The Myocardial Infarction Genes (MI-GENES) Study recommend the use of IVUS to optimize stent MI-GENES: Individuals who received a genetic remains uncertain because of the limited number risk score for coronary heart disease had of properly powered randomized studies. In significantly lower LDL-C levels than participants addition, although first-generation DESs were who received a conventional risk score. commonly used in most studies for investigating Knowledge of genetic risk of coronary heart the IVUS-guided DES implantation, second- disease may have clinical utility. generation DESs are exclusively used for PCI implantation for select patients, the impact of IVUS-guided drug-eluting stent (DES) implantation on improved clinical outcomes in current clinical practice, and determining Empagliflozin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus at High Cardiovascular Risk the clinical usefulness of IVUS-guidance in the EMPA-REG OUTCOME: This trial is the clinical benefit of IVUS-guidance in second- frontrunner and first-in-class CV outcome trial generation DES implantation in an adequately in type 2 diabetes involving an SGLT-2 inhibitor powered randomized clinical trial. implantation of these DESs is also required. The current study is the first demonstration of the Impact of a Comprehensive Lifestyle PeerGroup-Based Intervention on Cardiovascular Risk Factors: A Randomized Controlled Trial (empagliflozin). Fifty-Fifty Program: The aim of the Fifty-Fifty TUESDAY, NOV. 10 PEGASUS-TIMI 54: This was a trial designed multicenter community-based comprehensive LBCT.03, 10:45 a.m.-12:10 p.m. with two dosing strategies for chronic secondary lifestyle intervention for the self-control of ACS and PCI: The Continuum of Care prevention. Program was to evaluate the impact of a Long-Term Tolerability of Ticagrelor in the PEGASUS-TIMI 54 Trial to evaluate the efficacy and safety of ticagrelor cardiovascular risk factor through peer-group dynamics. Providing Rapid Out of Hospital Acute Cardiovascular Treatment (PROACT-4) PROACT-4: This trial was designed to test the addition of point-of-care troponin testing in the ambulance for patients with chest pain. Funded by the Heart and Stroke Foundation Canada. While every effort is made to ensure the accuracy of data within this publication, the publisher cannot be held responsible for errors or omissions. Data current as of Aug. 25, 2015. scientificsessions.org | American Heart Association Scientific Sessions 2015 Preview 15 ADVANCE PROGRAM AND FACULTY Individualizing Treatment Duration of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention: An Analysis of the DAPT Study DAPT: The Dual Antiplatelet Therapy Study Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA): Primary Results of a Randomized, 2 x 2 Factorial, Placebo-Controlled, Double-Blind Clinical Trial was an international, multicenter, double- PRADA: This randomized, placebo-controlled, blind, randomized trial that investigated the double-blind trial assessed the effect of the ALN-PCSsc, an RNAi Investigational Agent That Inhibits PCSK9 With Potential for Effective Quarterly or Possibly Bi-Annual Dosing: Results of Single-Blind, Placebo-Controlled, Phase 1 Single-Ascending Dose (SAD), and Multi-Dose (MD) Trial in Adults With Elevated LDL-C, on and off Statins benefits and risks of 30 versus 12 months of beta blocker metoprolol and the angiotensin ALN-PCSsc: An RNAi investigational agent dual antiplatelet therapy in patients undergoing receptor blocker candesartan as preventive that inhibits PCSK9 with potential for effective percutaneous coronary intervention with drug- cardioprotective therapy in women treated with quarterly or possibly bi-annual dosing. eluting or bare metal stents. an anthracycline-containing early adjuvant breast cancer regimen with or without trastuzumab and Angina and Quality of Life Following PCI With Incomplete Revascularization: Results From the Ranolazine for Incomplete Vessel Revascularization (RIVER-PCI) Trial radiation. CLINICAL SCIENCE SPECIAL REPORTS placebo, and followed them for ischemia- ANNEXA-R Part 2: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial Demonstrating Sustained Reversal of Rivaroxaban-Induced Anticoagulation in Older Subjects by Andexanet Alfa (PRT064445), a Universal Antidote for Factor XA (FXA) Inhibitors driven hospitalization or revascularization and ANNEXA-R: Andexanet Alfa a Novel Antidote CS.01, 9-10:15 a.m. patient-reported angina and quality of life during to the Anticoagulant Effects of fXA Inhibitors – follow-up. Rivaroxaban: ANNEXATM is a four-part, Phase Novel Findings From Next Generation Registries RIVER-PCI: This trial randomized patients with a history of angina and incomplete revascularization after PCI to ranolazine or MONDAY, NOV. 9 3, double-blind, placebo-controlled program WEDNESDAY, NOV. 11 subjects treated with rivaroxaban or apixaban; LBCT.04, 10:45 a.m.-12:15 p.m. AnXa followed by a two-hour continuous infusion Increased Incidence of Infective Endocarditis After the 2009 European Society of Cardiology Guideline Update: A Nationwide Study in the Netherlands Novel Therapies for Common Problems will be presented. This is the first nationwide study evaluating the One Year Follow-up Results From AUGMENT-HF: A Multicenter Randomized Controlled Clinical Trial of the Efficacy of Left Ventricular Augmentation With Algisyl-LVR in the Treatment of Heart Failure Prevention of Acute Kidney Injury by Nitric Oxide During and After Prolonged Cardiopulmonary Bypass. A Double Blind Randomized Controlled Trial guidelines on the prevention, diagnosis and NITRIC: Nitric Oxide was delivered during and One year follow-up results from AUGMENT-HF: after prolonged cardio-pulmonary bypass to A multicenter, randomized, controlled clinical prevent acute kidney injury caused by plasma- trial testing a novel heart failure therapy as a Hb induced NO scavenging. Examining Prevailing Genotype-Phenotype Correlations in Hypertrophic Cardiomyopathy: Findings From the Sarcomeric Human Cardiomyopathy Registry (SHaRe) comprised of two studies of AnXa in older ANNEXA-R Part 2 which investigated a bolus of updated 2009 European Society of Cardiology The-First-in-Man Randomized Trial of a ß3adrenoceptor Agonist in Chronic Heart Failure — the BEAT-HF Trial recommendations. SHARE: The Sarcomeric Human Cardiomyopathy potentially effective treatment for patients with advanced HF. treatment of infective endocarditis prophylaxis A Randomized, Placebo Controlled Trial of Late Na Channel Inhibition (ranolazine) in Coronary Microvascular Dysfunction (CMD): Impact on Angina and Myocardial Ischemia Registry (SHaRe) was established to amass RWISE: We conducted a randomized, double- robust large-scale, longitudinal genotype, phenotype and outcomes data for HCM. BEAT-HF: This trial was designed to evaluate the blinded, placebo-controlled, crossover trial of effect on heart pump function and safety of a oral ranolazine 500-1,000 mg twice daily for two beta 3 receptor agonist in patients with chronic weeks in women and men with symptoms and The Impact of the Appropriate Use Criteria on Patient Selection and Appropriateness of Percutaneous Coronary Intervention — Findings From the NCDR-CathPCI Registry heart failure. signs of myocardial ischemia, no obstructive Assessing the impact of the appropriate use CAD and abnormal CFR or abnormal myocardial criteria on appropriateness of PCI between July perfusion reserve index (MPRI) on CMRI. 2009 and December 2014. 16 American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org ADVANCE PROGRAM AND FACULTY Clopidogrel on Top of Aspirin for the Prevention of New-Onset Migraine Headache Attacks Following Transcatheter Closure of Atrial Septal Defects: A Prospective, Randomized, Double Blind Trial (CANOA) CANOA: This trial was designed to evaluate the efficacy of clopidogrel on top of aspirin for the prevention of migraine attacks following atrial septal defect closure. MONDAY, NOV. 9 CS.02. 3:45-5:05 p.m. Cutting-Edge Technologies in EP Cardiac Resynchronization Therapy Is Detrimental in Patients With QRS Duration Greater Than 180ms and Right Bundle Branch Block Morphology: Analysis From the Medicare ICD Registry Cardiac resynchronization therapy is detrimental in patients with QRS duration greater than 180ms and right bundle branch block morphology. Four Late-Breaking Clinical Trials sessions and three Clinical Science Special Reports sessions will be presented during Scientific Sessions 2015. Analysis from the Medicare ICD registry. Miniaturized Transcatheter Delivered Cardiac Pacing: Primary Results of a Worldwide Clinical Trial TUESDAY, NOV. 10 The purpose of this clinical study was to Managing Risk Factors for CAD — Clinical Trial Updates evaluate the safety and efficacy of the Micra CS.03, 3:45-5:03 p.m. Long-Term Cardiovascular Effects of 4.9 Years of Intensive Blood Pressure Control in Type 2 Diabetes Mellitus: The Action to Control Cardiovascular Risk in Diabetes Follow-on Blood Pressure Study ACCORDION Follow-on BP Study: This study Transcatheter Pacing System and to assess long-term performance. Cholesterol Treatment Targets and Clinical Outcomes: A JUPITER Trial Update assessed the long-term (10-year) effect of 4.9 A Randomized Controlled Trial of a Video Decision Support Tool to Depict Goals of Care and Resuscitation Options for Patients With Advanced Heart Failure JUPITER: This analysis of the completed (<140 mm Hg) systolic blood pressure lowering JUPITER trial addresses whether or not on- on the incidence of cardiovascular events or treatment target levels of LDLC, non-HDLC death in 4733 people with type 2 diabetes and and apo B are relevant for event reductions high cardiovascular risk. This trial is a randomized controlled trial evaluating attributable to statin therapy, an issue relevant the impact of a goals-of-care video decision for current guidelines. support tool on decisions regarding CPR/ Peri-Procedural Safety of Left Atrial Appendage Occlusion With the WATCHMAN Device. Preliminary Data From the EWOLUTION Registry Relationship Between High-Density Lipoprotein Cholesterol and Cardiovascular and NonCardiovascular Mortality: A Population-Based Study of More Than 630,000 Individuals Without Prior Cardiovascular Conditions in Ontario, Canada EWOLUTION: This prospective registry aimed to Canheart (CArdiovascular HEalth in Ambulatory obtain data on real world efficacy and safety of Care Research Team): A team that leverages big Watchman LAA occlusion. data to improve the outpatient care provided to intubation for patients with advanced heart failure. years of intensive (<120 mm Hg) versus standard Revascularization in Patients With Diabetes and Multivessel Coronary Artery Disease: A Population-Based Evaluation of Outcomes Results from a real-world experience in revascularization of patients with diabetes and multivessel coronary disease from British Columbia. patients with cardiovascular risk factors and/or chronic conditions. While every effort is made to ensure the accuracy of data within this publication, the publisher cannot be held responsible for errors or omissions. Data current as of Aug. 25, 2015. scientificsessions.org | American Heart Association Scientific Sessions 2015 Preview 17 PROFESSION A L M E M B E R S HI P my.americanheart.org Whether you are an early career member looking to learn and grow in your specialty, or a FAHA looking to broaden your leadership opportunities, there are unique AHA Professional Membership benefits that are tailored to you and your career stage. P RO FE SSIONAL ME MB E R SHIP BENEFITS INCLUDE:* • Up to $400 in savings on Scientific Sessions 2015 registration — plus registration savings at AHA’s other scientific conferences. • Complimentary access to Sessions OnDemand.TM • Benefits that extend beyond science so you can contribute to AHA’s mission of building healthier lives, free of cardiovascular diseases and stroke. • Unprecedented access to research and clinical information across multiple specialties. • Be a part of our AHA Professional Online Network — connect with peers and leaders in your specialty. • The research grant application fee is waived for members. You can apply at my.americanheart.org/research. • Online access to AHA Scientific journals (full text). We’re proud that our membership includes more than 7,300 international professionals, in more than 128 countries outside the United States, dedicated to our mission of building healthier lives, free of cardiovascular diseases and stroke. Become part of a huge network making a global impact on the fight against cardiovascular diseases and stroke. We couldn’t fight this fight without you. Visit our staff at HeartQuarters in the Science & Technology Hall, Booth 859 * Benefits depend on membership tier. to learn more about the benefits of professional membership and join our network of almost 33,000 members today. ©2015, American Heart Association 8/15DS96033 ADVANCE PROGRAM AND FACULTY SCIENTIFIC PROGRAMMING ABSTRACT ORAL SESSIONS Keith A. Fox, BSC, MB, ChB, FESC, FRCP Edinburgh, United Kingdom Got questions? Get answers during these sessions, which allow you to interact with the presenter and generate meaningful discussion. Abstract Oral Sessions will have 15 minutes allotted for each abstract presenter (10 minutes presentation followed by five minutes of questions and answers). Early Career Investigator Award Sessions will recognize promising and outstanding investigators in the early stages of their careers, stimulate continued interest in basic or clinical research and help early career investigators participate in AHA meetings. Featured Research Sessions will offer state-of-the-science lectures on compelling areas of research. Speakers in this category have not only made outstanding contributions to the field, but are also talented teachers and communicators. Named Lectures/Council-sponsored lectures are presented throughout the meeting in honor of scientists and AHA volunteers who have made outstanding contributions to the field and the American Heart Association. Lasker Laureate Lecture ABSTRACT POSTER SESSIONS Alain Carpentier, MD, PhD Paris Don’t pass up the Poster Sessions in Poster Hall. You can view them Sunday, Nov. 8 through Tuesday, Nov. 10. Want more information? Meet with the authors from 9 to 10:15 a.m., 2 to 3:15 p.m. or 5:30 to 6:45 p.m., Sunday, Nov. 8, through Tuesday, Nov. 10, with Poster Professors making rounds to meet authors for increased interaction and robust discussion. SPECIAL LECTURES Presidential Address Mark A. Creager, MD, FAHA Lebanon, New Hampshire Lewis A. Conner Memorial Lecture Andrew Conrad, PhD San Francisco Paul Dudley White International Lecture Distinguished Scientist Lecture Christine Seidman, MD, FAHA Boston Keynote Address by the Director of the National Institutes of Health Francis S. Collins, MD, PhD Bethesda, Maryland 20 EARLY CAREER PROGRAMMING SATURDAY, NOV. 7 9 a.m.-Noon General Session 11:45 a.m.-12:45 p.m. Complimentary lunch sponsored by AHA/ ASA membership 1-5 p.m. Specialty Science Breakouts (including the PVD FIT Workshop, 9 a.m.-5 p.m.) 5-6:30 p.m. Reception CLINICAL SCIENCE SPECIAL REPORTS See pages 16-17 for details. MONDAY, NOV. 9 Novel Findings From Next Generation Registries CS.01 Cutting-Edge Technologies in EP CS.02 TUESDAY, NOV. 10 Managing Risk Factors for CAD — Clinical Trial Updates CS.03 More than 800 sessions will be presented at Scientific Sessions 2015. American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org ADVANCE PROGRAM AND FACULTY LATE-BREAKING CLINICAL TRIALS See pages 14-16 for details. BIG IDEAS: 30 AREAS OF INTEREST/TRACKS SUNDAY, NOV. 8 Basic Population Failure is Not an Option: New Drugs and Systems of Care LBCT.01 Arteriosclerosis, Vascular Biology and Development Cardiac Development, Structure and Function Genetics and Genomics Metabolism and Physiology Cellular Biology and Function Signaling Mechanisms and Drug Discovery Thrombosis, Immunity and Inflammation Prevention and Rehabilitation Obesity and Cardiometabolic Health Lifestyle Risk Factors and Behavior Change Quality of Care and Outcomes Epidemiology Population Health Cohorts - Big Data Workplace Health Health Tech MONDAY, NOV. 9 Decreasing the Global Burden of Disease: Breakthroughs in Prevention LBCT.02 TUESDAY, NOV. 10 ACS and PCI: The Continuum of Care LBCT.03 WEDNESDAY, NOV. 11 Novel Therapies for Common Problems LBCT.04 MEET THE TRIALISTS MONDAY, NOV. 9 Clinical Chronic and Acute Ischemic Heart Disease Arrythmias and Electrophysiology Intervention and Surgery Heart Failure and Cardiomyopathies Hypertension Imaging Vascular Disease Stroke Nursing Clinical Symposium Special Focus Nursing Science Clinical Trialists Lifelong CHD and Heart Health in the Young Resuscitation Science Symposium Frontiers in Science Arrhythmia Research Summit Vascular Disease TUESDAY, NOV. 10 OPENING SESSION WEDNESDAY, NOV. 11 SUNDAY, NOV. 8 Navigating the Complex Landscape of Heart Failure PS.09 Opening Session OPS.01 PLENARY SESSIONS SUNDAY, NOV. 8 Affordable Care Act Effects on Patients, Clinicians and Scientists PS.01 MONDAY, NOV. 9 Endovascular Stroke Therapy Trials Update 2015 PS.05 Therapeutic Decisions in Non-ST Elevation Myocardial Infarction PS.02 What Is the Role of Nonstatins in the Statin Era? PS.03 Clinical Care Across the Age Continuum: Creating Bridges to Improve Care and Outcomes from Age 0-100 SS.11 Genetics in Clinical Practice SS.09 SPECIAL SESSIONS Hypertension and Diabetes Mellitus: The Foundation of Both Heart and Kidney Disease SUNDAY, NOV. 8 SS.07 Advances in Structural Heart Disease Interventions for the Clinician SS.01 Precision Medicine SS.08 MONDAY, NOV. 9 Addressing Atherosclerotic Risk in the Under-40 Crowd: Gaps in Guidelines and Gaps in Care SS.02 Cardiovascular Disease Health Disparities in African-Americans, Hispanics and Rural Populations SS.06 Distinguished Scientist Lecture SS.10 WEDNESDAY, NOV. 11 Joint Session AHA/WHO — 10 Years to WHO 2025 Goals: Where Do We Stand? How Far to Go? SS.13 Updated Implementation of Multimodality Imaging Based on Guidelines (Joint Session with European Society of Cardiology) SS.12 Artificial Hearts: Lasker Awardee Lecture SS.04 TUESDAY, NOV. 10 Atrial Fibrillation: State of the Art and Future Direction PS.06 Improving Outcomes in Women’s Cardiovascular Health PS.08 Plaque Vulnerability, Imaging and Cardiovascular Risk: The Bedside Meets the Bench PS.07 Resuscitation Guidelines 2015 PS.04 While every effort is made to ensure the accuracy of data within this publication, the publisher cannot be held responsible for errors or omissions. Data current as of Aug. 25, 2015. Sex-Based Differences in Cardiovascular Disease SS.03 TO BE CONTINUED: CME/CE Solving the Myocyte Loss Problem in Heart Failure SS.05 Physicians, physician assistants, nurses and pharmacists may apply for continuing medical education accreditation. There is no fee for CME/ CE credits. For complete CME/CE accreditation information for Scientific Sessions 2015, visit learn.heart.org. TUESDAY, NOV. 10 Best of Other Cardiovascular Meetings (Domestic and International) SS.14 scientificsessions.org | American Heart Association Scientific Sessions 2015 Preview 21 ADVANCE PROGRAM AND FACULTY SPEAKERS MEET THE 2015 FACULTY A Keith D. Aaronson Antonio Abbate Brian Abbott J. Dawn Abbott Maha Abdellatif Jun-Ichi Abe Willie Mae Abel Benjamin S. Abella Victor Aboyans William T. Abraham Cathie Abrahamsen Dominic Abrams Hugues Abriel Mazen Abu-fadel Michael A. Acker Michael J. Ackerman Jasimuddin Ahamed Tariq Ahmad Xun Ai Ernesto A. Aiello Elena Aikawa Masanori Aikawa Teiji Akagi Fadi G. Akar Shahab A. Akhter Sana Al Khatib Christine Albert Nancy Albert Ryan Aleong 22 Sheila Alexander Thomas Alexander Larry A. Allen Norrina B. Allen Matthew A. Allison Christopher Almond Adah Almutairi Joseph S. Alpert Ahmed AlSayed Salomon Amar Amrut Ambardekar Inder S. Anand CIndy Anderson Jeffrey Anderson Mark E. Anderson Dean Andropoulos Stefan D. Anker Elad Anter Elliott Antman Charalambos Antoniades Ani Anyanwu Lawrence J. Appel Susan E. Appt Christina Aquilante Jayashin Aragam Jesus A. Araujo Stephen Archer Amer K. Ardati Reza Ardehali Ross Arena Hermenegild Arevalo Luisa I. Arispe Aimee Armstrong Paul W. Armstrong Donna Arnett Suzanne V. Arnold Herbert Aronow Pankaj Arora Rakesh Arora Kent Arrell Nancy Artinian Takayuki Asahara Alfred A. AsanteKorang Susan Ashcraft Euan Ashley Houman Ashrafian Stella Aslibekyan Dianne L. Atkins Tom Aufderheide Eric Austin Alberto Avolio B Andrea Baccarelli Emile Bacha Carl L. Backer Leonard L. Bailey Steven R. Bailey Noel C. Bairey-Merz Tamilyn Bakas Andrew Baker Gary J. Balady Ravi C. Balijepalli Christie M. Ballantyne Jean Luc Balligand Sripal Bangalore Gust H. Bardy Susan A. Barnason Geoffrey Barnes Tracie A. Barnett Taura L. Barr Gregory W. Barsness Philip Barter Jerry Bartholomew John Bass Cristina Basso Eric R. Bates Mary E. Bauman Iris Baumgartner William A. Baumgartner Anthony Bavry Jeroen Bax Rob Beanlands Lance Becker Theresa Beckie Joshua A. Beckman Elijah R. Behr Amber Beitelshees John F. Beltrame Frank Bengel Emelia Benjamin Martin Bennett Rhonda Bentley-Lewis Omer Berenfeld Peter Berger Jarett D. Berry Donald M. Bers Stefan Bertog Luc Bertrand Olivier Bertrand Charles I. Berul Hiram G. Bezerra Aruni Bhatnagar Deepak Bhatt Kirsten BibbinsDomingo Charles Billington Joyce Bischoff Gianluigi Bisleri Malenka M. Bissell Vera Bittner Steven Blair Philipp Blanke Ron Blankstein Burns Blaxall Nico A. Blom Gerald S. Bloomfield David A. Bluemke Elizabeth Blume Roger Blumenthal Edimar A. Bocchi William E. Boden Harm Bogaard Michael Bohm Roberto Bolli Marc Bonaca Raoul Bonan Sebastien Bonnet Robert O. Bonow Munir Boodhwani Reinier Boon William B. Borden Michael Borger Madeleen Bosma Zeljko J. Bosnjak Eduardo Bossone Kristina L. Bostrom Rene Botnar Teodoro Bottiglieri Rebecca Boxer Biykem Bozkurt Johannes Brachmann Steven M. Bradley Lisa C. Bratzke American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org Lynne Braun Thomas Braun Eugene Braunwald Mary Brennan Mary Brethour H. Bryan Brewer Luke P. Brewster Emmanouil Brilakis Ralph Brindis Volker Brinkmann Meredith Brisco Michael R. Bristow Thomas G. Brott David Brown Joan Heller Brown W. Virgil Brown Michael A. Brownlee Gerd Brunner Gil Bub Chiara BucciarelliDucci Raffaele Bugiardini Eileen Bulger Thomas Bunch Henning Bundgaard Allen Burke Gregory L. Burke Lora E. Burke John C. Burnett Jane C. Burns Francesco Burzotta Cheryl Bushnell Jonathan T. Butcher Javed Butler Peter M. Buttrick Alfred Buxton Emmanuel S. Buys Barry J. Byrne C Antonio G. Cabrera Linda Cai Laura Calabresi Christopher Caldarone Colleen Caleshu Robert M. Califf Hugh Calkins Clifton W. Callaway John Calvert Duke Cameron John Camm Janet Campbell Lee Ann Campbell Matthew J. Campen ADVANCE PROGRAM AND FACULTY Umberto Campia Thomas Cappola Blase A. Carabello Shemy Carasso Teresa Carithers Lena M.S. Carlsson S. Thomas Carmichael Mercedes Carnethon Melinda J. Carrington Jo Ann Carson Ana I. Casanegra Alberico Catapano Mark Caulfield Scott Ceresnak Marina Cerrone K. M. John Chan Mark Y. Chan Stephen Chan Vincent Chan Nisha ChandraStrobos Ching-pin Chang Richard Channick Keith M. Channon Mark J. Chappell Mark Chappell Panithaya Chareonthaitawee Seemant Chaturvedi Edward Chen Eugene Chen Jaunian Chen Jonathan Chen Ju Chen Ming Hui Chen Peng-Sheng Chen Shih-Ann Chen Shiyou Chen Songcang Chen Yabing Chen Nipavan Chiamvimonvat Alaide Chieffo William Chilian Julio Chirinos W. Randolph Chitwood Jaehyung Cho Byoung Wook Choi Robin Choudhury Benjamin Chow Sheryl L. Chow Sumita Chowdhury Catherine Christie Kabrhel Christopher Sumeet Chugh Data current as of Aug. 20, 2015. Hyung J. Chun Mina Chung Timothy Church Deborah Chyun Eugenio Cingolani Allison Cirino John M. Clark John Cleland James F. Cnota David Cohen Mauricio Cohen William E. Cohn Lola Coke Steven D. Colan Henry M. Colecraft Helen Colhoun Sheila Collins Monica Colvin Anthony Comerota Gianluigi Condorelli Stuart Connolly Michael S. Conte Jennifer Lynn Cook Nancy R. Cook Daniel H. Cooper Marco Costa Maria Rosa Costanzo John M. Costello Bernard Cosyns Thais Coutino Jessica Coviello Chad Cowan Mark A. Creager Andrew Crean Maria G. Crespo-Leiro Alain Cribier Michael H. Criqui Rosanne M. Crooke Bettina F. Cuneo Anne B. Curtis Jeptha Curtis Mary Cushman William C. Cushman Christopher Cutler Donald E. Cutlip Richard J. Czosek D Lisa C. D’Alessandro Sinan Dagdelen Ronald L. Dalman Nicolas Danchin Stephen Daniels Alejandro Dapelo Aste Dawood Darbar Saumya Das Patricia Davidson Leslie L. Davis Michael E. Davis Peter Davis John Day Sharlene M. Day Sanjana Dayal Mark De Caestecker Sarah De Ferranti Vinicio De Jesus Perez Michel de Lorgeril Frances de Man Guido de Meyer Paola De Rango Menno De Winther Steven Dean Arjun Deb Stephanie Debette Prakash Deedwania Emil Degoma Diego Delgado Victoria Delgado Brian Delisle Paolo Della Bella Mario Delmar Donald R. Dengel Ali Denktas Cheryl DennisonHimmelfarb Rahul C. Deo Genevieve Derumeaux Matthias Derwall Akshay Desai Milind Desai Sumbul Desai Jean-Pierre Després Anita Deswal Richard Devereux Cameron Dezfulian Marcelo Di Carli Victoria Dickson Javier Díez Vasken Dilsizian Stefanie Dimmeler Paul DiMusto Ming Ding Sanjay Dixit Ibrahim Domian J. Kevin Donahue Erwan Donal Sharmila Dorbala Pamela S. Douglas James Douketis Michael Dowling Douglas Drachman Konstantinos Drosatos Xiaoping Du Anne Dubin Gregory Ducrocq Jonathan Dukes Shannon M. Dunlay Daniel Duprez Elizabeth Durmowicz Jason Dyck Victor J. Dzau E Kim A. Eagle Matthew J. Eagleton Zubin Eapen Jo-Ann Eastwood Ray Ebert Robert H. Eckel Thor Edvardsen Philip Efron Andrew Einstein David Eisner Sanne Eken Mohammed El Deeb Gebrine El Khoury Mikhael F. El-Chami Patrick T. Ellinor Perry Elliott John W. Elrod Maurice Enriquez Sarano Chris Ensor Slava Epelman Andrew E. Epstein Raimund Erbel David Erlinge Laura Ernande Sabine Ernst Georg Ertl Mark Eskandari Murray Esler Paul Estabrooks N.A. Mark Estes Anthony Estrera Michael Ezekowitz F Alik Farber Peter Faries Michael E. Farkouh David P. Faxon Zahi Fayad William Fearon Paul W. Fedak Francesco Fedele Vadim Fedorov Kathleen Fedyszen Richard Feifer Ross Feldman G. Michael Felker Timothy J. Fendler Michelle Fennessy Brian A. Ference Jane F. Ferguson Victor A. Ferrari Gerasimos S. Filippatos Michael Fischbein Anne F. Fish Glenn Fishman Robert C. Flaumenhaft Kirsten Fleischmann Craig E. Fleishman Barbara Fletcher Gerald F. Fletcher Mark A. Fogel Alan M. Fogelman Gregg C. Fonarow Roger Foo Randi Foraker Thomas Force Paul R. Forfia Daniel E. Forman Gary Foster Keith A. Fox Gary S. Francis Gordon Francis Sheila Francis Katrien Francois Nikolaos Frangogiannis Sarah Franklin Stefan Frantz Julie Freed Kenneth E. Freedland Jane E. Freedman Roy Freeman Stephen Fremes Norbert Frey Mark Friedberg James Froehlich Peter C. Frommelt Toshiro Fujita Keiichi Fukuda Shota Fukuda David R. Fulton John W. Funder Karen L. Furie Valentin Fuster G Michael Gaies Maurizio Galderisi Nazzareno Galie Santhi Ganesh Peter Ganz Hasan Garan Madalina Garbi Jose Garcia Andrew Gardner Anna Gawlinski J William Gaynor Michael Gaziano Frederic Geissmann Caroline A. Genco Alfred L. George Richard George LIor Gepstein Bernard J. Gersh Hertzel Gerstein Robert Gerszten Tal Geva Nancy Ghanayem Joanna Ghobrial Cecilia M. Giachelli Jorge F. Giani Jonathan Gibbins Gary H. Gibbons Michael C. Gibbons Samuel S. Gidding Therese Giglia Martine Gilard Ian Gilchrist Linda D. Gillam Thierry C. Gillebert Thomas Gillette Dan Gilon Mark Gladwin Andrew C. Glatz Christopher Glembotski Michael Glikson David Glineur Alan S. Go Ron Goetzel David C. Goff Michael R. Gold Anne C. Goldberg Ira J. Goldberg Lee R. Goldberg Jeffrey Goldberger scientificsessions.org | American Heart Association Scientific Sessions 2015 Preview 23 ADVANCE PROGRAM AND FACULTY Joshua I. Goldhaber Samuel Z. Goldhaber Larry B. Goldstein Michael Gollob Ramon Gonzalez Juanatey Holly C. Gooding Sarah Goodlin Philip Gordts Philip R. Gorelick Bulent Gorenek Heather Gornik Robi Goswami John S. Gottdiener K. Lance Gould Andrew Grace Kathleen L. Grady Eric M. Graham Christopher B. Granger Henk Granzier WIlliam Gray Barry H. Greenberg John Greenwood Igor Gregoric Hendrik Gremmels Steven Grinspoon Leanne Groban Lars GrosseWortmann Claudia Grossmann Jessica Grossmeier Eberhard Grube Chad E. Grueter Christophe Guignabert Rajiv Gulati Kristine J. Guleserian Paul A. Gurbel Michelle Gurvitz Tomasz Guzik Mariann Gyongyosi H Richard Ha Gilbert Habib Francois Haddad C. Hadigan Albert Hagege Rebecca T. Hahn Roger Hajjar Saptarsi Haldar Jennifer L. Hall Florencia Halperin Jonathan L. Halperin Scott D. Halpern Naomi Hamburg Allen Hamdan John W. Hammon Göran K. Hansson Joshua Hare Robert Harrington D. Harrison Ahmed Hasan Babar Hasan Gerd Hasenfuss Paul Hassoun Stephan Haulon Edward Havranek Laura L. Hayman Mary Fran Hazinski Jeff S. Healey David Hehir Tarek Helmy Anna Hemnes Jeroen M. Hendriks Charles Henrikson Timothy Henry Adrian Hernandez Teri Hernandez David M. Herrington Howard C. Herrmann Richard Heuser Richard R. Heuser James Thomas Heywood Kathleen Hickey Robert S. Higgins Charles Hill Joseph A. Hill Gerhard Hindricks Rabea Hinkel Loren F. Hiratzka Alan T. Hirsch Jennifer C. Hirsch Marie-France Hivert Carolyn Ho Vincent B. Ho Judith Hochman Udo Hoffmann Ulrich Hofmann Brian D. Hoit David Holmes Geu-Ru Hong Ting-Ting Hong Michael Hope Lisa Hornberger Jay Horton Steven R. Houser Virginia J. Howard Tzung K. Hsiai Patrick C.H. Hsieh Daphne T. Hsu Priscilla Hsue Dayi Hu Erich Huang Kurt Huber Christopher Hugo-Hamman Scientific Sessions’ faculty — experts in various aspects of cardiovascular health and science — will share their experiences and expertise. Come and hear what they have to say. 24 Marc Humbert Scott L. Hummel Yong Huo Karen Huss Elaine Hylek I Gianluca Iacobellis John Ikonomidis Frank F. Ing Thomas Inge Jodie Ingles Ignacio Inglessis Silvio Inzucchi Matthew Ito Joachim Ix J Alice K. Jacobs Jeffrey Jacobs Jill Jacobs Marshall L. Jacobs Terry A. Jacobson Iris Jaffe Farouc Jaffer Mukesh Jain Jose Jalife Cindy James Stefan K. James Karin A. JandeleitDahm Ewa A. Jankowska Jan Janousek James Januzzi Christine Jellis Kathy Jenkins Catriona S. Jennings Mark Jeong Michael Jerosch-Herold Mariell Jessup Wendy Jessup Zhang Jian LI Jianping Zheng Gen Jin Hani Jneid Hanjoong Jo Roby Joehanes Anitha John Heather Johnson Jason Johnson Maryl Johnson American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org Rachel Johnson Peter Jones Steven R. Jones Steven P. Jones Susan Joseph Karen E. Joynt Daniel Judge Markus Juonala K Stefan Kaab Annemarie Kaan Ashish Kabra Susan Kahn Ajay K. Kakkar Kamyar KalantarZadeh Jonathan Kaltman Timothy Kamp Peter M. Kang Joshua Kanter David P. Kao Samir Kapadia Navin Kapur Saibal Kar Keyvan KarimiGalougahi Juan C. Kaski Robert Kass John J. Kastelein Sekar Kathiresan Peter Katzmarzyk John Kaufman Rae-Ellen Kavey Clifford J. Kavinsky Dhruv S. Kazi Aaron S. Kelly Daniel P. Kelly Walter Kernan Kiarri Kershaw Bryan Kestenbaum Christopher Kevil Paul Khairy Faisal Khan Amit Khera Eugene G. Kholmovski Alok Khorana Bob Kiaii Gregory Kicska Michael Kiernan Ahmet Kilic Kee Sik Kim Soo Hyun Kim Carey D. Kimmelstiel TEST YOUR CARDIAC SKILLS SIMULATION ZONE IN THE BODY INTERACT The virtual patient in this innovative, life-like cloud platform comes with dynamic monitoring, dialoguing, test orders, scans, drugs, intervention options and performance debriefing. Medical case scenarios presented on the immersive 3D touchscreen are problem-based in areas such as stroke, atrial fibrillation and heart failure. MECHANICAL CIRCULATORY SUPPORT This hands-on opportunity allows you to model critical scenarios and observe hemodynamic consequences. A total artificial heart mock circulatory loop paired with axial and centrifugal continuous flow devices will test scenarios such as inadequate preload/afterload conditions, right heart failure and device obstruction. Visit the Simulation Zone in booth 101 during scheduled sessions or drop by at your convenience to experience the devices on your own. The schedule of sessions will be available for viewing in the Mobile Meeting Guide App (available for download in mid-October) and in the Final Program available on-site. ADVANCE PROGRAM AND FACULTY George King Bronwyn Anne Kingwell Scott Kinlay Raj Kishore Eddy Kizana Jesper Kjaergaard Allan Klein Dawn Kleindorfer Monica E. Kleinman Jeffrey Kline N. Jennifer Klinedinst Paul Knaapen Joshua Knowles Walter Koch Robb D. Kociol Wolfgang Koenig Kwang Koh Lisa Kohr Michel Komajda Issei Komuro Marvin Konstam Maria Kontaridis Michael C. Kontos Anatol Kontush Jelena Kornej Mikhail Kosiborod Andrew Krahn Christopher M. Kramer Litsa Kranias William Kraus Catherine Krawczeski Thomas Krieg Penny Kris-Etherton Karl-Heinz Kuck Bernhard Kuhn Alexander Kulik Hemant Kulkarni Raman Krishna Kumar Uday Kumar Sawan Kumar Jha Sonia Kunstmann Bonnie Ky L Mark La Meir Ronald V. Lacro Neal Lakdawala Carolyn S. Lam Pier Lambiase Rachel J. Lampert Patrizio Lancellotti Michael Landzberg John Lane Irene M. Lang 26 Jason Lang Emmanuel Lansac Michael Lauer Carl Lavie Nathan Lawson Jennifer Lawton Pietro Enea Lazzerini Anson Lee Christopher S. Lee Dongwon Lee Jason Lee Maarten J. Leening Barbara Leeper Nicholas Leeper David J. Lefer Leslie Leinwand Jonathon Leipsic Lawrence Leiter Martin Leon Jonathan Leor Annarosa Leri Glenn N. Levine Robert A. Levine Emily B. Levitan Daniel Levy Jerrold H. Levy Jack C. Lewin Gregory Lewis Lisa Lewis Tene Lewis Jin Li Ren-Ke Li Renhao Li Mingyu Liang Ronglih Liao Peter Libby Alice H. Lichtenstein Joao Lima Joy Lincoln JoAnn Lindenfeld Arne Lindgren Merry Lindsey Charlotte Ling Mark Link Gregory Lip Steven E. Lipshultz Kasia J. Lipska M. Teresa T. Lira Harold Litt Stephen Little Sheldon Litwin Sarah Livesay Donald M. LloydJones Barry London Gary Lopaschuk Francisco LopezJimenez Jose Luis LopezSendon Joseph Loscalzo Steven Lubitz Thomas F. Lüscher James M. Luther M Daqing Ma Calum A. MacRae Michael Madani Thomas Maddox Meenakshi Madhur Ahmed Magdy Elizabeth Magnuson Felix Mahfoud Ehtisham Mahmud Lynn Mahony Marjorie S. Maillet Francesco Maisano Mark W. Majesky Maulik Majmudar Ziad Mallat Simon Maltais Alice Maltret Rekha Mankad Sunil V. Mankad Douglas L. Mann Warren Manning Ganesh Manoharan JoAnn E. Manson Eduardo Marban Francis Marchlinski James Marcin Gregory M. Marcus Ariane Marelli Kenneth Margulies Daniel B. Mark Michael Markl Bradley Maron James F. Martin Kathleen A. Martin Alejandro Martinez Tami Martino Tom Marwick Justin C. Mason Frederick A. Masoudi Verghese Mathew Scot Matkovich Dan Matlock Hiromi Matsubara Chisa Matsumoto David L. Mattson Nicola Maurea Mathew Maurer Laura Mauri Kreton Mavromatis Manuel Mayr Janine M. Mazabob Mervyn Maze Mjaye L. Mazwi Pamela J. McCabe Patrick M. McCarthy Kathleen McCauley Michael V. McConnell Brian McCrindle Peter A. McCullough Mary McDermott Alicia A. McDonough Tom McElderry Carmel McEniery Anthony W. McGuire Colleen K. McIlvennan Timothy A. McKinsey Vallerie V. McLaughlin Julie R. McMullen John McMurray Elizabeth McNally Robert L. McNamara Jessica L. Mega Mandeep R. Mehra Roxana Mehran Puja K. Mehta James B. Meigs Liu Meilin Jolyane Meloche Matthew Menard Venugopal Menon George Mensah Laura Mercer Rosa Raina Merchant Luc Mertens Thierry Mesana Markus Meyer Deborah Meyers Joseph Miano Evangelos D. Michelakis Hector Michelena Lisa Mielniczuk Jennifer H. Mieres Ricardo Migliore Anastasia S. Mihailidou David J. Milan Carmelo Milano Dianna Milewicz Federico Milla John Miller Leslie W. Miller Luann Minich Margo Minissian Gary S. Mintz Mahek Mirza Paras Kumar Mishra Seema Mital Yoshihide Mitani William E. Mitch Gary Mitchell DImitrios Mitsouras Christina Y. Miyake Sara Mobasseri Peter J. Mohler Carlos A. Molina Jeffery D. Molkentin Paul Monagle David Montani Jean Moody-Williams Philip Moons Shirley M. Moore Samia Mora Victor Morell Carlos A. Morillo Nicholas Morrell Shaine Morris Debra K. Moser Ivan Moskowitz Javid Moslehi Richard Moss Patrick Most Mahasin Mujahid Elizabeth Murphy Michael Murphy Jenna M. Murray Niren Murthy Vemuri S. Murthy Venkatesh L. Murthy Kiran Musunuru Jonathon Myers N Gerald Naccarelli Sathyamangla V. Naga Prasad Eike Nagel Sherif Nagueh Matthias Nahrendorf Atsushi Nakano Satoshi Nakatani Vijay Nambi Navin C. Nanda Nawazish Naqvi Sanjiv Narayan American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org Jagat Narula Andrea Natale Meena Nathan Stanley Nattel Saman Nazarian Sean-Xavier Neath Mona Nemer Petr Neuzil Jane W. Newburger L. Kristin Newby Kim Newlin Christopher Newton-Cheh Tien Ng Elsie Nguyen Graham Nichol Mark Nicolls Jo Ann Nieves Petros Nihoyannopoulos Ravi Nistala Thilo Noack Jerzy Roch Nofer Raul G. Nogueira Anju Nohria Borge Nordestgaard Samar Noureddine O Christopher J. O’Donnell Patrick T. O’Gara Christopher O‘Connor Anush Oganesian Takeshi Ogo Young S. Oh Vahagn Ohanyan Jeffrey W. Olin Guillermo Oliver Iacopo Olivotto Brian Olshansky Eric N. Olson Anders G. Olsson Suzanne Oparil Ali Oto Oztekin Oto Kinya Otsu Catherine M. Otto Jingsong Ou Bruce Ovbiagele Neville Owen Anjali Tiku Owens Christopher D. Owens ADVANCE PROGRAM AND FACULTY P Douglas L. Packer Milton Packer Francis D. Pagani Patrick J. Pagano Richard Page Robert L. Page Stephen Page Elfriede Pahl Igor F. Palacios Latha Palaniappan Miguel Pampaloni Reena L. Pande Peter S. Pang David Paniagua Bishnu Panigrahi Angelo A. D. Paola Anand Parekh Nisha Parikh Seong-Mi Park Seung Woo Park Sara Pasquali Robert H. Pass Mitesh Patel J. Herbert Patterson Kristen Patton Nina Paynter William F. Peacock Thomas A. Pearson Carlos Pedra Patricia A. Pellikka Michael Pencina Daniel Penny Carl J. Pepine Naveen Pereira Néstor G. Pérez Emerson C. Perin Frederic Perros Karlheinz Peter Nicholas Peters Eric D. Peterson Randall Peterson Anna S. Petronio Gosta B. Pettersson Michael Petty Duc Thinh Pham Melanie Philipp Mariann Piano Gregory Piazza Philippe Pibarot Michael H. Picard Jonathan Piccini Luc Pierard Anna Pilbrow Ileana L. Pina Peipei Ping Duane Pinto Fausto Pinto Bertram Pitt Geoffrey S. Pitt Kian-Keong Poh Paul Poirier Venkateshwar Polsani Piotr Ponikowski Zoran Popovic Athena Poppas Wendy Post Janet Powell Tiffany M. Powell-Wiley Bunny J. Pozehl Sumanth Prabhu Aruna Pradhan Siddharth Prakash Abhiram Prasad Randy Prather Charlotte A. Pratt Bernard Prendergast Richard Price Juan Carlos Prieto Silvia G. Priori Vincent Probst Steve Provencher Janet Prvu Bettger Bruce Psaty William Pu Yuh Fen Pung Kuberan Pushparajah John Puskas Houry Puzantian Q Zhen Qian Candida C. Quarta Arshed A. Quyyumi R Marlene Rabinovitch Daniel J. Rader Wolfgang A.K. Radtke Gilbert Raff Mohammed Yusoff Rahal Vivek Rajagopal Sanjay Rajagopalan Basel Ramlawi Janani Rangaswami Gadiparthi Rao Sunil V. Rao More than 1,500 faculty will present during Scientific Sessions 2015. Antonio Rapacciuolo Ravi Rasalingam Helge H. Rasmussen Anis Rassi Suman Rathbun Vinod Ravi Patricia Reant Michael J. Reardon Rita Redberg Gautham P. Reddy Vivek Reddy Nancy Redeker Margaret M. Redfield Andrew Redington Judith Regensteiner Vera Regitz Zagrosek Muredach P. Reilly Benjamin Reinking Jared P. Reis Carol Remme Kathryn M. Rexrode Harmony R. Reynolds Matthew Reynolds Henrique B. Ribeiro Michael W. Rich Paul M. Ridker Barbara Riegel Niels Riksen Sarah Rinehart Clint Robbins Jeffrey Robbins Susan Roberts Jennifer G. Robinson Petra Rocic Howard Rockman Stanley Rockson Dan Roden Jo Ellen Rodgers Carlos J. Rodriguez Veronique L. Roger Anand Rohatgi Alvaro Rojas-Pena Mary J. Roman Jonathan Rome Matthew Rondina Emilio Ros Jonathan Rosand Raphael Rosenhek Stefan Rosenkranz David Rosenthal Heather Ross Robert Ross Greg Roth Beverly A. Rothermel Gary S. Roubin Faye Routledge R. Daniel Rudic Marc Ruel Zaverio Ruggeri Marta Ruiz-Ortega Paolo Rusconi Mark W. Russell John Ryan Frank J. Rybicki Jack Rychik Kerry-Anne Rye S Marc Sabatine Craig Sable Ritu Sachdeva Frank Sacks Sakthivel Sadayappan Junichi Sadoshima Susmita Sahoo Yoshikatsu Saiki Hajime Sakuma Sameh Salama Susan Saleeb Anne Sales Nilesh Samani Alejandra San Martin Eduardo Sanchez Pedro Sanchez Prashanthan Sanders Darshak Sanghavi Monika Sanghavi Raul Santos Carlos G. SantosGallego Mark Sarnak Jonathan Satin Toru Satoh Naveed Sattar Jeff Saucerman William Henry Sauer Jacqueline Saw Douglas Sawyer Michael Sayre Mauricio Scanavacca Philip Schauer Melvin M. Scheinman Ralph Schermuly Marielle ScherrerCrosbie Mark A. Scheurer David Schidlow Ernesto Schiffrin Ann Marie Schmidt Boris Schmidt Michael Schneider Jeanette Schulz-Menger P. Christian Schulze Andrew Schwartz Peter Schwartz Steven Schwartz Benjamin Scirica Jane D. Scott Christine Seidman Alexander Seifalian Christian Seiler Frank Sellke Marc Semigran Christopher Semsarian Sue Sendelbach Yoshihiro Seo Patrick W. Serruys Rose B. Shaffer Dipan J. Shah Maully Shah Mitesh Shah Sanjiv Shah Svati H. Shah Tina Shah Catherine Shanahan Oz Shapira Sanjay Sharma Leslee Shaw Robin Mark Shaw Christina M. Shay Soren P. Sheikh scientificsessions.org | American Heart Association Scientific Sessions 2015 Preview 27 ADVANCE PROGRAM AND FACULTY Lara Shekerdemian Win Kuang K. Shen Matthew W. Sherwood Chi Young Shim Hiroaki Shimokawa Andrew Y. Shin Mehdi Shishehbor Kalyanam Shivkumar Ralph Shohet Rosa Sicari Horst Sievert Jennifer Avari Silva Candice Silversides Craig Simmons Kit N. Simpson Daniel Singer Pranava Sinha Karin Sipido Hamayak Sisakyan Olivier Sitbon Steven Small Nicholas Smedira Jonathan D. Smith Peter Smith Sidney C. Smith Steven Smith Kim Smolderen Harold Snieder Piotr Sobieszczyk John Solaro Scott D. Solomon Prem Soman Virend K. Somers lars Sondergaard Erica Sood John Spertus Thomas L. Spray Bonnie Spring Christopher Spurney Deepak Srivastava Sanjay Srivastava Marie-Pierre St-Onge Julie St-Pierre Randall Starling Sandy Staveski Charles Steenbergen Jr. Philippe Gabriel Steg Michael Steigner Paul Stein Benjamin A. Steinberg Julia Steinberger Steven Steinhubl Elaine E. Steinke Kurt R. Stenmark Elizabeth Stephenson David Stepp 28 Lynne Warner Stevenson William G. Stevenson Duncan J. Stewart Garrick Stewart Arthur Stillman Nathan Stitziel Neil J. Stone Karen Stout Sharon Straus Mary Straw Erik Stroes Anna Strömberg Wilber Su Anne E. Sumner Zhongjie Sun Kjetil Sunde Mark A. Sussman Robert Sutton Erik Suuronen Karl Swedberg Nancy Sweitzer Keith Swetz Filip K. Swirski David M. Systrom T Tamas Szili-Torok Ira Tabas Sarah Tabbutt Heinrich Taegtmeyer Kei Takahashi Masafumi Takahashi Masaaki Takeuchi Alan R. Tall Jacqueline TamisHolland Ru San Tan Hidekazu Tanaka Wilson Tang Victor F. Tapson Jil C. Tardiff Herman A. Taylor W. Robert Taylor Ruth Taylor-Piliae Patrick J. Tchou John R. Teerlink Martin Teraa Cesare Terracciano Paul Terry Jeffrey Testani Jeff Teuteberg Paaladinesh Thavendiranathan Thenappan Thenappan Judith Therrien Ravi Thiagarajan Dierk Thomas Gregory Thomas Randal Thomas Sara Thorne Vinod H. Thourani Thomas Thum Kristian Thygesen Rong Tian Jens M. Titze Stefano Toldo Eser Tolunay Gordon F. Tomaselli Bonnie Tong Rhian Touyz Jeffrey A. Towbin Dwight A. Towler Raymond Townsend Mark I. Travin Diane Treat-Jacobson Jennifer Tremmel Jennifer Trilk Le Trinh Emily J. Tsai Connie Tsao Omaç Tufekcioglu Mintu Turakhia James R. Turk Sony Tuteja-Stevens James S. Tweddell Marysia Tweet Anne Tybjaerg-Hansen U James Udelson Elaine Urbina Masuko Ushio-Fukai V Miguel Valderrabano Anne Marie Valente Glen S. Van Arsdell Jop H. van Berlo Frans Van de Werf Pim Van Der Harst Peter Van Der Meer Jolanda Van Der Velden Jennifer Van Eyk Isabelle C. Van Gelder Linda Van Horn Eva van Rooij Toon van Veen David R. Van Wagoner Mani A. Vannan Orly Vardeny Stephanie Vaughn Ashley Vavra Rajesh Vedanthan Hugo Moreno Velazquez Ercole Vellone Luigi Venetucci Lakshmi Venkitachalam Hector O. Ventura Arie Verkerk Atul Verma Subodh Verma Hillary J. Vernon Kasey C. Vickers Ronald Victor Mladen Vidovich Julie Vincent Salim S. Virani Pierre Voisine Thomas M. Vondriska Marc Vos Pascal Vranckx W Reza Wakili Ron Waksman David Wald Jennifer Walker Michelle Wallace Lars Wallentin Edward Walsh Kenneth Walsh Dirk Walter Da-Zhi Wang Hong Wang Paul J. Wang Thomas Wang Tracy Wang Xuejun Wang Yibin Wang Steven Warach Stephanie Ware Jason H. Wasfy Nozomi Watanabe Hugh C. Watkins Karol E. Watson Connie Weaver Christian Weber Gregory Webster Xander Wehrens Guy Weigold William Weintraub Richard Weisel Jeffrey Weitz Hein Wellens Cheryl Wellington Robert C. Welsh Nanette Wenger Gil Wernovsky Jennifer Wessel Paul K. Whelton Nathan J. White John Whitlock Debra Wiegand Anthony Wierzbicki Anthony S. Wierzbicki Georg Wieselthaler David J. Wilber Joellen Wilbur Christopher S. Wilcox Peter Willeit David O. Williams Gordon Williams Kim A. Williams Mathew R. Williams Monte Willis Melissa Wilson Peter Wilson Joseph Witztum Myles Wolf Jessica G. Woo Joseph Woo David A. Wood David Wood Kathryn Wood Pamela Woodard Bradford B. Worrall Clinton B. Wright Jackson T. Wright Janet S. Wright R. Scott Wright Connie Wu Joseph C. Wu Mei-Hwan Wu Sean Wu X Chen Xiaoyuan Qingbo Xu American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org Y Jay Yadav Steven J. Yakubov Clyde W. Yancy Phillip C. Yang Xiao-Feng Yang Demetris Yannopoulos Zemin Yao Bernice Yates Dileep R. Yavagal Yerem Yeghiazarians Edward Yeh Robert Yeh Liya Yin Gerald Yonga Shi-Joon Yoo Michael Yost Deborah R. Young Martin E. Young Cheuk-Man Yu Paul B. Yu Salim Yusuf Katherine E. Yutzey Z Justin P. Zachariah Evan Zahn Osama O. Zaidat Alexander Zambon Jose Luis Zamorano Steven Zangwill Faiez Zannad David C. Zawieja Andreas Zeiher Mary Zellinger Parounak A. Zelveian Julie J. Zerwic Uwe Zeymer Jianyi Zhang Dong Zhao Li-Ru Zhao Xiao Zhou Cheng Zhu Khaled Ziada Michael R. Zile Peter Zimetbaum William Zoghbi Ming Zou Coert Zuurbier AMP UP your Scientific Sessions experience More can’t-miss opportunities • EP Central • HealthTech Competition • Simulation Zone • Meet the Trialist • Complimentary coffee breaks • Free lunch in Product Theaters • AHA HeartQuarters • Engage with more than 200 exhibitors • Hands-on CPR training • AHA Bistro • FREE professional photos taken • Complimentary Wi-Fi lounge and charging stations SCIENCE & TECHNOLOGY HALL HOURS | Nov. 8: 11 a.m. – 4 p.m. | Nov. 9: 10 a.m. – 4 p.m. | Nov. 10: 10 a.m. – 2:30 p.m. SCIENCE & TECHNOLOGY HALL/UNOFFICIAL SATELLITE EVENTS TECHNOLOGY VISIT THESE 2015 EXHIBITORS A–C A Fashion Hayvin, Inc. Accusplit Make a Difference Programs, Actelion Pharmaceuticals US Inc ADInstruments, Inc Advanced Cooling Therapy, Inc. Advocate Children’s Hospital AHA Hands-Only CPR Training AHA HeartQuarters AliveCor, Inc. AltaThera Pharmaceuticals Amarin Pharma plc Ambry Genetics American Board of Clinical Lipidology American College of Cardiology Amgen Arbor Pharmaceuticals Arrhythmia Alliance AstraZeneca Pharmaceuticals AtCor Medical Inc. Banyan Bayer Healthcare Blueprint Genetics BMS/Pfizer Boehringer Ingelheim Pharma, Inc. Cardiology Today and Healio.com By Slack Inc. CellAegis Devices Inc. Channing Bete Co. Children’s Medical Center of Dallas 30 China Heart Federation (CHF) ContextMedia Health Coravin Cyfuse Biomedical KK Cytokinetics D–F Daiichi Sankyo, Inc. Dassault Systèmes SIMULIA DMT-USA, Inc. Duke Clinical Research Institute Edwards Lifesciences Egg Nutrition Center Eko Devices Elsevier Emerging Science & Technologies emka Technologies Inc. Fukuda Denshi G–I Genzyme a Sanofi Company Gilead Sciences, Inc. Hawaiian Moon HeartSine Technologies HeartWare Hitachi Aloka Medical Hugo Sachs Elektronik/Harvard Apparatus Ideal Protien of America, Inc. IEM Infinite Therapeutics Intermountain Heart Institute Inventive Medical Ltd (Heart Works) InvivoSciences Inc. IonOptix Itamar Medical J–L The JAMA Network Janssen Pharmaceuticals, Inc. The Japanese Circulation Society John Welsh Cardiovascular Diagnostic Lab The Joint Commission Karger Publishers Laerdal Medical M–O Mayo Clinic Mayo Clinic Cardiovascular Self-Study Tutorials Med Learning Group American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org SCIENCE & TECHNOLOGY HALL/UNOFFICIAL SATELLITE EVENTS Medicure Medley Farmaceutica Medtronic Merck Millar, Inc. MNG Laboratories Mortara Instrument, Inc. Multi Channel Systems National Death Index National Kidney Foundation National Lipid Association NEJM Group Nihon Kohden America NorthEast Monitoring, Inc. Northwestern Medicine Novartis Pharmaceuticals Corp. Oxford University Press P–S Panasonic Healthcare Corp. Panasonic Wellness Perosphere Inc. Pfizer Inc. Physio-Control Pikeville Medical Center, Inc. Portola Pharmaceuticals, Inc. Pozen Preventive Cardiovascular Nurses Assn. PCNA PromoCell GmbH QGenda, Inc. Relypsa Inc. Sanofi Sanofi / Regeneron Scarf King Seahorse Bioscience Sony Biotechnology Stocosil Stryker EXHIBITOR HIGHLIGHTS Thank you to the following exhibitors that have supported the Scientific Sessions Conference Preview. T–Z Taylor and Francis theheart.org/Medscape Cardiology Thoratec Corp. TIMI Study Group TSE Systems, Inc. UF Health Shands Hospital UltraScope VisualSonics W.A. Baum Co., Inc. Wake Forest Innovations Wiley Wolters Kluwer WorldPoint ZOLL Medical Corp. ZS Pharma The Science & Technology Hall will be open from 11 a.m. to 4 p.m., Sunday, Nov. 8; 10 a.m. to 4 p.m., Monday, Nov. 9; and 10 a.m. to 2:30 p.m., Tuesday, Nov. 10. While every effort is made to ensure the accuracy of data within this publication, the publisher cannot be held responsible for errors or omissions. Data current as of Aug. 25, 2015. scientificsessions.org | American Heart Association Scientific Sessions 2015 Preview 31 SCIENCE & TECHNOLOGY HALL/UNOFFICIAL SATELLITE EVENTS CARDIOVASCULAR EXPERT THEATERS DATE/TIME S pend your lunch time at the Cardiovascular Expert Theaters, located in the Science & Technology Hall. Sessions given by industry supporters will introduce you to the latest cardiovascular products on the market. Complimentary lunch provided. BOOTH SUPPORTER 11:15 a.m.-Noon Booth 1601 Amgen 11:15 a.m.-Noon Booth 163 Amarin Pharma 11:15 a.m.-Noon Booth 1559 Sanofi-Regeneron 12:30–1:15 p.m. Booth 1601 Janssen Pharmaceuticals, Inc. 12:30–1:15 p.m. Booth 163 Pfizer 12:30–1:15 p.m. Booth 1559 Amgen Noon-12:45 p.m. Booth 1601 Sanofi-Regeneron Noon-12:45 p.m. Booth 163 Merck Noon-12:45 p.m. Booth 1559 Amgen 1:15-2 p.m. Booth 1601 Boehringer Ingelheim Pharmaceuticals, Inc. and Medtronic 1:15-2 p.m. Booth 163 Amgen 1:15-2 p.m. Booth 1559 Novartis Pharmaceuticals Corporation Noon-12:45 p.m. Booth 1601 Amgen Noon-12:45 p.m. Booth 163 Boehringer Ingelheim Pharmaceuticals, Inc. Noon-12:45 p.m. Booth 1559 Daiichi Sankyo, Inc. 1:15-2 p.m. Booth 1601 Daiichi Sankyo, Inc. 1:15-2 p.m. Booth 163 Relypsa, Inc. 1:15-2 p.m. Booth 1559 AstraZeneca SUNDAY, NOV. 8 MONDAY, NOV. 9 TUESDAY, NOV. 10 Two sets of Cardiovascular Expert Theaters will be offered each day on Sunday, Nov. 8; Monday, Nov. 9 and Tuesday, Nov. 10. 32 American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org Grow Your Professional Network at Scientific Sessions 2015 You may be early in your career, a seasoned physician or a researcher. No matter the career or specialty, the connections you make during Sessions will extend your knowledge and help you enhance your professional mission and ultimately patient outcomes. Find the right networking environment for you: • Meet the Trialists: Connect with the researchers involved in some of the biggest trials of 2015. • EP Central: A new place for electrophysiologists and others interested in EP to exchange information and relax. • Early Career: Gather career-building resources and engage with senior investigators in a full day of sessions, networking events and a lounge. • Science & Technology Hall: Visit with 200+ exhibiting companies showcasing the latest cardiovascular technology and resources. • Poster Hall: Have one-on-one conversations with poster presenters and top researchers. • Members-Only Activities: Enjoy AHA Scientific Council meetings, committee meetings, council dinners, luncheons, lounges and more! • Science Subcommittee Collaboration Station: Learn how you can be a part of the 35 essential AHA Science Subcommittees. scientificsessions.org #AHA15 Photos ©2014 AHA/Todd Buchanan Join the industry’s global elite and register today for a chance to grow your professional connections. SCIENCE & TECHNOLOGY HALL/UNOFFICIAL SATELLITE EVENTS LEARNING MONDAY, NOV. 9 EVENING Secondary Prevention of Atherothrombotic Events: Current Insights on Advancing Science Provided by Vindico Medical Education Supported by Merck & Co. UNOFFICIAL SATELLITE EVENTS Registration link: www.vindicocme.com/110815 SATURDAY, NOV. 7 SUNDAY, NOV. 8 Sponsored by Voxmedia AFTERNOON EVENING Registration link: www.symposiareg.com/21513 Acute Coronary Syndrome in Younger Women: Unique Risks, Etiologies, Treatments and Opportunities Cardio-Oncology — A New Era, An Evolving Discipline TUESDAY, NOV. 10 An Expert Forum: Hot Topics in Stable Ischemic Heart Disease Management Supported by Gilead Sciences Medical Affairs Sponsored and supported by the Mayo Clinic MORNING Sponsored and supported by the Mayo Clinic Optimizing LDL Targeted Cardiovascular Risk Reduction EVENING Sponsored by the University of Massachusetts Management of Hypertrophic Cardiomyopathy for the Clinical Cardiologist Supported by Sanofi and Regeneron Sponsored by Washington University School Registration link: www.reg-LDL.com Medical School Pharmaceuticals of Medicine Continuing Medical Education AF Spotlight: Using NOACs Safely Supported by Washington University and Barnes-Jewish Heart & Vascular Center Sponsored by the Postgraduate Institute for Registration link: BarnesJewish.org/orlando2015 Medicine and Medtelligence A 3-D View Statin Therapy — Only Part of a Comprehensive Approach to Dyslipidemia Management Sponsored by Med Learning Group Supported by an educational grant from Eli Lilly Challenges in Cholesterol Management What Your Patients Might Not Be Telling You: A Town Hall Symposium Sponsored by Global Academy for Medical Supported by Boehringer Ingelheim Pharmaceuticals, Inc. and Daiichi Sankyo, Inc. Education Supported by Pfizer Registration link: events.medtelligence.net/ha2015. html Industry supported symposia 34 University non-profit symposia American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org While every effort is made to ensure the accuracy of data within this publication, the publisher cannot be held responsible for errors or omissions. Data current as of Aug. 12, 2015. EXPECT BIG Science BIG Clinical Content BIG Technology BIG Networking See why Scientific Sessions is the global conference of choice for cardiovascular professionals. THINGS 23 17,000 RESEARCHERS • CLINICIANS • NURSES +1.5 million a Global Perspective FROM SPECIAL & NAMED lectures countries 45% international 55% domestic who attends: EMTs • Technicians • Pharma • Students • Early Career the BEST science + 5,000 presentations INCLUDING 1,500 FACULTY INVITED 4,000 ABSTRACTS LATEST-BREAKING Clinical Trials ARRHYTHMIA RESEARCH SUMMIT Cardiovascular Nursing Clinical Symposium ReSS are now part of SCIENTIFIC SESSIONS 30 programming tracks INCLUDES 3 NEW TRACKS: CARDIOVASCULAR PROFESSIONALS virtual attendees 200+ exhibitors technology + resources Hands-on activities in new SIMULATION ZONE Become a PROFESSIONAL MEMBER and save up to Clinical Trialists Health Tech on registration Workplace Health Register by September 9 to take advantage of early registration and book housing. Exhibits: November 8–10 | Sessions: November 7–11 $400 CONTINUING EDUCATION credits available LEARN MORE scientificsessions.org/registrationandhousing DISCOVER ORLANDO FUN IN ORLANDO TAKE OFF As one of the most popular destination cities in the world, Orlando is accustomed to handling a crowd — the city saw more than 62 million visitors last year alone. Orlando International Airport is only a 25-minute drive from the Orange County Convention Center and offers thousands of non-stop flights. You should book your flight early for the best times and fares. • AHA Travel Service: 800-999-9717, Monday-Friday, 8 a.m.-6 p.m. CST • American Airlines: 800-221-2255 • Your own travel agent 36 Visit Orlando W hen it comes to destination cities, Orlando, Florida, ranks among the biggest. Home to more than a dozen theme parks, the magic of the city doesn’t end there. More than 100 other attractions help secure Orlando’s spot on nearly every vacation Top 10 list, as well as validate its distinction as the most visited destination in the country. Once the meeting is adjourned, world superb restaurants, championship golf courses, world-class spas, captivating museum exhibitions and more than 1,200 retail shops await you. Whether you’re looking for a quick getaway after meetings or an all-day excursion for your accompanying family or friends, Orlando offers something for every schedule and interest. Swim with dolphins, play 18 holes on a world-class golf course, dine in some of the most inspired restaurants in the world or, yes, conquer the roller coasters. Orlando has the perfect adventure for you. Screamin’ Gator Zip Line at Gatorland BLUE MAN GROUP AT UNIVERSAL ORLANDO bluemanorlando.com This world-renowned show is a curiously captivating mash-up of totally unique live music, unexpected humor and lots of paint. The group’s inventive comedy and audience interaction with multimedia theatrics combine to create a blissful party atmosphere. CAPONE’S DINNER & SHOW alcapones.com Become a member of a Chicago crime family. At this “family gathering,” you’ll be informed by Al Capone himself about a “rat” in the organization and asked to help “take care of it.” The entire staff and audience participate in the fun, which includes an allyou-can-eat dinner buffet. CLEARWATER MARINE AQUARIUM seewinter.com The world’s best-known marine life rescue center is home to Winter, the world’s most famous dolphin and star of the major motion picture Dolphin Tale. You’ll also see Atlantic bottlenose dolphins, sea turtles, river otters, sting rays and sharks at the aquarium. It’s worth the trip. KISSIMMEE SWAMP TOURS kissimmeeswamptours.com Explore 35,000 acres of untouched wild beauty; no development, no houses. This American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org DISCOVER ORLANDO guided airboat tour will take you through pristine swamps and marshes in the Orlando and Kissimmee area to see the “old Florida.” ripleys.com/orlando An unbelievable variety of artifacts and displays in 16 unique galleries that pay tribute to the odd and the strange, inspired by Robert Ripley himself. Marvel at the collection of weird and unusual relics during this self-guided, self-paced tour. The unusual building itself is worth the trip. SCREAMIN’ GATOR ZIP LINE AT GATORLAND gatorland.com SEAWORLD DISCOVERY COVE discoverycove.com Get up close like never before in the Dolphin Lagoon, Freshwater Oasis or The Grand Reef where you’ll experience aquatic wildlife and choose from personal interactions. Swim with dolphins, snorkel with exotic fish or come face-to-face with a playful otter. Just relax and explore. HOLLYWOOD DRIVE-IN GOLF hollywooddriveingolf.com Based on vintage horror flicks and “little green men” science fiction films, guests putt through elaborate movie-style scenes when they choose from two 18-hole minigolf courses. This state-of-the art attraction is completely family friendly. Kennedy Space Center Visitor Complex Clip in and zip off on an exciting outdoor adventure with the all-new Screamin’ Gator Zip Line at Gatorland. Your journey will take you along 1,200 feet of high-flying, heartpounding adventure from some of the finest zip line towers in the world. T he list of hot spots for familyfriendly fun in Orlando is endless. Plan ahead and make visiting these parks and attractions the perfect way for your family or friends to spend a day. Visit Orlando RIPLEY’S BELIEVE IT OR NOT! ORLANDO ODDITORIUM PLAN AHEAD FOR FAMILY FUN IFLY ORLANDO INDOOR SKYDIVING orlando.iflyworld.com Experience true free-fall conditions, just like skydiving, without having to jump out of an airplane. It’s safe for kids (as young as 3), challenging for adults and realistic for skydivers. They provide all the gear and personal instruction. MARINELAND DOLPHIN ADVENTURE marineland.net Experience dolphins in a whole new way with one of Marineland’s programs that will bring you face to face with these ocean ambassadors. You can swim with dolphins, paint with them or simply touch and feed them. Advance reservations are recommended. WILD FLORIDA WILDLIFE PARK orlandotaste.com wildfloridairboats.com Experience the area’s culture and meaning through food during a three-hour tour throughout Orlando and Central Florida. There are several tours to choose from, each taking patrons to four or five handpicked restaurants or eateries for bite-sized samplings of selected dishes that represent both the chef and the city well. Zebras, watusi, deer, tropical birds, sloths, lemurs, monster alligators and many more wild animals make this park their home. With more than 150 native and exotic animals, there is something for everyone to see. KENNEDY SPACE CENTER VISITOR COMPLEX kennedyspacecenter.com THE GREAT ESCAPE ROOM thegreatescaperoom.com Put your survival skills to the test as you analyze clever clues to find secret passageways and hidden compartments during a 60-minute frantic search for freedom. Will you be able to find a way out? Wild Florida Wildlife Park TANTALIZING TASTES & TOURS See where the U.S. space program began, and find out where it’s going. The space center is the only place where you can walk among the actual rockets of the Mercury, Apollo and Gemini missions. You also can meet a veteran astronaut from NASA’s famous astronaut corps at Astronaut Encounter, occurring daily. scientificsessions.org | American Heart Association Scientific Sessions 2015 Preview 37 Don’t Be Fooled a nd Miss the Savings ! Save a t Least $200 Throug h 11/11 ! Experience Magic at Your Fingertips with Sessions OnDemand™ Premium • Spellbinding Videos of Scientific Sessions 2015 Presentations • Captivating Cardiovascular Science as Never Seen Before • Downloadable PDFs of the Presenter Slides and MP3 Audio • Anywhere, Anytime Online Access and Optional USB Drive – Only $50 Plus Shipping Purchase at sessionsondemand.org Download the Mobile Meeting Guide 9:15 AM Dashboard Mobile app available at scientificsessions.org/mobile My Schedule Educational Sessions Faculty Abstracts Unofficial Programs Science & Tech Hall Maps Get It At Sessions Sessions Daily News AHA Newsroom Science News Updates Social Networks AHA EVENTS 2015 Use the above QR code to download the meeting guide app now or search and download the app from the Google play or App Store by searching “AHA Events”! ©2015, American Heart Association 8/15DS9611 AMERICAN HEART ASSOCIATION SCIENTIFIC SESSIONS 2015 DO-NOW CHECKLIST NOW IS THE TIME TO MAKE YOUR PLANS TO ATTEND SCIENTIFIC SESSIONS 2015 IN ORLANDO. The American Heart Association’s Scientific Sessions has the best science and is the leading cardiovascular conference for basic, translational, clinical and population science in the United States. Make sure you don’t miss a thing. ❏ REGISTER TODAY ❏ RENEW YOUR MEMBERSHIP ❏ MAKE A MUST-SEE EXHIBITOR LIST New this year: One registration fee! When you register for Scientific Sessions 2015, you receive access to all Scientific Sessions programming, including the Resuscitation Science Symposium and the Cardiovascular Nursing Clinical Symposium. Plus, if you register online, you’ll save $20. Visit scientificsessions.org > Registration & Housing. Make sure your AHA/ASA Professional Membership is up to date. Join or become a member by visiting my.americanheart. org/professional/Membership/Membership_ UCM_316891_SubHomePage.jsp. You’ll find the latest in technology, services and products all inside the Science & Technology Hall. Make note of the areas dedicated to the tools and resources for your business and practice. ❏ PLAN YOUR SCHEDULE ❏ DOWNLOAD OUR MOBILE APPS Customize your learning by using areas of interest designed to help you navigate the meeting. There are 30 areas divided into five categories — Basic, Clinical, Population, Special Focus and Frontiers in Science — allowing you to focus your education in your specialty or expand your knowledge in other areas. Visit scientificsessions.org > Programming > 30 Programming Tracks. Want your Scientific Sessions neatly packaged to go? Get the Mobile Meeting Guide app. It will help you navigate while on site and provide instant access to event information. Watch for the link to be available in October by searching “AHA Events” in Google play or the App Store. Also now available in more sessions: Conference Notes. Visit presentations and take notes using Conference Notes — an online, iPad- and laptop-friendly tool. More information will be available soon at scientificsessions.org. ❏ SET UP HOUSING Whether your taste runs more Hilton or Hard Rock, you’ll want to get your hotel reservations locked down. To help in your selection, AHA has sorted available hotels by price, location and amenities. Visit scientificsessions.org > Registration & Housing > Hotel List and Map. 40 American Heart Association Scientific Sessions 2015 Preview | scientificsessions.org Scan this code to register REGISTER ONLINE AT: WWW.SYMPOSIAREG.COM/21513 *Compliments of Apple watch & iPad drawing* *See rules and regulations at www.symposiareg.com/21513 AGENDA 6:30 PM Registration and Dinner 7:00 PM Introduction Co-Chairs: Valentin Fuster, MD, PhD and Karol Watson, MD, PhD 7:10 PM Clinical Evaluation of Women with Suspected Ischemic Heart Disease: Addressing the Challenges Karol Watson, MD, PhD 7:30 PM Are We Tailoring Antianginal Medications to Our SIHD Patients, or Using Our Favorite Drugs? Benjamin Scirica, MD, MPH 7:50 PM Case Presentation C. Noel Bairey Merz, MD 8:05 PM Revascularizing the Non-diabetic SIHD Patient with Multivessel Disease: Clarifying the Decision of PCI vs CABG Valentin Fuster, MD, PhD 8:25 PM Case Presentation Deepak Bhatt, MD, MPH 8:40 PM Question-and-Answer 9:00 PM Conclusion of Program AN EXPERT FORUM: CO-CHAIRS Valentin Fuster, MD, PhD Professor of Medicine Icahn School of Medicine at Mount Sinai New York, New York Karol Watson, MD, PhD Professor of Medicine David Geffen School of Medicine University of California, Los Angeles Los Angeles, California FACULTY C. Noel Bairey Merz, MD Professor of Medicine Cedars-Sinai Medical Center, Heart Institute Los Angeles, California Monday, November 9, 2015 Registration and Dinner: 6:30 PM – 7:00 PM Symposium: 7:00 PM – 9:00 PM Rosen Centre Hotel Grand Ballroom C Deepak Bhatt, MD, MPH Professor of Medicine Harvard Medical School Boston, Massachusetts Benjamin Scirica, MD, MPH Associate Professor of Medicine Harvard Medical School Boston, Massachusetts 9840 International Drive Orlando, Florida This event is not part of the official Scientific Sessions 2015 as planned by the AHA Committee on Scientific Sessions Programming. This activity is supported by an independent educational grant from Gilead Sciences Medical Affairs. This program is sponsored by What more is there to learn about platelet activation and aggregation? Find out at Booth 701 Copyright © 2015 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc. All rights reserved. CARD-1141095-0005 08/15
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