PATRICK SOON-SHIONG INNOVATION AWARDS
Transcription
PATRICK SOON-SHIONG INNOVATION AWARDS
19_45_pss_innovation_awards_2013.qxp 11/21/2013 5:57 PM Page 19 November 25, 2013 • Advertising Supplement to the Los Angeles Business Journal LOS ANGELES BUSINESS JOURNAL PRESENTS PATRICK SOON-SHIONG INNOVATION AWARDS Presenting Sponsors: Platinum Sponsors: Gold Sponsors: BlackLine Systems OEwaves, Inc. OneWest Bank USC Viterbi School of Engineering This special advertising supplement did not involve the reporting or editing staff of the Los Angeles Business Journal. 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:31 PM Page 20 20 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 Letter from the publisher HE Los Angeles Business Journal is honored to once again present the annual Patrick Soon-Shiong Innovation Awards for 2013. The greater Los Angeles region has long been a thriving home to many of the most exciting and groundbreaking companies in the world – and today that is the case more than ever. We recognize that our region’s tremendous stew of ingenuity, innovation and creativity is what in many ways sparks the economic competitiveness of the region and brings a distinct and unique edge to our local economy. It is with great admiration and respect for great ideas that we at the Los Angeles Business Journal are particularly proud to present this year’s Awards alongside Patrick SoonShiong, whose very name has become synonymous with groundbreaking innovation. This special award program was created with the vision to celebrate the organizations that continue to stretch boundaries. Dr. Soon-Shiong himself has more than led by example – he’s a brilliant entrepreneur who has repeatedly illustrated how the innovative spirit can drive economic value. Moreover, he shares our desire to acknowledge and encourage innovation and has once again made the commitment to underwrite this prestigious award program. Thanks to Dr. Soon-Shiong and the other terrific minds that played a role in helping us select our honorees. This year, the awards were handed out at a ceremony on November 14th at the Four Seasons Hotel Los Angeles in Beverly Hills. Congratulations to this year’s five extraordinary honorees and ten exceptional finalists – each of whom continues to inspire us and provide invaluable contributions to keeping Los Angeles at the forefront of innovation. T Matt Toledo Publisher & CEO Business Journal publisher Matt Toledo and Dr. Patrick Soon-Shiong Dr. Patrick Soon-Shiong, Innovator A regular atop the Los Angeles Business Journal’s list of Wealthiest Angelenos, and a past recipient of the LABJ’s “Business Person of the Year” (thanks to his significant business successes and philanthropic contributions), Dr. Patrick Soon-Shiong is no stranger to the pages of our publication. Dr. Patrick Soon-Shiong knows as well as anyone that innovation, coupled with passion and hard work, is the engine for success in business – not to mention a catalyst for life enhancing, or even lifesaving activity. His groundbreaking concepts for curing diabetes led to the first nanotechnology-based breast cancer drug, Abraxane, which is credited with saving thousands of lives. He’s since made time to research personalized drug therapies based on people’s gene sets, one of the hottest trends in research. Now, for the third year, his love of innovation has prompted him to once again join the Business Journal in handing out Patrick Soon-Shiong Innovation Awards to deserving organizations that may in fact remind Soon-Shiong a little bit of his own early stages as a passionate entrepreneur and innovator. We created this very special awards program to showcase Los Angeles as a place of innovation for businesses – and innovation in business nearly always leads to growth. Here’s a closer look at the inspiration and namesake of our innovation award, Dr. Patrick Soon-Shiong: Dr. Soon-Shiong was raised in apartheid South Africa by his Chinese immigrant parents; his father fled China during World War II and practiced traditional Asian medicine. Soon-Shiong was a stellar student in medical school, becoming a doctor at age 23, but had to accept an internship at a major Johannesburg hospital at half the pay earned by his white counterparts. He completed his surgical training at UCLA and was a member of the medical school faculty by the age of 31, in 1983. Three years later, he performed the first pancreas transplant on the West Coast. He built his fortune by taking American Pharmaceutical Partners public in 2001 and selling it in 2008. He spun off another company, Abraxis, in 2007, then sold it in 2010. He regularly donates portions of his billions to philanthropic causes, including a $136-million donation to St. John’s Health Center in Santa Monica and a $100-million guarantee to underwrite efforts to reopen Martin Luther King Jr. Hospital. He now has his hands in supercomputing, augmented intelligence and other industries through his NantWorks company, which he founded in 2011. The year before, he helped launch the Healthcare Transformation Institute and currently heads the CSS Institute for Advanced Health, which focuses on human genotyping. He hopes to create a national healthcare information network and has taken over the National LambdaRail, the high-speed connector that links academic medical researchers nationwide. meet the innovators! Watch an interview about innovation with Matt Toledo, Dr. Patrick Soon-Shiong and all of our Awards Finalists. Also, watch to learn more about each Winner and their company’s innovations. Three easy steps: 1. Download the FREE iD Browser on your tablet or phone. 2. Open iD Browser and snap a picture of any page showing the iD Browser logo. 3. A screen will appear once recognized. Tap the link on the screen and hold over the image again. You’ll see the images appear over the page. Tap the image that appears and enjoy the video. idbrowser.com 19_45_pss_innovation_awards_2013.qxp NOVEMBER 25, 2013 11/21/2013 4:08 PM Page 21 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL 21 Congratulations to BlackLine Systems Therese Tucker Campus Explorer Jerry Slavonia GumGum, Inc. Ophir Tanz OEwaves, Inc. Lute Maleki, Ph.D SAFCell, Inc. Calum Chisholm on receiving the 2013 Patrick Soon-Shiong Innovation Award 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:32 PM Page 22 22 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 Winner blackline systems Woodland Hills CCOUNT reconciliation is an underappreciated, yet critical, control to help ensure an organization’s financial integrity. Weaknesses and inefficiencies in the reconciliation process often lead to mistakes on the balance sheet and overall inaccuracies in the financial close. An efficient, accurate and timely financial close cycle can create a foundation for evaluating business performance, supporting organizational decisions and satisfying external reporting requirements. Automation of the account reconciliation process is a critical step on the road to achieving ‘balance sheet integrity’ – and ultimately producing accurate financial statements. BlackLine Systems was the first to develop and offer a commercially available Balance Sheet Account Reconciliation solution to automate these critical accounting processes. More than 90 percent of companies still do account reconciliations manually. Hard to believe when you consider all the regional offices, subsidiaries and disparate geographic locations of most large corporations. A Therese Tucker of Blackline Systems BlackLine Systems’ Account Reconciliation software automates and controls manual accounting processes that users often perform primarily using Excel spreadsheets. For years much of the work within accounting departments has been rote and manual-labor intensive. As a result, there’s been a tidal wave of outsourcing designed to cut costs. But by outsourcing accounting jobs to less skilled labor offshore, companies lose the valuable analytical skills and strategic value that accountants can bring. By developing software to, for the first time, automate traditionally manual financial close processes, BlackLine Systems CEO and Founder Therese Tucker has helped improve the lives of accountants around the world. From a high level, BlackLine’s innovation comes from bringing new technologies to support existing (and mission-critical) accounting practices by offering software that, for the first time, automates the entire account reconciliation and financial close processes for large organizations. From a more technical standpoint, BlackLine’s innovation comes from two areas: 1) The BlackLine Financial Close Suite is delivered over the Internet in a secure Software-as-a-Service (SaaS) environment – one of the first apps ever to handle sensitive corporate financial data safely and securely in a SaaS model; and 2) Via a set of rules to process mass data to focus accounting departments with a priority-driven focus. As an example, BlackLine provides client-configurable templates and tools that are based on good accounting practices but that also enable companies to quickly and easily adapt the tools to their internal practices to maximize the value they get from the BlackLine application. Because BlackLine is deployed in a SaaS environment, it eliminates the need for capital expenditure approval, saving customers a great deal of time and money upfront. In addition, unlike other SaaS companies that outsource their operations, BlackLine actually finds it more effective to manage operations in-house, allowing it to have complete control over its systems and further ensure the security of client data. BlackLine touts “no-risk” implementations because the occurrence of technical issues is so small/negligible. In many cases, client IT departments don’t even have to be involved. And, BlackLine is the only SAP Partner in its space, with software certified for integration with SAP ERP Financial and Business Suite solutions. 19_45_pss_innovation_awards_2013.qxp 11/21/2013 4:36 PM Page 23 NOVEMBER 25, 2013 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL 23 THE PRIVATE BANKING AND INVESTMENT GROUP AT MERRILL LYNCH SALUTES THE DR. PATRICK SOON–SHIONG INNOVATIVE AWARDS. RECOGNIZING INNOVATION AND ENTREPRENEURSHIP. COMMITMENT, DEDICATION AND A BETTER TOMORROW – QUALITIES THAT ENRICH ALL OF US Merrill Lynch Private Wealth Advisors are committed to helping those individuals and organizations who are invaluable assets to the community. The Gray Group Eric Gray Managing Director–Wealth Management Private Wealth Advisor 310.407.3979 Private Banking and Investment Group 2049 Century Park East Los Angeles, CA 90067 The Bull Symbol, Merrill Lynch Wealth Management and The Power of the Right Advisor are registered trademarks or trademarks of Bank of America Corporation. Merrill Lynch Wealth Management makes available products and services offered by Merrill Lynch, Pierce, Fenner & Smith Incorporated, a registered broker-dealer and member SIPC, and other subsidiaries of Bank of America Corporation. The Private Banking and Investment Group is a division of MLPF&S that offers a broad array of personalized wealth management products and services. © 2013 Bank of America Corporation. All rights reserved. AD-10-13-1225 AR34P3I5-09-12 444621PM-11/2013 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:32 PM Page 24 24 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 Winner campus explorer Santa Monica to the National Association of College Admission Counseling (NACAC) only 30% of high schools have a college counselor — a ratio of 467 students for every one counselor. Offline and online search and planning tools have been hard-to-use and lack a personalized experience and either cater to a narrow subset of students or profile a narrow subset of schools. Campus Explorer and its founder and CEO Jerry Slavonia are shifting this paradigm by having developed the premier college search engine and planning website available today. Campus Explorer is addressing the limitations in the college search and planning tools available to students previously by providing a superior network for students to connect with the college admissions counselors that are interested in recruiting them. The site has become a destination for the 45 million people each year that research information about higher education. It is a service that can be accessed anywhere via computer, tablet, or mobile phone and caters to all types of students as well as parents, counselors and CCORDING A Jerry Slavonia of Campus Explorer other advisors. Much more than a basic search tool, the system offers expert advice and tips to help guide users throughout the entire process of planning for and paying for college. Campus Explorer maintains a comprehensive database of over 8,500 campuses and online schools ranging from 4-year private and public college, to community college and vocational schools. Detailed profiles include photos, videos and information on college admissions, expenses, academics and more. Intuitive and user-friendly tools help students discover and compare schools, calculate admissions chances and showcase themselves to colleges. The system even offers counselors and other advisors tools to track and participate in a student’s college search and planning process, upgrading and update the very nature in which students discover and connect with schools. Partner schools have been able to increase their pool of high intent inquiries, as Campus Explorer students are both qualified and “raising their hand,” thus generating a higher inquiry to enrollment yields than alternative recruitment channels. Each prospective student can build a richly detailed profile for Universities to review. The profiles include data points such as geographic information, GPA and standardized test scores, financial status, gender and ethnicity, academic and extra-curricular activities, and more. Schools have recognized Campus Explorer’s innovative approach to online student recruitment. Currently, over 2,000 schools are utilizing Campus Explorer to connect with approximately 70,000 student inquiries each month, making Campus Explorer one of the leading recruitment solutions available. CampusExplorer.com has fast become a place to begin that process, with everything students need for a college search, all at one site. Whether it’s a two- or four-year school, a career college or an online program, Campus Explorer provides data on everything from tuition cost to average temperature. The site even contains a personalized search function that allows users to set a wish list and explore from there. Innovative in a number of ways, Campus Explorer is accurate, easy to use, the most comprehensive directory devoted to higher education available on the web – and it’s free! 19_45_pss_innovation_awards_2013.qxp NOVEMBER 25, 2013 11/21/2013 12:02 PM Page 25 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL 25 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:32 PM Page 26 26 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 Winner gumgum inc. Santa Monica UMGUM is a new kind of digital advertising platform for publishers and brands, built on the fundamental belief that to be effective, ads need to be seen and they must make a lasting impression in the minds of the consumers. GumGum develops brand advertising that works specifically on desktops, tablets and smart phones, by creating innovative technology and media designed to drive higher viewability, relevance and brand engagement. Known best for in-image advertising, GumGum was founded in 2007, and its first product was released in early 2008. Since then, the GumGum platform has grown to reach 214 million unique visitors worldwide as they visit hundreds of publisher partner websites. GumGum has diversified its products to include other display, mobile and video solutions to help brands tell their stories and publishers unlock new sources of revenue. Innovation is in GumGum’s DNA. At its core, the company is a technology-based organization founded by G Ophir Tanz of GumGum Inc. a Carnegie Mellon graduate and developed by some of the most talented big data engineers and image scientists in the world. The company holds multiple patents related to image recognition and the ability to target relevant ads according to an understanding of the meaning of photos across GumGum’s platform. GumGum created and revolutionized the in-image advertising category and has invested heavily in educating the market and further establishing itself as the leading provider of this emerging advertising channel. GumGum’s patented image recognition technology allows the company to identify the meaning of photos for the purpose of displaying the most relevant ads possible. The result is an enhanced classification for relevant targeting on a keyword or category basis. GumGum performs this through image analysis, including both meta data that accompanies photos and the ability to determine the meaning of images at a deep technical level based on the semantic analysis of a page and complex computer vision algorithms. GumGum founder, entrepreneur Ophir Tanz, holds innovation as a core value and has always held a passion for technology, design and imagery. The company’s engineering team is using some of the newest big data tools available, such as Kafka, Storm, Hbase and Hadoop; its image scientists recently filed patents for a new LURID Image Classification System that identifies images containing nudity; and earlier this year GumGum created the first image take-over unit. Tanz has been an innovator from a young age. While completing his secondary education at Buckley School in Sherman Oaks, he began reading about technology and attending computer programming classes at UCLA. He went on to attend Carnegie Mellon University, where he graduated simultaneously with an M.S. and B.S. degree in information systems in 2004. He returned to Los Angeles in 2007 to develop a pre-smart phone mobile photo sharing application called MoJungle, which he later sold to UK-based mobile carrier Shozu. As the CEO and founder of GumGum, Tanz has already made his mark as an innovator by inventing the very concept of in-image advertising, which may well revolutionize the advertising industry by making ads more relevant and engaging for consumers. 19_45_pss_innovation_awards_2013.qxp NOVEMBER 25, 2013 11/21/2013 11:47 AM Page 27 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL 27 Proud sponsor of the Congratulations to each winner and finalist for ideas that are as outstanding in execution as they are imaginative in spirit. Fish & Associates is a premium, full-service intellectual property law firm, helping innovators, entrepreneurs, scientists and business leaders meet and exceed their IP goals. Innovators ourselves, the Fish & Associates team is making dreams come true one ground-breaking idea after another. 2603 Main Street, Suite 1000 · Irvine, CA 92614-4271 Phone: (949) 943-8300 · Fax: (949) 943-8358 E m a i l : i n f o @ f i s h i p l a w. c o m w w w. f i s h i p l a w. c o m 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:33 PM Page 28 28 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 Winner oewaves inc. Pasadena EWAVES Inc. transforms novel microwave photonic technologies, from concept to products in the marketplace, to enable new and advanced capabilities in communications, radar, and test and measurement systems. The innovative technology introduced by OEwaves allows reduction of size, weight, and power of these systems and enables their deployment on small platforms. Advanced radar systems, for example, suitable only for use on large aircraft, can be re-architected based on OEwaves’ technologies to fit on hand-launched Unmanned Aerial Vehicles (UAVs). These emerging platforms have already found multitudes of applications in service of commercial and military functions, ranging from search and rescue, to homeland security, and battlefield force protection. OEwaves’ technologies significantly enhance the usefulness of UAVs by making it possible to add the type of advanced sensors that are otherwise unavailable to them. Beyond this, OEwaves’ technologies allow data link architectures and future advanced WiFi with order of magnitude improvement in capacity. O Lute Maleki, Ph.D., of OEwaves Inc. OEwaves’ innovation story started with the invention of a unique oscillator known as the Opto-Electronic Oscillator (OEO) at the Jet Propulsion Laboratory. Oscillators generate the carrier waves in systems that receive and transmit information. The performance of the oscillator determines the data handling capacity of the system and information processing capability. The same considerations apply to high performance test and measurement systems and high performance radar. For nearly 75 years, high performance quartz oscillators have been the workhorses for these applications. As the appetite for consumption of information has grown, quartz and other electronic technologies are becoming unable to deliver the needed performance. Soon after its invention, the OEO was recognized as a transformative technology that could address the emerging needs. OEwaves was formed to further develop and commercialize this innovation. OEOs use light from a laser, together with various other optical components, that result in the generation of a microwave reference signal. OEwaves developed and introduced an innovation to miniaturize the OEO from the size of a PC tower to the size of a postage stamp. This innovation is the development of a tiny object known as optical whisper- ing gallery mode resonator. The name is derived from an observation long ago that certain domes, such as the dome of the St. Peter’s cathedral, sustain energy so that whispers spoken on the far side of the of the cathedral go around the dome and may be heard as whispers on the other side. Similarly, tiny dome-like structures made with transparent crystals, sustain light energy introduced to them by having light travel around so many turns that it is equivalent to a path defined by many kilometers of optical fiber. In the past few years OEwaves has introduced other innovations based on its core technologies and has developed novel components (filters, downconverters, etc.) with unprecedented performance. In short, OEwaves has transformed scientific and technological innovations to make possible capabilities that represent major value to national problems and to the market place. And while OEwaves’ innovations have already shown important impact in defense applications and in the commercial fiber optic sensing market, this success is only representative of new applications yet to come. 19_45_pss_innovation_awards_2013.qxp NOVEMBER 25, 2013 11/21/2013 11:46 AM Page 29 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL 29 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:33 PM Page 30 30 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 Winner safcell inc. Pasadena AFCell, Inc. develops scalable solid acid fuel cell (SAFC) stacks for applications requiring tens of watts to tens of kilowatts. Operating at mid-range temperatures around 250°C, SAFCell’s stacks tolerate fuel impurities that pose obstacles to other fuel cell technologies. This allows SAFCell stacks to run more easily on commercially available gas fuels (e.g., propane and butane) or liquid fuels (e.g., methanol, diesel and biooils), greatly reducing the overall fuel cell system complexity and cost. SAFCell is partnering with targeted system integrators to enter first portable, and then stationary power markets. SAFCell’s core technology is the use of a solid acid electrolyte (CsH2PO4), a solid-state proton conducting material intermediate between normal salts and normal acids, pioneered at the California Institute of Technology (Caltech). High fuel impurity tolerances allow SAFCs to run on commercially available fuels, such as propane and diesel, with minimal system complexity. As such, SAFCs offer significant durability and cost advantages over these s Calum Chisholm of SAFCell Inc. lower-temperature fuel cell technologies when operating on commercially available fuels. In combination to the use of commercial fuels, SAFC’s stacks are made of inexpensive metal and polymer components that both reduce overall stack costs and result in a very rugged stack design. Other fuel cell technologies that tolerate such fuel impurities operate much higher temperatures, driving up the cost and reducing durability. As such, only SAFCs offer the combination of commercial fuel use, high durability, and low stack costs when compared to both lower and higher temperature fuel cell technologies. Compared to standard generators, SAFCs deliver longer lifetimes with less maintenance. SAFCell, Inc. was founded in November of 2009 by Dr. Calum R.I. Chisholm and five other dedicated cofounders, to develop and commercialize SAFCs. However, the story of this technology goes back ten years earlier to the Materials Science Department at Caltech, where as a graduate student Dr. Chisholm and fellow graduate student, Dr. Dane Boysen, made the first solid acid fuel cell, generating a whopping 15 micro-Watts of power. Since then, the technology has been scaled to the over 1.5 kW, a million fold increase in power output. Drs. Chisholm and Boysen investigated the fundamental properties of a class of materials known as superprotonic solid acids, named such for their ability to transform into highly conductive solid-state proton conductors under specific temperature/pressure conditions. During their scientific investigations, and in collaboration with other scientists, it became clear that the materials could operate stably under fuel cell conditions. Since then, the SAFCell team has automated cell fabrication and streamlined stack fabrication, resulting in a very stable stack platform producing tens to thousands of kilowatts. These robust and rugged pre-commercial stacks have helped to convince multiple system integrators to build full SAFC systems running off of methanol, propane, natural gas, and diesel fuels. Ongoing efforts will produce the first commercial SAFC power units in 2014 for portable and mobile power applications. Future development efforts at the cell and stack level will increase stack lifetimes and decrease stack costs, allowing SAFC power units to enter into small stationary markets, like remote, back-up, and residential power. 19_45_pss_innovation_awards_2013.qxp NOVEMBER 25, 2013 11/21/2013 11:46 AM Page 31 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL 31 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:33 PM Page 32 32 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 finalists meet the innovators armagen technologies inc. Calabasas has the promise for developing new potent drugs for treatment of serious brain diseases such as Alzheimer’s and stroke, as well as devastating childhood genetic disorders that affect the brain. However, biotech drugs cannot be developed for brain diseases, because these pharmaceuticals are “large molecule” drugs that do not penetrate the brain’s protective wall, called the blood-brain barrier (BBB). ArmaGen Technologies, a company founded in 2004 by William M. Pardridge, M.D., a professor of medicine at UCLA, has developed the first platform technology that enables the re-engineering of biotech drugs as BBBpenetrating agents. This is possible thanks to ArmaGen’s molecular Trojan horse technology – a genetically engineered monoclonal antibody that traverses the BBB via transport on endogenous transport systems. ArmaGen then takes the gene that produces the Trojan horse, and fuses it to another gene that makes the biotech drug. The process creates a new fusion gene that produces a new chimeric protein where half of the new fusion protein is the brain-active drug and half of the fusion protein is the Trojan horse. The Trojan horse portion of the fusion protein ferries the biotech drug across the BBB and into the brain. Without the Trojan horse element, the biotech drug would not be able to penetrate the BBB and would not be able to enter clinical trials. The goal is for this Trojan horse technology to be rapidly applied by leading pharmaceutical companies to unleash their broad biologic portfolios to the field of neuroscience and alter the outcome for patients facing life-threatening brain diseases. B IOTECHNOLOGY William Pardridge, M.D., of Armagen Technologies Inc. edgecast networks Santa Monica HE internet is inherently inefficient, as it is made up of hundreds of different networks that were built by local telecommunication providers. As a result, internet traffic is slowed down when passing through these different networks at exchange points. Enter EdgeCast Networks, a company that since its inception in 2006 has stayed true to its mission to “making the web faster and safer” for internet users all over the world. Founded by serial web entrepreneurs, EdgeCast now serves over 5,000 clients and carries over 5% of the global internet traffic on its content delivery network (CDN). The world’s busiest websites, such as Twitter, Hulu, and Yahoo, all rely on EdgeCast’s infrastructure to deliver their content in a fast and secure way to end-users. With global internet usage expected to continue to increase exponentially, inefficiencies can easily become a significant barrier to global economic growth. EdgeCast’s server network allows websites to bypass congestions and deliver their content fast and without loading times to users worldwide. EdgeCast has developed a unique approach to building out its network that sets it apart from competitors. Instead of placing thousands of small servers at many locations, EdgeCast decided to concentrate its server and computing power at key internet exchange points. The company also made a commitment to only using the highest quality equipment for its servers. The result: more throughput, less maintenance, and higher uptime for its equipment that makes EdgeCast’s network more reliable and faster for its clients. T Alex Kazerani of EdgeCast Networks 19_45_pss_innovation_awards_2013.qxp 11/21/2013 11:45 AM Page 33 NOVEMBER 25, 2013 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL 33 PAID ADVERTISEMENT 19_45_pss_innovation_awards_2013.qxp 11/21/2013 2:22 PM Page 35 T:10.875" S:9.875" Enjoy our exclusive Onboard Lounge.* Unwind in the onboard Shower Spa.** And stay entertained with up to 1500 channels of inflight entertainment in all classes. Once aboard the new Emirates A380, non-stop comforts are just part of the experience. Fly Emirates non-stop from LAX to Dubai and beyond, starting December 2nd. emirates.com/us “Airline of the Year” 2013 Skytrax World Airline Awards *Product shown is available in First Class and Business Class. **First Class only. T:15 S:14" Make friends in high places 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:34 PM Page 34 34 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 finalists fuhu inc. El Segundo UHU is the creator of nabi, the first full-featured Android tablet made just for kids. With nabi, Fuhu created a new category in the children’s consumer products and services market that has ignited the trend of children’s Android tablets. While being the first, nabi tablet is also still the #1 selling Android tablet made for children. It is built with the most comprehensive parental controls, a “Time Control” that speaks to kids while helping them monitor their device usage, and the “Wings Learning System” that tailors itself to a child’s proficiency personalized to each child’s proficiency across required common core fundamentals to pass from one grade to the next, it individualizes learning through continuous adaptations throughout the learning path. The system is rigorous and robust with over 3,000 lessons and 50,000 questions aligned with Common Core State Standards. Nabi also contains the exclusive “nabi Coins and Treasure Box” that helps teach children to make the right choices through identifying tasks, setting and managing priorities, and being responsible for them. nabi tablets are award winning and have been reviewed by experts as the leading choice for high-quality tablets made just for kids. Even the device headphones are an innovation in themselves. Each nabi tablet comes equipped with the world’s first dual-mode headphones with SafeSound Technology — professionally tuned and powered by the same advanced circuitry as the more expensive high-end headphones in the market, while limiting the volume without compromising sound quality at 80dB to protect young developing ears from ruining their hearing at an early age. F Jim Mitchell of Fuhu Inc. golden road brewing co. Los Angeles OLDEN Road Brewing Co. is an innovator in the world of beer. The company is the first craft brewery in Southern California to offer its house made beers in a can. While most canned beers are typically maligned as “your dad’s crummy lager,” Golden Road Brewing makes hoppy ales with layers of flavor, and has chosen to can its beer for reasons including preservation of quality, portability, recyclability, and innovation of design. Golden Road’s President Meg Gill explains that the two main enemies of beer are light and air. Light creates an unwanted “skunky” flavor and penetrates through bottles, no matter the color. However, light cannot penetrate aluminum, thus there is never a concern for light strike with cans. Another major quality factor is oxidation. Dissolved oxygen levels tend to be greater in bottles because of that head space from the cap to the liquid in the bottle. Oxygen leaking into the beer, over time, erodes the hoppy, clean, and bright layers desired in Southern Californian beers. Golden Road’s mission is to provide fresh, clean, hoppy beers for the LA palate, so cans became their choice. Another factor behind using innovative packaging is Golden Road’s commitment to sustainability. Cans are infinitely recyclable, while bottles break down after a few uses. Further, 40% more beer can fit in each truck, with over 15 trucks leaving Golden Road’s warehouse per week. From poolside at Beverly Hills Hotel to Trader Joe’s, Ralph’s, Whole Foods, and Costco, Golden Road is now found in over 4000 locations in the greater LA area. G Meg Gill of Golden Road Brewing Co. 19_45_pss_innovation_awards_2013.qxp 11/21/2013 5:29 PM Page 36 36 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL PATRICK SOON-SHIONG INNOVATION AWARDS 2013 finalists l-nutra inc. Culver City -Nutra was organized as a spin-off from USC for the purpose of developing novel, highly efficacious proprietary diets, dietary supplements, medical foods and medicines to optimize longevity and manage acute and chronic disease. These products have been developed based on 20 years of research by Professor Valter Longo, Ph.D., the Edna Jones Chair of Biogerontology and Director of the USC Longevity Institute, and his research team focused on the potent effects of fasting and other extreme diets on cellular physiology and organismal function. L-Nutra’s short-term goal is to develop and commercialize Fasting Mimicking/Enhancing Diets (“FMEDs”) to reduce the rate of cellular aging, protect patients against the side effects of chemotherapy, and slow or reverse age-related diseases including diabetes, cancer and Alzheimer Disease. L-Nutra’s first product, Chemolieve, now being tested at four major University Hospitals, is a Fasting Mimicking and Enhancing Diet that was developed to identify a combination of ingredients to protect normal cells and organs from chemotherapy while making the chemotherapy more effective and the therapy easier for patients. The idea was not to identify another drug that delays the progression of some tumors, but to identify an intervention that can work for the great majority of tumors and that has the potential to cure patients, particularly those with metastatic tumors that have been reduced but not eliminated by conventional treatments. Chemolieve has a remarkable effect on turning a standard chemotherapy that normally only delays cancer progression into a therapy that cures 40-60% of mice from a variety of cancers. L Fabrizio Schirano of L-Nutra Inc. NOVEMBER 25, 2013 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:35 PM Page 37 NOVEMBER 25, 2013 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL 37 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 lyxia corp. Los Angeles L YXIA Corporation is an early stage company focusing on biofuel technology and other relevant environmental strategies. Its mission lies in the commercialization of a disruptive technology from UCLA that enables microalgae to rapidly and directly convert CO2 into ASTM-certified crude oil. While the current sugar-based microalgae biofuel industry is striving against the spread between sugars and fuels, researchers and scientists are exploring an efficient, natural way of directly converting carbon dioxide into fuels via microalgae. One possible candidate to this question in a commercial scale deployment could be Botryococcus Braunii, a green, pyramid shaped planktonic microalga, which lives in fresh water, but can also adapt to a large range of sea salt concentration. Botryococcus Braunii produces hydrocarbons, which have been described as equivalent to the “gas-oil fraction of crude oil.” Like petroleum, these hydrocarbons can be turned into gasoline, kerosene and diesel. Three research groups spent five years on engineering B.braunii to optimize its growth and biofuel yield. Accidently, Lyxia founder Wei Yu and his team found a combinational use of catalysts with special pH treatment could contribute to a dramatic increase of growth rate and oil yield. In addition, this procedure only uses small amounts of catalysts, which avoid the use of expensive corn-based feed or glucose. Lyxia aims to build a scalable plant in Southern California to demonstrate the production capacity using its proprietary formula. Eventually Lyxia could utilize this technology to help supplement or even substitute the use of fossil fuels. Wei Yu of Lyxia Corp. 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:36 PM Page 38 38 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 finalists neurorecovery technologies inc. Los Angeles VER one million people in the United States cannot walk, plus hundreds of thousands have lost control of body temperature, bladder, bowel, and sexual function as a result of spinal cord injury. NeuroRecovery Technologies’’ multi-disciplinary team has developed a technology that will enable the dream of regaining these vital functions back. The technology NeuroRecovery Technologies has developed consists of two new, cutting-edge spinal cord neuromodulator systems. Each is composed of a pulse generator with complimentary electrode, allowing for both implantable and external use in restoring functional capacity to patients suffering with paralysis. Both devices were developed by world-renowned neuro-physiologist and research scientist Dr. V. Reggie Edgerton, along with his team of associates from UCLA, Cal Tech, and The University of Louisville. Current implantable spinal cord neuromodulators on the market are approved for pain control only, while external stimulators are approved for the management of pain, to improve peripheral circulation, and to enhance wound healing. NeuroRecovery Technologies’ neurostimulators will be labeled to facilitate the restoration of movement, and to restore functional control to multiple organ systems. These innovative devices are capable of modulating the spinal cord by delivering multiple electrical frequencies, current and waveforms. The units are rechargeable and will have the ability to integrate with adjunctive equipment, such as physical therapy equipment or a pharmaceutical pump. They also contain wireless communication technologies for transmitting and receiving data. Aside from restoring movement, the overall effectiveness of these neuromodulator systems is estimated to reduce cost of lifetime care for spinal cord injury patients by 40 percent or more. O Nick Terrafranca Jr., DPM of NeuroRecovery Technologies Inc. Congratulations to Therese Tucker and the entire team at Thank you to the Chan Soon-Shiong Family Foundation for supporting the University of California Global Health Institute in its mission to improve the health of the world’s most vulnerable populations. on your nomination for the 2013 Patrick Soon-Shiong Innovation Award Tom and Janet Unterman Haile T. Debas, MD, UCSF UCGHI Director Thomas J. Coates, PhD, UCLA UCGHI Co-director 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:36 PM Page 39 NOVEMBER 25, 2013 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL 39 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 protabit llc Pasadena ROTABIT is a protein engineering firm founded in 2009 with the goal of creating a platform technology that could be used to optimize the properties of enzymes and proteins for use in industrial, agricultural, and therapeutics applications. Proteins can be engineered through the manipulation of their primary sequence to take on desired properties for improved stability, activity, specificity, and shelf-life. Protabit combines the best available computational tools and laboratory techniques to yield specialized proteins. Its technological edge is a world-class, commercial-grade software platform (Triad) built in partnership with Caltech and Monsanto. Triad integrates proven computational approaches to protein design, allowing the user unprecedented flexibility in tailoring the methodology for specific design goals. This flexibility gives the software broad applicability in protein optimization and discovery and will facilitate the integration of future protein engineering breakthroughs. By applying physics-based simulations of protein sequences, Triad can search enormous sequence spaces to rapidly find variants that are very different from the parent protein. This in silico approach eliminates sequences that are unstable or unfolded so that drastically fewer variants must be screened experimentally; this process speeds discovery and saves time and money. One of Protabit’s commercial goals is to apply this technology to rapidly engineer more cost-effective cellulolytic enzymes for converting biomass to fermentable sugars for use in the production of biofuels and other sustainable products. The company is customizing enzymes for optimal activity on different cellulosic feedstocks under a variety of industrial conditions. Customized high-performance enzymes can enable higher throughput, reduce environmental impact, and decrease total processing costs. P Barry Olafson of Protabit LLC 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:37 PM Page 40 40 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 finalists scorebig inc. Los Angeles COREBIG.COM is an innovation that is disrupting the $20 billion live entertainment industry by addressing two of the biggest challenges facing that sector: increasing unsold ticket inventory and the rising cost of live entertainment for consumers. The interactive user-friendly ScoreBig.com site enables consumers to get excellent tickets for live sports, concerts and theater events at guaranteed savings of up to 60 percent. ScoreBig.com customers pick their own price on seats from the floor to the rafters, always pay less than box office price, and never pay any additional fees. ScoreBig.com’s system has successfully developed the only “pick your price” model that effectively moves unsold inventory while addressing the threat of brand erosion inherent with traditional discounting. Traditional discounting is tremendously problematic for ticket sellers because it can damage their hard-earned brand value and alienate season ticket holders. CEO and Co-founder Adam Kanner came up with the idea for ScoreBig.com as a senior NBA marketing executive, when he experienced the problem of unsold inventory and the perils of transparent discounting first hand. When he and Joe Milne formed the company in 2009, they knew that analytics had to be infused into every aspect of the business and that the company needed to innovate a breakthrough technology platform to succeed. One of the company’s first executive hires was a PhD in Mathematics, analytics expert Dr. Alison Burnham. ScoreBig.com’s innovative proprietary technology platform was built from the ground up to understand purchase intent and pricing better than any other source in the marketplace. S Joe Milne of ScoreBig Inc. 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:37 PM Page 41 NOVEMBER 25, 2013 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL 41 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 stamps.com El Segundo is a software and web-based program that allows customers to calculate and print valid U.S. postage for domestic letters, packages and international mail without having to go to the Post Office. Individuals, home offices, small businesses and e-commerce sellers can manage their mailing and shipping operations more efficiently and securely than with postage meters or regular stamps. One of the many innovations Stamps.com has brought to the internet postage category includes a USPS Rate Shopping Engine, which allows e-commerce sellers to find the optimum mail class and shipping rate for specific packages. Based on pre-set requirements that are inputted into the software, the program will include a “Best USPS Rate” identifier that highlights the lowest cost option that meets a customer’s pre-set shipping requirements. Stamps.com also enables users to print Certified Mail postage on plain paper. Certified Mail usually involves handwritten forms using special labels, but the Stamps.com technology allows a customer to input data via computer and print Certified Mail postage on a plain piece of paper, which is then placed into our exclusive Certified Mail window envelopes. After printing the address information, Certified Mail tracking barcode and postage on a plain piece of paper, the paper is folded and placed inside a window envelope. All the printed items will be clearly visible through the window envelope. These are just a few of the many (including 125 U.S. patents) innovations Stanps.com has brought to the internet postage world since it was founded in 1996. S TAMPS.COM Ken McBride of Stamps.com Everybody knows spreadsheets can be full of hidden, costly mistakes. That’s why BlackLine replaces spreadsheet processes for: đƫ+1*0ƫ.!+*%(%0%+*/ đƫ*1(ƫ&+1.*(ƫ!*0.%!/ đƫ(+/!ƫ0/'ƫ)*#!)!*0 đƫ.*/0%+*ƫ)0$%*# đƫ.%*!ƫ*(5/%/ đƫ+*/+(% 0%+*ƫ/5/0!)ƫ0%!ġ+10/ BLACKLINE.COM ('%*!ƫ5/0!)/ƫ3+1( ƫ(%'!ƫ0+ƫ+*#.01(0!ƫ((ƫ+"ƫ0$!ƫĂĀāăƫ 0.%'ƫ++*ġ$%+*#ƫ**+20%+*ƫ3. ƫ%**!./ƫ* ƫ%*(%/0/ċ 2013 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:38 PM Page 42 42 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 Event scene Honored guests and attendees were on hand for the event at the Four Seasons Hotel Los Angeles in Beverly Hills; Dr. Patrick Soon-Shiong and wife Michele B. Chan; master of ceremonies Frank Mottek. 19_45_pss_innovation_awards_2013.qxp 11/21/2013 4:38 PM Page 43 What do health care changes mean for your company? If you wonder how the Affordable Care Act (ACA) may impact your company, Anthem Blue Cross is here with answers. We know you don’t have time to read the entire ACA. That’s why we brought together all the important information you need to know in one helpful website — makinghealthcarereformwork.com. The site is full of tools and resources to help you, including: } } } ACA Decision Support Tool. Use this interactive tutorial to learn the basics of ACA and its impact on you and your business. ACA Financial Calculator. Estimate your costs for offering health benefits to your employees. Podcasts. Boost your understanding of particular topics with these helpful audio programs. Listen on your computer or mobile device. You’ll find answers, and learn more about your options, when you visit makinghealthcarereformwork.com today, or call your Anthem sales representative. Visit makinghealthcarereformwork.com. Request your FREE Anthem Quote now, in less than three minutes! 888-432-2583 Anthem Blue Cross is the trade name of Blue Cross of California. Independent licensee of the Blue Cross Association. ® ANTHEM is a registered trademark of Anthem Insurance Companies, Inc. The Blue Cross name and symbol are registered marks of the Blue Cross Association. 42404CAEENABC 11/13 19_45_pss_innovation_awards_2013.qxp 11/21/2013 3:38 PM Page 44 44 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL NOVEMBER 25, 2013 PATRICK SOON-SHIONG INNOVATION AWARDS 2013 Event scene Winners accept their awards: Left to Right, Therese Tucker of BlackLine Systems, Lute Maleki of OEwaves, Calum Chisholm of SAFCell, Dr. Patrick Soon-Shiong, Ophir Tanz of GumGum and Brian Hartnack, Steven Caldwell and Jerry Slavonia of Campus Explorer 19_45_pss_innovation_awards_2013.qxp 11/21/2013 2:59 PM Page 45 NOVEMBER 25, 2013 AN ADVERTISING SUPPLEMENT TO THE LOS ANGELES BUSINESS JOURNAL 45 We are Proud Supporters Kidsave helps older, overlooked orphans and children in foster care find families. www.kidsave.org of Kidsave Thank you to our 2013 golf sponsors and our volunteers Associates Purchasing Aurora Storage Products Blackstone Consulting Brookfield Office Properties Chicago Title Company Equity Office Frances Moreno & Vaco Greenwald, Pauly, Foster & Miller Guardian Life Insurance Company of America Hathaway Dinwiddie HOK Howard Building Corporation Inner Space Constructors Insperity LBA Realty NCM Demolition & Remediation Olpin Group Pinnacle Communications Pinnacle Contracting Corporation SAA 3ARESs2EGIS'ROUP Steelcase Tangram Interiors Turner Construction Cresa Los Angeles 11726 San Vicente Blvd., Suite 500 Los Angeles, CA 90049 310.207.1700 | www.cresa.com Please join us at the next Kidsave LA MiracleMakers Golf Classic on Monday, September 29, 2014. 46 LOS ANGELES BUSINESS JOURNAL November 25, 2013 Los Angeles Business Journal’s 2014 Book of Lists TOP 10 Reasons to advertise in the Book of Lists: 1 2 Guarantee that every CEO on a list reads your ad. 3 4 Reach hidden influencers. 5 Position yourself adjacent to a list you aren’t on and be a part of the conversation. 6 Advertising in the BOL shows your strength to the Business community. 7 It’s extremely cost effective… an ad is referred to 13.2 times per year.* 8 You can communicate your brand’s staying power and relevancy. 9 Kick off your 2014 ad campaign with year-long visibility. 10 The BOL has an exciting new format and magazine size this year… lists are printed both ALPHA and by Industry. Target Decision Makers by aligning your ad next to strategic lists. If you’re not there… your competitor will be! *Readex Subscriber Study Deadline to reserve ad space: December 2, 2013 For advertising information, please call 323.549.5225 Ad Materials Deadline: December 5, 2013