the Cutting Edge - The Ohio State University
Transcription
the Cutting Edge - The Ohio State University
The Buckeye Periodontal Alumni Newsletter the Cutting Edge JULY 2008 Drs. Irma Iskandar/Weiting Ho, Editors Dr. Lewis Claman, Faculty Advisor Volume 11 Issue 1 building on the past - shaping the present - charting the future EDITOR:Editor: DR. Pooja IRMA Maney, ISKANDAR FACULTY ADVISOR: DR. LEWIS CLAMAN BDH, MPH Faculty Advisor: Lewis Claman, DDS VOLUME 11, ISSUE 1 “Ljodhhus” Angelo Mariotti, DDS, PhD, Chair Names can be funny (think Angelo) and selection of names for children can be tricky. I know that when my wife and I were thinking of names for our children, we wanted to have something that sounded nice and had meaning but we also didn’t want a name that was too strange (think Angelo). There are many names that we run across in the day but none has the same ring as Lewis (pronounced LOO iss). The name Lewis is a derivation of the Norwegian name Ljodhhus, meaning the "sounding house." The "sounding house" was a building that housed the men who took the depth of the seas in the local area. Later the Scandinavian name Ljodhhus was further modified in old Frankish Hludwig and old Germanic Chlodowech to become Lewis with a change of meaning to "famous warrior." In Latin it was transformed into Ludovicus, and in Gaelic to Clovis. Medieval Italians turned it into Aloisius, while the French adopted Louis. In the 1940’s, Lewis was one of the more popular names to select for a child in the United States. In fact, during the ‘40s it was ranked as one of the top 120 names to select for a boy. There have not been many famous people with the first name Lewis. Personally I can think of only two people of renown with that name: Lewis Carroll and Lewis Claman. Lewis Carroll lived over 150 years ago in England and wrote surreal stories while Lewis Claman lives in Continued on page 2 From the Editor Greetings everyone! I hope everyone is having a wonderful and relaxing summer. Despite the warm and balmy weather, the OSU Perio clinic is as busy as ever, and the Division is in full swing as the incoming first years start taking their first classes and are getting adapted to our program. I want to thank my mentor of the Cutting Edge, Dr. Claman, and the immediate past editor, Dr. Ho, for their guidance and help. I also want to recognize our new cub reporter, first year Dr. Kevin Harrison, who will Inside this issue: Dr. Irma Iskandar be helping with the organization and publishing of this newsletter. I hope you enjoy the new issue of the Cutting Edge. We will continue profiling OSU alumni, and in this issue we highlight Dr. S. Timothy Rose and his successful contributions to the field of periodontology. Last, please mark your calendar for many important upcoming events including the American Academy of Periodontology annual meeting in Seattle and Dr. Claman’s retirement party. I hope to see you all there. Chairman’s Note 1 From the Editor 1 Voice of the Director 3 Predoctoral Report 5 Awards & New Diplomates 6 Chairman’s Choice 7 2007 Published Articles 15 Perio Alumni Profile 17 Photos 19 Honor Roll of Giving 29 VOLUME 11, ISSUE 1 Page 2 Ljodhhus - Continued Columbus, Ohio and teaches real students at The Ohio State University College of Dentistry. Lewis Claman has been a “famous warrior” in periodontics since the 1970’s and remains a prominent, passionate, honest, industrious, erudite, compassionate, effusive, frank, conscientious, affable man. Most everyone associated with OSU Periodontics knows of “Lewis” but few know that this will be his last six months of full time employment at OSU. Yes…I know it is surprising because it seems like only yesterday that he started to teach at OSU but every good thing must come to an end sometime. So if Lewis Claman was one of those people who came into your life and changed it for the better, then take some time out of your busy schedule and come to Columbus this December to let him know that you won’t forget him. Because any name, whether it be peculiar (think Angelo) or spectacular can be forgotten unless you remember the man behind that name (think Lewis Claman). IMPORTANT NEWS “Ljodhhus” Retirement Symposium For Dr. Lewis Claman Friday, December 5, 2008 @ The Faculty Club on OSU Campus Save the date! The American Academy of Periodontology Meeting Seattle, Washington September 6-9, 2008 Hope to see you there! 1:00-5:00 pm CE (Prior library) 6:00-11:00 pm Dinner (black-tie optional) The Claman Endowment The “Claman Award” will be a new honor bestowed annually on one dental student who Department faculty believe exemplifies excellence in clinical periodontics. Eligible senior dental students must be excellent students with an interest in periodontics. Special consideration will be given to those individuals who are considering a career in academic dentistry. It is the intent of the Department to provide a grant with additional academic rewards (certificate, journal subscription, etc.) for the winner of the Claman Award. Therefore, please consider making a donation to The Claman Endowment so that we can fund this award and increase the interest in OSU dental students to become periodontists that have an inclination to teach. VOLUME 11, ISSUE 1 Page 3 Voice of the Director Dimitris Tatakis DDS, PhD Dear Alumni and Friends, It is almost a year since the last issue of the Cutting Edge, and the last 12 months, full of the many activities of a graduate program, went by very fast. The interview process for the 2008 incoming class took place last autumn. It is very encouraging, both for the program and the specialty, that we had a record number of applicants this past year. The usual two days of interviews became three, and as a result our faculty, residents and staff were quite busy; without everyone being so generous with their time and effort this interview process would not have been possible. We also enjoyed the benefit of having several alumni Drs. Sam DeAngelo (’06), Scott Lightfoot (’04), Ehsan Rezvan (’05), and Ralph Wilson (’02) - participate in the interviews. My sincere thanks go to all involved. Speaking of interviews and candidate selection, I know that some of you are aware of recent allegations that donations influenced admissions into a highly competitive and well-regarded Advanced Dental Education program in California (http://dailybruin.com/ news/2007/nov/13/). The above allegations serve as a reminder that a candidate selection process should be above suspicion as well as above reproach. I want to assure you that all of us here are well aware of the potential conflicts of interest that can arise during the selection process, and that all of the faculty are committed to bringing into the program the most highly qualified applicants we can recruit. The newest members of our Buckeye family, the colleagues who were selected last September and started in the program this July, are: Dr. Eric Anderson (Creighton University, Omaha, Nebraska), Dr. Pinar Emecen (Hacettepe University, Ankara, Turkey), Dr. Kevin Harrison (Medical College of Georgia, Augusta, Georgia), and Dr. Nidhi Jain (Tufts University, Boston, Massachusetts). We are all very pleased they accepted our invitation to join OSU. Congratulations to Drs. Sam Khoury (’07) and Jeff Wessel (’07), our newest Diplomates of the American Board of Periodontology!! In April we held our annual OSU Perio Research Day, with Dr. Gerald M. Bowers (’62) as the featured speaker. It was a wonderful event, and the several alumni who attended the preceding dinner and Research Day enjoyed both the camaraderie and the presentations from our invited speaker and the residents. Our 2008 graduating class, Drs. Huei-Ling Chang, Pooja Maney, Vlad Shapiro and Jessica Stilley, have all completed their clinical requirements. Drs. Chang, Shapiro, and Stilley have also completed their MS thesis research work and have left Columbus, while Dr. Maney, who is completing her PhD degree research work, will be finishing by the end of the year. Dr. Jessica Stilley, 2007-2008 Chief Resident, whose thesis was on “The effect of local and systemic factors on tongue piercing-associated gingival recession”, presented her research at the recent IADR meeting in Toronto, Canada (July 2-5) and is now in private practice in Florida. Jessica, despite being an ardent Gators fan, has plans to come back to visit OSU before the end of the year. Dr. Ling Chang, whose research was on “Human periodontal clinical phenotypes: Identification VOLUME 11, ISSUE 1 Page 4 Voice of the Director - Continued based on gingival and dental characteristics”, was one of the three Research Forum finalists at this year’s annual Midwest Society of Periodontology meeting in Chicago (February 22-24). This is the third year in a row that our program has had a finalist at this meeting, a testament to the hard work of our residents. Ling, who scored at the 95th percentile among all periodontal residents during this year’s AAP In-Service Examination, resides now in Tennessee and is pursuing private practice opportunities. Dr. Pooja Maney, who presented her work on “Neutrophil formylpeptide receptor genetics and aggressive periodontitis” at IADR, is our newest Orban prize finalist; she will compete during the upcoming AAP meeting in Seattle, WA (September 6-9). Pooja’s participation marks the third time an OSU resident has become an Orban competition finalist since 2004. Pooja is planning to continue on in an academic career, and is already exploring potential faculty positions. Dr. Vlad Shapiro, who also presented his thesis work on “Resonance frequency analysis and biomarkers around one stage dental implants” at IADR, has moved to Cincinnati and is in private practice. Vlad, who during the residency broke all previous clinic production records, has promised to come back and show the new residents how it’s done. Congratulations to Jessica, Ling, Pooja, and Vlad for their accomplishments! The residents and I greatly appreciate your continuing support of the program as we keep on receiving referrals for patients who cannot afford periodontal treatment in a private practice setting or who represent specialized treatment challenges. Should you need to contact the clinic for a patient referral or any other reason, please call 614-2924927. You can always reach me at [email protected] or at 614-292-0371. I know that I do not need to mention to any of you the contributions Dr. Lewis Claman has made to the program over his many years of service at OSU. However, I do want to mention that on December 5th of this year the Division will be hosting a celebration to honor Dr. Claman as he plans to retire in early 2009. Please mark the date and make your travel plans early. I look forward to seeing you all at the Buckeye Reception, which will be held on Monday, September 8 at 5:30 pm in the Madrona Room of the Sheraton Seattle Hotel, during the upcoming AAP meeting in Seattle. Please Join Us Best wishes, Buckeye Reception Dimitris Tatakis AAP Meeting in Seattle Sheraton Seattle Hotel September 8, 2008 5:30 p.m. VOLUME 11, ISSUE 1 Page 5 Predoctoral Director’s Report Lewis Claman, DDS, MS We are excited to report on two major changes in the predoctoral clinical program that have been implemented in the past few months. Periodontal Screening and Recording (PSR) Implementation of the PSR was discussed in the last Cutting Edge. Our objectives in using this system for screening new patients is: To identify patients in periodontal health or with gingivitis, who can be managed by students under the supervision of any College of Dentistry clinical faculty. To identify patients with destructive periodontal diseases who will be comprehensively charted, treatment planned and appropriately referred. To expedite patient treatment by allowing new patients with gingival health or gingivitis to be scheduled in the Primary Care Clinic under the supervision of dental faculty. The Clinic had a smooth transition into the PSR, largely through the cooperation of the Associate Dean for Clinical Affairs, Dr. Stan Vermilyea, the Chair of Primary Care, Dr. Meade Van Putten, the Director of the Screening Clinic, Dr. Joen Ianucci and support staff. Dental students seem to appreciate the opportunity to fast-track patients who are healthy or have problems limited to gingivitis and are very responsive to comprehensive charting, when it is indicated. The Screening Clinic receptionist pages periodontal faculty whenever patients have PSR Codes of 4. At this time, a panoramic radiograph is available. The periodontal faculty then decides whether the patient should be directly referred to the Graduate Periodontics Clinic. All patients with PSR codes of 3 are comprehensively charted in the Primary Care Clinic under the supervision of Periodontal Faculty. Patients with PSR Codes of 0, 1 or 2 may be seen under the supervision of any dental faculty for an adult prophylaxis following an initial plaque score. However, they must have their periodontal status confirmed and treatment plan signed by a periodontal faculty in an appointment before they begin cast restorations, major reconstruction or if there are no major dental needs, before completed treatment can be approved. When the periodontal faculty evaluates the patient, a minimum of bite-wing radiographs are available. Periodontal faculty will confirm the pocket depths and examine for other periodontal problems such as gingival recession, mucogingival defects and esthetic crown lengthening, if these problems have not yet been recognized. We believe use of the PSR has streamlined patient evaluation while an emphasis is placed on evaluating, referring and treating patients with periodontitis and periodontal conditions. Dent Competency Examination and Direct Mentoring Experience We have made major revisions in the Competency Examination for third year dental students. In an effort to stress competency in basic periodontal diagnostic skills, we have gone from a strictly manikin-based exam to one that is patient-based for periodontal measurements and an Objective Structured Clinical Exam for observing basic periodontal examination skills. The critical periodontal skills of probing technique and calculus detection will still be on a manikin, while composite radiographs will be used to evaluate student ability to recognize periodontal bone loss, angular defects, furcation radiolucencies, calculus, caries and defective restorations. To better prepare students for the important Dent 3 competency examination, we have also developed a Direct Mentoring Experience, optional for this year and required next year. The purpose of the experience will be to have full time and part time periodontal faculty guide the student in critical periodontal examination techniques on a patient with signs of periodontal disease. While it is easy to assume each faculty evaluates techniques as they work with students, sometimes, because of time restraints, the results (measurements) are evaluated, but techniques are not observed. In previous clinical competency examinations we have observed students using incorrect techniques, especially for probe placement and exploring for calculus. Since it is not appropriate for faculty to correct techniques during a competency exam, the direct mentoring experience will be a helpful exercise to provide feedback to students before the graded competency exam takes place. VOLUME 11, ISSUE 1 Page 6 Recent Awards to Faculty and Students Purnima Kumar 2008 Educator Award of the American Academy of Periodontology Huei-Ling Chang Honorable Mention Graduate Student Research Forum (Midwest Society of Periodontology 2008) Vladimir Shapiro Second Place Astra Night Research Competition, Columbus OH Pooja Maney Orban Competition Finalist Congratulations Congratulations to Our New Diplomates Samer Khoury ‘07 Jeff Wessel ‘07 Special Recognition Dr. John E. Horton, former Chair and Program Director, Section of Periodontics, has been recognized as the Fifth Distinguished Alumni of the Advanced Training Program in Periodontics, Baylor College of Dentistry. Texas A & M University Health Science Center. Dr. Horton was cited for his "remarkable career as an educator, clinician, and researcher", wherein he established a role for cell-mediated reactions in the pathophysiology of periodontal disease, initially detected the cytokine IL-1 ("osteoclast activating factor"). and provided initial clinical and histological studies on the use of ultrasonic instrumentation in bone surgery. Dr. Horton received his dental training at Tufts School of Dental Medicine, his specialty training in Periodontics at Baylor College of Dentistry, studies in Higher Education at George Washington University, and conducted research at the National Institute of Dental Research and Walter Reed Army Medical Center, prior to his appointment as Professor at The Ohio State University College of Dentistry. He is presently an Emeritus Professor and resides in Columbus, Ohio. Congratulations are in order to Huei-Ling Chang for her excellent performance on the In-Service Exam in 2008! Dr. Chang achieved the 19th highest score among 439 periodontal residents who took the exam nationwide. to all award winners and new diplomates! Page 7 VOLUME 11, ISSUE 1 CHAIRMAN’S CHOICE JENNIFER COUZIN Truth and Consequences FROM SCIENCE When a scientist is accused of falsifying data, what happens to that scientist's lab? As Jennifer Couzin reports, the lab's post-docs and young researchers can pay as much if a price as the wrongdoer. In those first disorienting months, as fall last year turned to winter and the sailboats were hauled out of nearby lakes, the graduate students sometimes gathered at the Union Terrace, a popular student hangout. There, they clumped together at one of the brightly colored tables that look north over Lake Mendota, drinking beer and circling endlessly around one agonizing question: What do you do when your professor apparently fakes data, and you are the only ones who know? Chantal Ly, 32, had already waded through 7 years of a Ph.D. program at the University of Wisconsin (UW), Madison. Turning in her mentor, Ly was certain, meant that "something bad was going to happen to the lab." Another of the six students felt that their adviser, geneticist Elizabeth Goodwin, deserved a second chance and wasn't certain the university would provide it. A third was unable for weeks to believe Goodwin had done anything wrong and was so distressed by the possibility that she refused to examine available evidence. Two days before winter break, as the moral compass of all six swung in the same direction, they shared their concerns with a university administrator. In late May, a UW investigation reported data falsification in Goodwin's past grant applications and raised questions about some of her papers. The case has since been referred to the federal Office of Research Integrity (ORI) in Washington, DC. Goodwin, maintaining her innocence, resigned from the university at the end of February. (Through her attorney, Goodwin declined to comment for this story.) Although the university handled the case by the book, the graduate students caught in the middle have found that for all the talk about honesty's place in science, little good has come to them. Three of the students, who had invested a combined 16 years in obtaining their Ph.D.s, have quit school. Two others are starting over, one moving to a lab at the University of Colorado, extending the amount of time it will take them to get their doctorates by years. The five graduate students who spoke with Science also described discouraging encounters with other faculty members, whom they say sided with Goodwin before all the facts became available. Fraud investigators acknowledge that outcomes like these are typical. "My feeling is it's never a good career move to become a whistle-blower”, says Kay Fields, a scientific investigator for ORI, who depends on precisely this occurrence for misconduct cases to come to light. ORI officials estimate that between a third and half of nonclinical misconduct cases - those involving basic scientific research - are brought by postdoctoral fellows or graduate students like those in Goodwin's lab. And the ones who come forward, admits ORI's John Dahlberg, often suffer a "loss of time, loss of prestige, [and a] loss of credibility of VOLUME 11, ISSUE 1 Page 8 CHAIRMAN’S CHOICE - Continued your publications." Indeed, Goodwin's graduate students spent long hours debating how a decision to alert administrators might unravel. Sarah LaMartina, 29, who gravitated to biology after its appeal outshone her childhood plan to become a veterinarian, had already spent 6 years in graduate school and worried whether all that time and effort would go to waste. "We kept thinking, 'Are we just stupid [to turn Goodwin in]?'" says LaMartina, whose midwestern accent reflects her Wisconsin roots. "Sure, it's the right thing to do, but right for who? ... Who is going to benefit from this? Nobody." Goodwin, in her late 40s, had come to the University of Wisconsin in 2000 from Northwestern University in Chicago, Illinois, and was awarded tenure by UW soon after. Landing in Wisconsin was something of a homecoming for her; she had done a postdoc under Judith Kimble, a prominent developmental geneticist in the same department. Goodwin studied sex determination in worms during their early development and has published more than 20 papers on that and other subjects in various prominent journals (including, in 2003, Science). Goodwin was also the oldest of a crop of female faculty members hired in recent years by genetics department chair Michael Culbertson. "She was the role model,” he says. In the beginning, the Goodwin lab had a spark. Students recall being swept up in its leader's enthusiasm when, seeking a lab in which to settle, they rotated through for a month during their first year of graduate school. Goodwin pushed her students to be- lieve that compelling scientific results were always possible, boosting their spirits during the low points that invariably strike Ph.D. hopefuls. She held annual Christmas parties at her home west of Madison. Once, she took the entire lab on a horsebackriding trip. Then, last October, everything changed. One afternoon, in the conference room down the hall from the lab, Ly told Goodwin she was concerned about her progress: The project she'd been working on, Ly felt, wasn't yielding usable results. Despite months of effort, Ly was unable to replicate earlier observations from the lab. "At that time, she gave me three pages of a grant [application]”, Ly recalled recently. The proposal, which was under review at the National Institutes of Health (NIH), sought to broaden a worm genetics project that another student, third-year Garett Padilla, had begun. Goodwin, Ly says, told her that the project, on a new, developmentally important worm gene, was "really promising, but there's so many aspects of it there's no way she can work on everything." Goodwin urged Ly to peruse the pages and see whether the gene might interest her as a new project. Reading the grant application set off alarm bells for Ly. One figure, she quickly noticed, was represented as unpublished data even though it had appeared in a 2004 paper published by Goodwin's lab. Ly and Padilla sat back to back at desks in the corridor outside the lab. When she showed him the pages from the grant application, he too was VOLUME 11, ISSUE 1 Page 9 CHAIRMAN’S CHOICE - Continued shaken. "There was one experiment that I had just not done as well as several published and unpublished figures that seemed to have been manipulated”, he says. Two images apparently identical to those already published were presented as unpublished and as representing proteins different from the published versions. "I remember being overwhelmed and not being able to deal with it at that moment”, says Padilla. A bearish 25-year-old with a closely cropped beard and wire-rimmed glasses, Padilla speaks softly, with deliberation. Bored by bench work, he was considering leaving biology research for law school and had discussed the possibility with Goodwin. She had urged him to "stick it out”, he says. "Everybody goes through a phase where they don't want to be here,” he recalls Goodwin telling him. At a loss after seeing the grant application, Padilla consulted two scientists for advice: his fiancée’s adviser, a physiology professor at the university, and Scott Kuersten, a former postdoc in Goodwin's lab who had been dating LaMartina for several years and who happened to be in town. Kuersten and Padilla talked for about an hour and together examined the pages of the proposal. Kuersten, now at Ambion, a biotechnology company in Austin, Texas, advised Padilla to ask Goodwin for an explanation, as did the physiologist. Padilla steeled himself for a confrontation. On Halloween day, he paced nervously outside Goodwin's office, summoning the courage to knock. The conversation did not go well, says Padilla. In a computer log of events he had begun to keep at Kuersten's urging, which he shared with Science, Padilla wrote that Goodwin denied lifting a Western blot image from a published paper and presenting it as unpublished work, although, he added in the log, "She became extremely nervous and repeatedly said, 'I f—-- up.''' Padilla also noted: "I left feeling that no issues were resolved." His confusion deepened when Goodwin later that day blamed the problem on a computer file mix-up. Meanwhile, word was leaking out to others in the lab that something was terribly wrong. Two days later, Padilla called a meeting of all current lab members: six graduate students and the lab technician. To ensure privacy, the group, minus Ly, who had recently had a baby girl, convened in the nearby engineering library. Padilla laid out the grant papers for all to see. In that meeting, ensconced in the library, the grad students hesitated at the thought of speaking with the administration. "We had no idea what would happen to us, we had no idea what would happen to Betsy, we had no idea how the university would react,” says LaMartina, who admits to some distrust of authority and also a belief that people who err deserve a second chance. Ly felt less charitable toward Goodwin but confesses that at first she considered only her own predicament. In many ways, just reaching graduate school was a triumph for Ly, and she badly wanted that doctorate. In 1981, when Ly was 8 years old, her family fled Cambodia for the Chicago suburbs. Around Ly's neck hangs a goldplated French coin, a 20-franc piece VOLUME 11, ISSUE 1 Page 10 CHAIRMAN’S CHOICE - Continued her curator father had collected before he was killed in his country's civil war. In Chicago, Ly's mother worked long hours and put her daughter through Wellesley College in Massachusetts. When Ly moved to Madison, so did her husband, now an anesthesia resident, and her mother, who speaks little English and cannot drive. "Here I am, I've invested so much time in grad school, and this happens. If we let someone know …” she says, her voice trailing off. The students decided that Padilla needed to speak with Goodwin a second time, in hope of extracting a clear account of what went wrong or even a retraction of the grant application. Four days after his first nerve-wracking encounter, Padilla was in Goodwin's office again. This time, the conversation put him at ease. Padilla says Goodwin asked for forgiveness and praised him for, as he wrote in the log, "pushing this issue." She told him that the grant application was unlikely to be funded an assertion that turned out to be untrue given that NIH approved it - but offered to e-mail her NIH contact citing some of the problems in the application. Goodwin subsequently sent that e-mail, on which Padilla was copied. He left the encounter relieved. "At that point, I was pretty content to leave it alone;' he says.”I felt like we had compromised on a resolution." Another student, however, was finding little peace. Mary Allen, 25 and in her fourth year of graduate school, couldn't shake a sense of torment about what her mentor might have done. A bookworm who squeezed 3 years of high school into one and entered college at age 15, Allen is guided by un- ambiguous morals and deep religious convictions, attending a local church regularly and leading a youth group there. She could not fathom that Goodwin had falsified data; at one point, Allen refused even to examine another suspect grant application. But, concerned because Goodwin seemed to have admitted to some wrongdoing, Allen felt she needed to switch labs. Allen alerted Goodwin that she would likely be moving on. Their mentor then began offering additional explanations for the grant application, say Allen and the others. Goodwin told them that she had mixed up some files and asserted that the files had come to her unlabeled. In a private conversation with Allen, she adamantly denied faking data. As November wore on, the lab's atmosphere grew ever more stressful and surreal. When Goodwin was present, she chatted with the students about their worm experiments and their families-the same conversations they'd always had. Yet the strain was taking its toll. LaMartina's appetite declined, and she began losing weight, shedding 15 pounds before the ordeal was over. Padilla called former postdoc Kuersten nearly weekly for advice, and the students talked obsessively with one another. Careful to maintain confidentiality, "the only people we could bounce ideas and solutions off of were each other”, says Padilla. The tension even penetrated Goodwin's annual Christmas party. For the first time, several lab members didn't show up. Deeply worried about how speaking with administrators might impact the VOLUME 11, ISSUE 1 Page 11 CHAIRMAN’S CHOICE - Continued more senior students, lab members chose not to alert the university unless the desire to do so was unanimous. Gradually all, including Ly and LaMartina, the most senior among them, agreed that their mentor's denials left them uncomfortable and concerned that she might falsify data in the future. "My biggest worry was what if we didn't turn her in ... and different grad students got stuck in our position,” says Allen. Two days before exams ended, on 21 December, Ly and Padilla met together with Culbertson and showed him the suspect grant pages. Culbertson didn't know what to think at first, he says, but "when somebody comes to me with something like that, I have to investigate." Culbertson quickly referred the matter to two university deans, who launched an informal inquiry to determine whether a more formal investigation was warranted. As is customary, Goodwin remained on staff at the university during this time. She vigorously denied the charges against her, telling Culbertson and the students in a joint meeting that the figures in question were placeholders she had forgotten to swap out. According to Padilla's log of that meeting, Goodwin explained that she "was juggling too many commitments at once" when the proposal was submitted. Two biology professors ran the informal inquiry, conducting interviews with Goodwin and her students. One of the two, Irwin Goldman, was also a dean, and he became the students' unofficial therapist and news source. At their first meeting in January, Goldman reassured the six that their salaries would continue uninterrupted. The informal inquiry wrapped up a few weeks later, endorsing a more formal investigation. Three university deans, including Goldman, appointed three faculty scientists to the task. At about this time, says Goldman, the university grew uneasy about possible fraud not only in the first grant application that the students had seen but also in two others that had garnered funding, from NIH and the U.S. Department of Agriculture. The school canceled all three grants. After a panicky 2 weeks during which the lab went unfunded, Goldman drew on money from both the college of agricultural and life sciences and the medical school. (Goodwin had a joint appointment at the two.) The students peppered Goldman regularly with questions, seeking advice on whether to talk to a local reporter or how their funding might shake out. Still, because privacy rules prevented sharing the details, "we felt isolated up on our floor”, says Padilla.”There were faculty nearby, but they didn't really know what was going on." Goodwin, meanwhile, all but disappeared from the lab, appearing only once or twice after the investigation began. The students tried to keep up with their projects as they'd always done. They held lab meetings alone before being invited to weekly gatherings with geneticist Philip Anderson's lab. Most faculty members were aware that an investigation had been launched, and some had heard that Goodwin's students were the informers. That led VOLUME 11, ISSUE 1 Page 12 CHAIRMAN’S CHOICE - Continued to disheartening exchanges. A faculty member, asked by one of the students whether they'd done the right thing, told her he didn't know. Rumors reached the students that Goodwin had had "to fake something because her students couldn't produce enough data”, says Ly. In late February, Goodwin resigned. The students say they learned of her departure from a biologist who worked in a neighboring lab. Three months later, the university released its investigation report, which described "evidence of deliberate falsification" in the three applications for the cancelled grants, totaling $1.8 million in federal funds. In the school's report, which university officials shared with Science, investigators also raised questions about three published papers, in Nature Structural and Molecular Biology, Developmental Biology, and Molecular Cell. None has been retracted or corrected so far. "We are considering the implications" of the university report, said Lynne Herndon, president and CEO of Cell Press, which publishes Molecular Cell, in a statement. The editor of Nature Structural and Molecular Biology said she was awaiting the results of the ORI investigation, and the other authors of the Developmental Biology paper are reviewing the relevant data, says the journal's editor in chief, Robb Krumlauf of the Stowers Institute for Medical Research in Kansas City, Missouri. The university investigators also noted other problems in the Goodwin lab. "It appears from the testimony of her graduate students that Dr. Goodwin's mentoring of her graduate students included behaviors that could be considered scientific misconduct-namely, pressuring students to conceal research results that disagreed with desired outcomes and urging them to over-interpret data that the students themselves considered to be preliminary and weak”, they wrote in their report. Goodwin's lawyer in Madison, Dean Strang, disputes the reliability of the school's report. The investigation was "designed under the applicable UW rules to be an informal screening proceeding” and, because Goodwin resigned, "there was no adjudicative proceeding at the administrative level or elsewhere," Strang wrote in an e-mail message. He added that "there are no problems with the three published papers cited in the report (or any others)." Strang declined to address whether Goodwin pressed students to over-interpret data. "Dr. Goodwin will not respond at all to assertions of students in this forum,” he wrote. Culbertson distributed the investigating committee's report to all department faculty members; it even appeared on Madison's evening news. Still, the rapprochement some of the students had hoped for never materialized. "No one ever came up and said, 'I'm sorry”, Padilla says. As the graduate students contemplated their futures this spring, they did have one point in their favor. Ironically enough, the sluggish pace of their projects meant that almost none had coauthored papers with Goodwin. But when several of them sat down with their thesis committees to assess their VOLUME 11, ISSUE 1 Page 13 CHAIRMAN’S CHOICE - Continued futures, the prognosis was grim. Only one student of the six, who did not reply to Science's request for an interview, was permitted to continue with her original project. She has moved to another Wisconsin lab and hopes to complete her Ph.D. within about a year, according to the others. Thesis committees and faculty members told Ly, LaMartina, and fourthyear Jacque Baca, 27, that much of their work from Goodwin's lab was not usable and recommended that they start over with a new doctoral project. The reason wasn't necessarily data fraud, the students say, but rather Goodwin's relentless optimism that some now believe kept them clinging to questionable results. Allen, for example, says she sometimes argued but gave in to Goodwin's suggestions that she stick with molecular data Allen considered of dubious quality or steer clear of performing studies that might guard against bias. Ly, on her third, floundering project, says, "I thought I was doing something wrong experimentally that I couldn't repeat these things." Despite her setback, Baca has chosen to stay at Wisconsin. "It's kind of hard to say" how much time she'll lose, says Baca, who notes that her thesis committee was supportive in helping her find a new lab. The other four - Ly, LaMartina, Padilla, and Allen - have scattered. Only Allen plans on finishing her Ph.D.. Determined to leave Wisconsin behind, she relocated in late March to the University of Colorado, Boulder, where she hopes to start fresh. Members of her church, her husband, and her parents persuaded her to stay in science, which she adores, but she still wonders about the future. "We unintentionally suffer the consequences" of turning Goodwin in, Allen says, noting that it will now take her 8 or 9 years in all to finish graduate school. To her husband's disappointment, their plans for having children have been deferred, as Allen always wanted to wait until she had completed her degree. For Padilla, the experience cemented the pull of the law. In late July, a month after his wedding, he and his wife moved to Minneapolis - St. Paul, Minnesota, not far from where Padilla grew up, because his wife's adviser, the physiologist, had shifted his lab there. Padilla began law school in the city last week. LaMartina spent 2 months in a different Wisconsin genetics lab, laboring over a new worm project she'd recently started under Goodwin. That project, however, fell apart in June. She then spent 3 weeks in Seattle and Alaska with Kuersten. During the trip, LaMartina abandoned her Ph.D. plans, and in July, she left Wisconsin for Texas, joining Kuersten at Ambion as a lab technician. When Ly learned from her thesis committee that her years in the Goodwin lab had come to naught, she left the program and, as a stop-gap, joined a cancer lab as a technician. "I decided that I had put my life on hold long enough,” Ly says. She intends to leave science altogether and is considering business school. For Goldman, the dean who supported the graduate students, the experience was bittersweet. Impressed by the students' professionalism and grace under trying circumstances, he came to VOLUME 11, ISSUE 1 Page 14 CHAIRMAN’S CHOICE - Continued believe strongly that science needs individuals like them. And although he admits that it's "horrible" that so many of the students were told to start over, "I don't see us changing our standards in terms of what a Ph.D. means," he says. Still, Goldman does plan to craft formal policies for students who might encounter this situation in the future. The policies, he says, would guarantee that the university protects students from retribution and that their funding remains secure. He hopes that codifying such safeguards will offer potential whistleblowers peace of mind. In a building with a lobby graced by a fountain shaped like DNA, the Goodwin lab now sits deserted on the second floor. Incubators, pipettes, and empty plastic shoeboxes that once held worms litter its counters. Ly's original fear months before, that something bad would happen to the lab, had proved more prescient than she had imagined. Page 15 VOLUME 11, ISSUE 1 OSU Section of Periodontology 2007 Published Articles (alphabetically, by first author) PEER-REVIEWED ARTICLES 1) DeAngelo SJ, Kumar PS, Beck FM, Tatakis DN, Leblebicioglu B. Early soft tissue healing around one-stage dental implants: clinical and microbiologic parameters. J Periodontol. 2007 Oct;78(10):1878-86. 2) DeAngelo S, Murphy J, Claman L, Kalmar J, Leblebicioglu B. Hereditary gingival fibromatosis--a review. Compend Contin Educ Dent. 2007 Mar;28(3):138-43; quiz 144, 152. Review. 3) Fitzgerald RR, Walters JD. Accumulation of topical naproxen by cultured oral epithelium. J Dent Res. 2007 Aug;86(8):775-9. 4) Kumar PS, Leblebicioglu B. Pain control during nonsurgical periodontal therapy. Compend Contin Educ Dent. 2007 Dec;28(12):666-9; quiz 670-1. Review. 5) Leblebicioglu B, Rawal S, Mariotti A. A review of the functional and esthetic requirements for dental implants. J Am Dent Assoc. 2007 Mar;138(3):321-9. 6) Parashis AO, Tatakis DN. Subepithelial connective tissue graft for root coverage: a case report of an unusual late complication of epithelial origin. J Periodontol. 2007 Oct;78(10):2051-6. 7) Rawal SY, Burrell R, Hamidi CS, Kalmar JR, Tatakis DN. Diffuse pigmentation of maxillary attached gingiva: four cases of the cultural practice of gingival tattoo. J Periodontol. 2007 Jan;78(1):170-6. 8) Rawal SY, Kalmar JR, Tatakis DN. Verruciform xanthoma: immunohistochemical characterization of xanthoma cell phenotypes. J Periodontol. 2007 Mar;78(3):504-9. 9) Silva CO, Almeida AS, Pereira AA, Sallum AW, Hanemann JA, Tatakis DN. Gingival involvement in oral paracoccidioidomycosis. J Periodontol. 2007 Jul;78(7):1229-34. 10) Silva CO, de Lima AF, Sallum AW, Tatakis DN. Coronally positioned flap for root coverage in smokers and non-smokers: stability of outcomes between 6 months and 2 years. J Periodontol. 2007 Sep;78(9):1702-7. 11) Silva CO, Sallum AW, do Couto-Filho CE, Costa Pereira AA, Hanemann JA, Tatakis DN. Localized gingival enlargement associated with alveolar process expansion: peripheral ossifying fibroma coincident with central odontogenic fibroma. J Periodontol. 2007 Jul;78(7):1354-9. VOLUME 11, ISSUE 1 Page 16 ABSTRACTS Chien HH. Effects of Lau-Ya-San on the expression of angiogenesis genes in human gingival fibroblasts. AAP 2007 annual meeting at Washington DC. Chang HL. Clinical periodontal phenotypes: Identification based on gingival and dental characteristics. Khoury S, Thomas L, Sheridan J, Leblebicioglu B. Evaluation of Early Healing Indices Following Implant Placement. J. Dent. Res. 86 (Special issue A): Abstract #520, 2007. May B, Hanke M, Leblebicioglu B, Sheridan J. Effect of mucosal wounding on restraint stress induced catecholamine levels. J.Dent.Res 86 (Special issue A): Abstract # 707, 2007. Paulus B, Leblebicioglu B, Beck FM, Tatakis DN, Mariotti A. Peri-implant health and patient satisfaction. J. Dent. Res. 86 (Special issue A): Abstract #522, 2007. VOLUME 11, ISSUE 1 Page 17 OSU Periodontal Alumnus Profile the Wisconsin Society of Periodontists from 1976 to 1978 and of the Midwest Society of Periodontology in 1986. His most impressive contribution to Periodontics has been through positions he has held in the American Academy of Periodontology, including nine AAP committees. His most notable accomplishments in the AAP include the Executive Committee, the Board of Trustees, and most significantly, President of the AAP (1997-1998). Considered alone, Tim’s accomplishments in the AAP represent an impressive career in public service. What makes his resume most impressive is his parallel service to other dental organizations. In the Wisconsin Dental Association, he was Chair of twelve committees, including the Executive Committee, a member of the Board of Trustees, and Vice President, President Elect and President (1991-1992). We continue to dedicate a section of each issue of the Cutting Edge to recognize the careers of Ohio State Periodontal Alumni, who have had distinguished and unique dental careers. In this issue, we are honoring Dr. S. Timothy Rose, who has had a remarkable career in public service. Another very significant contribution to public service has been Dr. Rose’s prominent role in the American Dental Association. He was Chair of four ADA standing or ad hoc committees, a member of four special committees for the Board of Trustees and a member of the Board of Directors for two ADA foundations. Most impressively, he has held ofDr. Rose received his DDS at Ohio State in fice at the highest levels of the ADA. He was 1967. After completing dental school, Tim on the ADA Board of Trustees from 1993 to was stationed as a dental officer in the US 1997 (i.e 9th District Trustee), ADA President Elect from 1997 to 1998 and ADA President Army. He received his Masters of Science from 1998 to 1999. Moreover, Tim’s preemiand Certificate in Periodontics from Ohio nent prominence in the dental community at State in 1972. He has been in full time private practice limited to Periodontics in Apple- a national level provided a platform for his direct involvement in many contemporary ton, Wisconsin for his entire periodontal career, where he is currently a partner in Valley issues in dentistry. On an international level, Dr. Rose was the World Dental FederationPeriodontics. FDI USA National Secretary from 1999 to 2003 and a delegate to the FDI House of Tim has made a major mark in his career Delegates from 1998 to 2003. through his long and distinguished dedication to service at every level of organized dentistry, where he has been uniquely active Through his leadership dental organizations, Dr. Rose has not only been a representative at local, regional and national levels. His of dentistry at regional, national and internaservice has been in both the General Dentistry arena (principally through the American tional levels, but has also been in contact with other health professions and the general Dental Association) and several periodontal public. He was on the 2000 Governor’s task organizations. Force on the Future of Dentistry in Wisconsin, the 2000 Editorial Board for the U.S DeIn periodontics, Dr. Rose was President of Page 18 VOLUME 11, ISSUE 1 OSU Periodontal Alumnus Profile - Continued partment of Health Report: Healthy People, The Oversight Committee- Surgeons General’s Report: Oral Health Status of the American People (2000), the NIH-NHAINS Study Group (2000) and The NIDCR- National Project for Oral Cancer Awareness. As president of the ADA, he was interviewed about dental issues on the network shows “60 Minutes”, “20/20”, “Dateline” “Good Morning America” and “The Today Show”. He has testified before 7 Congressional Committees on oral health care issues and health care reform. Transcripts of his interviews on oral health and dental issues have appeared in many scientific journals and other publications. Dr. Rose has also pursued scholarly activity. He has been the presenter at 26 continuing education courses on periodontology and dental informatics. Tim was a contributing author on 5 publications in refereed dental journals and one dental abstract. He has participated in five Phase III studies, including testing of local delivery of tetracycline (Actisite®), use of Naproxen for postoperative pain and the use of minocycline microspheres (Arestin®). He has been a member of the Journal of the American Dental Association Editorial Board and the American Journal of Periodontology Editorial Board since 1996. At Marquette University, Tim was a member of the Dean’s Advisory Committee from 1984 to 1998, the Search Committee for Dean in 1985 and the Colleges Building Committee from 1999 to 2002. It is no surprise that Dr. Rose has been the recipient of many honors. At Ohio State, Tim received The Ohio State University College of Dentistry Section of Periodontology Outstanding Alumni Award in 1985 and was the recipient of the OSU College of Dentistry Distinguished Alumnus Award at the Post College Assembly. At local and regional levels Dr. Rose was a recipient of the Wisconsin Society of Periodontists Leadership Award in 1987, the Wisconsin Dental Association Outstanding Dentist Award in 1993, the Distinguished Service Award- Wisconsin Chapter of the American College of Dentists in 1987, The Thomas P. Hinman Dental Association Leadership Award in 1999, the Michigan Dental Association Leadership Award In 1999, and the Wisconsin Dental Association President’s Award in 2000. Nationally, Dr. Rose received the American Society of Periodontists Annual Award in 1967. The Pierre Fauchard Academy Distinguished Service Award in 1997 and most significantly, the 2000 American Academy of Periodontology President’s Award. He is a fellow of four dental honorary organizations and an honorary member of two dental academies. Dr. Rose also has been very active in local community affairs. He has been on the Board of Directors or Board of Trustees of 8 civic organizations, including the Fox Cities Chamber of Commerce, the Fox Valley Arts Alliance and Tri Park Development Corporations. Tim has resided in Appleton, Wisconsin since 1972. He married Virginia (Rogers) Rose in 1963 and has 3 children: Catherine Rose-Peria, Thomas Rose and James Rose. Dr. Rose has several thoughts on his education at Ohio State. "Two of the many memories I have when I think of my post-doctoral training at OSU are first: "The George App Filing System". George had piles of papers, journals, etc. on his desk - an unbelievable amount of paper; yet when you asked him a question he could find the exact document on his desk to explain the issue. It was an amazing process to watch!!!. A second memory is: Dr. John Wolf doing the complement cascade on the blackboard in the seminar room without notes from memory. The process started on one blackboard and extended across three walls of the room. The process is still talked about some 40 years later when those of us that trained with John get together". The Division of Periodontology is proud of Dr. Rose’s many years of dedicated service and numerous honors. VOLUME 11, ISSUE 1 Page 19 AAP Meeting October 2007 Washington D.C. Clockwise from left: Second year perio residents: Pat Kelsey, Stacey Papapostolou, Mabel Salas, and Weiting Ho do the OH-IO!; Group shot of the perio residents at the Straumann Party; third year perio residents Vlad Shapiro, Jessica Stilley, Ling Chang, and Pooja Maney. Group shot of the “boys” in the program. VOLUME 11, ISSUE 1 Page 20 Traditional Thanksgiving dinner at Dr. Claman’s, November 2007 At dinner with the Claman family. The famous Claman turkey! Picture time with Dr. Claman. This is what made all the residents very sleepy after the dinner! VOLUME 11, ISSUE 1 Page 21 Dr. Purnima Kumar’s house warming party, December 2007 Dr. Leblebicioglu and her husband Dr. Bulent Bekcioglu, Dr. Tatakis. Pooja Maney with Drs. John Walters and Anne Walters. Dr. Kumar, Dr. Wei Tatakis, and Mrs. Mariotti. Linda Hallberg-Henson with her parents visiting from Florida. VOLUME 11, ISSUE 1 Page 22 Farewell to Dr. Pinar Emecen, December 2007 The residents and faculty throw a party for Dr. Emecen to wish her farewell back to Turkey and a safe return on July 2008. Dr. Mariotti with Dr. Emecen. Joan Sachs poses with La Romaine. Dr. Tatakis with Deb Hooper. VOLUME 11, ISSUE 1 Page 23 Periodontal Research Day Dinner April 17, 2008 Dr. Bowers, Dr. Kumar, Jessica Stilley, Dr. Claman. Periodontal alumni, faculty, and friends around the table. Dr. Mariotti presents Dr. Bowers with several OSU-themed gifts, including an Ohio State Dentistry t-shirt. Go Bucks!! Dr. Kumar posing with Dr. Mariotti after being presented the 2008 Educator Award from the American Academy of Periodontology. Page 24 VOLUME 11, ISSUE 1 Periodontal Research Day Presentations April 18, 2008 The perio residents pose with Dr. Bowers. Clockwise from left: Jessica Stilley presents her findings of oral piercings; Vlad Shapiro presents wound healing biomarkers of one-stage implants; Pat Kelsey with Jeff Wessel ’07 and Dr. Bowers chatting with the perio residents. VOLUME 11, ISSUE 1 Page 25 Dr. Tatakis’s Barbeque for Residents May 31, 2008 Drs. Dimitris and Wei Tatakis with residents Weiting Ho and Mabel Salas. Pat Kelsey, Vlad Shapiro, and Shaun Rotenberg with family and friends. Irma Iskandar, Stacey Papapostolou, Mabel Salas, and Weiting Ho. Dr. Tatakis and the residents. VOLUME 11, ISSUE 1 Page 26 Dr. Leblebicioglu’s BBQ June 4, 2008 Dr. Chen, Ling Chang, and Weiting Ho. Pooja Maney, Jessica Stilley, Stacey Papostolou, and Dr. Kumar enjoying dessert at the backyard. Linda Hallberg-Henson and Dr. Claman. Perio clinic staff Joan Sachs, La Romine, and Lisa Howard. VOLUME 11, ISSUE 1 Page 27 Graduating Class of 2008 Faculty Club Luncheon June 5, 2008 Dr. Tatakis and the graduating class of 2008: Jessica Stilley, Ling Chang, Pooja Maney, Vlad Shapiro. Staff members and faculty enjoying the lunch. The graduating residents with Dr. Tatakis. First and second year residents with Dr. Leblebicioglu. Page 28 VOLUME 11, ISSUE 1 The New Residents (Class of 2011) Dr. Tatakis welcomes the new periodontal residents at the New Residents Reception. From left: Eric Anderson, Nidhi Jain, Kevin Harrison, Pinar Emecen. The new first year residents pose with Dr. Tatakis at the Medical Heritage Center. VOLUME 11, ISSUE 1 Page 29 Honor Roll of Giving Gifts to the Division of Periodontology can be conferred to the following funds: Endowed Chair for Periodontology: To help ensure the long-term health and stability of the Division of Periodontology at the OSU College of Dentistry, alumni and friends of the division have established a Campaign to raise $1.5 million to create an Endowed Chair in Periodontology. For the division to not only retain outstanding faculty, but to also recruit new faculty to fill the open positions today and in the future, it must distinguish itself even further from the other periodontal programs across the country. One of the best ways to do this is through the establishment of an endowed chair. For more information on what an endowed chair is and does or to talk about your interest in supporting this campaign, please contact Colleen Garland, Director of Development and Alumni Affairs, at (614) 366-4990. The George R. App Periodontal Endowment Fund: Interest from the Endowment is used to support graduate student education and development with special interest in providing funds for travel to meetings by Ohio State University periodontal graduate students. Periodontal Research and Training Fund: This fund is used to support a wide variety of periodontal activities by the Division of Periodontology in the College of Dentistry. More specifically this fund is used for but not limited to the purchase of equipment for the graduate program, support of alumni activities (e.g. the annual AAP Buckeye Reception, CE courses, mailings, etc.), endowment of graduate research projects, purchase of food for graduate student activities, etc. Center for Research in Periodontology: Periodontal research in the Division of Periodontology involves both basic science and clinical science research projects. The Lewis Claman Periodontal Endowment Fund: Interest from the Endowment will be used to support an award for OSU dental students who exhibit clinical excellence in periodontics. Special consideration will be given to students who want to choose a career in academic periodontics. Donors to the Periodontal Endowed Chair Donations and Pledges ($50,000 and up) Dr. Ronald and Mrs. Marcia Garvey Donations and Pledges ($25,000 -$49,999): Dr. Joseph and Mrs. Melanie Koberlein Dr. Winfield and Mrs. Jayne Meek Dr. James and Mrs. Patricia Palermo Dr. Fred and Mrs. Jody Sakamoto Dr. R. Jeffrey and Mrs. Diana Stephens Donations and Pledges ($2,500-$4,999) Donations and Pledges ($1,000-$2,499) Project Advantage Dr. David and Mrs. Renne Cacchillo Dr. Russell Hatfield Dr. John Kukucka Dr. Barry and Mrs. Denise Blank Dr. Laurie McCauley Ms. Helen Dennis Mr. Matt Dennis Dr. Timothy and Mrs. Catherine Coffelt Donations and Pledges (up to $999) Dr. Michael P. Rethman Dr. Charles and Mrs. Doris Solt Dr. Timothy and Mrs. Moore Dr. Binnaz Leblebicioglu Dr. Lewis and Mrs. Nancy Claman Dr. Thomas J. and Mrs. Michelle Miller Total Pledges and Gifts: $217,000 Goal: $1,500,000 Balance: $1,283,000 For more information, please do not hesitate to contact our development office at 614-366-1393 or visit our website at http://dent.osu.edu/alumni/support.php. VOLUME 11, ISSUE 1 Page 30 Upcoming Events September 6-9, 2008 American Academy of Periodontology Annual Meeting, Seattle, WA October 18, 2008 Ohio Academy of Periodontists, Columbus, OH December 5, 2008 Dr. Lewis Claman’s Retirement Party, OSU Faculty Club, Columbus OH February 26-28, 2009 Academy of Osseointegration, San Diego, CA February 28-March 1, 2009 Midewest Society of Periodontology Meeting, Chicago, IL It’s Noteworthy the Cutting Edge is available electronically! If you would like to receive it by email, please email us at [email protected] and let us know where you would like it delivered. It can also be accessed on the web. We encourage all alumni of our program to visit The Division of Periodontology on the OSU College of Dentistry website. The website has been recently updated and is very detailed. 1. The web address of the college is http://dent.osu.edu 2. Click on Academic Sections 3. Click on Periodontology and you will be at the Periodontal Homepage You can then navigate to the Division of Periodontology’s History, Faculty, Staff, Predoctoral Program, Postdoctoral Program, Research, Service, Continuing Education, Alumni, Patients and the upcoming Volpe 2009 competition. To access current or past Cutting Edge issues: 1. Click on alumni 2. Click on the Cutting Edge 3. Click on any issue to open or download. The direct Web address for the Cutting Edge is: http://dent.osu.edu/perio/alumni_the_cutting_edge.php The Buckeye Periodontal Alumni Newsletter building on the past - shaping the present - charting the future WE’RE ON THE WEB! http://dent.osu.edu/perio/ alumni_the_cutting_edge.php OSU College of Dentistry Section of Periodontology Postle Hall 305 W 12th Ave - Room #4129 Columbus, OH 43210 Meter: 21550-011000-61801-10000 E4A11