2010 Fall/Winter - Children`s Diabetes Foundation

Transcription

All Carousel of Hope photos: © Berliner Studio
children’s diabetes foundation at denver — WINTER 2010
STUNNING PERFORMERS
dazzle THE 19th CAROUSEL
OF HOPE BENEFITING
children’s diabetes
foundation
I
conic artists Jennifer Lopez and Marc Anthony, Gladys Knight, Akon and Jay Leno joined with Honorees Maria Shriver and Quincy Jones and presenters
Tom Hanks, Rita Wilson and Randy Jackson, Producer
George Schlatter and Music Director Rickey Minor to
make the 2010 Mercedes-Benz Carousel of Hope the
most glittering, glamorous and gorgeous event in the
24-year history of The Carousel of Hope benefiting the
Barbara Davis Center for Childhood Diabetes and the
Children’s Diabetes Foundation.
(Continued on Page 10)
The Carousel of Hope
1.
3.
4.
6.
1. Jay Leno
2. Maria Shriver, Honoree
3. Jane Fonda
4. Dana Davis, Barbara Davis
5. Raquel Welch
6. Kenny Rickel, Paul and Lynn Palmer,
Isabella and Mariella Rickel, Nancy
Davis Rickel
ON THE COVER
1. Tom Hanks, Rita Wilson,
Barbara Davis, Maria Shriver,
George Schlatter
2. Halle Berry
3. Marc Anthony and Jennifer Lopez,
Featured Performers
2
2.
5.
2.
3.
5.
4.
6.
1.
1. Garcelle Beauvais
2. Gladys Knight, Featured Performer
3. Clive Davis, Stevie Wonder,
Barbara Davis
4. Nancy O’Dell
5. Kelly & Don Johnson
6. Barbara Davis, Daisy Fuentes
3
1.
3.
1. Qunicy Jones, Honoree
2. Cheryl Tiegs, Frances Fisher
3. Garcelle Beauvais, Paul Sorvino
4. Larry Gilman, Donna Mills
5. Gladys Knight, Lisa Raye McCoy
6. Vanna White
7. Don Rickles, Kathy Griffin,
Bob Newhart
4
2.
4.
5.
6.
7.
3.
2.
4.
5.
6.
1.
1. Bob Evans & Guest
2. Jennifer Lopez
3. Bob Daly, Barbara Davis,
Carole Bayer Sager
4. Harrison Fuller
5. Lara Spencer
6. Nigel Lythgoe, Alana Stewart,
Marc Anthony
5
1.
3.
4.
6.
1. Halle Berry, Olivier Martinez
2. Berry Gordy, Eskedar Gobeze
3. Percy Gibson, Joan Collins
4. Sidney and Joanna Poitier
5. George and Jolene Schlatter
6. Brandy, Maksim Chmerkovskiy,
Lisa Rinna, Harry Hamlin
6
2.
5.
2.
3.
4.
1.
5.
6.
1. Barbara Davis, Adrien Brody
2. Akon
3. Sela Ward
4. Alan Thicke, Tanya Callau
5. Paris Hilton
6.
Dr. Nancy Larco, Head of Diabetes at
Medecine Interne Maladies
Metabolique and Dr. Philippe Larco,
leading Haitian Immunologist, who
returned to Port au Prince the day
after the Ball to help with the Cholera
epidemic
7
1.
2.
3.
4.
5.
1. Rickey and Karen Minor
2. Barbara Davis, Steven Graham
Angelica Huston
3. Christopher Backus, Mira Sorvino
4. Gregg Davis, Barbara Davis,
Harry Davis, Elena Davis,
Hudson Davis, Julie Davis
5. Kathy and Rick Hilton
6. Robert & Kelly Day
8
6.
2.
3.
4.
5.
6.
1. Jackie Collins, Dieter Abt
2. Julie Chen, Les Moonves, Leah Remini
3. Marc Anthony
1.
4. Savannah Robinson
5. Randy Jackson
6. Lili Zanuck, Barbara Davis,
Sherry Lansing
9
(Continued from Cover)
More than 1,000 guests attended
the 2010 Carousel of Hope Ball
presented by Mercedes-Benz,
raising nearly $2.4 million
for research and clinical care
programs for diabetes at the
Barbara Davis Center for
Childhood Diabetes, where over
5,000 children and adults receive
care.
The evening would not be
possible without the help of
genius TV veteran, George
Schlatter and his skilled
production crew, talented
music director, Rickey Minor,
and Jay Leno, who once again
reprised his role as the Master of
Ceremonies.
The Children’s Diabetes
Foundation would like to thank
the evening’s presenting sponsor
Mercedes-Benz USA, and major
sponsors GUESS?, American
Airlines, sanofi-aventis U.S.,
The Beverly Hilton Hotel and
our angel sponsors Ron Burkle,
Sarah Siegel-Magness and Gary
Magness and Robert and Kelly
Day. Reem Acra illuminated
the ballroom with her beautiful
donated tablecloths in shades of
pink. Lush flower arrangements
with over 10,000 flowers flown
in from Ecuador were created
by Fred Gibbons of Treefrogs,
who has served as the event’s
exclusive florist since 1990.
We also thank Angelica Huston
for allowing us to use the
sculptures of the late beloved
Robert Graham for the honoree
awards, and Moët Hennessy
USA, our exclusive spirits
sponsor. The evening was also
generously supported by many
corporations and leaders from
the entertainment industry.
The show began with Savannah
Robinson’s a capella rendition
of the “Star Spangled Banner.”
Tom Hanks and Rita Wilson
then introduced First Lady of
California, Maria Shriver, who
was the recipient of the Brass
10
Ring Award for her inspiring
humanitarian efforts. Maria’s
meaningful speech deeply
touched the audience. Last
year’s Brass Ring honoree,
Clive Davis, followed with a
warm introduction of Barbara
Davis who generously thanked
every guest for attending and
joining in the fight against the
global epidemic of diabetes.
She updated the audience on
the Center’s programs and
the advances being made for
children everywhere. In closing,
she mentioned a quote from
Christopher Reeve, “Once you
choose hope, all things are
possible.” American Idol’s
Randy Jackson welcomed Quincy
Jones to the stage as he was
honored with the Foundation’s
distinguished Humanitarian
Award on the 25th Anniversary of
“We Are The World.”
The unforgettable evening
included performances by great
artists Jennifer Lopez and Marc
Anthony, who performed a duet
of “No Me Ames.” Together the
couple sang in perfect harmony
lighting up the room with love
and song. Jennifer Lopez then
took control of the stage in a
fiery performance of “Let’s Get
Loud”, which set the tone for
the evening of entertainment as
each person in the room was
singing and dancing. American
R&B singer and songwriter
Akon was next as he ruled the
stage, performing his hit songs
“Angel” and “Sexy Chick.” The
Featured Performer, legendary
artist Gladys Knight’s grand
finale had guests on their feet,
swaying and singing with her
to classics “Neither One of Us”
and “Midnight Train to Georgia”
leaving everyone euphorically
wishing for more.
Some of the many celebrated
guests included: Halle Berry,
Stevie Wonder, Adrien Brody,
Jackie Collins, Joan Collins
and Percy Gibson, Clive Davis,
Jane Fonda, Berry Gordy,
Kathy Griffin, Tom Hanks and
Rita Wilson, Anjelica Huston,
Randy Jackson, Rickey Minor,
Les Moonves and Julie Chen,
Dermot Mulroney, Bob and Ginny
Newhart, Joanna and Sidney
Poitier, Don and Barbara Rickles,
Carole Bayer Sager and Bob Daly,
Jolene and George Schlatter,
Judge Judy Sheindlin, Rod Stewart
and Penny Lancaster, Sela Ward,
Raquel Welch, Vanna White,
Garcelle Beauvais, Thora Birch,
Brandy, Maksim Chmerkovskiy,
Billy Davis & Marilyn McCooDavis, Bob Evans, Frances
Fisher, Daisy Fuentes, Lisa Rinna
& Harry Hamlin, Nicky Hilton,
Paris Hilton, Rick & Kathy Hilton,
Beverly Johnson, Don Johnson,
Tamala Jones, Susan Lucci, Nigel
Lythgoe, Chris Massey, Kyle
Massey, Benny Medina, Donna
Mills, Nancy O’Dell, Sumner
Redstone, Leah Remini, Mimi
Rogers, Mira Sorvino, Paul
Sorvino, Lara Spencer, Alana
Stewart, Alan Thicke, Cheryl
Tiegs, Louis van Amstel, Buzz
Aldrin, Joan van Ark and Ben
Vereen.
During the live auction one lucky
winner walked away with the
stunning Mercedes-Benz 2011
CL63 AMG for $170,000. The
live auction also included two
incredible trips courtesy of St.
Regis Hotels, one throughout
Europe and another to Hawaii
and Tibet, with airfare to begin
and end the trips donated by
American Airlines. The Silent Auction, chaired by
Nancy Davis and Dana Davis,
was composed of nearly 450
items and included an Avjet trip
for 7 to Las Vegas or Monterey
on a Gulfstream 150 or Hawker
800XP. Other vacation spots
included stays at The Resort
at Pelican Hill in Southern
California, the Peninsula Hotel
in Hong Kong, Hotel Le Bristol
in Paris and the Grand Wailea
Resort Hotel and Spa in Hawaii.
Lavish dining experiences
included: dinner for 20 in the
private dining room at Mr. Chow,
Wolfgang Puck dinner for 12 at
CUT with wines; Il Piccolino;
Toscana; Chateau Marmont; The
French Laundry. Fashion items
this year featured donations
from many fashion icons such as
Donna Karan, Giorgio Armani,
Chanel, Monique Lhuillier, Oscar
de la Renta, Fendi, Devi Kroell,
Saks Fifth Avenue, Neiman
Marcus and more. Other Auction
items included donations from
home teams the LA Lakers,
and LA Dodgers; jewelry from
Tiffany & Co. and Nancy Davis’
Peace and Love; and the popular
Art Gallery with art donated by
leading contemporary artists
such as Ed Ruscha, the late
1.
Dennis Hopper, Tony Bennett,
Ross Bleckner, Nancy Ellison,
Frank Gehry, LeRoy Neiman,
Firooz Zahedi and many more.
Celebrities once again helped
in several ways, including
MAKE LOVE NOT TRASH totes
personally signed by Kenny
“Babyface” Edmonds, Selma
Blair, George Clooney, Clint
Eastwood, Harrison Ford,
Scarlett Johansson, Bill Maher,
Julia Louis-Dreyfus, Mike Myers
and Ben Stiller. Handbags
for Hope was supported by
celebrities Shirley MacLaine,
Maria Shriver, Kelly Preston,
Cindy Crawford, Angela Bassett,
Candice Bergen, Carol Burnett,
Joy Behar, Goldie Hawn, Jackie
Collins, Anjelica Huston,
Julianne Moore, Thora Birch and
Joan van Ark who donated one
of their special handbags and
autographed key chains by Linea
Pelle and Braggables.
Brand new this year was Canvas
for the Cure, a project that
featured original miniature
canvases painted by celebrities
including art by John Travolta,
Anjelica Huston, Josh Groban,
George Clooney, Cindy Crawford,
Bill Maher, Penny Marshall,
Crystal Bowersox and many
more.
This year’s wonderful gift bags
designed by GUESS?, included an
extraordinary array of generous
gifts from GUESS? including
a scarf, eyewear, men’s and
women’s watches, also donations
from the Los Angeles Lakers’,
MAC, The Walt Disney Company,
Jackie Collins, Urban Behavior,
Tina Sinatra, Wen, Carita USA,
Decléor, Avjet, Amanda Dunbar,
Bagatella Handbags, Beverly
Hills Plastic Surgery, Canvas
Pop, M Salon, OPI, Nubius
Organics, Raven Spa and the
Ranch.
The Carousel of Hope has
raised more than $75 million
since 1978 to critically combat
the diabetes epidemic, which
afflicts one in three babies born
today. These essential funds are
raised by Children’s Diabetes
Foundation to fund programs for
more than 5,000 children and
adults who receive specialized
care for diabetes management
and prevention of complications
and on reaching for the cure.
1. Barbara Davis
2. Mavis & Jay Leno
2.
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2010 Symposium
The carousel of hope diabetes symposium
t
he 2010 Carousel of Hope Diabetes Symposium, “Pathways for Future Treatment
and Management of Dabetes,”
addressed new insulin delivery
systems including continuous
glucose monitoring. It also
concentrated on new oral
medications for type 2 diabetes
along with the emerging increase
in obesity and type 2 diabetes in
children and young adults. The
Symposium assembled a group of
experts whose work engages with
the multi-faceted challenges facing
the implementation of this new
technology to benefit of people
with diabetes.
Jeffrey A. Bluestone, PhD, A.W.
and Mary Margaret Clausen
Distinguished Professor; former
Director of the Diabetes Center
at the University of California,
San Francisco at the University
of California, San Francisco, CA
Dr. Bluestone established the
UCSF/JDRF Center for Islet
Transplantation and serves
on the California Institute
for Regenerative Medicine
Diabetes Disease Team, as well
as comprehensive research
and clinical programs aimed
at marrying cutting-edge islet
cell-specific stem cell biology
with novel immunotherapies as a
treatment for type 1 diabetes.
12
Peter Butler, MD, Professor of
Medicine, Chief of the Division
of Endocrinology, Diabetes and
Hypertension and Director of
Larry Hillblom Islet Research
Center, University of California,
Los Angles, CA
Dr. Butler is a clinical investigator
with clinical practice at UCLA
focusing on care of patients with
diabetes and research focusing
on abnormal insulin secretion,
the causes of beta cell death
and the possibility to foster islet
regeneration in humans.
Steve Daniels, MD, PhD
Chairman of the Department of
Pediatrics at the University of
Colorado School of Medicine,
Aurora, CO
Dr. Daniels is a Pediatric
Cardiologist who has focused his
clinical work and research on
Preventive Cardiology. His interests
include the effects of diabetes,
hypertension and obesity on the
cardiovascular system.
Steve Edelman, MD, Professor
of Medicine in the Division
of Endocrinology, Diabetes &
Metabolism at the University of
California at San Diego (UCSD),
CA and the Veterans Affairs (VA)
Healthcare System
Dr. Edelman is also the founder
and director of Taking Control of
Your Diabetes (TCOYD), a not-for-
profit organization with the mission
of educating and motivating people
with diabetes to take a more active
role in their condition.
Dr. George Eisenbarth, MD,
PhD, Executive Director of
the Barbara Davis Center
for Childhood Diabetes and
Professor of Pediatrics,
Medicine, and Immunology
at the University of Colorado
School of Medicine, Aurora, CO
Dr. Eisenbarth first characterized
type 1 diabetes while at Joslin as
a chronic autoimmune disease that
could be predicted prior to clinical
symptoms. His immunogenetics
lab investigates autoimmunity in
natural history studies, including
twins, and in the NOD mouse
with the goal of predicting and
preventing diabetes. He is received
ADA’s 2009 Banting Prize for
Outstanding Lifetime Scientific
Achievement.
Satish K. Garg, MD, MBBS,
DM, Director, Adult Clinic,
Barbara Davis Center, Professor
of Medicine and Pediatrics,
University of Colorado Health
Sciences Center, Aurora, CO
Dr. Garg¹s research interests
include the early detection and
treatment of renal and retinal
complications of type 1 diabetes
and the development of new
diagnostic and therapeutic
Matthias Hebrok, PhD,
Hurlbut-Johnson Distinguished
Professor in Diabetes Research,
Interim Director of the Diabetes
Center, University of California,
San Francisco, CA
Dr. Hebrok’s research focuses on
the understanding of how islets
of Langerhans, the endocrine
component of the pancreas, are
formed during organogenesis, how
their function is regulated in the
mature organism and how changes
in gene expression might allow
islet regeneration.
John C. Hutton, PhD, Research
Director, Barbara Davis Center;
Professor, Department of
Pediatrics and Cellular and
Structural Biology, University of
Colorado Denver, Aurora, CO
Dr. Hutton’s laboratory provides
a strong training environment
in molecular cell biology,
biochemistry and immunology
emphasizing basic research
on insulin secretion and the
pathogenesis of type1 diabetes.
He heads the Diabetes and
Endocrinology Research Center
at the Barbara Davis Center and
the JDRF-BDC Autoimmunity
Prevention Center.
Marian Rewers, MD, PhD,
Clinical Director, Barbara Davis
Center, Aurora, CO
Dr. Rewers is Professor of
Pediatrics and Preventive Medicine
at the University of Colorado and
is a pediatric diabetologist and
an internationally-recognized
physician scientist. He has
made important contributions
to our understanding of the
etiology of type 1 diabetes and
its macrovascular complications
by creating large prospective
cohort studies: DAISY, CACTI and
an international consortium, the
Environmental Determinants of
Diabetes in the Young (TEDDY).
Jay S. Skyler, MD, MACP,
Professor of Medicine,
Pediatrics, & Psychology at the
University of Miami, Miami, FL
Dr. Skyler is Associate Director
for Academic Programs in the
Diabetes Research Institute and
is Chairman of the NIH-sponsored
Type 1 Diabetes TrialNet, an
international network conducting
clinical trials to prevent type 1
diabetes or interdict the type 1
diabetes disease process.
Dr. Robert Slover, MD, Director
of Pediatric Clinical Services,
Barbara Davis Center, Aurora, CO
Dr. Slover is the Colorado principal
investigator (PI) for the STAR 3
study. STAR 3 is a randomized,
multi-center two-arm study
to compare the efficacy of the
MiniMed Paradigm REAL-Time
system versus multiple daily
injections (MDI). He has been
involved in 12 research projects
as either PI or Co-PI, has 12
publications and has been invited
to over 35 speaking engagements.
Phil Zeitler, MD, PhD, Professor
of Pediatrics and Clinical
Science at the University of
Colorado Denver and Medical
Director of the Children¹s
Hospital Clinical Translational
Research Center of the
Colorado Clinical Translational
Science Institute, Aurora, CO
Dr. Zeitler is Attending
Endocrinologist at the Children¹s
Hospital and the Barbara Davis
Center for Diabetes, where he is
Director of the Type 2 Diabetes
and Metabolic Syndrome Clinic
and Director of the Pediatric
Endocrinology Training Program.
He currently serves as Study Chair
of TODAY, a national, NIH-funded,
multi-center trial examining
treatment options for adolescents
with type 2 diabetes and TODAY
Genetics Study. 2010 Symposium
tools related to clinical diabetes
management that include new
insulin analogs and glucose
sensors, etc. He currently
serves as the Editor-in-Chief of
the Diabetes Technology and
Therapeutics Journal.
.
2010 Davis Award Winner
Jeffrey A. Bluestone, PhD
During the past 25 years, Dr. Bluestone has authored over 375
publications on diabetes and immunity while studying the regulation
of T-cells in response to autoantigens and transplantation antigens,
supporting the development of help in the development of a new
generation of tolerogenic drugs that will “turn off” selected parts of
the immune system, leaving the disease-fighting capabilities intact. He has received numerous awards including the JDRF Grodsky Basic
Science Award, the Mary Tyler Moore & Robert Levine Excellence in
Clinical Research Award and a JDRF Scholar Award from JDRF, as
well as the American Society for Transplantation Roche Distinguished
Research Award.
13
Barbara Davis Center
Landmark studies on exercise and
hypoglycemia in youth with Type 1 diabetes
— H. Peter Chase, MD and Rosanna Fiallo-Scharer, MD
T
ype 1 diabetes
is one of the most common chronic diseases in children. Unfortunately, the fear of low
blood sugars (hypoglycemia)
prevents many families from
achieving good control of the
diabetes. Hypoglycemia is
scary, and when severe can
result in seizures or unconscious
episodes. Although exercise is
recommended for all youth with
regular diabetes, hypoglycemia
during or after exercise is one
of the most frequently identified
specific causes of severe
hypoglycemia. Three landmark studies in the
CTRC (Clinical Translational
Research Center) at Children’s
Hospital have been important
in making exercise safe for
children with Type 1 diabetes. The first two studies have been
performed as part of a working
group (DirecNet) of pediatric
endocrinologists at the Barbara
Davis Center/Denver Children’s
Hospital, Yale University,
Stanford University, Nemour’s
Children’s Hospital in Florida,
and the University of Iowa with
coordination by the JAEB Center
for Health Research in Tampa, Fl.
An initial study developed the 60
minute treadmill methodology
used in all later studies. The
initial study found that during
the exercise, one out of four of
the children had blood sugar
levels below 60 mg/dL and half
of the children had values below
70 mg/dL. The children stayed
in Children’s Hospital overnight
to study the incidence of
delayed nocturnal hypoglycemia
(low blood sugar levels). Surprisingly, lows occurred
14
during 48% of nights following
a day when the children had
exercised, and on 28% of nights
when the same youth spent
the night in the hospital after
a day without exercise. This
was published in the Journal of
Pediatrics 147: 5 28, 2005.
An important second study
focused on preventing the
low blood sugars during the
afternoon exercise session. Youth using an insulin pump
turned off the pump (no insulin)
during the 60 minutes of
exercise and for 45 minutes
after the exercise. Low blood
sugars were approximately 1/3
as common when the insulin was
discontinued (16% of children)
as on another day when insulin
was continued for the same
youth (48% low). This was
published in Diabetes Care 29,
2006.
In a third study (currently in
press: Journal of Pediatrics),
Dr. Craig Taplin (a 3rd year
Endocrine-Diabetes fellow
at The Children’s Hospital/
Barbara Davis Center studied
methods to prevent the delayed
low blood sugars during the
night. The same afternoon
exercise program was used as
in the two above studies. He
found that discontinuation of
the insulin during exercise and
administration of half of the
usual insulin for 45 minutes
after the exercise, followed by a
20% reduction of basal insulin
from 9pm to 3am essentially
prevented low nighttime blood
sugars. As these changes in
insulin delivery are only possible
for youth using an insulin
pump, the administration of a
medicine , terbutaline, was also
studied. This can be used by
youth using injections and not
using an insulin pump. This
medicine prevented low blood
sugars at night but caused blood
sugar levels to be too high. Further studies will be needed
to determine the correct dose of
terbutaline. In summary, knowledge from
these three landmark studies,
all done in collaboration with
The Children’s Hospital and
the Barbara Davis Center for
Childhood Diabetes, should help
to make life safer and easier for
the 3,000 children with Type 1
diabetes followed at the Center,
as well as for the millions of
children with diabetes around
the world.
important websites
Children’s Diabetes Foundation
www.ChildrensDiabetesFoundation.org
Barbara Davis Center for Childhood Diabetes
www.BarbaraDavisCenter.org
Juvenile Diabetes Research Foundation
www.jdrf.org
American Diabetes Association
www.diabetes.org
Children with Diabetes
www.ChildrenwithDiabetes.com
— Rita Trujillo Hughes, LCSW, CDE,
Clinical Social Worker
J
SHOTS!”
ust a minute...” “I have to go do something
first....”
“You’re
mean!” “I HATE
Sound familiar? Are shots or
set changes at your house a
struggle and a battle? You are
certainly not alone. Preliminary
study suggests that perhaps
a third of all children, teens
and adults have some degree
of needle anxiety that makes
injections a challenge. However,
the majority of these kids don’t
necessarily say that shots
hurt. Their behavior tells us so. Needle fears range in degree
from mild to severe. True
needle phobia (where the level
of anxiety is so heightened that
people might faint at the sight of
a syringe) is less common, but
needle fearfulness is nonetheless
very important to address. It is
important to know that anxiety
about shots is mediated by a
real biological response. The
physical symptoms are real. Queasy stomach, sweaty palms,
shaky hands, and pounding
hearts are not uncommon.
Sometimes, pain with shots
triggers anxiety that can lead
to difficulties with injections. Incorrect injection technique
may be causing some pain. Though we know that shots
aren’t going to be absolutely
painless 100% of the time,
with proper preparation and
technique, shots should be
relatively pain free most of the
time. Shots ought to feel like a
small pinch (at least that’s what
we strive for). Cold insulin and
some types of insulin might be
contributing to discomfort and
these are issues that your nurse
educator can review with you
and make suggestions that might
make a real difference.
If changing technique doesn’t
work and your child has some
of the following symptoms, then
consulting one of the clinical
social workers on the team
might help. Even when kids
don’t complain of anxiety or
painful shots, these behaviors
suggest that we may need to look
a little closer: * Your child stalls around shots
or has elaborate rituals about
how they should be done.
* Takes a long time to actually
do the injection or “hunts and
pecks” looking for just the right
spot.
* Refuses to rotate sites and has
a favorite spot that usually ends
up puffy from overuse.
* Demands control and refuses
help with injections from anyone,
even when help from a parent
has been recommended by the
doctor.
* “Forgets” to do shots or even
skips some injections.
* A persistently high A1c even
when insulin is increased.
* Young children consistently
cry about shots and parents feel
they have to wrestle with them in
order to get the job done.
When kids anticipate and expect
pain with an injection, they may
begin doing things that actually
heighten their anxiety and their
perception of pain. For example,
they may hold their breath and
tense their body. They may
wiggle and struggle, making it
more difficult for a parent to
do an injection easily. These
behaviors will probably make
shots hurt more and the longer
the struggle continues, the
harder it is to change.
Taming the
Shot Monster
Photo: © Janssen Photography
15
16
Needle Anxiety (Fear
of shots)
It is now known that needle
anxiety of some degree occurs in
almost everyone. Children and
adults have worries about shots. In a person with diabetes, we
used to assume that this anxiety
would just go away because they
had to have shots every day. We
now know that needle anxiety, if
strong, doesn’t “just go away”. There are some things that can
be learned to reduce this anxiety
if we identify it is a problem.
First of all, anxiety about
shots is normal. When we
fear something, we get tense
and hold our breath. Our head
is filled with thoughts about
pain. Parents, who have to
give these shots, can be just as
needle anxious as their child. Remember, that the syringes
that are now used for insulin are
much smaller and have shorter
needles so that shots are much
more comfortable these days. With a few easy techniques,
shots can be less stressful. The diabetes educators in our
clinic always have parents
or significant others practice
injections on each other using
saline solution. The practice
nearly always reassures them
that giving insulin injections to
their child is not the trauma they
image.
Tensing can make shots hurt. So
take a couple of deep relaxing
breaths (“breathe in through
the nose and breathe slowly out
through the mouth”) and try to
image yourself made of jell-o. By relaxing the tension, shots
can be done more comfortably. Sometimes a little distraction
can help refocus the mind from
fear to something else. Watching
cartoons or listening to some
favorite music with headphones
can help the mind from thinking
too much about the shots and
aids
Sometimes a person with
diabetes doesn’t get over their
stress about shots. A few
symptoms that might indicate
this is going on are;
F persistently high HbA1c
F a child wanting to do all their
own shots - particularly when
they want to do the shot in a
room by themselves (some shots
will probably be missed)
F
lack of site rotation
(hypertrophy, or hard tissue at
the injection site)
F missed insulin shots
F excuses for wanting to “put
off” the shot (stalling)
F
parental fear or worry about
injections or blood draws
The psychosocial member of
the team can be very helpful to
children or parents with sorting
out this problem. Treatment can
include behavioral techniques
and purposeful distraction. The
latter includes TV, music, toys,
blowing bubbles and books.
Sometimes injection devices help
the problem (Inject-Ease) though
Photos: © kentmeireisphotography.com
they do not “cure” it. Behavioral
techniques include learning
to relax, reward programs,
systematic desensitization and
biofeedback. As fear of shots,
blood or injury decreases, the
HbA1c usually improves.
The first step in making shots
easier is identifying when kids
are having more anxiety than
they should. If you feel shots
have been too much of a battle
around your house lately, you
might mention that at your next
visit and we’ll see how we can
help.
Research at the BDC and the
Children’s Hospital, put together
an impressive roster with the
following BDC clinical staff:
Physicians:
H. Peter Chase, MD
George Eisenbarth, MD, PhD
Rosanna Fiallo-Scharer, MD Robert Slover, MD
— Regina Reece
t
he Barbara Davis
Center for Childhood Diabetes held its annual, “Taking
Diabetes to School” conference
on Friday, October 15th at the
Nighthorse Campbell Native
Health Building, located at the
CU Anschutz Medical campus. This program was staffed by the
BDC Pediatric Clinic as well as
Michelle Passamaneck of ADA,
Kathleen Patrick of Colorado
Department of Education and Amy
Reeves of Medtronic Diabetes.
There were 90 attendees
ranging from clinic aids to
school principals who enjoyed
an information packed day
where topics included: What
is Diabetes, Psych-Social
Issues, Nutrition Management,
School Health Plans, and the
Importance of a School Nurse.
There were also hands-on
workshops in the afternoon that
covered the following areas: Pumps and Sensors, How to
Handle High and Low Blood
Glucose Levels and training on
various blood glucose monitors
and on how to use syringes and
insulin pens on pediatric patients.
A special appreciation is
expressed to the following
supporters who made this
program possible: Abbott
Diabetes Care, American Diabetes
Association, Animas Corporation,
BD, the Children’s Diabetes
Foundation, the Colorado
Department of Education, The
Guild of the Children’s Diabetes
Foundation, Lilly USA, LLC,
Medtronic Diabetes, Novo
Nordisk, Inc. and sanofi-aventis.
Nurse Practitioner:
Stephanie Kassels, DNP(c), FNPBC, CDE
Nurses:
Georgia Koch, RN, BSN, CDE
Laurel Messer, RN, MPH, CDE, Sarah Morey, RN, BSN Susie Owen, RN, CDE
Kathy Smith, RN, BSN, CDE
Sally Sullivan, RN, CDE
Graciela Tellez, RN
Libbie Tuthill, RN, BSN, CDE
LILLY
CONFeRENCE
— Regina Reece
Type 1 Diabetes ExperienceBased Learning Program
T
he Barbara Davis Center for Childhood Diabetes (BDC) hosted the “Type
1 Diabetes Experience-Based
Learning Program” for Lilly USA,
LLC (a company that develops,
manufactures, markets and
sells pharmaceutical and animal
health products).
This two day program held
on October 19-20, 2010 was
designed to aid the Lilly team of
50 individuals from the basics
of, “What is Diabetes?” to the
most current technology in the
diabetes realm such as using
Continuous Glucose Monitoring
devices (CGMs).
Conference Director:
Georgeanna Klingensmith, MD,
Director of Pediatric Clinical
Care and Translational Clinical
Social Workers:
Lisa Meyers, LCSW, CDE
Dana Shepard, LCSW
Rita Trujillo Hughes, LCSW, CDE
Dietitians
Loise Gilmer, MD, RD, CDE
Gail Spiegel, MS, RD, CDE
Participants also attended a
breakout session that provided
the opportunity to have hands
on experience with essential
diabetes care tasks that families
need to master in order to safely
manage diabetes at home. These
tasks included insulin injections,
blood glucose monitoring
and recognition of mild and
moderate hypoglycemia as
well as the treatment of severe
hypoglycemia with glucagon.
Taking
Diabetes
to School
Conference
Photo: © Janssen Photography
We also had a unique
opportunity to present a patient
and parent panel session where
case scenarios were given, as
well as have a question and
answer session during this time.
The BDC is looking forward to
offering this program with Lilly
in 2011.
17
Dr. Slover named new director
of pediatric services
— Marian Rewers, MD, PhD, Clinical Director for Barbara Davis Center for Childhood Diabetes
W
e are proud to announce great news on the search for the new Director of
Pediatric Diabetes Services at
Barbara Davis Center and The
Children’s Hospital Denver.
After months of an intensive
search process that included
several excellent candidates,
the position was offered to
Dr. Robert Slover, Associate
Professor of Pediatrics. Dr.
Slover is expected to take the
new position on January 1,
2011.
Rob Slover earned his MD degree
from the University of Utah
Medical School in 1975. He did
his pediatric training here, at the
Fitzsimons Army Medical Center
in 1975-1978, and is a graduate
of our Pediatric Endocrinology
and Diabetes Fellowship
program (1980-1982). Rob
has been on the faculty of the
School of Medicine, University of
Colorado, since 1990 and on the
BDC faculty since 1994. For the
past five years, he has served as
the Deputy Director of Pediatric
Diabetes Services. His research
interests include Continuous
Glucose Monitoring, artificial
pancreas, Cystic Fibrosis related
diabetes and transition care,
among many others. Rob is
an outstanding clinician and
educator.
One of the main tasks facing
Rob and all of us is to further
strengthen our collaboration
with Children’s Hospital,
Denver’s increasing patient load,
both ambulatory and inpatients,
and with increasing complexity
of diabetes care.
We look forward to working
18
Photo: © Martin Crabb
closely with our TCH-based
colleagues and with multiple
children’s services to optimize
our efforts for the benefit of
children and young adults with
diabetes. We congratulate Dr.
Slover in his selection for this
important leadership position.
On behalf of the Barbara
Davis Center and Children’s
Diabetes Foundation, we would
like to thank Dr. Georgeanna
Klingensmith for 17 years of
her outstanding service as
the Director. Georgeanna has
chaperoned the Service through
challenging times. First, she led
the consolidation of outpatient
diabetes services at the BDC in
1994. More recently, Georgeanna
has been instrumental to
establishing excellent Pediatric
Diabetes Services on the
campus. The clinic volume
has quadrupled under her
watch and so has the staff and
funding. I’m happy to tell you
that Georgeanna is staying at
the BDC and agreed to continue
many of her current activities,
including patient care, teaching,
leading the T32 training grant
and working as the principal
investigator on several studies,
e.g., PDC and Exchange.
Marian Rewers, MD, PhD, Professor,
Pediatrics & Preventive Medicine,
Clinical Director, Barbara Davis Center
for Childhood Diabetes.
I
s your child a patient at the
Barbara Davis Center? Are you a patient at the
Barbara Davis Center? Do
you have a special interest in
diabetes? This is an opportunity
for you, your family and your
friends to have a presence at the
Center by purchasing a place on
the donor wall, or naming rights
on a room — a lasting symbol
of your support. Help Us Catch
the Brass Ring — a Cure for
Diabetes. Levels 1, 2 and 3 will
also be entitled to naming rights
on a room at the Barbara Davis
Center. For information call
Chrissy at 303-863-1200.
Funding
Opportunities:
Level 1
$50,000 and above
Level 2
$30,000 to $49,999
Level 3
$10,000 to $29,999
Level 4
$1,000 to $9,999
Level 5
$100 to $999
donor wall form
Name ________________________________________________________
Address ______________________________________________________
City _____________________________ State ______ Zip_______________
Home phone _____________________ Work phone ____________________
Cell phone ___________________ E-mail ____________________________
Amount $___________________
_____________________________________________________________
(Name as you wish it to appear on donor wall)
Make check payable to Children’s Diabetes Foundation or
q Visa
q Mastercard
q American Express
Name on card _________________________________________________
Card # ________________________________________________________
Mail payment to:
Children’s Diabetes Foundation — Donor Wall 777 Grant St., Ste. 302 Denver, CO 80203
Barbara Davis Center at fitzsimons
donor wall
Photo: © Steve Groer Photography
19
Questions and Answers
20
QUESTIONS AND
ANSWERS
— H. Peter Chase, MD
Q:
A:
What is the
main cause of
low-blood
sugar seizures
in youth and
can they be prevented?
Preceding exercise is described as the main recognized
contributing factor for severe
hypoglycemia in youth. Prevention involves “thinking
ahead.” People using injections
need to reduce insulin dosages
both for the time of exercise
and for the night. Extra snacks
may be needed. People using
insulin pumps can use a “0” to
50% temporary basal during the
exercise (sometimes beginning
30 minutes before), and an 80%
temporary basal rate from 9 p.m.
to 3 a.m. The use of a continuous
glucose monitor (CGM) with
alarms for lows can also be very
helpful in prevention.
Q:
My doctor has
found my child
to have high
transglutaminase
antibodies
that are associated with celiac
disease. Does my child need
to have an intestinal biopsy
before considering a gluten
free diet?
— From Dr. George Eisenbarth, MD, PhD
A:
Children with type 1 diabetes
are at higher risk for celiac
disease, an
illness in which gluten in the diet
from a number of sources (e.g.
wheat) causes the body’s immune
system to attack the inner wall
of the intestine. When children
have severe celiac disease
associated with weight loss and
diarrhea, avoiding gluten usually
makes the symptoms go away
and allows the child to grow
normally. Nowadays we screen
for celiac disease with a simple
blood test for an antibody that
appears in the blood, termed
transglutaminase. If high levels
of the antibody are found, we
recommend a biopsy to confirm
the diagnosis, as celiac disease
is a life-long diagnosis and no
single test is diagnostic. The
biopsy is usually done with
anesthesia so the child is not
conscious for the procedure. A
tube with a camera is swallowed
and at the first part of the small
intestine several pieces of the
intestine are taken through the
swallowed tube, each about the
size of a pencil tip. The biopsy
is then analyzed by the doctors
under a microscope to confirm
a diagnosis of celiac disease
and determine the amount of
intestinal damage, if any.
Many children do not have
symptoms of celiac disease even
though they have antibodies
in the blood. High levels of
antibodies usually indicate that
there is damage to the intestine,
and in general we recommend
biopsy only when the antibody
levels are high, unless there are
also celiac disease symptoms. In many children without
symptoms with high levels of
the antibody there is severe
damage to the intestine. It is
remarkable, but even with severe
damage, with a gluten free diet
the intestine can grow back and
be normal as long as gluten
is avoided. In general with a
diagnosis of celiac disease we
recommend life-long avoidance
of gluten. It is very important
to have a firm diagnosis for
people with symptoms or
high levels of antibodies, and
thus the recommendation for
confirmation through a biopsy.
^
C
^
^
reative juices were flowing at The Guild’s 27th Annual Halloween Party
for Children with diabetes. The
extravaganza took place in the
Green Center at The School
of Mines with the help of the
Phi Gamma Delta Fraternity.
Witches, Pirates, and Buzz
Aldrin himself were seen
decorating pumpkins donated
by Guild Members Robert and
Judy Villano. There were games
and prizes galore as well as
goodie bags filled with toys and
alternative snacks.
The event was a huge success!
No one left the party hungry; the
great people at Pepsi Bottling
Group donated Diet Soda and
Bottled Water and Pizza was
served by Children’s Diabetes
Foundation Volunteers. Face
Painting and Balloon animals
kept everyone entertained
while spooky music and scary
costumes kept everyone on
their toes. Phi Gamma Delta
Fraternity was such a huge
support, supervising games and
putting smiles on the children’s
faces. Big thanks goes out to
Judy McNeil, the Chairman for
The Guild, for all of her hard
work and preparation for this
event. All of the volunteers are
greatly appreciated; without
them, many children would miss
these fun Halloween memories.
Carousel Days
Chills and
Thrills for
halloween
21
The Pink Panther™ & ©1964-2010
Metro-Goldwyn-Mayer Studios Inc.
All Rights Reserved
www.pinkpanther.com
•
12:43
777 Grant Street, Suite 302
Denver, CO 80203
Phone: 303-863-1200 or 800-695-2873
Fax: 303-863-1122
by H. Peter Chase, MD & Laurel Messer, RN, MPH, CDE
2nd Edition
Foundation News
UNDERSTANDING INSULIN PUMPS AND CONTINUOUS GLUCOSE MONITORS
For additional copies of this publication contact:
2nd Edition
The Pink Panther™ & ©1964-2010
Metro-Goldwyn-Mayer Studios Inc.
All Rights Reserved
Book ORDER FORM
Name ____________________________________________________________________________________
Address __________________________________________________________________________________
City/State/Zip _____________________________________________________________________________
Phone (Day) ___________________ Phone (Eve) ______________________ E-mail ___________________
Understanding Diabetes 11th Edition $25 per copy
Quantity ______
Managing and Preventing Diabetic Hypoglycemia (Video) $20 per copy
Quantity ______
Understanding Insulin Pumps & Continuous Glucose Monitors 2nd Edition $15 per copy Quantity ______
A First Book for Understanding Diabetes (English) $10 per copy
Quantity ______
Un Primer Libro Para Entender La Diabetes (Spanish) $10 per copy Quantity ______
All orders must be paid in full before delivery, including $3.00 per order for shipping and handling. Allow one to three weeks for delivery
Make checks payable to: Children’s Diabetes Foundation American Express, Visa, and MasterCard accepted.
Canadian and Foreign Purchasers: Please include sufficient funds to equal U.S. currency exchange
rates and international postage. For additional information call 303-863-1200 or 800-695-2873 or visit
Mailing address: Children’s Diabetes Foundation
Denver, CO 80203
22
by H. Peter Chase, MD & Laurel Messer, RN, MPH, CDE
2nd edition – Understanding Insulin
Pumps and Continuous Glucose
Monitors (CGMs)
— H. Peter Chase, MD and Laurel Messer, RN, MPH, CDE
12:43
•
THE ONLY BOOK AVAILABLE FOR PATIENTS
WITH DIABETES COVERNG BOTH INSULIN
PUMPS AND CONTINUOUS GLUCOSE
MONITORS (CGMs)
2nd Edition
The field of insulin pumps and CGMs is moving so rapidly that
the need for a second edition of this book was imperative. All
chapters are now revised. However, some of the important
changes are listed below:
• An attempt has been made to integrate the teaching about insulin pumps and CGMs – as they complement
each other greatly. Together they are the two major technologies being used for diabetes management
today!
• The chapters in basal rates (Chapter 5) and insulin boluses (Chapter 6) are updated with latest
information – including a figure from a research article published in 2010 showing the importance of giving
boluses 20 minutes prior to meals.
• The advantages of an insulin pump over insulin injections in the prevention of hypoglycemia during
exercise have received a new emphasis.
• The chapter (Chapter 14) on Psychological Aspects offers new ways to deal with pump and CGM issues.
• The overview on CGMs (Chapter 16) deals with important issues including practical methods of CGM (or
insulin pump) adhesive issues.
Foundation News
UNDERSTANDING INSULIN PUMPS AND CONTINUOUS GLUCOSE MONITORS
NOW AVAILABLE
2nd Edition
• Two brand-new chapters were created because readers of the first edition stated they wanted more
information on how to adjust insulin levels based on “Real-Time” CGM readings (Chapter 18) and on
“Retrospective” CGM readings (Chapter 19). These two new chapters provide the information to help any
person/family make the needed insulin adjustments to attain the most optimal glucose control currently
possible. • The research chapter (Chapter 20) includes information relating to recent studies of the “Bionic”
pancreas (using an insulin pump and a CGM) and where current studies are leading future diabetes care.
The new edition is available by calling 303-863-1200 or 800-695-2873 or at www.ChildrensDiabetesFoundation.org
The Pink Panther™ & ©1964-2010 Metro-Goldwyn-Mayer Studios Inc.
All Rights Reserved
23
Photo from 2006 Carousel Ball Journal
One in three
babies born
today will
have diabetes
in their
lifetime.
Your support gives hope for their future.
With love and appreciation, Barbara Davis
Kendall (top photo in pink sweater) was diagnosed with type 1
diabetes, a week after her fourth birthday, in December 2009.
24
Photo: © kentmeireisphotography.com
E
very day in America 35 children are diagnosed with type 1 diabetes -more than one child every hour. Of the 24 million Americans
now afflicted with diabetes, two
million have the most severe
form, type 1, and need insulin
to survive. But insulin is not a
cure. Everyone with diabetes
needs our help to end the
epidemic, and every donation
counts.
The Barbara Davis Center for
Childhood Diabetes (BDC) is
the leading worldwide center
for children and adults with
type 1 diabetes. Your donations
to our annual REACHING FOR
THE BRASS RING: A CAMPAIGN
FOR THE CURE support
Children’s Diabetes Foundation’s
commitment to give all BDC
patients the same high quality
care. No child is turned away. Insulin, supplies and clinic visits
can cost up to $800 or more a
month -- a financial burden for
any family, impossible for the
uninsured and impoverished. Through your gifts we provide
treatment and supplies to nearly
30% of the BDC’s patients who
otherwise could not afford it.
The BDC’s world-renowned
clinical and research programs
include stem cell and islet cell
transplant research, and testing
for genetic and immunologic risk
of diabetes. Trials continue on
a variety of agents, including
a new vaccine trial to prevent
diabetes in those children most
genetically at-risk.
Please, help us catch the
brass ring by supporting our
CAMPAIGN FOR THE CURE. When you help children with
diabetes you empower them to
create a better future for all.
Count me in for a donation of $____________________ Donate online at ChildrensDiabetesFoundation.org/C2C ❏ Enclosed is my check payable to CDF.
My contribution can be matched by my company ___________________________________________________
(name of company)
Charge my credit card: ❏ Visa ❏ MasterCard ❏ American Express
Credit card #__________________________________________________ Expiration date __________________
Name on card _________________________________________________________________________________
❏ I have included CDF in my Will.
Foundation News
REACHING FOR THE BRASS RING
A CAMPAIGN TO CURE DIABETES
Your gift is tax deductible. Tax exempt #: 84-0745008
HELP US GO GREEN!
Register online at www.children’sdiabetesfoundation.org and qualify to WIN An apple iPad!
We need your e-mail address to send e-blasts with the latest news on BDC clinical care and research,
announcements of our activities, and the Children’s Diabetes Foundation’s newsletter, NEWSNOTES. Help
save our planet while we help children with diabetes! A drawing will be made of all e-mail addresses received through January 2011 (whether online or through
the mail). The winner will be announced on our web site in February 2011. Your e-mail address will
never be shared with any individual or organization.
Name/Contact _________________________________________________________________________________
E-mail address ________________________________________________________________________________
Address ______________________________________________________________________________________
City ______________________________________________________ State __________ Zip _________________
Home # _________________________ Office # ________________________ Fax # ________________________
❏ Please remove me from all Children’s Diabetes Foundation mailing lists.
25
Foundation News
MANAGEMeNT
OF DIABETES IN
YOUTH
Photo: © Vail Resorts
July 17-20, 2010
keystone resort and
conference center
M
ore than 400 healthcare providers from all over the country
attended the 11th biennial
conference “Management of
Diabetes in Youth” where they
received the latest information
on the intensive management
of type 1 and type 2 diabetes in
children and adults.
Conference co-directors Marian
Rewers MD, PhD, Clinical
Director of the Barbara Davis
Center for Childhood Diabetes
and Georgeanna Klingensmith,
Chief of the Pediatric Clinic
at the BDC put together an
outstanding roster of renowned
diabetes educators, who along
with BDC healthcare staff,
provided participants with
essential information facing
today’s healthcare providers. Industry sponsored dinners
featured: Lilly USA, LLC (Guest
Speaker: Dr. Henry Rodriguez),
Novo Nordisk (Guest Speaker:
Dr. Asheesh Dewan) and
Medtronic Diabetes (Guest
Speaker: Dr. Fran Kaufman).
Special thanks to the following
Guest Speakers and Sponsors/
Exhibitors for participating
in and providing financial
assistance for this year’s
conference:
GUEST SPEAKERS:
H. Peter Chase, MD, Professor
of Pediatrics, Barbara Davis
Center for Childhood Diabetes,
Professor of Pediatrics,
University of Colorado Denver,
Aurora, CO.
Ron Gill, PhD, Professor
and Research Director of
the Transplantation Institute
Colorado, Aurora, CO.
Johnny L. Ludvigsson, MD,
PhD, Professor of Pediatrics,
Head Physician, Division of
Pediatrics, Linkoping, University
Hospital, Sweden.
Peter Gottlieb, MD, Associate
Professor of Pediatrics at
the Barbara Davis Center for
Childhood Diabetes, Aurora, CO
Henry Rodriguez, MD,
Associate Professor of
Pediatrics, James Whitcomb
Riley Hospital for Children,
Indianapolis, IN.
Irl Hirsch, MD, Professor
of Medicine, University of
Washington, School of Medicine,
Seattle, WA.
Gary Scheiner, MS, CDE,
Integrated Diabetes Services,
Wynnewood, PA.
Lois Jovanovic, MD, Director of
the Samsun Research Institute,
Santa Barbara, CA.
David M. Kendall, MD, Chief
Scientific & Medical Officer,
American Diabetes Association,
Alexandria, VA.
26
Aaron Kowalski, PhD, Program
Manager, Metabolic Protocol/
Research Director, Artificial
Pancreas Project, Juvenile
Diabetes Research Foundation,
New York, NY.
Grace Shih, RD, Packard
Children’s Hospital, Stanford
Medical Center, Palo Alto, CA.
Jay S. Skyler, MD, Professor
of Medicine, Pediatrics &
Psychology, Associate Director,
Diabetes Research Institute,
University of Miami, Miller
School of Medicine, Miami, FL.
Photo: © Vail Resorts
William E. Winter, MD,
Professor of Pathology and
Pediatrics, University of Florida,
Gainesville, FL.
Phil Zeitler, MD, PhD,
Professor of Pediatrics and
Clinical Science, University
of Colorado Denver, Medical
Director, Children’s Hospital
Clinical Translational Research
Center, Colorado Clinical
Translational Science Institute,
Aurora, CO.
PLATINUM
sanofi-aventis U.S. Inc.
Lilly USA, LLC
Bayer HealthCare Diabetes Care
GOLD
Medtronic Diabetes Novo Nordisk, Inc.
SILVER
Abbott Diabetes Care, Inc.
BD Medical/Diabetes Care
BRASS
Animas Corporation
Athena Diagnostics, Inc.
Cumberland Hospital for Children and Adolescents
Diamyd Medical
Insulet Corporation
LifeScan, Inc.
Save the Date!
Keystone Conference
4th Biennial
“PRACTICAL WAYS TO ACHIEVE
TARGETS IN DIABETES CARE”
Friday, July 15, 2011 thru
Saturday July 17, 2011
Foundation News
William V. Tamborlane, MD,
Professor and Chief of Pediatric
Endocrinology, Yale School of
Medicine, New Haven, CT.
Designed to help health care providers caring for
adolescents and adults with diabetes,
Check the Children’s Diabetes and
Barbara Davis Center web sites
in January 2011 for more information.
www.BarbaraDavisCenter.org
Roche Diagnostics
27
Foundation News
28
McDonald Automotive
Carousel classic a wynn/win
N
inety avid golfers and a handful of dedicated volunteers assembled at
the crack of dawn at Signature
Aviation on November 4th to
fly away to Las Vegas to Play
for the Cure at the McDonald
Automotive Carousel Classic to
benefit the Children’s Diabetes
Foundation. A charter Frontier
jet flew the festive group to
The Wynn where they played
on the fabulous Wynn course,
and stayed overnight to enjoy
the Vegas scene while netting
$223,000 to help fund research
at the Barbara Davis Center
for Childhood Diabetes. Led
by Michael McDonald and Dan
Fuller who share a personal
interest in eradicating diabetes,
this event followed the
HealthOne Carousel Classic
held in June at the Cherry Creek
Country Club. The combined
events grossed an astounding
$386,000. We would like to
officially thank our fly-away
sponsors including McDonald
Automotive, Lockton Companies,
Affinity Video, Berco Resources
LLC and Interstate Restorations.
We would also like to thank
our support crew at Frontier
Airlines, The Wynn Hotel, AWG,
Whatzhotnow Catering, everyone
at the Signature Hanger and
all of our golfers. It was a
successful tournament and it
wouldn’t have been possible
without you! This was The
Carousel Classic’s first year
for the Children’s Diabetes
Foundation. Plans are already
underway for 2011 with the
June 29th event at Sanctuary
Golf Course and the fly-away
again at The Wynn early next
November. Rave reviews are
still coming in proclaiming The
Carousel Classic a solid gold
winner!
For further information or to
register for the 2011 events
which are sure to sell out,
contact Amy Cockerham at
303-863-1200.
Save the
Date!
What:
High Hopes Carousel Ball
October 1, 2011
What:
2011 Carousel Classic
Sanctuary Golf Course
June 29th, 2011
What:
The Guild’s High Hopes
Golf Tournament
Glenmoor Country Club
July 18th, 2011
What:
Keystone Conference 4th
biennial “Practical Ways to
Achieve Targets in
Diabetes Care”
July 15-17th, 2011
If a Bead or a Pearl, a piece of Gold or Silver
Would help toward a cure…
Would you give from your jewelry drawer
To raise money to find a cure.
We have started Jewels for Hope
To help save our true ‘Jewels’
Children who live with Diabetes
We are asking you to give a piece of jewelry
Real or costume, it does not matter,
Someone else will treasure it knowing
It will help us toward a cure.
Now won’t you reach into your Jewelry Drawer?
— by Gretchen Pope
To donate contact Susie Hummell at 303-863-1200.
2011
Guild
officers
2010 Guild Officers
President:
Judy McNeil
President-Elect:
Gina Abou-Jaoude
Annual
meeting
Monday, January 10, 2011
Denver Country Club
1700 East 1st Avenue
Denver, CO
Treasurer-Elect:
Gleneen Brienza
Coffee 9:30 a.m.
Meeting 10:00 a.m.
Brunch will be served
following meeting and
program.
Reservation: $35.00
Corresponding Secretary:
Shelley Lucas
Please make your reservation for the brunch by sending a check to:
Immediate Past President:
Sharon Kamen
Attn: Susie Hummell
777 Grant St., Ste. 302
Denver, CO 80203
Recording Secretary:
Jennifer Barrow
Treasure:
Annie Cotton
Advisors:
Sandy Burfitt
Kathy Crapo
Marty Jensen
Gail Johnson
To pay by credit card, please call Susie at 303-628-5109 or e-mail at
[email protected]
T
he Guild of the Children’s Diabetes Foundation is always proud
to award scholarships to high
school seniors and college
students who are current
patients at the Barbara Davis
Center. The scholarship program
was established in memory of
past Guild President, Charlotte
Tucker, who encouraged young
people from the Barbara Davis
Center to follow higher career
and educational pursuits. Guild Guide
Baubles, Bangles and Beads
CHARLOTTE
TUCKER
SCHOLARSHIP
OPPORTUNITIES
FOR 2011-2012
Applications for 2011-2012
will be available in February
2011. Patients who are college
or trade school bound will be
notified regarding applications
in February 2011. If you don’t
receive information or have
questions, please call Susie
Hummell at the CDF office after
February 14th, 2010 at
303-628-5109 or 800-695-2873.
GUILD MISSION
STATEMENT
The Guild of the Children’s Diabetes
Foundation at Denver raises funds for clinical
and research programs for the Barbara Davis
Center for Childhood Diabetes. The Guild
promotes diabetes awareness and education;
assists families in need; provides continuing
education scholarships and sponsors social
activities for children and their families.
å
29
Winner’s Circle
Kids helping
kids
T
hank you Aspen Academy students, faculty and Harrison Fuller for raising $353.00
for Children’s Diabetes
Foundation at your Dress Down
Fundraiser. Your funds will help
to further care and research
programs at the Barbara Davis
Center for Childhood Diabetes
which cares for 5,000 children
and young adults.
A Prayer
Photo: © kentmeireisphotography.com
We are honored to have the
students, faculty and families
of Aspen Academy join us in
the fight against diabetes. We
are especially proud to see kids
helping kids. Your gift has a
very special meaning to our
organization and children with
diabetes. Congratulations on
your very successful fundraiser!
Thank you Harrison for doing
such a great job speaking
on behalf of all of kids at the
Barbara Davis Center at the
Carousel of Hope. We are so
proud of you!
Harrison receives care at the Barbara Davis Center for Childhood Diabetes.
This was his prayer at the Carousel of Hope, October 23, 2010.
Dear God,
Tonight I have a special prayer for all of the children
suffering with type 1 diabetes.
I pray that you keep us brave in our fight, please bless
our parents with patience,
and help the doctors working to find a cure.
I thank you for Barbara Davis and all of the loving
people here tonight supporting kids like me.
In your name we pray, Amen.
Harrison Fuller, Age 7
30
Ingredients
1 cup all-purpose flour
1 cup whole wheat flour 3/4 cup granulated sugar
2 teaspoons baking powder
1/2 teaspoon baking soda
1/2 teaspoon salt
1 15-ounce can 100% pure pumpkin 1/2 cup canola oil
1/2 cup mini semi-sweet chocolate chips
1 cup pecans, very finely chopped 1 teaspoon ground cinnamon
4 large eggs, beaten
1/4 cup 1% low-fat milk
Directions
Preheat the oven to 350°F. Lightly oil or coat a 15 x 10 x 1-inch rimmed baking or jelly roll pan with
nonstick cooking spray and set aside.
Whisk together the all-purpose flour, whole wheat flour, pecans, sugar, baking powder, cinnamon,
baking soda, and salt in a large bowl until well combined.
In a separate bowl, whisk the eggs, pumpkin, oil, and milk until well blended. Pour the liquid
ingredients over the dry ingredients and stir until just combined. Stir in the chocolate chips.
Spread the batter evenly in the prepared pan and bake for 25 minutes, or until a wooden toothpick
inserted in the center comes out clean. Transfer the pan to a wire rack and cool for 10 minutes before
slicing into thirty, 2 x 2½-inch bars.
Tip: For maximum freshness, store leftovers in a plastic container or zip-top bag in the refrigerator.
Nutrition Information per Serving (1 bar):
140 calories, 6g fat (1g saturated, 0.4g omega-3), 95mg sodium, 16g carbohydrate, 2g fiber, 2g protein,
45% vitamin A
Apple Blueberry Walnut Crisp — Makes 6 Servings
Cooks Corner
Chocolaty Pumpkin Bars — Makes 30 bars
Ingredients
3 large Red or Golden Delicious apples (about 2 pounds), unpeeled and cut into 1/2-inch pieces (about 4 cups)
2 tablespoons brown sugar 2 tablespoons whole wheat flour
1 teaspoon vanilla extract
1/2 teaspoon ground cinnamon
1 cup fresh or frozen blueberries
1/2 cup walnuts, very finely chopped
1/2 cup old-fashioned or quick-cooking oats
2 tablespoons brown sugar
2 tablespoons whole wheat flour
2 tablespoons ground flaxseed or wheat germ
1/2 teaspoon ground cinnamon
2 tablespoons canola oil
1/8 teaspoon salt
Directions
Preheat the oven to 400°F. Place the apples, brown sugar, flour, vanilla, and cinnamon in a large bowl
and toss to coat. Gently stir in the blueberries.
Place the apple mixture in an 8 x 8-inch baking pan or dish and set aside.
To make the topping, place the walnuts, oats, brown sugar, flour, flaxseed, cinnamon, and salt in a
medium bowl and stir to combine. Add the oil and stir until the oat mixture is well coated. Spread the
topping evenly over the fruit mixture.
Bake 40 to 45 minutes, or until the fruit is tender and the topping is golden brown (cover with foil about
halfway through if the topping browns too quickly).
Tip: Top each serving with low-fat vanilla frozen yogurt or a dollop of light whipped cream.
Nutrition Information per Serving:
260 calories, 13g fat, (1g saturated, 1.8g omega-3), 55mg sodium, 34g carbohydrate, 5g fiber, 4g protein, 10% vitamin C
31
Nutrition News
What’s The
Scoop on
Sweeteners?
— Gail Spiegel MS RD CDE
T
he following is an
update on the sweeteners that are currently approved by the
food and Drug Administration
(FDA) and available on the
market. The Barbara Davis
Center does not endorse or
condemn any certain product.
Sweeteners can be divided into
two groups based on the calories
they provide. These two groups
are nutritive (contain calories)
and non-nutritive sweeteners (do
not contain calories).
NUTRITIVE SWEETENERS
Nutritive sweeteners provide
calories and carbohydrates and
include two types of sweeteners
that are commonly used: sugars,
sugar alcohols.
SUGARS
Sugar sweeteners include
sucrose (table sugar), fructose,
honey, high fructose corn syrup
as well as others. Sucrose and
fructose are the primary sugar
sweeteners that occur naturally
in the food supply or are added
as sugars in corn sweeteners
and syrups. Sugar sweeteners
provide 16 calories and 4 grams
of carbohydrate per teaspoon.
Agave nectar, which has recently
become popular, is a syrup that
is refined from a cactus-like
plant. Agave nectar is made of
fructose and glucose. Agave is
140 – 160 times sweeter than
sugar. One teaspoon provides
20 calories and 5 grams of
carbohydrate.
32
SUGAR ALCOHOLS
Sugar alcohols include sorbitol,
mannitol, xylitol, erythritol,
isomalt and hydrogenated starch
hydrolysates as well as others. Most sugar alcohols provide
approximately 8 calories and
2 grams of carbohydrates per
teaspoon. Sugar alcohols are
absorbed more slowly than sugar
and eating an excessive amount
can cause diarrhea. Xylitol is
found in a sweetener named
Ideal Sweetener. Sugar alcohols
are found in such products as
sugar free candies, chewing
gum, and baked goods such as
cookies. Despite being labeled
“sugar free” these products still
contain carbohydrates and will
cause a rise in blood sugars. Erythritol is much lower in
calories and carbohydrates than
the others and may not cause
a rise in blood sugars. Be sure
to check the nutrition facts on
the label to determine total
carbohydrate content.
NON-NUTRITIVE SWEETENERS
Non-nutritive sweeteners do
not provide any calories or
carbohydrates. There are
currently five non-nutritive,
artificial sweeteners approved
by the FDA. They are saccharin,
acesulfame-K, aspartame,
sucralose and neotame. In
addition, Stevia, a natural
sweetener does not provide
calories or carbohydrates.
SACCHARIN
Saccharin is 200-700 times
sweeter than sugar. It provides
no calories or carbohydrates
and is not metabolized by our
bodies. It is approved for
use in 100 countries, but has
been controversial here in the
United States. Questions about
saccharin’s safety first began in
1977 when studies suggested it
caused bladder tumors in rats. Saccharin used to carry a warning
on the label, but in 2000 the
National Institutes of Health
removed saccharin from the list
of carcinogens and Congress
removed the requirement for
warning notices. Studies of
high users do not support an
association between saccharin
and cancer. Saccharin can be
found in Sweet’N Low®, Sweet
Twin® and other tabletop
sweeteners as well as fountain
drinks. The amount of saccharin
in each product is limited and
must be printed on the label.
ACESULFAME-K (ACE-K)
Ace-K is 200 times sweeter
than sugar. This sweetener is
not metabolized by the body
either and therefore provides no
calories or carbohydrates. It has
been approved by the FDA since
1988. It is approved for use as
a general-purpose sweetener
and is used in more than 80
countries. Ace-K does not break
down when heated and can be
used in cooking and baking. It
is currently used in sugar free
ice creams and many sugar free
or diet beverages, often times in
combination with sucralose or
aspartame.
ASPARTAME
Aspartame is also 200
times sweeter than sugar. Aspartame is broken down into
aspartic acid, methanol, and
phenylalanine by the digestive
process. The amino acids
phenylalanine and aspartic acid
are metabolized to provide four
calories per gram. Because
this sweetener is very intense
and we use it in such small
amounts, it provides no calories. Aspartame has been approved by
the FDA since 1981. It has been
deemed safe by major health
groups and agencies in over 90
countries, including the World
Health Organization and the
American Medical Association. It is currently approved for use
as a general-purpose sweetener
in all foods and beverages. It
Aspartame has caused the most
controversy and appears to
receive more media attention
about its safety than any other
sweetener. Studies have
not found any link between
aspartame and diseases like
Alzheimer’s or multiple sclerosis. Research has not found that
aspartame leads to an increased
risk of cancer either. The only
negative effects that aspartame
has been shown to cause in a
few small research studies is
worsening migraines for some
patients.
SUCRALOSE
Sucralose was approved by
the FDA in April 1998 for
use as a tabletop sweetener
and in desserts, candies
and nonalcoholic beverages. Sucralose is 600 times sweeter
than sugar and provides no
calories or carbohydrates. It
is made from sucrose, but
is altered so that it is much
sweeter than sugar and is not
absorbed by the body. It does
not break down when heated
and can be used for cooking and
baking. Sucralose can currently
be found in many diet or sugar
free drinks, sugar free ice
cream and other products. It is
marketed under the trade names
Splenda® and Nevella®. Nevella
is sold in regular and probiotic
versions.
than aspartame and 7,00013,000 times sweeter than
sugar. It can be used in baking
and cooking. As of the writing
of this review, neotame was not
found in any products on the
market.
STEVIA
This is a natural sweetener from
the stevia rebaudiana plant
found in South America. Stevia
rebaudiana is an herb that is
300 times sweeter than sugar.
Stevia contains no calories or
carbohydrates and does not
affect blood glucose. Stevia
has been sold in the US in the
supplement aisle for many
years, but in 2008, the FDA
recognized a part of the stevia plant, known as Rebiana or
Reb A, as safe for use in food
products. You can buy stevia in
granular and liquid forms from
grocery and health food stores
for use in drinks, cooking and
baking. Brand names for stevia
include Truvia™ and PureVia™.
Truvia™ contains 3 grams
of carbohydrates per packet,
but the carbohydrates are not
digested or absorbed by the body
according to the company so
they do not affect blood sugar.
Purevia™ contains 2 grams of
total carbohydrate per packet.
Sun Crystals™ is a low sugar
sweetener that is part stevia and
part sucrose (table sugar).
Today, there are more
alternatives than ever for
people with diabetes. Food
manufacturers are using new
sweeteners and combining
sweeteners to improve the
taste and mouthfeel of sugarfree and low-sugar foods and
beverages. Plus, sucrose is no
longer restricted from the diet
and can be included within the
context of a healthy diet. For
those who count carbohydrates,
foods containing sugar can
be substituted for other
carbohydrates in the meal plan
or extra insulin can be given. When it comes to sweeteners,
each family needs to decide what
works best for them.
Nutrition News
breaks down when heated and
does not work well in cooking
and baking. This sweetener is in
many products. Some commonly
used products that contain
aspartame are as follows: Equal,
NutraSweet, NatraTaste, diet
sodas, sugar free JELL-O, light
yogurts, powdered soft drinks,
sugar free ice cream.
NEOTAME
This sweetener was approved by
the FDA as a general purpose
sweetener in 2002. Neotame is
very intense, 40 times sweeter
33
Nutrition News
What’s Considered Safe?
Sugar Substitute
Saccharin
Aspartame
Recommended or Acceptable
Product
Daily Intake (ADI)*
equivalents
5 mg/kg** body weight For 23 kg (50 lb.) child
ADI = 50 mg/kg of body weight
For 23 kg (50 lb.) child
3 packets of
Sweet ‘N Low
33 packets of Equal or
5 cans of diet soda
Acesulfame-K
8 packets
of Sweet One
Sucralose
9 packets of Splenda
1.5 cans of diet soda
*Acceptable Daily Intake is defined as the amount at which there is no adverse effect and a reasonable
certainty that no harm will come from use. It is an amount that you can consume for the rest of your
life with no concern about safety. ADI is set by the FDA and the Joint Expert Committee of Food
Additions of the United Nations Food and Agricultural Organization and World Health Organization.
**1 kilogram = 2.2 pounds
References
Position of The American Dietetic Association: Use of nutritive and nonnutritive sweeteners, Journal of
the American Dietetic Association 2004; 104: 255-275.
Porro, J. Sugar’s Sweet Stand-Ins, Diabetes Interview, Sept. 1998, 74:18-21. Schardt, David. Sweet Nothings: not all sweeteners are equal. Nutrition Action Healthletter, May 2004.
0
Future Newsnotes will be published online at
www.childrensdiabetesfoundation.org.
Remember to register online by January 31, 2011
to qualify to win an I-Pad.
r
34
Executive Board:
Brian Kotzin, M.D.
Vice President, Global Clinical Development, Amgen, Inc.
Thousand Oaks, California
Mrs. Barbara Davis, Chairman
Richard S. Abrams, M.D.
Aké Lernmark, M.D., Ph.D.
Robert H. William Professor, Department of Medicine, University
of Washington School of Medicine, Seattle
Jules Amer, M.D.
Honorary Lifetime Member
Mr. Peter Culshaw
Ali Naji, M.D., Ph.D.
J. William White Professor of Surgery,
Hospital of University of Pennsylvania, Philadelphia
Stephen Daniels, M.D., Ph.D.
Chairman of Pediatrics, The Children’s Hospital, Denver
Gerald Nepom, M.D., Ph.D.
Scientific Director and Director of Immunology and Diabetes
Research Programs, Virginia Mason Research Center, Seattle
Ms. Dana Davis
Mrs. Nancy Davis Rickel
Steven Farber, Esq.
William V. Tamborlane, M.D.
Professor of Pediatrics, Yale University School of Medicine, New
Haven, Connecticut
Richard F. Hamman, M.D., DrPH
University of Colorado Denver School of Medicine
Dean, Colorado School of Public Health
Mrs. Arlene Hirschfeld
Mrs. Deidre Hunter
Mr. Shawn Hunter
M. Douglas Jones, Jr., M.D.
Richard D. Krugman, M.D. Dean, School of Medicine, University of Colorado Denver
Stacy Mendelson Robinson
Ex-officio Member:
George S. Eisenbarth, M.D., Ph.D. Executive Director,
Barbara Davis Center for Childhood Diabetes, University
of Colorado Denver; Professor of Pediatrics and Medicine,
University of Colorado School of Medicine
Scientific Advisory Board:
Richard S. Abrams, M.D.
Associate Clinical Professor of Medicine, University of Colorado
School of Medicine; Rose Medical Center, Denver
Jules Amer, M.D.
Clinical Professor of Pediatrics, University of Colorado School of
Medicine; Partner, Children¹s Medical Center, Denver
M. Douglas Jones, Jr., M.D.
Professor, Department of Pediatrics, University of Colorado
School of Medicine; Section of Neonatology, The Children¹s
Hospital, Denver
Advisory Board:
Mr. Michael Bolton
Sir Michael Caine
Ms. Natalie Cole
Mr. and Mrs. Robert A. Daly
The Honorable Diana DeGette,
U.S. House of Representatives, Colorado
Mr. Neil Diamond
Mr. Placido Domingo
Mrs. Gerald R. Ford
Mr. David Foster
Mr. Kenny G
Mr. David Geffen
Ms. Whitney Houston
Mr. Quincy Jones
Ms. Sherry Lansing
Mr. Jay Leno
Mr. Paul Marciano
Mr. Mo Ostin
The Honorable and Mrs. Bill Ritter, Governor and First Lady of Colorado
Sir Sidney Poitier
Mrs. Ronald Reagan
Mr. Lionel Richie
Mrs. Adrienne Ruston Fitzgibbons
Mr. George Schlatter
The Honorable Arnold Schwarzenegger, Governor of California, and Ms. Maria Shriver
Mr. Steven Spielberg and Ms. Kate Capshaw
Miss Joan van Ark
Ms. Barbera Thornhill
Mr. Gary L. Wilson
Mr. Stevie Wonder
Advisory Board, The Guild Presidents:
Founding President, Amy Davis
Mrs. Jamie Angelich
Mrs. Karen Aylsworth
Mrs. Linda Broughton
Mrs. Joy Burns
Dr. Bonita Carson
Mrs. Nancy Cowee
Mrs. Norma D’Amico
Miss Donna Douglas
Mrs. Margy Epke
Mrs. Chris Foster
Mrs. Helenn Franzgrote
Mrs. Sally Frerichs
Mrs. Debbie Gradishar
Mrs. Helen Hanks
Mrs. Marty Jensen
Mrs. Gail Johnson
Mrs. Sharon Kamen
Mrs. Janet Knisely
Mrs. Suzy Love
Mrs. Sally Newcomb
Mrs. Gretchen Pope
Mrs. Carol Roger
Mrs. Kay Stewart
Mrs. Diane Sweat
Mrs. Melissa Tucker
Mrs. Loretta Tucker
Mrs. Jane Weingarten
Foundation:
Christine Lerner, Executive Director
eeeeeeeeeeee
NEWSNOTES is published twice
yearly by the Children’s Diabetes
Foundation at Denver. We
welcome your comments.
If you would like to submit an
article or a letter to Newsnotes
send information to:
Children’s Diabetes Foundation at Denver
Denver, CO 80203
Cindy Kalkofen
Graphic Designer
Katie Hicks
Christine Lerner
Editors
Know the symptoms of
Childhood Diabetes:
• Loss of weight
• Extreme thirst
• Excessive irritability
• Frequent urination
• Bedwetting
(previously controlled)
Printed on recycled paper
A child reaching for the brass
ring on a carousel is symbolic of
the most important goal of the
— The cure. Your contribution
on behalf of a loved one will
make a difference. It will support
treatment programs to assist
children with diabetes in leading
healthier lives and it will fund
research to help CDF “Catch the
Brass Ring” by finding a cure. Mark an anniversary, birthday,
special occasion; express
appreciation or make a memorial
tribute in honor of someone
special with a contribution — for
any amount — to the Children’s
Diabetes Foundation at Denver. We now accept gifts online.
Donations are tax deductible. Tax ID #84-0745008
The Brass
Ring Fund
Remember a loved one ––
Help CDF “Catch the Brass Ring”
Enclosed is my contribution of $ _______________________
In memory of _______________________________________
Or in honor of _______________________________________
Occasion __________________________________________
Please send acknowledgements to:
(Amount of gift will not be mentioned)
Name _____________________________________________
Address ___________________________________________
City __________________ State ________ Zip ___________
From
Name _____________________________________________
Address ___________________________________________
City __________________ State ________ Zip ___________
Children’s Diabetes Foundation at Denver, Colorado
777 Grant Street, Suite 302, Denver, CO 80203
303-863-1200, 800-695-2873, www.ChildrensDiabetesFoundation.org
35
Nonprofit Org.
U.S. POSTAGE
PAID
Denver, CO
Permit No. 1752
Children’s Diabetes Foundation at Denver, Colorado
Denver, CO 80203
Address Service Requested
BDC EXPANDS TYPE 2 DiabeTES
CARE & RESEARCH IN PARTNERSHIP
WITH CHILDREN’S HOSPITAL
— George Eisenbarth, MD, PhD,
Executive Director of the Barbara Davis Center for Childhood Diabetes
T
here are many forms of diabetes, and for the best clinical care it is important to know which form of diabetes an individual has. In children Type 1 diabetes is the most common and results for autoimmune destruction of the cells that make insulin. While type 2
diabetes is the most common form of diabetes presenting in adults, it is
increasing in children. At the Barbara Davis Center we diagnose and care
for all children with diabetes and there are many forms more than type 1
and 2. In particular, we care for type 2 children at the BDC and Dr. Phil
Zeitler of Children’s Hospital has a specific type 2 clinic at our center. One
of Dr. Slover’s new responsibilities will be to organize care of children at
Children’s hospital who have diabetes due to cystic fibrosis and cancer
therapy. We also are helping to define how many children develop type
2 forms of diabetes with the National Institutes of Health “Search” study
and with studies of the pathology of pancreas of young adults who have
unfortunately died with diabetes (JDRF nPOD international study).
Both type 1 and type 2 diabetes are increasing dramatically. Five to 10
percent of patients with type 2 diabetes have autoimmune type 1 diabetes,
and fortunately, the anti-islet antibody tests we have helped develop now
allow proper diagnosis. Most patients with type 2 diabetes eventually need
insulin. We are studying new therapies applicable to both.

2010 Fall/Winter - Children`s Diabetes Foundation

Transcription

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