Catalog - Merial Rewards

Transcription

Catalog - Merial Rewards
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
catalog
of educational
and supportive materials.
®MERIAL, HEARTGARD, FRONTLINE and the Dog & Hand and Cat & Hand logos
are registered trademarks, ™SPAP and ™Paws to Save Pets and the Paw and
Blue Ribbon logo are trademarks, and SMMerial EDU is a servicemark, of Merial.
©2008 Merial Limited, Duluth, GA. All rights reserved. HGD08PROCATALOG
HEARTGARD ® (ivermectin) HEARTGARD ® Plus (ivermectin/pyrantel)
The true measure of a clinic’s success
is its ability to provide clients the best care
and treatment available. An excellent way
to help achieve this goal is to display
engaging and informative educational
resources in clinic.
The following catalog offers a wide
variety of educational and promotional
internal parasite resources to support
your staff and inform your clients.
Pages 1– 9
In-Clinic Education Tools and Materials
Pages 10–13
Client Take-Home Materials
Pages 14–24
Compliance Aids
Pages 25–30
Product Support Tools for Clinic Staff
HEARTGARD is well tolerated. All dogs should be tested for heartworm infection before starting a
preventive program. Following the use of HEARTGARD, digestive and neurological side effects have
rarely been reported. For more information, please visit www.HEARTGARD.com.
HEARTGARD is well tolerated. In the clinical studies involving more than 3,000 doses of
HEARTGARD for Cats, observations reported within 24 hours of treatment included vomiting in
≤ 0.3% and diarrhea in ≤ 0.2% of the doses administered. There was no statistical difference
between HEARTGARD for Cats and the product vehicle (control) for these observations. For more
information please visit www.HEARTGARD.com.
In-Clinic Education Tools and Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
37:1 Taste Preference Framed Poster
Description:
Framed, high-quality artwork
Benefit:
Educates clients on how easy it is to give
HEARTGARD Plus heartworm preventive
medicine. Also helps support clinic
recommendation for HEARTGARD Plus as
the easy-to-give preventive, which can
help lead to greater compliance.
Target Display Area(s):
Waiting room/reception area, hallways,
exam rooms
1
In-Clinic Education Tools and Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Dogs Playing Poker Framed Poster
Description:
Framed, high-quality artwork
Benefit:
Educates clients on protecting their
pets from deadly heartworm disease and
helps support clinic recommendation for
HEARTGARD Brand Products.
Target Display Area(s):
Waiting room/reception area, hallways,
exam rooms
2
National and State Heartworm Incidence Maps
In-Clinic Education Tools and Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
What’s Eating Your Dog? Poster
Description:
Mounted educational poster
Benefit:
Provides clinic staff and clients the ability
to see all common parasites and where
they are located in the dog.
Target Display Area(s):
Waiting room/reception area, exam rooms
3
In-Clinic Education Tools and Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
National and State Heartworm Incidence Maps
Description:
Mounted (national) and non-mounted
(state) educational posters
Benefit:
Educates clients on the serious risks
and widespread incidences of heartworm
disease in all U.S. states. (National map
includes incidence by state; state maps
include incidence at the county level.)
Target Display Area(s):
Waiting room/reception area, hallways,
exam rooms
4
In-Clinic Education Tools and Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Heartworm Life Cycle Poster
Description:
Mounted educational poster
Benefit:
Educates clients about the heartworm life
cycle and how this dangerous disease
develops and spreads – putting both dogs
and cats at risk.
Target Display Area(s):
Waiting room/reception area, hallways,
exam rooms
5
In-Clinic Education Tools and Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Heartworm Model
Description:
3D clay model of a dog heart
infected by heartworms
Benefit:
A convenient counter tool to aid in
educating clients about heartworm disease
and the risks associated with not using a
monthly heartworm preventive.
Target Display Area(s):
Exam rooms
6
In-Clinic Education Tools and Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Tasty Treat Kit and Refill Bags
Description:
Display unit that contains a jar full of
real-beef, non-medicated tasty treats
Benefit:
Allows vets and clinic staff to demonstrate
to clients just how easy it is to give a monthly
heartworm preventive with real beef.
Target Display Area(s):
Checkout area, reception area, exam rooms
7
In-Clinic Education Tools and Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
FPO
Zoonosis Sandbox Model
Description:
A two-sided box (magnified and non-magnified
view) depicting a mini-sandbox
Benefit:
Assists vets and clinic staff in demonstrating 
how everyday environments can become
contaminated with the eggs and larvae
of roundworms and hookworms.
Target Display Area(s):
Waiting room, exam room
8
In-Clinic Education Tools and Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Open/Closed Sign
Description:
Open/Closed, Hours of Operation branded
window sign
Benefit:
Helpful signage to show clients the clinic’s
hours and remind them about HEARTGARD
and FRONTLINE Brand Products.
Target Display Area(s):
Front door/window
9
Client Take-Home Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Client Brochures
Description:
Color, tri-fold educational brochures
Benefit:
Allows clinics to provide clients with
valuable educational materials in convenient,
easy-to-read brochures on the topics of
heartworms, roundworms, hookworms
and specific HEARTGARD Brand Product
information for both dogs and cats.
Target Display Area(s):
Checkout area, waiting room/reception area,
exam rooms
10
Client Take-Home Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Information Center for HEARTGARD and FRONTLINE® Brand Products
Description:
Product brochure, rebate and
coupon pad holder
Benefit:
A convenient, one-stop materials organizer
for clients.
Target Display Area(s):
Waiting room/reception area, checkout area
11
Client Take-Home Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
The Plus Guarantee* from HEARTGARD Plus Tear Pad
Description:
Tear-off information sheet for clients
Benefit:
Supports clinic recommendations for
HEARTGARD by offering a convenient source
of information about the Plus Guarantee*
from HEARTGARD.
Target Display Area(s):
Checkout area, reception area
*Guarantee void where prohibited by law. Payment obligation by Merial shall be limited solely to that
which is represented in the official Plus Guarantee. Any and all other costs are expressly excluded.
12
Client Take-Home Materials
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Puppy and Kitten Kits
Description:
Starter kit for new puppy/kitten owners
Benefit:
A helpful starter kit with important
information, free samples, coupons and
rebates that vets can offer to new puppy
and kitten owners to help encourage a
long-lasting pet care relationship.
Target Display Area(s):
Checkout area, reception area, exam rooms
13
Compliance Aids
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Calendar/Check-writing Counter Mat
Description:
Counter mat
Benefit:
A helpful reference tool for clinics that offers
a 2-year calendar and check-writing surface.
Target Display Area(s):
Checkout area, reception area
14
Compliance Aids
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Rebate/Coupon Pads
Description:
Tear-off $5 rebate pads
Benefit:
A helpful, money-saving offer on the
purchase of 12-packs of HEARTGARD Brand
Products that clinics can offer to clients to
help encourage year-round use and promote
monthly compliance.
Target Display Area(s):
Checkout area, reception area
15
Compliance Aids
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Email Reminder Pads
Description:
Tear-off and sticky-back reminder pads
Benefit:
A helpful take-home tip that clinics
can offer to clients on how to sign up
for monthly email reminders to give
their dog or cat HEARTGARD, and help
encourage monthly compliance.
Target Display Area(s):
Checkout area, reception area
16
Compliance Aids
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Appointment and Reminder Cards
Description:
Useful appointment and reminder cards
that can be provided/mailed to clients;
available in three versions to meet your
printing requirements (3-Up, 4-Up
and Pinfed)
Benefit:
Aids clinics in supporting pet health
and compliance by reminding clients of
scheduled appointments or alerting them
when it is time to make an appointment.
Target Display Area(s):
Checkout area, reception
17
ComplianceAids
Aids
Compliance
® ®
®
®
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
HEARTGARD Chart Stickers
Description:
Stickers used to indicate that a pet
is currently on HEARTGARD
Benefit:
Provides a quick visual reference in a pet’s
chart, or on a receipt, to indicate that a
purchase of HEARTGARD has been made.
Target Display Area(s):
Pet’s chart, receipts submitted with
coupons/rebates
18
Compliance Aids
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Superior Protection Awards Program™ (SPAP)
Description:
Points program that rewards clinic staff
for promoting proper pet health care
Benefit:
SPAP is a reward program for clinic staff
that allows them to collect points when
they dispense large packs of FRONTLINE®
and HEARTGARD Brand Products.
Target Display Area(s):
Staff room
19
Compliance Aids
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
In-Clinic Dispensing Programs
Description:
Programs and promotions designed
to increase dispensing in clinic
Benefit:
Offers clinic staff additional opportunities to
open a dialog with clients about pet health
care issues and preventive medicine, and
also encourages monthly compliance.
Target Display Area(s):
Checkout area, reception area
20
Compliance Aids
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
The Plus Guarantee* of Satisfaction
Description:
The Plus Guarantee* supports the
outstanding performance of
HEARTGARD Plus
Benefit:
Allows vets and clinic staff to dispense
HEARTGARD with confidence, and
supports the following categories:
•Heartworm prevention
•Treatment and control of
roundworms and hookworms
• Palatability
Target Display Area(s):
Checkout area, waiting room, reception area
*Guarantee void where prohibited by law. Payment obligation by Merial shall be limited solely to that
which is represented in the official Plus Guarantee. Any and all other costs are expressly excluded.
21
Compliance Aids
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Direct-to-Consumer Communications (Website and TV Advertising)
Description:
HEARTGARD.com and HEARTGARD
consumer TV ads
Benefit:
The website is an educational resource
for consumers that offers information on
heartworm disease, roundworms and
hookworms and HEARTGARD Brand
Products, while TV advertising supports
heartworm disease awareness and
product recommendations.
22
ComplianceAids
Aids
Compliance
® ®
®
®
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
Vet-to-Pet Home Delivery
Description:
Home delivery service for FRONTLINE®
and HEARTGARD Brand Products
Benefit:
Supports the relationship between
vets and clients by offering clients a very
convenient service. This service also supports
compliance through regular monthly usage
of HEARTGARD Brand Products.
Target Display Area(s):
Checkout area, reception area, clinic windows
23
ComplianceAids
Aids
Compliance
® ®
®
®
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
Heartworm Testing Policy Plaque
Description:
Wall mounted display
Benefit:
A helpful tool that communicates the
importance of heartworm disease testing
and prevention as per American
Heartworm Society guidelines.
Target Display Area(s):
Waiting room and/or exam rooms
24
Compliance
Aids
Product Support Tools for
Clinic Staff
® ®
®
®
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
Fecal Parasite Examination Log Book
Description:
3-ring binder (with refill page
packs available)
Benefit:
Provides vets and clinic staff with a
convenient reference tool for use while
examining blood and fecal samples, and
helps facilitate and encourage best
practice in clinic.
Target Display Area(s):
Lab area
25
Support
Tools
ClinicStaff
Staff
ProductProduct
Support
Tools
forfor
Clinic
® ®
®
HEARTGARD
(ivermectin)
HEARTGARD
Plus ®(ivermectin/pyrantel)
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
Microscope Mat
Description:
Microscope mat with magnified
images of internal parasites
Benefit:
Provides vets and clinic staff with a
convenient reference tool for use while
examining blood and fecal samples.
Target Display Area(s):
Lab area
26
Product Support Tools for Clinic Staff
HEARTGARD ® (ivermectin) HEARTGARD® Plus (ivermectin/pyrantel)
Paws to Save Pets™
Description:
Paws to Save Pets was founded in 2006 in
response to the devastation left behind by
Hurricane Katrina and today continues to support
pets affected by disasters. Through the Petfinder.com
Foundation and the American Veterinary
Medical Foundation, Paws to Save Pets provides
disaster relief assistance and preparedness
to help ensure the health and well-being of
companion animals throughout the U.S.
Target Display Area(s):
To learn more visit www.pawstosavepets.com
27
Support
Tools
ClinicStaff
Staff
ProductProduct
Support
Tools
forfor
Clinic
® ®
®
HEARTGARD
(ivermectin)
HEARTGARD
Plus ®(ivermectin/pyrantel)
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
Clinic Staff Name Badge and Coaching Card
Description:
Name badges with magnetic closure
Benefit:
A functional tool that helps prompt discussion
between staff and clients on the importance
of monthly heartworm prevention, particularly
HEARTGARD Plus. The name badges are
accompanied by a laminated coaching card
that will aid clinic staff in communicating
key points on promoting year-round use of a
heartworm preventive.
Target Display Area(s):
Scrubs/front desk
28
Support
Tools
ClinicStaff
Staff
ProductProduct
Support
Tools
forfor
Clinic
® ®
®
HEARTGARD
(ivermectin)
HEARTGARD
Plus ®(ivermectin/pyrantel)
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
Professional Support for Technical Questions
Description:
Field-based and telephone technical support
Benefit:
Provides clinics with constant access to
information on products, disease states, etc.,
when they need it most simply by calling:
• 1-888-MERIAL-1 and selecting option 3, or
• your Merial Sales Representative
29
Support
Tools
ClinicStaff
Staff
ProductProduct
Support
Tools
forfor
Clinic
® ®
®
HEARTGARD
(ivermectin)
HEARTGARD
Plus ®(ivermectin/pyrantel)
HEARTGARD
(ivermectin)
HEARTGARD
Plus (ivermectin/pyrantel)
(www.vetmedteam.com)
Staff Training Programs
Description:
VETerinaire, Merial U and Merial EDU
Benefit:
Fun, interactive, educational programs
designed to provide vets and clinic staff with
information and support on disease states
and Merial products.
30
CHEWABLES
CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.
INDICATIONS: For use in cats to prevent feline heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after
infection, and for the removal and control of adult and immature hookworms (Ancylostoma tubaeforme and A. braziliense).
DOSAGE: HEARTGARD® (ivermectin) Chewables for Cats should be administered orally at monthly intervals at the recommended minimum dose level of 24 mcg of
ivermectin per kg (10.9 mcg/lb.) of body weight. The recommended dosage schedule for prevention of feline heartworm disease and control of hookworms is as follows:
Cat Weight
Lbs
HEARTGARD for Cats
Chewables per month
Ivermectin
content
up to 5
5 to 15
1
1
55 mcg
165 mcg
For cats over 15 lb., use the appropriate combination of chewables.
HEARTGARD Chewables for Cats is recommended for use in cats 6 weeks of age and older.
ADMINISTRATION: Remove only one Chewable at a time from the foil-backed blister card. Return the card with the remaining Chewables to its box to protect the product
from light. HEARTGARD Chewables for Cats can be offered to the cat by hand or may be added to a small amount of cat food. If manual dosing is required, the Chewable
should be broken into pieces for administration. Food should be routinely available during the day of treatment administration. If cats are fasted, or if the Chewable is not
broken into pieces for manual dosing, then reduced absorption may result. A relationship between reduced absorption and reduced efficacy has not been established.
Care should be taken to see that the cat consumes the complete dose. Treated animals should be observed for a few minutes after administration to ensure that part of the
dose is not lost or rejected. If it is suspected that any of the dose has been lost, redosing with a new Chewable is recommended. Fragments of Chewables have occasionally
been observed in the feces of some cats; efficacy of the product was not adversely affected.
HEARTGARD Chewables for Cats should be given at monthly intervals when mosquitoes potentially carrying infective heartworm larvae are active. The initial dose must be
given within a month (30 days) after the cat’s first exposure to mosquitoes. The final dose must be given within a month (30 days) after the cat’s last exposure to mosquitoes.
For optimal performance, HEARTGARD Chewables for Cats must be given once a month on or about the same date. If treatment is delayed, whether by a few days or
many, immediate treatment with HEARTGARD Chewables for Cats and resumption of the recommended dosing regimen will minimize the opportunity for development of
adult heartworm.
It is recommended that cats should be tested for existing heartworm infection prior to starting treatment with HEARTGARD Chewables for Cats. Cats already infected with adult
heartworms can safely be given HEARTGARD Chewables for Cats monthly to prevent further infections.
Monthly treatment with HEARTGARD Chewables for Cats also provides effective removal and control of adult and immature hookworms (A. tubaeforme and A. braziliense).
SAFETY: In the clinical studies involving more than 3000 doses of HEARTGARD Chewables for Cats, observations reported within 24 hours of treatment included vomition
in ≤ 0.3% and diarrhea in ≤ 0.2% of the doses administered. There were no statistical differences between HEARTGARD Chewables for Cats and the product vehicle
(control) for these observations.
A wide margin of safety was demonstrated in clinical trials at the recommended dose level in cats and kittens 6 weeks of age and older and in laboratory studies in cats with
circulating microfilariae of D. immitis. A wide margin of safety has also been demonstrated at 3 times the recommended dose in pregnant or breeding queens and breeding
toms. No adverse effects were observed in either male or female cats or their offspring in breeding studies. A 30-fold safety margin over the minimum recommended
dosage was established in a single dose tolerance study. In growing kittens dosed monthly for 8 consecutive doses, one cat given 5 times the market dose vomited and a
second cat in this group experienced diarrhea within 24 hours of the initial treatment. In clinical trials, many commonly used flea control products, anthelmintics, vaccines,
antibiotics and steroid preparations were administered with HEARTGARD Chewables for Cats without incident.
Keep this and all drugs out of the reach of children. In case of ingestion by humans, clients should be advised to contact a physician immediately.
STABILITY: HEARTGARD Chewables for Cats are stable for 2 years when stored below 77°F (25°C) and protected from light. Store at controlled room temperature of
68°F - 77°F (20°C - 25°C). Excursions between 59°F - 86°F (15°C - 30°C) are permitted.
HOW SUPPLIED: HEARTGARD Chewables for Cats is available in two dosage strengths (see DOSAGE section) for cats of different weights. Each strength comes in a
convenient carton of 6 chewables, packed 10 cartons per tray.
For customer assistance, please contact Merial at 1-888-637-4251.
31
CHEWABLES
CAUTION: Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.
INDICATIONS: For use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection
and for the treatment and control of ascarids (Toxocara canis, Toxascaris leonina) and hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense).
DOSAGE: HEARTGARD® Plus (ivermectin/pyrantel) Chewables should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of
ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight. The recommended dosing schedule for prevention of
canine heartworm disease and for the treatment and control of ascarids and hookworms is as follows:
Dog
Weight
Chewables
Per Month
Ivermectin
Content
Pyrantel
Content
Color Coding on
Foil-Backing
and Carton
Up to 25
26 - 50
51 - 100
1
1
1
68 mcg
136 mcg
272 mcg
57 mg
114 mg
227 mg
Blue
Green
Brown
HEARTGARD Plus is recommended for dogs 6 weeks of age and older. For dogs over 100 lb use the appropriate combination of these Chewables.
ADMINISTRATION: Remove only one chewable at a time from the foil-backed blister card. Return the card with the remaining Chewables to its box to protect the product
from light. Because most dogs find HEARTGARD Plus palatable, the product can be offered to the dog by hand. Alternatively, it may be added intact to a small amount of dog
food.The chewable should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Chewables may be broken into pieces
and fed to dogs that normally swallow treats whole.
Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes after administration to ensure that part of the
dose is not lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.
HEARTGARD Plus should be given at monthly intervals during the period of the year when mosquitoes (vectors), potentially carrying infective heartworm larvae, are active.
The initial dose must be given within a month (30 days) after the dog’s first exposure to mosquitoes. The final dose must be given within a month (30 days) after the dog’s
last exposure to mosquitoes.
When replacing another heartworm preventive product in a heartworm disease prevention program, the first dose of HEARTGARD Plus must be given within a month (30
days) of the last dose of the former medication.
If the interval between doses exceeds a month (30 days), the efficacy of ivermectin can be reduced. Therefore, for optimal performance, the Chewable must be given once
a month on or about the same day of the month. If treatment is delayed, whether by a few days or many, immediate treatment with HEARTGARD Plus and resumption of the
recommended dosing regimen will minimize the opportunity for the development of adult heartworms.
Monthly treatment with HEARTGARD Plus also provides effective treatment and control of ascarids (T. canis, T. leonina) and hookworms (A. caninum, U. stenocephala,
A. braziliense). Clients should be advised of measures to be taken to prevent reinfection with intestinal parasites.
EFFICACY: HEARTGARD Plus Chewables, given orally using the recommended dose and regimen, are effective against the tissue larval stage of D. immitis for
a month (30 days) after infection and, as a result, prevent the development of the adult stage. HEARTGARD Plus Chewables are also effective against canine ascarids (T. canis, T. leonina) and hookworms (A. caninum, U. stenocephala, A. braziliense).
ACCEPTABILITY: In acceptability and field trials, HEARTGARD Plus Chewables were shown to be an acceptable oral dosage form that was consumed at first offering by
the majority of dogs.
PRECAUTIONS: All dogs should be tested for existing heartworm infection before starting treatment with HEARTGARD Plus which is not effective against adult
D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with HEARTGARD Plus.
While some microfilariae may be killed by the ivermectin in HEARTGARD Plus at the recommended dose level, HEARTGARD Plus is not effective for microfilariae clearance.
A mild hypersensitivity-type reaction, presumably due to dead or dying microfilariae and particularly involving a transient diarrhea, has been observed in clinical trials with
ivermectin alone after treatment of some dogs that have circulating microfilariae.
Keep this and all drugs out of the reach of children.
In case of ingestion by humans, clients should be advised to contact a physician immediately. Physicians may contact a Poison Control Center for advice concerning cases
of ingestion by humans.
Store at controlled room temperature of 68°F - 77°F (20°C - 25°C). Excursions between 59°F - 86°F (15°C - 30°C) are permitted. Protect product from light.
ADVERSE REACTIONS: In clinical field trials with HEARTGARD Plus, vomiting or diarrhea within 24 hours of dosing was rarely observed (1.1% of administered doses).
The following adverse reactions have been reported following the use of HEARTGARD: Depression/lethargy, vomiting, anorexia, diarrhea, mydriasis, ataxia, staggering,
convulsions and hypersalivation.
SAFETY: HEARTGARD Plus has been shown to be bioequivalent to HEARTGARD, with respect to the bioavailability of ivermectin. The dose regimens of HEARTGARD Plus
and HEARTGARD are the same with regard to ivermectin (6 mcg/kg). Studies with ivermectin indicate that certain dogs of the Collie breed are more sensitive to the effects
of ivermectin administered at elevated dose levels (more than 16 times the target use level) than dogs of other breeds. At elevated doses, sensitive dogs showed adverse
reactions which included mydriasis, depression, ataxia, tremors, drooling, paresis, recumbency, excitability, stupor, coma and death. HEARTGARD demonstrated no signs of
toxicity at 10 times the recommended dose (60 mcg/kg) in sensitive Collies. Results of these trials and bioequivalency studies, support the safety of HEARTGARD products
in dogs, including Collies, when used as recommended.
HEARTGARD Plus has shown a wide margin of safety at the recommended dose level in dogs, including pregnant or breeding bitches, stud dogs and puppies aged 6 or
more weeks. In clinical trials, many commonly used flea collars, dips, shampoos, anthelmintics, antibiotics, vaccines and steroid preparations have been administered with
HEARTGARD Plus in a heartworm disease prevention program.
In one trial, where some pups had parvovirus, there was a marginal reduction in efficacy against intestinal nematodes, possibly due to a change in intestinal transit time.
HOW SUPPLIED: HEARTGARD Plus is available in three dosage strengths (see DOSAGE section) for dogs of different weights. Each strength comes in convenient cartons
of 6 and 12 Chewables.
For customer assistance, please contact Merial at 1-888-637-4251.
32